# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PDZ_1 PF12812.7 EJP60688.1 - 2.1e-09 37.3 0.0 4.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 PDZ-like domain Trypsin_2 PF13365.6 EJP60688.1 - 2.5e-07 31.7 0.6 4.1e-07 31.0 0.6 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 EJP60688.1 - 6.7e-05 22.7 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EJP60688.1 - 0.0011 19.2 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF31 PF01732.16 EJP60688.1 - 0.0025 17.4 0.6 0.003 17.1 0.6 1.1 1 0 0 1 1 1 1 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 EJP60688.1 - 0.0046 16.8 0.2 0.0092 15.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S29 PF02907.15 EJP60688.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 EJP60688.1 - 0.32 9.6 0.2 0.41 9.2 0.2 1.1 1 0 0 1 1 1 0 Peptidase S46 TPR_10 PF13374.6 EJP60690.1 - 2.7e-35 119.2 0.0 5.1e-12 45.3 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EJP60690.1 - 2e-26 92.0 0.1 5.7e-16 58.6 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EJP60690.1 - 3.3e-11 42.4 0.2 0.00045 20.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EJP60690.1 - 3.9e-09 36.3 0.2 0.0043 17.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJP60690.1 - 8.8e-07 28.6 0.0 0.072 13.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP60690.1 - 5.8e-06 26.7 0.0 0.016 15.7 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJP60690.1 - 7.6e-06 25.5 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP60690.1 - 9.3e-06 25.5 0.1 0.25 11.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP60690.1 - 5.4e-05 23.7 0.1 0.47 11.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP60690.1 - 0.00023 20.6 0.2 0.00027 20.4 0.2 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 EJP60690.1 - 0.0003 21.4 0.0 0.64 10.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJP60690.1 - 0.015 15.6 0.2 25 5.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EJP60690.1 - 0.02 14.9 0.0 6 7.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJP60690.1 - 0.14 12.9 0.2 38 5.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Trypsin_2 PF13365.6 EJP60691.1 - 1.5e-10 42.2 0.1 2.3e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_1 PF12812.7 EJP60691.1 - 1.5e-07 31.3 0.0 3.2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 PDZ-like domain PDZ_6 PF17820.1 EJP60691.1 - 4.9e-06 26.3 0.2 0.00029 20.6 0.1 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EJP60691.1 - 1.3e-05 25.4 0.0 0.00052 20.3 0.0 2.3 2 0 0 2 2 2 1 PDZ domain DUF31 PF01732.16 EJP60691.1 - 0.0035 16.9 0.4 0.0045 16.6 0.4 1.1 1 0 0 1 1 1 1 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 EJP60691.1 - 0.0052 16.6 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease PDZ PF00595.24 EJP60691.1 - 0.02 15.2 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Zn_clus PF00172.18 EJP60692.1 - 2.3e-08 34.0 9.3 4.3e-08 33.2 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP60692.1 - 0.026 13.6 0.5 0.052 12.6 0.5 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cep57_MT_bd PF06657.13 EJP60692.1 - 0.074 13.5 1.9 0.15 12.6 1.9 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Asn_synthase PF00733.21 EJP60693.1 - 1.7e-25 90.4 0.0 2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase DUF5372 PF17342.2 EJP60694.1 - 0.15 12.5 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5372) RVT_1 PF00078.27 EJP60696.1 - 2.8e-09 36.8 0.0 4.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 EJP60696.1 - 1e-05 25.3 1.3 0.044 13.7 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 EJP60697.1 - 3.8e-17 62.3 1.5 1.4e-16 60.5 0.4 2.3 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 EJP60697.1 - 5.2e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EJP60697.1 - 3.4e-05 23.7 4.4 3.4e-05 23.7 4.4 1.6 2 0 0 2 2 2 1 Zinc knuckle PI-TkoII_IV PF18714.1 EJP60697.1 - 0.042 13.3 0.2 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV zf-CCHC_6 PF15288.6 EJP60697.1 - 0.3 11.0 4.8 0.59 10.0 4.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EJP60697.1 - 0.43 10.3 1.2 0.86 9.4 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-BED PF02892.15 EJP60698.1 - 1.1 9.3 5.7 4.8 7.3 5.7 2.0 1 1 0 1 1 1 0 BED zinc finger Exo_endo_phos_2 PF14529.6 EJP60699.1 - 4.5e-24 84.6 0.0 9.3e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EJP60699.1 - 0.0021 17.6 0.0 0.004 16.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MRP-S26 PF14943.6 EJP60699.1 - 0.027 14.4 0.5 0.069 13.1 0.5 1.6 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Pkinase PF00069.25 EJP60700.1 - 7.9e-23 81.1 0.0 9.9e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP60700.1 - 2.4e-17 63.1 0.0 3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP60700.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EJP60700.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 EJP60701.1 - 1.5e-23 83.5 0.0 2.5e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP60701.1 - 2.4e-20 72.9 0.0 5.4e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EJP60701.1 - 0.0036 16.9 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EJP60701.1 - 0.011 15.7 1.3 0.038 13.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Chaperone_III PF07824.12 EJP60701.1 - 0.062 13.5 0.1 3.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Type III secretion chaperone domain TelA PF05816.11 EJP60702.1 - 0.026 13.6 1.1 0.03 13.4 1.1 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Rad4 PF03835.15 EJP60702.1 - 0.085 12.5 1.3 0.12 12.1 1.3 1.2 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain SUIM_assoc PF16619.5 EJP60702.1 - 0.2 11.7 1.1 0.43 10.7 0.1 1.8 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 OmpH PF03938.14 EJP60702.1 - 0.36 11.2 4.4 0.48 10.8 4.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RVT_1 PF00078.27 EJP60703.1 - 7e-09 35.5 0.1 7.3e-09 35.5 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAD_binding_3 PF01494.19 EJP60705.1 - 6.7e-74 249.2 0.0 1.4e-73 248.2 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.12 EJP60705.1 - 1e-37 129.7 0.1 1.9e-37 128.8 0.1 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EJP60705.1 - 6.4e-05 22.3 0.0 0.02 14.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP60705.1 - 0.0046 17.5 0.0 0.024 15.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP60705.1 - 0.011 15.3 0.1 0.15 11.6 0.0 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP60705.1 - 0.017 15.4 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 EJP60705.1 - 0.035 14.6 0.1 0.099 13.2 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain HI0933_like PF03486.14 EJP60705.1 - 0.14 10.8 0.0 0.29 9.8 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EJP60705.1 - 0.15 11.1 0.0 0.33 9.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 EJP60705.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IDO PF01231.18 EJP60706.1 - 1.6e-160 534.6 0.0 1.9e-160 534.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase NmrA PF05368.13 EJP60707.1 - 1.9e-14 53.8 0.0 3.9e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP60707.1 - 3.1e-14 53.3 0.0 5.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EJP60707.1 - 1e-13 51.3 0.1 2.1e-13 50.3 0.2 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EJP60707.1 - 1.9e-08 33.7 0.1 6.5e-08 31.9 0.1 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EJP60707.1 - 7e-08 32.2 0.1 1.1e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EJP60707.1 - 5e-05 22.8 0.0 7.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EJP60707.1 - 0.00023 20.4 0.0 0.01 15.0 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EJP60707.1 - 0.008 15.4 0.3 1.1 8.4 0.0 2.5 1 1 0 2 2 2 2 Male sterility protein adh_short_C2 PF13561.6 EJP60707.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP60707.1 - 0.047 13.6 0.1 0.88 9.5 0.0 2.6 3 0 0 3 3 3 0 KR domain Glu_dehyd_C PF16912.5 EJP60707.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus UCH PF00443.29 EJP60708.1 - 4.5e-44 150.9 1.6 5.7e-44 150.5 1.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJP60708.1 - 3.6e-19 69.5 5.5 4.7e-11 42.9 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Hydrophobin_2 PF06766.11 EJP60711.1 - 1.5e-06 28.0 5.3 1.7e-05 24.7 5.4 2.1 1 1 0 1 1 1 1 Fungal hydrophobin Rsa3 PF14615.6 EJP60712.1 - 6.1e-17 60.9 0.2 9.6e-17 60.3 0.2 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SNF2_N PF00176.23 EJP60713.1 - 5.6e-58 196.3 0.0 1e-57 195.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EJP60713.1 - 1.9e-36 125.9 0.4 2.6e-35 122.2 0.4 2.2 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 EJP60713.1 - 9.4e-17 61.4 0.0 3.4e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP60713.1 - 6.8e-10 39.2 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJP60713.1 - 3.8e-05 23.5 0.0 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EJP60713.1 - 0.00011 21.5 0.0 0.00086 18.6 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EJP60713.1 - 0.0041 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Chorismate_synt PF01264.21 EJP60714.1 - 3.7e-136 453.1 0.0 4.2e-136 453.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase tRNA-synt_1 PF00133.22 EJP60715.1 - 1.7e-218 726.8 0.0 2.5e-218 726.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EJP60715.1 - 8.2e-24 84.3 0.0 6e-23 81.5 0.0 2.4 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EJP60715.1 - 4.7e-15 55.2 0.0 2.1e-06 26.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EJP60715.1 - 0.0017 17.8 0.0 0.02 14.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF5011 PF16403.5 EJP60715.1 - 0.11 12.7 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) S1FA PF04689.13 EJP60716.1 - 0.34 11.1 0.9 0.78 9.9 0.9 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Pkinase PF00069.25 EJP60717.1 - 0.00012 21.6 0.0 0.00023 20.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP60717.1 - 0.00039 19.8 0.0 0.00079 18.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3723 PF12520.8 EJP60718.1 - 5.4e-52 177.1 0.1 5.4e-52 177.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) MerR-DNA-bind PF09278.11 EJP60718.1 - 0.023 15.2 0.1 0.023 15.2 0.1 4.2 3 1 1 4 4 4 0 MerR, DNA binding AGOG PF09171.10 EJP60720.1 - 0.076 12.3 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase SUN PF03856.13 EJP60721.1 - 4e-88 295.0 12.4 5e-88 294.7 12.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) RHSP PF07999.11 EJP60721.1 - 0.063 12.1 0.1 0.088 11.6 0.1 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein Mito_fiss_reg PF05308.11 EJP60721.1 - 0.79 9.8 5.4 1.3 9.1 5.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1180 PF06679.12 EJP60721.1 - 1.7 9.0 4.7 3.9 7.9 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Hist_deacetyl PF00850.19 EJP60722.1 - 1.3e-77 261.3 0.0 1.9e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain NAD_binding_6 PF08030.12 EJP60725.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Tubulin_C PF03953.17 EJP60726.1 - 5.5e-39 133.2 0.0 7.6e-39 132.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 EJP60726.1 - 1.5e-28 100.3 0.1 3.6e-28 99.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 EJP60726.1 - 7.4e-06 26.3 0.0 1.9e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF3435 PF11917.8 EJP60728.1 - 4.2e-24 85.2 1.5 4.2e-24 85.2 1.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) zf-C2H2_12 PF18658.1 EJP60728.1 - 0.045 13.3 0.4 0.44 10.1 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type FOXP-CC PF16159.5 EJP60728.1 - 0.34 11.6 3.2 0.3 11.8 1.0 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF2072 PF09845.9 EJP60728.1 - 0.95 9.7 3.9 0.66 10.2 1.2 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein sCache_like PF16736.5 EJP60728.1 - 4.9 7.3 5.7 0.63 10.1 0.3 2.2 3 0 0 3 3 3 0 Single Cache-like Peptidase_C48 PF02902.19 EJP60729.1 - 3.5e-18 66.3 0.1 5.7e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Dynamin_N PF00350.23 EJP60730.1 - 2.4e-34 118.8 0.0 5e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EJP60730.1 - 1e-22 80.7 1.3 1.3e-22 80.4 0.2 1.8 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 EJP60730.1 - 0.00036 20.6 0.2 0.0028 17.8 0.0 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EJP60730.1 - 0.00091 19.3 0.0 0.0096 16.0 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EJP60730.1 - 0.085 13.4 0.0 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Pet191_N PF10203.9 EJP60732.1 - 0.12 12.7 2.7 27 5.1 0.1 3.4 3 1 1 4 4 4 0 Cytochrome c oxidase assembly protein PET191 RXLR PF16810.5 EJP60733.1 - 0.64 10.5 3.9 0.78 10.2 3.7 1.3 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Alpha_GJ PF03229.13 EJP60733.1 - 2.2 8.8 9.1 2.8 8.5 9.1 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J CDC45 PF02724.14 EJP60734.1 - 0.024 13.0 1.5 0.027 12.8 1.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3081 PF11280.8 EJP60734.1 - 0.043 13.7 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) Apt1 PF10351.9 EJP60734.1 - 9.4 5.0 7.8 11 4.7 7.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PNP_UDP_1 PF01048.20 EJP60735.1 - 0.018 14.3 0.1 0.27 10.4 0.1 2.1 1 1 0 1 1 1 0 Phosphorylase superfamily MRVI1 PF05781.12 EJP60736.1 - 0.0072 15.1 1.1 0.0082 14.9 1.1 1.1 1 0 0 1 1 1 1 MRVI1 protein MMgT PF10270.9 EJP60737.1 - 1.6e-34 118.2 0.0 2.2e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.21 EJP60738.1 - 2.2e-42 145.2 0.0 5.2e-42 144.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EJP60738.1 - 9e-15 55.4 0.1 2e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EJP60738.1 - 3.1e-05 24.2 0.0 0.00011 22.5 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV NTP_transf_3 PF12804.7 EJP60738.1 - 0.0041 17.5 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 MobA-like NTP transferase domain AAA_14 PF13173.6 EJP60738.1 - 0.0064 16.5 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain T3SS_ATPase_C PF18269.1 EJP60738.1 - 0.016 15.0 0.1 0.11 12.3 0.0 2.4 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain ATPase_2 PF01637.18 EJP60738.1 - 0.023 14.6 0.0 0.57 10.0 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EJP60738.1 - 0.045 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EJP60738.1 - 0.15 12.3 0.2 0.71 10.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain zf-RVT PF13966.6 EJP60740.1 - 0.014 16.1 0.1 0.03 15.0 0.1 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_3 PF13456.6 EJP60740.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like WEMBL PF05701.11 EJP60741.1 - 0.00036 19.4 3.4 0.00043 19.1 3.4 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light LXG PF04740.12 EJP60741.1 - 0.0048 16.6 3.9 0.0061 16.3 3.9 1.2 1 0 0 1 1 1 1 LXG domain of WXG superfamily CENP-F_leu_zip PF10473.9 EJP60741.1 - 0.011 15.8 8.6 0.014 15.4 8.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 EJP60741.1 - 0.012 14.9 8.6 0.015 14.6 8.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein USP8_interact PF08941.10 EJP60741.1 - 0.022 14.6 5.9 0.03 14.1 5.9 1.3 1 0 0 1 1 1 0 USP8 interacting RPA_interact_M PF14767.6 EJP60741.1 - 0.032 14.8 1.4 0.032 14.8 1.4 1.9 2 0 0 2 2 2 0 Replication protein A interacting middle DUF1664 PF07889.12 EJP60741.1 - 0.035 14.2 3.2 0.05 13.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 EJP60741.1 - 0.037 14.3 2.4 0.046 14.0 2.4 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Golgin_A5 PF09787.9 EJP60741.1 - 0.038 13.4 15.9 0.043 13.3 15.9 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 EJP60741.1 - 0.05 12.7 10.3 0.056 12.5 10.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EJP60741.1 - 0.06 12.7 6.1 0.073 12.4 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMCO5 PF14992.6 EJP60741.1 - 0.12 12.0 8.3 0.16 11.5 7.9 1.4 1 1 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.19 EJP60741.1 - 0.12 10.3 4.0 0.14 10.0 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KLRAQ PF10205.9 EJP60741.1 - 0.14 12.4 9.4 0.038 14.2 5.7 1.9 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein INSC_LBD PF16748.5 EJP60741.1 - 0.19 11.2 1.8 0.87 9.1 0.3 2.3 2 0 0 2 2 2 0 Inscuteable LGN-binding domain OmpH PF03938.14 EJP60741.1 - 0.26 11.6 17.4 0.73 10.2 17.4 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF5113 PF17140.4 EJP60741.1 - 0.31 10.8 3.9 2.1 8.1 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5113) PRKG1_interact PF15898.5 EJP60741.1 - 0.46 11.4 14.1 0.14 13.1 9.9 1.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain PIN_3 PF13470.6 EJP60741.1 - 0.52 11.1 3.4 0.4 11.4 1.1 1.8 1 1 1 2 2 2 0 PIN domain DUF3847 PF12958.7 EJP60741.1 - 0.53 10.4 12.1 0.067 13.3 4.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) JIP_LZII PF16471.5 EJP60741.1 - 0.71 10.1 6.6 4.8 7.4 0.4 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 EJP60741.1 - 0.84 9.8 19.8 1.7 8.8 19.8 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 EJP60741.1 - 1 8.9 8.9 1.2 8.7 8.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 EJP60741.1 - 1.5 9.2 12.9 0.41 11.1 7.4 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF641 PF04859.12 EJP60741.1 - 2 8.7 10.1 12 6.3 10.0 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) FapA PF03961.13 EJP60741.1 - 2.1 6.9 4.2 2.4 6.7 4.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FUSC PF04632.12 EJP60741.1 - 2.4 6.6 9.3 2.7 6.4 9.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HIP1_clath_bdg PF16515.5 EJP60741.1 - 2.5 8.8 18.5 8.6 7.0 0.4 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 EJP60741.1 - 5.2 7.6 18.5 3.8 8.0 3.5 2.4 1 1 0 2 2 2 0 Cell division protein ZapB ADIP PF11559.8 EJP60741.1 - 7.1 6.7 18.4 0.9 9.6 8.2 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding BTB PF00651.31 EJP60742.1 - 1e-10 41.8 0.0 2.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Jnk-SapK_ap_N PF09744.9 EJP60744.1 - 0.006 16.8 2.5 0.006 16.8 2.5 2.6 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 EJP60744.1 - 0.065 13.5 11.8 0.59 10.4 2.2 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 EJP60744.1 - 0.57 9.6 8.5 0.99 8.9 0.8 2.4 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF848 PF05852.11 EJP60744.1 - 0.77 9.9 17.4 0.5 10.5 1.5 3.3 2 1 1 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) FapA PF03961.13 EJP60744.1 - 2.1 6.8 13.1 3.1 6.3 1.4 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A NAD_binding_6 PF08030.12 EJP60746.1 - 9.7e-10 38.8 0.0 1.6e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EJP60746.1 - 0.071 13.2 10.1 0.23 11.6 8.1 2.4 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF4405 PF14358.6 EJP60746.1 - 0.082 13.5 6.4 0.96 10.0 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Glyco_hydro_18 PF00704.28 EJP60747.1 - 3.6e-75 253.6 1.4 5.6e-75 253.0 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.32 EJP60747.1 - 0.00036 21.3 2.6 0.0044 17.8 0.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP60747.1 - 0.0013 19.0 0.0 0.025 14.9 0.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain SNARE PF05739.19 EJP60748.1 - 1.1e-09 38.1 1.0 2e-09 37.3 1.0 1.4 1 0 0 1 1 1 1 SNARE domain UbiA PF01040.18 EJP60750.1 - 9.1e-17 61.2 4.9 1.2e-16 60.8 4.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TMEM223 PF14640.6 EJP60750.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 223 ketoacyl-synt PF00109.26 EJP60751.1 - 4.1e-62 210.0 0.2 9e-62 208.9 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EJP60751.1 - 1.2e-53 181.7 0.0 2.5e-53 180.6 0.0 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EJP60751.1 - 3.6e-44 151.2 0.0 8e-44 150.1 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EJP60751.1 - 1.2e-39 136.7 0.2 2e-39 135.9 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP60751.1 - 3.4e-35 120.6 0.2 1.7e-34 118.4 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EJP60751.1 - 7.2e-20 71.6 0.0 2.6e-19 69.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP60751.1 - 5e-16 59.0 0.0 3.8e-15 56.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EJP60751.1 - 1.7e-13 51.0 0.0 3.9e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EJP60751.1 - 7.8e-13 48.9 0.0 3.6e-12 46.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EJP60751.1 - 9.1e-13 48.3 0.0 4.9e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 EJP60751.1 - 4.7e-11 42.7 0.0 1.5e-10 41.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 EJP60751.1 - 5.4e-11 42.7 0.0 1.7e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EJP60751.1 - 2.5e-10 40.8 0.0 8.2e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EJP60751.1 - 3.1e-10 39.9 0.0 3.4e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EJP60751.1 - 4.8e-08 34.1 0.0 3.2e-07 31.4 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP60751.1 - 1.7e-06 27.8 0.0 4.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 EJP60751.1 - 3.7e-06 26.5 0.0 9e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 EJP60751.1 - 7e-05 22.5 0.0 0.00028 20.5 0.0 2.1 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 EJP60751.1 - 0.00015 21.6 0.1 0.00058 19.6 0.0 1.9 2 0 0 2 2 2 1 Lysine methyltransferase Polysacc_synt_2 PF02719.15 EJP60751.1 - 0.00094 18.4 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EJP60751.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PCMT PF01135.19 EJP60751.1 - 0.011 15.6 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Thiolase_N PF00108.23 EJP60751.1 - 0.047 13.1 0.5 0.11 11.8 0.5 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EJP60751.1 - 0.052 13.4 1.1 0.16 11.9 0.1 2.4 3 0 0 3 3 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SAT PF16073.5 EJP60751.1 - 0.14 11.8 1.7 0.76 9.5 1.7 2.1 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_28 PF02636.17 EJP60751.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TRAP-delta PF05404.12 EJP60752.1 - 0.018 14.6 0.3 0.031 13.8 0.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) ABC_tran PF00005.27 EJP60753.1 - 1.5e-51 174.5 0.1 8.3e-29 100.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP60753.1 - 3.4e-34 118.8 19.6 1.8e-22 80.3 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP60753.1 - 2.3e-10 40.3 5.0 7.8e-05 22.2 0.2 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP60753.1 - 3.7e-07 30.2 4.9 0.017 14.9 0.2 3.7 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP60753.1 - 1.1e-06 28.2 1.2 0.014 15.2 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP60753.1 - 2.2e-05 24.4 0.1 0.37 10.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EJP60753.1 - 3.3e-05 23.9 0.1 0.059 13.4 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EJP60753.1 - 7.2e-05 23.4 0.3 0.11 13.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EJP60753.1 - 8.4e-05 22.4 0.0 0.048 13.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EJP60753.1 - 0.00092 19.0 0.5 0.23 11.2 0.3 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP60753.1 - 0.0015 19.0 0.8 0.62 10.4 0.3 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EJP60753.1 - 0.0017 18.7 0.3 2.2 8.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EJP60753.1 - 0.0099 15.5 0.1 1.4 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EJP60753.1 - 0.037 14.1 1.0 0.14 12.3 0.2 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 EJP60753.1 - 0.04 13.8 0.7 4.4 7.2 0.1 3.1 3 0 0 3 3 3 0 NTPase ATPase_2 PF01637.18 EJP60753.1 - 0.059 13.3 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EJP60753.1 - 0.17 11.0 0.4 4.1 6.5 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain TsaE PF02367.17 EJP60753.1 - 0.22 11.5 0.4 36 4.4 0.0 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EJP60753.1 - 0.43 10.8 1.5 29 4.9 0.1 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EJP60753.1 - 0.47 10.4 3.4 21 5.0 0.0 3.5 4 0 0 4 4 3 0 NACHT domain Dynamin_N PF00350.23 EJP60753.1 - 0.96 9.5 3.4 25 4.9 0.1 3.1 3 0 0 3 3 3 0 Dynamin family Pkinase PF00069.25 EJP60754.1 - 7.7e-16 58.2 0.0 9.8e-15 54.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP60754.1 - 1e-12 47.9 0.0 3.8e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP60754.1 - 5e-05 22.7 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP60754.1 - 0.0097 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EJP60754.1 - 0.034 13.7 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Beta-lactamase PF00144.24 EJP60755.1 - 5.6e-58 196.7 0.0 7.5e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Exo_endo_phos_2 PF14529.6 EJP60758.1 - 1.6e-14 53.8 0.0 4.1e-13 49.2 0.0 2.7 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EJP60758.1 - 3.4e-13 49.6 0.0 6.8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EJP60758.1 - 0.01 16.6 0.3 0.034 14.8 0.3 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNA_pol_Rpb2_6 PF00562.28 EJP60759.1 - 3e-127 424.9 0.2 5e-127 424.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EJP60759.1 - 3.2e-51 173.7 0.0 1.1e-50 172.0 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EJP60759.1 - 2.3e-45 154.6 0.0 4.3e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EJP60759.1 - 1.5e-33 115.1 0.1 3e-33 114.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EJP60759.1 - 1.9e-25 88.8 0.1 4.9e-25 87.5 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EJP60759.1 - 1.2e-23 83.4 0.4 3.4e-23 82.0 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 EJP60759.1 - 2e-19 69.6 0.2 6.2e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 PET117 PF15786.5 EJP60760.1 - 2.1e-25 88.8 3.6 2.4e-25 88.6 3.6 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial CTNNBL PF08216.11 EJP60761.1 - 1.3e-39 134.5 0.1 7.6e-39 132.1 0.0 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear DUF2779 PF11074.8 EJP60761.1 - 0.01 16.3 0.4 0.17 12.4 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) Tuberin PF03542.16 EJP60761.1 - 0.012 14.8 0.0 0.028 13.5 0.0 1.6 2 0 0 2 2 2 0 Tuberin Mo25 PF08569.11 EJP60761.1 - 0.048 13.0 2.0 0.057 12.8 0.7 1.8 2 1 0 2 2 2 0 Mo25-like DUF3361 PF11841.8 EJP60761.1 - 0.064 13.2 6.4 0.33 10.9 0.4 3.9 3 3 2 5 5 5 0 Domain of unknown function (DUF3361) Arm_3 PF16186.5 EJP60761.1 - 0.12 12.0 1.0 1.1 8.9 0.1 3.1 3 0 0 3 3 3 0 Atypical Arm repeat DUF2985 PF11204.8 EJP60762.1 - 6.3e-40 135.2 1.2 6.3e-40 135.2 1.2 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2985) DOPA_dioxygen PF08883.11 EJP60763.1 - 1.5e-30 105.5 0.0 2e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Apolipoprotein PF01442.18 EJP60768.1 - 0.004 17.0 2.2 0.0078 16.1 0.2 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 EJP60768.1 - 0.02 14.9 0.4 0.46 10.5 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FlgN PF05130.12 EJP60768.1 - 0.065 13.7 0.8 0.12 12.9 0.8 1.4 1 1 0 1 1 1 0 FlgN protein Abi_HHR PF07815.14 EJP60768.1 - 0.066 13.4 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Abl-interactor HHR Baculo_PEP_C PF04513.12 EJP60768.1 - 0.17 11.9 2.4 0.34 11.0 1.6 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sel1 PF08238.12 EJP60769.1 - 2.5e-11 43.9 25.5 0.0034 18.0 0.0 7.5 7 0 0 7 7 7 4 Sel1 repeat 5HT_transport_N PF03491.13 EJP60769.1 - 0.044 14.0 0.5 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus TPR_1 PF00515.28 EJP60769.1 - 0.053 13.4 1.3 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJP60769.1 - 0.065 13.5 0.3 0.065 13.5 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJP60769.1 - 0.23 12.2 1.9 9.6 7.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat EI24 PF07264.11 EJP60771.1 - 2.6e-08 34.3 19.7 7.2e-07 29.6 16.1 3.2 3 0 0 3 3 3 2 Etoposide-induced protein 2.4 (EI24) Ank PF00023.30 EJP60773.1 - 1.1e-05 25.6 0.1 0.0035 17.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EJP60773.1 - 0.0036 17.8 0.0 0.3 11.7 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP60773.1 - 0.0038 17.6 0.2 0.63 10.8 0.0 3.1 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EJP60773.1 - 0.024 15.2 0.1 0.36 11.5 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) HNH_2 PF13391.6 EJP60774.1 - 4.2e-15 55.6 0.2 1.1e-14 54.3 0.2 1.8 1 0 0 1 1 1 1 HNH endonuclease FAD_binding_8 PF08022.12 EJP60776.1 - 4.7e-05 23.4 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain dUTPase PF00692.19 EJP60776.1 - 0.062 13.0 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 dUTPase DUF2760 PF10816.8 EJP60776.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) DnaJ PF00226.31 EJP60777.1 - 1.5e-20 73.0 1.5 3.5e-20 71.9 1.5 1.6 1 0 0 1 1 1 1 DnaJ domain SGS PF05002.15 EJP60777.1 - 0.045 13.9 0.2 0.13 12.4 0.2 1.7 1 0 0 1 1 1 0 SGS domain Parvo_NS1 PF01057.17 EJP60777.1 - 0.057 12.5 0.7 0.1 11.7 0.4 1.5 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF5398 PF17376.2 EJP60777.1 - 0.11 13.1 0.8 1 10.0 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5398) DUF4936 PF16290.5 EJP60777.1 - 0.12 13.1 3.5 2.6 8.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) ABC_tran_CTD PF16326.5 EJP60777.1 - 0.12 12.6 5.2 0.47 10.7 3.2 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain COG5 PF10392.9 EJP60777.1 - 0.26 11.5 6.1 2.5 8.3 1.3 2.8 2 1 1 3 3 3 0 Golgi transport complex subunit 5 CRR7 PF12095.8 EJP60777.1 - 0.62 10.6 3.7 4.6 7.8 1.0 2.4 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Phlebovirus_NSM PF07246.11 EJP60777.1 - 1.3 8.4 8.1 0.8 9.0 4.0 2.3 1 1 2 3 3 3 0 Phlebovirus nonstructural protein NS-M PAS_9 PF13426.7 EJP60778.1 - 1.3e-25 89.7 0.0 5.4e-18 65.2 0.1 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 EJP60778.1 - 6.3e-21 74.5 0.0 5.8e-13 48.9 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 EJP60778.1 - 2.5e-15 55.8 8.0 4.8e-15 54.9 8.0 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 EJP60778.1 - 1.8e-14 53.7 1.9 1.8e-05 24.7 0.0 4.1 4 1 0 4 4 4 3 PAS fold PAS_11 PF14598.6 EJP60778.1 - 2.7e-08 33.9 0.0 0.01 15.9 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EJP60778.1 - 1.2e-07 31.9 0.0 0.0044 17.3 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 EJP60778.1 - 0.00052 20.7 0.0 1.6 9.5 0.0 3.5 3 0 0 3 3 3 1 PAS fold Glyco_transf_24 PF18404.1 EJP60779.1 - 4.8e-150 498.3 1.9 7.2e-150 497.8 1.9 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EJP60779.1 - 6.5e-68 229.4 0.0 2.2e-65 221.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EJP60779.1 - 7.5e-49 166.5 0.0 3e-48 164.6 0.0 2.1 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EJP60779.1 - 8.4e-42 143.2 0.1 7.4e-41 140.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EJP60779.1 - 3.9e-41 140.2 0.2 3.6e-39 133.8 0.2 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EJP60779.1 - 3.5e-39 133.3 0.0 6.8e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EJP60779.1 - 0.00018 21.2 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Coatomer_WDAD PF04053.14 EJP60780.1 - 6.6e-145 483.6 0.2 9.7e-145 483.0 0.2 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EJP60780.1 - 5e-96 321.9 0.0 6.5e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EJP60780.1 - 1.9e-35 120.2 17.3 1.8e-07 31.8 0.3 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP60780.1 - 1.7e-07 31.5 0.7 0.014 15.7 0.0 5.6 3 2 5 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP60780.1 - 0.041 12.5 4.4 1.2 7.6 0.9 3.5 2 1 1 4 4 4 0 Nucleoporin Nup120/160 IPPT PF01715.17 EJP60780.1 - 0.085 12.7 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 IPP transferase FIVAR PF07554.13 EJP60780.1 - 1.4 9.7 3.2 31 5.4 0.5 2.6 2 0 0 2 2 2 0 FIVAR domain CSN8_PSD8_EIF3K PF10075.9 EJP60781.1 - 1.3e-18 67.4 0.0 1.9e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EJP60781.1 - 0.053 12.9 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family Vac_Fusion PF02346.16 EJP60783.1 - 0.069 12.8 0.9 6 6.6 0.1 3.3 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Vault PF01505.18 EJP60783.1 - 0.1 12.8 1.0 0.45 10.7 0.0 2.5 2 0 0 2 2 2 0 Major Vault Protein repeat domain DUF2306 PF10067.9 EJP60784.1 - 1.4e-10 41.6 4.2 8.4e-10 39.0 4.2 2.0 1 1 0 1 1 1 1 Predicted membrane protein (DUF2306) NADH_dh_m_C1 PF15088.6 EJP60784.1 - 0.0089 15.6 4.6 0.18 11.4 0.1 3.3 2 1 1 3 3 3 2 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial zf-RING_5 PF14634.6 EJP60786.1 - 0.0015 18.5 1.2 0.0077 16.2 0.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EJP60786.1 - 0.0054 16.6 1.3 0.036 13.9 0.3 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EJP60786.1 - 0.013 15.5 1.6 0.033 14.2 1.6 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EJP60786.1 - 0.024 14.5 0.6 0.024 14.5 0.6 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP60786.1 - 0.11 12.8 2.8 0.14 12.5 0.7 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 EJP60786.1 - 0.17 11.8 3.2 0.18 11.7 0.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP60786.1 - 0.36 10.7 3.6 1.2 9.1 3.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.16 EJP60787.1 - 4.2e-23 81.8 32.2 4.2e-23 81.8 32.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP60787.1 - 4.2e-13 49.0 22.3 4.2e-13 49.0 22.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP60788.1 - 4.9e-33 114.5 24.3 4.9e-33 114.5 24.3 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Amidohydro_1 PF01979.20 EJP60788.1 - 5.2e-31 108.2 1.3 1.1e-30 107.2 1.3 1.5 1 0 0 1 1 1 1 Amidohydrolase family Abhydrolase_6 PF12697.7 EJP60788.1 - 6.6e-12 46.5 9.6 2.1e-11 44.9 4.7 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP60788.1 - 9.7e-08 32.0 0.8 1.7e-07 31.2 0.8 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Amidohydro_3 PF07969.11 EJP60788.1 - 0.0001 21.9 6.5 0.00073 19.1 1.4 2.3 2 0 0 2 2 2 2 Amidohydrolase family Esterase PF00756.20 EJP60788.1 - 0.25 10.9 0.5 0.55 9.8 0.5 1.5 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.18 EJP60789.1 - 9.9e-19 67.4 3.5 9.9e-19 67.4 3.5 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ig_J_chain PF15097.6 EJP60789.1 - 0.18 11.7 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin J chain RVT_1 PF00078.27 EJP60790.1 - 3e-40 138.1 0.0 5.6e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EJP60790.1 - 2.2e-21 75.9 2.8 8.6e-21 74.0 2.8 2.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EJP60790.1 - 1.9e-08 34.1 0.3 4e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C2H2 PF00096.26 EJP60790.1 - 0.00087 19.6 0.3 0.00087 19.6 0.3 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EJP60790.1 - 0.0097 16.2 0.3 0.0097 16.2 0.3 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EJP60790.1 - 0.018 15.8 0.2 0.018 15.8 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_5 PF13857.6 EJP60791.1 - 6.7e-21 74.1 2.4 2.4e-10 40.4 0.2 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP60791.1 - 1.9e-16 58.5 0.0 3.9e-05 23.7 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EJP60791.1 - 2.5e-16 60.0 0.0 3.1e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP60791.1 - 2e-15 56.9 0.0 1.3e-07 32.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EJP60791.1 - 1.6e-13 50.4 0.1 0.00055 20.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat AnkUBD PF18418.1 EJP60791.1 - 0.0046 17.1 0.1 0.031 14.4 0.0 2.2 1 1 2 3 3 3 1 Ankyrin ubiquitin-binding domain TA_inhibitor PF17574.2 EJP60791.1 - 0.066 13.2 0.2 1.2 9.2 0.2 2.3 1 1 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) DUF1800 PF08811.11 EJP60791.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) F-box-like PF12937.7 EJP60792.1 - 7.9e-06 25.7 0.3 2.2e-05 24.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP60792.1 - 0.0002 21.1 1.6 0.00067 19.5 1.6 2.0 1 0 0 1 1 1 1 F-box domain GATA PF00320.27 EJP60795.1 - 5.8e-14 51.4 3.5 1.3e-13 50.3 3.5 1.7 1 0 0 1 1 1 1 GATA zinc finger Carla_C4 PF01623.17 EJP60795.1 - 0.033 14.1 0.6 0.11 12.5 0.4 2.0 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein Fungal_trans_2 PF11951.8 EJP60796.1 - 6.3e-14 51.6 0.1 1.1e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_25 PF13649.6 EJP60797.1 - 3.6e-11 43.6 0.0 7.8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP60797.1 - 2.4e-09 37.3 0.0 3.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP60797.1 - 3.7e-08 33.9 0.0 8.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP60797.1 - 4.9e-05 23.2 0.0 0.00059 19.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP60797.1 - 0.0006 20.5 0.0 0.0016 19.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EJP60797.1 - 0.034 13.6 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.18 EJP60797.1 - 0.063 12.8 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 EJP60797.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CAP_assoc_N PF14504.6 EJP60799.1 - 0.0061 16.3 0.0 0.0083 15.9 0.0 1.1 1 0 0 1 1 1 1 CAP-associated N-terminal DUF573 PF04504.14 EJP60799.1 - 0.07 13.8 0.2 0.1 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Polysacc_deac_3 PF15421.6 EJP60799.1 - 0.19 10.2 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase Aminotran_3 PF00202.21 EJP60800.1 - 2e-56 191.4 0.0 2.2e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FAD_binding_3 PF01494.19 EJP60801.1 - 5e-13 49.0 0.0 1.6e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJP60801.1 - 0.021 14.5 0.6 0.047 13.3 0.6 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP60801.1 - 0.1 12.8 1.1 1.1 9.5 0.6 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 EJP60801.1 - 0.11 11.5 0.3 0.52 9.3 0.3 1.9 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 EJP60801.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Flavi_NS5 PF00972.20 EJP60803.1 - 0.11 10.6 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Ion_trans PF00520.31 EJP60806.1 - 4.2e-115 383.1 74.1 1e-42 146.1 3.1 4.9 4 1 0 4 4 4 4 Ion transport protein EF-hand_7 PF13499.6 EJP60806.1 - 0.055 13.9 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair JSRP PF15312.6 EJP60806.1 - 0.15 12.0 0.0 0.6 10.1 0.0 2.0 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein PHD PF00628.29 EJP60807.1 - 3.5e-08 33.2 9.5 6.9e-08 32.3 9.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EJP60807.1 - 0.076 12.6 6.2 0.16 11.6 6.2 1.5 1 0 0 1 1 1 0 PHD-finger eIF3_N PF09440.10 EJP60807.1 - 0.47 10.9 4.1 1.3 9.5 4.1 1.7 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain HMG_box PF00505.19 EJP60808.1 - 8e-12 45.4 0.2 4.6e-11 43.0 0.1 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EJP60808.1 - 0.0018 18.8 0.2 0.0038 17.8 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 EJP60808.1 - 0.023 14.0 0.0 0.062 12.6 0.0 1.7 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box AP_endonuc_2 PF01261.24 EJP60809.1 - 2.2e-29 102.4 0.0 2.9e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.12 EJP60810.1 - 2.2e-42 143.9 0.5 4.2e-42 143.0 0.5 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EJP60810.1 - 4.3e-08 32.8 0.0 3.8e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.11 EJP60810.1 - 2.6e-06 27.5 0.0 5.1e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 APH PF01636.23 EJP60810.1 - 0.017 15.1 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EJP60810.1 - 0.024 13.9 0.0 0.087 12.1 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase DUF5315 PF17242.2 EJP60811.1 - 1.5e-27 95.2 1.2 1.6e-26 92.0 1.0 2.5 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Ribosom_S12_S23 PF00164.25 EJP60812.1 - 3.8e-51 171.5 0.6 4.7e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UbiA PF01040.18 EJP60813.1 - 3.9e-39 134.5 12.8 4.7e-39 134.2 12.8 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-4CXXC_R1 PF10497.9 EJP60814.1 - 4.6e-09 36.4 10.9 4.6e-09 36.4 10.9 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 JmjC PF02373.22 EJP60814.1 - 9.5e-08 32.5 0.1 3.1e-07 30.8 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase PPTA PF01239.22 EJP60816.1 - 1.9e-34 116.4 15.8 8.6e-10 38.0 0.1 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat GLTT PF01744.20 EJP60818.1 - 0.11 12.3 0.3 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 GLTT repeat (6 copies) GATA PF00320.27 EJP60819.1 - 1.9e-15 56.1 4.7 4.3e-15 55.0 4.7 1.6 1 0 0 1 1 1 1 GATA zinc finger TPR_1 PF00515.28 EJP60820.1 - 5.1e-05 22.9 6.4 0.13 12.2 0.4 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EJP60820.1 - 6.4e-05 22.7 14.9 0.0037 17.1 0.1 6.1 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP60820.1 - 9.1e-05 22.7 16.7 0.12 12.7 0.8 4.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP60820.1 - 0.00031 20.2 7.9 0.033 13.5 1.4 2.8 1 1 2 3 3 3 2 MalT-like TPR region TPR_16 PF13432.6 EJP60820.1 - 0.24 12.1 17.8 0.2 12.3 8.2 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EJP60820.1 - 0.98 9.6 14.1 2.2 8.5 0.2 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EJP60820.1 - 1.9 9.0 11.3 0.46 11.0 2.4 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EJP60820.1 - 3.9 7.8 16.4 0.98 9.7 1.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3435 PF11917.8 EJP60822.1 - 1.8e-30 106.2 0.1 2.6e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Sulfotransfer_4 PF17784.1 EJP60822.1 - 0.15 11.9 2.3 0.2 11.4 1.1 1.9 2 1 0 2 2 2 0 Sulfotransferase domain zf-C2H2_2 PF12756.7 EJP60823.1 - 0.02 15.2 0.6 0.1 12.9 0.8 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CDC45 PF02724.14 EJP60824.1 - 0.21 9.9 11.1 0.34 9.1 11.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Phage_cap_E PF03864.15 EJP60825.1 - 0.034 13.3 0.1 0.042 13.0 0.1 1.1 1 0 0 1 1 1 0 Phage major capsid protein E Nop14 PF04147.12 EJP60827.1 - 0.0027 16.0 9.9 0.0027 16.0 9.9 1.4 2 0 0 2 2 2 1 Nop14-like family CDC27 PF09507.10 EJP60827.1 - 0.086 12.2 14.1 0.16 11.4 14.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 EJP60827.1 - 0.35 9.1 12.3 0.67 8.2 12.3 1.4 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EJP60827.1 - 2 6.4 19.2 2.9 5.9 19.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 EJP60827.1 - 8.1 6.1 23.2 0.17 11.6 16.2 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 EJP60827.1 - 8.6 5.9 20.5 0.58 9.7 14.9 1.8 2 0 0 2 2 2 0 PPP4R2 RGS PF00615.19 EJP60828.1 - 7.8e-11 42.3 0.0 1.1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAO PF01266.24 EJP60829.1 - 3e-51 175.1 0.0 6e-51 174.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EJP60829.1 - 2.5e-43 147.0 0.0 5.1e-43 145.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase Cupin_8 PF13621.6 EJP60829.1 - 6.5e-34 117.8 0.0 1.2e-33 117.0 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 EJP60829.1 - 4.8e-23 82.1 0.0 7.5e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EJP60829.1 - 6.4e-05 22.9 4.0 0.00049 20.0 0.1 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain FAD_binding_2 PF00890.24 EJP60829.1 - 8.5e-05 21.8 1.0 0.00022 20.4 1.0 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EJP60829.1 - 0.003 17.0 0.3 0.012 15.0 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP60829.1 - 0.0032 16.8 0.1 0.036 13.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Cupin_4 PF08007.12 EJP60829.1 - 0.0093 15.5 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Pyr_redox PF00070.27 EJP60829.1 - 0.016 15.7 0.5 0.15 12.7 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP60829.1 - 0.017 15.3 0.2 0.052 13.8 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EJP60829.1 - 0.021 14.1 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP60829.1 - 0.071 11.8 0.2 0.13 10.9 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EJP60829.1 - 0.16 11.2 0.1 0.67 9.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Orthopox_F8 PF05886.11 EJP60830.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Orthopoxvirus F8 protein DUF1435 PF07256.12 EJP60831.1 - 1.7 8.8 8.5 6.7 6.9 0.9 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1435) TMEMspv1-c74-12 PF11044.8 EJP60831.1 - 9.3 6.3 11.5 2 8.4 0.1 3.3 4 0 0 4 4 4 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Raptor_N PF14538.6 EJP60834.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain SCP_3 PF17844.1 EJP60834.1 - 0.08 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial SCP ortholog Dimer_Tnp_hAT PF05699.14 EJP60835.1 - 5.8e-24 83.7 0.1 1.4e-23 82.4 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 EJP60835.1 - 0.0024 17.7 0.0 0.0082 16.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 EJP60835.1 - 0.049 13.7 6.2 0.11 12.6 6.2 1.6 1 0 0 1 1 1 0 BED zinc finger DUF4413 PF14372.6 EJP60835.1 - 0.11 12.8 0.3 0.91 9.9 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) Tup_N PF08581.10 EJP60836.1 - 0.034 14.4 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Tup N-terminal Ank_2 PF12796.7 EJP60837.1 - 4.1e-33 113.8 0.0 8.4e-08 32.7 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP60837.1 - 1.2e-23 83.1 0.6 2.1e-09 37.7 0.0 5.5 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP60837.1 - 2.6e-20 70.3 0.9 0.0002 21.5 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EJP60837.1 - 2.6e-18 65.8 2.6 5.8e-11 42.4 0.0 5.1 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EJP60837.1 - 6.8e-18 64.2 1.1 5e-05 23.6 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat VWA_3_C PF18571.1 EJP60837.1 - 0.052 13.4 0.0 0.83 9.6 0.0 2.6 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain AAA_12 PF13087.6 EJP60838.1 - 1.4e-25 90.1 0.0 2.3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP60838.1 - 0.00016 21.4 0.2 0.035 13.8 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EJP60838.1 - 0.00017 21.5 0.0 0.089 12.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EJP60838.1 - 0.0011 18.5 0.1 0.0032 17.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EJP60838.1 - 0.0094 15.7 0.0 2.9 7.6 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EJP60838.1 - 0.038 13.8 0.1 0.47 10.3 0.0 2.8 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EJP60838.1 - 0.051 13.9 0.0 0.93 9.8 0.1 2.8 4 0 0 4 4 4 0 AAA domain ResIII PF04851.15 EJP60838.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PAF-AH_p_II PF03403.13 EJP60839.1 - 3.6e-47 160.7 0.0 1.8e-22 79.4 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EJP60839.1 - 9e-08 31.3 0.0 6.4e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 EJP60839.1 - 4e-05 22.8 0.0 0.00092 18.3 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.8 EJP60839.1 - 5.9e-05 22.4 0.1 0.037 13.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP60839.1 - 0.05 14.2 0.8 0.62 10.6 0.4 2.7 3 1 0 3 3 3 0 Alpha/beta hydrolase family CBS PF00571.28 EJP60841.1 - 1.1e-15 57.8 1.1 1.8e-05 25.1 0.1 4.5 4 0 0 4 4 4 4 CBS domain Rubella_E2 PF05749.11 EJP60841.1 - 0.012 15.2 0.4 0.012 15.2 0.4 1.8 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 Aminotran_1_2 PF00155.21 EJP60843.1 - 2.5e-39 135.5 0.0 3e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EJP60843.1 - 0.0017 17.0 0.0 0.0028 16.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.15 EJP60844.1 - 0 1369.0 0.0 0 1368.2 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EJP60844.1 - 1.9e-43 147.8 1.2 8.6e-43 145.8 1.2 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.9 EJP60845.1 - 5.6e-38 129.3 1.3 1e-37 128.4 0.6 1.8 2 0 0 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 EJP60845.1 - 1.3e-07 31.4 5.2 2.8e-07 30.3 5.2 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain YABBY PF04690.13 EJP60845.1 - 0.00078 20.0 0.1 0.0032 18.0 0.1 2.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.19 EJP60845.1 - 0.0027 18.1 0.1 0.0086 16.5 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box Peptidase_M91 PF14891.6 EJP60845.1 - 0.05 13.9 0.1 0.17 12.2 0.1 1.9 1 0 0 1 1 1 0 Effector protein DUF4379 PF14311.6 EJP60845.1 - 0.14 12.6 4.8 0.53 10.7 4.8 2.1 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 EJP60845.1 - 0.16 12.1 1.3 0.46 10.6 1.3 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 EJP60845.1 - 0.19 12.0 2.4 0.45 10.9 2.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon Mog1 PF04603.12 EJP60846.1 - 1.1e-38 132.7 0.0 1.3e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein HIT PF01230.23 EJP60847.1 - 4.4e-15 56.2 0.0 6e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EJP60847.1 - 1.9e-08 34.8 0.0 2.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding ICAT PF06384.11 EJP60847.1 - 0.003 17.7 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT CwfJ_C_1 PF04677.15 EJP60847.1 - 0.0072 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.6 EJP60847.1 - 0.0093 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 CRAL_TRIO PF00650.20 EJP60848.1 - 1.7e-42 144.9 0.0 2.4e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJP60848.1 - 1.6e-13 50.6 0.2 4.2e-13 49.3 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EJP60848.1 - 6.5e-07 29.6 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Adaptin_N PF01602.20 EJP60849.1 - 2.6e-93 313.4 8.7 2.6e-93 313.4 8.7 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EJP60849.1 - 7.5e-61 204.1 0.7 1.6e-60 203.1 0.7 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EJP60849.1 - 5.3e-56 188.1 0.0 1.4e-55 186.7 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EJP60849.1 - 8.6e-14 51.9 5.7 6.5e-10 39.3 0.0 3.0 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJP60849.1 - 5.3e-08 33.1 3.3 0.00052 20.3 0.0 4.6 2 2 2 4 4 4 3 HEAT repeats Coatomer_g_Cpla PF16381.5 EJP60849.1 - 0.00048 20.2 0.0 0.0022 18.1 0.0 2.2 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EJP60849.1 - 0.0093 16.2 1.1 11 6.6 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat AP4E_app_platf PF14807.6 EJP60849.1 - 0.042 14.2 0.3 0.17 12.2 0.3 2.1 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 EJP60849.1 - 0.22 12.0 2.7 14 6.3 0.0 4.5 5 0 0 5 5 5 0 HEAT-like repeat Mago_nashi PF02792.14 EJP60850.1 - 2.8e-71 238.2 0.1 3.1e-71 238.1 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.9 EJP60851.1 - 6.5e-64 214.6 1.0 8.5e-64 214.2 1.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0020 PF01170.18 EJP60852.1 - 2.9e-08 33.6 0.1 1.9e-06 27.7 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Ribonuc_P_40 PF08584.11 EJP60853.1 - 2.4e-30 105.8 0.0 3.3e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.6 EJP60854.1 - 3.9e-09 36.6 0.2 1.2e-08 35.1 0.2 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EJP60854.1 - 6.4e-06 26.6 0.0 4.1e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP60854.1 - 9.4e-05 22.5 1.3 0.00029 21.0 0.5 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EJP60854.1 - 0.00014 22.3 0.1 0.00023 21.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DALR_2 PF09190.11 EJP60854.1 - 0.011 16.3 0.3 0.082 13.4 0.0 2.4 2 1 1 3 3 3 0 DALR domain Ank PF00023.30 EJP60854.1 - 0.052 14.0 0.4 0.12 12.8 0.4 1.7 1 0 0 1 1 1 0 Ankyrin repeat RNA_lig_T4_1 PF09511.10 EJP60855.1 - 2e-86 289.4 0.0 3.5e-86 288.6 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 EJP60855.1 - 1.3e-76 257.4 0.0 2.1e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 EJP60855.1 - 2e-53 180.9 0.0 4.9e-53 179.6 0.0 1.7 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 EJP60855.1 - 0.0041 17.7 0.5 0.057 14.0 0.0 3.3 4 1 0 4 4 4 1 AAA domain Ribosomal_L10 PF00466.20 EJP60857.1 - 0.00047 20.2 0.0 0.006 16.7 0.0 2.2 2 1 0 2 2 2 1 Ribosomal protein L10 AAA PF00004.29 EJP60858.1 - 1e-39 136.0 0.0 1.8e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EJP60858.1 - 1.1e-18 66.9 0.1 2.3e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EJP60858.1 - 4.3e-08 32.8 0.0 9.8e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EJP60858.1 - 9.8e-05 22.8 1.7 0.013 15.9 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EJP60858.1 - 0.0003 20.8 0.1 0.0014 18.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EJP60858.1 - 0.00038 20.2 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EJP60858.1 - 0.0015 18.6 0.0 0.013 15.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EJP60858.1 - 0.0017 18.6 1.9 0.083 13.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 EJP60858.1 - 0.0028 17.1 0.2 0.073 12.5 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EJP60858.1 - 0.0099 15.3 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EJP60858.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EJP60858.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EJP60858.1 - 0.068 12.9 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EJP60858.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EJP60858.1 - 0.17 11.4 0.0 0.46 10.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EJP60858.1 - 0.46 10.2 4.2 0.55 10.0 0.0 2.6 2 1 0 3 3 3 0 AAA domain DUF4065 PF13274.6 EJP60858.1 - 0.84 10.5 2.7 2.1 9.3 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) BOP1NT PF08145.12 EJP60859.1 - 3.2e-105 351.7 5.1 5.2e-105 351.0 5.1 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EJP60859.1 - 2.4e-24 85.2 6.9 6.5e-12 45.8 0.2 6.1 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP60859.1 - 5.4e-06 26.6 0.0 0.019 15.3 0.0 4.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP60859.1 - 0.042 12.8 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ish1 PF10281.9 EJP60860.1 - 1.4e-79 262.1 21.0 4.3e-13 49.3 0.1 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EJP60860.1 - 2.6e-09 36.6 0.0 0.56 10.0 0.0 6.9 9 0 0 9 9 9 3 SAP domain Slx4 PF09494.10 EJP60860.1 - 4.9e-07 29.6 1.8 12 6.0 0.0 7.0 7 0 0 7 7 7 1 Slx4 endonuclease HeH PF12949.7 EJP60860.1 - 5.2e-06 26.1 0.0 9.4 6.1 0.0 5.4 6 0 0 6 6 6 1 HeH/LEM domain DUF4224 PF13986.6 EJP60860.1 - 0.001 18.9 0.0 5.8 6.9 0.0 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF4224) Phage_CRI PF05144.14 EJP60860.1 - 0.063 12.6 0.2 0.063 12.6 0.2 1.7 2 0 0 2 2 2 0 Phage replication protein CRI EF-hand_9 PF14658.6 EJP60860.1 - 0.074 13.4 0.0 26 5.3 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain PG_binding_1 PF01471.18 EJP60860.1 - 0.15 12.3 0.6 14 6.0 0.3 3.9 5 0 0 5 5 5 0 Putative peptidoglycan binding domain Apolipoprotein PF01442.18 EJP60860.1 - 2.3 8.0 18.2 0.24 11.3 1.6 3.9 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain zf-CCHC_4 PF14392.6 EJP60861.1 - 0.24 11.2 0.7 0.44 10.3 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle NOA36 PF06524.12 EJP60861.1 - 2.4 7.4 15.6 5.9 6.1 15.6 1.6 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 EJP60863.1 - 5.2e-18 65.4 0.0 6.8e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP60863.1 - 6.2e-08 32.2 0.0 7.8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP60863.1 - 4e-06 25.9 0.0 5.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EJP60863.1 - 0.0028 17.6 0.0 0.0098 15.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF202 PF02656.15 EJP60867.1 - 1.4 9.4 5.7 20 5.7 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase_fungal PF17667.1 EJP60869.1 - 1.3e-126 422.7 1.4 1.6e-126 422.4 1.4 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EJP60869.1 - 8.5e-09 35.1 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP60869.1 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP60869.1 - 0.0097 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3723 PF12520.8 EJP60870.1 - 3.5e-07 29.3 0.1 3.5e-07 29.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) DUF848 PF05852.11 EJP60870.1 - 0.13 12.4 17.3 0.45 10.6 1.9 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) bZIP_1 PF00170.21 EJP60870.1 - 0.67 10.1 9.7 6 7.0 0.1 3.3 3 0 0 3 3 3 0 bZIP transcription factor ZapB PF06005.12 EJP60870.1 - 6.4 7.3 25.7 6.7 7.2 6.9 3.8 2 1 1 3 3 3 0 Cell division protein ZapB Glutaminase PF04960.15 EJP60873.1 - 4.7e-114 380.4 0.1 5.9e-114 380.1 0.1 1.1 1 0 0 1 1 1 1 Glutaminase STAS PF01740.21 EJP60873.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EJP60873.1 - 0.056 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 STAS domain Arginosuc_synth PF00764.19 EJP60874.1 - 1.3e-140 469.1 0.0 1.5e-140 468.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.16 EJP60874.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase MFS_1 PF07690.16 EJP60875.1 - 1.5e-34 119.5 16.6 1.5e-34 119.5 16.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidohydro_3 PF07969.11 EJP60876.1 - 1.3e-77 262.3 2.0 1.9e-77 261.7 2.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EJP60876.1 - 1.3e-13 51.0 0.4 3.1e-10 39.9 0.0 2.8 3 1 0 3 3 3 2 Amidohydrolase family PS_Dcarbxylase PF02666.15 EJP60877.1 - 1.5e-56 191.1 0.3 1.9e-56 190.8 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M43 PF05572.13 EJP60878.1 - 9.9e-15 54.8 0.1 1.9e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EJP60878.1 - 0.0043 17.6 0.2 0.016 15.8 0.2 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EJP60878.1 - 0.079 13.1 3.7 0.36 10.9 3.7 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 EJP60878.1 - 0.15 11.0 0.3 0.21 10.5 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 EJP60878.1 - 0.28 9.8 0.5 0.38 9.3 0.5 1.1 1 0 0 1 1 1 0 Putative peptidase family Sulfatase PF00884.23 EJP60879.1 - 1.6e-72 244.5 0.0 2.4e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EJP60879.1 - 0.0069 15.0 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 EJP60879.1 - 0.03 14.6 0.2 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) DUF4994 PF16385.5 EJP60879.1 - 0.081 12.8 0.2 0.24 11.3 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function Sulfatase_C PF14707.6 EJP60879.1 - 0.16 12.7 0.3 1 10.1 0.3 2.2 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase MFS_1 PF07690.16 EJP60880.1 - 6.3e-28 97.7 22.1 6.3e-28 97.7 22.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EJP60880.1 - 0.0012 17.8 0.0 0.0029 16.5 0.0 1.8 1 1 0 1 1 1 1 MFS_1 like family F-box_4 PF15966.5 EJP60882.1 - 4e-06 26.7 0.1 1.4e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 F-box F-box PF00646.33 EJP60882.1 - 9.9e-06 25.3 0.3 4.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EJP60882.1 - 0.00068 19.5 0.2 0.0016 18.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like ZapD PF07072.11 EJP60882.1 - 0.0038 17.0 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Cell division protein EZH2_N PF18601.1 EJP60882.1 - 0.16 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 EZH2 N-terminal domain HNH_2 PF13391.6 EJP60883.1 - 1.7e-06 28.1 0.0 5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease AAA_12 PF13087.6 EJP60885.1 - 1.6e-41 142.1 0.1 1.1e-40 139.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EJP60885.1 - 4.6e-39 133.9 0.2 2.2e-12 47.5 0.0 5.7 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EJP60885.1 - 9.1e-24 84.6 23.3 1.1e-21 77.9 0.0 6.2 6 0 0 6 6 5 2 AAA domain AAA_30 PF13604.6 EJP60885.1 - 1e-21 77.6 0.1 3.3e-05 23.7 0.0 5.9 5 0 0 5 5 5 5 AAA domain AAA_lid_6 PF17866.1 EJP60885.1 - 1.3e-21 76.6 5.3 5.2e-09 36.2 0.6 4.0 3 0 0 3 3 3 2 AAA lid domain AAA_19 PF13245.6 EJP60885.1 - 3.1e-15 56.8 0.0 3.1e-07 30.8 0.0 5.4 4 1 0 4 4 4 1 AAA domain AAA_16 PF13191.6 EJP60885.1 - 1.7e-13 51.3 3.2 0.0033 17.8 0.2 5.2 4 0 0 4 4 4 3 AAA ATPase domain AAA_5 PF07728.14 EJP60885.1 - 8e-12 45.3 3.1 0.083 12.9 0.0 5.3 5 0 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EJP60885.1 - 1.6e-10 41.4 14.5 0.012 15.9 0.7 7.6 5 2 0 5 5 4 2 AAA domain AAA_33 PF13671.6 EJP60885.1 - 4e-07 30.3 3.1 0.59 10.3 0.1 5.0 4 0 0 4 4 4 2 AAA domain Mg_chelatase PF01078.21 EJP60885.1 - 1.1e-06 28.2 1.0 0.98 8.8 0.0 5.0 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EJP60885.1 - 1.2e-06 28.4 0.1 0.54 10.0 0.0 4.8 4 0 0 4 4 4 1 IstB-like ATP binding protein RuvB_N PF05496.12 EJP60885.1 - 1.3e-06 28.3 0.4 1.1 9.0 0.0 4.2 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EJP60885.1 - 2.2e-06 28.0 0.0 6.4 7.2 0.0 4.9 4 0 0 4 4 4 0 RNA helicase Torsin PF06309.11 EJP60885.1 - 5.1e-05 23.4 0.0 19 5.4 0.0 4.6 4 0 0 4 4 4 0 Torsin AAA_24 PF13479.6 EJP60885.1 - 7.9e-05 22.5 4.3 1.3 8.7 0.1 4.7 4 0 0 4 4 4 1 AAA domain ResIII PF04851.15 EJP60885.1 - 9.8e-05 22.4 0.3 0.34 10.9 0.0 4.7 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EJP60885.1 - 0.0006 19.2 8.8 0.19 10.9 0.0 6.5 7 0 0 7 7 7 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EJP60885.1 - 0.0011 18.5 1.6 1.7 8.1 0.0 4.3 4 0 0 4 4 4 1 PhoH-like protein AAA_7 PF12775.7 EJP60885.1 - 0.0021 17.6 2.3 13 5.2 0.0 4.1 4 0 0 4 4 4 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EJP60885.1 - 0.0024 17.8 3.5 13 5.7 0.0 4.0 4 0 0 4 4 4 0 NTPase AAA_18 PF13238.6 EJP60885.1 - 0.0026 18.3 13.6 4 8.0 0.0 5.5 5 0 0 5 5 4 1 AAA domain Helicase_RecD PF05127.14 EJP60885.1 - 0.07 13.0 0.0 0.64 9.8 0.0 2.8 2 0 0 2 2 2 0 Helicase TsaE PF02367.17 EJP60885.1 - 0.12 12.4 1.2 28 4.7 0.0 3.7 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EJP60885.1 - 0.35 10.5 2.5 3.5 7.2 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EJP60885.1 - 0.4 10.2 5.9 44 3.6 0.0 5.0 4 1 0 5 5 5 0 AAA domain ABC_tran PF00005.27 EJP60885.1 - 3.3 8.2 10.2 33 5.0 0.1 4.9 5 0 0 5 5 4 0 ABC transporter Vanabin-2 PF11437.8 EJP60885.1 - 3.5 7.8 13.7 12 6.2 13.7 1.9 1 0 0 1 1 1 0 Vanadium-binding protein 2 Piwi PF02171.17 EJP60886.1 - 4.8e-68 229.6 0.0 9.5e-68 228.6 0.0 1.5 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EJP60886.1 - 3.7e-15 55.3 0.5 7.9e-15 54.3 0.5 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 EJP60886.1 - 1.6e-13 51.5 0.1 1.3e-12 48.5 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 EJP60886.1 - 9.7e-08 31.9 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 EJP60886.1 - 2.4e-07 31.0 0.0 6.7e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EJP60886.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute DUF659 PF04937.15 EJP60887.1 - 0.019 14.8 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) TAXi_C PF14541.6 EJP60887.1 - 0.042 13.6 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Dimer_Tnp_hAT PF05699.14 EJP60888.1 - 1.2e-17 63.5 0.1 3.4e-17 62.0 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 EJP60888.1 - 2.4e-06 27.4 0.4 5.5e-06 26.3 0.4 1.6 1 0 0 1 1 1 1 BED zinc finger DUF4379 PF14311.6 EJP60888.1 - 0.014 15.8 0.4 0.043 14.2 0.4 1.9 1 0 0 1 1 1 0 Probable Zinc-ribbon domain DUF4413 PF14372.6 EJP60888.1 - 0.092 13.1 0.0 0.36 11.2 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) DUF3808 PF10300.9 EJP60889.1 - 9e-36 123.6 2.6 3.2e-35 121.8 2.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) DUF601 PF04642.12 EJP60889.1 - 0.027 14.0 0.4 0.041 13.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Inhibitor_I9 PF05922.16 EJP60890.1 - 3.1e-14 53.4 0.6 1.9e-13 50.9 0.1 2.6 2 0 0 2 2 2 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 EJP60891.1 - 5.6e-33 114.5 7.3 7.7e-33 114.0 7.3 1.1 1 0 0 1 1 1 1 Subtilase family DUF1691 PF07950.11 EJP60893.1 - 0.0053 17.5 0.1 0.27 12.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Collagen PF01391.18 EJP60894.1 - 4.1 7.2 13.9 0.46 10.3 8.8 2.0 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Dimer_Tnp_hAT PF05699.14 EJP60895.1 - 9.6e-19 67.0 0.5 2.7e-18 65.6 0.5 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 EJP60895.1 - 0.0022 18.3 0.1 0.01 16.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4413) Biopterin_H PF00351.21 EJP60895.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Sua5_yciO_yrdC PF01300.18 EJP60898.1 - 3.1e-12 46.3 0.0 4.3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Dimer_Tnp_hAT PF05699.14 EJP60899.1 - 6.2e-19 67.6 0.2 2e-18 66.0 0.1 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 EJP60899.1 - 0.0015 18.9 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) zf-BED PF02892.15 EJP60899.1 - 0.012 15.6 0.2 0.012 15.6 0.2 2.1 3 0 0 3 3 3 0 BED zinc finger Fungal_trans_2 PF11951.8 EJP60900.1 - 1.5e-14 53.6 0.1 1.9e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_25 PF13649.6 EJP60901.1 - 1e-14 55.0 0.0 2.8e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP60901.1 - 7.5e-12 45.8 0.0 1.5e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP60901.1 - 4.7e-11 42.7 0.0 3.8e-10 39.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP60901.1 - 2e-10 40.8 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP60901.1 - 3.5e-08 34.1 0.0 1.1e-07 32.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJP60901.1 - 3.6e-05 23.2 0.0 6.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EJP60901.1 - 0.0008 18.9 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EJP60901.1 - 0.016 14.8 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EJP60901.1 - 0.048 12.9 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 EJP60901.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 EJP60901.1 - 0.13 11.7 0.0 0.51 9.8 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain COX4 PF02936.14 EJP60902.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DDE_3 PF13358.6 EJP60903.1 - 3.9e-13 49.4 0.0 6.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 EJP60903.1 - 6.7e-06 25.6 0.1 1.3e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 EJP60903.1 - 0.00056 20.5 0.0 0.002 18.7 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain rve PF00665.26 EJP60903.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain Arg_repressor PF01316.21 EJP60903.1 - 0.035 13.9 0.0 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain DDE_Tnp_ISAZ013 PF07592.11 EJP60903.1 - 0.1 11.5 0.0 2.1 7.3 0.0 2.0 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain Transmemb_17 PF09799.9 EJP60905.1 - 0.042 14.4 0.6 0.12 13.0 0.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein DUF202 PF02656.15 EJP60905.1 - 1.7 9.1 7.5 20 5.7 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase_fungal PF17667.1 EJP60906.1 - 1.4e-126 422.6 0.8 2.1e-126 422.0 0.8 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EJP60906.1 - 1.3e-08 34.5 0.0 2.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EJP60906.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EJP60906.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Abhydrolase_2 PF02230.16 EJP60907.1 - 4.5e-07 29.9 0.0 5.8e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EJP60907.1 - 2.6e-06 27.0 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EJP60907.1 - 0.042 13.4 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EJP60907.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.6 1 1 1 2 2 2 0 Serine aminopeptidase, S33 FA_hydroxylase PF04116.13 EJP60910.1 - 2e-21 76.7 7.5 2e-21 76.7 7.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PUMA PF15826.5 EJP60911.1 - 0.13 12.4 5.5 0.15 12.2 5.5 1.0 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis SAP130_C PF16014.5 EJP60911.1 - 6.1 5.8 7.9 3 6.9 6.0 1.4 1 1 1 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus Ferritin_2 PF13668.6 EJP60912.1 - 1.3e-44 151.7 1.9 2.5e-44 150.8 1.9 1.4 1 0 0 1 1 1 1 Ferritin-like domain WD40 PF00400.32 EJP60913.1 - 4.9e-31 106.3 27.3 1.5e-05 25.6 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP60913.1 - 5.4e-13 49.0 0.2 0.13 12.6 0.1 5.9 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJP60913.1 - 0.016 15.1 0.0 0.66 9.8 0.0 2.6 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 EJP60913.1 - 0.018 13.4 0.0 0.029 12.7 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Exo_endo_phos PF03372.23 EJP60914.1 - 2e-17 63.5 0.0 2.2e-16 60.1 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EJP60914.1 - 9e-10 38.2 7.1 8.7e-06 25.4 2.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EJP60914.1 - 2.1e-08 34.3 5.3 0.00045 20.6 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EJP60914.1 - 0.0075 15.8 0.1 0.017 14.6 0.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 EJP60914.1 - 0.05 14.2 4.2 1.8 9.4 0.3 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat Pertussis_S1 PF02917.14 EJP60917.1 - 2.2e-05 24.3 0.4 4.3e-05 23.4 0.4 1.4 1 0 0 1 1 1 1 Pertussis toxin, subunit 1 Enterotoxin_a PF01375.17 EJP60917.1 - 0.0085 15.7 0.5 0.057 13.0 0.5 2.0 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain TerB_C PF15615.6 EJP60917.1 - 0.062 13.6 0.3 0.1 12.9 0.3 1.2 1 0 0 1 1 1 0 TerB-C domain NACHT PF05729.12 EJP60918.1 - 1.1e-09 38.4 0.0 2.8e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EJP60918.1 - 2.4e-05 24.6 0.1 0.0015 18.8 0.0 3.5 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.6 EJP60918.1 - 0.00017 22.0 0.5 0.0014 19.0 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 EJP60918.1 - 0.0028 18.2 0.0 0.0088 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EJP60918.1 - 0.021 15.2 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 EJP60918.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EJP60918.1 - 0.033 13.9 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EJP60918.1 - 0.034 13.7 0.2 0.65 9.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EJP60918.1 - 0.036 14.6 3.3 5.6 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EJP60918.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EJP60918.1 - 0.048 14.2 0.1 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sec34 PF04136.15 EJP60918.1 - 0.062 13.2 3.7 0.083 12.8 0.0 2.8 3 0 0 3 3 3 0 Sec34-like family Ploopntkinase3 PF18751.1 EJP60918.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 EJP60918.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Laminin_II PF06009.12 EJP60918.1 - 0.099 12.7 6.0 0.26 11.3 0.7 2.7 1 1 1 2 2 2 0 Laminin Domain II AAA_28 PF13521.6 EJP60918.1 - 0.12 12.6 0.0 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 EJP60918.1 - 0.74 9.9 6.2 8.7 6.4 0.1 3.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C2H2 PF00096.26 EJP60919.1 - 0.081 13.4 18.7 0.58 10.7 0.2 5.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type XdhC_C PF13478.6 EJP60919.1 - 0.15 12.6 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Integrin_B_tail PF07965.12 EJP60919.1 - 0.22 12.1 2.7 19 5.9 0.4 2.9 1 1 2 3 3 3 0 Integrin beta tail domain zf-HIT PF04438.16 EJP60919.1 - 0.42 10.5 1.8 5.8 6.9 0.2 2.9 2 0 0 2 2 2 0 HIT zinc finger zf-nanos PF05741.13 EJP60919.1 - 0.49 10.7 6.3 1.4 9.2 0.5 3.4 2 1 1 3 3 3 0 Nanos RNA binding domain zf-C2H2_4 PF13894.6 EJP60919.1 - 0.57 11.2 13.9 9.6 7.4 0.3 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger Aminotran_5 PF00266.19 EJP60920.1 - 7.9e-28 97.5 0.0 4.7e-17 62.0 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V HET PF06985.11 EJP60925.1 - 0.00011 22.6 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COR PF16095.5 EJP60925.1 - 0.0025 17.7 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain AMPK1_CBM PF16561.5 EJP60927.1 - 2.6e-21 75.6 0.7 5.6e-21 74.6 0.7 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EJP60927.1 - 0.00017 21.8 0.2 0.00036 20.8 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 EJP60927.1 - 0.022 15.3 0.7 0.061 13.9 0.7 1.7 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) DUF5305 PF17231.2 EJP60927.1 - 0.14 11.5 1.6 0.39 10.1 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Glyco_hydro_114 PF03537.13 EJP60928.1 - 7.4e-79 264.3 0.3 9.6e-79 263.9 0.3 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Fungal_trans PF04082.18 EJP60929.1 - 5.9e-23 81.3 0.1 9.1e-23 80.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP60929.1 - 4.3e-07 29.9 13.0 7.9e-07 29.1 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 EJP60930.1 - 5.7e-42 143.8 0.0 7.7e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EJP60930.1 - 4.7e-10 39.7 0.0 7.6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.6 EJP60931.1 - 5.3e-48 163.6 0.1 7.5e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP60931.1 - 3e-38 131.2 0.1 4.3e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP60931.1 - 5.3e-09 36.2 1.3 8.5e-09 35.6 1.3 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EJP60931.1 - 0.0032 16.7 0.1 0.0056 15.8 0.1 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RuBisCO_large PF00016.20 EJP60931.1 - 0.15 11.2 0.5 0.23 10.6 0.5 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Hydrolase_6 PF13344.6 EJP60932.1 - 1.8e-23 82.6 0.0 3.8e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP60932.1 - 5.6e-13 48.8 0.0 3.4e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EJP60932.1 - 0.033 14.5 0.0 22 5.3 0.0 3.3 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase COX6C PF02937.15 EJP60934.1 - 0.025 14.7 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc XylR_N PF06505.11 EJP60934.1 - 0.029 14.1 0.0 0.029 14.1 0.0 1.0 1 0 0 1 1 1 0 Activator of aromatic catabolism Ribosomal_L22 PF00237.19 EJP60935.1 - 7.8e-18 64.6 0.0 1.5e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF5119 PF17145.4 EJP60935.1 - 0.0044 17.0 0.2 0.0065 16.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5119) SKG6 PF08693.10 EJP60936.1 - 0.0035 16.7 5.3 0.0085 15.5 5.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 EJP60936.1 - 0.062 13.2 0.6 0.12 12.3 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4448 PF14610.6 EJP60936.1 - 0.068 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RIFIN PF02009.16 EJP60936.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 EJP60936.1 - 0.15 13.0 0.0 0.35 11.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ndc1_Nup PF09531.10 EJP60936.1 - 3.5 6.2 11.1 4.9 5.7 11.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 EJP60936.1 - 4.3 6.1 5.3 5.5 5.7 5.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 EJP60936.1 - 4.8 6.3 27.3 6.9 5.7 27.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Podoplanin PF05808.11 EJP60936.1 - 7.6 6.6 14.1 15 5.6 14.0 1.6 1 1 0 1 1 1 0 Podoplanin RRM_1 PF00076.22 EJP60937.1 - 5.2e-49 164.0 0.1 4e-18 65.0 0.2 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJP60937.1 - 4.9e-34 116.0 0.0 1.1e-26 92.5 0.0 4.1 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EJP60937.1 - 1.7e-10 40.7 0.0 0.0031 17.5 0.0 3.7 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EJP60937.1 - 1.6e-09 37.4 0.0 0.00016 21.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EJP60937.1 - 0.00049 20.0 0.0 0.16 12.0 0.0 3.4 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EJP60937.1 - 0.0092 16.0 0.5 0.35 10.9 0.1 3.4 3 0 0 3 3 3 1 RNA binding motif RRM_Rrp7 PF17799.1 EJP60937.1 - 0.023 14.5 0.3 0.18 11.6 0.1 2.6 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain TPR_14 PF13428.6 EJP60937.1 - 0.11 13.4 0.0 21 6.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HA2 PF04408.23 EJP60938.1 - 2.4e-14 53.5 0.0 7e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EJP60938.1 - 2.3e-13 50.5 0.0 5.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP60938.1 - 1.4e-11 44.5 0.0 3.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EJP60938.1 - 1e-07 32.2 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EJP60938.1 - 8.3e-07 29.4 0.1 3.3e-06 27.4 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP60938.1 - 0.02 15.3 0.2 0.057 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EJP60938.1 - 0.074 13.0 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Sugar_tr PF00083.24 EJP60939.1 - 8.4e-25 87.5 23.7 4.3e-16 58.8 7.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3611 PF12263.8 EJP60939.1 - 0.56 10.1 6.0 0.06 13.3 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Yippee-Mis18 PF03226.14 EJP60942.1 - 6.8e-17 61.6 1.4 7.7e-17 61.4 1.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EJP60942.1 - 0.0026 18.0 2.5 0.0035 17.5 2.5 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 EJP60942.1 - 0.0082 16.5 2.6 0.016 15.6 0.3 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Nuc_sug_transp PF04142.15 EJP60943.1 - 3.9e-07 29.5 0.1 6.9e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EJP60943.1 - 3.1e-06 27.4 29.1 0.0002 21.5 3.4 2.7 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 EJP60943.1 - 0.0025 17.2 0.2 0.0025 17.2 0.2 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family GARS_A PF01071.19 EJP60944.1 - 7e-84 280.4 0.0 1.1e-83 279.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EJP60944.1 - 8.5e-36 122.6 0.0 8.6e-35 119.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EJP60944.1 - 8.5e-33 113.7 0.0 2.7e-32 112.0 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EJP60944.1 - 2.6e-26 91.7 0.4 9.7e-25 86.7 0.1 2.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EJP60944.1 - 1.7e-14 54.2 2.6 5.1e-14 52.7 2.6 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 EJP60944.1 - 0.00052 19.6 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EJP60944.1 - 0.0014 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EJP60944.1 - 0.008 16.2 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 EJP60944.1 - 0.012 15.2 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 EJP60944.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 EJP60944.1 - 0.084 12.1 0.1 0.27 10.5 0.1 1.8 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RimK PF08443.11 EJP60944.1 - 0.14 11.7 0.4 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CHAP PF05257.16 EJP60945.1 - 1.7e-11 44.5 1.6 3.4e-11 43.6 1.6 1.5 1 0 0 1 1 1 1 CHAP domain Dimer_Tnp_hAT PF05699.14 EJP60947.1 - 2e-15 56.3 0.1 4.2e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 EJP60947.1 - 0.087 12.9 0.3 0.25 11.4 0.3 1.8 1 1 0 1 1 1 0 BED zinc finger Dynein_light PF01221.18 EJP60947.1 - 0.17 12.2 0.0 18 5.7 0.0 2.7 2 0 0 2 2 2 0 Dynein light chain type 1 bZIP_1 PF00170.21 EJP60948.1 - 1.4e-08 34.7 8.7 2.5e-08 33.9 8.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EJP60948.1 - 0.00052 20.0 9.5 0.0014 18.7 9.5 1.8 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EJP60948.1 - 0.0062 17.0 4.9 0.0062 17.0 4.9 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor MDFI PF15316.6 EJP60948.1 - 0.11 12.6 3.0 0.17 12.0 3.0 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Caskin-Pro-rich PF16907.5 EJP60948.1 - 1.4 9.5 6.3 0.23 12.0 1.0 2.0 2 0 0 2 2 2 0 Proline rich region of Caskin proteins PGBA_C PF15437.6 EJP60948.1 - 2.8 8.3 9.9 4 7.9 9.4 1.5 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal UPF0449 PF15136.6 EJP60948.1 - 7.7 7.1 7.1 1.8 9.1 1.9 2.1 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 ATP-synt_ab_N PF02874.23 EJP60949.1 - 1.4e-19 70.3 0.4 4.3e-19 68.8 0.3 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 EJP60949.1 - 7.1e-15 55.2 0.1 2.4e-14 53.5 0.1 1.8 1 1 1 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 EJP60949.1 - 0.0088 15.9 0.9 0.037 13.9 0.9 1.9 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain Ank_2 PF12796.7 EJP60950.1 - 7.6e-69 228.3 0.0 1.2e-15 57.9 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP60950.1 - 1.5e-56 187.7 13.0 2.7e-10 40.3 0.4 8.0 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EJP60950.1 - 2.3e-49 165.1 3.8 4.9e-09 36.6 0.0 7.6 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EJP60950.1 - 5.4e-47 156.3 2.2 6.3e-05 23.2 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 EJP60950.1 - 8.3e-33 108.7 0.4 0.002 18.5 0.0 9.6 10 0 0 10 10 10 6 Ankyrin repeat DUF3734 PF12536.8 EJP60950.1 - 4.1e-05 23.9 1.6 0.97 9.8 0.2 4.1 2 2 2 4 4 4 2 Patatin phospholipase DUF4913 PF16259.5 EJP60950.1 - 0.0038 17.3 0.4 4.5 7.4 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4913) DUF2007 PF09413.10 EJP60950.1 - 0.0078 16.3 0.0 2.4 8.4 0.0 3.3 3 0 0 3 3 3 1 Putative prokaryotic signal transducing protein YbjN PF10722.9 EJP60950.1 - 0.028 14.5 1.4 29 4.7 0.1 3.9 2 1 2 4 4 4 0 Putative bacterial sensory transduction regulator VWA_3_C PF18571.1 EJP60950.1 - 0.061 13.2 0.8 25 4.8 0.0 4.1 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain PRODH PF18327.1 EJP60950.1 - 0.31 11.3 3.2 66 3.8 0.2 4.0 4 0 0 4 4 4 0 Proline utilization A proline dehydrogenase N-terminal domain AMP-binding PF00501.28 EJP60951.1 - 4.8e-138 460.3 0.2 2.9e-77 260.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EJP60951.1 - 1.8e-46 158.8 0.0 4.4e-20 71.8 0.0 3.5 2 1 1 3 3 3 3 Condensation domain PP-binding PF00550.25 EJP60951.1 - 8.3e-29 99.7 1.3 1.2e-13 51.2 0.1 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP60951.1 - 7.3e-07 30.1 0.1 0.0043 18.0 0.1 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Cyclophil_like2 PF18050.1 EJP60951.1 - 0.00088 19.2 0.0 0.37 10.8 0.0 2.6 2 0 0 2 2 2 2 Cyclophilin-like family BCNT PF07572.12 EJP60951.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Bucentaur or craniofacial development DUF547 PF04784.14 EJP60951.1 - 0.2 11.7 0.0 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF547 PRP4 PF08799.11 EJP60951.1 - 1 8.9 3.9 8.8 6.0 0.2 2.6 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like DUF3435 PF11917.8 EJP60952.1 - 6.1e-10 38.6 0.6 4.3e-09 35.8 0.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3435) Myb_DNA-bind_6 PF13921.6 EJP60952.1 - 0.071 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain RMF PF04957.12 EJP60952.1 - 0.12 12.6 0.0 19 5.6 0.0 2.7 2 0 0 2 2 2 0 Ribosome modulation factor DUF3338 PF11819.8 EJP60952.1 - 0.43 10.6 5.8 1.4 8.9 2.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) Patatin PF01734.22 EJP60953.1 - 7.3e-05 23.0 0.1 0.00033 20.9 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Prok-RING_4 PF14447.6 EJP60953.1 - 0.029 14.2 9.3 0.084 12.8 9.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EJP60953.1 - 2.2 8.3 10.8 4.7 7.3 10.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EJP60953.1 - 9.2 6.2 12.0 24 4.9 12.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FMO-like PF00743.19 EJP60954.1 - 4.9e-10 38.4 0.0 6e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP60954.1 - 3.1e-06 26.7 0.0 3.6e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP60954.1 - 0.00028 20.1 0.1 0.0003 20.0 0.1 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Ferric_reduct PF01794.19 EJP60955.1 - 0.012 15.8 4.9 0.012 15.8 4.9 2.4 2 1 0 2 2 2 0 Ferric reductase like transmembrane component RVT_1 PF00078.27 EJP60957.1 - 8.2e-35 120.3 0.0 1.7e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EJP60957.1 - 2.9e-21 75.5 0.3 1.3e-20 73.4 0.3 2.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EJP60957.1 - 1.6e-10 40.9 0.4 1.6e-10 40.9 0.4 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-C2H2 PF00096.26 EJP60957.1 - 0.0027 18.1 0.3 0.0027 18.1 0.3 2.9 3 0 0 3 3 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP60957.1 - 0.036 14.9 0.3 0.036 14.9 0.3 3.1 2 0 0 2 2 1 0 C2H2-type zinc finger Glyco_hydro_71 PF03659.14 EJP60957.1 - 0.12 11.2 4.6 1.1 8.0 0.6 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 71 Thioredoxin_3 PF13192.6 EJP60957.1 - 0.25 11.4 4.7 39 4.4 0.1 4.0 3 0 0 3 3 3 0 Thioredoxin domain NAD-GH PF10712.9 EJP60957.1 - 0.64 8.4 6.2 1 7.8 0.7 2.1 2 0 0 2 2 2 0 NAD-specific glutamate dehydrogenase HTH_Tnp_1 PF01527.20 EJP60957.1 - 1.2 9.5 5.0 11 6.4 0.4 2.9 2 0 0 2 2 2 0 Transposase Dscam_C PF12355.8 EJP60957.1 - 2.1 9.3 14.4 1.2 10.1 0.1 3.9 4 0 0 4 4 4 0 Down syndrome cell adhesion molecule C terminal DUF4832 PF16116.5 EJP60957.1 - 4.9 6.9 8.2 11 5.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4832) Mo25 PF08569.11 EJP60959.1 - 3.6e-119 398.0 0.0 6.9e-119 397.0 0.0 1.4 1 1 0 1 1 1 1 Mo25-like Sec7_N PF12783.7 EJP60959.1 - 0.051 13.5 0.1 1.1 9.1 0.0 2.9 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SWIB PF02201.18 EJP60960.1 - 3e-05 23.8 0.0 9.1e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain Pkinase PF00069.25 EJP60961.1 - 9.8e-70 234.9 0.0 1.4e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP60961.1 - 1.6e-35 122.6 0.0 5.5e-35 120.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP60961.1 - 2.1e-05 24.0 0.1 0.0074 15.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 EJP60961.1 - 0.00032 19.8 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EJP60961.1 - 0.0074 15.7 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP60961.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EJP60961.1 - 0.052 13.2 0.4 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rav1p_C PF12234.8 EJP60962.1 - 2.3e-273 908.4 0.0 4.2e-273 907.6 0.0 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal OPT PF03169.15 EJP60962.1 - 3.9e-119 399.0 22.0 1.3e-72 245.4 0.6 2.2 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Sfi1 PF08457.10 EJP60962.1 - 1e-20 73.9 74.7 1.5e-14 53.5 31.1 2.2 1 1 1 2 2 2 2 Sfi1 spindle body protein Transgly_assoc PF04226.13 EJP60962.1 - 0.058 13.7 1.3 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 Transglycosylase associated protein Methyltransf_25 PF13649.6 EJP60963.1 - 9.4e-12 45.5 0.0 2.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EJP60963.1 - 7e-10 38.8 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EJP60963.1 - 1.6e-09 38.2 0.0 4.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP60963.1 - 1.3e-08 34.7 0.0 2.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP60963.1 - 5.2e-06 26.4 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJP60963.1 - 1.2e-05 24.7 0.0 5.6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EJP60963.1 - 3.1e-05 23.9 0.1 6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP60963.1 - 0.00021 20.9 0.2 0.00037 20.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EJP60963.1 - 0.00081 20.1 0.0 0.0019 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EJP60963.1 - 0.0086 15.8 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 EJP60963.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EJP60963.1 - 0.027 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EJP60963.1 - 0.03 13.5 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 EJP60963.1 - 0.061 12.2 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) UPF0020 PF01170.18 EJP60963.1 - 0.071 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Uso1_p115_head PF04869.14 EJP60964.1 - 1.9e-107 359.0 0.6 1.9e-107 359.0 0.6 2.2 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EJP60964.1 - 8.4e-14 52.0 29.8 8.4e-14 52.0 29.8 3.6 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Pox_A_type_inc PF04508.12 EJP60964.1 - 0.82 9.6 7.0 1.3 9.0 1.0 3.9 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat XRN_M PF17846.1 EJP60965.1 - 1.4e-139 465.9 0.1 5e-139 464.1 0.0 1.9 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EJP60965.1 - 1.8e-99 332.0 0.0 3.1e-99 331.3 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_3 PF13917.6 EJP60965.1 - 0.25 11.4 1.5 0.48 10.4 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EJP60965.1 - 0.26 11.2 2.4 0.66 9.8 2.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Sulfatase PF00884.23 EJP60966.1 - 2.3e-19 69.9 0.0 4.3e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EJP60966.1 - 0.003 17.8 0.2 0.0047 17.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) EcKinase PF02958.20 EJP60967.1 - 3.2e-13 49.7 0.0 9.3e-13 48.1 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 EJP60967.1 - 5.9e-10 39.5 0.0 1.4e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EJP60967.1 - 9.1e-05 21.5 0.0 0.00016 20.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EJP60967.1 - 0.00036 20.2 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Glyco_hydro_18 PF00704.28 EJP60968.1 - 5.2e-13 49.4 0.1 9.2e-13 48.6 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 FixQ PF05545.11 EJP60969.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ CCCAP PF15964.5 EJP60970.1 - 0.00011 20.7 1.9 0.00017 20.0 1.9 1.3 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family AWS PF17907.1 EJP60970.1 - 0.00059 19.8 8.0 0.0014 18.7 8.0 1.6 1 0 0 1 1 1 1 AWS domain KASH_CCD PF14662.6 EJP60970.1 - 0.0057 16.5 6.9 0.0095 15.8 6.9 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH NINJA_B PF16136.5 EJP60970.1 - 0.0088 16.4 1.3 0.025 14.9 1.3 1.7 1 0 0 1 1 1 1 Putative nuclear localisation signal Rx_N PF18052.1 EJP60970.1 - 0.061 13.6 3.2 0.14 12.4 3.2 1.6 1 0 0 1 1 1 0 Rx N-terminal domain SET PF00856.28 EJP60970.1 - 0.072 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 SET domain Cnn_1N PF07989.11 EJP60970.1 - 0.075 13.2 7.9 0.3 11.3 7.9 2.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 CENP-H PF05837.12 EJP60970.1 - 0.11 12.9 6.0 0.34 11.3 6.0 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 EJP60970.1 - 0.19 11.5 6.2 0.35 10.7 5.2 2.0 1 1 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 EJP60970.1 - 0.3 11.4 7.4 0.091 13.0 2.7 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 EJP60970.1 - 0.33 11.1 5.4 0.98 9.6 1.5 3.0 2 1 1 3 3 3 0 bZIP transcription factor Lectin_N PF03954.14 EJP60970.1 - 0.87 9.3 9.1 2.6 7.8 0.2 2.8 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain YabA PF06156.13 EJP60970.1 - 0.88 10.2 7.2 2.3 8.9 7.0 1.9 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 EJP60970.1 - 4.8 7.7 18.6 52 4.4 14.6 3.2 2 1 0 2 2 2 0 Cell division protein ZapB FAD_binding_3 PF01494.19 EJP60971.1 - 7e-07 28.8 0.1 0.38 10.0 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EJP60971.1 - 1.9e-06 28.0 0.0 5.5e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EJP60971.1 - 0.00061 19.7 0.0 0.00079 19.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EJP60971.1 - 0.0027 16.5 0.1 0.0037 16.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EJP60971.1 - 0.0049 16.2 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP60971.1 - 0.0053 16.4 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EJP60971.1 - 0.038 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EJP60971.1 - 0.087 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EJP60971.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain XdhC_C PF13478.6 EJP60971.1 - 0.19 12.2 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain FAD_oxidored PF12831.7 EJP60971.1 - 0.21 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Patatin PF01734.22 EJP60972.1 - 1.4e-20 74.4 0.1 4.9e-20 72.6 0.1 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase NB-ARC PF00931.22 EJP60972.1 - 1.1e-05 24.8 0.0 2.9e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EJP60972.1 - 3e-05 24.3 0.0 0.00011 22.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP60972.1 - 8.5e-05 23.0 3.6 0.00099 19.5 3.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 EJP60972.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Organ_specific PF10950.8 EJP60973.1 - 0.091 13.5 1.5 0.55 10.9 0.1 2.3 2 0 0 2 2 2 0 Organ specific protein F-box-like PF12937.7 EJP60974.1 - 0.017 15.0 1.4 0.043 13.7 1.4 1.7 1 1 0 1 1 1 0 F-box-like DUF3723 PF12520.8 EJP60975.1 - 1.2e-166 555.4 0.0 1.4e-166 555.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DUF2507 PF10702.9 EJP60975.1 - 0.091 12.7 0.1 9.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2507) CENP-K PF11802.8 EJP60975.1 - 0.16 11.5 2.7 0.26 10.8 2.7 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF3723 PF12520.8 EJP60976.1 - 5.8e-160 533.3 0.4 1.7e-159 531.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) Pkinase PF00069.25 EJP60977.1 - 1.3e-07 31.3 0.4 4.9e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP60977.1 - 0.00042 19.7 0.1 0.00056 19.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP60977.1 - 0.045 13.1 0.0 0.079 12.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Dynamin_M PF01031.20 EJP60978.1 - 0.0002 20.7 0.0 0.00033 20.0 0.0 1.3 1 1 0 1 1 1 1 Dynamin central region PP_M1 PF03012.14 EJP60980.1 - 0.15 11.6 0.2 0.22 11.0 0.2 1.2 1 0 0 1 1 1 0 Phosphoprotein DDE_3 PF13358.6 EJP60981.1 - 2.7e-13 49.9 0.0 4.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 EJP60981.1 - 0.0093 16.1 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 EJP60982.1 - 2.7e-23 82.4 0.0 4.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 EJP60982.1 - 6.1e-07 29.0 0.1 1.4e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 EJP60982.1 - 0.0045 17.2 0.3 0.031 14.5 0.1 2.2 2 0 0 2 2 2 1 Transposase rve PF00665.26 EJP60982.1 - 0.0086 16.3 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 EJP60982.1 - 0.021 15.4 1.4 0.041 14.5 0.0 2.2 3 0 0 3 3 3 0 Homeodomain-like domain Linker_histone PF00538.19 EJP60982.1 - 0.092 13.1 0.0 0.34 11.3 0.0 2.0 2 0 0 2 2 2 0 linker histone H1 and H5 family NPH3 PF03000.14 EJP60982.1 - 0.16 11.6 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 NPH3 family RVT_1 PF00078.27 EJP60984.1 - 2.3e-38 131.9 0.0 3e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 EJP60985.1 - 8.2e-30 103.9 19.2 8.2e-30 103.9 19.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP60985.1 - 5e-08 32.2 6.2 5e-08 32.2 6.2 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.24 EJP60986.1 - 2.9e-71 240.7 17.2 4.2e-71 240.1 17.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP60986.1 - 1.3e-14 53.9 32.4 4.1e-13 49.0 11.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF2157 PF09925.9 EJP60986.1 - 0.16 11.8 4.8 0.67 9.7 4.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Conotoxin PF02950.17 EJP60987.1 - 0.11 13.5 4.0 0.11 13.5 4.0 2.4 2 1 0 2 2 2 0 Conotoxin Dickkopf_N PF04706.12 EJP60987.1 - 0.36 11.4 20.8 1.4 9.5 5.5 3.1 1 1 2 3 3 3 0 Dickkopf N-terminal cysteine-rich region Prokineticin PF06607.11 EJP60987.1 - 0.99 9.8 11.3 0.22 11.9 2.8 2.4 1 1 1 2 2 2 0 Prokineticin Toxin_12 PF07740.12 EJP60987.1 - 1.5 9.6 19.9 0.26 12.0 5.7 3.3 3 0 0 3 3 3 0 Ion channel inhibitory toxin Het-C PF07217.11 EJP60988.1 - 8.2e-152 506.6 0.0 1.1e-151 506.2 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Peptidase_M20 PF01546.28 EJP60989.1 - 3.4e-07 30.2 0.1 5.2e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJP60989.1 - 4e-06 26.7 0.0 9.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Glyco_hydro_20 PF00728.22 EJP60990.1 - 7e-96 321.7 0.8 9.1e-96 321.3 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EJP60990.1 - 1.1e-31 110.4 0.1 2.2e-31 109.3 0.1 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EJP60990.1 - 0.00016 22.4 0.0 0.00041 21.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 CW_7 PF08230.11 EJP60990.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 CW_7 repeat AA_permease PF00324.21 EJP60991.1 - 3.5e-144 481.0 44.4 4e-144 480.8 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP60991.1 - 5.4e-39 134.2 46.1 6.9e-39 133.9 46.1 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_3 PF13302.7 EJP60992.1 - 3.7e-13 50.4 0.0 4.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJP60992.1 - 0.0024 18.0 0.0 0.0034 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP60992.1 - 0.032 14.5 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Zn-ribbon_8 PF09723.10 EJP60993.1 - 0.84 9.8 8.3 0.53 10.4 0.4 2.7 2 0 0 2 2 2 0 Zinc ribbon domain TMEM51 PF15345.6 EJP60994.1 - 0.021 14.7 0.4 0.029 14.2 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Podoplanin PF05808.11 EJP60994.1 - 0.027 14.6 0.2 0.042 14.0 0.2 1.3 1 0 0 1 1 1 0 Podoplanin Tautomerase_3 PF14832.6 EJP60995.1 - 6e-12 46.0 0.2 1.1e-11 45.1 0.2 1.4 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 EJP60995.1 - 0.15 12.0 0.3 1 9.3 0.1 2.3 2 1 0 2 2 2 0 Tautomerase enzyme MFS_1 PF07690.16 EJP60996.1 - 1e-33 116.7 30.4 5.2e-33 114.4 30.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 EJP60996.1 - 0.5 10.7 14.0 1.2 9.4 1.2 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Amino_oxidase PF01593.24 EJP60998.1 - 6.6e-64 216.9 0.3 6.3e-63 213.6 0.3 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP60998.1 - 3.8e-10 39.9 0.1 1.1e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP60998.1 - 0.0024 17.2 0.0 0.09 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP60998.1 - 0.0031 16.8 0.4 0.022 14.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP60998.1 - 0.0052 16.4 3.8 0.13 11.8 0.1 3.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP60998.1 - 0.0071 16.9 0.1 1.7 9.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP60998.1 - 0.04 13.2 0.1 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 EJP60998.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MtrD PF04207.12 EJP60998.1 - 0.34 10.6 3.6 0.6 9.8 3.6 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D AA_permease_2 PF13520.6 EJP60999.1 - 9.5e-49 166.4 37.7 1.2e-48 166.0 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP60999.1 - 2.6e-13 49.4 32.5 3.8e-13 48.8 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease Adap_comp_sub PF00928.21 EJP61000.1 - 7.4e-83 277.9 0.0 9.4e-83 277.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EJP61000.1 - 3.1e-05 24.0 0.2 5.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PLDc_2 PF13091.6 EJP61001.1 - 3.7e-18 65.7 0.0 2.1e-12 47.1 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EJP61001.1 - 0.0041 17.2 0.3 0.11 12.8 0.2 2.4 2 0 0 2 2 2 1 Phospholipase D Active site motif DSBA PF01323.20 EJP61002.1 - 1.2e-33 116.6 0.0 1.3e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EJP61002.1 - 3.8e-06 27.2 0.3 2.1e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 EJP61002.1 - 0.0093 16.0 0.0 0.34 11.0 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin domain Peptidase_S8 PF00082.22 EJP61004.1 - 7.6e-21 74.6 0.0 1.6e-20 73.6 0.0 1.4 1 1 0 1 1 1 1 Subtilase family HlyIII PF03006.20 EJP61005.1 - 1.5e-41 142.5 23.0 2e-41 142.2 23.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF998 PF06197.13 EJP61005.1 - 2.4 7.7 15.4 6.8 6.2 3.7 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF998) Zn_clus PF00172.18 EJP61006.1 - 2e-07 31.0 9.2 4.4e-07 29.9 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dimer_Tnp_hAT PF05699.14 EJP61009.1 - 9.3e-19 67.0 0.1 2.3e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Zn_clus PF00172.18 EJP61011.1 - 3.3e-09 36.7 12.6 6.9e-09 35.7 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP61011.1 - 0.06 12.4 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP61012.1 - 8.9e-06 25.7 17.4 8.9e-06 25.7 17.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LcrV PF04792.12 EJP61014.1 - 0.03 13.6 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 V antigen (LcrV) protein ANAPC4_WD40 PF12894.7 EJP61015.1 - 0.0016 18.7 0.0 0.53 10.6 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJP61015.1 - 0.0062 17.4 2.6 0.75 10.8 0.0 4.1 5 1 0 5 5 5 1 WD domain, G-beta repeat Lactonase PF10282.9 EJP61015.1 - 0.21 10.8 0.0 4.4 6.5 0.0 2.6 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller DSPc PF00782.20 EJP61016.1 - 2.9e-26 91.9 0.0 3.8e-20 72.0 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJP61016.1 - 0.0035 17.0 0.1 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DEAD_2 PF06733.15 EJP61017.1 - 1.1e-55 188.0 0.4 1.1e-55 188.0 0.4 1.6 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 EJP61017.1 - 3.9e-43 147.6 0.0 1.5e-42 145.6 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 EJP61017.1 - 2.6e-42 144.7 0.4 2.2e-38 131.9 0.1 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EJP61017.1 - 0.0014 18.7 0.1 0.043 13.8 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EJP61017.1 - 0.0036 16.1 0.1 0.05 12.3 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DDHD PF02862.17 EJP61018.1 - 2.5e-19 70.3 11.0 4e-19 69.7 0.0 3.7 2 2 0 2 2 2 1 DDHD domain LIDHydrolase PF10230.9 EJP61018.1 - 0.044 13.3 0.0 0.52 9.8 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 EJP61018.1 - 0.083 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EJP61018.1 - 0.1 12.4 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase PRP3 PF08572.10 EJP61019.1 - 6e-72 242.0 5.3 8.8e-72 241.4 5.3 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EJP61019.1 - 4.7e-47 159.8 0.2 4.7e-47 159.8 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Histone PF00125.24 EJP61020.1 - 4e-52 176.0 1.9 4.5e-52 175.9 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EJP61020.1 - 4.1e-06 27.1 0.0 6.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EJP61020.1 - 3.3e-05 24.5 1.0 3.9e-05 24.3 1.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EJP61020.1 - 5.4e-05 23.3 0.2 0.0001 22.4 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EJP61020.1 - 0.0017 18.6 0.2 0.0033 17.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EJP61020.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 EJP61020.1 - 0.055 13.5 0.1 0.095 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EJP61021.1 - 2.9e-09 37.0 0.1 3.5e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EJP61021.1 - 9.2e-06 26.0 0.2 1.1e-05 25.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EJP61021.1 - 3.3e-05 24.0 0.1 4.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EJP61021.1 - 5.7e-05 23.3 0.1 9.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EJP61021.1 - 0.00028 21.2 0.1 0.00048 20.4 0.1 1.5 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EJP61021.1 - 0.0033 17.5 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit HIGH_NTase1_ass PF16581.5 EJP61021.1 - 0.028 14.4 0.0 0.032 14.2 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Bromo_TP PF07524.13 EJP61021.1 - 0.04 13.9 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Ribosomal_S17e PF00833.18 EJP61021.1 - 0.1 12.5 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal S17 zf-C2H2 PF00096.26 EJP61022.1 - 4.5e-09 36.3 16.1 0.0057 17.0 1.0 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP61022.1 - 2.2e-05 24.9 8.9 0.73 10.8 1.0 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger EPSP_synthase PF00275.20 EJP61023.1 - 8.6e-127 423.3 0.0 1.5e-126 422.5 0.0 1.4 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EJP61023.1 - 1e-102 342.8 0.0 2.1e-102 341.8 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EJP61023.1 - 1.4e-57 195.6 0.0 2.3e-57 194.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EJP61023.1 - 2.7e-41 141.3 0.0 8e-40 136.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EJP61023.1 - 1.1e-23 83.2 0.0 2.9e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EJP61023.1 - 7.1e-08 32.5 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EJP61023.1 - 7.1e-08 32.6 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 EJP61023.1 - 0.00029 20.6 0.2 0.00061 19.5 0.2 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain AAA_33 PF13671.6 EJP61023.1 - 0.086 13.0 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RasGAP PF00616.19 EJP61024.1 - 8.4e-18 64.8 0.0 4.7e-13 49.3 0.0 3.6 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EJP61024.1 - 2.9e-07 30.7 0.2 7.9e-07 29.3 0.2 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TetR_C_22 PF17928.1 EJP61024.1 - 0.0079 16.5 0.2 0.033 14.5 0.2 2.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NopRA1 PF16201.5 EJP61024.1 - 0.33 10.5 2.7 8.1 6.0 0.1 3.4 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 RRM_1 PF00076.22 EJP61025.1 - 8.3e-53 176.1 0.0 6.2e-17 61.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EJP61025.1 - 8.8e-07 28.9 0.0 0.33 11.0 0.0 4.1 3 2 0 3 3 3 2 Limkain b1 RRM_5 PF13893.6 EJP61025.1 - 7.6e-06 25.5 0.0 0.0071 15.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJP61025.1 - 0.00048 19.9 0.0 5.8 6.8 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EJP61025.1 - 0.00067 19.7 0.0 3.7 7.6 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.10 EJP61025.1 - 0.00087 18.9 0.0 0.083 12.4 0.0 3.0 3 0 0 3 3 3 1 ATP-grasp domain PknH_C PF14032.6 EJP61025.1 - 0.0097 15.8 0.1 17 5.2 0.0 3.2 3 0 0 3 3 3 1 PknH-like extracellular domain RRM_Rrp7 PF17799.1 EJP61025.1 - 0.027 14.3 0.0 13 5.5 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain DbpA PF03880.15 EJP61025.1 - 0.15 12.1 0.0 69 3.5 0.0 3.3 3 0 0 3 3 3 0 DbpA RNA binding domain ClpS PF02617.17 EJP61025.1 - 0.18 11.6 0.1 14 5.6 0.1 2.5 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS SRP14 PF02290.15 EJP61026.1 - 6.8e-29 100.1 0.0 6.8e-29 100.1 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein MIF4G PF02854.19 EJP61027.1 - 1e-19 71.0 0.2 2.9e-19 69.6 0.1 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 EJP61027.1 - 9e-15 54.6 0.1 4.5e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 MA3 domain APOBEC_C PF05240.14 EJP61027.1 - 0.088 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Pyr_redox_2 PF07992.14 EJP61028.1 - 6.2e-66 222.6 2.9 8.2e-66 222.2 2.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EJP61028.1 - 5.2e-40 136.1 0.0 1.6e-39 134.5 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EJP61028.1 - 5.9e-24 84.4 8.2 1e-20 74.1 0.3 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP61028.1 - 2.1e-11 43.9 2.6 1.4e-06 28.4 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EJP61028.1 - 5.5e-10 38.9 7.9 5.7e-08 32.2 3.7 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EJP61028.1 - 5.5e-10 39.2 7.7 6.1e-09 35.7 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP61028.1 - 1.1e-08 34.7 8.1 4.7e-07 29.2 2.3 3.0 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 EJP61028.1 - 6.9e-07 28.8 2.1 0.025 13.9 0.3 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EJP61028.1 - 1.1e-06 28.2 3.7 0.0019 17.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP61028.1 - 2.9e-06 26.3 12.3 7.1e-05 21.7 1.6 4.0 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 EJP61028.1 - 4.9e-06 26.0 2.0 0.00047 19.5 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EJP61028.1 - 8.1e-06 25.3 4.0 0.015 14.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EJP61028.1 - 8.7e-06 25.5 11.2 0.0044 16.6 0.4 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP61028.1 - 0.00038 19.6 3.5 0.01 14.9 0.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 EJP61028.1 - 0.0005 19.3 0.5 0.13 11.4 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EJP61028.1 - 0.016 15.6 2.2 2 8.9 0.0 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 EJP61028.1 - 0.076 11.9 5.1 0.14 11.0 0.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FMO-like PF00743.19 EJP61028.1 - 0.11 10.9 0.1 0.17 10.2 0.1 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 EJP61028.1 - 0.21 11.5 4.8 0.26 11.1 0.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FA_desaturase PF00487.24 EJP61029.1 - 4.8e-28 98.7 22.9 7.9e-28 98.0 22.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EJP61029.1 - 1.5e-10 41.1 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Vac14_Fig4_bd PF11916.8 EJP61030.1 - 1.2e-79 266.1 6.1 3.1e-79 264.8 6.1 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EJP61030.1 - 7.3e-19 68.2 0.2 6.5e-10 39.5 0.0 5.1 4 1 1 5 5 5 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EJP61030.1 - 3.7e-05 24.1 11.6 0.67 10.5 0.1 5.2 5 0 0 5 5 5 3 HEAT-like repeat Cnd1 PF12717.7 EJP61030.1 - 0.00084 19.4 0.3 0.076 13.1 0.2 2.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EJP61030.1 - 0.0011 19.0 0.1 1 9.8 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat Dynein_C PF18199.1 EJP61031.1 - 0.15 11.3 0.4 0.2 10.8 0.4 1.3 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain DnaJ PF00226.31 EJP61032.1 - 2.7e-20 72.3 2.2 2.7e-20 72.3 2.2 2.6 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 EJP61032.1 - 2.9e-15 55.3 0.3 0.0052 16.6 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EJP61032.1 - 1.7e-13 49.5 4.9 0.0095 16.0 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EJP61032.1 - 3.3e-09 36.8 4.4 0.15 12.9 0.1 6.7 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJP61032.1 - 1.5e-08 34.7 0.0 0.041 14.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP61032.1 - 8.1e-08 31.9 1.8 0.24 11.7 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP61032.1 - 8.8e-07 29.3 4.3 0.2 12.2 0.0 4.4 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EJP61032.1 - 9.4e-07 28.8 1.4 0.0055 17.0 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJP61032.1 - 2e-06 27.4 0.0 0.082 12.6 0.2 4.3 3 1 1 4 4 4 2 TPR repeat TPR_7 PF13176.6 EJP61032.1 - 4.2e-06 26.4 1.6 0.029 14.4 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EJP61032.1 - 2.4e-05 24.7 3.4 12 6.8 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP61032.1 - 2.5e-05 24.8 2.7 0.62 10.8 0.1 5.0 4 1 1 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP61032.1 - 0.00054 20.1 3.9 2.4 8.4 0.0 4.2 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EJP61032.1 - 0.52 10.6 8.5 27 5.1 0.1 4.9 3 2 0 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 EJP61033.1 - 4.1e-67 222.2 6.3 3e-22 78.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3082 PF11282.8 EJP61033.1 - 0.14 12.4 1.3 0.71 10.2 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3082) APG9 PF04109.16 EJP61034.1 - 2.2e-195 650.3 12.8 2.5e-195 650.0 12.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.11 EJP61035.1 - 2.1e-181 604.4 0.3 2.9e-181 603.9 0.3 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 AAA PF00004.29 EJP61035.1 - 1.2e-37 129.3 0.0 3.3e-37 127.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EJP61035.1 - 1.4e-07 31.4 1.7 8.9e-07 28.8 0.0 3.2 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EJP61035.1 - 5.4e-07 29.3 0.0 1.6e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EJP61035.1 - 5.1e-05 23.6 0.9 0.0015 18.8 0.1 3.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EJP61035.1 - 0.00031 20.5 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EJP61035.1 - 0.002 18.5 3.3 0.0068 16.8 0.1 3.4 3 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 EJP61035.1 - 0.0022 17.2 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EJP61035.1 - 0.0069 16.4 0.0 0.023 14.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJP61035.1 - 0.0082 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TLE_N PF03920.15 EJP61035.1 - 0.01 15.9 0.3 0.044 13.9 0.1 2.1 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Mg_chelatase PF01078.21 EJP61035.1 - 0.011 15.2 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EJP61035.1 - 0.011 15.5 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EJP61035.1 - 0.011 15.9 0.0 0.15 12.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 EJP61035.1 - 0.035 14.6 0.0 0.4 11.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EJP61035.1 - 0.048 12.8 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 EJP61035.1 - 0.1 12.6 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EJP61035.1 - 0.14 11.9 0.0 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EJP61035.1 - 0.14 12.0 0.1 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain HNH_4 PF13395.6 EJP61035.1 - 0.17 11.8 0.0 0.96 9.4 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease COG2 PF06148.11 EJP61035.1 - 0.99 9.5 3.0 1.6 8.8 0.5 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_28 PF13521.6 EJP61035.1 - 3.8 7.7 6.1 1.7 8.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain Ribosomal_S17 PF00366.20 EJP61036.1 - 1e-22 80.0 1.0 1e-22 80.0 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 EMG1 PF03587.14 EJP61037.1 - 4.8e-79 264.5 0.1 5.6e-79 264.3 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Cys_Met_Meta_PP PF01053.20 EJP61038.1 - 1.7e-28 99.2 0.0 2.5e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SPX PF03105.19 EJP61039.1 - 8.5e-63 213.6 7.8 3.8e-62 211.4 7.8 1.8 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.25 EJP61039.1 - 2.1e-08 33.9 10.5 2.1e-08 33.9 10.5 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP61039.1 - 6.1e-08 32.4 9.0 1.3e-07 31.4 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJP61039.1 - 1.4e-07 31.2 10.2 1.4e-07 31.2 10.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EJP61039.1 - 9.8e-07 28.8 9.7 9.8e-07 28.8 9.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EJP61039.1 - 1.7e-06 28.3 11.9 4.2e-06 27.0 11.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EJP61039.1 - 6.8e-06 26.0 8.8 1.8e-05 24.7 8.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EJP61039.1 - 7.8e-05 22.6 11.1 8.7e-05 22.4 9.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EJP61039.1 - 0.0077 16.1 8.2 0.018 14.9 8.2 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EJP61039.1 - 0.016 15.4 4.6 0.037 14.2 4.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EJP61039.1 - 0.018 14.8 4.8 0.018 14.8 4.8 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 EJP61039.1 - 0.075 13.1 0.9 0.15 12.1 0.9 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.7 EJP61039.1 - 0.11 12.8 9.5 0.36 11.2 9.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EJP61039.1 - 0.14 12.2 3.2 0.27 11.3 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ASFV_p27 PF06556.11 EJP61039.1 - 0.19 11.8 0.3 0.53 10.4 0.3 1.9 1 1 0 1 1 1 0 IAP-like protein p27 C-terminus Zn-ribbon_8 PF09723.10 EJP61039.1 - 4.2 7.6 5.8 2.3 8.4 1.7 2.4 1 1 1 2 2 2 0 Zinc ribbon domain Pkinase PF00069.25 EJP61042.1 - 0.0011 18.3 0.0 0.0046 16.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Radial_spoke_3 PF06098.11 EJP61042.1 - 0.004 16.5 13.4 0.0064 15.8 13.4 1.3 1 0 0 1 1 1 1 Radial spoke protein 3 Mpp10 PF04006.12 EJP61042.1 - 0.011 14.3 12.3 0.019 13.4 12.3 1.3 1 0 0 1 1 1 0 Mpp10 protein APH PF01636.23 EJP61042.1 - 0.015 15.3 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family UCR_TM PF02921.14 EJP61042.1 - 0.21 12.1 0.1 0.21 12.1 0.1 2.8 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region PIEZO PF15917.5 EJP61042.1 - 0.24 10.9 5.5 0.44 10.0 5.5 1.5 1 0 0 1 1 1 0 Piezo BCS1_N PF08740.11 EJP61044.1 - 7.2e-23 81.5 0.2 1.1e-22 80.9 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EJP61044.1 - 1.5e-19 70.7 0.0 2.6e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJP61044.1 - 0.002 18.6 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EJP61044.1 - 0.027 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MafB PF06255.13 EJP61044.1 - 0.058 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Neisseria toxin MafB AAA_5 PF07728.14 EJP61044.1 - 0.07 13.1 0.1 0.55 10.2 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EJP61044.1 - 0.077 13.3 0.1 0.7 10.2 0.0 2.5 2 2 1 3 3 3 0 AAA domain DUF815 PF05673.13 EJP61044.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 EJP61044.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain APH PF01636.23 EJP61046.1 - 3.7e-08 33.6 0.4 1.2e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP61046.1 - 0.0091 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RNase_H PF00075.24 EJP61047.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EJP61047.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DUF4423 PF14394.6 EJP61050.1 - 0.0077 16.0 0.3 0.0093 15.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) Exonuc_X-T_C PF08411.10 EJP61050.1 - 0.016 14.3 0.2 0.02 14.0 0.2 1.1 1 0 0 1 1 1 0 Exonuclease C-terminal DUF3050 PF11251.8 EJP61050.1 - 0.056 13.1 0.1 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3050) PdaC PF13739.6 EJP61050.1 - 0.2 12.6 1.7 7.4 7.6 0.0 2.1 1 1 1 2 2 2 0 Deacetylase PdaC Methyltransf_33 PF10017.9 EJP61052.1 - 1.1e-78 264.5 0.0 1.4e-78 264.2 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF3435 PF11917.8 EJP61053.1 - 5.5e-73 246.3 0.1 6.6e-73 246.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_int_SAM_4 PF13495.6 EJP61053.1 - 0.026 15.0 4.9 0.035 14.6 0.1 3.1 3 1 1 4 4 4 0 Phage integrase, N-terminal SAM-like domain AIM24 PF01987.17 EJP61054.1 - 1.4e-40 139.2 0.3 1.8e-40 138.9 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 SUIM_assoc PF16619.5 EJP61054.1 - 0.4 10.8 13.2 0.74 9.9 13.2 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 EJP61054.1 - 2.4 7.7 9.7 3.1 7.3 9.7 1.2 1 0 0 1 1 1 0 Spt20 family Aldo_ket_red PF00248.21 EJP61055.1 - 1.3e-41 142.7 0.0 6.5e-32 110.9 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family DUF2992 PF11208.8 EJP61057.1 - 0.33 11.2 8.1 1.9 8.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Lipoprotein_6 PF01441.19 EJP61057.1 - 7.3 6.6 8.4 2.1 8.3 1.4 2.1 1 1 1 2 2 2 0 Lipoprotein Epimerase PF01370.21 EJP61058.1 - 4e-10 39.6 0.0 5.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP61058.1 - 7.8e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EJP61058.1 - 0.00042 19.9 0.0 0.00083 19.0 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EJP61058.1 - 0.022 13.9 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.20 EJP61058.1 - 0.088 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1100 PF06500.11 EJP61059.1 - 1.6e-12 47.0 0.0 2.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 EJP61059.1 - 2.3e-10 41.5 8.0 9.2e-10 39.5 6.1 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP61059.1 - 4.5e-09 35.9 0.2 4.5e-08 32.7 0.2 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EJP61059.1 - 6.6e-07 29.0 1.2 1.8e-06 27.6 0.2 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EJP61059.1 - 5.1e-06 26.3 0.1 2e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 EJP61059.1 - 0.00071 19.2 0.1 0.68 9.4 0.0 3.1 3 0 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EJP61059.1 - 0.0013 18.6 0.4 0.025 14.4 0.1 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EJP61059.1 - 0.043 13.6 0.0 0.8 9.5 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 EJP61059.1 - 0.062 12.0 0.4 0.14 10.8 0.2 1.9 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF4398 PF14346.6 EJP61059.1 - 9.2 7.0 6.9 2.3 8.9 2.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) Fungal_trans PF04082.18 EJP61061.1 - 1.9e-21 76.3 0.1 3.6e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP61061.1 - 4.2e-07 30.0 11.1 7.8e-07 29.1 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CC PF04942.14 EJP61062.1 - 0.54 10.5 0.1 0.54 10.5 0.1 4.3 5 0 0 5 5 5 0 CC domain FAD_binding_4 PF01565.23 EJP61063.1 - 6.3e-21 74.6 0.5 1.4e-20 73.4 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP61063.1 - 2.5e-08 33.9 0.0 5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EJP61063.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RNase_H PF00075.24 EJP61064.1 - 3.9e-24 85.5 0.0 6.6e-24 84.7 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EJP61064.1 - 7.3e-05 22.6 0.0 0.004 16.9 0.0 2.5 1 1 0 1 1 1 1 Reverse transcriptase-like TetR_C_12 PF16914.5 EJP61064.1 - 0.035 14.2 1.5 0.063 13.4 1.5 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal FAD_binding_4 PF01565.23 EJP61065.1 - 2e-17 63.2 0.2 4.9e-17 62.0 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP61065.1 - 6.3e-08 32.6 0.1 1.1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like TMEM206 PF15122.6 EJP61066.1 - 0.026 13.7 1.3 0.046 12.9 0.2 1.8 2 0 0 2 2 2 0 TMEM206 protein family RicinB_lectin_2 PF14200.6 EJP61067.1 - 2.6e-11 44.1 1.5 3.5e-08 34.1 0.1 2.7 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EJP61067.1 - 2.6e-06 27.7 0.1 1.3e-05 25.4 0.1 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Creatinase_N_2 PF16189.5 EJP61068.1 - 6.2e-52 175.9 0.6 5.2e-51 172.9 0.6 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EJP61068.1 - 1.4e-47 162.1 0.0 2.2e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EJP61068.1 - 6.6e-22 78.6 0.2 1.7e-17 64.3 0.0 2.7 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EJP61068.1 - 1.1e-16 60.6 0.0 5.6e-16 58.4 0.0 2.4 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 tRNA-synt_1b PF00579.25 EJP61069.1 - 3.8e-54 184.0 0.0 7.5e-34 117.4 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) Importin_rep_3 PF18806.1 EJP61070.1 - 0.016 15.2 0.0 0.076 13.1 0.0 2.1 2 0 0 2 2 2 0 Importin 13 repeat HEAT PF02985.22 EJP61070.1 - 0.15 12.4 3.2 0.75 10.2 0.5 3.2 2 0 0 2 2 2 0 HEAT repeat Ribosomal_S10 PF00338.22 EJP61071.1 - 3.6e-24 84.8 0.0 5e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_2c PF01411.19 EJP61071.1 - 0.19 10.2 0.1 0.25 9.8 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Fcf2 PF08698.11 EJP61072.1 - 8.8e-32 109.4 0.8 2.8e-31 107.7 0.2 1.9 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.23 EJP61073.1 - 2.8e-19 69.1 0.5 5.1e-19 68.3 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EJP61073.1 - 9.3e-16 58.4 0.3 1.9e-15 57.4 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pol_alpha_B_N PF08418.10 EJP61073.1 - 0.039 13.9 0.1 0.048 13.6 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CENP-X PF09415.10 EJP61073.1 - 0.048 14.0 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.12 EJP61074.1 - 3.5e-112 374.9 7.0 8.7e-112 373.6 7.0 1.7 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like MutL_C PF08676.11 EJP61074.1 - 0.019 14.7 3.0 0.11 12.3 0.0 3.1 3 0 0 3 3 3 0 MutL C terminal dimerisation domain DUF4201 PF13870.6 EJP61074.1 - 0.096 12.4 11.0 0.047 13.4 6.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.12 EJP61074.1 - 0.1 12.6 13.6 0.67 10.0 4.1 3.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3510 PF12022.8 EJP61074.1 - 0.13 12.7 7.8 4 7.8 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3510) zf-RING_9 PF13901.6 EJP61074.1 - 1.4 8.9 6.0 0.76 9.7 3.0 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Sec8_exocyst PF04048.14 EJP61074.1 - 3.5 7.5 12.2 0.92 9.4 4.2 3.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain RRM_2 PF04059.12 EJP61075.1 - 5.8e-21 74.5 0.4 1e-20 73.8 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 Sad1_UNC PF07738.13 EJP61076.1 - 1.2e-32 112.7 0.0 2.2e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal TPR_19 PF14559.6 EJP61076.1 - 2.7e-10 40.6 20.2 0.0027 18.2 0.5 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJP61076.1 - 5e-10 39.9 27.6 0.00021 21.9 0.5 5.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EJP61076.1 - 2.3e-09 36.8 5.0 0.52 10.0 0.2 5.9 4 2 2 6 6 6 4 TPR repeat TPR_2 PF07719.17 EJP61076.1 - 1.9e-07 30.7 20.4 0.025 14.7 0.0 8.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP61076.1 - 2.6e-06 27.8 20.3 0.03 15.1 0.1 7.9 5 1 3 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EJP61076.1 - 0.00031 20.4 16.2 0.23 11.4 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJP61076.1 - 0.00045 20.4 1.8 15 6.2 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 EJP61076.1 - 0.00091 19.5 12.1 0.85 10.0 0.2 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP61076.1 - 0.00099 19.0 9.4 0.36 11.0 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP61076.1 - 0.0012 19.1 4.0 4.5 7.6 0.0 3.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EJP61076.1 - 0.0018 18.5 18.1 0.15 12.4 0.0 5.4 4 1 2 6 6 6 3 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EJP61076.1 - 0.0022 18.5 2.6 1.2 9.6 0.0 3.7 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_8 PF13181.6 EJP61076.1 - 0.0035 17.4 10.2 0.41 11.0 0.0 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJP61076.1 - 0.015 15.5 10.0 0.26 11.5 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 EJP61076.1 - 0.024 13.6 0.6 0.093 11.6 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 SAM_2 PF07647.17 EJP61077.1 - 4.1e-09 36.4 0.1 7.1e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EJP61077.1 - 0.00011 22.6 0.2 0.00021 21.7 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 EJP61077.1 - 0.046 13.8 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif DUF4508 PF14969.6 EJP61077.1 - 0.12 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Ribosomal_L29e PF01779.17 EJP61078.1 - 2.5e-22 78.9 8.8 3.9e-22 78.3 8.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Mito_carr PF00153.27 EJP61079.1 - 2.5e-52 174.7 1.9 2.7e-18 65.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 EJP61080.1 - 4.8e-31 107.9 0.0 7e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EJP61080.1 - 3.1e-10 40.5 0.1 5e-07 30.1 0.0 3.3 2 1 0 2 2 2 1 Calpain large subunit, domain III zf-C2H2 PF00096.26 EJP61081.1 - 6.4e-07 29.5 13.8 0.0049 17.3 2.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP61081.1 - 0.044 14.2 13.9 4.6 7.8 0.3 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP61081.1 - 0.85 10.6 15.2 0.1 13.5 1.7 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 EJP61081.1 - 1.7 9.0 7.1 0.68 10.3 1.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ADH_N PF08240.12 EJP61083.1 - 2e-29 101.6 2.8 3.3e-29 101.0 2.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP61083.1 - 3.6e-14 52.9 0.0 5.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EJP61083.1 - 9.9e-05 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 EJP61083.1 - 0.00049 20.0 0.1 0.0014 18.5 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 EJP61083.1 - 0.002 17.5 0.1 0.0037 16.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EJP61083.1 - 0.003 18.6 0.0 0.0054 17.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sen15 PF09631.10 EJP61084.1 - 5e-27 94.1 0.1 8.5e-27 93.4 0.1 1.4 1 1 0 1 1 1 1 Sen15 protein DUF5126 PF17166.4 EJP61084.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) HET PF06985.11 EJP61086.1 - 1.7e-16 60.9 0.3 4.9e-16 59.4 0.2 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CC PF04942.14 EJP61086.1 - 0.11 12.7 0.9 0.45 10.8 0.1 2.4 2 0 0 2 2 2 0 CC domain zf-C2H2 PF00096.26 EJP61087.1 - 0.0015 18.9 21.9 0.041 14.3 1.0 5.1 4 2 0 4 4 4 3 Zinc finger, C2H2 type zf-C2HE PF16278.5 EJP61087.1 - 0.27 11.7 2.0 2.8 8.5 0.0 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3295 PF11702.8 EJP61088.1 - 6.4e-46 157.8 8.4 1.1e-40 140.5 2.1 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3295) FAD_binding_8 PF08022.12 EJP61089.1 - 7.5e-05 22.8 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EJP61089.1 - 0.0067 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EJP61089.1 - 0.048 13.8 2.0 0.054 13.6 0.6 1.8 2 0 0 2 2 2 0 Ferric reductase like transmembrane component Nucleo_P87 PF07267.11 EJP61089.1 - 0.088 11.7 1.1 0.12 11.2 1.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 UPF0060 PF02694.15 EJP61091.1 - 0.01 16.1 2.1 0.021 15.0 2.1 1.5 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family DUF4404 PF14357.6 EJP61092.1 - 0.11 13.2 0.0 1.9 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Pkinase PF00069.25 EJP61093.1 - 8.1e-12 45.0 0.0 1.5e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61093.1 - 4.7e-06 26.1 0.0 2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EJP61093.1 - 0.00025 20.5 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP61093.1 - 0.00034 20.6 0.1 0.0023 17.9 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP61093.1 - 0.0027 17.3 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 EJP61093.1 - 0.0052 16.1 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EJP61093.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EJP61096.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EJP61096.1 - 6.4e-05 23.0 0.0 6.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EJP61096.1 - 0.0011 18.3 0.0 0.0032 16.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EJP61096.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EJP61096.1 - 0.036 12.8 0.1 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase SRP-alpha_N PF04086.13 EJP61096.1 - 0.65 9.9 7.6 4.3 7.2 4.5 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Menin PF05053.13 EJP61096.1 - 1.4 7.2 3.8 2.1 6.6 3.8 1.1 1 0 0 1 1 1 0 Menin DUF2828 PF11443.8 EJP61096.1 - 5 5.1 5.8 3.2 5.7 4.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) ACCA PF03255.14 EJP61096.1 - 9.3 6.1 9.2 2.9 7.8 5.7 1.8 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4611 PF15387.6 EJP61097.1 - 0.01 16.0 3.1 0.095 12.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TnpV PF14198.6 EJP61097.1 - 0.035 14.1 0.3 0.091 12.7 0.0 1.8 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Zein-binding PF04576.15 EJP61097.1 - 0.3 11.4 4.1 0.17 12.2 1.4 1.9 2 0 0 2 2 2 0 Zein-binding BCS1_N PF08740.11 EJP61099.1 - 8.1e-21 74.9 0.1 1.5e-20 73.9 0.0 1.5 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EJP61099.1 - 2.5e-19 70.0 0.0 4.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EJP61099.1 - 0.011 15.4 0.0 0.038 13.7 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EJP61099.1 - 0.043 14.2 0.1 0.3 11.4 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EJP61099.1 - 0.058 13.7 0.3 0.99 9.7 0.1 2.9 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 EJP61099.1 - 0.062 13.3 0.1 0.32 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EJP61099.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MafB PF06255.13 EJP61099.1 - 0.095 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Neisseria toxin MafB TIP49 PF06068.13 EJP61099.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain GTP_EFTU PF00009.27 EJP61101.1 - 2e-10 40.6 0.0 4.2e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EJP61101.1 - 0.094 12.5 1.0 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein URO-D PF01208.17 EJP61102.1 - 1.2e-119 399.5 0.0 5.3e-113 377.7 0.0 2.0 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) DUF3602 PF12223.8 EJP61103.1 - 1.9e-16 60.4 12.5 2.6e-11 44.0 1.2 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) BNIP3 PF06553.12 EJP61103.1 - 0.12 12.0 1.6 0.2 11.3 1.1 1.4 1 1 0 1 1 1 0 BNIP3 WD40 PF00400.32 EJP61104.1 - 8.5e-11 42.2 3.9 0.38 11.7 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP61104.1 - 0.045 14.1 0.0 5.6 7.3 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-H2C2_2 PF13465.6 EJP61105.1 - 5.9e-11 42.3 13.8 0.00045 20.5 0.9 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EJP61105.1 - 8.3e-10 38.6 22.7 0.0027 18.1 8.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP61105.1 - 4.7e-06 27.0 18.5 0.033 15.0 6.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP61105.1 - 0.028 14.7 8.4 0.66 10.3 2.7 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EJP61105.1 - 0.039 14.0 16.2 5.4 7.1 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 EJP61105.1 - 0.076 12.9 5.7 3.6 7.6 0.3 2.7 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Rad50_zn_hook PF04423.14 EJP61105.1 - 0.1 12.5 0.3 0.24 11.3 0.3 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-Di19 PF05605.12 EJP61105.1 - 0.1 12.9 8.7 0.065 13.5 6.2 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 EJP61105.1 - 0.22 11.4 2.8 1.6 8.6 0.3 2.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 EJP61105.1 - 0.35 10.9 9.3 1.4 9.0 4.7 3.3 2 1 1 3 3 3 0 BED zinc finger Sporozoite_P67 PF05642.11 EJP61105.1 - 0.51 8.4 6.1 0.92 7.5 6.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-met PF12874.7 EJP61105.1 - 0.58 10.6 7.8 25 5.5 2.7 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DZR PF12773.7 EJP61105.1 - 0.59 10.2 5.4 7.7 6.6 5.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-C2HE PF16278.5 EJP61105.1 - 0.65 10.5 15.1 0.66 10.5 0.8 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 EJP61105.1 - 1.7 9.0 11.3 1.5 9.2 1.8 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 EJP61105.1 - 2.9 8.1 6.4 6 7.1 1.2 2.6 1 1 2 3 3 3 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 EJP61105.1 - 5.2 6.8 10.0 0.63 9.7 0.2 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain 2-oxoacid_dh PF00198.23 EJP61106.1 - 9.1e-79 264.2 0.1 1.4e-78 263.6 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EJP61106.1 - 2.8e-15 55.9 1.1 5.9e-15 54.9 1.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Hamartin PF04388.12 EJP61106.1 - 0.015 14.0 2.3 0.017 13.8 2.3 1.2 1 0 0 1 1 1 0 Hamartin protein DUF3614 PF12267.8 EJP61106.1 - 0.037 14.5 4.4 0.079 13.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.6 EJP61106.1 - 0.077 12.8 0.3 0.66 9.8 0.1 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like Ndc1_Nup PF09531.10 EJP61106.1 - 0.25 10.0 7.2 0.34 9.5 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EJP61106.1 - 0.47 9.1 5.4 0.67 8.7 5.4 1.1 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 EJP61106.1 - 1.9 9.0 8.1 3.2 8.3 8.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Apt1 PF10351.9 EJP61106.1 - 2.2 7.0 8.3 3.1 6.6 8.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Histone_H2A_C PF16211.5 EJP61107.1 - 9.3e-21 73.3 2.2 1.7e-20 72.5 2.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EJP61107.1 - 7.1e-17 62.0 0.0 9.6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EJP61107.1 - 1.1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EJP61108.1 - 5.4e-22 78.6 2.1 6.3e-22 78.3 2.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EJP61108.1 - 2.4e-05 24.5 0.1 0.0001 22.5 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EJP61108.1 - 0.00024 21.5 0.0 0.00043 20.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 EJP61108.1 - 0.037 13.7 0.1 0.091 12.4 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 EJP61109.1 - 1.9e-13 50.2 0.0 4.6e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EJP61109.1 - 7e-09 35.4 0.9 1.8e-08 34.1 0.9 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EJP61109.1 - 2.8e-05 24.1 0.1 6.8e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 G-patch domain Peptidase_C54 PF03416.19 EJP61110.1 - 1.1e-60 205.4 0.1 1e-41 143.2 0.0 3.4 2 1 2 4 4 4 3 Peptidase family C54 DnaJ PF00226.31 EJP61111.1 - 5.9e-22 77.6 0.4 5.9e-22 77.6 0.4 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 EJP61111.1 - 8.5e-11 41.9 2.3 1.8e-10 40.8 2.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJP61111.1 - 1.1e-08 35.1 1.8 2.4e-08 34.1 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EJP61111.1 - 0.00027 21.2 0.6 0.00056 20.2 0.6 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EJP61111.1 - 0.0052 17.2 0.5 0.011 16.1 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP61111.1 - 0.0087 16.8 0.2 0.021 15.6 0.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EJP61111.1 - 0.32 11.0 2.2 0.63 10.1 2.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP61112.1 - 0.022 15.2 0.0 0.022 15.2 0.0 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type RVT_1 PF00078.27 EJP61112.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EJP61112.1 - 0.14 12.3 2.3 0.36 11.0 2.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_4 PF13894.6 EJP61112.1 - 0.18 12.7 0.1 0.18 12.7 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Exo_endo_phos_2 PF14529.6 EJP61115.1 - 1.5e-18 66.7 0.5 4.2e-18 65.3 0.1 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EJP61115.1 - 8.6e-09 35.2 0.2 2.3e-08 33.9 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C2H2 PF00096.26 EJP61115.1 - 8.3e-05 22.8 0.2 0.0003 21.1 0.2 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP61115.1 - 0.0006 20.4 0.3 0.0006 20.4 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EJP61115.1 - 0.001 19.0 0.5 0.0021 18.0 0.5 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EJP61115.1 - 0.0076 16.6 0.5 0.018 15.4 0.5 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EJP61115.1 - 0.13 12.6 0.2 0.36 11.2 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3435 PF11917.8 EJP61116.1 - 3.8e-15 55.7 0.1 8.7e-15 54.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) zf-H2C2_2 PF13465.6 EJP61116.1 - 4.5e-05 23.7 10.6 0.12 12.9 0.1 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.12 EJP61116.1 - 0.0087 16.3 15.9 0.029 14.7 4.0 2.9 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 EJP61116.1 - 0.11 12.5 1.4 6.6 6.9 0.1 2.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 EJP61116.1 - 1.8 8.4 8.0 0.28 11.0 0.7 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type PAD PF03068.15 EJP61118.1 - 4.9e-122 407.7 0.0 6.3e-122 407.3 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) zf-met PF12874.7 EJP61119.1 - 1.7e-13 50.5 21.0 0.00021 21.6 2.4 6.3 6 1 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EJP61119.1 - 1.8e-08 34.6 21.3 0.016 15.5 1.0 6.1 2 2 4 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EJP61119.1 - 2.1e-08 34.3 26.6 0.2 12.6 0.1 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP61119.1 - 7.9e-08 32.4 34.1 0.00011 22.4 0.3 6.1 6 1 0 6 6 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EJP61119.1 - 1.6e-05 24.8 15.0 0.11 12.5 0.1 5.3 4 1 1 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP61119.1 - 0.0065 16.9 33.0 0.042 14.3 0.1 6.9 7 0 0 7 7 7 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP61119.1 - 0.051 14.0 31.4 0.9 10.1 0.2 6.8 6 0 0 6 6 6 0 Zinc-finger double domain zf_ZIC PF18366.1 EJP61119.1 - 0.22 11.7 9.0 14 5.9 0.1 4.7 4 1 2 6 6 5 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 EJP61119.1 - 0.48 10.2 12.5 0.57 10.0 0.1 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type RIG-I_C-RD PF11648.8 EJP61119.1 - 0.83 9.9 6.0 1.5 9.0 4.5 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I zf-C2HE PF16278.5 EJP61119.1 - 1 9.9 12.8 29 5.2 3.9 4.5 4 1 1 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 EJP61119.1 - 2.5 7.7 18.5 1.4 8.6 0.2 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger PNP_UDP_1 PF01048.20 EJP61120.1 - 8.2e-14 51.4 0.4 2.4e-13 49.9 0.4 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily RVT_1 PF00078.27 EJP61122.1 - 1.1e-29 103.5 0.0 1.7e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) POC3_POC4 PF10448.9 EJP61125.1 - 0.13 12.3 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 F-box-like PF12937.7 EJP61127.1 - 3.5e-10 39.6 0.0 3.5e-10 39.6 0.0 3.4 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 EJP61127.1 - 3.1e-07 30.6 6.0 0.021 15.2 0.1 5.3 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EJP61127.1 - 0.02 14.6 0.5 9.3 6.1 0.1 4.4 4 1 2 6 6 6 0 Leucine rich repeat ANAPC4 PF12896.7 EJP61129.1 - 0.047 13.2 0.1 0.048 13.2 0.1 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 TRCF PF03461.15 EJP61129.1 - 0.097 13.1 0.2 0.12 12.7 0.2 1.4 1 1 0 1 1 1 0 TRCF domain HNH_2 PF13391.6 EJP61133.1 - 9.1e-12 44.9 0.1 3.2e-11 43.2 0.1 2.0 1 0 0 1 1 1 1 HNH endonuclease ORC6 PF05460.13 EJP61133.1 - 0.39 9.9 4.2 1 8.6 0.9 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) HNH_2 PF13391.6 EJP61134.1 - 1e-08 35.1 0.4 2.2e-08 34.1 0.4 1.5 1 1 0 1 1 1 1 HNH endonuclease Ank_2 PF12796.7 EJP61135.1 - 1.1e-18 67.5 1.1 4.9e-09 36.6 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP61135.1 - 9e-13 48.5 0.2 0.042 14.4 0.0 4.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP61135.1 - 3.3e-11 43.2 2.4 0.058 13.7 0.0 5.3 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP61135.1 - 1.7e-09 37.1 2.0 0.062 13.9 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EJP61135.1 - 2.5e-05 24.5 0.2 0.4 11.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat BTB PF00651.31 EJP61135.1 - 0.01 16.0 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain Acetyltransf_3 PF13302.7 EJP61135.1 - 0.049 14.3 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GLEYA PF10528.9 EJP61136.1 - 7.6e-27 93.6 1.3 7.6e-27 93.6 1.3 3.2 2 1 1 3 3 3 1 GLEYA domain PA14 PF07691.12 EJP61136.1 - 3.9e-05 23.5 0.4 0.00012 21.9 0.4 1.9 1 0 0 1 1 1 1 PA14 domain NACHT PF05729.12 EJP61137.1 - 1.7e-11 44.3 0.1 1.1e-10 41.7 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EJP61137.1 - 3.1e-08 34.2 0.1 8.2e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.13 EJP61137.1 - 0.00035 20.4 0.1 0.0011 18.8 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 EJP61137.1 - 0.00076 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EJP61137.1 - 0.0026 18.4 0.1 0.0073 16.9 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA PF00004.29 EJP61137.1 - 0.005 17.3 0.1 0.019 15.4 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EJP61137.1 - 0.0087 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EJP61137.1 - 0.011 16.0 0.0 0.041 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EJP61137.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EJP61137.1 - 0.029 13.8 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF746 PF05344.11 EJP61137.1 - 0.035 13.9 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 1 0 Domain of Unknown Function (DUF746) Hydrolase_4 PF12146.8 EJP61137.1 - 0.055 12.7 0.0 0.18 11.0 0.0 1.8 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AAA_30 PF13604.6 EJP61137.1 - 0.061 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EJP61137.1 - 0.072 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.23 EJP61137.1 - 0.073 13.1 0.1 0.73 9.9 0.2 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cutinase PF01083.22 EJP61137.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase AAA_33 PF13671.6 EJP61137.1 - 0.16 12.1 0.3 1.9 8.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain LIDHydrolase PF10230.9 EJP61137.1 - 0.17 11.4 0.1 5.2 6.5 0.0 2.6 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase SET PF00856.28 EJP61138.1 - 1.1e-10 42.2 0.2 6.6e-10 39.6 0.2 2.3 1 1 0 1 1 1 1 SET domain Dynamin_M PF01031.20 EJP61139.1 - 3.9e-05 23.0 0.0 6.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Ank_2 PF12796.7 EJP61140.1 - 4.3e-51 171.4 12.2 1.7e-16 60.6 0.3 4.9 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP61140.1 - 1.2e-37 127.8 9.5 5.3e-09 36.4 0.2 7.2 3 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EJP61140.1 - 1.1e-34 117.4 21.0 3.8e-08 33.4 0.3 9.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EJP61140.1 - 3.6e-30 103.6 2.9 2.5e-07 30.8 0.1 7.3 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP61140.1 - 6.2e-22 75.3 8.1 0.0002 21.5 0.1 9.4 9 0 0 9 9 9 4 Ankyrin repeat NACHT PF05729.12 EJP61140.1 - 5.3e-12 46.0 0.1 1.1e-11 45.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EJP61140.1 - 5.1e-06 27.0 0.1 2.4e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EJP61140.1 - 0.00022 21.5 0.0 0.0013 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EJP61140.1 - 0.0022 17.2 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 EJP61140.1 - 0.0059 17.0 0.0 0.026 15.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PNP_UDP_1 PF01048.20 EJP61140.1 - 0.025 13.8 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 0 Phosphorylase superfamily AAA_14 PF13173.6 EJP61140.1 - 0.056 13.5 0.0 0.98 9.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJP61140.1 - 0.066 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ZZ PF00569.17 EJP61140.1 - 0.12 12.2 6.8 0.28 11.0 6.8 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type Dimer_Tnp_hAT PF05699.14 EJP61141.1 - 8.2e-16 57.6 1.0 2e-15 56.3 1.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 EJP61142.1 - 5.5e-35 120.9 0.0 1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EJP61142.1 - 3.2e-21 75.4 0.0 1.5e-20 73.2 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 EJP61142.1 - 3.8e-05 23.6 2.4 7.2e-05 22.7 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle SlyX PF04102.12 EJP61142.1 - 0.00016 22.2 0.9 0.0005 20.6 0.9 1.9 1 0 0 1 1 1 1 SlyX Exo_endo_phos PF03372.23 EJP61142.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spc7 PF08317.11 EJP61142.1 - 0.094 11.6 1.8 0.22 10.4 1.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EJP61142.1 - 0.77 9.8 4.3 1.3 9.1 3.4 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.25 EJP61143.1 - 6.6e-34 117.5 0.0 3.6e-26 92.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61143.1 - 9.7e-25 87.3 0.0 1.2e-20 73.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.20 EJP61143.1 - 0.00063 19.4 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EJP61143.1 - 0.028 13.8 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP61143.1 - 0.14 12.0 3.1 0.39 10.6 0.1 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family NAD_binding_6 PF08030.12 EJP61146.1 - 8.3e-10 39.0 0.0 1.6e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EJP61146.1 - 4.4e-08 33.2 0.0 8.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF4571 PF15137.6 EJP61146.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) DUF4405 PF14358.6 EJP61146.1 - 0.22 12.1 6.1 1.1 9.9 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Ferric_reduct PF01794.19 EJP61146.1 - 0.41 10.8 12.7 0.27 11.4 8.2 2.4 2 1 0 2 2 2 0 Ferric reductase like transmembrane component SH3_17 PF18350.1 EJP61147.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain JIP_LZII PF16471.5 EJP61148.1 - 0.04 14.1 2.0 0.04 14.1 2.0 3.6 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF3086 PF11285.8 EJP61148.1 - 0.093 11.8 8.3 0.46 9.6 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DUF1192 PF06698.11 EJP61148.1 - 0.61 10.2 14.1 3 8.0 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF1664 PF07889.12 EJP61148.1 - 0.67 10.0 7.7 0.092 12.8 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 EJP61148.1 - 1 7.9 17.7 0.49 8.9 2.8 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A bZIP_1 PF00170.21 EJP61148.1 - 1 9.5 9.5 1.3 9.2 0.3 3.3 3 0 0 3 3 3 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 EJP61148.1 - 2.8 8.2 20.3 0.91 9.8 5.8 2.7 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Vps51 PF08700.11 EJP61148.1 - 3.2 7.9 8.8 4 7.6 0.4 3.4 2 2 1 3 3 3 0 Vps51/Vps67 Filament PF00038.21 EJP61149.1 - 3.3e-05 23.7 6.5 5.1e-05 23.0 6.5 1.2 1 0 0 1 1 1 1 Intermediate filament protein NUDE_C PF04880.13 EJP61149.1 - 0.033 14.7 0.9 0.083 13.4 0.1 1.9 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region KELK PF15796.5 EJP61149.1 - 0.044 14.2 2.7 0.044 14.2 2.7 2.5 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 EJP61149.1 - 0.066 12.6 7.1 0.11 11.8 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM184 PF15665.5 EJP61149.1 - 0.075 12.8 11.1 4.1 7.1 11.0 2.2 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B TPR_MLP1_2 PF07926.12 EJP61149.1 - 0.11 12.6 14.0 0.075 13.1 5.1 3.3 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 EJP61149.1 - 0.15 10.2 6.3 0.22 9.7 6.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sipho_Gp157 PF05565.11 EJP61149.1 - 0.62 10.0 7.0 1.1 9.3 7.0 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 FapA PF03961.13 EJP61149.1 - 0.68 8.5 7.1 0.49 8.9 4.9 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A ZapB PF06005.12 EJP61149.1 - 0.75 10.3 14.3 1.5 9.3 9.7 2.7 1 1 1 2 2 2 0 Cell division protein ZapB NYD-SP28 PF14772.6 EJP61149.1 - 1 9.5 11.1 0.26 11.3 7.3 1.9 2 0 0 2 2 2 0 Sperm tail APG6_N PF17675.1 EJP61149.1 - 1.4 9.5 10.3 2.9 8.4 10.3 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Vir_act_alpha_C PF10400.9 EJP61149.1 - 1.6 9.5 5.5 1 10.1 0.3 2.9 1 1 2 3 3 3 0 Virulence activator alpha C-term DUF2968 PF11180.8 EJP61149.1 - 2.1 7.9 11.4 12 5.5 9.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) YabA PF06156.13 EJP61149.1 - 2.8 8.6 7.7 15 6.2 3.3 2.6 1 1 1 2 2 2 0 Initiation control protein YabA NACHT PF05729.12 EJP61150.1 - 2.5e-10 40.5 0.1 6.7e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EJP61150.1 - 4.2e-06 27.2 0.0 1.5e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 EJP61150.1 - 2.7e-05 24.9 0.8 5.1e-05 24.0 0.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNA_helicase PF00910.22 EJP61150.1 - 0.00087 19.7 0.0 0.026 14.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Hydrolase_4 PF12146.8 EJP61150.1 - 0.0012 18.2 0.0 0.003 16.9 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA_22 PF13401.6 EJP61150.1 - 0.0022 18.3 0.1 0.011 16.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EJP61150.1 - 0.0039 16.8 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.14 EJP61150.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) KAP_NTPase PF07693.14 EJP61150.1 - 0.014 14.6 0.7 0.072 12.3 0.0 2.3 2 1 1 3 3 3 0 KAP family P-loop domain AAA PF00004.29 EJP61150.1 - 0.059 13.8 0.1 0.23 11.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Lipase_3 PF01764.25 EJP61150.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF726 PF05277.12 EJP61150.1 - 0.089 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) AAA_33 PF13671.6 EJP61150.1 - 0.095 12.9 1.3 0.54 10.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain Abhydrolase_9 PF10081.9 EJP61150.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family ABC_tran PF00005.27 EJP61150.1 - 0.15 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Torsin PF06309.11 EJP61150.1 - 0.18 11.9 0.0 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Torsin DUF3435 PF11917.8 EJP61151.1 - 7.3e-06 25.2 0.8 1.2e-05 24.5 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) FOXP-CC PF16159.5 EJP61151.1 - 0.84 10.3 7.3 0.47 11.1 0.6 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF3435 PF11917.8 EJP61152.1 - 8.4e-10 38.1 2.2 1.1e-05 24.6 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3435) Phage_int_SAM_5 PF13102.6 EJP61152.1 - 0.00013 22.3 1.6 0.00023 21.4 1.6 1.4 1 0 0 1 1 1 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 EJP61152.1 - 0.019 15.4 2.7 0.071 13.6 2.7 2.0 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Init_tRNA_PT PF04179.12 EJP61152.1 - 0.053 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Retrotrans_gag PF03732.17 EJP61152.1 - 0.11 12.7 0.4 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Myb_DNA-binding PF00249.31 EJP61153.1 - 1.3 9.3 7.4 0.1 12.8 2.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP61153.1 - 8 6.8 7.2 1.4 9.2 2.8 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain SLX9 PF15341.6 EJP61153.1 - 8.9 6.7 10.9 1.3 9.4 2.3 2.8 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 Ank_2 PF12796.7 EJP61154.1 - 3.4e-40 136.5 0.0 8.3e-15 55.2 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP61154.1 - 3.1e-39 132.9 1.5 1.3e-12 47.9 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EJP61154.1 - 1.3e-30 104.5 1.9 1.3e-07 31.7 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 EJP61154.1 - 1.3e-30 102.0 0.0 1.6e-05 24.9 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EJP61154.1 - 1.8e-24 85.5 3.4 4.8e-08 33.1 0.2 5.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) DBD_Tnp_Hermes PF10683.9 EJP61154.1 - 0.068 12.9 0.2 1.7 8.4 0.0 2.7 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain Lipin_N PF04571.14 EJP61154.1 - 0.14 12.1 0.0 13 5.8 0.0 2.5 1 1 1 2 2 2 0 lipin, N-terminal conserved region HEAT_2 PF13646.6 EJP61155.1 - 1.2e-21 76.9 19.7 3.9e-11 43.2 3.2 3.4 2 1 0 3 3 2 2 HEAT repeats HEAT PF02985.22 EJP61155.1 - 3.4e-18 64.2 8.9 0.019 15.2 0.1 6.7 6 0 0 6 6 6 5 HEAT repeat NACHT PF05729.12 EJP61155.1 - 3.9e-16 59.4 0.0 1.2e-15 57.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain HEAT_EZ PF13513.6 EJP61155.1 - 5.1e-09 36.5 14.1 0.09 13.3 0.4 5.5 5 0 0 5 5 5 3 HEAT-like repeat NLRC4_HD2 PF17776.1 EJP61155.1 - 1.3e-07 32.2 0.3 9.1e-07 29.5 0.2 2.5 2 1 0 2 2 1 1 NLRC4 helical domain HD2 Cnd1 PF12717.7 EJP61155.1 - 5.3e-07 29.8 6.7 2.7 8.0 0.1 5.2 1 1 4 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 EJP61155.1 - 9.5e-07 29.0 19.8 0.0047 17.2 0.3 6.5 6 0 0 6 6 6 2 HEAT repeat associated with sister chromatid cohesion NB-ARC PF00931.22 EJP61155.1 - 0.0001 21.6 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PGAP1 PF07819.13 EJP61155.1 - 0.00032 20.5 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein RTP1_C1 PF10363.9 EJP61155.1 - 0.00096 19.3 0.1 16 5.8 0.0 4.2 2 1 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF676 PF05057.14 EJP61155.1 - 0.00098 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Adaptin_N PF01602.20 EJP61155.1 - 0.0034 16.0 1.8 0.26 9.8 0.2 2.2 2 0 0 2 2 2 2 Adaptin N terminal region AAA_16 PF13191.6 EJP61155.1 - 0.0072 16.7 0.1 0.048 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 EJP61155.1 - 0.0098 16.5 2.9 0.034 14.8 0.1 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.6 EJP61155.1 - 0.015 15.5 0.0 0.06 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EJP61155.1 - 0.028 14.3 0.1 0.067 13.1 0.1 1.6 1 0 0 1 1 1 0 NTPase Hydrolase_4 PF12146.8 EJP61155.1 - 0.03 13.6 0.0 0.08 12.2 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RasGEF_N_2 PF14663.6 EJP61155.1 - 0.035 14.5 1.5 8.4 6.9 0.0 4.4 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF726 PF05277.12 EJP61155.1 - 0.054 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Cutinase PF01083.22 EJP61155.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase AAA PF00004.29 EJP61155.1 - 0.099 13.1 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EJP61155.1 - 0.11 13.1 0.0 0.35 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Palm_thioest PF02089.15 EJP61155.1 - 0.18 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase TsaE PF02367.17 EJP61155.1 - 0.24 11.4 0.8 0.94 9.5 0.0 2.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EJP61155.1 - 0.25 11.0 0.6 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Glycos_transf_3 PF00591.21 EJP61156.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family, a/b domain F-box PF00646.33 EJP61157.1 - 0.0003 20.6 0.0 0.00071 19.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EJP61157.1 - 0.0078 16.1 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EJP61157.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box Bromo_TP_like PF17027.5 EJP61158.1 - 0.079 13.1 0.1 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Histone-fold protein Polysacc_synt_2 PF02719.15 EJP61160.1 - 0.038 13.1 0.1 0.06 12.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Rsd_AlgQ PF04353.13 EJP61161.1 - 0.0053 16.7 0.0 0.0079 16.2 0.0 1.3 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GrpE PF01025.19 EJP61161.1 - 0.091 12.4 4.0 0.12 12.0 4.0 1.2 1 0 0 1 1 1 0 GrpE Peptidase_S49_N PF08496.10 EJP61161.1 - 3.7 7.6 7.8 4.9 7.2 7.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PA_decarbox PF05870.11 EJP61162.1 - 2.2e-07 30.6 0.1 2.6e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Dynamin_N PF00350.23 EJP61163.1 - 4.6e-15 56.1 0.0 1.8e-14 54.2 0.0 2.1 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EJP61163.1 - 2.2e-05 24.5 0.0 0.06 13.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.27 EJP61163.1 - 0.00042 20.8 0.0 0.0016 18.9 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EJP61163.1 - 0.0042 17.5 1.7 0.01 16.2 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EJP61163.1 - 0.01 15.7 0.0 0.043 13.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 EJP61163.1 - 0.25 11.7 1.1 3 8.2 0.0 2.9 3 1 0 3 3 3 0 AAA domain APH PF01636.23 EJP61166.1 - 6.6e-15 55.7 0.1 1.8e-14 54.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EJP61166.1 - 0.00023 20.6 0.0 0.0012 18.3 0.0 2.2 2 1 0 2 2 2 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 EJP61166.1 - 0.083 12.1 0.0 0.23 10.7 0.0 1.5 1 1 0 1 1 1 0 Fructosamine kinase SF1-HH PF16275.5 EJP61168.1 - 6.3e-44 148.9 1.8 1.5e-43 147.8 1.8 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EJP61168.1 - 1.9e-11 43.5 11.3 1.3e-05 25.1 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EJP61168.1 - 1.7e-07 31.0 0.1 3.2e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EJP61168.1 - 9.6e-07 28.7 6.6 0.00047 20.0 3.6 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EJP61168.1 - 0.00017 21.4 7.6 0.04 13.8 0.4 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EJP61168.1 - 0.0014 18.3 5.0 0.55 10.0 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EJP61168.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 EJP61168.1 - 0.36 11.0 2.0 0.83 9.8 2.0 1.6 1 0 0 1 1 1 0 PHD-finger eIF3g PF12353.8 EJP61168.1 - 0.46 10.9 6.9 3.5 8.0 0.5 3.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Peptidase_M28 PF04389.17 EJP61169.1 - 2.4e-34 118.8 0.1 4.7e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EJP61169.1 - 0.0006 19.6 0.0 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DUF3687 PF12459.8 EJP61169.1 - 7.1 6.2 10.0 0.29 10.7 1.5 2.6 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein IGFBP PF00219.18 EJP61170.1 - 0.012 16.2 6.4 0.012 16.2 6.4 1.6 2 0 0 2 2 2 0 Insulin-like growth factor binding protein HhH-GPD PF00730.25 EJP61171.1 - 2e-19 70.0 0.0 3.8e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EJP61171.1 - 8e-08 31.8 0.7 2e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif Ribosomal_L11_N PF03946.14 EJP61172.1 - 1.5e-25 88.8 0.1 2.1e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EJP61172.1 - 3.5e-25 88.3 0.1 7.9e-25 87.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Methyltransf_24 PF13578.6 EJP61173.1 - 6.9e-17 62.4 0.0 1.1e-16 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EJP61173.1 - 8.8e-09 34.8 0.0 1.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.6 EJP61173.1 - 0.0022 18.7 0.0 0.0034 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 EJP61173.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase PCMT PF01135.19 EJP61173.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EJP61173.1 - 0.094 13.4 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EJP61173.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 EJP61174.1 - 3.3e-22 78.9 42.1 3.3e-22 78.9 42.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.8 EJP61175.1 - 2e-25 89.9 0.0 2.6e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RTP1_C2 PF10304.9 EJP61176.1 - 0.053 13.2 2.4 8.8 6.1 0.1 3.1 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 2 Zn-C2H2_12 PF18112.1 EJP61176.1 - 0.1 13.1 0.0 1.3e+02 3.1 0.0 3.1 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain CitT PF12431.8 EJP61176.1 - 1.5 9.2 9.1 44 4.6 0.3 3.4 3 0 0 3 3 3 0 Transcriptional regulator 2-oxogl_dehyd_N PF16078.5 EJP61176.1 - 2.4 7.8 9.8 28 4.4 0.3 3.2 3 0 0 3 3 3 0 2-oxoglutarate dehydrogenase N-terminus DUF3328 PF11807.8 EJP61177.1 - 3.3e-23 82.6 0.9 2.5e-22 79.7 0.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EJP61178.1 - 5.2e-43 147.4 1.0 6.3e-43 147.1 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) BCL9 PF11502.8 EJP61178.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Methyltransf_2 PF00891.18 EJP61179.1 - 7.8e-27 93.9 0.0 1.2e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DUF1926 PF09095.11 EJP61180.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) KH_8 PF17903.1 EJP61181.1 - 1.1e-30 105.5 0.0 2.5e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EJP61181.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 KH domain ADH_zinc_N PF00107.26 EJP61183.1 - 7.1e-14 51.9 0.6 1.7e-13 50.7 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP61183.1 - 3.6e-07 31.3 0.1 9.4e-07 29.9 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP61183.1 - 0.00021 21.1 0.0 0.00067 19.5 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sulf_transp PF04143.14 EJP61184.1 - 3.7e-28 99.0 32.1 3.7e-28 99.0 32.1 1.6 1 1 0 1 1 1 1 Sulphur transport Ribonuc_L-PSP PF01042.21 EJP61185.1 - 2.2e-23 82.6 0.0 2.5e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YqeY PF09424.10 EJP61186.1 - 1.8e-24 86.5 6.4 2.1e-24 86.2 6.4 1.1 1 0 0 1 1 1 1 Yqey-like protein ATP-grasp_2 PF08442.10 EJP61187.1 - 4e-77 258.3 1.3 4e-77 258.3 1.3 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EJP61187.1 - 4.8e-27 94.6 0.3 1.1e-26 93.5 0.3 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EJP61187.1 - 6.3e-08 32.4 0.2 1.4e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EJP61187.1 - 0.0046 16.7 3.2 0.019 14.8 0.8 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 EJP61187.1 - 0.035 14.4 0.1 0.22 11.8 0.0 2.2 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain RimK PF08443.11 EJP61187.1 - 0.045 13.3 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Na_H_Exchanger PF00999.21 EJP61188.1 - 1.5e-28 99.7 26.3 4.4e-28 98.1 20.2 2.5 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family TLD PF07534.16 EJP61189.1 - 1.2e-26 93.6 0.0 5e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 TLD HEM4 PF02602.15 EJP61190.1 - 5.8e-36 124.0 0.0 7.2e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.13 EJP61191.1 - 9.9e-30 103.0 1.5 1.4e-29 102.5 0.4 1.7 2 0 0 2 2 2 1 Erv1 / Alr family Glyco_trans_4_3 PF12000.8 EJP61191.1 - 0.032 13.9 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 group TPP_enzyme_N PF02776.18 EJP61192.1 - 1.4e-34 119.2 0.0 4.3e-34 117.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJP61192.1 - 1.8e-20 73.1 0.0 3.7e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EJP61192.1 - 1.5e-18 67.0 0.6 2.9e-18 66.1 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EJP61192.1 - 0.024 13.8 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PGM_PMM_III PF02880.16 EJP61192.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III THUMP PF02926.17 EJP61193.1 - 4.6e-10 39.8 0.5 9.2e-08 32.3 0.1 2.2 2 0 0 2 2 2 2 THUMP domain SGT1 PF07093.11 EJP61195.1 - 5.5e-83 279.4 22.2 2.6e-75 254.0 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein COQ9 PF08511.11 EJP61196.1 - 1.6e-29 101.5 0.1 2.6e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 COQ9 SMC_N PF02463.19 EJP61197.1 - 1.7e-22 80.0 0.0 7.8e-22 77.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP61197.1 - 8.6e-13 49.2 24.0 8.6e-13 49.2 24.0 5.3 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EJP61197.1 - 3.4e-12 46.8 8.4 3.4e-12 46.8 8.4 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EJP61197.1 - 1.4e-05 25.0 0.8 0.0011 18.9 0.1 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP61197.1 - 0.0022 17.7 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 EJP61197.1 - 0.0056 17.0 0.0 0.15 12.3 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain ABC_tran PF00005.27 EJP61197.1 - 0.24 11.9 0.1 0.24 11.9 0.1 5.0 3 2 0 3 3 3 0 ABC transporter AMP-binding PF00501.28 EJP61198.1 - 2e-78 263.9 0.0 3.4e-78 263.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EJP61198.1 - 1.2e-74 251.2 0.0 2.4e-74 250.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EJP61198.1 - 3.1e-67 227.2 0.0 4.7e-67 226.6 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 EJP61198.1 - 3.9e-56 190.5 0.0 6e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EJP61198.1 - 3.9e-50 170.3 0.1 3e-49 167.4 0.0 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EJP61198.1 - 2.2e-46 158.9 0.5 4.8e-46 157.7 0.5 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EJP61198.1 - 3.9e-30 104.9 0.0 9.6e-30 103.6 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EJP61198.1 - 4.6e-30 104.1 0.4 4.8e-29 100.8 0.0 2.7 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EJP61198.1 - 3.6e-18 66.1 0.0 1.2e-17 64.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EJP61198.1 - 2.1e-17 63.4 0.0 3.1e-12 46.5 0.0 3.2 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EJP61198.1 - 8.9e-17 61.2 0.4 1.6e-07 31.5 0.0 3.2 3 0 0 3 3 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EJP61198.1 - 3.3e-16 59.8 0.0 9.6e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EJP61198.1 - 6.9e-13 49.1 0.0 2.5e-12 47.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP61198.1 - 4.9e-12 46.0 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP61198.1 - 1.7e-11 44.1 0.0 4.4e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EJP61198.1 - 5.9e-11 42.2 0.0 1.1e-09 38.1 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 EJP61198.1 - 7.6e-11 42.5 0.0 3.2e-10 40.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.23 EJP61198.1 - 1.5e-05 24.5 0.0 3.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 EJP61198.1 - 2e-05 23.7 0.0 4.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 EJP61198.1 - 2.2e-05 24.1 0.0 5.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 EJP61198.1 - 0.0002 20.8 0.0 0.00055 19.3 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.6 EJP61198.1 - 0.008 17.1 0.1 0.43 11.6 0.0 3.2 3 0 0 3 3 2 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 EJP61198.1 - 0.081 12.7 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Abhydrolase_6 PF12697.7 EJP61199.1 - 2e-08 35.1 0.6 2e-08 35.1 0.6 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.11 EJP61199.1 - 6.8e-05 21.8 0.0 0.00041 19.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 EJP61199.1 - 0.004 16.8 0.0 0.015 15.0 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP61199.1 - 0.14 11.4 0.1 0.33 10.2 0.1 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 EJP61200.1 - 8.3e-47 159.8 50.0 9.4e-46 156.3 50.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP61200.1 - 1.8e-15 56.8 9.9 1.8e-15 56.8 9.9 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EJP61200.1 - 9.2e-10 37.6 21.5 1.2e-09 37.2 21.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.8 EJP61200.1 - 0.37 11.0 5.8 0.41 10.9 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) OATP PF03137.20 EJP61200.1 - 6 5.0 9.5 1.7 6.9 0.2 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sacchrp_dh_NADP PF03435.18 EJP61202.1 - 2.8e-12 47.0 0.0 4.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_N PF08240.12 EJP61203.1 - 6.7e-05 22.7 1.1 0.001 18.9 0.3 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP61203.1 - 0.0024 17.9 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP61203.1 - 0.18 12.8 0.0 0.35 11.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Zn_clus PF00172.18 EJP61204.1 - 8.4e-05 22.6 8.2 0.00015 21.8 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GLEYA PF10528.9 EJP61205.1 - 9.7e-26 90.0 1.5 9.7e-26 90.0 1.5 1.8 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 EJP61205.1 - 0.00082 19.2 0.1 0.0018 18.1 0.1 1.6 1 1 0 1 1 1 1 PA14 domain SAT PF16073.5 EJP61207.1 - 1.9e-39 135.8 0.2 3.5e-39 135.0 0.2 1.3 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 EJP61207.1 - 3.8e-28 98.8 1.0 9.2e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dimer_Tnp_hAT PF05699.14 EJP61207.1 - 5e-05 23.0 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CENP-F_leu_zip PF10473.9 EJP61208.1 - 0.0022 18.0 10.3 0.0028 17.7 10.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EJP61208.1 - 0.018 15.1 3.0 0.018 15.1 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EJP61208.1 - 0.045 13.0 6.2 0.055 12.7 6.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Helo_like_N PF17111.5 EJP61208.1 - 0.046 13.1 5.7 0.023 14.1 1.8 2.0 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Atg14 PF10186.9 EJP61208.1 - 0.055 12.5 9.2 0.06 12.4 9.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LNP1 PF15419.6 EJP61208.1 - 0.18 12.0 7.8 0.046 13.9 4.4 1.7 1 1 0 1 1 1 0 Leukemia NUP98 fusion partner 1 ArlS_N PF18719.1 EJP61208.1 - 0.3 11.3 6.2 4.8 7.4 6.2 2.1 1 1 0 1 1 1 0 ArlS sensor domain PRKG1_interact PF15898.5 EJP61208.1 - 0.48 11.3 16.3 0.097 13.6 8.3 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 EJP61208.1 - 0.6 10.6 20.3 0.12 12.8 1.6 2.7 2 1 0 2 2 2 0 Cell division protein ZapB USP8_interact PF08941.10 EJP61208.1 - 1.1 9.1 10.3 1.1 9.1 7.9 1.9 1 1 1 2 2 2 0 USP8 interacting GAS PF13851.6 EJP61208.1 - 1.9 7.8 14.8 1.3 8.3 10.4 2.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TRAF_BIRC3_bd PF16673.5 EJP61208.1 - 3.7 7.4 11.2 0.57 10.0 3.5 2.7 1 1 2 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain HIP1_clath_bdg PF16515.5 EJP61208.1 - 3.9 8.2 16.4 1.9 9.1 10.0 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pkinase PF00069.25 EJP61209.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Patatin PF01734.22 EJP61212.1 - 6.4e-23 82.0 0.8 7.9e-23 81.7 0.8 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase SecD_SecF PF02355.16 EJP61212.1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein export membrane protein CAGE1 PF15066.6 EJP61213.1 - 0.0026 16.5 3.6 0.0032 16.2 3.6 1.0 1 0 0 1 1 1 1 Cancer-associated gene protein 1 family Hexapep PF00132.24 EJP61218.1 - 3.9e-11 42.2 13.5 1.1e-06 28.1 3.4 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EJP61218.1 - 1.3e-08 34.4 11.7 3e-06 26.9 3.3 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 EJP61218.1 - 2.9e-08 33.7 10.0 7.7e-08 32.3 10.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 EJP61218.1 - 0.00034 20.8 0.5 0.0008 19.6 0.0 1.8 2 0 0 2 2 2 1 Maltose acetyltransferase TPR_12 PF13424.6 EJP61219.1 - 1.7e-35 121.2 23.7 2e-11 44.0 3.6 5.5 5 1 1 6 6 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EJP61219.1 - 8.5e-24 82.7 27.3 0.00014 21.6 1.1 9.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP61219.1 - 3.5e-20 72.7 15.2 1.5e-08 34.4 0.1 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_7 PF13176.6 EJP61219.1 - 1.9e-14 52.5 23.9 0.00012 21.9 0.2 8.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 EJP61219.1 - 3e-14 51.9 28.9 0.0038 17.2 0.2 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EJP61219.1 - 2.1e-13 49.5 26.1 0.0047 16.7 0.3 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EJP61219.1 - 3.3e-11 43.7 20.7 0.0073 16.9 2.9 7.0 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EJP61219.1 - 2.5e-10 39.7 21.9 0.005 17.0 0.3 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP61219.1 - 6e-08 32.9 25.2 0.49 11.4 0.0 8.1 7 2 2 9 9 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 EJP61219.1 - 3.5e-07 30.2 16.0 0.084 13.5 0.1 7.4 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_3 PF07720.12 EJP61219.1 - 1.3e-05 25.0 7.8 0.33 11.0 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 EJP61219.1 - 4.5e-05 23.4 1.1 9 6.8 0.0 5.5 5 0 0 5 5 5 0 PPR repeat TPR_21 PF09976.9 EJP61219.1 - 0.0043 16.8 15.4 1.7 8.3 4.1 5.0 2 2 2 4 4 4 1 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 EJP61219.1 - 0.0055 17.0 14.2 5.2 7.7 0.6 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP61219.1 - 0.018 15.3 8.0 11 6.3 0.6 4.7 2 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EJP61219.1 - 0.023 15.2 20.3 1.6 9.3 1.7 6.0 3 2 4 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 EJP61219.1 - 0.065 12.9 10.2 4.3 7.1 0.4 6.0 7 0 0 7 7 7 0 TPR repeat Sec16_C PF12931.7 EJP61219.1 - 0.093 12.4 0.6 20 4.7 0.0 3.4 2 2 2 4 4 4 0 Sec23-binding domain of Sec16 DUF4810 PF16068.5 EJP61219.1 - 0.17 12.4 0.1 0.17 12.4 0.1 3.6 5 0 0 5 5 4 0 Domain of unknown function (DUF4810) Peripla_BP_2 PF01497.18 EJP61219.1 - 0.5 9.9 1.8 9 5.8 0.0 3.1 2 1 1 3 3 3 0 Periplasmic binding protein Mad3_BUB1_I PF08311.12 EJP61219.1 - 1.3 9.0 6.7 19 5.2 0.1 4.5 5 1 0 5 5 4 0 Mad3/BUB1 homology region 1 Ank_4 PF13637.6 EJP61221.1 - 1.8e-07 31.6 0.6 1.5e-05 25.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP61221.1 - 2.3e-07 31.3 0.0 9.2e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) NACHT PF05729.12 EJP61221.1 - 8.7e-07 29.0 0.0 2.3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 EJP61221.1 - 7e-06 26.8 0.0 2e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_3 PF13606.6 EJP61221.1 - 7.6e-06 25.9 0.0 0.00034 20.8 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EJP61221.1 - 0.00014 22.2 0.1 0.0021 18.4 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EJP61221.1 - 0.00016 21.9 0.0 0.00064 20.0 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 EJP61221.1 - 0.00017 22.0 0.0 0.001 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.14 EJP61221.1 - 0.0071 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 EJP61221.1 - 0.026 14.6 0.1 9.6 6.2 0.0 2.7 3 0 0 3 3 3 0 Thioesterase domain AAA_29 PF13555.6 EJP61221.1 - 0.045 13.5 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP61221.1 - 0.059 13.7 0.0 0.23 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EJP61221.1 - 0.091 13.2 0.0 0.56 10.6 0.0 2.3 3 0 0 3 3 2 0 RNA helicase KAP_NTPase PF07693.14 EJP61221.1 - 0.12 11.5 0.0 20 4.3 0.0 2.6 3 0 0 3 3 3 0 KAP family P-loop domain DUF983 PF06170.12 EJP61222.1 - 0.12 12.8 0.5 0.22 12.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF983) PsbI PF02532.14 EJP61222.1 - 0.33 10.9 1.4 0.68 9.9 1.4 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Glyco_transf_34 PF05637.12 EJP61224.1 - 6.2e-12 45.7 0.0 1.1e-10 41.7 0.0 2.3 1 1 1 2 2 2 1 galactosyl transferase GMA12/MNN10 family tRNA-synt_1c PF00749.21 EJP61224.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Myb_DNA-binding PF00249.31 EJP61227.1 - 0.065 13.4 5.7 0.11 12.8 1.3 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-H2C2_2 PF13465.6 EJP61229.1 - 0.0001 22.6 18.4 0.00011 22.5 7.1 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 EJP61229.1 - 0.0012 19.2 1.0 0.0023 18.2 1.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EJP61229.1 - 0.0076 17.0 18.9 0.11 13.4 7.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 EJP61229.1 - 0.029 14.4 3.0 0.059 13.3 3.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf_UBZ PF18439.1 EJP61229.1 - 0.085 12.5 1.1 5.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 EJP61229.1 - 0.32 11.6 18.8 1.5 9.4 2.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 EJP61229.1 - 1.2 9.5 13.2 0.05 13.9 7.6 1.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 EJP61229.1 - 3.7 7.6 9.5 2.1 8.3 2.8 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 EJP61229.1 - 4 8.0 14.3 7.4 7.1 5.0 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Aminotran_3 PF00202.21 EJP61233.1 - 2.5e-67 227.3 0.0 1.2e-65 221.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III RVT_1 PF00078.27 EJP61234.1 - 1.8e-29 102.9 0.0 2.9e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EJP61234.1 - 1.2e-16 60.6 0.4 3.7e-16 59.1 0.4 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BAH PF01426.18 EJP61234.1 - 0.00023 21.0 0.1 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 BAH domain RVT_3 PF13456.6 EJP61234.1 - 0.0017 18.1 0.0 0.0047 16.7 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Exo_endo_phos PF03372.23 EJP61234.1 - 0.015 14.9 0.2 0.052 13.1 0.1 1.9 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family SCAB-Ig PF16709.5 EJP61234.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein Peptidase_S8 PF00082.22 EJP61235.1 - 1.4e-26 93.4 2.3 1.6e-24 86.7 2.3 2.2 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EJP61235.1 - 1.9e-11 44.6 0.0 3.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 EJP61235.1 - 0.03 14.2 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 FlgD Ig-like domain Enterotoxin_a PF01375.17 EJP61236.1 - 4.1e-19 69.2 0.2 5.6e-18 65.5 0.2 2.3 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain NUC129 PF08157.11 EJP61237.1 - 0.17 12.3 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 NUC129 domain RVT_1 PF00078.27 EJP61239.1 - 1.6e-23 83.4 0.0 2e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CarbpepA_inh PF02977.15 EJP61240.1 - 0.0075 16.0 0.8 0.023 14.5 0.8 1.9 1 0 0 1 1 1 1 Carboxypeptidase A inhibitor Dickkopf_N PF04706.12 EJP61240.1 - 5.8 7.5 10.7 1.2 9.7 5.6 2.5 3 1 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Metal_resist PF13801.6 EJP61241.1 - 0.086 13.0 0.1 0.2 11.9 0.1 1.5 1 1 0 1 1 1 0 Heavy-metal resistance HdeA PF06411.11 EJP61241.1 - 0.13 12.5 0.7 0.2 11.9 0.7 1.5 1 1 0 1 1 1 0 HdeA/HdeB family NUC129 PF08157.11 EJP61243.1 - 0.006 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 NUC129 domain Sua5_yciO_yrdC PF01300.18 EJP61244.1 - 3.4e-11 43.0 0.0 5.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination DUF659 PF04937.15 EJP61246.1 - 0.0017 18.2 0.0 0.026 14.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Pkinase PF00069.25 EJP61248.1 - 7.8e-05 22.2 0.0 9.2e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61248.1 - 0.18 11.0 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Flavin_Reduct PF01613.18 EJP61250.1 - 1.8e-16 60.6 0.0 2.7e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EJP61250.1 - 0.17 11.6 0.1 0.71 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF447) IL13 PF03487.13 EJP61251.1 - 0.11 12.3 0.6 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 Interleukin-13 DEC-1_N PF04625.13 EJP61251.1 - 0.36 9.8 7.3 0.39 9.7 7.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Amidase PF01425.21 EJP61253.1 - 8.3e-96 321.7 0.0 1e-95 321.4 0.0 1.1 1 0 0 1 1 1 1 Amidase FMO-like PF00743.19 EJP61254.1 - 1e-24 86.9 0.5 3.7e-12 45.5 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP61254.1 - 4.4e-09 36.0 0.1 0.00016 21.1 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP61254.1 - 0.00016 21.7 0.0 0.00036 20.5 0.0 1.6 1 1 1 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EJP61254.1 - 0.00056 20.1 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP61254.1 - 0.0023 17.2 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP61254.1 - 0.0046 16.2 0.4 0.043 13.0 0.1 2.3 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EJP61254.1 - 0.066 12.4 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Peptidase_M17_N PF02789.17 EJP61254.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Lactamase_B_4 PF13691.6 EJP61256.1 - 5.8e-20 70.7 0.1 2e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EJP61256.1 - 2.8e-16 59.6 0.5 6.7e-16 58.4 0.2 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Pkinase PF00069.25 EJP61256.1 - 3.7e-08 33.1 0.0 9.4e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Lactamase_B PF00753.27 EJP61256.1 - 0.027 14.5 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 EJP61258.1 - 2.4e-51 174.7 0.0 8.8e-51 172.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61258.1 - 4.1e-19 68.9 0.0 4e-18 65.6 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP61258.1 - 0.0027 17.1 0.3 2.3 7.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.11 EJP61258.1 - 0.038 13.0 0.1 0.056 12.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EJP61258.1 - 0.063 12.9 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Mtc PF03820.17 EJP61259.1 - 1.3e-113 379.2 0.1 1.5e-113 379.0 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier GGACT PF06094.12 EJP61260.1 - 6.4e-12 46.1 0.0 9.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like UPF0262 PF06793.12 EJP61260.1 - 0.085 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) CAP_N PF01213.19 EJP61260.1 - 2.3 7.6 5.9 3.4 7.1 5.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Zn_clus PF00172.18 EJP61261.1 - 1.3e-07 31.6 10.5 2.3e-07 30.8 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 EJP61262.1 - 2.4e-06 28.3 0.9 5.5e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EJP61262.1 - 0.001 18.6 0.0 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.11 EJP61262.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 EJP61262.1 - 0.015 14.0 0.0 0.044 12.5 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EJP61262.1 - 0.023 14.6 0.0 0.071 13.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2920 PF11144.8 EJP61262.1 - 0.064 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) BAAT_C PF08840.11 EJP61262.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1577 PF07614.11 EJP61262.1 - 0.25 10.4 0.0 0.37 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) Glyco_hydro_72 PF03198.14 EJP61263.1 - 8.7e-122 406.3 0.9 1.2e-121 405.8 0.9 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EJP61263.1 - 6.6e-22 78.0 3.2 2.1e-21 76.4 3.2 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EJP61263.1 - 0.0014 17.8 0.1 0.0048 16.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF1178 PF06676.11 EJP61263.1 - 0.074 13.4 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) CH_2 PF06294.11 EJP61263.1 - 0.19 11.9 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 CH-like domain in sperm protein dCMP_cyt_deam_1 PF00383.23 EJP61265.1 - 8e-07 28.9 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EJP61265.1 - 0.00018 21.3 0.0 0.0003 20.6 0.0 1.4 1 1 0 1 1 1 1 MafB19-like deaminase tRNA_U5-meth_tr PF05958.11 EJP61266.1 - 3.5e-13 49.3 0.0 9.4e-12 44.6 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EJP61266.1 - 1.4e-06 28.0 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRAM PF01938.20 EJP61266.1 - 3e-06 27.1 0.1 0.0001 22.2 0.0 2.4 2 0 0 2 2 2 1 TRAM domain Methyltransf_31 PF13847.6 EJP61266.1 - 9.4e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP61266.1 - 0.00014 22.5 0.0 0.00035 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EJP61266.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EJP61266.1 - 0.092 13.4 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EJP61266.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Spem1 PF15670.5 EJP61266.1 - 0.16 11.5 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 UNC45-central PF11701.8 EJP61267.1 - 1.2e-51 174.7 0.0 1.3e-50 171.4 0.0 2.6 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EJP61267.1 - 0.00036 20.5 12.6 0.0016 18.4 0.0 5.8 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat Glyco_hydro_63 PF03200.16 EJP61267.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain HEAT_2 PF13646.6 EJP61267.1 - 1 9.8 16.3 2.4 8.6 0.0 5.0 6 2 1 7 7 7 0 HEAT repeats Tfb4 PF03850.14 EJP61268.1 - 1.7e-92 309.8 0.0 2e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 TerY_C PF15616.6 EJP61268.1 - 0.24 11.5 2.3 1.4 9.0 1.9 2.0 2 0 0 2 2 2 0 TerY-C metal binding domain Asparaginase_2 PF01112.18 EJP61269.1 - 3.5e-43 147.8 0.8 3.4e-27 95.3 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Filament PF00038.21 EJP61271.1 - 0.0034 17.0 11.5 0.0043 16.7 11.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein TMCO5 PF14992.6 EJP61271.1 - 0.25 10.9 11.8 0.34 10.4 11.8 1.2 1 1 0 1 1 1 0 TMCO5 family FUSC PF04632.12 EJP61271.1 - 0.94 7.9 6.1 1.1 7.7 6.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIVA PF05103.13 EJP61271.1 - 1.8 8.7 13.9 1.3 9.1 0.9 2.3 1 1 1 2 2 2 0 DivIVA protein CENP-H PF05837.12 EJP61271.1 - 4.7 7.7 12.9 0.23 11.9 4.9 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 EJP61272.1 - 0.0013 18.8 2.6 0.0019 18.3 2.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 EJP61272.1 - 0.0027 15.9 2.3 0.0035 15.6 2.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Leu_zip PF15294.6 EJP61272.1 - 0.011 15.3 0.4 0.014 14.9 0.4 1.1 1 0 0 1 1 1 0 Leucine zipper DUF3450 PF11932.8 EJP61272.1 - 0.041 13.2 0.4 0.052 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 EJP61272.1 - 0.046 14.2 5.0 0.1 13.1 5.0 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Nucleoporin_C PF03177.14 EJP61272.1 - 0.075 11.8 0.3 0.093 11.4 0.3 1.1 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal DivIC PF04977.15 EJP61272.1 - 8.5 6.2 7.9 11 5.8 0.1 2.4 1 1 1 2 2 2 0 Septum formation initiator Beach PF02138.18 EJP61273.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Beige/BEACH domain MFS_1 PF07690.16 EJP61279.1 - 6.8e-32 110.8 24.9 6.8e-32 110.8 24.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP61279.1 - 2.1e-11 43.4 0.6 2.1e-11 43.4 0.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.16 EJP61279.1 - 6.9e-06 24.6 0.0 1.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 BT1 family EHN PF06441.12 EJP61280.1 - 8.8e-37 125.8 0.1 7.1e-35 119.6 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EJP61280.1 - 1.2e-11 44.7 0.2 2.2e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP61280.1 - 0.0012 19.5 0.8 0.0038 17.9 0.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Acyl-CoA_dh_1 PF00441.24 EJP61281.1 - 5.6e-31 107.8 2.2 7.7e-31 107.3 2.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EJP61281.1 - 2.8e-21 75.5 0.1 4.8e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EJP61281.1 - 3.6e-20 72.7 0.0 1e-19 71.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EJP61281.1 - 0.0017 18.6 0.1 0.0028 17.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB PF03241.13 EJP61281.1 - 0.099 11.7 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal HpaB_N PF11794.8 EJP61281.1 - 0.24 11.0 0.4 1.1 8.9 0.4 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal MFS_1 PF07690.16 EJP61284.1 - 1.8e-34 119.2 37.4 2.3e-34 118.9 37.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3754 PF12576.8 EJP61284.1 - 0.27 11.2 3.7 0.51 10.3 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3754) LapA_dom PF06305.11 EJP61284.1 - 0.56 10.1 7.8 9.1 6.2 1.4 4.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SPT_ssu-like PF11779.8 EJP61284.1 - 1.3 8.7 6.2 2 8.1 1.0 3.4 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like MASE2 PF05230.11 EJP61284.1 - 1.5 9.0 7.2 0.31 11.1 1.0 2.7 2 0 0 2 2 2 0 MASE2 domain peroxidase PF00141.23 EJP61285.1 - 8.9e-85 284.0 0.0 1.6e-49 168.6 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Thioredoxin PF00085.20 EJP61286.1 - 2.5e-25 88.4 0.0 3.4e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EJP61286.1 - 7.4e-07 29.4 0.0 4.1e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EJP61286.1 - 1.5e-06 28.6 0.1 3.9e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EJP61286.1 - 1.5e-05 24.5 0.7 2.7e-05 23.7 0.1 1.7 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EJP61286.1 - 3.9e-05 23.6 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJP61286.1 - 9.1e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 EJP61286.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EJP61286.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 EJP61286.1 - 0.00032 20.6 0.0 0.00055 19.9 0.0 1.4 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 EJP61286.1 - 0.00043 20.4 0.1 0.0007 19.7 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_5 PF13743.6 EJP61286.1 - 0.017 14.8 0.0 0.09 12.4 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin Phosducin PF02114.16 EJP61286.1 - 0.074 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosducin DIM1 PF02966.16 EJP61286.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 ABC_membrane PF00664.23 EJP61287.1 - 3.9e-59 200.5 20.8 8e-35 120.8 6.8 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP61287.1 - 5.1e-49 166.3 0.0 5e-31 108.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP61287.1 - 5.9e-07 29.1 1.8 0.0081 15.6 0.5 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP61287.1 - 1e-05 26.2 0.3 0.013 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJP61287.1 - 0.00037 20.9 0.3 0.49 10.8 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EJP61287.1 - 0.0005 20.0 1.6 1.5 8.6 0.2 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EJP61287.1 - 0.0007 19.5 0.1 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EJP61287.1 - 0.00086 18.9 0.0 0.15 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EJP61287.1 - 0.00089 18.4 0.3 0.14 11.2 0.2 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EJP61287.1 - 0.0019 18.3 0.1 0.074 13.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EJP61287.1 - 0.0098 15.6 1.4 3 7.7 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 EJP61287.1 - 0.012 15.7 2.0 0.13 12.4 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 EJP61287.1 - 0.019 15.2 1.6 3 8.1 0.1 3.2 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EJP61287.1 - 0.033 13.9 0.3 0.76 9.5 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 EJP61287.1 - 0.065 12.9 1.2 17 5.0 0.3 3.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJP61287.1 - 0.079 12.5 0.6 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 EJP61287.1 - 0.099 12.4 0.5 20 4.9 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 EJP61287.1 - 0.12 11.6 0.6 6.5 6.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EJP61287.1 - 0.16 12.2 2.0 15 5.7 0.2 3.5 3 0 0 3 3 3 0 AAA domain Adaptin_binding PF10199.9 EJP61288.1 - 2.9e-09 37.6 7.4 8.4e-09 36.1 7.4 1.8 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Strep_SA_rep PF06696.11 EJP61288.1 - 0.057 13.4 0.8 11 6.2 0.5 2.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Homeodomain PF00046.29 EJP61289.1 - 1.3e-19 69.8 1.6 2.7e-19 68.8 1.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EJP61289.1 - 0.0033 17.3 0.3 0.0072 16.2 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain AsmA_1 PF13109.6 EJP61289.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region DUF3553 PF12073.8 EJP61289.1 - 0.18 11.6 0.2 0.45 10.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) NAM-associated PF14303.6 EJP61289.1 - 0.31 11.7 6.1 0.55 10.9 6.1 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PhoLip_ATPase_C PF16212.5 EJP61290.1 - 1.3e-69 234.7 24.9 1.3e-69 234.7 24.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EJP61290.1 - 1.6e-24 85.3 2.5 1.8e-23 82.0 0.1 2.7 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EJP61290.1 - 1.6e-12 48.2 0.2 1.2e-05 25.7 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJP61290.1 - 1.2e-11 44.5 0.0 2.8e-10 40.2 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EJP61290.1 - 4.6e-09 36.0 0.0 1.6e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EJP61290.1 - 0.00033 20.5 0.0 0.0035 17.1 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Arylsulfotrans PF05935.11 EJP61292.1 - 5.5e-15 55.2 0.0 4.5e-07 29.1 0.0 2.4 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EJP61292.1 - 3.3e-13 49.7 0.0 4.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 EJP61292.1 - 0.00012 21.7 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain HNH_2 PF13391.6 EJP61293.1 - 4.4e-10 39.6 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease PBP1_TM PF14812.6 EJP61293.1 - 1 9.8 4.6 1.8 9.0 4.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FA_hydroxylase PF04116.13 EJP61294.1 - 8.7e-21 74.7 17.3 8.7e-21 74.7 17.3 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DAO PF01266.24 EJP61296.1 - 2.4e-46 159.0 0.0 2.7e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EJP61296.1 - 0.00017 20.9 0.5 0.00031 20.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP61296.1 - 0.00026 20.3 2.5 0.0013 18.0 1.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP61296.1 - 0.0036 16.4 1.2 0.0081 15.3 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 EJP61296.1 - 0.0093 15.9 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EJP61296.1 - 0.013 14.9 0.4 0.019 14.3 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP61296.1 - 0.02 14.0 3.0 0.68 8.9 3.0 2.1 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EJP61296.1 - 0.021 13.5 1.0 0.69 8.5 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_2 PF03446.15 EJP61296.1 - 0.021 15.0 0.2 0.048 13.8 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 EJP61296.1 - 0.1 11.9 0.2 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 EJP61296.1 - 0.17 12.1 0.4 0.38 11.0 0.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Optomotor-blind PF11078.8 EJP61297.1 - 0.011 16.3 3.6 9.8 6.8 0.1 3.4 3 0 0 3 3 3 0 Optomotor-blind protein N-terminal region p450 PF00067.22 EJP61298.1 - 5.6e-60 203.4 0.0 8.4e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EJP61299.1 - 6.5e-19 68.3 0.0 1.5e-08 34.3 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61299.1 - 5.6e-05 22.5 0.7 0.59 9.4 0.2 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EJP61299.1 - 0.0015 17.9 0.0 0.03 13.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like DAGAT PF03982.13 EJP61300.1 - 4.8e-91 304.7 0.0 6.9e-91 304.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Velvet PF11754.8 EJP61301.1 - 4.8e-88 295.3 15.3 5.7e-87 291.8 0.0 2.2 2 0 0 2 2 2 1 Velvet factor KOG2701 PF09762.9 EJP61301.1 - 0.11 12.8 4.1 0.17 12.1 4.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Sarcoglycan_2 PF05510.13 EJP61301.1 - 0.61 8.8 3.9 1 8.1 3.9 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Presenilin PF01080.17 EJP61301.1 - 0.89 8.2 6.0 1.2 7.8 6.0 1.2 1 0 0 1 1 1 0 Presenilin Endostatin PF06482.11 EJP61301.1 - 1.5 8.2 10.3 3.2 7.1 10.3 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4770 PF15994.5 EJP61301.1 - 1.9 8.7 8.8 3.2 8.0 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TERB2 PF15101.6 EJP61301.1 - 2.5 8.1 11.8 4.6 7.2 11.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CPSF100_C PF13299.6 EJP61301.1 - 3 8.0 4.7 5.4 7.2 4.7 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PAT1 PF09770.9 EJP61301.1 - 3.5 5.8 20.4 4.9 5.3 20.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4551 PF15087.6 EJP61301.1 - 4.7 5.9 10.9 7 5.4 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V_ATPase_I PF01496.19 EJP61301.1 - 6.5 4.5 6.7 8.7 4.1 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NFACT-C PF11923.8 EJP61303.1 - 3.3e-37 126.6 0.1 3.3e-37 126.6 0.1 3.1 3 0 0 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 EJP61303.1 - 6.5e-28 97.7 4.5 2.4e-21 76.0 0.0 2.4 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EJP61303.1 - 3e-26 92.2 0.0 7.6e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain Annexin PF00191.20 EJP61304.1 - 3.6e-20 71.8 1.4 0.00016 21.7 0.1 4.5 4 0 0 4 4 4 4 Annexin RIBIOP_C PF04950.12 EJP61304.1 - 1.8 7.9 5.1 0.91 8.9 2.5 1.8 2 0 0 2 2 2 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Methyltransf_32 PF13679.6 EJP61305.1 - 0.037 14.0 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EJP61306.1 - 3.4e-23 82.3 0.0 6.9e-23 81.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP61306.1 - 3.3e-13 50.1 0.0 9.9e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP61306.1 - 2.4e-12 47.3 0.0 9.1e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP61306.1 - 3.6e-09 36.6 0.0 0.0002 21.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EJP61306.1 - 5.7e-08 33.4 0.0 4.8e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EJP61306.1 - 0.00063 19.2 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EJP61306.1 - 0.014 14.9 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EJP61306.1 - 0.18 11.1 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_2 PF00891.18 EJP61307.1 - 1.9e-23 82.9 0.0 3.4e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 EJP61307.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ketoacyl-synt PF00109.26 EJP61308.1 - 7.2e-74 248.6 0.0 1.3e-73 247.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EJP61308.1 - 2.2e-50 171.1 1.2 5.1e-50 169.9 0.2 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EJP61308.1 - 4.1e-47 160.9 0.0 6.4e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EJP61308.1 - 9.6e-47 160.0 0.0 1.7e-46 159.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP61308.1 - 3.5e-37 127.0 0.1 3.1e-36 124.0 0.0 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EJP61308.1 - 5.4e-17 62.3 0.0 1.3e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EJP61308.1 - 2e-13 50.2 0.9 1.6e-11 44.1 0.2 2.7 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP61308.1 - 4.2e-09 36.3 0.6 1.4e-08 34.6 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 EJP61308.1 - 3.9e-06 26.9 0.0 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EJP61308.1 - 0.0054 17.0 0.0 0.022 15.1 0.0 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site ELFV_dehydrog PF00208.21 EJP61308.1 - 0.017 14.8 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sacchrp_dh_NADP PF03435.18 EJP61308.1 - 0.023 15.0 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thiolase_N PF00108.23 EJP61308.1 - 0.036 13.4 0.2 0.098 12.0 0.2 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain MFS_1 PF07690.16 EJP61309.1 - 1.2e-22 80.3 42.4 2.7e-14 52.9 34.7 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP61309.1 - 4e-09 35.4 21.6 5.5e-09 35.0 21.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Dabb PF07876.12 EJP61310.1 - 7.2e-10 39.4 0.0 8.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain YIF1 PF03878.15 EJP61312.1 - 3.3e-99 331.3 0.8 5.5e-99 330.5 0.8 1.3 1 0 0 1 1 1 1 YIF1 Mpv17_PMP22 PF04117.12 EJP61312.1 - 1.3e-11 44.5 1.3 1.3e-11 44.5 1.3 2.5 2 0 0 2 2 2 1 Mpv17 / PMP22 family Yip1 PF04893.17 EJP61312.1 - 2.1 8.1 19.1 0.012 15.3 6.2 3.0 3 0 0 3 3 3 0 Yip1 domain SRP-alpha_N PF04086.13 EJP61313.1 - 2.2e-77 260.9 0.2 3e-77 260.4 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EJP61313.1 - 2.8e-53 180.5 0.2 5.5e-53 179.5 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EJP61313.1 - 6.9e-07 29.4 0.0 2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 EJP61313.1 - 0.00014 21.6 3.1 0.00045 20.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EJP61313.1 - 0.00046 19.3 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 EJP61313.1 - 0.0016 18.9 1.1 0.003 18.0 0.1 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EJP61313.1 - 0.0023 18.3 0.5 0.18 12.1 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain cobW PF02492.19 EJP61313.1 - 0.0024 17.5 0.2 0.0044 16.6 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EJP61313.1 - 0.0058 16.8 0.1 0.17 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EJP61313.1 - 0.0076 15.8 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EJP61313.1 - 0.021 14.5 0.4 0.08 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EJP61313.1 - 0.026 15.1 0.3 0.15 12.6 0.0 2.3 2 1 0 2 2 2 0 ABC transporter CbiA PF01656.23 EJP61313.1 - 0.037 14.1 1.0 2 8.5 0.1 2.7 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 EJP61313.1 - 0.043 13.9 0.2 0.2 11.7 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 EJP61313.1 - 0.069 13.1 1.6 1.9 8.3 0.0 2.6 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 EJP61313.1 - 0.16 11.9 0.1 2.7 7.9 0.0 2.7 3 0 0 3 3 3 0 NACHT domain PAM2 PF07145.15 EJP61314.1 - 0.14 11.9 3.2 0.84 9.5 1.1 2.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Mid2 PF04478.12 EJP61315.1 - 5.9e-06 26.2 0.9 5.9e-06 26.2 0.9 2.7 3 2 1 4 4 4 1 Mid2 like cell wall stress sensor Podoplanin PF05808.11 EJP61315.1 - 0.01 16.0 9.2 0.01 16.0 9.2 2.4 1 1 1 2 2 2 0 Podoplanin Hamartin PF04388.12 EJP61315.1 - 0.65 8.6 25.4 0.74 8.4 25.4 1.2 1 0 0 1 1 1 0 Hamartin protein PARM PF17061.5 EJP61315.1 - 2.7 8.1 52.8 0.24 11.5 48.4 1.4 2 0 0 2 2 2 0 PARM Utp14 PF04615.13 EJP61315.1 - 6.2 5.3 16.2 9.6 4.6 16.2 1.2 1 0 0 1 1 1 0 Utp14 protein DUF4834 PF16118.5 EJP61315.1 - 8.3 7.4 11.6 1.8e+03 -0.1 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Pil1 PF13805.6 EJP61316.1 - 9.2e-109 363.0 4.7 1.2e-108 362.7 4.7 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Pyrophosphatase PF00719.19 EJP61317.1 - 1.9e-57 193.6 0.0 2.5e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Ashwin PF15323.6 EJP61317.1 - 0.061 13.3 1.0 0.09 12.8 1.0 1.2 1 0 0 1 1 1 0 Developmental protein TMEM171 PF15471.6 EJP61317.1 - 2.9 6.8 6.7 4.4 6.2 6.7 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 MRP_L53 PF10780.9 EJP61318.1 - 3.5e-22 78.3 2.6 3.7e-22 78.2 0.9 1.8 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.13 EJP61319.1 - 4.1e-14 52.3 2.1 1.3e-13 50.7 0.0 2.7 3 0 0 3 3 3 1 Sec20 Ribosomal_S5 PF00333.20 EJP61319.1 - 0.0014 18.5 0.8 0.37 10.8 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein S5, N-terminal domain Merozoite_SPAM PF07133.11 EJP61319.1 - 0.29 11.1 11.0 0.56 10.2 11.0 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) BcrAD_BadFG PF01869.20 EJP61319.1 - 0.35 10.3 4.1 0.16 11.5 1.3 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family AIF_C PF14721.6 EJP61319.1 - 1.1 9.6 6.9 0.12 12.8 2.1 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Aldolase_II PF00596.21 EJP61320.1 - 1.3e-43 149.2 0.0 1.9e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain zf-H2C2_2 PF13465.6 EJP61321.1 - 1e-06 28.9 11.1 5.4e-06 26.6 1.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EJP61321.1 - 8.6e-06 25.6 1.6 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP61321.1 - 1e-05 25.7 0.5 1e-05 25.7 0.5 3.1 2 1 0 2 2 2 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 EJP61321.1 - 0.00012 22.7 5.7 0.26 12.0 0.0 2.8 2 1 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EJP61321.1 - 0.00029 21.4 5.0 0.0041 17.8 0.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EJP61321.1 - 0.15 11.8 1.4 0.59 9.9 0.1 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 EJP61321.1 - 0.19 11.5 2.8 0.65 9.8 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 EJP61321.1 - 0.2 12.0 1.5 2.6 8.4 0.3 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sina PF03145.16 EJP61321.1 - 2.3 8.1 7.5 5.7 6.8 2.3 2.2 1 1 1 2 2 2 0 Seven in absentia protein family DAHP_synth_1 PF00793.20 EJP61322.1 - 3.4e-100 334.5 0.0 4.2e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Fungal_trans PF04082.18 EJP61323.1 - 0.028 13.4 0.1 0.13 11.3 0.0 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain K_channel_TID PF07941.11 EJP61323.1 - 7.7 7.0 23.7 2.6 8.6 3.1 3.6 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain MFS_1 PF07690.16 EJP61324.1 - 7.6e-43 146.8 48.8 7.6e-43 146.8 48.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP61324.1 - 3.8e-14 52.0 30.1 6.8e-14 51.2 30.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EJP61324.1 - 1.2e-07 31.0 9.9 1.2e-07 31.0 9.9 3.3 2 2 0 2 2 2 1 Sugar (and other) transporter Tnp_P_element_C PF12596.8 EJP61324.1 - 0.07 13.7 0.5 1.1 9.9 0.7 2.1 2 0 0 2 2 2 0 87kDa Transposase p450 PF00067.22 EJP61325.1 - 1.2e-30 106.7 0.0 2.2e-30 105.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Mucin PF01456.17 EJP61327.1 - 0.0035 17.4 4.4 0.0035 17.4 4.4 3.0 3 0 0 3 3 3 1 Mucin-like glycoprotein Pilin_N PF07790.11 EJP61327.1 - 0.13 13.2 0.6 0.45 11.5 0.6 2.0 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Fungal_trans_2 PF11951.8 EJP61328.1 - 1.7e-45 155.5 0.1 2.5e-45 154.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.21 EJP61329.1 - 5.3e-51 173.0 0.1 1.1e-50 172.0 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EJP61329.1 - 7.4e-12 45.6 0.0 0.0013 19.5 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP61329.1 - 2.8e-05 24.3 0.0 0.046 14.0 0.0 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP61329.1 - 0.017 14.1 0.4 0.55 9.1 0.1 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Far-17a_AIG1 PF04750.14 EJP61330.1 - 6.8e-40 136.5 15.5 7.8e-40 136.4 15.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Vma12 PF11712.8 EJP61330.1 - 9.4 6.3 9.5 0.11 12.6 0.9 2.0 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ApbA_C PF08546.11 EJP61331.1 - 3.2e-25 88.8 0.0 7e-25 87.6 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EJP61331.1 - 4.6e-14 52.3 0.0 7.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FMN_dh PF01070.18 EJP61331.1 - 0.00018 20.7 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AMP-binding PF00501.28 EJP61332.1 - 8.4e-137 456.2 0.0 7.5e-69 232.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EJP61332.1 - 1.2e-130 436.3 0.0 1.7e-79 267.7 0.0 3.3 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EJP61332.1 - 3.2e-33 113.9 0.1 1.5e-11 44.5 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP61332.1 - 4.1e-12 46.9 5.3 0.0037 18.2 3.4 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 EJP61332.1 - 7.8e-05 23.3 0.0 0.00068 20.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP61332.1 - 0.00075 20.2 0.0 0.002 18.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP61332.1 - 0.0039 17.0 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP61332.1 - 0.011 15.6 0.0 0.035 13.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EJP61332.1 - 0.028 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_20 PF12147.8 EJP61332.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase SOG2 PF10428.9 EJP61333.1 - 4.2 6.5 22.9 5.1 6.2 22.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Peroxin-3 PF04882.12 EJP61333.1 - 6.3 5.7 9.8 6.4 5.6 9.8 1.3 1 0 0 1 1 1 0 Peroxin-3 Apt1 PF10351.9 EJP61333.1 - 7.7 5.2 15.1 10 4.9 15.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 EJP61333.1 - 9.8 6.0 15.2 11 5.8 15.2 1.1 1 0 0 1 1 1 0 SPX domain Calreticulin PF00262.18 EJP61334.1 - 6.5e-167 555.0 19.3 6.5e-167 555.0 19.3 1.3 2 0 0 2 2 2 1 Calreticulin family DUF1911 PF08929.10 EJP61334.1 - 0.057 14.2 0.1 0.14 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Aldedh PF00171.22 EJP61335.1 - 8.6e-135 449.8 0.1 8.6e-135 449.8 0.1 1.5 2 0 0 2 2 2 1 Aldehyde dehydrogenase family RRF PF01765.19 EJP61335.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosome recycling factor DUF2464 PF10240.9 EJP61335.1 - 0.21 11.1 1.4 0.34 10.5 1.4 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 F-box PF00646.33 EJP61336.1 - 0.0018 18.1 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain Sporozoite_P67 PF05642.11 EJP61336.1 - 0.44 8.6 2.7 0.58 8.2 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAD_binding_3 PF01494.19 EJP61337.1 - 4.7e-45 154.3 0.0 5.7e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EJP61337.1 - 3.3e-33 115.1 0.0 5.8e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 EJP61337.1 - 0.081 12.0 0.0 0.29 10.1 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase adh_short PF00106.25 EJP61338.1 - 1.8e-36 125.4 0.1 2.5e-36 125.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP61338.1 - 4.7e-25 88.5 0.1 6.2e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP61338.1 - 3.5e-06 27.1 1.9 5.1e-05 23.3 1.9 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP61338.1 - 9.7e-05 21.9 0.1 0.00029 20.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Indigoidine_A PF04227.12 EJP61339.1 - 9.5e-109 363.2 0.5 1.3e-108 362.8 0.5 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EJP61339.1 - 3.2e-21 75.9 0.0 1.8e-12 47.2 0.0 2.7 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HTH_DeoR PF08220.12 EJP61339.1 - 0.31 10.8 1.0 3 7.7 0.2 2.8 2 1 1 3 3 3 0 DeoR-like helix-turn-helix domain ANAPC4_WD40 PF12894.7 EJP61340.1 - 4.7e-09 36.4 0.0 0.028 14.7 0.0 5.0 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJP61340.1 - 2.5e-08 34.4 0.0 0.32 11.9 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 EJP61340.1 - 0.007 16.3 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat SLD5_C PF16922.5 EJP61341.1 - 3.5e-11 43.1 0.0 5.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EJP61341.1 - 8.6e-08 32.6 0.5 2.8e-07 31.0 0.3 1.9 1 1 0 2 2 2 1 GINS complex protein CorA PF01544.18 EJP61343.1 - 3.1e-12 46.4 1.4 9.9e-12 44.8 1.4 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FliJ PF02050.16 EJP61343.1 - 0.073 13.3 0.3 29 4.9 0.0 3.6 3 0 0 3 3 3 0 Flagellar FliJ protein Acyl_transf_3 PF01757.22 EJP61343.1 - 0.19 10.8 1.0 0.32 10.0 1.0 1.2 1 0 0 1 1 1 0 Acyltransferase family PPTA PF01239.22 EJP61344.1 - 3.8e-13 48.7 0.0 1e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat AAR2 PF05282.11 EJP61344.1 - 0.16 11.3 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 AAR2 protein NUP214 PF16755.5 EJP61346.1 - 0.06 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 JIP_LZII PF16471.5 EJP61348.1 - 2.2 8.5 14.5 3.2 8.0 2.2 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II COG5 PF10392.9 EJP61348.1 - 2.6 8.2 11.6 0.046 13.9 4.1 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 RAI16-like PF10257.9 EJP61349.1 - 2.9e-72 243.5 0.0 4.2e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Adeno_52K PF03052.15 EJP61349.1 - 0.11 11.9 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa CAP_N PF01213.19 EJP61349.1 - 3.6 7.0 4.7 1.9 7.9 1.7 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal LAT PF15234.6 EJP61349.1 - 4.8 6.9 11.0 0.46 10.2 0.5 3.1 3 0 0 3 3 3 0 Linker for activation of T-cells Glyco_hydro_16 PF00722.21 EJP61350.1 - 1.2e-28 99.7 0.1 8.7e-26 90.5 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 TPR_12 PF13424.6 EJP61351.1 - 3.5e-19 68.9 13.7 1.1e-09 38.4 2.0 4.9 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EJP61351.1 - 6.5e-11 41.6 0.4 0.013 15.3 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP61351.1 - 9.1e-10 37.9 3.6 0.22 11.8 0.3 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EJP61351.1 - 5.6e-08 32.4 10.5 0.019 14.8 0.3 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP61351.1 - 3.3e-07 29.9 8.8 0.25 11.4 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 EJP61351.1 - 6.9e-06 25.5 0.1 1.6e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily SPO22 PF08631.10 EJP61351.1 - 5.9e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like AAA_16 PF13191.6 EJP61351.1 - 8.3e-05 23.0 0.0 0.00083 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_16 PF13432.6 EJP61351.1 - 9.3e-05 23.0 8.6 4.8 7.9 0.1 6.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP61351.1 - 9.5e-05 22.8 1.6 1.9 9.0 0.6 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EJP61351.1 - 0.00038 20.8 2.1 4 8.3 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EJP61351.1 - 0.00048 20.7 9.5 30 5.8 0.1 6.6 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJP61351.1 - 0.00059 19.8 0.3 73 4.0 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJP61351.1 - 0.0017 18.9 6.3 11 6.9 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat NB-ARC PF00931.22 EJP61351.1 - 0.002 17.4 0.0 0.11 11.6 0.0 2.4 1 1 1 2 2 2 1 NB-ARC domain DsbD_2 PF13386.6 EJP61351.1 - 0.0073 16.3 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Paf67 PF10255.9 EJP61351.1 - 0.12 11.4 1.2 0.33 9.9 0.5 2.0 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 DUF3856 PF12968.7 EJP61351.1 - 0.12 12.4 0.2 0.49 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) ATPase_2 PF01637.18 EJP61351.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Prothymosin PF03247.14 EJP61352.1 - 0.019 15.4 0.1 0.032 14.7 0.1 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family zf-C2H2_aberr PF17017.5 EJP61352.1 - 0.082 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EJP61352.1 - 0.88 10.6 2.9 39 5.5 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_S8 PF00082.22 EJP61353.1 - 6.2e-38 130.7 1.6 9.6e-38 130.1 1.6 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EJP61353.1 - 2.4e-25 88.4 0.6 5.4e-25 87.2 0.6 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 EJP61353.1 - 0.00081 20.1 0.1 0.0019 18.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 EJP61353.1 - 0.16 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal of Subtilase family PX PF00787.24 EJP61354.1 - 2.1e-19 69.6 0.6 5.5e-19 68.2 0.1 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EJP61354.1 - 4.6e-08 32.9 7.4 5.5e-06 26.1 0.6 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EJP61354.1 - 0.0019 17.9 8.3 0.014 15.1 8.3 2.0 1 1 0 1 1 1 1 BAR domain AlkA_N PF06029.11 EJP61354.1 - 0.0088 16.3 0.2 0.027 14.7 0.2 1.9 1 0 0 1 1 1 1 AlkA N-terminal domain Occludin_ELL PF07303.13 EJP61354.1 - 0.025 15.3 2.2 0.11 13.2 0.0 3.0 3 1 1 4 4 4 0 Occludin homology domain BAR_3 PF16746.5 EJP61354.1 - 0.28 10.9 3.6 0.52 10.0 0.1 2.2 2 1 0 2 2 2 0 BAR domain of APPL family Spc7 PF08317.11 EJP61354.1 - 5.6 5.7 10.1 0.15 10.9 2.8 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 EJP61354.1 - 6.2 6.9 10.3 5.8 7.0 0.0 3.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 EJP61354.1 - 7 6.7 9.0 0.32 11.0 0.4 2.7 3 0 0 3 3 3 0 Prefoldin subunit LETM1 PF07766.13 EJP61355.1 - 1.4e-104 349.2 1.8 3.2e-104 348.0 1.8 1.6 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 EJP61355.1 - 0.00066 19.4 0.0 0.02 14.7 0.0 2.7 2 0 0 2 2 2 1 SAP domain Amidinotransf PF02274.17 EJP61356.1 - 8.1e-08 31.7 0.0 0.0007 18.8 0.0 2.7 2 1 0 2 2 2 2 Amidinotransferase ADK PF00406.22 EJP61357.1 - 8.7e-35 120.0 0.0 1e-18 67.8 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EJP61357.1 - 8.3e-16 57.7 0.0 1.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EJP61357.1 - 1.6e-12 48.0 0.0 2.4e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EJP61357.1 - 0.00099 19.7 0.0 0.0048 17.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EJP61357.1 - 0.0058 16.8 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EJP61357.1 - 0.055 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 EJP61357.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF89 PF01937.19 EJP61359.1 - 2.9e-127 424.4 0.0 3.4e-127 424.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Tail_spike_N PF18668.1 EJP61360.1 - 0.76 9.7 6.9 0.96 9.3 3.3 2.9 2 0 0 2 2 2 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain Sod_Fe_C PF02777.18 EJP61361.1 - 2.5e-34 117.5 0.3 4.1e-34 116.8 0.1 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EJP61361.1 - 2.5e-31 108.0 3.4 3.7e-31 107.4 1.5 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HSP70 PF00012.20 EJP61364.1 - 0.053 11.7 0.0 0.081 11.1 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF2958 PF11171.8 EJP61364.1 - 0.1 12.9 0.0 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2958) BcrAD_BadFG PF01869.20 EJP61364.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family LAT PF15234.6 EJP61365.1 - 6.5e-05 22.8 9.6 7.5e-05 22.6 9.6 1.0 1 0 0 1 1 1 1 Linker for activation of T-cells Shisa PF13908.6 EJP61365.1 - 0.1 12.8 0.9 0.13 12.5 0.9 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator FAP PF07174.11 EJP61365.1 - 0.53 9.7 21.4 0.54 9.7 21.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Glyco_transf_20 PF00982.21 EJP61368.1 - 6.1e-44 150.5 0.0 7.1e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Lir1 PF07207.11 EJP61371.1 - 0.017 15.4 4.1 0.037 14.3 4.1 1.5 1 0 0 1 1 1 0 Light regulated protein Lir1 Abhydrolase_6 PF12697.7 EJP61372.1 - 0.00095 19.8 0.1 0.0029 18.2 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP61372.1 - 0.03 14.0 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EJP61372.1 - 0.033 14.0 0.1 0.054 13.3 0.1 1.2 1 0 0 1 1 1 0 Serine hydrolase Luteo_Vpg PF01659.16 EJP61373.1 - 0.016 15.5 1.2 0.024 15.0 1.1 1.5 1 1 0 1 1 1 0 Luteovirus putative VPg genome linked protein FAD_binding_8 PF08022.12 EJP61376.1 - 3.4e-10 40.0 0.0 5.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EJP61376.1 - 7.8e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Pkinase PF00069.25 EJP61377.1 - 9.9e-05 21.8 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61377.1 - 0.0076 15.6 0.0 0.014 14.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3723 PF12520.8 EJP61378.1 - 3.7e-173 576.8 0.3 3.7e-173 576.8 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) MerR-DNA-bind PF09278.11 EJP61378.1 - 0.0078 16.7 0.4 0.0078 16.7 0.4 4.3 3 1 0 3 3 3 1 MerR, DNA binding Atg14 PF10186.9 EJP61378.1 - 0.64 9.0 7.5 3.3 6.7 7.8 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 WD40 PF00400.32 EJP61379.1 - 6.7e-80 260.9 47.6 5.6e-10 39.7 0.3 10.9 9 1 1 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP61379.1 - 5.7e-25 87.4 6.8 6.6e-07 29.5 0.1 6.3 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP61379.1 - 5.3e-10 38.6 25.5 0.093 11.4 0.4 7.5 1 1 5 7 7 7 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EJP61379.1 - 4.4e-07 29.2 17.7 0.66 8.9 0.3 6.5 2 1 5 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EJP61379.1 - 2.6e-05 23.7 0.3 1.1 8.6 0.0 4.5 2 2 2 5 5 5 2 WD40-like domain AAA_16 PF13191.6 EJP61379.1 - 0.00021 21.7 0.0 0.0018 18.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EJP61379.1 - 0.0007 19.6 0.2 0.06 13.3 0.5 2.9 1 1 1 2 2 2 2 NACHT domain RNA_helicase PF00910.22 EJP61379.1 - 0.0033 17.8 0.0 0.0089 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Helo_like_N PF17111.5 EJP61379.1 - 0.0039 16.6 1.1 0.0098 15.3 1.1 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_18 PF13238.6 EJP61379.1 - 0.0063 17.0 0.0 0.054 14.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 EJP61379.1 - 0.019 14.2 0.0 0.047 12.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 EJP61379.1 - 0.023 14.8 1.3 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain PSD5 PF07637.11 EJP61379.1 - 0.071 13.5 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) PIF1 PF05970.14 EJP61379.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase HET PF06985.11 EJP61380.1 - 7.3e-30 104.2 0.0 1.6e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4803 PF16061.5 EJP61381.1 - 0.054 12.9 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) Dimer_Tnp_hAT PF05699.14 EJP61382.1 - 3.6e-20 71.5 0.0 8.1e-20 70.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 EJP61382.1 - 0.071 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) DUF3667 PF12412.8 EJP61382.1 - 0.38 10.3 2.7 0.55 9.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) Zn_clus PF00172.18 EJP61383.1 - 0.24 11.5 1.6 0.61 10.3 1.6 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dimer_Tnp_hAT PF05699.14 EJP61384.1 - 9.6e-20 70.2 0.0 2.2e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DAO PF01266.24 EJP61385.1 - 3.7e-33 115.6 0.0 5.7e-33 114.9 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP61385.1 - 1.9e-08 33.9 0.0 0.0011 18.2 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP61385.1 - 1.4e-07 31.6 0.0 4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EJP61385.1 - 7.8e-07 28.5 0.1 0.01 15.0 0.4 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EJP61385.1 - 6.3e-05 22.2 4.9 0.0033 16.6 4.9 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EJP61385.1 - 9.3e-05 22.5 0.5 0.062 13.3 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EJP61385.1 - 0.00023 20.5 0.1 0.00039 19.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EJP61385.1 - 0.00047 19.1 0.5 0.0035 16.3 0.5 1.9 1 1 0 1 1 1 1 Tryptophan halogenase 3HCDH_N PF02737.18 EJP61385.1 - 0.00072 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EJP61385.1 - 0.0017 18.8 0.0 0.0075 16.8 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP61385.1 - 0.0022 16.8 0.4 0.016 14.0 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 EJP61385.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 EJP61385.1 - 0.017 14.3 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 EJP61385.1 - 0.019 15.4 0.0 0.037 14.5 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EJP61385.1 - 0.019 14.6 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 EJP61385.1 - 0.081 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF3759 PF12585.8 EJP61385.1 - 0.1 12.7 1.7 20 5.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3759) TrkA_N PF02254.18 EJP61385.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EJP61385.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EJP61385.1 - 0.15 11.1 0.2 0.98 8.4 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EJP61385.1 - 0.16 11.2 0.0 0.57 9.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EJP61385.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.7 EJP61385.1 - 0.17 11.2 1.3 0.33 10.3 1.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Dimer_Tnp_hAT PF05699.14 EJP61386.1 - 3.9e-22 77.8 0.2 9.3e-22 76.6 0.1 1.7 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Herpes_US9 PF06072.11 EJP61386.1 - 0.068 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF3723 PF12520.8 EJP61387.1 - 4e-59 200.7 0.0 5.8e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Response_reg PF00072.24 EJP61388.1 - 2.9e-26 91.8 0.2 4.4e-26 91.2 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EJP61388.1 - 6.8e-22 78.1 0.1 1.6e-21 76.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.6 EJP61389.1 - 0.0001 22.5 0.0 0.00027 21.1 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 EJP61389.1 - 0.0043 16.7 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M43 PF05572.13 EJP61389.1 - 0.0053 16.7 0.3 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EJP61389.1 - 0.0064 17.0 1.4 0.014 16.0 0.0 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EJP61389.1 - 0.0075 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EJP61389.1 - 0.04 13.8 0.3 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Trypan_PARP PF05887.11 EJP61389.1 - 2.6 8.0 17.1 5 7.1 17.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FapA PF03961.13 EJP61389.1 - 8.1 4.9 9.2 3 6.4 6.6 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Dimer_Tnp_hAT PF05699.14 EJP61390.1 - 1e-15 57.2 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region adh_short_C2 PF13561.6 EJP61391.1 - 1.6e-53 181.7 0.0 2e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP61391.1 - 3.2e-37 127.9 0.2 4.5e-37 127.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP61391.1 - 7.5e-11 42.3 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EJP61391.1 - 0.017 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EJP61391.1 - 0.023 14.1 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Acyl-CoA_dh_1 PF00441.24 EJP61392.1 - 3.7e-41 140.8 0.6 6.7e-41 140.0 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EJP61392.1 - 2.7e-33 115.0 0.1 5.6e-33 114.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EJP61392.1 - 3.8e-28 97.5 0.2 7e-28 96.7 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EJP61392.1 - 2.2e-13 50.7 0.1 9.4e-13 48.6 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EJP61392.1 - 2.1e-06 27.6 0.2 5.1e-06 26.3 0.2 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 EJP61393.1 - 8.1e-133 443.6 0.1 1e-132 443.3 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EJP61393.1 - 0.13 11.7 0.2 7.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) ELH PF02323.15 EJP61394.1 - 0.046 13.1 0.3 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Egg-laying hormone precursor EGF_2 PF07974.13 EJP61394.1 - 4.1 7.9 10.8 7.7 7.0 10.8 1.5 1 0 0 1 1 1 0 EGF-like domain Gmx_para_CXXCG PF09535.10 EJP61395.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) LANC_like PF05147.13 EJP61397.1 - 2.9e-15 55.7 0.0 5.1e-14 51.6 0.0 2.0 1 1 2 3 3 3 3 Lanthionine synthetase C-like protein Zn_clus PF00172.18 EJP61398.1 - 4e-08 33.3 11.5 7.2e-08 32.4 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_23 PF13476.6 EJP61398.1 - 0.0071 16.9 4.0 0.0098 16.4 4.0 1.3 1 0 0 1 1 1 1 AAA domain FHIPEP PF00771.20 EJP61398.1 - 0.031 12.8 1.8 0.047 12.2 1.8 1.2 1 0 0 1 1 1 0 FHIPEP family eIF-3_zeta PF05091.12 EJP61398.1 - 0.09 11.7 11.5 0.14 11.1 11.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 EJP61398.1 - 0.97 8.8 12.3 0.097 12.1 6.5 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) EMC3_TMCO1 PF01956.16 EJP61398.1 - 1.4 8.7 9.1 2.4 7.9 9.1 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MDM31_MDM32 PF08118.11 EJP61398.1 - 1.5 7.4 8.4 0.62 8.7 3.5 2.1 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF4175 PF13779.6 EJP61398.1 - 1.5 6.7 26.9 0.082 10.8 21.7 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Het-C PF07217.11 EJP61398.1 - 1.6 7.1 6.7 3.9 5.9 6.7 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C RICTOR_N PF14664.6 EJP61398.1 - 1.6 7.6 3.4 2.8 6.8 3.4 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term VIT1 PF01988.19 EJP61398.1 - 2.4 8.0 3.9 8 6.3 3.9 1.8 1 0 0 1 1 1 0 VIT family GREB1 PF15782.5 EJP61398.1 - 2.7 5.0 17.9 3.5 4.6 17.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Maf1 PF09174.10 EJP61398.1 - 2.9 8.0 8.1 0.44 10.7 3.2 2.1 2 0 0 2 2 2 0 Maf1 regulator Ndc1_Nup PF09531.10 EJP61398.1 - 3.4 6.2 21.1 5.8 5.5 21.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Folate_carrier PF01770.18 EJP61398.1 - 4.3 6.0 4.9 7.4 5.2 4.9 1.3 1 0 0 1 1 1 0 Reduced folate carrier CLN3 PF02487.17 EJP61398.1 - 4.5 6.2 11.1 0.076 12.1 3.9 1.6 2 0 0 2 2 2 0 CLN3 protein OATP PF03137.20 EJP61398.1 - 5.1 5.3 7.2 10 4.3 7.2 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF719 PF05334.13 EJP61398.1 - 6 7.0 14.7 3 8.0 10.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF2722 PF10846.8 EJP61398.1 - 6.6 5.6 36.6 0.29 10.0 29.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Orf78 PF06024.12 EJP61398.1 - 9.8 6.5 6.7 33 4.9 6.7 1.9 1 0 0 1 1 1 0 Orf78 (ac78) Spc24 PF08286.11 EJP61399.1 - 0.041 14.1 11.7 0.69 10.2 2.5 3.0 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.17 EJP61399.1 - 0.065 13.1 0.5 0.065 13.1 0.5 2.7 2 1 0 2 2 2 0 Prefoldin subunit Lge1 PF11488.8 EJP61399.1 - 0.066 13.4 1.0 0.066 13.4 1.0 3.3 3 1 1 4 4 4 0 Transcriptional regulatory protein LGE1 DHR10 PF18595.1 EJP61399.1 - 0.085 12.9 23.0 0.58 10.2 21.0 2.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain FliD_N PF02465.18 EJP61399.1 - 0.093 13.4 4.1 1.9 9.2 0.3 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4435 PF14491.6 EJP61399.1 - 0.12 12.3 2.8 0.69 9.8 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4435) BLOC1_2 PF10046.9 EJP61399.1 - 0.14 12.5 8.1 0.053 13.8 2.5 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 EJP61399.1 - 0.18 10.7 20.7 0.15 10.9 5.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 EJP61399.1 - 0.28 10.7 16.8 0.18 11.3 6.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein Laminin_II PF06009.12 EJP61399.1 - 0.6 10.1 9.6 1.9 8.5 1.1 2.4 1 1 0 2 2 2 0 Laminin Domain II OmpH PF03938.14 EJP61399.1 - 0.86 9.9 20.9 1.1 9.5 2.2 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fez1 PF06818.15 EJP61399.1 - 1.1 9.6 18.2 2.8 8.3 6.1 1.9 1 1 1 2 2 2 0 Fez1 Bacillus_HBL PF05791.11 EJP61399.1 - 1.5 8.6 5.1 6 6.7 0.4 2.6 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 EJP61399.1 - 1.8 8.6 15.3 3 7.9 1.0 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 EJP61399.1 - 2.2 6.1 4.0 3.2 5.5 4.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4047 PF13256.6 EJP61399.1 - 2.7 8.2 5.0 0.79 9.9 0.5 2.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4047) Csm1_N PF18504.1 EJP61399.1 - 2.8 8.4 16.4 11 6.5 2.2 3.6 3 0 0 3 3 3 0 Csm1 N-terminal domain LMBR1 PF04791.16 EJP61399.1 - 3.4 6.5 4.2 4 6.2 4.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_MLP1_2 PF07926.12 EJP61399.1 - 4.5 7.3 20.9 2.2 8.3 5.3 2.7 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FapA PF03961.13 EJP61399.1 - 4.6 5.7 10.9 31 3.0 11.0 1.9 1 1 0 1 1 1 0 Flagellar Assembly Protein A PEARLI-4 PF05278.12 EJP61399.1 - 5.7 6.4 13.5 1.4 8.4 3.0 2.3 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF3563 PF12086.8 EJP61399.1 - 5.9 6.7 6.5 2.8 7.8 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3563) zf-RING_2 PF13639.6 EJP61401.1 - 1.3e-12 47.8 5.1 2.1e-12 47.1 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJP61401.1 - 2.2e-09 37.0 3.9 3.5e-09 36.3 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 EJP61401.1 - 4e-09 36.4 0.0 9.7e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 EJP61401.1 - 6.4e-09 36.0 2.1 1.3e-08 35.0 2.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EJP61401.1 - 1.2e-08 34.7 3.1 1.9e-08 34.0 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJP61401.1 - 3.2e-08 33.2 2.2 3.2e-08 33.2 2.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EJP61401.1 - 5.7e-07 29.4 2.4 8.8e-07 28.8 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EJP61401.1 - 5.5e-06 26.3 1.8 5.2e-05 23.2 2.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EJP61401.1 - 9e-06 25.5 2.9 1.3e-05 24.9 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EJP61401.1 - 0.0012 18.8 0.9 0.0022 18.0 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EJP61401.1 - 0.006 16.4 2.6 0.01 15.7 2.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EJP61401.1 - 0.036 14.2 2.8 0.088 13.0 2.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EJP61401.1 - 0.052 13.2 2.9 0.1 12.2 2.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EJP61401.1 - 0.072 13.3 2.2 0.2 11.9 2.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EJP61401.1 - 0.23 11.6 2.8 0.49 10.6 2.8 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 EJP61401.1 - 0.93 9.4 2.5 1.8 8.5 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 EJP61401.1 - 1 9.3 2.4 1.8 8.5 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EJP61401.1 - 1.2 9.5 3.2 2 8.8 3.2 1.4 1 0 0 1 1 1 0 RING-like domain ERG4_ERG24 PF01222.17 EJP61404.1 - 2e-144 481.6 3.6 2.2e-144 481.4 3.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EJP61404.1 - 1.8e-05 24.4 0.1 4.7e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3630 PF12305.8 EJP61404.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) WD40 PF00400.32 EJP61406.1 - 2e-07 31.6 17.8 0.0013 19.5 0.4 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EJP61406.1 - 1.6e-06 27.6 10.1 3.6e-06 26.5 10.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 EJP61406.1 - 0.0041 17.4 0.0 0.0085 16.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain DZR PF12773.7 EJP61406.1 - 0.042 13.9 4.7 0.1 12.7 4.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Arabinose_Isome PF02610.15 EJP61406.1 - 0.25 10.5 0.1 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 L-arabinose isomerase Porphobil_deam PF01379.20 EJP61407.1 - 5.4e-71 238.3 0.0 7.4e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EJP61407.1 - 6.6e-18 64.9 0.4 1.2e-17 64.0 0.4 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain UQ_con PF00179.26 EJP61408.1 - 7.1e-48 161.8 0.0 8e-48 161.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP61408.1 - 0.0029 17.3 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EJP61408.1 - 0.0055 16.6 0.1 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 EJP61408.1 - 0.024 14.9 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Mt_ATP-synt_D PF05873.12 EJP61409.1 - 1.5e-20 73.6 3.3 1.8e-20 73.3 3.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T5orf172 PF10544.9 EJP61409.1 - 0.11 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 T5orf172 domain TPR_MLP1_2 PF07926.12 EJP61409.1 - 0.55 10.3 9.4 1.2 9.2 0.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 EJP61409.1 - 0.65 10.5 6.1 0.34 11.4 0.3 2.2 1 1 1 2 2 2 0 Spectrin repeat NAC PF01849.18 EJP61410.1 - 4.1e-24 84.3 0.2 1.5e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 NAC domain CENP-B_dimeris PF09026.10 EJP61410.1 - 0.04 14.3 9.7 1.7 9.1 6.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EJP61410.1 - 0.12 12.1 17.3 0.92 9.2 1.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.18 EJP61410.1 - 0.28 11.1 9.9 0.12 12.2 7.8 1.4 1 1 0 1 1 1 0 Myc amino-terminal region SpoIIIAH PF12685.7 EJP61410.1 - 0.97 9.2 12.9 0.28 11.0 8.2 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein PGA2 PF07543.12 EJP61410.1 - 4.1 7.4 13.9 10 6.1 7.1 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribosomal_L14e PF01929.17 EJP61411.1 - 1.8e-29 102.1 2.6 2.5e-29 101.6 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 Prot_ATP_ID_OB PF16450.5 EJP61411.1 - 0.0012 18.7 0.2 0.0025 17.8 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain KOW PF00467.29 EJP61411.1 - 0.0037 17.1 0.1 0.0037 17.1 0.1 1.8 2 0 0 2 2 2 1 KOW motif DUF1687 PF07955.11 EJP61412.1 - 5.1e-29 101.3 0.0 6.4e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) L51_S25_CI-B8 PF05047.16 EJP61414.1 - 7.3e-13 48.2 0.0 9.2e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.13 EJP61415.1 - 3.4e-47 159.1 0.3 3.4e-47 159.1 0.3 1.6 2 0 0 2 2 2 1 Mitochondrial pyruvate carriers TadE PF07811.12 EJP61415.1 - 0.064 13.5 2.3 0.18 12.1 1.5 2.1 2 0 0 2 2 2 0 TadE-like protein CNH PF00780.22 EJP61416.1 - 3.5e-59 200.7 0.0 6e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EJP61416.1 - 2.3e-36 125.7 1.6 3.5e-36 125.2 1.6 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EJP61416.1 - 3.8e-10 40.0 0.1 1.5e-09 38.0 0.0 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 EJP61416.1 - 0.017 15.0 0.2 8.6 6.2 0.0 2.4 2 0 0 2 2 2 0 PH domain PH PF00169.29 EJP61416.1 - 0.045 14.3 0.1 0.81 10.2 0.0 2.7 2 0 0 2 2 2 0 PH domain adh_short PF00106.25 EJP61417.1 - 1.9e-23 83.0 0.4 2.4e-23 82.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP61417.1 - 1.5e-17 64.0 0.2 1.9e-17 63.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EJP61417.1 - 0.0062 16.5 0.4 0.29 11.0 0.3 2.4 2 1 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EJP61417.1 - 0.021 14.8 1.2 0.03 14.2 0.1 1.8 2 0 0 2 2 2 0 KR domain GDP_Man_Dehyd PF16363.5 EJP61417.1 - 0.27 10.6 0.4 30 3.9 0.0 2.8 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase HgmA PF04209.13 EJP61418.1 - 1.6e-132 442.3 0.0 1.9e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase GED PF02212.18 EJP61420.1 - 0.028 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Dynamin GTPase effector domain SYCP2_ARLD PF18581.1 EJP61421.1 - 0.012 15.6 0.2 0.052 13.6 0.2 1.8 2 0 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain DRIM PF07539.12 EJP61421.1 - 0.018 13.4 0.0 0.023 13.0 0.0 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis Dynamin_M PF01031.20 EJP61421.1 - 0.031 13.5 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin central region Dynamin_N PF00350.23 EJP61422.1 - 4.1e-18 66.0 0.0 5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EJP61422.1 - 0.033 14.3 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_M PF01031.20 EJP61422.1 - 0.11 11.6 0.0 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 Dynamin central region Helo_like_N PF17111.5 EJP61423.1 - 6.3e-05 22.4 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Lectin_N PF03954.14 EJP61423.1 - 0.085 12.6 0.1 0.31 10.8 0.1 1.9 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain SET PF00856.28 EJP61426.1 - 9.6e-25 87.9 4.0 1.6e-11 44.9 0.2 3.9 2 2 0 2 2 2 2 SET domain Glyco_hydro_92 PF07971.12 EJP61426.1 - 0.11 11.4 0.1 4.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 92 AAA_12 PF13087.6 EJP61427.1 - 2.3e-28 99.2 0.0 4e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EJP61427.1 - 1.8e-12 47.6 0.2 1.8e-12 47.6 0.2 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EJP61427.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EJP61427.1 - 0.13 11.4 0.2 0.36 10.0 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) K-box PF01486.17 EJP61427.1 - 0.31 11.2 1.8 1.2 9.4 1.8 2.0 1 0 0 1 1 1 0 K-box region Dynamin_M PF01031.20 EJP61428.1 - 1.4e-33 116.3 0.1 5.5e-33 114.4 0.1 2.0 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EJP61428.1 - 1.2e-32 113.3 0.0 2.5e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EJP61428.1 - 0.00032 20.8 0.0 0.0014 18.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GerPC PF10737.9 EJP61428.1 - 0.21 11.6 3.4 4.9 7.2 0.1 3.6 3 1 1 4 4 4 0 Spore germination protein GerPC Trypan_PARP PF05887.11 EJP61429.1 - 2.4 8.2 12.7 3.5 7.6 8.1 2.4 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ribosomal_S27e PF01667.17 EJP61430.1 - 9.3 6.1 8.6 6 6.7 0.2 2.9 3 0 0 3 3 3 0 Ribosomal protein S27 Glyco_hydro_3 PF00933.21 EJP61431.1 - 5.1e-44 150.9 0.0 7.5e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EJP61431.1 - 1.5e-41 142.7 0.0 3e-41 141.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EJP61431.1 - 5.9e-24 84.0 0.2 1e-23 83.2 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 EJP61431.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 CARDB Dimer_Tnp_hAT PF05699.14 EJP61432.1 - 0.0002 21.1 0.0 0.00048 19.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HrpF PF06266.12 EJP61432.1 - 0.042 14.1 0.2 0.088 13.1 0.2 1.5 1 0 0 1 1 1 0 HrpF protein DUF4240 PF14024.6 EJP61433.1 - 0.18 12.0 0.3 0.35 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) DUF3295 PF11702.8 EJP61435.1 - 4.1e-107 359.6 19.5 9.5e-96 322.1 9.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EJP61435.1 - 8.2e-11 41.5 1.6 1.7e-10 40.6 1.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TFIIA PF03153.13 EJP61435.1 - 0.05 13.6 0.1 0.05 13.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit F-box PF00646.33 EJP61436.1 - 0.0022 17.8 0.0 0.0071 16.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain PspB PF06667.12 EJP61438.1 - 0.15 12.1 0.2 0.32 11.1 0.2 1.5 1 0 0 1 1 1 0 Phage shock protein B APH PF01636.23 EJP61442.1 - 8.1e-14 52.1 1.2 2.2e-13 50.7 0.0 2.3 3 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP61442.1 - 0.023 14.3 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EJP61442.1 - 0.087 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase UBA2_C PF16195.5 EJP61442.1 - 0.099 13.3 2.6 0.35 11.6 2.6 1.9 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus RVT_1 PF00078.27 EJP61443.1 - 1.6e-14 54.0 0.0 3.9e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_jaz PF12171.8 EJP61444.1 - 1.5e-08 34.7 0.1 2.9e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EJP61444.1 - 0.0022 18.3 0.3 0.0066 16.8 0.2 1.6 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-SCNM1 PF15803.5 EJP61444.1 - 0.036 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 zf-C2H2_4 PF13894.6 EJP61444.1 - 0.056 14.3 0.0 0.14 13.1 0.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-U1 PF06220.12 EJP61444.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger Aconitase PF00330.20 EJP61445.1 - 1.2e-148 496.0 0.0 1.5e-148 495.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EJP61445.1 - 2.2e-42 144.5 0.0 3.7e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Rhomboid PF01694.22 EJP61446.1 - 5e-13 49.3 10.0 5e-13 49.3 10.0 1.6 1 1 1 2 2 2 1 Rhomboid family DUF2070 PF09843.9 EJP61446.1 - 1.5 7.0 12.2 2 6.6 12.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Gaa1 PF04114.14 EJP61447.1 - 1.8e-163 545.2 9.5 2.1e-163 544.9 9.5 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.27 EJP61448.1 - 4.1e-08 33.7 0.0 9.1e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EJP61448.1 - 5.2e-06 26.0 1.3 1.3e-05 24.7 1.3 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix TPR_MalT PF17874.1 EJP61448.1 - 0.0045 16.4 0.6 0.0068 15.8 0.6 1.3 1 0 0 1 1 1 1 MalT-like TPR region Glyco_hydro_18 PF00704.28 EJP61449.1 - 5.6e-57 193.8 0.8 2e-56 192.0 0.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EJP61449.1 - 1.5e-11 44.5 16.9 1.5e-11 44.5 16.9 6.5 6 1 0 6 6 6 2 Chitin recognition protein LysM PF01476.20 EJP61450.1 - 4.2e-22 77.9 0.0 5.4e-06 26.4 0.1 4.4 4 0 0 4 4 4 4 LysM domain DIT1_PvcA PF05141.12 EJP61451.1 - 2.3e-102 342.2 0.0 2.8e-102 341.9 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ACBP PF00887.19 EJP61451.1 - 0.19 12.0 0.0 0.51 10.6 0.0 1.7 1 1 0 1 1 1 0 Acyl CoA binding protein p450 PF00067.22 EJP61452.1 - 1.3e-55 189.0 0.0 1.5e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATG22 PF11700.8 EJP61453.1 - 5.1e-131 437.6 16.7 5.7e-131 437.4 16.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like BP28CT PF08146.12 EJP61453.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 BP28CT (NUC211) domain MFS_1 PF07690.16 EJP61454.1 - 2e-42 145.4 45.8 1e-40 139.8 24.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP61454.1 - 4.7e-17 62.0 5.3 4.7e-17 62.0 5.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF5337 PF17272.2 EJP61454.1 - 2 8.3 6.6 3.7 7.4 0.0 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5337) Peptidase_A4 PF01828.17 EJP61455.1 - 2.8e-40 138.0 0.0 3.5e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family MFS_1 PF07690.16 EJP61456.1 - 5.6e-28 97.9 28.6 8.9e-28 97.2 28.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EJP61456.1 - 6.4e-08 32.3 5.8 6.4e-08 32.3 5.8 2.5 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB A_deaminase PF00962.22 EJP61457.1 - 1.1e-43 149.8 0.0 1.5e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase PAD PF03068.15 EJP61458.1 - 9.5e-127 423.2 0.0 1.2e-126 422.8 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Sdh_cyt PF01127.22 EJP61460.1 - 1.1e-12 48.1 2.3 1.5e-12 47.6 2.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit adh_short_C2 PF13561.6 EJP61461.1 - 1.7e-51 175.1 0.0 2.2e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP61461.1 - 1.2e-46 158.7 0.0 1.4e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP61461.1 - 6.4e-09 36.0 0.1 9.4e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP61461.1 - 0.0049 16.4 0.0 0.0061 16.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 EJP61461.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF1776 PF08643.10 EJP61461.1 - 0.044 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EJP61461.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FGGY_N PF00370.21 EJP61461.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain adh_short_C2 PF13561.6 EJP61462.1 - 1.6e-60 204.6 0.2 2e-60 204.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP61462.1 - 1.6e-47 161.5 0.6 2e-47 161.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP61462.1 - 1.4e-10 41.4 0.1 2e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EJP61462.1 - 0.0029 17.1 0.2 0.0047 16.4 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme THF_DHG_CYH_C PF02882.19 EJP61462.1 - 0.0095 15.3 0.4 0.028 13.8 0.1 1.9 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 EJP61462.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_N PF08240.12 EJP61463.1 - 4.5e-22 78.0 1.1 1e-21 76.9 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP61463.1 - 4.7e-08 33.1 0.1 7.7e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EJP61463.1 - 0.13 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF3435 PF11917.8 EJP61464.1 - 1.1e-61 209.1 0.0 9e-57 192.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) Phage_int_SAM_5 PF13102.6 EJP61464.1 - 0.00046 20.5 3.0 0.0017 18.6 3.0 2.0 1 0 0 1 1 1 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 EJP61464.1 - 0.62 10.6 7.2 2.7 8.5 7.2 2.2 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.25 EJP61465.1 - 3.1e-11 43.2 0.0 3.7e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EJP61465.1 - 1e-05 25.0 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EJP61465.1 - 8e-05 22.1 0.0 9.3e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP61465.1 - 0.00018 21.5 1.3 0.00066 19.7 0.4 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EJP61465.1 - 0.0013 18.3 0.1 0.0054 16.3 0.1 1.8 1 1 0 1 1 1 1 RIO1 family DUF4166 PF13761.6 EJP61466.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) DDE_3 PF13358.6 EJP61467.1 - 6.8e-21 74.6 0.0 9.7e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Synaptobrevin PF00957.21 EJP61468.1 - 2e-22 78.8 0.4 2.7e-22 78.3 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EJP61468.1 - 7.8e-11 41.9 0.0 5.2e-10 39.2 0.0 2.2 1 1 0 1 1 1 1 Regulated-SNARE-like domain IrmA PF18673.1 EJP61469.1 - 0.12 12.6 0.2 3.4 7.8 0.1 2.2 2 0 0 2 2 2 0 interleukin receptor mimic protein A Pkinase PF00069.25 EJP61471.1 - 0.0023 17.4 0.0 0.0056 16.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EJP61471.1 - 0.017 15.1 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family UCR_TM PF02921.14 EJP61471.1 - 0.21 12.1 0.1 0.21 12.1 0.1 2.3 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region DUF2956 PF11169.8 EJP61471.1 - 2.4 8.4 5.9 10 6.3 5.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) CbiK PF06180.11 EJP61479.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) RNase_H PF00075.24 EJP61480.1 - 6.1e-13 49.2 0.0 1.2e-12 48.2 0.0 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EJP61480.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase-like GATA PF00320.27 EJP61481.1 - 1e-13 50.7 3.6 1.7e-13 49.9 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger G_path_suppress PF15991.5 EJP61481.1 - 0.42 10.7 2.2 0.69 10.0 2.2 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor F-box-like PF12937.7 EJP61482.1 - 5e-05 23.1 0.2 0.00014 21.7 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP61482.1 - 0.00012 21.9 0.6 0.00012 21.9 0.6 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EJP61482.1 - 0.0027 17.6 0.5 0.0069 16.3 0.1 2.0 2 0 0 2 2 2 1 F-box A_deaminase PF00962.22 EJP61483.1 - 3.7e-17 62.6 0.0 4.2e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dimer_Tnp_hAT PF05699.14 EJP61484.1 - 3.7e-05 23.4 0.2 8.2e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Myb_DNA-bind_6 PF13921.6 EJP61488.1 - 0.0097 16.1 0.8 0.2 11.9 0.1 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EJP61488.1 - 0.031 14.5 0.1 0.089 13.0 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain UspA1_rep PF18792.1 EJP61492.1 - 0.13 12.8 0.6 0.32 11.6 0.6 1.7 1 0 0 1 1 1 0 Ubiquitous surface protein adhesin repeat Dimer_Tnp_hAT PF05699.14 EJP61493.1 - 2.1e-12 46.7 0.1 4.6e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region p450 PF00067.22 EJP61494.1 - 3.8e-48 164.4 0.0 6.2e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AHSA1 PF08327.11 EJP61497.1 - 0.0015 18.8 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Acyl-CoA_ox_N PF14749.6 EJP61497.1 - 0.061 13.9 0.3 0.1 13.1 0.3 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal FPN1 PF06963.12 EJP61498.1 - 0.074 11.6 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) zf-Di19 PF05605.12 EJP61498.1 - 0.085 13.2 0.5 0.43 10.9 0.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NUC173 PF08161.12 EJP61498.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NUC173 domain HNH_2 PF13391.6 EJP61499.1 - 2.5e-11 43.6 0.3 6.9e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease ORC6 PF05460.13 EJP61499.1 - 0.67 9.2 4.7 1.4 8.1 1.0 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) CrgA PF06781.12 EJP61500.1 - 0.57 10.3 6.2 0.089 12.9 2.3 1.6 2 0 0 2 2 2 0 Cell division protein CrgA Sdh_cyt PF01127.22 EJP61500.1 - 3.9 7.5 8.9 6.7 6.8 8.9 1.3 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-RVT PF13966.6 EJP61501.1 - 0.017 15.8 0.1 0.047 14.4 0.1 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase MFS_1 PF07690.16 EJP61502.1 - 1.2e-33 116.6 49.1 2.9e-32 112.0 45.3 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP61502.1 - 5e-09 35.5 6.4 5e-09 35.5 6.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP61502.1 - 7.7e-06 24.6 18.4 1.2e-05 24.0 18.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Asn_synthase PF00733.21 EJP61503.1 - 2.5e-63 214.9 0.0 3.8e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EJP61503.1 - 1.9e-30 105.3 0.0 3.1e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EJP61503.1 - 5.6e-27 94.6 0.0 9.9e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF4054 PF13262.6 EJP61503.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) NAD_synthase PF02540.17 EJP61503.1 - 0.26 10.4 0.1 0.41 9.7 0.1 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_bind PF01588.20 EJP61504.1 - 8.1e-16 57.9 0.2 7.6e-15 54.8 0.2 2.1 1 1 0 1 1 1 1 Putative tRNA binding domain N2227 PF07942.12 EJP61504.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein TPR_12 PF13424.6 EJP61506.1 - 6.7e-26 90.4 22.7 1.2e-08 35.1 1.1 6.6 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 EJP61506.1 - 1.4e-19 69.3 12.0 0.00091 19.0 0.0 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EJP61506.1 - 1.5e-09 37.9 21.1 0.59 11.1 0.0 8.4 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP61506.1 - 4.7e-09 36.1 12.8 4.7e-06 26.2 3.7 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 EJP61506.1 - 3e-08 33.2 18.5 0.29 11.4 0.1 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 EJP61506.1 - 2.6e-07 30.2 12.2 0.66 9.9 0.1 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat SBDS PF01172.18 EJP61506.1 - 3.1e-06 27.2 0.0 6.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein TPR_4 PF07721.14 EJP61506.1 - 5.1e-05 23.5 14.9 0.31 11.8 1.6 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP61506.1 - 6.7e-05 22.6 12.7 1.1 9.4 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP61506.1 - 8e-05 23.2 24.9 0.8 10.4 3.4 6.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EJP61506.1 - 0.003 18.0 17.6 0.74 10.4 0.3 5.2 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP61506.1 - 0.0046 17.1 2.9 59 4.3 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EJP61506.1 - 0.012 15.9 1.0 81 3.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EJP61506.1 - 0.039 13.6 1.2 11 5.9 0.1 4.1 4 0 0 4 4 4 0 TPR repeat TPR_21 PF09976.9 EJP61506.1 - 0.046 13.4 3.8 5.7 6.6 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain PhageMin_Tail PF10145.9 EJP61506.1 - 0.066 13.1 0.5 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Phage-related minor tail protein TPR_6 PF13174.6 EJP61506.1 - 5.6 7.8 14.5 1.8e+02 3.1 0.1 7.1 7 1 0 7 7 7 0 Tetratricopeptide repeat Tubulin PF00091.25 EJP61508.1 - 1.1e-68 231.4 0.0 1.7e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EJP61508.1 - 2e-41 141.1 0.0 3.6e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EJP61508.1 - 6.2e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EJP61508.1 - 0.02 14.1 0.0 0.083 12.1 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Tubulin_3 PF14881.6 EJP61508.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Dimer_Tnp_hAT PF05699.14 EJP61509.1 - 8.4e-15 54.3 0.1 1.9e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 EJP61509.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cyt-b5 PF00173.28 EJP61511.1 - 4e-07 30.1 0.6 1.1e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EJP61511.1 - 9.8e-07 28.9 7.3 1.6e-06 28.2 7.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Dimer_Tnp_hAT PF05699.14 EJP61512.1 - 4.4e-14 52.0 0.2 1.2e-13 50.6 0.2 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 EJP61512.1 - 0.16 12.0 3.4 0.27 11.3 1.8 2.2 2 0 0 2 2 2 0 BED zinc finger Cytochrom_C PF00034.21 EJP61512.1 - 0.21 12.7 3.5 3.9 8.7 1.1 3.2 2 0 0 2 2 2 0 Cytochrome c DZR PF12773.7 EJP61512.1 - 0.56 10.3 8.9 1.5 8.9 6.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon CEND1 PF15677.5 EJP61512.1 - 1.4 9.5 3.7 1.9 9.0 0.2 2.5 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 Zn_clus PF00172.18 EJP61513.1 - 2.3e-08 34.0 11.5 4.7e-08 33.0 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 EJP61513.1 - 1.4 9.3 6.4 0.25 11.7 1.6 2.0 2 0 0 2 2 2 0 Opy2 protein Methyltransf_33 PF10017.9 EJP61514.1 - 3.6e-78 262.9 0.0 4.3e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent CBM_21 PF03370.13 EJP61515.1 - 2.2e-18 66.5 0.0 3.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EJP61515.1 - 7.6e-11 42.4 0.0 1.4e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Abhydrolase_6 PF12697.7 EJP61516.1 - 0.0019 18.9 0.1 0.0042 17.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP61516.1 - 0.0054 16.4 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EJP61516.1 - 0.019 14.8 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 EJP61516.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3433 PF11915.8 EJP61519.1 - 0.0023 18.4 0.8 0.0065 16.9 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) zf-BED PF02892.15 EJP61522.1 - 0.00021 21.2 0.5 0.00043 20.2 0.5 1.6 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_12 PF18658.1 EJP61522.1 - 0.043 13.4 0.4 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger C2H2-type SAM_PNT PF02198.16 EJP61523.1 - 0.12 12.4 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain RVT_3 PF13456.6 EJP61524.1 - 2.8e-05 23.9 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 EJP61524.1 - 0.011 15.9 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 RNase H AraC_binding_2 PF14525.6 EJP61525.1 - 0.028 14.1 1.4 0.046 13.4 0.4 1.8 2 0 0 2 2 2 0 AraC-binding-like domain Sterol_MT_C PF08498.10 EJP61526.1 - 4.9e-13 49.2 0.2 8.4e-13 48.4 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Fungal_trans PF04082.18 EJP61527.1 - 0.0051 15.9 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3377 PF11857.8 EJP61528.1 - 0.033 14.1 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) MFS_5 PF05631.14 EJP61529.1 - 1.9e-20 73.1 0.6 2.2e-20 72.9 0.6 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EJP61529.1 - 5.8e-08 32.1 2.8 6.1e-08 32.0 2.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP61529.1 - 0.01 14.8 0.8 0.011 14.6 0.8 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1_like PF12832.7 EJP61529.1 - 0.038 12.8 0.0 0.046 12.6 0.0 1.0 1 0 0 1 1 1 0 MFS_1 like family Methyltransf_21 PF05050.12 EJP61530.1 - 6.2e-09 36.1 0.0 9.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Inhibitor_I9 PF05922.16 EJP61532.1 - 3.5e-08 34.0 0.1 1.7e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase inhibitor I9 TubC_N PF18563.1 EJP61532.1 - 0.002 18.1 0.0 0.0084 16.1 0.0 2.1 2 0 0 2 2 2 1 TubC N-terminal docking domain Peptidase_S8 PF00082.22 EJP61533.1 - 1.5e-29 103.2 4.2 1.8e-29 103.0 4.2 1.1 1 0 0 1 1 1 1 Subtilase family Asparaginase_C PF17763.1 EJP61533.1 - 0.09 13.0 0.8 0.21 11.8 0.4 1.8 1 1 1 2 2 2 0 Glutaminase/Asparaginase C-terminal domain Abhydrolase_3 PF07859.13 EJP61534.1 - 3e-31 108.9 0.0 2.8e-19 69.8 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold AAA_16 PF13191.6 EJP61535.1 - 1.5e-08 35.2 0.9 3.4e-08 34.1 0.3 1.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EJP61535.1 - 1.7e-07 31.3 0.0 3.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EJP61535.1 - 0.00073 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PNP_UDP_1 PF01048.20 EJP61535.1 - 0.0015 17.9 0.0 0.0033 16.7 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily PIF1 PF05970.14 EJP61535.1 - 0.0039 16.4 0.0 0.007 15.6 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 EJP61535.1 - 0.0065 16.5 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 EJP61535.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NB-ARC PF00931.22 EJP61535.1 - 0.12 11.6 0.0 0.37 10.0 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EJP61535.1 - 0.2 11.4 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C3HC4_2 PF13923.6 EJP61536.1 - 5.9e-09 35.6 5.6 5.9e-09 35.6 5.6 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP61536.1 - 8.6e-09 35.1 5.3 8.6e-09 35.1 5.3 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EJP61536.1 - 2.6e-08 33.9 6.7 2.6e-08 33.9 6.7 3.2 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EJP61536.1 - 1.3e-07 31.3 2.2 1.3e-07 31.3 2.2 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 EJP61536.1 - 2e-07 31.6 22.4 1.4e-06 28.8 2.7 3.5 1 1 1 3 3 3 2 TRAF-type zinc finger zf-RING_UBOX PF13445.6 EJP61536.1 - 2.2e-07 30.8 7.9 2.2e-07 30.8 7.9 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EJP61536.1 - 1.1e-06 28.9 5.8 1.1e-06 28.9 5.8 3.6 3 1 1 4 4 2 1 Ring finger domain zf-RING_5 PF14634.6 EJP61536.1 - 4.7e-06 26.4 3.0 4.7e-06 26.4 3.0 3.3 2 1 1 3 3 2 1 zinc-RING finger domain zf-Nse PF11789.8 EJP61536.1 - 0.0011 18.8 3.1 0.0011 18.8 3.1 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EJP61536.1 - 0.0063 16.8 1.8 0.0063 16.8 1.8 2.9 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EJP61536.1 - 0.026 14.6 1.1 0.026 14.6 1.1 2.2 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-TRAF_2 PF15965.5 EJP61536.1 - 1.2 9.6 26.3 0.24 11.9 14.1 3.1 1 1 2 3 3 3 0 TRAF-like zinc-finger zf-RING_6 PF14835.6 EJP61536.1 - 1.8 8.5 9.1 0.099 12.5 3.1 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Ufd2P_core PF10408.9 EJP61537.1 - 1.3e-195 651.7 9.5 1.5e-195 651.5 8.5 1.5 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 EJP61537.1 - 8.6e-25 86.7 2.0 4.9e-24 84.3 1.8 2.5 2 0 0 2 2 2 1 U-box domain GlutR_dimer PF00745.20 EJP61537.1 - 0.099 13.1 1.1 1.1 9.7 0.7 2.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain FAD_SOX PF18371.1 EJP61537.1 - 0.18 12.1 0.3 4.9 7.6 0.1 3.1 3 1 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Fungal_trans PF04082.18 EJP61538.1 - 1.9e-16 59.9 0.1 3.2e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP61538.1 - 4.4e-08 33.1 13.6 1.2e-07 31.7 13.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APC_N_CC PF16689.5 EJP61538.1 - 0.31 11.1 0.8 0.62 10.2 0.8 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain SPO22 PF08631.10 EJP61539.1 - 3.8e-06 26.6 2.4 6e-05 22.7 0.2 3.2 3 1 1 4 4 4 1 Meiosis protein SPO22/ZIP4 like ELYS PF13934.6 EJP61539.1 - 0.0089 16.0 0.5 0.0089 16.0 0.5 2.0 2 0 0 2 2 2 1 Nuclear pore complex assembly CobT PF06213.12 EJP61539.1 - 1.9 7.8 8.7 0.092 12.1 2.5 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT CAP PF00188.26 EJP61540.1 - 3.6e-22 79.5 4.7 7.5e-22 78.5 4.7 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ThiP_synth PF10120.9 EJP61540.1 - 0.18 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Thiamine-phosphate synthase SPO22 PF08631.10 EJP61541.1 - 2.1e-13 50.4 0.1 3.2e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like F-box PF00646.33 EJP61542.1 - 2.3e-05 24.1 4.4 2.9e-05 23.8 0.0 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EJP61542.1 - 3.8e-05 23.5 0.0 3.8e-05 23.5 0.0 2.9 4 0 0 4 4 4 1 F-box-like F-box_4 PF15966.5 EJP61542.1 - 0.00053 19.8 0.0 0.0016 18.3 0.0 1.7 1 1 0 1 1 1 1 F-box zf-C3HC4_3 PF13920.6 EJP61543.1 - 5 7.1 8.2 2.2 8.2 1.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.18 EJP61544.1 - 4.6e-06 26.6 8.1 8.2e-06 25.8 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Reovirus_M2 PF05993.12 EJP61544.1 - 0.016 13.3 0.2 0.077 11.1 0.0 1.8 1 1 1 2 2 2 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) SOG2 PF10428.9 EJP61544.1 - 5.6 6.0 10.3 9 5.4 10.3 1.4 1 1 0 1 1 1 0 RAM signalling pathway protein SKG6 PF08693.10 EJP61545.1 - 3.4e-06 26.4 1.7 7.6e-06 25.2 1.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ald_Xan_dh_C2 PF02738.18 EJP61546.1 - 3.8e-207 689.1 0.6 5.4e-207 688.6 0.6 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EJP61546.1 - 6.5e-48 162.7 0.0 1.3e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 EJP61546.1 - 9.5e-32 109.6 0.0 2.2e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 EJP61546.1 - 1.4e-30 105.5 0.1 5.8e-30 103.5 0.1 2.2 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 EJP61546.1 - 1.1e-29 102.3 0.1 2.6e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EJP61546.1 - 5.4e-07 29.5 2.0 7.4e-07 29.0 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF4213 PF13938.6 EJP61546.1 - 0.092 13.0 0.3 1.6 9.0 0.1 2.7 2 0 0 2 2 2 0 Putative heavy-metal chelation Sigma70_r3 PF04539.16 EJP61546.1 - 0.19 11.9 0.0 2.7 8.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-70 region 3 Aminotran_1_2 PF00155.21 EJP61547.1 - 9.8e-64 215.8 0.0 1.3e-63 215.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EJP61547.1 - 0.001 17.7 0.2 0.0023 16.5 0.2 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EJP61547.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EJP61547.1 - 0.0024 17.2 0.1 0.0048 16.3 0.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EJP61547.1 - 0.044 12.7 0.1 0.1 11.5 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V NmrA PF05368.13 EJP61548.1 - 4.8e-59 199.7 0.1 5.8e-59 199.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP61548.1 - 2.2e-16 60.3 0.0 3.6e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EJP61548.1 - 0.00021 20.4 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EJP61548.1 - 0.0012 19.1 0.1 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EJP61548.1 - 0.0099 15.4 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EJP61548.1 - 0.02 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain EFhand_Ca_insen PF08726.10 EJP61548.1 - 0.031 14.4 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand JmjC PF02373.22 EJP61549.1 - 1.5e-37 128.5 0.2 3.6e-37 127.3 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 EJP61549.1 - 4.8e-20 71.8 7.6 9e-20 70.9 7.6 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EJP61549.1 - 6.7e-19 67.9 7.6 6.7e-19 67.9 7.6 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 EJP61549.1 - 3e-14 52.7 0.8 9.5e-14 51.1 0.8 2.0 1 0 0 1 1 1 1 jmjN domain APH PF01636.23 EJP61551.1 - 9.8e-13 48.6 0.0 1.3e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP61551.1 - 1.6e-07 31.2 0.1 4.2e-07 29.8 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 EJP61551.1 - 2.8e-05 23.8 0.4 9.3e-05 22.1 0.2 1.8 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 EJP61551.1 - 5.5e-05 22.2 0.2 0.13 11.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.25 EJP61551.1 - 0.0081 15.6 0.0 0.078 12.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Fructosamin_kin PF03881.14 EJP61551.1 - 0.016 14.4 0.1 4.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.20 EJP61551.1 - 0.061 12.6 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 EJP61551.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family His_Phos_2 PF00328.22 EJP61552.1 - 7.6e-07 28.8 0.0 1.3e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Y_phosphatase3 PF13350.6 EJP61553.1 - 1.6e-46 159.2 0.0 1.8e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EJP61553.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EJP61553.1 - 0.013 15.0 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Nrap_D6 PF17407.2 EJP61553.1 - 0.099 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Nrap protein domain 6 Methyltransf_23 PF13489.6 EJP61554.1 - 2.2e-18 66.7 0.0 4.2e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP61554.1 - 1.2e-11 45.2 0.0 3.3e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP61554.1 - 1.1e-09 38.9 0.0 5.7e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP61554.1 - 2.4e-09 37.7 0.0 4.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP61554.1 - 7.2e-08 32.4 0.0 2.4e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EJP61554.1 - 0.00043 19.8 0.0 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 EJP61554.1 - 0.0043 16.4 0.0 0.0058 16.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EJP61554.1 - 0.037 13.4 0.0 0.16 11.3 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.18 EJP61554.1 - 0.049 13.1 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 EJP61554.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EJP61554.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FAD_binding_3 PF01494.19 EJP61555.1 - 8.4e-35 120.6 0.0 1.3e-34 120.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EJP61555.1 - 1.5e-09 37.6 0.1 0.0007 18.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EJP61555.1 - 1.9e-05 24.2 1.4 0.0079 15.5 0.1 3.4 3 1 1 4 4 4 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EJP61555.1 - 3.5e-05 23.0 1.2 0.11 11.6 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.27 EJP61555.1 - 5.3e-05 23.7 1.0 0.049 14.2 0.2 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP61555.1 - 0.0003 20.5 0.4 0.17 11.4 0.9 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP61555.1 - 0.00037 20.7 0.4 0.0013 18.9 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP61555.1 - 0.00058 19.2 0.4 0.044 13.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP61555.1 - 0.00085 18.1 1.0 0.58 8.8 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EJP61555.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 EJP61555.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ApbA PF02558.16 EJP61555.1 - 0.073 12.7 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 EJP61555.1 - 0.21 10.7 1.3 0.52 9.3 0.9 1.8 2 0 0 2 2 2 0 FAD binding domain PAD_porph PF04371.15 EJP61556.1 - 2e-79 267.2 0.0 2.5e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase WSC PF01822.19 EJP61558.1 - 9.6e-65 214.8 71.0 2.7e-18 66.0 10.7 5.5 5 0 0 5 5 5 4 WSC domain PQQ_3 PF13570.6 EJP61558.1 - 0.0091 16.5 0.2 0.0091 16.5 0.2 5.5 6 0 0 6 6 6 1 PQQ-like domain Prok-RING_1 PF14446.6 EJP61558.1 - 0.056 13.4 2.1 0.2 11.6 2.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ASH PF15780.5 EJP61558.1 - 1.2 9.3 11.6 1.7 8.9 0.0 3.6 4 1 0 4 4 4 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PQQ PF01011.21 EJP61558.1 - 7.2 6.7 6.1 30 4.8 0.6 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat NTP_transf_9 PF04248.12 EJP61560.1 - 4.3e-33 113.1 0.1 1.8e-25 88.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) BATS PF06968.13 EJP61561.1 - 9e-24 83.4 0.1 2.7e-23 81.9 0.1 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EJP61561.1 - 3.7e-15 56.7 0.1 7.4e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_1_2 PF00155.21 EJP61562.1 - 1.2e-33 116.8 0.0 7e-33 114.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EJP61563.1 - 1.7e-40 139.0 0.0 9e-23 80.6 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EJP61563.1 - 6.5e-18 65.3 0.0 1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain p450 PF00067.22 EJP61564.1 - 6.5e-89 298.8 0.0 7.9e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VSP PF03302.13 EJP61565.1 - 0.093 11.6 1.6 1.5 7.6 0.0 2.0 2 0 0 2 2 2 0 Giardia variant-specific surface protein DUF1485 PF07364.12 EJP61566.1 - 2.4e-109 365.1 0.1 3e-109 364.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 EJP61566.1 - 1.1e-57 195.1 0.1 1.6e-57 194.5 0.1 1.2 1 0 0 1 1 1 1 MlrC C-terminus Sugar_tr PF00083.24 EJP61567.1 - 4.1e-64 217.1 15.8 7.7e-49 166.8 1.7 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EJP61567.1 - 4.2e-21 75.2 25.7 4.2e-21 75.2 25.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EJP61567.1 - 2.3e-05 23.1 2.7 2.3e-05 23.1 2.7 3.2 3 1 0 4 4 4 1 MFS/sugar transport protein TRI12 PF06609.13 EJP61567.1 - 0.0024 16.4 2.3 0.0043 15.5 2.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EJP61567.1 - 0.021 13.7 3.2 0.45 9.3 2.0 2.2 2 0 0 2 2 2 0 MFS_1 like family Pro_racemase PF05544.11 EJP61568.1 - 4.8e-128 426.8 0.1 5.4e-128 426.6 0.1 1.0 1 0 0 1 1 1 1 Proline racemase Glyco_hydro_28 PF00295.17 EJP61569.1 - 1.7e-37 129.2 1.1 2.3e-37 128.8 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EJP61569.1 - 0.11 12.3 8.1 0.19 11.6 5.4 2.6 2 1 0 2 2 2 0 Right handed beta helix region DUF4159 PF13709.6 EJP61570.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Sugar_tr PF00083.24 EJP61571.1 - 3.9e-78 263.3 21.1 4.8e-78 263.0 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP61571.1 - 1.3e-15 57.2 56.2 1.1e-14 54.1 28.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 EJP61571.1 - 0.069 13.7 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Entericidin PF08085.11 EJP61571.1 - 0.11 12.5 0.4 0.28 11.3 0.4 1.8 1 0 0 1 1 1 0 Entericidin EcnA/B family PNK3P PF08645.11 EJP61572.1 - 1.7e-53 180.6 0.0 2.6e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EJP61572.1 - 2.2e-25 89.5 0.0 3.5e-22 79.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 EJP61572.1 - 0.0045 16.5 0.0 0.62 9.5 0.0 2.2 1 1 1 2 2 2 2 Chromatin associated protein KTI12 HAD PF12710.7 EJP61572.1 - 0.035 14.5 0.1 0.19 12.1 0.1 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase RsgA_GTPase PF03193.16 EJP61572.1 - 0.088 12.7 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EJP61572.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Med18 PF09637.10 EJP61573.1 - 1.4e-26 93.9 0.0 1.6e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 Med18 protein FRP PF18032.1 EJP61573.1 - 0.11 13.1 0.6 2 9.1 0.1 2.3 2 0 0 2 2 2 0 Photoprotection regulator fluorescence recovery protein APH PF01636.23 EJP61576.1 - 2.3e-06 27.7 4.0 1.3e-05 25.3 1.4 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP61576.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase WavE PF07507.11 EJP61577.1 - 0.024 13.8 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis Acetyltransf_8 PF13523.6 EJP61580.1 - 3.7e-37 127.2 0.0 6.8e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MCU PF04678.13 EJP61581.1 - 7.9e-24 84.7 0.1 7.9e-24 84.7 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial calcium uniporter MDD_C PF18376.1 EJP61583.1 - 1.4e-61 207.5 0.0 2.3e-61 206.8 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EJP61583.1 - 1.2e-07 31.8 3.1 1.4e-07 31.6 1.1 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF2388 PF09498.10 EJP61583.1 - 0.061 13.3 1.2 0.16 12.0 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2388) DUF647 PF04884.14 EJP61584.1 - 1.6e-93 312.8 3.0 1.6e-93 312.8 2.0 1.5 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis DUF4998 PF16389.5 EJP61584.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Cyto_heme_lyase PF01265.17 EJP61585.1 - 2.5e-43 148.8 10.8 4.5e-38 131.5 2.2 2.7 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase HCMVantigenic_N PF12154.8 EJP61585.1 - 0.21 11.7 0.9 0.52 10.5 0.9 1.6 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV Raptor_N PF14538.6 EJP61587.1 - 0.0018 18.2 0.0 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain zf-H2C2_5 PF13909.6 EJP61587.1 - 2 8.3 6.6 0.15 11.9 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 EJP61588.1 - 0.051 13.9 0.9 0.12 12.6 0.9 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EJP61588.1 - 7.5 7.2 12.1 22 5.7 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double domain TauE PF01925.19 EJP61591.1 - 0.31 10.6 13.5 0.95 9.0 7.8 2.2 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE DUF1435 PF07256.12 EJP61591.1 - 0.42 10.7 6.3 2.3 8.4 0.2 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1435) LapA_dom PF06305.11 EJP61591.1 - 3.1 7.7 11.8 0.8 9.6 0.1 3.8 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Fungal_trans_2 PF11951.8 EJP61593.1 - 1.9e-14 53.3 0.3 3.5e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EJP61593.1 - 3.6e-08 33.4 11.4 0.00019 21.7 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP61593.1 - 0.0053 17.5 9.4 0.29 12.1 0.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EJP61593.1 - 0.0079 16.6 9.7 0.19 12.2 1.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-trcl PF13451.6 EJP61593.1 - 0.011 15.7 0.7 0.04 13.8 0.7 2.0 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-C2H2_6 PF13912.6 EJP61593.1 - 0.16 12.0 2.6 0.14 12.2 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger ADK_lid PF05191.14 EJP61593.1 - 0.29 11.1 1.3 0.76 9.8 1.3 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 EJP61593.1 - 0.33 11.3 3.0 2.4 8.6 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 EJP61593.1 - 0.5 10.4 3.0 7.8 6.6 0.2 2.8 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2 PF00096.26 EJP61594.1 - 0.009 16.4 0.6 0.009 16.4 0.6 4.3 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 EJP61594.1 - 0.016 14.9 4.6 0.051 13.2 0.4 2.6 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 EJP61594.1 - 0.057 14.3 19.6 0.28 12.1 2.6 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP61594.1 - 2.7 8.4 0.0 2.7 8.4 0.0 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Methyltransf_25 PF13649.6 EJP61595.1 - 5.5e-12 46.2 0.0 1.6e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP61595.1 - 4.8e-10 40.0 0.0 1.1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP61595.1 - 4.1e-09 36.4 0.0 5.1e-08 32.8 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP61595.1 - 9.7e-09 35.3 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP61595.1 - 3.8e-05 24.3 0.0 0.00013 22.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EJP61595.1 - 4e-05 23.0 0.0 0.00012 21.5 0.0 1.5 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EJP61595.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 EJP61595.1 - 0.027 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EJP61595.1 - 0.03 13.9 0.0 0.079 12.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain zf-C2H2 PF00096.26 EJP61597.1 - 2.4e-08 34.0 9.8 0.00073 19.9 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP61597.1 - 0.00014 22.4 8.5 0.09 13.7 2.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger FANCL_C PF11793.8 EJP61597.1 - 0.085 13.1 0.6 0.24 11.6 0.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-H2C2_2 PF13465.6 EJP61597.1 - 1.6 9.3 9.9 2 9.0 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger double domain GATA PF00320.27 EJP61598.1 - 5.1e-12 45.2 2.2 9.5e-12 44.3 2.2 1.5 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 EJP61598.1 - 0.047 13.8 0.5 0.1 12.8 0.5 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 EJP61598.1 - 0.26 11.6 2.5 0.54 10.6 2.5 1.5 1 0 0 1 1 1 0 zinc-ribbon Rubredoxin_2 PF18073.1 EJP61598.1 - 0.46 10.3 5.0 8.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain GATase_6 PF13522.6 EJP61599.1 - 0.12 12.5 0.0 7.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Glutamine amidotransferase domain DUF4164 PF13747.6 EJP61599.1 - 0.15 12.3 3.0 0.74 10.1 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) HNH_2 PF13391.6 EJP61600.1 - 3.1e-10 40.0 0.2 9.6e-10 38.5 0.2 1.9 1 0 0 1 1 1 1 HNH endonuclease zf-met PF12874.7 EJP61602.1 - 4.4e-13 49.1 25.9 0.00021 21.6 2.4 6.6 7 1 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EJP61602.1 - 8.9e-11 41.7 26.4 0.041 14.7 0.0 7.2 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP61602.1 - 1.6e-10 41.0 30.0 0.00012 22.3 0.3 6.4 6 1 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EJP61602.1 - 1.4e-07 31.8 23.8 0.12 12.7 1.1 6.2 2 2 4 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EJP61602.1 - 1.3e-05 25.0 16.8 0.11 12.5 0.1 5.9 5 1 1 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP61602.1 - 0.00094 19.5 34.4 0.027 14.9 0.1 6.9 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP61602.1 - 0.0012 19.2 30.7 0.9 10.1 0.2 6.9 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 EJP61602.1 - 0.3 10.9 12.8 0.57 10.0 0.1 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type zf_ZIC PF18366.1 EJP61602.1 - 2.2 8.5 16.0 1.1 9.4 0.1 4.7 6 0 0 6 6 5 0 Zic proteins zinc finger domain zf-C2HE PF16278.5 EJP61602.1 - 3.1 8.3 16.2 16 6.0 3.8 4.8 4 1 1 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 EJP61602.1 - 3.1 7.5 17.6 3.2 7.4 0.1 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger AKAP95 PF04988.12 EJP61602.1 - 9.8 6.4 14.3 9.6 6.4 0.1 4.4 3 1 2 5 5 5 0 A-kinase anchoring protein 95 (AKAP95) Aminotran_3 PF00202.21 EJP61603.1 - 2.5e-78 263.6 0.0 2.9e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III RuBisCO_large PF00016.20 EJP61603.1 - 0.12 11.6 0.2 0.18 10.9 0.2 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Fig1 PF12351.8 EJP61604.1 - 0.00069 19.6 0.7 0.00069 19.6 0.7 2.1 3 0 0 3 3 3 1 Ca2+ regulator and membrane fusion protein Fig1 COX14 PF14880.6 EJP61604.1 - 0.0064 16.3 0.0 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 Cytochrome oxidase c assembly OTT_1508_deam PF14441.6 EJP61605.1 - 8.6e-19 67.3 0.4 2.1e-18 66.1 0.4 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase CTK3 PF12243.8 EJP61605.1 - 0.03 14.3 0.1 0.067 13.2 0.1 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 zf-3CxxC PF13695.6 EJP61606.1 - 6.4e-16 58.6 0.1 8.8e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding domain Chromo PF00385.24 EJP61607.1 - 0.06 13.3 10.9 0.22 11.5 0.8 3.2 3 1 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain Vac17 PF17321.2 EJP61607.1 - 0.068 12.6 0.0 0.097 12.1 0.0 1.1 1 0 0 1 1 1 0 Vacuole-related protein 17 HSP70 PF00012.20 EJP61608.1 - 6.8e-47 160.0 0.1 7.8e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJP61608.1 - 0.00076 18.4 1.0 0.038 12.8 0.5 3.0 2 1 0 2 2 2 1 MreB/Mbl protein SrfB PF07520.11 EJP61608.1 - 0.033 12.1 0.4 0.059 11.3 0.2 1.4 2 0 0 2 2 2 0 Virulence factor SrfB CENP-F_leu_zip PF10473.9 EJP61610.1 - 0.00098 19.2 9.0 0.0015 18.5 9.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 EJP61610.1 - 0.021 13.9 8.6 0.023 13.8 8.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EJP61610.1 - 0.04 14.0 4.1 0.065 13.3 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Helo_like_N PF17111.5 EJP61610.1 - 0.055 12.8 5.7 0.031 13.6 1.9 2.0 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins TMPIT PF07851.13 EJP61610.1 - 0.057 12.7 6.2 0.072 12.3 6.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 EJP61610.1 - 0.11 12.9 1.4 0.11 12.9 1.4 2.7 2 1 0 2 2 2 0 Cell division protein ZapB LNP1 PF15419.6 EJP61610.1 - 0.16 12.2 10.5 0.17 12.1 4.6 2.1 1 1 1 2 2 2 0 Leukemia NUP98 fusion partner 1 ACP_PD PF04336.12 EJP61610.1 - 0.25 11.8 7.3 1.3 9.5 1.7 2.2 1 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase PRKG1_interact PF15898.5 EJP61610.1 - 0.72 10.8 16.2 0.11 13.4 8.3 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain USP8_interact PF08941.10 EJP61610.1 - 0.75 9.6 9.4 0.97 9.2 7.8 1.8 1 1 1 2 2 2 0 USP8 interacting TRAF_BIRC3_bd PF16673.5 EJP61610.1 - 3.6 7.4 9.4 0.36 10.6 1.2 2.7 1 1 2 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Exonuc_VII_L PF02601.15 EJP61610.1 - 9.7 5.7 12.1 12 5.4 12.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 EJP61611.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF3192 PF11399.8 EJP61612.1 - 0.058 13.3 0.3 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Retrotrans_gag PF03732.17 EJP61615.1 - 2.6e-07 30.8 0.3 1.3e-06 28.6 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein SWC7 PF17330.2 EJP61615.1 - 0.096 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Methyltransf_7 PF03492.15 EJP61617.1 - 2.2e-33 115.9 0.0 2.9e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_25 PF13649.6 EJP61618.1 - 4.2e-16 59.4 0.0 8.3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP61618.1 - 9e-12 45.5 0.0 1.8e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP61618.1 - 3.6e-11 43.1 0.0 6.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP61618.1 - 7.1e-10 39.5 0.0 1.5e-09 38.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP61618.1 - 2.2e-09 37.0 0.0 3.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EJP61618.1 - 3.7e-07 30.1 0.0 5.1e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP61618.1 - 0.00014 21.4 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EJP61618.1 - 0.00025 20.1 0.0 0.00037 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 EJP61618.1 - 0.00039 20.6 0.0 0.00075 19.7 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EJP61618.1 - 0.00066 19.2 0.0 0.00091 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.16 EJP61618.1 - 0.00083 18.6 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme PCMT PF01135.19 EJP61618.1 - 0.0033 17.2 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EJP61618.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EJP61618.1 - 0.023 14.3 0.0 0.046 13.3 0.0 1.5 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 EJP61618.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EJP61618.1 - 0.24 10.3 0.0 0.35 9.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EJP61619.1 - 4.6e-08 33.7 0.0 8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP61619.1 - 1.7e-07 31.8 0.0 8.4e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP61619.1 - 2e-07 30.9 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP61619.1 - 5.7e-06 27.0 0.0 1e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP61619.1 - 3.5e-05 23.7 0.0 5.7e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MCH PF02289.16 EJP61619.1 - 0.018 14.4 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Cyclohydrolase (MCH) PrmA PF06325.13 EJP61619.1 - 0.14 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.11 EJP61619.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RVT_1 PF00078.27 EJP61622.1 - 1.7e-27 96.4 0.0 2.6e-25 89.2 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EJP61622.1 - 5e-12 45.7 0.7 1.4e-11 44.2 0.1 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase eIF2A PF08662.11 EJP61623.1 - 0.052 13.4 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Peptidase_M43 PF05572.13 EJP61624.1 - 1.1e-10 41.6 0.0 2.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EJP61624.1 - 0.0018 18.4 0.0 0.0036 17.5 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EJP61624.1 - 0.0032 17.1 0.3 0.0077 15.9 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EJP61624.1 - 0.0054 16.6 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 EJP61624.1 - 0.012 16.1 0.2 0.06 13.9 0.0 2.3 3 1 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Dimer_Tnp_hAT PF05699.14 EJP61627.1 - 5.1e-09 35.8 0.1 7.4e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3079 PF11278.8 EJP61627.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) Chromo PF00385.24 EJP61628.1 - 4e-06 26.6 1.0 4e-06 26.6 1.0 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3425 PF11905.8 EJP61631.1 - 5.1e-14 52.3 0.1 1e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Fmp27_WPPW PF10359.9 EJP61631.1 - 0.033 13.0 1.6 0.047 12.6 1.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ceramidase PF05875.12 EJP61633.1 - 3.7e-81 272.4 7.8 4.5e-81 272.2 7.8 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 EJP61633.1 - 0.011 15.6 1.6 0.04 13.8 1.6 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide Peptidase_U4 PF03419.13 EJP61633.1 - 0.074 12.3 9.8 0.018 14.3 4.3 1.9 1 1 1 2 2 2 0 Sporulation factor SpoIIGA ABC_cobalt PF09819.9 EJP61633.1 - 4.4 7.5 7.7 13 5.9 0.4 2.4 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component Glyco_hydro_18 PF00704.28 EJP61634.1 - 1.9e-37 129.7 0.2 2.8e-37 129.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RIP PF00161.19 EJP61635.1 - 1.1e-48 165.4 0.0 2.2e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Ribosome inactivating protein UNC-50 PF05216.13 EJP61636.1 - 0.036 13.6 0.6 0.036 13.6 0.6 1.9 2 0 0 2 2 2 0 UNC-50 family Peptidase_U4 PF03419.13 EJP61636.1 - 0.33 10.2 2.9 0.17 11.2 0.2 1.8 2 1 0 2 2 2 0 Sporulation factor SpoIIGA Ribonucleas_3_3 PF14622.6 EJP61637.1 - 2e-25 89.4 0.0 3.8e-25 88.5 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EJP61637.1 - 0.048 14.3 0.0 0.13 12.9 0.0 1.8 1 1 0 1 1 1 0 Ribonuclease III domain HAT_KAT11 PF08214.11 EJP61638.1 - 1.4e-90 304.1 0.0 1.8e-90 303.8 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein DUF601 PF04642.12 EJP61638.1 - 0.24 10.8 3.0 0.39 10.2 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Sugar_tr PF00083.24 EJP61639.1 - 2.6e-28 99.1 33.8 6.7e-17 61.5 12.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EJP61639.1 - 2.3e-19 69.5 41.7 1.3e-10 40.8 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 EJP61639.1 - 0.17 12.2 0.2 0.17 12.2 0.2 4.3 4 0 0 4 4 4 0 Transglycosylase associated protein Fungal_trans PF04082.18 EJP61640.1 - 1.1e-05 24.6 1.5 2.6e-05 23.4 1.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Involucrin2 PF06994.11 EJP61640.1 - 0.043 13.9 1.0 0.14 12.2 1.0 1.9 1 0 0 1 1 1 0 Involucrin CorA PF01544.18 EJP61641.1 - 2.8e-30 105.6 3.6 2.2e-27 96.2 1.4 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein POC1 PF10450.9 EJP61641.1 - 0.06 12.3 0.2 0.1 11.6 0.2 1.3 1 0 0 1 1 1 0 POC1 chaperone SPX PF03105.19 EJP61641.1 - 0.44 10.4 2.1 0.7 9.8 2.1 1.2 1 0 0 1 1 1 0 SPX domain UPRTase PF14681.6 EJP61642.1 - 8.4e-71 237.7 0.0 9.5e-71 237.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EJP61642.1 - 7.8e-06 25.5 0.0 1.8e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 EJP61642.1 - 0.0031 16.9 0.2 0.62 9.4 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase Pribosyl_synth PF14572.6 EJP61642.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Peptidase_M30 PF10460.9 EJP61642.1 - 0.081 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase M30 DNA_ligase_A_M PF01068.21 EJP61643.1 - 5.6e-42 143.7 0.0 9.3e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EJP61643.1 - 6.7e-41 140.5 0.0 1.1e-40 139.7 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 EJP61643.1 - 5.3e-20 71.6 0.0 7.4e-10 39.1 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 EJP61643.1 - 1.4e-17 64.5 0.0 4.9e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 RNA ligase DNA_ligase_A_C PF04679.15 EJP61643.1 - 4.9e-14 52.7 0.0 3.8e-13 49.9 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 EJP61643.1 - 2.1e-08 34.4 0.0 2.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EJP61643.1 - 2e-05 24.8 0.0 0.035 14.4 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EJP61643.1 - 0.0088 15.9 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain DNA_ligase_IV PF11411.8 EJP61643.1 - 0.0097 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.7 EJP61643.1 - 0.016 15.2 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 twin BRCT domain mRNA_cap_enzyme PF01331.19 EJP61643.1 - 0.1 12.4 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Methyltransf_11 PF08241.12 EJP61644.1 - 9e-10 39.1 0.0 2.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP61644.1 - 1.3e-09 38.6 0.0 2.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP61644.1 - 6.2e-09 36.5 0.0 1.3e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP61644.1 - 1.5e-06 28.2 0.0 2.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF2313 PF10076.9 EJP61644.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) CRCB PF02537.15 EJP61645.1 - 3.8e-39 132.9 15.7 4.1e-23 81.5 8.1 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) UPF0506 PF11703.8 EJP61646.1 - 3e-08 33.9 43.7 0.00058 20.2 15.1 3.4 1 1 2 3 3 3 3 UPF0506 Dickkopf_N PF04706.12 EJP61646.1 - 9.6e-06 26.0 44.0 0.064 13.8 3.7 4.1 1 1 3 4 4 4 4 Dickkopf N-terminal cysteine-rich region Conotoxin PF02950.17 EJP61646.1 - 1.2e-05 26.2 48.6 0.0065 17.5 5.1 4.1 1 1 3 4 4 4 3 Conotoxin Conotoxin_I2 PF17557.2 EJP61646.1 - 0.00043 20.3 53.8 0.67 10.1 7.3 4.4 4 0 0 4 4 4 4 I2-superfamily conotoxins Toxin_7 PF05980.12 EJP61646.1 - 0.017 15.3 53.3 0.48 10.7 7.8 4.6 4 0 0 4 4 4 0 Toxin 7 FA_desaturase PF00487.24 EJP61647.1 - 6.3e-19 68.8 14.0 6.3e-19 68.8 14.0 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EJP61647.1 - 8.6e-18 64.3 0.0 2.3e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Oleosin PF01277.17 EJP61647.1 - 0.15 11.8 0.8 0.39 10.5 0.8 1.6 1 0 0 1 1 1 0 Oleosin WD40 PF00400.32 EJP61648.1 - 1.9e-09 38.0 0.9 0.0016 19.2 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP61648.1 - 0.023 15.0 0.0 11 6.4 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EJP61648.1 - 0.082 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split SelP_N PF04592.14 EJP61648.1 - 0.11 11.8 5.5 0.23 10.8 5.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ge1_WD40 PF16529.5 EJP61648.1 - 0.14 11.1 0.2 5 6.0 0.1 2.4 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sua5_yciO_yrdC PF01300.18 EJP61651.1 - 3.4e-12 46.2 0.0 4.2e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination MFS_1 PF07690.16 EJP61652.1 - 7.3e-33 113.9 30.9 7.3e-33 113.9 30.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EJP61652.1 - 0.00051 18.5 2.4 0.00071 18.0 0.7 2.1 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Cyclin_N PF00134.23 EJP61653.1 - 0.015 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Cyclin, N-terminal domain TFIIB PF00382.19 EJP61653.1 - 0.071 13.2 0.0 4.1 7.5 0.0 2.5 2 1 0 2 2 2 0 Transcription factor TFIIB repeat Ank_2 PF12796.7 EJP61654.1 - 9.3e-30 103.1 0.0 6.6e-10 39.4 0.0 7.7 3 2 3 7 7 7 4 Ankyrin repeats (3 copies) NACHT_N PF17100.5 EJP61654.1 - 1.2e-23 84.2 0.5 3.6e-23 82.6 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Ank_4 PF13637.6 EJP61654.1 - 4.5e-22 78.1 0.5 4.2e-06 27.2 0.0 7.0 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP61654.1 - 4.1e-19 66.7 0.8 0.001 19.4 0.0 9.4 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 EJP61654.1 - 6.8e-18 64.3 1.2 0.00072 19.9 0.0 6.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EJP61654.1 - 4.2e-16 58.8 0.5 4.6e-07 30.0 0.0 5.4 4 2 2 6 6 6 4 Ankyrin repeats (many copies) DNA_pol_P_Exo PF18049.1 EJP61654.1 - 0.011 15.1 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo AAA_16 PF13191.6 EJP61654.1 - 0.034 14.5 0.0 0.18 12.2 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_S10 PF00450.22 EJP61655.1 - 6.4e-81 272.9 0.3 8.6e-81 272.5 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_M3 PF01432.20 EJP61656.1 - 1.2e-88 298.5 0.0 1.7e-88 297.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Importin_rep_4 PF18808.1 EJP61657.1 - 1.5e-33 114.9 0.7 1.5e-33 114.9 0.7 5.4 4 1 2 6 6 6 1 Importin repeat Importin_rep_5 PF18816.1 EJP61657.1 - 4.1e-21 75.0 0.8 8.5e-20 70.8 0.5 2.9 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 EJP61657.1 - 2.4e-20 72.6 5.4 2.2e-09 37.6 0.2 7.8 9 1 0 9 9 7 3 HEAT-like repeat HEAT PF02985.22 EJP61657.1 - 3.8e-13 48.5 13.4 0.0097 16.1 0.0 11.3 13 0 0 13 13 10 2 HEAT repeat Importin_rep_6 PF18829.1 EJP61657.1 - 2e-12 47.2 0.5 2e-12 47.2 0.5 3.9 4 0 0 4 4 4 1 Importin repeat 6 HEAT_2 PF13646.6 EJP61657.1 - 4.2e-12 46.3 11.6 0.00012 22.4 0.0 7.6 4 3 5 9 9 9 4 HEAT repeats RIX1 PF08167.12 EJP61657.1 - 1.6e-10 41.1 0.1 5.6e-05 23.0 0.0 5.0 4 1 0 5 5 5 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 EJP61657.1 - 1.6e-06 27.5 5.1 0.00037 19.7 0.1 3.8 3 2 1 4 4 4 1 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EJP61657.1 - 2.3e-06 28.1 2.4 0.8 10.3 0.0 6.8 4 2 4 8 8 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EJP61657.1 - 1.7e-05 24.9 3.9 10 6.1 0.1 6.0 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 EJP61657.1 - 0.00014 21.8 0.8 0.7 9.8 0.1 5.4 6 1 2 8 8 7 1 Domain of unknown function (DUF3385) UNC45-central PF11701.8 EJP61657.1 - 0.00019 21.4 4.2 1.2 9.1 0.3 4.5 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 EJP61657.1 - 0.0011 18.6 4.8 0.14 11.7 0.1 4.6 4 2 0 4 4 4 1 CLASP N terminal Telomere_reg-2 PF10193.9 EJP61657.1 - 0.0019 18.6 7.8 0.019 15.4 0.7 4.1 4 0 0 4 4 4 1 Telomere length regulation protein IBN_N PF03810.19 EJP61657.1 - 0.0019 18.1 3.4 0.057 13.3 0.1 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.14 EJP61657.1 - 0.0019 17.5 1.8 0.89 8.8 0.0 3.1 2 1 0 2 2 2 2 V-ATPase subunit H CAS_CSE1 PF03378.15 EJP61657.1 - 0.003 16.1 6.6 1.9 6.9 0.1 4.8 3 2 1 5 5 5 1 CAS/CSE protein, C-terminus RTP1_C1 PF10363.9 EJP61657.1 - 0.019 15.1 2.7 0.46 10.7 0.2 4.1 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 EJP61657.1 - 0.023 14.4 0.3 14 5.3 0.0 4.3 5 0 0 5 5 4 0 Domain of unknown function (DUF4042) DUF5624 PF18538.1 EJP61657.1 - 0.029 14.5 1.1 18 5.5 0.0 4.1 4 0 0 4 4 3 0 Domain of unknown function (DUF5624) DNA_alkylation PF08713.11 EJP61657.1 - 0.046 13.4 1.2 0.19 11.5 0.1 2.6 3 0 0 3 3 3 0 DNA alkylation repair enzyme DUF3361 PF11841.8 EJP61657.1 - 0.054 13.4 2.9 2.2 8.2 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Cytokin_check_N PF10407.9 EJP61657.1 - 0.11 12.5 0.4 17 5.5 0.1 2.6 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Cnd3 PF12719.7 EJP61657.1 - 0.18 10.9 2.6 1.3 8.2 0.0 3.2 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain FANCI_S3 PF14677.6 EJP61657.1 - 1 9.0 3.7 2.1 8.0 0.1 2.8 3 0 0 3 3 3 0 FANCI solenoid 3 CLN3 PF02487.17 EJP61659.1 - 1.8e-158 527.8 4.4 2.1e-158 527.6 4.4 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EJP61659.1 - 8.2e-05 21.7 26.6 0.0024 16.8 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 EJP61660.1 - 3.1e-07 30.4 11.3 5.8e-07 29.5 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP61660.1 - 1.4e-06 27.4 0.5 2.1e-06 26.8 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNCAIP_SNCA_bd PF16700.5 EJP61660.1 - 0.13 12.0 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Nucleotid_trans PF03407.16 EJP61661.1 - 0.00048 20.2 0.1 0.0011 19.1 0.1 1.5 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 EJP61661.1 - 0.0058 16.4 0.4 0.011 15.4 0.4 1.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MFS_1 PF07690.16 EJP61662.1 - 5e-31 107.9 40.3 5e-31 107.9 40.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyrophosphatase PF00719.19 EJP61663.1 - 3.2e-32 111.6 0.0 9.5e-31 106.8 0.0 2.2 1 1 0 1 1 1 1 Inorganic pyrophosphatase DinB_2 PF12867.7 EJP61663.1 - 0.18 12.3 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 DinB superfamily PHO4 PF01384.20 EJP61664.1 - 1.3e-112 376.2 14.1 1.6e-112 375.9 14.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF1674 PF07896.12 EJP61665.1 - 8.4e-15 55.0 7.9 8.4e-15 55.0 7.9 2.2 2 2 0 2 2 2 1 Protein of unknown function (DUF1674) DUF1615 PF07759.12 EJP61665.1 - 0.083 12.1 0.2 0.097 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Rxt3 PF08642.10 EJP61666.1 - 5.4e-41 140.3 0.0 2.5e-40 138.2 0.0 2.2 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EJP61666.1 - 0.00031 20.8 0.0 0.0041 17.2 0.0 2.3 1 1 0 1 1 1 1 LCCL domain Abhydrolase_6 PF12697.7 EJP61667.1 - 0.00091 19.9 7.9 0.0023 18.6 7.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Mitofilin PF09731.9 EJP61667.1 - 0.12 11.2 12.2 0.15 10.8 12.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF842 PF05811.13 EJP61667.1 - 0.37 10.5 2.7 0.87 9.3 2.7 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Mod_r PF07200.13 EJP61667.1 - 4 7.5 6.5 7.5 6.6 1.7 2.2 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ferritin PF00210.24 EJP61667.1 - 6.9 6.6 8.3 4.2 7.3 2.0 2.6 1 1 2 3 3 3 0 Ferritin-like domain PSK_trans_fac PF07704.11 EJP61667.1 - 8.4 7.2 7.8 4.2 8.2 1.9 2.9 1 1 2 3 3 3 0 Rv0623-like transcription factor NADH_dh_m_C1 PF15088.6 EJP61668.1 - 0.38 10.4 0.1 0.38 10.4 0.1 2.1 3 0 0 3 3 3 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Glyco_hydro_76 PF03663.14 EJP61669.1 - 9e-48 163.6 7.1 9e-48 163.6 7.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EJP61669.1 - 1.6e-08 34.0 7.9 0.00012 21.3 0.0 3.4 2 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 EJP61669.1 - 0.00083 18.9 0.2 1.4 8.4 0.0 2.5 2 1 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 EJP61669.1 - 0.0047 15.5 0.1 0.16 10.4 0.0 2.2 1 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 K_channel_TID PF07941.11 EJP61669.1 - 1.3 9.5 8.1 2.9 8.4 0.1 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Zn_clus PF00172.18 EJP61670.1 - 2.3e-05 24.4 11.2 4.1e-05 23.6 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sod_Fe_C PF02777.18 EJP61672.1 - 6.7e-38 129.0 0.1 1.4e-37 127.9 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EJP61672.1 - 5.6e-30 103.6 1.3 9.2e-30 103.0 1.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pkinase PF00069.25 EJP61673.1 - 3.6e-68 229.8 0.0 4.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61673.1 - 1.9e-39 135.5 0.0 2.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP61673.1 - 1.5e-08 34.4 0.0 7e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EJP61673.1 - 1.7e-05 24.3 0.1 2.7e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP61673.1 - 0.085 12.8 0.9 0.33 10.8 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1338 PF07063.13 EJP61674.1 - 4.4e-107 358.0 0.0 5.2e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) HrpF PF06266.12 EJP61674.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 HrpF protein Sld5 PF05916.11 EJP61675.1 - 4.6e-16 59.2 0.0 8.6e-16 58.4 0.0 1.4 2 0 0 2 2 2 1 GINS complex protein Tir_receptor_C PF07489.11 EJP61676.1 - 0.25 11.3 11.4 0.66 9.9 1.5 2.7 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) C-terminus Atrophin-1 PF03154.15 EJP61676.1 - 1.7 6.8 5.6 3.1 6.0 5.6 1.4 1 0 0 1 1 1 0 Atrophin-1 family zf-C2H2_jaz PF12171.8 EJP61677.1 - 1.2 9.5 4.6 1 9.7 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EJP61677.1 - 2.2 9.3 5.1 0.92 10.5 1.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Meth_synt_2 PF01717.18 EJP61678.1 - 6.9e-152 505.3 0.0 4.5e-147 489.5 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EJP61678.1 - 5.6e-118 394.0 0.1 6.6e-110 367.5 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EJP61678.1 - 3e-05 23.4 0.0 0.045 12.9 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 EJP61678.1 - 0.029 14.1 0.4 0.093 12.5 0.4 1.9 1 0 0 1 1 1 0 Short C-terminal domain VbhA PF18495.1 EJP61678.1 - 0.081 12.8 0.0 3.5 7.6 0.0 2.9 2 0 0 2 2 2 0 Antitoxin VbhA Put_DNA-bind_N PF06971.13 EJP61678.1 - 0.081 13.0 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus AT_hook PF02178.19 EJP61679.1 - 0.021 14.6 13.3 0.64 10.1 2.2 3.2 2 0 0 2 2 2 0 AT hook motif TRAUB PF08164.12 EJP61679.1 - 1.6 9.3 7.6 0.15 12.6 2.0 2.1 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal Thr_synth_N PF14821.6 EJP61680.1 - 1.5e-27 95.6 0.0 4.9e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EJP61680.1 - 1.7e-18 67.1 0.1 5.8e-17 62.0 0.1 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mito_carr PF00153.27 EJP61681.1 - 6.1e-21 74.1 1.0 1.7e-10 40.6 0.3 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Sulfatase PF00884.23 EJP61682.1 - 9.2e-77 258.5 0.0 1.1e-76 258.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EJP61682.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF229 PF02995.17 EJP61682.1 - 0.068 11.8 0.1 0.15 10.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF229) DUF4994 PF16385.5 EJP61682.1 - 0.17 11.8 0.0 0.44 10.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function Sugar_tr PF00083.24 EJP61683.1 - 5.5e-87 292.5 15.7 6.2e-87 292.3 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP61683.1 - 7.2e-20 71.2 12.5 7.2e-20 71.2 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DFRP_C PF16543.5 EJP61684.1 - 1.2e-24 86.6 5.2 1.2e-24 86.6 5.2 4.2 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EJP61684.1 - 2.6e-06 27.2 0.3 2.6e-06 27.2 0.3 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EJP61684.1 - 5.7e-05 23.8 3.4 5.7e-05 23.8 3.4 3.8 2 2 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 EJP61684.1 - 9.4e-05 22.1 6.2 0.0038 17.0 1.1 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EJP61684.1 - 0.00015 21.7 5.3 0.00015 21.7 5.3 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 EJP61684.1 - 0.0012 19.0 1.8 0.037 14.2 0.7 2.7 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EJP61684.1 - 0.017 15.6 13.0 0.079 13.5 3.8 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger NT-C2 PF10358.9 EJP61684.1 - 0.052 13.3 3.9 0.76 9.5 2.5 2.3 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins Arabino_trans_C PF14896.6 EJP61684.1 - 0.21 10.5 5.2 3.9 6.4 1.2 2.3 1 1 1 2 2 2 0 EmbC C-terminal domain DUF3435 PF11917.8 EJP61685.1 - 8.5e-40 136.9 9.1 5.1e-24 85.0 2.2 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3435) zf-C2H2_12 PF18658.1 EJP61685.1 - 0.03 13.9 0.9 0.37 10.4 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type FOXP-CC PF16159.5 EJP61685.1 - 1.6 9.4 5.2 2.1 9.0 2.2 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain RVT_1 PF00078.27 EJP61690.1 - 7.3e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EJP61690.1 - 0.051 14.3 0.2 0.17 12.7 0.2 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF3435 PF11917.8 EJP61692.1 - 4.2e-93 312.5 0.3 4.2e-93 312.5 0.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3435) Trypsin PF00089.26 EJP61693.1 - 9.9e-45 153.0 0.2 1.2e-44 152.7 0.2 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP61693.1 - 5e-08 34.0 0.5 8e-08 33.3 0.5 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Fungal_trans_2 PF11951.8 EJP61694.1 - 2.7e-12 46.2 1.1 5.5e-12 45.2 1.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain V_ATPase_I PF01496.19 EJP61694.1 - 0.28 9.0 0.0 0.28 9.0 0.0 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Roughex PF06020.11 EJP61694.1 - 0.91 8.6 4.4 1.4 7.9 4.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Sugar_tr PF00083.24 EJP61695.1 - 2.4e-113 379.4 25.4 6.8e-113 377.9 25.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP61695.1 - 3.1e-23 82.3 88.9 2.5e-21 76.0 49.8 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Nop52 PF05997.12 EJP61695.1 - 0.043 13.6 0.1 0.076 12.8 0.1 1.3 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Zn_clus PF00172.18 EJP61696.1 - 1.5e-07 31.4 12.0 2.8e-07 30.6 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain peroxidase PF00141.23 EJP61697.1 - 2.2e-86 289.3 0.0 2.9e-46 158.0 0.0 2.2 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 EJP61697.1 - 0.014 15.5 0.0 3.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain CFEM PF05730.11 EJP61698.1 - 1.3e-12 47.6 9.9 2.3e-12 46.8 9.9 1.4 1 0 0 1 1 1 1 CFEM domain Phage_lysis PF03245.13 EJP61698.1 - 5.5 7.1 8.8 4.7 7.3 1.7 2.8 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein LIDHydrolase PF10230.9 EJP61699.1 - 3.9e-53 180.7 0.0 5.4e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EJP61699.1 - 0.00052 20.7 1.4 0.0011 19.6 1.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP61699.1 - 0.13 11.5 0.0 0.68 9.1 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ank_2 PF12796.7 EJP61701.1 - 4.2e-08 33.7 0.0 0.0064 17.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP61701.1 - 3.3e-06 27.6 0.0 0.024 15.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP61701.1 - 0.00025 21.3 0.0 0.31 11.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP61701.1 - 0.0006 20.1 0.0 15 6.5 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EJP61701.1 - 0.01 16.3 0.0 20 5.9 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat CpcD PF01383.21 EJP61701.1 - 0.13 12.5 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain Ribosomal_S26e PF01283.19 EJP61701.1 - 0.2 12.1 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S26e Enterotoxin_a PF01375.17 EJP61702.1 - 1.1e-18 67.7 0.1 1.8e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain Pertussis_S1 PF02917.14 EJP61702.1 - 0.00011 22.1 0.1 0.00018 21.4 0.1 1.3 1 0 0 1 1 1 1 Pertussis toxin, subunit 1 Abhydrolase_9_N PF15420.6 EJP61702.1 - 0.0014 18.6 0.6 0.0024 17.9 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus pPIWI_RE_REase PF18154.1 EJP61703.1 - 0.13 12.3 0.8 0.28 11.2 0.2 1.8 2 0 0 2 2 2 0 REase associating with pPIWI_RE GGACT PF06094.12 EJP61704.1 - 1.3e-05 25.8 0.0 1.6e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EJP61704.1 - 8e-05 23.0 0.0 0.00096 19.5 0.0 2.1 1 1 0 1 1 1 1 AIG2-like family ChaC PF04752.12 EJP61704.1 - 0.0022 18.1 0.1 0.14 12.2 0.0 2.5 1 1 0 2 2 2 1 ChaC-like protein Amidase PF01425.21 EJP61705.1 - 5.2e-26 91.6 0.0 4.1e-25 88.7 0.0 2.0 1 1 0 1 1 1 1 Amidase Fungal_trans PF04082.18 EJP61706.1 - 2.8e-13 49.5 1.4 4.4e-13 48.9 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EJP61707.1 - 6.9e-30 104.2 61.1 1.1e-28 100.2 60.0 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP61707.1 - 2e-08 33.6 14.4 2e-08 33.6 14.4 3.6 2 1 1 3 3 3 1 Sugar (and other) transporter OmdA PF13376.6 EJP61707.1 - 0.24 11.5 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated TRAM_LAG1_CLN8 PF03798.16 EJP61708.1 - 3.6e-21 75.8 5.1 3.9e-21 75.7 5.1 1.0 1 0 0 1 1 1 1 TLC domain LysM PF01476.20 EJP61709.1 - 8.8e-11 41.7 0.0 0.00052 20.0 0.0 2.6 2 0 0 2 2 2 2 LysM domain Como_LCP PF02247.16 EJP61709.1 - 0.33 9.5 3.2 1.8 7.1 0.4 2.6 3 0 0 3 3 3 0 Large coat protein DUF3439 PF11921.8 EJP61709.1 - 0.46 10.5 15.0 0.054 13.5 6.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HAP2-GCS1 PF10699.9 EJP61709.1 - 0.54 10.3 3.2 1.8 8.6 0.1 3.1 3 0 0 3 3 3 0 Male gamete fusion factor zf-C2H2_4 PF13894.6 EJP61710.1 - 1.9e-16 59.3 51.4 0.06 14.2 0.6 9.3 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP61710.1 - 1.8e-13 50.1 59.4 0.0019 18.6 0.8 9.2 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EJP61710.1 - 4.4e-13 49.1 43.0 0.0043 17.3 1.2 8.8 8 1 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJP61710.1 - 4.8e-13 49.0 45.7 0.029 14.8 0.1 9.1 9 0 0 9 9 9 6 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EJP61710.1 - 0.00015 22.1 41.4 0.0096 16.2 2.7 6.2 3 1 4 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EJP61710.1 - 5.4 7.1 47.0 0.81 9.8 0.4 7.3 8 0 0 8 8 8 0 C2H2-type zinc finger MFS_1 PF07690.16 EJP61711.1 - 1e-28 100.3 24.0 1e-28 100.3 24.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EJP61711.1 - 4e-06 26.4 10.2 7.1e-06 25.6 10.2 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EJP61711.1 - 0.0098 14.8 4.7 0.013 14.4 0.1 2.7 3 1 0 3 3 3 1 MFS_1 like family Gcd10p PF04189.13 EJP61712.1 - 5.6e-122 406.6 0.0 6.6e-122 406.3 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family P21-Arc PF04062.14 EJP61713.1 - 6.5e-74 247.7 0.0 7.5e-74 247.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ADH_N PF08240.12 EJP61714.1 - 1.3e-25 89.3 3.1 2.7e-25 88.4 3.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP61714.1 - 2.6e-20 72.7 0.5 5.2e-20 71.7 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EJP61714.1 - 0.0026 17.3 0.2 0.013 15.0 0.2 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EJP61714.1 - 0.0035 16.7 0.6 0.0062 15.9 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EJP61714.1 - 0.024 14.2 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 EJP61714.1 - 0.042 14.9 0.0 0.076 14.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 EJP61714.1 - 0.044 14.0 0.1 0.081 13.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pep_deformylase PF01327.21 EJP61714.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Polypeptide deformylase EFP PF01132.20 EJP61714.1 - 0.22 11.6 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain MFS_1 PF07690.16 EJP61715.1 - 1.5e-36 126.1 33.2 1.5e-36 126.1 33.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP61715.1 - 0.00028 19.5 2.6 0.00028 19.5 2.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_S7e PF01251.18 EJP61717.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7e TPR_4 PF07721.14 EJP61717.1 - 0.24 12.1 2.1 0.47 11.2 0.8 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HlyIII PF03006.20 EJP61718.1 - 1.9e-47 161.8 24.5 2.5e-47 161.4 24.5 1.2 1 0 0 1 1 1 1 Haemolysin-III related WTF PF03303.13 EJP61718.1 - 0.14 11.8 5.2 0.23 11.2 5.2 1.4 1 0 0 1 1 1 0 WTF protein DUF308 PF03729.13 EJP61718.1 - 0.32 11.3 12.7 1.7 9.1 0.3 4.1 4 1 0 4 4 4 0 Short repeat of unknown function (DUF308) Zn_clus PF00172.18 EJP61720.1 - 6e-08 32.7 10.9 9.7e-08 32.0 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP61720.1 - 5.2e-05 22.2 0.2 7.7e-05 21.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 EJP61721.1 - 1.4e-67 227.3 13.1 1.4e-67 227.3 13.1 1.3 2 0 0 2 2 2 1 RTA1 like protein Insulin_TMD PF17870.1 EJP61721.1 - 0.045 13.8 0.4 1.4 9.0 0.1 3.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment BIV_Env PF05858.12 EJP61721.1 - 0.18 10.0 0.4 0.22 9.7 0.4 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) DUF4293 PF14126.6 EJP61721.1 - 1.4 9.2 8.5 0.51 10.6 3.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Peptidase_M43 PF05572.13 EJP61723.1 - 2.6e-15 56.7 0.0 4.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EJP61723.1 - 0.00031 21.0 0.1 0.00061 20.0 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EJP61723.1 - 0.0079 15.9 0.5 0.028 14.1 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EJP61723.1 - 0.054 14.0 0.4 0.11 13.1 0.4 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EJP61723.1 - 0.083 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 EJP61723.1 - 0.14 12.0 0.2 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EJP61723.1 - 0.2 10.9 0.4 0.34 10.1 0.4 1.3 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 EJP61723.1 - 0.41 9.2 3.3 0.52 8.8 1.0 1.9 2 0 0 2 2 2 0 Putative peptidase family HicA_toxin PF07927.12 EJP61724.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Glyco_transf_25 PF01755.17 EJP61725.1 - 9.6e-14 51.7 0.0 4.6e-10 39.7 0.0 2.3 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Pectate_lyase_3 PF12708.7 EJP61727.1 - 2.8e-75 252.8 12.2 3.9e-66 223.0 7.4 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EJP61727.1 - 6.2e-06 25.8 2.3 0.0099 15.6 0.5 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.6 EJP61727.1 - 1.7e-05 25.2 0.4 0.0012 19.2 0.0 3.3 3 0 0 3 3 3 1 Deoxyribonuclease NucA/NucB CFEM PF05730.11 EJP61728.1 - 2.4e-23 82.0 19.6 4.4e-14 52.3 3.8 5.6 5 0 0 5 5 5 2 CFEM domain DUF3435 PF11917.8 EJP61729.1 - 2.8e-82 276.9 5.4 7e-81 272.3 5.4 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Mpv17_PMP22 PF04117.12 EJP61730.1 - 2.5e-17 62.9 0.1 5.4e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_S8 PF00082.22 EJP61731.1 - 2.6e-38 132.0 0.2 5.8e-38 130.8 0.2 1.6 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EJP61731.1 - 4.8e-07 30.5 0.0 8.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 EJP61731.1 - 0.038 13.9 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 FlgD Ig-like domain GFA PF04828.14 EJP61733.1 - 0.0035 17.6 11.3 0.0039 17.5 0.1 3.4 3 1 1 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 EJP61733.1 - 0.026 14.3 0.2 0.026 14.3 0.2 3.3 5 0 0 5 5 5 0 zinc-ribbon domain DZR PF12773.7 EJP61733.1 - 1.9 8.6 11.2 1 9.4 3.8 3.3 3 1 0 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EJP61733.1 - 6.7 6.3 12.9 0.97 8.9 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain DUF1515 PF07439.11 EJP61734.1 - 0.0006 19.8 3.7 18 5.4 0.1 4.0 1 1 2 4 4 4 3 Protein of unknown function (DUF1515) Dppa2_A PF14049.6 EJP61734.1 - 0.07 13.3 0.9 32 4.8 0.0 3.3 1 1 2 3 3 3 0 Dppa2/4 conserved region in higher vertebrates Gln_amidase PF15644.6 EJP61734.1 - 0.12 13.4 6.4 0.65 11.0 0.5 2.1 1 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase HMG_box_5 PF14887.6 EJP61734.1 - 0.13 12.3 7.3 18 5.4 0.3 3.8 1 1 3 4 4 4 0 HMG (high mobility group) box 5 DUF1428 PF07237.11 EJP61734.1 - 0.84 9.9 9.0 4.2 7.7 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) DUF5372 PF17342.2 EJP61734.1 - 1.4 9.4 6.6 43 4.6 0.6 3.2 1 1 2 3 3 3 0 Family of unknown function (DUF5372) DUF5350 PF17299.2 EJP61734.1 - 9.4 6.8 7.5 55 4.3 0.1 3.2 3 1 1 4 4 4 0 Family of unknown function (DUF5350) Fungal_trans PF04082.18 EJP61736.1 - 7.2e-16 58.0 0.2 1.1e-15 57.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 EJP61737.1 - 1.1e-34 120.6 0.0 1.2e-34 120.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP61737.1 - 5.1e-07 29.8 0.0 2.6e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP61737.1 - 1.2e-06 28.0 0.0 0.00074 18.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP61737.1 - 3e-05 23.5 0.1 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP61737.1 - 0.00033 19.9 0.9 0.049 12.7 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 EJP61737.1 - 0.00075 20.0 0.4 0.007 16.9 0.0 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EJP61737.1 - 0.0032 16.8 0.2 0.21 10.8 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EJP61737.1 - 0.0042 16.4 0.0 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EJP61737.1 - 0.0047 16.2 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EJP61737.1 - 0.006 15.7 0.0 2.9 6.9 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 EJP61737.1 - 0.0078 15.0 0.1 0.44 9.2 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 EJP61737.1 - 0.0078 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EJP61737.1 - 0.02 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EJP61737.1 - 0.02 14.5 0.0 0.11 12.1 0.0 2.2 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 EJP61737.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 EJP61737.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 EJP61737.1 - 0.1 11.9 0.0 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 ThiF family Aldedh PF00171.22 EJP61738.1 - 1.4e-98 330.5 0.0 1.6e-98 330.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease PF00324.21 EJP61739.1 - 1e-98 331.0 40.8 1.3e-98 330.7 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP61739.1 - 2.6e-23 82.6 43.0 2.9e-23 82.4 43.0 1.0 1 0 0 1 1 1 1 Amino acid permease DHDPS PF00701.22 EJP61740.1 - 5.1e-38 130.4 0.0 6e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MR_MLE_C PF13378.6 EJP61740.1 - 0.04 13.5 0.1 0.083 12.4 0.1 1.5 1 0 0 1 1 1 0 Enolase C-terminal domain-like Defensin_2 PF01097.18 EJP61741.1 - 0.015 15.2 12.2 0.049 13.6 0.6 2.3 2 0 0 2 2 2 0 Arthropod defensin Toxin_38 PF14866.6 EJP61741.1 - 0.4 11.0 7.1 1.1 9.7 7.1 1.8 1 1 0 1 1 1 0 Potassium channel toxin P5CR_dimer PF14748.6 EJP61742.1 - 3.7e-27 94.6 6.4 7.7e-27 93.6 6.4 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EJP61742.1 - 9.1e-14 51.8 0.1 9e-13 48.6 0.1 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EJP61742.1 - 0.032 14.5 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sun2_CC2 PF18580.1 EJP61742.1 - 0.48 10.7 2.0 12 6.2 0.1 3.4 4 0 0 4 4 4 0 SUN2 coiled coil domain 2 Pro_dh PF01619.18 EJP61743.1 - 9.8e-60 202.6 0.0 1.1e-59 202.4 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Cellulase PF00150.18 EJP61743.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 EJP61744.1 - 3.9e-30 105.0 30.1 3.9e-30 105.0 30.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_18 PF00704.28 EJP61745.1 - 2.9e-75 253.9 0.2 3.8e-75 253.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 EJP61745.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Nop PF01798.18 EJP61746.1 - 2.9e-83 278.9 0.0 5.3e-83 278.0 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EJP61746.1 - 1.9e-19 69.8 0.0 7.8e-19 67.8 0.0 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain ubiquitin PF00240.23 EJP61747.1 - 4.6e-34 116.0 0.6 7.8e-34 115.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EJP61747.1 - 5.2e-25 87.3 2.0 5.2e-25 87.3 2.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EJP61747.1 - 2.5e-16 59.2 0.7 4.8e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EJP61747.1 - 2.6e-05 24.6 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EJP61747.1 - 0.0012 18.9 0.6 0.0026 17.9 0.6 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EJP61747.1 - 0.004 17.5 0.6 0.0078 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EJP61747.1 - 0.0055 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EJP61747.1 - 0.013 16.0 0.7 0.018 15.6 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EJP61747.1 - 0.02 14.9 1.0 5.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_S26e PF01283.19 EJP61748.1 - 2.2e-52 176.0 9.2 2.7e-52 175.8 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 EJP61748.1 - 0.021 15.4 1.0 0.96 10.1 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf_CopZ PF18423.1 EJP61748.1 - 0.026 14.5 0.4 0.064 13.2 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain SMC_N PF02463.19 EJP61750.1 - 1.2e-77 260.3 0.9 3.3e-77 258.8 0.9 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EJP61750.1 - 1.7e-24 86.3 0.0 7.4e-24 84.3 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EJP61750.1 - 2.6e-12 47.2 0.1 5.3e-05 23.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EJP61750.1 - 2.3e-08 34.8 2.4 2.3e-08 34.8 2.4 6.1 2 2 2 4 4 1 1 AAA domain GAS PF13851.6 EJP61750.1 - 0.00032 20.1 2.0 0.00032 20.1 2.0 7.5 3 2 4 8 8 8 3 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 EJP61750.1 - 0.00067 19.8 5.1 0.00067 19.8 5.1 8.0 4 2 5 9 9 7 1 Tropomyosin like AAA_29 PF13555.6 EJP61750.1 - 0.00083 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 EJP61750.1 - 0.00097 19.4 7.5 0.00097 19.4 7.5 8.8 4 3 4 8 8 7 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EJP61750.1 - 0.0018 17.2 15.4 0.0018 17.2 15.4 7.6 3 2 7 10 10 10 4 Spc7 kinetochore protein ERM PF00769.19 EJP61750.1 - 0.0029 17.5 10.0 0.0029 17.5 10.0 5.5 3 2 3 6 6 4 2 Ezrin/radixin/moesin family IFT57 PF10498.9 EJP61750.1 - 0.0035 16.4 10.9 0.0035 16.4 10.9 5.8 3 2 1 5 5 5 1 Intra-flagellar transport protein 57 DUF16 PF01519.16 EJP61750.1 - 0.006 17.0 0.7 0.006 17.0 0.7 8.8 3 2 3 7 7 6 1 Protein of unknown function DUF16 HemX PF04375.14 EJP61750.1 - 0.0094 15.3 0.4 0.0094 15.3 0.4 7.5 4 2 2 7 7 6 1 HemX, putative uroporphyrinogen-III C-methyltransferase SbcCD_C PF13558.6 EJP61750.1 - 0.072 13.3 0.0 0.71 10.1 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EJP61750.1 - 0.92 9.8 3.3 26 5.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EJP61750.1 - 0.95 10.0 0.0 0.95 10.0 0.0 6.9 4 3 0 4 4 2 0 ABC transporter DUF948 PF06103.11 EJP61750.1 - 8.8 6.7 35.4 3.3 8.0 2.1 7.2 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF948) ELYS PF13934.6 EJP61751.1 - 1.5e-35 123.2 0.0 1.8e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Uteroglobin PF01099.17 EJP61751.1 - 0.18 12.1 0.0 2.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Uteroglobin family Zn_clus PF00172.18 EJP61752.1 - 0.088 13.0 11.2 0.15 12.2 11.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain BcrAD_BadFG PF01869.20 EJP61753.1 - 8.5e-16 58.2 0.7 1.9e-15 57.1 0.7 1.6 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 EJP61753.1 - 3e-05 24.1 0.1 0.00024 21.1 0.0 2.5 2 1 0 2 2 2 1 SIS domain UNC-93 PF05978.16 EJP61754.1 - 2.2e-08 34.0 7.3 2.2e-08 34.0 7.3 2.3 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EJP61754.1 - 9.9e-08 31.3 42.0 9.9e-08 31.3 42.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LapA_dom PF06305.11 EJP61754.1 - 0.28 11.0 0.0 0.28 11.0 0.0 4.4 4 1 1 5 5 5 0 Lipopolysaccharide assembly protein A domain ABC_tran PF00005.27 EJP61755.1 - 2.5e-30 105.8 0.0 2.3e-14 54.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP61755.1 - 1.3e-29 103.7 28.3 2.1e-25 89.9 9.2 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP61755.1 - 2.8e-08 33.5 5.2 0.011 15.2 0.0 4.4 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJP61755.1 - 7.6e-06 26.2 1.6 0.093 13.0 0.0 3.5 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 EJP61755.1 - 2e-05 23.8 0.1 0.16 11.0 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 EJP61755.1 - 0.00017 22.0 0.4 0.076 13.4 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EJP61755.1 - 0.00034 20.5 1.3 1.4 8.7 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP61755.1 - 0.00041 20.0 0.7 0.16 11.7 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP61755.1 - 0.0028 17.6 0.3 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 EJP61755.1 - 0.0029 17.8 0.4 4 7.6 0.3 2.9 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 EJP61755.1 - 0.003 16.9 0.3 0.04 13.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 EJP61755.1 - 0.0033 17.0 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 EJP61755.1 - 0.045 14.1 0.1 5.1 7.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase DEAD PF00270.29 EJP61755.1 - 0.18 11.6 0.2 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF87 PF01935.17 EJP61755.1 - 1 9.4 3.6 2.3 8.3 0.6 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain zf-RING_UBOX PF13445.6 EJP61756.1 - 0.0012 18.8 5.4 0.0036 17.3 5.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EJP61756.1 - 0.014 15.5 4.0 0.014 15.5 4.0 2.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EJP61756.1 - 0.025 14.4 3.6 0.063 13.1 3.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EJP61756.1 - 0.045 14.1 5.8 0.045 14.1 5.8 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 EJP61756.1 - 0.17 11.7 6.6 0.053 13.4 3.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 EJP61756.1 - 0.32 11.3 9.6 0.83 9.9 0.2 3.1 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain DUF3583 PF12126.8 EJP61756.1 - 0.34 10.3 1.7 0.55 9.6 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3583) zf-C3HC4 PF00097.25 EJP61756.1 - 9.9 6.1 11.5 0.53 10.2 5.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Vma12 PF11712.8 EJP61757.1 - 7e-41 139.5 0.0 1.6e-40 138.4 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C2H2_3 PF13878.6 EJP61757.1 - 4e-07 29.7 0.0 7.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO polyprenyl_synt PF00348.17 EJP61758.1 - 2.9e-75 252.6 0.0 4.5e-75 252.0 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EJP61758.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Amidohydro_1 PF01979.20 EJP61759.1 - 2.6e-26 92.7 0.0 4.8e-26 91.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EJP61759.1 - 2.3e-11 43.9 0.1 5e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Kdo PF06293.14 EJP61760.1 - 0.00034 20.0 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP61760.1 - 0.01 15.8 0.1 0.53 10.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.11 EJP61760.1 - 0.025 14.2 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Abhydrolase_6 PF12697.7 EJP61760.1 - 0.098 13.2 0.5 0.17 12.4 0.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1679 PF07914.11 EJP61760.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) ABC_tran PF00005.27 EJP61762.1 - 1e-49 168.6 0.0 2.1e-23 83.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EJP61762.1 - 1.4e-45 155.3 30.0 2.2e-27 95.8 7.8 2.9 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 EJP61762.1 - 9.8e-16 58.4 6.7 0.0015 18.4 0.0 4.9 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EJP61762.1 - 8.4e-10 38.8 1.4 0.00025 21.0 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EJP61762.1 - 2.7e-09 37.6 0.4 0.00049 20.5 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EJP61762.1 - 3.6e-09 36.4 0.2 0.0039 16.7 0.1 4.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJP61762.1 - 2.1e-08 34.5 0.2 0.014 15.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EJP61762.1 - 2.5e-08 34.7 1.6 0.00053 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJP61762.1 - 1.4e-07 31.1 4.1 0.0057 16.4 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EJP61762.1 - 1.4e-06 28.6 0.6 0.011 16.0 0.5 2.8 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 EJP61762.1 - 2.1e-06 27.8 0.0 0.052 13.5 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 EJP61762.1 - 3.8e-06 26.6 0.4 0.08 12.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EJP61762.1 - 6e-06 26.2 0.8 0.66 9.6 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 EJP61762.1 - 1.4e-05 24.9 0.5 0.041 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EJP61762.1 - 2.9e-05 24.4 2.1 0.016 15.5 0.2 3.1 3 1 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 EJP61762.1 - 0.00014 21.3 0.1 0.16 11.3 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SSE PF00437.20 EJP61762.1 - 0.00014 21.0 0.4 0.16 11.0 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_24 PF13479.6 EJP61762.1 - 0.00021 21.1 0.1 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EJP61762.1 - 0.00024 21.1 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea cobW PF02492.19 EJP61762.1 - 0.00038 20.1 1.9 0.53 9.8 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EJP61762.1 - 0.00048 20.5 0.1 1.6 9.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase MMR_HSR1 PF01926.23 EJP61762.1 - 0.00062 19.8 1.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 EJP61762.1 - 0.0014 18.8 0.7 3.4 8.0 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PDR_assoc PF08370.11 EJP61762.1 - 0.0028 17.4 0.1 0.019 14.7 0.2 2.4 2 0 0 2 2 1 1 Plant PDR ABC transporter associated NTPase_1 PF03266.15 EJP61762.1 - 0.0031 17.4 1.8 0.25 11.2 0.3 3.6 4 0 0 4 4 4 1 NTPase AAA_5 PF07728.14 EJP61762.1 - 0.0046 17.0 0.6 6.5 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 EJP61762.1 - 0.0055 16.1 0.2 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATP_bind_1 PF03029.17 EJP61762.1 - 0.0059 16.4 1.0 0.92 9.2 0.2 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein PRK PF00485.18 EJP61762.1 - 0.0063 16.3 0.1 0.58 9.9 0.0 2.5 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EJP61762.1 - 0.0065 17.0 0.1 3.8 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EJP61762.1 - 0.0068 15.9 0.5 0.34 10.3 0.1 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein PhoH PF02562.16 EJP61762.1 - 0.0072 15.8 0.6 1.8 8.0 0.1 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 EJP61762.1 - 0.008 16.3 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EJP61762.1 - 0.0088 15.3 0.5 0.51 9.5 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Roc PF08477.13 EJP61762.1 - 0.019 15.2 0.3 5.8 7.2 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 EJP61762.1 - 0.019 14.8 0.5 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 EJP61762.1 - 0.027 14.2 0.7 4.3 7.0 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein Septin PF00735.18 EJP61762.1 - 0.041 13.2 0.1 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.29 EJP61762.1 - 0.076 13.4 0.7 11 6.5 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 EJP61762.1 - 0.079 12.6 0.8 7.9 6.0 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EJP61762.1 - 0.08 12.1 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 EJP61762.1 - 0.086 12.1 0.3 5.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.9 EJP61762.1 - 0.1 11.4 0.2 2.2 7.0 0.1 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class TsaE PF02367.17 EJP61762.1 - 0.11 12.4 0.4 6.1 6.9 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EJP61762.1 - 0.12 12.4 0.2 12 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJP61762.1 - 0.13 11.8 0.6 16 4.9 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EJP61762.1 - 0.13 12.0 0.2 21 4.9 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 EJP61762.1 - 0.21 12.0 0.3 4 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 EJP61762.1 - 0.26 10.7 0.4 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Cytidylate_kin PF02224.18 EJP61762.1 - 0.35 10.6 1.4 10 5.8 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase DUF87 PF01935.17 EJP61762.1 - 1.6 8.8 5.1 0.81 9.7 0.3 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain AA_permease_2 PF13520.6 EJP61763.1 - 4.1e-46 157.7 48.3 5.6e-46 157.2 48.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP61763.1 - 2.4e-15 56.1 51.6 6.4e-11 41.5 24.1 2.4 2 1 0 2 2 2 2 Amino acid permease Adeno_E3_CR2 PF02439.15 EJP61763.1 - 0.21 11.3 0.0 0.21 11.3 0.0 3.5 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 Epiglycanin_C PF14654.6 EJP61763.1 - 0.73 9.9 0.0 0.73 9.9 0.0 2.7 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region Beta-lactamase PF00144.24 EJP61764.1 - 1.3e-37 129.8 0.1 2e-37 129.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EJP61764.1 - 0.044 14.2 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) PDT PF00800.18 EJP61765.1 - 5.4e-57 192.6 0.1 6.8e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase Tgi2PP PF18250.1 EJP61765.1 - 0.12 12.7 0.0 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Effector immunity protein Tgi2PP Lactonase PF10282.9 EJP61766.1 - 8.5e-29 100.9 0.0 1.2e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EJP61766.1 - 0.0043 16.7 0.0 0.22 11.1 0.0 2.7 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region HofP PF10748.9 EJP61766.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA utilization proteins HofP LysM PF01476.20 EJP61767.1 - 4.6e-25 87.4 0.3 1.1e-06 28.6 0.0 6.5 6 0 0 6 6 6 5 LysM domain DUF1080 PF06439.11 EJP61767.1 - 1.1e-15 58.2 0.2 6e-09 36.3 0.0 3.5 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1080) Intein_splicing PF14890.6 EJP61767.1 - 0.03 14.2 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Intein splicing domain Glyco_hydro_18 PF00704.28 EJP61768.1 - 3.5e-60 204.4 0.0 5.3e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EJP61768.1 - 3.5e-13 49.8 43.9 2.7e-12 47.0 17.0 6.9 7 1 0 7 7 7 2 Chitin recognition protein Peptidase_M18 PF02127.15 EJP61770.1 - 6.3e-117 391.0 0.0 7.2e-117 390.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) BSP PF04450.12 EJP61771.1 - 1.8e-67 227.2 0.0 2e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 EJP61771.1 - 0.11 12.4 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 SprT-like family CLASP_N PF12348.8 EJP61772.1 - 1.5e-131 436.9 2.4 1.2e-85 286.6 0.2 2.6 2 0 0 2 2 2 2 CLASP N terminal DUF4704 PF15787.5 EJP61772.1 - 6.2e-06 25.7 0.7 0.0081 15.4 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4704) HEAT PF02985.22 EJP61772.1 - 0.00012 22.0 0.1 1.7 9.1 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EJP61772.1 - 0.00051 20.1 0.2 1.5 8.9 0.0 4.2 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJP61772.1 - 0.00089 19.6 3.5 0.72 10.3 0.1 4.7 4 1 0 5 5 4 1 HEAT repeats Adaptin_N PF01602.20 EJP61772.1 - 0.022 13.4 0.6 0.92 8.0 0.0 3.1 4 1 1 5 5 5 0 Adaptin N terminal region UNC45-central PF11701.8 EJP61772.1 - 0.037 14.0 0.9 0.35 10.8 0.0 2.7 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Ribosomal_S30 PF04758.14 EJP61772.1 - 0.047 13.9 0.4 0.13 12.5 0.4 1.7 1 0 0 1 1 1 0 Ribosomal protein S30 HEAT_EZ PF13513.6 EJP61772.1 - 0.08 13.5 0.2 42 4.8 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EJP61772.1 - 0.082 13.5 0.0 20 5.9 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF2999 PF11212.8 EJP61772.1 - 0.089 13.1 0.0 0.36 11.2 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Abhydrolase_6 PF12697.7 EJP61773.1 - 4.2e-08 34.1 3.0 1.8e-07 32.0 2.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Siva PF05458.12 EJP61775.1 - 0.54 9.9 3.5 1.1 8.9 3.5 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) RasGAP_C PF03836.15 EJP61777.1 - 0.0087 16.2 1.1 0.021 15.0 1.1 1.6 1 0 0 1 1 1 1 RasGAP C-terminus LIP PF03583.14 EJP61778.1 - 1.2e-61 208.6 0.1 1.8e-61 208.0 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EJP61778.1 - 1.9e-06 27.5 0.6 0.0074 15.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EJP61778.1 - 0.027 13.8 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 EJP61778.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S8 PF00082.22 EJP61779.1 - 6e-28 98.0 7.7 1.6e-27 96.6 7.4 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJP61779.1 - 9.6e-10 39.0 0.1 3.1e-09 37.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF2496 PF10689.9 EJP61780.1 - 0.13 12.1 0.5 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) RabGAP-TBC PF00566.18 EJP61781.1 - 1.1e-26 93.8 1.4 1.8e-26 93.1 1.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf_PR_Knuckle PF18445.1 EJP61781.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 PR zinc knuckle motif Amidohydro_3 PF07969.11 EJP61782.1 - 3.2e-13 50.0 5.0 1.7e-09 37.7 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_1 PF01979.20 EJP61782.1 - 3.3e-11 43.1 0.0 6.7e-10 38.8 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase family DSPc PF00782.20 EJP61784.1 - 6.7e-23 81.0 0.0 8.7e-21 74.1 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJP61784.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UAA PF08449.11 EJP61785.1 - 5.6e-43 147.3 8.7 1.1e-42 146.3 8.7 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EJP61785.1 - 1.3e-08 35.1 26.1 2.2e-06 27.9 5.1 3.4 2 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 EJP61785.1 - 1.7e-05 24.2 1.1 0.092 11.9 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter COX8 PF02285.15 EJP61785.1 - 0.025 14.4 0.0 0.1 12.5 0.0 2.1 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII TPT PF03151.16 EJP61785.1 - 0.03 13.7 7.2 0.77 9.1 1.5 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family CRT-like PF08627.10 EJP61785.1 - 0.14 11.1 3.7 0.65 8.9 0.1 2.3 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like KH_1 PF00013.29 EJP61786.1 - 2.3e-40 136.3 9.8 7.7e-16 57.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EJP61786.1 - 1.4e-09 37.7 9.6 0.013 15.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EJP61786.1 - 2.7e-08 33.6 5.8 0.021 14.7 0.5 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EJP61786.1 - 0.00016 21.7 5.4 0.23 11.5 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain DUF5102 PF17104.5 EJP61787.1 - 0.025 14.7 1.7 0.025 14.7 1.7 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5102) DUF4521 PF15021.6 EJP61787.1 - 0.18 11.7 3.4 0.26 11.2 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4521) GST_C_3 PF14497.6 EJP61788.1 - 1.5e-30 105.3 0.1 2.8e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EJP61788.1 - 7.7e-06 25.8 0.0 9.6e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EJP61788.1 - 0.00064 19.9 0.0 0.0013 18.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EJP61788.1 - 0.039 14.3 0.0 0.23 11.8 0.0 2.4 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain FAM70 PF14967.6 EJP61790.1 - 1.8 7.9 5.7 0.24 10.9 1.7 1.5 2 0 0 2 2 2 0 FAM70 protein NIT PF08376.10 EJP61791.1 - 0.043 14.3 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Nitrate and nitrite sensing DUF1283 PF06932.11 EJP61792.1 - 0.1 12.8 0.2 0.25 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) ANAPC4_WD40 PF12894.7 EJP61793.1 - 3e-05 24.2 0.1 0.081 13.2 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_23 PF13489.6 EJP61794.1 - 1.3e-06 28.4 0.0 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP61794.1 - 0.013 16.1 0.0 0.056 14.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Trypan_PARP PF05887.11 EJP61794.1 - 0.019 15.0 32.9 0.019 15.0 32.9 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Methyltransf_25 PF13649.6 EJP61794.1 - 0.032 14.9 0.3 0.32 11.7 0.2 2.6 2 1 0 2 2 2 0 Methyltransferase domain TonB_N PF16031.5 EJP61794.1 - 2.1 8.9 23.9 4.4 7.8 23.9 1.5 1 0 0 1 1 1 0 TonB polyproline region FAD_binding_3 PF01494.19 EJP61795.1 - 4.3e-19 69.0 0.6 4.6e-11 42.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EJP61795.1 - 2.9e-07 30.0 0.0 0.0083 15.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP61795.1 - 6.1e-06 25.6 1.3 3.3e-05 23.2 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EJP61795.1 - 8.5e-05 22.3 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP61795.1 - 9.8e-05 22.5 0.1 0.00025 21.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EJP61795.1 - 0.00034 20.0 0.1 0.83 8.9 0.1 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EJP61795.1 - 0.0012 17.6 0.0 0.0045 15.7 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EJP61795.1 - 0.0047 16.2 0.0 0.065 12.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 EJP61795.1 - 0.023 14.2 0.0 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 EJP61795.1 - 0.047 12.9 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EJP61795.1 - 0.048 14.2 0.1 0.28 11.7 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EJP61795.1 - 0.064 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase bMG5 PF17972.1 EJP61795.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain Lycopene_cycl PF05834.12 EJP61795.1 - 0.12 11.4 0.2 0.46 9.5 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FMN_dh PF01070.18 EJP61796.1 - 5e-102 341.5 0.0 6.9e-102 341.0 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase COesterase PF00135.28 EJP61796.1 - 9e-79 265.7 0.0 1.2e-78 265.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Cyt-b5 PF00173.28 EJP61796.1 - 4.3e-20 71.6 0.1 8.2e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EJP61796.1 - 1e-06 28.2 0.1 1.6e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EJP61796.1 - 0.00014 21.4 0.1 0.00022 20.7 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Abhydrolase_3 PF07859.13 EJP61796.1 - 0.00018 21.5 0.0 0.00063 19.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold IMPDH PF00478.25 EJP61796.1 - 0.00046 19.3 0.0 0.00079 18.5 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 EJP61796.1 - 0.026 13.8 0.1 3.7 6.8 0.0 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Dus PF01207.17 EJP61796.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 EJP61796.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase Peptidase_M3 PF01432.20 EJP61797.1 - 1.6e-68 232.1 0.1 2.3e-68 231.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 OPT PF03169.15 EJP61797.1 - 4.7e-54 184.1 2.5 6.8e-54 183.6 2.5 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SUV3_C PF12513.8 EJP61799.1 - 1.5e-13 50.4 0.1 5e-13 48.8 0.1 2.0 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 EJP61799.1 - 3.4e-09 36.4 0.6 8.6e-09 35.1 0.2 1.9 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 EJP61799.1 - 4.5e-09 36.6 0.0 1.3e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RsbRD_N PF14361.6 EJP61799.1 - 0.081 13.6 0.2 0.63 10.8 0.1 2.4 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Synaptobrevin PF00957.21 EJP61800.1 - 6.6e-32 109.2 0.6 8.7e-32 108.8 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EJP61800.1 - 6.5e-29 99.8 0.0 1.1e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain FMO-like PF00743.19 EJP61801.1 - 9.4e-07 27.6 0.0 4.8e-06 25.3 0.0 1.8 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Lactamase_B PF00753.27 EJP61802.1 - 7.7e-11 42.4 2.7 1.4e-10 41.6 2.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EJP61802.1 - 0.027 14.0 0.1 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain IDO PF01231.18 EJP61805.1 - 2.9e-33 115.3 0.0 3.7e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase MFS_1 PF07690.16 EJP61806.1 - 2.6e-16 59.5 59.4 2.5e-10 39.8 15.2 3.6 2 1 2 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.13 EJP61806.1 - 2.1e-08 33.1 11.6 2.1e-08 33.1 11.6 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EJP61806.1 - 4.7e-06 25.4 6.6 4.7e-06 25.4 6.6 4.0 4 1 1 5 5 5 2 MFS/sugar transport protein Pox_A14 PF05767.12 EJP61806.1 - 0.17 12.1 3.7 0.38 10.9 0.6 3.1 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 TraQ PF09679.10 EJP61806.1 - 4 7.4 8.2 0.48 10.4 1.4 2.6 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Ferric_reduct PF01794.19 EJP61807.1 - 9.6e-13 48.4 3.0 2.1e-12 47.3 3.0 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EJP61807.1 - 2.2e-09 37.6 0.0 5.6e-05 23.3 0.0 2.3 1 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EJP61807.1 - 1e-07 32.0 0.1 0.0032 17.5 0.1 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 EJP61807.1 - 0.12 13.0 0.0 0.41 11.3 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain CDC14 PF08045.11 EJP61808.1 - 6.9e-123 409.3 0.0 1.3e-63 214.8 0.0 2.1 2 0 0 2 2 2 2 Cell division control protein 14, SIN component Toxin_trans PF07952.12 EJP61811.1 - 0.00011 21.5 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain EF-hand_7 PF13499.6 EJP61812.1 - 3.9e-06 27.2 0.8 6.8e-06 26.5 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EJP61812.1 - 0.00056 19.7 0.0 0.038 13.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EJP61812.1 - 0.0025 17.2 0.0 0.036 13.6 0.0 2.4 2 0 0 2 2 2 1 EF hand TraI_2_C PF07515.11 EJP61812.1 - 0.014 15.3 0.1 0.032 14.2 0.0 1.5 1 1 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term HSM3_N PF18795.1 EJP61812.1 - 0.017 14.5 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain EF-hand_5 PF13202.6 EJP61812.1 - 0.095 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 EF hand polyprenyl_synt PF00348.17 EJP61813.1 - 9.6e-63 211.6 0.0 1.2e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pex24p PF06398.11 EJP61814.1 - 2.7e-82 276.7 0.0 3.1e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pkinase PF00069.25 EJP61815.1 - 5.3e-51 173.5 0.0 8e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61815.1 - 5.3e-18 65.2 0.0 1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GLEYA PF10528.9 EJP61815.1 - 9e-14 51.7 0.2 5.2e-13 49.2 0.2 2.4 1 0 0 1 1 1 1 GLEYA domain APH PF01636.23 EJP61815.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 EJP61817.1 - 4.1e-08 32.5 30.5 0.0002 20.4 28.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3446 PF11928.8 EJP61817.1 - 1.5 9.2 8.5 3.2 8.1 6.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Snf7 PF03357.21 EJP61819.1 - 2.1e-35 121.9 22.2 2.1e-35 121.9 22.2 2.0 1 1 1 2 2 2 1 Snf7 ThrE PF06738.12 EJP61819.1 - 0.18 11.1 0.3 0.26 10.6 0.3 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter RTBV_P46 PF06216.11 EJP61819.1 - 0.2 10.5 0.3 0.26 10.1 0.3 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF4795 PF16043.5 EJP61819.1 - 1.8 8.1 21.8 11 5.6 21.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3138 PF11336.8 EJP61819.1 - 2 7.0 12.8 2.7 6.5 10.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Prefoldin_2 PF01920.20 EJP61819.1 - 2.4 8.2 20.8 0.57 10.2 9.7 3.0 3 0 0 3 3 3 0 Prefoldin subunit Anp1 PF03452.14 EJP61820.1 - 3.1e-111 371.0 0.0 3.9e-111 370.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 DUF3995 PF13160.6 EJP61820.1 - 0.086 13.2 0.2 0.16 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) SRP1_TIP1 PF00660.17 EJP61820.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Seripauperin and TIP1 family HhH-GPD PF00730.25 EJP61821.1 - 6.3e-14 52.3 0.0 2.2e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Recep_L_domain PF01030.24 EJP61822.1 - 1.6e-05 25.0 12.4 0.91 9.7 0.2 5.2 1 1 4 5 5 5 5 Receptor L domain G-patch PF01585.23 EJP61823.1 - 7.2e-12 45.0 0.0 1.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 G-patch domain RCDG1 PF15725.5 EJP61823.1 - 0.038 14.4 0.9 0.038 14.4 0.9 7.1 4 2 3 7 7 7 0 Renal cancer differentiation gene 1 protein PRC PF05239.16 EJP61823.1 - 0.076 13.1 0.3 0.15 12.2 0.3 1.4 1 0 0 1 1 1 0 PRC-barrel domain RRM_1 PF00076.22 EJP61823.1 - 0.21 11.4 0.1 24 4.8 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 EJP61824.1 - 8e-32 110.4 0.0 8.2e-31 107.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP61824.1 - 1e-23 83.8 0.1 3.9e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP61824.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EJP61824.1 - 0.042 14.2 0.0 0.57 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain PrpR_N PF06506.11 EJP61824.1 - 0.094 12.3 0.1 0.61 9.6 0.0 2.2 3 0 0 3 3 3 0 Propionate catabolism activator AAA_22 PF13401.6 EJP61824.1 - 0.23 11.7 0.5 3.9 7.8 0.5 2.7 2 1 0 2 2 2 0 AAA domain Ribosomal_L22e PF01776.17 EJP61827.1 - 2.6e-45 153.3 1.5 3.2e-45 153.0 1.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family dDENN PF03455.19 EJP61827.1 - 0.073 13.1 0.2 0.38 10.8 0.0 2.2 2 1 0 2 2 2 0 dDENN domain Mito_carr PF00153.27 EJP61828.1 - 1.1e-50 169.5 0.1 9.8e-16 57.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Thioesterase PF00975.20 EJP61829.1 - 4.8e-14 53.0 0.1 6.8e-13 49.3 0.1 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EJP61829.1 - 8.2e-05 23.3 2.6 0.00013 22.6 2.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EJP61829.1 - 0.025 14.4 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EJP61829.1 - 0.028 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3918 PF13056.6 EJP61829.1 - 0.36 10.5 2.4 0.69 9.6 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) RRG8 PF17068.5 EJP61830.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial CLP_protease PF00574.23 EJP61831.1 - 9.2e-70 234.2 0.4 1.3e-69 233.8 0.4 1.2 1 0 0 1 1 1 1 Clp protease LOH1CR12 PF10158.9 EJP61831.1 - 0.12 12.4 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Tumour suppressor protein ILVD_EDD PF00920.21 EJP61832.1 - 1.8e-213 709.9 0.1 2e-213 709.7 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family XFP_N PF09364.10 EJP61833.1 - 3.4e-142 473.6 0.0 4.4e-142 473.2 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EJP61833.1 - 3.3e-76 255.2 0.0 4.7e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EJP61833.1 - 5.9e-74 247.6 0.0 9e-74 247.0 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 EJP61833.1 - 0.0023 17.7 0.1 0.011 15.5 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PTPS_related PF10131.9 EJP61833.1 - 0.23 9.8 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Zn_clus PF00172.18 EJP61834.1 - 3e-08 33.7 7.6 7.9e-08 32.3 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetate_kinase PF00871.17 EJP61835.1 - 8.5e-89 298.0 0.0 9.6e-89 297.8 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Egh16-like PF11327.8 EJP61837.1 - 2.1e-62 210.8 4.7 2.6e-62 210.5 4.7 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Cyclin_C_2 PF16899.5 EJP61838.1 - 9.2e-31 106.3 0.7 1.4e-28 99.3 0.3 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EJP61838.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pro-kuma_activ PF09286.11 EJP61839.1 - 4e-42 143.9 0.1 8.7e-42 142.8 0.1 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain AbiEi_3_N PF17194.4 EJP61839.1 - 0.0083 16.1 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin N-terminal domain TPR_2 PF07719.17 EJP61840.1 - 2.2e-07 30.5 9.1 0.00076 19.4 0.4 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJP61840.1 - 3e-05 23.6 2.2 0.19 11.6 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJP61840.1 - 3.1e-05 24.5 2.1 0.015 15.9 1.2 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJP61840.1 - 3.7e-05 23.9 1.1 0.21 11.9 0.2 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP61840.1 - 0.00012 22.0 0.6 0.32 11.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP61840.1 - 0.00067 20.1 0.3 0.026 15.0 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP61840.1 - 0.005 16.3 0.5 0.24 10.8 0.5 2.2 2 0 0 2 2 2 1 MalT-like TPR region TPR_11 PF13414.6 EJP61840.1 - 0.028 14.1 0.4 0.13 12.0 0.3 2.2 2 0 0 2 2 2 0 TPR repeat SPO22 PF08631.10 EJP61840.1 - 0.04 13.4 0.0 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 EJP61840.1 - 0.08 13.6 1.4 5.8 7.8 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP61840.1 - 0.1 13.5 6.2 1.9 9.5 0.6 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribosomal_L13 PF00572.18 EJP61841.1 - 4.1e-12 46.4 0.0 3.3e-10 40.3 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 BAG PF02179.16 EJP61842.1 - 3.2e-18 65.9 0.2 3.2e-18 65.9 0.2 2.2 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.23 EJP61842.1 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Glutaredoxin PF00462.24 EJP61843.1 - 3.1e-18 65.7 0.0 7e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EJP61843.1 - 0.033 14.6 0.1 0.044 14.2 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 EJP61843.1 - 0.083 12.7 0.1 0.39 10.5 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EJP61843.1 - 0.088 13.3 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Chalcone_2 PF16035.5 EJP61844.1 - 1.9e-76 256.4 0.0 4.6e-76 255.2 0.0 1.6 2 0 0 2 2 2 1 Chalcone isomerase like Chalcone_3 PF16036.5 EJP61844.1 - 0.018 15.2 0.3 0.21 11.7 0.2 2.2 1 1 0 2 2 2 0 Chalcone isomerase-like Melibiase PF02065.18 EJP61845.1 - 1.7e-152 507.4 0.0 2.1e-152 507.1 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 EJP61845.1 - 1.5e-77 260.6 0.0 2.2e-77 260.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 EJP61845.1 - 5.6e-21 74.8 0.0 1.1e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 EJP61845.1 - 3e-05 23.2 0.1 5e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 LRR_6 PF13516.6 EJP61846.1 - 7.9e-13 47.3 32.6 0.0058 16.6 0.1 11.9 13 0 0 13 13 13 5 Leucine Rich repeat F-box-like PF12937.7 EJP61846.1 - 2.3e-10 40.2 0.1 7e-10 38.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EJP61846.1 - 2.4e-09 37.3 22.3 1.3 9.5 0.1 7.6 4 2 3 8 8 8 8 Leucine Rich repeats (2 copies) DUF1699 PF08004.11 EJP61846.1 - 0.0016 18.1 0.1 1.2 8.8 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1699) F-box PF00646.33 EJP61846.1 - 0.0077 16.1 0.0 0.038 13.9 0.0 2.3 1 0 0 1 1 1 1 F-box domain Ammonium_transp PF00909.21 EJP61847.1 - 1.2e-116 389.7 29.0 1.4e-116 389.5 29.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pept_tRNA_hydro PF01195.19 EJP61848.1 - 1.2e-24 87.2 0.0 1.4e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.18 EJP61849.1 - 9.1e-64 215.4 4.5 1.1e-63 215.1 4.5 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 EJP61849.1 - 0.0063 17.2 0.0 0.023 15.4 0.0 2.0 1 0 0 1 1 1 1 CP12 domain SVIP PF15811.5 EJP61849.1 - 0.061 13.8 0.4 0.18 12.3 0.4 1.8 1 0 0 1 1 1 0 Small VCP/p97-interacting protein DCP1 PF06058.13 EJP61850.1 - 5.5e-33 113.4 0.0 7.3e-33 113.0 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.23 EJP61851.1 - 2e-06 27.5 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Zn_clus PF00172.18 EJP61852.1 - 2.7e-10 40.2 10.6 4.4e-10 39.5 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP61852.1 - 4e-05 22.8 1.2 0.00016 20.8 1.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Lipase_3 PF01764.25 EJP61853.1 - 1.7e-19 70.1 0.0 3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EJP61853.1 - 0.00016 22.3 6.2 0.00016 22.3 6.2 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EJP61853.1 - 0.22 11.2 0.0 0.48 10.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein MIP PF00230.20 EJP61854.1 - 5.4e-32 111.3 5.3 6.7e-32 111.0 5.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4149 PF13664.6 EJP61854.1 - 2.1 8.7 8.5 0.32 11.3 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) T2SSC PF11356.8 EJP61855.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Type II secretion system protein C Cauli_DNA-bind PF03310.13 EJP61856.1 - 0.21 11.7 1.9 0.21 11.7 0.3 1.8 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein UTRA PF07702.13 EJP61858.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 UTRA domain Peptidase_M49 PF03571.15 EJP61858.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M49 cIII PF08134.11 EJP61859.1 - 0.54 10.0 1.6 1.2 9.0 1.6 1.5 1 0 0 1 1 1 0 cIII protein family Dynamin_N PF00350.23 EJP61860.1 - 9.2e-23 81.1 0.0 6.7e-22 78.3 0.0 2.3 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EJP61860.1 - 1.3e-20 73.9 0.1 3.2e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 EJP61860.1 - 0.0092 16.1 0.0 0.039 14.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_15 PF13175.6 EJP61860.1 - 0.013 15.2 0.0 0.063 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 EJP61860.1 - 0.017 14.9 0.0 0.075 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EJP61860.1 - 0.021 15.0 0.8 0.22 11.7 0.2 2.7 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EJP61860.1 - 0.045 14.3 0.1 0.32 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EJP61860.1 - 0.059 13.5 0.0 0.37 10.9 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EJP61860.1 - 0.082 13.4 0.0 0.33 11.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Pilus_CpaD PF09476.10 EJP61860.1 - 0.18 11.5 0.3 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Aminotran_3 PF00202.21 EJP61862.1 - 6.7e-42 143.6 0.0 8.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PNP_UDP_1 PF01048.20 EJP61867.1 - 7.4e-10 38.5 0.2 2.3e-09 36.9 0.2 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily DUF3188 PF11384.8 EJP61867.1 - 0.086 12.6 3.2 3.8 7.3 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3188) RVT_1 PF00078.27 EJP61868.1 - 7e-18 65.0 0.0 9.3e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaxin PF00804.25 EJP61869.1 - 3e-07 30.3 9.6 0.00019 21.2 1.1 3.1 2 1 1 3 3 3 2 Syntaxin Syntaxin_2 PF14523.6 EJP61869.1 - 0.0048 17.2 4.7 0.045 14.1 0.4 2.3 2 0 0 2 2 2 2 Syntaxin-like protein DUF1043 PF06295.12 EJP61869.1 - 0.071 13.1 0.5 0.18 11.8 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) TPR_12 PF13424.6 EJP61870.1 - 9e-32 109.2 8.7 1.5e-10 41.2 0.0 6.4 4 1 1 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 EJP61870.1 - 3.6e-22 77.5 10.7 3.5e-06 26.7 0.5 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EJP61870.1 - 1.7e-16 58.9 6.6 0.073 13.2 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EJP61870.1 - 2.9e-16 58.5 0.4 0.0029 17.3 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP61870.1 - 1.2e-15 57.7 12.5 1.3e-05 24.8 1.6 4.1 1 1 3 4 4 4 4 MalT-like TPR region TPR_7 PF13176.6 EJP61870.1 - 2.5e-11 42.8 2.4 0.31 11.2 0.1 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJP61870.1 - 1.8e-10 41.3 7.6 0.028 15.0 0.0 6.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP61870.1 - 6.2e-09 35.9 4.6 0.58 11.1 0.1 7.5 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJP61870.1 - 1.3e-08 34.3 7.0 0.25 11.7 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 EJP61870.1 - 3.6e-08 33.3 1.9 0.7 10.7 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP61870.1 - 4e-06 27.3 6.8 3.2 8.3 0.3 5.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJP61870.1 - 0.0018 17.9 5.3 11 5.8 0.1 5.5 6 0 0 6 6 6 1 TPR repeat TPR_6 PF13174.6 EJP61870.1 - 0.0047 17.5 4.9 34 5.4 0.1 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat RPN7 PF10602.9 EJP61870.1 - 0.01 15.6 0.3 0.41 10.3 0.1 2.9 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_17 PF13431.6 EJP61870.1 - 0.019 15.3 1.2 52 4.6 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat FMO-like PF00743.19 EJP61871.1 - 7.2e-20 70.9 0.3 3.1e-11 42.4 0.1 3.2 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EJP61871.1 - 5.6e-08 32.3 0.1 8.3e-07 28.4 0.1 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EJP61871.1 - 4e-07 29.6 0.1 3.6e-06 26.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP61871.1 - 1.9e-06 27.3 0.2 4.9e-05 22.7 0.7 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP61871.1 - 6.9e-05 23.0 0.6 0.0004 20.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EJP61871.1 - 0.00012 22.1 0.1 0.0024 17.9 0.0 2.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 EJP61871.1 - 0.0003 20.5 0.8 0.38 10.3 0.2 3.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 EJP61871.1 - 0.14 11.4 0.4 7.2 5.8 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Glyco_hydro_18 PF00704.28 EJP61872.1 - 0.0044 16.8 0.0 0.0047 16.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SLT PF01464.20 EJP61874.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Transglycosylase SLT domain DUF3716 PF12511.8 EJP61876.1 - 3.7e-08 33.3 2.6 7e-08 32.4 2.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Methyltransf_23 PF13489.6 EJP61880.1 - 1.1e-19 70.9 0.0 1.4e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP61880.1 - 2e-15 57.3 0.0 3.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP61880.1 - 2.4e-15 57.0 0.0 4.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP61880.1 - 8.8e-14 51.6 0.0 9.7e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP61880.1 - 2.2e-13 50.7 0.0 3.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP61880.1 - 7.7e-06 25.4 0.0 9.3e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 EJP61880.1 - 2.1e-05 23.8 0.0 3.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase tRNA_U5-meth_tr PF05958.11 EJP61880.1 - 8.8e-05 21.6 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 EJP61880.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) DUF938 PF06080.12 EJP61880.1 - 0.0027 17.5 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PCMT PF01135.19 EJP61880.1 - 0.0079 16.0 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EJP61880.1 - 0.023 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 EJP61880.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Pkinase_fungal PF17667.1 EJP61881.1 - 2.7e-102 342.6 0.0 3.5e-102 342.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EJP61881.1 - 8.4e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EJP61881.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3925 PF13063.6 EJP61881.1 - 0.22 11.7 0.9 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) Cofilin_ADF PF00241.20 EJP61882.1 - 3.4e-22 78.5 0.0 3.8e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AA_permease_2 PF13520.6 EJP61883.1 - 9.2e-47 159.8 55.2 1.2e-46 159.5 55.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP61883.1 - 4.7e-28 98.0 50.7 5.9e-28 97.7 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 EJP61883.1 - 0.17 11.7 0.7 0.36 10.7 0.7 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) NUDIX_4 PF14815.6 EJP61884.1 - 4.2e-20 71.8 0.1 8.7e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 EJP61884.1 - 4.4e-19 68.9 0.0 9.7e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EJP61884.1 - 1.1e-05 25.1 0.0 3.1e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif IMUP PF15761.5 EJP61884.1 - 4.3 8.1 12.2 11 6.8 12.2 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EJP61884.1 - 5.6 6.5 14.0 10 5.6 14.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rubis-subs-bind PF09273.11 EJP61885.1 - 8.2e-21 75.0 0.0 1.6e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding zf-MYND PF01753.18 EJP61885.1 - 4.6e-10 39.4 10.3 8.4e-10 38.6 10.3 1.4 1 0 0 1 1 1 1 MYND finger SET PF00856.28 EJP61885.1 - 1e-08 35.7 0.0 1.6e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF4523 PF15023.6 EJP61885.1 - 0.085 12.7 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) p450 PF00067.22 EJP61887.1 - 3.8e-49 167.7 0.0 4.9e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C97 PF05903.14 EJP61888.1 - 7.7e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF818 PF05677.12 EJP61888.1 - 0.027 13.5 0.1 0.052 12.5 0.0 1.4 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) DUF4148 PF13663.6 EJP61889.1 - 0.67 10.2 0.1 0.67 10.2 0.1 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) Ferric_reduct PF01794.19 EJP61891.1 - 3.2e-17 62.8 11.8 3.2e-17 62.8 11.8 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EJP61891.1 - 6.5e-12 45.5 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EJP61891.1 - 9.5e-08 32.3 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain VGCC_beta4Aa_N PF12052.8 EJP61891.1 - 0.058 13.5 3.0 0.93 9.6 0.2 2.4 1 1 1 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal ABC_tran PF00005.27 EJP61893.1 - 7e-45 152.9 0.0 3.9e-27 95.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP61893.1 - 4.2e-24 85.7 7.3 1.7e-19 70.5 1.8 3.3 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP61893.1 - 2.2e-11 43.6 0.1 0.00032 20.2 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP61893.1 - 1.1e-06 28.3 0.5 0.025 14.3 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP61893.1 - 1.3e-05 25.7 0.3 0.07 13.5 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EJP61893.1 - 8.9e-05 23.1 0.9 0.32 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EJP61893.1 - 0.00012 22.0 0.1 0.58 10.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EJP61893.1 - 0.00039 20.5 0.2 0.038 14.1 0.1 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EJP61893.1 - 0.0017 18.2 0.5 11 5.7 0.1 3.6 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EJP61893.1 - 0.0018 17.8 0.5 0.24 11.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EJP61893.1 - 0.0028 17.9 1.0 1.7 8.9 0.3 2.9 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EJP61893.1 - 0.0072 15.4 0.2 1.3 8.0 0.2 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.19 EJP61893.1 - 0.0078 15.8 1.0 1.2 8.7 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EJP61893.1 - 0.011 15.8 0.7 0.021 14.9 0.7 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Dynamin_N PF00350.23 EJP61893.1 - 0.016 15.3 0.1 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 EJP61893.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 EJP61893.1 - 0.13 12.0 1.5 15 5.3 0.2 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein CLP1_P PF16575.5 EJP61893.1 - 0.15 11.9 0.2 29 4.4 0.0 3.1 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AIG1 PF04548.16 EJP61893.1 - 0.23 10.8 0.2 1.2 8.4 0.2 2.1 2 0 0 2 2 2 0 AIG1 family SbcCD_C PF13558.6 EJP61893.1 - 0.41 10.9 5.4 2.6 8.3 0.0 4.0 4 0 0 4 4 3 0 Putative exonuclease SbcCD, C subunit DUF4131 PF13567.6 EJP61893.1 - 4.1 7.0 10.4 0.37 10.4 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AA_permease PF00324.21 EJP61894.1 - 1.6e-120 402.9 38.5 2e-120 402.6 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP61894.1 - 1.4e-22 80.2 42.9 1.9e-22 79.7 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease Baculo_PEP_C PF04513.12 EJP61895.1 - 0.0041 17.2 1.4 0.013 15.5 1.4 1.8 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Vps51 PF08700.11 EJP61895.1 - 0.22 11.6 2.2 18 5.5 0.3 3.7 3 0 0 3 3 3 0 Vps51/Vps67 APH PF01636.23 EJP61896.1 - 6.6e-05 22.9 0.1 0.00015 21.8 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP61896.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RINGv PF12906.7 EJP61897.1 - 7.7e-17 61.1 7.7 7.7e-17 61.1 7.7 1.7 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 EJP61897.1 - 0.0022 18.3 8.1 0.004 17.4 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EJP61897.1 - 0.21 11.7 1.7 0.48 10.5 1.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EJP61897.1 - 1.4 8.8 6.8 2.5 7.9 6.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NUDE_C PF04880.13 EJP61898.1 - 3.4e-39 135.1 11.9 3.4e-39 135.1 11.9 4.3 2 1 2 4 4 4 1 NUDE protein, C-terminal conserved region YppF PF14178.6 EJP61898.1 - 0.0084 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 YppF-like protein PSII_Pbs27 PF13326.6 EJP61898.1 - 0.023 15.0 3.7 0.039 14.3 2.8 1.8 2 0 0 2 2 2 0 Photosystem II Pbs27 Fez1 PF06818.15 EJP61898.1 - 0.087 13.3 30.2 0.69 10.3 17.8 3.2 2 1 1 3 3 3 0 Fez1 Tropomyosin_1 PF12718.7 EJP61898.1 - 5 7.3 35.2 2.8 8.1 18.3 3.4 2 1 1 3 3 3 0 Tropomyosin like YabA PF06156.13 EJP61898.1 - 6.3 7.5 22.2 0.7 10.6 7.9 3.5 2 1 2 4 4 4 0 Initiation control protein YabA DUF745 PF05335.13 EJP61898.1 - 8.7 6.0 16.7 0.67 9.6 11.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF745) ACC_central PF08326.12 EJP61899.1 - 2.6e-274 912.0 0.0 3.2e-274 911.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EJP61899.1 - 6.6e-186 618.7 0.0 9e-186 618.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EJP61899.1 - 8.3e-54 182.3 0.0 1.5e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EJP61899.1 - 1.1e-27 96.8 0.1 2.6e-27 95.5 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EJP61899.1 - 9.4e-22 77.2 0.0 1.4e-19 70.1 0.0 2.8 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EJP61899.1 - 1.4e-15 56.8 0.1 3.1e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EJP61899.1 - 5.5e-05 22.8 0.0 0.00017 21.2 0.0 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EJP61899.1 - 0.0014 18.7 0.0 0.0056 16.7 0.0 2.1 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EJP61899.1 - 0.0049 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GxGYxYP_N PF16216.5 EJP61899.1 - 0.006 16.8 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 EJP61899.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon BolA PF01722.18 EJP61900.1 - 3.1e-08 33.8 0.0 5.8e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein Peptidase_S8 PF00082.22 EJP61901.1 - 6.4e-44 150.4 3.4 1.4e-43 149.2 3.4 1.6 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EJP61901.1 - 5.1e-21 75.5 0.1 1.3e-20 74.2 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 EJP61901.1 - 3.7e-07 30.1 0.2 3.8e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.6 EJP61901.1 - 0.00083 19.2 0.4 0.011 15.6 0.0 3.0 3 0 0 3 3 3 1 FlgD Ig-like domain HeLo PF14479.6 EJP61902.1 - 1.7e-05 24.8 0.2 0.023 14.6 0.1 2.7 2 0 0 2 2 2 2 Prion-inhibition and propagation CPSF100_C PF13299.6 EJP61902.1 - 2.7 8.1 6.5 0.33 11.1 1.8 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal NFACT-R_1 PF05670.13 EJP61904.1 - 1.7e-38 131.6 0.2 1.4e-25 90.0 0.0 2.3 1 1 1 2 2 2 2 NFACT protein RNA binding domain Mrx7 PF10906.8 EJP61904.1 - 1.4 9.2 6.7 6.2 7.2 6.7 2.1 1 1 0 1 1 1 0 MIOREX complex component 7 Velvet PF11754.8 EJP61905.1 - 1.7e-05 24.9 0.0 0.0011 18.9 0.0 2.2 1 1 1 2 2 2 2 Velvet factor APH PF01636.23 EJP61906.1 - 7e-10 39.2 0.0 1.3e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Amidase PF01425.21 EJP61907.1 - 3.5e-39 135.0 0.0 5.2e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Peptidase_M24 PF00557.24 EJP61908.1 - 1.2e-49 168.8 0.0 1.6e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EJP61908.1 - 2.2e-26 92.0 0.0 4e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain PGAP1 PF07819.13 EJP61909.1 - 1.3e-06 28.3 0.0 1.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EJP61909.1 - 2.7e-06 28.2 3.9 4.5e-06 27.4 3.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EJP61909.1 - 0.00038 20.0 0.1 0.0022 17.5 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 EJP61909.1 - 0.0043 17.2 0.2 0.0083 16.3 0.2 1.4 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EJP61909.1 - 0.071 12.4 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EJP61909.1 - 0.1 12.4 0.1 0.37 10.6 0.1 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Flavokinase PF01687.17 EJP61910.1 - 1.2e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase MRP-L20 PF12824.7 EJP61910.1 - 0.11 12.7 1.4 0.17 12.0 0.7 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 CBM_21 PF03370.13 EJP61911.1 - 1.8e-30 105.4 0.1 3e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EJP61911.1 - 1e-11 45.2 0.2 2.1e-11 44.3 0.2 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) TPR_2 PF07719.17 EJP61913.1 - 0.00079 19.4 0.8 6.1 7.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJP61913.1 - 0.029 14.5 0.1 0.21 11.7 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EJP61913.1 - 0.048 14.2 0.9 0.048 14.2 0.9 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJP61913.1 - 0.17 12.1 3.6 10 6.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TraC_F_IV PF11130.8 EJP61914.1 - 0.0089 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 F pilus assembly Type-IV secretion system for plasmid transfer PCIF1_WW PF12237.8 EJP61914.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain adh_short PF00106.25 EJP61916.1 - 9.5e-27 93.7 0.6 1.3e-24 86.7 0.5 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EJP61916.1 - 2.5e-17 63.2 0.1 2.6e-16 59.9 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP61916.1 - 1.7e-06 28.0 0.1 2.9e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP61916.1 - 7.4e-05 22.3 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EJP61916.1 - 0.012 14.7 0.1 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EJP61916.1 - 0.013 14.9 0.2 0.045 13.1 0.2 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 EJP61917.1 - 9e-84 281.9 19.1 1e-83 281.7 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP61917.1 - 1.1e-32 113.4 44.5 5.6e-30 104.5 25.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP61917.1 - 2.3e-06 26.3 1.9 4.5e-05 22.1 0.4 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EJP61917.1 - 5.4e-05 21.9 21.2 0.0018 16.9 3.7 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EJP61917.1 - 0.00087 18.2 2.6 0.0015 17.5 0.1 2.4 2 1 1 3 3 3 1 MFS_1 like family IRK PF01007.20 EJP61917.1 - 0.55 10.0 4.9 2.3 8.0 0.4 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Peptidase_S41 PF03572.18 EJP61918.1 - 8.1e-08 32.0 0.0 5.4e-07 29.3 0.0 2.2 2 1 0 2 2 2 1 Peptidase family S41 DUF4413 PF14372.6 EJP61921.1 - 0.03 14.7 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Glyco_hydro_20 PF00728.22 EJP61922.1 - 1.3e-22 80.7 0.6 3.8e-21 75.9 0.3 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Abhydrolase_3 PF07859.13 EJP61922.1 - 4.7e-14 52.8 0.0 7.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 EJP61923.1 - 3.8e-34 118.2 34.3 5.1e-34 117.8 34.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Antifungal_pept PF11410.8 EJP61924.1 - 1.3e-18 66.6 11.4 1.8e-18 66.1 11.4 1.2 1 0 0 1 1 1 1 Antifungal peptide Conotoxin PF02950.17 EJP61924.1 - 0.0022 19.0 1.8 0.0024 18.9 1.8 1.2 1 0 0 1 1 1 1 Conotoxin Fungus-induced PF10917.8 EJP61924.1 - 0.034 14.5 0.1 0.045 14.1 0.1 1.3 1 0 0 1 1 1 0 Fungus-induced protein DUF5633 PF18656.1 EJP61924.1 - 0.048 13.6 0.2 0.081 12.8 0.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5633) Peptidase_M20 PF01546.28 EJP61925.1 - 1e-30 107.0 0.2 2.2e-30 105.9 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJP61925.1 - 7.7e-08 32.2 0.2 1.5e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EJP61925.1 - 0.00067 19.4 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 EJP61926.1 - 6.5e-19 67.9 0.1 8.8e-19 67.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase dimerisation domain LapA_dom PF06305.11 EJP61927.1 - 0.00054 19.7 0.9 0.0078 16.0 0.0 2.6 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DUF3784 PF12650.7 EJP61927.1 - 7.7 6.8 8.3 1 9.6 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) DUF2183 PF09949.9 EJP61928.1 - 1.2e-20 73.7 0.0 2.5e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DEC-1_N PF04625.13 EJP61928.1 - 0.58 9.1 2.6 0.83 8.6 2.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Amidohydro_3 PF07969.11 EJP61929.1 - 5.6e-66 223.9 0.9 6.4e-66 223.7 0.9 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EJP61929.1 - 1.6e-12 47.4 0.1 9.5e-09 35.0 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family Zn_clus PF00172.18 EJP61930.1 - 4.1e-06 26.8 11.9 6.7e-06 26.1 10.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP61930.1 - 4.3e-06 26.0 0.9 7.3e-06 25.2 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.21 EJP61931.1 - 3.3e-89 299.4 0.0 4.5e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EJP61931.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Glyco_transf_25 PF01755.17 EJP61932.1 - 2.9e-14 53.4 0.0 1.5e-13 51.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) HTH_13 PF11972.8 EJP61932.1 - 0.082 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain Enterotoxin_a PF01375.17 EJP61933.1 - 3.6e-20 72.7 0.0 5.4e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain zinc_ribbon_10 PF10058.9 EJP61935.1 - 7.6e-17 60.8 0.1 1.4e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein CCDC-167 PF15188.6 EJP61935.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Pkinase PF00069.25 EJP61936.1 - 2.8e-41 141.6 0.1 7.2e-23 81.3 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61936.1 - 1e-14 54.5 0.3 4.1e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Med26 PF08711.11 EJP61938.1 - 1.4e-12 47.4 0.0 3.2e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Brr6_like_C_C PF10104.9 EJP61939.1 - 1.2e-38 131.9 4.0 1.6e-38 131.5 4.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF3117 PF11314.8 EJP61939.1 - 0.086 12.7 0.4 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) Fungal_trans PF04082.18 EJP61940.1 - 7.9e-23 80.8 2.4 1.3e-22 80.1 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP61940.1 - 2.8e-08 33.8 11.6 6e-08 32.7 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 EJP61942.1 - 0.016 15.6 4.4 0.9 10.0 0.8 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EJP61942.1 - 0.13 13.1 19.2 0.076 13.9 1.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Caskin-Pro-rich PF16907.5 EJP61942.1 - 0.45 11.1 13.7 0.4 11.2 6.7 2.9 2 0 0 2 2 2 0 Proline rich region of Caskin proteins zf-C2H2 PF00096.26 EJP61942.1 - 3 8.5 18.0 0.14 12.7 1.1 3.6 3 1 1 4 4 4 0 Zinc finger, C2H2 type ZZ PF00569.17 EJP61942.1 - 3.1 7.7 8.8 0.59 10.0 3.4 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type Pex16 PF08610.10 EJP61943.1 - 2.5e-140 467.3 0.4 2.8e-140 467.1 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Clr5 PF14420.6 EJP61945.1 - 1.1e-18 67.1 0.3 6.4e-18 64.7 0.1 2.3 2 0 0 2 2 2 1 Clr5 domain FabA PF07977.13 EJP61946.1 - 0.038 13.6 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 FabA-like domain Glyoxalase_3 PF13468.6 EJP61947.1 - 9.2e-20 71.5 0.1 9.5e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase-like domain DUF3859 PF12975.7 EJP61947.1 - 0.048 13.6 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) Cupin_2 PF07883.11 EJP61948.1 - 8.1e-12 44.7 0.0 2.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EJP61948.1 - 0.00013 21.6 0.0 0.03 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EJP61948.1 - 0.002 18.0 0.0 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain EutQ PF06249.12 EJP61948.1 - 0.13 12.1 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ SnoaL PF07366.12 EJP61949.1 - 8.4e-24 83.8 0.0 1e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EJP61949.1 - 3.1e-14 53.4 0.0 4.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Catalase PF00199.19 EJP61953.1 - 9.8e-168 558.2 0.0 1.2e-167 557.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EJP61953.1 - 2.3e-08 34.1 0.0 4.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Fungal_trans_2 PF11951.8 EJP61954.1 - 1.1e-19 70.6 1.4 1.8e-19 69.8 1.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.19 EJP61955.1 - 5.7e-49 167.1 0.0 7.6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP61955.1 - 1.6e-32 113.0 0.0 2.6e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EJP61955.1 - 7.2e-06 25.3 1.3 0.068 12.2 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EJP61955.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EJP61955.1 - 0.0018 18.0 0.1 0.0033 17.1 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EJP61955.1 - 0.0056 16.0 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EJP61955.1 - 0.0068 16.6 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EJP61955.1 - 0.11 11.4 0.3 0.17 10.7 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EJP61955.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase APH PF01636.23 EJP61956.1 - 0.11 12.4 0.4 1.2 9.0 0.4 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 EJP61957.1 - 1.5e-19 71.5 2.6 1.8e-19 71.3 2.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP61957.1 - 2e-19 70.2 0.1 6e-19 68.7 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP61957.1 - 6.6e-09 35.4 0.1 9.3e-09 34.9 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EJP61957.1 - 8.8e-09 34.5 0.0 1.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.11 EJP61957.1 - 0.099 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF1100 PF06500.11 EJP61957.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) zf-LITAF-like PF10601.9 EJP61958.1 - 3.7e-13 49.5 15.9 5.7e-13 48.9 15.9 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.6 EJP61958.1 - 0.0037 17.0 1.8 0.026 14.3 0.9 2.2 2 0 0 2 2 2 1 Cysteine-rich KTR Cupin_1 PF00190.22 EJP61959.1 - 1.2e-38 132.1 0.0 1.2e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EJP61959.1 - 4.3e-25 87.2 4.9 1.2e-12 47.4 0.2 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 EJP61959.1 - 1.6e-07 30.9 0.6 0.012 15.3 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EJP61959.1 - 3.4e-05 23.8 0.8 0.072 13.0 0.2 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain 3-HAO PF06052.12 EJP61959.1 - 0.0081 15.8 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Auxin_BP PF02041.16 EJP61959.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Auxin binding protein SBP56 PF05694.11 EJP61960.1 - 1.8e-07 30.4 0.0 0.0011 17.8 0.0 2.2 2 0 0 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 EJP61960.1 - 0.023 14.0 0.0 5.4 6.2 0.0 2.5 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 EJP61960.1 - 0.14 11.2 0.1 3.5 6.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) HAD_2 PF13419.6 EJP61961.1 - 6.8e-09 36.0 0.0 4.4e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP61961.1 - 4.9e-05 23.7 0.1 0.00024 21.4 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DIOX_N PF14226.6 EJP61962.1 - 5e-30 104.7 0.1 7e-30 104.2 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EJP61962.1 - 5.5e-19 68.5 0.0 1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phosphoesterase PF04185.14 EJP61963.1 - 1.3e-31 110.1 3.9 1.8e-30 106.4 0.8 2.8 1 1 1 2 2 2 2 Phosphoesterase family Abhydrolase_1 PF00561.20 EJP61964.1 - 8.8e-28 97.6 0.1 1.1e-26 94.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP61964.1 - 2.1e-16 61.2 0.1 2.7e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP61964.1 - 8.9e-08 31.7 0.0 8.2e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 EJP61964.1 - 0.084 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family ABC_tran PF00005.27 EJP61967.1 - 2.6e-38 131.6 0.0 1.1e-19 71.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP61967.1 - 1e-23 84.4 12.2 1e-23 84.4 12.2 3.8 3 1 1 4 4 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 EJP61967.1 - 8.4e-09 35.6 0.3 0.0041 17.0 0.0 3.9 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP61967.1 - 1e-07 31.6 0.8 0.0098 15.3 0.1 3.3 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP61967.1 - 3.3e-05 23.5 1.6 0.0028 17.3 0.3 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 EJP61967.1 - 0.00017 21.7 0.3 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family ATP-synt_Z PF16594.5 EJP61967.1 - 0.00041 19.8 0.2 0.0067 15.9 0.1 2.9 2 0 0 2 2 2 1 Putative AtpZ or ATP-synthase-associated MMR_HSR1 PF01926.23 EJP61967.1 - 0.0015 18.6 0.4 0.27 11.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EJP61967.1 - 0.0015 18.9 0.1 16 5.9 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EJP61967.1 - 0.0052 15.9 0.9 0.26 10.3 0.2 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 EJP61967.1 - 0.013 15.9 0.3 14 6.1 0.0 3.6 3 0 0 3 3 3 0 RNA helicase AAA_16 PF13191.6 EJP61967.1 - 0.013 15.8 0.1 9 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EJP61967.1 - 0.04 13.6 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EJP61967.1 - 0.047 14.0 1.0 2.7 8.3 0.2 3.0 2 1 0 2 2 2 0 AAA domain DUF3504 PF12012.8 EJP61967.1 - 0.075 12.9 0.4 0.18 11.7 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) RsgA_GTPase PF03193.16 EJP61967.1 - 0.083 12.8 0.4 7.2 6.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EJP61967.1 - 0.1 11.9 1.0 0.21 10.9 0.3 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EJP61967.1 - 0.14 11.7 1.7 15 5.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EJP61967.1 - 0.18 12.3 0.1 13 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EJP61967.1 - 0.26 11.4 2.7 0.17 12.0 0.3 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain Pkinase PF00069.25 EJP61968.1 - 5e-31 108.0 0.0 2.8e-30 105.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61968.1 - 6.2e-07 29.0 0.1 0.036 13.4 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP61968.1 - 0.013 14.3 0.0 0.028 13.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase dCMP_cyt_deam_1 PF00383.23 EJP61968.1 - 0.18 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Fungal_trans PF04082.18 EJP61969.1 - 6.2e-20 71.3 0.3 1e-19 70.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP61969.1 - 1.5e-07 31.4 16.2 3.2e-07 30.4 16.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_20 PF12840.7 EJP61969.1 - 0.035 14.2 0.1 0.18 11.9 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain NAD_binding_4 PF07993.12 EJP61971.1 - 3.7e-32 111.5 0.0 8.3e-32 110.4 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EJP61971.1 - 3.3e-25 88.5 0.0 1.3e-23 83.3 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme Epimerase PF01370.21 EJP61971.1 - 1.9e-11 43.9 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP61971.1 - 5.9e-06 25.9 0.0 8.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 EJP61971.1 - 0.00012 22.4 0.1 0.00034 20.9 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 EJP61971.1 - 0.00099 19.1 0.0 0.0034 17.3 0.0 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EJP61971.1 - 0.0066 15.6 0.0 0.036 13.2 0.0 2.1 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Glyco_hydro_47 PF01532.20 EJP61973.1 - 4.2e-141 471.0 0.0 4.7e-141 470.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.25 EJP61974.1 - 1.1e-18 67.5 0.0 4e-09 36.2 0.0 2.9 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61974.1 - 1.8e-08 34.0 0.3 0.0058 15.9 0.1 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 EJP61974.1 - 0.0095 15.9 0.3 0.059 13.3 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP61974.1 - 0.065 12.5 0.0 11 5.2 0.0 3.0 4 0 0 4 4 4 0 Kinase-like Kdo PF06293.14 EJP61974.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_3 PF13358.6 EJP61976.1 - 2.8e-22 79.1 0.0 4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EJP61976.1 - 8.9e-07 29.4 0.0 2.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EJP61976.1 - 0.068 13.0 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Isochorismatase PF00857.20 EJP61978.1 - 3.9e-19 69.5 0.1 5.9e-19 68.9 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family Ank_2 PF12796.7 EJP61981.1 - 0.0039 17.8 0.1 0.0079 16.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP61981.1 - 0.095 13.3 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF3435 PF11917.8 EJP61982.1 - 6.8e-60 203.2 0.3 6.8e-60 203.2 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) FAD_binding_4 PF01565.23 EJP61986.1 - 1e-29 103.0 1.8 1.7e-29 102.4 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP61986.1 - 5.4e-09 36.0 0.2 1.2e-08 34.9 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.19 EJP61987.1 - 9.7e-69 232.2 0.0 1.2e-68 231.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EJP61987.1 - 4.9e-31 108.0 0.0 8.9e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EJP61987.1 - 8.7e-07 28.5 0.0 1.8e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP61987.1 - 2.1e-05 24.7 0.1 6.3e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP61987.1 - 4.2e-05 24.0 0.0 0.00012 22.6 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP61987.1 - 6.8e-05 21.7 0.1 0.00011 21.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EJP61987.1 - 0.00051 19.7 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP61987.1 - 0.0025 16.9 0.1 0.008 15.3 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EJP61987.1 - 0.0061 15.9 0.1 0.0099 15.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EJP61987.1 - 0.0063 15.4 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 EJP61987.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EJP61987.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EJP61987.1 - 0.016 14.3 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EJP61987.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EJP61987.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 EJP61987.1 - 0.031 13.3 0.0 0.098 11.7 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase ApbA PF02558.16 EJP61987.1 - 0.038 13.6 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EJP61987.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EJP61987.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EJP61987.1 - 0.18 11.1 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EJP61987.1 - 0.21 11.0 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4174 PF13778.6 EJP61989.1 - 0.065 13.7 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) zf-BED PF02892.15 EJP61990.1 - 0.015 15.3 0.7 0.046 13.8 0.7 1.9 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.6 EJP61990.1 - 0.12 12.2 1.0 0.25 11.1 1.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EJP61990.1 - 0.12 13.2 1.3 0.35 11.8 1.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Dimer_Tnp_hAT PF05699.14 EJP61991.1 - 9.3e-09 35.0 0.1 2.6e-08 33.5 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 EJP61991.1 - 0.00098 19.5 0.1 0.0049 17.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Hva1_TUDOR PF11160.8 EJP61992.1 - 2.4e-05 24.4 0.1 6.7e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain CobU PF02283.16 EJP61992.1 - 0.057 13.0 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DDE_1 PF03184.19 EJP61993.1 - 5.6e-26 91.3 0.0 2.1e-24 86.1 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.6 EJP61993.1 - 0.0007 19.4 0.0 0.0042 16.8 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 EJP61995.1 - 6.8e-60 202.6 0.0 9.5e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP61995.1 - 1.5e-28 99.8 0.0 2.1e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJP61995.1 - 0.00015 20.8 0.0 0.0003 19.9 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EJP61995.1 - 0.001 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EJP61995.1 - 0.0041 16.5 0.1 0.016 14.5 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ALAD PF00490.21 EJP61995.1 - 0.0095 15.1 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Kinase-like PF14531.6 EJP61995.1 - 0.02 14.2 0.0 0.075 12.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 EJP61995.1 - 0.051 13.2 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Dimer_Tnp_hAT PF05699.14 EJP61996.1 - 6.6e-14 51.5 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FtsL PF04999.13 EJP61996.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Cell division protein FtsL p450 PF00067.22 EJP61998.1 - 5.1e-30 104.6 0.0 6.5e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_2 PF13639.6 EJP62001.1 - 1.1e-10 41.7 7.6 2.2e-10 40.7 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJP62001.1 - 9.1e-09 35.0 6.3 1.8e-08 34.1 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJP62001.1 - 5.4e-07 29.2 4.2 1.1e-06 28.2 4.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EJP62001.1 - 6.4e-07 29.6 9.8 3.5e-06 27.2 9.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EJP62001.1 - 8e-07 28.8 6.0 1.8e-06 27.7 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP62001.1 - 1.9e-05 24.6 2.1 3.9e-05 23.6 0.4 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EJP62001.1 - 7.7e-05 22.6 5.5 0.00015 21.7 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EJP62001.1 - 0.0025 17.4 5.4 0.0048 16.5 5.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EJP62001.1 - 0.0067 16.5 5.2 0.022 14.8 5.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EJP62001.1 - 0.0087 16.2 6.7 0.019 15.1 6.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EJP62001.1 - 0.026 14.4 5.7 0.058 13.3 5.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 EJP62001.1 - 0.04 14.0 3.8 0.091 12.9 3.8 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger DUF5348 PF17295.2 EJP62001.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) Prok-RING_4 PF14447.6 EJP62001.1 - 0.16 11.9 6.2 0.45 10.4 6.2 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 E1-E2_ATPase PF00122.20 EJP62002.1 - 2.5e-37 128.2 9.0 5.5e-30 104.2 0.0 3.4 2 1 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EJP62002.1 - 1.2e-27 96.9 8.8 1.2e-27 96.9 8.8 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EJP62002.1 - 1.8e-20 74.2 0.0 1.1e-18 68.4 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJP62002.1 - 5.1e-15 55.3 0.0 1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EJP62002.1 - 2e-14 53.0 1.1 9.1e-14 50.9 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP62002.1 - 8.3e-05 22.4 0.5 0.00021 21.1 0.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UDPG_MGDP_dh_N PF03721.14 EJP62005.1 - 2.8e-10 40.1 0.0 4.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 EJP62005.1 - 0.12 11.9 0.4 0.42 10.1 0.3 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EJP62005.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EJP62005.1 - 0.25 10.6 0.1 0.4 9.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DUF4596 PF15363.6 EJP62005.1 - 6.5 7.1 8.3 0.9 9.8 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) TPR_MLP1_2 PF07926.12 EJP62006.1 - 0.00068 19.7 19.1 0.26 11.4 7.9 3.6 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein Filament PF00038.21 EJP62006.1 - 0.0043 16.7 13.6 0.0071 16.0 13.6 1.3 1 0 0 1 1 1 1 Intermediate filament protein FAM184 PF15665.5 EJP62006.1 - 0.049 13.4 18.4 0.13 12.0 11.1 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B USP8_interact PF08941.10 EJP62006.1 - 0.054 13.3 0.8 0.22 11.3 0.8 2.1 1 0 0 1 1 1 0 USP8 interacting CENP-F_leu_zip PF10473.9 EJP62006.1 - 0.07 13.2 18.6 0.07 13.2 11.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2461 PF09365.10 EJP62006.1 - 0.074 13.0 0.9 0.61 10.0 0.7 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) Sec34 PF04136.15 EJP62006.1 - 0.43 10.4 5.6 0.13 12.1 2.4 1.7 2 0 0 2 2 2 0 Sec34-like family Atg14 PF10186.9 EJP62006.1 - 0.69 8.9 9.6 1.7 7.6 9.6 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KELK PF15796.5 EJP62006.1 - 0.91 10.0 15.9 0.59 10.6 1.9 3.0 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FapA PF03961.13 EJP62006.1 - 1.1 7.7 10.0 1.7 7.1 10.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Macoilin PF09726.9 EJP62006.1 - 2 6.9 15.1 3.1 6.2 15.1 1.2 1 0 0 1 1 1 0 Macoilin family Lectin_N PF03954.14 EJP62006.1 - 3.7 7.3 8.9 18 5.0 1.7 2.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain FliD_N PF02465.18 EJP62006.1 - 5.3 7.8 12.9 46 4.8 0.4 3.6 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF3584 PF12128.8 EJP62006.1 - 6 4.2 19.4 16 2.9 19.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) PRKG1_interact PF15898.5 EJP62006.1 - 6 7.8 17.6 4.7 8.2 1.9 3.3 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain SUKH-4 PF14435.6 EJP62007.1 - 0.033 14.2 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 SUKH-4 immunity protein DUF3435 PF11917.8 EJP62008.1 - 3.9e-31 108.4 1.1 4.6e-31 108.2 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) sCache_like PF16736.5 EJP62008.1 - 0.12 12.5 0.3 0.9 9.7 0.2 2.1 2 0 0 2 2 2 0 Single Cache-like Zn_clus PF00172.18 EJP62009.1 - 9.5e-06 25.6 18.1 9.5e-06 25.6 18.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med9 PF07544.13 EJP62009.1 - 0.094 12.8 0.2 0.27 11.4 0.2 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Dimer_Tnp_hAT PF05699.14 EJP62011.1 - 2.1e-17 62.7 0.9 1.5e-16 60.0 0.0 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Phage_holin_8 PF16931.5 EJP62014.1 - 0.068 13.1 4.5 1.2 9.2 1.5 2.4 2 0 0 2 2 2 0 Putative phage holin Abhydrolase_6 PF12697.7 EJP62017.1 - 0.0024 18.5 0.3 0.0071 17.0 0.1 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP62017.1 - 0.0081 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EJP62017.1 - 0.03 14.2 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase Pkinase PF00069.25 EJP62018.1 - 0.0011 18.4 0.0 0.0038 16.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 EJP62018.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP62018.1 - 0.0096 15.9 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family UCR_TM PF02921.14 EJP62018.1 - 0.06 13.8 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Macro PF01661.21 EJP62018.1 - 0.063 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Macro domain Ank_2 PF12796.7 EJP62020.1 - 1e-30 106.1 0.6 6.2e-14 52.3 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP62020.1 - 4e-27 93.9 6.5 2.8e-08 33.8 0.2 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EJP62020.1 - 5.5e-27 93.8 0.7 9.5e-10 38.8 0.0 4.8 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EJP62020.1 - 6e-24 83.4 9.0 0.00021 21.6 0.1 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EJP62020.1 - 1.8e-21 73.9 5.6 0.008 16.6 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat DUF3723 PF12520.8 EJP62021.1 - 1.2e-05 24.3 0.0 1.2e-05 24.3 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3723) Jnk-SapK_ap_N PF09744.9 EJP62021.1 - 0.011 15.9 4.1 0.011 15.9 4.1 2.6 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Phlebovirus_NSM PF07246.11 EJP62021.1 - 0.44 9.9 9.7 0.52 9.6 3.4 2.5 2 1 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Atg14 PF10186.9 EJP62021.1 - 1.2 8.2 21.5 2.9 6.9 17.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5406 PF17400.2 EJP62021.1 - 1.3 9.4 3.0 7.5 7.0 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5406) APG6_N PF17675.1 EJP62021.1 - 1.8 9.1 36.1 7.1 7.2 7.8 3.2 2 2 0 2 2 2 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 EJP62021.1 - 2.4 7.7 25.0 1.6 8.2 3.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 FapA PF03961.13 EJP62021.1 - 3.1 6.3 14.5 0.55 8.8 0.7 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Hydrophobin PF01185.18 EJP62022.1 - 1.5 9.5 14.8 0.27 11.9 5.3 2.2 1 1 1 2 2 2 0 Fungal hydrophobin DUF3723 PF12520.8 EJP62023.1 - 7.7e-48 163.4 0.0 4.3e-47 161.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) Pkinase PF00069.25 EJP62024.1 - 6.5e-05 22.4 0.0 9.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62024.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MULE PF10551.9 EJP62025.1 - 8.1e-25 87.1 0.0 2e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain FAD_binding_8 PF08022.12 EJP62025.1 - 4.9e-10 39.5 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EJP62025.1 - 0.0025 17.9 0.0 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain AAA PF00004.29 EJP62026.1 - 4.7e-11 43.2 0.0 6.9e-06 26.5 0.0 2.4 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 EJP62026.1 - 3.2e-10 40.3 0.4 7.8e-10 39.0 0.1 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA_16 PF13191.6 EJP62026.1 - 0.1 13.0 0.2 0.22 11.9 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 EJP62026.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 KaiC TAXi_C PF14541.6 EJP62029.1 - 0.081 12.7 0.0 0.098 12.4 0.0 1.1 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal RVT_2 PF07727.14 EJP62030.1 - 2.8e-64 217.1 0.1 3.7e-64 216.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 EJP62031.1 - 7.8e-06 25.7 0.0 2.1e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 GAG-pre-integrase domain Tubulin PF00091.25 EJP62032.1 - 1.7e-62 211.2 0.0 3.2e-62 210.2 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EJP62032.1 - 1.6e-38 131.7 0.0 2.5e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EJP62032.1 - 0.0026 17.4 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EJP62032.1 - 0.018 14.2 0.0 0.064 12.4 0.0 1.8 2 0 0 2 2 2 0 Tubulin like FRQ PF09421.10 EJP62033.1 - 2e-107 360.5 3.9 6e-58 196.7 0.0 2.0 1 1 1 2 2 2 2 Frequency clock protein Rubredoxin_C PF18267.1 EJP62033.1 - 0.009 15.9 0.0 0.48 10.4 0.0 2.7 3 0 0 3 3 3 1 Rubredoxin NAD+ reductase C-terminal domain Metal_resist PF13801.6 EJP62033.1 - 0.099 12.8 1.7 1.1 9.5 0.4 2.4 1 1 1 2 2 2 0 Heavy-metal resistance Zn_clus PF00172.18 EJP62035.1 - 3.7e-07 30.2 14.5 3.7e-07 30.2 14.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NACHT PF05729.12 EJP62037.1 - 1.5e-11 44.5 0.0 3.8e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EJP62037.1 - 5.9e-07 30.0 0.1 1.6e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ank_2 PF12796.7 EJP62037.1 - 2.9e-05 24.6 0.1 0.00047 20.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Abhydrolase_6 PF12697.7 EJP62037.1 - 7.3e-05 23.5 0.4 0.00016 22.3 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.6 EJP62037.1 - 0.00015 22.1 0.1 0.0015 18.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EJP62037.1 - 0.00063 20.2 0.1 0.005 17.3 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EJP62037.1 - 0.00092 19.6 0.0 0.0064 16.9 0.0 2.3 2 0 0 2 2 2 1 RNA helicase Hydrolase_4 PF12146.8 EJP62037.1 - 0.0045 16.3 0.0 0.0094 15.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EJP62037.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) AAA_25 PF13481.6 EJP62037.1 - 0.0047 16.5 0.0 0.032 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EJP62037.1 - 0.0092 15.3 0.0 0.17 11.1 0.0 2.2 1 1 1 2 2 2 1 KAP family P-loop domain RuvB_N PF05496.12 EJP62037.1 - 0.016 14.9 0.0 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Abhydrolase_9 PF10081.9 EJP62037.1 - 0.022 13.8 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Ank_3 PF13606.6 EJP62037.1 - 0.059 13.9 0.1 5.9 7.8 0.0 3.3 2 0 0 2 2 2 0 Ankyrin repeat DUF676 PF05057.14 EJP62037.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF726 PF05277.12 EJP62037.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Cutinase PF01083.22 EJP62037.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase AAA_33 PF13671.6 EJP62037.1 - 0.11 12.6 0.0 0.68 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain LCAT PF02450.15 EJP62037.1 - 0.2 10.8 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3435 PF11917.8 EJP62038.1 - 7.1e-28 97.7 5.5 1.1e-17 64.1 2.6 3.6 2 1 1 3 3 3 3 Protein of unknown function (DUF3435) Phage_int_SAM_5 PF13102.6 EJP62038.1 - 3.1e-05 24.2 1.5 0.00055 20.2 0.9 2.5 2 0 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 EJP62038.1 - 0.03 14.8 1.8 0.048 14.1 0.4 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Init_tRNA_PT PF04179.12 EJP62038.1 - 0.13 12.6 0.0 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 Rit1 DUSP-like domain Retrotrans_gag PF03732.17 EJP62038.1 - 0.31 11.3 1.5 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein TFIIF_alpha PF05793.12 EJP62038.1 - 7.6 5.0 10.4 14 4.1 10.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3253 PF11625.8 EJP62040.1 - 0.044 14.0 0.0 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Myb_DNA-bind_6 PF13921.6 EJP62040.1 - 0.58 10.5 3.2 1.5 9.1 3.2 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pkinase_fungal PF17667.1 EJP62041.1 - 6.9e-124 413.7 0.0 8.8e-124 413.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EJP62041.1 - 5.9e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62041.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase F-box PF00646.33 EJP62042.1 - 0.00087 19.1 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EJP62042.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like Zn_clus PF00172.18 EJP62043.1 - 2.1e-08 34.1 13.7 3.2e-08 33.5 13.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase_polyket PF04673.12 EJP62046.1 - 0.13 12.6 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Polyketide synthesis cyclase Rsd_AlgQ PF04353.13 EJP62048.1 - 0.0032 17.4 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ MFAP1 PF06991.11 EJP62048.1 - 0.01 15.7 16.1 0.012 15.5 16.1 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Tim54 PF11711.8 EJP62048.1 - 0.014 14.2 3.4 0.014 14.2 3.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF3_subunit PF08597.10 EJP62048.1 - 0.021 14.8 10.2 0.023 14.6 10.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Radial_spoke_3 PF06098.11 EJP62048.1 - 0.022 14.0 12.4 0.023 14.0 12.4 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 DUF4770 PF15994.5 EJP62048.1 - 0.091 13.0 2.8 0.1 12.8 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) MIF4G_like_2 PF09090.11 EJP62048.1 - 0.27 10.7 7.4 0.27 10.7 7.4 1.0 1 0 0 1 1 1 0 MIF4G like DUF3584 PF12128.8 EJP62048.1 - 0.5 7.8 14.4 0.58 7.6 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF913 PF06025.12 EJP62048.1 - 1 8.3 5.6 1.2 8.0 5.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Borrelia_P83 PF05262.11 EJP62048.1 - 1.5 7.2 12.7 1.5 7.2 12.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.8 EJP62048.1 - 1.5 7.6 13.2 1.6 7.5 13.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF3_N PF09440.10 EJP62048.1 - 2 8.9 8.0 2.6 8.5 8.0 1.1 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain RNA_pol_Rpc4 PF05132.14 EJP62048.1 - 2.5 8.5 5.5 3.3 8.1 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Casc1_N PF15927.5 EJP62048.1 - 3 7.5 28.1 4.5 6.9 28.1 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus YdfA_immunity PF12127.8 EJP62048.1 - 3.1 6.8 6.3 3.3 6.7 6.3 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial Menin PF05053.13 EJP62048.1 - 3.3 5.9 6.9 3.8 5.8 6.9 1.0 1 0 0 1 1 1 0 Menin DUF390 PF04094.14 EJP62048.1 - 3.4 5.8 18.0 3.8 5.7 18.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) RPN2_C PF18004.1 EJP62048.1 - 4 7.3 13.5 6.3 6.7 13.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hid1 PF12722.7 EJP62048.1 - 4.1 5.4 6.0 4.1 5.4 6.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 EJP62048.1 - 5 5.8 7.8 5 5.8 7.8 1.1 1 0 0 1 1 1 0 Presenilin HSP90 PF00183.18 EJP62048.1 - 7.2 5.4 11.2 9.5 5.0 11.2 1.1 1 0 0 1 1 1 0 Hsp90 protein RR_TM4-6 PF06459.12 EJP62048.1 - 8.9 6.0 13.5 10 5.9 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EJP62048.1 - 9.7 4.3 12.4 11 4.1 12.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3632 PF12311.8 EJP62049.1 - 3.4e-30 105.7 0.0 5.1e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Antifungal_prot PF11402.8 EJP62050.1 - 1.4e-23 82.8 11.3 1.8e-23 82.5 11.3 1.1 1 0 0 1 1 1 1 Antifungal protein DnaJ PF00226.31 EJP62051.1 - 3.1e-23 81.7 2.6 8e-23 80.4 1.7 2.1 2 0 0 2 2 2 1 DnaJ domain RRM_3 PF08777.11 EJP62051.1 - 0.055 13.5 0.1 0.055 13.5 0.1 2.7 2 1 1 3 3 3 0 RNA binding motif DUF724 PF05266.14 EJP62051.1 - 0.1 12.4 10.2 0.33 10.8 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 EJP62051.1 - 0.2 11.7 2.6 0.3 11.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 EJP62051.1 - 0.48 10.9 5.5 0.87 10.1 0.1 2.9 3 0 0 3 3 3 0 Snapin/Pallidin DivIC PF04977.15 EJP62051.1 - 3.2 7.6 6.5 4.6 7.1 0.3 3.5 2 2 1 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 EJP62051.1 - 3.5 6.9 15.3 25 4.1 15.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 EJP62051.1 - 5.6 5.4 8.5 1.7 7.1 4.2 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family Peptidase_M49 PF03571.15 EJP62053.1 - 1.2e-201 670.9 0.0 1.4e-201 670.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 LysM PF01476.20 EJP62055.1 - 6.4e-18 64.6 0.0 9.7e-08 32.0 0.0 3.3 3 0 0 3 3 3 3 LysM domain Glyco_hydro_18 PF00704.28 EJP62058.1 - 1.8e-46 159.3 0.1 3.3e-46 158.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 EJP62058.1 - 5.8e-27 94.0 0.3 2.3e-26 92.0 0.3 2.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Chitin_bind_1 PF00187.19 EJP62058.1 - 4.6e-05 23.8 9.2 4.6e-05 23.8 9.2 3.3 3 0 0 3 3 3 1 Chitin recognition protein LysM PF01476.20 EJP62058.1 - 0.0059 16.6 0.0 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 LysM domain ABC_tran PF00005.27 EJP62059.1 - 0.1 13.1 0.1 0.24 11.9 0.0 1.6 1 1 1 2 2 2 0 ABC transporter Ank_2 PF12796.7 EJP62060.1 - 2.8e-54 181.6 0.0 1.3e-08 35.2 0.0 7.0 4 2 3 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP62060.1 - 5.7e-49 163.5 1.3 1.2e-07 31.8 0.0 8.8 6 2 2 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP62060.1 - 2.3e-42 138.1 0.5 0.00093 19.5 0.0 13.5 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.6 EJP62060.1 - 3.2e-39 132.8 0.1 4.8e-07 30.2 0.0 10.8 6 4 9 15 15 15 11 Ankyrin repeats (many copies) Ank PF00023.30 EJP62060.1 - 1.9e-35 119.7 5.4 0.002 18.5 0.0 12.7 12 0 0 12 12 12 9 Ankyrin repeat FCD PF07729.12 EJP62060.1 - 0.003 18.0 0.1 67 3.9 0.1 5.4 6 1 1 7 7 7 0 FCD domain SesA PF17107.5 EJP62060.1 - 0.065 13.4 0.0 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Shigella_OspC PF06128.11 EJP62060.1 - 0.15 11.7 0.0 9.9 5.8 0.0 3.2 4 0 0 4 4 4 0 Shigella flexneri OspC protein ThiJ_like PF17124.5 EJP62061.1 - 8.6e-45 152.8 0.0 1.1e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 EJP62061.1 - 6.6e-09 35.8 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Amidase PF01425.21 EJP62062.1 - 1.1e-71 242.2 0.0 2.1e-71 241.3 0.0 1.4 1 1 0 1 1 1 1 Amidase EccE PF11203.8 EJP62062.1 - 0.073 13.4 0.0 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE UPF0158 PF03682.13 EJP62063.1 - 0.032 14.2 0.1 0.053 13.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) NifW PF03206.14 EJP62063.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Nitrogen fixation protein NifW adh_short_C2 PF13561.6 EJP62065.1 - 4.1e-31 108.4 0.2 5.1e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP62065.1 - 4.7e-28 98.0 0.1 6.4e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP62065.1 - 8.8e-07 29.0 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP62065.1 - 6.3e-06 25.8 0.0 9.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EJP62065.1 - 0.0014 17.9 0.2 0.0053 16.1 0.0 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 EJP62065.1 - 0.019 14.1 0.3 0.26 10.4 0.3 2.2 1 1 0 1 1 1 0 RmlD substrate binding domain TPP_enzyme_N PF02776.18 EJP62066.1 - 1.7e-33 115.7 0.0 2.3e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EJP62066.1 - 2.9e-14 53.1 0.0 2.2e-13 50.3 0.0 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJP62066.1 - 3.2e-12 46.4 0.0 6.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Zn_clus PF00172.18 EJP62067.1 - 0.0014 18.7 6.2 0.0031 17.6 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_4 PF01063.19 EJP62068.1 - 7.1e-21 75.1 0.0 9.6e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Scytalone_dh PF02982.14 EJP62069.1 - 2.7e-21 76.0 0.0 3.4e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Scytalone dehydratase ABM PF03992.16 EJP62070.1 - 1.4e-11 44.4 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ComGG PF14173.6 EJP62070.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.5 2 0 0 2 2 2 0 ComG operon protein 7 DUF1772 PF08592.11 EJP62071.1 - 3.3e-27 95.5 4.8 4.5e-27 95.0 4.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ECF_trnsprt PF12822.7 EJP62071.1 - 0.004 17.3 3.8 0.0045 17.1 3.8 1.1 1 0 0 1 1 1 1 ECF transporter, substrate-specific component NAD_binding_1 PF00175.21 EJP62072.1 - 4.3e-28 98.1 0.0 6.4e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EJP62072.1 - 3.6e-16 59.3 0.0 6.8e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EJP62072.1 - 2.5e-06 27.7 0.1 0.0082 16.3 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain AA_permease_2 PF13520.6 EJP62073.1 - 1.3e-70 238.4 43.6 1.6e-70 238.1 43.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP62073.1 - 3.5e-18 65.5 42.2 9.6e-18 64.0 42.2 1.6 1 1 0 1 1 1 1 Amino acid permease TMEM237 PF15383.6 EJP62073.1 - 0.04 13.0 0.2 0.11 11.6 0.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 237 SafA PF17073.5 EJP62073.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Two-component-system connector protein Cyt-b5 PF00173.28 EJP62075.1 - 2.5e-13 50.0 0.0 6.2e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acetyltransf_10 PF13673.7 EJP62076.1 - 4.3e-13 49.3 0.0 5.9e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP62076.1 - 2.1e-12 47.3 0.1 2.7e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP62076.1 - 8.1e-11 42.2 0.1 1.4e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP62076.1 - 0.0002 21.5 0.1 0.0005 20.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJP62076.1 - 0.00027 21.1 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP62076.1 - 0.0009 19.2 0.2 0.0016 18.3 0.2 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EJP62076.1 - 0.1 12.8 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase UbiA PF01040.18 EJP62077.1 - 4e-38 131.2 20.3 5.9e-38 130.6 20.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Glyoxalase PF00903.25 EJP62078.1 - 6.7e-11 42.5 0.0 9.1e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EJP62078.1 - 0.00058 20.6 0.8 0.0012 19.6 0.8 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EJP62078.1 - 0.00076 19.7 0.0 0.00084 19.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EJP62078.1 - 0.0017 18.5 1.0 0.005 17.0 1.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain NifZ PF04319.13 EJP62078.1 - 0.12 12.2 0.0 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 NifZ domain zf-C2H2_jaz PF12171.8 EJP62080.1 - 1.1e-13 51.1 33.6 3.6e-05 23.9 1.4 5.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EJP62080.1 - 1e-11 44.6 29.2 0.0095 16.7 0.6 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EJP62080.1 - 1.3e-11 44.2 33.7 0.00016 21.6 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP62080.1 - 5.1e-10 39.3 34.2 0.012 16.0 1.2 6.0 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.7 EJP62080.1 - 7.8e-07 29.3 30.7 0.001 19.4 1.9 5.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EJP62080.1 - 0.00034 20.9 33.6 0.0017 18.7 1.6 5.0 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 EJP62080.1 - 0.0055 17.1 30.0 0.81 10.2 0.6 6.5 7 0 0 7 7 6 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 EJP62080.1 - 0.011 15.4 16.5 1.4 8.8 0.1 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EJP62080.1 - 0.016 15.7 25.7 0.32 11.5 0.1 5.7 3 1 3 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger Spt46 PF17734.1 EJP62080.1 - 0.029 14.2 7.8 0.69 9.7 0.1 3.2 2 1 0 3 3 3 0 Spermatogenesis-associated protein 46 zf-C2HC_2 PF13913.6 EJP62080.1 - 0.051 13.5 12.0 0.56 10.2 0.2 3.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Ribosomal_L44 PF00935.19 EJP62080.1 - 0.091 13.3 1.3 8.8 6.9 0.1 3.1 3 0 0 3 3 3 0 Ribosomal protein L44 zf-DNA_Pol PF08996.10 EJP62080.1 - 0.099 12.4 18.8 0.69 9.6 0.7 3.3 1 1 0 2 2 2 0 DNA Polymerase alpha zinc finger Zn-ribbon_8 PF09723.10 EJP62080.1 - 0.14 12.3 27.3 0.39 10.9 5.1 4.8 2 2 4 6 6 6 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 EJP62080.1 - 0.14 12.0 3.8 1.6 8.6 0.0 3.2 4 0 0 4 4 4 0 Rad50 zinc hook motif Glycolipid_bind PF06475.11 EJP62080.1 - 0.15 11.5 0.4 0.28 10.7 0.4 1.4 1 0 0 1 1 1 0 Putative glycolipid-binding zf_ZIC PF18366.1 EJP62080.1 - 0.28 11.3 13.2 2 8.6 0.0 4.8 5 0 0 5 5 5 0 Zic proteins zinc finger domain zinc-ribbons_6 PF07191.12 EJP62080.1 - 4.9 7.2 19.9 18 5.4 0.4 4.6 3 2 1 4 4 4 0 zinc-ribbons RabGAP-TBC PF00566.18 EJP62082.1 - 2e-35 122.4 0.0 8.7e-18 64.8 0.0 3.4 3 0 0 3 3 3 3 Rab-GTPase-TBC domain UQ_con PF00179.26 EJP62083.1 - 2.2e-38 131.1 0.0 2.5e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP62083.1 - 0.048 13.4 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 EJP62083.1 - 0.075 12.9 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 UEV domain Nop52 PF05997.12 EJP62084.1 - 2.4e-47 161.5 0.0 3.2e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 p450 PF00067.22 EJP62088.1 - 3.5e-71 240.3 0.0 4.4e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4233 PF14017.6 EJP62088.1 - 0.09 13.1 0.1 0.34 11.3 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) CENP-B_dimeris PF09026.10 EJP62089.1 - 0.0037 17.6 4.1 0.0059 17.0 4.1 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EJP62089.1 - 0.03 12.4 4.3 0.039 12.1 4.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Radial_spoke PF04712.12 EJP62089.1 - 0.55 9.1 3.5 0.73 8.7 3.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Cytomega_UL84 PF06284.11 EJP62089.1 - 2.8 6.3 3.5 3.2 6.1 3.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein NOA36 PF06524.12 EJP62089.1 - 4.6 6.5 9.1 6.3 6.0 9.1 1.1 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 EJP62090.1 - 2.3e-30 105.9 0.0 8.5e-30 104.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62090.1 - 3.1e-09 36.5 0.0 1.9e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_3 PF07859.13 EJP62091.1 - 1e-20 74.6 0.0 7.2e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP62091.1 - 1.8e-09 37.0 0.0 4.8e-09 35.6 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase adh_short_C2 PF13561.6 EJP62092.1 - 2.2e-47 161.6 2.6 2.8e-47 161.3 2.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP62092.1 - 8.1e-43 146.1 0.3 1.1e-42 145.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP62092.1 - 4.9e-11 42.9 0.5 6.7e-11 42.4 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP62092.1 - 3.2e-06 26.8 0.3 2.3e-05 24.0 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EJP62092.1 - 0.0061 16.0 0.1 0.013 14.9 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 EJP62092.1 - 0.0065 15.8 0.1 0.014 14.7 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PNGaseA PF12222.8 EJP62092.1 - 0.02 13.7 0.0 0.044 12.7 0.0 1.5 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A 3HCDH_N PF02737.18 EJP62092.1 - 0.075 12.9 0.4 0.17 11.8 0.3 1.7 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 EJP62093.1 - 2.3e-38 132.1 50.5 5.7e-38 130.9 50.5 1.5 1 1 0 1 1 1 1 Amino acid permease KleE PF17394.2 EJP62093.1 - 0.87 9.8 5.8 3.4 7.9 5.8 2.0 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein ABC2_membrane_5 PF13346.6 EJP62093.1 - 8.3 5.9 32.8 0.019 14.5 6.2 3.9 2 1 0 3 3 3 0 ABC-2 family transporter protein Amino_oxidase PF01593.24 EJP62094.1 - 5.1e-57 194.2 0.3 9.6e-57 193.2 0.3 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 EJP62094.1 - 3.8e-16 59.2 0.0 6.7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 EJP62094.1 - 1e-12 48.1 0.3 2.6e-12 46.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP62094.1 - 5.6e-07 29.5 1.1 0.00012 21.8 1.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP62094.1 - 7.7e-06 25.2 2.2 1.9e-05 23.9 2.2 1.7 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EJP62094.1 - 1.1e-05 24.3 0.6 0.0063 15.3 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EJP62094.1 - 1.5e-05 24.4 0.5 8e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EJP62094.1 - 2e-05 24.1 0.9 0.00025 20.5 1.5 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EJP62094.1 - 3.1e-05 23.3 0.0 5.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EJP62094.1 - 0.00012 21.4 0.3 0.058 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP62094.1 - 0.00021 20.5 1.5 0.0011 18.2 0.6 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EJP62094.1 - 0.0035 16.7 0.2 0.0061 15.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EJP62094.1 - 0.017 14.2 0.3 0.053 12.6 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EJP62094.1 - 0.018 14.4 0.6 0.15 11.3 0.2 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EJP62094.1 - 0.032 14.8 0.6 0.068 13.7 0.1 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP62094.1 - 0.12 12.3 1.3 2.3 8.2 0.1 2.6 3 0 0 3 3 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EJP62094.1 - 0.21 11.4 0.2 0.44 10.4 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhyH PF05721.13 EJP62095.1 - 3.7e-34 118.8 0.0 4.8e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ADH_N PF08240.12 EJP62097.1 - 8.5e-17 61.0 0.2 1.1e-16 60.7 0.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EJP62097.1 - 0.035 14.0 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase zinc_ribbon_6 PF14599.6 EJP62097.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon p450 PF00067.22 EJP62098.1 - 5.7e-45 153.9 0.0 7.7e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EJP62099.1 - 5.5e-19 68.2 0.0 8.8e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP62099.1 - 4.5e-07 29.9 2.9 1.2e-06 28.5 2.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CUE PF02845.16 EJP62099.1 - 0.13 12.0 0.1 0.87 9.4 0.1 2.3 2 0 0 2 2 2 0 CUE domain TRI5 PF06330.11 EJP62100.1 - 3.9e-11 42.4 0.3 4.8e-08 32.2 0.0 2.1 1 1 1 2 2 2 2 Trichodiene synthase (TRI5) Trypsin PF00089.26 EJP62101.1 - 8.8e-54 182.6 1.3 1e-53 182.5 1.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP62101.1 - 1.6e-08 35.6 0.4 2.5e-08 35.0 0.4 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 EJP62101.1 - 1.4e-06 28.6 0.0 2.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Pkinase_Tyr PF07714.17 EJP62102.1 - 9.1e-22 77.6 0.0 3.2e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EJP62102.1 - 5e-17 62.1 0.0 1.2e-16 60.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EJP62102.1 - 0.026 13.3 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EJP62102.1 - 0.064 12.6 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S8 PF00082.22 EJP62104.1 - 8e-11 41.7 1.1 2.7e-10 40.0 1.1 1.8 1 1 0 1 1 1 1 Subtilase family DUF4060 PF13269.6 EJP62105.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) Citrate_synt PF00285.21 EJP62108.1 - 1.8e-99 333.3 0.0 2.3e-99 332.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EJP62108.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone CTD_bind PF04818.13 EJP62109.1 - 1.6e-09 38.5 0.0 2.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EJP62109.1 - 3.2e-06 26.9 0.0 7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) E1-E2_ATPase PF00122.20 EJP62110.1 - 1.3e-48 164.9 5.6 1.3e-48 164.9 5.6 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EJP62110.1 - 2.8e-17 63.7 0.1 1.4e-16 61.4 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EJP62110.1 - 3.8e-11 42.5 0.0 8.5e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP62110.1 - 0.0026 17.5 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJP62110.1 - 0.0098 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) OAD_gamma PF04277.13 EJP62110.1 - 1.9 9.2 7.7 6 7.5 1.2 3.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain O-antigen_lig PF13425.6 EJP62110.1 - 3.8 6.2 16.2 0.075 11.8 5.6 2.8 2 1 1 3 3 3 0 O-antigen ligase like membrane protein DUF3425 PF11905.8 EJP62112.1 - 9.7e-19 67.6 0.2 1.7e-18 66.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EJP62112.1 - 0.016 15.3 1.0 0.016 15.3 1.0 1.8 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 EJP62112.1 - 0.16 12.6 2.0 0.35 11.5 2.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA MerR-DNA-bind PF09278.11 EJP62112.1 - 4.9 7.8 16.7 1.5 9.4 0.0 3.8 3 1 1 4 4 4 0 MerR, DNA binding AMP-binding PF00501.28 EJP62113.1 - 1.5e-85 287.3 0.0 2.1e-85 286.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP62113.1 - 5.5e-26 91.3 0.6 5.6e-24 84.9 0.9 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EJP62113.1 - 2e-19 69.2 0.2 4.8e-19 68.0 0.2 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 EJP62113.1 - 0.014 15.4 0.0 0.082 12.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) HET PF06985.11 EJP62114.1 - 7.3e-21 75.1 0.2 1.8e-20 73.7 0.2 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Reprolysin_5 PF13688.6 EJP62115.1 - 1.4e-52 178.7 1.2 1.4e-52 178.7 1.2 2.6 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EJP62115.1 - 1.5e-46 158.7 0.3 3.4e-46 157.6 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EJP62115.1 - 2.7e-44 151.3 0.1 5.6e-44 150.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EJP62115.1 - 9.3e-16 58.4 31.3 9.3e-16 58.4 31.3 4.5 3 2 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EJP62115.1 - 2.4e-10 41.0 0.0 6.2e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 EJP62115.1 - 3.5e-05 24.2 9.1 3.5e-05 24.2 9.1 4.8 1 1 3 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 EJP62115.1 - 0.0022 18.2 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide PROL5-SMR PF15621.6 EJP62115.1 - 0.93 10.1 12.2 4.6 7.8 12.2 2.2 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family NOA36 PF06524.12 EJP62116.1 - 0.67 9.2 17.8 0.4 10.0 13.5 2.0 2 0 0 2 2 2 0 NOA36 protein Myc_N PF01056.18 EJP62116.1 - 7.2 6.4 14.5 0.97 9.3 10.3 1.6 1 1 1 2 2 2 0 Myc amino-terminal region CDC45 PF02724.14 EJP62116.1 - 9.2 4.4 19.0 13 3.9 19.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1751 PF08551.10 EJP62117.1 - 9.8e-28 96.6 4.3 1.9e-27 95.7 4.3 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EJP62117.1 - 0.11 12.5 8.8 0.2 11.6 8.8 1.3 1 0 0 1 1 1 0 Rhomboid family LisH PF08513.11 EJP62118.1 - 8.2e-07 28.8 0.1 1.5e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 EJP62118.1 - 7.1e-06 26.2 0.3 0.038 14.3 0.1 4.7 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJP62118.1 - 3.6e-05 24.4 20.4 0.015 16.1 0.0 7.2 6 2 2 8 8 8 2 WD domain, G-beta repeat Pro_CA PF00484.19 EJP62119.1 - 2.3e-11 44.3 0.2 1.3e-10 41.8 0.2 1.9 1 1 0 1 1 1 1 Carbonic anhydrase TPR_1 PF00515.28 EJP62121.1 - 8.1e-56 183.7 25.0 5.6e-08 32.3 0.1 10.4 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EJP62121.1 - 5.7e-46 151.0 21.7 1.9e-05 24.4 1.1 10.2 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EJP62121.1 - 4.3e-32 107.6 17.8 8.6e-05 22.4 0.0 10.6 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 EJP62121.1 - 4.6e-26 91.2 9.7 1.1e-05 26.0 0.6 7.1 4 2 4 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.6 EJP62121.1 - 3.2e-24 83.5 17.2 0.0025 18.1 0.1 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.6 EJP62121.1 - 4.5e-24 84.5 17.6 2.3e-05 24.6 0.5 7.5 4 4 2 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 EJP62121.1 - 1.4e-23 82.3 26.0 1.6e-06 27.7 0.3 8.9 5 3 3 8 8 8 6 TPR repeat TPR_14 PF13428.6 EJP62121.1 - 1.6e-23 81.3 11.5 0.00023 21.7 0.0 8.7 4 2 5 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 EJP62121.1 - 2.7e-21 75.8 10.9 0.0024 18.4 0.5 7.2 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.6 EJP62121.1 - 1.8e-20 72.1 14.4 0.014 16.0 0.7 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.6 EJP62121.1 - 1.4e-18 66.7 4.2 0.00085 19.4 0.0 6.0 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 EJP62121.1 - 2.1e-18 64.9 10.0 0.011 15.7 0.0 9.4 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_15 PF13429.6 EJP62121.1 - 5.5e-09 35.6 10.2 0.042 13.1 4.5 5.3 1 1 4 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP62121.1 - 8e-09 35.6 7.3 6.5e-07 29.5 1.2 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EJP62121.1 - 4.5e-06 26.5 3.4 0.094 12.4 0.0 4.6 4 2 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 EJP62121.1 - 0.0024 17.7 12.8 7.7 6.5 0.0 7.6 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF2225 PF09986.9 EJP62121.1 - 0.0098 15.6 3.6 0.17 11.6 0.0 3.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.17 EJP62121.1 - 0.021 15.2 8.0 2.5 8.5 0.3 3.6 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 EJP62121.1 - 0.03 14.6 0.3 26 5.3 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EJP62121.1 - 0.048 13.7 0.1 14 5.8 0.0 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.6 EJP62121.1 - 0.56 9.6 10.7 16 4.8 0.3 4.6 2 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 EJP62121.1 - 1.2 9.3 17.6 15 5.8 1.8 6.2 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain AMP-binding PF00501.28 EJP62122.1 - 1.3e-28 99.8 0.0 7.6e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme HTH_25 PF13413.6 EJP62122.1 - 0.033 14.1 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain AMP-binding_C PF13193.6 EJP62122.1 - 0.55 11.3 3.3 2.3 9.3 3.3 2.1 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain CENP-B_dimeris PF09026.10 EJP62122.1 - 4.8 7.6 7.9 9.3 6.7 7.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_L3 PF00297.22 EJP62123.1 - 1.3e-179 596.9 11.5 1.5e-179 596.7 11.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Smg4_UPF3 PF03467.15 EJP62124.1 - 0.0083 16.2 0.4 0.013 15.5 0.4 1.3 1 0 0 1 1 1 1 Smg-4/UPF3 family NuiA PF07924.11 EJP62124.1 - 0.25 11.7 1.0 2.5 8.5 0.1 2.6 2 1 0 2 2 2 0 Nuclease A inhibitor-like protein HAGH_C PF16123.5 EJP62125.1 - 0.075 13.6 0.8 0.16 12.5 0.8 1.5 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Calsarcin PF05556.11 EJP62125.1 - 0.098 12.2 3.6 0.18 11.3 3.6 1.5 1 1 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) 5-FTHF_cyc-lig PF01812.20 EJP62125.1 - 0.11 12.4 2.0 0.25 11.2 2.0 1.5 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family SseC PF04888.12 EJP62125.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family TFIIA PF03153.13 EJP62125.1 - 3.2 7.7 32.0 5.8 6.8 32.0 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EJP62125.1 - 3.3 6.4 6.4 4.7 5.9 6.4 1.3 1 0 0 1 1 1 0 Presenilin DUF5421 PF17458.2 EJP62125.1 - 5.8 6.2 9.4 14 4.9 9.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Chorismate_bind PF00425.18 EJP62126.1 - 1e-90 303.8 0.0 8e-90 300.9 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EJP62126.1 - 2.3e-26 92.7 0.0 7e-22 78.2 0.0 3.7 3 1 0 3 3 3 3 Anthranilate synthase component I, N terminal region adh_short PF00106.25 EJP62129.1 - 1.8e-36 125.5 0.0 2.3e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP62129.1 - 9.1e-23 81.0 0.0 1.2e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP62129.1 - 2.4e-06 27.6 0.0 4.9e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EJP62129.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EJP62129.1 - 0.016 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EJP62129.1 - 0.024 14.9 0.1 0.08 13.2 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Nucleoporin_N PF08801.11 EJP62130.1 - 1.1e-100 337.5 0.5 1.5e-100 337.0 0.5 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EJP62130.1 - 2.5e-52 178.5 0.0 1.1e-51 176.3 0.0 1.8 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF2576 PF10845.8 EJP62130.1 - 0.051 13.2 0.1 0.87 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) Methyltransf_25 PF13649.6 EJP62131.1 - 3.8e-13 49.9 0.1 5.4e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP62131.1 - 4.5e-12 46.5 0.0 1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP62131.1 - 2.8e-11 43.2 0.0 4.1e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EJP62131.1 - 9e-08 32.1 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP62131.1 - 5.4e-05 23.1 0.0 7.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP62131.1 - 5.8e-05 23.8 0.0 0.00016 22.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF5111 PF17138.4 EJP62132.1 - 0.04 13.8 1.7 2.7 7.8 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5111) DUF2781 PF10914.8 EJP62134.1 - 5.1e-30 104.8 0.9 5.7e-30 104.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF4083 PF13314.6 EJP62135.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) RGS PF00615.19 EJP62136.1 - 0.0009 19.5 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pro_dh PF01619.18 EJP62137.1 - 3.4e-60 204.1 0.0 4.5e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Methyltransf_23 PF13489.6 EJP62138.1 - 8.9e-20 71.2 0.0 1.4e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP62138.1 - 6.5e-10 39.6 0.0 2.2e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP62138.1 - 2e-07 31.7 0.2 2.8e-06 28.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP62138.1 - 2e-07 31.6 0.0 3.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP62138.1 - 2.3e-06 27.5 0.0 0.039 13.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 EJP62138.1 - 0.0074 15.8 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EJP62138.1 - 0.016 15.3 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EJP62138.1 - 0.031 13.6 0.0 0.088 12.1 0.0 1.8 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 EJP62138.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 EJP62138.1 - 0.18 11.2 0.0 0.37 10.1 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NUC153 PF08159.12 EJP62139.1 - 1.4e-09 37.6 0.2 1.4e-09 37.6 0.2 3.3 3 0 0 3 3 3 2 NUC153 domain Abhydrolase_3 PF07859.13 EJP62140.1 - 1.9e-17 63.9 0.0 2.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP62140.1 - 3.3e-07 29.5 0.0 1.2e-05 24.3 0.0 2.0 2 0 0 2 2 2 2 Steryl acetyl hydrolase DUF2974 PF11187.8 EJP62140.1 - 0.037 13.6 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 EJP62140.1 - 0.07 12.8 0.0 0.21 11.3 0.0 1.6 1 1 1 2 2 2 0 PGAP1-like protein PNP_phzG_C PF10590.9 EJP62140.1 - 0.95 9.6 3.1 31 4.7 0.1 2.5 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region DEAD PF00270.29 EJP62141.1 - 5.1e-46 156.6 0.0 1.3e-45 155.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP62141.1 - 1.5e-25 89.7 0.0 1.1e-24 86.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EJP62141.1 - 1.4e-20 73.3 0.0 4.1e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Sad1_UNC PF07738.13 EJP62142.1 - 9.3e-09 35.4 0.0 0.00021 21.3 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal IL11 PF07400.11 EJP62142.1 - 0.084 12.5 0.3 0.25 11.0 0.3 1.8 1 0 0 1 1 1 0 Interleukin 11 Epimerase PF01370.21 EJP62143.1 - 3.3e-46 157.7 0.0 4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP62143.1 - 1.6e-45 156.0 0.0 3.1e-45 155.0 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EJP62143.1 - 1.6e-15 56.9 0.0 1.4e-14 53.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EJP62143.1 - 5.1e-13 48.8 0.0 1.8e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EJP62143.1 - 1.9e-12 46.9 0.0 2.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EJP62143.1 - 1.4e-10 41.0 0.0 2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP62143.1 - 2.8e-06 27.4 0.0 5.4e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EJP62143.1 - 4.6e-05 22.7 0.0 0.0052 16.0 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 EJP62143.1 - 0.00021 20.9 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EJP62143.1 - 0.0028 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 EJP62143.1 - 0.041 13.5 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 EJP62143.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 EJP62143.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EJP62144.1 - 6.3e-29 100.6 0.1 6.3e-29 100.6 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP62144.1 - 3.5e-19 70.2 0.2 8.1e-19 69.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP62144.1 - 1.1e-06 28.4 0.0 4.8e-06 26.4 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EJP62144.1 - 0.00026 20.8 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 EJP62144.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ECR1_N PF14382.6 EJP62144.1 - 0.11 12.3 0.3 0.35 10.7 0.3 1.8 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Sec1 PF00995.23 EJP62144.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Sec1 family Peptidase_M3 PF01432.20 EJP62145.1 - 1.6e-132 443.0 0.2 2.1e-132 442.7 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF3201 PF11447.8 EJP62145.1 - 0.09 12.3 0.1 0.68 9.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3201) PHD PF00628.29 EJP62148.1 - 2.4e-09 36.9 1.9 2.4e-09 36.9 1.9 1.8 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EJP62148.1 - 0.008 15.7 2.7 0.013 15.0 2.7 1.4 1 0 0 1 1 1 1 PHD-finger CEBP_ZZ PF16366.5 EJP62148.1 - 0.011 16.0 2.8 0.023 15.0 2.8 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-CW PF07496.15 EJP62148.1 - 0.14 12.2 1.0 0.37 10.8 1.0 1.8 1 0 0 1 1 1 0 CW-type Zinc Finger MMR_HSR1 PF01926.23 EJP62149.1 - 2.1e-13 50.4 0.0 4.6e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP62149.1 - 6.2e-06 26.2 0.4 1.4e-05 25.1 0.4 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EJP62149.1 - 0.0068 15.9 0.2 0.013 15.0 0.2 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EJP62149.1 - 0.0098 16.0 0.1 1.3 9.1 0.1 2.5 1 1 1 2 2 2 1 Dynamin family AAA_18 PF13238.6 EJP62149.1 - 0.11 13.0 0.5 0.35 11.4 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EJP62149.1 - 0.13 12.7 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain HCO3_cotransp PF00955.21 EJP62150.1 - 3.5e-74 250.5 10.2 4.3e-42 144.6 0.2 2.0 1 1 1 2 2 2 2 HCO3- transporter family DUF3341 PF11821.8 EJP62150.1 - 8.8 5.9 8.0 0.69 9.5 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) ADH_zinc_N PF00107.26 EJP62152.1 - 2.2e-16 60.0 0.0 3.7e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP62152.1 - 0.006 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PI3Ka PF00613.20 EJP62153.1 - 6.2e-60 201.8 0.2 1e-59 201.1 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EJP62153.1 - 1.5e-46 159.3 0.1 3.7e-31 108.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EJP62153.1 - 1.2e-29 103.0 0.0 2.1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4336 PF14234.6 EJP62154.1 - 5e-05 22.7 0.4 0.089 12.0 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.10 EJP62155.1 - 1.1e-34 118.5 0.1 2.6e-34 117.3 0.1 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EJP62155.1 - 7.8e-19 67.5 0.1 2.4e-18 66.0 0.1 1.8 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE SnoaL PF07366.12 EJP62157.1 - 8.9e-25 86.9 0.0 1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EJP62157.1 - 1.3e-16 61.1 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EJP62157.1 - 0.045 14.1 0.0 0.065 13.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) ADH_N PF08240.12 EJP62158.1 - 9.3e-23 80.2 2.3 1.5e-22 79.5 2.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP62158.1 - 5e-11 42.7 0.0 8.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EJP62158.1 - 2.4e-05 23.8 0.0 4.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EJP62158.1 - 0.00051 19.4 0.0 0.0011 18.3 0.0 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ETF PF01012.21 EJP62158.1 - 0.089 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein domain WSC PF01822.19 EJP62160.1 - 5.4e-15 55.4 8.7 1.2e-14 54.2 8.7 1.6 1 0 0 1 1 1 1 WSC domain Band_7 PF01145.25 EJP62161.1 - 6.3e-30 104.5 1.0 1.1e-29 103.7 1.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EJP62161.1 - 5.8e-23 80.7 0.4 1.7e-22 79.2 0.4 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 EJP62161.1 - 0.047 13.0 1.4 0.053 12.8 0.2 1.8 2 0 0 2 2 2 0 Poxvirus A11 Protein Band_7_1 PF13421.6 EJP62161.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family UQ_con PF00179.26 EJP62162.1 - 1e-17 64.1 0.0 1.1e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EJP62162.1 - 0.0097 16.2 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain GST_N_3 PF13417.6 EJP62163.1 - 2.8e-17 62.9 0.0 8.1e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP62163.1 - 5.4e-17 61.9 0.1 5e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EJP62163.1 - 9.3e-12 45.1 0.1 1.8e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP62163.1 - 1.1e-07 31.7 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EJP62163.1 - 0.00018 21.7 0.0 0.00035 20.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EJP62163.1 - 0.024 15.2 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain XAP5 PF04921.14 EJP62164.1 - 5.7e-92 308.0 0.0 9e-92 307.4 0.0 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 EJP62164.1 - 0.00062 20.2 3.9 0.00062 20.2 3.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) UPF0564 PF10595.9 EJP62164.1 - 0.08 12.0 0.9 0.13 11.3 0.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 DUF218 PF02698.17 EJP62166.1 - 3.6e-23 82.0 0.0 4.8e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Methyltransf_10 PF05971.12 EJP62167.1 - 3.5e-67 226.8 0.0 5.2e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EJP62167.1 - 0.00061 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EJP62167.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EJP62167.1 - 0.014 14.8 0.1 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 EJP62167.1 - 0.042 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF4139 PF13598.6 EJP62168.1 - 1.8e-30 106.2 0.0 1.6e-29 103.2 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EJP62168.1 - 4.5e-24 84.7 0.1 4.5e-24 84.7 0.1 3.4 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) CDK2AP PF09806.9 EJP62168.1 - 0.23 11.5 4.2 11 6.0 0.1 3.3 3 1 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein DUF4407 PF14362.6 EJP62168.1 - 1.3 8.3 8.4 2.2 7.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_trans PF04082.18 EJP62169.1 - 1.1e-11 44.3 0.0 1.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP62169.1 - 2.1e-05 24.5 7.5 4.5e-05 23.5 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIF_alpha PF05793.12 EJP62169.1 - 0.87 8.1 4.4 1.2 7.6 4.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Myf5 PF12232.8 EJP62169.1 - 7.6 7.4 11.2 4 8.3 4.4 3.1 2 1 0 2 2 2 0 Myogenic determination factor 5 Asp PF00026.23 EJP62170.1 - 1.1e-46 159.7 0.0 1.3e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP62170.1 - 1.8e-11 44.6 0.0 1.3e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EJP62170.1 - 0.071 12.9 0.1 1.2 8.9 0.0 2.7 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Sugar_tr PF00083.24 EJP62171.1 - 3.6e-42 144.8 19.8 9.6e-42 143.4 19.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP62171.1 - 4.4e-32 111.4 28.7 8.7e-27 94.0 10.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.17 EJP62171.1 - 0.00091 19.2 0.2 0.0029 17.6 0.2 1.8 1 0 0 1 1 1 1 Flavivirus non-structural protein NS4A ATG22 PF11700.8 EJP62171.1 - 0.0089 14.7 0.6 0.0089 14.7 0.6 2.3 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like TENA_THI-4 PF03070.16 EJP62173.1 - 3.1e-06 27.1 0.0 0.0071 16.2 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Cwf_Cwc_15 PF04889.12 EJP62173.1 - 0.053 13.3 2.0 0.082 12.6 2.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EJP62173.1 - 0.12 12.8 6.3 0.22 11.9 2.9 2.5 2 1 1 3 3 3 0 Centromere protein B dimerisation domain Ank_2 PF12796.7 EJP62174.1 - 4.5e-48 161.8 0.8 3.3e-15 56.4 0.1 5.3 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP62174.1 - 1.8e-39 133.6 0.8 2.4e-07 31.1 0.0 7.4 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP62174.1 - 1.3e-33 111.2 0.0 0.00051 20.3 0.0 10.2 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 EJP62174.1 - 3.8e-31 106.2 20.3 0.00048 20.5 0.1 9.5 10 0 0 10 10 9 7 Ankyrin repeat Ank_5 PF13857.6 EJP62174.1 - 7.8e-23 80.2 10.5 0.0022 18.2 0.1 8.3 3 3 5 8 8 8 6 Ankyrin repeats (many copies) NACHT PF05729.12 EJP62174.1 - 6.9e-08 32.6 0.7 1.7e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EJP62174.1 - 1.1e-06 29.2 7.7 7.6e-06 26.4 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain NB-ARC PF00931.22 EJP62174.1 - 0.0037 16.5 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EJP62174.1 - 0.05 13.9 0.0 0.32 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Barstar PF01337.18 EJP62174.1 - 0.2 11.7 2.9 0.28 11.2 0.8 2.4 2 0 0 2 2 2 0 Barstar (barnase inhibitor) YfcL PF08891.11 EJP62174.1 - 0.93 9.9 4.1 6 7.3 0.0 3.8 3 0 0 3 3 3 0 YfcL protein HAD_2 PF13419.6 EJP62175.1 - 4.4e-15 56.2 0.0 1.4e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP62175.1 - 3.6e-07 30.7 0.0 2.8e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP62175.1 - 0.0074 16.3 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like TPR_1 PF00515.28 EJP62176.1 - 0.056 13.3 0.3 0.67 9.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP62176.1 - 0.14 13.1 2.6 0.36 11.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EJP62176.1 - 0.22 11.7 4.2 1.1 9.5 0.1 3.2 4 1 0 4 4 4 0 Tetratricopeptide repeat CFEM PF05730.11 EJP62177.1 - 0.0022 18.1 2.0 0.0042 17.2 2.0 1.5 1 0 0 1 1 1 1 CFEM domain WD40 PF00400.32 EJP62178.1 - 6.6e-13 48.9 6.8 5.9e-05 23.8 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP62178.1 - 0.0028 17.9 0.3 6.7 7.1 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain LVIVD PF08309.11 EJP62179.1 - 2.4e-09 36.3 0.0 0.13 11.6 0.0 4.9 5 0 0 5 5 5 4 LVIVD repeat Xlink PF00193.17 EJP62179.1 - 0.08 13.3 1.0 0.54 10.7 0.0 2.5 2 1 1 3 3 3 0 Extracellular link domain MFS_1 PF07690.16 EJP62180.1 - 1.2e-41 142.8 57.0 1.2e-41 142.8 57.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP62180.1 - 4.5e-08 32.4 11.7 4.5e-08 32.4 11.7 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3377 PF11857.8 EJP62180.1 - 0.085 12.8 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PATR PF12951.7 EJP62180.1 - 1.3 9.1 5.7 19 5.4 0.1 3.0 2 0 0 2 2 2 0 Passenger-associated-transport-repeat Inositol_P PF00459.25 EJP62181.1 - 7.8e-37 127.3 0.1 4.6e-36 124.7 0.1 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family Pantoate_ligase PF02569.15 EJP62182.1 - 1.2e-92 309.9 0.0 1.4e-92 309.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Acyltransferase PF01553.21 EJP62183.1 - 1.3e-17 63.6 0.0 2.6e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.16 EJP62184.1 - 6.4e-28 96.5 0.1 1e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 GYF PF02213.16 EJP62185.1 - 6.5e-19 67.3 0.3 1.3e-18 66.3 0.3 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EJP62185.1 - 0.0058 16.4 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 GYF domain 2 TPR_16 PF13432.6 EJP62186.1 - 3.5e-09 37.2 0.3 3.5e-09 37.2 0.3 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP62186.1 - 3.5e-09 36.1 0.1 0.0065 16.2 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJP62186.1 - 1.7e-07 30.8 13.8 0.0013 18.7 0.0 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP62186.1 - 8.3e-06 26.2 0.7 0.002 18.6 0.1 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJP62186.1 - 1.5e-05 25.2 9.4 0.083 13.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP62186.1 - 1.6e-05 24.7 2.0 0.079 13.2 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP62186.1 - 0.0013 18.6 0.2 0.049 13.7 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJP62186.1 - 0.015 15.0 0.0 0.11 12.2 0.0 2.5 2 1 1 3 3 3 0 TPR repeat TPR_9 PF13371.6 EJP62186.1 - 0.033 14.3 0.1 0.17 12.0 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EJP62186.1 - 0.036 13.5 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR ANAPC3 PF12895.7 EJP62186.1 - 0.044 14.0 0.7 0.15 12.3 0.1 2.2 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 WXG100 PF06013.12 EJP62186.1 - 0.83 9.9 4.8 0.23 11.7 0.2 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG TPR_14 PF13428.6 EJP62186.1 - 3.5 8.7 18.1 0.71 10.8 0.1 5.3 4 1 1 5 5 4 0 Tetratricopeptide repeat AP_endonuc_2 PF01261.24 EJP62188.1 - 8.1e-28 97.3 0.1 1.7e-27 96.3 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Carot_N PF09150.10 EJP62188.1 - 0.006 16.5 0.0 0.0095 15.8 0.0 1.2 1 0 0 1 1 1 1 Orange carotenoid protein, N-terminal Reprolysin_5 PF13688.6 EJP62189.1 - 8.7e-05 22.8 0.1 0.00014 22.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EJP62189.1 - 0.00075 20.0 0.1 0.0016 19.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 EJP62189.1 - 0.028 14.4 0.7 0.13 12.2 0.3 2.2 2 1 0 2 2 2 0 Pregnancy-associated plasma protein-A Cupin_2 PF07883.11 EJP62190.1 - 0.002 17.8 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain ABC_tran PF00005.27 EJP62191.1 - 7.5e-49 165.8 0.0 3.5e-26 92.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EJP62191.1 - 5.9e-16 59.1 1.6 1.3e-05 25.2 0.1 4.4 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP62191.1 - 6.5e-13 48.6 0.0 0.00017 21.1 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP62191.1 - 5.2e-09 36.9 1.6 0.00012 22.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain Chromo PF00385.24 EJP62191.1 - 1.6e-08 34.3 0.1 3.2e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 EJP62191.1 - 2.3e-07 30.9 0.0 0.0037 17.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP62191.1 - 3.1e-07 30.5 0.0 0.0026 17.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EJP62191.1 - 5.1e-07 29.3 0.4 0.0074 16.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EJP62191.1 - 1.9e-05 25.0 0.0 0.0014 18.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EJP62191.1 - 3.2e-05 24.2 0.1 0.49 10.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EJP62191.1 - 6.6e-05 23.5 0.0 0.036 14.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EJP62191.1 - 0.00018 21.3 0.0 0.16 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EJP62191.1 - 0.00063 19.9 0.9 0.26 11.4 0.1 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain NACHT PF05729.12 EJP62191.1 - 0.0011 18.9 0.1 1.3 9.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 EJP62191.1 - 0.0021 18.2 0.0 2.8 8.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EJP62191.1 - 0.0021 18.4 0.0 4.1 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 EJP62191.1 - 0.0039 16.9 0.4 1.9 8.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP62191.1 - 0.0044 17.4 0.1 0.65 10.4 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 EJP62191.1 - 0.0061 17.0 0.0 4.4 7.7 0.0 3.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 EJP62191.1 - 0.0063 15.5 0.3 1.6 7.7 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 EJP62191.1 - 0.0064 15.2 0.3 1.4 7.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 EJP62191.1 - 0.0073 16.0 0.4 0.62 9.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EJP62191.1 - 0.0096 16.0 0.0 0.35 10.9 0.0 3.2 4 0 0 4 4 3 1 Dynamin family PduV-EutP PF10662.9 EJP62191.1 - 0.016 14.9 0.0 0.86 9.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SR-25 PF10500.9 EJP62191.1 - 0.028 14.1 2.8 0.049 13.2 2.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NTPase_1 PF03266.15 EJP62191.1 - 0.038 13.9 0.1 18 5.2 0.1 3.5 4 0 0 4 4 4 0 NTPase DUF3584 PF12128.8 EJP62191.1 - 0.044 11.3 1.2 3.4 5.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF815 PF05673.13 EJP62191.1 - 0.047 12.9 0.0 3 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 EJP62191.1 - 0.049 13.2 1.5 7.6 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 EJP62191.1 - 0.05 13.8 0.0 9.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EJP62191.1 - 0.05 13.6 0.0 7.2 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EJP62191.1 - 0.053 12.7 0.1 3 7.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain FAM199X PF15814.5 EJP62191.1 - 0.077 12.0 3.1 0.15 11.1 3.1 1.3 1 0 0 1 1 1 0 Protein family FAM199X Septin PF00735.18 EJP62191.1 - 0.09 12.0 0.0 9.3 5.4 0.0 2.5 2 0 0 2 2 2 0 Septin TsaE PF02367.17 EJP62191.1 - 0.11 12.5 0.3 20 5.2 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLP1_P PF16575.5 EJP62191.1 - 0.11 12.3 0.2 12 5.7 0.0 3.1 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 EJP62191.1 - 0.15 11.6 0.0 15 5.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ALF PF03752.13 EJP62191.1 - 3.8 7.5 8.4 15 5.7 0.7 3.6 4 0 0 4 4 4 0 Short repeats of unknown function DHHC PF01529.20 EJP62192.1 - 1.6e-36 125.4 9.7 1.6e-36 125.4 9.7 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase B12D PF06522.11 EJP62193.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit CD34_antigen PF06365.12 EJP62193.1 - 0.17 11.4 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family HAD PF12710.7 EJP62194.1 - 1.5e-23 84.1 0.3 2.4e-23 83.5 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP62194.1 - 1.5e-17 64.6 0.4 2.8e-17 63.7 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EJP62194.1 - 4.3e-08 33.2 1.0 4.1e-07 30.0 0.1 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EJP62194.1 - 0.00011 22.3 0.0 0.00071 19.7 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 EJP62194.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) TPPII_N PF12583.8 EJP62194.1 - 6.1 7.4 12.1 12 6.5 12.1 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Methyltransf_11 PF08241.12 EJP62195.1 - 0.0084 16.7 0.0 0.013 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP62195.1 - 0.091 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PAPS_reduct PF01507.19 EJP62197.1 - 1e-40 139.6 0.0 1.4e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF5363 PF17320.2 EJP62197.1 - 0.1 12.5 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5363) TYW3 PF02676.14 EJP62199.1 - 1.4e-70 237.0 0.0 1.7e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1690 PF07956.11 EJP62200.1 - 8e-42 143.0 1.9 9.4e-42 142.7 1.9 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF3123 PF11321.8 EJP62200.1 - 0.047 14.4 0.4 0.092 13.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) GvpL_GvpF PF06386.11 EJP62200.1 - 9.3 6.1 9.7 38 4.1 9.7 2.0 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Ferric_reduct PF01794.19 EJP62201.1 - 1.1e-23 83.6 7.9 3.3e-23 82.2 7.9 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EJP62201.1 - 2.2e-19 70.1 0.0 1.6e-16 60.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EJP62201.1 - 7.7e-08 32.4 0.0 1.1e-06 28.7 0.0 2.5 2 1 0 2 2 2 1 FAD-binding domain TP_methylase PF00590.20 EJP62202.1 - 4.2e-43 147.8 1.3 1.2e-42 146.3 1.3 1.8 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EJP62202.1 - 2.4e-17 63.3 0.0 5.2e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EJP62202.1 - 8.7e-12 44.3 0.1 2e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 EJP62202.1 - 6.6e-10 38.5 0.5 1.9e-09 37.0 0.1 1.9 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Rsm22 PF09243.10 EJP62203.1 - 2.5e-29 102.4 0.0 3.1e-28 98.8 0.0 2.6 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Aa_trans PF01490.18 EJP62204.1 - 1.7e-82 277.3 14.7 2.4e-82 276.8 14.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.10 EJP62204.1 - 0.048 11.9 1.1 0.075 11.3 1.1 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SieB PF14163.6 EJP62204.1 - 0.2 11.2 0.6 0.71 9.4 0.6 2.0 1 0 0 1 1 1 0 Super-infection exclusion protein B Ribosomal_S16 PF00886.19 EJP62205.1 - 1.3e-24 86.0 0.1 1.8e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 EJP62206.1 - 1.1e-33 116.5 0.0 1.4e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 EJP62206.1 - 0.09 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein COesterase PF00135.28 EJP62207.1 - 6.9e-79 266.0 0.0 7.8e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EJP62207.1 - 7.6e-05 22.7 0.2 0.00026 20.9 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EJP62207.1 - 0.0043 16.6 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family AA_permease PF00324.21 EJP62208.1 - 1.2e-120 403.4 48.2 1.5e-120 403.1 48.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP62208.1 - 7.7e-31 107.4 50.6 1e-30 106.9 50.6 1.1 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 EJP62208.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Pet100 NCE101 PF11654.8 EJP62208.1 - 3.5 7.4 5.0 0.67 9.7 0.3 2.2 3 0 0 3 3 3 0 Non-classical export protein 1 SBP_bac_3 PF00497.20 EJP62209.1 - 0.01 15.3 1.0 0.011 15.2 1.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 LIAS_N PF16881.5 EJP62210.1 - 5.3e-20 71.9 0.0 1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EJP62210.1 - 4e-12 46.8 0.0 9.5e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Methyltrn_RNA_3 PF02598.17 EJP62211.1 - 7.4e-91 304.6 0.0 1.2e-89 300.6 0.0 2.3 2 1 0 2 2 2 1 Putative RNA methyltransferase SelP_N PF04592.14 EJP62211.1 - 0.6 9.5 12.3 0.93 8.9 12.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CAF20 PF17052.5 EJP62211.1 - 1.5 8.9 5.4 2.6 8.2 5.4 1.3 1 0 0 1 1 1 0 Cap associated factor NicO PF03824.16 EJP62211.1 - 7 5.9 7.1 11 5.3 7.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Thioredoxin PF00085.20 EJP62212.1 - 5.9e-18 64.7 0.4 1.5e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EJP62212.1 - 0.0077 16.7 0.1 0.022 15.2 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EJP62212.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 EJP62212.1 - 0.023 15.0 0.0 0.16 12.3 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 EJP62212.1 - 0.086 12.2 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Hyaluronidase_1 PF07212.11 EJP62212.1 - 0.19 11.0 0.2 0.29 10.4 0.2 1.2 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) SH3_1 PF00018.28 EJP62213.1 - 4.4e-09 35.8 0.1 9e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP62213.1 - 1.6e-06 27.9 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJP62213.1 - 1.3e-05 24.8 0.0 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DASH_Spc19 PF08287.11 EJP62214.1 - 3e-44 150.7 2.9 4.3e-44 150.2 2.9 1.2 1 0 0 1 1 1 1 Spc19 RecG_N PF17190.4 EJP62214.1 - 0.014 16.1 1.2 0.025 15.3 0.0 1.8 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF1120 PF06551.12 EJP62215.1 - 0.16 12.2 0.1 0.19 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) tRNA-synt_1b PF00579.25 EJP62216.1 - 4e-62 210.2 0.0 5.1e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PCI PF01399.27 EJP62217.1 - 1.5e-21 76.8 0.1 7.6e-21 74.6 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EJP62217.1 - 1.7e-16 60.0 2.9 4.7e-16 58.6 2.9 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain FSH1 PF03959.13 EJP62218.1 - 1.3e-60 204.7 0.0 1.6e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Ifi-6-16 PF06140.13 EJP62218.1 - 0.086 12.8 3.4 0.24 11.3 0.4 2.7 3 0 0 3 3 3 0 Interferon-induced 6-16 family PE-PPE PF08237.11 EJP62218.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain ATP-synt_J PF04911.12 EJP62219.1 - 9.7e-27 92.3 2.7 1.1e-26 92.2 2.7 1.0 1 0 0 1 1 1 1 ATP synthase j chain NIPSNAP PF07978.13 EJP62220.1 - 2.5e-42 143.3 0.4 1.9e-30 105.1 0.1 2.6 2 0 0 2 2 2 2 NIPSNAP Rogdi_lz PF10259.9 EJP62221.1 - 5.6e-91 304.7 0.0 6.4e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein PP2C PF00481.21 EJP62222.1 - 1.1e-42 146.4 0.0 1.7e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EJP62222.1 - 0.015 15.2 0.1 5.3 6.9 0.0 2.8 4 0 0 4 4 4 0 Stage II sporulation protein E (SpoIIE) DotU PF09850.9 EJP62222.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system protein DotU Tyrosinase PF00264.20 EJP62223.1 - 3.9e-21 76.4 0.4 6.9e-21 75.6 0.4 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Ribosomal_L27A PF00828.19 EJP62225.1 - 4.5e-32 111.4 0.1 7.3e-32 110.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glyco_transf_15 PF01793.16 EJP62226.1 - 6.9e-98 327.9 5.3 2.5e-97 326.0 5.3 1.7 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4604 PF15377.6 EJP62227.1 - 1.4e-33 116.8 15.7 1.6e-33 116.6 15.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) TAF4 PF05236.14 EJP62227.1 - 0.12 12.2 6.3 0.14 11.9 6.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PGA2 PF07543.12 EJP62227.1 - 0.99 9.4 10.9 1 9.3 10.0 1.4 2 0 0 2 2 2 0 Protein trafficking PGA2 COX5B PF01215.19 EJP62228.1 - 1.8e-57 192.6 0.1 2.7e-57 192.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 EJP62228.1 - 0.006 16.3 0.2 2 8.3 0.0 2.3 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger His_Phos_1 PF00300.22 EJP62230.1 - 3.1e-28 98.8 0.6 1.8e-27 96.3 0.6 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Formyl_trans_N PF00551.19 EJP62230.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase ERCC4 PF02732.15 EJP62231.1 - 2e-19 70.3 0.1 2e-19 70.3 0.1 2.1 1 1 1 2 2 2 1 ERCC4 domain CRT10 PF08728.10 EJP62231.1 - 0.63 8.1 2.5 0.89 7.7 2.5 1.1 1 0 0 1 1 1 0 CRT10 RR_TM4-6 PF06459.12 EJP62231.1 - 1.3 8.8 6.2 2.1 8.1 6.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med19 PF10278.9 EJP62231.1 - 3.1 7.7 10.6 5.6 6.9 10.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 NPR3 PF03666.13 EJP62231.1 - 4.4 6.0 8.9 6.8 5.4 8.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Kinesin PF00225.23 EJP62232.1 - 8.4e-93 310.9 2.6 1.6e-92 310.0 0.0 2.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EJP62232.1 - 7.7e-17 61.6 0.0 7.7e-14 51.9 0.0 3.4 2 0 0 2 2 2 2 Microtubule binding DNA_binding_1 PF01035.20 EJP62233.1 - 2.5e-24 85.2 0.1 3.1e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SLC12 PF03522.15 EJP62234.1 - 2.2 7.2 11.3 2 7.3 11.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Asp-B-Hydro_N PF05279.11 EJP62234.1 - 2.9 7.9 19.1 3.2 7.8 19.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TP53IP5 PF15331.6 EJP62234.1 - 5 7.2 15.8 5.7 7.0 15.8 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 RR_TM4-6 PF06459.12 EJP62234.1 - 6.1 6.6 19.2 6.7 6.4 19.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TipE PF16972.5 EJP62234.1 - 8.7 5.4 10.0 11 5.1 10.0 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Fungal_trans PF04082.18 EJP62235.1 - 1.2e-11 44.2 0.1 1.9e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chorion_3 PF05387.11 EJP62235.1 - 0.064 12.9 0.1 0.064 12.9 0.1 2.0 2 0 0 2 2 2 0 Chorion family 3 NACHT_N PF17100.5 EJP62236.1 - 9.4e-25 87.8 2.1 1.2e-24 87.4 1.1 1.7 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 EJP62236.1 - 5.1e-20 71.9 7.9 2.6e-10 40.7 0.1 5.4 4 2 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP62236.1 - 1.7e-15 55.6 11.1 0.0067 16.8 0.0 8.2 9 0 0 9 9 9 4 Ankyrin repeat Ank_4 PF13637.6 EJP62236.1 - 6.6e-15 55.3 7.4 1.8e-09 38.0 0.2 5.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EJP62236.1 - 8.2e-12 45.0 10.6 0.005 17.2 0.3 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EJP62236.1 - 1.6e-07 31.5 9.1 9.4e-06 25.8 0.3 5.1 5 1 1 6 6 6 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 EJP62236.1 - 4.1e-06 27.3 1.5 0.0003 21.2 0.0 3.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EJP62236.1 - 0.00039 20.7 0.1 0.0064 16.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EJP62236.1 - 0.012 16.0 0.0 0.11 12.9 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane PF01061.24 EJP62237.1 - 2.4e-86 288.5 58.6 8e-48 162.6 22.0 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EJP62237.1 - 8.1e-37 126.8 0.0 3.2e-18 66.5 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EJP62237.1 - 2.1e-35 120.5 11.4 4.1e-31 106.7 0.1 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EJP62237.1 - 2.2e-19 69.8 0.0 6.4e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 EJP62237.1 - 5.2e-06 26.7 0.1 0.014 15.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EJP62237.1 - 5.8e-06 26.3 0.1 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EJP62237.1 - 5.8e-06 26.8 0.2 0.045 14.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EJP62237.1 - 6.8e-06 25.8 0.1 0.00062 19.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EJP62237.1 - 4e-05 22.9 42.3 0.0069 15.5 16.7 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_18 PF13238.6 EJP62237.1 - 7.4e-05 23.3 0.0 0.034 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EJP62237.1 - 0.00035 20.3 0.6 0.048 13.4 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EJP62237.1 - 0.00038 20.4 0.3 0.58 9.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP62237.1 - 0.0017 17.8 0.0 0.72 9.2 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 EJP62237.1 - 0.0037 16.9 0.8 0.072 12.7 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EJP62237.1 - 0.0073 16.2 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EJP62237.1 - 0.0085 16.4 0.3 2 8.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EJP62237.1 - 0.0097 16.3 0.3 1.9 8.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 EJP62237.1 - 0.018 15.5 0.1 4.8 7.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EJP62237.1 - 0.022 14.7 0.4 4.8 7.1 0.2 2.8 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EJP62237.1 - 0.029 14.1 0.3 2.4 7.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EJP62237.1 - 0.056 13.2 0.7 8.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EJP62237.1 - 0.22 11.7 0.4 2.9 8.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain NAD_binding_8 PF13450.6 EJP62238.1 - 3.4e-11 43.2 0.1 6.7e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP62238.1 - 9.5e-09 34.8 0.5 1.5e-08 34.2 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EJP62238.1 - 5.5e-08 32.5 0.0 2.8e-07 30.2 0.0 2.1 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EJP62238.1 - 8.9e-08 31.9 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP62238.1 - 2.1e-07 30.0 0.3 3.2e-07 29.4 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EJP62238.1 - 3.3e-05 23.7 0.4 5.6e-05 22.9 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP62238.1 - 6.5e-05 23.4 0.1 0.00013 22.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP62238.1 - 8.8e-05 21.9 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP62238.1 - 0.00024 20.4 0.1 0.00037 19.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EJP62238.1 - 0.00051 19.4 0.2 0.00084 18.7 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP62238.1 - 0.0097 15.0 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 EJP62238.1 - 0.018 14.3 0.2 0.031 13.5 0.2 1.3 1 0 0 1 1 1 0 Thi4 family IlvN PF07991.12 EJP62238.1 - 0.019 14.6 0.2 0.05 13.2 0.2 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 EJP62238.1 - 0.066 12.9 0.3 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 EJP62238.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EJP62238.1 - 0.14 11.4 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EJP62238.1 - 0.15 12.5 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3425 PF11905.8 EJP62239.1 - 3.6e-25 88.3 0.0 5.7e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EJP62239.1 - 0.00014 21.9 4.9 0.00022 21.2 4.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EJP62239.1 - 0.0091 16.1 6.6 0.015 15.4 6.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper CRAL_TRIO PF00650.20 EJP62240.1 - 1.7e-33 115.6 0.1 2.5e-33 115.0 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJP62240.1 - 5.9e-14 52.0 0.1 1.2e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EJP62240.1 - 0.025 14.7 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain polyprenyl_synt PF00348.17 EJP62241.1 - 8.5e-50 169.2 0.2 8.5e-50 169.2 0.2 2.2 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 EJP62241.1 - 1.4e-09 37.7 0.3 7.3e-07 28.8 0.1 2.3 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain SRA1 PF07304.11 EJP62241.1 - 0.073 12.9 1.2 2 8.2 0.1 2.6 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) DUF5530 PF17670.1 EJP62241.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5530) Pirin PF02678.16 EJP62241.1 - 0.16 11.9 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 Pirin p450 PF00067.22 EJP62242.1 - 5.8e-53 180.3 0.0 7.6e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 EJP62243.1 - 5.4e-09 36.0 15.1 5.4e-09 36.0 15.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.15 EJP62244.1 - 4.3e-26 91.5 0.9 7.7e-12 44.6 0.0 4.1 3 1 0 3 3 3 3 Transferase family ABC_tran PF00005.27 EJP62245.1 - 7.7e-28 97.7 0.1 1.3e-27 97.0 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EJP62245.1 - 3.6e-24 85.3 26.0 3.6e-24 85.3 26.0 1.5 2 0 0 2 2 1 1 ABC-2 type transporter SMC_N PF02463.19 EJP62245.1 - 2.9e-06 26.9 0.0 1.4e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EJP62245.1 - 1.7e-05 25.3 0.0 3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EJP62245.1 - 6.4e-05 22.9 0.3 0.12 12.2 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EJP62245.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EJP62245.1 - 0.00045 20.0 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EJP62245.1 - 0.00051 20.3 0.0 0.001 19.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EJP62245.1 - 0.00064 19.4 0.2 0.0013 18.5 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP62245.1 - 0.0015 18.5 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_13 PF13166.6 EJP62245.1 - 0.003 16.3 0.1 0.025 13.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EJP62245.1 - 0.0039 17.7 0.0 0.0066 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EJP62245.1 - 0.0041 16.2 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EJP62245.1 - 0.0075 16.0 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EJP62245.1 - 0.0076 16.2 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 EJP62245.1 - 0.0093 16.2 0.3 0.017 15.4 0.3 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EJP62245.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EJP62245.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EJP62245.1 - 0.033 14.6 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EJP62245.1 - 0.037 14.4 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 EJP62245.1 - 0.038 13.6 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EJP62245.1 - 0.052 13.4 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 EJP62245.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 EJP62245.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EJP62245.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EJP62245.1 - 0.098 12.7 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EJP62245.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 EJP62245.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 EJP62245.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 EJP62245.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EJP62245.1 - 0.16 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 EJP62245.1 - 0.16 12.3 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 EJP62245.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Cytidylate_kin PF02224.18 EJP62245.1 - 0.19 11.4 0.2 0.33 10.7 0.2 1.3 1 0 0 1 1 1 0 Cytidylate kinase Dynamin_N PF00350.23 EJP62245.1 - 0.21 11.7 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Dynamin family ATPase_2 PF01637.18 EJP62245.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sugar_tr PF00083.24 EJP62246.1 - 4.1e-91 306.1 28.3 4.9e-91 305.9 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP62246.1 - 9.4e-23 80.7 63.7 5.9e-20 71.5 35.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 EJP62246.1 - 0.097 13.2 0.6 0.52 10.9 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HAD PF12710.7 EJP62247.1 - 0.00089 19.7 0.0 0.0028 18.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N_2 PF13602.6 EJP62248.1 - 2.6e-23 83.5 0.0 4.9e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EJP62248.1 - 2.5e-13 50.1 0.2 4.4e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP62248.1 - 1.5e-08 34.5 0.9 6.1e-07 29.3 0.0 2.6 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pro-kuma_activ PF09286.11 EJP62249.1 - 1.9e-30 106.0 0.0 3.7e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP62249.1 - 0.00016 21.0 0.1 0.00033 20.0 0.1 1.5 1 0 0 1 1 1 1 Subtilase family GOLGA2L5 PF15070.6 EJP62249.1 - 0.076 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Solute_trans_a PF03619.16 EJP62250.1 - 2.4e-59 201.0 14.2 3.4e-59 200.5 14.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Claudin_3 PF06653.11 EJP62250.1 - 0.19 11.6 6.6 0.2 11.6 4.2 2.2 2 1 0 2 2 2 0 Tight junction protein, Claudin-like HsbA PF12296.8 EJP62251.1 - 1.8e-19 70.3 4.5 2.6e-19 69.8 4.5 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A HsbA PF12296.8 EJP62252.1 - 1.3e-13 51.4 5.5 1.3e-13 51.4 5.5 3.0 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Metallophos PF00149.28 EJP62253.1 - 4.2e-12 47.0 0.3 6e-12 46.5 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_92 PF07971.12 EJP62254.1 - 1.1e-147 492.8 0.0 1.3e-147 492.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EJP62254.1 - 9.1e-60 202.5 1.5 1.4e-59 201.9 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF4241 PF14025.6 EJP62254.1 - 0.095 13.0 0.1 7.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) NTP_transf_2 PF01909.23 EJP62255.1 - 7.3e-05 23.0 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EJP62255.1 - 9.3e-05 22.4 0.0 0.00031 20.8 0.0 1.9 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase MIP PF00230.20 EJP62256.1 - 3.9e-33 115.1 5.9 5.5e-33 114.6 5.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein XK-related PF09815.9 EJP62256.1 - 0.42 9.6 4.8 0.12 11.4 0.7 2.0 2 0 0 2 2 2 0 XK-related protein HNH_2 PF13391.6 EJP62257.1 - 1.4e-12 47.5 0.1 3.4e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease HEAT_2 PF13646.6 EJP62258.1 - 5e-26 90.9 43.7 1e-10 41.9 4.2 5.6 2 2 2 4 4 4 4 HEAT repeats NACHT PF05729.12 EJP62258.1 - 2.3e-18 66.7 0.3 1.5e-17 64.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain HEAT_EZ PF13513.6 EJP62258.1 - 1.5e-12 47.7 33.0 5.6e-06 26.7 2.3 6.5 4 3 4 8 8 8 4 HEAT-like repeat HEAT PF02985.22 EJP62258.1 - 4e-11 42.2 24.6 0.013 15.7 0.1 8.4 8 0 0 8 8 8 4 HEAT repeat NLRC4_HD2 PF17776.1 EJP62258.1 - 4.6e-06 27.2 0.2 1.9e-05 25.2 0.0 2.1 2 1 0 2 2 1 1 NLRC4 helical domain HD2 NB-ARC PF00931.22 EJP62258.1 - 4.3e-05 22.8 0.0 9.5e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EJP62258.1 - 0.00022 21.7 0.0 0.00022 21.7 0.0 2.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP62258.1 - 0.00064 20.0 0.0 0.0039 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF5494 PF17598.2 EJP62258.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5494) AAA_18 PF13238.6 EJP62258.1 - 0.04 14.5 0.0 0.15 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EJP62258.1 - 0.04 13.8 0.2 0.082 12.8 0.2 1.5 1 0 0 1 1 1 0 NTPase Vac14_Fab1_bd PF12755.7 EJP62258.1 - 0.067 13.8 0.5 9.5 6.9 0.0 4.2 3 2 3 6 6 6 0 Vacuolar 14 Fab1-binding region AAA PF00004.29 EJP62258.1 - 0.077 13.4 0.0 0.29 11.6 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EJP62258.1 - 0.15 12.5 0.0 0.74 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase RICTOR_N PF14664.6 EJP62258.1 - 0.24 10.4 1.4 23 3.8 0.0 3.4 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_PBS PF03130.16 EJP62258.1 - 0.96 10.3 30.0 10 7.1 0.5 7.0 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat Cellulase PF00150.18 EJP62259.1 - 2e-17 63.5 2.8 3.6e-17 62.7 2.8 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_12 PF13424.6 EJP62260.1 - 6.3e-13 48.8 11.7 1.4e-07 31.7 1.1 4.8 3 1 2 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.22 EJP62260.1 - 4.3e-09 35.9 0.0 1.7e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 EJP62260.1 - 1.8e-08 34.0 13.9 0.0029 17.4 0.1 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat AAA_22 PF13401.6 EJP62260.1 - 0.00013 22.2 0.0 0.0004 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP62260.1 - 0.001 19.5 0.8 0.0038 17.6 0.8 2.1 1 1 0 1 1 1 1 AAA ATPase domain TPR_2 PF07719.17 EJP62260.1 - 0.0059 16.6 7.2 17 5.8 0.4 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 EJP62260.1 - 0.082 13.6 5.3 7.7 7.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EJP62260.1 - 0.32 10.9 4.4 6.7 6.7 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HAD_2 PF13419.6 EJP62261.1 - 2.7e-18 66.7 0.0 4.5e-18 65.9 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP62261.1 - 2.4e-08 34.5 0.0 0.00028 21.3 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP62261.1 - 3.7e-05 23.7 0.0 7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4444 PF14563.6 EJP62261.1 - 0.35 10.6 1.3 8.8 6.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) CMS1 PF14617.6 EJP62263.1 - 1.5e-76 257.1 3.5 1.6e-76 257.0 3.5 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EJP62263.1 - 4.6e-07 29.8 0.0 6.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.22 EJP62265.1 - 2.7e-08 33.5 0.3 9.2e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 EJP62266.1 - 2.9e-47 160.3 0.0 3.6e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP62266.1 - 5.1e-15 55.8 0.0 7.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP62266.1 - 0.0032 16.9 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Peptidase_S10 PF00450.22 EJP62267.1 - 1.6e-120 403.3 0.2 2.2e-120 402.9 0.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase FPN1 PF06963.12 EJP62267.1 - 1.3e-114 383.1 13.3 2.1e-114 382.5 13.3 1.3 1 0 0 1 1 1 1 Ferroportin1 (FPN1) CENP-T_C PF15511.6 EJP62268.1 - 8.9e-41 138.4 0.0 4.2e-40 136.2 0.0 2.1 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EJP62268.1 - 1.3e-07 31.9 0.2 2.4e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EJP62268.1 - 2.4e-05 24.7 0.1 2.4e-05 24.7 0.1 2.4 2 2 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SURF1 PF02104.15 EJP62269.1 - 1.1e-46 159.3 0.0 1.7e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 SURF1 family LIP PF03583.14 EJP62270.1 - 3e-61 207.3 0.0 4.2e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_2 PF02230.16 EJP62270.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EJP62270.1 - 0.17 11.3 0.1 0.69 9.3 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family UBX PF00789.20 EJP62272.1 - 1.7e-15 56.9 0.0 3.2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain Atg14 PF10186.9 EJP62272.1 - 0.79 8.7 10.8 1.1 8.3 10.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 WDCP PF15390.6 EJP62272.1 - 6.3 5.0 5.5 8.5 4.6 5.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF2076 PF09849.9 EJP62273.1 - 9.3e-09 35.7 15.2 1.3e-08 35.2 15.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EJP62273.1 - 1.5e-05 25.0 2.1 1.5e-05 25.0 2.1 1.7 1 1 1 2 2 2 1 CHCH domain Trypan_glycop_C PF10659.9 EJP62273.1 - 0.0034 17.7 2.5 0.0057 17.0 2.5 1.3 1 0 0 1 1 1 1 Trypanosome variant surface glycoprotein C-terminal domain COX6B PF02297.17 EJP62273.1 - 0.018 15.3 2.3 0.028 14.7 2.3 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb GCK PF07802.11 EJP62273.1 - 0.083 13.3 0.2 0.12 12.8 0.2 1.3 1 0 0 1 1 1 0 GCK domain Pex14_N PF04695.13 EJP62273.1 - 2.9 8.6 15.6 4.9 7.8 8.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CX9C PF16860.5 EJP62273.1 - 3.5 7.7 9.2 0.68 10.0 2.5 2.2 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TFIIA PF03153.13 EJP62273.1 - 5.7 6.8 9.4 7.4 6.5 9.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sas10_Utp3 PF04000.15 EJP62274.1 - 2.1e-14 53.9 0.6 2.1e-14 53.9 0.6 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family BLOC1_2 PF10046.9 EJP62274.1 - 0.0019 18.5 0.5 0.28 11.5 0.1 2.5 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 EJP62274.1 - 0.028 14.8 0.8 0.17 12.3 0.1 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 EJP62274.1 - 0.033 14.6 1.1 0.24 11.9 1.1 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein XRN_M PF17846.1 EJP62274.1 - 0.12 11.3 0.7 0.13 11.2 0.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain UPF0184 PF03670.13 EJP62274.1 - 0.44 11.0 2.5 0.6 10.5 0.6 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) ApbA_C PF08546.11 EJP62275.1 - 4e-21 75.5 0.0 7.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EJP62275.1 - 7.9e-07 28.8 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Beta-lactamase PF00144.24 EJP62276.1 - 1.1e-23 84.0 0.2 1.9e-23 83.2 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase dsDNA_bind PF01984.20 EJP62277.1 - 2.5e-41 140.4 13.0 2.9e-41 140.2 13.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain K_channel_TID PF07941.11 EJP62277.1 - 0.065 13.7 6.8 0.14 12.6 6.8 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Tom5 PF10642.9 EJP62277.1 - 0.22 11.6 1.2 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Orbi_VP5 PF00901.17 EJP62277.1 - 0.37 9.1 3.2 0.46 8.8 3.2 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF5401 PF17380.2 EJP62277.1 - 0.7 7.9 9.6 0.77 7.8 9.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) LCIB_C_CA PF18599.1 EJP62277.1 - 1.3 8.3 4.0 2.7 7.3 4.0 1.5 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Coq4 PF05019.13 EJP62278.1 - 2.3e-95 318.1 0.0 2.7e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 zf-TFIIB PF13453.6 EJP62278.1 - 0.073 12.4 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger SET PF00856.28 EJP62279.1 - 4.2e-08 33.8 0.0 7.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 SET domain Pro-kuma_activ PF09286.11 EJP62279.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain RRM_1 PF00076.22 EJP62280.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EJP62281.1 - 5.9e-17 61.7 14.2 4.4e-05 24.1 0.3 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP62281.1 - 2.2e-05 24.6 0.0 0.0092 16.3 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain YL1 PF05764.13 EJP62281.1 - 0.00097 19.3 10.1 0.0017 18.5 10.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Cytochrom_D1 PF02239.16 EJP62281.1 - 0.002 16.8 3.0 0.072 11.6 0.1 3.3 4 0 0 4 4 4 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 EJP62281.1 - 0.051 14.1 0.6 2.7 8.6 0.0 3.1 4 0 0 4 4 4 0 PQQ-like domain WD40_like PF17005.5 EJP62281.1 - 0.09 12.1 0.0 1.5 8.1 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain SDA1 PF05285.12 EJP62281.1 - 0.26 10.7 18.0 0.41 10.0 18.0 1.2 1 0 0 1 1 1 0 SDA1 PD40 PF07676.12 EJP62281.1 - 0.28 11.2 0.1 0.28 11.2 0.1 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat FRQ PF09421.10 EJP62281.1 - 2.2 6.2 11.6 3.3 5.6 11.6 1.1 1 0 0 1 1 1 0 Frequency clock protein BUD22 PF09073.10 EJP62281.1 - 6.7 5.9 16.2 11 5.3 16.2 1.3 1 0 0 1 1 1 0 BUD22 UPF0016 PF01169.19 EJP62282.1 - 3.1e-40 136.4 25.4 2.5e-20 72.6 8.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TackOD1 PF18551.1 EJP62283.1 - 0.023 14.4 0.4 0.034 13.8 0.4 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Neocarzinostat PF00960.18 EJP62283.1 - 0.056 13.4 0.4 0.11 12.5 0.2 1.6 1 1 0 1 1 1 0 Neocarzinostatin family DZR PF12773.7 EJP62283.1 - 0.086 12.9 1.9 0.21 11.7 1.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 EJP62283.1 - 0.27 10.9 1.9 0.29 10.8 0.6 1.7 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DUF1115 PF06544.12 EJP62284.1 - 1.5e-12 47.8 0.0 2.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) NACHT PF05729.12 EJP62285.1 - 1.3e-07 31.7 0.0 4e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EJP62285.1 - 1.3e-05 25.7 0.1 6.2e-05 23.4 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP62285.1 - 0.00015 22.1 0.0 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EJP62285.1 - 0.00048 20.5 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.14 EJP62285.1 - 0.0009 18.8 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EJP62285.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein AAA_24 PF13479.6 EJP62285.1 - 0.022 14.5 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.7 EJP62285.1 - 0.023 15.3 0.0 0.053 14.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_30 PF13604.6 EJP62285.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EJP62285.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 EJP62285.1 - 0.037 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Thioesterase PF00975.20 EJP62285.1 - 0.037 14.1 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain AAA PF00004.29 EJP62285.1 - 0.043 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MIB_HERC2 PF06701.13 EJP62285.1 - 0.045 14.0 0.2 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 Mib_herc2 RNA_helicase PF00910.22 EJP62285.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EJP62285.1 - 0.079 12.9 0.0 0.41 10.5 0.0 2.0 1 1 0 1 1 1 0 RsgA GTPase LIDHydrolase PF10230.9 EJP62285.1 - 0.079 12.5 0.1 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Cutinase PF01083.22 EJP62285.1 - 0.092 12.7 0.0 0.63 10.0 0.0 2.1 1 1 0 1 1 1 0 Cutinase Hydrolase_4 PF12146.8 EJP62285.1 - 0.095 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MMR_HSR1 PF01926.23 EJP62285.1 - 0.099 12.7 0.0 0.5 10.5 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EJP62285.1 - 0.12 12.8 0.0 0.44 11.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF900 PF05990.12 EJP62285.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Fungal_KA1 PF16797.5 EJP62285.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Fungal kinase associated-1 domain DUF1752 PF08550.10 EJP62286.1 - 2.7e-05 23.9 1.9 5e-05 23.0 1.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Lactamase_B PF00753.27 EJP62288.1 - 8.4e-18 65.1 6.4 1.5e-15 57.7 6.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EJP62288.1 - 3.5e-15 55.7 0.0 7.4e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EJP62288.1 - 3e-08 33.4 0.7 1.2e-07 31.5 0.2 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EJP62288.1 - 0.0016 18.4 0.2 0.0025 17.7 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EJP62288.1 - 0.086 12.3 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain Ank_2 PF12796.7 EJP62289.1 - 1.1e-27 96.4 0.2 2.7e-16 59.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP62289.1 - 4.1e-15 55.9 0.2 8.7e-08 32.6 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP62289.1 - 1.2e-12 47.8 0.0 1e-06 28.9 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EJP62289.1 - 9.3e-11 41.7 0.2 0.017 15.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EJP62289.1 - 1.6e-10 40.3 0.0 0.12 12.9 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat AAA_16 PF13191.6 EJP62289.1 - 2e-05 25.0 0.9 4.7e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EJP62289.1 - 9.7e-05 22.3 0.6 0.00021 21.2 0.1 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EJP62289.1 - 0.013 15.8 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJP62289.1 - 0.017 14.9 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EJP62289.1 - 0.074 13.5 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EJP62289.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EJP62289.1 - 1.2 9.7 3.7 6.7 7.3 0.6 3.0 2 1 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 EJP62290.1 - 0.0053 17.1 2.5 0.01 16.2 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP62290.1 - 0.039 14.8 2.4 0.086 13.7 2.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 EJP62290.1 - 0.13 12.7 1.9 0.24 11.9 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ank_2 PF12796.7 EJP62291.1 - 1.3e-16 60.9 0.0 2.7e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP62291.1 - 4.2e-14 52.4 0.2 4.9e-10 39.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP62291.1 - 2.2e-10 39.9 0.2 9e-05 22.6 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EJP62291.1 - 5.6e-10 39.2 1.2 0.00075 19.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EJP62291.1 - 1.3e-08 35.2 0.0 1.6e-07 31.8 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) PAD PF03068.15 EJP62292.1 - 1.2e-91 307.7 0.0 1.8e-91 307.0 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) 4HBT_2 PF13279.6 EJP62293.1 - 6.7e-06 26.6 0.0 1.1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DHDPS PF00701.22 EJP62294.1 - 4.7e-06 25.5 0.0 6.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Arf PF00025.21 EJP62295.1 - 1.5e-24 86.4 0.0 2.5e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GHMP_kinases_N PF00288.26 EJP62295.1 - 4.6e-09 36.4 1.2 4.4e-08 33.2 0.1 2.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain G-alpha PF00503.20 EJP62295.1 - 1.5e-05 24.4 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit GHMP_kinases_C PF08544.13 EJP62295.1 - 0.00069 19.9 0.0 0.0029 18.0 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal Roc PF08477.13 EJP62295.1 - 0.0027 17.9 0.0 0.0071 16.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Lipase_GDSL_2 PF13472.6 EJP62295.1 - 0.018 15.5 0.1 0.051 14.0 0.1 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Ras PF00071.22 EJP62295.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Ras family Gtr1_RagA PF04670.12 EJP62295.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Cerato-platanin PF07249.12 EJP62296.1 - 2.5e-51 172.8 0.6 3e-51 172.5 0.6 1.0 1 0 0 1 1 1 1 Cerato-platanin LtrA PF06772.11 EJP62298.1 - 9.8e-39 133.6 30.5 1.2e-38 133.2 30.5 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) CFEM PF05730.11 EJP62299.1 - 1.1e-11 44.6 9.8 1.9e-11 43.9 9.8 1.4 1 0 0 1 1 1 1 CFEM domain Zn_clus PF00172.18 EJP62300.1 - 9e-09 35.3 9.1 1.8e-08 34.3 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHM7_cyt PF14703.6 EJP62300.1 - 0.025 14.8 0.3 0.053 13.8 0.3 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter KIX_2 PF16987.5 EJP62300.1 - 0.056 13.4 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 KIX domain Sugar_tr PF00083.24 EJP62301.1 - 2.9e-87 293.4 19.6 3.4e-87 293.2 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP62301.1 - 2.8e-18 66.0 38.9 4.8e-11 42.2 17.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EJP62301.1 - 0.29 9.4 4.4 0.16 10.3 0.8 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PSDC PF12588.8 EJP62302.1 - 6.1e-59 198.0 0.0 8.9e-59 197.5 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EJP62302.1 - 8.8e-38 129.9 0.0 4e-37 127.7 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EJP62302.1 - 0.11 12.4 0.5 13 5.7 0.2 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like DUF2722 PF10846.8 EJP62303.1 - 1.8e-06 27.2 0.0 1.8e-06 27.2 0.0 3.0 1 1 0 2 2 2 1 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.18 EJP62304.1 - 3.6e-34 118.3 0.0 5.3e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DIL PF01843.19 EJP62305.1 - 1.3e-30 105.7 1.7 2.5e-30 104.8 1.7 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 EJP62305.1 - 4.5e-14 52.8 0.1 4.8e-13 49.5 0.1 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP62305.1 - 2.3e-09 37.6 0.4 4.1e-07 30.4 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EJP62305.1 - 4.2e-09 36.4 0.1 0.0066 16.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EJP62305.1 - 7.5e-08 32.5 0.0 4.5e-06 26.8 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP62305.1 - 4.1e-07 29.8 0.0 0.063 13.8 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat DUF2336 PF10098.9 EJP62305.1 - 0.28 10.6 3.5 3.1 7.2 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) Allantoicase PF03561.15 EJP62306.1 - 2.5e-93 309.7 0.2 1.9e-46 157.6 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.25 EJP62306.1 - 0.0015 18.6 0.8 0.06 13.5 0.0 2.5 2 1 0 2 2 2 1 F5/8 type C domain CN_hydrolase PF00795.22 EJP62307.1 - 5.3e-45 153.8 0.0 6.5e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.25 EJP62308.1 - 1.1e-38 133.1 0.0 1.8e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62308.1 - 7.1e-20 71.4 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EJP62308.1 - 0.00022 21.5 0.1 0.00047 20.5 0.1 1.5 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EJP62308.1 - 0.0014 17.5 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EJP62308.1 - 0.0072 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EJP62308.1 - 0.026 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EJP62308.1 - 0.065 13.2 0.2 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP62308.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Cytochrom_B561 PF03188.16 EJP62309.1 - 8.6e-13 48.6 6.7 1.4e-12 47.9 6.7 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 SPC12 PF06645.13 EJP62309.1 - 0.2 11.7 7.0 2.5 8.3 0.1 3.1 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) HATPase_c PF02518.26 EJP62310.1 - 3.3e-26 92.0 0.4 6.3e-26 91.1 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EJP62310.1 - 9.1e-21 74.1 0.1 2.5e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 EJP62310.1 - 2.5e-20 72.5 1.8 2.1e-10 40.7 0.5 3.7 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 EJP62310.1 - 1.1e-19 70.2 0.1 2.4e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EJP62310.1 - 3.4e-09 36.9 0.0 0.0012 19.0 0.0 3.4 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EJP62310.1 - 2.5e-08 34.1 1.2 0.00013 22.2 0.0 3.4 4 0 0 4 4 4 2 PAS fold PAS PF00989.25 EJP62310.1 - 5.3e-07 29.6 0.0 0.022 14.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EJP62310.1 - 0.0016 18.4 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 PAS domain His_Phos_1 PF00300.22 EJP62311.1 - 1.6e-26 93.2 0.0 3.9e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EJP62311.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) OMP_b-brl PF13505.6 EJP62311.1 - 0.93 9.6 4.5 1.9 8.6 4.5 1.5 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain SelP_N PF04592.14 EJP62311.1 - 3.1 7.1 15.4 7.3 5.9 15.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PRIMA1 PF16101.5 EJP62311.1 - 5.8 7.0 5.6 14 5.7 5.6 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1168 PF06658.12 EJP62312.1 - 5.3e-34 117.0 19.1 5.3e-34 117.0 19.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1168) DUF966 PF06136.13 EJP62312.1 - 0.053 13.2 5.9 0.063 13.0 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) VIR_N PF15912.5 EJP62312.1 - 0.96 9.0 6.0 1.4 8.5 6.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CDC45 PF02724.14 EJP62312.1 - 1.4 7.1 5.6 1.6 6.9 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EJP62312.1 - 1.6 7.4 4.5 1.6 7.4 4.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4603 PF15376.6 EJP62312.1 - 3 5.1 11.9 3.4 4.9 11.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Cpn60_TCP1 PF00118.24 EJP62313.1 - 9.1e-175 582.0 1.4 1e-174 581.8 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ecl1 PF12855.7 EJP62315.1 - 8e-18 66.2 16.2 1.1e-17 65.8 16.2 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 EJP62315.1 - 0.044 13.8 0.8 0.085 12.8 0.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PLATZ PF04640.14 EJP62315.1 - 0.83 10.3 4.9 0.23 12.1 1.2 2.0 2 1 0 2 2 2 0 PLATZ transcription factor DAO PF01266.24 EJP62316.1 - 2.4e-38 132.6 0.0 2.9e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP62316.1 - 2.7e-06 27.5 0.1 6.1e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP62316.1 - 0.0013 18.1 0.0 0.053 12.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP62316.1 - 0.0015 18.5 0.0 0.049 13.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EJP62316.1 - 0.0018 17.6 0.0 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EJP62316.1 - 0.0096 16.2 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain Glu_dehyd_C PF16912.5 EJP62316.1 - 0.016 14.7 0.0 0.14 11.6 0.0 2.4 2 1 1 3 3 3 0 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 EJP62316.1 - 0.019 14.0 0.0 0.088 11.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 EJP62316.1 - 0.028 14.5 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EJP62316.1 - 0.032 13.5 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EJP62316.1 - 0.043 14.4 0.0 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EJP62316.1 - 0.046 13.4 0.0 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 EJP62316.1 - 0.15 11.1 0.0 7.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.21 EJP62316.1 - 0.16 11.3 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 ThiF family AA_kinase PF00696.28 EJP62317.1 - 1.1e-28 100.5 0.2 2.1e-28 99.6 0.2 1.4 1 1 0 1 1 1 1 Amino acid kinase family Cys_Met_Meta_PP PF01053.20 EJP62318.1 - 2.4e-22 79.0 0.0 3.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EJP62318.1 - 0.00055 19.2 0.0 0.00087 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GST_N PF02798.20 EJP62319.1 - 3e-10 40.3 0.1 3.1e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EJP62319.1 - 1.5e-05 25.1 0.1 9.3e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EJP62319.1 - 2.1e-05 24.9 0.0 4.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EJP62319.1 - 2.1e-05 24.7 0.0 5.4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EJP62319.1 - 3.4e-05 23.8 0.1 6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pyr_redox_2 PF07992.14 EJP62320.1 - 1.3e-59 201.8 1.1 1.8e-59 201.4 1.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EJP62320.1 - 1.1e-32 112.5 0.4 3.3e-32 111.0 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EJP62320.1 - 3.8e-21 75.4 0.3 6.5e-20 71.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP62320.1 - 1.7e-14 53.8 0.2 2.6e-14 53.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP62320.1 - 1.6e-05 24.2 0.1 0.00058 19.1 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EJP62320.1 - 0.0017 17.7 0.1 0.0036 16.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 EJP62320.1 - 0.003 16.9 0.5 1.7 7.9 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EJP62320.1 - 0.023 14.6 0.5 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EJP62320.1 - 0.023 13.4 3.3 2.1 7.0 0.0 3.0 2 1 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 EJP62320.1 - 0.052 12.4 0.0 0.33 9.8 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase 2-Hacid_dh_C PF02826.19 EJP62320.1 - 0.081 12.3 0.3 0.92 8.8 0.0 2.7 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EJP62320.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase EF-hand_4 PF12763.7 EJP62321.1 - 3.4e-32 110.5 0.0 2e-13 50.2 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EJP62321.1 - 6.7e-10 39.3 0.0 1.5e-05 25.4 0.0 4.3 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EJP62321.1 - 3.7e-09 35.5 0.0 0.25 11.0 0.0 5.5 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EJP62321.1 - 3.3e-06 26.6 0.0 10 6.3 0.0 5.4 5 0 0 5 5 5 0 EF-hand domain EF-hand_8 PF13833.6 EJP62321.1 - 0.0013 18.6 0.0 26 4.8 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain pair CENP-F_leu_zip PF10473.9 EJP62321.1 - 0.0066 16.5 9.4 0.0066 16.5 9.4 2.3 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UBA PF00627.31 EJP62321.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain FUSC PF04632.12 EJP62321.1 - 0.35 9.4 10.6 0.54 8.7 10.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pannexin_like PF12534.8 EJP62321.1 - 0.43 9.6 6.6 1 8.4 6.6 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 FliJ PF02050.16 EJP62321.1 - 0.46 10.7 29.8 1.4 9.1 13.0 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein APG6_N PF17675.1 EJP62321.1 - 0.55 10.8 31.5 1.2 9.6 17.9 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Csm1_N PF18504.1 EJP62321.1 - 1.2 9.5 23.1 0.041 14.2 2.5 3.5 3 0 0 3 3 3 0 Csm1 N-terminal domain Occludin_ELL PF07303.13 EJP62321.1 - 1.8 9.4 13.0 3.3 8.5 2.7 2.5 1 1 1 2 2 2 0 Occludin homology domain Lebercilin PF15619.6 EJP62321.1 - 2.1 7.9 29.9 0.5 10.0 24.1 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 EJP62321.1 - 2.6 7.3 30.6 2.3 7.5 16.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SOGA PF11365.8 EJP62321.1 - 3.3 8.9 18.2 11 7.2 2.7 2.8 1 1 0 2 2 2 0 Protein SOGA Spc7 PF08317.11 EJP62321.1 - 5.8 5.7 29.3 1.8 7.4 7.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 EJP62321.1 - 6.2 7.2 27.0 1.2 9.5 15.9 2.3 1 1 1 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 EJP62321.1 - 7.4 6.8 23.7 0.5 10.6 4.6 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Tup_N PF08581.10 EJP62321.1 - 8.6 6.8 16.6 15 6.0 7.0 2.4 2 0 0 2 2 2 0 Tup N-terminal Sec6 PF06046.13 EJP62322.1 - 4.8e-162 540.3 0.5 6.1e-162 540.0 0.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 EJP62322.1 - 0.00015 20.9 0.0 0.0051 15.8 0.0 3.0 3 1 1 4 4 4 1 Vps53-like, N-terminal zf-HIT PF04438.16 EJP62323.1 - 2e-09 37.2 9.0 3e-09 36.6 9.0 1.3 1 0 0 1 1 1 1 HIT zinc finger DENN PF02141.21 EJP62324.1 - 3.4e-40 138.0 0.0 5.8e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EJP62324.1 - 2.7e-08 34.4 0.1 1.4e-07 32.2 0.0 2.3 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 EJP62324.1 - 1.3 9.6 15.1 0.025 15.1 6.6 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2570 PF10828.8 EJP62324.1 - 3.9 7.3 14.6 1.3 8.9 8.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) CENP-F_leu_zip PF10473.9 EJP62324.1 - 7.7 6.5 26.1 0.35 10.9 6.7 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 EJP62324.1 - 8.6 6.5 22.2 0.91 9.6 9.8 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase LysM PF01476.20 EJP62326.1 - 2.8e-06 27.3 0.0 0.00058 19.9 0.0 2.2 2 0 0 2 2 2 2 LysM domain Phosphodiest PF01663.22 EJP62327.1 - 3.3e-32 112.5 0.0 9.7e-32 110.9 0.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Zn_clus PF00172.18 EJP62328.1 - 2.1e-09 37.3 9.6 3.7e-09 36.6 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP62328.1 - 2.1e-05 23.7 1.7 3.7e-05 22.9 0.1 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain PAD_porph PF04371.15 EJP62329.1 - 1.2e-97 327.1 0.0 1.4e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase FAD_binding_4 PF01565.23 EJP62330.1 - 3.1e-11 43.2 0.2 4e-11 42.8 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP62331.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Perilipin PF03036.16 EJP62332.1 - 0.00017 20.8 0.2 0.00021 20.4 0.2 1.3 1 0 0 1 1 1 1 Perilipin family OsmC PF02566.19 EJP62333.1 - 1e-14 54.8 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein SET PF00856.28 EJP62334.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.6 2 0 0 2 2 2 0 SET domain Lipase_3 PF01764.25 EJP62335.1 - 6.3e-07 29.4 0.0 1.6e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 EJP62335.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP62335.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 EJP62335.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Acyltransferase PF01553.21 EJP62336.1 - 0.009 15.6 0.0 0.03 13.9 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase Trypsin PF00089.26 EJP62339.1 - 9.2e-26 91.0 0.3 1.4e-25 90.4 0.3 1.3 1 0 0 1 1 1 1 Trypsin NAD_binding_6 PF08030.12 EJP62345.1 - 7.9e-09 35.8 0.0 1e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EJP62345.1 - 0.08 13.6 0.0 0.11 13.2 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Tubulin_C PF03953.17 EJP62346.1 - 4.6e-24 85.0 0.0 6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Toxin_16 PF07945.11 EJP62347.1 - 0.0051 16.7 11.7 0.0062 16.4 11.7 1.2 1 0 0 1 1 1 1 Janus-atracotoxin Toxin_12 PF07740.12 EJP62347.1 - 0.014 16.1 3.6 0.016 15.9 3.6 1.2 1 0 0 1 1 1 0 Ion channel inhibitory toxin HD_assoc PF13286.6 EJP62349.1 - 0.91 10.1 6.4 0.66 10.5 3.1 2.2 1 1 1 2 2 2 0 Phosphohydrolase-associated domain FliT PF05400.13 EJP62349.1 - 2.6 8.9 16.7 0.11 13.3 7.8 2.8 1 1 2 3 3 3 0 Flagellar protein FliT V_ATPase_I PF01496.19 EJP62349.1 - 8.7 4.1 6.6 11 3.8 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Arv1 PF04161.13 EJP62352.1 - 5.3e-77 258.7 0.0 6.7e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 EJP62353.1 - 2.5e-23 82.3 1.8 2.8e-23 82.2 1.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Git3 PF11710.8 EJP62353.1 - 0.015 15.1 0.2 0.016 15.0 0.2 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF4131 PF13567.6 EJP62353.1 - 0.16 11.6 1.7 0.17 11.5 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NAD_binding_2 PF03446.15 EJP62354.1 - 2.4e-28 99.3 0.1 4.8e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EJP62354.1 - 6.6e-09 36.2 1.0 3.5e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EJP62354.1 - 7.5e-09 35.8 0.2 2.6e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 EJP62354.1 - 3.3e-08 33.8 0.1 7.5e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sacchrp_dh_NADP PF03435.18 EJP62354.1 - 0.027 14.7 0.4 0.15 12.3 0.0 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EJP62354.1 - 0.027 14.4 0.2 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 KR domain GFO_IDH_MocA PF01408.22 EJP62354.1 - 0.028 15.2 0.2 0.079 13.8 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Sif PF06767.11 EJP62354.1 - 0.032 13.2 0.1 0.045 12.7 0.1 1.1 1 0 0 1 1 1 0 Sif protein NAD_binding_10 PF13460.6 EJP62354.1 - 0.042 13.7 0.5 0.042 13.7 0.5 1.7 2 0 0 2 2 2 0 NAD(P)H-binding NAT PF04768.13 EJP62355.1 - 5.7e-53 179.1 0.0 1.2e-52 178.0 0.0 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase BAR_2 PF10455.9 EJP62356.1 - 1.1e-58 198.7 2.0 1.8e-58 198.0 2.0 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EJP62356.1 - 1.3e-21 77.3 7.4 1.6e-20 73.8 7.4 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EJP62356.1 - 0.00061 19.6 1.6 0.0099 15.6 0.3 2.3 2 0 0 2 2 2 1 BAR domain of APPL family FapA PF03961.13 EJP62356.1 - 0.25 9.9 5.0 0.37 9.3 1.5 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A STG PF15809.5 EJP62356.1 - 0.25 11.4 1.5 0.91 9.6 0.3 2.0 2 0 0 2 2 2 0 Simian taste bud-specific gene product family YtxH PF12732.7 EJP62356.1 - 0.52 10.9 2.9 1.9 9.1 0.2 2.6 2 0 0 2 2 2 0 YtxH-like protein GCP_C_terminal PF04130.13 EJP62356.1 - 1.4 8.3 4.3 16 4.9 4.3 2.1 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal ETC_C1_NDUFA5 PF04716.14 EJP62357.1 - 7e-23 80.2 5.6 2.2e-22 78.6 0.0 2.5 3 0 0 3 3 3 2 ETC complex I subunit conserved region FA_desaturase PF00487.24 EJP62358.1 - 3.5e-23 82.8 23.0 5.9e-23 82.0 23.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EJP62358.1 - 6.5e-08 32.9 0.1 1.1e-07 32.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Methyltransf_21 PF05050.12 EJP62359.1 - 2.7e-19 69.8 0.0 3.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 EJP62359.1 - 2.8e-05 23.5 0.0 5.8e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Vibrio cholerae RfbT protein UDPGT PF00201.18 EJP62360.1 - 4.9e-10 38.8 0.0 2.4e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Secapin PF17521.2 EJP62360.1 - 0.064 13.1 0.4 0.16 11.8 0.4 1.7 1 0 0 1 1 1 0 Honey bee peptides HSP20 PF00011.21 EJP62362.1 - 1.4e-18 66.9 0.0 5.3e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EJP62362.1 - 4.8e-05 22.8 0.0 0.0008 18.9 0.0 2.3 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GMC_oxred_N PF00732.19 EJP62363.1 - 1.3e-44 152.8 0.0 1.9e-44 152.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP62363.1 - 4.9e-38 130.9 0.0 7.9e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EJP62363.1 - 1.2e-06 28.3 0.1 0.00047 19.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP62363.1 - 3.4e-06 26.4 1.3 3.9e-05 22.9 1.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EJP62363.1 - 1.6e-05 24.3 0.1 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP62363.1 - 0.00095 19.4 1.2 0.0022 18.2 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EJP62363.1 - 0.0078 15.5 0.5 0.6 9.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP62363.1 - 0.014 14.5 0.2 0.025 13.7 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EJP62363.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EJP62363.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EJP62363.1 - 0.018 14.4 2.3 0.093 12.1 0.8 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EJP62363.1 - 0.019 13.8 0.0 0.065 12.1 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase DUF4683 PF15735.5 EJP62363.1 - 0.05 13.2 0.2 0.073 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) DUF2126 PF09899.9 EJP62363.1 - 0.11 10.6 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) HI0933_like PF03486.14 EJP62363.1 - 0.19 10.4 1.0 0.47 9.1 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EJP62363.1 - 0.26 11.9 1.9 15 6.2 0.7 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP62364.1 - 2.2e-16 60.0 1.9 1.9e-11 43.8 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain ADC PF06314.11 EJP62364.1 - 3.4e-13 49.7 0.0 5.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 EJP62364.1 - 3.5e-07 29.7 0.2 5.2e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP62364.1 - 2.8e-06 27.5 0.8 6.8e-06 26.2 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP62364.1 - 0.0001 21.6 6.6 0.00028 20.1 3.8 2.2 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 EJP62364.1 - 0.0044 16.1 0.3 0.0072 15.5 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EJP62364.1 - 0.0064 15.9 1.5 0.012 15.0 1.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP62364.1 - 0.0075 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP62364.1 - 0.17 10.6 0.4 0.29 9.8 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 EJP62364.1 - 0.39 10.2 4.1 0.57 9.7 3.5 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Glyoxalase PF00903.25 EJP62365.1 - 1.1e-09 38.6 4.4 2.2e-09 37.6 2.4 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EJP62365.1 - 0.00018 21.8 0.8 0.0015 18.8 0.7 2.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TcpQ PF10671.9 EJP62365.1 - 0.041 14.0 0.3 0.096 12.8 0.3 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Cupin_2 PF07883.11 EJP62366.1 - 5e-05 22.9 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EJP62366.1 - 0.036 13.8 0.0 0.081 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Auxin_BP PF02041.16 EJP62366.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Auxin binding protein DUF3653 PF12375.8 EJP62367.1 - 0.038 14.1 0.1 0.061 13.4 0.1 1.3 1 0 0 1 1 1 0 Phage protein PepX_C PF08530.10 EJP62368.1 - 4.5e-39 134.7 0.0 6.2e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EJP62368.1 - 5e-39 134.5 0.0 8.3e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EJP62368.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S8 PF00082.22 EJP62369.1 - 6.2e-42 143.9 0.2 6.2e-42 143.9 0.2 1.9 2 0 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 EJP62369.1 - 7.8e-17 62.0 0.0 2.1e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 EJP62369.1 - 0.0031 17.3 0.0 0.049 13.5 0.0 2.5 2 0 0 2 2 2 1 FlgD Ig-like domain DUF4232 PF14016.6 EJP62369.1 - 0.066 13.4 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) DUF4352 PF11611.8 EJP62369.1 - 0.078 13.3 0.2 1.4 9.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4352) TraK PF06586.11 EJP62369.1 - 0.41 10.3 2.1 0.93 9.1 0.8 2.2 2 0 0 2 2 2 0 TraK protein I-EGF_1 PF18372.1 EJP62369.1 - 2.6 8.2 3.6 13 6.0 0.1 2.4 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 TRI5 PF06330.11 EJP62370.1 - 1.2e-152 508.0 4.9 2.5e-151 503.6 4.9 2.1 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) Beta-lactamase PF00144.24 EJP62370.1 - 4.2e-38 131.4 5.2 7.1e-38 130.7 5.2 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF1816 PF08846.10 EJP62370.1 - 0.0057 16.6 0.1 0.018 15.0 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF1816) TFIIA_gamma_N PF02268.16 EJP62370.1 - 0.044 13.8 0.2 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Transferase PF02458.15 EJP62371.1 - 2.1e-21 76.1 0.0 4.9e-19 68.3 0.0 2.0 2 0 0 2 2 2 2 Transferase family p450 PF00067.22 EJP62372.1 - 8.5e-49 166.5 0.0 1.4e-48 165.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 EJP62373.1 - 5.5e-68 229.5 0.0 7.1e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EJP62373.1 - 7.9e-18 64.4 0.0 3.1e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 Condensation domain GH3 PF03321.13 EJP62373.1 - 0.024 13.5 0.0 0.37 9.6 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Abhydrolase_3 PF07859.13 EJP62374.1 - 5.5e-48 163.6 0.1 6.7e-48 163.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EJP62374.1 - 5.1e-06 25.6 0.4 1.1e-05 24.6 0.4 1.4 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EJP62374.1 - 0.096 11.5 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Steryl acetyl hydrolase Esterase_phd PF10503.9 EJP62374.1 - 0.42 10.1 1.5 8.5 5.8 1.5 2.2 1 1 0 1 1 1 0 Esterase PHB depolymerase Condensation PF00668.20 EJP62375.1 - 3.6e-20 72.1 0.0 1.8e-19 69.8 0.0 1.8 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EJP62375.1 - 4.3e-05 23.8 0.0 0.00013 22.3 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site SUIM_assoc PF16619.5 EJP62377.1 - 0.04 14.0 6.3 0.13 12.3 6.3 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-C4pol PF14260.6 EJP62377.1 - 0.098 13.1 0.1 0.32 11.5 0.1 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Spt20 PF12090.8 EJP62377.1 - 0.2 11.2 3.7 0.3 10.7 3.7 1.2 1 0 0 1 1 1 0 Spt20 family Tri3 PF07428.11 EJP62378.1 - 1.9e-223 741.8 0.0 2.2e-223 741.6 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.12 EJP62378.1 - 0.0009 17.9 0.0 0.78 8.2 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase p450 PF00067.22 EJP62379.1 - 1.9e-65 221.4 0.0 2.7e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EJP62380.1 - 1.1e-69 235.4 0.0 1.2e-69 235.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 EJP62381.1 - 1.2e-32 113.2 0.0 1.4e-31 109.6 0.0 1.9 1 1 0 1 1 1 1 Transferase family MFS_1 PF07690.16 EJP62382.1 - 2.5e-30 105.6 4.1 3.3e-30 105.2 4.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP62382.1 - 1.8e-10 39.9 2.2 8.6e-09 34.3 1.4 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EJP62382.1 - 5.9e-10 38.6 5.5 8.8e-10 38.0 5.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EJP62382.1 - 0.003 16.0 5.0 0.0045 15.5 5.0 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Endotoxin_N PF03945.14 EJP62384.1 - 1.4e-10 41.3 0.0 7.6e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain LysM PF01476.20 EJP62385.1 - 0.0051 16.8 0.0 0.0099 15.9 0.0 1.5 1 0 0 1 1 1 1 LysM domain Orthopox_C10L PF07020.11 EJP62385.1 - 0.04 14.7 0.1 15 6.4 0.0 2.8 2 1 0 2 2 2 0 Orthopoxvirus C10L protein Fungal_trans PF04082.18 EJP62386.1 - 1.8e-36 125.6 0.0 1.8e-36 125.6 0.0 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP62386.1 - 7.5e-08 32.4 8.7 1.3e-07 31.7 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EOS1 PF12326.8 EJP62386.1 - 0.051 13.5 1.2 0.11 12.5 1.2 1.5 1 0 0 1 1 1 0 N-glycosylation protein FAM176 PF14851.6 EJP62386.1 - 0.27 10.9 5.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 FAM176 family TERB2 PF15101.6 EJP62386.1 - 0.98 9.4 8.5 1.4 8.9 7.1 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TFIIA PF03153.13 EJP62386.1 - 1 9.3 17.9 0.051 13.6 11.8 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 EJP62386.1 - 3.4 8.7 10.7 0.49 11.4 5.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) bZIP_Maf PF03131.17 EJP62386.1 - 7.7 7.1 17.2 17 6.0 17.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor PigN PF04987.14 EJP62388.1 - 2.2e-162 541.1 36.1 2.2e-162 541.1 36.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EJP62388.1 - 1.1e-09 38.4 5.0 5.6e-08 32.8 5.0 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EJP62388.1 - 2.3e-07 30.5 0.7 3.8e-07 29.8 0.1 1.6 2 0 0 2 2 2 1 Sulfatase Flavi_NS2A PF01005.19 EJP62388.1 - 0.00031 21.0 1.2 0.001 19.2 1.2 1.9 1 0 0 1 1 1 1 Flavivirus non-structural protein NS2A ABC_tran PF00005.27 EJP62389.1 - 1.4e-51 174.6 0.7 2.3e-32 112.4 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP62389.1 - 2.5e-21 76.5 19.0 5.1e-11 42.7 9.8 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP62389.1 - 1e-07 31.7 7.0 0.0044 16.5 1.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP62389.1 - 2.5e-07 30.8 2.9 0.11 12.3 0.1 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EJP62389.1 - 3.1e-07 31.1 0.9 0.0012 19.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJP62389.1 - 4.6e-07 29.5 0.8 0.013 15.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP62389.1 - 1.7e-06 28.6 1.4 0.023 15.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EJP62389.1 - 1.8e-06 28.0 0.1 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 EJP62389.1 - 2.8e-05 23.3 0.2 0.054 12.5 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EJP62389.1 - 3.9e-05 23.7 0.1 0.02 15.0 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EJP62389.1 - 5.6e-05 23.4 2.5 0.21 11.8 0.1 3.2 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EJP62389.1 - 0.00022 20.8 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EJP62389.1 - 0.00042 20.9 0.2 0.17 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EJP62389.1 - 0.00049 19.5 0.1 0.33 10.3 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Pox_A32 PF04665.12 EJP62389.1 - 0.00086 18.8 1.2 0.45 9.9 0.1 2.5 2 0 0 2 2 2 2 Poxvirus A32 protein cobW PF02492.19 EJP62389.1 - 0.0038 16.8 4.1 0.14 11.8 0.4 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EJP62389.1 - 0.0085 16.0 0.0 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 EJP62389.1 - 0.0097 15.6 0.2 1.4 8.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EJP62389.1 - 0.012 15.3 0.1 6 6.5 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EJP62389.1 - 0.014 15.2 0.1 10 5.8 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 EJP62389.1 - 0.014 15.6 0.1 9.4 6.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 EJP62389.1 - 0.014 14.6 0.1 0.34 10.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 EJP62389.1 - 0.018 14.2 4.8 1.8 7.7 0.3 3.7 3 1 0 3 3 3 0 NB-ARC domain MobB PF03205.14 EJP62389.1 - 0.028 14.3 1.3 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 EJP62389.1 - 0.031 14.3 5.6 0.64 10.1 0.4 2.4 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 EJP62389.1 - 0.033 14.4 0.4 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 EJP62389.1 - 0.036 13.0 0.9 5.9 5.7 0.1 2.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 EJP62389.1 - 0.041 14.0 4.9 0.062 13.4 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 EJP62389.1 - 0.068 12.9 2.3 2.6 7.7 0.5 3.1 3 1 0 3 3 2 0 AAA domain NACHT PF05729.12 EJP62389.1 - 0.084 12.8 3.1 11 5.9 0.1 3.0 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 EJP62389.1 - 0.086 12.1 0.2 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EJP62389.1 - 0.1 12.1 0.3 6.6 6.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_10 PF12846.7 EJP62389.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.18 EJP62389.1 - 0.13 11.5 0.0 9 5.5 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 EJP62389.1 - 0.14 11.9 0.8 6.5 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EJP62389.1 - 0.18 11.8 0.2 37 4.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 EJP62389.1 - 0.21 12.0 0.2 5.7 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 EJP62389.1 - 0.25 10.7 2.0 1.1 8.6 0.0 2.5 3 0 0 3 3 2 0 AIG1 family AAA_28 PF13521.6 EJP62389.1 - 0.25 11.6 3.4 3.4 7.9 0.2 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EJP62389.1 - 0.36 10.7 1.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 NTPase DUF3328 PF11807.8 EJP62390.1 - 5.1e-06 26.4 0.2 5.6e-06 26.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_tran PF00005.27 EJP62391.1 - 7.6e-32 110.7 0.0 1.5e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EJP62391.1 - 2.4e-17 63.5 7.2 2.4e-17 63.5 7.2 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region PAM2 PF07145.15 EJP62391.1 - 0.00056 19.4 0.1 0.0014 18.1 0.1 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_21 PF13304.6 EJP62391.1 - 0.00075 19.4 0.7 0.023 14.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EJP62391.1 - 0.0013 18.0 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 EJP62391.1 - 0.0013 18.6 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EJP62391.1 - 0.0015 18.0 0.0 0.011 15.2 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP62391.1 - 0.035 13.8 0.1 0.084 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP62391.1 - 0.051 14.0 0.2 0.2 12.1 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EJP62391.1 - 0.098 13.1 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EJP62391.1 - 0.1 12.3 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EJP62391.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EJP62391.1 - 0.23 11.1 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 EJP62391.1 - 1.2 9.5 3.0 4.7 7.5 0.3 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SGTA_dimer PF16546.5 EJP62392.1 - 3.9e-25 87.4 1.4 7.2e-25 86.6 1.4 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 EJP62392.1 - 2.9e-14 51.9 6.8 2.2e-05 24.2 0.3 4.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EJP62392.1 - 1e-13 50.4 6.3 4.6e-06 26.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EJP62392.1 - 1.4e-08 34.3 5.9 4.6e-05 23.0 0.7 3.2 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 EJP62392.1 - 5.4e-08 32.4 3.1 0.048 13.9 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EJP62392.1 - 6.4e-06 26.6 6.8 0.00094 19.6 1.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJP62392.1 - 2.5e-05 24.8 21.4 0.00017 22.2 5.4 3.4 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJP62392.1 - 2.7e-05 24.2 4.0 0.0047 17.2 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP62392.1 - 3.5e-05 23.5 2.3 0.0087 16.0 0.1 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat STI1 PF17830.1 EJP62392.1 - 7.4e-05 22.6 9.6 0.00039 20.3 5.9 2.5 2 0 0 2 2 2 1 STI1 domain TPR_12 PF13424.6 EJP62392.1 - 0.00016 21.9 7.7 0.00029 21.1 3.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EJP62392.1 - 0.00024 21.6 17.3 0.013 16.2 0.5 4.2 3 1 2 5 5 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EJP62392.1 - 0.0062 16.6 3.0 0.092 12.9 0.6 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 EJP62392.1 - 0.012 16.1 4.4 0.26 11.7 0.9 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain XPC-binding PF09280.11 EJP62392.1 - 0.013 15.2 1.2 0.022 14.5 0.5 1.7 2 0 0 2 2 2 0 XPC-binding domain TPR_6 PF13174.6 EJP62392.1 - 0.022 15.4 7.3 2.3 9.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EJP62392.1 - 0.056 13.3 5.0 1.7 8.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EJP62392.1 - 0.16 12.0 3.1 2.1 8.5 0.2 2.8 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 EJP62392.1 - 0.17 11.9 1.0 0.41 10.7 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RINGv PF12906.7 EJP62393.1 - 0.00035 20.6 7.5 0.00058 19.9 7.5 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EJP62393.1 - 0.016 15.3 4.8 0.032 14.4 4.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 EJP62393.1 - 0.018 15.4 10.0 0.028 14.8 10.0 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 EJP62393.1 - 1.5 8.7 8.9 2.4 8.0 8.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 EJP62393.1 - 8.2 6.4 6.8 13 5.8 6.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3742 PF12553.8 EJP62394.1 - 1.9 8.6 5.5 0.59 10.3 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) GalKase_gal_bdg PF10509.9 EJP62395.1 - 3e-19 68.3 0.3 8.9e-19 66.8 0.1 1.9 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EJP62395.1 - 1.6e-13 50.8 0.1 7.4e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EJP62395.1 - 2.9e-13 49.8 2.4 7.6e-13 48.5 2.4 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1451 PF07295.11 EJP62395.1 - 0.1 12.7 0.5 0.24 11.4 0.3 1.7 2 0 0 2 2 2 0 Zinc-ribbon containing domain zf-H2C2_5 PF13909.6 EJP62396.1 - 0.16 11.7 1.5 3.7 7.4 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EJP62397.1 - 0.06 13.8 10.2 1.3 9.6 1.8 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type SET_assoc PF11767.8 EJP62397.1 - 0.15 11.8 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated GBS_Bsp-like PF08481.10 EJP62397.1 - 1.1 9.4 3.8 0.92 9.7 1.7 1.9 2 0 0 2 2 2 0 GBS Bsp-like repeat DUF4794 PF16042.5 EJP62397.1 - 8.8 7.4 11.2 2.3 9.3 2.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4794) TPP_enzyme_N PF02776.18 EJP62398.1 - 1.1e-55 187.9 0.2 1.1e-53 181.3 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EJP62398.1 - 2.1e-48 164.0 1.1 3.1e-47 160.2 0.1 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJP62398.1 - 5.7e-42 142.7 1.0 1.5e-41 141.3 0.5 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.16 EJP62399.1 - 3.8e-37 128.0 52.8 3.8e-37 128.0 52.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Cutinase PF01083.22 EJP62400.1 - 2.4e-39 135.1 1.6 3.6e-39 134.5 1.6 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EJP62400.1 - 0.0072 15.9 1.1 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 PE-PPE domain PAP1 PF08601.10 EJP62400.1 - 0.08 12.7 3.7 0.11 12.2 3.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 TMEM154 PF15102.6 EJP62400.1 - 0.13 12.2 0.5 0.2 11.6 0.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family AcMNPV_Ac109 PF05054.12 EJP62400.1 - 0.26 10.3 0.4 0.43 9.6 0.0 1.4 2 0 0 2 2 2 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein zf-CCCH_3 PF15663.5 EJP62402.1 - 0.043 14.0 0.1 0.052 13.8 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger containing family ABC_tran PF00005.27 EJP62404.1 - 3.4e-34 118.3 0.0 1.9e-18 67.3 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP62404.1 - 1.3e-14 54.5 21.8 2.6e-14 53.5 9.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP62404.1 - 1.8e-12 47.2 0.2 2.8e-06 27.0 0.1 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EJP62404.1 - 4e-08 33.8 0.0 0.0026 18.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EJP62404.1 - 8.5e-07 28.6 0.1 0.059 13.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP62404.1 - 3e-05 24.3 0.1 0.31 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EJP62404.1 - 5e-05 23.3 0.0 0.059 13.3 0.0 2.4 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_21 PF13304.6 EJP62404.1 - 5.7e-05 23.1 0.4 3.5 7.3 0.1 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EJP62404.1 - 0.00042 20.3 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 EJP62404.1 - 0.00066 19.6 2.0 1.8 8.4 0.0 3.4 3 0 0 3 3 3 2 NACHT domain AAA_25 PF13481.6 EJP62404.1 - 0.0012 18.4 0.4 1.7 8.2 0.1 3.1 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EJP62404.1 - 0.0031 18.1 0.0 0.3 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EJP62404.1 - 0.0042 17.1 0.6 2.3 8.3 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EJP62404.1 - 0.0083 16.5 0.6 1.5 9.2 0.1 3.3 3 0 0 3 3 3 1 RNA helicase DUF2678 PF10856.8 EJP62404.1 - 0.011 15.6 1.8 0.05 13.6 1.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) AAA PF00004.29 EJP62404.1 - 0.015 15.8 0.2 11 6.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EJP62404.1 - 0.019 14.7 0.2 2 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EJP62404.1 - 0.041 13.2 0.0 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 EJP62404.1 - 0.048 12.8 0.1 0.42 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 EJP62404.1 - 0.05 13.3 0.2 3.8 7.2 0.1 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 EJP62404.1 - 0.063 12.5 4.9 5.8 6.0 0.2 4.0 3 1 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.6 EJP62404.1 - 0.083 12.6 1.7 6 6.5 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EJP62404.1 - 0.1 12.6 0.4 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EJP62404.1 - 0.15 11.7 0.0 7.8 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EJP62404.1 - 0.29 11.0 0.5 60 3.5 0.0 3.6 4 0 0 4 4 4 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EJP62404.1 - 1 9.1 4.2 21 4.8 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein DnaI_N PF07319.11 EJP62405.1 - 0.069 13.8 2.0 0.17 12.6 2.0 1.6 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus DUF4164 PF13747.6 EJP62406.1 - 0.002 18.4 3.2 0.075 13.3 0.8 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) Filament PF00038.21 EJP62406.1 - 0.028 14.0 0.7 0.049 13.2 0.7 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF4140 PF13600.6 EJP62406.1 - 0.038 14.4 0.7 0.11 13.0 0.7 1.9 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.18 EJP62406.1 - 0.11 12.7 1.8 0.53 10.5 1.5 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper ATG16 PF08614.11 EJP62406.1 - 0.75 10.0 8.7 0.66 10.2 7.5 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4355 PF14265.6 EJP62406.1 - 2 8.7 5.8 2.6 8.3 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) HSP70 PF00012.20 EJP62407.1 - 2.9e-12 45.6 0.3 5e-12 44.8 0.0 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EJP62407.1 - 1.5e-06 27.3 0.1 9.4e-05 21.4 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein PE_PPE_C PF12484.8 EJP62407.1 - 0.31 12.0 2.9 0.58 11.1 0.6 2.2 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal Acetyltransf_3 PF13302.7 EJP62408.1 - 4.9e-14 53.2 0.0 6.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP62408.1 - 6.2e-07 29.7 0.1 9e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EJP62408.1 - 0.011 15.4 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP62408.1 - 0.05 14.0 0.1 0.081 13.4 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LPD26 PF18842.1 EJP62408.1 - 0.14 12.1 0.0 0.59 10.1 0.0 1.9 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 Kinesin PF00225.23 EJP62409.1 - 5.5e-51 173.5 0.0 2.5e-30 105.5 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EJP62409.1 - 4.3e-07 30.0 0.0 7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Pre-PUA PF17832.1 EJP62411.1 - 9e-21 74.4 0.3 1.3e-20 73.8 0.3 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EJP62411.1 - 6.3e-12 45.3 0.6 1.2e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 PUA domain Inhibitor_I78 PF11720.8 EJP62412.1 - 1.3e-06 28.4 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EJP62412.1 - 9.8e-06 26.2 0.2 1.3e-05 25.7 0.2 1.2 1 0 0 1 1 1 1 Potato inhibitor I family DUF2924 PF11149.8 EJP62412.1 - 0.0019 18.6 0.2 0.0019 18.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2924) PHO4 PF01384.20 EJP62413.1 - 0.074 12.1 0.4 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Phosphate transporter family NST1 PF13945.6 EJP62414.1 - 1e-46 159.5 16.4 1e-46 159.5 16.4 5.2 3 2 1 4 4 4 1 Salt tolerance down-regulator Ras PF00071.22 EJP62415.1 - 2e-49 167.3 0.0 2.3e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP62415.1 - 2.3e-21 76.2 0.0 3.1e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP62415.1 - 5.9e-06 25.8 0.0 9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EJP62415.1 - 0.039 13.4 0.0 0.063 12.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 EJP62415.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Gtr1_RagA PF04670.12 EJP62415.1 - 0.064 12.6 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJP62415.1 - 0.13 12.3 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MRP-L28 PF09812.9 EJP62416.1 - 0.0021 18.2 0.1 0.0046 17.1 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RRM_1 PF00076.22 EJP62418.1 - 0.19 11.6 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 EJP62419.1 - 1.3e-06 28.4 10.2 2.2e-06 27.7 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP62419.1 - 0.00022 20.1 0.0 0.0004 19.3 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_3 PF13302.7 EJP62420.1 - 1.4e-17 64.7 0.1 1.7e-17 64.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP62420.1 - 3.5e-05 24.0 0.0 5.6e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 EJP62420.1 - 0.0015 18.2 0.0 0.0019 17.9 0.0 1.3 1 1 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_4 PF13420.7 EJP62420.1 - 0.004 17.3 0.0 0.0054 16.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain bPH_6 PF10756.9 EJP62420.1 - 0.09 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain AAA PF00004.29 EJP62421.1 - 1.3e-15 58.0 0.0 3.5e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJP62421.1 - 0.0013 19.1 0.0 0.0044 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP62421.1 - 0.006 16.9 0.0 0.03 14.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 EJP62421.1 - 0.022 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 EJP62421.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EJP62421.1 - 0.045 13.3 0.3 0.92 9.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EJP62421.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 EJP62421.1 - 0.054 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJP62421.1 - 0.057 13.5 0.0 0.52 10.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.16 EJP62421.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 EJP62421.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EJP62421.1 - 0.15 11.4 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 KaiC MFS_1 PF07690.16 EJP62422.1 - 1.8e-19 69.9 41.2 3.4e-17 62.4 14.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfotransfer_4 PF17784.1 EJP62423.1 - 1.9e-74 250.1 0.2 2.5e-74 249.7 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EJP62423.1 - 0.00016 22.2 0.9 0.013 15.9 0.9 2.3 1 1 0 1 1 1 1 Sulfotransferase family ACOX PF01756.19 EJP62424.1 - 1.2e-39 135.7 0.2 2.2e-39 134.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EJP62424.1 - 4.6e-22 78.9 0.1 1.1e-21 77.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EJP62424.1 - 1.2e-06 28.6 0.0 4.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EJP62424.1 - 0.043 14.0 0.7 0.39 10.9 0.7 2.2 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Transglut_core PF01841.19 EJP62425.1 - 0.15 12.5 0.0 0.26 11.8 0.0 1.5 2 0 0 2 2 2 0 Transglutaminase-like superfamily Pkinase PF00069.25 EJP62426.1 - 1.4e-51 175.4 0.0 1.9e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62426.1 - 1.3e-25 90.2 0.0 4.1e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EJP62426.1 - 0.023 14.3 1.3 0.041 13.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 EJP62426.1 - 0.035 13.1 0.1 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 EJP62427.1 - 2.1e-52 178.1 0.0 2.9e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62427.1 - 2.2e-29 102.5 0.0 3.1e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP62427.1 - 4.7e-05 22.9 0.0 0.00016 21.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EJP62427.1 - 0.0002 21.4 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EJP62427.1 - 0.0031 16.9 0.1 0.0054 16.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EJP62427.1 - 0.012 15.2 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 UL11 PF11094.8 EJP62427.1 - 0.03 14.2 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein Pkinase_fungal PF17667.1 EJP62427.1 - 0.037 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EJP62427.1 - 0.038 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EJP62427.1 - 0.089 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase NTP_transf_6 PF06042.11 EJP62429.1 - 1.9e-51 174.1 0.1 2.3e-51 173.8 0.1 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase HlyIII PF03006.20 EJP62430.1 - 4.6e-58 196.6 13.2 5.6e-58 196.3 13.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2749 PF10907.8 EJP62430.1 - 0.39 10.9 1.5 2.7 8.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF4231 PF14015.6 EJP62430.1 - 2.6 8.5 5.3 8.2 7.0 0.3 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) ANAPC4_WD40 PF12894.7 EJP62431.1 - 5.9e-06 26.5 0.0 0.13 12.6 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 EJP62431.1 - 0.053 12.1 0.0 0.082 11.5 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin BUD22 PF09073.10 EJP62431.1 - 0.54 9.6 18.5 0.18 11.1 9.1 2.1 2 0 0 2 2 2 0 BUD22 YL1 PF05764.13 EJP62431.1 - 0.74 9.9 12.8 0.034 14.3 4.6 2.1 2 0 0 2 2 2 0 YL1 nuclear protein DUF4111 PF13427.6 EJP62433.1 - 0.17 12.1 2.2 6.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) F-box PF00646.33 EJP62434.1 - 7.1e-05 22.6 1.3 7.1e-05 22.6 1.3 2.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EJP62434.1 - 0.009 15.9 0.1 0.009 15.9 0.1 2.6 2 1 1 3 3 3 1 F-box-like ABC_tran PF00005.27 EJP62435.1 - 8.1e-39 133.3 0.0 2.5e-21 76.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP62435.1 - 3.5e-26 92.5 28.8 1.1e-15 58.1 17.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP62435.1 - 1.8e-12 47.2 0.0 1.8e-05 24.3 0.1 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP62435.1 - 0.00014 21.5 0.3 0.043 13.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EJP62435.1 - 0.00022 21.1 6.4 0.011 15.6 0.2 3.6 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EJP62435.1 - 0.00037 20.8 0.1 0.47 10.7 0.1 2.9 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EJP62435.1 - 0.001 19.3 0.6 1.1 9.6 0.1 2.9 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EJP62435.1 - 0.0012 18.7 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EJP62435.1 - 0.0045 17.5 0.1 0.25 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EJP62435.1 - 0.01 15.9 3.3 1.7 8.7 0.3 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase T2SSE PF00437.20 EJP62435.1 - 0.011 14.8 0.5 3.1 6.8 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein Dynamin_N PF00350.23 EJP62435.1 - 0.056 13.5 2.5 3.2 7.8 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 EJP62435.1 - 0.15 12.6 0.0 6.6 7.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EJP62435.1 - 0.17 11.1 0.1 9.3 5.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin adh_short_C2 PF13561.6 EJP62436.1 - 8.4e-50 169.5 5.0 3.1e-40 138.2 2.2 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP62436.1 - 2.3e-44 151.2 2.5 2.9e-44 150.9 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP62436.1 - 5.5e-16 59.0 0.5 7.5e-16 58.5 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EJP62436.1 - 0.0024 17.8 0.7 0.0044 16.9 0.7 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EJP62436.1 - 0.0075 16.3 0.3 0.012 15.7 0.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EJP62436.1 - 0.049 13.2 0.2 0.093 12.3 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glycos_transf_2 PF00535.26 EJP62437.1 - 1.5e-34 119.2 0.0 1.8e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EJP62437.1 - 2.5e-13 50.5 0.0 3e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EJP62437.1 - 5.4e-05 22.8 0.0 7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EJP62437.1 - 0.00011 21.7 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Epimerase PF01370.21 EJP62438.1 - 9.5e-08 31.8 0.0 0.0023 17.4 0.0 2.1 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EJP62438.1 - 0.00021 20.5 0.0 0.027 13.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EJP62438.1 - 0.00049 19.6 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EJP62438.1 - 0.004 16.2 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EJP62438.1 - 0.013 14.7 0.0 5.7 6.0 0.0 2.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EJP62438.1 - 0.028 13.5 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 EJP62438.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 KR domain FAD_binding_4 PF01565.23 EJP62439.1 - 1.5e-20 73.3 0.3 2.2e-20 72.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain DUF4037 PF13228.6 EJP62439.1 - 0.1 13.4 0.3 27 5.6 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4037) FMN_dh PF01070.18 EJP62440.1 - 2.6e-105 352.3 0.0 3.2e-105 352.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EJP62440.1 - 0.0014 17.7 1.0 0.0032 16.5 1.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 EJP62440.1 - 0.0041 16.5 0.7 0.9 8.8 1.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG p450 PF00067.22 EJP62441.1 - 1.7e-72 244.6 0.0 2.2e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF915 PF06028.11 EJP62441.1 - 0.22 10.8 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF4519 PF15012.6 EJP62441.1 - 0.24 11.6 0.5 0.44 10.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) SKG6 PF08693.10 EJP62442.1 - 3.6e-06 26.3 0.2 3.6e-06 26.3 0.2 2.2 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF3632 PF12311.8 EJP62443.1 - 1.4e-24 87.5 0.0 1.7e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Antifungal_prot PF11402.8 EJP62444.1 - 8.9e-07 29.1 8.1 1.2e-06 28.7 8.1 1.2 1 0 0 1 1 1 1 Antifungal protein Podoplanin PF05808.11 EJP62445.1 - 0.017 15.2 0.3 0.025 14.7 0.3 1.2 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.10 EJP62445.1 - 0.068 12.6 1.2 0.19 11.2 1.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MSP1_C PF07462.11 EJP62445.1 - 3.4 6.3 7.4 5 5.7 7.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DHQ_synthase PF01761.20 EJP62449.1 - 5.8e-83 278.1 0.6 1.4e-62 211.2 0.0 3.2 3 0 0 3 3 3 2 3-dehydroquinate synthase Epimerase PF01370.21 EJP62449.1 - 1.8e-12 47.2 0.0 4.7e-11 42.6 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 EJP62449.1 - 3.6e-10 39.7 2.7 1.3e-09 37.9 2.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fe-ADH_2 PF13685.6 EJP62449.1 - 2.5e-08 34.0 1.8 5.6e-06 26.2 1.0 3.0 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase ROK PF00480.20 EJP62449.1 - 7.6e-08 32.2 0.0 3.8e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 ROK family NAD_binding_10 PF13460.6 EJP62449.1 - 4.9e-06 26.6 3.7 0.00036 20.5 0.1 3.8 4 0 0 4 4 4 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EJP62449.1 - 7.2e-06 25.2 0.3 1.7e-05 24.0 0.3 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EJP62449.1 - 7.6e-06 25.2 0.0 0.041 13.0 0.0 2.9 3 0 0 3 3 3 2 RmlD substrate binding domain NmrA PF05368.13 EJP62449.1 - 3e-05 23.7 0.9 9.9e-05 22.0 0.9 1.9 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EJP62449.1 - 6.3e-05 22.5 0.2 0.0051 16.2 0.2 2.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EJP62449.1 - 0.00019 21.5 1.9 0.0013 18.8 0.3 2.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EJP62449.1 - 0.00025 20.7 1.2 0.0027 17.4 0.0 3.0 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Fe-ADH PF00465.19 EJP62449.1 - 0.00057 18.8 0.6 0.0016 17.4 0.6 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ADH_zinc_N PF00107.26 EJP62449.1 - 0.0013 18.7 0.1 0.0046 16.9 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_4 PF07993.12 EJP62449.1 - 0.003 16.8 0.0 0.11 11.7 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EJP62449.1 - 0.0051 16.3 4.5 0.048 13.1 0.2 3.4 4 0 0 4 4 4 1 short chain dehydrogenase CobN-Mg_chel PF02514.16 EJP62449.1 - 0.0077 14.0 0.1 0.012 13.4 0.1 1.2 1 0 0 1 1 1 1 CobN/Magnesium Chelatase F420_oxidored PF03807.17 EJP62449.1 - 0.014 15.9 1.5 3.8 8.2 0.0 3.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 EJP62449.1 - 0.039 14.8 0.1 0.15 12.9 0.1 2.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 EJP62449.1 - 0.062 13.2 1.5 2.5 7.9 0.1 2.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EJP62449.1 - 0.24 11.5 4.2 0.52 10.5 0.2 3.1 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EJP62449.1 - 0.3 10.4 7.6 0.11 11.8 1.1 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GMC_oxred_C PF05199.13 EJP62450.1 - 1.3e-12 48.4 0.1 5.8e-12 46.3 0.1 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EJP62450.1 - 2.9e-05 23.6 0.1 0.00039 19.9 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EJP62450.1 - 0.049 13.9 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HAD_2 PF13419.6 EJP62451.1 - 7.5e-21 75.0 0.0 9.7e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP62451.1 - 3.2e-12 47.2 0.0 1.3e-06 28.9 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP62451.1 - 1e-05 25.5 0.1 2.2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EJP62451.1 - 2.3e-05 24.9 0.0 3.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EJP62451.1 - 0.00049 20.2 0.1 0.01 16.0 0.1 2.9 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase GHL6 PF14871.6 EJP62451.1 - 0.028 14.6 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Hydrolase_3 PF08282.12 EJP62451.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 EJP62452.1 - 2.5e-34 118.7 54.1 3.5e-33 115.0 51.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Kelch_6 PF13964.6 EJP62453.1 - 8.9e-18 63.9 1.2 1.3e-07 31.6 0.0 5.0 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 EJP62453.1 - 1.3e-17 63.5 9.2 4.9e-06 26.5 0.1 6.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EJP62453.1 - 3.2e-15 55.7 1.8 0.0028 17.6 0.0 7.2 7 1 0 7 7 7 3 Kelch motif Kelch_3 PF13415.6 EJP62453.1 - 2.4e-14 53.2 9.3 0.0088 16.3 0.1 6.8 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EJP62453.1 - 1.6e-12 46.9 3.1 0.00029 20.7 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EJP62453.1 - 1.3e-10 40.7 0.7 9.9e-06 25.0 0.0 3.6 4 0 0 4 4 4 2 Kelch motif 2Fe-2S_thioredx PF01257.19 EJP62454.1 - 2.7e-57 192.7 0.0 4.1e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Methyltransf_7 PF03492.15 EJP62454.1 - 1.2e-37 129.9 0.0 1.7e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_25 PF13649.6 EJP62455.1 - 4.7e-12 46.4 0.0 1e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP62455.1 - 5.4e-12 46.2 0.0 3.2e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP62455.1 - 7.5e-11 42.7 0.0 1.1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP62455.1 - 1e-09 38.5 0.0 1.3e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP62455.1 - 6.4e-07 28.9 0.0 8.2e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EJP62455.1 - 2.5e-05 24.1 0.0 3.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP62455.1 - 5.4e-05 22.8 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EJP62455.1 - 0.00078 19.3 0.0 0.00099 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 EJP62455.1 - 0.0021 17.7 0.0 0.0028 17.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 EJP62455.1 - 0.0041 18.1 0.0 0.011 16.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EJP62455.1 - 0.0048 16.8 0.0 0.007 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJP62455.1 - 0.0077 15.6 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 EJP62455.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.16 EJP62456.1 - 4.4e-32 111.4 68.2 9.8e-32 110.2 63.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP62456.1 - 9e-07 27.7 29.6 1.5e-05 23.7 29.6 2.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 EJP62457.1 - 3.9e-12 46.0 0.0 9.3e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP62457.1 - 8.7e-07 28.7 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EJP62457.1 - 0.0074 15.7 0.0 0.0094 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DAO PF01266.24 EJP62458.1 - 3.5e-44 151.8 4.9 4.2e-44 151.6 4.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP62458.1 - 3.9e-06 26.2 0.1 7.4e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EJP62458.1 - 0.00026 21.2 0.1 0.00065 19.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EJP62458.1 - 0.0013 18.1 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP62458.1 - 0.0018 17.6 0.3 0.0032 16.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EJP62458.1 - 0.0032 16.8 0.5 0.0065 15.7 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP62458.1 - 0.0041 16.4 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EJP62458.1 - 0.011 15.1 0.4 0.021 14.2 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP62458.1 - 0.016 13.9 0.3 0.098 11.3 0.3 1.9 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EJP62458.1 - 0.074 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 EJP62459.1 - 2e-41 142.1 0.0 5.6e-39 134.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62459.1 - 2.5e-24 85.9 0.0 4.7e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase dCMP_cyt_deam_1 PF00383.23 EJP62460.1 - 1.9e-24 85.4 1.7 2.9e-24 84.8 1.7 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EJP62460.1 - 4.9e-08 32.8 0.1 8.8e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 EJP62460.1 - 0.0069 16.9 0.1 0.014 15.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 EJP62460.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase ATG7_N PF16420.5 EJP62461.1 - 4.5e-111 371.3 0.0 5.6e-111 371.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EJP62461.1 - 2.6e-43 148.2 0.0 3.8e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EJP62461.1 - 0.13 12.4 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pmp3 PF01679.17 EJP62462.1 - 3.2e-24 84.9 9.2 3.5e-24 84.7 9.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PIG-F PF06699.11 EJP62463.1 - 5.1e-58 196.2 3.4 6.3e-58 195.9 3.4 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_Omp PF13488.6 EJP62463.1 - 0.42 10.7 15.8 0.73 9.9 6.6 2.6 2 0 0 2 2 2 0 Glycine zipper Chs7 PF12271.8 EJP62465.1 - 4.1e-111 371.0 6.3 4.6e-111 370.8 6.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Ssl1 PF04056.14 EJP62466.1 - 1.4e-73 246.8 0.0 1.8e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 EJP62466.1 - 2.4e-16 60.3 0.0 4.6e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 EJP62466.1 - 6.5e-15 55.1 11.6 6.5e-15 55.1 11.6 2.6 2 1 0 2 2 2 1 TFIIH C1-like domain Glyoxalase PF00903.25 EJP62467.1 - 3e-21 76.0 0.5 5.2e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EJP62467.1 - 9.5e-10 38.7 0.1 0.002 18.4 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EJP62467.1 - 1.4e-05 25.2 0.5 0.097 12.8 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EJP62467.1 - 0.024 14.8 0.1 0.054 13.7 0.1 1.5 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TRPM_tetra PF16519.5 EJP62468.1 - 0.017 15.2 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Tetramerisation domain of TRPM NAD_binding_11 PF14833.6 EJP62468.1 - 0.031 14.5 0.4 0.1 12.8 0.2 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TPR_11 PF13414.6 EJP62468.1 - 0.19 11.4 0.8 0.98 9.2 0.3 2.2 2 0 0 2 2 2 0 TPR repeat NCE101 PF11654.8 EJP62469.1 - 9.6e-10 38.0 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 Ribosomal_L27e PF01777.18 EJP62470.1 - 8.6e-36 122.2 2.5 1.4e-35 121.5 2.5 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EJP62470.1 - 0.006 16.5 0.9 0.02 14.9 0.9 1.9 1 0 0 1 1 1 1 KOW motif TPT PF03151.16 EJP62471.1 - 6.5e-27 94.6 23.3 8.1e-27 94.3 23.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EJP62471.1 - 4.8e-05 22.7 24.4 0.00018 20.8 24.4 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EJP62471.1 - 0.0026 17.9 40.2 0.0054 16.9 13.5 2.7 3 0 0 3 3 3 2 EamA-like transporter family Amino_oxidase PF01593.24 EJP62472.1 - 1.9e-11 43.9 0.0 2.6e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP62472.1 - 7.4e-07 29.3 0.1 1.7e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP62472.1 - 0.016 14.5 0.2 0.32 10.2 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EJP62472.1 - 0.043 13.2 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1344 PF07076.11 EJP62472.1 - 0.058 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Thi4 PF01946.17 EJP62472.1 - 0.073 12.3 0.1 1 8.6 0.1 2.2 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 EJP62472.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 EJP62472.1 - 0.19 11.0 1.5 0.16 11.2 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mnd1 PF03962.15 EJP62472.1 - 0.19 12.0 0.4 10 6.5 0.0 2.5 2 0 0 2 2 2 0 Mnd1 HTH domain FAD_binding_3 PF01494.19 EJP62472.1 - 0.19 10.9 0.2 0.3 10.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EJP62472.1 - 0.23 10.4 0.2 0.42 9.6 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein CxC7 PF18866.1 EJP62473.1 - 0.13 12.5 0.2 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases HATPase_c PF02518.26 EJP62474.1 - 2.2e-29 102.2 0.0 4.7e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EJP62474.1 - 3.9e-21 75.3 0.2 1.3e-20 73.6 0.2 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EJP62474.1 - 7.5e-18 64.3 1.8 1.6e-17 63.3 0.5 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EJP62474.1 - 5.2e-14 52.7 0.0 4.2e-13 49.8 0.0 2.5 2 0 0 2 2 2 1 GAF domain AAA_16 PF13191.6 EJP62474.1 - 1.9e-10 41.4 0.6 4.3e-09 37.0 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain Pkinase PF00069.25 EJP62474.1 - 1.3e-07 31.3 0.0 2.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 EJP62474.1 - 2.7e-07 31.3 0.0 8.2e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EJP62474.1 - 0.00049 20.4 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.17 EJP62474.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.6 EJP62474.1 - 0.0057 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_12 PF13424.6 EJP62474.1 - 0.049 13.9 3.7 1.1 9.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.7 EJP62476.1 - 7.7e-08 32.1 0.2 2.2e-07 30.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP62476.1 - 0.011 15.6 1.5 0.05 13.5 1.5 2.0 1 1 0 1 1 1 0 F-box domain CENP-B_dimeris PF09026.10 EJP62476.1 - 1.9 8.9 12.5 3.8 8.0 12.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EJP62476.1 - 3.5 5.6 6.5 5.2 5.0 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 EJP62476.1 - 4 7.7 7.5 11 6.3 7.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EJP62476.1 - 4.5 6.5 10.8 6.7 5.9 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein EamA PF00892.20 EJP62477.1 - 7.5e-08 32.6 31.2 2.4e-05 24.5 4.6 2.7 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 EJP62477.1 - 0.00025 20.1 10.0 0.00025 20.1 10.0 2.2 2 1 0 2 2 2 1 Ceramide synthase regulator DUF4579 PF15158.6 EJP62477.1 - 0.17 11.6 1.1 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) Aldo_ket_red PF00248.21 EJP62478.1 - 9.3e-50 169.5 0.0 1.1e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_tran PF00005.27 EJP62479.1 - 3.1e-36 124.9 0.0 2.8e-18 66.7 0.3 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP62479.1 - 4.2e-11 43.0 28.0 1.3e-07 31.6 13.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EJP62479.1 - 1.9e-06 27.9 0.0 0.034 14.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EJP62479.1 - 1e-05 25.1 1.2 0.067 12.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 EJP62479.1 - 1.5e-05 25.2 0.1 0.079 13.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 EJP62479.1 - 3.7e-05 23.3 0.7 0.0049 16.3 0.2 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP62479.1 - 4.5e-05 23.4 3.0 0.22 11.3 1.1 3.3 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EJP62479.1 - 4.8e-05 23.8 0.1 0.66 10.3 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.6 EJP62479.1 - 6e-05 23.4 0.6 0.1 12.9 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 EJP62479.1 - 6.5e-05 23.4 0.2 0.21 12.0 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EJP62479.1 - 6.6e-05 23.0 0.0 0.56 10.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EJP62479.1 - 0.00012 22.7 0.2 0.4 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EJP62479.1 - 0.0029 17.7 4.1 1.5 8.8 3.0 2.6 2 1 0 2 2 2 2 Dynamin family AAA_30 PF13604.6 EJP62479.1 - 0.0047 16.7 1.0 1.1 9.0 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 EJP62479.1 - 0.012 15.1 0.2 5.3 6.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 EJP62479.1 - 0.014 15.7 3.7 0.47 10.7 0.1 3.0 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EJP62479.1 - 0.016 14.8 1.2 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EJP62479.1 - 0.018 14.6 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain CUT PF02376.15 EJP62479.1 - 0.018 15.2 0.1 0.065 13.4 0.0 2.0 2 0 0 2 2 1 0 CUT domain AAA_15 PF13175.6 EJP62479.1 - 0.026 14.3 0.0 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 EJP62479.1 - 0.036 14.0 0.5 10 6.0 0.0 2.8 3 0 0 3 3 3 0 NTPase AAA_18 PF13238.6 EJP62479.1 - 0.041 14.4 0.1 14 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EJP62479.1 - 0.081 13.2 6.2 2 8.6 0.1 3.8 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 EJP62479.1 - 0.097 11.9 0.2 2.4 7.4 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin C_Hendra PF16821.5 EJP62479.1 - 0.11 12.3 3.4 0.13 12.1 1.3 2.0 2 0 0 2 2 2 0 C protein from hendra and measles viruses DUF2828 PF11443.8 EJP62479.1 - 0.11 10.5 0.0 0.18 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AAA_11 PF13086.6 EJP62479.1 - 0.11 12.2 1.9 0.42 10.4 0.0 2.6 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EJP62479.1 - 0.19 10.9 2.4 8.3 5.5 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 EJP62479.1 - 0.19 11.3 0.3 22 4.6 0.1 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 EJP62479.1 - 0.44 10.2 4.1 9.2 5.9 0.6 2.6 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EJP62479.1 - 0.51 10.3 1.6 16 5.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EJP62479.1 - 1.1 9.1 5.1 5.3 6.9 0.1 2.9 3 0 0 3 3 3 0 NACHT domain PPR_3 PF13812.6 EJP62480.1 - 2.6e-09 37.0 0.1 0.031 14.3 0.0 4.7 3 1 1 4 4 4 4 Pentatricopeptide repeat domain TPR_8 PF13181.6 EJP62480.1 - 0.16 12.3 0.4 0.58 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 EJP62481.1 - 4.2e-11 42.9 0.2 1.2e-09 38.3 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein S18 Viral_NABP PF05515.11 EJP62481.1 - 0.062 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Viral nucleic acid binding MSA-2c PF12238.8 EJP62481.1 - 1.7 8.6 3.7 9.4 6.2 3.0 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c Ribosomal_S4 PF00163.19 EJP62482.1 - 9.4e-11 42.5 0.8 1.5e-10 41.9 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EJP62482.1 - 1.3e-09 37.6 0.0 3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain Methyltransf_23 PF13489.6 EJP62483.1 - 0.0042 16.9 0.0 0.025 14.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP62483.1 - 0.054 12.8 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family BTB_2 PF02214.22 EJP62484.1 - 7.3e-08 32.7 0.0 4.3e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain SNF2_N PF00176.23 EJP62485.1 - 2.8e-51 174.3 0.3 5.5e-51 173.3 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EJP62485.1 - 3.5e-26 91.1 0.5 3.5e-26 91.1 0.5 2.4 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EJP62485.1 - 6.7e-19 68.3 0.0 2.7e-18 66.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP62485.1 - 1.2e-09 38.4 1.8 5.2e-07 29.8 0.0 4.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EJP62485.1 - 7.2e-07 28.7 0.0 7.2e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA PF00004.29 EJP62486.1 - 4.5e-15 56.2 0.0 1.1e-14 55.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EJP62486.1 - 5.7e-12 45.9 0.0 1.4e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EJP62486.1 - 3.6e-11 43.1 0.1 2.2e-10 40.6 0.0 2.2 2 1 0 2 2 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EJP62486.1 - 1.3e-06 28.9 0.1 1.3e-05 25.7 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 EJP62486.1 - 1.6e-06 28.1 0.1 0.00016 21.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EJP62486.1 - 2.4e-06 27.8 0.0 7.1e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 EJP62486.1 - 2.9e-06 27.2 0.5 1.4e-05 24.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain DNA_pol3_delta PF06144.13 EJP62486.1 - 4.6e-06 26.5 0.0 8.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EJP62486.1 - 8.5e-06 26.1 0.1 5.3e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EJP62486.1 - 1.5e-05 25.1 0.2 0.00096 19.2 0.1 3.2 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EJP62486.1 - 0.00015 22.1 0.2 0.00051 20.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EJP62486.1 - 0.00023 20.4 0.0 0.0004 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 EJP62486.1 - 0.00056 20.0 0.0 0.033 14.2 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EJP62486.1 - 0.00073 19.4 0.1 0.0054 16.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EJP62486.1 - 0.00098 18.9 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EJP62486.1 - 0.0012 18.7 0.0 0.0039 17.0 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 EJP62486.1 - 0.0014 17.9 0.0 0.0021 17.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EJP62486.1 - 0.0029 17.6 0.0 0.013 15.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 EJP62486.1 - 0.0051 16.3 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein TniB PF05621.11 EJP62486.1 - 0.0067 15.8 0.0 0.095 12.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_28 PF13521.6 EJP62486.1 - 0.0094 16.2 0.1 0.022 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP62486.1 - 0.012 16.1 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EJP62486.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EJP62486.1 - 0.017 14.5 0.1 0.11 11.8 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Hydin_ADK PF17213.3 EJP62486.1 - 0.043 14.1 0.1 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DEAD PF00270.29 EJP62486.1 - 0.055 13.2 0.2 0.65 9.7 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EJP62486.1 - 0.06 12.9 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 EJP62486.1 - 0.068 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EJP62486.1 - 0.089 12.5 0.0 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein TAFII28 PF04719.14 EJP62486.1 - 0.098 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region RNA_helicase PF00910.22 EJP62486.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PAP2 PF01569.21 EJP62487.1 - 2.6e-17 62.8 1.3 2.6e-17 62.8 1.3 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EJP62487.1 - 0.0025 17.6 1.5 0.0055 16.4 1.5 1.6 1 0 0 1 1 1 1 PAP2 superfamily TMPIT PF07851.13 EJP62487.1 - 4.7 6.4 6.5 9.9 5.3 6.5 1.5 1 0 0 1 1 1 0 TMPIT-like protein Cyt-b5 PF00173.28 EJP62488.1 - 1.6e-11 44.1 0.0 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cu_bind_like PF02298.17 EJP62489.1 - 0.00041 20.3 0.1 0.0011 18.9 0.1 1.7 1 1 0 1 1 1 1 Plastocyanin-like domain MGC-24 PF05283.11 EJP62489.1 - 0.18 12.3 1.5 0.27 11.7 1.5 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CENP-X PF09415.10 EJP62490.1 - 1.4e-23 82.9 0.4 2.7e-23 82.1 0.4 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X ASD2 PF08687.11 EJP62490.1 - 0.016 14.8 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 CBFD_NFYB_HMF PF00808.23 EJP62490.1 - 0.065 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.27 EJP62491.1 - 6e-66 218.4 3.8 1.1e-23 82.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 EJP62491.1 - 0.025 14.3 1.2 0.1 12.4 1.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Ribosomal_S25 PF03297.15 EJP62492.1 - 5.5e-38 129.2 5.1 6.1e-38 129.1 5.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 EJP62492.1 - 0.096 12.6 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 MarR family HTH_24 PF13412.6 EJP62492.1 - 0.14 11.7 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ribosomal_S7 PF00177.21 EJP62493.1 - 1.6e-37 128.5 1.6 1.9e-37 128.2 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_10 PF13673.7 EJP62494.1 - 3.5e-05 23.8 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP62494.1 - 0.00012 22.3 0.0 0.0014 18.9 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP62494.1 - 0.00059 20.2 0.0 0.0017 18.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EJP62494.1 - 0.02 15.6 0.2 0.55 11.0 0.2 2.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EJP62494.1 - 0.037 14.2 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DOCK_N PF16172.5 EJP62495.1 - 7.3e-120 400.3 0.0 1.6e-119 399.3 0.0 1.6 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 EJP62495.1 - 3.3e-35 121.7 4.4 1.1e-34 120.0 2.0 2.6 2 1 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 EJP62495.1 - 1.5e-34 119.6 0.0 2.6e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 EJP62495.1 - 1.2e-05 24.8 0.0 2.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP62495.1 - 0.00047 19.9 0.0 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EJP62495.1 - 0.0082 15.8 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_S8 PF00082.22 EJP62496.1 - 1.3e-29 103.4 7.4 2.2e-29 102.7 7.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJP62496.1 - 4e-07 30.6 0.0 7.4e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 ABC_membrane_2 PF06472.15 EJP62498.1 - 3e-103 344.9 1.3 4.6e-103 344.3 1.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EJP62498.1 - 1.1e-17 64.8 0.0 2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EJP62498.1 - 0.00014 21.8 0.0 0.00035 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RuvB_N PF05496.12 EJP62498.1 - 0.05 13.3 0.0 0.63 9.8 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 EJP62498.1 - 0.051 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP62498.1 - 0.063 13.7 0.1 0.5 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EJP62498.1 - 0.064 13.7 0.5 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EJP62498.1 - 0.094 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 EJP62498.1 - 0.1 12.0 0.1 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Guanylate_kin PF00625.21 EJP62499.1 - 2.8e-62 209.6 0.0 3.2e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EJP62499.1 - 0.00017 22.0 0.1 0.00044 20.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EJP62499.1 - 0.00022 21.4 0.1 0.0058 16.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EJP62499.1 - 0.00044 20.3 0.0 0.0025 17.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP62499.1 - 0.00052 20.0 0.0 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EJP62499.1 - 0.0015 19.1 0.1 0.0041 17.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJP62499.1 - 0.0087 16.3 0.0 0.021 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EJP62499.1 - 0.037 14.5 0.0 0.4 11.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 EJP62499.1 - 0.06 13.6 0.0 0.21 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain zf-CSL PF05207.13 EJP62500.1 - 5.5e-23 80.5 0.7 6.5e-23 80.2 0.7 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 EJP62500.1 - 0.0041 16.9 0.7 0.0068 16.2 0.7 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 EJP62500.1 - 0.0071 16.4 0.5 0.011 15.9 0.5 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Prok-RING_1 PF14446.6 EJP62500.1 - 0.39 10.7 2.2 0.72 9.8 2.2 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 tRNA-synt_1 PF00133.22 EJP62502.1 - 1.4e-34 119.3 0.2 2.7e-24 85.4 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EJP62502.1 - 2.2e-15 56.3 0.1 1.8e-08 33.5 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EJP62502.1 - 2.4e-11 43.8 3.6 3.3e-11 43.4 2.1 2.0 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EJP62502.1 - 1.7e-06 27.6 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Clat_adaptor_s PF01217.20 EJP62504.1 - 1.2e-43 148.5 0.0 2.7e-43 147.3 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.16 EJP62505.1 - 1.1e-36 125.2 0.0 1.4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Complex1_LYR_1 PF13232.6 EJP62506.1 - 0.044 14.4 0.3 0.076 13.6 0.2 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Complex1_LYR PF05347.15 EJP62506.1 - 0.056 13.5 0.4 0.056 13.5 0.4 2.0 2 1 0 2 2 2 0 Complex 1 protein (LYR family) SSP160 PF06933.11 EJP62506.1 - 3 5.9 5.1 3.7 5.6 5.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sugar_tr PF00083.24 EJP62507.1 - 3.4e-106 355.8 17.5 4.1e-106 355.5 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP62507.1 - 1.4e-25 89.9 49.9 8.8e-23 80.8 26.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EJP62507.1 - 5e-09 35.2 22.7 7.7e-06 24.7 8.1 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein WD40 PF00400.32 EJP62508.1 - 3.5e-42 141.6 18.5 1.8e-07 31.7 2.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP62508.1 - 7.2e-11 42.2 0.1 0.0013 19.0 0.0 4.8 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 EJP62508.1 - 1.6e-05 25.1 2.2 3.6e-05 24.0 2.2 1.6 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 EJP62508.1 - 0.0026 17.2 0.0 0.058 12.7 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EJP62508.1 - 0.0049 15.9 0.0 0.97 8.3 0.0 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MscS_porin PF12795.7 EJP62508.1 - 0.01 15.4 1.4 0.017 14.6 1.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain adh_short PF00106.25 EJP62509.1 - 2.5e-20 72.8 7.7 4.4e-16 58.9 7.7 3.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP62509.1 - 3.9e-20 72.4 9.9 1.4e-08 34.6 9.2 4.6 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EJP62509.1 - 6.4e-07 29.1 0.1 1.3e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EJP62509.1 - 3.2e-05 23.9 7.3 0.00022 21.2 7.3 2.2 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EJP62509.1 - 0.00015 21.7 1.4 0.00023 21.1 1.2 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 EJP62509.1 - 0.0018 17.9 0.3 0.0024 17.5 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family ApbA PF02558.16 EJP62509.1 - 0.0048 16.6 0.5 0.0097 15.6 0.4 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 EJP62509.1 - 0.011 15.1 0.4 0.02 14.2 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_2 PF07992.14 EJP62509.1 - 0.017 14.4 0.8 0.026 13.8 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP62509.1 - 0.027 15.0 0.7 0.049 14.2 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 EJP62509.1 - 0.032 13.6 0.0 0.072 12.5 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EJP62509.1 - 0.051 13.8 2.7 1.4 9.2 2.6 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF5631 PF18645.1 EJP62509.1 - 0.092 13.1 0.8 0.17 12.2 0.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5631) DAO PF01266.24 EJP62509.1 - 0.36 10.4 3.3 0.45 10.0 0.6 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.6 EJP62509.1 - 0.81 9.5 5.6 2.7 7.8 5.6 2.1 1 1 0 1 1 1 0 NAD(P)H-binding ThiF PF00899.21 EJP62510.1 - 4.7e-76 255.4 0.0 6.8e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EJP62510.1 - 9.3e-21 74.2 0.2 2.1e-20 73.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EJP62510.1 - 2.3e-07 31.0 0.9 2.2e-05 24.5 0.1 2.4 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EJP62510.1 - 0.0011 19.4 0.1 0.0034 17.8 0.1 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EJP62510.1 - 0.013 15.6 0.1 0.034 14.2 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EJP62510.1 - 0.041 14.2 0.3 0.19 12.0 0.3 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Q_salvage PF10343.9 EJP62511.1 - 1.8e-129 431.3 0.1 2.3e-129 430.9 0.1 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1563 PF07599.11 EJP62511.1 - 0.044 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) DNA_pol_delta_4 PF04081.13 EJP62512.1 - 6.8e-45 152.6 2.1 7.9e-45 152.4 1.5 1.3 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF3275 PF11679.8 EJP62512.1 - 0.05 13.6 2.0 0.066 13.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) WD40 PF00400.32 EJP62513.1 - 8.1e-23 80.3 14.2 2e-08 34.7 1.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP62513.1 - 2.9e-14 53.1 1.3 0.0017 18.6 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJP62513.1 - 8.6e-05 22.5 0.1 0.0046 16.9 0.0 3.1 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ribosomal_L32p PF01783.23 EJP62513.1 - 0.0003 21.0 1.2 0.0003 21.0 1.2 2.1 2 0 0 2 2 2 1 Ribosomal L32p protein family WD40_like PF17005.5 EJP62513.1 - 0.0022 17.4 0.0 0.0077 15.6 0.0 1.8 2 1 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EJP62513.1 - 0.014 14.3 0.1 3.9 6.3 0.0 3.2 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EJP62513.1 - 0.049 12.3 0.1 0.15 10.7 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 EJP62513.1 - 0.068 12.5 0.0 3.9 6.7 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EJP62513.1 - 0.14 10.9 0.0 0.44 9.2 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like ESX-1_EspG PF14011.6 EJP62513.1 - 0.14 11.7 0.0 0.4 10.3 0.0 1.8 1 1 0 1 1 1 0 EspG family Septin PF00735.18 EJP62514.1 - 1.2e-113 379.1 0.5 1.4e-113 378.9 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EJP62514.1 - 2e-07 31.1 0.0 3.6e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP62514.1 - 3.8e-06 26.9 0.1 0.00075 19.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EJP62514.1 - 5.4e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EJP62514.1 - 2.1e-05 24.2 0.4 0.012 15.2 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EJP62514.1 - 0.0014 18.7 0.2 1.6 8.8 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 EJP62514.1 - 0.0049 17.3 0.0 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.12 EJP62514.1 - 0.0051 16.2 0.1 0.21 10.9 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EJP62514.1 - 0.0077 16.5 0.0 0.017 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EJP62514.1 - 0.0078 15.4 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 EJP62514.1 - 0.01 16.4 0.4 0.017 15.6 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EJP62514.1 - 0.013 15.1 0.1 0.083 12.4 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region DUF1542 PF07564.11 EJP62514.1 - 0.032 14.3 0.1 0.091 12.9 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Microtub_bd PF16796.5 EJP62514.1 - 0.041 13.8 0.2 0.77 9.7 0.0 2.3 2 0 0 2 2 2 0 Microtubule binding FtsK_SpoIIIE PF01580.18 EJP62514.1 - 0.079 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 EJP62514.1 - 0.11 11.7 0.6 0.46 9.6 0.6 2.0 1 1 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 EJP62514.1 - 0.16 12.5 0.8 0.4 11.2 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJP62514.1 - 0.19 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_72 PF03198.14 EJP62516.1 - 1.1e-109 366.5 0.5 1.4e-109 366.2 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EJP62516.1 - 0.0059 16.1 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EJP62516.1 - 0.084 12.0 0.3 0.23 10.5 0.3 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain fn2 PF00040.19 EJP62516.1 - 0.66 10.3 4.1 1.8 8.9 4.1 1.7 1 0 0 1 1 1 0 Fibronectin type II domain LysM PF01476.20 EJP62518.1 - 4.6e-09 36.2 0.0 2e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 LysM domain CZB PF13682.6 EJP62518.1 - 0.89 10.0 3.0 8.6 6.9 3.0 2.2 1 1 0 1 1 1 0 Chemoreceptor zinc-binding domain AA_permease_2 PF13520.6 EJP62519.1 - 5.5e-83 279.2 42.1 5.5e-83 279.2 42.1 1.3 1 1 0 1 1 1 1 Amino acid permease FaeA PF04703.12 EJP62519.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 FaeA-like protein DUF4131 PF13567.6 EJP62519.1 - 6.4 6.4 14.9 0.6 9.7 0.4 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) EAP30 PF04157.16 EJP62521.1 - 0.85 8.9 4.3 1.4 8.2 4.3 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Citrate_bind PF16114.5 EJP62523.1 - 2.6e-86 287.7 0.0 3.5e-86 287.2 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EJP62523.1 - 7.3e-09 35.5 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 EJP62523.1 - 0.0019 16.4 0.0 0.0028 15.8 0.0 1.1 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 EJP62524.1 - 7.1e-21 74.7 0.0 9.3e-18 64.4 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EJP62524.1 - 6.3e-19 68.5 0.1 2.8e-18 66.4 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EJP62524.1 - 2.3e-16 60.0 0.1 4.6e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EJP62524.1 - 4e-06 26.7 0.0 0.00031 20.6 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Trypsin PF00089.26 EJP62527.1 - 7.8e-58 195.9 0.0 9.4e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP62527.1 - 1.5e-07 32.4 0.1 3.6e-07 31.2 0.1 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain ADH_zinc_N PF00107.26 EJP62528.1 - 4.5e-19 68.7 0.0 6.2e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EJP62528.1 - 2e-16 59.8 0.0 3.5e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EJP62528.1 - 9.1e-08 33.2 0.0 1.6e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DnaJ_C PF01556.18 EJP62529.1 - 3.4e-30 105.1 0.0 4.9e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJP62529.1 - 8.5e-26 89.9 1.2 1.5e-25 89.1 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EJP62529.1 - 1.9e-14 53.7 15.8 3.2e-14 53.0 15.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EJP62529.1 - 0.00022 21.2 7.3 0.066 13.2 0.8 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EJP62529.1 - 0.0059 16.5 8.2 0.35 10.9 2.0 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 EJP62529.1 - 0.045 13.4 7.9 0.062 13.0 0.2 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 SRR PF07709.11 EJP62529.1 - 0.075 13.4 0.1 11 6.9 0.0 2.9 2 0 0 2 2 2 0 Seven Residue Repeat Cytochrom_c3_2 PF14537.6 EJP62529.1 - 0.94 10.0 8.0 2 9.0 8.0 1.5 1 0 0 1 1 1 0 Cytochrome c3 zinc-ribbons_6 PF07191.12 EJP62529.1 - 1.1 9.3 10.5 25 4.9 10.5 2.2 1 1 0 1 1 1 0 zinc-ribbons zf-RING_10 PF16685.5 EJP62529.1 - 4.6 7.5 9.6 7 6.9 0.6 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 IF-2B PF01008.17 EJP62530.1 - 2.4e-50 171.3 0.0 3.2e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4646 PF15496.6 EJP62531.1 - 0.0045 17.6 1.9 0.22 12.2 1.9 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) APG6_N PF17675.1 EJP62531.1 - 0.028 15.0 4.4 0.065 13.8 4.4 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Peptidase_S49_N PF08496.10 EJP62531.1 - 6.1 6.9 7.3 13 5.8 7.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Acetyltransf_1 PF00583.25 EJP62532.1 - 1.7e-11 44.4 0.0 2.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP62532.1 - 1.5e-07 31.4 0.2 2.9e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP62532.1 - 1.3e-06 28.3 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EJP62532.1 - 7e-06 26.4 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP62532.1 - 0.019 15.1 0.1 0.032 14.3 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EJP62532.1 - 0.027 13.9 0.6 0.038 13.4 0.2 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase Yae1_N PF09811.9 EJP62533.1 - 7.3e-11 41.6 4.0 1.1e-10 41.0 4.0 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF4702 PF15774.5 EJP62533.1 - 0.035 13.1 0.1 0.043 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) AhpC-TSA PF00578.21 EJP62535.1 - 1.1e-23 83.5 0.0 1.5e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJP62535.1 - 7.6e-15 54.9 0.1 1.1e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EJP62535.1 - 0.13 12.4 0.0 1.6 8.9 0.0 2.1 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme RNA_pol_Rpc4 PF05132.14 EJP62535.1 - 0.15 12.5 6.2 0.31 11.5 6.2 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 EJP62535.1 - 1.1 9.5 5.2 1.8 8.7 5.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Mitofilin PF09731.9 EJP62535.1 - 1.4 7.7 10.9 1.6 7.4 10.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tim54 PF11711.8 EJP62535.1 - 2.9 6.6 6.9 3.9 6.1 6.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC27 PF09507.10 EJP62535.1 - 3.2 7.0 18.0 3.9 6.8 18.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 EJP62535.1 - 4.8 5.7 6.8 5.6 5.5 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Kazal_1 PF00050.21 EJP62536.1 - 0.0009 19.2 2.8 0.0009 19.2 2.8 1.3 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Mito_carr PF00153.27 EJP62537.1 - 1.6e-64 213.9 2.7 3.3e-22 78.2 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1304 PF06993.12 EJP62538.1 - 7.7e-42 141.7 1.7 8.8e-42 141.6 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) GDPD PF03009.17 EJP62539.1 - 2.2e-17 63.6 0.0 3.3e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family IF3_N PF05198.16 EJP62539.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain ABC_tran PF00005.27 EJP62540.1 - 5.5e-38 130.6 0.0 6.2e-18 65.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP62540.1 - 8.4e-31 107.6 28.9 5e-30 105.1 11.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP62540.1 - 1.6e-08 34.3 0.5 0.0086 15.5 0.1 3.8 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EJP62540.1 - 3.6e-06 27.5 2.4 0.015 15.7 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EJP62540.1 - 4.2e-05 23.5 1.2 0.0062 16.5 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EJP62540.1 - 9.7e-05 22.7 1.1 0.37 11.1 0.1 3.8 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 EJP62540.1 - 0.00027 20.3 0.3 0.0057 15.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 EJP62540.1 - 0.00032 20.8 1.0 0.28 11.3 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 EJP62540.1 - 0.00042 19.5 0.5 0.039 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein TsaE PF02367.17 EJP62540.1 - 0.0021 18.1 0.9 0.0051 16.8 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EJP62540.1 - 0.0034 16.9 0.2 0.59 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 EJP62540.1 - 0.006 16.7 1.3 2.4 8.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family TrwB_AAD_bind PF10412.9 EJP62540.1 - 0.0065 15.4 0.3 0.94 8.3 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 EJP62540.1 - 0.0068 16.3 0.7 0.93 9.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 EJP62540.1 - 0.0076 15.9 2.9 0.32 10.5 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EJP62540.1 - 0.0079 16.6 1.0 0.14 12.6 0.1 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EJP62540.1 - 0.019 15.2 0.9 0.63 10.3 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 EJP62540.1 - 0.033 13.4 0.4 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 EJP62540.1 - 0.037 13.8 2.2 1.2 9.0 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EJP62540.1 - 0.039 13.5 2.7 1.5 8.3 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EJP62540.1 - 0.049 13.4 1.0 4.4 7.0 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 EJP62540.1 - 0.05 13.4 8.3 2.4 7.9 0.1 4.1 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system PIF1 PF05970.14 EJP62540.1 - 0.11 11.6 1.1 0.46 9.6 0.2 2.3 3 0 0 3 3 3 0 PIF1-like helicase AAA_18 PF13238.6 EJP62540.1 - 0.12 12.9 0.2 5.4 7.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EJP62540.1 - 0.13 11.6 1.2 1.5 8.1 0.0 2.6 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain Roc PF08477.13 EJP62540.1 - 0.14 12.3 1.1 29 4.9 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EJP62540.1 - 0.15 12.5 0.2 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EJP62540.1 - 0.19 11.9 1.8 2.3 8.4 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EJP62540.1 - 0.2 10.8 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 EJP62540.1 - 0.21 11.6 4.1 0.69 10.0 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 EJP62540.1 - 0.26 11.0 0.7 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 EJP62540.1 - 0.29 11.6 0.2 36 4.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EJP62540.1 - 1.1 9.5 3.7 1.4 9.2 0.2 2.8 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EJP62540.1 - 1.3 9.0 3.2 34 4.4 0.1 3.3 3 1 1 4 4 3 0 AAA domain (dynein-related subfamily) UCR_14kD PF02271.16 EJP62541.1 - 3.4e-37 126.4 1.7 4.5e-36 122.8 1.7 1.9 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ferritin PF00210.24 EJP62541.1 - 0.049 13.5 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain ASL_C PF08328.11 EJP62541.1 - 0.14 12.3 0.8 1.7 8.8 0.2 2.0 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal UCH PF00443.29 EJP62542.1 - 4.7e-45 154.1 0.0 8.7e-45 153.2 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJP62542.1 - 1.4e-09 38.0 0.0 3.1e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NAM-associated PF14303.6 EJP62542.1 - 0.95 10.2 2.8 16 6.1 1.3 2.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SAE2 PF08573.10 EJP62543.1 - 4.7e-39 133.9 2.8 1.4e-38 132.4 0.5 2.8 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Filament PF00038.21 EJP62543.1 - 0.087 12.4 3.6 0.059 12.9 1.1 1.9 2 0 0 2 2 2 0 Intermediate filament protein HALZ PF02183.18 EJP62543.1 - 0.17 12.2 1.3 0.46 10.8 0.6 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2353 PF09789.9 EJP62543.1 - 0.37 10.1 4.9 0.64 9.3 0.4 2.4 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) zf-CCHC PF00098.23 EJP62544.1 - 6.1e-51 168.3 69.3 9.7e-09 34.9 4.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EJP62544.1 - 3.6e-11 42.6 43.5 0.022 14.5 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 EJP62544.1 - 5.7e-10 39.0 55.1 0.0014 18.5 1.6 7.1 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.6 EJP62544.1 - 4.9e-05 23.1 47.1 0.15 12.0 0.6 6.8 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 EJP62544.1 - 0.0068 16.2 12.4 0.012 15.5 2.3 6.7 7 0 0 7 7 7 4 Zinc knuckle zf-CCHC_5 PF14787.6 EJP62544.1 - 0.016 14.9 45.6 0.23 11.2 1.8 7.0 4 3 3 7 7 7 0 GAG-polyprotein viral zinc-finger Gla PF00594.20 EJP62544.1 - 0.16 12.2 2.7 26 5.1 0.4 3.4 3 0 0 3 3 3 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Acyl-CoA_dh_1 PF00441.24 EJP62545.1 - 1.5e-31 109.6 0.6 2.3e-31 109.0 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EJP62545.1 - 2e-19 69.5 0.0 4.7e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EJP62545.1 - 8.8e-17 61.1 0.1 1.6e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EJP62545.1 - 2.1e-08 34.8 0.0 5.4e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EJP62545.1 - 0.00071 19.9 0.1 0.0015 18.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain WD40 PF00400.32 EJP62546.1 - 7.5e-45 150.0 25.0 3.3e-08 34.0 0.1 10.7 10 0 0 10 10 10 9 WD domain, G-beta repeat NACHT_N PF17100.5 EJP62546.1 - 4e-44 151.1 1.3 3.1e-36 125.3 0.0 2.4 1 1 1 2 2 2 2 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 EJP62546.1 - 1e-24 86.6 0.5 0.007 16.6 0.1 9.0 4 2 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EJP62546.1 - 6.8e-14 52.1 0.1 1.5e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 EJP62546.1 - 4.5e-10 39.0 2.9 0.067 12.1 0.0 7.1 3 2 3 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EJP62546.1 - 2.1e-08 33.8 2.5 0.021 14.1 0.0 6.3 3 2 2 7 7 7 1 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.6 EJP62546.1 - 2.2e-07 31.4 0.0 1.2e-06 29.1 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.6 EJP62546.1 - 1e-05 25.3 4.7 0.03 13.9 0.1 3.5 1 1 2 3 3 3 2 PQQ-like domain PD40 PF07676.12 EJP62546.1 - 0.00013 21.8 0.1 45 4.1 0.0 6.9 9 0 0 9 9 8 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 EJP62546.1 - 0.0004 19.5 1.4 0.53 9.3 0.0 3.1 3 1 0 3 3 3 2 VID27 C-terminal WD40-like domain AAA_22 PF13401.6 EJP62546.1 - 0.0044 17.3 0.4 0.11 12.8 0.1 2.8 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 EJP62546.1 - 0.0066 16.5 0.0 0.02 14.9 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EJP62546.1 - 0.0086 16.4 0.0 0.045 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Gmad1 PF10647.9 EJP62546.1 - 0.014 15.1 2.0 2 8.1 0.1 3.9 3 1 1 4 4 4 0 Lipoprotein LpqB beta-propeller domain Peptidase_M4 PF01447.18 EJP62546.1 - 0.048 14.1 0.2 0.19 12.3 0.1 2.0 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain RNA_helicase PF00910.22 EJP62546.1 - 0.05 14.0 0.0 0.2 12.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EJP62546.1 - 0.066 13.2 0.2 0.51 10.4 0.2 2.5 1 1 0 1 1 1 0 AAA domain Nup160 PF11715.8 EJP62546.1 - 0.071 11.8 6.2 2.8 6.5 0.0 4.3 3 1 2 5 5 5 0 Nucleoporin Nup120/160 AAA PF00004.29 EJP62546.1 - 0.088 13.2 0.1 1.8 9.0 0.1 2.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GerE PF00196.19 EJP62547.1 - 3.7e-12 45.6 0.2 7.1e-12 44.7 0.1 1.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 EJP62547.1 - 1.1e-06 28.0 0.3 2e-06 27.2 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Response_reg PF00072.24 EJP62547.1 - 2.5e-06 27.7 0.1 4.6e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 EJP62547.1 - 7.3e-05 22.4 0.3 0.00012 21.6 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 EJP62547.1 - 0.0003 20.5 0.3 0.00054 19.7 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EJP62547.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Mga PF08280.11 EJP62547.1 - 0.089 12.8 0.3 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_20 PF12840.7 EJP62547.1 - 0.13 12.4 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ADH_zinc_N_2 PF13602.6 EJP62548.1 - 3.7e-22 79.8 0.0 8.5e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EJP62548.1 - 3.8e-13 49.6 0.0 8e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP62548.1 - 3.8e-06 26.7 0.0 1e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 EJP62548.1 - 1.8e-05 25.2 0.0 5.3e-05 23.7 0.0 1.8 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EJP62548.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP62548.1 - 0.023 14.6 0.1 0.069 13.0 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 EJP62548.1 - 0.031 13.4 0.1 0.057 12.5 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.20 EJP62548.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EJP62548.1 - 0.076 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family TOBE PF03459.17 EJP62548.1 - 0.14 12.5 1.6 2.3 8.6 0.1 3.0 3 0 0 3 3 3 0 TOBE domain Amino_oxidase PF01593.24 EJP62549.1 - 6.5e-56 190.5 0.0 1.2e-55 189.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP62549.1 - 8.5e-14 51.5 0.1 2.2e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EJP62549.1 - 4.1e-09 36.6 1.0 0.00013 21.9 0.1 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EJP62549.1 - 9.2e-06 25.1 0.0 7.3e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP62549.1 - 3.5e-05 22.7 0.1 0.00095 18.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EJP62549.1 - 3.6e-05 24.3 0.2 9.2e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP62549.1 - 0.0001 22.1 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP62549.1 - 0.00059 19.0 0.1 0.0013 17.9 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EJP62549.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EJP62549.1 - 0.0028 17.1 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EJP62549.1 - 0.0031 16.8 0.1 0.0053 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EJP62549.1 - 0.0037 16.6 0.2 0.012 14.9 0.0 1.7 1 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EJP62549.1 - 0.0053 16.7 0.1 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 EJP62549.1 - 0.0066 14.9 0.0 0.0099 14.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like GIDA PF01134.22 EJP62549.1 - 0.087 11.9 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Peptidase_A4 PF01828.17 EJP62551.1 - 4.6e-41 140.6 0.1 5.3e-41 140.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase A4 family Fumble PF03630.14 EJP62552.1 - 0.0087 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Fumble Peptidase_S8 PF00082.22 EJP62552.1 - 0.07 12.4 0.2 0.24 10.6 0.2 1.9 1 1 0 1 1 1 0 Subtilase family Astro_capsid_p PF12226.8 EJP62555.1 - 0.12 11.5 11.0 0.23 10.6 11.0 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2520 PF10728.9 EJP62555.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Pes-10 PF07149.11 EJP62555.1 - 0.32 10.0 4.3 0.59 9.1 4.3 1.4 1 0 0 1 1 1 0 Pes-10 DUF2457 PF10446.9 EJP62555.1 - 1.8 7.6 14.9 3.2 6.8 14.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NACHT_N PF17100.5 EJP62557.1 - 7e-11 42.4 0.0 1.3e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 EJP62557.1 - 4.9e-10 39.8 20.5 0.00034 21.3 0.4 7.7 7 0 0 7 7 7 3 WD domain, G-beta repeat PD40 PF07676.12 EJP62557.1 - 0.056 13.4 1.6 33 4.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cwf_Cwc_15 PF04889.12 EJP62557.1 - 2.4 7.8 10.6 7.8 6.1 10.6 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EJP62557.1 - 4.8 6.4 9.1 10 5.4 9.1 1.5 1 0 0 1 1 1 0 NOA36 protein M20_dimer PF07687.14 EJP62558.1 - 2.2e-09 37.2 0.1 8.1e-09 35.4 0.1 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EJP62558.1 - 9.3e-08 32.0 0.0 1.9e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Fungal_trans_2 PF11951.8 EJP62559.1 - 6.4e-12 45.0 0.4 1.8e-11 43.5 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP62559.1 - 2.1e-08 34.1 11.7 4e-08 33.2 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EJP62560.1 - 1.4e-32 113.0 34.9 1.4e-32 113.0 34.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily FMO-like PF00743.19 EJP62561.1 - 3e-21 75.4 0.4 1.1e-17 63.7 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EJP62561.1 - 1.2e-12 47.6 0.0 4.8e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP62561.1 - 1.3e-09 37.7 0.0 3.5e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP62561.1 - 1.1e-08 35.2 0.1 2.4e-06 27.7 0.1 2.9 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EJP62561.1 - 1.5e-08 34.2 0.0 1.4e-07 31.0 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EJP62561.1 - 5.4e-05 23.2 1.3 6.3 6.8 0.1 4.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EJP62561.1 - 0.00035 19.7 0.1 0.0039 16.3 0.1 2.5 3 1 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 EJP62561.1 - 0.00063 20.3 0.1 0.53 10.9 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP62561.1 - 0.00074 19.2 0.2 0.36 10.4 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EJP62561.1 - 0.0081 15.4 0.1 0.088 12.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EJP62561.1 - 0.034 12.9 1.0 0.28 9.9 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 EJP62561.1 - 0.075 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 EJP62562.1 - 2e-12 46.7 35.3 3e-09 36.3 34.1 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF5392 PF17370.2 EJP62562.1 - 0.0041 17.2 2.0 0.032 14.3 0.1 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF5392) OATP PF03137.20 EJP62562.1 - 0.02 13.2 9.8 0.39 8.9 0.2 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S28 PF05577.12 EJP62565.1 - 3.5e-48 164.5 0.0 9e-48 163.1 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 ATG2_CAD PF13329.6 EJP62566.1 - 2.6e-54 183.2 1.8 4.9e-54 182.3 1.8 1.5 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EJP62566.1 - 5.9e-28 97.1 4.0 2e-27 95.4 0.1 3.9 6 0 0 6 6 6 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EJP62566.1 - 5.4e-07 29.7 0.2 1.8e-05 24.8 0.1 3.0 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EJP62566.1 - 0.017 14.9 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Glyco_transf_8 PF01501.20 EJP62567.1 - 1.1e-12 48.0 0.0 2.4e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 zf-LITAF-like PF10601.9 EJP62568.1 - 9.2e-05 22.6 0.1 0.0002 21.6 0.1 1.6 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain K_channel_TID PF07941.11 EJP62568.1 - 0.02 15.3 6.0 0.027 14.9 1.2 3.0 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DUF4761 PF15958.5 EJP62569.1 - 1.5e-05 25.1 0.0 3.2 8.0 0.0 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF4761) DUF1659 PF07872.11 EJP62569.1 - 0.45 10.2 3.6 41 3.9 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1659) Zn_Tnp_IS1 PF03811.13 EJP62569.1 - 2 8.2 5.1 49 3.8 0.1 3.4 3 0 0 3 3 3 0 InsA N-terminal domain MFS_1 PF07690.16 EJP62571.1 - 1.1e-36 126.5 65.1 1e-21 77.3 36.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2371 PF10177.9 EJP62571.1 - 0.17 12.1 3.5 1.6 8.9 0.2 2.4 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF3824 PF12868.7 EJP62572.1 - 2.3e-06 28.3 11.3 2.3e-06 28.3 11.3 9.7 4 3 5 9 9 9 1 Domain of unknwon function (DUF3824) ABA_WDS PF02496.16 EJP62572.1 - 0.41 11.2 19.2 0.92 10.0 1.1 4.0 3 1 1 4 4 4 0 ABA/WDS induced protein DUF533 PF04391.12 EJP62572.1 - 3.3 7.2 13.9 0.16 11.5 1.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF533) COPIIcoated_ERV PF07970.12 EJP62573.1 - 1.8e-37 129.3 0.1 2.7e-37 128.8 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EJP62573.1 - 4.2e-24 84.7 0.0 7.5e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_C2 PF00648.21 EJP62574.1 - 1.4e-55 188.5 8.5 1.1e-37 129.7 0.3 2.9 3 1 0 3 3 3 2 Calpain family cysteine protease SUIM_assoc PF16619.5 EJP62574.1 - 7.6 6.7 20.3 1.8e+04 -5.2 20.3 3.0 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 COesterase PF00135.28 EJP62575.1 - 3.3e-56 191.2 0.0 6.3e-56 190.3 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EJP62575.1 - 1.3e-06 28.4 0.0 0.021 14.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sdh_cyt PF01127.22 EJP62576.1 - 2.8e-17 62.9 1.7 3.5e-17 62.6 1.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAF6_C PF07571.13 EJP62577.1 - 2e-25 88.9 0.0 4.4e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EJP62577.1 - 1.1e-21 76.7 0.3 1.9e-21 76.0 0.3 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EJP62577.1 - 0.041 14.2 0.2 0.07 13.5 0.2 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DJ-1_PfpI PF01965.24 EJP62578.1 - 5.2e-16 58.9 0.0 1.7e-15 57.2 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EJP62578.1 - 3.4e-06 26.9 0.0 6.3e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 EJP62578.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases Peptidase_C26 PF07722.13 EJP62578.1 - 0.062 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase C26 DUF2306 PF10067.9 EJP62579.1 - 1.2e-06 28.8 7.5 8.9e-06 26.0 7.5 2.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2306) Egh16-like PF11327.8 EJP62580.1 - 4.2e-45 154.4 7.8 4.2e-45 154.4 7.8 2.0 2 0 0 2 2 2 1 Egh16-like virulence factor Cu_bind_like PF02298.17 EJP62581.1 - 0.0044 17.0 0.2 0.013 15.5 0.2 1.8 2 1 0 2 2 2 1 Plastocyanin-like domain Acetyltransf_10 PF13673.7 EJP62582.1 - 2.2e-08 34.1 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP62582.1 - 1.2e-07 32.0 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP62582.1 - 1.9e-07 31.3 0.0 3.9e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EJP62582.1 - 0.0011 19.1 0.1 0.014 15.5 0.0 2.5 2 1 1 3 3 3 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EJP62582.1 - 0.074 13.1 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain T5orf172 PF10544.9 EJP62583.1 - 4.2e-23 81.8 1.6 8.3e-23 80.9 0.4 2.2 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 EJP62583.1 - 9.4e-18 64.7 1.9 1.3e-17 64.2 0.7 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 HNH_5 PF14279.6 EJP62583.1 - 0.064 13.1 2.2 7.6 6.5 0.0 3.1 3 0 0 3 3 3 0 HNH endonuclease zinc_ribbon_6 PF14599.6 EJP62583.1 - 0.12 12.5 3.0 3.8 7.6 0.6 2.9 2 0 0 2 2 2 0 Zinc-ribbon Glyco_transf_20 PF00982.21 EJP62584.1 - 3.8e-126 421.6 0.0 4.6e-126 421.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Spectrin PF00435.21 EJP62584.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Spectrin repeat XRCC1_N PF01834.16 EJP62584.1 - 0.088 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 XRCC1 N terminal domain Glyco_hydro_20 PF00728.22 EJP62586.1 - 3.4e-87 293.1 0.0 4.2e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EJP62586.1 - 6.3e-28 98.1 0.0 1.4e-27 97.0 0.0 1.6 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EJP62586.1 - 2.4e-06 28.4 0.1 0.00023 21.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Exo_endo_phos PF03372.23 EJP62587.1 - 3.4e-08 33.3 0.5 1.3e-07 31.4 0.5 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family He_PIG PF05345.12 EJP62587.1 - 0.067 13.4 0.3 1.9 8.8 0.1 2.7 3 0 0 3 3 3 0 Putative Ig domain Glyco_hydro_17 PF00332.18 EJP62588.1 - 5.5e-06 26.2 0.4 8.3e-06 25.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 NUDE_C PF04880.13 EJP62588.1 - 4.1 7.8 10.3 7.8 6.9 10.3 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF3846 PF12957.7 EJP62589.1 - 0.021 15.1 0.1 0.046 14.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) CMAS PF02353.20 EJP62590.1 - 7.6e-10 38.5 0.0 1.1e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EJP62590.1 - 4.3e-09 37.0 0.1 7.1e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP62590.1 - 3.1e-07 30.3 0.0 4.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP62590.1 - 6.7e-06 25.8 0.1 1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EJP62590.1 - 3.7e-05 24.4 0.0 5.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP62590.1 - 6.5e-05 23.5 0.0 0.0001 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP62590.1 - 0.00043 20.1 0.0 0.00073 19.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EJP62590.1 - 0.00063 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EJP62590.1 - 0.0075 15.9 0.1 0.017 14.7 0.1 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PrmA PF06325.13 EJP62590.1 - 0.0085 15.5 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 EJP62590.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 EJP62590.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 EJP62590.1 - 0.061 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EJP62590.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 EJP62590.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sulfatase PF00884.23 EJP62594.1 - 6e-18 65.3 0.3 3.6e-17 62.7 0.1 2.1 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 EJP62594.1 - 0.00016 21.4 0.2 0.00045 19.9 0.1 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EJP62594.1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily MatE PF01554.18 EJP62595.1 - 6.6e-52 175.4 29.5 5.3e-34 117.2 8.6 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EJP62595.1 - 3.2e-05 24.0 17.1 3.2e-05 24.0 17.1 3.5 2 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain WD40 PF00400.32 EJP62596.1 - 4.9e-15 55.7 15.5 0.0018 19.1 0.2 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 EJP62596.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.6 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 EJP62596.1 - 0.0012 17.9 0.5 0.019 14.0 0.0 2.6 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EJP62596.1 - 0.0035 17.6 0.0 1.7 9.0 0.0 4.2 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain AA_permease PF00324.21 EJP62598.1 - 9.4e-135 449.9 33.5 1.2e-134 449.6 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP62598.1 - 2.9e-35 121.9 32.6 3.7e-35 121.6 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 EJP62599.1 - 2.6e-05 24.2 2.2 4.9e-05 23.4 2.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP62599.1 - 0.00014 20.8 0.6 0.00019 20.3 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CortBP2 PF09727.9 EJP62599.1 - 0.031 14.2 0.1 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 Cortactin-binding protein-2 adh_short PF00106.25 EJP62600.1 - 1.5e-41 142.0 0.1 2.1e-41 141.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP62600.1 - 3.6e-29 102.0 0.1 5.5e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP62600.1 - 2.1e-11 44.0 1.2 1.5e-10 41.3 1.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP62600.1 - 3.9e-05 23.2 0.0 0.00023 20.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP62600.1 - 0.0008 19.3 0.2 0.0019 18.1 0.0 1.8 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EJP62600.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UPF0146 PF03686.13 EJP62600.1 - 0.0018 18.2 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0146) DUF1776 PF08643.10 EJP62600.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Alpha_L_fucos PF01120.17 EJP62601.1 - 1.2e-26 94.1 0.0 3.4e-26 92.5 0.0 1.5 1 1 0 2 2 2 1 Alpha-L-fucosidase adh_short_C2 PF13561.6 EJP62602.1 - 3.5e-38 131.5 0.5 4.1e-38 131.2 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP62602.1 - 3.2e-35 121.4 0.1 3.8e-35 121.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP62602.1 - 7.8e-08 32.4 0.1 1.2e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP62602.1 - 1.9e-06 27.5 0.3 3.5e-05 23.4 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EJP62602.1 - 0.061 12.6 0.5 0.096 12.0 0.5 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 EJP62603.1 - 2e-08 34.0 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EJP62603.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP62603.1 - 0.022 14.0 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 EJP62603.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EJP62603.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 EJP62603.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Endotoxin_N PF03945.14 EJP62605.1 - 3.2e-17 63.0 0.0 6.6e-15 55.4 0.0 2.6 2 1 1 3 3 3 2 delta endotoxin, N-terminal domain Jacalin PF01419.17 EJP62605.1 - 2.8e-06 27.3 0.0 7.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF1932 PF09130.11 EJP62605.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) 2-Hacid_dh_C PF02826.19 EJP62607.1 - 3.7e-54 182.8 0.0 6.7e-54 181.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJP62607.1 - 7.2e-35 119.6 0.1 1.4e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EJP62607.1 - 1.7e-05 24.5 2.0 0.0023 17.7 0.1 3.1 3 0 0 3 3 3 2 ACT domain XdhC_C PF13478.6 EJP62607.1 - 0.017 15.6 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Glyoxalase PF00903.25 EJP62608.1 - 5.4e-43 146.2 0.4 1.7e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EJP62608.1 - 9.6e-19 67.7 0.1 9.1e-08 32.4 0.0 4.5 2 2 2 4 4 4 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EJP62608.1 - 8.3e-09 36.2 0.0 0.00059 20.6 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EJP62608.1 - 1e-06 28.7 1.9 0.0037 17.2 0.1 4.2 2 2 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EJP62608.1 - 3.3e-06 27.3 0.0 0.05 13.7 0.0 3.6 1 1 2 3 3 3 3 Glyoxalase-like domain DUF1338 PF07063.13 EJP62608.1 - 0.0024 17.1 0.0 10 5.2 0.0 3.4 4 0 0 4 4 4 2 Domain of unknown function (DUF1338) CppA_N PF14506.6 EJP62608.1 - 0.0089 16.1 0.1 0.31 11.1 0.0 2.3 2 0 0 2 2 2 1 CppA N-terminal Pfk_N PF18468.1 EJP62608.1 - 0.02 15.3 0.1 4 7.9 0.0 2.5 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast MoaF PF10703.9 EJP62608.1 - 0.05 13.5 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 MoaF N-terminal domain HTH_54 PF18607.1 EJP62608.1 - 0.078 13.0 0.0 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 ParA helix turn helix domain DUF3246 PF11596.8 EJP62609.1 - 0.017 14.6 1.5 0.029 13.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 EJP62610.1 - 0.0087 16.4 3.4 0.015 15.6 3.4 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain NOA36 PF06524.12 EJP62610.1 - 1.4 8.2 3.3 2 7.7 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 EJP62611.1 - 2.3e-44 151.8 40.4 2.3e-44 151.8 40.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EJP62611.1 - 3.4e-11 43.0 6.6 3.4e-11 43.0 6.6 3.0 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EJP62611.1 - 9.5e-07 28.0 29.5 1.6e-05 24.0 29.5 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter TPPK_C PF12555.8 EJP62611.1 - 0.16 12.0 3.8 3.6 7.7 0.1 3.4 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Fungal_trans PF04082.18 EJP62612.1 - 1.4e-13 50.5 0.1 2.7e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_5 PF14696.6 EJP62613.1 - 0.021 15.0 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF1690 PF07956.11 EJP62613.1 - 0.042 14.3 1.3 0.11 12.9 1.3 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Pkinase PF00069.25 EJP62614.1 - 1.8e-14 53.8 0.0 5.2e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62614.1 - 0.00099 18.5 0.0 0.29 10.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Peptidase_M10 PF00413.24 EJP62615.1 - 9.7e-05 22.3 0.2 0.00017 21.5 0.2 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 EJP62615.1 - 0.00028 20.6 0.0 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EJP62615.1 - 0.0012 19.3 0.1 0.0022 18.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EJP62615.1 - 0.0015 18.5 0.3 0.0021 18.0 0.3 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EJP62615.1 - 0.0068 16.6 0.7 0.0099 16.0 0.7 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Metallopep PF12044.8 EJP62615.1 - 0.013 14.1 0.1 0.021 13.5 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M43 PF05572.13 EJP62615.1 - 0.024 14.6 1.6 0.43 10.5 1.6 2.4 1 1 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M54 PF07998.11 EJP62615.1 - 0.16 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M54 Zincin_1 PF06262.11 EJP62615.1 - 0.17 12.0 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase DER1 PF04511.15 EJP62616.1 - 5.1e-52 176.6 4.6 5.7e-52 176.4 4.6 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.14 EJP62617.1 - 7.6e-47 159.4 0.1 9.3e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EJP62617.1 - 2.3e-07 30.4 0.2 3.6e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EJP62617.1 - 1.5e-05 24.9 0.4 2.2e-05 24.4 0.4 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain adh_short PF00106.25 EJP62618.1 - 1.2e-29 103.2 0.0 1.6e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP62618.1 - 1.9e-19 70.2 0.0 2.7e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP62618.1 - 5.7e-10 39.4 0.0 8.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP62618.1 - 8.4e-07 28.7 0.1 1.6e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP62618.1 - 0.0026 17.2 0.0 0.0056 16.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EJP62618.1 - 0.004 16.3 0.0 0.0097 15.0 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EJP62618.1 - 0.0048 16.1 0.0 0.0063 15.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EJP62618.1 - 0.0086 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EJP62618.1 - 0.018 14.0 0.1 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Catalase-rel PF06628.12 EJP62618.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive NmrA PF05368.13 EJP62618.1 - 0.24 10.9 0.0 0.88 9.1 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family MBOAT PF03062.19 EJP62619.1 - 1.4e-54 185.8 3.2 1.6e-54 185.6 1.7 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.21 EJP62619.1 - 0.74 9.6 9.2 0.11 12.3 4.3 2.1 2 0 0 2 2 2 0 PAP2 superfamily CPBP PF02517.16 EJP62621.1 - 2.2e-14 53.6 14.9 9.5e-14 51.5 12.6 2.7 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease MMM1 PF10296.9 EJP62622.1 - 2.4e-138 460.7 0.1 9.4e-137 455.5 0.1 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Pilin_N PF07790.11 EJP62622.1 - 0.044 14.7 0.0 0.091 13.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Sec1 PF00995.23 EJP62623.1 - 2.4e-120 403.5 7.3 1.3e-118 397.8 7.3 2.0 1 1 0 1 1 1 1 Sec1 family CLU PF13236.6 EJP62624.1 - 9.4e-76 254.5 0.0 1.6e-75 253.8 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EJP62624.1 - 1e-52 178.7 0.0 2.1e-52 177.7 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EJP62624.1 - 1.7e-25 89.1 4.5 4.4e-11 42.9 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 EJP62624.1 - 5e-22 78.0 0.0 1.9e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 EJP62624.1 - 1e-21 76.1 0.3 1e-06 28.4 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EJP62624.1 - 2.4e-05 24.2 5.8 0.0031 17.6 0.2 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EJP62624.1 - 2.8e-05 23.9 0.5 0.072 13.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF727 PF05303.12 EJP62624.1 - 0.0006 19.9 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_1 PF00515.28 EJP62624.1 - 0.15 11.9 0.1 5.9 6.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EJP62624.1 - 0.44 11.0 3.1 64 4.3 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Forkhead PF00250.18 EJP62625.1 - 1.2e-34 118.4 0.5 2.2e-34 117.6 0.5 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EJP62625.1 - 6.9e-10 39.1 0.0 2.3e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EJP62625.1 - 0.00017 21.8 0.0 0.00047 20.4 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain PAP_central PF04928.17 EJP62626.1 - 2.2e-110 367.5 0.0 2.9e-110 367.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EJP62626.1 - 3.5e-64 215.5 0.9 5.9e-64 214.8 0.9 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EJP62626.1 - 5.2e-10 39.5 0.1 1.2e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EJP62626.1 - 0.033 14.3 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 EJP62626.1 - 0.073 12.8 0.1 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain DUF3391 PF11871.8 EJP62626.1 - 0.66 10.5 3.5 0.75 10.3 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) Tubulin_3 PF14881.6 EJP62627.1 - 4.9e-77 257.7 0.4 2.6e-75 252.1 0.1 2.3 2 0 0 2 2 2 2 Tubulin domain Misat_Tub_SegII PF10644.9 EJP62627.1 - 2.5e-38 131.0 0.0 4.6e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EJP62627.1 - 4.5e-06 27.0 0.0 0.00016 22.0 0.0 2.2 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain AhpC-TSA_2 PF13911.6 EJP62628.1 - 3.9e-06 27.0 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EJP62628.1 - 0.0001 22.2 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Septin PF00735.18 EJP62629.1 - 2.5e-12 46.7 0.0 2.6e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Septin AAA PF00004.29 EJP62629.1 - 0.00076 19.9 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJP62629.1 - 0.0061 17.0 0.2 0.014 15.8 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EJP62629.1 - 0.0087 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP62629.1 - 0.037 14.6 0.0 0.08 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJP62629.1 - 0.042 14.4 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EJP62629.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EJP62629.1 - 0.14 12.1 0.0 0.8 9.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EJP62629.1 - 0.16 11.7 0.1 0.35 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 EJP62630.1 - 1.1e-76 257.8 0.0 1.2e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62630.1 - 2.1e-36 125.6 0.0 2.7e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJP62630.1 - 0.013 14.4 0.0 0.08 11.9 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EJP62630.1 - 0.019 14.3 0.1 0.05 12.9 0.0 1.7 1 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 EJP62630.1 - 0.023 14.1 0.2 0.039 13.3 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.21 EJP62631.1 - 2.6e-13 49.8 0.0 3.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase zf-RING_UBOX PF13445.6 EJP62632.1 - 2.2e-09 37.2 7.4 1.2e-05 25.2 3.0 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 EJP62632.1 - 1.3e-07 31.6 0.0 8.3e-07 29.1 0.0 2.3 3 0 0 3 3 3 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_4 PF15227.6 EJP62632.1 - 1.5e-07 31.5 11.0 0.0004 20.5 3.4 2.7 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EJP62632.1 - 2.4e-05 24.2 4.6 2.4e-05 24.2 4.6 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EJP62632.1 - 4.5e-05 23.2 9.9 0.04 13.8 2.3 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP62632.1 - 6.6e-05 22.7 14.0 0.026 14.4 6.1 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP62632.1 - 8.2e-05 22.9 12.6 0.02 15.2 5.9 2.9 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 EJP62632.1 - 0.00019 21.2 12.2 0.0046 16.8 4.9 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EJP62632.1 - 0.073 13.2 11.8 0.15 12.2 4.0 3.3 2 1 1 3 3 3 0 FYVE zinc finger zf-AD PF07776.15 EJP62632.1 - 0.44 10.8 0.0 0.44 10.8 0.0 2.9 3 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) IBR PF01485.21 EJP62632.1 - 3.1 8.1 9.0 1.1 9.5 0.7 3.0 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DZR PF12773.7 EJP62632.1 - 7.2 6.7 14.4 7.7 6.6 5.8 3.4 2 1 0 2 2 2 0 Double zinc ribbon Mito_carr PF00153.27 EJP62633.1 - 2.8e-46 155.4 0.3 2.5e-18 65.8 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein SCA7 PF08313.12 EJP62634.1 - 3e-32 110.3 0.1 1.1e-31 108.6 0.1 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.14 EJP62634.1 - 0.021 13.1 13.8 0.03 12.7 13.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Omega-toxin PF06357.11 EJP62634.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Omega-atracotoxin DUF2052 PF09747.9 EJP62634.1 - 1 9.4 17.5 1.5 8.9 15.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) eIF-3c_N PF05470.12 EJP62634.1 - 4.7 5.4 20.5 8.5 4.6 20.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3537 PF12056.8 EJP62634.1 - 6.2 5.5 4.7 9.2 5.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) SAPS PF04499.15 EJP62634.1 - 7.7 5.2 7.5 11 4.7 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM176 PF14851.6 EJP62634.1 - 8.1 6.1 12.6 35 4.0 10.6 2.5 2 0 0 2 2 2 0 FAM176 family Lipase_GDSL_2 PF13472.6 EJP62635.1 - 1.3e-09 38.7 0.0 2.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EJP62635.1 - 0.013 15.4 0.1 0.051 13.5 0.1 2.0 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Kinesin PF00225.23 EJP62637.1 - 2.7e-105 352.0 0.4 2.7e-105 352.0 0.4 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EJP62637.1 - 1.7e-54 183.8 0.0 4.3e-54 182.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HTH_Tnp_Tc3_2 PF01498.18 EJP62637.1 - 4.6e-06 26.8 2.4 8.1e-06 26.0 0.2 2.6 2 0 0 2 2 2 1 Transposase WEMBL PF05701.11 EJP62637.1 - 4.4e-05 22.4 32.7 4.4e-05 22.4 32.7 1.9 2 0 0 2 2 2 1 Weak chloroplast movement under blue light DDE_3 PF13358.6 EJP62637.1 - 4.5e-05 23.2 0.8 0.00013 21.8 0.1 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease CENP-F_leu_zip PF10473.9 EJP62637.1 - 0.0036 17.3 41.9 0.029 14.4 17.9 3.4 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 PF13191.6 EJP62637.1 - 0.43 10.9 0.0 0.43 10.9 0.0 3.3 2 1 0 2 2 1 0 AAA ATPase domain Uso1_p115_C PF04871.13 EJP62637.1 - 1.3 9.4 40.9 1.5 9.2 4.7 4.6 4 1 1 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 EJP62637.1 - 1.8 8.6 14.4 2.6 8.1 1.4 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 EJP62637.1 - 2.9 7.2 28.3 2.1 7.7 13.9 3.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) OmpH PF03938.14 EJP62637.1 - 4.5 7.6 35.3 0.13 12.6 1.5 3.4 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 EJP62638.1 - 5.7e-08 32.7 8.6 1.1e-07 31.9 8.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EJP62638.1 - 2.4e-07 30.7 7.9 5.1e-07 29.7 7.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EJP62638.1 - 0.0054 17.2 5.1 0.0054 17.2 5.1 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor Takusan PF04822.13 EJP62638.1 - 1.2 9.1 4.0 0.92 9.4 1.8 2.0 2 0 0 2 2 2 0 Takusan FAD_binding_4 PF01565.23 EJP62640.1 - 1.6e-28 99.2 2.5 1.6e-28 99.2 2.5 1.7 2 0 0 2 2 2 1 FAD binding domain Period_C PF12114.8 EJP62642.1 - 0.0046 16.6 5.2 0.0046 16.6 5.2 1.9 2 0 0 2 2 2 1 Period protein 2/3C-terminal region MRP-S31 PF15433.6 EJP62642.1 - 0.18 11.4 4.0 0.22 11.1 4.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 SR-25 PF10500.9 EJP62642.1 - 2.6 7.6 21.8 0.016 14.8 9.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sec62 PF03839.16 EJP62642.1 - 3.6 7.0 4.8 4.6 6.7 4.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.14 EJP62642.1 - 4.1 5.6 8.6 4.8 5.3 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 EJP62642.1 - 5.9 4.9 7.1 6.5 4.8 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 EJP62642.1 - 8.2 5.1 8.1 9.8 4.8 8.1 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_S13 PF00416.22 EJP62643.1 - 3e-56 189.3 2.8 3.5e-56 189.1 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EJP62643.1 - 0.019 13.7 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SBDS_C PF09377.10 EJP62644.1 - 3.6e-45 152.7 0.1 6.3e-45 151.9 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EJP62644.1 - 5.8e-36 122.4 0.4 1.1e-35 121.6 0.4 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein tRNA-synt_1b PF00579.25 EJP62645.1 - 2.1e-18 66.7 0.0 3.3e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Peptidase_S10 PF00450.22 EJP62646.1 - 1.6e-125 419.9 0.2 1.9e-125 419.6 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EJP62646.1 - 4.2e-13 49.9 0.2 1.8e-12 47.9 0.2 2.0 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide Trypan_PARP PF05887.11 EJP62647.1 - 0.0027 17.7 15.6 0.086 12.8 10.8 2.2 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) ELO PF01151.18 EJP62648.1 - 3.1e-81 272.6 6.8 4.1e-81 272.2 6.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family FYVE PF01363.21 EJP62649.1 - 1.1e-16 60.8 6.9 1.7e-16 60.1 6.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EJP62649.1 - 9.2 6.5 13.6 2.4 8.4 8.6 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger Amidohydro_3 PF07969.11 EJP62650.1 - 5.1e-82 276.8 11.3 6.3e-82 276.5 11.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EJP62650.1 - 3.3e-16 59.5 0.1 1.1e-11 44.6 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family PIG-X PF08320.12 EJP62650.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 PIG-X / PBN1 HMGL-like PF00682.19 EJP62651.1 - 4e-63 213.4 0.0 1.1e-62 212.1 0.0 1.6 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 EJP62651.1 - 4e-22 78.5 0.0 1.1e-21 77.2 0.0 1.7 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain HNH_repeat PF18780.1 EJP62651.1 - 2.9 7.8 4.7 0.56 10.1 0.2 2.1 2 0 0 2 2 2 0 Homing endonuclease repeat EamA PF00892.20 EJP62652.1 - 5.3e-18 65.5 33.5 3.3e-12 46.8 11.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family Acetyltransf_7 PF13508.7 EJP62653.1 - 4.5e-06 27.0 0.0 5.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP62653.1 - 6e-06 26.5 0.0 7.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP62653.1 - 0.0002 21.3 0.0 0.0004 20.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP62653.1 - 0.0018 18.2 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 EJP62653.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase Fungal_trans_2 PF11951.8 EJP62654.1 - 4.8e-07 28.9 0.1 6.3e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EJP62654.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.25 EJP62655.1 - 3.6e-37 127.7 0.1 4.6e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP62655.1 - 2e-20 73.4 0.0 2.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP62655.1 - 1.1e-08 35.2 0.1 1.6e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EJP62655.1 - 0.0002 21.6 0.4 0.00065 20.0 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EJP62655.1 - 0.00027 20.5 0.4 0.00094 18.7 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP62655.1 - 0.0018 18.2 0.1 0.0027 17.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EJP62655.1 - 0.0081 15.6 0.1 0.061 12.7 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EJP62655.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EJP62655.1 - 0.04 14.5 0.2 0.16 12.6 0.1 1.9 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EJP62655.1 - 0.045 13.4 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Psu PF07455.11 EJP62655.1 - 0.06 12.9 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) TrkA_N PF02254.18 EJP62655.1 - 0.064 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 EJP62655.1 - 0.13 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Bac_globin PF01152.21 EJP62656.1 - 0.0077 16.4 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial-like globin MGC-24 PF05283.11 EJP62656.1 - 0.15 12.5 8.9 0.036 14.5 5.7 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin BTB PF00651.31 EJP62658.1 - 1.6e-08 34.8 0.0 5.6e-08 33.0 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain BacteriocIIc_cy PF12173.8 EJP62658.1 - 0.052 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like Glyoxalase_3 PF13468.6 EJP62659.1 - 4.2e-20 72.6 0.0 5.4e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain APH PF01636.23 EJP62660.1 - 7.9e-18 65.3 0.0 1.1e-17 64.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP62660.1 - 0.00047 19.8 0.0 0.00074 19.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EJP62660.1 - 0.0039 16.8 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family CFEM PF05730.11 EJP62661.1 - 1.5e-16 60.2 19.1 9e-09 35.3 7.6 2.6 2 0 0 2 2 2 2 CFEM domain 4HBT PF03061.22 EJP62662.1 - 4e-12 46.3 1.9 6.8e-12 45.6 1.4 1.7 1 1 1 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 EJP62662.1 - 0.0012 19.0 0.1 0.0024 18.0 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 EJP62662.1 - 0.0022 18.3 0.5 0.0033 17.7 0.3 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily Fungal_trans PF04082.18 EJP62663.1 - 3.8e-13 49.1 0.8 3.1e-08 33.0 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP62663.1 - 2.1e-08 34.2 7.2 4.8e-08 33.0 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fanconi_A PF03511.14 EJP62663.1 - 0.067 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Fanconi anaemia group A protein Ldh_2 PF02615.14 EJP62664.1 - 1.4e-125 418.9 0.8 1.6e-125 418.7 0.8 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Transp_cyt_pur PF02133.15 EJP62665.1 - 3.1e-152 507.4 41.2 3.6e-152 507.2 41.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NicO PF03824.16 EJP62666.1 - 2.3e-57 194.5 6.2 2.8e-57 194.2 6.2 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF3318 PF11780.8 EJP62666.1 - 0.029 14.3 0.7 0.072 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) FlgM PF04316.13 EJP62667.1 - 0.12 12.8 2.7 12 6.3 0.1 2.9 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM APG17 PF04108.12 EJP62668.1 - 3.8e-128 428.0 8.1 4.3e-128 427.8 8.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 ACT_4 PF13291.6 EJP62668.1 - 0.038 14.6 0.7 0.41 11.3 0.4 2.5 2 0 0 2 2 2 0 ACT domain CBAH PF02275.18 EJP62668.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Bacillus_HBL PF05791.11 EJP62668.1 - 0.72 9.6 4.8 0.56 10.0 1.1 2.5 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) MoaC PF01967.21 EJP62669.1 - 3.3e-52 176.2 3.3 6.7e-52 175.2 3.3 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EJP62669.1 - 1.7e-36 125.0 0.0 1.1e-35 122.3 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EJP62669.1 - 1.7e-25 90.4 0.0 4.6e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EJP62669.1 - 3.5e-05 24.1 0.0 0.00012 22.4 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fungal_trans PF04082.18 EJP62670.1 - 1.6e-06 27.4 0.2 2.8e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP62670.1 - 5.1e-06 26.5 9.5 9.5e-06 25.6 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPP_enzyme_N PF02776.18 EJP62671.1 - 8e-34 116.7 0.0 1.3e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EJP62671.1 - 1.9e-21 76.4 0.1 4.4e-19 68.8 0.0 2.6 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJP62671.1 - 8.3e-16 58.0 0.0 2.1e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Aminotran_1_2 PF00155.21 EJP62672.1 - 6.1e-17 61.8 0.0 7.8e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EJP62672.1 - 9.1e-05 21.4 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cyclin PF08613.11 EJP62674.1 - 4.1e-44 150.8 0.0 7.8e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin SSP160 PF06933.11 EJP62675.1 - 0.0083 14.4 7.1 0.011 14.0 7.1 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 TPPII_N PF12583.8 EJP62675.1 - 0.11 13.1 1.2 0.19 12.3 1.2 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Dicty_REP PF05086.12 EJP62675.1 - 1.4 6.9 2.6 1.6 6.6 2.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TPP_enzyme_N PF02776.18 EJP62676.1 - 4.4e-29 101.3 0.3 6.3e-27 94.3 0.5 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EJP62676.1 - 1.1e-16 61.0 0.1 2.9e-16 59.6 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJP62676.1 - 5.4e-10 39.1 0.0 1.3e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain FAD_binding_3 PF01494.19 EJP62677.1 - 2.1e-16 60.1 0.5 3.6e-08 33.1 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EJP62677.1 - 0.00012 22.3 0.0 0.00044 20.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP62677.1 - 0.0035 17.0 0.4 0.14 11.7 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP62677.1 - 0.039 14.5 0.0 0.2 12.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EJP62677.1 - 0.13 11.3 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_4 PF01565.23 EJP62678.1 - 2.6e-27 95.3 0.8 4.5e-27 94.5 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP62678.1 - 7.2e-14 51.6 0.6 1.5e-13 50.6 0.6 1.5 1 0 0 1 1 1 1 Berberine and berberine like UDPG_MGDP_dh PF00984.19 EJP62679.1 - 4.4e-19 68.5 0.0 1.2e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 EJP62679.1 - 1.1e-16 60.9 0.3 1.6e-14 53.9 0.3 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 EJP62679.1 - 2.9e-05 24.3 0.0 4.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PALP PF00291.25 EJP62679.1 - 0.039 13.4 0.4 0.12 11.8 0.3 1.7 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 EJP62679.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EJP62679.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Polysacc_deac_1 PF01522.21 EJP62680.1 - 2.1e-26 92.2 0.0 3.6e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EJP62680.1 - 6.6e-05 23.3 21.9 0.00025 21.5 21.9 2.0 1 1 0 1 1 1 1 Chitin recognition protein DUF2334 PF10096.9 EJP62680.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Chitin_synth_2 PF03142.15 EJP62681.1 - 9.7e-39 133.4 1.6 1.7e-29 102.8 0.9 2.3 2 1 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 EJP62681.1 - 3e-10 40.2 0.0 0.00026 20.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EJP62681.1 - 2.2e-05 24.5 8.8 2.2e-05 24.5 8.8 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EJP62681.1 - 0.0055 16.6 2.6 6.4 6.6 2.6 3.0 2 1 0 2 2 2 2 Glycosyltransferase like family 2 PALP PF00291.25 EJP62682.1 - 2e-68 230.9 0.2 2.9e-68 230.4 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EJP62682.1 - 1.5e-10 41.4 0.0 4.2e-08 33.5 0.0 2.8 3 0 0 3 3 3 2 CBS domain SRPRB PF09439.10 EJP62683.1 - 6.5e-25 87.6 0.0 4.3e-24 84.9 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EJP62683.1 - 6.3e-05 22.6 0.0 0.00014 21.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EJP62683.1 - 0.00085 19.4 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EJP62683.1 - 0.0024 17.3 0.1 0.02 14.4 0.1 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJP62683.1 - 0.066 12.6 0.0 0.3 10.4 0.0 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.14 EJP62683.1 - 0.067 13.2 0.2 0.16 11.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EJP62683.1 - 0.075 12.6 0.6 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EJP62683.1 - 0.087 13.2 1.0 0.19 12.1 1.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EJP62683.1 - 0.11 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Septin DHHC PF01529.20 EJP62685.1 - 1.9e-32 112.2 12.9 1.9e-32 112.2 12.9 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EJP62685.1 - 3e-27 95.0 0.0 1e-13 51.7 0.0 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP62685.1 - 1.3e-25 89.4 0.5 2.9e-07 30.9 0.2 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP62685.1 - 1.7e-23 82.4 0.4 8.5e-06 25.9 0.0 5.6 3 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP62685.1 - 1e-20 71.6 1.7 5.1e-07 29.5 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EJP62685.1 - 1e-20 73.2 0.5 1.5e-05 25.2 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Nucleoporin_FG2 PF15967.5 EJP62685.1 - 0.024 13.2 0.6 0.039 12.5 0.6 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region PocR PF10114.9 EJP62685.1 - 1.2 8.9 4.0 2.5 7.9 4.0 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR Pyr_redox_3 PF13738.6 EJP62687.1 - 1.4e-14 54.0 0.1 3.1e-12 46.4 0.5 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP62687.1 - 1.4e-10 40.9 0.0 2.3e-08 33.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EJP62687.1 - 7.1e-09 34.6 0.1 8.5e-08 31.1 0.1 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EJP62687.1 - 8.4e-09 35.0 0.0 1.7e-05 24.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EJP62687.1 - 9.9e-07 28.9 0.1 9.9e-07 28.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP62687.1 - 4.5e-06 26.5 0.9 1.7e-05 24.6 0.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP62687.1 - 1.1e-05 25.9 1.3 0.045 14.3 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP62687.1 - 0.00085 18.5 0.4 0.0016 17.6 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 EJP62687.1 - 0.0014 18.6 0.2 0.0029 17.5 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EJP62687.1 - 0.0018 17.6 1.3 0.02 14.2 0.2 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EJP62687.1 - 0.0033 17.4 5.1 0.062 13.3 0.2 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EJP62687.1 - 0.016 15.3 0.1 11 6.1 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EJP62687.1 - 0.018 14.2 0.9 0.038 13.1 0.6 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EJP62687.1 - 0.027 13.8 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP62687.1 - 0.13 10.9 3.2 0.076 11.7 0.3 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EJP62687.1 - 0.15 11.3 1.8 0.14 11.4 0.2 1.7 2 0 0 2 2 2 0 Thi4 family Amino_oxidase PF01593.24 EJP62687.1 - 0.22 10.8 0.1 0.43 9.8 0.1 1.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase PTR2 PF00854.21 EJP62689.1 - 1.2e-40 139.6 0.2 1.6e-40 139.2 0.2 1.1 1 0 0 1 1 1 1 POT family DUF3638 PF12340.8 EJP62691.1 - 1.1e-73 247.3 0.0 3.4e-73 245.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EJP62691.1 - 8.1e-14 50.7 0.9 1.8e-13 49.6 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) HAUS-augmin3 PF14932.6 EJP62693.1 - 4.8e-07 29.6 1.2 4.8e-07 29.6 1.2 2.7 2 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 DDE_Tnp_IS1595 PF12762.7 EJP62693.1 - 0.062 13.3 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 ISXO2-like transposase domain DUF1759 PF03564.15 EJP62693.1 - 0.17 11.9 1.2 0.29 11.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF4795 PF16043.5 EJP62693.1 - 1 8.9 5.8 1.8 8.1 4.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) LrgB PF04172.16 EJP62694.1 - 8.7e-19 67.9 26.3 3.3e-14 52.9 3.4 3.6 4 0 0 4 4 4 3 LrgB-like family 60KD_IMP PF02096.20 EJP62694.1 - 1.2 9.1 10.4 7.2 6.5 3.9 2.6 2 0 0 2 2 2 0 60Kd inner membrane protein Rotamase PF00639.21 EJP62695.1 - 2.9e-21 76.2 0.0 3.9e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EJP62695.1 - 1.4e-14 54.6 0.0 2.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EJP62695.1 - 4.7e-08 33.0 0.7 9.2e-08 32.0 0.2 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EJP62695.1 - 0.0064 17.3 0.0 0.0077 17.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 EJP62695.1 - 0.13 12.0 0.2 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 WW domain RNA_POL_M_15KD PF02150.16 EJP62696.1 - 1.6e-12 47.0 3.0 1.6e-12 47.0 3.0 2.4 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.6 EJP62696.1 - 0.14 11.9 5.7 12 5.7 0.7 3.4 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EJP62696.1 - 5.5 7.0 8.5 1.4 8.9 0.8 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L14 PF00238.19 EJP62697.1 - 4.8e-44 149.3 2.5 5.7e-44 149.1 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.16 EJP62697.1 - 0.06 13.0 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 Flagellar L-ring protein SET PF00856.28 EJP62698.1 - 1.9e-10 41.4 0.2 1.2e-09 38.8 0.2 2.2 1 1 0 1 1 1 1 SET domain Tmemb_55A PF09788.9 EJP62698.1 - 0.00026 20.2 0.1 0.00058 19.0 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 55A FAM76 PF16046.5 EJP62698.1 - 0.035 13.5 0.6 0.077 12.3 0.6 1.5 1 0 0 1 1 1 0 FAM76 protein Gly_transf_sug PF04488.15 EJP62699.1 - 4.8e-09 36.7 0.0 1.3e-08 35.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EJP62699.1 - 0.0066 15.8 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EJP62699.1 - 0.037 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Peptidase_M28 PF04389.17 EJP62701.1 - 1.5e-39 135.8 0.2 2.7e-39 134.9 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EJP62701.1 - 2.9e-11 43.2 0.3 6.8e-11 42.0 0.3 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EJP62701.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 GP57 PF17594.2 EJP62702.1 - 0.043 13.6 1.0 0.36 10.6 0.1 2.1 1 1 1 2 2 2 0 Phage Tail fiber assembly helper gene product 57 HrpB1_HrpK PF09613.10 EJP62703.1 - 0.24 11.0 3.5 0.85 9.3 0.6 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) GIDA_assoc PF13932.6 EJP62703.1 - 0.25 11.5 3.7 0.46 10.7 3.7 1.3 1 0 0 1 1 1 0 GidA associated domain DUF3425 PF11905.8 EJP62705.1 - 4.9e-15 55.6 0.0 9.1e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Bac_thur_toxin PF01338.18 EJP62706.1 - 1.7e-10 40.7 0.8 2.2e-10 40.4 0.8 1.1 1 0 0 1 1 1 1 Bacillus thuringiensis toxin Trypsin_2 PF13365.6 EJP62707.1 - 8.1e-09 36.5 0.0 1.7e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EJP62707.1 - 3.6e-07 30.2 0.1 6.1e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Trypsin Lipase_3 PF01764.25 EJP62708.1 - 1.2e-31 109.5 0.0 2.5e-31 108.4 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EJP62708.1 - 0.002 18.7 0.0 0.0025 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 EJP62708.1 - 0.003 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Esterase PF00756.20 EJP62708.1 - 0.0056 16.4 0.1 0.029 14.0 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.8 EJP62708.1 - 0.021 14.1 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EJP62708.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 EJP62708.1 - 0.048 13.5 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EJP62708.1 - 0.088 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Smg4_UPF3 PF03467.15 EJP62708.1 - 1 9.4 9.1 1.6 8.7 9.1 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family PBP_sp32 PF07222.12 EJP62708.1 - 4.6 6.6 9.0 7.2 6.0 9.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Condensation PF00668.20 EJP62709.1 - 2.5e-113 379.2 0.8 7e-72 242.5 0.1 3.2 3 0 0 3 3 3 2 Condensation domain AMP-binding PF00501.28 EJP62709.1 - 1.5e-69 234.6 0.0 2.3e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EJP62709.1 - 2.3e-25 88.7 0.1 1.9e-11 44.1 0.0 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP62709.1 - 2.9e-13 50.6 0.1 1e-12 48.9 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.22 EJP62710.1 - 1.2e-46 159.4 0.0 6.3e-42 143.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Aminotran_1_2 PF00155.21 EJP62711.1 - 6e-40 137.5 0.0 7.3e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EJP62711.1 - 8e-08 31.6 0.0 1.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EJP62711.1 - 2.9e-06 26.8 0.0 4.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EJP62711.1 - 6.4e-05 21.7 0.0 9.6e-05 21.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 EJP62711.1 - 8.8e-05 21.5 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 EJP62711.1 - 0.004 16.5 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase FA_hydroxylase PF04116.13 EJP62712.1 - 2.1e-19 70.2 8.5 2.1e-19 70.2 8.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sulfotransfer_4 PF17784.1 EJP62713.1 - 1.6e-41 142.5 1.0 9.2e-36 123.7 0.1 2.1 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EJP62713.1 - 0.02 15.3 0.3 0.14 12.5 0.1 2.0 1 1 1 2 2 2 0 Sulfotransferase family Sulfatase PF00884.23 EJP62714.1 - 5.6e-21 75.2 0.6 1.2e-20 74.1 0.6 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EJP62714.1 - 0.00015 21.5 0.0 0.00039 20.1 0.0 1.7 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EJP62714.1 - 0.076 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Cytochrom_B558a PF05038.13 EJP62714.1 - 0.11 12.1 0.9 0.22 11.1 0.9 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit AA_permease PF00324.21 EJP62716.1 - 2.5e-126 422.1 36.2 2.9e-126 421.9 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP62716.1 - 5.7e-36 124.3 42.8 6.7e-36 124.0 42.8 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 EJP62716.1 - 0.033 14.9 0.8 0.033 14.9 0.8 4.6 5 1 1 6 6 6 0 PrgI family protein Lyase_1 PF00206.20 EJP62717.1 - 1.9e-22 80.1 0.1 2.7e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EJP62717.1 - 7.4e-14 52.1 0.0 2.2e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Cupin_2 PF07883.11 EJP62718.1 - 3.7e-07 29.8 1.1 0.0087 15.8 0.4 2.6 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EJP62718.1 - 3.4e-05 23.8 2.4 0.11 12.5 0.3 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.22 EJP62718.1 - 0.00023 20.8 0.1 0.051 13.2 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.12 EJP62718.1 - 0.014 15.1 0.0 3.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF861) Abhydrolase_6 PF12697.7 EJP62719.1 - 3.8e-06 27.7 0.0 4.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EJP62719.1 - 4.1e-06 26.7 0.0 7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 EJP62719.1 - 1.9e-05 24.3 0.0 9.5e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 EJP62719.1 - 0.0015 18.2 0.1 0.0045 16.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 EJP62719.1 - 0.016 14.5 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 EJP62719.1 - 0.022 14.6 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EJP62719.1 - 0.13 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 K_oxygenase PF13434.6 EJP62720.1 - 1.4e-18 67.1 0.1 3e-12 46.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EJP62720.1 - 2.8e-10 39.9 0.1 6.4e-06 25.6 0.1 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP62720.1 - 1.6e-09 37.5 0.5 8.1e-05 22.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP62720.1 - 0.00031 19.6 0.0 0.6 8.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 EJP62720.1 - 0.0048 17.4 0.3 4.8 7.8 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EJP62720.1 - 0.0063 15.6 0.5 0.021 13.9 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EJP62720.1 - 0.0098 16.1 0.1 0.078 13.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP62720.1 - 0.017 14.7 9.5 1.3 8.5 9.1 3.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EJP62720.1 - 0.021 14.1 0.1 2.7 7.2 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EJP62720.1 - 0.05 12.7 0.6 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EJP62720.1 - 0.076 12.2 0.3 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EJP62720.1 - 0.12 12.4 4.7 6 6.8 0.4 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EJP62721.1 - 1.6e-92 310.5 0.2 2.5e-92 309.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EJP62721.1 - 1.6e-50 171.3 0.0 3e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EJP62721.1 - 8e-05 21.9 0.1 0.00016 20.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EJP62721.1 - 0.00019 20.2 0.2 0.0003 19.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EJP62721.1 - 0.00051 19.4 0.1 0.00089 18.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP62721.1 - 0.00061 19.1 0.2 0.0013 18.0 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EJP62721.1 - 0.0013 17.9 0.1 0.0024 17.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EJP62721.1 - 0.011 16.0 0.1 0.042 14.1 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EJP62721.1 - 0.015 14.4 0.4 0.034 13.2 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 EJP62721.1 - 0.032 13.5 0.1 0.059 12.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EJP62721.1 - 0.15 12.7 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HisG PF01634.18 EJP62722.1 - 1.2e-53 181.3 0.0 1.7e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EJP62722.1 - 6e-28 96.8 0.2 1.5e-27 95.5 0.2 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain A_deaminase PF00962.22 EJP62723.1 - 7.6e-121 403.4 0.1 1.2e-120 402.8 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 EJP62723.1 - 0.012 14.9 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 UAA transporter family SH3_1 PF00018.28 EJP62724.1 - 4e-37 125.6 7.5 3.3e-13 49.0 0.4 4.2 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 EJP62724.1 - 8.6e-35 118.4 0.0 1.6e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 EJP62724.1 - 1e-31 108.5 5.7 1.9e-12 46.9 0.2 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 EJP62724.1 - 1.2e-20 72.9 0.1 3.3e-08 33.1 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 EJP62724.1 - 9.3e-07 28.7 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 EJP62724.1 - 0.00065 19.9 2.0 0.023 15.0 0.2 3.2 3 0 0 3 3 3 1 Bacterial SH3 domain SH3_10 PF17902.1 EJP62724.1 - 0.0017 18.4 0.1 0.17 12.0 0.0 3.0 3 0 0 3 3 3 1 SH3 domain DUF1720 PF08226.11 EJP62724.1 - 0.0032 17.9 25.9 0.0032 17.9 25.9 5.7 1 1 3 4 4 4 2 Domain of unknown function (DUF1720) TRAM_LAG1_CLN8 PF03798.16 EJP62725.1 - 5.4e-47 160.1 16.9 5.4e-47 160.1 16.9 1.4 2 0 0 2 2 2 1 TLC domain DUF2178 PF09946.9 EJP62725.1 - 0.1 12.8 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Dor1 PF04124.12 EJP62726.1 - 4e-37 127.7 0.1 3.5e-28 98.3 0.6 2.1 2 0 0 2 2 2 2 Dor1-like family Mito_carr PF00153.27 EJP62727.1 - 3.2e-32 110.3 0.4 3.8e-17 62.0 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein Prefoldin_2 PF01920.20 EJP62729.1 - 1.4e-16 60.3 7.0 1.8e-16 60.0 7.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3958 PF13125.6 EJP62729.1 - 0.0085 16.3 3.1 0.0085 16.3 3.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3958) TMF_TATA_bd PF12325.8 EJP62729.1 - 0.0098 16.1 1.1 0.0098 16.1 1.1 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF4378 PF14309.6 EJP62729.1 - 0.016 15.6 0.2 0.021 15.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Csm1_B PF18211.1 EJP62729.1 - 0.02 14.7 0.0 0.063 13.1 0.0 1.9 1 1 0 1 1 1 0 Csm1 subunit domain B DUF1640 PF07798.11 EJP62729.1 - 0.029 14.4 5.4 0.047 13.7 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) FlxA PF14282.6 EJP62729.1 - 0.046 13.7 13.3 0.88 9.6 0.6 2.1 2 0 0 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 EJP62729.1 - 0.054 13.7 0.6 0.054 13.7 0.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 EJP62729.1 - 0.12 12.8 10.4 0.087 13.2 4.5 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region T6PP_N PF18572.1 EJP62729.1 - 0.18 11.7 3.5 0.33 10.8 3.5 1.5 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Spc24 PF08286.11 EJP62729.1 - 0.23 11.7 7.0 0.31 11.3 1.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prominin PF05478.11 EJP62729.1 - 0.25 9.2 4.1 0.28 9.1 4.1 1.0 1 0 0 1 1 1 0 Prominin XkdW PF09636.10 EJP62729.1 - 0.32 11.1 2.8 5.4 7.2 0.2 2.2 2 0 0 2 2 2 0 XkdW protein CdvA PF18822.1 EJP62729.1 - 0.34 10.8 8.9 1.8 8.4 1.3 3.0 2 2 2 4 4 4 0 CdvA-like coiled-coil domain Rab_bind PF16704.5 EJP62729.1 - 0.35 10.9 7.7 1.8 8.7 0.4 3.0 2 1 1 3 3 3 0 Rab binding domain Tup_N PF08581.10 EJP62729.1 - 0.44 10.9 8.0 0.11 12.8 1.6 2.3 2 1 0 2 2 2 0 Tup N-terminal DNA_topoisoIV PF00521.20 EJP62729.1 - 0.57 9.0 5.3 0.72 8.7 5.3 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A EMP24_GP25L PF01105.24 EJP62729.1 - 0.9 9.5 8.1 1.4 8.8 6.6 1.9 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD CLZ PF16526.5 EJP62729.1 - 1.1 9.7 8.4 0.11 12.9 2.6 2.1 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Macoilin PF09726.9 EJP62729.1 - 1.1 7.7 8.1 1.4 7.4 8.1 1.1 1 0 0 1 1 1 0 Macoilin family MctB PF11382.8 EJP62729.1 - 1.2 8.8 5.2 0.28 10.8 0.6 1.9 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB DUF4200 PF13863.6 EJP62729.1 - 1.3 9.4 11.3 1.6 9.1 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) YabA PF06156.13 EJP62729.1 - 1.6 9.4 7.5 0.9 10.2 1.5 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Swi5 PF07061.11 EJP62729.1 - 1.7 8.8 10.1 0.58 10.3 1.8 2.2 2 0 0 2 2 2 0 Swi5 bZIP_1 PF00170.21 EJP62729.1 - 2.1 8.5 8.8 0.47 10.6 4.0 2.1 2 1 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 EJP62729.1 - 2.8 7.8 11.0 0.16 11.8 1.2 2.5 2 1 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 EJP62729.1 - 3.3 8.2 12.5 0.24 11.9 3.8 2.2 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 EJP62729.1 - 4.3 7.5 12.4 0.11 12.6 2.9 2.7 3 0 0 3 3 3 0 Basic region leucine zipper GTP_EFTU PF00009.27 EJP62730.1 - 1.2e-49 168.5 0.0 2.2e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EJP62730.1 - 2.8e-43 146.4 3.4 5.2e-43 145.6 3.4 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EJP62730.1 - 3.8e-20 71.7 0.0 7.6e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 EJP62730.1 - 3.4e-05 23.9 0.1 0.00016 21.7 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EJP62730.1 - 3.4e-05 24.1 1.4 5.9e-05 23.4 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EJP62730.1 - 9.8e-05 22.4 0.0 0.00025 21.1 0.0 1.7 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 EJP62730.1 - 0.0019 17.8 0.0 0.0075 15.9 0.0 1.9 2 0 0 2 2 2 1 Ras family RF3_C PF16658.5 EJP62730.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EJP62730.1 - 0.018 14.4 0.1 0.067 12.6 0.0 2.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EJP62730.1 - 0.062 13.5 0.1 0.6 10.3 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MIT PF04212.18 EJP62731.1 - 1.1e-14 54.2 3.3 2e-14 53.4 3.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Ribosomal_L30 PF00327.20 EJP62732.1 - 5.6e-16 58.2 0.0 7.2e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.13 EJP62733.1 - 3.2e-56 189.8 0.1 4.2e-56 189.4 0.1 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EJP62733.1 - 5e-06 26.3 0.5 8.8e-06 25.5 0.5 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Glyco_hyd_65N_2 PF14498.6 EJP62734.1 - 2e-57 194.8 0.3 3.1e-57 194.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain NAD_binding_4 PF07993.12 EJP62735.1 - 1.9e-71 240.2 0.0 3.2e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EJP62735.1 - 3.8e-69 233.3 0.0 7.2e-69 232.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EJP62735.1 - 4.1e-10 39.9 0.0 9.6e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EJP62735.1 - 1.8e-09 37.4 0.0 3.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EJP62735.1 - 1.1e-07 31.1 0.0 2.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EJP62735.1 - 0.00019 22.3 0.0 0.00076 20.4 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 EJP62735.1 - 0.13 11.3 0.0 0.32 10.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Cnl2_NKP2 PF09447.10 EJP62736.1 - 2.8e-22 78.6 1.0 1.1e-21 76.7 0.0 2.2 2 0 0 2 2 2 1 Cnl2/NKP2 family protein Prefoldin_2 PF01920.20 EJP62736.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit EMP24_GP25L PF01105.24 EJP62736.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD BRD4_CDT PF17105.5 EJP62736.1 - 2.6 7.7 8.0 2.2 7.9 0.3 2.6 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 RTP1_C1 PF10363.9 EJP62739.1 - 2.1e-23 82.6 1.6 2.1e-22 79.4 0.2 2.9 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EJP62739.1 - 8.3e-13 47.7 0.9 8.3e-13 47.7 0.9 2.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 DUF3384 PF11864.8 EJP62739.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) DNA_pol_phi PF04931.13 EJP62739.1 - 0.11 10.6 5.1 0.22 9.6 5.1 1.5 1 0 0 1 1 1 0 DNA polymerase phi DUF4778 PF16008.5 EJP62739.1 - 0.13 12.3 1.2 0.26 11.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) T2SSF PF00482.23 EJP62739.1 - 0.15 12.0 1.6 1.5 8.8 0.1 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F RIX1 PF08167.12 EJP62739.1 - 0.21 11.3 1.3 3.1 7.5 0.0 3.0 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis FAM176 PF14851.6 EJP62739.1 - 1.2 8.7 4.8 0.3 10.8 1.1 1.9 2 0 0 2 2 2 0 FAM176 family OB_NTP_bind PF07717.16 EJP62741.1 - 6.8e-24 84.0 0.0 9.7e-23 80.3 0.0 2.7 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EJP62741.1 - 4.7e-18 65.5 0.0 1.6e-17 63.8 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EJP62741.1 - 7.2e-12 45.6 0.0 3.3e-11 43.5 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP62741.1 - 3.1e-08 33.6 0.1 6.6e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJP62741.1 - 1e-05 25.8 0.0 2.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EJP62741.1 - 9.8e-05 22.1 0.2 0.00057 19.6 0.2 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 EJP62741.1 - 0.0023 17.0 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EJP62741.1 - 0.0026 18.2 0.1 0.052 14.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EJP62741.1 - 0.0084 16.5 0.1 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP62741.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EJP62741.1 - 0.014 15.4 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EJP62741.1 - 0.036 14.0 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain NB-ARC PF00931.22 EJP62741.1 - 0.16 11.1 0.0 0.7 9.0 0.0 2.0 2 1 1 3 3 3 0 NB-ARC domain PRMT5 PF05185.16 EJP62742.1 - 2.6e-68 229.3 0.0 4.4e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 EJP62742.1 - 2.5e-63 213.7 0.0 3.6e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 EJP62742.1 - 3.1e-57 193.3 0.0 4.9e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 EJP62742.1 - 0.00035 20.4 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Aminotran_5 PF00266.19 EJP62743.1 - 3.9e-28 98.5 0.0 5.1e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EJP62743.1 - 0.024 13.2 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CRM1_C PF08767.11 EJP62744.1 - 1.3e-131 438.6 2.2 1.3e-131 438.6 2.2 2.7 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EJP62744.1 - 1.2e-40 139.0 13.0 9.8e-40 136.0 7.1 4.2 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EJP62744.1 - 1.1e-33 114.7 4.2 3.8e-33 112.9 4.2 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EJP62744.1 - 5.2e-28 96.9 6.0 2.1e-27 95.0 0.8 4.0 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EJP62744.1 - 7.7e-20 70.1 2.6 2.1e-19 68.7 2.6 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EJP62744.1 - 9.8e-14 51.0 0.1 3.5e-13 49.3 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Hemocyanin_M PF00372.19 EJP62744.1 - 0.012 14.8 0.3 0.12 11.6 0.0 2.5 2 1 0 2 2 2 0 Hemocyanin, copper containing domain BID PF06393.11 EJP62744.1 - 0.029 13.9 0.1 0.083 12.4 0.1 1.8 1 0 0 1 1 1 0 BH3 interacting domain (BID) Vac14_Fab1_bd PF12755.7 EJP62744.1 - 0.21 12.2 3.3 7.3 7.3 0.0 4.6 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EJP62744.1 - 0.23 11.4 9.6 0.36 10.7 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Zn_clus PF00172.18 EJP62745.1 - 5e-08 32.9 8.9 9.9e-08 32.0 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TERB2 PF15101.6 EJP62745.1 - 0.076 13.1 0.3 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 EJP62745.1 - 1.7 8.2 11.3 3.6 7.1 11.3 1.4 1 0 0 1 1 1 0 Spt20 family RTA1 PF04479.13 EJP62746.1 - 1.7e-67 227.1 13.3 2.5e-67 226.5 13.3 1.2 1 0 0 1 1 1 1 RTA1 like protein DEAD PF00270.29 EJP62747.1 - 4e-35 121.1 0.0 9e-35 120.0 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP62747.1 - 1e-21 77.4 0.0 2.1e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EJP62747.1 - 2.5e-19 69.3 0.1 4.7e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EJP62747.1 - 0.013 15.6 0.2 0.04 13.9 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Mcm10 PF09332.11 EJP62747.1 - 0.034 13.6 11.0 0.05 13.0 11.0 1.2 1 0 0 1 1 1 0 Mcm10 replication factor PPL5 PF18168.1 EJP62747.1 - 1.5 8.0 11.2 2.4 7.4 11.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 eIF3_subunit PF08597.10 EJP62747.1 - 3.3 7.6 24.6 5.8 6.8 24.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit KxDL PF10241.9 EJP62749.1 - 6e-31 106.6 0.7 8.1e-31 106.2 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.11 EJP62749.1 - 0.041 13.6 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism UPF0242 PF06785.11 EJP62749.1 - 0.11 12.6 1.4 0.14 12.2 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2985 PF11204.8 EJP62751.1 - 1.2e-20 73.4 2.2 2.3e-20 72.5 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sulfate_transp PF00916.20 EJP62752.1 - 1.4e-108 363.1 22.0 1.8e-108 362.7 22.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EJP62752.1 - 7.7e-09 35.2 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EJP62752.1 - 0.00064 20.1 19.5 0.0054 17.1 3.9 2.7 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EJP62752.1 - 0.07 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 STAS domain SNN_transmemb PF09049.10 EJP62752.1 - 0.087 12.8 3.1 0.42 10.6 3.1 2.3 1 0 0 1 1 1 0 Stannin transmembrane GST_N_3 PF13417.6 EJP62753.1 - 2.1e-11 44.1 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP62753.1 - 2.1e-10 40.8 0.0 3.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EJP62753.1 - 1.7e-08 34.7 0.0 2.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EJP62753.1 - 2.1e-07 31.0 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EJP62753.1 - 9.1e-07 29.0 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EJP62753.1 - 0.00013 21.9 0.2 0.00031 20.7 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain APH PF01636.23 EJP62753.1 - 0.07 13.0 0.2 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Acetyltransf_1 PF00583.25 EJP62754.1 - 2.5e-20 72.8 0.0 2.5e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP62754.1 - 2.3e-13 50.3 0.0 6.5e-09 36.1 0.0 2.8 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP62754.1 - 5.2e-10 39.3 0.0 4.2e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EJP62754.1 - 5.9e-09 36.7 0.0 0.00023 21.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EJP62754.1 - 1.2e-06 28.5 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EJP62754.1 - 1.4e-06 28.4 0.0 0.014 15.5 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP62754.1 - 1.5e-06 28.1 0.0 0.001 19.0 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.6 EJP62754.1 - 5.8e-05 22.8 0.0 0.41 10.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJP62754.1 - 0.0059 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 EJP62754.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Nudix hydrolase domain Acetyltransf_2 PF00797.17 EJP62755.1 - 2.2e-44 152.0 0.1 8.6e-44 150.1 0.1 1.9 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 EJP62755.1 - 0.0073 16.8 0.1 0.03 14.8 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily HRI1 PF16815.5 EJP62756.1 - 1.5e-66 224.4 0.1 1.7e-66 224.2 0.1 1.0 1 0 0 1 1 1 1 Protein HRI1 Nucleos_tra2_C PF07662.13 EJP62757.1 - 1.7e-69 233.9 2.6 1.7e-69 233.9 2.6 2.5 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EJP62757.1 - 1.5e-23 83.1 1.5 1.5e-23 83.1 1.5 3.1 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 EJP62757.1 - 5.6 7.3 15.8 0.52 10.6 7.7 3.1 2 1 0 2 2 2 0 Nucleoside recognition VPS13_mid_rpt PF16910.5 EJP62758.1 - 1.3e-92 309.5 13.9 3.9e-90 301.4 0.2 5.8 6 1 0 6 6 6 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 EJP62758.1 - 7.4e-92 307.6 0.0 1.1e-89 300.5 0.0 3.4 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 EJP62758.1 - 2.6e-86 289.3 0.4 4.4e-85 285.2 0.2 2.9 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EJP62758.1 - 5.9e-77 257.5 5.5 2.8e-71 239.0 0.6 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EJP62758.1 - 3.2e-40 136.9 0.2 2.8e-39 133.8 0.0 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EJP62758.1 - 3.1e-07 30.6 0.0 9.9e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain SLBP_RNA_bind PF15247.6 EJP62758.1 - 0.65 10.2 3.9 1.7 8.8 2.6 2.3 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain DUF896 PF05979.12 EJP62758.1 - 5.7 6.9 5.7 31 4.5 0.5 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Fungal_trans_2 PF11951.8 EJP62759.1 - 6e-10 38.5 0.0 1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP62759.1 - 2.2e-07 30.9 7.2 3.7e-07 30.1 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLASP_N PF12348.8 EJP62760.1 - 3.3e-08 33.4 0.0 5.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 EJP62760.1 - 0.0028 17.7 0.0 0.013 15.5 0.1 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HALZ PF02183.18 EJP62760.1 - 0.025 14.8 8.0 0.067 13.4 1.7 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper TAN PF11640.8 EJP62760.1 - 0.042 14.0 0.1 0.17 12.0 0.1 2.1 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair CCDC144C PF14915.6 EJP62760.1 - 0.57 9.2 8.3 1 8.4 8.3 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Fez1 PF06818.15 EJP62760.1 - 0.8 10.1 5.3 2.3 8.6 5.3 1.7 1 0 0 1 1 1 0 Fez1 SHE3 PF17078.5 EJP62760.1 - 0.99 9.1 7.6 1.9 8.2 7.6 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Hc1 PF07432.13 EJP62760.1 - 1.2 9.6 8.9 3.9 7.9 8.9 1.9 1 0 0 1 1 1 0 Histone H1-like protein Hc1 PRKG1_interact PF15898.5 EJP62760.1 - 1.3 10.0 12.4 0.65 10.9 9.2 2.2 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 EJP62760.1 - 1.4 7.7 5.3 1.1 8.1 3.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 EJP62760.1 - 1.5 8.1 7.0 0.42 9.9 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 EJP62760.1 - 1.7 9.0 5.1 5.4 7.3 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) YabA PF06156.13 EJP62760.1 - 2 9.1 3.7 12 6.6 3.6 2.3 1 1 0 1 1 1 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 EJP62760.1 - 2.3 8.3 3.9 16 5.5 1.7 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 EJP62760.1 - 2.7 8.5 8.6 4.1 8.0 6.7 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region KLRAQ PF10205.9 EJP62760.1 - 3.3 8.0 6.2 28 5.0 1.5 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Jnk-SapK_ap_N PF09744.9 EJP62760.1 - 4.8 7.4 13.4 0.79 9.9 8.9 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 GCFC PF07842.12 EJP62761.1 - 4.7e-62 210.1 1.1 8.4e-62 209.3 1.1 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EJP62761.1 - 4.4e-14 52.1 3.4 1.1e-13 50.8 3.4 1.8 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 EJP62761.1 - 5.8e-11 42.7 7.8 5.8e-11 42.7 7.8 3.7 3 1 0 3 3 3 2 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 EJP62761.1 - 1.1e-07 31.8 1.6 1.1e-07 31.8 1.6 2.9 3 0 0 3 3 3 1 G-patch domain SAPS PF04499.15 EJP62762.1 - 2.9e-187 623.4 0.0 6e-187 622.3 0.0 1.6 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein OPT PF03169.15 EJP62763.1 - 2.1e-173 578.3 46.3 2.4e-173 578.1 46.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Abhydrolase_2 PF02230.16 EJP62764.1 - 1.7e-62 211.1 0.0 1.9e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EJP62764.1 - 9.2e-07 28.4 1.0 0.0017 17.6 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 EJP62764.1 - 2e-05 24.3 0.0 3.8e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EJP62764.1 - 2.3e-05 24.0 2.0 0.0054 16.2 0.0 3.0 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EJP62764.1 - 0.00016 22.3 1.3 0.00022 21.9 1.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EJP62764.1 - 0.00073 19.5 0.2 1.3 8.8 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 EJP62764.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EJP62764.1 - 0.32 10.6 3.0 16 5.0 0.1 2.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Rtt106 PF08512.12 EJP62765.1 - 6e-30 103.5 0.0 1.5e-29 102.3 0.0 1.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EJP62765.1 - 0.07 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain NOA36 PF06524.12 EJP62765.1 - 0.32 10.3 24.3 0.46 9.7 24.3 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EJP62765.1 - 6.6 6.4 23.0 14 5.3 23.0 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.10 EJP62766.1 - 3e-52 177.6 27.6 3.5e-52 177.4 27.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Dynactin_p62 PF05502.13 EJP62766.1 - 0.0044 15.9 7.9 0.005 15.7 7.9 1.2 1 0 0 1 1 1 1 Dynactin p62 family SLC12 PF03522.15 EJP62766.1 - 0.75 8.8 13.3 0.88 8.5 13.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIIAH PF12685.7 EJP62766.1 - 0.76 9.6 15.0 1.3 8.8 15.0 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF913 PF06025.12 EJP62766.1 - 0.96 8.4 7.7 0.98 8.3 7.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 EJP62766.1 - 1.1 7.3 11.5 1.3 7.1 11.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rrn6 PF10214.9 EJP62766.1 - 2.1 6.7 11.9 2.4 6.6 11.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF5427 PF10310.9 EJP62766.1 - 2.6 6.9 17.9 3.3 6.5 17.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Serinc PF03348.15 EJP62766.1 - 2.6 6.9 3.7 3 6.7 3.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_11 PF13086.6 EJP62766.1 - 3.6 7.3 11.9 4.7 6.9 11.9 1.3 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EJP62766.1 - 4.3 6.6 11.0 4.9 6.4 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLN3 PF02487.17 EJP62766.1 - 4.3 6.3 4.4 5.1 6.0 4.4 1.3 1 0 0 1 1 1 0 CLN3 protein SID-1_RNA_chan PF13965.6 EJP62766.1 - 4.7 5.5 6.2 5.3 5.3 6.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 EJP62766.1 - 5.7 6.7 24.0 8 6.2 24.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EJP62766.1 - 7.5 5.2 15.3 8.5 5.0 15.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.8 EJP62766.1 - 8 5.1 19.1 12 4.5 19.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BT1 PF03092.16 EJP62766.1 - 8 4.6 7.3 8.7 4.4 7.3 1.1 1 0 0 1 1 1 0 BT1 family CDC45 PF02724.14 EJP62766.1 - 8 4.6 28.2 9.8 4.3 28.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DSPc PF00782.20 EJP62767.1 - 3.3e-15 56.1 0.0 8.6e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EJP62767.1 - 0.0095 16.2 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain DUF1233 PF06806.12 EJP62767.1 - 0.036 13.7 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative excisionase (DUF1233) GD_N PF16030.5 EJP62767.1 - 0.12 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine protease gd N-terminus zinc_ribbon_4 PF13717.6 EJP62767.1 - 0.38 10.7 0.1 0.38 10.7 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain GATase_5 PF13507.6 EJP62768.1 - 1.9e-96 322.2 0.0 2.9e-96 321.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EJP62768.1 - 4.7e-34 117.8 0.9 9.3e-24 84.3 0.1 2.7 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EJP62768.1 - 1.5e-25 89.4 0.0 2.7e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EJP62768.1 - 5e-22 78.2 0.0 1.1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF3378 PF11858.8 EJP62768.1 - 0.17 12.1 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) zf-C2H2 PF00096.26 EJP62769.1 - 0.0016 18.8 20.8 0.003 17.9 0.7 4.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-CHCC PF10276.9 EJP62769.1 - 0.013 15.5 2.7 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-MYST PF17772.1 EJP62769.1 - 0.13 11.8 3.1 0.19 11.3 0.3 2.3 2 0 0 2 2 2 0 MYST family zinc finger domain zf-BED PF02892.15 EJP62769.1 - 0.25 11.4 11.2 0.86 9.7 0.2 4.0 4 0 0 4 4 4 0 BED zinc finger zf-C2H2_4 PF13894.6 EJP62769.1 - 0.74 10.8 20.9 0.14 13.1 1.1 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 EJP62769.1 - 1.1 9.8 6.0 2.5 8.7 1.3 2.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain PyrI_C PF02748.15 EJP62769.1 - 4.4 7.3 6.5 4.2 7.3 1.0 2.6 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain PH_10 PF15411.6 EJP62771.1 - 2.6e-39 134.3 0.3 5.4e-39 133.3 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EJP62771.1 - 1.3e-29 102.2 0.0 2.9e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 EJP62771.1 - 5.7e-27 95.1 0.0 9.5e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EJP62771.1 - 5.9e-09 35.8 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 EJP62772.1 - 5.4e-24 84.0 6.1 0.0016 19.2 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 EJP62772.1 - 1.5e-14 53.6 3.3 3.2e-14 52.5 3.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP62772.1 - 8.3e-07 28.7 1.1 1.5e-06 27.9 0.6 1.8 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EJP62772.1 - 3.7e-05 23.9 0.0 2.7 8.3 0.0 4.3 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP62772.1 - 0.0049 15.6 0.0 0.21 10.2 0.0 2.4 2 0 0 2 2 2 1 Nucleoporin Nup120/160 MgtE_N PF03448.17 EJP62772.1 - 0.012 16.2 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain SmpA_OmlA PF04355.13 EJP62772.1 - 0.017 14.9 0.1 0.87 9.4 0.0 2.9 2 0 0 2 2 2 0 SmpA / OmlA family F-box_4 PF15966.5 EJP62772.1 - 0.028 14.3 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box PALB2_WD40 PF16756.5 EJP62772.1 - 0.16 10.8 0.0 2.5 7.0 0.0 2.4 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain zf-C4H2 PF10146.9 EJP62772.1 - 0.94 9.7 5.0 0.97 9.7 0.0 2.8 3 0 0 3 3 3 0 Zinc finger-containing protein Snf7 PF03357.21 EJP62773.1 - 1.1e-39 135.8 10.0 1.3e-39 135.5 10.0 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 EJP62773.1 - 0.00022 21.6 4.4 0.024 15.1 1.1 2.8 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein HrpB7 PF09486.10 EJP62773.1 - 0.0031 17.9 4.3 1.2 9.5 1.7 2.4 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB7) Zwint PF15556.6 EJP62773.1 - 0.01 15.4 7.4 0.014 14.9 7.4 1.2 1 0 0 1 1 1 0 ZW10 interactor CENP-F_leu_zip PF10473.9 EJP62773.1 - 0.013 15.5 11.4 0.11 12.5 11.7 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliD_C PF07195.12 EJP62773.1 - 0.038 13.4 3.1 0.31 10.4 0.0 2.5 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF4201 PF13870.6 EJP62773.1 - 0.039 13.7 9.0 0.84 9.3 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HsbA PF12296.8 EJP62773.1 - 0.044 14.2 0.3 0.7 10.3 0.0 2.2 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Peptidase_S46 PF10459.9 EJP62773.1 - 0.049 12.3 4.2 0.059 12.0 4.2 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF4407 PF14362.6 EJP62773.1 - 0.082 12.2 3.1 0.099 12.0 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2205 PF10224.9 EJP62773.1 - 0.092 12.8 4.7 0.15 12.1 1.5 2.8 2 1 1 3 3 3 0 Short coiled-coil protein DUF1664 PF07889.12 EJP62773.1 - 0.16 12.0 6.6 5.8 7.0 2.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 EJP62773.1 - 0.17 11.8 1.2 37 4.2 0.0 2.4 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Med4 PF10018.9 EJP62773.1 - 0.23 11.1 5.5 0.47 10.1 0.1 2.5 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 NYD-SP28_assoc PF14775.6 EJP62773.1 - 0.24 11.5 2.9 12 6.1 0.4 2.7 2 1 1 3 3 2 0 Sperm tail C-terminal domain Mod_r PF07200.13 EJP62773.1 - 0.54 10.4 8.7 0.28 11.3 6.0 1.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Muted PF14942.6 EJP62773.1 - 0.69 10.2 8.4 2.4 8.5 3.0 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF848 PF05852.11 EJP62773.1 - 0.7 10.0 6.7 0.63 10.2 4.3 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) YabA PF06156.13 EJP62773.1 - 1.6 9.4 7.1 9.8 6.9 4.7 2.6 1 1 1 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 EJP62773.1 - 1.6 7.9 12.5 11 5.3 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 EJP62773.1 - 2 9.1 4.8 18 6.1 0.0 3.2 1 1 2 3 3 3 0 SlyX DUF4446 PF14584.6 EJP62773.1 - 7 6.6 6.6 13 5.7 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) FlaC_arch PF05377.11 EJP62773.1 - 9 6.8 9.7 21 5.6 1.9 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) zf_PR_Knuckle PF18445.1 EJP62776.1 - 0.0017 18.2 0.2 0.0042 16.9 0.2 1.7 1 0 0 1 1 1 1 PR zinc knuckle motif Linker_histone PF00538.19 EJP62777.1 - 0.027 14.8 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family Zn_clus PF00172.18 EJP62780.1 - 0.0013 18.9 9.2 0.0025 17.9 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 EJP62780.1 - 0.087 11.9 0.7 0.12 11.4 0.7 1.2 1 0 0 1 1 1 0 Clusterin DUF4281 PF14108.6 EJP62780.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) zf-HC5HC2H_2 PF13832.6 EJP62780.1 - 1.4 9.1 6.9 0.67 10.1 4.1 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain CFEM PF05730.11 EJP62782.1 - 1.3e-24 86.0 15.8 4.2e-14 52.4 2.3 5.9 6 1 0 6 6 6 2 CFEM domain Pectate_lyase_3 PF12708.7 EJP62783.1 - 1.2e-76 257.3 8.5 4.9e-66 222.6 6.0 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EJP62783.1 - 9e-06 25.3 2.1 0.011 15.4 0.5 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.6 EJP62783.1 - 0.00013 22.3 3.9 0.0044 17.4 0.0 4.0 5 0 0 5 5 5 1 Deoxyribonuclease NucA/NucB TPR_12 PF13424.6 EJP62785.1 - 4.8e-30 103.7 23.6 2.9e-06 27.5 0.4 6.7 3 1 3 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 EJP62785.1 - 2.2e-21 75.0 24.4 3.4e-05 23.6 0.3 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 EJP62785.1 - 1.2e-17 62.9 4.2 0.0025 17.6 0.0 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP62785.1 - 2.9e-15 55.1 12.1 0.84 9.9 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP62785.1 - 3.4e-14 53.0 21.3 1e-05 25.1 1.5 4.6 2 1 3 5 5 5 4 MalT-like TPR region TPR_7 PF13176.6 EJP62785.1 - 9.8e-10 37.8 8.6 0.079 13.0 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EJP62785.1 - 2.6e-09 37.1 27.2 0.15 13.0 0.1 10.2 7 3 4 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 EJP62785.1 - 3.2e-05 23.8 13.4 0.24 11.7 0.1 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP62785.1 - 0.00016 22.3 29.6 0.052 14.2 0.1 7.8 7 2 1 8 8 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJP62785.1 - 0.0018 18.5 0.4 66 4.2 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EJP62785.1 - 0.02 14.6 5.1 13 5.5 0.0 5.6 6 0 0 6 6 6 0 TPR repeat TPR_4 PF07721.14 EJP62785.1 - 1.1 10.1 27.9 1.6 9.6 0.0 7.0 8 0 0 8 8 6 0 Tetratricopeptide repeat Enterotoxin_a PF01375.17 EJP62787.1 - 1.7e-28 100.0 0.2 1.2e-14 54.6 0.0 3.2 3 0 0 3 3 3 2 Heat-labile enterotoxin alpha chain CM_1 PF07736.11 EJP62787.1 - 0.23 11.9 0.3 0.5 10.8 0.3 1.5 1 0 0 1 1 1 0 Chorismate mutase type I SGL PF08450.12 EJP62788.1 - 3.2e-17 62.9 0.0 1e-16 61.3 0.0 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 EJP62788.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Proteasome_A_N PF10584.9 EJP62788.1 - 0.13 12.0 0.1 16 5.3 0.1 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature CorA PF01544.18 EJP62789.1 - 1.1e-12 47.9 0.7 1.6e-12 47.4 0.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF615 PF04751.14 EJP62789.1 - 1.3 9.0 6.5 2.1 8.3 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF615) TrkH PF02386.16 EJP62790.1 - 8.1e-88 295.1 1.1 8.1e-88 295.1 1.1 1.4 2 0 0 2 2 2 1 Cation transport protein DUF2755 PF10954.8 EJP62790.1 - 0.074 13.0 0.1 0.5 10.3 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2755) Hydantoinase_B PF02538.14 EJP62791.1 - 3.5e-217 721.9 0.2 5.4e-217 721.3 0.2 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EJP62791.1 - 2.7e-103 345.2 1.2 5.6e-103 344.2 1.2 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EJP62791.1 - 6.2e-63 211.7 2.5 1.2e-61 207.5 0.2 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region ketoacyl-synt PF00109.26 EJP62792.1 - 2e-78 263.5 0.9 1e-76 257.9 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EJP62792.1 - 1.6e-43 149.4 0.1 8.2e-41 140.5 0.0 2.4 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP62792.1 - 6.3e-33 113.3 0.1 1.8e-32 111.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EJP62792.1 - 4.3e-24 84.6 3.9 1.3e-11 44.6 0.9 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site SAT PF16073.5 EJP62792.1 - 1.7e-22 80.3 1.3 1.1e-20 74.4 1.1 2.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 EJP62792.1 - 1.5e-16 61.2 0.1 8.6e-15 55.5 0.0 3.2 3 0 0 3 3 3 1 Thioesterase domain PS-DH PF14765.6 EJP62792.1 - 3.6e-13 49.4 0.0 7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 EJP62792.1 - 5.2e-07 30.5 1.3 0.00011 22.9 0.4 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 EJP62792.1 - 0.00012 22.5 0.0 0.00028 21.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EJP62792.1 - 0.0018 17.7 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EJP62792.1 - 0.013 15.4 0.2 0.048 13.5 0.2 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Lipase_3 PF01764.25 EJP62792.1 - 0.039 13.8 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_1 PF00561.20 EJP62792.1 - 0.066 12.8 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EJP62792.1 - 0.18 11.6 0.1 0.81 9.4 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.16 EJP62793.1 - 2.5e-23 82.6 21.7 2.5e-23 82.6 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EJP62793.1 - 0.0002 20.8 0.5 0.00052 19.4 0.5 1.7 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PTR2 PF00854.21 EJP62793.1 - 0.026 13.4 0.0 4.2 6.1 0.1 2.3 2 0 0 2 2 2 0 POT family BT1 PF03092.16 EJP62793.1 - 3.4 5.8 6.7 10 4.2 0.2 2.8 3 0 0 3 3 3 0 BT1 family Fungal_trans PF04082.18 EJP62794.1 - 9.3e-09 34.7 0.1 2.3e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP62794.1 - 0.00067 19.7 14.9 0.0016 18.5 14.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 EJP62795.1 - 8.3e-27 94.3 0.0 1.4e-26 93.6 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJP62795.1 - 1.3e-11 44.7 3.8 3.7e-06 26.8 0.4 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP62795.1 - 5.6e-09 35.6 2.7 1.2e-07 31.2 0.2 2.3 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EJP62795.1 - 8.3e-09 35.1 0.8 0.0013 18.1 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP62795.1 - 9.8e-08 32.5 0.0 0.0074 16.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP62795.1 - 3e-06 26.2 0.1 0.00097 17.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 EJP62795.1 - 1.2e-05 25.4 0.1 3.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EJP62795.1 - 2.7e-05 23.4 0.2 0.034 13.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 EJP62795.1 - 0.00087 18.5 0.1 0.0018 17.4 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EJP62795.1 - 0.0016 17.8 0.9 0.0027 17.1 0.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EJP62795.1 - 0.012 14.9 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EJP62795.1 - 0.018 13.9 0.0 0.042 12.7 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EJP62795.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 EJP62795.1 - 0.11 11.7 0.3 0.54 9.5 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Cu-oxidase_3 PF07732.15 EJP62796.1 - 4.9e-43 145.9 2.4 4.9e-43 145.9 2.4 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP62796.1 - 3.1e-39 133.8 8.9 9.3e-37 125.8 0.5 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EJP62796.1 - 5.4e-36 124.1 0.0 2.1e-35 122.2 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase GST_N_3 PF13417.6 EJP62797.1 - 2.5e-14 53.4 0.0 4.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EJP62797.1 - 2.5e-13 50.1 0.1 5.3e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EJP62797.1 - 2.2e-12 47.0 0.0 3.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EJP62797.1 - 2.2e-09 37.4 0.0 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EJP62797.1 - 5.7e-09 36.1 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP62797.1 - 7.7e-08 32.3 0.1 1.3e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EJP62797.1 - 3.3e-07 31.0 0.0 6.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EJP62797.1 - 5.7e-05 23.4 0.0 9.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_5 PF16865.5 EJP62797.1 - 0.013 16.1 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cupin_2 PF07883.11 EJP62798.1 - 1.8e-05 24.4 0.1 3.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 EJP62798.1 - 0.042 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase MARVEL PF01284.23 EJP62799.1 - 5.1e-18 65.5 9.9 6.2e-18 65.2 9.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain 7TM_GPCR_Srx PF10328.9 EJP62799.1 - 0.01 15.5 2.7 0.013 15.2 2.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF485 PF04341.12 EJP62799.1 - 0.011 15.6 1.0 0.011 15.6 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Polysacc_synt PF01943.17 EJP62799.1 - 0.022 14.1 2.5 0.028 13.8 2.5 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Plant_vir_prot PF01307.17 EJP62799.1 - 0.051 13.8 0.4 0.4 10.9 0.0 2.4 1 1 2 3 3 3 0 Plant viral movement protein ABC2_membrane_5 PF13346.6 EJP62799.1 - 0.1 12.1 5.1 0.13 11.8 5.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_U4 PF03419.13 EJP62799.1 - 0.18 11.1 2.2 0.21 10.8 2.0 1.4 1 1 0 1 1 1 0 Sporulation factor SpoIIGA MgtE PF01769.16 EJP62799.1 - 1.4 9.3 7.5 7.7 6.9 6.8 2.0 1 1 0 1 1 1 0 Divalent cation transporter DUF2721 PF11026.8 EJP62799.1 - 2.3 8.1 6.3 5.2 7.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Collagen PF01391.18 EJP62800.1 - 0.00047 19.9 14.2 0.00047 19.9 14.2 5.1 5 0 0 5 5 5 2 Collagen triple helix repeat (20 copies) APG5 PF04106.12 EJP62801.1 - 1.5e-45 155.6 0.0 4.6e-45 154.0 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 WD40 PF00400.32 EJP62802.1 - 4.1e-23 81.2 17.6 2e-05 25.3 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP62802.1 - 4.9e-15 55.6 0.6 0.00025 21.3 0.1 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJP62802.1 - 0.00051 20.0 0.0 0.068 13.0 0.0 2.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EJP62802.1 - 0.0049 15.6 0.4 0.58 8.7 0.0 3.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Frtz PF11768.8 EJP62802.1 - 0.11 10.8 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Zn_clus PF00172.18 EJP62804.1 - 3.9e-08 33.3 12.5 6.1e-08 32.7 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UTP15_C PF09384.10 EJP62805.1 - 9e-48 161.7 0.0 1.3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EJP62805.1 - 5.2e-18 65.1 1.1 0.0002 22.1 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP62805.1 - 8.2e-09 35.6 0.1 0.0054 17.0 0.1 4.4 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EJP62805.1 - 0.016 14.5 0.2 6.3 5.9 0.2 2.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SRP-alpha_N PF04086.13 EJP62805.1 - 0.22 11.4 0.2 0.32 10.9 0.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal C2 PF00168.30 EJP62806.1 - 3e-15 56.4 0.0 4.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain GAF_2 PF13185.6 EJP62807.1 - 2.9e-07 30.9 0.0 3.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EJP62807.1 - 0.0035 18.0 0.0 0.0038 17.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain LETM1 PF07766.13 EJP62808.1 - 7.7e-10 38.6 0.2 5.2e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 LETM1-like protein SCP2 PF02036.17 EJP62809.1 - 3.7e-25 88.4 1.0 4.3e-25 88.1 1.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EJP62809.1 - 1.5e-05 25.3 0.1 1.9e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EJP62809.1 - 0.013 15.9 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain NMO PF03060.15 EJP62810.1 - 7.2e-31 107.8 3.6 6e-24 85.0 2.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EJP62810.1 - 6.9e-09 35.2 4.1 1e-08 34.6 4.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EJP62810.1 - 1.2e-08 34.4 3.6 2.8e-08 33.2 3.6 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EJP62810.1 - 2.7e-06 26.8 1.2 4.2e-06 26.1 1.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aldo_ket_red PF00248.21 EJP62811.1 - 5.8e-64 216.1 0.0 6.6e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.6 EJP62811.1 - 0.019 15.2 0.1 0.032 14.5 0.1 1.4 1 0 0 1 1 1 0 FliG middle domain Pkinase PF00069.25 EJP62812.1 - 2.3e-26 92.8 0.0 3.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62812.1 - 1.9e-13 50.3 0.0 2.4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP62812.1 - 2.6e-07 29.8 0.0 3.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EMP24_GP25L PF01105.24 EJP62813.1 - 1.9e-51 174.6 0.1 2.2e-51 174.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SANT_DAMP1_like PF16282.5 EJP62814.1 - 5.3e-30 103.5 0.3 1.1e-29 102.4 0.3 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF664 PF04978.12 EJP62814.1 - 3.3 8.1 12.4 18 5.7 0.2 4.6 4 1 1 5 5 5 0 Protein of unknown function (DUF664) Hexapep_2 PF14602.6 EJP62816.1 - 3.7e-10 39.4 12.3 3e-06 26.8 2.7 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EJP62816.1 - 5e-10 38.7 15.2 9.1e-06 25.2 3.4 3.6 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 EJP62816.1 - 6.1e-08 32.7 8.6 1.2e-07 31.7 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 EJP62816.1 - 1.7e-06 28.2 0.0 3.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase STAS_2 PF13466.6 EJP62817.1 - 0.25 11.7 2.4 1.7 9.0 0.2 2.8 3 0 0 3 3 3 0 STAS domain PPR_2 PF13041.6 EJP62818.1 - 3.9e-18 65.4 0.1 4.1e-07 30.1 0.0 5.8 6 1 1 7 7 7 3 PPR repeat family PPR_3 PF13812.6 EJP62818.1 - 1.6e-11 44.1 0.3 3.8e-06 26.9 0.0 4.0 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EJP62818.1 - 2.3e-11 43.2 0.0 0.00015 21.4 0.0 4.2 3 0 0 3 3 3 2 PPR repeat PPR PF01535.20 EJP62818.1 - 5.4e-08 32.6 0.3 1.1 9.7 0.0 6.2 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 EJP62818.1 - 2.3e-06 27.1 2.2 0.023 14.1 0.0 2.6 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP cwf18 PF08315.12 EJP62819.1 - 5.7e-46 156.5 8.2 5.7e-46 156.5 8.2 1.9 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Coa1 PF08695.10 EJP62820.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 SUZ PF12752.7 EJP62821.1 - 4e-15 56.3 5.6 4e-15 56.3 5.6 3.3 3 0 0 3 3 3 1 SUZ domain R3H PF01424.22 EJP62821.1 - 7.1e-07 29.1 0.1 1.4e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 R3H domain Glyco_transf_8 PF01501.20 EJP62821.1 - 0.27 10.8 0.0 0.49 9.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 JAB PF01398.21 EJP62822.1 - 2.2e-17 63.1 0.0 4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EJP62822.1 - 9.1e-16 58.3 0.2 2.1e-15 57.1 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function UTP25 PF06862.12 EJP62823.1 - 3.7e-189 629.4 0.0 4.7e-189 629.1 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EJP62823.1 - 0.0027 17.5 0.0 0.058 13.2 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_L17 PF01196.19 EJP62824.1 - 9.5e-31 106.6 0.0 1.8e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 Mrpl_C PF18502.1 EJP62824.1 - 0.082 13.2 0.2 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain AIM5 PF17050.5 EJP62825.1 - 4.2e-20 72.3 1.2 4.2e-20 72.3 1.2 2.9 2 1 0 2 2 2 1 Altered inheritance of mitochondria 5 DUF2514 PF10721.9 EJP62825.1 - 0.039 14.0 23.9 0.06 13.4 22.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Nefa_Nip30_N PF10187.9 EJP62825.1 - 0.82 10.0 9.9 6.7 7.1 8.2 2.7 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 vATP-synt_E PF01991.18 EJP62825.1 - 2.2 7.6 10.4 4.1 6.8 10.4 1.5 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit LDcluster4 PF18306.1 EJP62826.1 - 0.0077 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 SLOG cluster4 family AAA_17 PF13207.6 EJP62826.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 EJP62826.1 - 0.2 11.8 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase Glyco_hydro_16 PF00722.21 EJP62827.1 - 6.3e-38 130.0 0.0 6.3e-38 130.0 0.0 2.6 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 FAM196 PF15265.6 EJP62827.1 - 0.023 14.2 8.6 0.03 13.8 8.6 1.1 1 0 0 1 1 1 0 FAM196 family SOG2 PF10428.9 EJP62827.1 - 0.14 11.3 24.1 0.18 11.0 24.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RIFIN PF02009.16 EJP62827.1 - 0.55 10.1 4.7 0.8 9.5 4.7 1.3 1 0 0 1 1 1 0 Rifin ABC_tran PF00005.27 EJP62829.1 - 0.0016 19.0 0.0 0.0026 18.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TsaE PF02367.17 EJP62829.1 - 0.027 14.5 0.0 0.069 13.2 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 2OG-FeII_Oxy PF03171.20 EJP62830.1 - 6.3e-15 55.5 0.0 2.1e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EJP62830.1 - 0.0015 19.2 0.0 0.0027 18.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal FR47 PF08445.10 EJP62831.1 - 1.2e-06 28.4 0.0 2.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 EJP62831.1 - 2.3e-05 24.1 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 EJP62831.1 - 3.1e-05 24.0 0.0 6.1e-05 23.1 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP62831.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP62831.1 - 0.00012 22.4 0.0 0.00019 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP62831.1 - 0.00022 21.5 0.0 0.00031 21.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family WhiA_N PF10298.9 EJP62831.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain Acetyltransf_CG PF14542.6 EJP62831.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ketoacyl-synt PF00109.26 EJP62832.1 - 2e-71 240.6 0.0 3.5e-71 239.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EJP62832.1 - 8.7e-59 198.4 0.1 2.9e-58 196.7 0.1 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EJP62832.1 - 6.6e-53 179.9 0.8 1.3e-52 178.9 0.8 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EJP62832.1 - 1.2e-46 159.7 0.6 2e-46 159.0 0.6 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP62832.1 - 3.3e-36 123.9 0.2 9.3e-36 122.4 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EJP62832.1 - 3.7e-19 70.1 0.0 3.4e-18 67.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EJP62832.1 - 5e-18 65.7 0.0 3e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 EJP62832.1 - 5.5e-18 65.2 0.0 2.2e-17 63.3 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EJP62832.1 - 2e-13 50.8 0.0 5.2e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EJP62832.1 - 7.3e-12 45.8 0.0 3.9e-11 43.5 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP62832.1 - 3.2e-11 43.4 0.0 7.5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EJP62832.1 - 5.2e-11 42.4 0.0 1.8e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.6 EJP62832.1 - 9.2e-11 41.8 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP62832.1 - 2.8e-09 37.5 0.0 1.1e-08 35.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EJP62832.1 - 3.7e-06 26.7 0.0 1.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EJP62832.1 - 5.3e-06 26.7 0.1 2e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EJP62832.1 - 9.4e-05 21.8 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 EJP62832.1 - 0.00011 21.7 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 EJP62832.1 - 0.002 17.9 0.0 0.026 14.2 0.0 2.6 3 0 0 3 3 3 1 Lysine methyltransferase SAT PF16073.5 EJP62832.1 - 0.0034 17.2 0.7 0.032 14.0 0.7 2.2 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Transferase PF02458.15 EJP62833.1 - 4.8e-18 65.0 0.0 3.5e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 Transferase family AMP-binding PF00501.28 EJP62834.1 - 5.8e-65 219.5 0.0 7e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP62834.1 - 4e-10 40.5 0.2 9e-10 39.4 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EJP62835.1 - 4.5e-227 753.6 0.0 6.4e-77 258.9 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EJP62835.1 - 3.1e-222 738.2 0.0 2.4e-46 158.4 0.0 7.6 6 2 0 6 6 6 6 Condensation domain PP-binding PF00550.25 EJP62835.1 - 2.9e-41 139.7 3.7 1.5e-10 41.2 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP62835.1 - 2.3e-08 34.9 0.0 0.00083 20.3 0.0 4.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EJP62835.1 - 0.086 11.5 0.0 6 5.4 0.0 3.3 4 0 0 4 4 4 0 Transferase family Asparaginase_II PF06089.12 EJP62836.1 - 5.5e-120 400.2 2.4 6.9e-120 399.9 2.4 1.1 1 0 0 1 1 1 1 L-asparaginase II DUF4547 PF15080.6 EJP62836.1 - 0.076 12.7 0.0 0.9 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4547) DUF3439 PF11921.8 EJP62836.1 - 0.14 12.1 1.5 0.27 11.2 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EJP62836.1 - 0.2 9.8 3.0 0.28 9.3 3.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PQQ_3 PF13570.6 EJP62837.1 - 0.024 15.1 1.3 0.19 12.3 0.2 3.0 3 0 0 3 3 3 0 PQQ-like domain Pre-SET PF05033.16 EJP62838.1 - 3.3e-17 63.1 3.3 6.6e-17 62.1 3.3 1.5 1 0 0 1 1 1 1 Pre-SET motif SET PF00856.28 EJP62838.1 - 7.1e-17 62.3 0.0 2.9e-16 60.3 0.0 2.0 1 1 0 1 1 1 1 SET domain BTB PF00651.31 EJP62839.1 - 6.3e-10 39.3 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain F_bP_aldolase PF01116.20 EJP62840.1 - 1.8e-90 303.3 0.0 2e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Oxysterol_BP PF01237.18 EJP62841.1 - 7e-63 212.7 0.8 1.9e-60 204.7 0.8 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Cid2 PF09774.9 EJP62842.1 - 5.3e-51 173.2 0.4 6.2e-51 173.0 0.4 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.8 EJP62843.1 - 2.1e-191 637.3 32.2 1.5e-190 634.5 25.5 2.6 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EJP62843.1 - 3.6e-14 51.7 27.5 0.00048 20.0 0.2 9.9 9 1 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJP62843.1 - 8.5e-12 45.5 29.5 0.017 15.7 1.0 9.4 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EJP62843.1 - 3.7e-10 40.2 34.0 0.0024 18.4 0.1 7.4 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EJP62843.1 - 2.9e-09 36.3 25.5 0.00024 20.8 0.3 8.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJP62843.1 - 3.2e-09 36.8 10.3 0.0064 16.6 0.6 7.7 6 3 2 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJP62843.1 - 6.4e-09 35.4 13.4 2.6e-05 23.8 0.3 6.0 6 0 0 6 6 6 2 TPR repeat TPR_14 PF13428.6 EJP62843.1 - 9.5e-08 32.3 25.2 0.0067 17.2 0.1 10.1 9 2 2 11 11 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP62843.1 - 9.8e-07 28.9 20.8 0.003 17.8 1.3 5.4 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EJP62843.1 - 0.00029 20.8 26.7 0.023 14.9 0.2 8.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_4 PF07721.14 EJP62843.1 - 0.00036 20.9 5.5 2.7 8.9 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP62843.1 - 0.0015 18.8 26.9 0.17 12.2 0.4 7.7 6 3 2 8 8 8 2 Tetratricopeptide repeat DUF3922 PF13059.6 EJP62843.1 - 0.0026 18.2 0.6 0.06 13.8 0.7 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3992) TPR_3 PF07720.12 EJP62843.1 - 0.012 15.6 0.3 0.6 10.2 0.3 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EJP62843.1 - 0.14 12.6 16.2 1.5 9.3 0.0 7.8 9 0 0 9 9 7 0 Tetratricopeptide repeat BTAD PF03704.17 EJP62843.1 - 2.7 8.4 14.2 1.2 9.6 0.4 3.9 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EJP62843.1 - 3.1 8.6 23.3 31 5.5 0.6 8.3 9 0 0 9 9 7 0 Tetratricopeptide repeat DAGK_cat PF00781.24 EJP62844.1 - 1.5e-26 92.4 0.0 2.4e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BCS1_N PF08740.11 EJP62845.1 - 1.7e-42 145.5 0.0 2.5e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EJP62845.1 - 7.6e-16 58.7 0.0 1.2e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EJP62845.1 - 0.00024 20.7 0.0 0.0064 16.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 EJP62845.1 - 0.00051 19.6 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EJP62845.1 - 0.0047 16.9 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EJP62845.1 - 0.0062 16.9 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EJP62845.1 - 0.0078 16.1 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.13 EJP62845.1 - 0.013 14.7 0.0 0.033 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 EJP62845.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EJP62845.1 - 0.028 14.7 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJP62845.1 - 0.031 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EJP62845.1 - 0.033 14.3 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJP62845.1 - 0.044 14.3 0.0 0.078 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EJP62845.1 - 0.051 14.1 0.0 0.094 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 EJP62845.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RNA_helicase PF00910.22 EJP62845.1 - 0.13 12.7 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 EJP62845.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EJP62845.1 - 0.21 12.0 0.1 0.74 10.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain AA_permease PF00324.21 EJP62846.1 - 5.7e-116 387.9 43.0 7e-116 387.6 43.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP62846.1 - 6.9e-27 94.3 48.9 9.5e-27 93.9 48.9 1.1 1 0 0 1 1 1 1 Amino acid permease VPS9 PF02204.18 EJP62847.1 - 4.7e-20 71.7 0.1 1.8e-19 69.9 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EJP62847.1 - 1.6e-19 69.7 2.1 4.3e-15 55.6 0.0 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP62847.1 - 3.5e-15 56.3 0.1 3.7e-07 30.7 0.0 3.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP62847.1 - 6.7e-09 35.3 0.6 0.32 11.7 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EJP62847.1 - 1.8e-08 34.8 0.4 0.19 12.3 0.0 5.5 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EJP62847.1 - 4.8e-06 26.8 1.2 1.3 9.6 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat PX PF00787.24 EJP62847.1 - 9.6e-05 22.3 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 PX domain DUF3035 PF11233.8 EJP62847.1 - 0.26 11.6 3.7 0.16 12.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) YchF-GTPase_C PF06071.13 EJP62849.1 - 2.7e-34 117.2 0.3 7.9e-34 115.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EJP62849.1 - 6.7e-16 58.4 0.0 1.7e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJP62849.1 - 0.00041 19.9 0.0 0.00083 18.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EJP62849.1 - 0.00057 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain PPAK PF02818.15 EJP62849.1 - 0.0052 16.9 1.1 0.016 15.3 1.1 1.9 1 0 0 1 1 1 1 PPAK motif AKAP95 PF04988.12 EJP62849.1 - 0.027 14.7 0.3 0.054 13.7 0.3 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) BetaGal_dom3 PF13363.6 EJP62849.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_14 PF13173.6 EJP62849.1 - 0.11 12.5 0.0 0.43 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EJP62849.1 - 5.3 7.5 8.2 30 5.0 8.2 2.2 1 1 0 1 1 1 0 AAA domain Peptidase_C97 PF05903.14 EJP62850.1 - 1.4e-28 99.7 0.0 2e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Ribosomal_S11 PF00411.19 EJP62851.1 - 3.3e-12 46.8 0.0 5.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 EJP62852.1 - 1e-36 126.2 0.2 3.7e-36 124.5 0.1 2.0 2 0 0 2 2 2 1 Tim44-like domain DUF1768 PF08719.11 EJP62853.1 - 3.7e-46 157.3 0.1 1.4e-44 152.2 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Sugar_tr PF00083.24 EJP62854.1 - 3.3e-75 253.7 20.0 3.8e-75 253.5 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP62854.1 - 4.6e-14 52.1 37.1 3.8e-09 35.9 15.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.14 EJP62855.1 - 2.7e-13 49.9 0.1 4.9e-13 49.0 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Metallophos PF00149.28 EJP62856.1 - 3.7e-10 40.6 1.1 7.9e-10 39.6 1.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sulfatase PF00884.23 EJP62857.1 - 4.1e-07 29.7 0.4 1.6e-06 27.8 0.3 1.9 1 1 0 1 1 1 1 Sulfatase Regnase_1_C PF18561.1 EJP62857.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Phosphodiest PF01663.22 EJP62857.1 - 0.056 13.0 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1106 PF06523.11 EJP62857.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Ninjurin PF04923.12 EJP62858.1 - 0.082 12.8 0.1 0.082 12.8 0.1 2.7 1 1 2 3 3 3 0 Ninjurin Pox_A14 PF05767.12 EJP62858.1 - 0.13 12.5 0.4 0.13 12.5 0.4 2.4 2 2 0 2 2 2 0 Poxvirus virion envelope protein A14 MARVEL PF01284.23 EJP62858.1 - 1.1 9.2 8.4 1.6 8.8 8.4 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF1304 PF06993.12 EJP62858.1 - 8.1 6.5 10.6 1.8 8.6 3.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1304) AMP-binding PF00501.28 EJP62859.1 - 2.9e-63 214.0 0.0 3.9e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EJP62859.1 - 1e-16 60.7 0.0 1.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 EJP62859.1 - 2e-10 41.5 0.8 5.7e-10 40.0 0.8 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 EJP62859.1 - 0.054 13.9 0.1 0.21 12.0 0.1 2.1 1 0 0 1 1 1 0 Phosphopantetheine attachment site Peptidase_M14 PF00246.24 EJP62860.1 - 1.6e-77 261.2 0.0 2e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EJP62860.1 - 3e-10 40.3 0.0 1.8e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase activation peptide DOPA_dioxygen PF08883.11 EJP62861.1 - 4.7e-42 142.5 0.1 5.8e-42 142.2 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family 2OG-FeII_Oxy PF03171.20 EJP62862.1 - 6.2e-13 49.1 0.0 1.2e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EJP62862.1 - 2.5e-10 41.2 0.0 4.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_M20 PF01546.28 EJP62864.1 - 3.9e-07 30.0 0.0 6.1e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJP62864.1 - 0.00016 21.5 0.1 0.00033 20.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Amidohydro_2 PF04909.14 EJP62865.1 - 1.7e-46 159.4 1.3 2e-46 159.1 1.3 1.1 1 0 0 1 1 1 1 Amidohydrolase 5_nucleotid_C PF02872.18 EJP62866.1 - 4.5e-36 124.4 0.0 7.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EJP62866.1 - 0.035 14.6 0.1 0.081 13.4 0.1 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase KKLCAg1 PF15204.6 EJP62867.1 - 1.6 8.9 8.5 53 4.0 0.8 4.0 1 1 3 4 4 4 0 Kita-kyushu lung cancer antigen 1 DUF3431 PF11913.8 EJP62868.1 - 9e-66 221.7 0.0 1.2e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4096 PF13340.6 EJP62868.1 - 0.018 15.2 0.0 0.061 13.5 0.0 1.9 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Fungal_trans_2 PF11951.8 EJP62869.1 - 1.1e-12 47.5 0.0 1.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP62869.1 - 2.2e-08 34.1 14.1 4.3e-07 29.9 10.6 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 EJP62870.1 - 2e-52 178.5 51.1 2.5e-52 178.2 51.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP62870.1 - 1.8e-33 115.9 35.4 1.8e-33 115.9 35.4 1.6 2 0 0 2 2 2 1 Amino acid permease AGTRAP PF06396.11 EJP62871.1 - 2.2 8.1 7.9 0.53 10.1 2.0 2.6 1 1 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) PAN_4 PF14295.6 EJP62872.1 - 0.0017 18.2 0.5 0.0043 16.9 0.5 1.7 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 EJP62872.1 - 0.017 14.5 0.0 0.039 13.4 0.0 1.5 1 1 0 1 1 1 0 Fringe-like DUF4185 PF13810.6 EJP62873.1 - 2.2e-05 23.8 0.1 3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) MIOX PF05153.15 EJP62874.1 - 5.9e-119 396.2 0.0 7.3e-119 395.9 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase NOG1_N PF17835.1 EJP62874.1 - 0.22 11.5 1.3 3.1 7.7 0.1 2.6 2 1 1 3 3 3 0 NOG1 N-terminal helical domain TFR_dimer PF04253.15 EJP62875.1 - 4.1e-31 107.6 0.0 8e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EJP62875.1 - 8.8e-14 51.6 0.0 2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EJP62875.1 - 3.7e-09 36.5 0.1 8.2e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 PA domain Vps35 PF03635.17 EJP62876.1 - 0 1013.3 2.3 0 1013.1 2.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RIH_assoc PF08454.11 EJP62876.1 - 0.27 11.1 3.2 7.7 6.4 0.2 3.6 3 0 0 3 3 3 0 RyR and IP3R Homology associated Dfp1_Him1_M PF08630.10 EJP62876.1 - 1.7 8.9 6.5 0.95 9.7 0.2 3.0 3 0 0 3 3 3 0 Dfp1/Him1, central region Amidohydro_2 PF04909.14 EJP62877.1 - 6e-17 62.4 0.0 8.6e-16 58.6 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Cyt-b5 PF00173.28 EJP62878.1 - 8.8e-14 51.4 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SRAP PF02586.14 EJP62879.1 - 5.3e-78 261.5 0.0 6.9e-78 261.2 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Trp_oprn_chp PF09534.10 EJP62881.1 - 0.035 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF937 PF06078.11 EJP62881.1 - 0.16 12.6 0.2 2.9 8.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF937) DUF4235 PF14019.6 EJP62881.1 - 0.21 11.7 5.3 4.6 7.4 5.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) PT-VENN PF04829.13 EJP62881.1 - 0.73 10.0 8.8 5.1 7.2 0.2 2.5 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Rick_17kDa_Anti PF05433.15 EJP62881.1 - 3.2 7.7 23.4 0.24 11.3 1.1 2.7 3 0 0 3 3 3 0 Glycine zipper 2TM domain MFS_1 PF07690.16 EJP62882.1 - 2.5e-41 141.8 61.2 3.6e-32 111.7 31.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 EJP62882.1 - 2e-18 66.4 15.4 2.7e-07 31.2 0.3 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat MFS_2 PF13347.6 EJP62882.1 - 0.00013 20.7 13.6 0.028 13.0 0.1 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Ge1_WD40 PF16529.5 EJP62882.1 - 0.012 14.6 0.1 1.2 8.0 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Spore_YabQ PF09578.10 EJP62882.1 - 7.1 6.9 11.1 2.5 8.4 0.8 2.8 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Transket_pyr PF02779.24 EJP62883.1 - 7.8e-62 208.1 0.0 1.2e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EJP62883.1 - 3.3e-57 193.7 0.0 4.8e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EJP62883.1 - 2.1e-54 183.4 0.1 3.4e-54 182.7 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EJP62883.1 - 1.2e-19 69.6 0.4 2.6e-19 68.5 0.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus BSD PF03909.17 EJP62884.1 - 6.1e-30 103.0 0.8 1.6e-13 50.5 0.1 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 EJP62884.1 - 2.5e-25 88.6 0.0 6.7e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain VAPB_antitox PF02697.14 EJP62884.1 - 0.24 12.2 2.0 0.49 11.2 0.1 2.4 3 0 0 3 3 3 0 Putative antitoxin AAA PF00004.29 EJP62885.1 - 6.7e-38 130.1 0.0 3.4e-37 127.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP62885.1 - 1.8e-08 34.1 0.0 4.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EJP62885.1 - 8.3e-06 25.6 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EJP62885.1 - 5.8e-05 23.4 0.1 0.051 13.9 0.1 2.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP62885.1 - 6.7e-05 23.3 0.0 0.004 17.5 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EJP62885.1 - 0.00022 21.3 0.0 0.00097 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EJP62885.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EJP62885.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EJP62885.1 - 0.007 15.8 0.1 0.021 14.2 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EJP62885.1 - 0.009 15.8 0.1 0.03 14.1 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 EJP62885.1 - 0.0093 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP62885.1 - 0.012 16.2 0.0 0.051 14.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EJP62885.1 - 0.024 13.9 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain TniB PF05621.11 EJP62885.1 - 0.026 13.9 0.0 0.44 9.9 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 EJP62885.1 - 0.047 14.1 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EJP62885.1 - 0.065 12.8 0.1 0.76 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EJP62885.1 - 0.1 11.8 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2992 PF11208.8 EJP62885.1 - 0.13 12.5 0.0 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) AAA_28 PF13521.6 EJP62885.1 - 0.15 12.3 0.2 0.53 10.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EJP62885.1 - 0.15 12.0 0.1 0.46 10.4 0.1 1.8 1 0 0 1 1 1 0 NACHT domain Zn_clus PF00172.18 EJP62886.1 - 0.0034 17.4 4.3 0.0083 16.2 4.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TYA PF01021.19 EJP62886.1 - 0.45 10.9 5.0 1.2 9.5 3.8 2.4 2 1 1 3 3 3 0 TYA transposon protein ATP-synt_ab PF00006.25 EJP62887.1 - 2.9e-62 210.1 0.0 4.8e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EJP62887.1 - 1.1e-23 83.6 1.1 2.9e-23 82.2 0.3 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 EJP62887.1 - 0.012 16.0 0.0 0.34 11.3 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EJP62887.1 - 0.014 15.3 0.4 0.035 14.0 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 EJP62887.1 - 0.017 14.3 0.3 0.082 12.1 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 EJP62887.1 - 0.031 13.6 0.2 0.058 12.7 0.2 1.5 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 EJP62887.1 - 0.036 14.0 0.0 0.084 12.8 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EJP62887.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain T3SS_ATPase_C PF18269.1 EJP62887.1 - 0.059 13.2 0.5 0.31 10.9 0.5 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 EJP62887.1 - 0.06 13.7 0.7 0.48 10.8 0.2 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJP62887.1 - 0.07 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Alpha-amylase_C PF02806.18 EJP62888.1 - 2e-26 92.3 0.1 4.9e-26 91.0 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 EJP62888.1 - 2.3e-15 57.0 1.0 1.2e-11 44.8 0.3 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 EJP62888.1 - 1.5e-14 54.1 0.0 5.8e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.6 EJP62888.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain AAA_2 PF07724.14 EJP62889.1 - 4.5e-33 114.8 0.0 8.8e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EJP62889.1 - 6.4e-13 49.3 0.0 1.2e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EJP62889.1 - 4.6e-08 33.0 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EJP62889.1 - 4.7e-07 29.9 0.0 1.5e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EJP62889.1 - 3.1e-05 24.3 1.1 0.00038 20.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain MCM PF00493.23 EJP62889.1 - 9.7e-05 21.6 0.0 0.0002 20.5 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 EJP62889.1 - 0.0015 19.0 0.1 0.0056 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EJP62889.1 - 0.0027 17.3 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EJP62889.1 - 0.0038 17.2 0.0 0.0081 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EJP62889.1 - 0.0079 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 EJP62889.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EJP62889.1 - 0.038 14.5 0.2 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EJP62889.1 - 0.04 13.3 0.0 0.42 10.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 EJP62889.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EJP62889.1 - 0.12 12.8 0.5 0.25 11.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter RuvB_N PF05496.12 EJP62889.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EJP62889.1 - 0.16 11.9 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 EJP62889.1 - 0.17 12.3 0.1 0.47 10.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain COX4 PF02936.14 EJP62890.1 - 1.5e-46 157.9 0.1 1.7e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Zn_clus PF00172.18 EJP62891.1 - 7.9e-05 22.7 12.5 0.00015 21.8 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP62891.1 - 0.0082 15.2 0.3 0.013 14.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF679 PF05078.12 EJP62891.1 - 0.077 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF679) Gag_MA PF01140.19 EJP62891.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Matrix protein (MA), p15 Mus7 PF09462.10 EJP62893.1 - 9.7e-121 404.6 0.0 1.4e-120 404.0 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family MMS22L_N PF14910.6 EJP62893.1 - 0.0047 15.4 0.0 0.05 12.0 0.0 2.0 1 1 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal CCDC53 PF10152.9 EJP62893.1 - 0.036 14.5 0.1 0.036 14.5 0.1 3.6 4 0 0 4 4 4 0 Subunit CCDC53 of WASH complex ORC5_C PF14630.6 EJP62894.1 - 1.1e-89 300.8 0.0 1.5e-89 300.3 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EJP62894.1 - 4.5e-14 53.2 0.1 1e-13 52.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP62894.1 - 0.024 14.9 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPT PF03151.16 EJP62895.1 - 2.6e-59 201.0 13.1 3.1e-59 200.7 13.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EJP62895.1 - 4.9e-11 43.0 31.6 1.3e-05 25.4 12.4 3.2 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EJP62895.1 - 9.4e-06 25.0 16.4 6.3e-05 22.3 16.4 2.0 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EJP62895.1 - 5e-05 22.7 8.1 6.1e-05 22.4 7.5 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 EJP62895.1 - 0.012 14.8 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Nucleotide-sugar transporter RRM_1 PF00076.22 EJP62896.1 - 9.9e-60 198.3 0.0 9.8e-21 73.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJP62896.1 - 8.5e-10 38.3 0.0 1.2e-05 24.9 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJP62896.1 - 1.8e-08 34.1 0.0 0.022 14.6 0.0 3.3 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EJP62896.1 - 4.2e-05 23.5 0.1 0.39 10.7 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 EJP62896.1 - 0.00015 21.7 0.0 0.29 11.2 0.0 2.7 3 0 0 3 3 3 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 EJP62896.1 - 0.00067 19.7 0.2 0.68 10.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 EJP62896.1 - 0.025 14.6 0.0 6.7 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain RRM_8 PF11835.8 EJP62896.1 - 0.057 13.6 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 RRM-like domain Pkinase PF00069.25 EJP62897.1 - 1.7e-49 168.6 0.1 9.1e-49 166.2 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62897.1 - 1.8e-23 83.1 0.0 3.6e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP62897.1 - 0.00032 20.7 2.2 0.00033 20.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EJP62897.1 - 0.0029 17.2 0.2 0.0073 15.9 0.2 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EJP62897.1 - 0.62 9.6 2.3 0.39 10.3 0.2 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.22 EJP62898.1 - 0.04 13.7 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPR_2 PF13041.6 EJP62899.1 - 3.6e-24 84.7 1.2 6.6e-16 58.2 0.0 4.7 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 EJP62899.1 - 2e-09 37.4 0.7 0.0041 17.2 0.0 3.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EJP62899.1 - 4.2e-07 29.5 0.2 2.3e-06 27.1 0.1 2.2 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EJP62899.1 - 1.9e-06 27.7 0.0 0.037 14.3 0.0 4.2 3 1 0 3 3 3 2 PPR repeat PPR_1 PF12854.7 EJP62899.1 - 0.018 14.7 3.9 9.7 6.0 0.0 5.2 6 1 0 6 6 6 0 PPR repeat DUF5611 PF18446.1 EJP62900.1 - 0.059 14.2 0.8 0.059 14.2 0.8 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5611) DNA_pol_B PF00136.21 EJP62901.1 - 1.2e-113 380.3 0.0 2e-113 379.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EJP62901.1 - 5.3e-69 231.7 0.1 1e-68 230.8 0.1 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EJP62901.1 - 1.9e-40 139.1 0.0 3.2e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EJP62901.1 - 4.1e-25 87.6 13.9 4.5e-25 87.5 9.4 3.0 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EJP62901.1 - 0.028 13.3 0.1 0.35 9.7 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral NUP50 PF08911.11 EJP62901.1 - 0.13 13.0 2.4 0.29 11.8 0.5 2.6 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) MIF4G PF02854.19 EJP62902.1 - 1.4e-51 175.1 0.0 2.4e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EJP62902.1 - 2e-23 82.4 0.7 6.8e-23 80.6 0.7 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Asp-B-Hydro_N PF05279.11 EJP62902.1 - 0.074 13.1 33.3 0.21 11.6 33.3 1.7 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Aquarius_N PF16399.5 EJP62903.1 - 0 1043.1 0.6 3.2e-239 796.1 0.0 2.1 1 1 1 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EJP62903.1 - 4.5e-26 91.7 0.0 7.9e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EJP62903.1 - 1.4e-21 77.5 0.0 5.8e-21 75.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP62903.1 - 3.7e-07 30.1 0.0 0.00086 19.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EJP62903.1 - 1.8e-05 25.1 0.0 5.2e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EJP62903.1 - 1.9e-05 24.7 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EJP62903.1 - 0.00028 21.3 0.5 0.0014 19.0 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 EJP62903.1 - 0.0042 16.4 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 EJP62903.1 - 0.0082 16.6 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EJP62903.1 - 0.027 14.2 0.0 0.081 12.7 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 EJP62903.1 - 0.032 14.0 0.3 1.4 8.6 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EJP62903.1 - 0.033 14.5 0.4 0.22 11.8 0.3 2.3 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EJP62903.1 - 0.037 13.3 0.9 0.05 12.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EJP62903.1 - 0.076 13.0 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) RepB-RCR_reg PF10723.9 EJP62903.1 - 0.1 12.6 0.2 0.33 10.9 0.2 1.8 1 0 0 1 1 1 0 Replication regulatory protein RepB AAA_25 PF13481.6 EJP62903.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 EJP62903.1 - 0.18 10.9 0.0 14 4.7 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase efThoc1 PF11957.8 EJP62904.1 - 1.3e-137 459.5 0.1 1.8e-137 459.0 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 EJP62904.1 - 5.3e-20 71.9 0.0 1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase eIF-5_eIF-2B PF01873.17 EJP62905.1 - 1.8e-39 134.3 0.1 5.1e-39 132.8 0.0 1.8 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 EJP62905.1 - 6.1e-23 80.8 1.5 2.3e-22 78.9 0.4 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon OAD_gamma PF04277.13 EJP62905.1 - 1.2 9.7 2.8 0.84 10.3 0.1 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain p450 PF00067.22 EJP62906.1 - 6.8e-36 124.0 0.0 1.4e-35 122.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 TPT PF03151.16 EJP62907.1 - 1.6e-28 99.9 24.3 2.2e-28 99.4 24.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EJP62907.1 - 0.0011 19.1 40.3 0.0079 16.4 17.2 2.4 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 EJP62907.1 - 0.0053 16.0 26.0 0.049 12.8 26.0 2.0 1 1 0 1 1 1 1 UAA transporter family CdvA PF18822.1 EJP62908.1 - 0.0096 15.7 0.3 0.028 14.3 0.3 1.7 1 0 0 1 1 1 1 CdvA-like coiled-coil domain eIF-6 PF01912.18 EJP62909.1 - 4.2e-81 271.0 0.6 5.7e-81 270.6 0.6 1.2 1 0 0 1 1 1 1 eIF-6 family HupE_UreJ PF04955.12 EJP62909.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 HupE / UreJ protein Methyltransf_31 PF13847.6 EJP62910.1 - 1.3e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP62910.1 - 3.1e-07 31.0 0.0 5.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP62910.1 - 2.9e-06 27.9 0.0 5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP62910.1 - 5.6e-06 26.3 0.0 7.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP62910.1 - 5.3e-05 23.8 0.0 0.00011 22.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP62910.1 - 0.00067 19.2 0.0 0.00098 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain AdoMet_MTase PF07757.13 EJP62910.1 - 0.004 17.5 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EJP62910.1 - 0.023 14.7 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EJP62910.1 - 0.044 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HEAT PF02985.22 EJP62911.1 - 4.9e-39 129.0 13.3 0.015 15.5 0.1 13.0 14 0 0 14 14 13 11 HEAT repeat HEAT_2 PF13646.6 EJP62911.1 - 2.1e-32 111.4 5.5 4e-09 36.7 0.0 8.1 4 2 5 9 9 9 8 HEAT repeats HEAT_EZ PF13513.6 EJP62911.1 - 4.2e-12 46.3 7.2 0.033 14.7 0.0 8.2 8 2 2 10 10 10 2 HEAT-like repeat Cnd1 PF12717.7 EJP62911.1 - 1.2e-10 41.6 10.7 0.00064 19.8 0.3 5.9 6 1 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EJP62911.1 - 2.3e-10 40.9 4.0 0.023 15.3 0.1 7.1 5 2 4 9 9 9 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EJP62911.1 - 3.5e-06 25.9 10.5 0.0055 15.3 0.2 5.0 3 1 2 5 5 5 2 Adaptin N terminal region RTP1_C1 PF10363.9 EJP62911.1 - 0.00018 21.7 5.7 0.21 11.8 0.1 5.0 4 1 1 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EJP62911.1 - 0.0013 18.4 4.3 5.7 6.4 0.1 4.3 3 2 1 4 4 4 2 CLASP N terminal M11L PF11099.8 EJP62911.1 - 0.0039 17.5 1.4 1.5 9.1 0.0 3.5 3 1 1 4 4 4 1 Apoptosis regulator M11L like Ecm29 PF13001.7 EJP62911.1 - 0.014 14.1 0.5 2 7.0 0.1 2.9 2 1 0 2 2 2 0 Proteasome stabiliser Arm PF00514.23 EJP62911.1 - 0.32 11.1 2.0 3.1 8.0 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 EJP62911.1 - 0.45 9.3 1.9 4.9 5.9 0.2 3.2 3 1 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Proteasom_PSMB PF10508.9 EJP62911.1 - 1.1 7.7 5.1 9.4 4.6 0.0 2.5 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit tRNA_synthFbeta PF17759.1 EJP62912.1 - 1.6e-47 161.7 0.0 2.4e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EJP62912.1 - 2.9e-33 113.9 0.4 4.7e-32 110.0 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EJP62912.1 - 4.4e-24 85.1 0.0 7.2e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EJP62912.1 - 1.9e-17 63.3 0.0 2.7e-14 53.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain SPRY PF00622.28 EJP62912.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 SPRY domain Myotub-related PF06602.14 EJP62913.1 - 1e-148 495.0 0.1 1.2e-148 494.7 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.20 EJP62914.1 - 6.6e-24 84.2 0.1 3.7e-23 81.8 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EJP62914.1 - 2.5e-12 46.4 0.1 4.2e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EJP62914.1 - 0.097 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 EJP62914.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Coilin N-terminus Mg_trans_NIPA PF05653.14 EJP62915.1 - 7.6e-103 343.7 14.7 8.9e-103 343.4 14.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EJP62915.1 - 2.4e-05 24.5 5.9 2.4e-05 24.5 5.9 3.8 3 1 0 3 3 3 2 EamA-like transporter family DUF3328 PF11807.8 EJP62916.1 - 4.5e-46 157.4 0.1 5.4e-46 157.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2420 PF10336.9 EJP62918.1 - 8.2e-13 48.3 0.4 1.4e-12 47.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Pkinase_C PF00433.24 EJP62918.1 - 0.2 12.4 6.6 1.3 9.8 0.0 3.8 3 1 0 3 3 3 0 Protein kinase C terminal domain Adap_comp_sub PF00928.21 EJP62919.1 - 4.7e-18 65.5 0.1 6.5e-18 65.0 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EJP62919.1 - 3.2e-08 33.6 0.0 5.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EJP62919.1 - 0.0018 18.7 0.2 0.0035 17.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) ANAPC4 PF12896.7 EJP62920.1 - 3.5e-69 232.4 0.0 5.4e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EJP62920.1 - 1.3e-11 44.6 0.0 8.2e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain He_PIG_assoc PF10632.9 EJP62920.1 - 0.13 12.0 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Gtr1_RagA PF04670.12 EJP62921.1 - 3.9e-70 235.8 0.1 4.9e-70 235.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EJP62921.1 - 0.0013 18.3 0.0 0.0042 16.6 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 EJP62921.1 - 0.0095 16.1 0.0 0.021 15.0 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EJP62921.1 - 0.032 14.6 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 EJP62921.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJP62921.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF3341 PF11821.8 EJP62922.1 - 0.21 11.2 2.2 0.73 9.5 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3341) Podoplanin PF05808.11 EJP62923.1 - 1.2e-05 25.4 0.3 1.9e-05 24.8 0.3 1.2 1 0 0 1 1 1 1 Podoplanin CD99L2 PF12301.8 EJP62923.1 - 0.0012 19.1 0.1 0.0023 18.2 0.1 1.4 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF347 PF03988.12 EJP62923.1 - 0.026 14.7 0.4 0.041 14.1 0.4 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Amnionless PF14828.6 EJP62923.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4366 PF14283.6 EJP62923.1 - 0.19 11.8 0.0 0.41 10.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Phage_holin_2_4 PF16082.5 EJP62923.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like PepSY_TM PF03929.16 EJP62923.1 - 0.26 10.9 1.3 0.41 10.3 0.9 1.5 1 1 0 1 1 1 0 PepSY-associated TM region Pneumo_att_G PF05539.11 EJP62923.1 - 3.3 7.2 16.6 4.7 6.7 16.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Pkinase PF00069.25 EJP62924.1 - 2.5e-43 148.4 0.0 3.9e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62924.1 - 9.3e-24 84.1 0.0 1.4e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP62924.1 - 5.1e-05 22.7 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FlxA PF14282.6 EJP62925.1 - 0.32 11.0 5.5 3 7.9 0.0 2.6 2 0 0 2 2 2 0 FlxA-like protein TauD PF02668.16 EJP62926.1 - 1.3e-32 113.6 0.1 2.2e-32 112.9 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EJP62926.1 - 0.0094 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 CsiD TilS PF09179.11 EJP62926.1 - 0.011 16.2 1.4 0.076 13.5 0.6 2.3 2 0 0 2 2 2 0 TilS substrate binding domain Mg_trans_NIPA PF05653.14 EJP62927.1 - 7.2e-90 301.1 22.8 9.4e-90 300.7 22.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EJP62927.1 - 4.5e-05 23.6 7.6 4.5e-05 23.6 7.6 3.3 3 0 0 3 3 3 1 EamA-like transporter family ST7 PF04184.12 EJP62927.1 - 0.68 8.3 3.0 1.2 7.6 3.0 1.2 1 0 0 1 1 1 0 ST7 protein DUF805 PF05656.14 EJP62927.1 - 1.2 9.6 15.4 0.75 10.2 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF805) U-box PF04564.15 EJP62928.1 - 2.2e-17 63.0 0.0 3.8e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.6 EJP62928.1 - 3.2e-05 23.5 0.1 7.1e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 TPR repeat CHIP_TPR_N PF18391.1 EJP62928.1 - 5.9e-05 23.8 8.2 9.9e-05 23.0 8.2 1.3 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_2 PF07719.17 EJP62928.1 - 0.00047 20.1 2.8 0.0064 16.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP62928.1 - 0.0037 17.0 0.0 0.5 10.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP62928.1 - 0.0044 17.6 0.0 0.0044 17.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP62928.1 - 0.0082 16.6 0.0 0.0082 16.6 0.0 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EJP62928.1 - 0.072 13.5 0.3 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_N PF08240.12 EJP62930.1 - 1.6e-22 79.5 0.1 3e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP62930.1 - 2.8e-21 75.8 0.3 5.3e-21 75.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP62930.1 - 5.7e-06 27.4 0.0 1.1e-05 26.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 EJP62930.1 - 0.37 11.0 1.5 1.6 8.9 0.3 2.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal p450 PF00067.22 EJP62931.1 - 2.3e-50 171.7 0.0 3.9e-50 170.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 4HBT PF03061.22 EJP62932.1 - 2.8e-06 27.6 0.1 5.1e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF3710 PF12502.8 EJP62932.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) IMUP PF15761.5 EJP62932.1 - 0.23 12.2 4.5 0.35 11.6 4.5 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EJP62932.1 - 5 6.7 12.6 7.3 6.1 12.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CoaE PF01121.20 EJP62934.1 - 2.5e-41 141.3 0.0 7.9e-41 139.7 0.0 1.7 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EJP62934.1 - 0.015 15.9 0.3 0.23 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sds3 PF08598.11 EJP62935.1 - 0.063 13.3 5.3 0.029 14.4 3.0 1.6 2 0 0 2 2 2 0 Sds3-like DUF5320 PF17253.2 EJP62935.1 - 0.96 10.6 12.6 4.3 8.5 4.6 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5320) ThiF PF00899.21 EJP62936.1 - 2.9e-26 92.3 0.0 4.4e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Imp-YgjV PF10688.9 EJP62938.1 - 4.6 7.0 12.0 0.061 13.1 1.0 2.7 3 0 0 3 3 3 0 Bacterial inner membrane protein Jnk-SapK_ap_N PF09744.9 EJP62939.1 - 4.8e-05 23.6 4.3 9.1e-05 22.7 4.3 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Herpes_UL25 PF01499.16 EJP62939.1 - 0.031 12.8 0.6 0.046 12.3 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family AP1AR PF15745.5 EJP62939.1 - 0.052 13.2 3.9 0.088 12.4 3.9 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein ZapB PF06005.12 EJP62939.1 - 0.13 12.7 4.6 29 5.2 0.2 3.2 2 1 1 3 3 3 0 Cell division protein ZapB Cnn_1N PF07989.11 EJP62939.1 - 0.21 11.7 1.8 1.2 9.3 0.0 2.7 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 NDUF_B12 PF08122.12 EJP62940.1 - 3.5e-19 68.6 1.1 1.7e-17 63.2 0.1 2.3 2 0 0 2 2 2 2 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.20 EJP62941.1 - 3.3e-24 85.7 0.0 2.2e-11 43.5 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 EJP62941.1 - 0.2 12.3 0.0 0.46 11.1 0.0 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain CLTH PF10607.9 EJP62942.1 - 3.1e-34 118.0 0.0 4.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EJP62942.1 - 2.3e-05 24.2 0.1 5.8e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 LisH HLH PF00010.26 EJP62943.1 - 1.1e-12 47.7 0.3 2.4e-12 46.6 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA_28 PF13521.6 EJP62943.1 - 0.21 11.8 3.8 0.12 12.6 1.2 2.0 2 0 0 2 2 2 0 AAA domain GIT1_C PF12205.8 EJP62943.1 - 2.9 8.0 9.0 0.43 10.7 2.3 2.7 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF2841 PF11001.8 EJP62944.1 - 1.4e-43 147.9 0.8 2.1e-43 147.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Sec34 PF04136.15 EJP62944.1 - 0.1 12.5 0.1 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 Sec34-like family ABC_membrane PF00664.23 EJP62946.1 - 2.2e-84 283.4 29.2 1.4e-46 159.4 4.4 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP62946.1 - 1.3e-48 165.0 0.0 6.1e-28 98.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP62946.1 - 1.7e-10 40.7 2.6 0.0081 15.6 0.2 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 EJP62946.1 - 3.1e-08 33.4 3.1 7.2e-08 32.2 3.1 1.5 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region MMR_HSR1 PF01926.23 EJP62946.1 - 1.4e-05 25.2 0.5 0.27 11.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP62946.1 - 0.00025 21.0 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EJP62946.1 - 0.0022 18.1 1.2 0.16 12.0 0.1 2.6 2 0 0 2 2 2 1 Dynamin family UPF0093 PF03653.13 EJP62946.1 - 0.0023 18.2 0.4 0.0076 16.5 0.4 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) AAA_16 PF13191.6 EJP62946.1 - 0.0047 17.3 0.6 0.26 11.6 0.1 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_23 PF13476.6 EJP62946.1 - 0.0078 16.7 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EJP62946.1 - 0.0087 15.8 0.8 3.1 7.6 0.0 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EJP62946.1 - 0.032 14.0 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 EJP62946.1 - 0.037 13.7 0.1 2.4 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EJP62946.1 - 0.041 14.0 0.6 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 EJP62946.1 - 0.079 12.8 0.5 12 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 EJP62946.1 - 0.094 13.1 0.0 9 6.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_22 PF13401.6 EJP62946.1 - 0.12 12.6 0.3 50 4.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EJP62946.1 - 0.16 11.6 0.2 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MWFE PF15879.5 EJP62946.1 - 0.17 12.1 2.3 0.31 11.2 0.2 2.7 2 0 0 2 2 1 0 NADH-ubiquinone oxidoreductase MWFE subunit NACHT PF05729.12 EJP62946.1 - 0.2 11.6 0.7 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.16 EJP62946.1 - 0.29 10.4 1.3 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 AIG1 family DUF1749 PF08538.10 EJP62947.1 - 8.7e-78 261.4 0.0 9.7e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EJP62947.1 - 7.7e-09 36.5 0.1 9e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP62947.1 - 9.3e-08 32.0 0.0 0.00094 18.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP62947.1 - 3.1e-07 29.9 0.0 8.6e-06 25.2 0.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EJP62947.1 - 0.004 16.7 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 EJP62947.1 - 0.005 16.7 0.0 0.052 13.4 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase NUDIX PF00293.28 EJP62949.1 - 4.5e-16 59.1 0.1 9.6e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EJP62949.1 - 1.7e-12 47.9 0.3 4.1e-12 46.6 0.3 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EJP62949.1 - 2e-07 30.5 0.6 3.7e-07 29.7 0.6 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PQ-loop PF04193.14 EJP62950.1 - 1.4e-37 127.3 11.1 5.1e-19 67.8 0.6 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EJP62950.1 - 0.41 11.5 4.1 4.4 8.1 0.1 2.6 3 0 0 3 3 3 0 ER lumen protein retaining receptor Tim17 PF02466.19 EJP62951.1 - 1e-26 93.5 5.4 1.5e-26 93.0 5.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LON_substr_bdg PF02190.16 EJP62953.1 - 2.2e-24 86.5 0.0 4.8e-24 85.4 0.0 1.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EJP62953.1 - 1.7e-11 43.7 10.3 3.9e-11 42.6 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP62953.1 - 9.4e-09 35.0 7.8 1.9e-08 34.0 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP62953.1 - 1.9e-08 34.2 12.3 3.3e-08 33.4 5.6 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EJP62953.1 - 5.4e-08 33.0 10.4 1.3e-07 31.8 10.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EJP62953.1 - 9.2e-08 31.8 9.8 2.1e-07 30.7 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP62953.1 - 3e-07 30.3 10.0 5.9e-07 29.3 10.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EJP62953.1 - 7.7e-07 29.2 6.6 2.9e-06 27.3 6.8 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EJP62953.1 - 1.2e-06 28.2 8.2 2.7e-06 27.1 8.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EJP62953.1 - 0.0014 18.4 7.7 0.0043 16.8 7.7 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EJP62953.1 - 0.0025 18.1 6.0 0.0063 16.8 6.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 EJP62953.1 - 0.006 16.2 7.2 0.012 15.2 7.2 1.5 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_10 PF16685.5 EJP62953.1 - 0.0074 16.4 6.8 0.015 15.4 6.8 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 DZR PF12773.7 EJP62953.1 - 0.04 14.0 1.5 0.04 14.0 1.5 1.8 2 0 0 2 2 2 0 Double zinc ribbon U-box PF04564.15 EJP62953.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 U-box domain HrpF PF06266.12 EJP62953.1 - 0.21 11.9 1.0 0.89 9.9 0.5 2.2 2 0 0 2 2 2 0 HrpF protein zf-RING_6 PF14835.6 EJP62953.1 - 0.29 11.0 4.5 0.57 10.1 4.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zinc_ribbon_15 PF17032.5 EJP62953.1 - 0.44 11.3 3.8 0.95 10.3 3.8 1.6 1 0 0 1 1 1 0 zinc-ribbon family Neisseria_TspB PF05616.13 EJP62953.1 - 1.5 7.2 6.0 2.4 6.5 6.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein zf-C3HC4_5 PF17121.5 EJP62953.1 - 2 8.4 6.4 12 5.9 5.5 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) INSIG PF07281.12 EJP62954.1 - 6.2e-77 258.0 0.5 8.1e-77 257.6 0.5 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) ABC_membrane PF00664.23 EJP62955.1 - 8.2e-80 268.4 33.6 6.5e-47 160.5 14.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP62955.1 - 5.8e-69 230.9 0.0 2.9e-33 115.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP62955.1 - 1.9e-11 43.9 2.7 0.0003 20.3 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EJP62955.1 - 1.9e-09 37.6 0.0 0.0016 18.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EJP62955.1 - 3.6e-08 33.0 1.1 0.0029 17.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EJP62955.1 - 8.4e-08 31.4 1.0 0.026 13.3 0.0 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EJP62955.1 - 2e-07 31.3 0.9 0.048 13.9 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJP62955.1 - 2.3e-05 24.8 6.8 0.0097 16.3 0.3 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 EJP62955.1 - 3.7e-05 23.6 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EJP62955.1 - 4.7e-05 22.8 0.0 0.35 10.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.6 EJP62955.1 - 0.00032 20.6 0.0 4.7 6.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EJP62955.1 - 0.00033 20.3 4.7 0.19 11.3 0.4 3.3 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 EJP62955.1 - 0.00052 19.8 2.2 2.3 7.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.6 EJP62955.1 - 0.00096 19.3 2.9 1.8 8.8 0.3 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 EJP62955.1 - 0.002 17.3 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 EJP62955.1 - 0.0083 15.6 0.1 2.5 7.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 EJP62955.1 - 0.009 15.9 0.2 4.8 7.0 0.0 3.0 3 0 0 3 3 2 1 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 EJP62955.1 - 0.012 16.1 3.6 0.62 10.5 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EJP62955.1 - 0.022 14.9 0.1 12 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EJP62955.1 - 0.023 14.7 0.2 9.8 6.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EJP62955.1 - 0.04 13.8 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 EJP62955.1 - 0.052 13.6 0.2 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EJP62955.1 - 0.08 13.0 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EJP62955.1 - 0.086 13.2 0.3 7 7.1 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_28 PF13521.6 EJP62955.1 - 0.089 13.0 0.0 3 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain FumaraseC_C PF10415.9 EJP62955.1 - 0.12 12.8 0.2 0.37 11.2 0.2 1.9 1 0 0 1 1 1 0 Fumarase C C-terminus AAA_18 PF13238.6 EJP62955.1 - 0.16 12.5 0.0 11 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2628 PF10947.8 EJP62955.1 - 3.2 8.2 9.5 0.75 10.2 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) NACHT PF05729.12 EJP62956.1 - 4.7e-06 26.6 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 EJP62956.1 - 0.00092 18.8 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 EJP62956.1 - 0.001 19.5 0.0 0.0041 17.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Hydrolase_4 PF12146.8 EJP62956.1 - 0.0031 16.8 0.2 0.11 11.7 0.0 2.8 3 0 0 3 3 3 1 Serine aminopeptidase, S33 ATPase_2 PF01637.18 EJP62956.1 - 0.0065 16.4 0.0 0.052 13.5 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea PGAP1 PF07819.13 EJP62956.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EJP62956.1 - 0.012 16.2 0.2 0.04 14.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Frtz PF11768.8 EJP62956.1 - 0.033 12.5 0.0 0.057 11.7 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz AAA PF00004.29 EJP62956.1 - 0.055 13.9 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LCAT PF02450.15 EJP62956.1 - 0.085 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase MTABC_N PF16185.5 EJP62956.1 - 0.12 11.9 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region RNA_helicase PF00910.22 EJP62956.1 - 0.17 12.3 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Fructosamin_kin PF03881.14 EJP62957.1 - 1.1e-41 142.9 0.0 1.6e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Peptidase_M3 PF01432.20 EJP62958.1 - 2.1e-96 324.0 0.1 2.9e-96 323.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 Lipase_3 PF01764.25 EJP62959.1 - 1.2e-28 99.8 0.0 2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EJP62959.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EJP62959.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EJP62959.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.21 EJP62960.1 - 5.2e-63 213.0 0.0 7.3e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family IF-2B PF01008.17 EJP62961.1 - 1.8e-47 161.9 0.0 2.1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4177 PF13783.6 EJP62961.1 - 0.019 15.3 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) SpoU_sub_bind PF08032.12 EJP62961.1 - 0.049 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Pilus_CpaD PF09476.10 EJP62961.1 - 0.1 12.3 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Methyltransf_33 PF10017.9 EJP62962.1 - 7.9e-79 265.0 0.0 1.3e-78 264.3 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EJP62962.1 - 3.8e-20 72.5 1.9 1.1e-18 67.8 1.9 2.3 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EJP62962.1 - 2.4e-07 31.3 0.2 6.1e-07 30.0 0.2 1.7 1 0 0 1 1 1 1 DinB superfamily Amidase PF01425.21 EJP62963.1 - 2.2e-97 326.9 0.0 5.4e-97 325.6 0.0 1.6 1 1 0 1 1 1 1 Amidase ABC_membrane PF00664.23 EJP62964.1 - 3.6e-48 164.6 12.2 8.3e-48 163.4 12.2 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EJP62964.1 - 2.5e-33 115.5 0.0 4.9e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter MFS_1 PF07690.16 EJP62964.1 - 5.2e-33 114.4 23.4 5.2e-33 114.4 23.4 3.8 4 0 0 4 4 4 1 Major Facilitator Superfamily SMC_N PF02463.19 EJP62964.1 - 1.1e-05 24.9 0.0 0.00018 21.0 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJP62964.1 - 0.0081 16.4 0.1 0.058 13.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EJP62964.1 - 0.0085 14.9 0.1 0.031 13.1 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 EJP62964.1 - 0.024 14.3 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EJP62964.1 - 0.22 11.8 1.2 2.2 8.6 1.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.16 EJP62965.1 - 9.4e-31 107.0 40.2 9.4e-31 107.0 40.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP62965.1 - 9.7e-07 28.0 28.3 4.1e-06 25.9 28.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EJP62965.1 - 1.5e-05 23.7 0.6 2.4e-05 23.0 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Adenylsucc_synt PF00709.21 EJP62966.1 - 1.4e-155 518.4 0.0 1.6e-155 518.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Mur_ligase PF01225.25 EJP62966.1 - 0.091 13.1 0.1 0.5 10.7 0.0 2.2 3 0 0 3 3 3 0 Mur ligase family, catalytic domain Haem_oxygenas_2 PF14518.6 EJP62966.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Iron-containing redox enzyme Dynamin_N PF00350.23 EJP62969.1 - 1.7e-36 125.8 0.1 3.3e-36 124.9 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EJP62969.1 - 7.9e-27 94.2 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EJP62969.1 - 8e-05 22.7 0.0 0.00036 20.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 EJP62969.1 - 0.0088 16.2 0.2 0.077 13.2 0.0 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain DSPc PF00782.20 EJP62970.1 - 1.1e-09 38.2 0.0 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EJP62970.1 - 0.023 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Ribonuclease_3 PF00636.26 EJP62972.1 - 2.5e-40 137.3 0.1 5.6e-19 68.7 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EJP62972.1 - 2.7e-26 92.2 0.1 1.1e-10 41.8 0.1 3.9 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EJP62972.1 - 1.3e-19 70.1 0.0 1.6e-17 63.4 0.0 3.0 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 EJP62972.1 - 2.4e-18 66.5 0.0 1.4e-17 64.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP62972.1 - 2.1e-15 57.2 0.0 5.6e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJP62972.1 - 2.5e-14 53.4 0.0 5.1e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EJP62972.1 - 0.0002 21.1 0.1 0.00036 20.3 0.1 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EJP62972.1 - 0.00044 19.5 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 EJP62972.1 - 0.00057 18.7 0.1 0.001 17.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pro_dh PF01619.18 EJP62972.1 - 0.035 13.6 0.3 0.88 9.0 0.0 2.8 4 0 0 4 4 4 0 Proline dehydrogenase MPP6 PF10175.9 EJP62973.1 - 0.039 14.4 1.4 0.059 13.9 0.1 2.0 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Tam41_Mmp37 PF09139.11 EJP62975.1 - 1.5e-124 415.7 0.0 1.7e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DNase_NucA_NucB PF14040.6 EJP62977.1 - 1.2e-19 70.8 0.6 2e-19 70.1 0.6 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Gly_transf_sug PF04488.15 EJP62979.1 - 4e-17 62.6 0.1 7.2e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EJP62979.1 - 0.0098 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EJP62979.1 - 0.06 12.6 1.0 0.2 10.9 0.1 1.9 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Pkinase PF00069.25 EJP62980.1 - 3.8e-62 210.1 1.9 3e-61 207.1 1.9 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP62980.1 - 8.3e-52 176.0 0.1 1.2e-51 175.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EJP62980.1 - 3.2e-20 72.2 0.0 1.1e-19 70.6 0.0 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 EJP62980.1 - 6.9e-10 38.7 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EJP62980.1 - 2.8e-07 29.7 0.0 4.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EJP62980.1 - 0.00046 20.2 0.1 0.0014 18.6 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EJP62980.1 - 0.0062 15.5 0.1 0.0092 15.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EJP62980.1 - 0.011 15.1 0.1 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 EJP62980.1 - 0.019 15.5 0.0 0.05 14.1 0.0 1.7 1 0 0 1 1 1 0 PH domain Seadorna_VP7 PF07387.11 EJP62980.1 - 0.073 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PH_11 PF15413.6 EJP62980.1 - 0.085 13.3 0.0 0.39 11.1 0.0 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain MFS_1 PF07690.16 EJP62981.1 - 9.5e-09 34.6 27.1 2.6e-08 33.2 27.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EJP62981.1 - 1.9e-05 24.4 2.4 1.9e-05 24.4 2.4 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF4499 PF14934.6 EJP62981.1 - 0.0058 16.9 3.2 0.038 14.3 1.8 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) Sugar_tr PF00083.24 EJP62981.1 - 0.008 15.1 12.4 0.046 12.6 12.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter ECH_1 PF00378.20 EJP62983.1 - 6.7e-43 146.8 0.0 9.6e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP62983.1 - 1e-20 74.5 0.1 1.3e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EJP62983.1 - 0.023 14.6 0.0 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 DUF872 PF05915.12 EJP62984.1 - 0.092 12.9 0.7 0.16 12.1 0.7 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) APH PF01636.23 EJP62985.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.25 EJP62988.1 - 5.2e-10 39.1 0.1 2.3e-09 37.0 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EJP62988.1 - 0.00048 20.1 0.2 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 EJP62988.1 - 0.00053 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EJP62988.1 - 0.012 15.1 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ECH_1 PF00378.20 EJP62989.1 - 1.6e-57 194.7 0.0 2.5e-57 194.1 0.0 1.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP62989.1 - 5.9e-26 91.7 0.2 1.6e-25 90.4 0.1 1.6 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EJP62989.1 - 0.016 15.2 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 UPF0444 PF15475.6 EJP62989.1 - 0.089 13.1 1.1 0.15 12.3 1.1 1.3 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 DLH PF01738.18 EJP62989.1 - 0.11 12.1 0.3 0.24 10.9 0.3 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Ribonuc_L-PSP PF01042.21 EJP62991.1 - 1.7e-17 63.5 0.0 2.2e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Complex1_LYR PF05347.15 EJP62993.1 - 9.4e-10 38.4 3.8 2.2e-08 34.0 3.8 2.1 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Herpes_gE PF02480.16 EJP62995.1 - 0.0083 14.9 1.0 0.0083 14.9 1.0 1.3 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E PSI PF01437.25 EJP62995.1 - 0.0091 16.5 10.6 0.014 15.9 10.6 1.3 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 EJP62995.1 - 0.084 12.6 11.3 0.15 11.8 11.3 1.4 1 0 0 1 1 1 0 Integrin plexin domain ThiS PF02597.20 EJP62996.1 - 3e-11 43.8 0.0 3.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 ThiS family Arginosuc_synth PF00764.19 EJP62997.1 - 1.3e-139 465.9 0.0 1.5e-139 465.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EJP62997.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Dynamitin PF04912.14 EJP62998.1 - 6e-102 341.9 17.6 1.8e-101 340.3 17.6 1.6 1 1 0 1 1 1 1 Dynamitin Fzo_mitofusin PF04799.13 EJP62998.1 - 0.00042 19.9 2.7 0.38 10.3 0.0 3.1 3 0 0 3 3 3 1 fzo-like conserved region Laminin_II PF06009.12 EJP62998.1 - 0.013 15.5 1.7 0.013 15.5 1.7 3.2 2 1 2 4 4 4 0 Laminin Domain II TPR_MLP1_2 PF07926.12 EJP62998.1 - 0.035 14.2 18.1 0.074 13.1 3.6 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Cytochrom_B562 PF07361.11 EJP62998.1 - 0.051 14.2 11.6 0.48 11.1 0.3 3.5 3 1 0 3 3 3 0 Cytochrome b562 OmpH PF03938.14 EJP62998.1 - 0.054 13.8 14.5 1.2 9.4 1.8 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) FH2 PF02181.23 EJP62998.1 - 0.058 12.5 5.3 2.3 7.2 0.0 2.9 3 0 0 3 3 3 0 Formin Homology 2 Domain XhlA PF10779.9 EJP62998.1 - 0.069 13.4 0.3 0.069 13.4 0.3 3.9 4 1 1 5 5 3 0 Haemolysin XhlA DUF2408 PF10303.9 EJP62998.1 - 0.093 13.3 5.4 0.24 12.0 0.2 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2408) DUF4423 PF14394.6 EJP62998.1 - 0.095 12.4 1.2 0.32 10.7 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4423) FapA PF03961.13 EJP62998.1 - 0.1 11.2 3.4 0.073 11.7 0.4 2.0 2 1 1 3 3 3 0 Flagellar Assembly Protein A KxDL PF10241.9 EJP62998.1 - 0.12 12.7 5.8 0.45 10.8 0.6 2.9 3 0 0 3 3 2 0 Uncharacterized conserved protein YabA PF06156.13 EJP62998.1 - 0.14 12.8 4.4 17 6.1 0.1 3.1 3 0 0 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 EJP62998.1 - 0.14 11.4 17.8 1.1 8.5 4.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EJP62998.1 - 0.14 12.3 3.4 5.7 7.1 0.1 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family FliD_N PF02465.18 EJP62998.1 - 0.16 12.7 14.4 1.4 9.6 1.3 3.8 4 0 0 4 4 3 0 Flagellar hook-associated protein 2 N-terminus DUF4140 PF13600.6 EJP62998.1 - 0.2 12.1 10.7 15 6.1 0.3 3.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3958 PF13125.6 EJP62998.1 - 0.2 11.9 5.9 9.2 6.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) Spore_III_AB PF09548.10 EJP62998.1 - 0.22 11.6 3.6 0.3 11.2 0.1 2.5 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Prefoldin_2 PF01920.20 EJP62998.1 - 0.26 11.2 8.8 0.69 9.9 0.7 3.6 4 0 0 4 4 3 0 Prefoldin subunit Snapin_Pallidin PF14712.6 EJP62998.1 - 0.27 11.7 11.8 2.3 8.7 2.6 4.3 3 2 1 4 4 4 0 Snapin/Pallidin Syntaxin_2 PF14523.6 EJP62998.1 - 0.3 11.5 5.2 26 5.3 0.3 3.3 3 0 0 3 3 3 0 Syntaxin-like protein LXG PF04740.12 EJP62998.1 - 0.3 10.8 6.8 1.3 8.7 1.0 2.9 3 0 0 3 3 3 0 LXG domain of WXG superfamily GAS PF13851.6 EJP62998.1 - 0.48 9.7 11.2 0.23 10.8 1.0 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding V-SNARE_C PF12352.8 EJP62998.1 - 0.5 10.7 5.4 11 6.4 0.1 3.3 4 0 0 4 4 2 0 Snare region anchored in the vesicle membrane C-terminus GrpE PF01025.19 EJP62998.1 - 0.67 9.6 11.2 3.9 7.1 0.2 3.5 2 1 1 3 3 3 0 GrpE Baculo_PEP_C PF04513.12 EJP62998.1 - 0.68 10.0 9.0 2.3 8.3 0.5 3.1 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc24 PF08286.11 EJP62998.1 - 0.73 10.1 14.0 0.27 11.5 1.2 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 SKA1 PF07160.12 EJP62998.1 - 0.99 9.2 4.5 2.6 7.8 0.4 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DHR10 PF18595.1 EJP62998.1 - 1.1 9.4 24.2 2.9 8.0 6.5 3.8 2 2 2 4 4 3 0 Designed helical repeat protein 10 domain Jnk-SapK_ap_N PF09744.9 EJP62998.1 - 1.1 9.5 8.4 1.5 9.0 0.5 3.2 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 EJP62998.1 - 1.1 8.6 10.7 0.55 9.7 1.0 3.1 3 0 0 3 3 3 0 Golgin subfamily A member 5 MRPL52 PF18699.1 EJP62998.1 - 1.2 9.3 0.0 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Mitoribosomal protein mL52 Noelin-1 PF12308.8 EJP62998.1 - 2.2 8.3 8.1 7 6.7 1.1 2.8 3 0 0 3 3 2 0 Neurogenesis glycoprotein DivIC PF04977.15 EJP62998.1 - 2.6 7.9 22.3 0.25 11.1 1.9 4.0 4 0 0 4 4 4 0 Septum formation initiator Atg14 PF10186.9 EJP62998.1 - 2.7 7.0 7.5 8.4 5.4 0.2 2.8 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EJP62998.1 - 2.8 6.7 17.7 2.1 7.1 2.8 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein YkyA PF10368.9 EJP62998.1 - 2.9 7.5 11.0 0.76 9.4 0.8 2.9 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein zf-C4H2 PF10146.9 EJP62998.1 - 3.4 7.9 8.6 9.7 6.4 1.2 2.9 2 1 1 3 3 3 0 Zinc finger-containing protein TMPIT PF07851.13 EJP62998.1 - 3.6 6.8 7.2 1.7 7.8 0.5 2.6 3 0 0 3 3 3 0 TMPIT-like protein COG2 PF06148.11 EJP62998.1 - 4.1 7.5 5.7 25 4.9 0.2 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Fmp27_WPPW PF10359.9 EJP62998.1 - 4.3 6.1 7.5 9 5.0 0.4 3.0 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain Prominin PF05478.11 EJP62998.1 - 4.5 5.1 4.3 5.6 4.8 0.5 2.1 1 1 1 2 2 2 0 Prominin SOGA PF11365.8 EJP62998.1 - 4.9 8.3 7.3 2.1 9.5 0.5 3.1 3 0 0 3 3 3 0 Protein SOGA DUF2203 PF09969.9 EJP62998.1 - 5.4 7.8 14.4 2.3 9.0 0.7 3.5 2 2 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) Phage_GP20 PF06810.11 EJP62998.1 - 5.5 6.8 15.3 0.33 10.7 0.4 3.4 3 0 0 3 3 3 0 Phage minor structural protein GP20 APG6_N PF17675.1 EJP62998.1 - 5.8 7.5 22.0 28 5.2 1.4 3.2 2 1 0 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 EJP62998.1 - 6.4 7.3 13.6 4.8 7.7 0.1 3.4 3 0 0 3 3 3 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 EJP62998.1 - 6.5 6.2 11.4 6.5 6.2 6.9 2.5 1 1 1 2 2 2 0 Exonuclease VII, large subunit Muted PF14942.6 EJP62998.1 - 6.7 7.0 11.7 1.8 8.9 0.8 2.9 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein DUF16 PF01519.16 EJP62998.1 - 7.8 7.1 7.7 3.7e+02 1.7 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 RTC4 PF14474.6 EJP62999.1 - 1.7e-30 105.7 0.0 3e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Sec10 PF07393.11 EJP63000.1 - 5.1e-218 726.0 5.3 6.1e-218 725.7 5.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MA3 PF02847.17 EJP63000.1 - 0.055 13.4 0.5 16 5.5 0.0 3.5 3 0 0 3 3 3 0 MA3 domain Ku_PK_bind PF08785.11 EJP63000.1 - 0.061 13.5 0.1 0.44 10.7 0.0 2.6 2 0 0 2 2 2 0 Ku C terminal domain like Methyltransf_23 PF13489.6 EJP63000.1 - 0.066 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HORMA PF02301.18 EJP63000.1 - 0.082 12.5 0.6 0.22 11.1 0.1 2.0 2 1 0 2 2 2 0 HORMA domain PWI PF01480.17 EJP63000.1 - 0.087 13.2 0.9 3 8.2 0.4 3.5 2 1 0 2 2 2 0 PWI domain MRP-S31 PF15433.6 EJP63000.1 - 0.25 11.0 1.8 18 4.9 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Baculo_PEP_C PF04513.12 EJP63000.1 - 3 7.9 6.6 14 5.7 0.9 3.7 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prenyltransf PF01255.19 EJP63001.1 - 2.2e-05 24.1 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase 2OG-FeII_Oxy_2 PF13532.6 EJP63002.1 - 1.3e-28 100.5 0.0 1.9e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Met_10 PF02475.16 EJP63003.1 - 4.6e-73 245.2 0.0 5.8e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein DUF1752 PF08550.10 EJP63004.1 - 3.4e-11 42.8 5.0 7e-11 41.8 5.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RNB PF00773.19 EJP63005.1 - 7.2e-45 153.7 0.0 1.9e-44 152.4 0.0 1.6 1 1 0 1 1 1 1 RNB domain DEC-1_N PF04625.13 EJP63006.1 - 0.42 9.6 15.1 1.2 8.0 13.8 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region PRCC PF10253.9 EJP63006.1 - 8.6 7.1 8.3 0.28 11.9 1.6 1.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2415 PF10313.9 EJP63007.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) tRNA-synt_2b PF00587.25 EJP63008.1 - 3.4e-34 118.4 0.0 7.4e-33 114.0 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EJP63008.1 - 7.9e-18 64.4 0.3 7.9e-18 64.4 0.3 1.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 EJP63008.1 - 6.4e-14 51.8 0.0 1.4e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EJP63008.1 - 3.9e-12 46.0 0.0 1e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 TGS domain zf-HIT PF04438.16 EJP63009.1 - 1.5e-09 37.6 5.0 1.5e-09 37.6 5.0 1.7 2 0 0 2 2 2 1 HIT zinc finger Thioredoxin PF00085.20 EJP63011.1 - 7.8e-62 205.7 7.4 6.3e-31 106.4 0.1 4.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EJP63011.1 - 1e-48 165.7 2.2 5.8e-37 127.4 0.3 3.5 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EJP63011.1 - 4.9e-09 36.6 1.5 0.0028 18.1 0.0 3.6 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EJP63011.1 - 5.4e-09 35.8 0.4 0.016 14.6 0.0 3.5 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EJP63011.1 - 2.2e-08 34.3 0.1 0.029 14.7 0.0 4.0 3 2 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 EJP63011.1 - 1.8e-07 31.1 3.2 0.0081 16.1 0.1 3.2 4 0 0 4 4 4 2 AhpC/TSA family Calsequestrin PF01216.17 EJP63011.1 - 3.1e-07 29.8 1.7 6.5e-07 28.7 1.7 1.6 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.6 EJP63011.1 - 3.6e-07 30.3 0.1 0.02 15.1 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 EJP63011.1 - 8.4e-05 22.3 4.1 0.47 10.2 0.0 3.6 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.6 EJP63011.1 - 0.082 13.1 3.9 35 4.5 0.4 3.8 2 2 1 3 3 3 0 Thioredoxin Glutaredoxin PF00462.24 EJP63011.1 - 0.12 12.6 1.3 25 5.2 0.0 3.3 2 1 0 2 2 2 0 Glutaredoxin Oxidored_FMN PF00724.20 EJP63012.1 - 1.5e-61 208.6 0.0 1.8e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3070 PF11270.8 EJP63012.1 - 0.6 10.4 2.7 2.1 8.6 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) peroxidase PF00141.23 EJP63013.1 - 1.5e-47 162.2 0.0 3.2e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Suf PF05843.14 EJP63014.1 - 1.8e-05 24.9 1.4 1.6 8.6 0.0 3.5 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EJP63014.1 - 0.42 11.6 5.9 1.6e+02 3.5 0.0 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat Syja_N PF02383.18 EJP63015.1 - 7.9e-76 255.4 0.1 1.6e-75 254.4 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 EJP63015.1 - 2.6e-09 37.0 0.1 4.6e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 14-3-3 PF00244.20 EJP63017.1 - 2.8e-107 357.3 1.0 3.3e-107 357.0 1.0 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 EJP63017.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF Lipase_3 PF01764.25 EJP63018.1 - 6.7e-30 103.8 0.0 9.2e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EJP63018.1 - 9.2e-06 26.4 0.0 1.3e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EJP63018.1 - 5.9e-05 23.3 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EJP63018.1 - 0.00068 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP63018.1 - 0.0015 18.2 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 EJP63018.1 - 0.0033 17.0 0.0 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 EJP63018.1 - 0.048 13.4 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 EJP63018.1 - 0.053 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_8 PF06259.12 EJP63018.1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 EJP63018.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase PF00151.19 EJP63018.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipase DUF726 PF05277.12 EJP63018.1 - 0.2 10.5 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) AltA1 PF16541.5 EJP63019.1 - 0.0029 18.5 0.3 0.0038 18.1 0.3 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 T5orf172 PF10544.9 EJP63020.1 - 1.4e-16 60.9 0.0 3.3e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EJP63020.1 - 7.2e-13 49.0 0.1 1.7e-12 47.8 0.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 SRX PF09201.10 EJP63020.1 - 0.051 13.4 0.1 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit APH PF01636.23 EJP63021.1 - 5.3e-19 69.1 0.8 6.9e-19 68.7 0.8 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP63021.1 - 0.038 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L36e PF01158.18 EJP63022.1 - 4.4e-42 142.2 6.0 5e-42 142.1 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 EJP63022.1 - 0.0091 16.1 1.2 0.011 15.9 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PBS_linker_poly PF00427.21 EJP63022.1 - 0.12 12.4 0.2 0.14 12.2 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide TUG-UBL1 PF11470.8 EJP63023.1 - 1.3e-24 86.1 0.0 3e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 EJP63023.1 - 0.029 14.4 0.2 0.082 13.0 0.1 1.8 2 0 0 2 2 2 0 Raf-like Ras-binding domain DUF4294 PF14127.6 EJP63023.1 - 0.032 14.2 0.1 0.079 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) Proteasome PF00227.26 EJP63024.1 - 1.4e-36 125.8 0.0 1.5e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.20 EJP63025.1 - 1.5e-48 164.7 1.6 1.5e-48 164.7 1.6 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EJP63025.1 - 5.4e-46 156.6 7.2 5.4e-46 156.6 7.2 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EJP63025.1 - 9e-23 81.7 1.8 1.1e-21 78.1 1.8 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJP63025.1 - 2.3e-19 69.3 0.0 4.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EJP63025.1 - 2.5e-19 68.7 0.0 6.5e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP63025.1 - 1.7e-07 31.2 1.0 1.1e-06 28.6 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP63025.1 - 2.5e-05 24.7 0.0 8.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RhoGEF PF00621.20 EJP63026.1 - 1.1e-07 32.3 0.0 1.6e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Cas_Cas7 PF05107.12 EJP63027.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 SBDS PF01172.18 EJP63028.1 - 1.3e-24 86.1 0.3 1.5e-24 85.9 0.3 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein OPA3 PF07047.12 EJP63030.1 - 1.6e-44 150.6 5.6 1.6e-44 150.6 5.6 1.9 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) DUF2052 PF09747.9 EJP63030.1 - 0.00056 20.1 2.8 0.00056 20.1 2.8 1.9 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Dicty_REP PF05086.12 EJP63030.1 - 0.0098 13.9 6.5 0.011 13.8 6.5 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein PV-1 PF06637.11 EJP63030.1 - 0.67 8.7 6.5 0.082 11.7 0.8 1.9 2 0 0 2 2 2 0 PV-1 protein (PLVAP) FSA_C PF10479.9 EJP63030.1 - 0.86 7.7 5.5 1.1 7.3 5.5 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Menin PF05053.13 EJP63030.1 - 1.2 7.4 7.0 0.22 9.9 2.7 1.8 2 0 0 2 2 2 0 Menin CPSF100_C PF13299.6 EJP63030.1 - 2.3 8.4 9.1 0.75 10.0 4.4 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 EJP63030.1 - 2.3 7.1 9.2 3.7 6.5 7.7 1.6 1 1 1 2 2 2 0 Solute carrier family 12 Peptidase_S49_N PF08496.10 EJP63030.1 - 2.5 8.2 10.9 22 5.1 0.0 2.6 2 1 0 2 2 2 0 Peptidase family S49 N-terminal SSP160 PF06933.11 EJP63030.1 - 2.6 6.1 15.3 3.5 5.7 15.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sec3_C PF09763.9 EJP63030.1 - 2.9 6.2 9.0 0.36 9.2 3.4 1.8 2 0 0 2 2 2 0 Exocyst complex component Sec3 HAUS6_N PF14661.6 EJP63030.1 - 3.4 7.2 9.4 0.52 9.9 3.4 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Med3 PF11593.8 EJP63030.1 - 3.7 6.6 12.9 5.6 6.1 12.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAF-1_p150 PF11600.8 EJP63030.1 - 5.6 6.6 23.3 0.85 9.3 8.6 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAM176 PF14851.6 EJP63030.1 - 7.1 6.3 11.0 0.11 12.2 0.9 2.4 2 1 0 2 2 2 0 FAM176 family Pkinase PF00069.25 EJP63031.1 - 9.7e-69 231.7 0.0 1.3e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP63031.1 - 7.5e-41 140.1 0.0 1.1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EJP63031.1 - 1.4e-06 28.4 0.0 0.00032 20.8 0.0 2.9 2 0 0 2 2 2 1 POLO box duplicated region Kinase-like PF14531.6 EJP63031.1 - 1.7e-05 24.3 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJP63031.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Miff PF05644.11 EJP63031.1 - 0.013 15.2 7.2 0.025 14.2 7.2 1.4 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff SPX PF03105.19 EJP63031.1 - 0.016 15.2 4.2 0.033 14.1 4.2 1.4 1 0 0 1 1 1 0 SPX domain Pkinase_fungal PF17667.1 EJP63031.1 - 0.026 13.3 0.2 0.026 13.3 0.2 1.7 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 EJP63031.1 - 0.096 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Chitin_synth_2 PF03142.15 EJP63032.1 - 4.9e-284 942.8 0.0 6.4e-284 942.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EJP63032.1 - 9.5e-14 51.8 4.0 3.7e-13 49.8 4.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EJP63032.1 - 1.9e-09 37.7 0.0 2.8e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EJP63032.1 - 0.00036 20.1 0.0 0.0027 17.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EJP63032.1 - 0.011 15.6 0.0 0.097 12.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 NepR PF18557.1 EJP63032.1 - 0.22 11.2 0.1 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma factor NepR Sel1 PF08238.12 EJP63033.1 - 3.2e-42 142.0 29.7 1.6e-06 28.6 0.2 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EJP63033.1 - 0.014 16.0 4.6 4 8.3 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP63033.1 - 0.092 13.0 0.7 0.74 10.1 0.2 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Myb_DNA-bind_6 PF13921.6 EJP63034.1 - 0.00023 21.3 0.1 0.00048 20.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EJP63034.1 - 0.1 12.8 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF5542 PF17696.1 EJP63034.1 - 0.35 11.0 1.6 0.9 9.7 1.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5542) APH PF01636.23 EJP63036.1 - 1.4e-13 51.3 0.0 4.7e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP63036.1 - 0.00075 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EJP63036.1 - 0.2 11.3 0.0 0.81 9.3 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.17 EJP63036.1 - 0.2 10.9 0.0 0.34 10.2 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase SNF2_N PF00176.23 EJP63037.1 - 1.4e-50 172.0 0.0 2.2e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP63037.1 - 8.2e-15 55.1 0.1 2.3e-14 53.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UBA PF00627.31 EJP63037.1 - 9.9e-07 28.6 0.8 1.4e-05 24.9 0.1 2.5 2 0 0 2 2 2 1 UBA/TS-N domain ERCC3_RAD25_C PF16203.5 EJP63037.1 - 9.4e-05 21.7 0.2 0.00027 20.2 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase TT_ORF2 PF02957.15 EJP63037.1 - 0.0045 17.9 0.3 0.011 16.7 0.3 1.6 1 0 0 1 1 1 1 TT viral ORF2 HBS1_N PF08938.10 EJP63037.1 - 0.012 15.9 5.7 0.022 15.1 0.1 2.5 2 0 0 2 2 2 0 HBS1 N-terminus DUF515 PF04415.12 EJP63037.1 - 0.022 13.2 0.0 0.037 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) UBA_4 PF14555.6 EJP63037.1 - 0.023 14.5 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.16 EJP63037.1 - 0.028 14.1 0.5 0.082 12.6 0.1 2.0 2 0 0 2 2 2 0 CUE domain DUF2267 PF10025.9 EJP63037.1 - 0.044 14.1 0.1 0.54 10.6 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) HIGH_NTase1_ass PF16581.5 EJP63037.1 - 0.13 12.3 0.3 0.41 10.6 0.1 1.9 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region VMA21 PF09446.10 EJP63038.1 - 1.1e-15 57.4 7.8 1.6e-15 56.9 7.8 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.9 EJP63039.1 - 1.3e-27 96.3 0.5 4.5e-27 94.5 0.5 2.0 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) LMWPc PF01451.21 EJP63039.1 - 0.011 16.1 0.1 0.019 15.4 0.1 1.3 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase CorA PF01544.18 EJP63040.1 - 0.0009 18.6 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribosomal_L35Ae PF01247.18 EJP63041.1 - 4.3e-40 135.8 0.1 4.9e-40 135.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EJP63041.1 - 9.4e-05 22.6 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 EJP63041.1 - 0.35 10.6 2.0 3 7.7 0.2 2.9 3 1 0 3 3 3 0 Putative transposon-encoded protein (DUF2080) G6PD_C PF02781.16 EJP63042.1 - 5e-115 383.7 0.0 9.3e-115 382.8 0.0 1.4 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EJP63042.1 - 3.4e-61 206.9 0.0 6.2e-61 206.1 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Med14 PF08638.11 EJP63043.1 - 5.3e-65 218.4 0.1 1.1e-64 217.4 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Amino_oxidase PF01593.24 EJP63044.1 - 3.9e-18 66.0 0.0 6.2e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP63044.1 - 4.4e-13 49.3 0.0 1.2e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP63044.1 - 7.7e-09 35.6 0.1 2.4e-06 27.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EJP63044.1 - 0.0018 18.3 0.1 0.0064 16.5 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EJP63044.1 - 0.0066 15.3 0.0 0.0095 14.8 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 EJP63044.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EJP63044.1 - 0.021 14.0 0.0 0.045 13.0 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP63044.1 - 0.13 11.5 0.3 0.22 10.7 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain zf-CCCH_2 PF14608.6 EJP63045.1 - 5.9e-14 51.9 58.5 0.00015 22.1 12.2 5.6 5 1 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EJP63045.1 - 0.025 14.9 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) FAD_binding_4 PF01565.23 EJP63046.1 - 3.4e-20 72.2 1.3 6.5e-20 71.3 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain Aminotran_1_2 PF00155.21 EJP63047.1 - 1.7e-18 66.9 0.0 2.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EJP63047.1 - 2.2e-09 36.6 0.0 3.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Sugar_tr PF00083.24 EJP63049.1 - 4.1e-68 230.3 25.1 4.9e-68 230.1 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP63049.1 - 1.7e-22 79.8 39.7 1.8e-20 73.2 31.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 EJP63049.1 - 0.17 11.8 2.8 0.45 10.4 2.8 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain AnmK PF03702.14 EJP63050.1 - 3.9e-87 292.7 0.0 4.5e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase RIC1 PF07064.13 EJP63051.1 - 1e-88 297.0 0.0 1.4e-88 296.6 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 EJP63051.1 - 0.0015 18.8 0.0 0.5 10.7 0.0 4.5 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJP63051.1 - 0.054 14.4 1.0 15 6.6 0.1 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat CTP_transf_like PF01467.26 EJP63052.1 - 9.9e-19 67.9 0.0 1.5e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like CK_II_beta PF01214.18 EJP63053.1 - 1.9e-75 252.7 0.1 2.4e-75 252.3 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PAP2 PF01569.21 EJP63054.1 - 1.4e-22 80.0 1.4 4.7e-22 78.2 1.4 1.9 1 1 0 1 1 1 1 PAP2 superfamily Ribosomal_L2_C PF03947.18 EJP63055.1 - 1.3e-52 177.3 2.6 5.8e-52 175.2 3.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EJP63055.1 - 2.2e-23 82.0 1.0 4.2e-23 81.1 1.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 EJP63056.1 - 7.1e-44 148.6 0.1 1.7e-43 147.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EJP63056.1 - 6.4e-35 119.8 0.1 1.1e-34 119.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_M16_C PF05193.21 EJP63056.1 - 0.27 11.2 1.3 5.7 6.9 0.0 2.6 3 0 0 3 3 3 0 Peptidase M16 inactive domain WD40 PF00400.32 EJP63057.1 - 2.7e-19 69.2 5.1 0.00038 21.2 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP63057.1 - 1.6e-11 44.4 0.1 0.24 11.7 0.0 5.1 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 EJP63057.1 - 0.0051 15.9 0.0 0.58 9.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) eIF2A PF08662.11 EJP63057.1 - 0.046 13.6 0.8 4.5 7.1 0.0 2.9 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EJP63057.1 - 0.058 12.0 0.1 0.32 9.6 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ras PF00071.22 EJP63057.1 - 0.092 12.3 0.0 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 Ras family Gly_transf_sug PF04488.15 EJP63058.1 - 1.8e-08 34.9 0.0 4.2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EJP63058.1 - 0.036 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Fungal_trans PF04082.18 EJP63059.1 - 5.3e-20 71.6 0.0 1.1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63059.1 - 6.5e-09 35.8 9.5 6.5e-09 35.8 9.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.6 EJP63060.1 - 4e-14 52.8 0.0 8.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP63060.1 - 9.5e-11 41.9 0.0 2.3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP63060.1 - 3.6e-06 26.9 0.4 1.1e-05 25.3 0.4 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EJP63060.1 - 4.9e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EJP63060.1 - 0.00033 20.8 0.0 0.00062 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 EJP63060.1 - 0.0004 20.9 0.0 0.00091 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF5053 PF16476.5 EJP63060.1 - 0.02 14.5 0.0 0.059 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) GST_C_3 PF14497.6 EJP63060.1 - 0.059 13.6 0.0 0.32 11.2 0.0 2.2 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.24 EJP63061.1 - 3.2e-29 102.1 32.3 3e-18 65.9 6.9 2.4 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EJP63061.1 - 1.6e-21 76.6 20.6 1e-15 57.6 9.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1774 PF08611.10 EJP63061.1 - 0.74 10.2 5.3 0.13 12.6 0.8 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Trep_Strep PF09605.10 EJP63061.1 - 1.1 9.2 14.7 0.17 11.8 4.1 2.8 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) zf-C2H2 PF00096.26 EJP63063.1 - 0.00021 21.5 12.9 0.0066 16.8 2.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP63063.1 - 0.033 14.6 2.3 0.033 14.6 2.3 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Integrin_B_tail PF07965.12 EJP63063.1 - 0.037 14.5 0.9 0.079 13.5 0.2 1.8 1 1 1 2 2 2 0 Integrin beta tail domain zf-C2H2_4 PF13894.6 EJP63063.1 - 0.051 14.4 10.6 0.22 12.5 1.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EJP63063.1 - 0.14 12.6 7.7 0.44 11.0 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Nop PF01798.18 EJP63064.1 - 9.5e-72 241.2 0.1 1.8e-71 240.2 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EJP63064.1 - 4.3e-46 156.7 2.9 5.4e-46 156.4 0.8 2.3 2 1 0 2 2 2 1 Prp31 C terminal domain TPR_19 PF14559.6 EJP63065.1 - 1e-24 86.8 1.2 8.4e-06 26.2 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat HAT PF02184.16 EJP63065.1 - 1.5e-24 85.7 65.2 7.1e-12 45.1 0.9 12.3 14 0 0 14 14 13 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EJP63065.1 - 2e-22 78.0 35.2 0.00024 21.7 0.2 10.6 6 3 5 11 11 10 7 Tetratricopeptide repeat Suf PF05843.14 EJP63065.1 - 1.3e-19 71.3 11.5 8.8e-05 22.6 0.3 6.6 2 1 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EJP63065.1 - 7.8e-09 35.3 4.6 0.2 12.1 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EJP63065.1 - 2e-08 33.8 14.0 0.11 11.7 0.6 5.5 3 2 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 EJP63065.1 - 9.4e-08 32.6 17.5 0.03 15.0 0.1 7.1 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EJP63065.1 - 2e-07 31.2 19.3 0.34 11.6 0.4 8.3 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJP63065.1 - 5.5e-07 29.2 23.1 0.29 11.4 0.0 8.7 11 0 0 11 11 9 3 Tetratricopeptide repeat NRDE-2 PF08424.10 EJP63065.1 - 1.4e-06 27.7 17.3 0.22 10.6 0.1 6.4 4 2 2 6 6 6 3 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 EJP63065.1 - 2.6e-05 24.1 9.0 2.3 8.7 0.0 7.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP63065.1 - 0.00028 21.1 17.4 7.9 6.9 0.0 6.6 6 1 2 8 8 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EJP63065.1 - 0.00086 19.3 7.4 18 5.5 0.4 5.7 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.11 EJP63065.1 - 0.0036 17.3 15.1 1 9.4 0.1 6.0 5 1 1 6 6 6 2 U3 small nucleolar RNA-associated protein 6 CheR_N PF03705.15 EJP63065.1 - 0.0038 16.9 0.1 0.013 15.2 0.1 2.0 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain TPR_1 PF00515.28 EJP63065.1 - 0.068 13.0 8.0 11 6.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EJP63065.1 - 0.45 10.7 15.5 1.2 9.3 0.2 6.1 8 0 0 8 8 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EJP63065.1 - 0.8 9.7 21.5 3.1 7.8 0.1 6.4 5 3 2 7 7 7 0 Mad3/BUB1 homology region 1 ETRAMP PF09716.10 EJP63066.1 - 1.2 9.3 3.9 12 6.0 0.2 3.7 3 1 1 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF4863 PF16155.5 EJP63068.1 - 9.2e-68 226.9 0.0 1.1e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) PAN_4 PF14295.6 EJP63069.1 - 5.2e-08 32.7 4.0 1.9e-06 27.7 0.2 3.4 4 0 0 4 4 4 2 PAN domain PAN_2 PF08276.11 EJP63069.1 - 2.7e-06 27.4 5.1 0.021 14.9 0.2 3.0 2 0 0 2 2 2 2 PAN-like domain PAN_1 PF00024.26 EJP63069.1 - 0.00014 21.8 1.2 0.0039 17.1 0.1 3.9 3 1 0 3 3 3 2 PAN domain MANEC PF07502.14 EJP63069.1 - 0.0027 17.9 2.7 0.18 12.1 0.1 3.0 2 1 0 2 2 2 2 MANEC domain Paramyxo_ncap PF00973.19 EJP63069.1 - 0.85 8.5 5.3 1.2 7.9 5.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein La PF05383.17 EJP63070.1 - 3.1e-19 68.8 0.1 5.8e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 La domain Got1 PF04178.12 EJP63071.1 - 5.5e-32 110.5 9.5 7e-32 110.2 9.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family ExoD PF06055.12 EJP63071.1 - 0.031 13.7 3.3 0.045 13.1 3.3 1.3 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD HLH PF00010.26 EJP63072.1 - 3.9e-12 45.9 0.0 1.9e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain NPR3 PF03666.13 EJP63073.1 - 4.2e-142 474.2 0.0 6.6e-142 473.6 0.0 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Ribosomal_60s PF00428.19 EJP63073.1 - 0.022 15.3 7.4 0.022 15.3 7.4 2.9 2 1 0 2 2 2 0 60s Acidic ribosomal protein Rootletin PF15035.6 EJP63073.1 - 0.11 12.5 6.9 0.048 13.7 4.0 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ATP-synt_C PF00137.21 EJP63075.1 - 1.3e-27 95.9 36.5 3.3e-17 62.6 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C FPN1 PF06963.12 EJP63075.1 - 1.5 7.3 7.1 2.2 6.7 0.1 2.5 2 1 1 3 3 3 0 Ferroportin1 (FPN1) CNH PF00780.22 EJP63076.1 - 2.7e-78 263.4 0.0 1.6e-77 260.9 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EJP63076.1 - 1.8e-42 144.6 0.0 4e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EJP63076.1 - 1.3e-34 120.0 0.0 2.2e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EJP63076.1 - 7.7e-16 57.9 0.1 1.4e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pal1 PF08316.11 EJP63077.1 - 1.4e-36 126.3 7.7 5e-34 118.0 4.5 3.4 2 1 0 2 2 2 2 Pal1 cell morphology protein polyprenyl_synt PF00348.17 EJP63078.1 - 8.1e-37 126.7 0.0 1.1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HSP20 PF00011.21 EJP63081.1 - 1.8e-11 44.1 0.0 3.3e-10 40.0 0.0 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EJP63081.1 - 0.0033 17.0 0.0 0.046 13.3 0.0 2.3 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Chorion_2 PF03964.15 EJP63081.1 - 6.2 7.7 14.2 1.3 9.9 5.9 2.5 2 0 0 2 2 2 0 Chorion family 2 MCM PF00493.23 EJP63082.1 - 3.9e-99 330.3 0.0 6e-99 329.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJP63082.1 - 1.3e-38 131.7 1.4 2.2e-38 130.9 1.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EJP63082.1 - 1.3e-28 99.3 2.9 3e-28 98.1 2.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EJP63082.1 - 3.7e-19 69.2 0.1 1.5e-18 67.3 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 EJP63082.1 - 1.3e-05 25.3 0.1 0.00028 20.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EJP63082.1 - 6.2e-05 22.5 0.0 0.00068 19.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EJP63082.1 - 0.0013 18.6 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) GGA_N-GAT PF18308.1 EJP63082.1 - 0.012 15.2 1.4 0.014 15.0 0.0 1.8 2 0 0 2 2 2 0 GGA N-GAT domain Clat_adaptor_s PF01217.20 EJP63083.1 - 1.3e-16 60.8 0.1 4.8e-16 59.0 0.1 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain NLPC_P60 PF00877.19 EJP63083.1 - 0.17 11.9 0.1 0.21 11.6 0.1 1.3 1 1 0 1 1 1 0 NlpC/P60 family COG4 PF08318.12 EJP63084.1 - 2.7e-120 401.5 0.0 4e-120 400.9 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein Sua5_yciO_yrdC PF01300.18 EJP63084.1 - 1.2e-53 181.3 0.0 3.6e-53 179.7 0.0 1.9 1 0 0 1 1 1 1 Telomere recombination Cation_ATPase_C PF00689.21 EJP63084.1 - 1e-45 155.7 0.7 1.9e-45 154.8 0.7 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EJP63084.1 - 1.4e-45 155.0 1.5 3.6e-45 153.7 1.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase SUA5 PF03481.13 EJP63084.1 - 3.9e-31 108.4 0.0 1.1e-30 106.9 0.0 1.9 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Hydrolase PF00702.26 EJP63084.1 - 7e-22 78.8 0.1 1.4e-20 74.5 0.0 3.3 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EJP63084.1 - 1.6e-16 59.8 0.0 4.2e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EJP63084.1 - 7.3e-12 45.2 0.0 2.2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EJP63084.1 - 0.00081 19.2 1.2 0.0011 18.7 0.3 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mob1_phocein PF03637.17 EJP63085.1 - 2e-40 138.6 0.1 2.8e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family bZIP_Maf PF03131.17 EJP63086.1 - 2.3e-07 31.2 10.5 7.9e-07 29.5 10.5 1.9 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 EJP63086.1 - 1.4e-06 28.3 12.5 1.4e-06 28.3 12.5 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EJP63086.1 - 2.8e-05 24.1 7.5 2.8e-05 24.1 7.5 2.4 2 0 0 2 2 2 1 Basic region leucine zipper Exonuc_VII_L PF02601.15 EJP63086.1 - 0.21 11.1 3.6 0.45 10.0 3.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 EJP63086.1 - 1.4 9.0 15.4 2.7 8.0 15.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sel1 PF08238.12 EJP63087.1 - 3.5e-16 59.3 2.1 1.6e-06 28.6 0.0 3.5 3 0 0 3 3 3 3 Sel1 repeat zf-CCCH PF00642.24 EJP63088.1 - 6.8e-11 41.8 23.0 0.00014 21.7 0.6 4.8 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EJP63088.1 - 6.3e-07 29.1 14.3 0.0023 17.7 0.2 3.9 3 1 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EJP63088.1 - 8.1e-05 22.5 8.7 0.0035 17.3 0.9 5.4 5 0 0 5 5 5 2 Zinc finger domain Torus PF16131.5 EJP63088.1 - 0.00089 19.9 28.2 0.09 13.5 1.0 5.2 2 1 3 5 5 5 3 Torus domain zf-CCCH_3 PF15663.5 EJP63088.1 - 0.016 15.4 6.5 0.016 15.4 6.5 3.3 2 1 1 3 3 3 0 Zinc-finger containing family RdgC PF04381.12 EJP63088.1 - 0.058 12.7 0.3 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC DUF737 PF05300.11 EJP63088.1 - 0.078 13.3 3.8 0.16 12.3 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) zf-C3H1 PF10650.9 EJP63088.1 - 0.25 11.1 0.1 0.25 11.1 0.1 3.3 3 0 0 3 3 3 0 Putative zinc-finger domain THOC7 PF05615.13 EJP63089.1 - 4.3e-45 153.2 12.6 4.3e-45 153.2 12.6 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 FUSC PF04632.12 EJP63089.1 - 0.00037 19.2 10.0 0.00049 18.8 10.0 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family NYD-SP28_assoc PF14775.6 EJP63089.1 - 0.38 10.9 3.9 1 9.5 0.1 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain OmpH PF03938.14 EJP63089.1 - 1.2 9.5 7.0 3 8.2 7.0 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TBCA PF02970.16 EJP63090.1 - 2.7e-25 88.5 4.1 2.7e-25 88.5 4.1 1.5 1 1 1 2 2 2 1 Tubulin binding cofactor A Spectrin PF00435.21 EJP63090.1 - 0.046 14.2 4.1 0.039 14.4 2.7 1.6 1 1 1 2 2 2 0 Spectrin repeat DUF2408 PF10303.9 EJP63090.1 - 0.12 12.9 1.0 0.14 12.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Rad21_Rec8_N PF04825.13 EJP63091.1 - 3.1e-38 130.3 0.1 5.8e-38 129.4 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EJP63091.1 - 2.7e-09 36.2 0.0 6.1e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Leo1 PF04004.13 EJP63092.1 - 1.5e-34 119.2 1.7 6.8e-34 117.1 0.0 2.3 2 0 0 2 2 2 1 Leo1-like protein DUF3336 PF11815.8 EJP63093.1 - 1.6e-35 121.8 0.2 1.1e-34 119.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EJP63093.1 - 7.4e-11 42.6 2.1 2.3e-10 41.0 2.1 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Glyco_hydro_18 PF00704.28 EJP63094.1 - 8.1e-50 170.3 0.0 1.4e-49 169.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Syntaxin PF00804.25 EJP63095.1 - 4.6e-21 75.4 14.6 4.6e-21 75.4 14.6 2.4 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 EJP63095.1 - 2.2e-12 46.8 2.7 2.2e-12 46.8 2.7 3.1 3 1 0 3 3 3 1 SNARE domain Orf78 PF06024.12 EJP63095.1 - 0.00044 20.5 0.3 0.00044 20.5 0.3 2.1 2 1 0 2 2 2 1 Orf78 (ac78) Mid2 PF04478.12 EJP63095.1 - 0.00095 19.0 0.3 0.0018 18.1 0.3 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Use1 PF09753.9 EJP63095.1 - 0.0016 18.2 11.7 0.0038 17.0 11.3 1.7 1 1 1 2 2 2 1 Membrane fusion protein Use1 Syntaxin_2 PF14523.6 EJP63095.1 - 0.0041 17.4 4.2 0.0041 17.4 4.2 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Mod_r PF07200.13 EJP63095.1 - 0.0084 16.2 15.0 0.22 11.6 5.3 2.8 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein ODV-E18 PF10717.9 EJP63095.1 - 0.0089 15.9 0.7 0.031 14.1 0.1 2.0 2 0 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 Sigma_reg_N PF13800.6 EJP63095.1 - 0.012 15.9 0.2 0.026 14.8 0.2 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal NB PF04159.13 EJP63095.1 - 0.015 15.3 0.5 0.028 14.4 0.5 1.4 1 0 0 1 1 1 0 NB glycoprotein Chordopox_A33R PF05966.12 EJP63095.1 - 0.021 14.1 0.7 0.15 11.3 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein TMCO5 PF14992.6 EJP63095.1 - 0.03 13.9 10.4 0.52 9.8 10.4 2.2 1 1 0 1 1 1 0 TMCO5 family DUF3671 PF12420.8 EJP63095.1 - 0.031 14.4 0.1 0.053 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF3357 PF11837.8 EJP63095.1 - 0.053 14.0 0.1 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Ferritin PF00210.24 EJP63095.1 - 0.058 13.3 0.4 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Ferritin-like domain EphA2_TM PF14575.6 EJP63095.1 - 0.058 14.3 2.3 0.071 14.0 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain T2SSF PF00482.23 EJP63095.1 - 0.13 12.2 2.6 1 9.3 1.5 2.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F Picorna_P3A PF06363.11 EJP63095.1 - 0.13 12.1 0.3 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 Picornaviridae P3A protein Chordopox_A13L PF05961.11 EJP63095.1 - 0.16 12.2 1.5 0.7 10.2 1.5 2.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein ASFV_J13L PF05568.11 EJP63095.1 - 0.21 11.3 1.6 0.51 10.1 1.6 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein MCU PF04678.13 EJP63095.1 - 0.3 11.2 9.8 0.38 10.8 2.3 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Baculo_11_kDa PF06143.11 EJP63095.1 - 0.51 9.9 3.3 0.38 10.4 0.9 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family Prominin PF05478.11 EJP63095.1 - 0.76 7.7 10.8 1.6 6.6 10.7 1.5 1 1 0 1 1 1 0 Prominin RIFIN PF02009.16 EJP63095.1 - 0.78 9.6 11.0 0.47 10.3 7.8 1.8 1 1 1 2 2 2 0 Rifin Baculo_p24 PF05073.12 EJP63095.1 - 1 9.1 6.5 9.3 6.0 1.0 2.5 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Allexi_40kDa PF05549.11 EJP63095.1 - 2 7.9 10.9 0.29 10.6 2.1 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2500 PF10694.9 EJP63095.1 - 3.5 8.2 5.9 0.52 10.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) V-SNARE PF05008.15 EJP63095.1 - 8.9 6.8 15.2 0.39 11.1 1.1 4.1 2 2 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Memo PF01875.17 EJP63096.1 - 2.5e-59 200.6 0.0 3.2e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein FA_hydroxylase PF04116.13 EJP63097.1 - 2.8e-17 63.3 11.3 2.8e-17 63.3 11.3 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ras PF00071.22 EJP63099.1 - 7e-49 165.5 0.0 8.4e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP63099.1 - 2e-29 102.3 0.0 4.9e-29 101.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP63099.1 - 3.4e-10 39.7 0.0 4.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 EJP63099.1 - 0.00052 20.4 0.1 0.0029 18.0 0.1 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 EJP63099.1 - 0.00065 19.8 0.0 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EJP63099.1 - 0.0039 16.6 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EJP63099.1 - 0.01 15.0 2.0 0.63 9.1 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 EJP63099.1 - 0.015 14.7 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 EJP63099.1 - 0.028 14.3 0.1 8.8 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EJP63099.1 - 0.031 13.8 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EJP63099.1 - 0.055 13.2 0.3 0.092 12.5 0.2 1.4 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EJP63099.1 - 0.096 12.7 0.1 0.21 11.6 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EJP63099.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EJP63099.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 EJP63099.1 - 0.16 11.1 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Septin PF00735.18 EJP63099.1 - 0.18 11.0 0.5 0.28 10.4 0.1 1.5 2 0 0 2 2 2 0 Septin Nas2_N PF18265.1 EJP63100.1 - 1.3e-29 101.9 0.1 1.8e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EJP63100.1 - 1.1e-06 28.4 0.0 2.6e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EJP63100.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EJP63100.1 - 0.00025 21.4 0.0 0.00075 19.8 0.0 1.8 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 EJP63100.1 - 0.0017 18.7 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PWI PF01480.17 EJP63101.1 - 1.2e-13 51.1 0.2 3.1e-13 49.8 0.1 1.7 2 0 0 2 2 2 1 PWI domain NuA4 PF09340.10 EJP63102.1 - 7.1e-24 83.5 0.1 7.1e-24 83.5 0.1 2.0 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Uds1 PF15456.6 EJP63102.1 - 0.0078 16.4 0.4 0.13 12.4 0.2 2.1 2 0 0 2 2 2 1 Up-regulated During Septation DHR10 PF18595.1 EJP63102.1 - 0.066 13.3 9.9 0.16 12.0 1.1 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain K_channel_TID PF07941.11 EJP63102.1 - 0.12 12.9 6.6 0.1 13.1 3.4 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Peptidase_S9 PF00326.21 EJP63103.1 - 5e-57 192.8 0.1 1.4e-55 188.0 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 EJP63103.1 - 0.0034 16.1 0.0 1.8 7.1 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) PD40 PF07676.12 EJP63103.1 - 0.0078 16.1 0.0 0.029 14.3 0.0 2.0 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat DUF5111 PF17138.4 EJP63103.1 - 0.017 15.0 0.9 0.26 11.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5111) DUF2920 PF11144.8 EJP63103.1 - 0.17 11.0 0.0 0.89 8.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Bromo_TP PF07524.13 EJP63104.1 - 3.4e-09 36.6 0.1 1.9e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 EJP63104.1 - 0.00056 20.0 0.0 0.00094 19.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PPR_2 PF13041.6 EJP63105.1 - 9.8e-11 41.7 0.0 3.2e-06 27.2 0.0 4.8 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.20 EJP63105.1 - 0.00076 19.6 0.3 2.2 8.7 0.0 4.5 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 EJP63105.1 - 0.011 15.9 0.0 0.2 11.7 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_6 PF13174.6 EJP63105.1 - 0.014 16.0 2.7 56 4.7 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_1 PF12854.7 EJP63105.1 - 0.025 14.3 0.0 24 4.7 0.1 3.9 4 0 0 4 4 4 0 PPR repeat Snf7 PF03357.21 EJP63105.1 - 0.14 11.8 4.4 0.037 13.6 0.5 2.1 2 0 0 2 2 2 0 Snf7 TPR_14 PF13428.6 EJP63105.1 - 1.1 10.2 6.7 55 5.0 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RTC_insert PF05189.13 EJP63106.1 - 2.9e-30 104.8 0.0 5.3e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EJP63106.1 - 2.9e-30 105.1 0.5 3.7e-30 104.8 0.5 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF1746 PF08508.10 EJP63107.1 - 6.4e-39 132.9 3.0 9.4e-39 132.3 3.0 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) tRNA-synt_2d PF01409.20 EJP63108.1 - 1.9e-86 289.5 0.0 2.6e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EJP63108.1 - 5.5e-16 58.6 0.4 5.5e-16 58.6 0.4 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EJP63108.1 - 1.8e-06 27.5 0.0 0.002 17.6 0.0 2.8 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EJP63108.1 - 6.6e-06 26.0 3.9 6.6e-06 26.0 3.9 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 EJP63108.1 - 9.7e-05 21.6 0.2 0.0019 17.4 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF1938 PF09153.10 EJP63108.1 - 0.025 14.7 0.1 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) tRNA-synt_2b PF00587.25 EJP63108.1 - 0.16 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) G-patch PF01585.23 EJP63109.1 - 9.2e-05 22.3 0.0 0.00034 20.5 0.0 2.1 2 0 0 2 2 2 1 G-patch domain GREB1 PF15782.5 EJP63109.1 - 0.051 10.7 22.6 0.067 10.3 22.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 EJP63109.1 - 0.29 11.2 39.0 0.46 10.5 39.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region 7tm_2 PF00002.24 EJP63109.1 - 1.9 7.7 22.0 0.0075 15.6 8.0 2.6 2 1 1 3 3 3 0 7 transmembrane receptor (Secretin family) RPN13_C PF16550.5 EJP63110.1 - 0.059 13.5 0.0 22 5.3 0.0 2.9 3 1 0 3 3 3 0 UCH-binding domain FolB PF02152.18 EJP63111.1 - 1.4e-21 77.1 0.3 2.4e-16 60.3 0.1 2.6 2 1 0 2 2 2 2 Dihydroneopterin aldolase SUIM_assoc PF16619.5 EJP63111.1 - 1.2 9.2 7.8 2.3 8.4 7.8 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3605 PF12239.8 EJP63112.1 - 2.4e-56 190.3 0.1 2.9e-56 190.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.18 EJP63113.1 - 2.3e-192 639.2 0.1 2.7e-192 639.0 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 EJP63113.1 - 0.25 10.1 3.4 0.86 8.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) Glyco_transf_25 PF01755.17 EJP63114.1 - 9e-12 45.3 0.0 5.3e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-CCCH PF00642.24 EJP63115.1 - 3.5e-17 61.9 31.7 2.5e-07 30.4 0.6 5.7 5 1 1 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EJP63115.1 - 2.3e-14 52.9 33.0 1.7e-05 24.7 2.8 5.6 6 0 0 6 6 6 4 Zinc finger domain zf-CCCH_4 PF18044.1 EJP63115.1 - 8.1e-09 35.1 30.2 0.001 18.8 0.4 5.7 5 0 0 5 5 5 4 CCCH-type zinc finger Torus PF16131.5 EJP63115.1 - 5.2e-07 30.3 23.2 0.0068 17.1 0.3 5.5 2 1 4 6 6 6 4 Torus domain DUF1776 PF08643.10 EJP63116.1 - 3.9e-101 338.3 0.0 4.9e-101 338.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MT0933_antitox PF14013.6 EJP63116.1 - 0.026 14.8 0.1 0.049 13.9 0.1 1.4 1 0 0 1 1 1 0 MT0933-like antitoxin protein Amidase PF01425.21 EJP63117.1 - 1.3e-89 301.3 0.0 1.7e-89 300.9 0.0 1.1 1 0 0 1 1 1 1 Amidase PCMT PF01135.19 EJP63118.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) STAS_2 PF13466.6 EJP63118.1 - 0.03 14.6 3.0 0.031 14.6 0.1 2.4 3 0 0 3 3 3 0 STAS domain SH3_4 PF06347.13 EJP63118.1 - 0.23 11.3 1.5 0.42 10.5 0.7 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain WLM PF08325.10 EJP63119.1 - 3e-43 148.1 0.0 3.6e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EJP63119.1 - 4.4e-05 22.7 0.8 7e-05 22.1 0.8 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 EJP63119.1 - 0.054 12.9 0.2 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 EJP63119.1 - 0.094 12.8 1.0 0.17 11.9 1.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon HATPase_c PF02518.26 EJP63120.1 - 2.6e-28 98.7 0.2 5.7e-28 97.7 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EJP63120.1 - 5.7e-22 77.5 0.0 2.2e-21 75.7 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EJP63120.1 - 1.4e-21 76.7 0.1 4.2e-21 75.2 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 EJP63120.1 - 3.1e-15 56.2 0.1 1e-14 54.5 0.1 2.0 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EJP63120.1 - 1.3e-12 47.9 0.8 4.8e-06 26.8 0.1 4.6 4 0 0 4 4 4 2 PAS fold PAS PF00989.25 EJP63120.1 - 1.3e-08 34.8 0.0 0.0026 17.7 0.0 3.9 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 EJP63120.1 - 1.7e-08 34.6 0.0 0.0019 18.5 0.0 4.2 4 0 0 4 4 4 2 PAS domain PAS_8 PF13188.7 EJP63120.1 - 0.0048 16.9 0.5 0.21 11.7 0.1 3.6 4 0 0 4 4 4 1 PAS domain HATPase_c_3 PF13589.6 EJP63120.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NEAT PF05031.12 EJP63120.1 - 0.12 13.0 0.7 7.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Iron Transport-associated domain NAD_binding_6 PF08030.12 EJP63121.1 - 2.4e-23 83.0 0.0 4.2e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EJP63121.1 - 1.3e-22 79.9 0.0 2.6e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EJP63121.1 - 1.9e-20 73.2 16.4 2.3e-20 73.0 10.0 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EJP63121.1 - 0.088 13.5 0.0 2.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EJP63121.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain C2 PF00168.30 EJP63122.1 - 4.9e-22 78.2 0.0 7e-12 45.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 EJP63122.1 - 0.0022 17.5 0.2 0.074 12.5 0.0 2.2 2 0 0 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain RXT2_N PF08595.11 EJP63122.1 - 1.5 8.9 7.2 0.32 11.0 2.7 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Mpv17_PMP22 PF04117.12 EJP63123.1 - 7.1e-26 90.2 2.8 1.5e-25 89.2 2.8 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family E1-E2_ATPase PF00122.20 EJP63124.1 - 0.21 11.1 1.4 0.25 10.8 0.3 1.5 2 0 0 2 2 2 0 E1-E2 ATPase Arteri_Gl PF00951.18 EJP63124.1 - 0.25 11.1 2.0 0.44 10.3 2.0 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein F-box PF00646.33 EJP63125.1 - 0.072 13.0 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain DUF1713 PF08213.11 EJP63126.1 - 2.6e-08 33.6 21.0 2.6e-08 33.6 21.0 2.0 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 EJP63126.1 - 0.027 15.2 0.0 0.069 13.9 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial protein Pet20 GNAT_acetyltr_2 PF13718.6 EJP63127.1 - 8e-98 326.4 0.0 1.4e-97 325.6 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EJP63127.1 - 2.2e-89 299.2 0.0 3.5e-89 298.5 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EJP63127.1 - 5.9e-65 218.4 0.1 2.3e-64 216.5 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EJP63127.1 - 8e-33 112.2 0.3 3.5e-32 110.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EJP63127.1 - 6.8e-05 22.7 0.2 0.021 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EJP63127.1 - 0.0036 17.6 0.0 0.13 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.7 EJP63127.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Codanin-1_C PF15296.6 EJP63128.1 - 0.05 13.7 5.3 0.1 12.7 5.3 1.4 1 0 0 1 1 1 0 Codanin-1 C-terminus CLIP PF12032.8 EJP63128.1 - 0.095 13.0 0.9 0.2 12.0 0.9 1.6 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases Abhydrolase_6 PF12697.7 EJP63129.1 - 5.4e-07 30.4 10.0 9.6e-07 29.6 10.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 EJP63129.1 - 1.1e-06 28.2 1.9 0.00023 20.6 1.9 2.2 1 1 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 EJP63129.1 - 7.9e-05 22.0 0.5 0.051 12.8 0.5 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EJP63129.1 - 0.0001 21.8 0.1 0.0028 17.1 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EJP63129.1 - 0.00097 18.9 0.3 0.25 10.9 0.5 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EJP63129.1 - 0.0023 17.6 0.1 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF4448 PF14610.6 EJP63130.1 - 3.9e-38 131.1 0.0 5.3e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CBM_19 PF03427.13 EJP63131.1 - 0.011 15.7 6.8 0.025 14.6 6.8 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Nup188_C PF18378.1 EJP63131.1 - 0.043 12.7 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain Conotoxin PF02950.17 EJP63131.1 - 0.19 12.7 4.5 0.38 11.8 4.5 1.6 1 1 0 1 1 1 0 Conotoxin AA_kinase PF00696.28 EJP63132.1 - 1.4e-31 109.9 0.3 1.8e-31 109.6 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family FMO-like PF00743.19 EJP63133.1 - 1.4e-10 40.2 0.0 2.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EJP63133.1 - 6.4e-09 35.4 0.0 1.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EJP63133.1 - 6.5e-07 28.9 0.0 2.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP63133.1 - 0.00013 22.1 0.0 0.00043 20.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP63133.1 - 0.00028 20.2 0.0 0.0007 18.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP63133.1 - 0.0066 16.1 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EJP63133.1 - 0.041 13.1 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Fox-1_C PF12414.8 EJP63133.1 - 0.059 13.8 1.0 0.18 12.2 0.1 2.2 2 1 0 2 2 2 0 Calcitonin gene-related peptide regulator C terminal Pyr_redox_3 PF13738.6 EJP63134.1 - 5.1e-12 45.7 0.0 1e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP63134.1 - 1.9e-09 37.6 0.0 1.3e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EJP63134.1 - 2.1e-09 36.4 0.0 7.2e-09 34.6 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EJP63134.1 - 4.6e-09 35.9 0.0 1.3e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP63134.1 - 6.2e-07 28.9 0.2 9.4e-06 25.0 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EJP63134.1 - 9.7e-06 25.0 0.0 0.00024 20.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EJP63134.1 - 0.00014 21.6 5.4 0.00038 20.1 1.0 2.8 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP63134.1 - 0.00017 22.1 0.2 0.23 12.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP63134.1 - 0.0019 17.4 0.2 0.028 13.5 0.1 2.8 4 0 0 4 4 4 1 FAD binding domain Shikimate_DH PF01488.20 EJP63134.1 - 0.018 15.1 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 EJP63134.1 - 0.035 13.4 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EJP63134.1 - 0.042 13.2 0.2 0.085 12.2 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP63134.1 - 0.051 12.6 0.3 12 4.8 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein MCRA PF06100.11 EJP63134.1 - 0.066 12.0 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 MCRA family FAD_binding_3 PF01494.19 EJP63134.1 - 0.11 11.7 0.1 0.91 8.7 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.15 EJP63134.1 - 0.19 10.2 0.0 0.47 8.9 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 EJP63134.1 - 0.26 11.2 2.0 4.3 7.3 0.1 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding Fe-ADH PF00465.19 EJP63135.1 - 1.6e-16 60.1 0.0 2.2e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EJP63135.1 - 4.9e-05 23.2 0.0 9.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase RuvX PF03652.15 EJP63135.1 - 0.078 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction resolvase ANAPC4_WD40 PF12894.7 EJP63136.1 - 6.2e-06 26.4 0.0 0.0061 16.8 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJP63136.1 - 0.003 18.3 8.2 2.8 9.0 0.1 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.8 EJP63136.1 - 0.021 13.5 0.0 0.067 11.8 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Mpp10 PF04006.12 EJP63136.1 - 0.071 11.6 16.7 0.094 11.1 16.7 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 EJP63136.1 - 0.073 11.6 21.5 0.1 11.1 21.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EJP63136.1 - 0.46 8.6 17.9 0.62 8.2 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 EJP63136.1 - 0.47 10.5 22.4 0.74 9.9 22.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 EJP63136.1 - 0.53 10.0 21.1 0.85 9.3 21.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 EJP63136.1 - 0.55 8.5 18.0 0.78 8.0 18.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EJP63136.1 - 1.2 7.2 25.6 1.6 6.7 25.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 EJP63136.1 - 1.2 7.1 4.0 1.6 6.7 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 EJP63136.1 - 1.2 8.0 3.8 1.8 7.5 3.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 EJP63136.1 - 3.6 6.3 7.2 4.7 5.9 7.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 EJP63136.1 - 9.2 5.6 22.0 13 5.0 22.0 1.1 1 0 0 1 1 1 0 SDA1 Glyco_hydro_18 PF00704.28 EJP63137.1 - 2e-48 165.7 0.0 2.2e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.6 EJP63137.1 - 0.055 13.4 0.1 0.083 12.8 0.1 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 GDPD PF03009.17 EJP63138.1 - 2e-13 50.7 0.0 2.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PAF-AH_p_II PF03403.13 EJP63139.1 - 5e-11 41.7 0.0 8.6e-09 34.4 0.0 2.3 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EJP63139.1 - 8.2e-05 21.6 0.0 0.00023 20.1 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EJP63139.1 - 0.0034 18.0 0.5 0.0034 18.0 0.5 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EJP63139.1 - 0.02 14.7 0.0 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EJP63139.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans_2 PF11951.8 EJP63140.1 - 1.7e-09 37.0 0.4 4.7e-05 22.4 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63140.1 - 7e-07 29.3 8.2 1.7e-06 28.1 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3400 PF11880.8 EJP63140.1 - 0.14 11.8 0.1 17 5.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3400) MARVEL PF01284.23 EJP63141.1 - 6.6e-16 58.6 16.2 7.9e-16 58.4 16.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain TssN PF17555.2 EJP63141.1 - 0.083 12.3 1.9 0.11 11.8 1.9 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN Sigma_reg_N PF13800.6 EJP63141.1 - 2.5 8.4 4.1 0.45 10.8 0.3 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal FMN_bind PF04205.14 EJP63142.1 - 0.077 13.6 1.8 0.13 12.8 1.8 1.5 1 0 0 1 1 1 0 FMN-binding domain Helicase_C PF00271.31 EJP63143.1 - 9.5e-11 42.0 0.0 7.5e-10 39.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP63143.1 - 6.9e-06 25.9 0.6 1.5e-05 24.9 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJP63143.1 - 3.7e-05 24.0 0.1 8.9e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EJP63143.1 - 0.00027 21.0 0.1 0.00071 19.6 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HA2 PF04408.23 EJP63143.1 - 0.0011 19.2 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_RecD PF05127.14 EJP63143.1 - 0.031 14.1 0.2 0.065 13.1 0.2 1.5 1 0 0 1 1 1 0 Helicase HNH_2 PF13391.6 EJP63144.1 - 3e-11 43.3 0.0 8e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease MARVEL PF01284.23 EJP63146.1 - 0.0024 17.9 18.3 0.0034 17.4 18.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.11 EJP63146.1 - 1.5 8.7 18.8 2.5 7.9 12.8 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4834 PF16118.5 EJP63146.1 - 2.9 8.9 0.0 2.9 8.9 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) DUF5337 PF17272.2 EJP63146.1 - 4.4 7.2 14.4 0.33 10.8 5.3 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5337) Wzy_C PF04932.15 EJP63146.1 - 5.7 6.5 11.3 20 4.8 11.3 1.9 1 1 0 1 1 1 0 O-Antigen ligase DUF4293 PF14126.6 EJP63146.1 - 7.8 6.7 12.6 1.2 9.3 7.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Cellulase PF00150.18 EJP63147.1 - 2.3e-32 112.6 0.0 2.7e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CRT10 PF08728.10 EJP63148.1 - 1.6e-17 63.0 0.0 4.6e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 CRT10 Nop14 PF04147.12 EJP63148.1 - 0.19 9.9 17.2 0.26 9.5 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EJP63148.1 - 0.2 11.0 18.2 0.54 9.5 18.2 1.7 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 EJP63148.1 - 4.1 6.7 16.3 6.8 6.0 16.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 EJP63148.1 - 4.3 6.7 18.5 6.4 6.1 18.5 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EJP63148.1 - 5.7 4.9 29.9 8.1 4.4 29.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ammonium_transp PF00909.21 EJP63149.1 - 3.7e-116 388.1 30.0 4.3e-116 387.9 30.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.8 EJP63149.1 - 6.4 6.9 7.9 20 5.3 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) His_Phos_2 PF00328.22 EJP63150.1 - 1.2e-46 159.8 0.0 1.6e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TauD PF02668.16 EJP63150.1 - 1.6e-26 93.7 0.1 2.9e-26 92.9 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pex14_N PF04695.13 EJP63150.1 - 0.0045 17.7 0.8 0.0081 16.8 0.8 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CsiD PF08943.10 EJP63150.1 - 0.13 11.4 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 CsiD Pkinase PF00069.25 EJP63152.1 - 0.0039 16.6 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SUIM_assoc PF16619.5 EJP63153.1 - 0.016 15.3 4.0 0.034 14.2 4.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SWIM PF04434.17 EJP63153.1 - 0.4 10.4 0.1 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 SWIM zinc finger Med3 PF11593.8 EJP63153.1 - 1.1 8.4 8.1 1.7 7.7 8.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.22 EJP63154.1 - 3.5e-18 65.2 0.2 7.3e-18 64.2 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJP63154.1 - 0.00021 20.9 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJP63154.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif HhH-GPD PF00730.25 EJP63155.1 - 0.0013 19.1 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SURF4 PF02077.15 EJP63156.1 - 3.2e-97 325.3 7.6 3.7e-97 325.1 7.6 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 EJP63156.1 - 0.9 9.5 5.3 2.8 7.9 1.5 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DSPn PF14671.6 EJP63157.1 - 4.7e-41 140.5 0.0 9.9e-39 133.0 0.0 2.5 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EJP63157.1 - 4.3e-16 58.9 0.0 9.6e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJP63157.1 - 7.6e-06 25.7 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pcc1 PF09341.10 EJP63158.1 - 1.2e-32 111.9 0.1 1.4e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 HLH PF00010.26 EJP63159.1 - 1.1e-11 44.5 0.0 2.5e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 EJP63159.1 - 0.09 13.0 1.7 0.17 12.1 1.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 EJP63159.1 - 0.1 12.7 0.9 0.3 11.2 0.9 1.7 1 0 0 1 1 1 0 bZIP transcription factor Kelch_4 PF13418.6 EJP63160.1 - 7.5e-05 22.7 0.8 0.16 12.0 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain TMEM154 PF15102.6 EJP63160.1 - 0.00012 22.0 1.1 0.00028 20.8 1.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.18 EJP63160.1 - 0.00056 20.1 0.7 0.00056 20.1 0.7 1.8 2 0 0 2 2 2 1 Glycophorin A DUF4448 PF14610.6 EJP63160.1 - 0.0007 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Kelch_6 PF13964.6 EJP63160.1 - 0.0027 17.9 0.2 5.5 7.4 0.0 3.9 3 0 0 3 3 3 1 Kelch motif AJAP1_PANP_C PF15298.6 EJP63160.1 - 0.0093 16.2 5.7 0.019 15.2 5.7 1.5 1 0 0 1 1 1 1 AJAP1/PANP C-terminus DUF5305 PF17231.2 EJP63160.1 - 0.015 14.7 1.7 0.027 13.9 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Tox-GHH2 PF15635.6 EJP63160.1 - 0.068 13.7 0.2 0.22 12.1 0.2 1.9 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 Amnionless PF14828.6 EJP63160.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless Alpha_GJ PF03229.13 EJP63160.1 - 0.25 11.9 9.5 0.42 11.2 4.6 2.9 2 0 0 2 2 2 0 Alphavirus glycoprotein J Mucin PF01456.17 EJP63160.1 - 3.1 7.8 24.7 1.3 9.0 21.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein TAP_C PF03943.13 EJP63161.1 - 4.8e-15 54.9 0.1 1.3e-14 53.5 0.1 1.8 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.7 EJP63161.1 - 5e-06 26.8 0.1 0.0035 17.7 0.0 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 EJP63161.1 - 0.00062 20.3 0.0 0.094 13.3 0.0 2.4 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 EJP63161.1 - 0.00076 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat RRM_9 PF18444.1 EJP63161.1 - 0.00085 19.1 0.0 0.0086 15.9 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif Phage_30_3 PF08010.11 EJP63161.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 ResIII PF04851.15 EJP63162.1 - 4.7e-23 82.1 0.0 9.2e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EJP63162.1 - 1.7e-21 76.7 0.0 4e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP63162.1 - 6.1e-17 61.9 0.0 1.7e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EJP63162.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF1772 PF08592.11 EJP63162.1 - 0.0035 17.7 5.8 0.044 14.1 7.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) AAA_22 PF13401.6 EJP63162.1 - 0.023 15.0 0.0 0.15 12.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain Ank_2 PF12796.7 EJP63163.1 - 2.4e-43 146.6 6.1 7.6e-13 48.9 0.0 9.9 6 3 3 10 10 10 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP63163.1 - 2.9e-30 100.9 6.0 0.054 14.1 0.0 13.2 14 0 0 14 14 14 8 Ankyrin repeat Ank_4 PF13637.6 EJP63163.1 - 2.6e-27 94.8 4.7 0.00015 22.2 0.0 10.0 8 3 2 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 EJP63163.1 - 6e-25 86.5 12.6 0.0018 18.6 0.0 10.6 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 EJP63163.1 - 2.2e-22 78.8 9.4 6e-05 23.3 0.0 9.7 11 0 0 11 11 11 5 Ankyrin repeats (many copies) Cutinase PF01083.22 EJP63164.1 - 4.4e-40 137.5 0.8 5.8e-40 137.1 0.8 1.2 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 EJP63164.1 - 0.0071 16.2 0.0 0.0099 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) LIP PF03583.14 EJP63164.1 - 0.012 15.0 0.1 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_9 PF10081.9 EJP63164.1 - 0.024 13.7 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family PE-PPE PF08237.11 EJP63164.1 - 0.073 12.6 0.1 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 PE-PPE domain DUF2974 PF11187.8 EJP63164.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1275 PF06912.11 EJP63165.1 - 2.2e-44 151.7 15.2 2.6e-44 151.5 15.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) YbjM PF11045.8 EJP63165.1 - 9.2e-05 22.6 2.1 0.00014 22.0 1.4 1.7 2 0 0 2 2 2 1 Putative inner membrane protein of Enterobacteriaceae Myc_target_1 PF15179.6 EJP63165.1 - 0.032 14.1 0.3 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Myc target protein 1 RseC_MucC PF04246.12 EJP63165.1 - 8.9 6.3 10.6 9.6 6.2 0.7 3.0 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DEAD PF00270.29 EJP63166.1 - 2.4e-22 79.6 0.0 6.1e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP63166.1 - 1.7e-16 60.6 0.0 3.9e-14 52.9 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EJP63166.1 - 2.1e-15 57.2 6.1 2.1e-15 57.2 6.1 2.6 3 0 0 3 3 3 1 RecQ zinc-binding RQC PF09382.10 EJP63166.1 - 2.8e-12 46.4 0.0 5.7e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 EJP63166.1 - 7.1e-10 39.2 0.0 2.9e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HRDC PF00570.23 EJP63166.1 - 0.0027 17.7 0.0 0.0082 16.1 0.0 1.9 1 0 0 1 1 1 1 HRDC domain FTA2 PF13095.6 EJP63166.1 - 0.012 15.2 0.2 0.29 10.7 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 KAR9 PF08580.10 EJP63167.1 - 1.6e-163 545.9 0.3 1.6e-163 545.9 0.3 2.5 2 1 1 3 3 3 1 Yeast cortical protein KAR9 PilJ PF13675.6 EJP63167.1 - 0.0012 18.8 1.4 0.89 9.6 0.2 3.7 2 2 0 2 2 2 2 Type IV pili methyl-accepting chemotaxis transducer N-term GntR PF00392.21 EJP63168.1 - 0.085 12.5 0.3 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family VTC PF09359.10 EJP63169.1 - 1.3e-98 329.7 0.2 3.1e-98 328.6 0.0 1.6 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EJP63169.1 - 1.9e-14 53.9 1.7 3.6e-14 52.9 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 EJP63169.1 - 4.3e-13 49.9 6.4 5.4e-06 26.6 0.0 4.0 3 1 1 4 4 4 3 SPX domain TrmB PF01978.19 EJP63169.1 - 0.014 15.2 0.3 0.044 13.7 0.3 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EJP63169.1 - 0.016 15.1 0.1 0.049 13.5 0.2 1.8 2 0 0 2 2 2 0 MarR family 7TMR-DISM_7TM PF07695.11 EJP63169.1 - 0.059 13.3 4.6 0.092 12.6 4.6 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling Fe_dep_repress PF01325.19 EJP63169.1 - 0.063 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Angiomotin_C PF12240.8 EJP63169.1 - 0.22 11.0 2.3 0.67 9.5 2.1 1.8 2 0 0 2 2 2 0 Angiomotin C terminal Hexokinase_2 PF03727.16 EJP63171.1 - 7.7e-83 277.6 0.0 1.1e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EJP63171.1 - 4.4e-73 245.4 0.0 9.8e-73 244.3 0.0 1.5 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.21 EJP63171.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Semialdhyde_dh PF01118.24 EJP63172.1 - 8.7e-30 103.7 0.0 2.6e-29 102.1 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EJP63172.1 - 0.046 13.9 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Ribophorin_I PF04597.14 EJP63173.1 - 1.6e-146 489.0 0.4 1.8e-146 488.8 0.4 1.0 1 0 0 1 1 1 1 Ribophorin I Kdo PF06293.14 EJP63174.1 - 1.7e-05 24.3 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP63174.1 - 0.00031 20.8 0.1 0.02 14.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.11 EJP63174.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF3328 PF11807.8 EJP63176.1 - 6.4e-23 81.7 0.0 8.6e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_membrane PF00664.23 EJP63177.1 - 1.3e-65 221.8 31.2 3.3e-36 125.4 5.2 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP63177.1 - 1.1e-46 158.8 0.0 1.3e-29 103.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP63177.1 - 1.3e-08 34.6 0.0 0.042 13.3 0.0 3.8 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EJP63177.1 - 7.1e-05 22.9 1.5 0.046 13.8 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EJP63177.1 - 9e-05 22.9 0.8 0.014 15.8 0.3 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EJP63177.1 - 0.00015 21.5 0.2 0.55 10.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP63177.1 - 0.0006 20.1 0.9 0.45 10.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EJP63177.1 - 0.0037 17.1 1.1 2.8 7.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EJP63177.1 - 0.0073 16.2 0.1 3.4 7.6 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EJP63177.1 - 0.0078 15.9 0.2 1.3 8.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EJP63177.1 - 0.0096 15.2 0.7 4 6.7 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 EJP63177.1 - 0.022 14.5 1.4 7.1 6.3 0.0 3.3 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 EJP63177.1 - 0.025 14.7 6.2 0.33 11.0 0.1 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_7 PF12775.7 EJP63177.1 - 0.04 13.4 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EJP63177.1 - 0.05 13.2 0.1 0.6 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EJP63177.1 - 0.071 12.0 0.1 5.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 EJP63177.1 - 0.15 12.0 1.8 5.9 6.8 0.1 3.1 3 0 0 3 3 3 0 NACHT domain ATP_bind_1 PF03029.17 EJP63177.1 - 0.29 10.9 1.3 24 4.6 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 EJP63177.1 - 0.41 11.1 6.0 2.4 8.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EJP63177.1 - 1.2 9.2 7.0 2.6 8.1 0.4 3.1 3 0 0 3 3 3 0 Dynamin family IstB_IS21 PF01695.17 EJP63177.1 - 5.2 6.8 5.9 13 5.5 0.1 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein 2OG-FeII_Oxy_3 PF13640.6 EJP63178.1 - 1e-08 36.0 0.1 2.2e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 EJP63179.1 - 8.2e-25 87.7 0.0 3.9e-24 85.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP63179.1 - 6.3e-09 35.5 0.0 3.9e-07 29.6 0.0 3.0 2 2 0 2 2 2 1 Protein tyrosine kinase NAGLU PF05089.12 EJP63180.1 - 1.3e-128 428.7 4.3 2e-128 428.1 4.3 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 EJP63180.1 - 9.8e-66 222.0 0.5 1.6e-65 221.3 0.5 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 EJP63180.1 - 4.4e-17 61.6 0.0 9.6e-17 60.5 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain ANAPC4_WD40 PF12894.7 EJP63181.1 - 9.5e-09 35.4 0.5 0.12 12.7 0.0 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJP63181.1 - 3.4e-05 24.5 12.2 0.0032 18.3 0.5 5.1 4 1 0 4 4 4 2 WD domain, G-beta repeat PD40 PF07676.12 EJP63181.1 - 0.014 15.4 6.3 0.95 9.5 0.0 4.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EJP63181.1 - 0.023 13.4 0.1 0.19 10.4 0.0 2.4 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Zn_clus PF00172.18 EJP63184.1 - 9e-08 32.1 7.3 2e-07 31.0 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP63184.1 - 3.1e-07 29.5 0.0 4.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 EJP63185.1 - 2.6e-67 226.7 0.0 3.1e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 EJP63185.1 - 0.13 13.2 0.1 0.35 11.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) Cation_ATPase_C PF00689.21 EJP63186.1 - 1.1e-44 152.3 10.2 1.1e-44 152.3 10.2 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EJP63186.1 - 7.6e-35 120.1 2.6 7.6e-35 120.1 2.6 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EJP63186.1 - 7.3e-23 82.0 0.3 1.4e-22 81.0 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJP63186.1 - 3.7e-21 75.0 0.1 7.2e-21 74.1 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EJP63186.1 - 4e-08 32.8 0.3 2.4e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP63186.1 - 7.8e-05 22.5 0.2 0.0011 18.8 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP63186.1 - 0.0061 17.0 0.0 0.04 14.3 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase cobW PF02492.19 EJP63187.1 - 1.2e-47 161.8 7.9 1.2e-44 152.0 7.9 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EJP63187.1 - 7.1e-18 64.3 0.1 1.3e-13 50.7 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 EJP63187.1 - 6.2e-05 22.1 0.3 0.0047 16.0 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 EJP63187.1 - 0.0053 16.5 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PI3K_1B_p101 PF10486.9 EJP63187.1 - 0.007 14.2 5.5 0.011 13.6 5.5 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MobB PF03205.14 EJP63187.1 - 0.0074 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.27 EJP63187.1 - 0.0094 15.5 3.6 0.58 9.7 2.4 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain TsaE PF02367.17 EJP63187.1 - 0.0094 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PTPRCAP PF15713.5 EJP63187.1 - 0.011 16.1 11.7 0.028 14.7 11.7 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated AAA_16 PF13191.6 EJP63187.1 - 0.013 15.9 3.6 0.023 15.1 0.4 2.7 2 1 0 2 2 2 0 AAA ATPase domain Sigma70_ner PF04546.13 EJP63187.1 - 0.015 15.2 1.8 0.015 15.2 1.8 2.4 3 0 0 3 3 2 0 Sigma-70, non-essential region AAA_33 PF13671.6 EJP63187.1 - 0.019 15.1 0.0 0.082 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain YL1 PF05764.13 EJP63187.1 - 0.023 14.8 10.2 0.057 13.5 10.2 1.7 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 EJP63187.1 - 0.031 13.7 12.3 0.056 12.9 12.3 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EJP63187.1 - 0.052 12.9 15.7 0.1 11.9 15.7 1.4 1 0 0 1 1 1 0 BUD22 AAA_29 PF13555.6 EJP63187.1 - 0.071 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Apt1 PF10351.9 EJP63187.1 - 0.098 11.5 5.9 0.15 10.9 5.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 EJP63187.1 - 0.13 10.3 8.7 0.21 9.6 8.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TEX19 PF15553.6 EJP63187.1 - 0.13 12.2 2.0 0.31 11.0 2.0 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 RRN3 PF05327.11 EJP63187.1 - 0.28 9.7 9.0 0.6 8.6 9.0 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.6 EJP63187.1 - 0.3 10.8 8.9 0.56 9.9 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nop14 PF04147.12 EJP63187.1 - 0.37 8.9 16.8 0.63 8.2 16.8 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_18 PF13238.6 EJP63187.1 - 0.4 11.2 2.2 0.51 10.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain CDC45 PF02724.14 EJP63187.1 - 0.54 8.5 16.0 0.92 7.7 16.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EJP63187.1 - 1.5 7.5 6.6 2.3 6.9 6.6 1.1 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 EJP63187.1 - 1.8 7.9 19.1 4.9 6.5 19.1 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDK2AP PF09806.9 EJP63187.1 - 3 7.9 8.1 5.1 7.1 8.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein OPT PF03169.15 EJP63188.1 - 2.6e-170 568.1 56.9 3e-170 567.9 56.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_Gp23 PF10669.9 EJP63188.1 - 0.75 10.1 3.1 2.8 8.3 0.0 2.9 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) DUF1688 PF07958.11 EJP63190.1 - 3.5e-180 599.2 0.0 4e-180 599.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) 60KD_IMP PF02096.20 EJP63191.1 - 4.9e-12 46.1 0.5 4.9e-12 46.1 0.5 1.7 2 0 0 2 2 2 1 60Kd inner membrane protein TOM13 PF08219.11 EJP63192.1 - 5e-37 125.7 0.0 6.4e-37 125.4 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SNF2_N PF00176.23 EJP63194.1 - 5.1e-48 163.6 0.2 1.6e-46 158.6 0.0 2.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP63194.1 - 3.3e-16 59.6 0.0 8.2e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP63194.1 - 6.4e-08 32.8 0.6 2.1e-07 31.1 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EJP63194.1 - 4.8e-05 23.1 12.8 4.8e-05 23.1 12.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP63194.1 - 0.0046 16.8 11.4 0.0046 16.8 11.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EJP63194.1 - 0.0077 15.2 0.0 0.027 13.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 EJP63194.1 - 0.0095 16.3 14.0 0.0095 16.3 14.0 2.5 2 0 0 2 2 2 1 Ring finger domain DEAD PF00270.29 EJP63194.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EJP63194.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-Nse PF11789.8 EJP63194.1 - 1.1 9.1 6.0 3.5 7.5 6.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 EJP63194.1 - 1.3 8.9 19.9 0.019 14.8 12.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 EJP63194.1 - 2.4 8.3 10.2 1.3 9.1 2.1 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_UBOX PF13445.6 EJP63194.1 - 4.9 7.3 13.0 15 5.7 13.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger LRR_6 PF13516.6 EJP63195.1 - 9.5e-08 31.5 0.3 0.062 13.4 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich repeat SR-25 PF10500.9 EJP63195.1 - 0.0056 16.3 7.7 0.0056 16.3 7.7 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein LRR_4 PF12799.7 EJP63195.1 - 0.035 14.5 0.1 46 4.6 0.0 4.5 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) USP19_linker PF16602.5 EJP63195.1 - 0.71 10.4 4.4 1.2 9.7 2.3 2.2 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase Lipase_3 PF01764.25 EJP63196.1 - 1.9e-31 108.8 0.0 3.3e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EJP63196.1 - 0.00012 22.8 0.1 0.00016 22.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP63196.1 - 0.0036 16.6 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase3_N PF03893.16 EJP63196.1 - 0.0061 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region Glyco_hydro_3_C PF01915.22 EJP63198.1 - 1.8e-46 158.7 0.1 5.3e-46 157.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EJP63198.1 - 4.6e-46 157.7 0.0 8.1e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EJP63198.1 - 1.7e-21 76.1 0.0 3.1e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 EJP63198.1 - 0.077 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 CARDB Ribosomal_L34 PF00468.17 EJP63199.1 - 6.4e-11 42.1 13.0 1.1e-10 41.3 13.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 NTF2 PF02136.20 EJP63200.1 - 0.046 14.3 1.3 0.39 11.3 1.3 2.0 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain tRNA-synt_1g PF09334.11 EJP63201.1 - 7.7e-92 308.0 1.0 5.6e-91 305.2 0.4 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EJP63201.1 - 1.2e-21 76.6 2.7 1.4e-10 40.1 0.0 3.1 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EJP63201.1 - 4.3e-09 36.1 0.0 7.6e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EJP63201.1 - 0.0031 17.5 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DALR_2 PF09190.11 EJP63201.1 - 0.11 13.0 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 DALR domain Acetyltransf_3 PF13302.7 EJP63202.1 - 7.3e-28 98.0 0.0 9.4e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP63202.1 - 1.9e-05 24.5 0.1 0.0095 15.9 0.1 2.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EJP63202.1 - 0.00012 22.2 0.1 0.0015 18.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EJP63202.1 - 0.00057 19.6 1.3 0.021 14.5 1.3 2.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP63202.1 - 0.0044 17.4 0.4 0.0091 16.4 0.4 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GrpB PF04229.14 EJP63203.1 - 9.1e-51 172.2 0.0 1.1e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 GrpB protein PLA2G12 PF06951.11 EJP63204.1 - 7.8e-10 39.0 11.7 7.8e-10 39.0 11.7 2.5 3 0 0 3 3 3 1 Group XII secretory phospholipase A2 precursor (PLA2G12) F-box-like PF12937.7 EJP63205.1 - 0.12 12.2 3.6 0.21 11.5 0.5 3.1 2 2 0 2 2 2 0 F-box-like TFR_dimer PF04253.15 EJP63206.1 - 4.1e-18 65.6 0.0 7.3e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EJP63206.1 - 5.6e-15 55.6 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EJP63206.1 - 6e-05 23.0 0.0 0.0003 20.7 0.0 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EJP63206.1 - 0.16 11.7 0.0 0.64 9.7 0.0 1.8 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 TauD PF02668.16 EJP63207.1 - 3.1e-14 53.4 1.4 6.7e-14 52.3 1.4 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EJP63207.1 - 0.00022 20.4 0.0 0.00061 19.0 0.0 1.6 2 0 0 2 2 2 1 CsiD MFS_1 PF07690.16 EJP63208.1 - 5e-34 117.8 37.9 3.8e-32 111.6 22.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP63208.1 - 7.5e-16 58.0 23.7 9.4e-16 57.7 12.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Methyltransf_23 PF13489.6 EJP63208.1 - 9.2e-11 41.8 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP63208.1 - 4.9e-10 39.9 0.0 1.1e-09 38.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP63208.1 - 1.4e-09 38.6 0.0 2.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP63208.1 - 1.4e-08 35.4 0.0 3.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRI12 PF06609.13 EJP63208.1 - 4.2e-06 25.5 6.9 6.3e-06 24.9 6.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_31 PF13847.6 EJP63208.1 - 8.7e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1_like PF12832.7 EJP63208.1 - 0.0004 19.3 10.2 0.09 11.6 9.1 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 EJP63208.1 - 2.9 6.2 18.1 0.029 12.8 7.1 2.6 4 0 0 4 4 4 0 Transmembrane secretion effector DUF2530 PF10745.9 EJP63208.1 - 3.6 7.9 9.6 0.14 12.4 1.3 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2530) Pro-kuma_activ PF09286.11 EJP63209.1 - 7.8e-42 142.9 0.0 1.9e-41 141.7 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP63209.1 - 0.018 14.3 0.0 0.051 12.8 0.0 1.6 1 1 0 1 1 1 0 Subtilase family ABC_tran PF00005.27 EJP63210.1 - 3e-47 160.6 0.0 1e-28 100.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP63210.1 - 1.4e-32 113.4 15.2 4.9e-24 85.4 5.0 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP63210.1 - 3.6e-09 36.4 0.0 0.0038 16.7 0.3 4.6 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EJP63210.1 - 7.2e-05 23.2 0.2 0.089 13.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EJP63210.1 - 0.00013 21.9 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EJP63210.1 - 0.00017 21.3 0.8 0.064 13.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EJP63210.1 - 0.00036 20.8 0.3 1 9.6 0.1 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EJP63210.1 - 0.0011 19.1 0.1 0.033 14.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 EJP63210.1 - 0.0014 17.6 0.9 0.34 9.8 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 EJP63210.1 - 0.002 18.7 0.8 3.5 8.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 EJP63210.1 - 0.0057 16.2 0.5 0.9 9.1 0.0 3.3 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 EJP63210.1 - 0.0099 15.0 0.0 3.6 6.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 EJP63210.1 - 0.015 15.1 0.3 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase PF06745.13 EJP63210.1 - 0.038 13.3 0.9 0.084 12.2 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EJP63210.1 - 0.051 13.3 1.1 2.9 7.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EJP63210.1 - 0.051 13.3 6.3 1.4 8.7 0.2 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain DUF2075 PF09848.9 EJP63210.1 - 0.056 12.7 0.6 0.89 8.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 EJP63210.1 - 0.063 13.0 2.6 6.9 6.4 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein SbcCD_C PF13558.6 EJP63210.1 - 0.063 13.5 0.0 7.1 6.9 0.0 3.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 EJP63210.1 - 0.11 12.6 2.5 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_10 PF12846.7 EJP63210.1 - 0.11 11.3 0.0 13 4.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.22 EJP63210.1 - 0.15 12.4 0.2 22 5.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase MeaB PF03308.16 EJP63210.1 - 0.22 10.5 0.8 0.35 9.8 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EJP63210.1 - 0.37 10.8 3.7 15 5.7 0.2 3.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Gas_vesicle_C PF01304.17 EJP63210.1 - 0.47 10.5 4.1 0.94 9.5 4.1 1.5 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain p450 PF00067.22 EJP63211.1 - 9.6e-43 146.6 0.0 1.3e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 EJP63212.1 - 7.8e-39 133.5 0.0 1.2e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP63212.1 - 1.1e-06 29.5 0.1 2.3e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IDO PF01231.18 EJP63213.1 - 0.0018 17.2 0.2 0.24 10.1 0.2 3.0 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase PS_Dcarbxylase PF02666.15 EJP63214.1 - 8.4e-39 133.2 0.0 1.3e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EJP63214.1 - 4.4e-35 120.7 0.0 7e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EJP63214.1 - 0.044 13.6 0.0 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like p450 PF00067.22 EJP63215.1 - 1.5e-62 211.9 0.0 1.8e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EJP63216.1 - 3.3e-25 88.7 23.7 3.3e-25 88.7 23.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 EJP63216.1 - 8 6.9 8.3 0.84 10.0 0.3 3.4 4 1 1 5 5 5 0 Phage holin family Hol44, in holin superfamily V PPTA PF01239.22 EJP63217.1 - 1.6e-36 123.0 14.1 1.5e-06 27.7 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_6 PF13174.6 EJP63217.1 - 0.00065 20.2 0.7 0.013 16.1 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP63217.1 - 0.003 17.5 0.6 0.19 11.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP63217.1 - 0.01 16.3 5.2 0.082 13.4 0.0 3.6 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP63217.1 - 0.034 15.0 0.2 0.034 15.0 0.2 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EJP63217.1 - 0.06 13.5 3.1 0.32 11.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EJP63217.1 - 0.42 10.9 5.3 0.16 12.3 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EJP63217.1 - 1.2 10.0 6.3 8.6 7.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 EJP63218.1 - 0.011 15.6 2.6 0.011 15.6 2.6 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_3 PF13878.6 EJP63218.1 - 0.12 12.2 0.2 7.1 6.6 0.0 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-RING_5 PF14634.6 EJP63218.1 - 0.61 10.1 12.0 0.096 12.7 7.0 2.3 2 1 0 2 2 2 0 zinc-RING finger domain CAP_N PF01213.19 EJP63218.1 - 1.4 8.3 6.6 1.9 7.9 6.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-RING_UBOX PF13445.6 EJP63218.1 - 1.7 8.7 6.4 0.32 11.1 1.5 2.4 1 1 1 2 2 2 0 RING-type zinc-finger GHMP_kinases_N PF00288.26 EJP63219.1 - 1.1e-16 60.7 0.0 2.6e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EJP63219.1 - 3.1e-09 37.1 0.0 7.9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EJP63219.1 - 0.0072 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature ABM PF03992.16 EJP63220.1 - 0.012 15.7 0.1 0.04 14.0 0.0 1.9 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase A_amylase_inhib PF01356.19 EJP63220.1 - 0.045 13.7 0.1 0.083 12.9 0.1 1.4 1 0 0 1 1 1 0 Alpha amylase inhibitor Ribosomal_L38e PF01781.18 EJP63221.1 - 4.9e-33 113.0 6.4 5.5e-33 112.9 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Cyclophil_like2 PF18050.1 EJP63221.1 - 0.05 13.6 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin-like family Orn_Arg_deC_N PF02784.16 EJP63222.1 - 9e-83 277.4 0.0 1.2e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EJP63222.1 - 4.9e-18 65.2 0.0 6.6e-18 64.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF3146 PF11344.8 EJP63222.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3146) M16C_assoc PF08367.11 EJP63223.1 - 5.7e-84 281.2 0.1 1.2e-83 280.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EJP63223.1 - 3.9e-30 105.2 0.0 5.9e-21 75.3 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EJP63223.1 - 1.9e-09 37.6 0.2 6.8e-08 32.6 0.0 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Taxilin PF09728.9 EJP63224.1 - 2.8e-73 246.8 61.7 3.5e-73 246.5 61.7 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Glyco_transf_17 PF04724.13 EJP63225.1 - 2.2e-42 145.4 0.0 5.3e-42 144.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 17 Enterotoxin_a PF01375.17 EJP63227.1 - 0.00086 19.0 0.2 0.0047 16.6 0.2 1.9 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain Pertussis_S1 PF02917.14 EJP63227.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Pertussis toxin, subunit 1 Peptidase_M48_N PF16491.5 EJP63228.1 - 8.1e-63 211.6 6.7 8.1e-63 211.6 6.7 1.5 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EJP63228.1 - 1.4e-48 165.3 0.0 2.2e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EJP63228.1 - 2.1e-05 23.9 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.6 EJP63228.1 - 0.047 13.4 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M16_C PF05193.21 EJP63229.1 - 1.9e-16 60.6 0.0 7.6e-14 52.1 0.0 3.3 4 0 0 4 4 4 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EJP63229.1 - 7.5e-08 32.5 0.0 4.9e-06 26.6 0.0 2.6 3 0 0 3 3 2 1 Insulinase (Peptidase family M16) DNA_pol_phi PF04931.13 EJP63229.1 - 0.0036 15.5 15.3 0.0066 14.6 15.3 1.4 1 0 0 1 1 1 1 DNA polymerase phi RQC PF09382.10 EJP63229.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RQC domain M16C_assoc PF08367.11 EJP63229.1 - 0.11 11.6 5.3 0.79 8.8 3.6 2.2 2 0 0 2 2 2 0 Peptidase M16C associated Sigma70_ner PF04546.13 EJP63229.1 - 0.81 9.5 14.9 0.66 9.8 10.0 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2457 PF10446.9 EJP63229.1 - 1.4 8.0 24.8 2 7.4 24.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 EJP63229.1 - 2.2 7.8 12.9 4.6 6.7 12.9 1.6 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EJP63229.1 - 2.4 7.4 21.6 3.5 6.9 21.6 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EJP63229.1 - 6.8 6.7 10.3 13 5.8 10.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 EJP63229.1 - 8.5 5.7 16.1 0.15 11.5 8.3 1.9 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 EJP63229.1 - 9.8 4.3 13.3 14 3.8 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Zw10 PF06248.13 EJP63230.1 - 1.1e-09 37.4 3.0 0.00015 20.5 2.0 2.5 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EJP63230.1 - 0.018 14.8 0.1 0.06 13.1 0.1 2.0 1 1 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal PI-PLC-X PF00388.19 EJP63231.1 - 1.7e-59 199.6 0.0 3.4e-59 198.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EJP63231.1 - 8.9e-43 145.3 0.0 2.3e-42 144.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 EJP63231.1 - 0.0016 18.8 0.0 0.0046 17.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_12 PF16457.5 EJP63231.1 - 0.0029 18.1 0.6 0.017 15.7 0.3 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain DHHC PF01529.20 EJP63232.1 - 2e-38 131.5 10.5 2e-38 131.5 10.5 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase SUIM_assoc PF16619.5 EJP63232.1 - 6.7e-05 22.9 0.0 0.0004 20.4 0.0 2.3 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 FtsX PF02687.21 EJP63232.1 - 1.5 9.4 5.4 3.3 8.2 5.4 1.5 1 0 0 1 1 1 0 FtsX-like permease family Tau95 PF09734.9 EJP63233.1 - 1.7e-38 132.6 0.2 4.2e-38 131.3 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EJP63233.1 - 8.1e-37 126.3 0.0 1.9e-36 125.0 0.0 1.7 1 0 0 1 1 1 1 Tau95 Triple barrel domain zf-C2H2 PF00096.26 EJP63233.1 - 2.2e-05 24.6 0.2 0.074 13.5 0.1 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP63233.1 - 0.0003 21.4 1.1 2.3 9.3 0.1 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EJP63233.1 - 0.036 14.4 0.4 0.26 11.6 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 EJP63233.1 - 0.067 13.7 4.7 0.25 11.8 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double domain B56 PF01603.20 EJP63234.1 - 6e-193 641.5 2.0 7e-193 641.2 2.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EJP63234.1 - 5.2e-05 23.2 0.8 0.3 11.0 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal CTD_bind PF04818.13 EJP63235.1 - 6.7e-11 42.9 0.1 1.6e-10 41.6 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF4748 PF15932.5 EJP63236.1 - 3.7e-27 93.8 0.3 5.3e-27 93.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Barttin PF15462.6 EJP63236.1 - 0.044 13.6 1.4 0.05 13.4 1.4 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Exo_endo_phos PF03372.23 EJP63237.1 - 1.3e-10 41.2 0.1 2.5e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SKG6 PF08693.10 EJP63238.1 - 0.088 12.2 1.2 0.22 11.0 1.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 EJP63238.1 - 0.14 12.1 0.4 0.26 11.2 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain adh_short PF00106.25 EJP63239.1 - 3.7e-31 108.1 0.0 1.2e-23 83.6 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EJP63239.1 - 2.1e-24 86.4 0.0 2.2e-18 66.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP63239.1 - 1e-08 35.3 0.1 1.6e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF2804 PF10974.8 EJP63239.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) CRAL_TRIO PF00650.20 EJP63240.1 - 2e-39 134.9 0.0 2.7e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJP63240.1 - 2.9e-14 53.0 0.4 6.7e-14 51.8 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Fasciclin PF02469.22 EJP63241.1 - 1.9e-35 121.9 0.1 3.8e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain CN_hydrolase PF00795.22 EJP63242.1 - 2.6e-41 141.7 0.0 3e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_3 PF07859.13 EJP63243.1 - 1.3e-22 80.7 0.9 2e-22 80.1 0.9 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP63243.1 - 1.8e-11 43.5 0.0 3.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Cbl_N2 PF02761.14 EJP63243.1 - 0.019 15.7 0.1 0.076 13.7 0.0 2.0 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Methyltransf_3 PF01596.17 EJP63244.1 - 2.6e-24 85.6 0.0 3.3e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EJP63244.1 - 2e-09 38.4 0.0 4.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP63244.1 - 1.3e-05 25.8 0.0 2.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EJP63244.1 - 3.9e-05 23.3 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 EJP63244.1 - 4.1e-05 24.2 0.0 6.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EJP63244.1 - 0.00041 20.0 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 EJP63244.1 - 0.0033 17.2 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EJP63244.1 - 0.051 13.4 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EJP63244.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Peptidase_M28 PF04389.17 EJP63245.1 - 4.9e-44 150.4 0.0 8.9e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EJP63245.1 - 2.2e-09 37.2 0.0 8.2e-09 35.4 0.0 2.0 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EJP63245.1 - 2.1e-05 24.3 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HATPase_c PF02518.26 EJP63246.1 - 1.1e-27 96.8 0.6 3.7e-26 91.8 0.6 2.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EJP63246.1 - 5.1e-27 94.3 0.2 9e-27 93.5 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EJP63246.1 - 7.4e-10 38.7 0.0 2.4e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 EJP63246.1 - 0.036 13.9 1.2 0.09 12.5 1.2 1.6 1 1 0 1 1 1 0 Cache domain HAMP PF00672.25 EJP63246.1 - 0.15 12.5 0.0 23 5.4 0.0 2.5 2 0 0 2 2 2 0 HAMP domain DUF948 PF06103.11 EJP63246.1 - 0.18 12.1 5.0 4.3 7.6 0.1 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Reprolysin_5 PF13688.6 EJP63247.1 - 1.9e-05 24.9 0.9 5.7e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EJP63247.1 - 5.7e-05 23.6 0.0 0.00017 22.1 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 EJP63247.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M57 PF12388.8 EJP63247.1 - 0.0052 16.4 0.2 0.0052 16.4 0.2 1.7 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 EJP63247.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 EJP63247.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EJP63247.1 - 0.028 14.3 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like LMP PF04778.12 EJP63247.1 - 0.36 10.7 7.8 0.75 9.7 7.8 1.5 1 0 0 1 1 1 0 LMP repeated region CVNH PF08881.10 EJP63248.1 - 1.1e-26 93.5 0.7 1.3e-26 93.3 0.7 1.1 1 0 0 1 1 1 1 CVNH domain DUF916 PF06030.12 EJP63248.1 - 0.22 11.6 0.0 1.2 9.2 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF916) 2OG-FeII_Oxy_3 PF13640.6 EJP63249.1 - 1.9e-09 38.3 0.0 3.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Laminin_G_3 PF13385.6 EJP63250.1 - 0.021 15.0 0.6 0.039 14.1 0.6 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily eIF-3_zeta PF05091.12 EJP63251.1 - 0.95 8.4 11.9 1.4 7.8 11.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NACHT PF05729.12 EJP63254.1 - 0.0071 16.3 0.1 0.0092 15.9 0.1 1.2 1 0 0 1 1 1 1 NACHT domain CTXphi_pIII-N1 PF16710.5 EJP63254.1 - 0.077 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Mito_carr PF00153.27 EJP63255.1 - 4.5e-44 148.3 1.9 8.9e-17 60.8 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Bromodomain PF00439.25 EJP63256.1 - 1.4e-39 134.0 1.3 1.7e-19 69.7 0.4 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EJP63256.1 - 1.7e-19 69.9 0.3 3.7e-19 68.8 0.3 1.6 1 0 0 1 1 1 1 BAH domain RTP PF02334.16 EJP63256.1 - 0.035 14.7 0.8 0.073 13.7 0.8 1.4 1 0 0 1 1 1 0 Replication terminator protein CNDH2_C PF16858.5 EJP63256.1 - 6.8 6.5 15.4 1.1 9.1 3.4 2.7 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 EJP63256.1 - 7.5 4.7 19.6 4.2 5.5 17.5 1.5 1 1 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 EJP63256.1 - 8.3 6.6 24.0 2 8.6 11.9 2.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 OTU PF02338.19 EJP63257.1 - 1.7e-07 31.8 0.0 2.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease EI24 PF07264.11 EJP63258.1 - 3.8e-15 56.6 9.7 2.5e-07 31.1 2.2 2.2 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 EJP63259.1 - 1.5e-30 106.0 0.0 3.6e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Cofilin_ADF PF00241.20 EJP63261.1 - 1.4e-18 66.8 0.0 1.6e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3435 PF11917.8 EJP63261.1 - 0.13 11.2 0.0 7.8 5.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) ParA PF10609.9 EJP63262.1 - 1.1e-96 323.0 0.0 1.3e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EJP63262.1 - 2.4e-07 30.9 0.0 5.7e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EJP63262.1 - 2.3e-05 24.4 0.0 0.00024 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EJP63262.1 - 0.00026 20.3 0.4 0.00084 18.6 0.2 1.9 1 1 1 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 EJP63262.1 - 0.00068 19.2 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 EJP63262.1 - 0.0084 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EJP63262.1 - 0.0093 15.9 0.0 0.021 14.7 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase AAA_26 PF13500.6 EJP63262.1 - 0.012 15.5 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain MipZ PF09140.11 EJP63262.1 - 0.023 14.0 0.0 0.054 12.8 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ TsaE PF02367.17 EJP63262.1 - 0.031 14.3 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLP1_P PF16575.5 EJP63262.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 EJP63262.1 - 0.067 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 EJP63262.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 EJP63262.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EJP63262.1 - 0.091 13.1 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 EJP63262.1 - 0.093 13.1 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EJP63262.1 - 0.21 11.5 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain HEAT_2 PF13646.6 EJP63263.1 - 1.6e-26 92.5 4.3 2.7e-13 50.1 0.1 3.2 3 1 1 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 EJP63263.1 - 4.5e-21 73.3 4.3 0.00046 20.6 0.1 6.0 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EJP63263.1 - 4.1e-10 39.0 1.7 0.017 15.3 0.0 5.3 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EJP63263.1 - 1.1e-06 29.0 9.4 0.41 11.2 0.0 5.6 3 2 3 6 6 6 3 HEAT-like repeat Arm PF00514.23 EJP63263.1 - 0.00051 20.0 0.3 1.2 9.3 0.1 2.9 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat RuvA_C PF07499.13 EJP63263.1 - 1.6 9.2 4.7 16 6.0 0.0 3.3 4 0 0 4 4 4 0 RuvA, C-terminal domain TFIIS_C PF01096.18 EJP63264.1 - 3.2e-15 55.7 2.0 3.2e-15 55.7 2.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EJP63264.1 - 8.6e-05 22.3 3.7 8.6e-05 22.3 3.7 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.6 EJP63264.1 - 0.00037 20.1 14.8 0.32 10.8 1.8 3.7 4 0 0 4 4 4 3 zinc-ribbon domain C1_1 PF00130.22 EJP63264.1 - 0.016 15.1 1.3 0.016 15.1 1.3 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lar_restr_allev PF14354.6 EJP63264.1 - 0.016 15.5 10.5 0.19 12.1 0.6 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 EJP63264.1 - 0.027 14.5 4.6 1.7 8.7 0.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 EJP63264.1 - 0.027 14.6 6.8 0.47 10.6 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_7 PF02591.15 EJP63264.1 - 0.038 14.2 5.2 5.1 7.4 0.1 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain DZR PF12773.7 EJP63264.1 - 0.045 13.8 10.4 0.18 11.9 2.1 2.4 2 1 1 3 3 3 0 Double zinc ribbon HypA PF01155.19 EJP63264.1 - 0.081 13.0 8.3 0.95 9.5 1.3 2.5 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mu-like_Com PF10122.9 EJP63264.1 - 0.34 10.4 5.0 0.77 9.3 1.3 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-ISL3 PF14690.6 EJP63264.1 - 0.84 10.4 5.8 5.3 7.8 0.2 2.9 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-RING_4 PF14570.6 EJP63264.1 - 1.3 8.9 11.5 5.8 6.8 0.1 3.4 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain eIF-5_eIF-2B PF01873.17 EJP63264.1 - 1.4 8.8 7.3 0.78 9.6 1.4 2.3 2 1 0 2 2 2 0 Domain found in IF2B/IF5 zf-IS66 PF13005.7 EJP63264.1 - 1.5 9.3 10.9 8.9 6.8 0.1 3.4 2 1 1 3 3 3 0 zinc-finger binding domain of transposase IS66 zf_UBZ PF18439.1 EJP63264.1 - 1.7 8.3 7.2 12 5.6 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger NOB1_Zn_bind PF08772.11 EJP63264.1 - 2.1 8.6 11.1 9.8e+02 0.0 10.6 3.0 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF1922 PF09082.10 EJP63264.1 - 7.6 6.9 8.5 2.7 8.4 0.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1922) Nipped-B_C PF12830.7 EJP63265.1 - 1e-49 169.1 2.8 7.1e-48 163.1 1.8 2.9 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EJP63265.1 - 1.2e-08 35.1 0.6 8.7e-08 32.3 0.6 2.7 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EJP63265.1 - 4.9e-05 23.2 2.5 0.18 12.1 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EJP63265.1 - 0.00083 19.4 0.0 0.028 14.5 0.0 3.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 PSY3 PF16836.5 EJP63265.1 - 0.077 12.5 0.1 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 Shu complex component Psy3, DNA-binding description IlvN PF07991.12 EJP63265.1 - 0.13 11.9 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ArdA PF07275.11 EJP63265.1 - 0.75 10.4 2.3 1 9.9 0.2 2.4 2 1 0 2 2 2 0 Antirestriction protein (ArdA) Na_Ca_ex PF01699.24 EJP63266.1 - 1e-46 158.7 34.7 1.3e-23 83.6 13.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YwcE PF17368.2 EJP63266.1 - 0.85 10.3 0.1 0.85 10.3 0.1 3.7 4 0 0 4 4 4 0 Spore morphogenesis and germination YwcE NUDIX PF00293.28 EJP63269.1 - 1e-21 77.3 0.2 1.2e-21 77.1 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EJP63269.1 - 0.00014 21.8 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RGS PF00615.19 EJP63270.1 - 0.00033 20.9 0.0 0.00082 19.6 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain Ribosomal_S30 PF04758.14 EJP63271.1 - 1.1e-28 99.2 6.0 1.2e-28 99.0 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 RRM_1 PF00076.22 EJP63272.1 - 2.8e-12 46.2 0.1 7e-11 41.8 0.1 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YCII PF03795.14 EJP63272.1 - 0.022 15.1 0.0 0.044 14.2 0.0 1.4 1 1 0 1 1 1 0 YCII-related domain WD40 PF00400.32 EJP63273.1 - 5.9e-05 23.8 12.2 0.0014 19.4 0.8 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 EJP63273.1 - 0.23 11.7 3.8 0.55 10.5 3.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family PHD PF00628.29 EJP63273.1 - 3.9 7.5 10.8 0.69 9.9 0.2 3.1 4 0 0 4 4 4 0 PHD-finger DUF4379 PF14311.6 EJP63273.1 - 6.2 7.3 10.5 4.1 7.9 0.5 3.1 2 0 0 2 2 2 0 Probable Zinc-ribbon domain ERO1 PF04137.15 EJP63274.1 - 7.7e-129 429.9 0.0 1e-128 429.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Atg14 PF10186.9 EJP63274.1 - 4.7e-07 29.2 0.5 5.8e-06 25.6 0.5 2.3 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EJP63274.1 - 0.00041 19.4 0.0 0.0066 15.4 0.0 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting 38 FliT PF05400.13 EJP63274.1 - 7.3 7.5 11.1 30 5.5 2.9 3.4 2 0 0 2 2 2 0 Flagellar protein FliT CKS PF01111.19 EJP63275.1 - 1.1e-34 118.4 1.2 1.6e-34 118.0 1.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit HVSL PF09749.9 EJP63276.1 - 7.9e-80 267.7 0.0 9.4e-80 267.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3245 PF11595.8 EJP63276.1 - 0.021 15.3 0.9 0.17 12.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Pinin_SDK_N PF04697.13 EJP63276.1 - 0.047 14.3 0.5 0.16 12.6 0.0 1.9 2 0 0 2 2 2 0 pinin/SDK conserved region Pal1 PF08316.11 EJP63277.1 - 5.6e-08 33.6 0.2 1.3e-07 32.4 0.2 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein Cu-oxidase_3 PF07732.15 EJP63278.1 - 8.2e-39 132.3 2.7 3.7e-38 130.2 2.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP63278.1 - 5.2e-37 126.6 8.5 2.7e-35 121.1 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EJP63278.1 - 4.9e-34 117.7 0.6 3.2e-33 115.1 0.0 2.6 3 1 1 4 4 4 1 Multicopper oxidase BCNT PF07572.12 EJP63278.1 - 0.21 11.7 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 Bucentaur or craniofacial development Ank_2 PF12796.7 EJP63279.1 - 4.8e-24 84.8 0.1 3.2e-13 50.1 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP63279.1 - 6.1e-19 68.1 0.2 6.1e-06 26.7 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EJP63279.1 - 1.5e-16 60.0 2.3 0.0047 17.3 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EJP63279.1 - 1e-15 56.2 0.2 0.064 13.8 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EJP63279.1 - 4.3e-13 49.2 3.2 0.0013 18.9 0.0 5.7 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 EJP63279.1 - 0.065 13.0 0.1 11 5.7 0.0 2.8 1 1 1 3 3 3 0 Shigella flexneri OspC protein Abhydrolase_4 PF08386.10 EJP63280.1 - 7.7e-19 67.7 0.0 4.2e-18 65.4 0.0 2.2 2 1 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 EJP63280.1 - 1.7e-15 57.3 0.0 4.9e-05 23.1 0.0 3.4 3 0 0 3 3 3 3 alpha/beta hydrolase fold LCE PF14672.6 EJP63281.1 - 0.11 13.1 47.7 0.46 11.1 12.5 4.4 2 1 1 3 3 3 0 Late cornified envelope LIN37 PF15306.6 EJP63281.1 - 0.25 11.5 4.8 0.35 11.1 4.8 1.2 1 0 0 1 1 1 0 LIN37 APH PF01636.23 EJP63283.1 - 1.2e-06 28.7 0.5 2.5e-06 27.6 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4135 PF13575.6 EJP63283.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PAD PF03068.15 EJP63284.1 - 2.3e-29 102.6 0.0 2.5e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) His_Phos_1 PF00300.22 EJP63286.1 - 4.7e-36 124.3 0.4 2.7e-18 66.4 0.5 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) TUDOR PF00567.24 EJP63286.1 - 0.13 12.3 0.0 20 5.2 0.0 2.2 2 0 0 2 2 2 0 Tudor domain Methyltransf_23 PF13489.6 EJP63287.1 - 1.2e-11 44.7 0.0 1.6e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP63287.1 - 2.6e-09 36.8 0.0 6e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EJP63287.1 - 6.9e-08 33.1 0.0 1.6e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP63287.1 - 2.1e-06 28.3 0.1 6.6e-06 26.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP63287.1 - 8.7e-06 25.6 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP63287.1 - 2.5e-05 24.9 0.0 4.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP63287.1 - 0.0089 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EJP63287.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Zn_clus PF00172.18 EJP63289.1 - 6.1e-08 32.7 8.0 8.9e-08 32.1 8.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.31 EJP63290.1 - 5.2e-17 62.1 0.1 8.7e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain GAT PF03127.14 EJP63291.1 - 3.9e-18 65.5 0.3 1.3e-17 63.9 0.3 1.9 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 EJP63291.1 - 4.8e-05 23.2 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 VHS domain CBM_5_12 PF02839.14 EJP63291.1 - 0.16 12.6 1.7 0.26 11.9 0.0 2.4 2 1 0 2 2 2 0 Carbohydrate binding domain Serglycin PF04360.12 EJP63291.1 - 0.92 9.5 4.0 0.52 10.2 1.2 1.9 2 0 0 2 2 2 0 Serglycin UBA_4 PF14555.6 EJP63292.1 - 7.2e-11 41.7 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EJP63292.1 - 1.4e-06 28.4 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain SUB1_ProdP9 PF18213.1 EJP63292.1 - 0.031 14.1 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Pox_F11 PF04943.12 EJP63292.1 - 0.21 10.7 1.0 0.35 9.9 1.0 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Acetyltransf_1 PF00583.25 EJP63293.1 - 4.7e-11 42.9 0.0 6.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP63293.1 - 1.3e-08 35.2 0.0 2.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP63293.1 - 7.4e-07 29.1 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP63293.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EJP63293.1 - 0.0025 17.9 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EJP63293.1 - 0.035 14.1 0.1 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 EJP63293.1 - 0.057 12.9 0.1 0.28 10.6 0.1 1.9 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_8 PF13523.6 EJP63293.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_2 PF02230.16 EJP63294.1 - 5.6e-23 81.9 0.0 2.3e-09 37.4 0.0 3.0 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EJP63294.1 - 2.1e-08 35.0 0.8 2.8e-08 34.7 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EJP63294.1 - 1.1e-05 25.0 0.0 4.2e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EJP63294.1 - 0.0021 17.4 0.2 3.5 6.8 0.0 3.2 3 1 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP63294.1 - 0.0046 16.6 0.0 0.1 12.2 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 EJP63294.1 - 0.0065 16.2 0.0 0.53 9.9 0.0 2.5 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 EJP63294.1 - 0.042 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EJP63294.1 - 0.077 12.8 0.1 0.57 10.0 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold HTH_Tnp_Tc5 PF03221.16 EJP63295.1 - 9.2e-11 41.6 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EJP63295.1 - 5.6e-10 38.8 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 EJP63295.1 - 0.016 15.0 0.1 0.042 13.7 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain CarbpepA_inh PF02977.15 EJP63297.1 - 0.41 10.5 1.6 0.51 10.2 0.3 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor FMO-like PF00743.19 EJP63298.1 - 1.2e-59 202.2 0.0 6.3e-59 199.8 0.0 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP63298.1 - 3.1e-11 43.1 0.0 2e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP63298.1 - 5.7e-11 42.2 0.0 6.1e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP63298.1 - 2.6e-08 33.4 0.0 3.1e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EJP63298.1 - 3.9e-07 30.2 0.8 0.0011 19.0 0.2 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EJP63298.1 - 3.5e-05 23.6 0.2 0.13 11.8 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP63298.1 - 0.00029 21.0 0.1 0.0011 19.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EJP63298.1 - 0.0053 16.1 0.0 0.51 9.6 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 EJP63298.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_M17_N PF02789.17 EJP63298.1 - 0.01 15.7 0.6 0.054 13.4 0.0 2.1 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain HI0933_like PF03486.14 EJP63298.1 - 0.016 13.9 0.3 0.48 9.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 EJP63298.1 - 0.021 15.3 0.0 1 9.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EJP63298.1 - 0.022 14.8 0.1 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 EJP63298.1 - 0.031 13.8 0.0 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 EJP63298.1 - 0.06 13.5 0.4 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EJP63298.1 - 0.19 11.1 0.1 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 EJP63298.1 - 0.19 11.0 0.2 0.97 8.7 0.2 1.9 2 0 0 2 2 2 0 ThiF family NLPC_P60 PF00877.19 EJP63299.1 - 5.8e-19 68.1 0.2 7.8e-19 67.7 0.2 1.1 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.13 EJP63299.1 - 8.1e-05 22.5 0.2 0.00015 21.7 0.1 1.4 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase DUF1175 PF06672.11 EJP63299.1 - 0.0051 16.5 0.0 0.1 12.2 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1175) CHAP PF05257.16 EJP63299.1 - 0.0066 17.0 1.0 0.0094 16.5 1.0 1.4 1 0 0 1 1 1 1 CHAP domain Wzy_C_2 PF11846.8 EJP63300.1 - 0.024 14.5 0.0 0.028 14.3 0.0 1.0 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal UCH PF00443.29 EJP63301.1 - 1.3e-48 165.7 0.0 1.7e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJP63301.1 - 8e-13 48.7 2.3 2.7e-12 46.9 2.3 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EJP63301.1 - 1.8e-11 43.6 1.6 2.8e-11 43.0 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin family ARPC4 PF05856.12 EJP63302.1 - 1.2e-78 262.5 3.4 1.4e-78 262.3 3.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Glyco_transf_25 PF01755.17 EJP63304.1 - 4.7e-11 42.9 0.0 3.4e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF3318 PF11780.8 EJP63306.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) SET PF00856.28 EJP63307.1 - 1.4e-14 54.8 1.5 6.7e-14 52.6 1.5 2.2 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EJP63307.1 - 4.3e-07 29.8 7.8 1.3e-06 28.3 7.8 1.8 1 0 0 1 1 1 1 AWS domain CRAL_TRIO PF00650.20 EJP63308.1 - 1.2e-14 54.3 0.0 1.8e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJP63308.1 - 3.6e-07 30.2 0.0 7.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CT47 PF15623.6 EJP63308.1 - 5.2 6.8 17.1 11 5.8 17.1 1.5 1 0 0 1 1 1 0 Cancer/testis gene family 47 HSDR_N_2 PF13588.6 EJP63309.1 - 0.0029 17.6 0.2 0.2 11.6 0.0 2.4 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) VioE PF18234.1 EJP63309.1 - 0.17 12.0 0.5 0.47 10.6 0.1 1.8 2 0 0 2 2 2 0 Violacein biosynthetic enzyme VioE DHHC PF01529.20 EJP63310.1 - 2.1e-28 99.1 0.1 2.7e-28 98.7 0.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase FXR_C1 PF16096.5 EJP63310.1 - 0.3 11.3 3.9 0.91 9.8 3.9 1.8 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 TMEM51 PF15345.6 EJP63311.1 - 0.2 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 SUIM_assoc PF16619.5 EJP63311.1 - 1.2 9.3 6.3 4.4 7.4 6.8 1.7 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3328 PF11807.8 EJP63312.1 - 3.4e-41 141.4 1.1 4.3e-41 141.1 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_cc PF11790.8 EJP63313.1 - 1.7e-50 171.8 0.8 1.9e-50 171.7 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core IMS PF00817.20 EJP63314.1 - 5.4e-38 130.3 0.0 1.5e-37 128.9 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EJP63314.1 - 4.7e-11 43.4 0.0 1.2e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EJP63314.1 - 3e-10 39.5 1.5 6.1e-10 38.5 1.5 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Pkip-1 PF06878.11 EJP63314.1 - 0.022 14.8 0.6 0.038 14.1 0.6 1.3 1 0 0 1 1 1 0 Pkip-1 protein IMS_HHH PF11798.8 EJP63314.1 - 0.026 14.8 0.1 0.086 13.2 0.1 1.9 1 0 0 1 1 1 0 IMS family HHH motif IBN_N PF03810.19 EJP63317.1 - 3e-16 59.1 1.6 9.2e-14 51.1 0.0 3.5 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.10 EJP63317.1 - 5.9e-07 28.6 0.0 1.7e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 EJP63317.1 - 0.00021 21.4 0.6 0.0051 16.9 0.1 3.2 3 0 0 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.15 EJP63317.1 - 0.0016 17.1 0.1 0.029 12.8 0.0 2.8 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus RIX1 PF08167.12 EJP63317.1 - 0.012 15.3 0.0 2.6 7.8 0.0 3.6 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 EJP63317.1 - 0.015 15.6 4.1 2 8.9 0.4 3.9 2 1 1 3 3 3 0 HEAT repeats MOR2-PAG1_C PF14225.6 EJP63317.1 - 0.034 14.0 1.2 0.091 12.6 0.2 2.2 3 0 0 3 3 3 0 Cell morphogenesis C-terminal GRIP PF01465.20 EJP63317.1 - 0.036 14.0 0.1 0.6 10.1 0.1 3.0 2 0 0 2 2 2 0 GRIP domain PEX11 PF05648.14 EJP63318.1 - 1.8e-23 83.2 2.1 4.7e-23 81.8 2.1 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Serpentine_r_xa PF03383.15 EJP63318.1 - 0.012 15.6 0.7 0.02 14.9 0.7 1.3 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Caskin-Pro-rich PF16907.5 EJP63318.1 - 1.5 9.4 5.7 4.2 8.0 0.8 2.3 2 0 0 2 2 2 0 Proline rich region of Caskin proteins ISN1 PF06437.11 EJP63319.1 - 5.7e-196 651.3 0.0 6.4e-196 651.1 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase MFS_1 PF07690.16 EJP63321.1 - 1.4e-08 34.1 17.8 5.1e-08 32.2 17.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP63321.1 - 1.4e-06 27.5 0.8 1.4e-06 27.5 0.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Pkinase PF00069.25 EJP63322.1 - 2.8e-08 33.5 0.0 4.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EJP63322.1 - 3.3e-06 27.2 0.1 4.3e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP63322.1 - 0.00066 19.3 0.0 0.00095 18.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EJP63322.1 - 0.00098 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EJP63322.1 - 0.02 13.7 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EJP63322.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 EJP63322.1 - 0.18 11.0 0.0 0.53 9.5 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EJP63322.1 - 0.23 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RCR PF12273.8 EJP63323.1 - 2.1e-05 25.2 0.3 2.8e-05 24.7 0.3 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Vpu PF00558.19 EJP63323.1 - 0.064 13.0 0.2 0.081 12.7 0.2 1.1 1 0 0 1 1 1 0 Vpu protein CAP_N PF01213.19 EJP63323.1 - 3.9 6.9 5.0 4.2 6.8 5.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NACHT_N PF17100.5 EJP63324.1 - 1.9e-42 145.6 0.0 3.6e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 EJP63324.1 - 2.9e-32 110.2 20.4 9.6e-11 42.1 0.3 9.1 9 0 0 9 9 9 5 WD domain, G-beta repeat NACHT PF05729.12 EJP63324.1 - 4.7e-21 75.4 0.2 1.2e-20 74.0 0.2 1.7 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 EJP63324.1 - 1e-12 48.1 0.1 0.00094 19.4 0.0 5.2 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EJP63324.1 - 0.00097 19.0 3.4 0.074 13.0 0.1 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EJP63324.1 - 0.0012 17.6 4.5 0.1 11.2 0.1 3.7 3 1 0 4 4 4 2 Nucleoporin Nup120/160 AAA_19 PF13245.6 EJP63324.1 - 0.19 12.1 0.0 1.6 9.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain Autophagy_N PF03986.13 EJP63325.1 - 9.7e-45 151.9 0.1 2.1e-44 150.8 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EJP63325.1 - 5.4e-16 57.8 0.6 1.1e-15 56.8 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EJP63325.1 - 6e-16 58.8 0.1 1.1e-15 57.9 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain PBP1_TM PF14812.6 EJP63325.1 - 0.14 12.5 3.6 0.15 12.4 1.8 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF241 PF03087.14 EJP63326.1 - 0.093 12.5 0.3 0.15 11.9 0.3 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Stathmin PF00836.19 EJP63326.1 - 3.9 7.5 8.6 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Stathmin family APH PF01636.23 EJP63327.1 - 3.2e-12 46.9 0.0 1.5e-11 44.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP63327.1 - 4e-07 29.8 0.1 6.5e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EJP63328.1 - 1.4e-50 172.1 0.0 1.9e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP63328.1 - 2.1e-26 92.8 0.7 2.7e-25 89.1 0.7 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP63328.1 - 0.021 13.6 0.0 0.041 12.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EJP63328.1 - 0.042 13.2 0.8 0.18 11.1 0.2 2.3 2 1 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EJP63328.1 - 0.055 13.1 0.2 0.92 9.1 0.1 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-CCCH PF00642.24 EJP63330.1 - 1.9e-08 34.0 2.8 3.6e-08 33.1 2.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EJP63330.1 - 2.3e-07 30.5 4.2 4.4e-07 29.7 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJP63330.1 - 1.3e-06 28.1 6.7 2.6e-06 27.2 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP63330.1 - 1.8e-06 27.7 6.1 3.4e-06 26.8 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP63330.1 - 8.6e-06 25.6 6.5 1.6e-05 24.8 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EJP63330.1 - 3.2e-05 23.9 6.6 6.3e-05 22.9 6.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 EJP63330.1 - 7.8e-05 22.6 6.9 0.00014 21.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 EJP63330.1 - 0.00018 21.7 5.8 0.00035 20.8 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 EJP63330.1 - 0.00032 20.8 3.1 0.00032 20.8 3.1 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 EJP63330.1 - 0.00045 19.9 3.1 0.00079 19.2 3.1 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 EJP63330.1 - 0.016 15.0 4.2 0.03 14.2 4.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EJP63330.1 - 0.048 13.8 7.0 0.12 12.6 7.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Harakiri PF15196.6 EJP63330.1 - 0.066 13.7 2.0 0.12 12.9 0.2 2.2 2 0 0 2 2 2 0 Activator of apoptosis harakiri Mcp5_PH PF12814.7 EJP63331.1 - 1.4e-44 151.1 0.0 2.9e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EJP63331.1 - 2.3e-05 24.8 0.0 5.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Dynein_IC2 PF11540.8 EJP63331.1 - 0.037 14.0 7.0 35 4.4 0.3 4.7 4 0 0 4 4 4 0 Cytoplasmic dynein 1 intermediate chain 2 PIN_9 PF18477.1 EJP63331.1 - 0.24 11.7 2.6 0.7 10.2 2.6 1.8 1 0 0 1 1 1 0 PIN like domain kleA_kleC PF17383.2 EJP63331.1 - 1.6 9.1 9.9 10 6.5 1.1 3.6 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A APG6_N PF17675.1 EJP63331.1 - 4.4 7.8 47.4 1.3 9.6 5.9 4.6 3 1 1 4 4 4 0 Apg6 coiled-coil region MMM1 PF10296.9 EJP63332.1 - 0.00039 19.6 4.1 0.0026 16.9 0.0 2.7 2 1 0 3 3 3 2 Maintenance of mitochondrial morphology protein 1 DNA_pol_B PF00136.21 EJP63333.1 - 2.6e-101 339.6 0.0 3.8e-101 339.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EJP63333.1 - 3.1e-23 82.5 0.0 8.8e-12 44.8 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EJP63333.1 - 3.2e-16 59.5 0.6 9.3e-16 58.1 0.6 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.8 EJP63334.1 - 1.1e-73 248.3 20.3 1.1e-73 248.3 20.3 3.2 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EJP63334.1 - 0.029 14.1 0.5 0.052 13.3 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EJP63334.1 - 0.11 12.7 2.7 0.21 11.7 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 EJP63335.1 - 2.3e-12 46.4 0.9 2.3e-12 46.4 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EJP63335.1 - 8.4e-06 26.6 0.0 1.6e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 EJP63336.1 - 3.1e-46 155.3 4.3 4.4e-46 154.9 3.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e DUF2267 PF10025.9 EJP63336.1 - 0.097 13.0 0.2 0.14 12.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF5486 PF17588.2 EJP63336.1 - 0.13 12.1 1.0 0.37 10.7 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Ank_2 PF12796.7 EJP63337.1 - 7.1e-78 257.3 16.4 1.2e-15 57.9 0.0 14.2 9 4 5 15 15 15 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP63337.1 - 2.8e-61 203.2 38.3 0.00035 21.1 0.0 23.1 15 5 9 24 24 24 15 Ankyrin repeats (many copies) Ank PF00023.30 EJP63337.1 - 6.6e-51 168.6 37.7 0.002 18.5 0.0 22.8 23 1 0 23 23 23 12 Ankyrin repeat Ank_3 PF13606.6 EJP63337.1 - 3.8e-42 137.4 33.5 0.00087 19.6 0.0 25.2 28 1 0 28 28 28 10 Ankyrin repeat Ank_5 PF13857.6 EJP63337.1 - 1.6e-39 133.4 43.5 0.00012 22.3 0.0 20.3 21 2 3 24 24 24 8 Ankyrin repeats (many copies) NACHT PF05729.12 EJP63337.1 - 1.7e-08 34.6 0.0 5.1e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EJP63337.1 - 0.0016 18.9 0.9 0.013 15.9 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 EJP63337.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EJP63337.1 - 0.088 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ANTH PF07651.16 EJP63338.1 - 9.9e-80 267.5 0.0 9.9e-80 267.5 0.0 2.6 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EJP63338.1 - 4.2e-55 186.2 11.2 4.2e-55 186.2 11.2 6.4 4 2 4 8 8 8 2 I/LWEQ domain Surfac_D-trimer PF09006.11 EJP63338.1 - 0.71 9.8 4.0 0.43 10.5 0.5 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation TcdB_N PF12918.7 EJP63338.1 - 7.1 7.0 9.2 1.1 9.6 1.3 3.5 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain MATalpha_HMGbox PF04769.12 EJP63339.1 - 1.5e-54 184.4 0.0 2.5e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Exo_endo_phos PF03372.23 EJP63340.1 - 4.4e-14 52.6 0.1 7e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EJP63340.1 - 0.027 14.3 0.0 2.3 8.1 0.0 2.4 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase zf-GRF PF06839.12 EJP63340.1 - 0.13 12.4 2.7 2.6 8.2 0.1 2.7 2 0 0 2 2 2 0 GRF zinc finger COX6A PF02046.15 EJP63341.1 - 1e-51 174.1 5.1 1.3e-51 173.8 5.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ESSS PF10183.9 EJP63341.1 - 0.00063 19.9 0.5 0.00095 19.3 0.5 1.4 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2933 PF11666.8 EJP63341.1 - 0.031 14.3 0.3 0.05 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) ANAPC5 PF12862.7 EJP63342.1 - 1.2e-31 108.6 3.1 1.2e-31 108.6 3.1 3.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 EJP63342.1 - 0.00064 20.3 8.3 0.056 14.3 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP63342.1 - 0.0034 17.3 4.1 0.07 13.2 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP63342.1 - 0.012 15.4 6.3 0.48 10.3 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJP63342.1 - 0.015 15.4 0.1 0.4 11.0 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EJP63342.1 - 0.055 13.8 0.2 0.055 13.8 0.2 5.3 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EJP63342.1 - 0.14 11.8 0.4 0.69 9.7 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_19 PF14559.6 EJP63342.1 - 0.16 12.5 0.0 0.16 12.5 0.0 5.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 EJP63342.1 - 0.78 10.4 12.2 4.9 7.9 0.8 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat CIA30 PF08547.12 EJP63343.1 - 1.6e-43 148.5 0.0 3.1e-43 147.5 0.0 1.5 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Tim44 PF04280.15 EJP63344.1 - 5.8e-06 26.5 1.0 7e-05 23.0 0.2 2.6 2 1 0 2 2 2 1 Tim44-like domain DUF2922 PF11148.8 EJP63344.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) SSF PF00474.17 EJP63345.1 - 1.4e-09 37.3 28.7 3.4e-09 36.1 28.7 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.22 EJP63346.1 - 5e-23 80.7 0.1 1.5e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EOS1 PF12326.8 EJP63347.1 - 1.4e-16 60.9 3.2 1.4e-16 60.9 3.2 2.5 2 1 1 3 3 3 2 N-glycosylation protein SUI1 PF01253.22 EJP63348.1 - 6.2e-28 97.2 3.6 8e-28 96.8 3.6 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Peptidase_S28 PF05577.12 EJP63349.1 - 5.2e-39 134.2 0.3 7.2e-30 104.1 0.2 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 DAO PF01266.24 EJP63350.1 - 5.5e-32 111.7 1.9 1.3e-29 103.9 1.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP63350.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP63350.1 - 0.016 14.5 0.1 0.031 13.5 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP63350.1 - 0.028 14.4 1.6 0.19 11.7 0.3 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EJP63350.1 - 0.044 14.0 0.4 0.13 12.5 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_18 PF00704.28 EJP63351.1 - 4.9e-18 65.9 0.2 1.3e-17 64.5 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 NifT PF06988.11 EJP63351.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 NifT/FixU protein DUF1581 PF07619.11 EJP63351.1 - 0.15 12.2 0.1 0.42 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) MAP65_ASE1 PF03999.12 EJP63351.1 - 5.5 5.6 5.8 8.9 4.9 5.8 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HALZ PF02183.18 EJP63352.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3439 PF11921.8 EJP63352.1 - 0.25 11.3 9.1 0.4 10.6 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EJP63352.1 - 1.2 7.0 4.5 1.9 6.4 4.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CorA PF01544.18 EJP63353.1 - 5.3e-14 52.2 0.2 8.3e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Stimulus_sens_1 PF13756.6 EJP63353.1 - 0.19 12.3 1.1 1.3 9.6 0.1 2.9 2 1 0 2 2 2 0 Stimulus-sensing domain ABC_tran PF00005.27 EJP63354.1 - 2.6e-46 157.5 0.0 3.3e-25 89.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP63354.1 - 5.3e-33 114.8 33.0 1.9e-23 83.5 13.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP63354.1 - 2.6e-15 56.5 1.9 0.0012 18.3 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP63354.1 - 1.7e-09 37.9 0.0 0.0067 16.3 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EJP63354.1 - 1e-07 31.7 0.0 0.0011 18.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJP63354.1 - 1.8e-07 30.8 1.9 0.0013 18.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP63354.1 - 3.9e-07 30.1 0.1 0.0039 17.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EJP63354.1 - 1.6e-06 28.6 0.3 0.03 14.7 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 EJP63354.1 - 1.6e-06 28.4 1.0 0.026 14.8 0.1 3.4 3 1 0 3 3 3 2 AAA domain NB-ARC PF00931.22 EJP63354.1 - 2.8e-06 26.7 0.3 8.2e-05 21.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.6 EJP63354.1 - 1e-05 26.1 2.0 0.0044 17.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EJP63354.1 - 4.3e-05 23.6 0.1 0.059 13.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 EJP63354.1 - 0.00023 20.3 0.1 0.046 12.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.6 EJP63354.1 - 0.00028 20.7 0.0 0.66 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 EJP63354.1 - 0.00032 20.3 0.1 0.43 10.1 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 EJP63354.1 - 0.00046 20.4 5.2 0.0078 16.3 0.3 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Pox_A32 PF04665.12 EJP63354.1 - 0.00065 19.2 0.4 0.34 10.3 0.1 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein SbcCD_C PF13558.6 EJP63354.1 - 0.00066 19.9 0.2 0.26 11.6 0.1 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit GTP_EFTU PF00009.27 EJP63354.1 - 0.00071 19.2 0.3 0.67 9.5 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EJP63354.1 - 0.00079 19.1 1.3 0.31 10.6 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EJP63354.1 - 0.00089 19.4 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EJP63354.1 - 0.00092 19.2 0.2 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MobB PF03205.14 EJP63354.1 - 0.002 18.0 0.9 0.75 9.7 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 EJP63354.1 - 0.0037 16.7 2.0 0.24 10.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 EJP63354.1 - 0.0038 17.0 0.4 1 9.0 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein Dynamin_N PF00350.23 EJP63354.1 - 0.0046 17.0 0.6 0.3 11.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Roc PF08477.13 EJP63354.1 - 0.0057 16.9 0.1 1.9 8.7 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EJP63354.1 - 0.006 16.3 0.4 0.57 9.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EJP63354.1 - 0.012 15.3 0.1 0.41 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EJP63354.1 - 0.022 14.4 0.0 7.9 6.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TrwB_AAD_bind PF10412.9 EJP63354.1 - 0.027 13.4 2.1 2.2 7.1 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EJP63354.1 - 0.037 14.4 1.0 20 5.6 0.0 3.7 4 0 0 4 4 3 0 RNA helicase AAA_5 PF07728.14 EJP63354.1 - 0.041 13.9 0.1 10 6.1 0.0 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EJP63354.1 - 0.044 14.1 0.4 6.7 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 EJP63354.1 - 0.062 13.0 0.1 17 5.0 0.0 2.8 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EJP63354.1 - 0.071 12.4 0.1 8.8 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EJP63354.1 - 0.14 12.7 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EJP63354.1 - 0.14 12.0 0.1 9.4 6.1 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Septin PF00735.18 EJP63354.1 - 0.17 11.1 0.3 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_11 PF13086.6 EJP63354.1 - 0.18 11.5 0.0 5.5 6.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EJP63354.1 - 0.19 11.4 0.3 18 5.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.29 EJP63354.1 - 0.22 11.3 0.5 15 5.3 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase ATPase PF06745.13 EJP63354.1 - 0.22 10.9 0.9 7.8 5.8 0.0 2.3 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.15 EJP63354.1 - 0.26 11.2 4.2 21 4.9 0.1 3.3 3 0 0 3 3 3 0 NTPase ABC_ATPase PF09818.9 EJP63354.1 - 2.8 6.6 4.3 0.72 8.6 0.1 2.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ERCC4 PF02732.15 EJP63355.1 - 8.3e-20 71.6 0.0 2.8e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain DUF4780 PF16012.5 EJP63355.1 - 0.029 13.8 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4780) SDA1 PF05285.12 EJP63357.1 - 0.026 13.9 37.5 0.035 13.5 37.5 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EJP63357.1 - 1.3 8.3 36.0 1.6 8.0 36.0 1.1 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 EJP63357.1 - 2.9 6.9 14.7 4 6.4 14.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 EJP63357.1 - 4.2 6.0 11.3 6.8 5.3 11.3 1.4 1 0 0 1 1 1 0 Presenilin WH1 PF00568.23 EJP63358.1 - 1.9e-26 92.2 0.1 2.5e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EJP63358.1 - 2.2e-05 24.1 0.9 4.8e-05 23.1 0.9 1.6 1 0 0 1 1 1 1 WH2 motif eIF-1a PF01176.19 EJP63359.1 - 1.2e-20 73.0 0.0 1.8e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 GST_N PF02798.20 EJP63360.1 - 4e-14 52.7 0.0 7.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EJP63360.1 - 3.5e-12 46.6 0.0 1.2e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP63360.1 - 8e-09 35.7 0.0 1.8e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP63360.1 - 7.2e-07 29.1 0.1 1.9e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP63360.1 - 1.7e-06 28.1 0.0 4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EJP63360.1 - 4e-06 27.0 0.0 9.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YAcAr PF10686.9 EJP63360.1 - 0.025 14.5 0.7 1.5 8.8 0.1 2.8 2 1 0 2 2 2 0 YspA, cpYpsA-related SLOG family SET PF00856.28 EJP63361.1 - 3.4e-15 56.8 0.1 5.1e-14 53.0 0.0 2.7 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 EJP63361.1 - 0.002 18.1 13.2 0.025 14.7 0.3 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EJP63361.1 - 0.0034 17.1 9.1 1.5 8.8 0.2 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP63361.1 - 0.017 15.3 5.0 1.3 9.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EJP63361.1 - 4.9 7.5 9.3 1 9.7 2.8 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S9 PF00326.21 EJP63362.1 - 6.2e-41 140.2 0.0 1e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EJP63362.1 - 0.013 15.4 0.0 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 EJP63362.1 - 0.067 12.7 0.0 0.5 9.9 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family GST_C PF00043.25 EJP63363.1 - 1e-05 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EJP63363.1 - 0.00019 21.4 0.0 0.00062 19.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP63363.1 - 0.00044 20.4 0.0 0.00094 19.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EJP63363.1 - 0.048 14.1 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain CFEM PF05730.11 EJP63364.1 - 4.8e-12 45.8 9.3 8e-12 45.1 9.3 1.4 1 0 0 1 1 1 1 CFEM domain Plasmodium_Vir PF05795.11 EJP63364.1 - 0.031 13.7 1.8 0.039 13.4 1.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SKG6 PF08693.10 EJP63364.1 - 0.086 12.3 0.1 0.24 10.8 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SPX PF03105.19 EJP63364.1 - 5.6 6.8 11.5 6.7 6.5 11.5 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 EJP63364.1 - 8.2 4.9 7.2 8.5 4.8 7.2 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EJP63364.1 - 8.5 5.1 8.0 9.2 5.0 8.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4396 PF14342.6 EJP63366.1 - 4.2e-45 153.6 4.1 6.7e-45 152.9 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) PRP21_like_P PF12230.8 EJP63367.1 - 5.6e-54 183.3 8.1 1.9e-53 181.6 8.1 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EJP63367.1 - 3.9e-40 135.6 2.0 4.4e-20 71.4 0.1 2.8 2 0 0 2 2 2 2 Surp module PX PF00787.24 EJP63367.1 - 2.1e-24 85.7 0.3 5.6e-24 84.3 0.0 2.0 2 0 0 2 2 2 1 PX domain zf_UBZ PF18439.1 EJP63367.1 - 0.0026 17.3 0.9 0.0059 16.2 0.9 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger PMT PF02366.18 EJP63368.1 - 3e-78 262.8 14.9 7.1e-78 261.6 14.9 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EJP63368.1 - 4.6e-66 222.2 9.5 4.6e-66 222.2 9.5 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EJP63368.1 - 8.6e-46 156.1 0.0 1.7e-45 155.2 0.0 1.5 1 0 0 1 1 1 1 MIR domain Sec2p PF06428.11 EJP63369.1 - 9e-25 86.5 18.2 9e-25 86.5 18.2 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF5401 PF17380.2 EJP63369.1 - 0.66 8.0 16.4 0.97 7.4 16.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) 4HBT_3 PF13622.6 EJP63370.1 - 1.9e-28 100.4 0.0 2.2e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily PNP_UDP_1 PF01048.20 EJP63371.1 - 0.062 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily Asp PF00026.23 EJP63372.1 - 8.2e-53 179.9 5.2 1.3e-52 179.2 5.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP63372.1 - 1.7e-09 38.2 0.6 2.7e-06 27.7 0.4 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP63372.1 - 0.0067 17.1 0.4 4.1 8.1 0.2 3.2 2 1 0 2 2 2 2 Aspartyl protease HTH_psq PF05225.16 EJP63374.1 - 2.3e-08 33.6 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EJP63374.1 - 3e-05 24.0 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 EJP63374.1 - 0.045 13.6 0.2 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_30 PF13556.6 EJP63374.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_1 PF01527.20 EJP63374.1 - 0.13 12.6 0.6 1 9.7 0.6 2.2 1 1 0 1 1 1 0 Transposase HTH_7 PF02796.15 EJP63374.1 - 0.13 12.3 0.2 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SNARE PF05739.19 EJP63375.1 - 2.7e-13 49.7 0.1 5.8e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EJP63375.1 - 1.5e-08 33.7 0.1 3.3e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 EJP63375.1 - 0.0002 21.1 6.8 0.0015 18.2 0.0 3.1 2 1 1 3 3 3 1 Syntaxin KxDL PF10241.9 EJP63375.1 - 0.00098 19.4 1.5 0.51 10.6 0.5 3.2 3 1 0 3 3 3 2 Uncharacterized conserved protein Prominin PF05478.11 EJP63375.1 - 0.0067 14.5 0.8 1 7.2 0.3 2.2 2 0 0 2 2 2 2 Prominin SOAR PF16533.5 EJP63375.1 - 0.024 14.6 1.3 0.18 11.8 0.0 2.5 2 1 0 2 2 2 0 STIM1 Orai1-activating region MCPsignal PF00015.21 EJP63375.1 - 0.18 11.6 6.0 0.1 12.4 0.5 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-18_N PF10496.9 EJP63375.1 - 0.93 9.8 3.2 1.1 9.5 0.3 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus An_peroxidase PF03098.15 EJP63377.1 - 3.2e-115 385.7 0.0 3.7e-115 385.5 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Senescence PF06911.12 EJP63380.1 - 3.9e-53 180.5 2.5 5.8e-53 179.9 2.5 1.3 1 0 0 1 1 1 1 Senescence-associated protein GCP_N_terminal PF17681.1 EJP63381.1 - 5.8e-29 101.7 0.0 8.8e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EJP63381.1 - 7.3e-18 65.1 0.0 1.7e-17 63.8 0.0 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal SH3_2 PF07653.17 EJP63382.1 - 6.7e-10 38.5 0.1 1.2e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EJP63382.1 - 1.6e-08 34.0 0.2 1.6e-08 34.0 0.2 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EJP63382.1 - 9.2e-08 31.8 0.3 1.9e-07 30.8 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain CHAP PF05257.16 EJP63382.1 - 0.15 12.6 0.1 0.35 11.5 0.1 1.6 1 0 0 1 1 1 0 CHAP domain Asp PF00026.23 EJP63383.1 - 4.7e-60 203.7 6.4 5.5e-60 203.4 6.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP63383.1 - 4.1e-12 46.7 2.8 2.6e-07 31.1 0.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Catalase-rel PF06628.12 EJP63384.1 - 0.082 13.1 0.1 42 4.4 0.0 3.6 3 1 0 3 3 3 0 Catalase-related immune-responsive RPAP2_Rtr1 PF04181.13 EJP63385.1 - 2.6e-22 78.9 0.0 4.8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF4241 PF14025.6 EJP63385.1 - 0.047 14.0 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Ribosomal_S17e PF00833.18 EJP63386.1 - 7.6e-60 200.2 0.1 8.6e-60 200.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 EJP63387.1 - 9.8e-118 393.9 0.0 1.1e-117 393.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit TGT PF01702.18 EJP63388.1 - 4.7e-134 447.0 0.0 5.3e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Hist_deacetyl PF00850.19 EJP63389.1 - 1.4e-51 175.8 0.3 2.1e-51 175.3 0.3 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PHP PF02811.19 EJP63390.1 - 1.4e-13 51.5 0.0 2.2e-13 50.9 0.0 1.3 1 1 0 1 1 1 1 PHP domain Thiolase_N PF00108.23 EJP63391.1 - 1.4e-12 47.6 0.0 7.4e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EJP63391.1 - 9.5e-11 41.4 0.1 7.2e-10 38.6 0.0 2.1 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EJP63391.1 - 1.7e-06 27.8 0.0 0.00029 20.6 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EJP63391.1 - 0.0017 18.0 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF3208 PF11482.8 EJP63391.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) 4HBT_3 PF13622.6 EJP63392.1 - 3e-52 178.3 9.6 5.2e-52 177.6 9.6 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EJP63392.1 - 4.4e-19 68.6 0.0 7.8e-10 38.7 0.0 4.0 3 1 1 4 4 4 3 Acyl-CoA thioesterase 4HBT PF03061.22 EJP63392.1 - 0.041 14.2 0.0 0.99 9.8 0.0 2.3 2 0 0 2 2 2 0 Thioesterase superfamily BTB PF00651.31 EJP63395.1 - 0.089 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain K-cyclin_vir_C PF09080.10 EJP63398.1 - 1.6 9.1 4.1 2.1 8.8 0.6 2.4 2 1 0 2 2 2 0 K cyclin, C terminal GATase_6 PF13522.6 EJP63399.1 - 4.2e-12 46.4 0.0 1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EJP63399.1 - 8.1e-10 38.7 0.0 1.8e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EJP63399.1 - 3.3e-06 26.7 0.2 7.9e-06 25.5 0.2 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EJP63399.1 - 0.083 11.8 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II ADH_zinc_N PF00107.26 EJP63399.1 - 0.13 12.3 0.1 4.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ABC_tran PF00005.27 EJP63400.1 - 2.5e-48 164.1 0.3 2.3e-25 89.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EJP63400.1 - 7e-24 85.2 2.8 8.4e-06 25.8 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EJP63400.1 - 1.5e-23 83.5 34.2 7.5e-17 61.4 21.7 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 EJP63400.1 - 3.8e-08 33.0 4.7 0.097 12.1 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP63400.1 - 8.2e-08 31.9 4.4 0.00049 19.8 1.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EJP63400.1 - 4e-05 24.2 6.8 0.069 13.6 1.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EJP63400.1 - 0.00035 20.2 0.7 0.52 9.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EJP63400.1 - 0.00047 20.0 0.3 0.68 9.6 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EJP63400.1 - 0.0014 18.6 0.2 2.3 8.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EJP63400.1 - 0.012 16.0 0.2 5 7.5 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 EJP63400.1 - 0.017 14.8 4.5 2.5 7.8 0.3 2.9 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 EJP63400.1 - 0.044 14.0 0.1 31 4.9 0.0 3.8 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EJP63400.1 - 0.053 13.4 0.1 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 EJP63400.1 - 0.071 12.7 0.6 12 5.5 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 EJP63400.1 - 0.12 12.1 0.9 13 5.5 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_22 PF13401.6 EJP63400.1 - 0.18 12.1 1.4 9.3 6.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EJP63400.1 - 0.19 12.0 0.8 17 5.6 0.7 2.4 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 EJP63400.1 - 0.2 11.0 1.3 4.6 6.5 0.3 2.3 2 0 0 2 2 2 0 AIG1 family Mg_chelatase PF01078.21 EJP63400.1 - 0.54 9.6 1.8 51 3.1 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SR-25 PF10500.9 EJP63400.1 - 5.9 6.4 7.5 0.48 10.0 2.7 1.5 2 0 0 2 2 1 0 Nuclear RNA-splicing-associated protein Pyridoxal_deC PF00282.19 EJP63401.1 - 1.1e-73 248.1 0.0 7.7e-73 245.3 0.0 1.9 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EJP63401.1 - 2.4e-08 33.6 0.0 3.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EJP63401.1 - 0.00081 18.4 0.0 0.0016 17.4 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V SepSecS PF05889.13 EJP63401.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Evr1_Alr PF04777.13 EJP63404.1 - 2.5e-27 95.3 0.1 4.2e-27 94.5 0.0 1.4 1 1 0 1 1 1 1 Erv1 / Alr family McrBC PF10117.9 EJP63404.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component Proteasome PF00227.26 EJP63405.1 - 9.9e-46 155.6 0.2 1.1e-45 155.4 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 EJP63406.1 - 6.8e-41 140.3 11.1 9.9e-25 87.8 0.1 3.1 3 1 1 4 4 4 2 Cyclin Cwf_Cwc_15 PF04889.12 EJP63406.1 - 0.00034 20.4 2.5 0.00059 19.7 2.5 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 EJP63406.1 - 0.17 11.5 1.9 0.19 11.3 0.5 1.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Pkinase PF00069.25 EJP63408.1 - 1.6e-10 40.8 0.0 1.9e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP63408.1 - 0.0097 15.2 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase bacHORMA_2 PF18173.1 EJP63408.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial HORMA domain 2 Tyrosinase PF00264.20 EJP63409.1 - 1.5e-47 162.8 4.3 2.7e-47 161.9 4.3 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EJP63409.1 - 1.1e-28 100.4 0.0 1.8e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain RNA_pol_Rpb2_6 PF00562.28 EJP63410.1 - 1.2e-112 376.8 0.0 1.7e-112 376.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EJP63410.1 - 6.6e-35 120.5 0.0 1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EJP63410.1 - 1.8e-28 98.5 0.0 4.8e-28 97.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EJP63410.1 - 6.8e-25 87.8 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EJP63410.1 - 1.1e-23 82.9 0.0 2.6e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EJP63410.1 - 5.4e-16 58.8 0.0 7.8e-15 55.1 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 DUF570 PF04489.13 EJP63410.1 - 0.068 11.8 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Rpr2 PF04032.16 EJP63410.1 - 0.17 12.2 0.4 0.36 11.2 0.4 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Arf PF00025.21 EJP63411.1 - 4.3e-41 140.3 0.0 5.1e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EJP63411.1 - 3.3e-17 62.6 0.0 4.2e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP63411.1 - 1.4e-14 54.3 0.0 2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EJP63411.1 - 1.2e-06 28.6 0.0 1.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EJP63411.1 - 7.7e-06 25.3 0.0 3.1e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EJP63411.1 - 1.2e-05 24.9 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EJP63411.1 - 1.2e-05 24.9 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EJP63411.1 - 0.0062 16.1 0.3 0.014 14.9 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EJP63411.1 - 0.01 15.9 0.1 0.033 14.3 0.2 1.6 1 1 1 2 2 2 0 Dynamin family Beta_elim_lyase PF01212.21 EJP63412.1 - 3.2e-71 240.0 0.0 3.8e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EJP63412.1 - 5.6e-08 32.3 0.0 7.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EJP63412.1 - 2.1e-05 23.2 0.0 5.1e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EJP63412.1 - 0.0033 16.8 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.28 EJP63413.1 - 2.9e-144 480.8 0.0 3.4e-76 256.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EJP63413.1 - 3.3e-51 174.4 0.0 1.4e-28 99.9 0.0 3.9 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EJP63413.1 - 5.5e-22 77.9 4.3 4.4e-11 43.0 0.8 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP63413.1 - 1e-07 32.8 0.1 2.7e-05 25.1 0.0 3.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EJP63414.1 - 1.2e-38 133.0 60.0 3.8e-37 128.0 60.0 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP63414.1 - 1.6e-10 40.4 13.3 1.6e-10 40.4 13.3 3.8 2 1 2 4 4 4 1 Sugar (and other) transporter Gram_pos_anchor PF00746.21 EJP63414.1 - 3 7.9 8.0 2.4 8.2 0.5 3.5 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Fungal_trans_2 PF11951.8 EJP63416.1 - 6.4e-46 156.9 1.2 6.4e-46 156.9 1.2 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63416.1 - 4.2e-06 26.8 7.6 8.7e-06 25.8 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.19 EJP63416.1 - 0.27 11.8 1.9 0.78 10.4 1.9 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Dabb PF07876.12 EJP63417.1 - 1.4e-10 41.6 0.0 1.8e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Z1 PF10593.9 EJP63417.1 - 0.21 11.0 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Z1 domain Macoilin PF09726.9 EJP63418.1 - 0.35 9.4 23.2 0.45 9.0 23.2 1.3 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 EJP63418.1 - 0.48 9.6 32.5 0.62 9.2 32.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SAPS PF04499.15 EJP63418.1 - 0.54 9.0 5.3 0.59 8.8 5.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 EJP63418.1 - 0.56 9.0 25.2 0.68 8.7 25.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 EJP63418.1 - 0.64 9.9 26.5 0.81 9.5 26.5 1.2 1 0 0 1 1 1 0 SPX domain DAG_kinase_N PF14513.6 EJP63418.1 - 0.8 9.9 5.7 1.6 8.9 5.7 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Utp14 PF04615.13 EJP63418.1 - 0.81 8.2 9.9 0.93 8.0 9.9 1.0 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.13 EJP63418.1 - 1.3 8.5 8.9 1.6 8.3 8.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Smg8_Smg9 PF10220.9 EJP63418.1 - 2.8 6.1 9.9 3.1 6.0 9.9 1.0 1 0 0 1 1 1 0 Smg8_Smg9 QWRF PF04484.12 EJP63418.1 - 3.1 7.4 24.6 4.3 7.0 24.6 1.4 1 0 0 1 1 1 0 QWRF family Raftlin PF15250.6 EJP63418.1 - 4.5 5.9 7.4 4.9 5.8 7.4 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 EJP63418.1 - 5.9 5.5 14.8 8.1 5.1 14.8 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 EJP63418.1 - 9.9 6.6 14.1 1.6e+02 2.6 14.1 2.2 1 1 0 1 1 1 0 RNA polymerase III RPC4 HET PF06985.11 EJP63419.1 - 1.1e-10 42.0 8.6 2.6e-08 34.3 2.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) UPF0121 PF03661.13 EJP63420.1 - 8.5e-30 103.9 1.4 1.1e-29 103.5 1.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Phage_holin_3_1 PF05106.12 EJP63420.1 - 0.17 12.3 3.6 0.33 11.4 1.6 2.2 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) DSPc PF00782.20 EJP63422.1 - 7.9e-08 32.2 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJP63422.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EJP63422.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EJP63422.1 - 0.055 13.4 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Podoplanin PF05808.11 EJP63422.1 - 5.3 7.1 6.2 11 6.1 6.2 1.4 1 0 0 1 1 1 0 Podoplanin Cyclin_N PF00134.23 EJP63423.1 - 1.1e-09 38.2 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain RAM PF15320.6 EJP63423.1 - 1.5 9.5 12.0 5.2 7.7 12.0 2.0 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein NTP_transferase PF00483.23 EJP63425.1 - 3.4e-40 138.2 0.0 6e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EJP63425.1 - 7.2e-07 29.7 0.2 1.6e-06 28.5 0.2 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 EJP63425.1 - 0.00015 21.7 0.1 0.00027 20.8 0.1 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NYD-SP28_assoc PF14775.6 EJP63425.1 - 0.59 10.3 5.0 2.6 8.2 0.7 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain MAD PF05557.13 EJP63426.1 - 5.9e-64 216.6 54.9 3e-63 214.2 52.8 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein Methyltransf_25 PF13649.6 EJP63426.1 - 0.64 10.8 3.2 8.7 7.1 0.4 3.3 2 0 0 2 2 2 0 Methyltransferase domain muHD PF10291.9 EJP63427.1 - 3e-65 220.3 0.0 5.9e-65 219.3 0.0 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EJP63427.1 - 3.9e-09 36.7 0.4 9e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 EJP63427.1 - 8.2e-09 35.5 2.6 1.7e-08 34.4 2.6 1.4 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EJP63427.1 - 0.0028 17.4 1.0 0.0043 16.8 1.0 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Muted PF14942.6 EJP63427.1 - 0.065 13.6 5.2 0.046 14.1 2.1 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Vps5 PF09325.10 EJP63427.1 - 0.14 11.7 4.6 0.07 12.7 1.8 1.8 2 0 0 2 2 2 0 Vps5 C terminal like Pkinase PF00069.25 EJP63428.1 - 2.5e-31 109.0 0.0 3.2e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP63428.1 - 1.2e-10 41.1 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP63428.1 - 0.0094 15.9 0.4 0.26 11.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family KIX_2 PF16987.5 EJP63428.1 - 0.012 15.6 0.1 0.06 13.4 0.1 2.1 1 1 0 1 1 1 0 KIX domain Kinase-like PF14531.6 EJP63428.1 - 0.016 14.6 0.0 0.049 12.9 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 EJP63428.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 EJP63429.1 - 1.4e-08 34.9 9.2 3.4e-08 33.7 9.2 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EJP63429.1 - 1.5e-05 25.1 8.5 4.1e-05 23.7 8.5 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EJP63429.1 - 0.00031 21.0 7.7 0.00086 19.5 7.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EJP63429.1 - 0.00038 20.3 10.1 0.00094 19.0 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EJP63429.1 - 0.00051 20.0 2.7 0.0012 18.8 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EJP63429.1 - 0.0026 17.9 7.8 0.0074 16.4 7.8 1.9 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.22 EJP63429.1 - 0.003 17.4 2.7 0.003 17.4 2.7 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 EJP63429.1 - 0.01 15.5 5.3 0.024 14.3 5.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EJP63429.1 - 0.019 14.8 8.6 0.044 13.6 8.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP63429.1 - 0.026 14.4 5.9 0.052 13.4 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EJP63429.1 - 0.069 13.5 8.2 0.15 12.4 8.2 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 EJP63429.1 - 0.55 10.2 6.4 1.7 8.6 6.4 1.8 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Prok-RING_4 PF14447.6 EJP63429.1 - 0.72 9.8 6.5 2.2 8.2 6.5 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EJP63429.1 - 1.4 8.9 9.1 3 7.9 9.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 EJP63429.1 - 2.5 8.1 7.0 5.3 7.0 7.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EJP63429.1 - 6.7 6.6 8.0 2.5e+02 1.6 8.0 2.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain LapA_dom PF06305.11 EJP63430.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 EJP63431.1 - 1.4e-33 116.3 40.7 3.6e-32 111.7 40.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP63431.1 - 1.9e-05 23.7 12.6 1.9e-05 23.7 12.6 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter HlyIII PF03006.20 EJP63431.1 - 0.031 14.0 0.5 0.031 14.0 0.5 3.2 3 1 0 3 3 3 0 Haemolysin-III related DUF2894 PF11445.8 EJP63432.1 - 0.0088 16.5 2.4 0.0088 16.5 2.4 3.7 3 2 0 3 3 3 2 Protein of unknown function (DUF2894) DDHD PF02862.17 EJP63432.1 - 7.1 6.7 9.5 0.61 10.2 4.0 2.0 2 0 0 2 2 2 0 DDHD domain Ribosomal_L28 PF00830.19 EJP63433.1 - 0.02 15.1 0.3 0.026 14.7 0.3 1.2 1 0 0 1 1 1 0 Ribosomal L28 family Pap_E4 PF02711.14 EJP63433.1 - 1.7 9.6 7.6 2.4 9.2 7.6 1.2 1 0 0 1 1 1 0 E4 protein Hid1 PF12722.7 EJP63433.1 - 4.4 5.3 5.5 4.6 5.3 5.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BPL_N PF09825.9 EJP63434.1 - 2e-13 50.2 0.1 9.7e-11 41.4 0.0 2.1 1 1 1 2 2 2 2 Biotin-protein ligase, N terminal AMP-binding PF00501.28 EJP63435.1 - 4.4e-65 219.9 0.0 2.5e-64 217.4 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EJP63435.1 - 5.7e-11 42.6 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 EJP63435.1 - 2.3e-09 36.6 3.6 0.019 14.7 0.0 6.1 6 0 0 6 6 6 3 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 EJP63435.1 - 0.031 15.3 0.0 0.071 14.1 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 EJP63435.1 - 4.3 7.2 7.1 13 5.6 0.1 4.5 5 0 0 5 5 5 0 Hexapeptide repeat of succinyl-transferase FAD_binding_4 PF01565.23 EJP63436.1 - 2.1e-22 79.3 0.7 4.4e-22 78.3 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP63436.1 - 1.4e-11 44.3 0.0 2.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 EJP63437.1 - 1.9e-67 228.0 0.0 2.5e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L1 PF00687.21 EJP63440.1 - 9.2e-68 228.0 1.8 9.2e-68 228.0 1.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.15 EJP63441.1 - 2.3e-78 263.4 0.0 3e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EJP63441.1 - 0.015 15.0 0.2 0.027 14.1 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 EJP63441.1 - 0.042 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 EJP63441.1 - 0.21 11.4 0.4 1.7 8.4 0.4 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Fungal_trans PF04082.18 EJP63442.1 - 2.8e-23 82.3 0.1 4.4e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63442.1 - 8.4e-06 25.8 9.7 1.5e-05 25.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EJP63443.1 - 3.3e-15 55.9 49.2 7.7e-14 51.4 48.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP63443.1 - 0.00011 21.3 12.1 0.00011 21.3 12.1 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EJP63443.1 - 2.6 6.2 15.3 0.86 7.8 1.7 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2530 PF10745.9 EJP63443.1 - 2.9 8.2 8.9 0.35 11.1 0.4 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Polysacc_deac_1 PF01522.21 EJP63444.1 - 9.4e-21 74.0 0.0 1.6e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EJP63444.1 - 0.023 13.9 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 YbjQ_1 PF01906.17 EJP63446.1 - 8.6e-25 87.4 0.2 1e-24 87.1 0.2 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding Trehalase PF01204.18 EJP63447.1 - 1.8e-117 393.3 9.6 1.3e-116 390.4 9.6 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 EJP63447.1 - 0.00048 19.2 0.7 0.002 17.1 0.1 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Cupin_2 PF07883.11 EJP63448.1 - 2.5e-07 30.3 0.0 4.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain CDC37_M PF08565.11 EJP63449.1 - 1.2e-05 25.1 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain DUF4106 PF13388.6 EJP63449.1 - 0.011 15.1 1.5 0.017 14.4 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4106) DUF1502 PF07397.11 EJP63449.1 - 0.19 11.6 2.7 0.53 10.2 2.7 1.8 1 1 0 1 1 1 0 Repeat of unknown function (DUF1502) MFS_1 PF07690.16 EJP63450.1 - 4.2e-13 49.0 16.2 4.2e-13 49.0 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 EJP63451.1 - 7.6e-59 199.1 5.3 9.2e-59 198.8 5.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP63451.1 - 4.4e-46 156.8 5.2 5.3e-46 156.5 5.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP63451.1 - 1.1e-15 58.0 5.3 1.6e-15 57.5 5.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP63451.1 - 0.00035 20.1 1.7 0.00085 18.8 1.7 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EJP63451.1 - 0.041 13.0 0.2 0.056 12.6 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_transf_4 PF13439.6 EJP63451.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Ank_2 PF12796.7 EJP63452.1 - 7.2e-37 125.9 20.3 4.8e-06 27.1 0.0 15.0 7 4 11 19 19 19 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP63452.1 - 2.3e-25 88.6 15.0 9.4e-05 22.9 0.0 16.2 15 1 2 17 17 17 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP63452.1 - 1.6e-18 64.8 14.6 1.5 9.6 0.0 19.0 22 0 0 22 22 22 4 Ankyrin repeat Ank_5 PF13857.6 EJP63452.1 - 1.3e-15 57.2 7.5 0.00025 21.2 0.0 12.3 14 2 2 16 16 16 2 Ankyrin repeats (many copies) Ank PF00023.30 EJP63452.1 - 1.4e-10 41.1 26.3 0.41 11.2 0.0 16.0 17 2 1 18 18 18 4 Ankyrin repeat SNF2_N PF00176.23 EJP63453.1 - 9.1e-54 182.5 4.3 2.3e-32 112.1 1.1 2.5 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP63453.1 - 4.7e-20 72.0 2.4 7.7e-20 71.3 0.0 2.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EJP63453.1 - 0.00012 21.4 0.0 0.00037 19.8 0.0 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EJP63453.1 - 0.0008 19.4 0.0 0.047 13.7 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Cytochrom_C_2 PF01322.20 EJP63453.1 - 0.12 13.3 0.0 0.12 13.3 0.0 3.0 4 0 0 4 4 4 0 Cytochrome C' Rieske PF00355.26 EJP63454.1 - 2.2e-09 37.1 0.0 3.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EJP63454.1 - 4.7e-06 26.5 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pro-kuma_activ PF09286.11 EJP63455.1 - 2.2e-36 125.3 0.0 4.9e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP63455.1 - 2e-06 27.3 0.4 3.5e-06 26.5 0.4 1.4 1 0 0 1 1 1 1 Subtilase family Cupin_1 PF00190.22 EJP63456.1 - 3e-39 134.0 0.1 3.2e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EJP63456.1 - 1.5e-24 85.4 0.1 1.6e-12 46.9 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EJP63456.1 - 1.1e-08 34.6 0.2 0.0011 18.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 EJP63456.1 - 9.7e-06 25.6 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase AraC_binding PF02311.19 EJP63456.1 - 8.1e-05 22.5 0.0 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain 3-HAO PF06052.12 EJP63456.1 - 0.00052 19.7 0.0 0.0018 18.0 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.12 EJP63456.1 - 0.051 13.0 0.0 5.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein Auxin_BP PF02041.16 EJP63456.1 - 0.068 12.8 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Auxin binding protein DUF2306 PF10067.9 EJP63457.1 - 3.6e-06 27.2 8.6 2.1e-05 24.7 6.4 2.8 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) MFS_1 PF07690.16 EJP63458.1 - 4.9e-05 22.4 41.0 0.00016 20.8 6.6 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Methyltransf_25 PF13649.6 EJP63459.1 - 2.1e-08 34.7 0.0 4.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP63459.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP63459.1 - 6.6e-05 22.8 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP63459.1 - 0.00018 20.9 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EJP63459.1 - 0.00024 20.9 0.0 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EJP63459.1 - 0.00026 21.6 0.0 0.00058 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EJP63459.1 - 0.00059 20.8 0.0 0.0015 19.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EJP63459.1 - 0.0056 15.9 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.20 EJP63459.1 - 0.0063 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EJP63459.1 - 0.014 15.3 0.0 0.037 14.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 EJP63459.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.19 EJP63459.1 - 0.065 13.3 0.1 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 EJP63459.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EJP63459.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Fibrillarin PF01269.17 EJP63459.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Fungal_trans_2 PF11951.8 EJP63460.1 - 9.5e-11 41.1 0.2 1.4e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63460.1 - 5e-07 29.7 7.7 9.5e-07 28.8 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3724 PF12521.8 EJP63461.1 - 0.47 10.5 2.2 37 4.5 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3724) DUF3328 PF11807.8 EJP63462.1 - 5e-26 91.9 0.4 5e-26 91.9 0.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EJP63463.1 - 2.3e-16 60.2 5.5 7.4e-15 55.3 5.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.20 EJP63464.1 - 1.3e-38 133.5 2.9 2.1e-38 132.9 2.9 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Amnionless PF14828.6 EJP63464.1 - 0.057 12.2 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF3176 PF11374.8 EJP63465.1 - 2.4e-31 108.1 2.0 2.4e-31 108.1 2.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Podoplanin PF05808.11 EJP63465.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Podoplanin tRNA_bind PF01588.20 EJP63466.1 - 6.9e-21 74.2 0.1 1.5e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 EJP63466.1 - 1.2e-06 28.4 0.0 2.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EJP63466.1 - 0.0013 18.9 0.8 0.0029 17.8 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Smac_DIABLO PF09057.10 EJP63466.1 - 1.1 8.5 4.3 1.9 7.8 4.3 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases K_channel_TID PF07941.11 EJP63466.1 - 2.6 8.6 9.6 1.1 9.8 6.8 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain RNA_pol PF00940.19 EJP63467.1 - 3.5e-183 609.1 0.0 5.1e-183 608.6 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EJP63467.1 - 1.8e-94 316.9 3.4 1.8e-94 316.9 3.4 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal RsfS PF02410.15 EJP63468.1 - 6.5e-13 49.0 0.0 1.7e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation NuDC PF16273.5 EJP63468.1 - 7.2 7.2 6.5 1.6 9.3 1.7 2.1 2 0 0 2 2 2 0 Nuclear distribution C domain DHHA2 PF02833.14 EJP63469.1 - 4.7e-36 124.1 0.0 7.7e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EJP63469.1 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 DHH family GATase PF00117.28 EJP63470.1 - 1e-14 54.7 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EJP63470.1 - 0.0084 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EJP63470.1 - 0.023 14.4 0.2 0.13 12.0 0.2 2.2 1 1 0 1 1 1 0 Peptidase C26 CAP_N PF01213.19 EJP63470.1 - 0.025 14.1 0.5 0.034 13.6 0.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glycophorin_A PF01102.18 EJP63471.1 - 0.018 15.3 0.1 0.032 14.5 0.1 1.4 1 0 0 1 1 1 0 Glycophorin A DUF4328 PF14219.6 EJP63471.1 - 0.019 14.5 0.7 0.03 13.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) MGC-24 PF05283.11 EJP63471.1 - 0.051 14.0 11.2 0.12 12.9 11.2 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Syndecan PF01034.20 EJP63471.1 - 0.075 13.0 0.4 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain Phage_holin_2_4 PF16082.5 EJP63471.1 - 0.25 11.1 5.1 0.38 10.5 2.7 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like FSA_C PF10479.9 EJP63471.1 - 3.8 5.5 10.0 4.6 5.2 10.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SKG6 PF08693.10 EJP63471.1 - 6.3 6.3 9.5 12 5.4 9.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SOG2 PF10428.9 EJP63472.1 - 0.2 10.8 15.1 0.22 10.7 15.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4614 PF15391.6 EJP63472.1 - 0.81 9.7 11.3 1.2 9.1 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) QWRF PF04484.12 EJP63472.1 - 0.96 9.1 11.3 1.1 8.9 11.3 1.2 1 0 0 1 1 1 0 QWRF family SPX PF03105.19 EJP63472.1 - 3.2 7.6 13.8 3.5 7.4 13.8 1.0 1 0 0 1 1 1 0 SPX domain SpoIIIAH PF12685.7 EJP63472.1 - 3.9 7.3 8.6 4.7 7.0 8.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein MFS_1 PF07690.16 EJP63473.1 - 1.8e-14 53.5 55.5 6.2e-13 48.4 53.8 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 EJP63473.1 - 0.00076 18.6 15.7 0.00084 18.4 3.3 3.2 3 1 0 3 3 3 1 PUCC protein SieB PF14163.6 EJP63473.1 - 0.29 10.6 4.0 0.45 10.0 2.6 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B TMEM190 PF15431.6 EJP63473.1 - 0.42 10.8 1.7 4.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Transmembrane protein 190 TauD PF02668.16 EJP63475.1 - 3.7e-63 213.8 2.1 4.6e-63 213.5 2.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HA2 PF04408.23 EJP63477.1 - 2.8e-22 79.1 0.1 2.8e-22 79.1 0.1 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EJP63477.1 - 6.2e-22 77.8 0.0 1.3e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EJP63477.1 - 2.2e-13 50.5 0.0 5.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EJP63477.1 - 2.1e-12 47.2 0.2 4.4e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 EJP63477.1 - 7.3e-06 26.3 0.0 2.5e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EJP63477.1 - 2e-05 24.4 0.5 7.5e-05 22.6 0.5 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EJP63477.1 - 9.5e-05 21.6 0.2 0.00025 20.2 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 EJP63477.1 - 9.6e-05 22.2 0.2 0.00029 20.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EJP63477.1 - 0.023 14.7 0.2 0.7 9.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EJP63477.1 - 0.029 14.7 0.1 0.065 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EJP63477.1 - 0.04 13.2 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EJP63477.1 - 0.094 12.2 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AC_N PF16214.5 EJP63477.1 - 8.3 5.4 10.5 14 4.7 10.5 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Pmp3 PF01679.17 EJP63478.1 - 1.5e-20 73.1 8.1 2.1e-20 72.6 8.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.10 EJP63479.1 - 6.2e-101 338.5 0.0 7.5e-101 338.2 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 ADH_zinc_N_2 PF13602.6 EJP63480.1 - 4.3e-10 40.7 0.0 1e-09 39.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP63480.1 - 5.4e-10 39.1 0.0 5.3e-09 35.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain IPK PF03770.16 EJP63481.1 - 9.4e-48 162.7 0.0 1.7e-47 161.9 0.0 1.4 1 1 0 1 1 1 1 Inositol polyphosphate kinase CLP1_P PF16575.5 EJP63482.1 - 2.1e-35 122.2 0.0 3.2e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EJP63482.1 - 2.9e-24 85.7 0.0 9e-24 84.1 0.0 1.8 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EJP63482.1 - 3e-22 78.6 0.0 5.2e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_16 PF13191.6 EJP63482.1 - 0.00027 21.4 0.1 0.0005 20.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 EJP63482.1 - 0.0018 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 EJP63482.1 - 0.019 14.8 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EJP63482.1 - 0.027 14.7 0.2 0.051 13.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EJP63482.1 - 0.075 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EJP63482.1 - 0.21 11.6 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.14 EJP63483.1 - 2.2e-13 50.1 0.1 2.8e-12 46.5 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP63483.1 - 9.1e-05 21.7 0.1 0.00071 18.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EJP63483.1 - 0.00011 22.2 0.6 0.89 9.5 0.1 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EJP63483.1 - 0.00043 19.6 0.1 0.23 10.7 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP63483.1 - 0.0013 18.9 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EJP63483.1 - 0.017 13.8 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 EJP63483.1 - 0.018 14.1 1.9 0.027 13.6 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EJP63483.1 - 0.035 13.7 1.8 0.16 11.6 0.5 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EJP63483.1 - 0.12 11.4 4.4 3.2 6.7 0.1 3.1 2 1 1 3 3 3 0 Glucose inhibited division protein A ABC2_membrane PF01061.24 EJP63484.1 - 1.2e-86 289.5 57.8 1.4e-47 161.8 12.0 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EJP63484.1 - 9.7e-37 126.5 0.0 2.9e-18 66.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EJP63484.1 - 4e-32 110.0 4.5 1.6e-25 88.8 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EJP63484.1 - 9e-14 51.9 0.3 3.3e-13 50.1 0.3 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EJP63484.1 - 4e-06 26.2 12.2 4e-06 26.2 12.2 3.3 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.6 EJP63484.1 - 8.2e-06 26.3 0.1 0.003 18.0 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EJP63484.1 - 3.1e-05 23.9 0.0 0.00024 21.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 EJP63484.1 - 4.8e-05 23.6 0.1 0.12 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EJP63484.1 - 5.9e-05 23.0 0.0 0.097 12.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EJP63484.1 - 9e-05 22.8 0.6 0.0044 17.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 EJP63484.1 - 0.00026 20.6 0.3 0.17 11.5 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EJP63484.1 - 0.001 19.6 0.0 0.059 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EJP63484.1 - 0.0012 18.9 0.5 0.079 13.0 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EJP63484.1 - 0.0016 18.2 0.1 0.38 10.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP63484.1 - 0.0016 18.7 0.0 0.18 12.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EJP63484.1 - 0.0017 18.0 0.2 0.1 12.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EJP63484.1 - 0.002 17.9 0.1 0.14 11.9 0.0 3.2 4 0 0 4 4 3 1 AAA domain TsaE PF02367.17 EJP63484.1 - 0.011 15.7 0.2 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EJP63484.1 - 0.014 15.3 0.8 1 9.2 0.2 2.6 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 EJP63484.1 - 0.017 14.5 0.1 0.2 11.1 0.1 2.7 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EJP63484.1 - 0.023 14.0 0.2 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 EJP63484.1 - 0.024 15.0 0.3 3.9 7.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 EJP63484.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Dynamin_N PF00350.23 EJP63484.1 - 0.19 11.8 0.0 0.65 10.0 0.0 1.9 2 0 0 2 2 1 0 Dynamin family PduV-EutP PF10662.9 EJP63484.1 - 0.19 11.4 0.6 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EJP63484.1 - 0.2 10.9 0.6 0.52 9.5 0.1 1.8 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 EJP63484.1 - 0.24 10.7 0.3 7.3 5.9 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 EJP63484.1 - 0.26 10.4 0.9 3.2 6.9 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 EJP63484.1 - 0.42 10.3 6.3 2.2 8.0 0.3 3.0 3 0 0 3 3 2 0 AAA domain Cwf_Cwc_15 PF04889.12 EJP63484.1 - 9.7 5.8 8.5 1.7 8.3 0.7 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein E1-E2_ATPase PF00122.20 EJP63485.1 - 4.9e-34 117.4 28.4 1.8e-30 105.8 1.5 4.0 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EJP63485.1 - 2.7e-28 98.9 0.7 2.7e-28 98.9 0.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EJP63485.1 - 8e-20 72.0 0.2 1.7e-18 67.7 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EJP63485.1 - 1e-17 63.6 0.0 2.3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EJP63485.1 - 2.1e-12 47.0 0.0 1.1e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EJP63485.1 - 1.4e-05 24.9 0.2 0.00013 21.8 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EJP63485.1 - 0.011 15.6 0.8 0.011 15.6 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) p6 PF17548.2 EJP63485.1 - 0.13 12.3 0.3 0.37 10.8 0.3 1.8 1 0 0 1 1 1 0 Histone-like Protein p6 IncE PF17627.2 EJP63485.1 - 2 8.4 8.8 0.15 12.1 0.6 2.5 2 0 0 2 2 2 0 Inclusion membrane protein E Acid_PPase PF12689.7 EJP63486.1 - 1.5e-59 200.6 0.0 2e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase CRAL_TRIO PF00650.20 EJP63487.1 - 4e-22 78.6 0.0 6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJP63487.1 - 5.5e-10 39.3 0.1 1.1e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DDE_Tnp_1_2 PF13586.6 EJP63487.1 - 0.19 12.1 0.1 0.63 10.4 0.1 1.9 1 0 0 1 1 1 0 Transposase DDE domain FA_desaturase PF00487.24 EJP63488.1 - 9.9e-19 68.2 14.9 9.9e-19 68.2 14.9 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EJP63488.1 - 9.3e-17 61.0 0.0 1.8e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PAD PF03068.15 EJP63489.1 - 2.9e-115 385.4 0.0 4e-115 384.9 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 EJP63489.1 - 0.032 13.9 0.1 0.09 12.4 0.1 1.6 1 1 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain EF-hand_5 PF13202.6 EJP63489.1 - 0.14 11.7 0.1 0.44 10.1 0.1 1.9 1 0 0 1 1 1 0 EF hand RNase_H PF00075.24 EJP63491.1 - 5.9e-10 39.5 0.0 2.6e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EJP63491.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like NACHT PF05729.12 EJP63492.1 - 3.9e-14 52.9 0.1 9.1e-13 48.5 0.0 2.6 2 1 0 2 2 2 1 NACHT domain PGAP1 PF07819.13 EJP63492.1 - 7.1e-05 22.6 0.2 0.00018 21.3 0.1 1.7 2 0 0 2 2 2 1 PGAP1-like protein NB-ARC PF00931.22 EJP63492.1 - 0.00021 20.6 0.1 0.013 14.7 0.0 2.3 1 1 1 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 EJP63492.1 - 0.00028 21.3 0.4 0.0092 16.4 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain AAA PF00004.29 EJP63492.1 - 0.0008 19.8 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EJP63492.1 - 0.001 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF676 PF05057.14 EJP63492.1 - 0.0016 18.0 0.0 0.005 16.4 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 EJP63492.1 - 0.0033 17.7 0.0 0.014 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EJP63492.1 - 0.0037 17.3 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.7 EJP63492.1 - 0.0038 17.9 0.0 0.032 14.8 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.9 EJP63492.1 - 0.01 15.0 0.0 0.047 12.8 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta-hydrolase family Hydrolase_4 PF12146.8 EJP63492.1 - 0.012 14.8 0.0 0.044 13.0 0.0 1.7 1 1 0 2 2 2 0 Serine aminopeptidase, S33 AAA_18 PF13238.6 EJP63492.1 - 0.014 15.9 0.0 0.041 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EJP63492.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF87 PF01935.17 EJP63492.1 - 0.017 15.3 0.0 0.054 13.6 0.0 1.8 1 1 1 2 2 2 0 Helicase HerA, central domain Cutinase PF01083.22 EJP63492.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase Viral_helicase1 PF01443.18 EJP63492.1 - 0.036 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF726 PF05277.12 EJP63492.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RNA_helicase PF00910.22 EJP63492.1 - 0.076 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EJP63492.1 - 0.088 12.5 0.1 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EJP63492.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Fungal_trans PF04082.18 EJP63493.1 - 7.5e-10 38.3 0.1 1.3e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63493.1 - 2.5e-09 37.1 13.3 5.5e-09 36.0 13.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UIM PF02809.20 EJP63493.1 - 0.15 12.0 0.9 0.46 10.5 0.9 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif PUD1_2 PF18457.1 EJP63494.1 - 7.5e-51 172.6 1.0 2.4e-50 170.9 1.0 1.7 1 1 0 1 1 1 1 Up-Regulated in long-lived daf-2 DUF4274 PF14096.6 EJP63496.1 - 1.9e-05 24.5 0.0 48 4.0 0.0 6.3 6 1 1 7 7 7 0 Domain of unknown function (DUF4274) Yqai PF09466.10 EJP63496.1 - 0.00017 21.8 1.9 0.91 9.9 0.4 5.7 5 2 2 7 7 6 1 Hypothetical protein Yqai LpxB PF02684.15 EJP63496.1 - 0.00053 18.9 7.1 0.56 9.0 0.1 5.2 2 1 6 8 8 8 2 Lipid-A-disaccharide synthetase HTH_Tnp_Tc5 PF03221.16 EJP63496.1 - 0.00092 19.2 4.3 2.7 8.1 0.0 6.1 5 3 2 7 7 7 1 Tc5 transposase DNA-binding domain DUF4363 PF14276.6 EJP63496.1 - 0.044 13.9 0.5 6.3 7.0 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4363) SseB_C PF14581.6 EJP63496.1 - 0.071 13.2 3.3 35 4.5 0.1 4.6 2 1 2 5 5 5 0 SseB protein C-terminal domain HMG_box_2 PF09011.10 EJP63496.1 - 0.076 13.6 1.7 4.1 8.1 0.1 3.7 4 1 1 5 5 4 0 HMG-box domain CW_7 PF08230.11 EJP63496.1 - 0.13 12.0 1.8 4.3 7.2 0.1 3.6 3 0 0 3 3 3 0 CW_7 repeat AdoHcyase_NAD PF00670.21 EJP63496.1 - 0.18 11.9 9.7 2.4 8.2 0.1 4.4 1 1 2 4 4 4 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Optomotor-blind PF11078.8 EJP63496.1 - 0.22 12.1 1.5 1.6e+02 3.0 0.0 5.1 7 0 0 7 7 6 0 Optomotor-blind protein N-terminal region Pox_M2 PF04887.12 EJP63496.1 - 0.65 9.5 4.4 4.5 6.7 0.0 3.7 4 1 0 4 4 4 0 Poxvirus M2 protein PglZ PF08665.12 EJP63496.1 - 0.84 9.7 7.0 1.8 8.6 0.1 3.8 4 1 0 4 4 4 0 PglZ domain 1-cysPrx_C PF10417.9 EJP63496.1 - 4.3 7.3 7.7 1.4e+02 2.4 0.0 4.9 5 0 0 5 5 5 0 C-terminal domain of 1-Cys peroxiredoxin Fibrinogen_aC PF12160.8 EJP63496.1 - 9.5 6.2 8.0 44 4.0 0.2 5.3 6 1 1 7 7 7 0 Fibrinogen alpha C domain DUF3723 PF12520.8 EJP63497.1 - 8.4e-12 44.5 0.0 1.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Peptidase_M43 PF05572.13 EJP63498.1 - 7.3e-13 48.7 0.0 2.9e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 EJP63498.1 - 0.00044 19.9 1.2 0.0008 19.1 1.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EJP63498.1 - 0.0043 16.9 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 EJP63498.1 - 0.0059 16.8 0.4 0.015 15.5 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EJP63498.1 - 0.027 15.0 0.3 0.067 13.7 0.3 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SUIM_assoc PF16619.5 EJP63498.1 - 0.053 13.6 2.1 0.2 11.7 2.1 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4953 PF16313.5 EJP63498.1 - 0.06 12.5 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 EJP63498.1 - 0.099 11.6 0.5 0.16 10.9 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 EJP63498.1 - 1.2 7.6 4.9 0.23 10.0 0.4 1.8 2 0 0 2 2 2 0 Putative peptidase family PspA_IM30 PF04012.12 EJP63500.1 - 0.051 13.1 1.7 0.064 12.8 1.7 1.2 1 0 0 1 1 1 0 PspA/IM30 family TarH PF02203.15 EJP63500.1 - 0.072 13.0 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue PurA PF04845.13 EJP63500.1 - 0.072 12.4 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein DcrB PF08786.11 EJP63500.1 - 0.096 12.8 0.4 0.22 11.6 0.2 1.6 2 0 0 2 2 2 0 DcrB DUF21 PF01595.20 EJP63502.1 - 1.8e-34 119.0 0.0 2.8e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EJP63502.1 - 1e-06 29.1 1.3 0.0019 18.6 0.1 3.1 2 0 0 2 2 2 2 CBS domain Lactonase PF10282.9 EJP63503.1 - 2e-14 53.6 0.0 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Drf_GBD PF06371.13 EJP63504.1 - 4.8e-15 55.6 0.3 2.3e-13 50.1 0.3 2.2 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain RraA-like PF03737.15 EJP63505.1 - 2.9e-25 89.2 0.2 4.1e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 Aldolase/RraA Vps36_ESCRT-II PF11605.8 EJP63506.1 - 0.039 14.1 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 EJP63506.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.7 1 1 0 1 1 1 0 Bacterial PH domain UCR_hinge PF02320.16 EJP63507.1 - 2.8e-26 91.5 9.7 2.8e-26 91.5 9.7 2.0 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Mpp10 PF04006.12 EJP63507.1 - 0.073 11.5 21.1 0.087 11.3 21.1 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 EJP63507.1 - 0.16 11.3 22.0 0.18 11.1 22.0 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EJP63507.1 - 0.17 10.1 21.9 0.18 10.0 21.9 1.0 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 EJP63507.1 - 0.18 10.9 10.5 0.2 10.7 10.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CCSAP PF15748.5 EJP63507.1 - 0.63 10.2 12.3 0.73 10.0 12.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DNA_pol_phi PF04931.13 EJP63507.1 - 0.79 7.8 29.7 0.92 7.5 29.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4045 PF13254.6 EJP63507.1 - 1.2 8.7 10.1 1.3 8.5 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Myc_N PF01056.18 EJP63507.1 - 1.8 8.4 17.2 2.4 8.0 17.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region SAPS PF04499.15 EJP63507.1 - 2.2 7.0 9.2 2.1 7.0 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Astro_capsid_p PF12226.8 EJP63507.1 - 2.3 7.3 19.0 3 6.9 19.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SDA1 PF05285.12 EJP63507.1 - 3.5 7.0 24.2 4 6.8 24.2 1.1 1 0 0 1 1 1 0 SDA1 BORG_CEP PF14957.6 EJP63507.1 - 3.5 8.8 6.8 4.7 8.4 6.8 1.3 1 0 0 1 1 1 0 Cdc42 effector CDC45 PF02724.14 EJP63507.1 - 3.7 5.7 16.9 4.1 5.6 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 EJP63507.1 - 4.5 5.9 16.6 5.3 5.7 16.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPL5 PF18168.1 EJP63507.1 - 4.7 6.4 8.0 5.4 6.2 8.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 SLC12 PF03522.15 EJP63507.1 - 5.1 6.0 5.9 5.6 5.9 5.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 EJP63507.1 - 5.2 6.4 12.3 6 6.2 12.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 EJP63507.1 - 6.6 5.4 8.7 6.9 5.3 8.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 EJP63507.1 - 7 5.5 8.1 7.5 5.4 8.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EJP63507.1 - 7.7 5.2 12.6 8.5 5.0 12.6 1.0 1 0 0 1 1 1 0 Presenilin GET2 PF08690.10 EJP63507.1 - 9.3 5.8 6.4 11 5.5 6.4 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 MFS_1 PF07690.16 EJP63508.1 - 2.7e-16 59.4 37.7 3.6e-16 59.1 37.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 EJP63509.1 - 0.018 14.5 0.0 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase KH_1 PF00013.29 EJP63510.1 - 8.9e-95 310.5 24.0 4.8e-15 55.1 0.3 13.7 14 1 0 14 14 14 10 KH domain SLS PF14611.6 EJP63510.1 - 1.2e-13 51.5 5.5 0.013 15.4 0.0 6.9 4 1 3 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EJP63510.1 - 8.4e-11 41.5 25.8 0.021 14.7 0.3 7.9 8 1 0 9 9 9 4 KH domain KH_4 PF13083.6 EJP63510.1 - 3.8e-05 23.5 8.3 0.035 14.0 0.2 5.5 6 0 0 6 6 6 2 KH domain BON PF04972.17 EJP63510.1 - 0.0017 18.6 1.0 14 6.1 0.0 4.2 3 0 0 3 3 3 1 BON domain SIP PF04954.13 EJP63510.1 - 0.0024 18.4 0.2 1.5 9.3 0.0 3.7 3 1 0 3 3 3 1 Siderophore-interacting protein KH_5 PF13184.6 EJP63510.1 - 0.0026 17.8 11.2 12 6.1 0.0 6.3 5 0 0 5 5 5 1 NusA-like KH domain DUF211 PF02680.14 EJP63510.1 - 0.15 12.3 1.1 5.1 7.3 0.2 3.1 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 DUF4604 PF15377.6 EJP63510.1 - 0.28 11.6 0.1 0.28 11.6 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4604) HTH_38 PF13936.6 EJP63511.1 - 0.0022 17.7 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Pkinase PF00069.25 EJP63512.1 - 1.5e-73 247.5 0.0 2e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP63512.1 - 2.9e-47 161.1 0.0 4.4e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EJP63512.1 - 1.5e-18 66.9 0.0 3.7e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EJP63512.1 - 7.5e-08 32.0 0.1 3.7e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EJP63512.1 - 2.9e-07 29.6 0.0 7.1e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EJP63512.1 - 0.0018 17.3 2.2 0.0038 16.2 0.5 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EJP63512.1 - 0.029 13.7 0.1 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP63512.1 - 0.033 14.1 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EJP63512.1 - 0.5 10.0 0.0 0.5 10.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Abhydrolase_4 PF08386.10 EJP63513.1 - 3e-18 65.8 0.0 5.6e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EJP63513.1 - 1.1e-12 48.2 0.0 1.3e-10 41.3 0.0 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold Ysc84 PF04366.12 EJP63514.1 - 3.1e-41 140.1 0.4 5.2e-41 139.4 0.4 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EJP63514.1 - 9.8e-16 57.1 0.2 3.9e-15 55.2 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EJP63514.1 - 4.1e-12 45.6 0.0 7.9e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EJP63514.1 - 4.6e-12 45.6 0.0 7.8e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 EJP63514.1 - 0.02 14.6 0.1 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Synaptobrevin PF00957.21 EJP63515.1 - 0.014 15.2 0.6 0.13 12.1 0.3 2.0 1 1 1 2 2 2 0 Synaptobrevin ArfGap PF01412.18 EJP63516.1 - 2.2e-39 134.2 0.9 3.6e-39 133.5 0.9 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 EJP63516.1 - 0.13 12.1 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain IHABP4_N PF16174.5 EJP63516.1 - 0.39 11.3 3.1 1.1 9.9 3.1 1.7 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SelR PF01641.18 EJP63517.1 - 1.1e-49 167.6 0.1 1.7e-49 166.9 0.1 1.3 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 EJP63517.1 - 0.05 13.6 0.2 6.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 EJP63517.1 - 0.053 13.3 0.1 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 EJP63517.1 - 0.15 12.3 0.4 0.37 11.0 0.4 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ARID PF01388.21 EJP63520.1 - 9.6e-18 64.6 0.1 2.9e-17 63.1 0.1 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PWI PF01480.17 EJP63520.1 - 0.068 13.5 0.1 2.4 8.5 0.0 2.7 2 0 0 2 2 2 0 PWI domain RFX_DNA_binding PF02257.15 EJP63520.1 - 0.12 13.0 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain adh_short_C2 PF13561.6 EJP63521.1 - 2.7e-62 210.4 0.8 3.8e-62 209.9 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP63521.1 - 3.8e-52 176.6 1.1 5.8e-52 176.0 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP63521.1 - 1.6e-12 47.7 0.3 2.7e-12 47.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP63521.1 - 0.00011 21.7 0.2 0.00017 21.1 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP63521.1 - 0.0059 16.0 0.1 0.011 15.2 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EJP63521.1 - 0.0092 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 EJP63521.1 - 0.036 14.8 0.1 0.1 13.3 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain OCD_Mu_crystall PF02423.15 EJP63524.1 - 1.8e-09 37.0 0.0 9.4e-06 24.8 0.0 2.6 2 1 1 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Zn_clus PF00172.18 EJP63525.1 - 3e-09 36.8 6.7 4.8e-09 36.2 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Laminin_II PF06009.12 EJP63525.1 - 0.16 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II Glyco_transf_17 PF04724.13 EJP63526.1 - 4.7e-36 124.6 0.0 2.4e-23 82.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase family 17 Ribosomal_L23eN PF03939.13 EJP63526.1 - 0.48 10.7 2.7 5.1 7.4 0.6 2.6 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain Fungal_trans_2 PF11951.8 EJP63527.1 - 3.1e-10 39.4 0.2 4.8e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63527.1 - 1.2e-05 25.3 1.6 2e-05 24.6 1.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 EJP63527.1 - 0.2 11.4 2.1 0.34 10.7 2.1 1.3 1 0 0 1 1 1 0 Integrin plexin domain RTA1 PF04479.13 EJP63528.1 - 1.4e-63 214.3 17.3 1.4e-63 214.3 17.3 1.7 2 0 0 2 2 2 1 RTA1 like protein RTA1 PF04479.13 EJP63530.1 - 2.1e-70 236.6 11.8 3.3e-70 235.9 11.8 1.3 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.8 EJP63531.1 - 1.6e-08 33.8 0.0 2.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha_adaptin_C PF02296.16 EJP63531.1 - 0.2 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Glyco_hydro_10 PF00331.20 EJP63532.1 - 1.7e-73 247.6 0.0 1.9e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_transf_28 PF03033.20 EJP63533.1 - 3.2e-22 79.1 0.0 5.8e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain VPS13_C PF16909.5 EJP63533.1 - 0.00058 19.7 0.2 0.0012 18.7 0.2 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal UDPGT PF00201.18 EJP63533.1 - 0.00062 18.7 0.0 0.00099 18.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EJP63533.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Peptidase_S8 PF00082.22 EJP63535.1 - 6.8e-16 58.4 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family P-mevalo_kinase PF04275.14 EJP63536.1 - 7.2e-20 71.0 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.27 EJP63536.1 - 9.2e-19 67.5 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 EJP63536.1 - 1.1e-15 57.6 1.6 2.8e-15 56.3 1.6 1.7 1 0 0 1 1 1 1 FAD binding domain PRTase_2 PF15609.6 EJP63536.1 - 0.0008 19.0 0.1 0.05 13.1 0.0 2.7 2 0 0 2 2 2 1 Phosphoribosyl transferase UPRTase PF14681.6 EJP63536.1 - 0.00089 18.7 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Sigma54_activ_2 PF14532.6 EJP63536.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 EJP63536.1 - 0.0059 16.9 0.8 0.02 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EJP63536.1 - 0.0087 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EJP63536.1 - 0.06 13.8 0.0 0.32 11.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EJP63536.1 - 0.066 12.3 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein BON PF04972.17 EJP63536.1 - 0.094 13.0 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 BON domain AAA_18 PF13238.6 EJP63536.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EJP63536.1 - 0.15 12.1 0.0 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Torsin GTP_cyclohydroI PF01227.22 EJP63537.1 - 3.2e-70 235.2 0.0 3.8e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EJP63537.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein CorA PF01544.18 EJP63538.1 - 7.4e-12 45.2 8.3 6.2e-11 42.1 8.3 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FAM199X PF15814.5 EJP63538.1 - 0.14 11.2 0.3 0.18 10.8 0.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X PX PF00787.24 EJP63539.1 - 1.2e-18 67.2 0.1 2.1e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 PX domain ILVD_EDD PF00920.21 EJP63540.1 - 2e-208 693.2 0.3 2.3e-208 693.0 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family AalphaY_MDB PF04611.12 EJP63541.1 - 0.0059 16.6 1.7 0.0067 16.5 0.7 1.6 2 0 0 2 2 2 1 Mating type protein A alpha Y mating type dependent binding region Myb_DNA-binding PF00249.31 EJP63541.1 - 0.009 16.2 0.2 0.1 12.8 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 EJP63541.1 - 0.019 14.6 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 MADF_DNA_bdg PF10545.9 EJP63541.1 - 0.086 13.2 0.1 1 9.7 0.0 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 EJP63542.1 - 8.9e-17 61.0 1.7 5.5e-10 39.3 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP63542.1 - 6.3e-11 42.4 0.6 1.5e-05 25.1 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rod-binding PF10135.9 EJP63542.1 - 0.21 12.2 0.1 0.56 10.8 0.1 1.7 1 1 0 1 1 1 0 Rod binding protein Fungal_trans PF04082.18 EJP63543.1 - 1.4e-12 47.3 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63543.1 - 1.9e-06 27.9 13.7 4.2e-06 26.8 13.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lar_restr_allev PF14354.6 EJP63543.1 - 0.26 11.7 2.5 0.54 10.7 2.5 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Acyl-CoA_dh_1 PF00441.24 EJP63545.1 - 1.2e-19 71.0 0.1 5.4e-19 68.9 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 EJP63545.1 - 1.4e-16 60.8 0.0 3.3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 EJP63545.1 - 3.7e-10 39.9 0.1 9.5e-10 38.6 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EJP63545.1 - 0.004 17.4 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4533 PF15047.6 EJP63545.1 - 0.029 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Tyosinase_C PF18132.1 EJP63546.1 - 6.4e-24 85.0 0.1 1.5e-23 83.8 0.0 1.6 2 0 0 2 2 2 1 Tyosinase C-terminal domain Tyrosinase PF00264.20 EJP63546.1 - 4.1e-18 66.5 4.4 4.1e-18 66.5 4.4 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase OTT_1508_deam PF14441.6 EJP63548.1 - 5.5e-15 55.1 1.3 9.4e-15 54.4 1.3 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Baculo_PEP_C PF04513.12 EJP63549.1 - 0.00059 19.9 10.2 0.067 13.2 2.1 3.8 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 EJP63549.1 - 0.0011 18.9 10.2 0.038 13.9 2.1 2.9 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Collagen_mid PF15984.5 EJP63549.1 - 0.0014 18.4 2.1 0.0027 17.5 2.1 1.5 1 0 0 1 1 1 1 Bacterial collagen, middle region DUF1664 PF07889.12 EJP63549.1 - 0.0016 18.5 7.9 0.065 13.3 0.7 3.9 1 1 3 4 4 4 1 Protein of unknown function (DUF1664) DUF2408 PF10303.9 EJP63549.1 - 0.0033 18.0 4.3 0.34 11.5 0.2 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2408) Fzo_mitofusin PF04799.13 EJP63549.1 - 0.0042 16.6 6.7 0.18 11.4 0.4 3.5 3 1 1 4 4 4 2 fzo-like conserved region DUF4363 PF14276.6 EJP63549.1 - 0.027 14.6 0.4 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Serine_rich PF08824.10 EJP63549.1 - 0.028 14.4 2.1 0.14 12.1 0.2 2.4 3 0 0 3 3 2 0 Serine rich protein interaction domain T3SS_needle_F PF09392.10 EJP63549.1 - 0.036 14.3 1.2 86 3.4 0.0 4.6 3 2 2 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF BshC PF10079.9 EJP63549.1 - 0.083 11.6 2.6 2.7 6.6 0.8 2.2 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC Fib_alpha PF08702.10 EJP63549.1 - 0.09 13.0 4.4 2.5 8.3 0.4 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF883 PF05957.13 EJP63549.1 - 0.18 12.5 9.8 0.58 10.8 1.0 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Phage_Mu_Gam PF07352.12 EJP63549.1 - 0.21 11.5 3.6 5.3 6.9 0.0 3.0 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein HSCB_C PF07743.13 EJP63549.1 - 0.31 11.6 5.7 8.2 7.0 0.7 3.4 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF5339 PF17274.2 EJP63549.1 - 0.58 11.0 2.5 3.7 8.5 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5339) SMBP PF16785.5 EJP63549.1 - 0.7 10.1 9.3 0.72 10.1 0.9 3.8 2 2 1 3 3 3 0 Small metal-binding protein HisKA_3 PF07730.13 EJP63549.1 - 2.4 8.7 12.5 6.6 7.3 0.8 4.4 3 2 1 4 4 4 0 Histidine kinase KxDL PF10241.9 EJP63549.1 - 3.4 8.0 7.4 5.9 7.2 0.6 3.8 2 2 1 4 4 4 0 Uncharacterized conserved protein ABC_tran_CTD PF16326.5 EJP63549.1 - 4 7.7 6.8 15 5.9 0.4 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain HIP1_clath_bdg PF16515.5 EJP63549.1 - 5.5 7.7 8.6 16 6.1 1.6 3.2 2 2 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ank_2 PF12796.7 EJP63550.1 - 4e-41 139.5 1.5 4.6e-14 52.8 0.1 5.4 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EJP63550.1 - 1.7e-31 107.3 7.6 0.00016 21.9 0.4 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EJP63550.1 - 8.4e-31 102.6 1.9 0.00015 21.9 0.0 7.9 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 EJP63550.1 - 1.2e-30 105.5 2.7 3.4e-07 30.7 0.1 6.1 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP63550.1 - 2.8e-22 78.5 5.7 0.00036 20.8 0.1 6.7 5 2 2 7 7 7 7 Ankyrin repeats (many copies) AAA_22 PF13401.6 EJP63550.1 - 0.00021 21.6 0.0 0.00069 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP63550.1 - 0.025 15.0 0.2 0.17 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 EJP63550.1 - 0.028 14.4 0.0 0.088 12.7 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 EJP63550.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EJP63550.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Amidase PF01425.21 EJP63551.1 - 1.1e-45 156.4 0.2 1e-40 140.1 0.1 2.3 2 0 0 2 2 2 2 Amidase Ank_2 PF12796.7 EJP63552.1 - 2e-50 169.3 6.5 2.3e-12 47.3 0.1 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP63552.1 - 1.8e-25 88.9 1.1 7.8e-07 29.5 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP63552.1 - 7.8e-25 86.6 6.7 1.6e-06 28.3 0.0 5.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP63552.1 - 6.8e-24 81.3 2.1 0.018 15.6 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EJP63552.1 - 7.9e-22 76.7 8.3 0.00071 19.9 0.1 6.5 6 0 0 6 6 6 5 Ankyrin repeat F-box-like PF12937.7 EJP63552.1 - 0.04 13.8 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 F-box-like DUF2384 PF09722.10 EJP63552.1 - 0.041 13.9 2.0 26 4.9 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2384) PAD PF03068.15 EJP63553.1 - 1.6e-125 419.2 0.0 2e-125 418.8 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Cu_amine_oxid PF01179.20 EJP63554.1 - 2.4e-116 389.0 0.1 3.7e-116 388.4 0.1 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF3435 PF11917.8 EJP63554.1 - 1.3e-59 202.3 0.4 1.7e-59 201.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF1965 PF09248.10 EJP63554.1 - 8e-29 99.2 0.1 2e-28 97.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EJP63554.1 - 0.00038 20.6 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RRP36 PF06102.12 EJP63554.1 - 0.029 14.3 3.0 0.061 13.3 3.0 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 PHO4 PF01384.20 EJP63555.1 - 1.1e-112 376.4 16.1 1.3e-112 376.2 16.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family FMO-like PF00743.19 EJP63556.1 - 8.5e-26 90.5 0.0 1.6e-19 69.8 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EJP63556.1 - 7.2e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP63556.1 - 5.8e-09 35.6 0.0 7.6e-06 25.4 0.0 3.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP63556.1 - 3.5e-08 33.0 0.0 1.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EJP63556.1 - 6.4e-05 23.1 0.8 0.00083 19.5 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EJP63556.1 - 0.0039 17.2 4.8 0.077 13.0 1.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EJP63556.1 - 0.0045 16.6 2.5 0.75 9.3 0.0 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP63556.1 - 0.012 16.2 0.7 0.2 12.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase bZIP_1 PF00170.21 EJP63557.1 - 6.1e-08 32.7 11.1 1.8e-07 31.2 11.1 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EJP63557.1 - 0.014 15.5 12.1 0.014 15.5 12.1 2.6 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 EJP63557.1 - 0.48 11.0 18.2 0.033 14.7 9.2 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF4407 PF14362.6 EJP63557.1 - 3.3 7.0 9.1 5.9 6.1 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2293 PF10056.9 EJP63558.1 - 1.9e-33 114.6 0.5 3.7e-33 113.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) NUC173 PF08161.12 EJP63559.1 - 1.2e-77 260.2 5.7 1.3e-76 256.8 0.5 3.6 5 0 0 5 5 5 1 NUC173 domain Vac14_Fab1_bd PF12755.7 EJP63559.1 - 0.022 15.3 0.4 25 5.6 0.0 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EJP63559.1 - 0.067 13.6 13.2 1.1 9.7 2.9 5.2 4 1 0 4 4 4 0 HEAT repeats SDA1 PF05285.12 EJP63559.1 - 0.42 10.0 21.1 0.015 14.7 14.8 1.6 1 1 0 1 1 1 0 SDA1 HEAT PF02985.22 EJP63559.1 - 3.5 8.1 7.2 17 6.0 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat Metallophos_2 PF12850.7 EJP63560.1 - 4.9e-12 46.4 0.0 6.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Shugoshin_N PF07558.11 EJP63561.1 - 2.7e-10 40.0 7.5 5.6e-10 38.9 7.5 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EJP63561.1 - 3.7e-10 39.4 7.6 3.7e-10 39.4 7.6 3.4 3 0 0 3 3 3 1 Shugoshin C terminus DUF3450 PF11932.8 EJP63561.1 - 6.1 6.1 10.2 0.043 13.1 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 EJP63561.1 - 7.4 6.6 6.3 1.6 8.7 0.4 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat M PF02370.16 EJP63561.1 - 9.6 7.2 6.4 38 5.3 0.2 3.0 2 0 0 2 2 2 0 M protein repeat DASH_Dad2 PF08654.10 EJP63562.1 - 1.4e-32 112.0 0.0 2.4e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.22 EJP63562.1 - 0.0022 18.2 0.2 0.0039 17.4 0.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.6 EJP63562.1 - 0.057 13.8 0.9 0.12 12.8 0.9 1.7 1 1 0 1 1 1 0 Snapin/Pallidin SpoOE-like PF09388.10 EJP63562.1 - 0.059 13.3 0.3 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein DUF1664 PF07889.12 EJP63562.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Haspin_kinase PF12330.8 EJP63563.1 - 0.39 9.6 2.2 0.65 8.9 2.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain SKG6 PF08693.10 EJP63564.1 - 7.1e-09 34.9 2.9 1.3e-08 34.1 2.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 EJP63564.1 - 0.048 13.1 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SKG6 PF08693.10 EJP63565.1 - 0.022 14.1 0.5 0.041 13.3 0.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HA2 PF04408.23 EJP63566.1 - 3.3e-18 66.0 0.1 8.2e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EJP63566.1 - 1.5e-12 47.7 0.0 3.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EJP63566.1 - 1.2e-11 44.9 0.0 3e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EJP63566.1 - 0.00024 21.4 0.0 0.00068 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP63566.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP63566.1 - 0.0038 17.6 0.0 0.021 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EJP63566.1 - 0.0045 16.8 0.5 0.028 14.2 0.5 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_33 PF13671.6 EJP63566.1 - 0.06 13.5 0.6 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EJP63566.1 - 0.094 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EJP63566.1 - 0.11 12.6 0.2 11 6.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain cobW PF02492.19 EJP63566.1 - 0.13 11.9 0.3 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CUE PF02845.16 EJP63567.1 - 2.9e-13 49.3 0.0 5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain Ank_2 PF12796.7 EJP63568.1 - 5.3e-27 94.2 0.8 1.7e-09 38.1 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP63568.1 - 6.8e-23 80.7 2.0 8.7e-06 26.2 0.0 5.2 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP63568.1 - 4.3e-16 57.4 1.8 0.0044 17.4 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat SPX PF03105.19 EJP63568.1 - 1.2e-15 58.3 7.6 1.9e-09 37.9 0.9 2.3 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.6 EJP63568.1 - 2.4e-15 56.4 6.1 0.0042 17.4 0.0 6.3 2 1 5 7 7 7 5 Ankyrin repeats (many copies) GDPD PF03009.17 EJP63568.1 - 3.1e-11 43.5 0.0 2.6e-10 40.5 0.0 2.3 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank PF00023.30 EJP63568.1 - 1.1e-08 35.2 11.0 0.011 16.2 0.0 6.3 5 1 1 6 6 6 3 Ankyrin repeat RVP PF00077.20 EJP63568.1 - 0.026 14.8 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease PGF-CTERM PF18204.1 EJP63569.1 - 0.018 15.0 2.8 0.018 15.0 2.8 3.2 3 0 0 3 3 3 0 PGF-CTERM motif MARVEL PF01284.23 EJP63570.1 - 0.082 12.9 0.5 0.093 12.8 0.5 1.0 1 0 0 1 1 1 0 Membrane-associating domain YtxH PF12732.7 EJP63571.1 - 0.016 15.7 1.4 0.024 15.2 1.4 1.3 1 0 0 1 1 1 0 YtxH-like protein DUF4536 PF15055.6 EJP63571.1 - 0.19 12.0 0.9 0.31 11.3 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Lipocalin PF00061.23 EJP63572.1 - 1.6e-10 41.4 0.1 1.7e-10 41.3 0.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family 2-Hacid_dh_C PF02826.19 EJP63574.1 - 6.4e-47 159.2 0.0 9.4e-47 158.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EJP63574.1 - 0.00085 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh PF00389.30 EJP63574.1 - 0.002 17.8 0.0 0.0058 16.3 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 EJP63574.1 - 0.0091 16.4 0.1 0.028 14.9 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.6 EJP63574.1 - 0.013 16.0 0.1 0.03 14.8 0.1 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain ELFV_dehydrog PF00208.21 EJP63574.1 - 0.047 13.4 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 EJP63574.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2012 PF09430.10 EJP63575.1 - 2.6e-18 66.3 0.0 4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WW PF00397.26 EJP63576.1 - 1.9e-11 43.8 2.4 3.3e-11 43.1 2.4 1.4 1 0 0 1 1 1 1 WW domain Dala_Dala_lig_C PF07478.13 EJP63577.1 - 4.2e-11 42.8 0.0 1.3e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Methyltransf_25 PF13649.6 EJP63577.1 - 5.2e-07 30.3 0.0 1.3e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP63577.1 - 3.5e-05 24.4 0.0 8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP63577.1 - 4.4e-05 24.1 0.0 0.00028 21.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ATP-grasp_4 PF13535.6 EJP63577.1 - 0.006 16.2 0.0 4 7.0 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp domain Methyltransf_23 PF13489.6 EJP63577.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATP-grasp_3 PF02655.14 EJP63577.1 - 0.017 15.1 0.0 0.52 10.4 0.0 2.6 2 1 0 2 2 2 0 ATP-grasp domain Methyltransf_31 PF13847.6 EJP63577.1 - 0.034 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATPgrasp_YheCD PF14398.6 EJP63577.1 - 0.23 10.7 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp IPPT PF01715.17 EJP63578.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 IPP transferase Peptidase_A4 PF01828.17 EJP63579.1 - 5.1e-61 205.8 7.5 6.1e-61 205.5 7.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family NTF-like PF14540.6 EJP63579.1 - 0.24 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase-like ACC_epsilon PF13822.6 EJP63579.1 - 0.25 12.1 4.1 0.48 11.1 4.1 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Choline_transpo PF04515.12 EJP63580.1 - 1.8e-29 103.0 20.1 1.8e-29 103.0 20.1 2.8 2 2 0 2 2 2 1 Plasma-membrane choline transporter Ras PF00071.22 EJP63581.1 - 5.8e-49 165.8 0.0 8.5e-38 129.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EJP63581.1 - 1e-28 100.0 0.0 4e-18 65.8 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP63581.1 - 5.4e-12 45.5 0.0 1.7e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EJP63581.1 - 9.8e-07 28.5 0.0 2.6e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EJP63581.1 - 3e-06 26.8 0.0 7.5e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJP63581.1 - 0.00018 21.5 0.0 0.00085 19.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP63581.1 - 0.00052 20.0 0.0 0.91 9.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EJP63581.1 - 0.16 12.3 0.2 0.55 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain PMT PF02366.18 EJP63582.1 - 4.9e-85 285.0 13.9 4.9e-85 285.0 13.9 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EJP63582.1 - 3.9e-67 225.7 16.8 3.9e-67 225.7 16.8 1.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EJP63582.1 - 3.2e-38 131.5 0.5 4.8e-38 130.9 0.5 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 EJP63582.1 - 2.4 8.0 10.6 0.079 12.8 1.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) zinc_ribbon_6 PF14599.6 EJP63583.1 - 4.3e-24 84.3 0.2 4.3e-24 84.3 0.2 4.2 3 1 1 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 EJP63583.1 - 3.6e-20 72.2 23.1 3.6e-20 72.2 23.1 3.6 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EJP63583.1 - 9.4e-08 32.3 10.2 9.4e-08 32.3 10.2 5.4 3 2 3 6 6 6 1 Ring finger domain zf-RING_5 PF14634.6 EJP63583.1 - 1e-06 28.6 7.1 1e-06 28.6 7.1 6.0 2 1 3 5 5 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EJP63583.1 - 1.1e-05 25.2 8.0 1.1e-05 25.2 8.0 5.9 2 1 4 6 6 6 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJP63583.1 - 2.2e-05 24.2 8.2 2.2e-05 24.2 8.2 5.1 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJP63583.1 - 0.026 14.3 1.9 0.026 14.3 1.9 4.5 4 0 0 4 4 4 0 RING-like zinc finger MOZART1 PF12554.8 EJP63584.1 - 2.7e-25 87.9 0.7 2.7e-25 87.9 0.7 1.4 2 0 0 2 2 2 1 Mitotic-spindle organizing gamma-tubulin ring associated RNaseH_pPIWI_RE PF13032.6 EJP63584.1 - 0.0084 16.0 0.1 0.0084 16.0 0.1 1.1 1 0 0 1 1 1 1 RNaseH domain of pPIWI_RE RUN PF02759.19 EJP63584.1 - 0.093 12.7 0.3 0.12 12.4 0.3 1.0 1 0 0 1 1 1 0 RUN domain Spindle_Spc25 PF08234.12 EJP63585.1 - 6e-24 84.1 0.0 1.2e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 MAP2_projctn PF08377.10 EJP63585.1 - 0.019 13.0 1.4 0.023 12.8 1.4 1.1 1 0 0 1 1 1 0 MAP2/Tau projection domain DLH PF01738.18 EJP63585.1 - 0.14 11.7 1.8 0.21 11.1 1.1 1.6 1 1 1 2 2 2 0 Dienelactone hydrolase family Atg14 PF10186.9 EJP63585.1 - 0.32 10.1 8.1 0.45 9.5 8.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 EJP63585.1 - 0.48 9.7 6.7 0.7 9.2 6.7 1.3 1 0 0 1 1 1 0 FAM76 protein AAA_23 PF13476.6 EJP63585.1 - 0.83 10.1 5.7 1.6 9.2 5.7 1.4 1 0 0 1 1 1 0 AAA domain DUF503 PF04456.12 EJP63585.1 - 1.6 8.6 5.6 0.88 9.5 0.1 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF503) DUF1664 PF07889.12 EJP63585.1 - 7.3 6.6 7.6 19 5.3 1.9 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EJP63585.1 - 8.7 5.6 12.8 13 5.1 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rrn6 PF10214.9 EJP63586.1 - 2.5e-154 515.9 0.0 3.1e-154 515.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor PITH PF06201.13 EJP63587.1 - 1.9e-41 141.8 0.0 2.3e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_L3 PF00297.22 EJP63588.1 - 2.2e-15 56.5 2.5 8.3e-13 48.0 1.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 EJP63589.1 - 2.8e-41 139.9 0.0 4e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Mito_carr PF00153.27 EJP63591.1 - 1.3e-27 95.6 5.6 2.2e-12 46.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 EJP63592.1 - 6.3e-06 26.8 7.4 1.2 10.1 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 EJP63592.1 - 0.024 13.3 0.0 12 4.4 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 SGL PF08450.12 EJP63593.1 - 1.1e-05 25.1 0.2 0.003 17.2 0.0 2.7 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region GSDH PF07995.11 EJP63593.1 - 0.0044 16.4 0.3 0.058 12.7 0.2 2.4 1 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 EJP63593.1 - 0.029 14.4 2.2 1.3 9.2 0.0 4.3 6 0 0 6 6 6 0 NHL repeat RCC1_2 PF13540.6 EJP63593.1 - 0.064 13.1 1.5 7.7 6.4 0.3 3.0 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat PD40 PF07676.12 EJP63593.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat AMP-binding PF00501.28 EJP63594.1 - 1.8e-79 267.4 0.0 2.3e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.23 EJP63595.1 - 2.1e-11 44.0 9.3 2.7e-11 43.7 9.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.20 EJP63596.1 - 5.4e-150 499.2 0.0 6.1e-150 499.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EJP63596.1 - 2.6e-09 36.7 0.0 3.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EJP63596.1 - 4.8e-09 36.0 0.0 7.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EJP63596.1 - 1e-07 31.2 0.3 1.7e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EJP63596.1 - 5.4e-06 25.9 0.0 9.1e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EJP63596.1 - 0.0018 16.9 0.0 0.0025 16.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 EJP63596.1 - 0.027 14.7 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Dynactin_p22 PF07426.11 EJP63596.1 - 0.12 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 SepSecS PF05889.13 EJP63596.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Sigma_reg_N PF13800.6 EJP63597.1 - 0.0069 16.7 0.5 2.5 8.5 0.0 3.4 3 0 0 3 3 3 2 Sigma factor regulator N-terminal SDA1 PF05285.12 EJP63598.1 - 5.5e-79 266.1 32.8 5.5e-79 266.1 32.8 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EJP63598.1 - 1e-19 70.6 0.8 1.9e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 NUC130/3NT domain MFS_1 PF07690.16 EJP63599.1 - 5.4e-20 71.6 33.1 9.5e-20 70.8 25.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP63599.1 - 2.6e-06 26.6 8.2 2.6e-06 26.6 8.2 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter Ferritin_2 PF13668.6 EJP63600.1 - 5e-16 59.1 0.0 7.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Trypsin PF00089.26 EJP63604.1 - 2.1e-39 135.6 0.2 3.1e-39 135.1 0.2 1.2 1 0 0 1 1 1 1 Trypsin Mito_carr PF00153.27 EJP63605.1 - 1.3e-43 146.8 8.5 4.8e-17 61.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_zinc_N PF00107.26 EJP63607.1 - 2.3e-21 76.1 0.0 4.1e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP63607.1 - 5.8e-19 68.0 3.5 9e-19 67.4 3.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EJP63607.1 - 8.3e-07 30.1 0.0 1.6e-06 29.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EJP63607.1 - 0.00031 20.1 0.2 0.0014 17.9 0.1 1.9 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EJP63607.1 - 0.029 13.7 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Vhr1 PF04001.13 EJP63607.1 - 0.15 12.3 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Transcription factor Vhr1 Ank_4 PF13637.6 EJP63609.1 - 5.9e-15 55.4 0.6 6.2e-05 23.5 0.0 5.8 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EJP63609.1 - 2.1e-12 46.9 0.4 0.00014 22.2 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EJP63609.1 - 4.1e-12 46.5 0.0 3.5e-07 30.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP63609.1 - 1.8e-09 37.0 0.2 0.001 19.4 0.0 5.1 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EJP63609.1 - 1.2e-08 35.1 5.9 9.4e-06 25.8 0.3 4.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) EthD PF07110.11 EJP63610.1 - 0.066 14.4 0.8 6.9 7.9 0.5 3.3 2 1 1 3 3 3 0 EthD domain RdRP PF05183.12 EJP63611.1 - 2.6e-185 617.5 0.0 4.4e-185 616.7 0.0 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF2722 PF10846.8 EJP63611.1 - 0.00032 19.8 7.8 0.00047 19.2 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 EJP63611.1 - 0.0025 17.5 12.7 0.0047 16.6 12.7 1.3 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 EJP63611.1 - 0.015 15.3 12.6 0.024 14.6 12.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 EJP63611.1 - 0.24 11.3 5.4 0.44 10.5 5.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Androgen_recep PF02166.16 EJP63611.1 - 0.28 10.0 11.3 0.48 9.2 11.3 1.3 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 EJP63611.1 - 5 5.8 5.0 7.7 5.2 5.0 1.1 1 0 0 1 1 1 0 Presenilin RskA PF10099.9 EJP63611.1 - 6.6 7.0 10.3 3.7 7.8 7.8 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA F-box PF00646.33 EJP63612.1 - 5.7e-06 26.1 0.4 1.6e-05 24.6 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EJP63612.1 - 5.5e-05 23.0 0.2 0.00021 21.1 0.5 1.9 2 0 0 2 2 2 1 F-box-like DUF2207 PF09972.9 EJP63612.1 - 0.45 9.2 0.9 0.67 8.7 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-CCHC_2 PF13696.6 EJP63612.1 - 8.2 6.4 7.1 16 5.4 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle Glyco_hydro_20 PF00728.22 EJP63613.1 - 7.7e-105 351.1 0.0 9.1e-105 350.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 EJP63613.1 - 1.7e-12 48.2 0.0 2.5e-09 38.0 0.0 3.2 2 1 1 3 3 3 2 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 EJP63613.1 - 0.17 12.5 0.1 0.48 11.1 0.0 1.7 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like ATG27 PF09451.10 EJP63614.1 - 1.6e-100 336.4 0.0 1.8e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EJP63614.1 - 3.5e-05 23.9 1.5 0.024 14.7 0.0 3.0 3 1 1 4 4 4 2 Cation-independent mannose-6-phosphate receptor repeat GRIN_C PF15235.6 EJP63614.1 - 0.044 14.0 1.5 0.075 13.3 1.5 1.4 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus DUF1115 PF06544.12 EJP63614.1 - 0.63 10.1 3.9 1.1 9.4 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) LRR_6 PF13516.6 EJP63617.1 - 1.6e-05 24.5 7.5 0.00092 19.1 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 EJP63617.1 - 0.00068 19.3 9.9 0.11 12.3 0.1 5.4 5 1 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 EJP63617.1 - 0.01 16.3 8.4 36 5.0 0.2 6.0 4 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EJP63617.1 - 0.45 11.2 7.3 17 6.4 0.2 5.5 5 1 1 6 6 6 0 Leucine Rich Repeat zf-C2H2 PF00096.26 EJP63618.1 - 0.0022 18.4 24.9 0.011 16.1 7.4 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP63618.1 - 0.0061 17.3 15.5 0.13 13.1 0.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EJP63618.1 - 0.012 16.0 1.4 0.012 16.0 1.4 3.9 4 0 0 4 4 4 0 Zinc-finger double domain FOXP-CC PF16159.5 EJP63618.1 - 0.1 13.3 1.7 0.26 11.9 1.7 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain Hexapep PF00132.24 EJP63619.1 - 2.5e-06 27.0 2.4 0.023 14.4 0.5 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EJP63619.1 - 0.0003 21.2 0.0 0.00082 19.8 0.0 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 EJP63619.1 - 0.0004 18.7 0.1 0.00061 18.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EJP63619.1 - 0.00055 19.0 1.2 0.0055 15.7 1.2 2.0 1 1 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 EJP63619.1 - 0.0086 15.7 0.0 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.6 EJP63619.1 - 0.95 9.3 6.8 13 5.7 0.1 3.3 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Spt20 PF12090.8 EJP63621.1 - 2.4e-51 174.6 0.1 2.4e-51 174.6 0.1 7.0 3 2 2 5 5 5 1 Spt20 family Caldesmon PF02029.15 EJP63621.1 - 5.5e-06 25.4 5.6 5.5e-06 25.4 5.6 3.2 2 1 1 3 3 3 1 Caldesmon AMP-binding PF00501.28 EJP63622.1 - 1.4e-128 429.1 0.0 6.5e-67 226.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EJP63622.1 - 6.4e-82 275.7 0.0 3.7e-27 95.1 0.0 5.9 4 1 1 5 5 5 4 Condensation domain PP-binding PF00550.25 EJP63622.1 - 1.5e-36 124.6 0.3 8.7e-11 42.0 0.0 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP63622.1 - 3.3e-11 44.0 0.0 0.00071 20.5 0.0 3.6 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EJP63623.1 - 1.4e-16 60.4 40.4 1.6e-11 43.8 20.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Lyase_aromatic PF00221.19 EJP63624.1 - 4.7e-147 490.4 5.8 6.6e-147 489.9 5.8 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase Shikimate_dh_N PF08501.11 EJP63624.1 - 0.063 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain ABC_tran PF00005.27 EJP63625.1 - 7.4e-32 110.7 0.0 1.4e-20 74.2 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP63625.1 - 7e-23 81.7 32.8 9.7e-21 74.6 11.6 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP63625.1 - 2e-10 40.5 0.5 5.2e-05 22.8 0.0 3.2 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EJP63625.1 - 0.0004 19.5 0.0 0.00095 18.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SbcCD_C PF13558.6 EJP63625.1 - 0.0012 19.0 0.4 0.49 10.7 0.4 3.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EJP63625.1 - 0.0013 18.6 0.0 2.8 7.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP63625.1 - 0.0085 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP63625.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EJP63625.1 - 0.023 15.0 0.1 0.074 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EJP63625.1 - 0.058 12.2 0.1 0.25 10.1 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PepSY_TM PF03929.16 EJP63625.1 - 0.06 13.0 0.0 0.25 11.0 0.0 2.1 1 0 0 1 1 1 0 PepSY-associated TM region AAA_23 PF13476.6 EJP63625.1 - 0.12 12.9 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EJP63625.1 - 0.12 13.0 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 EJP63625.1 - 0.14 11.0 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 EJP63625.1 - 0.16 12.0 0.1 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase 7tm_1 PF00001.21 EJP63625.1 - 5.2 6.3 7.2 0.23 10.7 0.6 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Aminotran_3 PF00202.21 EJP63626.1 - 2.6e-108 362.3 0.0 3.5e-108 361.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EJP63626.1 - 0.00043 19.6 0.0 0.00061 19.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 EJP63627.1 - 3.2e-72 243.3 0.0 4.5e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EJP63627.1 - 6.5e-07 28.6 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EJP63627.1 - 0.022 14.1 0.2 0.039 13.3 0.2 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sugar_tr PF00083.24 EJP63628.1 - 8e-111 371.1 24.2 9.3e-111 370.9 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP63628.1 - 8.3e-22 77.6 41.3 9.8e-22 77.3 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 EJP63629.1 - 1.4e-85 282.0 0.1 1.6e-17 63.9 0.0 8.4 1 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP63629.1 - 9.1e-64 203.9 0.2 0.00066 19.9 0.0 16.2 17 0 0 17 17 17 12 Ankyrin repeat Ank_4 PF13637.6 EJP63629.1 - 4.1e-63 209.0 1.0 2.2e-11 44.0 0.0 10.0 6 4 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP63629.1 - 1.2e-55 184.8 9.9 1e-09 38.5 0.0 13.0 2 2 11 15 15 15 11 Ankyrin repeats (many copies) Ank PF00023.30 EJP63629.1 - 1.5e-54 180.1 12.6 0.00014 22.1 0.0 15.0 15 1 0 15 15 15 10 Ankyrin repeat Ribosomal_S6 PF01250.17 EJP63629.1 - 0.014 15.7 0.0 16 5.8 0.0 3.9 4 1 0 4 4 4 0 Ribosomal protein S6 DUF2384 PF09722.10 EJP63629.1 - 0.044 13.8 0.0 4.5 7.4 0.0 4.1 6 0 0 6 6 6 0 Protein of unknown function (DUF2384) 3HCDH_RFF PF18321.1 EJP63629.1 - 9.4 6.8 14.6 7.4 7.1 1.5 5.3 5 1 0 5 5 5 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain NYN PF01936.18 EJP63630.1 - 9.9e-33 113.7 0.0 1.4e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 EJP63630.1 - 1.2e-12 47.5 0.0 7.8e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 OST-HTH/LOTUS domain Exo_endo_phos PF03372.23 EJP63631.1 - 8.7e-08 32.0 0.2 7.9e-07 28.8 0.1 2.6 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EJP63631.1 - 0.16 11.8 0.1 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Zn_clus PF00172.18 EJP63632.1 - 1.7e-06 28.1 9.2 3.2e-06 27.1 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactonase PF10282.9 EJP63633.1 - 0.092 12.0 0.0 0.76 9.0 0.0 2.0 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Fungal_lectin PF07938.12 EJP63634.1 - 0.00036 20.0 0.3 0.00061 19.3 0.3 1.6 1 1 0 1 1 1 1 Fungal fucose-specific lectin Endotoxin_C PF03944.14 EJP63634.1 - 0.052 13.9 0.0 0.096 13.0 0.0 1.5 1 1 0 1 1 1 0 delta endotoxin NMO PF03060.15 EJP63636.1 - 2.2e-28 99.6 11.1 8.6e-27 94.4 11.0 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EJP63636.1 - 5.2e-07 29.0 2.2 1.5e-06 27.4 0.4 2.2 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EJP63636.1 - 0.0031 16.7 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 EJP63636.1 - 0.0067 15.5 5.1 0.01 14.9 5.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ALG11_N PF15924.5 EJP63636.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 ALG11 mannosyltransferase N-terminus DUF4745 PF15923.5 EJP63636.1 - 0.15 12.0 0.0 1 9.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4745) SSF PF00474.17 EJP63637.1 - 1.8e-19 69.9 29.9 3.4e-19 69.0 29.9 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Bac_luciferase PF00296.20 EJP63638.1 - 8.8e-58 196.2 2.7 1.1e-57 195.8 2.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 EJP63638.1 - 0.0078 16.0 0.3 0.3 10.8 0.1 2.6 2 1 1 3 3 3 1 Amidohydrolase Zn_clus PF00172.18 EJP63640.1 - 9.5e-08 32.0 8.1 1.9e-07 31.1 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.15 EJP63641.1 - 7.2e-40 135.7 5.0 3.6e-39 133.5 0.5 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP63641.1 - 2e-29 102.1 6.9 2e-29 102.0 0.4 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EJP63641.1 - 3e-18 66.4 0.0 5.5e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Phosphoesterase PF04185.14 EJP63642.1 - 7.1e-80 268.9 0.7 1e-79 268.3 0.7 1.2 1 0 0 1 1 1 1 Phosphoesterase family MFS_1 PF07690.16 EJP63643.1 - 8.7e-19 67.6 54.7 2e-13 50.0 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 EJP63644.1 - 6.5e-09 35.8 6.8 1.2e-08 34.9 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP63644.1 - 2.3e-06 26.8 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UPF0253 PF06786.12 EJP63644.1 - 0.92 9.8 3.8 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) Abhydrolase_6 PF12697.7 EJP63645.1 - 6e-08 33.5 2.0 7.9e-08 33.2 0.3 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 EJP63645.1 - 7e-07 29.0 0.0 0.0015 18.1 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family DUF1100 PF06500.11 EJP63645.1 - 5.4e-06 25.5 0.0 7.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 EJP63645.1 - 0.00019 20.3 0.1 0.00083 18.1 0.1 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EJP63645.1 - 0.00028 20.4 0.1 0.0029 17.1 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EJP63645.1 - 0.0011 18.7 0.1 0.0023 17.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP63645.1 - 0.0047 16.2 0.0 0.033 13.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EJP63645.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Peptidase_A4 PF01828.17 EJP63647.1 - 1.9e-71 239.9 8.0 2.2e-71 239.6 8.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family Pro-kuma_activ PF09286.11 EJP63650.1 - 3.8e-34 118.0 1.3 3.3e-33 115.0 0.1 2.6 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP63650.1 - 2.3e-05 23.8 0.1 3.8e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Subtilase family p450 PF00067.22 EJP63651.1 - 1.8e-42 145.7 0.0 2.8e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S58 PF03576.14 EJP63652.1 - 5.3e-110 367.6 1.1 6.1e-110 367.4 1.1 1.0 1 0 0 1 1 1 1 Peptidase family S58 OSCP PF00213.18 EJP63652.1 - 0.055 13.6 0.1 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit adh_short_C2 PF13561.6 EJP63653.1 - 9.3e-57 192.3 0.0 1.2e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP63653.1 - 4.1e-44 150.4 0.0 5.1e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP63653.1 - 5.2e-06 26.5 0.0 1.4e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP63653.1 - 0.00055 19.5 0.0 0.0012 18.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.16 EJP63653.1 - 0.082 13.6 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Cu-oxidase_3 PF07732.15 EJP63654.1 - 1.3e-42 144.6 2.3 8.3e-40 135.5 0.6 3.5 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP63654.1 - 5.6e-25 87.7 0.8 5.6e-25 87.7 0.8 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EJP63654.1 - 6.2e-11 42.7 0.3 2.5e-09 37.4 0.0 3.0 4 0 0 4 4 4 1 Multicopper oxidase Phosphoesterase PF04185.14 EJP63655.1 - 1.1e-77 261.6 2.1 1.8e-77 260.9 2.1 1.3 1 0 0 1 1 1 1 Phosphoesterase family Fungal_trans_2 PF11951.8 EJP63656.1 - 4.2e-40 137.7 0.1 9e-40 136.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63656.1 - 1.5e-07 31.4 12.3 2.4e-07 30.7 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 EJP63657.1 - 1.8e-118 396.0 0.1 2e-118 395.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GATase PF00117.28 EJP63658.1 - 3.9e-14 52.8 0.0 5.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EJP63658.1 - 0.00038 20.4 0.0 0.00065 19.6 0.0 1.4 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 EJP63658.1 - 0.0029 17.4 0.2 0.02 14.7 0.3 2.2 2 1 0 2 2 2 1 Peptidase C26 DUF3292 PF11696.8 EJP63659.1 - 1e-248 827.0 0.1 1.3e-248 826.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Cytochrom_B562 PF07361.11 EJP63659.1 - 0.11 13.2 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b562 Malic_M PF03949.15 EJP63660.1 - 6.5e-86 287.8 0.0 8.7e-86 287.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EJP63660.1 - 6.8e-65 218.3 1.0 1.4e-64 217.2 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Caleosin PF05042.13 EJP63661.1 - 2.4e-79 265.2 0.5 3e-79 264.8 0.5 1.1 1 0 0 1 1 1 1 Caleosin related protein N2227 PF07942.12 EJP63663.1 - 4.7e-58 196.5 0.0 6.8e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 EJP63663.1 - 0.00017 22.2 0.0 0.0013 19.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP63663.1 - 0.011 15.6 0.0 0.053 13.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain TPR_20 PF14561.6 EJP63663.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Methyltransf_12 PF08242.12 EJP63663.1 - 0.079 13.7 0.0 0.25 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain EGF_2 PF07974.13 EJP63664.1 - 5e-05 23.6 8.1 0.00012 22.4 8.1 1.6 1 0 0 1 1 1 1 EGF-like domain Glyco_hydro_43 PF04616.14 EJP63664.1 - 0.0046 16.3 0.5 0.82 8.9 0.0 2.9 2 2 1 3 3 3 1 Glycosyl hydrolases family 43 EGF PF00008.27 EJP63664.1 - 0.23 11.8 3.6 0.61 10.4 3.6 1.8 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EJP63664.1 - 0.62 10.2 7.2 1.6 8.9 7.2 1.7 1 0 0 1 1 1 0 Tenascin EGF domain EB PF01683.18 EJP63664.1 - 2 8.7 7.1 0.08 13.2 1.3 1.5 2 0 0 2 2 2 0 EB module Phosphoesterase PF04185.14 EJP63665.1 - 8.2e-68 229.2 6.8 1.1e-67 228.7 6.8 1.1 1 0 0 1 1 1 1 Phosphoesterase family DsbC PF11412.8 EJP63665.1 - 0.12 12.4 0.0 5.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Disulphide bond corrector protein DsbC DEAD PF00270.29 EJP63666.1 - 1.5e-18 67.2 0.0 5.5e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP63666.1 - 5e-17 62.3 0.0 2.2e-15 57.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EJP63666.1 - 0.0012 19.5 0.1 0.003 18.2 0.1 1.7 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 EJP63666.1 - 0.0016 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_CodY PF08222.11 EJP63666.1 - 0.022 14.3 0.2 0.057 13.0 0.2 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain TrbI_Ftype PF09677.10 EJP63666.1 - 0.15 12.4 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Cu-oxidase_3 PF07732.15 EJP63667.1 - 9.3e-42 141.8 0.2 2.4e-40 137.3 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP63667.1 - 2.7e-30 104.9 5.4 1.2e-28 99.5 1.4 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EJP63667.1 - 1.2e-10 41.8 0.0 3.8e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Sugar_tr PF00083.24 EJP63668.1 - 4.3e-98 329.1 19.6 3.3e-96 322.9 19.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP63668.1 - 1.9e-15 56.7 36.4 1.8e-14 53.5 28.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily CN_hydrolase PF00795.22 EJP63669.1 - 3.6e-37 128.1 0.0 6e-37 127.4 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DPPIV_N PF00930.21 EJP63670.1 - 2.1e-102 342.5 2.7 2.9e-102 342.0 2.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EJP63670.1 - 4.8e-34 117.7 0.3 3.4e-33 114.9 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Kelch_3 PF13415.6 EJP63670.1 - 0.045 14.1 1.2 4.1 7.8 0.2 3.2 2 0 0 2 2 2 0 Galactose oxidase, central domain PD40 PF07676.12 EJP63670.1 - 0.32 11.0 3.1 5.9 6.9 0.1 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Exo_endo_phos PF03372.23 EJP63671.1 - 4e-05 23.3 0.1 0.00029 20.4 0.1 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AA_permease_2 PF13520.6 EJP63672.1 - 5.8e-63 213.2 19.9 6.6e-63 213.0 19.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP63672.1 - 7.9e-16 57.7 18.3 1e-15 57.3 18.3 1.1 1 0 0 1 1 1 1 Amino acid permease Tail_VII PF17091.5 EJP63672.1 - 0.058 13.3 1.5 0.23 11.4 1.5 2.0 1 0 0 1 1 1 0 Inovirus G7P protein CarS-like PF01864.17 EJP63672.1 - 0.2 11.6 4.6 0.39 10.7 1.3 2.4 2 1 0 2 2 2 0 CDP-archaeol synthase CwfJ_C_2 PF04676.14 EJP63673.1 - 3.4e-27 95.2 0.1 1.3e-26 93.3 0.1 2.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EJP63673.1 - 2.2e-24 85.7 0.0 3.3e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 ssDNA_TraI_N PF18272.1 EJP63673.1 - 0.004 17.1 1.8 0.0057 16.6 0.4 2.0 2 0 0 2 2 2 1 single-stranded DNA binding TraI N-terminal subdomain Inhibitor_I9 PF05922.16 EJP63673.1 - 1.9 9.2 4.3 2.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Peptidase inhibitor I9 Abhydrolase_1 PF00561.20 EJP63674.1 - 8.3e-11 42.0 0.0 4.3e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP63674.1 - 3.1e-08 34.5 3.9 3.2e-07 31.2 3.9 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP63674.1 - 1e-05 24.9 0.0 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EJP63674.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF4097 PF13349.6 EJP63675.1 - 4.7e-11 42.5 1.2 4.1e-05 23.1 0.4 3.1 2 1 0 2 2 2 2 Putative adhesin Rota_NSP3 PF01665.16 EJP63675.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Peptidase_S8 PF00082.22 EJP63676.1 - 1.3e-31 110.0 11.1 1.8e-31 109.5 11.1 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJP63677.1 - 9.7e-13 48.6 0.8 3.2e-12 46.9 0.2 2.3 2 0 0 2 2 2 1 Peptidase inhibitor I9 Staphopain_pro PF14731.6 EJP63677.1 - 0.016 15.2 0.1 0.06 13.3 0.1 2.0 1 0 0 1 1 1 0 Staphopain proregion Pet191_N PF10203.9 EJP63677.1 - 0.24 11.7 3.3 0.48 10.8 3.3 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Zip PF02535.22 EJP63677.1 - 9 5.4 6.4 1.6 7.9 2.5 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter 6PGD PF00393.19 EJP63679.1 - 4e-85 285.7 0.0 5.6e-85 285.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EJP63679.1 - 2.5e-32 112.3 0.0 4.9e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EJP63679.1 - 1.3e-07 31.4 0.0 3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EJP63679.1 - 2.4e-06 27.5 0.0 5.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EJP63679.1 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EJP63679.1 - 2.3e-05 24.9 0.3 7.7e-05 23.2 0.0 2.1 2 1 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EJP63679.1 - 7.6e-05 22.7 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 EJP63679.1 - 0.0072 16.6 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EJP63679.1 - 0.013 15.7 0.0 0.047 14.0 0.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 EJP63679.1 - 0.033 13.7 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP63679.1 - 0.035 13.6 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_23 PF13489.6 EJP63679.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PglD_N PF17836.1 EJP63679.1 - 0.15 12.7 0.2 9.3 7.0 0.0 2.5 2 0 0 2 2 2 0 PglD N-terminal domain DUF3808 PF10300.9 EJP63680.1 - 2.2e-118 396.0 0.2 3.1e-118 395.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.13 EJP63681.1 - 3e-24 84.9 14.5 4.6e-24 84.3 14.5 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.19 EJP63682.1 - 7.3e-150 499.1 0.7 8.3e-150 498.9 0.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 EJP63682.1 - 3.8e-05 23.6 0.0 0.0038 17.2 0.0 3.2 2 1 0 2 2 2 1 PA domain AlaDh_PNT_C PF01262.21 EJP63682.1 - 0.063 12.6 0.5 0.12 11.7 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CENP-K PF11802.8 EJP63683.1 - 0.01 15.5 5.9 0.023 14.3 5.9 1.6 1 0 0 1 1 1 1 Centromere-associated protein K DUF16 PF01519.16 EJP63683.1 - 0.024 15.1 10.4 0.14 12.7 8.0 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 EJP63683.1 - 0.1 12.2 9.5 0.19 11.3 8.7 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EJP63683.1 - 0.29 10.4 16.9 0.31 10.3 15.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EJP63683.1 - 0.56 9.0 20.4 0.28 10.0 16.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 EJP63683.1 - 0.68 9.1 5.7 1.2 8.3 5.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein PV-1 PF06637.11 EJP63683.1 - 0.69 8.7 15.5 0.34 9.7 10.8 1.9 1 1 1 2 2 2 0 PV-1 protein (PLVAP) Sec34 PF04136.15 EJP63683.1 - 2.4 8.0 7.2 0.45 10.4 0.9 2.4 1 1 1 2 2 2 0 Sec34-like family Nup88 PF10168.9 EJP63683.1 - 3.4 5.4 11.7 6.2 4.5 11.7 1.3 1 0 0 1 1 1 0 Nuclear pore component PikAIV_N PF18605.1 EJP63683.1 - 6.1 6.5 8.6 0.23 11.1 2.5 1.9 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HAP1_N PF04849.13 EJP63683.1 - 9.9 5.3 22.8 29 3.7 11.5 3.1 2 1 1 3 3 3 0 HAP1 N-terminal conserved region Mpv17_PMP22 PF04117.12 EJP63686.1 - 2e-21 76.0 0.2 4.3e-21 74.9 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Glyco_hydro_25 PF01183.20 EJP63687.1 - 1.1e-39 136.4 1.0 1.4e-39 136.2 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Asp PF00026.23 EJP63688.1 - 7.2e-68 229.3 0.1 9.3e-68 229.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP63688.1 - 5.1e-15 56.1 2.1 9e-10 39.1 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP63688.1 - 6.9e-05 23.4 0.6 0.021 15.5 0.2 3.1 2 1 0 2 2 2 2 Aspartyl protease Zn_clus PF00172.18 EJP63690.1 - 3.5e-08 33.4 7.3 6.3e-08 32.6 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP63690.1 - 5.3e-06 25.7 0.0 8.6e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 EJP63691.1 - 8.1e-41 140.2 0.0 1e-26 93.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 EJP63692.1 - 1.5e-25 89.9 0.0 2e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EJP63693.1 - 1.6e-09 37.8 0.1 6.4e-09 35.9 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP63693.1 - 0.0029 17.5 0.0 0.11 12.4 0.1 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.28 EJP63694.1 - 3.1e-82 276.4 0.0 5.6e-82 275.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EJP63694.1 - 8.4e-68 228.7 0.0 1.8e-67 227.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EJP63694.1 - 9.1e-58 196.0 0.0 1.5e-57 195.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 EJP63694.1 - 2.4e-55 187.2 0.1 6.5e-54 182.6 0.0 3.2 3 0 0 3 3 2 1 KR domain PS-DH PF14765.6 EJP63694.1 - 7.1e-51 173.2 0.0 1.3e-50 172.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EJP63694.1 - 3.6e-45 154.9 0.0 9.8e-45 153.4 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP63694.1 - 5.7e-29 100.5 0.0 1.9e-28 98.9 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EJP63694.1 - 3.3e-21 75.6 0.0 8e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 EJP63694.1 - 3e-17 63.2 0.0 1.3e-16 61.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EJP63694.1 - 2.3e-16 59.9 0.1 6.8e-08 32.8 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EJP63694.1 - 3.9e-14 53.0 0.0 2e-13 50.8 0.0 2.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EJP63694.1 - 4.9e-12 46.0 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EJP63694.1 - 1.2e-10 41.2 0.6 1.3e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 EJP63694.1 - 4.4e-10 40.1 0.0 2.7e-09 37.6 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP63694.1 - 3.6e-09 36.6 0.0 2.3e-08 33.9 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP63694.1 - 2.8e-08 34.3 0.0 1.4e-07 32.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EJP63694.1 - 4.6e-08 32.9 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EJP63694.1 - 1.7e-07 30.9 0.0 0.0019 17.7 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EJP63694.1 - 3.8e-05 22.8 0.0 0.19 10.7 0.0 2.6 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 EJP63694.1 - 0.00097 18.6 0.2 0.0022 17.4 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 EJP63694.1 - 0.0042 16.9 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase ACP_syn_III PF08545.10 EJP63694.1 - 0.0097 15.7 2.0 0.091 12.6 2.0 2.5 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.15 EJP63694.1 - 0.02 14.1 0.0 5.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 EJP63694.1 - 0.047 14.7 1.9 0.076 14.0 0.0 2.5 3 0 0 3 3 1 0 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 EJP63695.1 - 5.8e-10 38.6 0.1 8.7e-10 38.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63695.1 - 3.5e-07 30.2 11.0 6.6e-07 29.3 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AbiTii PF18864.1 EJP63695.1 - 0.028 14.6 0.1 0.054 13.6 0.1 1.5 1 0 0 1 1 1 0 AbiTii SPO22 PF08631.10 EJP63695.1 - 0.082 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like MFS_1 PF07690.16 EJP63696.1 - 8.9e-27 93.9 43.8 2.4e-16 59.6 24.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 EJP63696.1 - 2.4 6.9 23.2 0.64 8.8 13.3 2.8 1 1 1 2 2 2 0 MFS_1 like family Zn_clus PF00172.18 EJP63697.1 - 3.7e-09 36.6 10.6 5.7e-09 35.9 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP63698.1 - 7.4e-05 21.7 2.0 7.4e-05 21.7 2.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2547 PF10818.8 EJP63698.1 - 0.34 11.9 2.3 7.7 7.5 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Ras PF00071.22 EJP63699.1 - 1.2e-21 77.0 0.0 1.5e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP63699.1 - 0.00022 21.4 0.0 0.00049 20.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EJP63699.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2655 PF10848.8 EJP63699.1 - 0.11 12.9 0.0 10 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2655) AAA_28 PF13521.6 EJP63699.1 - 0.19 12.0 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peroxidase_2 PF01328.17 EJP63700.1 - 3.7e-20 73.3 0.0 4.6e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Glyco_hydro_16 PF00722.21 EJP63701.1 - 2e-07 30.7 0.0 3.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_synth_2 PF03142.15 EJP63702.1 - 6.6e-23 81.1 2.5 6.6e-23 81.1 2.5 2.4 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EJP63702.1 - 1.1e-16 61.4 5.6 1.1e-16 61.4 5.6 2.7 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EJP63702.1 - 4.5e-10 39.8 0.1 1.4e-09 38.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Miga PF10265.9 EJP63703.1 - 0.16 10.9 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Mitoguardin EphA2_TM PF14575.6 EJP63703.1 - 0.17 12.8 0.0 0.44 11.5 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GPI-anchored PF10342.9 EJP63704.1 - 1.4e-05 25.8 0.2 1.4e-05 25.8 0.2 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3824 PF12868.7 EJP63704.1 - 0.0011 19.7 0.1 0.0031 18.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknwon function (DUF3824) Collagen PF01391.18 EJP63704.1 - 0.006 16.3 2.4 0.006 16.3 2.4 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Penaeidin PF05927.11 EJP63704.1 - 0.089 13.6 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Penaeidin CoatB PF10389.9 EJP63704.1 - 0.33 10.8 4.5 2.6 8.0 4.5 2.4 1 1 0 1 1 1 0 Bacteriophage coat protein B MFS_1 PF07690.16 EJP63705.1 - 2.3e-39 135.3 27.4 2.3e-39 135.3 27.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0182 PF03699.13 EJP63705.1 - 0.26 9.4 3.2 0.45 8.6 3.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) adh_short_C2 PF13561.6 EJP63706.1 - 6.5e-51 173.1 0.0 8.2e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP63706.1 - 1.7e-44 151.7 0.0 2e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP63706.1 - 1.1e-10 41.7 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP63706.1 - 9.4e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EJP63706.1 - 0.0076 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EJP63707.1 - 2.6e-30 105.5 44.4 2.6e-30 105.5 44.4 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily LacAB_rpiB PF02502.18 EJP63709.1 - 1.6e-19 70.2 0.6 2e-19 69.9 0.6 1.1 1 0 0 1 1 1 1 Ribose/Galactose Isomerase F_bP_aldolase PF01116.20 EJP63710.1 - 3.9e-82 275.9 0.1 4.4e-82 275.7 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Mustang PF15682.5 EJP63710.1 - 0.19 11.8 0.0 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Fungal_trans_2 PF11951.8 EJP63711.1 - 1.9e-14 53.3 0.6 1.6e-10 40.4 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63711.1 - 1.1e-05 25.5 10.0 2.6e-05 24.2 10.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.17 EJP63712.1 - 4.5e-97 324.7 0.0 5.9e-97 324.3 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EJP63712.1 - 2.3e-34 118.8 0.2 5.6e-34 117.5 0.2 1.7 1 0 0 1 1 1 1 DAK2 domain Transposase_28 PF04195.12 EJP63713.1 - 0.11 12.7 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Putative gypsy type transposon DUF2931 PF11153.8 EJP63715.1 - 0.09 12.5 1.2 0.38 10.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2931) DUF3328 PF11807.8 EJP63715.1 - 0.13 12.0 1.7 1.8 8.3 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) DUF4006 PF13179.6 EJP63715.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF4006) Clc-like PF07062.12 EJP63715.1 - 1.7 8.0 11.3 0.6 9.5 0.6 3.1 2 2 0 2 2 2 0 Clc-like RseC_MucC PF04246.12 EJP63716.1 - 0.17 11.8 0.4 0.5 10.3 0.4 1.7 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Peptidase_S24 PF00717.23 EJP63717.1 - 8e-07 28.9 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like MAPEG PF01124.18 EJP63718.1 - 5.2e-10 39.3 1.3 6.3e-10 39.1 1.3 1.2 1 0 0 1 1 1 1 MAPEG family TPR_2 PF07719.17 EJP63719.1 - 1.6 9.0 5.0 0.92 9.8 1.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3328 PF11807.8 EJP63720.1 - 5.8e-51 173.4 4.1 7.7e-51 173.0 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Kinesin PF00225.23 EJP63721.1 - 1e-54 185.7 0.0 8.9e-54 182.6 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EJP63721.1 - 1.2e-08 35.0 0.0 2.5e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding NRBF2 PF08961.10 EJP63721.1 - 0.0086 15.7 3.0 0.11 12.1 1.2 2.4 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator Herpes_BLRF2 PF05812.12 EJP63721.1 - 0.048 13.8 2.2 0.052 13.7 0.2 2.1 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein APC_N_CC PF16689.5 EJP63721.1 - 0.093 12.8 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain JIP_LZII PF16471.5 EJP63721.1 - 4.3 7.6 6.6 3 8.1 1.7 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Crystall_4 PF17945.1 EJP63725.1 - 2.7e-86 284.2 0.0 2.6e-45 152.8 0.0 2.3 2 0 0 2 2 2 2 Beta/Gamma crystallin Trypsin PF00089.26 EJP63725.1 - 4.5e-09 36.4 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP63725.1 - 5.1e-07 30.7 0.1 9.5e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Beta-lactamase PF00144.24 EJP63726.1 - 1.5e-42 146.1 0.4 1.5e-42 146.1 0.4 1.5 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 EJP63726.1 - 0.0006 20.3 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) ADH_N PF08240.12 EJP63727.1 - 1.9e-07 31.0 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP63727.1 - 2.6e-06 27.4 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HgmA PF04209.13 EJP63728.1 - 1.2e-140 469.0 0.1 1.4e-140 468.8 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Response_reg PF00072.24 EJP63734.1 - 9.7e-19 67.6 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EJP63734.1 - 2.6e-12 47.3 0.0 5.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EJP63734.1 - 8.6e-11 41.7 0.4 3.3e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EJP63734.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5476 PF17570.2 EJP63734.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5476) DIT1_PvcA PF05141.12 EJP63735.1 - 1.2e-93 313.6 0.0 1.9e-93 312.9 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 EJP63735.1 - 2e-22 79.4 0.0 3.2e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 EJP63735.1 - 5.1e-14 51.8 0.0 8.6e-09 34.5 0.0 3.0 2 1 0 2 2 2 2 Transferase family PP-binding PF00550.25 EJP63735.1 - 1.8e-06 28.2 0.5 6.1e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site MFS_1 PF07690.16 EJP63736.1 - 1.5e-21 76.8 53.3 2.7e-15 56.1 24.1 2.7 1 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP63736.1 - 2e-05 23.2 22.4 2.8e-05 22.8 22.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BTB PF00651.31 EJP63737.1 - 8.3e-06 26.0 0.0 2.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 EJP63737.1 - 0.043 14.0 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain DUF1349 PF07081.11 EJP63738.1 - 1.3e-22 80.3 0.0 1.6e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF4430 PF14478.6 EJP63738.1 - 0.14 12.7 0.1 0.23 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Methyltransf_32 PF13679.6 EJP63739.1 - 1.6e-24 86.7 0.0 2.8e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP63739.1 - 6.9e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EJP63739.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EJP63739.1 - 0.0025 17.1 0.1 0.0085 15.4 0.0 1.8 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 EJP63739.1 - 0.0048 17.6 0.0 0.016 15.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP63739.1 - 0.051 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EJP63739.1 - 0.12 12.2 0.2 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain TFIIB PF00382.19 EJP63740.1 - 6.3e-30 103.0 1.1 4.9e-19 68.1 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EJP63740.1 - 1.6e-23 82.9 1.4 1.6e-23 82.9 1.4 3.5 4 0 0 4 4 4 2 Brf1-like TBP-binding domain Cyclin_N PF00134.23 EJP63740.1 - 0.0001 22.0 0.6 0.012 15.3 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain MFS_1 PF07690.16 EJP63741.1 - 2.6e-21 75.9 46.1 1.9e-19 69.8 29.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.21 EJP63743.1 - 4e-85 286.5 0.0 7.4e-85 285.6 0.0 1.4 1 1 0 1 1 1 1 Amidase Melibiase_2 PF16499.5 EJP63744.1 - 2.8e-47 161.2 0.0 4.2e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EJP63744.1 - 4.1e-13 49.2 0.6 4.1e-13 49.2 0.6 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Ricin_B_lectin PF00652.22 EJP63744.1 - 7.7e-08 32.6 2.7 1.2e-07 32.0 2.7 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PP2C PF00481.21 EJP63745.1 - 2.2e-34 119.3 0.0 3.5e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Metallophos PF00149.28 EJP63747.1 - 3.2e-13 50.6 0.2 6.5e-13 49.6 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP63747.1 - 4.1e-07 30.3 0.0 2.9e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Brix PF04427.18 EJP63748.1 - 8.8e-49 166.2 0.0 1.2e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Rtf2 PF04641.12 EJP63748.1 - 0.19 11.0 9.0 0.36 10.2 9.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger PPL5 PF18168.1 EJP63748.1 - 0.91 8.8 4.5 1.7 7.8 4.5 1.4 1 0 0 1 1 1 0 Prim-pol family 5 DUF1168 PF06658.12 EJP63748.1 - 1.4 8.8 17.7 3.5 7.4 17.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF4746 PF15928.5 EJP63748.1 - 1.7 8.0 7.0 2.4 7.5 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PBP_sp32 PF07222.12 EJP63748.1 - 4.9 6.5 5.5 8.7 5.7 5.5 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DEAD PF00270.29 EJP63749.1 - 2.4e-46 157.7 0.0 3.7e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP63749.1 - 2.5e-29 101.9 0.1 9e-29 100.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP63749.1 - 0.00017 21.6 0.0 0.00052 20.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Terminase_6 PF03237.15 EJP63749.1 - 0.13 11.9 0.0 0.71 9.5 0.0 2.0 2 0 0 2 2 2 0 Terminase-like family RcsF PF16358.5 EJP63749.1 - 0.15 12.2 0.2 0.39 10.8 0.2 1.6 1 0 0 1 1 1 0 RcsF lipoprotein TPR_17 PF13431.6 EJP63750.1 - 0.001 19.3 0.9 0.2 12.1 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJP63750.1 - 0.036 13.8 4.6 17 5.2 0.0 4.5 4 0 0 4 4 4 0 TPR repeat TPR_19 PF14559.6 EJP63750.1 - 0.074 13.6 4.5 3 8.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EJP63751.1 - 4.3e-151 503.4 0.0 5.4e-151 503.1 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 EJP63751.1 - 3.4e-06 27.4 0.7 0.085 13.7 0.3 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJP63751.1 - 1.2e-05 25.1 0.4 0.014 15.5 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP63751.1 - 2.1e-05 24.2 0.4 0.12 12.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP63751.1 - 2.8e-05 24.0 0.1 0.017 15.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EJP63751.1 - 0.00016 21.8 0.1 0.06 13.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP63751.1 - 0.00041 20.1 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJP63751.1 - 0.02 15.1 0.1 16 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJP63751.1 - 0.035 14.7 0.2 29 5.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EJP63751.1 - 0.054 14.0 0.1 2 9.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PGA2 PF07543.12 EJP63751.1 - 0.78 9.7 4.8 2 8.4 4.8 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 ATP_bind_1 PF03029.17 EJP63752.1 - 4.6e-71 239.4 0.0 6.1e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EJP63752.1 - 0.00049 19.2 0.0 0.18 10.8 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EJP63752.1 - 0.0015 18.6 0.0 0.026 14.6 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EJP63752.1 - 0.0021 18.3 0.0 0.0077 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EJP63752.1 - 0.0035 17.0 0.0 0.02 14.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EJP63752.1 - 0.0035 17.1 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 EJP63752.1 - 0.0038 17.0 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 EJP63752.1 - 0.0042 16.3 0.0 0.097 11.8 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 EJP63752.1 - 0.0045 16.5 0.0 0.097 12.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 EJP63752.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EJP63752.1 - 0.0062 15.8 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 EJP63752.1 - 0.0071 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 EJP63752.1 - 0.0085 15.6 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family NACHT PF05729.12 EJP63752.1 - 0.0097 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 EJP63752.1 - 0.0097 16.1 0.0 0.034 14.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain Roc PF08477.13 EJP63752.1 - 0.014 15.6 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EJP63752.1 - 0.026 14.1 0.0 0.064 12.8 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region cobW PF02492.19 EJP63752.1 - 0.032 13.8 0.1 0.33 10.5 0.1 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CLP1_P PF16575.5 EJP63752.1 - 0.086 12.6 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop KAP_NTPase PF07693.14 EJP63752.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 EJP63752.1 - 0.14 12.7 0.3 1.5 9.4 0.0 2.6 3 1 0 3 3 2 0 AAA domain Thymidylate_kin PF02223.17 EJP63752.1 - 0.15 11.8 1.0 0.68 9.6 0.0 2.3 3 0 0 3 3 3 0 Thymidylate kinase PduV-EutP PF10662.9 EJP63752.1 - 0.17 11.6 0.0 1.4 8.6 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DNA_RNApol_7kD PF03604.13 EJP63753.1 - 5.7e-11 41.9 1.4 7.6e-11 41.5 1.4 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_9 PF14369.6 EJP63753.1 - 0.0071 16.6 1.1 0.014 15.6 1.0 1.5 1 1 0 1 1 1 1 zinc-ribbon Zn-ribbon_8 PF09723.10 EJP63753.1 - 0.018 15.2 1.4 0.043 13.9 1.4 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf_Rg PF17915.1 EJP63753.1 - 0.02 14.2 0.1 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger Lar_restr_allev PF14354.6 EJP63753.1 - 0.024 15.0 1.3 0.7 10.3 0.1 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar HypA PF01155.19 EJP63753.1 - 0.036 14.1 0.1 0.036 14.1 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GFA PF04828.14 EJP63753.1 - 0.037 14.4 0.6 3.1 8.2 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme NinF PF05810.12 EJP63753.1 - 0.038 13.9 0.2 0.049 13.5 0.2 1.2 1 0 0 1 1 1 0 NinF protein DnaJ_CXXCXGXG PF00684.19 EJP63753.1 - 0.051 13.9 1.0 0.1 13.0 1.0 1.4 1 1 1 2 2 2 0 DnaJ central domain TF_Zn_Ribbon PF08271.12 EJP63753.1 - 0.062 12.8 0.5 7 6.3 0.3 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ISL3 PF14690.6 EJP63753.1 - 0.065 13.9 0.1 0.065 13.9 0.1 2.0 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF3268 PF11672.8 EJP63753.1 - 0.069 13.5 0.7 0.12 12.7 0.7 1.4 1 1 0 1 1 1 0 zinc-finger-containing domain Zn_Tnp_IS1595 PF12760.7 EJP63753.1 - 0.078 13.0 0.3 0.078 13.0 0.3 1.9 1 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF2197 PF09963.9 EJP63753.1 - 0.081 13.2 0.4 1.8 8.9 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) YacG PF03884.14 EJP63753.1 - 0.13 12.0 0.4 0.61 9.9 0.1 2.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-TFIIB PF13453.6 EJP63753.1 - 0.14 11.5 1.2 10 5.6 0.0 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger HscB_4_cys PF18256.1 EJP63753.1 - 0.2 11.5 2.9 0.35 10.7 2.9 1.4 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Zn_ribbon_SprT PF17283.2 EJP63753.1 - 0.29 11.1 2.7 2.6 8.0 2.3 2.1 1 1 1 2 2 2 0 SprT-like zinc ribbon domain HIT PF01230.23 EJP63754.1 - 2.9e-19 69.6 0.0 5e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EJP63754.1 - 4.5e-09 36.8 0.0 6.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EJP63754.1 - 0.0047 16.8 0.1 0.01 15.7 0.0 1.6 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Aldo_ket_red PF00248.21 EJP63755.1 - 1.9e-43 148.8 0.0 1.4e-41 142.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TcpQ PF10671.9 EJP63755.1 - 0.018 15.1 0.1 0.04 14.0 0.1 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Beta-lactamase PF00144.24 EJP63756.1 - 0.0041 16.4 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.18 EJP63757.1 - 6.2e-06 25.4 0.2 4e-05 22.8 0.1 2.4 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63757.1 - 0.0012 18.9 9.7 0.0032 17.5 9.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.12 EJP63757.1 - 0.46 11.1 2.7 0.46 11.1 1.1 1.7 2 0 0 2 2 2 0 Striatin family Kelch_4 PF13418.6 EJP63758.1 - 3.2e-29 100.7 2.5 7.7e-14 51.4 0.1 6.0 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EJP63758.1 - 6.8e-26 90.0 0.2 1.8e-05 24.9 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EJP63758.1 - 5.6e-16 57.9 3.3 3.8e-06 26.4 0.0 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EJP63758.1 - 7.6e-15 54.6 1.6 0.00019 21.6 0.2 6.1 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EJP63758.1 - 2.2e-10 40.3 0.1 0.061 13.3 0.0 5.1 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EJP63758.1 - 7.2e-07 28.9 8.2 0.2 11.7 0.1 5.4 6 1 0 6 6 6 4 Kelch motif AT_hook PF02178.19 EJP63759.1 - 8.3 6.7 9.3 3 8.0 4.9 2.7 2 0 0 2 2 2 0 AT hook motif RSN1_7TM PF02714.15 EJP63760.1 - 1.4e-76 257.4 11.7 2.2e-76 256.8 11.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EJP63760.1 - 2.5e-42 145.1 0.1 3.9e-42 144.4 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EJP63760.1 - 4.1e-35 120.8 1.0 4.1e-35 120.8 1.0 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport AATase PF07247.12 EJP63761.1 - 4.6e-12 45.2 0.0 4e-08 32.3 0.0 3.0 3 0 0 3 3 3 3 Alcohol acetyltransferase Condensation PF00668.20 EJP63761.1 - 1.3e-06 27.4 0.1 2.2e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.16 EJP63761.1 - 7.4e-06 25.9 1.0 1.2e-05 25.2 0.1 1.7 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF3704 PF12488.8 EJP63761.1 - 0.28 10.9 0.7 4 7.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) 4HBT_3 PF13622.6 EJP63762.1 - 1.5e-42 146.6 0.3 1.8e-42 146.3 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EJP63762.1 - 0.0042 16.9 0.1 0.0077 16.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA thioesterase DUF4482 PF14818.6 EJP63762.1 - 0.15 12.9 1.5 0.27 12.1 0.3 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) DJ-1_PfpI PF01965.24 EJP63764.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family AAA_29 PF13555.6 EJP63764.1 - 0.11 12.3 0.1 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain KinB_sensor PF16767.5 EJP63765.1 - 0.0081 16.6 0.8 0.0081 16.6 0.8 2.8 3 1 1 4 4 3 1 Sensor domain of alginate biosynthesis sensor protein KinB CENP-F_leu_zip PF10473.9 EJP63765.1 - 0.012 15.6 20.7 1.9 8.5 0.3 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 EJP63765.1 - 0.015 15.1 9.8 0.36 10.5 3.7 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 EJP63765.1 - 0.028 14.9 31.0 0.068 13.7 7.9 4.8 3 1 2 5 5 5 0 Apg6 coiled-coil region GAS PF13851.6 EJP63765.1 - 0.032 13.6 18.8 0.036 13.4 2.7 3.9 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EJP63765.1 - 0.15 11.8 19.8 19 5.0 13.5 3.7 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DASH_Dam1 PF08653.10 EJP63765.1 - 0.35 10.7 5.0 38 4.2 0.0 4.3 4 0 0 4 4 4 0 DASH complex subunit Dam1 PI3K_P85_iSH2 PF16454.5 EJP63765.1 - 0.57 9.8 11.5 0.034 13.7 2.1 3.0 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HAP1_N PF04849.13 EJP63765.1 - 0.72 9.0 20.3 0.54 9.4 12.5 3.1 1 1 2 3 3 3 0 HAP1 N-terminal conserved region Spc7 PF08317.11 EJP63765.1 - 0.77 8.6 23.6 0.046 12.6 8.0 3.0 2 1 0 3 3 3 0 Spc7 kinetochore protein BRE1 PF08647.11 EJP63765.1 - 0.88 9.7 11.9 2.5 8.2 2.9 4.1 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase Fes1 PF08609.10 EJP63765.1 - 1.7 9.6 9.3 60 4.6 0.0 4.0 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 Occludin_ELL PF07303.13 EJP63765.1 - 1.7 9.4 6.4 9.4 7.0 0.1 3.9 2 1 1 4 4 4 0 Occludin homology domain ZapB PF06005.12 EJP63765.1 - 2.7 8.5 12.7 1.8e+02 2.6 0.0 5.1 3 1 1 4 4 4 0 Cell division protein ZapB JAKMIP_CC3 PF16034.5 EJP63765.1 - 3.1 7.7 19.5 4 7.3 13.8 3.2 1 1 0 2 2 2 0 JAKMIP CC3 domain Seadorna_VP6 PF07407.11 EJP63765.1 - 7.4 5.4 6.4 5 6.0 1.0 2.6 2 1 1 3 3 3 0 Seadornavirus VP6 protein GST_N_3 PF13417.6 EJP63766.1 - 8e-16 58.2 0.0 1.7e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP63766.1 - 1.4e-14 54.2 0.0 2.7e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EJP63766.1 - 5.9e-14 52.2 0.1 1.2e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EJP63766.1 - 0.00028 21.0 0.0 0.0011 19.1 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.25 EJP63766.1 - 0.023 14.9 0.3 0.053 13.8 0.3 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Enterotoxin_a PF01375.17 EJP63767.1 - 1.8e-09 37.6 0.0 5e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain CCDC144C PF14915.6 EJP63768.1 - 0.022 13.9 6.3 0.032 13.4 6.3 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region LYRIC PF15686.5 EJP63768.1 - 0.44 10.1 6.2 0.66 9.5 6.2 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family adh_short PF00106.25 EJP63769.1 - 2.2e-20 72.9 2.2 2.7e-20 72.7 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP63769.1 - 5.7e-15 55.5 1.3 9.4e-15 54.8 1.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP63769.1 - 2.1e-05 24.5 0.3 3.4e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EJP63769.1 - 0.044 13.5 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MccV PF17508.2 EJP63769.1 - 0.45 11.1 3.0 12 6.5 0.0 3.1 3 0 0 3 3 3 0 Microcin V bacteriocin SnoaL_2 PF12680.7 EJP63770.1 - 0.011 16.3 0.1 0.013 16.1 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF2829 PF11195.8 EJP63770.1 - 0.11 12.8 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2829) NmrA PF05368.13 EJP63771.1 - 1e-10 41.6 0.0 4e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP63771.1 - 5.2e-07 29.7 0.0 1.9e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EJP63771.1 - 5.6e-05 23.3 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EJP63771.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EJP63771.1 - 0.00051 20.0 0.0 0.00086 19.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EJP63771.1 - 0.02 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 EJP63771.1 - 0.033 13.3 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PGM_PMM_II PF02879.16 EJP63771.1 - 0.05 14.2 0.0 4.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 3Beta_HSD PF01073.19 EJP63771.1 - 0.085 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family tRNA-synt_1c PF00749.21 EJP63772.1 - 4.3e-101 337.9 0.0 5.7e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EJP63772.1 - 3.2e-33 115.0 0.0 4.8e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 EJP63772.1 - 0.025 13.9 0.2 0.058 12.7 0.2 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Aldedh PF00171.22 EJP63773.1 - 4.3e-156 520.0 0.1 4.9e-156 519.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EJP63773.1 - 3.7e-05 23.3 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Zn_clus PF00172.18 EJP63774.1 - 1.2e-09 38.1 8.0 3.3e-09 36.7 8.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP63774.1 - 0.0034 16.5 0.0 0.0075 15.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pertussis_S1 PF02917.14 EJP63775.1 - 3.8e-06 26.9 0.0 6.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Pertussis toxin, subunit 1 PS-DH PF14765.6 EJP63776.1 - 2.5e-60 204.3 0.0 3.9e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EJP63776.1 - 9.9e-58 195.0 0.5 4.1e-57 193.0 0.5 2.1 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.26 EJP63776.1 - 1.1e-55 188.9 0.8 5.8e-49 167.0 0.0 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EJP63776.1 - 3.2e-45 155.0 0.0 8.1e-45 153.7 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP63776.1 - 1.8e-29 102.1 0.1 6.3e-29 100.4 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EJP63776.1 - 1.8e-20 73.5 0.0 8.3e-20 71.3 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EJP63776.1 - 1.1e-07 31.6 0.3 2.9e-07 30.2 0.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 EJP63776.1 - 0.00019 20.9 0.4 0.00058 19.3 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 EJP63776.1 - 0.0037 16.9 0.7 0.0037 16.9 0.7 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EJP63776.1 - 0.013 15.8 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site ACP_syn_III PF08545.10 EJP63776.1 - 0.087 12.7 1.1 0.35 10.7 0.6 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FMO-like PF00743.19 EJP63777.1 - 5.5e-16 58.1 0.0 8.1e-08 31.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP63777.1 - 1.6e-11 44.1 0.0 2.4e-08 33.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP63777.1 - 1.5e-08 34.7 0.0 4.5e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EJP63777.1 - 1e-07 32.1 0.0 0.0012 18.9 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EJP63777.1 - 7.7e-07 28.6 0.0 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP63777.1 - 9.3e-07 28.3 0.0 1.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EJP63777.1 - 5.1e-05 23.0 0.0 0.014 15.0 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP63777.1 - 0.00025 19.9 0.1 0.018 13.8 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.6 EJP63777.1 - 0.005 16.0 0.0 1.7 7.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 EJP63777.1 - 0.0071 15.7 0.0 0.24 10.6 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EJP63777.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Mqo PF06039.15 EJP63777.1 - 0.019 13.5 0.0 0.16 10.5 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 EJP63777.1 - 0.11 11.5 0.1 0.51 9.3 0.1 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Fungal_trans PF04082.18 EJP63778.1 - 0.016 14.2 1.7 0.03 13.4 1.7 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain PhoLip_ATPase_C PF16212.5 EJP63779.1 - 1.3e-66 224.9 16.1 1.3e-66 224.9 16.1 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EJP63779.1 - 2.5e-23 81.5 4.9 8e-23 79.9 0.6 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EJP63779.1 - 7.6e-12 45.2 0.0 6.6e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EJP63779.1 - 1.6e-11 44.1 0.1 3.5e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EJP63779.1 - 8.9e-11 42.5 0.4 5.2e-06 26.9 0.0 3.4 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EJP63779.1 - 0.036 13.8 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TFIIB PF00382.19 EJP63780.1 - 5.8e-33 112.8 0.8 4.9e-20 71.3 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EJP63780.1 - 5.3e-11 41.9 3.4 9e-11 41.1 3.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 EJP63780.1 - 0.00091 19.3 0.2 0.0026 17.8 0.1 1.7 1 1 1 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 EJP63780.1 - 0.0017 18.4 0.1 1.5 9.0 0.0 2.8 2 1 1 3 3 3 2 Cyclin, C-terminal domain Cyclin_N PF00134.23 EJP63780.1 - 0.0091 15.7 1.3 0.042 13.6 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain zf-RRN7 PF11781.8 EJP63780.1 - 0.0097 15.6 1.1 0.02 14.5 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nore1-SARAH PF16517.5 EJP63780.1 - 0.021 14.7 0.3 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain HTH_Tnp_ISL3 PF13542.6 EJP63780.1 - 0.1 12.0 0.0 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 TFIIB_C_1 PF18542.1 EJP63780.1 - 0.13 12.3 0.2 3 7.9 0.0 2.4 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 Glycos_transf_3 PF00591.21 EJP63781.1 - 4.6e-61 206.6 0.0 7.1e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EJP63781.1 - 1.8e-12 46.9 0.2 5.9e-12 45.3 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain CoA_transf_3 PF02515.17 EJP63782.1 - 6.5e-122 407.2 0.0 7.5e-122 407.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Alk_phosphatase PF00245.20 EJP63782.1 - 0.14 11.0 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Alkaline phosphatase CBM_14 PF01607.24 EJP63784.1 - 0.029 14.6 1.2 5.3 7.3 0.1 2.5 1 1 1 2 2 2 0 Chitin binding Peritrophin-A domain MspA PF09203.11 EJP63784.1 - 0.17 11.7 24.9 1.1 9.1 9.2 2.6 1 1 1 2 2 2 0 MspA OMP_b-brl PF13505.6 EJP63784.1 - 1.8 8.6 27.6 0.37 10.9 11.6 2.3 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain p6 PF17548.2 EJP63785.1 - 0.032 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Histone-like Protein p6 DUF676 PF05057.14 EJP63785.1 - 0.035 13.6 0.0 0.15 11.5 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) IMUP PF15761.5 EJP63785.1 - 0.17 12.6 2.0 0.41 11.3 2.0 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein FHA PF00498.26 EJP63786.1 - 3.7e-16 59.2 0.0 6.5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EJP63786.1 - 0.0004 20.6 0.0 0.015 15.6 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF5075 PF16825.5 EJP63787.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IGP family C-type lectin domain HNH PF01844.23 EJP63788.1 - 0.0093 16.1 1.5 0.024 14.8 1.5 1.7 1 1 0 1 1 1 1 HNH endonuclease Asn_synthase PF00733.21 EJP63789.1 - 5.3e-19 69.1 0.6 1.8e-12 47.6 2.0 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EJP63789.1 - 5e-08 32.9 0.0 7.9e-07 29.0 0.0 2.8 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EJP63789.1 - 0.0002 21.6 0.0 0.0011 19.2 0.0 2.3 3 1 0 3 3 3 1 Glutamine amidotransferase domain Hydrolase_like PF13242.6 EJP63789.1 - 0.004 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like NAD_synthase PF02540.17 EJP63789.1 - 0.17 10.9 0.0 0.57 9.3 0.0 1.8 2 0 0 2 2 2 0 NAD synthase Aldo_ket_red PF00248.21 EJP63790.1 - 2.8e-47 161.4 0.0 5.7e-45 153.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Death PF00531.22 EJP63790.1 - 0.052 13.7 0.0 3.6 7.8 0.0 2.9 3 0 0 3 3 3 0 Death domain LysM PF01476.20 EJP63790.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 LysM domain Phage_holin_3_6 PF07332.11 EJP63791.1 - 1.6 8.8 6.0 3 7.9 6.0 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Sec7 PF01369.20 EJP63792.1 - 4.9e-27 94.8 0.2 1e-26 93.7 0.0 1.5 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 EJP63792.1 - 7.2e-19 68.3 0.0 3.7e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Glyco_hydro_16 PF00722.21 EJP63793.1 - 7.9e-35 119.9 1.5 1.2e-34 119.4 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1524 PF07510.11 EJP63794.1 - 6.4e-07 29.3 0.0 7.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 EJP63794.1 - 0.076 12.9 0.0 3.5 7.6 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease Fungal_trans_2 PF11951.8 EJP63795.1 - 1.5e-07 30.6 1.5 2.5e-07 29.8 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EJP63796.1 - 5.5e-44 150.5 71.2 9.9e-39 133.2 51.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP63796.1 - 1.2e-05 24.0 13.5 1.2e-05 24.0 13.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.7 EJP63797.1 - 1.7e-15 57.3 0.0 2.1e-05 25.0 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP63797.1 - 9.2e-12 45.2 0.0 0.0033 18.0 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EJP63797.1 - 1.9e-11 43.8 0.1 0.0019 18.6 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EJP63797.1 - 1.1e-10 40.7 0.1 0.092 13.4 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EJP63797.1 - 2.2e-10 40.6 0.2 0.013 15.8 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeats (many copies) F-box PF00646.33 EJP63797.1 - 0.029 14.2 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EJP63797.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 F-box-like DUF917 PF06032.12 EJP63798.1 - 1.6e-123 412.0 0.5 2.5e-123 411.4 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EJP63798.1 - 2.7e-33 115.5 1.3 4.1e-28 98.5 0.2 3.3 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EJP63798.1 - 4.2e-31 108.0 0.3 9.1e-28 97.2 0.0 2.9 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EJP63798.1 - 3.7e-05 22.5 0.1 0.02 13.5 0.0 2.6 2 0 0 2 2 2 2 MutL protein ROK PF00480.20 EJP63798.1 - 0.00036 20.1 1.1 0.0012 18.4 0.0 2.4 3 0 0 3 3 3 1 ROK family BcrAD_BadFG PF01869.20 EJP63798.1 - 0.00048 19.7 0.6 0.1 12.0 0.0 3.3 3 1 1 4 4 4 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 EJP63798.1 - 0.00057 20.3 0.4 1 9.8 0.0 2.9 2 0 0 2 2 2 2 Cell division protein FtsA StbA PF06406.11 EJP63798.1 - 0.0013 18.1 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 StbA protein HemeBinding_Shp PF11545.8 EJP63799.1 - 0.061 13.3 0.0 1 9.3 0.0 2.0 1 1 1 2 2 2 0 Cell surface heme-binding protein Shp DIM PF08194.12 EJP63799.1 - 1.6 9.0 4.0 1.2 9.4 0.7 2.2 2 1 0 2 2 2 0 DIM protein UCH PF00443.29 EJP63800.1 - 2.7e-40 138.5 0.0 5.9e-40 137.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EJP63800.1 - 1e-11 44.5 1.6 0.0012 18.8 0.0 3.7 3 0 0 3 3 3 3 A repeated domain in UCH-protein UCH_1 PF13423.6 EJP63800.1 - 4.7e-06 26.4 2.5 0.0002 21.1 2.5 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Trypan_PARP PF05887.11 EJP63800.1 - 2.1 8.3 21.6 0.025 14.5 13.3 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ECH_1 PF00378.20 EJP63801.1 - 5.5e-38 130.7 0.1 8.3e-37 126.9 0.0 2.5 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP63801.1 - 5.6e-24 85.2 0.3 9.7e-23 81.2 0.3 2.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MOZ_SAS PF01853.18 EJP63803.1 - 2e-54 184.0 0.0 3.1e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EJP63803.1 - 8.5e-10 38.1 0.6 0.00055 19.5 0.0 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain Rpn3_C PF08375.11 EJP63804.1 - 7.1e-26 90.4 1.5 2.2e-25 88.8 1.5 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EJP63804.1 - 4.8e-21 75.3 0.6 7.9e-20 71.3 0.0 2.6 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 EJP63804.1 - 0.0063 16.6 0.1 0.024 14.7 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat p450 PF00067.22 EJP63805.1 - 1.2e-37 129.8 0.0 1.3e-26 93.4 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 DUF3989 PF13150.6 EJP63805.1 - 0.14 11.9 0.3 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) TPR_10 PF13374.6 EJP63806.1 - 3.9e-80 261.8 12.3 3.8e-12 45.7 0.0 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 EJP63806.1 - 1.1e-71 237.1 34.3 1e-14 54.5 0.1 6.9 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 EJP63806.1 - 3.9e-18 64.1 9.4 0.0075 16.2 0.0 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 EJP63806.1 - 5.5e-18 63.7 0.8 0.073 13.7 0.0 7.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP63806.1 - 9.2e-14 50.4 5.6 1.5 9.1 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EJP63806.1 - 1.3e-13 50.1 4.9 0.58 10.1 0.1 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EJP63806.1 - 4.8e-13 48.5 3.9 2.6 8.6 0.0 7.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP63806.1 - 3.5e-09 36.5 11.0 0.12 11.8 0.6 3.7 1 1 0 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 EJP63806.1 - 8.4e-09 35.9 2.4 0.13 12.9 0.3 6.4 2 1 4 6 6 6 1 Tetratricopeptide repeat NB-ARC PF00931.22 EJP63806.1 - 1.4e-07 31.0 0.0 2.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 EJP63806.1 - 2.2e-07 30.5 5.3 2.7 8.4 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP63806.1 - 1.7e-05 25.2 6.4 4.3 7.9 0.1 7.2 5 2 2 8 8 7 1 Tetratricopeptide repeat Helo_like_N PF17111.5 EJP63806.1 - 0.0001 21.7 0.3 0.00024 20.5 0.3 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins PPR PF01535.20 EJP63806.1 - 0.0012 18.9 0.2 1.5e+02 3.0 0.0 6.1 6 0 0 6 6 5 0 PPR repeat NACHT PF05729.12 EJP63806.1 - 0.0027 17.7 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF1897 PF09005.10 EJP63806.1 - 0.061 12.8 3.6 8 6.0 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) Alpha-2-MRAP_C PF06401.11 EJP63806.1 - 0.37 10.7 2.1 0.54 10.2 0.2 2.1 2 1 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Lectin_N PF03954.14 EJP63806.1 - 2.3 8.0 7.2 5.4 6.8 2.0 3.4 2 1 0 3 3 3 0 Hepatic lectin, N-terminal domain zf-RING_2 PF13639.6 EJP63807.1 - 1.2e-08 35.1 9.7 1.8e-08 34.6 9.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJP63807.1 - 1.4e-06 28.1 8.7 2e-06 27.5 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EJP63807.1 - 5.2e-06 26.6 5.6 1e-05 25.7 5.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EJP63807.1 - 9.6e-06 25.4 4.3 1.4e-05 24.8 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP63807.1 - 1.7e-05 24.6 7.2 2.5e-05 24.1 7.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP63807.1 - 0.0031 17.5 4.0 0.0058 16.6 4.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EJP63807.1 - 0.029 14.1 4.4 0.059 13.1 4.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 EJP63807.1 - 0.21 11.6 7.3 0.32 11.0 7.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain DASH_Spc34 PF08657.10 EJP63808.1 - 1.2e-48 166.2 0.3 1.2e-23 84.2 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 RPN2_C PF18004.1 EJP63808.1 - 0.31 10.9 4.7 0.57 10.1 4.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain XhlA PF10779.9 EJP63808.1 - 0.71 10.1 3.0 0.56 10.5 1.0 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Myc_N PF01056.18 EJP63808.1 - 1.8 8.4 4.2 0.3 10.9 1.2 1.4 2 0 0 2 2 2 0 Myc amino-terminal region TFIID_20kDa PF03847.13 EJP63810.1 - 3e-17 62.9 0.0 4.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Fungal_trans PF04082.18 EJP63811.1 - 1.5e-21 76.6 0.0 2.2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP63811.1 - 1.1e-07 31.8 10.3 1.9e-07 31.1 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EJP63812.1 - 6.7e-38 130.5 45.9 2.1e-31 109.1 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP63812.1 - 3.5e-11 42.7 19.0 1.6e-10 40.4 19.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EJP63812.1 - 5.1e-06 25.2 1.7 7.7e-06 24.6 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EJP63812.1 - 5.2e-05 22.7 10.8 0.00028 20.3 3.5 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Dioxygenase_C PF00775.21 EJP63813.1 - 2.4e-10 40.1 0.9 1.3e-09 37.7 0.9 2.0 1 1 0 1 1 1 1 Dioxygenase RicinB_lectin_2 PF14200.6 EJP63814.1 - 2e-10 41.2 0.1 9.7e-08 32.6 0.0 2.2 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EJP63814.1 - 6.7e-08 32.8 0.0 7.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain MFS_1 PF07690.16 EJP63816.1 - 1.9e-41 142.2 61.9 1.3e-27 96.7 29.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 EJP63817.1 - 6.4e-41 140.4 41.8 6.4e-41 140.4 41.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP63817.1 - 9.4e-10 37.9 12.0 9.4e-10 37.9 12.0 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter Inhibitor_I9 PF05922.16 EJP63818.1 - 2.5e-06 28.1 0.3 1.2e-05 25.9 0.0 2.3 3 0 0 3 3 3 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 EJP63819.1 - 6.1e-33 114.4 5.7 7.9e-33 114.0 5.7 1.1 1 0 0 1 1 1 1 Subtilase family Aspzincin_M35 PF14521.6 EJP63820.1 - 2.2e-24 86.7 1.7 3.5e-24 86.0 0.8 1.8 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EJP63820.1 - 3.8e-21 75.4 0.6 5.9e-21 74.7 0.6 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Cytomega_UL20A PF05984.12 EJP63821.1 - 0.24 11.7 0.8 0.48 10.8 0.0 1.8 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Pectate_lyase_3 PF12708.7 EJP63822.1 - 6e-75 251.8 2.3 6.8e-61 205.8 2.3 3.0 2 0 0 2 2 2 2 Pectate lyase superfamily protein Lipase_GDSL_2 PF13472.6 EJP63822.1 - 4.6e-09 36.9 0.0 8.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family End_N_terminal PF12218.8 EJP63822.1 - 7.4e-06 25.6 2.7 0.017 14.8 0.4 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Lipase_GDSL PF00657.22 EJP63822.1 - 0.00019 21.4 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 EJP63825.1 - 1.3e-11 44.1 41.7 1.2e-09 37.5 25.2 3.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF485 PF04341.12 EJP63825.1 - 3 7.8 6.9 0.58 10.1 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF485 FBPase PF00316.20 EJP63826.1 - 2.3e-19 69.6 0.0 6.7e-19 68.1 0.0 1.7 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Asparaginase PF00710.20 EJP63827.1 - 1.2e-58 197.9 0.0 1.7e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EJP63827.1 - 9e-27 93.6 0.1 1.7e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EJP63827.1 - 3.3e-14 53.2 2.2 4.3e-08 33.6 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP63827.1 - 7.2e-07 29.0 0.1 0.038 14.5 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EJP63827.1 - 2.4e-05 24.8 0.1 0.019 15.6 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EJP63827.1 - 3.3e-05 24.1 0.4 0.48 11.0 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EJP63827.1 - 0.056 13.8 0.1 2.7 8.4 0.1 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Pkinase PF00069.25 EJP63828.1 - 1.3e-62 211.6 0.0 1.5e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP63828.1 - 1.9e-27 96.2 0.0 2.6e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP63828.1 - 0.0013 18.1 0.0 0.004 16.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EJP63828.1 - 0.0044 16.0 0.0 0.0082 15.1 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Peptidase_S51 PF03575.17 EJP63828.1 - 0.0098 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 Pkinase_fungal PF17667.1 EJP63828.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase AMPKBI PF04739.15 EJP63830.1 - 1.4e-25 89.3 1.6 1.4e-25 89.3 1.6 2.7 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 EJP63830.1 - 9.8e-25 86.6 0.0 1.6e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Peptidase_M22 PF00814.25 EJP63831.1 - 1.8e-78 264.0 0.0 2.2e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family B12-binding PF02310.19 EJP63831.1 - 0.052 13.6 0.2 0.11 12.5 0.2 1.6 1 1 0 1 1 1 0 B12 binding domain Carbam_trans_N PF02543.15 EJP63831.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus EPL1 PF10513.9 EJP63832.1 - 1.2e-20 74.5 1.7 1.2e-20 74.5 1.7 2.2 2 1 0 2 2 2 1 Enhancer of polycomb-like Macoilin PF09726.9 EJP63832.1 - 1.1 7.7 9.4 1.7 7.1 9.4 1.2 1 0 0 1 1 1 0 Macoilin family EF-hand_1 PF00036.32 EJP63833.1 - 3.8e-27 91.8 12.9 1.2e-07 30.8 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EJP63833.1 - 2.7e-23 82.2 13.7 3.5e-14 53.0 1.1 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EJP63833.1 - 2.5e-20 70.6 7.8 4.9e-05 22.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EJP63833.1 - 1.7e-18 65.2 10.5 5.7e-07 28.7 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EJP63833.1 - 3.2e-13 49.3 12.6 6e-05 22.8 0.7 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EJP63833.1 - 2.2e-06 27.9 0.0 0.0053 17.1 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EJP63833.1 - 1.3e-05 25.1 7.3 0.023 14.7 0.3 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EJP63833.1 - 0.018 15.2 1.7 0.1 12.8 1.6 2.3 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_9 PF14658.6 EJP63833.1 - 0.018 15.3 0.1 0.66 10.3 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.19 EJP63835.1 - 9.2e-39 132.7 0.2 1.5e-38 132.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 EJP63836.1 - 2.1e-42 143.5 0.1 3.5e-42 142.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EJP63836.1 - 1.2e-15 57.5 0.1 3.1e-15 56.2 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EJP63836.1 - 5e-11 42.8 0.0 9.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP63836.1 - 1.3e-07 31.6 1.3 3.1e-07 30.3 0.2 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP63836.1 - 2.2e-05 24.5 0.1 8.1e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 EJP63836.1 - 0.038 14.4 0.0 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DEC-1_N PF04625.13 EJP63836.1 - 2.2 7.2 8.3 1.2 8.1 6.4 1.4 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region NIF PF03031.18 EJP63837.1 - 3.2e-20 72.5 0.0 4.8e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4551 PF15087.6 EJP63837.1 - 0.96 8.2 4.0 1.2 7.8 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF966 PF06136.13 EJP63837.1 - 1.3 8.6 6.0 1.7 8.2 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GREB1 PF15782.5 EJP63837.1 - 2.7 5.0 4.5 3.2 4.7 4.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RRP36 PF06102.12 EJP63838.1 - 1.7e-55 187.5 26.6 1.7e-55 187.5 26.6 2.1 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 ABC1 PF03109.16 EJP63839.1 - 4.3e-31 107.6 0.0 1e-30 106.4 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Es2 PF09751.9 EJP63840.1 - 1.1e-107 361.5 1.8 1.1e-107 361.5 1.8 1.4 2 0 0 2 2 2 1 Nuclear protein Es2 PPP5 PF08321.12 EJP63841.1 - 5.3e-31 106.8 0.6 1.8e-30 105.1 0.3 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 EJP63841.1 - 2.8e-30 106.4 0.1 4.3e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EJP63841.1 - 4e-16 58.1 4.5 7.2e-05 22.4 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EJP63841.1 - 5.6e-14 51.5 2.3 1.5e-06 27.8 0.5 3.4 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.17 EJP63841.1 - 2.4e-13 49.1 2.0 0.0025 17.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EJP63841.1 - 6.3e-08 32.2 0.7 0.11 12.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJP63841.1 - 7.2e-06 26.0 0.6 0.43 11.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP63841.1 - 2.2e-05 24.8 0.3 0.0044 17.5 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EJP63841.1 - 3.1e-05 24.0 0.0 0.023 14.8 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP63841.1 - 0.00031 21.3 0.4 0.81 10.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJP63841.1 - 0.0036 17.9 2.0 0.037 14.7 0.2 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP63841.1 - 0.032 14.5 0.1 2.8 8.3 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Spt4 PF06093.13 EJP63843.1 - 2.6e-33 114.0 0.1 3.2e-33 113.7 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 EJP63843.1 - 0.1 12.6 0.4 0.3 11.1 0.1 1.8 1 1 1 2 2 2 0 Coronavirus gene 5 protein Kin17_mid PF10357.9 EJP63844.1 - 1.1e-51 174.0 1.5 1.1e-51 174.0 1.5 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 EJP63844.1 - 6e-05 23.2 1.1 0.00015 22.0 1.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJP63844.1 - 0.00013 22.2 2.7 0.00027 21.2 2.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EJP63844.1 - 0.0041 17.4 0.4 0.0041 17.4 0.4 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF572 PF04502.13 EJP63845.1 - 3.8e-62 210.8 4.9 4.6e-62 210.6 4.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF951 PF06107.11 EJP63845.1 - 0.15 12.0 4.5 2 8.4 0.1 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF951) zf-ACC PF17848.1 EJP63845.1 - 0.34 11.0 1.5 23 5.2 0.1 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Acetyltransf_3 PF13302.7 EJP63846.1 - 2.3e-17 63.9 0.5 3e-17 63.6 0.5 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP63846.1 - 0.0014 18.9 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Med5 PF08689.10 EJP63847.1 - 1.9e-92 310.8 0.0 1e-90 305.1 0.0 3.1 1 1 0 1 1 1 1 Mediator complex subunit Med5 TRAP_alpha PF03896.16 EJP63848.1 - 2.3e-09 36.9 0.0 2.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SNF2_N PF00176.23 EJP63849.1 - 9.1e-65 218.7 0.2 1.7e-64 217.8 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 EJP63849.1 - 3.1e-08 33.8 10.5 5.9e-08 32.9 10.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EJP63849.1 - 4.6e-08 32.8 9.3 9.4e-08 31.8 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJP63849.1 - 8.3e-08 32.0 10.9 1.8e-07 30.8 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP63849.1 - 5e-07 29.5 10.2 1e-06 28.5 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EJP63849.1 - 5.9e-05 23.3 7.2 0.00013 22.2 7.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EJP63849.1 - 0.00012 21.9 9.0 0.0003 20.6 9.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EJP63849.1 - 0.0004 20.3 6.0 0.00047 20.1 4.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EJP63849.1 - 0.00087 19.2 9.6 0.0019 18.1 9.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 EJP63849.1 - 0.0019 18.5 0.0 0.0054 17.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_4 PF14570.6 EJP63849.1 - 0.18 11.6 6.1 0.42 10.5 6.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EJP63849.1 - 0.44 10.8 10.0 0.9 9.8 10.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EJP63849.1 - 0.54 10.3 5.4 1.1 9.4 5.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 EJP63849.1 - 1.4 9.0 4.9 3.2 7.9 4.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-P11 PF03854.14 EJP63849.1 - 3.9 7.2 7.6 12 5.6 7.6 1.8 1 1 0 1 1 1 0 P-11 zinc finger IGR PF09597.10 EJP63850.1 - 3.1e-26 91.2 0.3 5.1e-26 90.5 0.3 1.4 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.30 EJP63850.1 - 0.01 16.2 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FAD_binding_3 PF01494.19 EJP63851.1 - 1.7e-28 99.9 0.7 2.9e-27 95.8 0.7 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EJP63851.1 - 5e-11 42.4 0.3 1.5e-06 27.7 0.2 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP63851.1 - 1.8e-08 34.4 1.4 2.2e-05 24.2 1.2 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EJP63851.1 - 3.9e-07 29.3 0.9 0.014 14.3 0.0 2.8 2 1 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EJP63851.1 - 7.4e-07 29.3 0.1 1.9e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP63851.1 - 3.9e-06 27.3 0.1 0.00038 20.9 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP63851.1 - 4.8e-06 25.5 1.8 1.5e-05 23.9 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 EJP63851.1 - 2e-05 24.0 0.1 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP63851.1 - 6e-05 22.3 1.3 0.00011 21.4 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EJP63851.1 - 0.00028 20.3 0.1 0.37 10.0 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EJP63851.1 - 0.00046 19.6 1.0 0.0011 18.4 1.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP63851.1 - 0.00052 19.2 0.4 0.0025 16.9 0.4 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EJP63851.1 - 0.0032 17.4 0.7 0.49 10.4 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 EJP63851.1 - 0.0051 16.1 0.1 0.0099 15.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 EJP63851.1 - 0.018 14.9 0.4 0.055 13.3 0.4 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EJP63851.1 - 0.023 13.8 0.7 0.041 13.0 0.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EJP63851.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EJP63851.1 - 0.025 14.2 0.3 0.046 13.4 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EJP63851.1 - 0.076 13.3 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain SE PF08491.10 EJP63851.1 - 0.15 11.1 0.0 0.94 8.5 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase bZIP_2 PF07716.15 EJP63852.1 - 0.0021 18.1 8.3 0.004 17.2 8.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EJP63852.1 - 0.035 14.2 6.4 0.035 14.2 6.4 1.7 2 0 0 2 2 2 0 bZIP transcription factor SMAP PF15477.6 EJP63853.1 - 2.5e-11 44.4 4.7 2.5e-11 44.4 4.7 4.0 2 1 0 2 2 2 1 Small acidic protein family RAMP4 PF06624.12 EJP63854.1 - 7.7e-20 70.7 0.4 9.1e-20 70.5 0.4 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 BatD PF13584.6 EJP63854.1 - 0.015 14.2 0.0 0.017 13.9 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF4391 PF14335.6 EJP63855.1 - 0.014 15.2 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Mid1 PF12929.7 EJP63856.1 - 1.1e-144 482.8 3.9 1.3e-144 482.5 3.9 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EJP63856.1 - 0.00012 22.7 8.1 0.0082 16.8 3.0 2.9 2 1 0 2 2 2 2 Fz domain TB2_DP1_HVA22 PF03134.19 EJP63857.1 - 4.7e-28 96.9 8.8 7.1e-28 96.4 8.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.15 EJP63858.1 - 8.4e-28 96.8 0.0 1.9e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EJP63858.1 - 0.13 12.3 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF5558 PF17713.1 EJP63860.1 - 0.0074 16.7 0.6 0.021 15.2 0.6 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5558) AA_kinase PF00696.28 EJP63861.1 - 4.8e-37 127.8 0.7 8.5e-37 127.0 0.1 1.7 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 EJP63861.1 - 3.6e-15 55.4 0.8 8.3e-09 35.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EJP63861.1 - 2.4e-14 52.9 4.5 4.5e-10 39.2 0.2 2.8 3 0 0 3 3 3 2 ACT domain CBM_17_28 PF03424.14 EJP63861.1 - 0.055 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 17/28) Sec10 PF07393.11 EJP63862.1 - 1.3e-147 493.3 0.0 2.4e-147 492.4 0.0 1.4 1 1 1 2 2 2 1 Exocyst complex component Sec10 F-box-like PF12937.7 EJP63862.1 - 6.5e-06 25.9 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP63862.1 - 0.00053 19.8 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain Vps53_N PF04100.12 EJP63862.1 - 0.038 13.0 0.5 0.073 12.0 0.5 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal UBA PF00627.31 EJP63862.1 - 0.1 12.5 0.2 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 UBA/TS-N domain Pkinase PF00069.25 EJP63863.1 - 1.6e-61 208.0 0.0 1.9e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP63863.1 - 2.3e-33 115.6 0.0 3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP63863.1 - 0.0067 15.8 0.0 0.014 14.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Frag1 PF10277.9 EJP63864.1 - 9.4e-46 156.1 16.8 1.1e-45 155.9 16.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MIG-14_Wnt-bd PF06664.12 EJP63864.1 - 0.00014 21.2 15.4 0.00023 20.5 1.8 2.1 1 1 1 2 2 2 2 Wnt-binding factor required for Wnt secretion DUF3852 PF12963.7 EJP63864.1 - 0.064 13.6 0.8 0.064 13.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) Rft-1 PF04506.13 EJP63864.1 - 0.088 11.5 9.3 0.77 8.4 2.2 2.2 2 0 0 2 2 2 0 Rft protein TMEM173 PF15009.6 EJP63864.1 - 0.12 11.5 1.4 0.12 11.5 0.4 1.5 2 0 0 2 2 2 0 Transmembrane protein 173 DUF2070 PF09843.9 EJP63864.1 - 0.19 10.0 7.7 0.29 9.4 7.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SARAF PF06682.12 EJP63864.1 - 0.2 11.3 0.0 5.4 6.6 0.0 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis EMP70 PF02990.16 EJP63864.1 - 0.45 9.1 8.9 0.025 13.3 3.3 1.6 2 0 0 2 2 2 0 Endomembrane protein 70 DUF4131 PF13567.6 EJP63864.1 - 0.7 9.5 17.0 0.94 9.1 0.6 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Tmemb_55A PF09788.9 EJP63864.1 - 6.9 5.7 5.1 12 4.9 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A Eisosome1 PF12757.7 EJP63865.1 - 8.4e-44 148.8 14.3 8.4e-44 148.8 14.3 5.4 2 2 2 4 4 4 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 EJP63866.1 - 1e-32 114.0 0.0 1.7e-32 113.3 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EJP63866.1 - 0.00011 21.8 0.0 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 EJP63866.1 - 0.00014 21.0 0.1 0.0002 20.4 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase2 PF03162.13 EJP63866.1 - 0.00033 20.3 0.0 0.00062 19.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EJP63866.1 - 0.003 17.4 0.0 0.0069 16.2 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EJP63866.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Methyltransf_25 PF13649.6 EJP63867.1 - 3.4e-15 56.5 0.0 6.1e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP63867.1 - 4.5e-15 56.2 0.0 1.6e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP63867.1 - 3.7e-12 46.4 0.0 6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP63867.1 - 2.6e-11 44.0 0.0 5.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP63867.1 - 4.4e-08 33.1 0.0 7.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP63867.1 - 4.7e-07 29.4 0.0 6.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EJP63867.1 - 1.7e-05 25.8 0.0 4.7e-05 24.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 EJP63867.1 - 0.00084 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 EJP63867.1 - 0.0009 18.5 0.0 0.8 8.8 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Roc PF08477.13 EJP63867.1 - 0.0015 18.8 0.4 0.052 13.8 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJP63867.1 - 0.0029 17.2 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Methyltransf_8 PF05148.15 EJP63867.1 - 0.0091 15.9 0.0 0.16 11.8 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.9 EJP63867.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 EJP63867.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3298 PF11738.8 EJP63867.1 - 0.084 13.9 0.5 1.9 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) TPR_11 PF13414.6 EJP63868.1 - 4.1e-09 36.0 0.2 0.0071 16.0 0.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 EJP63868.1 - 1.4e-08 34.9 8.2 0.0017 19.0 0.6 5.9 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJP63868.1 - 6.7e-08 32.1 0.7 0.0004 20.3 0.6 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP63868.1 - 1.3e-06 28.8 8.1 0.013 16.0 0.3 4.3 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP63868.1 - 4.7e-06 26.4 0.7 0.14 12.4 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP63868.1 - 1e-05 25.1 0.7 0.00079 19.1 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP63868.1 - 7.5e-05 23.3 2.9 0.00033 21.2 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP63868.1 - 0.00021 21.5 4.2 0.25 11.7 1.7 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJP63868.1 - 0.00031 20.9 0.3 0.059 13.8 0.3 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EJP63868.1 - 0.0068 16.5 0.4 0.061 13.5 0.2 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TipAS PF07739.13 EJP63868.1 - 0.011 16.3 1.7 0.014 15.9 0.3 2.0 2 1 0 2 2 1 0 TipAS antibiotic-recognition domain Cas_DxTHG PF09455.10 EJP63868.1 - 0.019 14.6 0.6 0.1 12.1 0.2 2.0 1 1 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family TPR_20 PF14561.6 EJP63868.1 - 0.031 14.6 3.8 0.038 14.3 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP63868.1 - 0.048 13.9 0.1 0.15 12.3 0.1 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP54_N PF02881.19 EJP63868.1 - 0.07 13.4 0.8 0.26 11.6 0.6 2.0 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain TPR_7 PF13176.6 EJP63868.1 - 0.078 13.0 0.7 5 7.4 0.2 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJP63868.1 - 1.2 9.9 9.9 0.72 10.6 0.2 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat TFIIA PF03153.13 EJP63869.1 - 0.075 13.0 20.4 0.12 12.4 20.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Polyketide_cyc PF03364.20 EJP63870.1 - 1.2e-24 87.0 0.1 1.9e-24 86.3 0.1 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EJP63870.1 - 0.0015 18.8 0.6 0.0031 17.8 0.6 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Adaptin_N PF01602.20 EJP63871.1 - 2.4e-80 270.6 0.0 5.1e-80 269.5 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EJP63871.1 - 0.0027 17.8 0.0 0.049 13.7 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 EJP63871.1 - 0.024 14.7 0.2 44 4.2 0.0 3.9 4 0 0 4 4 4 0 V-ATPase subunit H DUF572 PF04502.13 EJP63871.1 - 8.6 5.9 15.3 20 4.7 15.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) RhoGAP PF00620.27 EJP63872.1 - 3.2e-14 53.0 0.7 3.1e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 EJP63872.1 - 7.6e-12 45.1 0.0 2.1e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EJP63872.1 - 2.8e-08 33.9 0.0 2.1e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Retinin_C PF04527.12 EJP63872.1 - 0.18 12.1 0.0 0.62 10.4 0.0 2.0 1 0 0 1 1 1 0 Drosophila Retinin like protein BAR PF03114.18 EJP63872.1 - 0.29 10.7 3.7 0.45 10.1 1.5 2.1 2 0 0 2 2 2 0 BAR domain Peptidase_M19 PF01244.21 EJP63873.1 - 3.5e-100 335.3 0.0 4.3e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Ribosomal_S13 PF00416.22 EJP63874.1 - 7.3e-17 62.0 0.2 1.5e-14 54.4 0.2 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.21 EJP63875.1 - 4.3e-48 163.6 0.5 5.3e-48 163.3 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trm112p PF03966.16 EJP63876.1 - 5.3e-15 55.8 0.1 7e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 EJP63876.1 - 0.091 13.3 0.3 0.16 12.5 0.3 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain ATP-synt_S1 PF05827.12 EJP63877.1 - 6.9e-06 26.0 0.2 1.2e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.9 EJP63878.1 - 1.7e-41 141.9 16.7 1.7e-41 141.9 16.7 2.5 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Tropomyosin_1 PF12718.7 EJP63879.1 - 5.7e-53 178.9 32.4 7.2e-53 178.6 32.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EJP63879.1 - 8.8e-08 31.8 31.6 6.8e-05 22.4 20.2 2.9 1 1 1 2 2 2 2 Tropomyosin ATG16 PF08614.11 EJP63879.1 - 0.00057 20.2 33.2 0.47 10.7 16.5 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) MAD PF05557.13 EJP63879.1 - 0.0021 16.5 11.8 0.0021 16.5 11.8 2.0 1 1 1 2 2 2 1 Mitotic checkpoint protein Spc7 PF08317.11 EJP63879.1 - 0.0022 16.9 33.8 0.12 11.2 19.8 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein BRE1 PF08647.11 EJP63879.1 - 0.0025 17.9 32.1 0.2 11.8 9.6 2.4 1 1 2 3 3 3 2 BRE1 E3 ubiquitin ligase DUF4200 PF13863.6 EJP63879.1 - 0.0026 18.2 33.3 0.016 15.6 16.4 2.8 1 1 0 2 2 2 1 Domain of unknown function (DUF4200) CEP63 PF17045.5 EJP63879.1 - 0.0042 17.0 25.9 0.0051 16.8 25.9 1.0 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa ADIP PF11559.8 EJP63879.1 - 0.0047 17.0 32.6 0.011 15.8 8.0 3.1 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 EJP63879.1 - 0.0055 16.0 27.4 0.06 12.6 13.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 EJP63879.1 - 0.0058 16.7 7.6 0.0058 16.7 7.6 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab5-bind PF09311.11 EJP63879.1 - 0.0077 15.7 26.3 0.051 13.0 11.1 2.1 1 1 1 2 2 2 2 Rabaptin-like protein ERM PF00769.19 EJP63879.1 - 0.0098 15.7 35.9 0.048 13.5 17.9 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Cep57_CLD_2 PF14197.6 EJP63879.1 - 0.011 15.7 32.1 1.2 9.3 1.2 4.2 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 GAS PF13851.6 EJP63879.1 - 0.012 14.9 33.1 0.2 11.0 20.1 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 EJP63879.1 - 0.013 15.7 25.3 0.034 14.4 12.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF724 PF05266.14 EJP63879.1 - 0.016 15.0 25.2 0.055 13.3 9.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 EJP63879.1 - 0.02 15.3 26.2 0.033 14.6 26.2 1.3 1 0 0 1 1 1 0 Fez1 CALCOCO1 PF07888.11 EJP63879.1 - 0.021 13.7 31.7 0.097 11.5 19.3 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Lebercilin PF15619.6 EJP63879.1 - 0.023 14.4 34.4 1.5 8.4 19.5 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Uso1_p115_C PF04871.13 EJP63879.1 - 0.024 15.0 34.6 0.13 12.6 16.2 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Taxilin PF09728.9 EJP63879.1 - 0.04 13.1 30.6 0.57 9.3 8.7 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein TACC_C PF05010.14 EJP63879.1 - 0.046 13.5 26.0 0.024 14.4 13.9 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BLOC1_2 PF10046.9 EJP63879.1 - 0.061 13.6 22.9 0.71 10.2 1.4 3.8 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SOGA PF11365.8 EJP63879.1 - 0.066 14.4 25.9 4.2 8.6 10.0 3.7 1 1 1 3 3 3 0 Protein SOGA CENP-K PF11802.8 EJP63879.1 - 0.077 12.6 22.2 0.62 9.6 22.2 2.0 1 1 0 1 1 1 0 Centromere-associated protein K Jnk-SapK_ap_N PF09744.9 EJP63879.1 - 0.082 13.1 33.0 0.036 14.3 22.1 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Laminin_II PF06009.12 EJP63879.1 - 0.088 12.8 19.3 0.15 12.1 6.7 2.5 1 1 1 2 2 2 0 Laminin Domain II ALIX_LYPXL_bnd PF13949.6 EJP63879.1 - 0.094 12.0 22.4 0.14 11.4 22.4 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV APG6_N PF17675.1 EJP63879.1 - 0.094 13.2 39.5 0.25 11.9 26.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 EJP63879.1 - 0.14 12.6 41.5 2.1 8.9 3.4 3.8 1 1 2 3 3 2 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 EJP63879.1 - 0.16 12.1 36.8 0.17 11.9 10.0 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 EJP63879.1 - 0.16 12.4 23.7 0.52 10.7 6.1 4.4 2 2 1 4 4 4 0 Flagella accessory protein C (FlaC) TANGO2 PF05742.12 EJP63879.1 - 0.18 11.8 6.0 0.31 11.0 5.9 1.6 1 1 0 1 1 1 0 Transport and Golgi organisation 2 Seryl_tRNA_N PF02403.22 EJP63879.1 - 0.19 12.0 26.8 1.3 9.3 3.0 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 EJP63879.1 - 0.21 11.6 35.4 1.2 9.2 12.1 3.5 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 EJP63879.1 - 0.22 11.3 26.1 2 8.1 9.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 EJP63879.1 - 0.22 12.1 18.8 0.34 11.5 8.1 2.6 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Phage_GP20 PF06810.11 EJP63879.1 - 0.23 11.3 29.7 1.7 8.4 12.1 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 KASH_CCD PF14662.6 EJP63879.1 - 0.26 11.1 34.1 0.28 11.0 31.4 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4686 PF15742.5 EJP63879.1 - 0.32 10.1 35.7 7.5 5.6 23.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) KLRAQ PF10205.9 EJP63879.1 - 0.33 11.2 25.7 0.39 11.0 8.8 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein T3SSipB PF16535.5 EJP63879.1 - 0.36 11.3 19.3 23 5.4 12.6 2.9 1 1 1 2 2 2 0 Type III cell invasion protein SipB Fmp27_WPPW PF10359.9 EJP63879.1 - 0.4 9.5 25.3 0.17 10.7 10.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain HrpB7 PF09486.10 EJP63879.1 - 0.4 11.0 17.5 1.2 9.5 15.5 2.1 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF2203 PF09969.9 EJP63879.1 - 0.46 11.2 18.9 1.9 9.2 5.1 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3584 PF12128.8 EJP63879.1 - 0.49 7.9 27.4 0.55 7.7 27.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CHDCT2 PF08074.11 EJP63879.1 - 0.52 10.5 11.2 0.072 13.3 5.7 1.9 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF812 PF05667.11 EJP63879.1 - 0.6 8.9 27.5 0.91 8.3 27.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 EJP63879.1 - 0.61 10.2 33.4 0.27 11.3 10.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 EJP63879.1 - 0.62 10.6 13.3 1.8 9.1 3.7 3.3 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 EJP63879.1 - 0.67 9.8 18.0 0.89 9.4 4.6 2.3 1 1 0 2 2 2 0 Sec34-like family HMMR_N PF15905.5 EJP63879.1 - 0.81 9.1 32.6 1.4 8.3 32.6 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CLZ PF16526.5 EJP63879.1 - 0.89 10.0 27.6 30 5.1 2.1 3.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-H PF05837.12 EJP63879.1 - 0.89 10.0 25.6 1.9 8.9 1.2 3.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DHR10 PF18595.1 EJP63879.1 - 0.89 9.6 37.1 0.79 9.8 22.9 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 EJP63879.1 - 0.93 9.5 16.9 1.8 8.6 3.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Alanine_zipper PF11839.8 EJP63879.1 - 0.96 9.9 13.2 7.5 7.0 3.3 3.8 1 1 3 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein Cortex-I_coil PF09304.10 EJP63879.1 - 1 9.6 23.2 5.7 7.2 5.2 3.3 1 1 1 3 3 3 0 Cortexillin I, coiled coil HAUS-augmin3 PF14932.6 EJP63879.1 - 1.1 8.8 30.6 2.7 7.5 15.2 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 CASP_C PF08172.12 EJP63879.1 - 1.2 8.4 21.9 0.14 11.5 1.1 2.4 1 1 1 2 2 2 0 CASP C terminal Prefoldin PF02996.17 EJP63879.1 - 1.3 9.0 30.4 0.93 9.4 3.8 4.0 1 1 3 4 4 4 0 Prefoldin subunit COG2 PF06148.11 EJP63879.1 - 1.3 9.1 17.5 1.6 8.8 2.5 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3287 PF11690.8 EJP63879.1 - 1.4 8.6 8.6 5 6.9 0.6 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) DUF4482 PF14818.6 EJP63879.1 - 1.5 9.7 25.4 0.39 11.6 6.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) bZIP_1 PF00170.21 EJP63879.1 - 1.6 8.8 33.1 4.4 7.5 1.5 5.2 2 2 3 5 5 5 0 bZIP transcription factor DUF4618 PF15397.6 EJP63879.1 - 1.8 7.9 26.3 6.9 6.0 2.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) TFR_dimer PF04253.15 EJP63879.1 - 1.8 8.7 15.5 0.15 12.2 1.8 3.0 1 1 2 3 3 3 0 Transferrin receptor-like dimerisation domain Surfac_D-trimer PF09006.11 EJP63879.1 - 1.9 8.5 0.0 1.9 8.5 0.0 3.0 4 0 0 4 4 2 0 Lung surfactant protein D coiled-coil trimerisation CSN5_C PF18323.1 EJP63879.1 - 1.9 9.4 15.7 5 8.1 4.8 2.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain HOOK PF05622.12 EJP63879.1 - 2 6.4 30.9 7.5 4.6 30.9 1.8 1 1 0 1 1 1 0 HOOK protein Rootletin PF15035.6 EJP63879.1 - 2.1 8.3 31.4 0.12 12.3 7.4 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Leu_zip PF15294.6 EJP63879.1 - 2.2 7.7 26.2 4.4 6.7 13.3 2.0 1 1 1 2 2 2 0 Leucine zipper Atg14 PF10186.9 EJP63879.1 - 2.5 7.1 22.3 73 2.3 22.4 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 EJP63879.1 - 2.7 8.3 29.4 3.9 7.8 2.1 4.1 1 1 4 5 5 5 0 Haemolysin XhlA SHE3 PF17078.5 EJP63879.1 - 2.8 7.6 27.8 1.1 8.9 6.1 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Mod_r PF07200.13 EJP63879.1 - 2.8 8.0 28.2 1.2 9.3 5.1 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Lectin_N PF03954.14 EJP63879.1 - 3 7.6 17.6 0.46 10.2 6.3 2.6 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Nup88 PF10168.9 EJP63879.1 - 3.6 5.3 20.8 4.5 5.0 20.8 1.1 1 0 0 1 1 1 0 Nuclear pore component MS_channel PF00924.18 EJP63879.1 - 3.8 7.0 6.0 8 6.0 5.2 1.9 1 1 1 2 2 2 0 Mechanosensitive ion channel DUF5595 PF18077.1 EJP63879.1 - 3.8 7.7 24.8 1 9.5 5.4 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF5595) Fib_alpha PF08702.10 EJP63879.1 - 3.8 7.7 19.5 3.6 7.8 5.1 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 EJP63879.1 - 3.9 7.4 24.1 1 9.3 1.3 4.5 2 2 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ax_dynein_light PF10211.9 EJP63879.1 - 3.9 7.4 33.3 12 5.7 8.3 3.5 1 1 2 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 EJP63879.1 - 4.1 7.7 23.6 1.3 9.3 3.6 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) TMPIT PF07851.13 EJP63879.1 - 4.4 6.5 21.6 3 7.0 11.7 2.1 1 1 1 2 2 2 0 TMPIT-like protein KELK PF15796.5 EJP63879.1 - 4.9 7.7 33.7 0.32 11.5 2.7 3.8 1 1 3 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase YabA PF06156.13 EJP63879.1 - 5.6 7.7 26.7 5.5 7.7 10.6 3.2 1 1 2 3 3 3 0 Initiation control protein YabA AAA_13 PF13166.6 EJP63879.1 - 5.7 5.5 25.1 1.4 7.5 8.5 2.0 1 1 1 2 2 2 0 AAA domain TRAF_BIRC3_bd PF16673.5 EJP63879.1 - 6 6.7 18.8 5.7 6.8 2.1 4.0 1 1 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain PI3K_P85_iSH2 PF16454.5 EJP63879.1 - 6.2 6.4 26.7 36 3.9 26.3 2.2 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fungal_TACC PF12709.7 EJP63879.1 - 6.3 7.3 29.6 3.9 8.0 5.9 4.0 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins LPP PF04728.13 EJP63879.1 - 7.4 7.1 13.3 37 4.8 4.0 4.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Prefoldin_2 PF01920.20 EJP63879.1 - 7.5 6.6 35.3 1.8 8.6 4.1 4.3 2 1 2 4 4 4 0 Prefoldin subunit V_ATPase_I PF01496.19 EJP63879.1 - 7.6 4.3 21.5 48 1.7 21.3 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.11 EJP63879.1 - 9.3 5.8 22.4 5.3 6.6 11.9 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 EJP63879.1 - 9.4 5.5 22.9 21 4.3 23.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) N-SET PF11764.8 EJP63881.1 - 8.7e-52 175.7 0.4 8.7e-52 175.7 0.4 3.0 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EJP63881.1 - 4.4e-26 90.3 2.1 7.9e-26 89.5 0.8 2.2 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 EJP63881.1 - 7.6e-18 65.5 0.2 7.6e-18 65.5 0.2 3.6 3 2 0 4 4 4 1 SET domain UCR_Fe-S_N PF10399.9 EJP63882.1 - 0.11 11.9 0.2 3.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF4202 PF13875.6 EJP63883.1 - 9.2e-76 253.9 1.4 1e-75 253.7 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Rnk_N PF14760.6 EJP63883.1 - 0.25 11.9 5.5 0.19 12.2 2.3 2.3 2 0 0 2 2 2 0 Rnk N-terminus Myb_DNA-binding PF00249.31 EJP63884.1 - 0.0012 19.0 0.6 0.0023 18.1 0.6 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EJP63884.1 - 0.0092 16.3 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like 14-3-3 PF00244.20 EJP63885.1 - 2.9e-09 36.8 0.1 6.9e-09 35.5 0.0 1.5 2 0 0 2 2 2 1 14-3-3 protein Sterol-sensing PF12349.8 EJP63886.1 - 1.4e-35 122.4 8.1 3.1e-35 121.3 8.1 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EJP63886.1 - 5.6e-10 38.0 4.3 8.7e-10 37.3 4.3 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 EJP63886.1 - 7.9e-05 23.4 0.2 0.0057 17.5 0.1 3.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Cupin_8 PF13621.6 EJP63888.1 - 4.1e-57 193.8 0.0 5.7e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EJP63888.1 - 3.1e-05 23.6 0.1 0.014 14.9 0.1 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Spb1_C PF07780.12 EJP63889.1 - 3.9e-83 278.3 18.3 3.9e-83 278.3 18.3 3.2 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EJP63889.1 - 6.4e-55 186.0 0.0 1.3e-54 185.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EJP63889.1 - 2.8e-52 176.8 3.0 2.8e-52 176.8 3.0 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 EJP63889.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EJP63889.1 - 0.028 14.1 0.0 0.08 12.6 0.0 1.8 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF922 PF06037.11 EJP63889.1 - 0.057 13.2 1.3 0.16 11.7 1.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Dynamin_N PF00350.23 EJP63890.1 - 8.2e-44 149.6 0.0 2.1e-43 148.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EJP63890.1 - 2.8e-14 53.0 0.5 2.2e-11 43.5 0.2 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EJP63890.1 - 8.9e-07 29.0 0.0 0.00018 21.6 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EJP63890.1 - 0.044 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EJP63890.1 - 0.15 11.7 2.1 0.2 11.3 0.1 2.1 3 0 0 3 3 3 0 AAA ATPase domain Peptidase_M4_C PF02868.15 EJP63890.1 - 0.16 11.8 0.8 3.6 7.4 0.4 2.3 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain AAA_16 PF13191.6 EJP63890.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.6 3 1 0 3 3 3 0 AAA ATPase domain Cation_efflux PF01545.21 EJP63891.1 - 6.2e-12 45.7 12.1 8.5e-12 45.2 12.1 1.1 1 0 0 1 1 1 1 Cation efflux family PIG-Y PF15159.6 EJP63892.1 - 6.7e-23 81.4 8.1 9.7e-23 80.9 8.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 EJP63892.1 - 0.1 13.1 1.6 4.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) zf-MYND PF01753.18 EJP63893.1 - 6.7e-08 32.5 18.4 1.8e-07 31.1 18.4 1.8 1 0 0 1 1 1 1 MYND finger Ebp2 PF05890.12 EJP63894.1 - 3.7e-98 328.3 15.2 3.7e-98 328.3 15.2 1.5 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 B-block_TFIIIC PF04182.12 EJP63896.1 - 1.7e-12 47.3 0.0 5.2e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC LAT PF15234.6 EJP63896.1 - 0.03 14.1 0.3 0.098 12.4 0.3 1.8 1 0 0 1 1 1 0 Linker for activation of T-cells UQ_con PF00179.26 EJP63897.1 - 1.8e-18 66.6 0.0 3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C4_ClpX PF06689.13 EJP63897.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger RWD PF05773.22 EJP63897.1 - 0.038 14.3 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 RWD domain NADH_B2 PF14813.6 EJP63898.1 - 0.0016 18.2 0.3 0.0018 18.0 0.3 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Fibrillarin PF01269.17 EJP63900.1 - 3.9e-98 327.1 0.0 4.8e-98 326.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EJP63900.1 - 7e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EJP63900.1 - 0.028 14.2 0.1 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EJP63900.1 - 0.19 11.4 0.0 0.96 9.1 0.0 1.9 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F 2-Hacid_dh_C PF02826.19 EJP63901.1 - 4.4e-50 169.5 0.0 6.9e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJP63901.1 - 1.7e-35 121.6 0.0 2.4e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EJP63901.1 - 0.00026 21.2 0.3 0.00075 19.7 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 EJP63901.1 - 0.0035 17.1 0.0 0.0079 15.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain XdhC_C PF13478.6 EJP63901.1 - 0.046 14.2 0.0 0.15 12.6 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 EJP63901.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 EJP63901.1 - 0.08 12.5 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 EJP63901.1 - 0.12 12.3 0.2 0.28 11.0 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain F-box-like PF12937.7 EJP63902.1 - 0.0046 16.8 0.3 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EJP63902.1 - 0.012 15.4 0.2 0.037 13.9 0.2 1.8 1 0 0 1 1 1 0 F-box domain DinB_2 PF12867.7 EJP63902.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 DinB superfamily DUF3455 PF11937.8 EJP63903.1 - 2.8e-42 144.8 0.0 3.9e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EJP63903.1 - 0.0014 18.8 0.3 0.016 15.4 0.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2990) CASP_C PF08172.12 EJP63904.1 - 4.5e-93 311.2 17.7 3.3e-92 308.4 0.0 3.8 4 0 0 4 4 4 1 CASP C terminal Fib_alpha PF08702.10 EJP63904.1 - 0.0064 16.7 1.8 0.0064 16.7 1.8 5.0 5 0 0 5 5 5 1 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 EJP63904.1 - 0.0092 16.0 4.2 0.0092 16.0 4.2 7.5 6 2 0 6 6 6 1 Basic region leucine zipper Rab5-bind PF09311.11 EJP63904.1 - 0.0097 15.3 0.4 0.0097 15.3 0.4 4.8 4 1 0 5 5 5 2 Rabaptin-like protein ERM PF00769.19 EJP63904.1 - 0.02 14.7 2.3 0.02 14.7 2.3 4.7 4 1 0 4 4 3 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.5 EJP63904.1 - 0.27 11.3 37.2 0.62 10.2 4.0 6.3 6 0 0 6 6 6 0 TolA binding protein trimerisation Fez1 PF06818.15 EJP63904.1 - 0.32 11.4 50.0 0.4 11.1 17.6 4.3 3 1 1 4 4 4 0 Fez1 FlaC_arch PF05377.11 EJP63904.1 - 0.41 11.1 33.8 2.2 8.8 1.0 6.7 6 1 0 6 6 6 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 EJP63904.1 - 0.85 9.7 68.9 0.49 10.4 3.7 7.0 4 2 2 6 6 6 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EJP63904.1 - 0.94 10.1 33.5 2.5 8.8 0.0 7.2 6 2 1 7 7 7 0 SlyX ZapB PF06005.12 EJP63904.1 - 2.4 8.6 54.7 0.077 13.4 1.0 6.1 3 2 1 4 4 3 0 Cell division protein ZapB SKA1 PF07160.12 EJP63904.1 - 3.9 7.3 22.3 3.4 7.4 0.2 4.5 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 1 Vps39_2 PF10367.9 EJP63905.1 - 2.3e-07 31.3 0.0 3.9e-06 27.3 0.0 2.9 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EJP63905.1 - 0.00031 21.0 0.1 0.005 17.1 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-C2H2 PF00096.26 EJP63906.1 - 6.9e-06 26.2 17.4 0.3 11.6 0.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 EJP63906.1 - 0.03 14.9 3.3 1.6 9.4 0.6 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain DUF4451 PF14616.6 EJP63906.1 - 0.035 14.3 0.9 0.085 13.1 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) zf-TAZ PF02135.16 EJP63906.1 - 0.047 14.1 2.5 0.14 12.6 1.0 2.1 2 0 0 2 2 2 0 TAZ zinc finger zf-C2H2_4 PF13894.6 EJP63906.1 - 0.054 14.4 19.4 1.2 10.2 0.3 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2HE PF16278.5 EJP63906.1 - 0.16 12.5 0.5 11 6.5 0.1 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-rbx1 PF12678.7 EJP63907.1 - 7.4e-10 39.0 3.0 1.4e-09 38.1 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EJP63907.1 - 6.6e-08 32.8 5.3 1.7e-07 31.4 5.3 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EJP63907.1 - 8.9e-06 25.6 1.0 1.8e-05 24.7 1.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EJP63907.1 - 3.9e-05 23.4 2.0 7.7e-05 22.5 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP63907.1 - 5.9e-05 22.8 5.6 0.00047 20.0 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP63907.1 - 6.6e-05 22.8 2.5 0.00021 21.2 2.5 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EJP63907.1 - 0.0012 18.7 2.1 0.0012 18.7 2.1 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EJP63907.1 - 0.0013 18.3 0.7 0.0029 17.2 0.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EJP63907.1 - 0.0017 18.2 4.3 0.0054 16.6 4.3 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EJP63907.1 - 0.0026 17.8 0.3 0.0057 16.7 0.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EJP63907.1 - 0.11 12.7 1.0 0.33 11.1 1.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EJP63907.1 - 0.23 11.3 2.6 0.35 10.7 0.9 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_transf_8 PF01501.20 EJP63908.1 - 4.2e-24 85.5 4.0 5.4e-24 85.1 0.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EJP63908.1 - 0.01 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Mito_carr PF00153.27 EJP63909.1 - 2.2e-15 56.4 10.4 5.3e-07 29.5 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein DUF2627 PF11118.8 EJP63909.1 - 0.09 13.4 0.1 0.29 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) FMO-like PF00743.19 EJP63910.1 - 5.8e-24 84.4 0.0 2.4e-14 52.7 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EJP63910.1 - 5.3e-06 25.9 0.0 0.00078 18.8 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP63910.1 - 3.2e-05 23.3 0.0 0.036 13.3 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP63910.1 - 0.0024 17.1 0.1 0.87 8.7 0.0 3.4 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EJP63910.1 - 0.02 15.1 0.0 0.088 13.1 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP63910.1 - 0.44 11.1 1.1 41 4.8 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cation_efflux PF01545.21 EJP63911.1 - 3.3e-19 69.4 8.5 4.2e-19 69.1 8.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EJP63911.1 - 3.4e-12 46.3 0.3 7.5e-12 45.2 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Hydrolase_4 PF12146.8 EJP63912.1 - 9.8e-55 185.4 0.0 1.2e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP63912.1 - 1.2e-15 57.9 0.2 6.5e-14 52.2 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP63912.1 - 3.6e-11 44.1 0.0 4.2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EJP63912.1 - 0.0039 16.7 0.1 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family ABC_membrane PF00664.23 EJP63913.1 - 2.2e-50 171.9 9.6 2.9e-50 171.5 9.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EJP63913.1 - 7.1e-33 114.0 0.2 2.5e-32 112.3 0.0 2.1 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 EJP63913.1 - 6.6e-05 22.5 0.0 0.00049 19.6 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJP63913.1 - 0.001 19.3 0.2 0.0072 16.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP63913.1 - 0.012 16.0 0.2 0.059 13.8 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EJP63913.1 - 0.018 15.4 0.1 0.29 11.5 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EJP63913.1 - 0.039 12.8 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 EJP63913.1 - 0.042 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EJP63913.1 - 0.055 13.5 0.2 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EJP63913.1 - 0.064 13.0 0.1 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 EJP63913.1 - 0.072 13.3 1.7 1.4 9.2 1.7 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EJP63913.1 - 0.1 13.2 0.7 0.43 11.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EJP63913.1 - 0.88 9.7 3.0 4.4 7.5 0.3 2.8 2 1 0 3 3 3 0 AAA domain CTD_bind PF04818.13 EJP63914.1 - 4.1e-17 62.8 0.0 1.5e-16 60.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. FliD_C PF07195.12 EJP63914.1 - 0.037 13.5 1.0 0.059 12.8 1.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF4407 PF14362.6 EJP63914.1 - 0.042 13.2 1.9 0.038 13.3 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NAM-associated PF14303.6 EJP63914.1 - 0.28 11.9 6.6 1.3 9.8 0.5 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Fur_reg_FbpB PF13040.6 EJP63914.1 - 0.85 9.2 4.0 0.84 9.2 1.9 2.0 2 0 0 2 2 2 0 Fur-regulated basic protein B Med7 PF05983.11 EJP63914.1 - 0.98 9.5 6.0 0.4 10.8 0.3 2.3 1 1 1 2 2 2 0 MED7 protein Rx_N PF18052.1 EJP63914.1 - 1 9.6 4.4 6.7 7.1 1.4 2.5 2 0 0 2 2 2 0 Rx N-terminal domain Clathrin_lg_ch PF01086.17 EJP63915.1 - 8e-73 245.3 3.9 9e-73 245.1 3.9 1.0 1 0 0 1 1 1 1 Clathrin light chain CR6_interact PF10147.9 EJP63915.1 - 0.0077 16.0 3.8 0.089 12.5 1.0 2.1 2 0 0 2 2 2 2 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 rve_3 PF13683.6 EJP63915.1 - 0.21 11.4 0.5 0.51 10.2 0.5 1.6 1 0 0 1 1 1 0 Integrase core domain DUF4407 PF14362.6 EJP63915.1 - 1.9 7.7 7.0 0.77 9.1 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) COX7a PF02238.15 EJP63916.1 - 1.4e-18 67.0 2.2 1.9e-18 66.6 2.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII DUF3662 PF12401.8 EJP63917.1 - 0.02 15.2 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) zf-CRD PF17979.1 EJP63917.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Mic1 PF07035.12 EJP63917.1 - 0.17 11.6 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like SNARE PF05739.19 EJP63918.1 - 6.2e-15 54.9 0.2 1.2e-14 54.0 0.2 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EJP63918.1 - 1.3e-05 25.0 8.1 0.0062 16.2 0.5 2.1 2 0 0 2 2 2 2 Syntaxin Rrp44_CSD1 PF17216.3 EJP63918.1 - 0.0055 16.4 0.2 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Syntaxin_2 PF14523.6 EJP63918.1 - 0.006 16.9 3.3 0.006 16.9 3.3 2.2 2 0 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.21 EJP63918.1 - 0.0063 16.3 8.9 0.16 11.8 1.0 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.6 EJP63918.1 - 0.055 14.1 5.1 0.1 13.3 0.6 2.8 2 1 0 2 2 2 0 DNA repair REX1-B Uds1 PF15456.6 EJP63918.1 - 0.11 12.7 3.6 0.088 13.0 1.1 2.1 1 1 1 2 2 2 0 Up-regulated During Septation GCP_C_terminal PF04130.13 EJP63918.1 - 0.11 12.0 2.0 0.13 11.7 1.2 1.5 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal DUF5446 PF17522.2 EJP63918.1 - 2.2 8.5 9.1 0.99 9.6 0.6 3.2 3 1 1 4 4 4 0 Family of unknown function (DUF5446) EF-hand_1 PF00036.32 EJP63919.1 - 9.7e-41 134.3 13.7 8.9e-10 37.4 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EJP63919.1 - 3.7e-36 123.4 5.5 3.5e-19 69.0 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EJP63919.1 - 6.2e-33 112.4 12.6 2.8e-15 55.9 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EJP63919.1 - 4.3e-30 101.1 8.2 2.2e-09 36.5 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EJP63919.1 - 2.4e-25 86.9 10.8 3e-06 26.5 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EJP63919.1 - 2.2e-16 59.9 0.4 2.8e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EJP63919.1 - 9.3e-09 35.2 2.3 0.0012 18.7 0.2 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EJP63919.1 - 1e-08 35.5 0.2 0.0023 18.2 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EJP63919.1 - 2.4e-06 27.5 0.0 0.0089 16.0 0.0 2.7 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EJP63919.1 - 8.7e-06 25.7 1.9 2e-05 24.6 0.3 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EJP63919.1 - 6.6e-05 23.7 0.1 0.0016 19.3 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EJP63919.1 - 8.8e-05 22.5 0.3 0.24 11.4 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 EJP63919.1 - 0.00085 19.7 0.7 0.62 10.4 0.2 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb4 Caleosin PF05042.13 EJP63919.1 - 0.0011 18.9 1.9 0.84 9.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 EJP63919.1 - 0.0079 16.4 6.9 0.44 10.8 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain SurA_N_2 PF13623.6 EJP63919.1 - 0.013 15.4 0.8 0.39 10.6 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 EJP63919.1 - 0.015 15.6 0.4 7 7.1 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain DUF5580 PF17743.1 EJP63919.1 - 0.021 13.4 0.0 0.023 13.3 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF4497 PF14924.6 EJP63919.1 - 0.035 14.6 0.0 12 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Poly_export PF02563.16 EJP63919.1 - 0.055 13.7 0.0 0.75 10.1 0.0 2.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 EJP63919.1 - 0.083 13.0 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF5132 PF17195.4 EJP63919.1 - 0.15 12.2 0.5 23 5.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Adaptin_N PF01602.20 EJP63920.1 - 1.2e-143 479.4 3.1 1.6e-143 479.0 3.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EJP63920.1 - 1.3e-24 86.6 0.3 3.1e-24 85.4 0.3 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EJP63920.1 - 2.3e-09 37.5 5.4 3e-05 24.1 0.0 4.3 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJP63920.1 - 5.3e-07 29.9 0.3 0.025 15.0 0.0 3.6 3 2 0 3 3 3 2 HEAT repeats DUF3730 PF12530.8 EJP63920.1 - 1.9e-05 24.4 0.1 0.00022 20.9 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.22 EJP63920.1 - 0.00011 22.1 0.6 2.7 8.5 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat RIX1 PF08167.12 EJP63920.1 - 0.0063 16.3 0.2 0.058 13.1 0.0 2.6 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EJP63920.1 - 0.043 14.3 0.3 40 4.9 0.0 4.1 3 1 0 3 3 3 0 HEAT-like repeat TIP120 PF08623.10 EJP63920.1 - 0.13 12.1 0.8 4.3 7.1 0.1 3.1 3 2 0 3 3 3 0 TATA-binding protein interacting (TIP20) RICTOR_M PF14666.6 EJP63920.1 - 0.15 11.8 1.1 1.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain NAD_binding_1 PF00175.21 EJP63921.1 - 4.1e-09 37.1 0.0 0.0031 18.1 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EJP63921.1 - 3e-06 27.4 0.0 0.034 14.3 0.0 2.1 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NCBP3 PF10309.9 EJP63922.1 - 2.6e-22 78.4 0.1 4.5e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 AAA_13 PF13166.6 EJP63922.1 - 0.11 11.1 0.3 0.15 10.7 0.3 1.1 1 0 0 1 1 1 0 AAA domain SRP_TPR_like PF17004.5 EJP63923.1 - 8.9e-23 80.5 2.1 4.4e-22 78.3 1.4 2.2 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 EJP63923.1 - 2.1e-16 60.1 8.2 2.1e-16 60.1 8.2 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_2 PF07719.17 EJP63923.1 - 2.9e-07 30.1 15.8 0.046 13.8 0.2 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP63923.1 - 5.2e-06 26.6 8.4 0.0012 19.0 1.1 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 EJP63923.1 - 0.00034 20.1 7.6 0.075 12.4 0.1 2.6 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 EJP63923.1 - 0.0052 17.3 25.9 1.5 9.4 0.1 6.3 4 2 2 6 6 6 2 Tetratricopeptide repeat PPR PF01535.20 EJP63923.1 - 0.0064 16.7 0.1 1.8 9.0 0.0 3.2 2 0 0 2 2 2 1 PPR repeat TPR_8 PF13181.6 EJP63923.1 - 0.0091 16.1 12.4 2.3 8.6 0.2 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat SPO22 PF08631.10 EJP63923.1 - 0.022 14.3 3.1 0.03 13.8 0.1 2.6 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_1 PF00515.28 EJP63923.1 - 0.022 14.6 10.8 0.76 9.7 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP63923.1 - 0.035 14.9 24.2 1.8 9.6 0.0 7.5 6 2 2 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 EJP63923.1 - 0.064 13.0 4.2 17 5.2 0.1 3.7 3 0 0 3 3 3 0 TPR repeat RPN7 PF10602.9 EJP63923.1 - 0.1 12.3 0.7 19 4.9 0.0 3.4 3 2 2 5 5 5 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 EJP63923.1 - 0.14 12.5 15.8 12 6.2 0.1 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EJP63923.1 - 0.78 9.7 13.2 0.6 10.1 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EJP63923.1 - 2.1 8.8 14.4 0.2 12.1 0.4 3.8 2 1 2 4 4 4 0 Bacterial transcriptional activator domain Sec7 PF01369.20 EJP63924.1 - 6.4e-32 110.7 0.5 1e-31 110.0 0.5 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EJP63924.1 - 0.00015 22.2 0.0 0.00041 20.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EJP63924.1 - 0.00063 20.1 0.1 0.0016 18.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_M14 PF00246.24 EJP63925.1 - 1.4e-71 241.7 0.0 1.8e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MAPEG PF01124.18 EJP63926.1 - 4.6e-23 81.5 0.5 5.3e-23 81.3 0.5 1.0 1 0 0 1 1 1 1 MAPEG family SMC_N PF02463.19 EJP63927.1 - 5.4e-38 130.6 14.0 1.3e-37 129.3 14.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EJP63927.1 - 1.3e-26 93.2 0.0 7.7e-26 90.7 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain DNA_pol_B_thumb PF14791.6 EJP63927.1 - 1e-21 76.8 0.1 4.7e-21 74.7 0.1 2.3 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EJP63927.1 - 1.5e-20 72.7 1.1 4.7e-20 71.1 1.1 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 EJP63927.1 - 5.4e-19 68.5 0.3 3.1e-18 66.1 0.1 2.6 2 0 0 2 2 1 1 DNA polymerase beta palm HHH_8 PF14716.6 EJP63927.1 - 2.7e-08 34.1 0.0 1.3e-06 28.6 0.0 3.7 1 1 0 1 1 1 1 Helix-hairpin-helix domain TFIIE_alpha PF02002.17 EJP63927.1 - 2.2e-07 30.7 0.1 1.3e-06 28.2 0.1 2.4 1 0 0 1 1 1 1 TFIIE alpha subunit AAA_21 PF13304.6 EJP63927.1 - 1.8e-06 28.0 0.2 2e-05 24.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ERM PF00769.19 EJP63927.1 - 0.0011 18.8 23.6 0.0011 18.8 23.6 7.2 4 3 3 7 7 5 1 Ezrin/radixin/moesin family BRCT_2 PF16589.5 EJP63927.1 - 0.0034 17.7 0.0 0.39 11.1 0.0 3.9 4 0 0 4 4 4 1 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 EJP63927.1 - 0.0057 16.9 0.0 0.04 14.2 0.0 2.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.6 EJP63927.1 - 0.021 15.4 0.0 1.2 9.8 0.0 3.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain SbcCD_C PF13558.6 EJP63927.1 - 0.035 14.4 0.0 0.17 12.2 0.0 2.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ATG16 PF08614.11 EJP63927.1 - 0.75 10.0 105.5 0.046 14.0 21.5 6.5 5 2 1 6 6 6 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EJP63927.1 - 3.6 6.4 122.1 0.048 12.5 12.6 7.9 4 2 4 8 8 8 0 Spc7 kinetochore protein DUF948 PF06103.11 EJP63927.1 - 8.5 6.7 36.6 0.031 14.5 2.3 7.6 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF948) DUF2838 PF10998.8 EJP63928.1 - 9.4e-46 154.6 10.3 9.4e-46 154.6 10.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Apolipoprotein PF01442.18 EJP63928.1 - 0.01 15.7 2.2 0.018 14.9 2.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3584 PF12128.8 EJP63928.1 - 0.24 8.9 2.8 0.31 8.5 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WD40 PF00400.32 EJP63929.1 - 5.1e-18 65.1 14.5 0.00086 20.1 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP63929.1 - 3.6e-13 49.6 6.9 9.8e-05 22.6 0.6 4.6 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJP63929.1 - 9e-07 29.0 0.1 0.0033 17.3 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A MarR_2 PF12802.7 EJP63929.1 - 0.046 13.6 1.0 0.35 10.8 0.4 2.6 2 0 0 2 2 2 0 MarR family Acetyltransf_1 PF00583.25 EJP63930.1 - 1.4e-09 38.2 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP63930.1 - 1.7e-09 37.7 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP63930.1 - 2.8e-07 30.9 0.0 3.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP63930.1 - 9e-07 28.8 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EJP63930.1 - 0.0032 17.6 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJP63930.1 - 0.087 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CPSF73-100_C PF11718.8 EJP63930.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term PanZ PF12568.8 EJP63930.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ RRM_1 PF00076.22 EJP63931.1 - 3.6e-18 65.1 0.0 5.3e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJP63931.1 - 8.3e-05 22.2 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec39 PF08314.11 EJP63932.1 - 1.6e-255 850.2 0.0 1.9e-255 850.0 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 EJP63933.1 - 0.00027 21.1 0.1 0.00032 20.9 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 EJP63933.1 - 0.02 15.3 1.8 0.069 13.5 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) DUF1398 PF07166.11 EJP63934.1 - 0.011 15.8 0.1 0.014 15.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) Myb_DNA-binding PF00249.31 EJP63935.1 - 9.7e-23 80.1 1.8 6.6e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP63935.1 - 2.8e-16 59.5 0.6 6.4e-13 48.7 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EJP63935.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 SLIDE DUF2774 PF11242.8 EJP63935.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Glyco_transf_41 PF13844.6 EJP63936.1 - 3.3e-88 296.2 0.0 3.4e-47 160.9 0.0 3.2 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EJP63936.1 - 8.6e-18 63.3 1.4 0.00097 18.9 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP63936.1 - 6.2e-15 54.0 2.4 0.012 15.7 0.0 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EJP63936.1 - 1.4e-10 41.6 0.9 0.0076 16.9 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP63936.1 - 1.4e-09 38.0 0.7 0.7 10.9 0.0 5.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EJP63936.1 - 2.2e-09 36.9 4.3 0.053 13.4 0.3 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EJP63936.1 - 1.2e-08 34.5 0.7 0.11 12.7 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJP63936.1 - 5.9e-08 32.3 3.3 0.015 14.9 0.0 5.0 3 1 2 5 5 5 3 TPR repeat TPR_12 PF13424.6 EJP63936.1 - 1.5e-07 31.6 4.6 0.0074 16.6 0.3 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJP63936.1 - 9.3e-07 28.8 0.0 0.0031 17.8 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP63936.1 - 4.6e-06 26.3 0.6 0.08 13.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP63936.1 - 0.0056 17.2 1.5 1.3 9.5 0.1 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat BTAD PF03704.17 EJP63936.1 - 0.0077 16.7 0.1 0.15 12.5 0.0 2.7 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 EJP63936.1 - 0.011 15.9 0.9 0.13 12.4 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 EJP63936.1 - 0.034 14.4 0.0 15 5.9 0.0 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat Ribosomal_L11_N PF03946.14 EJP63937.1 - 8.6e-25 86.4 0.2 1.4e-24 85.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EJP63937.1 - 1.5e-15 57.4 0.2 2.7e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 EJP63938.1 - 3.2e-78 262.7 0.0 4.4e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EJP63938.1 - 1.4e-29 102.7 0.1 2.9e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EJP63938.1 - 4.6e-25 87.4 0.1 1.1e-24 86.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EJP63938.1 - 2.4e-15 56.3 6.0 4.3e-15 55.5 6.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EJP63938.1 - 7.1e-14 51.5 0.0 2.4e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EJP63938.1 - 0.08 12.3 1.1 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF728 PF05304.12 EJP63938.1 - 0.18 11.6 0.1 4 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF728) HTH_17 PF12728.7 EJP63938.1 - 0.21 11.8 0.0 0.83 9.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Abhydrolase_1 PF00561.20 EJP63939.1 - 1.9e-12 47.4 0.0 2.1e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP63939.1 - 6.5e-06 26.9 0.0 8.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP63939.1 - 0.00015 21.1 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EJP63939.1 - 0.0019 17.9 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 EJP63939.1 - 0.026 13.5 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ser_hydrolase PF06821.13 EJP63939.1 - 0.036 13.9 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 EJP63939.1 - 0.041 12.8 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 EJP63939.1 - 0.046 13.4 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Ribosomal_S3Ae PF01015.18 EJP63940.1 - 4.6e-88 294.1 2.3 5.6e-88 293.8 2.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Erythro-docking PF09277.11 EJP63940.1 - 0.01 15.7 0.2 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking SUI1 PF01253.22 EJP63940.1 - 0.033 14.7 0.2 0.1 13.2 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 EJP63940.1 - 0.05 13.6 0.4 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO GTP_CH_N PF12471.8 EJP63941.1 - 9.9e-50 169.0 0.0 1.6e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EJP63941.1 - 1.4e-15 57.3 0.0 2.4e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.13 EJP63942.1 - 0.02 14.9 0.2 0.02 14.9 0.2 1.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like UPRTase PF14681.6 EJP63943.1 - 4.9e-79 264.6 0.0 6.5e-79 264.2 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EJP63943.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Ham1p_like PF01725.16 EJP63944.1 - 4.4e-56 189.8 0.0 5e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family tRNA-synt_2b PF00587.25 EJP63945.1 - 1.9e-38 132.2 0.0 3.3e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EJP63945.1 - 2.6e-18 66.2 7.4 4.7e-18 65.4 7.4 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Peptidase_C54 PF03416.19 EJP63945.1 - 0.061 12.7 0.4 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 Peptidase family C54 WAPL PF07814.13 EJP63946.1 - 2.8e-44 151.4 10.7 3e-43 148.0 10.7 2.0 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Methyltr_RsmB-F PF01189.17 EJP63947.1 - 1.2e-75 253.5 0.0 1.8e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EJP63947.1 - 2.9e-08 34.1 0.0 7.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 EJP63947.1 - 0.00043 20.1 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein BHD_2 PF10404.9 EJP63947.1 - 0.034 15.1 0.3 0.24 12.4 0.3 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 FtsJ PF01728.19 EJP63947.1 - 0.074 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 EJP63947.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EJP63947.1 - 0.087 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AAA_18 PF13238.6 EJP63948.1 - 6.7e-28 97.8 0.3 1.2e-27 97.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EJP63948.1 - 1.1e-08 35.6 0.0 1.7e-07 31.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EJP63948.1 - 2.5e-05 24.5 0.1 0.0029 17.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EJP63948.1 - 2.6e-05 24.5 0.1 0.00045 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EJP63948.1 - 2.9e-05 23.8 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase ADK PF00406.22 EJP63948.1 - 4.2e-05 23.7 0.1 0.0021 18.2 0.1 2.3 1 1 0 1 1 1 1 Adenylate kinase AAA PF00004.29 EJP63948.1 - 5e-05 23.7 0.0 0.00048 20.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EJP63948.1 - 0.00013 21.9 0.1 0.00041 20.3 0.0 1.8 2 0 0 2 2 2 1 NTPase dNK PF01712.19 EJP63948.1 - 0.00027 20.9 0.3 0.59 10.0 0.1 2.2 1 1 1 2 2 2 2 Deoxynucleoside kinase KTI12 PF08433.10 EJP63948.1 - 0.001 18.6 0.0 0.0022 17.5 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 SKI PF01202.22 EJP63948.1 - 0.0011 19.2 0.4 0.02 15.0 0.4 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_16 PF13191.6 EJP63948.1 - 0.0012 19.2 0.0 0.0015 19.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP63948.1 - 0.0016 18.7 0.0 0.0034 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 EJP63948.1 - 0.0026 17.9 0.0 0.0048 17.0 0.0 1.7 1 1 0 1 1 1 1 Cytidylate kinase-like family Hydin_ADK PF17213.3 EJP63948.1 - 0.006 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain RNA_helicase PF00910.22 EJP63948.1 - 0.0082 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ATP_bind_1 PF03029.17 EJP63948.1 - 0.013 15.3 0.1 0.03 14.1 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 EJP63948.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EJP63948.1 - 0.031 14.0 2.3 0.075 12.7 0.2 2.5 2 2 1 3 3 3 0 AAA domain SRP54 PF00448.22 EJP63948.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EJP63948.1 - 0.042 14.2 0.1 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EJP63948.1 - 0.05 12.6 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EJP63948.1 - 0.069 12.9 1.6 1.8 8.2 0.4 2.4 1 1 1 2 2 2 0 AAA domain IF2_N PF04760.15 EJP63948.1 - 0.071 12.9 0.1 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region AAA_29 PF13555.6 EJP63948.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_3 PF07726.11 EJP63948.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EJP63948.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EJP63948.1 - 0.14 11.9 0.1 0.29 10.8 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EJP63948.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EJP63948.1 - 0.14 12.1 0.2 1.2 9.1 0.0 2.3 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ArsA_ATPase PF02374.15 EJP63948.1 - 0.35 10.0 3.6 2.1 7.4 0.1 2.7 2 1 1 3 3 3 0 Anion-transporting ATPase Myosin_head PF00063.21 EJP63949.1 - 9.1e-261 866.9 0.5 1.3e-260 866.3 0.5 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EJP63949.1 - 3.2e-26 91.6 2.6 3.2e-26 91.6 2.6 2.7 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 EJP63949.1 - 8.2e-10 37.6 37.6 0.00022 20.8 2.2 6.0 5 0 0 5 5 5 4 IQ calmodulin-binding motif GAS PF13851.6 EJP63949.1 - 0.00033 20.1 13.2 0.00033 20.1 13.2 2.6 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 EJP63949.1 - 0.00077 18.5 20.2 0.0013 17.8 20.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Flagellin_N PF00669.20 EJP63949.1 - 0.001 19.2 4.7 0.001 19.2 4.7 2.2 2 0 0 2 2 1 1 Bacterial flagellin N-terminal helical region AAA_22 PF13401.6 EJP63949.1 - 0.0031 17.8 0.0 0.013 15.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain CALCOCO1 PF07888.11 EJP63949.1 - 0.0046 15.9 21.6 0.0079 15.1 21.6 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Sec34 PF04136.15 EJP63949.1 - 0.0055 16.6 4.6 0.018 14.9 4.6 2.0 1 0 0 1 1 1 1 Sec34-like family AAA_16 PF13191.6 EJP63949.1 - 0.0094 16.3 0.0 0.0094 16.3 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain Myosin_N PF02736.19 EJP63949.1 - 0.015 15.1 0.3 0.015 15.1 0.3 1.8 2 0 0 2 2 1 0 Myosin N-terminal SH3-like domain Baculo_PEP_C PF04513.12 EJP63949.1 - 0.048 13.7 1.7 0.2 11.7 1.7 2.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.6 EJP63949.1 - 0.11 12.2 15.9 0.078 12.7 13.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) zf-C4H2 PF10146.9 EJP63949.1 - 0.19 12.0 6.0 0.7 10.2 6.0 2.0 1 0 0 1 1 1 0 Zinc finger-containing protein KASH_CCD PF14662.6 EJP63949.1 - 0.29 10.9 25.8 0.24 11.2 8.0 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Vps51 PF08700.11 EJP63949.1 - 0.33 11.1 3.4 12 6.1 0.4 3.3 2 0 0 2 2 2 0 Vps51/Vps67 Snapin_Pallidin PF14712.6 EJP63949.1 - 0.48 10.9 15.8 1.1 9.8 5.9 3.3 2 0 0 2 2 2 0 Snapin/Pallidin BRE1 PF08647.11 EJP63949.1 - 0.82 9.8 22.3 0.32 11.1 9.0 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CLZ PF16526.5 EJP63949.1 - 0.99 9.8 10.8 0.18 12.2 0.8 3.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-H PF05837.12 EJP63949.1 - 0.99 9.8 25.4 4.5 7.7 6.5 3.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ABC_tran PF00005.27 EJP63949.1 - 1.5 9.4 4.2 1.6 9.3 0.0 2.9 2 1 0 2 2 1 0 ABC transporter Tropomyosin_1 PF12718.7 EJP63949.1 - 1.8 8.7 25.7 0.95 9.6 6.2 2.7 1 1 1 2 2 2 0 Tropomyosin like DUF4164 PF13747.6 EJP63949.1 - 2.5 8.4 17.8 0.66 10.3 10.9 3.4 2 1 2 4 4 3 0 Domain of unknown function (DUF4164) TMCO5 PF14992.6 EJP63949.1 - 3.1 7.3 15.2 6.8 6.2 15.2 1.5 1 0 0 1 1 1 0 TMCO5 family ING PF12998.7 EJP63949.1 - 3.9 8.1 9.8 3.1 8.4 1.7 3.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Prominin PF05478.11 EJP63949.1 - 4.1 5.3 12.7 1.9 6.3 5.1 2.4 1 1 1 2 2 2 0 Prominin YabA PF06156.13 EJP63949.1 - 5.3 7.7 14.9 18 6.0 6.1 3.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 EJP63949.1 - 7.5 5.8 23.0 2.4 7.4 9.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Enolase_C PF00113.22 EJP63950.1 - 3e-153 509.3 0.0 3.9e-153 508.9 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EJP63950.1 - 1.1e-56 190.6 0.2 1.7e-56 190.0 0.2 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EJP63950.1 - 1.7e-05 24.5 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like KH_8 PF17903.1 EJP63951.1 - 8.8e-07 28.9 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EJP63951.1 - 0.018 14.9 0.4 0.036 13.9 0.4 1.5 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 EJP63952.1 - 2.3e-248 825.1 0.0 2.8e-248 824.9 0.0 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins eIF3_subunit PF08597.10 EJP63953.1 - 1.1e-68 231.8 30.3 1.3e-68 231.5 30.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2201_N PF13203.6 EJP63953.1 - 3.2 7.3 15.0 3 7.4 9.9 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain Pacs-1 PF10254.9 EJP63953.1 - 5 6.0 10.2 0.046 12.7 2.0 1.7 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein DUF4746 PF15928.5 EJP63953.1 - 6.6 6.1 16.2 1.8 7.9 9.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 EJP63953.1 - 6.7 7.0 23.0 3 8.1 1.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.6 EJP63953.1 - 7 6.6 12.8 2.4 8.1 5.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF4407 PF14362.6 EJP63953.1 - 8.1 5.7 19.5 0.76 9.1 11.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AOX PF01786.17 EJP63955.1 - 2.2e-89 298.7 0.1 3.1e-89 298.2 0.1 1.2 1 0 0 1 1 1 1 Alternative oxidase ABC_tran PF00005.27 EJP63955.1 - 2.8e-21 76.5 0.0 5.8e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EJP63955.1 - 9.2e-06 25.2 0.2 0.034 13.6 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP63955.1 - 0.0028 17.5 0.2 1.5 8.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP63955.1 - 0.021 14.6 0.2 0.044 13.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Duffy_binding PF05424.11 EJP63955.1 - 0.054 13.5 0.0 0.31 11.1 0.0 1.8 1 1 1 2 2 2 0 Duffy binding domain AAA_7 PF12775.7 EJP63955.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EJP63955.1 - 0.065 13.3 0.8 0.24 11.5 0.8 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EJP63955.1 - 0.066 13.5 0.7 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EJP63955.1 - 0.12 12.1 0.4 7.9 6.2 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_15 PF13175.6 EJP63955.1 - 0.18 11.5 0.1 1.2 8.8 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 EJP63955.1 - 0.29 10.0 2.0 0.81 8.5 0.1 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain zf-C2H2 PF00096.26 EJP63956.1 - 1.6e-13 50.3 12.4 3.4e-06 27.2 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP63956.1 - 7.2e-13 48.3 8.0 1.8e-07 31.3 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP63956.1 - 6.3e-09 35.9 11.5 0.00038 21.0 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EJP63956.1 - 2.6e-08 33.7 5.4 0.0003 20.7 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP63956.1 - 1.3e-06 28.6 0.3 0.083 13.2 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJP63956.1 - 4.4e-05 23.7 1.7 0.012 15.9 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EJP63956.1 - 0.0061 16.3 5.4 0.39 10.5 0.7 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-Di19 PF05605.12 EJP63956.1 - 0.066 13.5 1.4 0.13 12.6 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 EJP63956.1 - 0.07 13.7 0.8 0.16 12.5 0.8 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 EJP63956.1 - 0.34 11.4 2.3 11 6.6 0.3 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 EJP63956.1 - 0.73 10.1 3.3 16 5.8 0.1 2.4 1 1 1 2 2 2 0 LIM domain FYVE PF01363.21 EJP63956.1 - 1.8 8.8 4.8 3.6 7.8 4.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger C5HCH PF17982.1 EJP63956.1 - 3.6 7.8 6.8 17 5.7 1.1 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain TMF_TATA_bd PF12325.8 EJP63958.1 - 5.3e-39 133.0 9.4 5.3e-39 133.0 9.4 7.1 2 1 4 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EJP63958.1 - 1.1e-15 57.3 12.2 1.1e-15 57.3 12.2 8.4 4 3 2 8 8 8 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EJP63958.1 - 0.0046 17.2 2.4 0.0046 17.2 2.4 6.2 2 1 4 6 6 6 2 Autophagy protein 16 (ATG16) Ank_5 PF13857.6 EJP63959.1 - 3.7e-38 129.1 2.2 6.2e-09 36.0 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP63959.1 - 2.1e-30 105.1 0.0 1.6e-12 47.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP63959.1 - 4.1e-30 103.8 0.9 1.6e-06 28.5 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP63959.1 - 2.5e-26 88.8 0.2 0.00021 21.4 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 EJP63959.1 - 7.1e-24 83.1 0.9 6.7e-06 26.3 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat WD40 PF00400.32 EJP63960.1 - 6.7e-44 147.0 15.9 1.1e-08 35.5 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP63960.1 - 0.00022 21.4 0.5 25 5.3 0.1 4.9 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP63960.1 - 0.012 14.3 2.6 10 4.6 0.0 4.1 1 1 3 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EJP63960.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain AAA PF00004.29 EJP63961.1 - 5.5e-17 62.4 0.0 1.4e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJP63961.1 - 1.8e-11 44.7 0.0 1.3e-10 41.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 EJP63961.1 - 8.2e-11 41.9 0.1 2e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 EJP63961.1 - 5.2e-09 36.5 0.0 2.1e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain BAH PF01426.18 EJP63961.1 - 3.8e-08 33.2 0.0 1.1e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 BAH domain ATPase_2 PF01637.18 EJP63961.1 - 0.0014 18.6 0.0 0.028 14.3 0.0 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EJP63961.1 - 0.0018 18.6 0.0 0.0051 17.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 EJP63961.1 - 0.0039 17.1 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 EJP63961.1 - 0.01 16.4 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EJP63961.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 EJP63961.1 - 0.027 14.3 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EJP63961.1 - 0.052 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.17 EJP63963.1 - 5.8e-26 90.8 1.8 7.5e-26 90.4 1.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EJP63963.1 - 0.01 15.8 6.9 0.067 13.1 2.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit Imm3 PF14425.6 EJP63963.1 - 0.023 14.7 0.5 0.023 14.7 0.5 1.6 2 0 0 2 2 2 0 Immunity protein Imm3 DUF1451 PF07295.11 EJP63963.1 - 0.027 14.5 2.0 1.2 9.1 0.3 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain Prot_ATP_ID_OB PF16450.5 EJP63963.1 - 0.027 14.4 0.3 0.072 13.1 0.1 1.8 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain XhlA PF10779.9 EJP63963.1 - 0.036 14.3 0.5 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 Haemolysin XhlA TACC_C PF05010.14 EJP63963.1 - 0.041 13.7 9.6 1.4 8.7 4.6 2.1 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mnd1 PF03962.15 EJP63963.1 - 0.056 13.7 0.8 0.11 12.8 0.6 1.6 1 1 0 1 1 1 0 Mnd1 HTH domain HR1 PF02185.16 EJP63963.1 - 0.067 13.3 0.7 0.067 13.3 0.7 2.7 3 0 0 3 3 3 0 Hr1 repeat WXG100 PF06013.12 EJP63963.1 - 0.078 13.2 1.5 8.5 6.7 0.1 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 EJP63963.1 - 0.13 12.4 6.8 1.9 8.7 6.4 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec2p PF06428.11 EJP63963.1 - 0.21 11.6 9.1 6.5 6.8 0.1 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Tropomyosin_1 PF12718.7 EJP63963.1 - 0.81 9.8 12.3 0.6 10.3 5.2 2.1 2 0 0 2 2 2 0 Tropomyosin like YvrJ PF12841.7 EJP63963.1 - 1.1 8.9 3.7 0.68 9.5 0.4 2.3 3 0 0 3 3 3 0 YvrJ protein family Spc24 PF08286.11 EJP63963.1 - 6.2 7.1 8.1 14 6.0 2.8 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 tRNA-synt_2b PF00587.25 EJP63964.1 - 2.4e-31 109.1 0.0 5.5e-31 107.9 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EJP63964.1 - 9.3e-08 32.1 0.0 4.9e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain CBF PF03914.17 EJP63965.1 - 2.2e-50 171.0 0.1 2.2e-50 171.0 0.1 3.1 3 1 0 3 3 3 1 CBF/Mak21 family CNOT1_TTP_bind PF16417.5 EJP63965.1 - 0.075 12.2 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain BUD22 PF09073.10 EJP63965.1 - 5.3 6.3 44.8 2.1 7.6 23.9 2.2 2 0 0 2 2 2 0 BUD22 Methyltransf_25 PF13649.6 EJP63966.1 - 4.5e-29 101.0 0.1 7.4e-13 49.0 0.0 3.1 4 0 0 4 4 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EJP63966.1 - 2.1e-27 95.6 0.0 1.3e-14 54.6 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EJP63966.1 - 2.9e-21 76.0 0.0 3.3e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EJP63966.1 - 1.5e-14 54.0 0.0 2.1e-06 27.6 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EJP63966.1 - 8.3e-14 52.1 0.0 1.9e-06 28.5 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EJP63966.1 - 1.7e-11 43.9 0.0 6.4e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MetW PF07021.12 EJP63966.1 - 1.9e-10 40.7 0.0 2.7e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW CMAS PF02353.20 EJP63966.1 - 2.9e-07 30.1 0.0 1.3e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 EJP63966.1 - 1.9e-06 27.2 0.0 0.0052 15.9 0.0 2.3 2 0 0 2 2 2 2 DREV methyltransferase TehB PF03848.14 EJP63966.1 - 4.1e-06 26.4 0.0 3.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Tellurite resistance protein TehB MTS PF05175.14 EJP63966.1 - 2.8e-05 23.7 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase small domain NodS PF05401.11 EJP63966.1 - 0.0001 22.0 0.0 0.0046 16.6 0.0 2.3 2 0 0 2 2 2 1 Nodulation protein S (NodS) GidB PF02527.15 EJP63966.1 - 0.00018 20.9 0.1 0.012 15.0 0.0 2.4 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G FtsJ PF01728.19 EJP63966.1 - 0.00071 19.7 0.0 0.0068 16.5 0.0 2.4 2 1 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 EJP63966.1 - 0.00074 19.3 0.1 1.7 8.3 0.0 3.3 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EJP63966.1 - 0.0015 18.5 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EJP63966.1 - 0.0028 17.7 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EJP63966.1 - 0.026 13.9 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.17 EJP63966.1 - 0.028 13.6 0.3 1.2 8.3 0.0 3.1 4 0 0 4 4 4 0 NNMT/PNMT/TEMT family RrnaAD PF00398.20 EJP63966.1 - 0.075 12.1 0.0 10 5.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 EJP63966.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.6 1 1 0 1 1 1 0 Met-10+ like-protein Methyltransf_9 PF08003.11 EJP63966.1 - 0.13 11.2 0.0 0.43 9.4 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) 4HBT PF03061.22 EJP63967.1 - 6.5e-12 45.6 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily APS_kinase PF01583.20 EJP63968.1 - 4.8e-72 241.0 0.0 6.5e-72 240.6 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EJP63968.1 - 2e-06 28.0 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP63968.1 - 7.3e-05 23.3 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EJP63968.1 - 0.0011 18.5 0.0 0.0012 18.3 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 EJP63968.1 - 0.0065 16.9 0.2 0.011 16.1 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 EJP63968.1 - 0.076 12.9 0.3 0.52 10.1 0.3 2.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF463 PF04317.12 EJP63968.1 - 0.087 11.7 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_29 PF13555.6 EJP63968.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain T_hemolysin PF12261.8 EJP63968.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Thermostable hemolysin PRK PF00485.18 EJP63968.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 EJP63968.1 - 0.18 11.0 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit V-ATPase_C PF03223.15 EJP63969.1 - 3.2e-123 411.8 0.1 3.6e-123 411.6 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APG6_N PF17675.1 EJP63969.1 - 0.15 12.6 1.2 4.8 7.7 0.1 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region mRNA_cap_C PF03919.15 EJP63969.1 - 0.18 12.5 2.0 0.67 10.6 0.1 2.5 2 1 0 3 3 3 0 mRNA capping enzyme, C-terminal domain F-box-like PF12937.7 EJP63971.1 - 8.2e-07 28.8 1.5 1.6e-06 27.9 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EJP63971.1 - 9.2e-06 25.4 0.1 2.3e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup84_Nup100 PF04121.13 EJP63973.1 - 5.9e-167 557.0 2.7 6.8e-167 556.8 2.7 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Rad60-SLD PF11976.8 EJP63974.1 - 7.2e-20 70.6 0.1 8.6e-20 70.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EJP63974.1 - 1.3e-10 40.9 0.1 1.5e-10 40.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family LIM PF00412.22 EJP63975.1 - 2.6e-26 91.6 28.2 5.8e-11 42.5 2.9 3.5 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.9 EJP63975.1 - 0.0075 15.9 0.7 0.0075 15.9 0.7 2.6 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2321) Cactin_mid PF10312.9 EJP63975.1 - 0.057 13.1 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin CHCH PF06747.13 EJP63976.1 - 0.00018 21.5 2.3 0.0003 20.8 2.3 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 EJP63976.1 - 0.012 15.9 3.2 0.051 13.9 3.2 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 EJP63976.1 - 0.016 15.6 4.5 0.13 12.6 0.5 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 EJP63976.1 - 0.29 11.4 2.4 5.3 7.4 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Dynamin_M PF01031.20 EJP63977.1 - 1.5e-109 365.6 0.0 3.5e-109 364.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EJP63977.1 - 1.9e-57 194.0 0.7 3e-57 193.3 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EJP63977.1 - 4.5e-31 106.9 2.2 1.1e-30 105.6 2.2 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EJP63977.1 - 7.4e-05 22.8 0.5 0.00054 20.0 0.5 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Fungal_trans PF04082.18 EJP63978.1 - 2.6e-13 49.6 1.1 3.6e-13 49.1 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain HSBP1 PF06825.12 EJP63978.1 - 0.026 14.4 0.1 0.071 13.0 0.1 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 MGC-24 PF05283.11 EJP63978.1 - 2.6 8.5 7.0 6.3 7.2 2.2 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glutaredoxin PF00462.24 EJP63979.1 - 4.1e-17 62.1 0.0 1.3e-16 60.6 0.0 1.8 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EJP63979.1 - 5.1e-12 45.7 0.0 1.2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EJP63979.1 - 0.028 14.8 0.0 10 6.5 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like HyaE PF07449.11 EJP63979.1 - 0.032 14.2 0.0 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 EJP63979.1 - 0.074 13.5 0.0 1.7 9.1 0.0 2.9 2 2 0 2 2 2 0 Thioredoxin-like domain SH3_9 PF14604.6 EJP63980.1 - 8.4e-28 96.0 6.0 2.9e-14 52.7 0.6 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EJP63980.1 - 6.6e-24 83.3 5.6 1.3e-12 47.1 0.4 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EJP63980.1 - 8.1e-15 54.3 0.1 9.3e-08 31.6 0.1 2.8 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 EJP63980.1 - 1.1e-13 51.1 0.0 3.3e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein CYSTM PF12734.7 EJP63981.1 - 3.9e-12 46.3 15.6 3.9e-12 46.3 15.6 3.3 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 EJP63981.1 - 0.28 11.8 3.4 0.31 11.7 3.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 EJP63982.1 - 2.6e-200 666.8 0.0 3.2e-200 666.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.21 EJP63983.1 - 6.2e-05 23.0 8.0 0.00012 22.1 8.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EJP63983.1 - 0.029 14.4 3.1 0.029 14.4 3.1 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.25 EJP63985.1 - 2.6e-60 204.0 0.0 1.6e-37 129.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP63985.1 - 4.9e-28 98.1 0.0 1.2e-20 73.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EJP63985.1 - 6.5e-15 55.3 0.0 1.3e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EJP63985.1 - 8.8e-07 28.5 0.0 0.00059 19.2 0.0 2.6 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EJP63985.1 - 0.00057 19.9 4.6 0.019 14.9 0.2 4.0 3 2 2 5 5 5 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EJP63985.1 - 0.0094 14.9 0.1 0.018 14.0 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EJP63985.1 - 0.023 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EJP63985.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_N PF08240.12 EJP63986.1 - 7.6e-24 83.7 3.8 1.4e-23 82.8 3.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP63986.1 - 8.3e-16 58.2 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Big_8 PF17961.1 EJP63986.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig domain ThiF PF00899.21 EJP63986.1 - 5.5 6.3 5.5 12 5.1 2.4 2.3 1 1 1 2 2 2 0 ThiF family adh_short_C2 PF13561.6 EJP63987.1 - 2.4e-57 194.2 0.1 3e-57 193.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP63987.1 - 2.1e-45 154.6 0.1 2.8e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP63987.1 - 2.1e-09 37.5 0.1 2.9e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 KR domain ABC_membrane PF00664.23 EJP63988.1 - 2e-79 267.1 38.0 1.1e-45 156.4 9.9 3.8 4 0 0 4 4 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP63988.1 - 2.2e-64 216.1 0.0 1.3e-31 110.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SPX PF03105.19 EJP63988.1 - 3.5e-37 129.2 18.8 3.5e-29 102.9 0.0 3.5 3 0 0 3 3 2 2 SPX domain Na_sulph_symp PF00939.19 EJP63988.1 - 2.1e-30 106.2 39.0 2.1e-30 106.2 39.0 1.7 2 0 0 2 2 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EJP63988.1 - 1.9e-26 93.0 36.3 1.9e-26 93.0 36.3 4.5 4 2 0 4 4 3 1 Citrate transporter SMC_N PF02463.19 EJP63988.1 - 1.3e-12 47.7 3.2 0.00018 21.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP63988.1 - 6.3e-06 25.8 0.2 0.074 12.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP63988.1 - 1.5e-05 25.5 3.7 0.13 12.7 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EJP63988.1 - 2e-05 24.0 0.0 0.28 10.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.20 EJP63988.1 - 0.00017 21.5 0.3 0.013 15.4 0.1 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_22 PF13401.6 EJP63988.1 - 0.00041 20.6 0.6 1.9 8.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 EJP63988.1 - 0.00048 20.1 0.0 0.45 10.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 EJP63988.1 - 0.0012 17.7 0.1 0.031 13.1 0.0 2.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 EJP63988.1 - 0.0015 18.7 0.0 0.81 9.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EJP63988.1 - 0.0015 18.4 4.5 2.4 7.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EJP63988.1 - 0.0022 17.8 5.4 0.065 12.9 0.2 3.3 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 EJP63988.1 - 0.0024 18.3 0.1 0.5 10.8 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EJP63988.1 - 0.0029 17.2 0.2 6.3 6.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF3987 PF13148.6 EJP63988.1 - 0.013 14.5 0.1 2.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_18 PF13238.6 EJP63988.1 - 0.023 15.3 0.1 7.5 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EJP63988.1 - 0.028 14.6 0.4 21 5.5 0.2 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF3318 PF11780.8 EJP63988.1 - 0.14 12.1 0.2 0.41 10.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) AAA_5 PF07728.14 EJP63988.1 - 0.16 12.0 0.1 20 5.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EJP63988.1 - 0.17 12.4 0.8 6 7.3 0.2 2.5 2 0 0 2 2 2 0 AAA domain Synaptobrevin PF00957.21 EJP63988.1 - 0.23 11.3 4.1 1.5 8.7 0.0 4.2 4 0 0 4 4 3 0 Synaptobrevin Pyr_redox_2 PF07992.14 EJP63989.1 - 1.4e-22 80.3 1.0 2.7e-21 76.1 1.3 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP63989.1 - 1.8e-13 50.8 2.0 4.1e-12 46.5 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP63989.1 - 0.00064 19.1 0.8 0.0022 17.3 0.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP63989.1 - 0.0015 17.8 0.2 0.0024 17.1 0.2 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 EJP63989.1 - 0.013 14.8 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EJP63989.1 - 0.019 14.1 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EJP63989.1 - 0.085 12.1 3.8 0.065 12.5 0.7 2.1 2 1 0 2 2 2 0 FAD binding domain Acetyltransf_8 PF13523.6 EJP63990.1 - 1.6e-47 160.9 2.5 2.2e-47 160.4 2.5 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EJP63990.1 - 0.027 15.1 0.4 0.051 14.3 0.4 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 EJP63991.1 - 1.4e-97 327.0 0.0 1.9e-97 326.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP63991.1 - 1.2e-10 42.2 0.0 2.7e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EJP63992.1 - 1.3e-74 251.3 0.0 5.3e-73 246.0 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 EJP63992.1 - 4.5e-64 216.8 0.0 1.3e-39 136.1 0.0 2.7 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EJP63992.1 - 3.8e-25 88.0 0.0 4.3e-14 52.6 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site DUF2722 PF10846.8 EJP63992.1 - 0.02 13.9 2.9 0.038 12.9 2.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) WES_acyltransf PF03007.16 EJP63992.1 - 0.031 14.0 0.0 0.031 14.0 0.0 2.9 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain GH3 PF03321.13 EJP63992.1 - 0.41 9.4 1.5 0.72 8.6 0.0 2.0 3 0 0 3 3 3 0 GH3 auxin-responsive promoter Spt20 PF12090.8 EJP63992.1 - 3.4 7.2 13.4 6.3 6.3 13.4 1.3 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 EJP63992.1 - 8 6.6 16.3 25 5.0 16.3 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4050 PF13259.6 EJP63993.1 - 4.5e-55 186.8 0.3 4.5e-55 186.8 0.3 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF4050) PAPA-1 PF04795.12 EJP63995.1 - 1e-26 93.5 6.7 1e-26 93.5 6.7 3.5 3 0 0 3 3 3 1 PAPA-1-like conserved region SDA1 PF05285.12 EJP63995.1 - 3.4 7.0 65.0 0.021 14.3 41.5 2.3 1 1 1 2 2 2 0 SDA1 Pex14_N PF04695.13 EJP63996.1 - 9.7e-34 117.3 1.5 9.7e-34 117.3 1.5 2.8 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Syntaphilin PF15290.6 EJP63996.1 - 1.7 8.2 4.1 0.9 9.1 0.5 2.1 2 1 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Chromo PF00385.24 EJP63997.1 - 1.6e-07 31.1 0.6 4.5e-07 29.7 0.6 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Glyco_transf_15 PF01793.16 EJP63998.1 - 4.7e-126 420.4 4.5 5.8e-126 420.1 4.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 EJP63999.1 - 1.5e-29 101.9 0.5 2e-29 101.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 EJP63999.1 - 0.17 12.6 0.0 0.46 11.3 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein S12 Acyl-CoA_dh_1 PF00441.24 EJP64000.1 - 1.1e-40 139.3 4.1 2.3e-40 138.2 4.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EJP64000.1 - 4e-30 104.8 1.7 9.6e-30 103.5 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EJP64000.1 - 2.6e-24 85.2 0.0 1.2e-23 83.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EJP64000.1 - 7.7e-18 65.1 1.5 1.8e-17 63.9 1.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EJP64000.1 - 0.0001 22.0 0.1 0.00038 20.2 0.1 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Pkinase PF00069.25 EJP64001.1 - 5.9e-60 202.9 0.1 1.4e-59 201.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64001.1 - 1.9e-35 122.4 0.0 3.6e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EJP64001.1 - 2.2e-24 85.3 21.4 1.9e-12 47.1 4.6 3.2 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 EJP64001.1 - 6.9e-19 67.5 30.7 8.8e-12 44.7 10.6 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EJP64001.1 - 1.1e-08 35.6 2.1 4.4e-08 33.7 2.1 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EJP64001.1 - 0.00014 22.1 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Caskin-Pro-rich PF16907.5 EJP64001.1 - 0.0019 18.7 0.1 0.0019 18.7 0.1 3.0 3 0 0 3 3 2 1 Proline rich region of Caskin proteins Kinase-like PF14531.6 EJP64001.1 - 0.0046 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EJP64001.1 - 0.026 14.2 0.1 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAT1 PF09770.9 EJP64001.1 - 1.7 6.8 11.2 2.8 6.1 11.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-RING_9 PF13901.6 EJP64001.1 - 2 8.3 23.4 2 8.4 8.2 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon She9_MDM33 PF05546.11 EJP64002.1 - 5.1e-80 268.0 3.7 6.6e-80 267.6 3.7 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family ATG16 PF08614.11 EJP64002.1 - 0.22 11.7 11.3 0.44 10.8 2.5 2.6 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EJP64002.1 - 2 8.4 5.5 6.4 6.8 0.1 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 EJP64002.1 - 2.5 8.5 6.0 0.61 10.5 1.5 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HAD PF12710.7 EJP64003.1 - 5.2e-21 75.9 0.0 7.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EJP64003.1 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EJP64003.1 - 0.013 15.8 0.1 0.14 12.4 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EJP64003.1 - 0.026 13.9 0.0 6 6.2 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase MFS_1 PF07690.16 EJP64005.1 - 4.8e-19 68.5 66.9 8.5e-17 61.1 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 EJP64005.1 - 0.2 11.4 0.0 0.2 11.4 0.0 3.8 4 0 0 4 4 4 0 Bacteriophage holin family, superfamily II-like F-box PF00646.33 EJP64006.1 - 0.0066 16.3 1.3 0.018 14.9 0.0 2.4 3 0 0 3 3 3 1 F-box domain DUF2431 PF10354.9 EJP64007.1 - 1.3e-58 198.0 0.0 1.6e-41 142.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) Methyltr_RsmB-F PF01189.17 EJP64007.1 - 0.0066 16.1 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF3246 PF11596.8 EJP64007.1 - 0.44 10.0 15.7 0.087 12.2 8.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Eapp_C PF10238.9 EJP64007.1 - 3.1 7.9 15.0 3 7.9 0.5 3.1 3 0 0 3 3 3 0 E2F-associated phosphoprotein FYDLN_acid PF09538.10 EJP64007.1 - 5.7 7.7 33.2 4.1 8.1 12.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) TLP-20 PF06088.11 EJP64007.1 - 6 6.7 14.0 3.7 7.4 3.3 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Peptidase_S49_N PF08496.10 EJP64007.1 - 6.4 6.8 7.5 5 7.2 0.2 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SRI PF08236.11 EJP64008.1 - 9.9e-23 80.1 7.6 2.6e-22 78.8 7.6 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EJP64008.1 - 1.6e-16 61.2 0.2 1.6e-16 61.2 0.2 3.8 3 2 0 3 3 3 1 SET domain AWS PF17907.1 EJP64008.1 - 4.2e-11 42.7 7.0 4.2e-11 42.7 7.0 2.5 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 EJP64008.1 - 1.2e-05 25.2 2.3 1.5e-05 24.9 0.3 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.26 EJP64008.1 - 0.00013 22.0 0.4 0.00028 20.9 0.4 1.6 1 0 0 1 1 1 1 WW domain DUF4587 PF15248.6 EJP64008.1 - 6.3 7.7 8.2 0.55 11.1 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) Aminotran_3 PF00202.21 EJP64010.1 - 1.5e-117 392.7 0.0 1.7e-117 392.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EJP64010.1 - 0.012 14.8 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Voltage_CLC PF00654.20 EJP64011.1 - 5.8e-90 302.1 25.6 7e-90 301.8 21.7 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel Sas10 PF09368.10 EJP64012.1 - 4.4e-29 100.8 7.9 4.4e-29 100.8 7.9 3.3 4 1 1 5 5 5 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EJP64012.1 - 1.1e-10 41.9 0.1 4.8e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Tubulin PF00091.25 EJP64013.1 - 2e-69 233.8 0.0 1.1e-68 231.3 0.0 1.9 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EJP64013.1 - 9.5e-41 138.9 0.1 1.6e-40 138.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EJP64013.1 - 2.5e-05 24.5 0.0 5.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EJP64013.1 - 0.0065 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 EJP64013.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Vps51 PF08700.11 EJP64015.1 - 4.5e-13 49.1 0.0 2.2e-12 46.9 0.0 2.3 1 0 0 1 1 1 1 Vps51/Vps67 Peptidase_S46 PF10459.9 EJP64015.1 - 0.0032 16.2 11.6 0.035 12.8 1.3 2.3 2 0 0 2 2 2 2 Peptidase S46 Rep_fac_C PF08542.11 EJP64015.1 - 0.0032 17.8 0.6 1.6 9.2 0.0 3.8 4 0 0 4 4 4 1 Replication factor C C-terminal domain ImcF-related_N PF14331.6 EJP64015.1 - 0.032 13.6 0.3 7.3 5.9 0.1 2.6 2 0 0 2 2 2 0 ImcF-related N-terminal domain PsbW PF07123.12 EJP64015.1 - 0.034 14.1 1.0 2.9 7.9 0.4 2.4 1 1 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) PEP-utilisers_N PF05524.13 EJP64015.1 - 5.9 7.1 8.8 5.8 7.1 0.6 4.0 3 2 1 4 4 4 0 PEP-utilising enzyme, N-terminal ECH_1 PF00378.20 EJP64016.1 - 3.5e-21 75.7 0.0 4.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP64016.1 - 5.7e-16 58.9 0.0 6.6e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1731 PF08338.11 EJP64016.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) RNA_pol_I_A49 PF06870.12 EJP64017.1 - 6.9e-104 347.8 4.1 8.3e-104 347.5 4.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.25 EJP64018.1 - 3.8e-52 177.2 0.0 6.6e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64018.1 - 2.8e-31 108.7 0.0 4.8e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EJP64018.1 - 3.1e-11 43.5 0.1 1.1e-10 41.7 0.1 2.0 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 EJP64018.1 - 5.5e-06 25.9 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EJP64018.1 - 2.8e-05 23.1 0.1 7.5e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EJP64018.1 - 0.1 12.9 0.0 0.62 10.4 0.0 2.3 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 EJP64018.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zeta_toxin PF06414.12 EJP64019.1 - 5.2e-45 153.2 0.1 1.4e-44 151.7 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 EJP64019.1 - 4.8e-08 33.3 0.0 1.8e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP64019.1 - 0.005 17.2 0.7 0.074 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain CCB2_CCB4 PF11152.8 EJP64019.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 Phage_tail_APC PF16778.5 EJP64019.1 - 0.073 13.0 1.1 0.12 12.2 1.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Sigma54_activat PF00158.26 EJP64019.1 - 0.08 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 EJP64019.1 - 0.097 12.9 0.2 0.96 9.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 EJP64019.1 - 0.2 11.6 0.0 4.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EJP64019.1 - 0.23 11.0 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3543 PF12063.8 EJP64020.1 - 1.5e-93 312.8 1.8 2.4e-93 312.1 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EJP64020.1 - 5e-61 206.4 0.0 9.7e-61 205.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64020.1 - 5.1e-42 143.9 0.0 9.8e-42 143.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EJP64020.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aminotran_3 PF00202.21 EJP64021.1 - 4e-123 411.1 0.0 4.5e-123 410.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EJP64021.1 - 0.004 16.5 0.1 0.011 15.0 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EJP64021.1 - 0.062 12.5 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_transf_22 PF03901.17 EJP64022.1 - 2.6e-78 264.1 15.0 3.1e-78 263.9 15.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.6 EJP64022.1 - 0.17 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Fer2_3 PF13085.6 EJP64023.1 - 1.7e-32 111.7 0.0 2.8e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EJP64023.1 - 2.7e-08 34.2 6.9 2.7e-08 34.2 6.9 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EJP64023.1 - 4.1e-08 33.2 3.5 4.1e-08 33.2 3.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EJP64023.1 - 1.1e-07 32.2 13.5 2.6e-07 31.0 9.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EJP64023.1 - 0.0035 17.9 6.1 0.0035 17.9 6.1 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 EJP64023.1 - 0.0043 17.0 0.5 0.0043 17.0 0.5 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EJP64023.1 - 0.0057 16.8 0.6 0.46 10.7 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EJP64023.1 - 0.16 12.2 12.7 1.3 9.2 11.0 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain RhoGAP PF00620.27 EJP64024.1 - 5.8e-38 130.1 0.0 9.8e-38 129.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Med30 PF11315.8 EJP64025.1 - 0.019 15.2 8.4 1.1 9.4 4.4 2.6 2 0 0 2 2 2 0 Mediator complex subunit 30 Zn_clus PF00172.18 EJP64025.1 - 0.029 14.5 13.1 0.057 13.6 13.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EJP64025.1 - 0.067 13.2 14.0 0.011 15.8 10.3 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 EJP64025.1 - 0.2 10.4 3.9 0.31 9.8 3.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FlxA PF14282.6 EJP64025.1 - 1.5 8.9 24.6 3.1 7.8 24.6 1.5 1 0 0 1 1 1 0 FlxA-like protein Spt20 PF12090.8 EJP64025.1 - 2.9 7.5 14.5 5.2 6.6 14.5 1.3 1 0 0 1 1 1 0 Spt20 family MFS_1 PF07690.16 EJP64026.1 - 7.6e-41 140.2 53.2 4.7e-40 137.6 51.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP64026.1 - 1.2e-11 43.8 23.7 2.7e-11 42.6 23.5 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2196 PF09962.9 EJP64027.1 - 4.4e-23 81.0 2.7 6.6e-23 80.5 2.7 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Clathrin PF00637.20 EJP64028.1 - 4.2e-199 652.4 36.0 1.6e-32 112.4 1.4 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EJP64028.1 - 2.9e-33 112.5 0.3 6.7e-07 29.3 0.1 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EJP64028.1 - 5.2e-32 109.6 2.1 7.7e-32 109.0 0.5 2.3 2 0 0 2 2 2 1 Clathrin-H-link TPR_14 PF13428.6 EJP64028.1 - 0.0001 22.8 7.4 95 4.2 0.1 8.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 EJP64028.1 - 0.022 14.8 7.7 14 6.0 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJP64028.1 - 0.024 14.8 5.6 1.9 8.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EJP64028.1 - 0.035 14.4 5.1 52 4.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat 6PF2K PF01591.18 EJP64028.1 - 0.044 13.1 0.2 0.18 11.1 0.2 2.0 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TPR_1 PF00515.28 EJP64028.1 - 0.048 13.5 6.9 11 6.0 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EJP64028.1 - 0.057 13.9 5.0 14 6.3 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EJP64028.1 - 1.5 9.1 13.4 16 5.9 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF1720 PF08226.11 EJP64028.1 - 5.6 7.5 7.8 3.1 8.3 3.9 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF1720) DPPIV_N PF00930.21 EJP64029.1 - 2.3e-105 352.2 0.4 3.1e-105 351.8 0.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EJP64029.1 - 3.8e-55 186.7 1.7 1.5e-54 184.7 2.3 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EJP64029.1 - 6.2e-06 27.0 5.6 0.00079 20.1 5.6 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP64029.1 - 0.00034 20.3 0.2 0.00092 18.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EJP64029.1 - 0.001 18.7 1.0 0.011 15.3 0.5 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 EJP64029.1 - 0.26 11.3 1.3 6 6.9 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Alg6_Alg8 PF03155.15 EJP64030.1 - 4.6e-128 428.2 27.8 4e-82 276.7 8.7 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Stevor PF17410.2 EJP64031.1 - 0.016 14.7 0.7 0.021 14.4 0.0 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Ribosomal_L12_N PF16320.5 EJP64031.1 - 0.091 12.5 5.4 0.18 11.5 5.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 EJP64032.1 - 2.1e-27 95.5 11.3 2.4e-27 95.3 11.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RibD_C PF01872.17 EJP64032.1 - 0.045 13.6 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 RibD C-terminal domain SPT2 PF08243.11 EJP64033.1 - 3.8e-11 43.5 24.6 9.7e-09 35.7 24.6 2.4 1 1 0 1 1 1 1 SPT2 chromatin protein Cwf_Cwc_15 PF04889.12 EJP64033.1 - 0.0032 17.2 6.8 0.0071 16.1 6.8 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NUFIP1 PF10453.9 EJP64034.1 - 0.00027 20.7 1.3 0.00043 20.1 0.0 2.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 EJP64034.1 - 0.036 14.1 6.8 0.067 13.3 6.8 1.5 1 0 0 1 1 1 0 Zinc finger domain DUF1003 PF06210.11 EJP64034.1 - 0.085 13.0 1.3 0.2 11.8 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) zf-CCCH PF00642.24 EJP64034.1 - 0.09 12.7 5.8 0.19 11.7 5.8 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF5320 PF17253.2 EJP64034.1 - 2.7 9.1 13.6 0.9 10.6 0.5 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5320) PIEZO PF15917.5 EJP64034.1 - 5.6 6.4 6.8 0.24 10.8 0.9 1.7 2 0 0 2 2 2 0 Piezo PHC2_SAM_assoc PF16616.5 EJP64034.1 - 9.9 7.0 15.6 0.19 12.5 5.0 3.0 3 0 0 3 3 3 0 Unstructured region on Polyhomeotic-like protein 1 and 2 RNA_pol_Rbc25 PF08292.12 EJP64035.1 - 2.3e-33 115.2 2.7 4.2e-32 111.1 2.7 2.1 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EJP64035.1 - 7.4e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EJP64035.1 - 0.037 14.4 0.0 0.064 13.6 0.0 1.5 1 1 0 1 1 1 0 S1 RNA binding domain EMC3_TMCO1 PF01956.16 EJP64036.1 - 4.5e-53 179.5 0.2 7e-53 178.8 0.2 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 EJP64037.1 - 3.2e-53 179.8 0.6 3.8e-53 179.6 0.6 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MMS19_N PF14500.6 EJP64038.1 - 2e-50 171.8 0.1 7e-50 170.0 0.1 1.9 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EJP64038.1 - 1.9e-17 63.5 4.5 3.4e-16 59.4 2.3 3.1 2 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Ipi1_N PF12333.8 EJP64038.1 - 0.007 16.9 0.4 1.2 9.7 0.0 4.0 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation Alpha-E PF04168.12 EJP64038.1 - 0.056 13.2 0.1 0.57 9.9 0.0 2.5 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. ATP11 PF06644.11 EJP64039.1 - 2e-103 345.9 0.1 2.4e-103 345.7 0.1 1.0 1 0 0 1 1 1 1 ATP11 protein DUF1472 PF07339.12 EJP64039.1 - 0.019 15.5 0.6 0.045 14.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1472) Abhydro_lipase PF04083.16 EJP64040.1 - 2e-18 65.7 0.0 4.3e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EJP64040.1 - 4.5e-07 29.8 0.1 1.4e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP64040.1 - 9.2e-06 25.1 0.0 2.1e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EJP64040.1 - 0.17 10.7 0.0 0.34 9.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme AAA PF00004.29 EJP64041.1 - 6.3e-51 172.2 0.0 4.6e-43 146.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJP64041.1 - 3.7e-05 24.2 0.5 0.015 15.6 0.0 3.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EJP64041.1 - 0.00014 21.7 0.0 0.00056 19.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EJP64041.1 - 0.0003 20.5 5.1 0.088 12.6 0.1 3.1 3 0 0 3 3 3 2 AAA+ lid domain Parvo_NS1 PF01057.17 EJP64041.1 - 0.0012 18.0 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 EJP64041.1 - 0.0034 17.5 0.0 0.0087 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EJP64041.1 - 0.0069 16.7 0.0 0.035 14.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EJP64041.1 - 0.0073 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EJP64041.1 - 0.0083 16.5 0.0 0.039 14.4 0.0 2.2 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.6 EJP64041.1 - 0.0086 15.7 0.3 0.044 13.4 0.0 2.3 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 EJP64041.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EJP64041.1 - 0.023 14.1 0.1 0.058 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EJP64041.1 - 0.025 14.6 0.1 0.13 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EJP64041.1 - 0.037 13.4 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EJP64041.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EJP64041.1 - 0.072 13.1 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EJP64041.1 - 0.085 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EJP64041.1 - 0.088 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EJP64041.1 - 0.11 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 EJP64041.1 - 0.11 12.7 0.0 0.4 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EJP64041.1 - 0.14 12.6 0.0 0.56 10.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 EJP64041.1 - 0.17 11.9 0.0 7 6.7 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 EJP64041.1 - 0.2 11.7 0.0 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain SH3BGR PF04908.15 EJP64042.1 - 2.4e-05 24.4 5.8 0.00018 21.6 0.0 3.2 3 0 0 3 3 3 2 SH3-binding, glutamic acid-rich protein Nuc_recep-AF1 PF11825.8 EJP64043.1 - 0.47 10.5 11.9 0.84 9.7 11.9 1.6 1 1 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 DUF5349 PF17298.2 EJP64043.1 - 7.6 6.2 9.9 8.9 6.0 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) MaoC_dehydratas PF01575.19 EJP64044.1 - 0.00051 19.6 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Phosphodiest PF01663.22 EJP64045.1 - 1.2e-13 51.4 0.1 2.6e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EJP64045.1 - 6.9e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EJP64045.1 - 0.00026 20.4 0.2 0.00049 19.5 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily HET PF06985.11 EJP64046.1 - 2.3e-32 112.4 0.5 3.8e-32 111.7 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cytochrom_B561 PF03188.16 EJP64047.1 - 0.00087 19.4 7.2 0.002 18.2 7.2 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 K_channel_TID PF07941.11 EJP64047.1 - 0.017 15.5 8.1 0.017 15.5 8.1 4.5 4 2 1 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain Phage_holin_2_4 PF16082.5 EJP64047.1 - 0.44 10.3 0.0 0.44 10.3 0.0 3.7 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like DUF3382 PF11862.8 EJP64047.1 - 0.96 9.8 8.2 8.5 6.7 3.5 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF3382) DUF4131 PF13567.6 EJP64047.1 - 1.3 8.7 7.9 3.5 7.2 1.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.24 EJP64048.1 - 1.8e-62 211.7 20.4 2.2e-62 211.4 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP64048.1 - 9.3e-09 34.7 23.6 9.3e-09 34.7 23.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Flavi_NS4A PF01350.17 EJP64048.1 - 8.1 6.4 6.8 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Fungal_trans PF04082.18 EJP64049.1 - 1e-12 47.7 0.0 2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64049.1 - 1.5e-06 28.2 2.6 2.7e-06 27.4 2.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2Fe-2S_Ferredox PF11591.8 EJP64049.1 - 0.38 10.6 3.1 0.6 10.0 0.2 2.4 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide Pkinase PF00069.25 EJP64050.1 - 1.6e-37 129.3 0.0 2.3e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64050.1 - 1.5e-26 93.3 0.0 2.1e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP64050.1 - 0.0013 17.6 0.0 0.003 16.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EJP64050.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cwf_Cwc_15 PF04889.12 EJP64050.1 - 0.013 15.3 4.6 0.027 14.2 4.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein APH PF01636.23 EJP64050.1 - 0.023 14.6 0.0 3.4 7.5 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 EJP64051.1 - 6.2e-11 42.7 0.3 0.61 11.0 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Nup160 PF11715.8 EJP64051.1 - 0.052 12.2 0.0 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF1921 PF09081.10 EJP64051.1 - 0.23 11.7 1.8 76 3.7 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1921) Hpt PF01627.23 EJP64052.1 - 7.2e-12 45.4 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Hpt domain AKAP7_NLS PF10469.9 EJP64053.1 - 1.3e-30 106.9 0.0 1.6e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 EJP64053.1 - 0.0035 17.5 0.3 0.045 13.9 0.1 2.5 2 1 1 3 3 3 1 LigT like Phosphoesterase DUF812 PF05667.11 EJP64054.1 - 0.029 13.3 14.9 0.042 12.7 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Csm1_N PF18504.1 EJP64054.1 - 0.061 13.7 9.5 0.48 10.8 0.1 3.5 2 2 1 3 3 3 0 Csm1 N-terminal domain CCDC106 PF15794.5 EJP64054.1 - 1.1 8.9 17.7 0.49 10.1 9.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF641 PF04859.12 EJP64054.1 - 2.3 8.5 10.0 2.4 8.5 0.4 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) zf-RING_11 PF17123.5 EJP64056.1 - 2.5e-13 49.5 5.2 4.8e-13 48.6 5.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger FHA PF00498.26 EJP64056.1 - 2.7e-13 50.1 0.0 5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 EJP64056.1 - 8.4e-07 29.2 9.1 1.8e-06 28.2 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EJP64056.1 - 0.0028 17.9 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 EJP64056.1 - 0.0069 16.3 6.1 0.018 15.0 6.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EJP64056.1 - 0.0081 16.0 9.1 0.015 15.1 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EJP64056.1 - 0.03 14.2 4.5 0.076 12.9 4.5 1.8 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 EJP64056.1 - 0.061 13.6 4.6 0.23 11.8 4.6 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EJP64056.1 - 0.089 12.7 8.9 0.18 11.7 8.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP64056.1 - 0.18 11.8 8.3 0.44 10.6 8.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger OrfB_Zn_ribbon PF07282.11 EJP64056.1 - 1.1 9.2 3.1 22 5.1 3.1 2.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Peptidase_M16_C PF05193.21 EJP64057.1 - 1.9e-53 181.2 0.0 3.7e-53 180.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EJP64057.1 - 1.3e-41 142.0 0.0 6.9e-39 133.2 0.0 2.3 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Pex14_N PF04695.13 EJP64057.1 - 0.0087 16.7 2.2 0.016 15.9 2.2 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.11 EJP64057.1 - 0.028 12.5 2.3 0.033 12.3 2.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 EJP64057.1 - 1.2 7.9 6.2 2.1 7.1 6.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain S1 PF00575.23 EJP64059.1 - 4.4e-84 276.9 39.8 5.8e-16 58.6 0.7 13.2 14 0 0 14 14 14 11 S1 RNA binding domain RNase_II_C_S1 PF18614.1 EJP64059.1 - 6.4e-09 35.6 3.1 1.1 9.2 0.0 6.7 6 0 0 6 6 6 3 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 EJP64059.1 - 1.6e-06 28.4 2.6 0.014 16.2 0.0 5.3 4 1 2 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP64059.1 - 0.00027 21.4 0.5 0.21 12.1 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP64059.1 - 0.00073 20.1 0.9 0.017 15.8 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat SDA1 PF05285.12 EJP64059.1 - 0.0013 18.2 22.4 0.0013 18.2 22.4 3.2 2 1 0 3 3 2 1 SDA1 S1_2 PF13509.6 EJP64059.1 - 0.009 16.1 0.2 15 5.7 0.0 4.9 5 0 0 5 5 5 0 S1 domain TFIIA PF03153.13 EJP64059.1 - 0.034 14.2 38.0 0.32 11.0 22.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_2 PF07719.17 EJP64059.1 - 0.036 14.2 0.6 0.13 12.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 EJP64059.1 - 0.061 13.6 0.1 0.21 11.9 0.1 2.0 1 0 0 1 1 1 0 PPR repeat Suf PF05843.14 EJP64059.1 - 0.064 13.2 9.0 0.29 11.1 0.0 3.8 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EJP64059.1 - 0.13 12.5 0.1 0.42 11.0 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat BUD22 PF09073.10 EJP64059.1 - 3.3 7.0 46.6 1.1 8.5 29.1 2.6 2 0 0 2 2 2 0 BUD22 Fungal_trans PF04082.18 EJP64061.1 - 6.7e-17 61.4 0.1 9.5e-17 60.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64061.1 - 4e-16 58.8 25.4 1.7e-08 34.4 9.9 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP-1 PF03085.15 EJP64061.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2462 PF09495.10 EJP64062.1 - 4e-12 46.7 9.9 7.5e-12 45.8 9.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Pyridoxal_deC PF00282.19 EJP64063.1 - 5.3e-23 81.3 0.0 4.1e-21 75.1 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EJP64063.1 - 0.087 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EJP64063.1 - 0.14 11.3 0.0 0.34 10.0 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3995 PF13160.6 EJP64063.1 - 0.17 12.3 2.7 0.22 11.9 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) Zn_clus PF00172.18 EJP64064.1 - 2.2e-11 43.6 7.4 3.7e-11 42.9 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP64065.1 - 4.8e-12 45.4 0.0 1.5e-11 43.8 0.0 1.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Serglycin PF04360.12 EJP64065.1 - 1.3 8.9 5.1 0.28 11.1 0.9 1.9 2 0 0 2 2 2 0 Serglycin Fungal_trans_2 PF11951.8 EJP64066.1 - 3.1e-08 32.8 0.3 5.1e-08 32.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64066.1 - 8.5e-08 32.2 9.7 1.9e-07 31.1 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.28 EJP64067.1 - 2e-22 79.1 0.2 2.2e-22 79.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 EJP64067.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 V-ATPase subunit H Peptidase_M48 PF01435.18 EJP64068.1 - 6.2e-40 137.1 0.0 8.7e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Methyltransf_23 PF13489.6 EJP64069.1 - 1.3e-15 57.6 0.0 2.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP64069.1 - 3.4e-07 30.9 0.0 9.9e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP64069.1 - 3.7e-06 26.8 0.0 6.4e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP64069.1 - 0.00065 20.4 0.0 0.0048 17.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP64069.1 - 0.027 13.8 0.0 0.19 11.0 0.0 2.3 3 1 0 3 3 3 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 EJP64069.1 - 0.035 13.9 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.14 EJP64069.1 - 0.1 12.1 0.0 0.27 10.8 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EJP64069.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Kinesin PF00225.23 EJP64070.1 - 1.6e-111 372.5 0.0 1.6e-111 372.5 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 EJP64070.1 - 4.6e-47 160.5 0.0 1.4e-46 158.9 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 EJP64070.1 - 1.5e-34 119.7 18.1 1.7e-30 106.5 0.3 3.8 2 1 0 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 EJP64070.1 - 1.5e-24 86.7 0.7 3.3e-24 85.5 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 EJP64070.1 - 9e-07 29.2 0.3 3.6e-06 27.3 0.3 2.1 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 EJP64070.1 - 0.00089 19.6 0.0 0.0059 16.9 0.1 2.4 2 0 0 2 2 2 1 FHA domain PH PF00169.29 EJP64070.1 - 0.0046 17.4 0.0 3.4 8.2 0.0 2.9 3 0 0 3 3 3 1 PH domain Zw10 PF06248.13 EJP64070.1 - 0.9 8.0 9.4 0.11 11.0 4.2 1.9 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Exonuc_VII_L PF02601.15 EJP64070.1 - 1.5 8.3 10.7 4.9 6.6 8.8 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Ten1 PF12658.7 EJP64071.1 - 6.3e-25 87.5 0.0 7.2e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit DUF2585 PF10755.9 EJP64071.1 - 0.0062 16.3 0.0 0.008 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2585) Ten1_2 PF15490.6 EJP64071.1 - 0.0083 15.8 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF952 PF06108.12 EJP64072.1 - 3.5e-22 78.2 0.0 4.9e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Sulphotransf PF09037.10 EJP64072.1 - 0.078 12.5 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Stf0 sulphotransferase Peptidase_M1 PF01433.20 EJP64073.1 - 1.2e-42 145.9 0.3 1.7e-42 145.5 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EJP64073.1 - 6.5e-35 119.6 0.0 1.1e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EJP64073.1 - 2.9e-22 79.8 0.0 4.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 EJP64073.1 - 0.027 14.1 0.4 0.16 11.6 0.0 2.3 3 0 0 3 3 3 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 EJP64073.1 - 0.55 10.6 2.2 8.2 6.9 2.2 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Uds1 PF15456.6 EJP64074.1 - 1.1e-34 119.4 6.5 1.1e-34 119.4 6.5 2.2 2 0 0 2 2 2 1 Up-regulated During Septation Mucin PF01456.17 EJP64074.1 - 0.0025 17.8 10.2 0.0025 17.8 10.2 3.9 3 2 0 3 3 3 1 Mucin-like glycoprotein Stathmin PF00836.19 EJP64074.1 - 0.038 14.0 0.5 0.12 12.3 0.5 1.8 1 0 0 1 1 1 0 Stathmin family TMF_TATA_bd PF12325.8 EJP64074.1 - 0.23 11.7 2.5 0.61 10.3 2.5 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EJP64074.1 - 0.39 9.5 2.7 0.66 8.8 2.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 EJP64074.1 - 7.7 7.1 6.8 8.9 6.9 3.9 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region PXA PF02194.15 EJP64075.1 - 1.5e-34 119.6 0.1 2.8e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EJP64075.1 - 7.1e-22 78.1 0.1 3.2e-21 76.0 0.1 2.3 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EJP64075.1 - 1.3e-06 28.3 0.0 3.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 PX domain PC4 PF02229.16 EJP64076.1 - 2.1e-22 78.5 0.6 6.1e-22 77.0 0.1 1.9 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) 2OG-FeII_Oxy PF03171.20 EJP64077.1 - 3.3e-18 66.0 0.0 6.2e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EJP64077.1 - 1.5e-14 54.8 0.0 2.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HMG-CoA_red PF00368.18 EJP64078.1 - 7.4e-143 476.0 2.7 9.9e-143 475.6 2.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EJP64078.1 - 2.5e-46 157.4 0.8 3.9e-46 156.7 0.8 1.3 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EJP64078.1 - 6.7e-15 55.3 4.9 4.6e-14 52.5 4.9 2.2 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EJP64078.1 - 3.4e-07 28.8 2.2 5.5e-07 28.1 2.2 1.2 1 0 0 1 1 1 1 Patched family Isochorismatase PF00857.20 EJP64079.1 - 5.9e-28 98.2 0.1 1.2e-27 97.3 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family ComA PF02679.15 EJP64079.1 - 0.031 13.8 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Peripla_BP_6 PF13458.6 EJP64079.1 - 0.031 13.9 0.1 0.05 13.3 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Ntox46 PF15538.6 EJP64081.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 46 Zn_clus PF00172.18 EJP64081.1 - 2.7 8.2 6.3 0.47 10.6 1.8 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EJP64082.1 - 1.2e-07 31.4 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EJP64082.1 - 6e-06 25.8 0.0 1.2e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP64082.1 - 0.0014 18.6 0.3 0.041 13.8 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EJP64082.1 - 0.0064 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 AP_endonuc_2 PF01261.24 EJP64083.1 - 1.1e-35 123.1 0.0 1.5e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_transf_64 PF09258.10 EJP64084.1 - 1.1e-51 175.5 0.0 1.2e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 EJP64084.1 - 2e-05 24.6 0.1 2.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EJP64084.1 - 0.0011 18.7 1.4 0.004 17.0 1.5 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 KGG PF10685.9 EJP64086.1 - 2.8e-27 94.1 15.7 9.6e-12 44.8 0.8 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Amino_oxidase PF01593.24 EJP64087.1 - 3.6e-11 43.0 0.0 8.4e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP64087.1 - 3.6e-09 36.7 0.0 8.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP64087.1 - 0.00015 21.1 0.2 0.021 14.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP64087.1 - 0.00059 19.2 0.0 0.00099 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP64087.1 - 0.0024 17.1 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EJP64087.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EJP64087.1 - 0.022 13.9 0.1 0.86 8.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EJP64087.1 - 0.034 12.9 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 EJP64087.1 - 0.038 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EJP64087.1 - 0.083 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EJP64087.1 - 0.21 11.6 0.2 0.91 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding IBR PF01485.21 EJP64088.1 - 4.3e-05 23.6 6.3 4.3e-05 23.6 6.3 2.7 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-CCCH PF00642.24 EJP64088.1 - 0.00012 21.9 2.4 0.00043 20.1 2.4 2.1 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EJP64088.1 - 0.012 15.7 1.5 0.012 15.7 1.5 2.4 2 1 0 2 2 2 0 Zinc finger domain C1_2 PF03107.16 EJP64088.1 - 0.81 10.0 12.6 0.38 11.1 1.1 2.7 2 0 0 2 2 2 0 C1 domain Prok-RING_4 PF14447.6 EJP64088.1 - 1 9.3 17.0 0.075 12.9 5.3 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 EJP64088.1 - 1.7 9.2 5.0 1.6 9.3 0.9 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Mito_carr PF00153.27 EJP64089.1 - 2.9e-39 132.9 4.5 3.1e-17 62.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.24 EJP64090.1 - 7.7e-112 374.4 10.7 9.2e-112 374.2 10.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP64090.1 - 3.8e-34 118.2 24.1 6e-33 114.2 13.1 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EJP64090.1 - 6.5e-05 21.7 15.6 0.0034 16.0 1.1 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 EJP64090.1 - 0.0021 16.6 0.2 0.0035 15.8 0.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 EJP64090.1 - 0.021 13.8 0.5 0.021 13.8 0.5 1.9 3 0 0 3 3 3 0 Sugar-tranasporters, 12 TM Phage_holin_3_2 PF04550.12 EJP64090.1 - 0.065 13.8 1.6 0.33 11.5 0.3 2.6 2 0 0 2 2 2 0 Phage holin family 2 Trp_oprn_chp PF09534.10 EJP64090.1 - 0.066 13.0 0.2 0.066 13.0 0.2 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) UQ_con PF00179.26 EJP64091.1 - 3.5e-37 127.2 0.0 4.5e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP64091.1 - 3.7e-07 29.9 0.0 9e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic E2 family B UBA_3 PF09288.10 EJP64091.1 - 5.8e-05 22.8 0.1 0.0001 22.0 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.22 EJP64091.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain CoA_binding PF02629.19 EJP64092.1 - 6.1e-27 94.2 1.8 1.5e-26 92.9 0.2 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EJP64092.1 - 4e-23 81.9 0.5 6e-23 81.4 0.5 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EJP64092.1 - 2e-08 34.1 0.1 3.3e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EJP64092.1 - 0.005 17.3 0.0 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Zn_clus PF00172.18 EJP64094.1 - 2.7e-10 40.2 8.3 4.8e-10 39.4 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Radical_SAM_C PF16199.5 EJP64095.1 - 6.9e-32 109.3 0.0 1.5e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EJP64095.1 - 1.8e-16 60.9 0.1 6.9e-16 59.1 0.0 1.9 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EJP64095.1 - 6.2e-11 42.6 0.1 1.9e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP64095.1 - 1e-05 25.5 0.0 3e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP64095.1 - 0.029 14.8 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MBD PF01429.19 EJP64096.1 - 0.038 13.7 0.1 0.77 9.5 0.1 2.1 2 0 0 2 2 2 0 Methyl-CpG binding domain ZipA_C PF04354.13 EJP64096.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain JMY PF15871.5 EJP64096.1 - 0.15 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Methyltransf_25 PF13649.6 EJP64097.1 - 7.5e-13 49.0 0.0 1.9e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP64097.1 - 1.2e-07 32.2 0.0 3.9e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP64097.1 - 1.6e-06 28.0 0.0 4.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP64097.1 - 2.5e-05 24.9 0.0 0.00015 22.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP64097.1 - 0.00015 21.6 0.0 0.00078 19.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EJP64097.1 - 0.022 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 EJP64097.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_24 PF13578.6 EJP64097.1 - 0.036 15.1 0.0 0.14 13.2 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EJP64097.1 - 0.12 11.8 0.0 0.65 9.4 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF3328 PF11807.8 EJP64098.1 - 3.1e-48 164.4 0.9 4.2e-48 164.0 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 EJP64100.1 - 8.7e-21 74.2 24.8 8.7e-21 74.2 24.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HupE_UreJ_2 PF13795.6 EJP64100.1 - 0.011 15.5 0.2 0.032 13.9 0.2 1.9 1 0 0 1 1 1 0 HupE / UreJ protein Methyltransf_31 PF13847.6 EJP64101.1 - 6.1e-10 39.1 0.0 1.3e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EJP64101.1 - 1.2e-06 29.5 0.2 9e-05 23.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP64101.1 - 1.3e-06 29.0 0.1 3.8e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EJP64101.1 - 2.1e-05 23.8 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 EJP64101.1 - 3.6e-05 23.6 0.0 9.7e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EJP64101.1 - 7.6e-05 22.6 0.0 0.00016 21.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP64101.1 - 0.00044 20.9 0.0 0.0011 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP64101.1 - 0.0052 16.1 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EJP64101.1 - 0.024 14.1 0.1 1.3 8.4 0.0 2.6 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_32 PF13679.6 EJP64101.1 - 0.025 14.6 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EJP64101.1 - 0.031 15.0 0.2 0.067 13.9 0.2 1.7 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EJP64101.1 - 0.067 12.8 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW TA_inhibitor PF17574.2 EJP64101.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) GCD14 PF08704.10 EJP64101.1 - 0.11 12.1 0.1 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 EJP64101.1 - 0.12 12.0 0.3 0.73 9.4 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase small domain UBA_3 PF09288.10 EJP64101.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Fibrillarin PF01269.17 EJP64101.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin TehB PF03848.14 EJP64101.1 - 0.2 11.1 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB ABC_tran PF00005.27 EJP64102.1 - 4.3e-43 147.1 1.0 1.8e-20 73.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP64102.1 - 8e-20 71.6 31.1 2.8e-14 53.4 10.9 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP64102.1 - 2.8e-11 43.3 4.8 0.0048 16.4 0.7 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 EJP64102.1 - 4e-06 27.0 0.0 0.074 13.1 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 EJP64102.1 - 1.2e-05 24.9 0.2 0.077 12.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJP64102.1 - 1.3e-05 25.3 0.2 0.13 12.4 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 EJP64102.1 - 3.7e-05 23.9 1.6 0.065 13.3 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain NB-ARC PF00931.22 EJP64102.1 - 0.00037 19.7 4.6 0.0021 17.3 0.7 2.9 2 1 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.7 EJP64102.1 - 0.00053 19.0 0.1 0.023 13.6 0.1 2.3 2 0 0 2 2 2 1 AAA-like domain T2SSE PF00437.20 EJP64102.1 - 0.00057 19.0 0.8 0.051 12.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 EJP64102.1 - 0.0026 17.7 1.2 2.3 8.1 0.1 2.7 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 EJP64102.1 - 0.0026 17.7 1.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase NTPase_1 PF03266.15 EJP64102.1 - 0.0032 17.4 2.1 0.084 12.8 0.0 3.4 4 0 0 4 4 4 1 NTPase AAA_21 PF13304.6 EJP64102.1 - 0.0051 16.7 4.3 28 4.4 0.2 4.4 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EJP64102.1 - 0.0063 16.8 6.3 0.85 9.9 0.1 3.4 3 1 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 EJP64102.1 - 0.0067 16.4 0.3 13 5.6 0.0 3.7 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 EJP64102.1 - 0.0077 15.6 1.0 0.52 9.6 0.0 2.5 3 0 0 3 3 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 EJP64102.1 - 0.0079 15.1 1.2 0.4 9.5 0.1 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EJP64102.1 - 0.01 16.2 0.6 2.8 8.3 0.0 3.0 2 2 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 EJP64102.1 - 0.01 15.3 0.6 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EJP64102.1 - 0.014 15.9 1.7 1.3 9.4 0.1 3.6 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EJP64102.1 - 0.017 14.9 0.2 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 EJP64102.1 - 0.021 15.0 2.9 0.83 9.9 0.0 3.3 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EJP64102.1 - 0.026 14.3 0.3 2.7 7.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EJP64102.1 - 0.056 12.9 0.5 3.8 6.9 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.19 EJP64102.1 - 0.058 13.0 3.3 12 5.5 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EJP64102.1 - 0.061 12.9 0.1 0.96 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJP64102.1 - 0.11 12.9 0.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EJP64102.1 - 0.13 11.9 0.1 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EJP64102.1 - 0.14 11.5 0.5 16 4.8 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.6 EJP64102.1 - 0.16 12.5 0.1 5.7 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EJP64102.1 - 0.41 10.9 2.6 5 7.4 0.1 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase bZIP_2 PF07716.15 EJP64103.1 - 0.00055 20.0 7.6 0.0013 18.8 7.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EJP64103.1 - 0.0039 17.3 7.8 0.0039 17.3 7.8 1.8 2 0 0 2 2 2 1 bZIP transcription factor CCDC24 PF15669.5 EJP64103.1 - 3.1 7.6 7.3 0.14 12.0 1.6 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Csm1 PF12539.8 EJP64104.1 - 5.5e-28 97.4 0.0 1.5e-27 96.0 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF5094 PF17015.5 EJP64104.1 - 0.032 14.4 0.0 0.032 14.4 0.0 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF5094) Bap31_Bap29_C PF18035.1 EJP64104.1 - 0.12 12.4 6.7 11 6.1 0.0 3.3 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Syntaxin_2 PF14523.6 EJP64104.1 - 0.23 11.8 8.0 0.11 12.9 3.0 3.0 2 1 1 3 3 3 0 Syntaxin-like protein Lectin_N PF03954.14 EJP64104.1 - 0.33 10.7 2.8 1.7 8.4 2.6 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3138 PF11336.8 EJP64104.1 - 0.64 8.6 4.7 0.97 8.0 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CAF1A PF12253.8 EJP64104.1 - 0.85 9.8 4.7 3.1 8.0 4.7 2.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Rootletin PF15035.6 EJP64104.1 - 1.6 8.7 19.0 5.2 7.0 19.0 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion BLOC1_2 PF10046.9 EJP64104.1 - 1.9 8.8 11.4 7.3 7.0 4.3 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Uso1_p115_C PF04871.13 EJP64104.1 - 3 8.2 26.4 2.6 8.4 15.8 3.2 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA PF00004.29 EJP64105.1 - 4e-36 124.4 0.0 6.5e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP64105.1 - 7.2e-11 41.7 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 EJP64105.1 - 1e-05 25.6 0.0 2.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJP64105.1 - 1.8e-05 25.1 0.1 0.0034 17.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EJP64105.1 - 4.5e-05 23.2 0.0 9.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EJP64105.1 - 5.9e-05 23.5 0.1 0.0019 18.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EJP64105.1 - 7.1e-05 22.8 0.1 0.00043 20.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJP64105.1 - 9.9e-05 22.5 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EJP64105.1 - 0.00051 19.8 0.0 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EJP64105.1 - 0.0028 17.8 0.4 0.0052 16.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.6 EJP64105.1 - 0.0032 17.6 0.0 0.0068 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 EJP64105.1 - 0.0032 17.8 0.0 0.0086 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 EJP64105.1 - 0.0032 16.9 0.0 1.2 8.5 0.0 2.9 2 1 1 3 3 3 1 Bacterial TniB protein AAA_18 PF13238.6 EJP64105.1 - 0.0034 17.9 0.1 0.014 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EJP64105.1 - 0.0055 16.1 0.1 0.012 15.0 0.1 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EJP64105.1 - 0.0069 16.6 0.1 0.016 15.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 EJP64105.1 - 0.0096 15.9 0.0 0.021 14.8 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 EJP64105.1 - 0.014 15.0 0.1 0.17 11.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EJP64105.1 - 0.021 14.6 0.0 0.052 13.3 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 EJP64105.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.13 EJP64105.1 - 0.055 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EJP64105.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EJP64105.1 - 0.07 12.4 0.6 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin TOM6p PF15184.6 EJP64105.1 - 0.083 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog NACHT PF05729.12 EJP64105.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EJP64105.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 EJP64105.1 - 0.17 11.1 0.1 0.32 10.2 0.1 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 EJP64105.1 - 0.18 11.8 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MFS_1 PF07690.16 EJP64106.1 - 6.9e-15 54.8 33.1 1.7e-09 37.1 13.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EJP64106.1 - 1.1e-08 34.9 4.8 3e-08 33.5 4.8 1.7 1 0 0 1 1 1 1 Nodulin-like CcmD PF04995.14 EJP64106.1 - 3.6 7.7 5.5 3.8 7.7 0.2 3.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Serinc PF03348.15 EJP64107.1 - 5.8e-162 539.5 6.6 6.5e-162 539.3 6.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) TcpE PF12648.7 EJP64107.1 - 0.23 12.0 0.0 0.23 12.0 0.0 3.4 2 1 0 3 3 3 0 TcpE family PGAP1 PF07819.13 EJP64108.1 - 5.6e-94 314.2 0.0 8.2e-94 313.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EJP64108.1 - 3.5e-06 27.8 0.0 9.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EJP64108.1 - 0.0025 17.7 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EJP64108.1 - 0.0034 16.7 0.0 0.0089 15.3 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EJP64108.1 - 0.0072 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 EJP64108.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 EJP64108.1 - 0.034 13.8 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 EJP64108.1 - 0.22 10.4 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family MutL_C PF08676.11 EJP64109.1 - 2.9e-19 69.3 0.0 7.6e-19 67.9 0.0 1.8 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EJP64109.1 - 4.2e-18 65.1 0.0 1.6e-17 63.3 0.0 2.0 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EJP64109.1 - 1.1e-13 51.2 2.1 2.1e-13 50.3 0.1 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EJP64109.1 - 1.8e-07 31.6 0.0 5.3e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_2 PF07992.14 EJP64111.1 - 3.2e-07 29.9 0.0 9.4e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ETF PF01012.21 EJP64112.1 - 2.8e-38 131.6 7.6 4.6e-38 130.9 7.6 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EJP64112.1 - 8.2e-34 115.5 0.4 2.1e-33 114.2 0.4 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.17 EJP64113.1 - 9.4e-32 109.2 0.1 1.8e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EJP64113.1 - 2.1e-30 104.5 4.7 4.9e-30 103.3 4.7 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EJP64113.1 - 9.8e-10 38.5 0.0 2.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP64113.1 - 3.1e-05 24.1 0.1 6.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EJP64113.1 - 0.0014 18.4 4.6 0.0031 17.3 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF1586 PF07625.11 EJP64113.1 - 0.43 10.7 4.7 0.14 12.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) Carn_acyltransf PF00755.20 EJP64114.1 - 8.6e-203 675.2 0.0 9.7e-203 675.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.19 EJP64115.1 - 6.9e-119 397.0 0.1 6.9e-119 397.0 0.1 1.4 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EJP64115.1 - 9.7e-58 194.2 1.4 1.3e-57 193.8 1.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal F-box-like PF12937.7 EJP64117.1 - 0.00038 20.3 0.3 0.0013 18.6 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP64117.1 - 1.9 8.5 7.0 0.36 10.8 1.7 2.7 3 0 0 3 3 3 0 F-box domain Phe_hydrox_dim PF07976.12 EJP64118.1 - 0.1 12.7 0.1 0.14 12.2 0.1 1.3 1 1 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain p450 PF00067.22 EJP64120.1 - 7.2e-77 259.1 0.0 8.2e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 7tm_3 PF00003.22 EJP64120.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR GMC_oxred_N PF00732.19 EJP64122.1 - 6.5e-71 239.1 0.0 8.9e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP64122.1 - 1.8e-22 80.4 0.0 3.2e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EJP64122.1 - 0.0011 18.6 0.0 0.0029 17.2 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP64122.1 - 0.0011 19.1 0.1 0.0036 17.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EJP64122.1 - 0.0016 17.7 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EJP64122.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EJP64122.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EJP64122.1 - 0.082 12.1 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PfkB PF00294.24 EJP64123.1 - 2.3e-14 53.4 0.0 9.3e-07 28.4 0.1 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.23 EJP64124.1 - 1.6e-98 328.3 0.2 2.4e-98 327.7 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJP64124.1 - 1.2e-30 105.9 0.1 2.3e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EJP64124.1 - 5e-24 84.5 1.0 9.8e-24 83.6 1.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EJP64124.1 - 1.3e-12 48.2 0.0 3.4e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EJP64124.1 - 8.5e-08 31.8 0.0 1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EJP64124.1 - 0.00099 19.0 0.0 0.0033 17.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJP64124.1 - 0.0048 16.6 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EJP64124.1 - 0.0099 15.9 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF3246 PF11596.8 EJP64124.1 - 0.35 10.3 14.6 1.2 8.5 14.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) BUD22 PF09073.10 EJP64124.1 - 4.3 6.6 12.1 6.6 5.9 12.1 1.2 1 0 0 1 1 1 0 BUD22 Exo70 PF03081.15 EJP64125.1 - 2e-87 293.7 0.0 3.2e-87 293.1 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit DUF4355 PF14265.6 EJP64125.1 - 0.029 14.6 0.2 0.49 10.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Apolipoprotein PF01442.18 EJP64125.1 - 0.04 13.8 4.1 0.066 13.1 0.6 2.9 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain PRT_C PF08372.10 EJP64125.1 - 0.17 11.6 0.2 26 4.5 0.1 2.5 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Baculo_PEP_C PF04513.12 EJP64125.1 - 1.2 9.2 7.4 4.7 7.2 0.3 4.1 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 EJP64125.1 - 2.2 9.0 4.7 2.4 8.9 0.0 3.2 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) 2_5_RNA_ligase2 PF13563.6 EJP64126.1 - 1.6e-25 89.8 1.1 3.4e-25 88.7 1.1 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 EJP64126.1 - 1.2e-18 67.6 0.6 3e-18 66.3 0.6 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 EJP64126.1 - 1e-13 50.8 0.0 1.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 EJP64126.1 - 2.1e-08 34.0 0.1 6.7e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EJP64126.1 - 0.015 15.1 0.0 0.065 13.1 0.0 2.1 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase MFS_1 PF07690.16 EJP64127.1 - 1e-41 143.0 63.9 2.5e-41 141.8 61.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily FA_hydroxylase PF04116.13 EJP64128.1 - 5.7e-23 81.7 11.7 5.7e-23 81.7 11.7 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TPT PF03151.16 EJP64129.1 - 2.6e-23 82.8 21.0 3.2e-23 82.5 21.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 EJP64129.1 - 0.11 11.9 16.4 0.18 11.3 14.0 2.3 2 1 0 2 2 2 0 Solute carrier family 35 Sulfatase PF00884.23 EJP64131.1 - 3.8e-19 69.2 1.4 2.7e-18 66.4 2.0 2.1 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 EJP64131.1 - 5.9e-05 22.8 0.1 9.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EJP64131.1 - 0.13 10.9 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) RNA_pol_I_TF PF04090.12 EJP64132.1 - 5.3e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase I specific initiation factor Acetyltransf_3 PF13302.7 EJP64133.1 - 1.3e-08 35.6 0.0 2.1e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP64133.1 - 1.4e-08 34.9 0.0 2.9e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP64133.1 - 5.7e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJP64133.1 - 0.00087 19.5 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EJP64133.1 - 0.0018 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP64133.1 - 0.013 15.4 0.4 0.11 12.5 0.1 2.1 1 1 1 2 2 2 0 FR47-like protein Acetyltransf_10 PF13673.7 EJP64133.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5519 PF17648.1 EJP64134.1 - 0.026 14.4 0.8 0.056 13.3 0.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5519) Cys_Met_Meta_PP PF01053.20 EJP64135.1 - 4.3e-138 460.0 0.0 5e-138 459.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EJP64135.1 - 6.6e-07 29.0 0.1 3.6e-06 26.5 0.0 2.0 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EJP64135.1 - 1e-05 24.7 0.0 3.3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EJP64135.1 - 0.013 14.7 0.0 0.036 13.4 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase POTRA_2 PF08479.11 EJP64135.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type WD40 PF00400.32 EJP64136.1 - 1.4e-11 44.7 21.8 0.00056 20.7 0.7 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Yip1 PF04893.17 EJP64137.1 - 1.2e-12 47.9 20.6 2.1e-12 47.1 20.6 1.6 1 1 0 1 1 1 1 Yip1 domain 7TM_transglut PF14402.6 EJP64137.1 - 0.022 14.2 8.5 0.031 13.7 8.5 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase DUF1282 PF06930.12 EJP64137.1 - 0.3 10.9 12.4 0.98 9.2 12.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Ran_BP1 PF00638.18 EJP64138.1 - 1.3e-12 48.1 0.2 8.6e-06 26.0 0.1 2.4 2 0 0 2 2 2 2 RanBP1 domain Glyco_hydro_75 PF07335.11 EJP64138.1 - 0.031 14.5 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 GREB1 PF15782.5 EJP64138.1 - 6.5 3.7 5.5 2.7 5.0 2.8 1.4 1 1 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DEAD PF00270.29 EJP64139.1 - 5.2e-28 98.0 0.0 8.7e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EJP64139.1 - 8.9e-21 74.4 0.6 2.8e-20 72.8 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EJP64139.1 - 1.6e-11 44.5 0.0 9.6e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP64139.1 - 6e-07 29.6 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 EJP64139.1 - 5e-05 23.7 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like Val_tRNA-synt_C PF10458.9 EJP64139.1 - 0.089 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Mo-co_dimer PF03404.16 EJP64140.1 - 5e-61 204.7 0.1 9.2e-61 203.9 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EJP64140.1 - 3e-55 186.5 0.0 5e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 EJP64140.1 - 1.1e-33 115.6 0.0 2.3e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EJP64140.1 - 1.5e-28 99.6 0.0 7.1e-28 97.4 0.0 2.2 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EJP64140.1 - 7.8e-21 74.0 0.0 1.9e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EJP64140.1 - 0.0046 17.1 0.0 0.77 9.9 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MIF4G PF02854.19 EJP64141.1 - 1.6e-53 181.5 0.0 1.4e-26 93.5 0.0 3.7 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EJP64141.1 - 2e-39 135.4 4.3 2e-39 135.4 4.3 3.1 4 0 0 4 4 4 1 Up-frameshift suppressor 2 RseA_C PF03873.13 EJP64141.1 - 0.15 12.3 0.8 0.39 11.0 0.8 1.7 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Chitin_synth_2 PF03142.15 EJP64142.1 - 8.5e-25 87.4 4.1 1.9e-22 79.6 2.5 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EJP64142.1 - 4.6e-17 62.6 6.1 4.6e-17 62.6 6.1 1.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EJP64142.1 - 2e-10 41.0 0.1 6.6e-10 39.3 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EJP64142.1 - 0.013 15.3 0.1 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.20 EJP64143.1 - 3.4e-163 544.0 0.1 3.4e-163 544.0 0.1 1.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EJP64143.1 - 1.4e-12 47.1 0.4 2.3e-11 43.1 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 EJP64143.1 - 0.001 19.5 1.4 0.65 10.5 0.1 3.5 2 2 0 2 2 2 2 Cell division protein FtsA GTP_EFTU PF00009.27 EJP64144.1 - 6.1e-36 123.8 0.8 2.3e-35 121.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EJP64144.1 - 8.4e-20 70.9 0.0 2.4e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EJP64144.1 - 5.5e-08 33.1 0.1 5.5e-08 33.1 0.1 3.8 5 0 0 5 5 5 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EJP64144.1 - 5.7e-08 32.5 1.3 4.8e-07 29.6 1.3 2.6 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EJP64144.1 - 1.6e-07 31.4 0.1 3.8e-06 27.0 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EJP64144.1 - 0.00055 20.1 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EJP64144.1 - 0.0025 17.6 0.1 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TrkA_C PF02080.21 EJP64144.1 - 0.2 11.5 0.6 2 8.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-C domain MMS1_N PF10433.9 EJP64145.1 - 3e-65 220.7 0.0 9e-64 215.9 0.0 2.1 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term AHSA1 PF08327.11 EJP64145.1 - 0.0023 18.2 0.1 0.0053 17.0 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein RabGAP-TBC PF00566.18 EJP64146.1 - 2.4e-20 73.1 0.0 3.3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF883 PF05957.13 EJP64146.1 - 0.0044 17.6 0.6 0.0044 17.6 0.6 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Vps52 PF04129.12 EJP64147.1 - 1.9e-126 422.8 4.1 2.7e-126 422.3 4.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family DUF4795 PF16043.5 EJP64147.1 - 0.0023 17.6 2.0 0.0054 16.4 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Sec3_C PF09763.9 EJP64147.1 - 0.0038 15.7 6.6 0.026 12.9 6.2 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec3 Filament PF00038.21 EJP64147.1 - 0.0078 15.8 0.1 0.035 13.7 0.1 2.0 2 0 0 2 2 2 1 Intermediate filament protein DUF3450 PF11932.8 EJP64147.1 - 0.03 13.6 1.3 1.1 8.5 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Apolipoprotein PF01442.18 EJP64147.1 - 0.037 13.9 1.3 0.19 11.6 1.2 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain COG2 PF06148.11 EJP64147.1 - 0.088 12.9 1.0 0.24 11.5 0.2 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mer2 PF09074.10 EJP64147.1 - 0.19 11.5 5.0 0.66 9.8 0.0 3.1 1 1 2 3 3 3 0 Mer2 Baculo_PEP_C PF04513.12 EJP64147.1 - 0.48 10.5 2.3 4.3 7.4 0.2 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ubiquitin PF00240.23 EJP64148.1 - 5.4e-32 109.4 0.5 1.1e-31 108.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EJP64148.1 - 6.9e-30 102.7 10.4 1.3e-29 101.9 10.4 1.4 1 0 0 1 1 1 1 Ribosomal L40e family eIF-5a PF01287.20 EJP64148.1 - 4e-27 94.1 1.3 8.4e-27 93.1 1.3 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Rad60-SLD PF11976.8 EJP64148.1 - 2.2e-13 49.8 0.4 4.8e-13 48.7 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EJP64148.1 - 0.001 19.5 0.1 0.0026 18.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain zf-RRN7 PF11781.8 EJP64148.1 - 0.0012 18.5 1.7 0.0031 17.1 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 NTR2 PF15458.6 EJP64148.1 - 0.012 15.2 0.5 0.021 14.4 0.5 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 EFP_N PF08207.12 EJP64148.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain TBK1_ULD PF18396.1 EJP64148.1 - 0.036 14.0 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EJP64148.1 - 0.055 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Yip1 PF04893.17 EJP64149.1 - 9.4e-11 41.7 17.3 9.4e-11 41.7 17.3 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 EJP64149.1 - 0.12 11.8 3.6 0.38 10.2 2.8 2.0 2 1 0 2 2 2 0 YIF1 Rhodanese PF00581.20 EJP64150.1 - 2.3e-14 53.8 0.0 3.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.22 EJP64151.1 - 6.2e-49 167.0 0.0 8.6e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I9 PF05922.16 EJP64152.1 - 6.8e-10 39.5 0.0 3.1e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 BCDHK_Adom3 PF10436.9 EJP64153.1 - 7.8e-45 152.6 0.0 1e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EJP64153.1 - 2.5e-12 47.3 0.0 8.1e-11 42.4 0.0 2.7 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EJP64153.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Chitin_synth_2 PF03142.15 EJP64154.1 - 4.9e-228 758.0 0.2 6.7e-228 757.6 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 EJP64154.1 - 4.3e-15 55.4 0.8 2.4e-13 49.8 2.6 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EJP64154.1 - 1.3e-13 51.3 1.8 1.3e-13 51.3 1.8 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EJP64154.1 - 2.4e-13 50.5 0.0 1.9e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 EJP64154.1 - 2.6e-09 37.1 1.2 7.3e-06 26.0 0.0 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Myosin_head PF00063.21 EJP64154.1 - 2.3e-07 29.5 0.0 6.9e-07 27.9 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 EJP64154.1 - 0.00037 20.3 0.0 0.085 12.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EJP64154.1 - 0.00045 19.7 0.0 0.0016 17.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 EJP64155.1 - 1.3e-250 832.5 2.6 1.9e-250 832.0 2.6 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EJP64155.1 - 9.8e-71 238.9 0.0 9.2e-70 235.7 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EJP64155.1 - 5.1e-16 58.3 0.3 2e-15 56.4 0.4 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EJP64155.1 - 1.4e-14 54.0 0.1 1.3e-09 38.0 0.0 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EJP64155.1 - 1.8e-12 47.6 3.7 1.8e-12 47.6 3.7 2.3 3 0 0 3 3 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EJP64155.1 - 1.7e-11 44.5 0.0 5.4e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EJP64155.1 - 2.7e-06 27.3 0.0 0.0031 17.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 RsgA_GTPase PF03193.16 EJP64155.1 - 0.028 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EJP64155.1 - 0.038 13.7 0.2 0.13 12.0 0.0 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP64155.1 - 0.039 14.3 0.2 0.16 12.4 0.1 2.1 2 0 0 2 2 1 0 AAA ATPase domain ABC_tran PF00005.27 EJP64155.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Glyco_transf_21 PF13506.6 EJP64155.1 - 0.051 13.0 0.1 0.35 10.3 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 21 AAA_7 PF12775.7 EJP64155.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EJP64155.1 - 0.072 13.2 0.1 5.7 7.1 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Wzy_C PF04932.15 EJP64155.1 - 0.1 12.2 0.3 5.3 6.7 0.0 2.6 2 0 0 2 2 2 0 O-Antigen ligase AAA_25 PF13481.6 EJP64155.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EJP64155.1 - 0.16 12.4 0.0 0.46 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Npa1 PF11707.8 EJP64156.1 - 8.9e-98 327.8 0.1 2.4e-97 326.3 0.0 1.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EJP64156.1 - 3.9e-61 206.2 0.1 3e-60 203.3 0.0 2.5 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Arm PF00514.23 EJP64156.1 - 0.062 13.4 0.0 0.59 10.3 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DNA_ligase_A_N PF04675.14 EJP64156.1 - 0.1 12.9 0.6 4.7 7.5 0.0 2.7 2 0 0 2 2 2 0 DNA ligase N terminus Nuc_rec_co-act PF08815.10 EJP64156.1 - 0.19 11.6 1.2 18 5.3 0.1 2.9 3 0 0 3 3 3 0 Nuclear receptor coactivator MFS_1 PF07690.16 EJP64157.1 - 3.1e-22 79.0 19.2 5.4e-15 55.2 13.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.19 EJP64158.1 - 1.8e-30 105.9 0.0 5.9e-17 61.3 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP64158.1 - 4e-11 42.7 0.1 1.2e-09 37.9 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP64158.1 - 1.3e-09 37.7 0.0 1.1e-08 34.7 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP64158.1 - 4.1e-07 29.4 0.7 1.6e-05 24.3 0.0 2.8 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EJP64158.1 - 9.5e-05 22.4 0.0 0.084 12.9 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EJP64158.1 - 0.0068 16.6 0.0 0.024 14.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP64158.1 - 0.058 13.0 2.1 3.9 6.9 0.0 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase His_Phos_2 PF00328.22 EJP64160.1 - 6.5e-60 203.5 0.0 7.6e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FeoB_associated PF12669.7 EJP64161.1 - 0.28 11.6 2.4 0.5 10.8 2.4 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Kinocilin PF15033.6 EJP64161.1 - 0.3 10.7 0.5 0.49 10.0 0.5 1.3 1 0 0 1 1 1 0 Kinocilin protein Inositol_P PF00459.25 EJP64162.1 - 2.6e-63 214.1 0.0 3.1e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TRAM_2 PF18693.1 EJP64162.1 - 0.08 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 TRAM domain Gamma-thionin PF00304.20 EJP64162.1 - 0.13 12.6 0.4 0.23 11.7 0.4 1.3 1 0 0 1 1 1 0 Gamma-thionin family MFS_1 PF07690.16 EJP64163.1 - 4.3e-44 150.9 25.7 6.4e-44 150.3 25.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP64163.1 - 4.7e-09 35.6 11.0 4.7e-09 35.6 11.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP64163.1 - 2.2e-05 23.1 2.4 3.2e-05 22.6 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MRI PF15325.6 EJP64163.1 - 0.063 14.4 4.7 0.12 13.4 4.7 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection MAGE_N PF12440.8 EJP64163.1 - 0.072 13.8 5.8 0.14 12.8 5.8 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal IMUP PF15761.5 EJP64163.1 - 2 9.1 10.1 3.5 8.3 10.1 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein La PF05383.17 EJP64164.1 - 1.9e-17 63.1 0.0 3.2e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EJP64164.1 - 2.2e-07 30.6 0.1 4.2e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sterol_MT_C PF08498.10 EJP64165.1 - 5.6e-27 93.8 0.1 9.5e-27 93.1 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EJP64165.1 - 1.1e-24 86.9 0.0 2.3e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP64165.1 - 8.6e-22 77.7 0.0 2.1e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP64165.1 - 1.4e-19 70.6 0.0 2.3e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP64165.1 - 1.4e-19 70.4 0.0 2.1e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP64165.1 - 1.3e-12 47.5 0.0 2.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EJP64165.1 - 1.7e-12 47.9 0.0 6.4e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EJP64165.1 - 1.9e-11 43.8 0.0 2.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 EJP64165.1 - 0.00021 20.9 0.1 0.00056 19.5 0.1 1.6 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 EJP64165.1 - 0.0014 18.6 0.1 0.0034 17.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EJP64165.1 - 0.0034 17.2 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EJP64165.1 - 0.0034 16.9 0.0 0.0085 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EJP64165.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 EJP64165.1 - 0.014 15.3 0.0 0.095 12.5 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase N2227 PF07942.12 EJP64165.1 - 0.018 14.2 0.1 1.7 7.8 0.0 2.3 1 1 1 2 2 2 0 N2227-like protein MetW PF07021.12 EJP64165.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.13 EJP64165.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 UPF0020 PF01170.18 EJP64165.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_29 PF03141.16 EJP64165.1 - 0.18 10.4 0.1 0.48 8.9 0.1 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 EJP64165.1 - 0.25 10.4 0.0 0.41 9.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GLTP PF08718.11 EJP64166.1 - 1.5e-45 155.2 0.0 2e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Abhydrolase_3 PF07859.13 EJP64167.1 - 1.4e-38 132.9 0.0 1.9e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EJP64167.1 - 2.4e-06 26.7 0.0 2e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EJP64167.1 - 0.0019 18.9 2.0 0.0035 18.0 2.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 EJP64167.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 EJP64167.1 - 0.16 11.8 0.0 0.45 10.3 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase tRNA-synt_2 PF00152.20 EJP64168.1 - 6.5e-71 239.0 0.0 1e-70 238.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EJP64168.1 - 1e-14 54.2 0.1 1.7e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EJP64168.1 - 1.4e-07 31.4 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain p450 PF00067.22 EJP64169.1 - 2.5e-81 273.8 0.0 3.8e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EJP64169.1 - 6.3e-27 94.6 0.0 1.1e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EJP64169.1 - 3.1e-26 92.3 0.0 6.6e-25 88.0 0.0 2.5 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EJP64169.1 - 7.7e-10 39.4 0.0 3.8e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FMN_red PF03358.15 EJP64169.1 - 0.02 14.7 0.1 1.4 8.7 0.0 2.5 1 1 1 2 2 2 0 NADPH-dependent FMN reductase Ribonucleas_3_3 PF14622.6 EJP64170.1 - 2.8e-11 43.7 0.0 9.8e-05 22.5 0.1 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EJP64170.1 - 8e-05 23.2 0.0 0.0003 21.4 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EJP64170.1 - 0.00032 21.4 0.0 0.00065 20.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Pro_Al_protease PF02983.14 EJP64170.1 - 0.39 10.8 2.6 0.34 11.0 0.2 2.2 2 0 0 2 2 2 0 Alpha-lytic protease prodomain PLA2_B PF01735.18 EJP64171.1 - 3.8e-27 94.9 0.0 3.1e-26 91.8 0.0 2.0 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DUF2722 PF10846.8 EJP64171.1 - 0.17 10.8 5.1 0.32 9.9 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF5363 PF17320.2 EJP64171.1 - 0.29 11.0 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5363) Spt20 PF12090.8 EJP64171.1 - 9.8 5.7 11.9 23 4.5 11.9 1.5 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 EJP64172.1 - 8.8e-42 143.3 0.0 1.4e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64172.1 - 4.3e-23 81.9 0.0 6.3e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EJP64172.1 - 2.5e-06 27.7 0.0 5.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EJP64172.1 - 0.0008 19.7 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Haspin_kinase PF12330.8 EJP64172.1 - 0.06 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EJP64172.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PLDc PF00614.22 EJP64173.1 - 3.6e-15 55.4 1.9 4.5e-08 32.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EJP64173.1 - 1.1e-13 51.2 0.1 5e-05 23.2 0.0 3.8 3 1 0 3 3 3 3 PLD-like domain Spore_coat_CotO PF14153.6 EJP64173.1 - 0.23 11.4 4.6 0.45 10.4 4.6 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF829 PF05705.14 EJP64174.1 - 1.9e-30 106.5 0.0 2.9e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) BRO1 PF03097.18 EJP64175.1 - 8.5e-134 446.2 6.7 8.5e-134 446.2 6.7 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EJP64175.1 - 2.7e-74 250.1 17.9 2.7e-74 250.1 17.9 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV COG2 PF06148.11 EJP64175.1 - 0.3 11.2 6.0 0.29 11.2 1.2 3.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FMN_dh PF01070.18 EJP64176.1 - 3.7e-120 401.1 0.1 4.4e-120 400.9 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EJP64176.1 - 1.4e-22 79.6 0.1 3.1e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EJP64176.1 - 4.4e-07 29.4 0.0 7.2e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EJP64176.1 - 0.0029 16.7 0.2 0.009 15.0 0.1 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EJP64176.1 - 0.042 13.3 0.2 0.063 12.6 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 EJP64176.1 - 0.094 12.2 0.1 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein AAA PF00004.29 EJP64177.1 - 4.6e-11 43.3 0.0 9.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EJP64177.1 - 5.8e-06 26.6 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EJP64177.1 - 8.9e-06 25.8 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EJP64177.1 - 7e-05 22.6 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EJP64177.1 - 8e-05 22.6 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EJP64177.1 - 0.00026 21.4 0.2 0.0015 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EJP64177.1 - 0.0004 20.6 0.9 0.0014 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EJP64177.1 - 0.00044 20.0 1.9 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EJP64177.1 - 0.002 18.1 0.0 0.0047 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EJP64177.1 - 0.015 15.2 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 EJP64177.1 - 0.02 15.4 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF640 PF04852.12 EJP64177.1 - 0.05 13.8 0.0 1.8 8.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF640) AAA_24 PF13479.6 EJP64177.1 - 0.052 13.3 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.19 EJP64177.1 - 0.068 13.8 5.9 3.3 8.4 3.4 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein TsaE PF02367.17 EJP64177.1 - 0.08 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EJP64177.1 - 0.085 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 EJP64177.1 - 0.11 12.0 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EJP64177.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 EJP64177.1 - 0.16 12.3 2.2 0.24 11.7 0.2 2.3 2 1 0 2 2 2 0 AAA domain S4 PF01479.25 EJP64178.1 - 2.5e-15 55.9 0.0 5.3e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EJP64178.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 S4 domain SAT PF16073.5 EJP64178.1 - 0.083 12.6 0.5 0.15 11.8 0.5 1.4 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Fungal_trans PF04082.18 EJP64179.1 - 6.5e-40 136.8 0.1 1.4e-39 135.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64179.1 - 3.9e-08 33.3 6.9 9.5e-08 32.0 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1844 PF08899.11 EJP64179.1 - 0.089 13.1 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) TFIIA PF03153.13 EJP64180.1 - 0.016 15.2 23.3 0.077 13.0 0.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Amidohydro_1 PF01979.20 EJP64181.1 - 4.7e-75 253.0 0.0 5.7e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EJP64181.1 - 5.5e-09 36.0 2.9 1.5e-06 28.0 0.1 2.6 1 1 0 2 2 2 2 Amidohydrolase family Jag_N PF14804.6 EJP64181.1 - 0.053 13.9 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 Jag N-terminus DUF1729 PF08354.10 EJP64182.1 - 4.8e-159 529.0 0.0 7.9e-159 528.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EJP64182.1 - 7.3e-90 301.7 0.0 1.4e-88 297.5 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 EJP64182.1 - 3e-52 176.3 0.0 9.4e-52 174.7 0.0 1.9 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 EJP64182.1 - 3.5e-40 137.0 0.0 1.3e-39 135.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 EJP64182.1 - 5.1e-38 129.4 0.0 1.2e-37 128.2 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 EJP64182.1 - 2.3e-37 129.0 0.0 7.2e-37 127.4 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 EJP64182.1 - 4.5e-25 88.3 0.0 1.6e-24 86.5 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_I_H PF18314.1 EJP64183.1 - 1e-74 250.6 0.0 1e-74 250.6 0.0 2.3 3 0 0 3 3 3 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EJP64183.1 - 9.4e-74 247.1 0.1 3.9e-73 245.1 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EJP64183.1 - 9.9e-23 81.0 0.2 2.6e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EJP64183.1 - 7e-19 68.0 0.1 2.1e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EJP64183.1 - 5.5e-11 42.5 0.0 1.5e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EJP64183.1 - 4.6e-06 26.2 0.0 1.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP64183.1 - 0.00018 21.5 0.2 0.0008 19.4 0.0 2.1 2 0 0 2 2 2 1 KR domain LSM PF01423.22 EJP64184.1 - 4.2e-15 55.2 0.2 5.8e-15 54.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain ANAPC3 PF12895.7 EJP64185.1 - 0.11 12.7 0.1 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EJP64185.1 - 0.12 12.7 0.1 57 4.3 0.0 3.7 4 0 0 4 4 4 0 PPR repeat DUF1487 PF07368.11 EJP64185.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) PPR_2 PF13041.6 EJP64185.1 - 0.2 11.9 0.0 30 4.9 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family MFS_1 PF07690.16 EJP64186.1 - 1.6e-30 106.2 40.2 1.6e-30 106.2 40.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Ku PF02735.16 EJP64188.1 - 3.2e-44 151.1 0.0 8.9e-44 149.6 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EJP64188.1 - 7e-38 130.6 0.0 9.6e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EJP64188.1 - 2.7e-26 92.1 1.0 7e-26 90.8 1.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EJP64188.1 - 2.9e-13 49.2 0.0 5.6e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 EJP64188.1 - 0.02 14.8 0.1 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Ferrochelatase PF00762.19 EJP64189.1 - 1e-97 327.1 0.0 1.2e-97 326.8 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Septin PF00735.18 EJP64190.1 - 5.3e-118 393.4 0.1 5.3e-118 393.4 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EJP64190.1 - 1.5e-08 34.7 0.8 3.9e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJP64190.1 - 1.7e-06 27.7 0.5 0.00028 20.5 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EJP64190.1 - 0.00041 20.9 4.5 0.021 15.3 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EJP64190.1 - 0.0011 18.3 1.5 0.0023 17.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 EJP64190.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EJP64190.1 - 0.0019 18.6 0.2 0.0051 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EJP64190.1 - 0.002 18.1 0.8 0.002 18.1 0.8 3.4 3 1 0 3 3 3 1 RsgA GTPase Ras PF00071.22 EJP64190.1 - 0.0086 15.7 0.0 0.032 13.8 0.0 2.1 1 0 0 1 1 1 1 Ras family AAA_29 PF13555.6 EJP64190.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP64190.1 - 0.018 15.3 1.7 0.031 14.6 0.1 2.3 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EJP64190.1 - 0.053 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 EJP64190.1 - 0.06 13.7 0.8 0.57 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EJP64190.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EJP64190.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EJP64190.1 - 0.094 12.8 8.3 0.84 9.7 0.0 3.4 3 1 0 3 3 3 0 Dynamin family AAA PF00004.29 EJP64190.1 - 0.11 12.9 0.6 3.6 8.0 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 EJP64190.1 - 0.34 10.6 1.9 26 4.5 0.0 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 EJP64190.1 - 0.63 9.6 8.0 0.98 8.9 8.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IIGP PF05049.13 EJP64190.1 - 0.75 8.8 5.2 0.26 10.3 0.2 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AP1AR PF15745.5 EJP64190.1 - 1.9 8.1 9.7 4 7.0 9.7 1.5 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF87 PF01935.17 EJP64190.1 - 7 6.7 7.3 4.4 7.3 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Strep_SA_rep PF06696.11 EJP64190.1 - 7.1 6.7 7.1 2.4 8.2 3.5 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Fis1_TPR_C PF14853.6 EJP64191.1 - 9.1e-25 86.5 1.3 1.5e-24 85.8 1.3 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EJP64191.1 - 8.5e-18 63.7 0.4 1.5e-17 62.9 0.1 1.6 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EJP64191.1 - 0.09 12.9 1.6 0.17 12.1 1.6 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.11 EJP64192.1 - 1.2e-36 125.1 0.5 5.9e-35 119.7 0.0 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 F-box PF00646.33 EJP64194.1 - 2e-06 27.5 0.2 6.8e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EJP64194.1 - 0.00014 21.7 2.5 0.00027 20.8 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 EJP64194.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 F-box OTOS PF15182.6 EJP64194.1 - 0.062 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Otospiralin SBP_bac_6 PF13343.6 EJP64195.1 - 1.5e-12 47.5 0.5 2.2e-09 37.1 0.3 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EJP64195.1 - 2.2e-12 47.4 0.1 3.6e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EJP64195.1 - 2.2e-07 31.2 1.4 1.8e-06 28.2 1.4 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EJP64195.1 - 1.6e-06 28.0 0.0 5.1e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 EJP64195.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain TatD_DNase PF01026.21 EJP64196.1 - 6.8e-30 104.3 0.0 1e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase DUF423 PF04241.15 EJP64197.1 - 0.15 12.3 0.1 0.44 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Fungal_trans PF04082.18 EJP64198.1 - 2.3e-23 82.6 0.3 3.9e-23 81.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64198.1 - 7.9e-08 32.3 9.9 1.4e-07 31.5 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3829 PF12889.7 EJP64198.1 - 0.052 13.0 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) VIR_N PF15912.5 EJP64198.1 - 1.8 8.1 5.0 3.2 7.3 5.0 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Pyridox_oxase_2 PF12766.7 EJP64199.1 - 1.1e-18 67.7 0.1 3.5e-18 66.1 0.1 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DASH_Spc19 PF08287.11 EJP64200.1 - 0.14 12.1 2.8 3.1 7.7 0.2 2.9 2 1 1 3 3 3 0 Spc19 Pkinase PF00069.25 EJP64201.1 - 1.5e-23 83.5 0.0 2.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EJP64201.1 - 2.8e-10 40.6 17.2 7.7e-08 32.9 0.1 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 EJP64201.1 - 6.8e-09 35.2 4.2 0.13 12.6 0.1 6.9 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.17 EJP64201.1 - 2.3e-05 23.8 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EJP64201.1 - 7e-05 23.2 2.9 0.021 15.2 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats Kinase-like PF14531.6 EJP64201.1 - 9.5e-05 21.8 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RTP1_C1 PF10363.9 EJP64201.1 - 0.02 15.1 0.4 0.55 10.4 0.1 3.1 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 ANAPC4_WD40 PF12894.7 EJP64201.1 - 0.058 13.7 0.0 16 5.9 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 EJP64201.1 - 0.089 12.8 0.2 4.8 7.2 0.0 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EJP64201.1 - 0.11 13.0 1.4 61 4.3 0.1 4.4 4 0 0 4 4 4 0 HEAT-like repeat APH PF01636.23 EJP64201.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adaptin_N PF01602.20 EJP64201.1 - 0.14 10.7 0.3 5.8 5.3 0.0 2.6 2 1 0 2 2 2 0 Adaptin N terminal region His_Phos_2 PF00328.22 EJP64203.1 - 2.1e-108 363.1 1.3 3.1e-108 362.6 1.3 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EJP64203.1 - 4.3e-36 122.9 0.1 8.3e-36 122.0 0.1 1.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EJP64203.1 - 8.2e-06 25.5 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 EJP64204.1 - 1.9e-81 273.0 0.0 2.7e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EJP64204.1 - 8.3e-20 70.8 20.4 5.4e-06 27.0 0.5 10.0 11 1 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP64204.1 - 1.7e-12 47.4 0.0 0.13 12.6 0.0 6.4 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EJP64204.1 - 2.3e-06 26.4 0.0 6.4e-06 24.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 EJP64204.1 - 0.0009 18.0 0.2 0.36 9.4 0.0 3.3 3 1 0 3 3 3 1 Nucleoporin Nup120/160 HPS3_N PF14761.6 EJP64204.1 - 0.012 15.2 0.0 0.98 8.9 0.0 2.9 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 Nucleoporin_N PF08801.11 EJP64204.1 - 0.11 11.2 0.0 3.4 6.3 0.0 2.4 1 1 1 2 2 2 0 Nup133 N terminal like Methyltr_RsmB-F PF01189.17 EJP64206.1 - 6.6e-32 110.8 0.4 8.8e-25 87.5 0.0 2.9 4 0 0 4 4 4 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EJP64206.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase GTP1_OBG PF01018.22 EJP64207.1 - 1.2e-41 141.9 1.1 2.2e-30 105.3 4.8 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EJP64207.1 - 6.9e-24 84.1 0.0 1.5e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJP64207.1 - 7e-08 32.1 0.0 3e-07 30.1 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF3245 PF11595.8 EJP64207.1 - 0.0032 18.0 5.6 0.0071 16.8 5.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) ABC_tran PF00005.27 EJP64207.1 - 0.0094 16.5 0.6 0.035 14.6 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 EJP64207.1 - 0.12 12.9 0.4 0.48 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EJP64207.1 - 0.16 11.0 3.1 0.3 10.0 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EJP64207.1 - 0.19 11.1 0.0 0.53 9.7 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Myc_N PF01056.18 EJP64207.1 - 0.99 9.2 3.9 2 8.3 2.1 2.0 2 0 0 2 2 2 0 Myc amino-terminal region FAM176 PF14851.6 EJP64207.1 - 1.4 8.6 4.5 7.2 6.3 4.4 2.0 2 0 0 2 2 2 0 FAM176 family TFIIE-A_C PF11521.8 EJP64207.1 - 3.9 7.9 8.1 2.7 8.3 6.1 1.8 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Serglycin PF04360.12 EJP64208.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Serglycin ABC_tran_CTD PF16326.5 EJP64209.1 - 8e-06 26.0 3.5 8e-06 26.0 3.5 5.6 5 1 0 5 5 5 1 ABC transporter C-terminal domain DUF4239 PF14023.6 EJP64209.1 - 0.16 11.7 9.1 0.058 13.1 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Baculo_PEP_C PF04513.12 EJP64209.1 - 0.3 11.1 6.8 2.3 8.3 0.6 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 EJP64209.1 - 6.2 6.0 13.7 0.36 10.1 8.0 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FlaC_arch PF05377.11 EJP64209.1 - 9.1 6.8 14.2 18 5.8 0.3 4.4 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) RNA_pol_Rpb5_C PF01191.19 EJP64210.1 - 7.4e-32 109.0 0.2 2.6e-31 107.3 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EJP64210.1 - 1.1e-26 93.2 0.0 1.7e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EJP64210.1 - 0.029 14.4 0.0 0.091 12.8 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease COX2_TM PF02790.15 EJP64211.1 - 0.094 12.9 0.6 0.31 11.2 0.6 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain TFCD_C PF12612.8 EJP64212.1 - 4e-27 95.3 0.4 2.2e-26 92.9 0.4 2.4 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EJP64212.1 - 0.0025 17.9 4.1 0.9 10.0 0.0 6.1 5 1 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EJP64212.1 - 0.0082 16.5 8.3 2 8.8 0.1 5.1 6 0 0 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EJP64212.1 - 0.029 15.0 0.0 0.2 12.3 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EJP64212.1 - 0.43 9.6 5.6 1.1 8.3 0.2 3.1 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Glyco_hydro_76 PF03663.14 EJP64213.1 - 1.4e-45 156.4 2.2 1.4e-45 156.4 2.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EJP64213.1 - 6.3e-05 22.2 0.7 0.026 13.6 0.0 2.5 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 EJP64213.1 - 0.0032 17.0 0.0 0.071 12.6 0.0 2.5 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 EJP64213.1 - 0.0043 15.6 0.1 0.067 11.7 0.0 2.0 1 1 1 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Glyco_transf_17 PF04724.13 EJP64214.1 - 9.4e-44 149.9 0.0 2.1e-43 148.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF4943 PF16301.5 EJP64214.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4943) SH3_9 PF14604.6 EJP64215.1 - 2.5e-09 36.8 0.9 1.2e-08 34.6 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EJP64215.1 - 0.21 11.3 2.0 0.52 10.0 2.0 1.7 1 0 0 1 1 1 0 SH3 domain Anoctamin PF04547.12 EJP64216.1 - 5.5e-112 374.9 10.2 6.6e-112 374.6 10.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 EJP64216.1 - 0.058 13.1 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Pro-kuma_activ PF09286.11 EJP64217.1 - 4.5e-39 134.0 1.2 1.4e-38 132.4 0.7 2.1 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP64217.1 - 1.5e-06 27.7 3.0 1.5e-05 24.4 2.7 2.2 2 0 0 2 2 2 1 Subtilase family Ish1 PF10281.9 EJP64217.1 - 0.065 13.5 0.1 23 5.4 0.1 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF3485 PF11984.8 EJP64217.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) Metallophos PF00149.28 EJP64218.1 - 2.5e-11 44.5 1.0 4.4e-11 43.7 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP64218.1 - 1.1e-05 25.6 2.4 9.1e-05 22.7 2.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain YhhN PF07947.14 EJP64219.1 - 5.1e-36 124.0 15.7 8.5e-36 123.3 15.7 1.3 1 0 0 1 1 1 1 YhhN family WSC PF01822.19 EJP64220.1 - 1.7e-13 50.5 7.6 6e-13 48.8 7.6 2.0 1 0 0 1 1 1 1 WSC domain Glyco_hydro_16 PF00722.21 EJP64220.1 - 3.6e-05 23.3 0.0 0.00014 21.4 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pex2_Pex12 PF04757.14 EJP64221.1 - 1.3e-53 182.0 6.6 1.7e-53 181.5 6.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EJP64221.1 - 0.0019 18.3 2.8 0.0036 17.4 2.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EJP64221.1 - 0.013 15.9 3.2 0.022 15.1 3.2 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 EJP64221.1 - 0.018 14.9 2.2 0.028 14.3 2.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mucin PF01456.17 EJP64221.1 - 0.018 15.0 24.2 0.035 14.1 24.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 EJP64221.1 - 0.022 12.8 2.9 0.029 12.4 2.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C3HC4_2 PF13923.6 EJP64221.1 - 0.033 14.0 3.3 0.063 13.1 3.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP64221.1 - 0.11 12.3 2.7 0.21 11.5 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Patatin PF01734.22 EJP64221.1 - 0.19 11.9 0.9 0.5 10.5 0.9 1.7 2 0 0 2 2 2 0 Patatin-like phospholipase zf-RING_UBOX PF13445.6 EJP64221.1 - 0.25 11.4 1.8 0.46 10.6 1.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF1955 PF09205.10 EJP64221.1 - 0.28 10.9 0.0 0.5 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Tir_receptor_C PF07489.11 EJP64221.1 - 0.9 9.5 8.9 1.4 8.8 8.9 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus AJAP1_PANP_C PF15298.6 EJP64221.1 - 1.3 9.3 9.8 2 8.6 9.8 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus FSA_C PF10479.9 EJP64221.1 - 3.1 5.8 4.9 4.5 5.3 4.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sporozoite_P67 PF05642.11 EJP64221.1 - 4.7 5.2 5.6 6.2 4.8 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen 4HBT PF03061.22 EJP64222.1 - 3.3e-12 46.6 0.0 4.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EJP64222.1 - 7.4e-05 23.1 0.0 9.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 EJP64222.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) V-ATPase_H_N PF03224.14 EJP64222.1 - 0.22 10.8 0.0 0.23 10.7 0.0 1.0 1 0 0 1 1 1 0 V-ATPase subunit H APH PF01636.23 EJP64223.1 - 4.6e-11 43.1 1.9 9e-11 42.2 0.6 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family F-box-like PF12937.7 EJP64223.1 - 7.3e-06 25.8 0.0 1.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP64223.1 - 8.1e-06 25.6 0.4 2.6e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 F-box domain DUF1679 PF07914.11 EJP64223.1 - 0.0026 16.7 0.0 0.0036 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EJP64223.1 - 0.05 12.9 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase F-box_4 PF15966.5 EJP64223.1 - 0.15 11.9 0.1 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 F-box Fungal_trans PF04082.18 EJP64224.1 - 1.8e-60 204.2 0.0 2.7e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EJP64224.1 - 2.5e-07 30.8 10.3 0.0026 18.1 0.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP64224.1 - 0.0034 18.1 16.3 0.053 14.4 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger SAP30_Sin3_bdg PF13867.6 EJP64225.1 - 4.5e-08 33.3 0.1 2e-07 31.2 0.1 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DnaJ_C PF01556.18 EJP64226.1 - 2.7e-38 131.4 0.0 3.8e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJP64226.1 - 1.5e-23 82.7 2.0 3.5e-23 81.5 2.0 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EJP64226.1 - 1.2e-09 38.4 20.5 2.2e-09 37.6 20.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EJP64226.1 - 0.016 15.2 3.2 0.016 15.2 3.2 3.0 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ PF00226.31 EJP64227.1 - 1.9e-13 50.3 0.3 1.9e-13 50.3 0.3 2.8 3 0 0 3 3 3 1 DnaJ domain ALMT PF11744.8 EJP64227.1 - 0.82 8.4 3.4 0.89 8.3 3.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Jak1_Phl PF17887.1 EJP64227.1 - 8.3 6.4 11.4 0.69 9.9 6.5 1.7 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain Carbam_trans_C PF16861.5 EJP64228.1 - 3.3e-69 231.8 0.0 5.4e-69 231.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 EJP64228.1 - 4.1e-62 210.8 0.0 5.3e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Peptidase_M22 PF00814.25 EJP64228.1 - 0.00089 19.0 0.0 0.57 9.8 0.0 2.3 2 0 0 2 2 2 2 Glycoprotease family DEAD PF00270.29 EJP64229.1 - 9.3e-49 165.6 0.3 6.6e-48 162.8 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP64229.1 - 1.4e-24 86.6 3.0 8.5e-24 84.0 0.1 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EJP64229.1 - 6.8e-21 74.3 5.1 6.8e-21 74.3 5.1 2.2 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.15 EJP64229.1 - 8e-07 29.2 0.0 2.6e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FNIP_N PF14636.6 EJP64230.1 - 8.3e-40 137.3 2.8 8.3e-40 137.3 2.8 5.1 4 3 0 4 4 4 1 Folliculin-interacting protein N-terminus APH PF01636.23 EJP64231.1 - 1.3e-14 54.7 0.0 2.6e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP64231.1 - 1.9e-05 24.3 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EJP64231.1 - 0.0081 15.8 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.14 EJP64231.1 - 0.02 14.3 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EJP64231.1 - 0.13 11.6 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64231.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Cation_efflux PF01545.21 EJP64232.1 - 6.1e-51 173.0 7.2 8.4e-51 172.5 7.2 1.2 1 0 0 1 1 1 1 Cation efflux family IML1 PF12257.8 EJP64233.1 - 4.5e-116 386.9 0.0 6.6e-116 386.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EJP64233.1 - 1.7e-24 85.6 0.0 5.6e-24 84.0 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PEX-2N PF09263.10 EJP64233.1 - 0.16 12.3 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal DUF4027 PF13219.6 EJP64233.1 - 2.5 8.0 4.8 2.2 8.2 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4027) PhyH PF05721.13 EJP64234.1 - 1.3e-25 90.9 0.0 1.7e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HGWP PF03578.15 EJP64234.1 - 0.023 14.2 0.1 0.052 13.1 0.1 1.6 1 0 0 1 1 1 0 HGWP repeat Fungal_trans_2 PF11951.8 EJP64235.1 - 1.1e-25 90.3 0.9 5.3e-13 48.5 0.1 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64235.1 - 1e-07 31.9 7.1 1.7e-07 31.3 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Enterotoxin_a PF01375.17 EJP64236.1 - 2.2e-20 73.4 0.0 5e-20 72.2 0.0 1.5 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain adh_short_C2 PF13561.6 EJP64237.1 - 7.9e-62 208.9 4.1 9.1e-62 208.7 4.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP64237.1 - 2.4e-49 167.4 2.9 3e-49 167.1 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EJP64237.1 - 0.024 14.5 0.3 0.042 13.7 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 EJP64238.1 - 5.4e-40 137.4 24.5 7e-40 137.0 24.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP64238.1 - 3.9e-09 35.9 14.8 3.9e-09 35.9 14.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Gcn1_N PF12074.8 EJP64239.1 - 1.2e-110 370.2 12.0 1.2e-110 370.2 12.0 3.5 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 EJP64239.1 - 1.8e-59 199.9 7.6 4.4e-59 198.7 7.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_EZ PF13513.6 EJP64239.1 - 6.3e-35 119.2 50.8 3.7e-08 33.7 0.1 20.7 17 4 9 26 26 24 8 HEAT-like repeat HEAT PF02985.22 EJP64239.1 - 4.2e-31 104.3 40.3 0.17 12.2 0.1 22.7 26 0 0 26 26 25 7 HEAT repeat HEAT_2 PF13646.6 EJP64239.1 - 3.1e-24 85.2 48.2 9.9e-05 22.7 0.0 14.5 10 4 5 15 15 15 10 HEAT repeats Cnd1 PF12717.7 EJP64239.1 - 1.6e-14 54.3 6.8 1.9 8.5 0.0 11.1 8 3 2 11 11 11 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EJP64239.1 - 2.4e-14 53.7 0.0 2.7 8.6 0.0 10.0 8 2 2 10 10 8 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 EJP64239.1 - 2e-10 41.1 1.5 6.5e-05 23.1 0.0 5.7 5 1 2 7 7 6 1 Parkin co-regulated protein CLASP_N PF12348.8 EJP64239.1 - 1.3e-09 37.9 0.0 0.056 13.0 0.0 6.0 6 0 0 6 6 6 3 CLASP N terminal UME PF08064.13 EJP64239.1 - 3.3e-09 36.6 0.6 7.2 6.6 0.0 8.2 7 1 1 8 8 8 1 UME (NUC010) domain DUF937 PF06078.11 EJP64239.1 - 6.5e-06 26.8 8.3 1.3 9.7 0.0 6.7 8 1 0 8 8 5 2 Bacterial protein of unknown function (DUF937) RasGEF_N_2 PF14663.6 EJP64239.1 - 0.00065 20.1 1.8 15 6.1 0.0 5.9 6 0 0 6 6 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MMS19_C PF12460.8 EJP64239.1 - 0.00078 18.7 28.1 0.02 14.0 0.1 9.2 9 2 2 12 12 12 2 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 EJP64239.1 - 0.00097 17.8 23.0 0.042 12.4 2.3 8.3 9 2 2 11 11 11 1 Adaptin N terminal region TIP120 PF08623.10 EJP64239.1 - 0.0015 18.3 5.2 0.39 10.5 0.0 6.5 7 1 1 8 8 7 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 EJP64239.1 - 0.0016 18.4 0.0 5.5 6.9 0.0 5.9 6 2 0 6 6 6 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 EJP64239.1 - 0.0017 18.0 0.5 5.6 6.4 0.0 6.3 6 1 0 6 6 6 1 Tti2 family TFCD_C PF12612.8 EJP64239.1 - 0.0047 16.8 0.2 0.091 12.6 0.1 3.3 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal Dopey_N PF04118.14 EJP64239.1 - 0.012 14.7 1.6 23 3.9 0.0 5.8 6 2 1 7 7 7 0 Dopey, N-terminal RIX1 PF08167.12 EJP64239.1 - 0.056 13.2 8.3 0.18 11.5 0.3 5.3 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis FANCI_S2 PF14676.6 EJP64239.1 - 0.082 13.2 4.4 2.9 8.2 0.1 4.5 5 0 0 5 5 4 0 FANCI solenoid 2 Ecm29 PF13001.7 EJP64239.1 - 0.24 10.0 13.9 4.9 5.7 0.0 6.3 7 1 0 7 7 7 0 Proteasome stabiliser SHMT PF00464.19 EJP64240.1 - 2.7e-193 642.0 0.0 3.2e-193 641.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EJP64240.1 - 0.077 12.3 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EJP64240.1 - 0.084 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 2OG-FeII_Oxy_2 PF13532.6 EJP64241.1 - 6.5e-28 98.3 0.1 1.1e-27 97.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EJP64241.1 - 6.9e-19 68.7 0.1 1.3e-18 67.8 0.1 1.5 1 0 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 EJP64241.1 - 4.5e-06 26.6 0.0 9.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EJP64241.1 - 0.00052 20.2 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP64241.1 - 0.00099 19.3 0.0 0.0037 17.4 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TAF8_C PF10406.9 EJP64242.1 - 3.6e-18 65.9 0.2 8.2e-18 64.7 0.2 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EJP64242.1 - 1.3e-09 37.9 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated WD40 PF00400.32 EJP64243.1 - 2e-46 155.0 23.5 1.1e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP64243.1 - 1.7e-09 37.8 0.5 0.044 14.1 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP64243.1 - 9.3e-05 21.3 4.9 0.052 12.2 0.1 4.2 1 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EJP64243.1 - 0.0015 17.6 0.0 7.7 5.4 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EJP64243.1 - 0.0062 15.9 0.0 0.68 9.2 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain PD40 PF07676.12 EJP64243.1 - 0.01 15.7 0.2 23 5.1 0.0 4.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat OST3_OST6 PF04756.13 EJP64244.1 - 2.4e-94 316.0 0.0 3.1e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Csm1_N PF18504.1 EJP64245.1 - 0.0038 17.5 1.1 0.0038 17.5 1.1 5.7 1 1 5 6 6 5 1 Csm1 N-terminal domain GAS PF13851.6 EJP64245.1 - 0.0043 16.4 37.9 0.036 13.4 2.2 3.4 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding USP8_interact PF08941.10 EJP64245.1 - 0.028 14.2 16.7 0.29 10.9 4.9 2.8 2 1 1 3 3 3 0 USP8 interacting Atg14 PF10186.9 EJP64245.1 - 0.05 12.7 35.7 4e+03 -3.4 35.7 2.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 EJP64245.1 - 0.11 13.0 35.9 3.1 8.2 17.8 2.5 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.9 EJP64245.1 - 0.18 11.2 38.3 0.062 12.8 11.7 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 EJP64245.1 - 0.24 11.4 35.3 2.8 8.0 1.3 4.3 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.11 EJP64245.1 - 0.29 11.0 19.1 0.24 11.2 0.8 3.1 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) HMMR_N PF15905.5 EJP64245.1 - 0.4 10.1 36.1 0.09 12.2 23.5 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 EJP64245.1 - 0.65 10.4 22.8 1 9.8 1.7 5.4 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) EzrA PF06160.12 EJP64245.1 - 0.76 7.9 26.0 1.7 6.7 10.3 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF730 PF05325.11 EJP64245.1 - 0.78 9.8 7.0 1.7 8.7 2.0 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF730) Filament PF00038.21 EJP64245.1 - 0.87 9.1 36.1 0.7 9.4 3.8 3.3 1 1 2 3 3 3 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 EJP64245.1 - 1.1 9.3 43.1 4.5 7.3 6.7 4.4 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.11 EJP64245.1 - 1.1 7.8 34.6 0.51 9.0 26.6 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.11 EJP64245.1 - 1.4 7.7 36.2 5 5.9 25.9 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 EJP64245.1 - 2.2 6.8 26.0 1.5 7.4 6.0 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 EJP64245.1 - 4.4 8.0 38.7 4 8.1 14.5 4.2 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 EJP64245.1 - 5.2 7.4 29.8 5.5 7.3 15.6 3.2 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 EJP64245.1 - 7.7 6.0 34.6 0.84 9.1 17.0 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DivIC PF04977.15 EJP64245.1 - 9.4 6.1 28.1 3.5 7.5 0.6 5.0 2 2 1 4 4 4 0 Septum formation initiator Ribosomal_L18 PF17135.4 EJP64246.1 - 5.7e-90 299.7 4.7 7.9e-90 299.3 4.7 1.2 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Mito_carr PF00153.27 EJP64246.1 - 2.1e-70 232.7 3.1 1.7e-22 79.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJP64246.1 - 0.00051 19.3 0.2 0.0084 15.3 0.0 2.7 2 1 1 3 3 3 1 Gammaproteobacterial serine protease Ribosomal_L27A PF00828.19 EJP64246.1 - 0.003 18.2 0.3 0.01 16.5 0.3 2.0 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RRM_1 PF00076.22 EJP64247.1 - 0.00062 19.5 0.0 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPR3 PF03666.13 EJP64247.1 - 3.3 6.4 9.1 4.4 6.0 9.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NOA36 PF06524.12 EJP64247.1 - 4.1 6.6 15.0 5.7 6.2 15.0 1.2 1 0 0 1 1 1 0 NOA36 protein MBOAT PF03062.19 EJP64248.1 - 0.00013 21.5 3.7 0.00019 20.9 3.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family LXG PF04740.12 EJP64248.1 - 0.07 12.8 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Pex14_N PF04695.13 EJP64248.1 - 0.099 13.3 0.1 0.12 13.0 0.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region dUTPase_2 PF08761.11 EJP64248.1 - 0.099 12.8 0.2 0.48 10.6 0.1 1.9 2 0 0 2 2 2 0 dUTPase CH PF00307.31 EJP64249.1 - 7.3e-68 225.6 0.0 8.3e-18 64.6 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EJP64249.1 - 9.7e-06 26.0 0.5 8.7e-05 22.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 EJP64249.1 - 0.018 14.9 0.0 10 6.0 0.0 3.8 4 0 0 4 4 4 0 CAMSAP CH domain EF-hand_6 PF13405.6 EJP64249.1 - 0.11 12.5 0.6 3.7 7.7 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EJP64249.1 - 0.12 12.0 0.6 27 4.6 0.1 3.4 3 0 0 3 3 3 0 EF hand DDHD PF02862.17 EJP64250.1 - 2.6e-55 188.0 3.9 3.3e-54 184.4 0.0 2.7 3 0 0 3 3 3 1 DDHD domain zf-RING_2 PF13639.6 EJP64250.1 - 0.05 13.9 2.6 0.15 12.4 2.6 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 EJP64250.1 - 0.19 11.6 1.4 0.6 10.0 0.5 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LIDHydrolase PF10230.9 EJP64250.1 - 0.2 11.2 0.1 0.86 9.1 0.0 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase AbfB PF05270.13 EJP64251.1 - 0.039 13.9 0.0 3 7.8 0.0 2.1 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase B (ABFB) domain HR1 PF02185.16 EJP64253.1 - 0.023 14.8 0.1 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 Hr1 repeat Exonuc_VII_L PF02601.15 EJP64253.1 - 0.026 14.1 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mod_r PF07200.13 EJP64253.1 - 0.072 13.2 0.5 5.5 7.1 0.1 2.5 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Lsr2 PF11774.8 EJP64253.1 - 0.088 13.0 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Lsr2 Occludin_ELL PF07303.13 EJP64254.1 - 1.1 10.0 5.5 14 6.5 0.7 2.6 2 0 0 2 2 2 0 Occludin homology domain Bacillus_HBL PF05791.11 EJP64255.1 - 0.00016 21.5 4.0 0.00018 21.4 0.8 2.3 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.12 EJP64255.1 - 0.017 15.1 0.3 0.075 13.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4515 PF14988.6 EJP64255.1 - 0.072 12.9 0.4 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Strep_SA_rep PF06696.11 EJP64255.1 - 1 9.5 3.2 0.79 9.8 0.9 2.0 2 0 0 2 2 2 0 Streptococcal surface antigen repeat MFS_1 PF07690.16 EJP64257.1 - 3.3e-13 49.3 43.6 3.3e-13 49.3 43.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 EJP64257.1 - 0.21 10.6 0.0 0.4 9.6 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Peptidase_M41 PF01434.18 EJP64258.1 - 8.7e-68 227.9 0.0 1.7e-67 227.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EJP64258.1 - 6.3e-42 143.1 0.0 6.6e-41 139.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP64258.1 - 4.3e-13 48.8 0.1 1.2e-12 47.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EJP64258.1 - 1e-08 35.5 0.0 2.5e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 EJP64258.1 - 0.0011 19.0 0.0 0.0051 16.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EJP64258.1 - 0.0031 16.8 0.1 0.0075 15.5 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EJP64258.1 - 0.0067 16.6 0.0 0.1 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EJP64258.1 - 0.016 15.6 0.4 0.58 10.5 0.1 2.9 2 1 1 3 3 3 0 AAA ATPase domain RuvB_N PF05496.12 EJP64258.1 - 0.017 14.9 0.1 0.085 12.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EJP64258.1 - 0.017 15.4 0.5 1.5 9.1 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 EJP64258.1 - 0.078 13.4 0.0 0.32 11.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EJP64258.1 - 0.11 12.2 0.1 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EJP64258.1 - 0.11 12.6 0.0 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Methyltransf_31 PF13847.6 EJP64259.1 - 1.3e-07 31.5 0.0 2.4e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP64259.1 - 1.3e-07 31.3 0.0 3.7e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_10 PF05971.12 EJP64259.1 - 1.8e-05 24.2 0.0 2.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_25 PF13649.6 EJP64259.1 - 3.5e-05 24.4 0.0 7.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 EJP64259.1 - 0.00042 19.7 0.0 0.0006 19.2 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_23 PF13489.6 EJP64259.1 - 0.00084 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EJP64259.1 - 0.0009 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 EJP64259.1 - 0.0062 16.0 0.1 0.04 13.4 0.1 1.9 1 1 1 2 2 2 1 RRNA methyltransferase AviRa PrmC_N PF17827.1 EJP64259.1 - 0.0078 16.8 0.8 0.0078 16.8 0.8 1.9 2 0 0 2 2 2 1 PrmC N-terminal domain Ubie_methyltran PF01209.18 EJP64259.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EJP64259.1 - 0.069 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EJP64259.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EJP64259.1 - 0.15 11.8 0.2 0.64 9.7 0.2 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 CAGE1 PF15066.6 EJP64259.1 - 0.29 9.8 0.4 0.42 9.2 0.4 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family MAPEG PF01124.18 EJP64260.1 - 9.1e-16 58.0 1.0 1.1e-15 57.7 1.0 1.0 1 0 0 1 1 1 1 MAPEG family RNA_pol_L_2 PF13656.6 EJP64261.1 - 1.5e-20 72.7 0.1 1.9e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EJP64261.1 - 4.1e-06 26.1 0.0 2.5e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LSM PF01423.22 EJP64262.1 - 1.5e-22 79.0 0.1 1.7e-22 78.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EJP64262.1 - 0.04 14.1 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain DNA_pol_A_exo1 PF01612.20 EJP64263.1 - 1.9e-11 44.0 0.0 2.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease NLE PF08154.12 EJP64264.1 - 1.2e-14 54.5 0.1 1.9e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 EJP64264.1 - 1.2e-13 51.3 6.0 0.071 14.0 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat G-patch PF01585.23 EJP64265.1 - 1.4e-11 44.1 1.0 2.6e-11 43.2 1.0 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EJP64265.1 - 4.3e-06 26.5 3.1 0.0018 18.1 0.1 3.4 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 EJP64265.1 - 8.7e-06 25.7 1.2 8.7e-06 25.7 1.2 2.3 2 0 0 2 2 2 1 G-patch domain zf-RanBP PF00641.18 EJP64265.1 - 5.3e-05 22.5 2.6 0.00012 21.3 2.6 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RED_N PF07808.13 EJP64265.1 - 0.0061 16.2 1.4 0.0061 16.2 1.4 3.5 4 1 1 5 5 5 1 RED-like protein N-terminal region zf-C2H2_2 PF12756.7 EJP64265.1 - 0.084 13.2 0.1 0.084 13.2 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Vps36-NZF-N PF16988.5 EJP64265.1 - 1.6 8.2 6.5 2.5 7.6 3.5 2.7 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MoaE PF02391.17 EJP64266.1 - 2.5e-36 124.4 0.0 3.1e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Asp PF00026.23 EJP64268.1 - 1.7e-63 215.0 0.0 2.5e-62 211.1 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP64268.1 - 1.1e-13 51.8 0.8 7.5e-10 39.3 0.6 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP64268.1 - 0.00042 20.9 0.6 0.67 10.6 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EJP64268.1 - 0.08 13.5 0.0 6.5 7.4 0.0 3.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease 4HBT_3 PF13622.6 EJP64269.1 - 4.8e-77 259.6 4.2 6.1e-77 259.2 4.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EJP64269.1 - 9.7e-24 83.7 0.0 1e-11 44.8 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Succ_CoA_lig PF13607.6 EJP64269.1 - 0.11 12.3 0.0 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Oxysterol_BP PF01237.18 EJP64270.1 - 4.7e-133 443.6 1.1 5.1e-132 440.2 0.0 2.7 3 0 0 3 3 3 1 Oxysterol-binding protein Ank_2 PF12796.7 EJP64270.1 - 1.3e-14 54.5 0.1 1.4e-09 38.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP64270.1 - 3.9e-14 52.8 1.1 4.3e-09 36.7 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP64270.1 - 4.9e-14 52.2 0.1 1.5e-06 28.3 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP64270.1 - 5.4e-14 50.9 0.3 0.00012 22.2 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EJP64270.1 - 2e-12 47.0 2.8 0.0011 19.3 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.29 EJP64270.1 - 2.5e-12 47.2 0.6 5.8e-12 46.1 0.6 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EJP64270.1 - 9.6e-08 32.2 0.6 2.5e-07 30.9 0.6 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EJP64270.1 - 1.1e-05 25.8 1.3 3.8e-05 24.0 1.3 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain SRR1 PF07985.12 EJP64271.1 - 8.8e-10 38.5 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 SRR1 E2F_CC-MB PF16421.5 EJP64271.1 - 0.031 14.6 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain PALB2_WD40 PF16756.5 EJP64271.1 - 0.056 12.4 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Osmo_CC PF08946.10 EJP64271.1 - 1.5 9.1 4.1 13 6.2 0.3 3.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DUF4813 PF16072.5 EJP64272.1 - 1.8 8.1 6.3 3.1 7.4 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Thioredoxin PF00085.20 EJP64273.1 - 1.7e-07 31.2 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 EJP64273.1 - 0.0012 18.4 0.0 0.0031 17.1 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.10 EJP64273.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.6 EJP64273.1 - 0.026 15.0 0.0 0.059 13.8 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EJP64273.1 - 0.052 13.7 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like MFS_1 PF07690.16 EJP64274.1 - 3.1e-37 128.3 34.5 3.4e-27 95.3 12.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP64274.1 - 8.7e-11 41.3 10.6 8.7e-11 41.3 10.6 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EJP64274.1 - 6.1e-05 21.6 4.3 0.00012 20.7 4.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ELP6 PF09807.9 EJP64275.1 - 2.5e-06 27.1 0.0 4.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Elongation complex protein 6 RCDG1 PF15725.5 EJP64275.1 - 1.5 9.3 6.2 3.7 8.0 5.5 2.0 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Ribosomal_L37e PF01907.19 EJP64276.1 - 1.2e-26 92.6 10.2 1.8e-26 92.1 10.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EJP64276.1 - 0.01 15.9 1.1 0.015 15.3 1.1 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 EJP64276.1 - 0.011 15.6 2.2 0.017 15.0 2.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 EJP64276.1 - 0.013 15.5 0.9 0.018 15.1 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_5 PF14634.6 EJP64276.1 - 0.026 14.5 1.4 0.04 13.9 1.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 EJP64276.1 - 0.043 13.2 1.0 0.064 12.7 1.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 EJP64276.1 - 0.047 13.6 2.1 0.069 13.0 2.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP64276.1 - 0.13 12.1 2.6 0.22 11.4 2.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 EJP64276.1 - 0.24 11.2 2.6 2.7 7.8 3.1 2.1 1 1 2 3 3 3 0 zinc-ribbon domain OPT PF03169.15 EJP64277.1 - 3e-179 597.6 45.6 3.5e-179 597.4 45.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EIAV_GP90 PF00971.18 EJP64277.1 - 0.26 9.9 2.2 0.7 8.5 0.1 2.2 2 0 0 2 2 2 0 EIAV coat protein, gp90 GST_N_3 PF13417.6 EJP64278.1 - 6.8e-08 32.8 0.0 1.7e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP64278.1 - 0.00078 19.4 0.0 0.0075 16.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EJP64278.1 - 0.08 13.3 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EJP64278.1 - 0.11 12.3 0.0 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PP-binding PF00550.25 EJP64279.1 - 6.9e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 EJP64279.1 - 9.5e-06 24.5 0.0 1.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Aminotran_5 PF00266.19 EJP64280.1 - 2.8e-09 36.4 0.0 2.9e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V CENP-F_leu_zip PF10473.9 EJP64281.1 - 0.017 15.1 0.4 0.32 11.0 0.2 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3874 PF12990.7 EJP64281.1 - 0.034 14.5 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) EF-hand_2 PF09068.11 EJP64281.1 - 0.049 13.8 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 EF hand Fib_alpha PF08702.10 EJP64281.1 - 0.06 13.5 0.2 0.11 12.6 0.1 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CEP209_CC5 PF16574.5 EJP64281.1 - 0.093 12.9 0.5 0.12 12.6 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 TPR_6 PF13174.6 EJP64281.1 - 0.22 12.2 3.7 35 5.3 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat SlyX PF04102.12 EJP64281.1 - 0.75 10.5 2.9 0.46 11.1 0.5 2.0 2 2 0 2 2 2 0 SlyX DUF4208 PF13907.6 EJP64282.1 - 0.077 13.4 0.7 0.25 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) UQ_con PF00179.26 EJP64283.1 - 6.2e-31 106.9 0.0 8.2e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EJP64283.1 - 0.051 13.9 0.2 0.11 12.7 0.2 1.6 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 EJP64283.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 YL1 PF05764.13 EJP64283.1 - 0.11 12.5 9.4 0.14 12.3 9.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein AA_permease PF00324.21 EJP64284.1 - 8.8e-128 426.9 35.1 1e-127 426.7 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP64284.1 - 1.9e-33 116.0 37.7 2.8e-33 115.4 37.7 1.2 1 0 0 1 1 1 1 Amino acid permease HGTP_anticodon2 PF12745.7 EJP64285.1 - 6.3e-79 265.2 0.2 6.3e-79 265.2 0.2 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EJP64285.1 - 8.5e-74 248.2 0.0 7.6e-38 130.4 0.0 3.7 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64285.1 - 1.2e-45 155.8 0.0 2.1e-22 79.6 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 EJP64285.1 - 1.9e-18 66.8 0.0 1.9e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 EJP64285.1 - 3.6e-12 46.6 0.1 9e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 RWD domain APH PF01636.23 EJP64285.1 - 0.13 12.2 4.9 0.15 12.0 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family Zn_clus PF00172.18 EJP64286.1 - 0.00069 19.7 10.0 0.0014 18.7 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EJP64287.1 - 7.2e-10 38.7 0.0 2.3e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64287.1 - 8.6e-08 31.8 0.0 3.5e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EJP64287.1 - 2.9e-05 24.1 0.3 0.015 15.2 0.3 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP64287.1 - 0.00072 19.2 0.1 0.2 11.2 0.1 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase Kdo PF06293.14 EJP64287.1 - 0.0035 16.7 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.27 EJP64288.1 - 5e-73 241.1 1.2 2.3e-23 81.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJP64288.1 - 0.03 13.5 0.7 0.18 10.9 0.0 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Glyco_hydro_16 PF00722.21 EJP64289.1 - 3.5e-11 42.9 0.0 7.1e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EJP64289.1 - 0.012 14.0 0.1 0.022 13.2 0.1 1.3 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) FAF PF11250.8 EJP64289.1 - 0.24 11.7 0.0 0.24 11.7 0.0 2.5 2 0 0 2 2 2 0 Fantastic Four meristem regulator OTT_1508_deam PF14441.6 EJP64290.1 - 4.2e-17 61.9 2.0 9.3e-17 60.8 2.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase SMC_ScpA PF02616.14 EJP64290.1 - 0.074 12.9 0.3 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Segregation and condensation protein ScpA FMO-like PF00743.19 EJP64291.1 - 1.3e-09 37.0 0.0 2.1e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP64291.1 - 5.7e-09 35.7 4.2 1.2e-07 31.3 3.3 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP64291.1 - 9.3e-09 34.9 1.6 2e-06 27.2 0.6 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP64291.1 - 2.9e-05 24.2 0.2 2.9e-05 24.2 0.2 3.0 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP64291.1 - 0.00036 21.0 0.1 0.071 13.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP64291.1 - 0.00078 18.7 0.0 0.45 9.7 0.1 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 EJP64291.1 - 0.0094 15.6 2.5 0.15 11.6 1.4 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP64291.1 - 0.051 12.6 1.3 6.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EJP64291.1 - 0.1 11.6 4.5 0.62 9.1 2.8 2.7 3 0 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 EJP64291.1 - 0.19 12.2 0.0 0.65 10.5 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.6 EJP64291.1 - 0.48 9.5 1.7 0.95 8.5 0.0 2.3 4 0 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EJP64291.1 - 0.89 8.6 3.2 1.1 8.2 0.9 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Oxidored_FMN PF00724.20 EJP64292.1 - 9.7e-41 140.1 0.0 1.3e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans_2 PF11951.8 EJP64293.1 - 4.8e-12 45.4 0.1 2.1e-11 43.3 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64293.1 - 5e-09 36.1 9.4 9.2e-09 35.3 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PolyA_pol PF01743.20 EJP64294.1 - 5.3e-13 49.5 0.1 1.3e-12 48.3 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EJP64294.1 - 2.7e-05 23.9 0.1 7e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A NAD_binding_2 PF03446.15 EJP64296.1 - 4.9e-32 111.3 0.0 1e-31 110.3 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EJP64296.1 - 1.4e-14 54.3 1.1 2.7e-14 53.4 1.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 EJP64296.1 - 0.00024 20.5 0.0 0.0031 16.9 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EJP64296.1 - 0.0071 16.9 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PaaX_C PF08223.11 EJP64296.1 - 0.037 14.3 0.1 5.3 7.4 0.0 2.3 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Sacchrp_dh_NADP PF03435.18 EJP64296.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-C2H2 PF00096.26 EJP64297.1 - 0.12 12.9 0.3 0.29 11.7 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type APH PF01636.23 EJP64298.1 - 4.6e-09 36.6 0.0 1.6e-08 34.8 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family zf-C4H2 PF10146.9 EJP64299.1 - 5.2 7.3 19.3 0.39 11.0 1.0 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein LpoB PF13036.6 EJP64300.1 - 0.0034 17.3 3.9 0.0034 17.3 3.9 1.6 2 0 0 2 2 2 1 Peptidoglycan-synthase activator LpoB TFIIA PF03153.13 EJP64300.1 - 0.15 12.1 18.0 0.21 11.5 18.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EJP64300.1 - 0.4 10.3 10.5 0.65 9.6 10.5 1.4 1 0 0 1 1 1 0 Spt20 family DUF702 PF05142.12 EJP64300.1 - 8.6 6.8 10.4 21 5.6 9.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF702) DUF3433 PF11915.8 EJP64301.1 - 1.3e-30 105.6 18.8 1.3e-27 96.1 4.0 4.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) DUF1996 PF09362.10 EJP64302.1 - 2.4e-66 224.1 0.5 2.9e-66 223.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF4449 PF14613.6 EJP64303.1 - 2.7e-07 30.8 0.3 2.7e-07 30.8 0.3 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) SDH_sah PF01972.16 EJP64303.1 - 0.11 11.5 0.2 0.25 10.3 0.2 1.6 1 0 0 1 1 1 0 Serine dehydrogenase proteinase HisK_N PF09385.10 EJP64303.1 - 0.16 11.9 2.3 5.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Histidine kinase N terminal DUF445 PF04286.12 EJP64303.1 - 1.4 8.7 11.8 4.5 7.0 10.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) PEP-utilisers_N PF05524.13 EJP64303.1 - 6.8 6.9 8.5 7.4 6.8 1.8 3.8 3 2 1 4 4 4 0 PEP-utilising enzyme, N-terminal Pirin PF02678.16 EJP64304.1 - 2.9e-24 85.1 1.2 7.1e-24 83.9 1.2 1.6 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EJP64304.1 - 0.0003 20.4 2.0 0.0074 16.0 0.7 2.9 2 1 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 EJP64304.1 - 0.029 14.6 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain DIOX_N PF14226.6 EJP64305.1 - 3.4e-22 79.4 0.0 5.4e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EJP64305.1 - 1.3e-12 48.1 0.0 3.8e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 EJP64305.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DNA_ligase_A_M PF01068.21 EJP64306.1 - 2.4e-23 82.8 0.0 5.1e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EJP64306.1 - 2.2e-18 67.2 0.0 1e-17 65.0 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 EJP64306.1 - 3.2e-07 30.8 0.0 9e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 RNA ligase SOG2 PF10428.9 EJP64306.1 - 4.6 6.3 22.4 7.9 5.6 22.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein RNB PF00773.19 EJP64307.1 - 7.8e-76 255.5 0.0 1.5e-75 254.5 0.0 1.5 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 EJP64307.1 - 7.9e-26 90.2 0.0 3.5e-25 88.1 0.0 2.2 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 EJP64307.1 - 1.1e-25 89.5 0.0 2.4e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EJP64307.1 - 1.5e-05 25.0 0.0 0.022 14.9 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EJP64307.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Rrp44-like cold shock domain DUF4239 PF14023.6 EJP64307.1 - 0.38 10.4 0.9 0.77 9.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) NPR3 PF03666.13 EJP64307.1 - 1.6 7.5 11.1 0.046 12.5 2.2 2.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 GLE1 PF07817.13 EJP64308.1 - 1.1e-57 195.2 0.0 1.5e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein UPF0242 PF06785.11 EJP64308.1 - 0.44 10.6 6.2 1.1 9.3 6.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 EJP64309.1 - 6e-25 87.7 0.3 4.7e-24 84.8 0.0 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EJP64309.1 - 1.6e-05 24.8 0.7 3.6e-05 23.7 0.7 1.6 1 0 0 1 1 1 1 SNARE domain DUF3348 PF11828.8 EJP64309.1 - 0.0057 16.4 5.3 0.0068 16.1 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3348) ArAE_2_N PF10337.9 EJP64309.1 - 0.032 13.3 0.2 0.042 12.9 0.2 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal T3SS_needle_F PF09392.10 EJP64309.1 - 0.072 13.3 1.2 12 6.2 0.0 3.5 3 1 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Methyltransf_32 PF13679.6 EJP64310.1 - 8.6e-22 77.8 0.0 1.6e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ACT_7 PF13840.6 EJP64311.1 - 6.4e-20 70.7 0.1 4e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 ACT domain UPF0029 PF01205.19 EJP64312.1 - 1.8e-32 111.8 0.0 3.5e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EJP64312.1 - 0.0028 17.9 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain Ribosomal_60s PF00428.19 EJP64312.1 - 0.61 10.7 9.5 1.1 9.9 9.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_A4 PF01828.17 EJP64313.1 - 3.8e-55 186.6 1.9 5.2e-55 186.1 1.9 1.2 1 0 0 1 1 1 1 Peptidase A4 family Lsr2 PF11774.8 EJP64313.1 - 0.0073 16.4 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Lsr2 ATP-synt_ab PF00006.25 EJP64314.1 - 3.2e-107 357.0 0.0 4.5e-107 356.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EJP64314.1 - 2.4e-33 114.6 0.2 5.6e-31 106.9 0.2 2.6 1 1 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EJP64314.1 - 9.4e-13 48.5 1.4 2.5e-12 47.1 1.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain F_actin_bind PF08919.10 EJP64314.1 - 0.034 14.2 0.1 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 F-actin binding ArgJ PF01960.18 EJP64315.1 - 2.8e-149 497.0 0.6 3.2e-149 496.8 0.6 1.0 1 0 0 1 1 1 1 ArgJ family Metallophos PF00149.28 EJP64316.1 - 1.1e-14 55.4 1.2 1.9e-14 54.6 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase baeRF_family10 PF18854.1 EJP64317.1 - 0.048 13.9 1.7 0.59 10.4 0.1 2.5 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 10 Pro-kuma_activ PF09286.11 EJP64318.1 - 1.3e-36 126.0 0.1 2.6e-36 125.0 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP64318.1 - 1.5e-05 24.4 0.2 2.6e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Subtilase family Pet127 PF08634.10 EJP64319.1 - 6.8e-121 402.9 1.6 1.4e-120 401.9 1.6 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DUF2543 PF10820.8 EJP64319.1 - 0.092 12.9 0.2 0.092 12.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2543) Hid1 PF12722.7 EJP64320.1 - 2.8e-284 945.3 0.0 3.2e-284 945.1 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EJP64320.1 - 1.4e-98 331.0 0.0 1.5e-98 330.9 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Sec8_exocyst PF04048.14 EJP64321.1 - 1.1e-46 158.2 0.1 3.1e-46 156.8 0.1 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EJP64321.1 - 1.4e-10 41.0 0.2 3.1e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex YcbB PF08664.10 EJP64321.1 - 0.097 12.7 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 YcbB domain FUSC PF04632.12 EJP64321.1 - 0.15 10.6 2.8 0.29 9.6 2.8 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EJP64321.1 - 1.9 7.9 5.5 0.51 9.9 0.9 2.3 2 1 0 2 2 2 0 Exonuclease VII, large subunit SMI1_KNR4 PF09346.10 EJP64322.1 - 1.4e-31 109.7 0.1 3.1e-31 108.5 0.1 1.6 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Glyco_hydro_61 PF03443.14 EJP64324.1 - 2.2e-05 24.5 0.1 4.2e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 EJP64324.1 - 2.6e-05 25.0 0.0 6.1e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GGACT PF06094.12 EJP64325.1 - 4.5e-19 69.2 0.0 5.7e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EJP64325.1 - 0.016 15.6 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 AIG2-like family COesterase PF00135.28 EJP64327.1 - 2.5e-74 251.0 0.0 3.4e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EJP64327.1 - 0.0033 17.3 0.1 0.028 14.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PD40 PF07676.12 EJP64327.1 - 0.046 13.7 0.3 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat UvdE PF03851.14 EJP64328.1 - 4.2e-112 373.9 0.0 5.4e-112 373.5 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Pectate_lyase_3 PF12708.7 EJP64333.1 - 1.1e-67 228.1 20.3 1.6e-65 221.0 4.4 4.0 4 1 1 5 5 5 2 Pectate lyase superfamily protein adh_short PF00106.25 EJP64334.1 - 4.1e-14 52.5 0.6 4.5e-12 45.8 0.6 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP64334.1 - 8.2e-05 22.3 0.0 0.00081 19.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GRDP-like PF07173.12 EJP64335.1 - 9.3e-17 62.0 5.2 9.4e-14 52.3 0.6 3.0 2 1 0 2 2 2 2 Glycine-rich domain-containing protein-like Raptor_N PF14538.6 EJP64336.1 - 3.9e-65 218.3 0.0 7.5e-65 217.4 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EJP64336.1 - 9.5e-07 29.4 1.8 3.5 8.6 0.0 6.2 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 EJP64336.1 - 6.1e-05 23.0 0.1 0.24 11.5 0.1 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.6 EJP64336.1 - 0.0063 16.9 0.4 1.4 9.3 0.0 3.7 4 0 0 4 4 4 1 HEAT repeats Atx10homo_assoc PF09759.9 EJP64336.1 - 0.035 14.1 1.0 0.066 13.2 1.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain PaaX_C PF08223.11 EJP64336.1 - 0.21 11.9 0.1 0.21 11.9 0.1 2.9 3 0 0 3 3 3 0 PaaX-like protein C-terminal domain tRNA-synt_2 PF00152.20 EJP64337.1 - 1.8e-67 227.7 0.0 2.2e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJP64337.1 - 7.3e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.8 EJP64337.1 - 2.1 7.2 7.8 3 6.6 7.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 bZIP_1 PF00170.21 EJP64339.1 - 4.4e-07 29.9 14.1 7.9e-07 29.1 14.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 EJP64339.1 - 4.5e-06 26.7 14.0 0.00029 20.7 0.0 2.3 2 0 0 2 2 2 1 Transcription factor PAP1 SHE3 PF17078.5 EJP64339.1 - 0.0036 17.1 10.1 0.0052 16.5 10.1 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 EJP64339.1 - 0.016 15.7 12.6 0.016 15.7 12.6 2.9 1 1 2 3 3 3 0 bZIP Maf transcription factor bZIP_2 PF07716.15 EJP64339.1 - 0.091 12.9 16.6 0.23 11.6 15.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 EJP64339.1 - 0.95 9.8 4.9 4.8 7.6 1.0 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family Exonuc_VII_L PF02601.15 EJP64339.1 - 5.5 6.5 13.9 9.1 5.7 13.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EJP64339.1 - 7.8 4.3 21.2 0.16 9.9 13.4 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CDP-OH_P_transf PF01066.21 EJP64340.1 - 4e-18 65.9 0.1 4e-18 65.9 0.1 3.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase SUR7 PF06687.12 EJP64342.1 - 9.4e-19 67.9 13.0 1.3e-18 67.4 13.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family MSP1a PF11670.8 EJP64342.1 - 0.0079 15.5 0.2 0.0079 15.5 0.2 1.7 2 0 0 2 2 2 1 Major surface protein 1a (MSP1a) DUF2207 PF09972.9 EJP64342.1 - 0.61 8.8 4.1 1.1 8.0 4.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 EJP64342.1 - 1.6 8.5 5.9 3.1 7.5 5.9 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2070 PF09843.9 EJP64342.1 - 8.2 4.6 11.2 12 4.0 11.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC_tran PF00005.27 EJP64343.1 - 3.3e-45 154.0 0.0 1.8e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP64343.1 - 1.7e-24 86.9 21.1 6.3e-21 75.2 12.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_22 PF13401.6 EJP64343.1 - 2.6e-06 27.8 0.9 0.047 14.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EJP64343.1 - 3e-06 27.2 0.3 0.0023 17.8 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EJP64343.1 - 6.6e-06 26.6 0.1 0.022 15.2 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EJP64343.1 - 7.2e-06 25.7 1.2 0.068 12.9 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EJP64343.1 - 7.8e-06 25.9 0.0 0.14 12.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP64343.1 - 0.00038 20.0 1.4 5 6.5 0.1 3.7 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP64343.1 - 0.00054 20.5 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EJP64343.1 - 0.001 18.6 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EJP64343.1 - 0.0012 19.0 0.1 0.71 10.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EJP64343.1 - 0.0019 17.6 0.1 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SSE PF00437.20 EJP64343.1 - 0.0021 17.2 0.3 0.38 9.8 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 EJP64343.1 - 0.015 15.4 4.7 0.039 14.1 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_15 PF13175.6 EJP64343.1 - 0.021 14.5 0.9 8.4 6.0 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain NB-ARC PF00931.22 EJP64343.1 - 0.037 13.2 0.0 0.51 9.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 EJP64343.1 - 0.046 13.9 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EJP64343.1 - 0.051 13.5 1.3 0.19 11.6 0.1 2.3 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_25 PF13481.6 EJP64343.1 - 0.069 12.7 0.2 6.7 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EJP64343.1 - 0.1 13.0 0.1 18 5.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 EJP64343.1 - 0.11 12.4 0.9 8.7 6.3 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EJP64343.1 - 0.14 12.7 0.0 8 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EJP64343.1 - 0.19 12.2 0.2 4.1 7.8 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UCR_UQCRX_QCR9 PF05365.12 EJP64343.1 - 1.6 8.7 6.0 1.9 8.5 0.7 3.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like p450 PF00067.22 EJP64344.1 - 1.7e-53 182.0 0.0 2.2e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FeS_assembly_P PF01883.19 EJP64344.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein AMP-binding PF00501.28 EJP64345.1 - 0 1020.0 2.7 2.7e-79 266.7 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 EJP64345.1 - 1.5e-167 557.9 0.0 8e-48 163.2 0.0 4.7 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 EJP64345.1 - 4.9e-48 161.4 9.7 8.6e-10 38.8 0.1 6.1 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP64345.1 - 0.00018 22.4 0.0 2.3 9.3 0.0 4.7 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain Ribosomal_L34e PF01199.18 EJP64345.1 - 0.066 13.5 0.0 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L34e WES_acyltransf PF03007.16 EJP64345.1 - 1.2 8.8 11.4 11 5.7 0.1 4.6 5 0 0 5 5 5 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Menin PF05053.13 EJP64345.1 - 5.3 5.3 6.0 8.7 4.6 6.0 1.2 1 0 0 1 1 1 0 Menin RXT2_N PF08595.11 EJP64345.1 - 8.5 6.4 6.0 43 4.1 0.1 3.7 4 0 0 4 4 4 0 RXT2-like, N-terminal ABC1 PF03109.16 EJP64346.1 - 2.4e-20 72.9 0.0 6e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EJP64346.1 - 2.9e-05 24.1 0.2 7.1e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Septin PF00735.18 EJP64347.1 - 4.5e-29 101.6 0.0 2.7e-12 46.5 0.0 3.1 3 0 0 3 3 3 3 Septin AAA_23 PF13476.6 EJP64347.1 - 0.0091 16.5 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 EJP64347.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3313 PF11769.8 EJP64347.1 - 0.11 12.3 0.3 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3313) Myb_DNA-binding PF00249.31 EJP64350.1 - 4.4e-15 55.6 1.0 1.2e-07 31.8 0.1 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP64350.1 - 1.6e-11 44.2 0.3 7.3e-06 26.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EJP64350.1 - 1.6e-06 28.1 0.4 0.023 14.7 0.0 3.0 2 1 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EJP64350.1 - 0.021 15.0 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Apt1 PF10351.9 EJP64350.1 - 1.4 7.7 12.1 2.3 7.0 12.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain MAJIN PF15077.6 EJP64350.1 - 3.1 7.5 12.1 1.6 8.5 1.1 2.5 2 0 0 2 2 2 0 Membrane-anchored junction protein Ribosomal_S4e PF00900.20 EJP64351.1 - 2.3e-37 126.7 0.2 5.6e-37 125.5 0.2 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EJP64351.1 - 1.8e-23 81.9 0.1 3.2e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EJP64351.1 - 7.6e-19 67.5 4.2 1.5e-18 66.6 4.2 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EJP64351.1 - 8.7e-06 25.4 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EJP64351.1 - 1.5e-05 24.8 1.2 1.5e-05 24.8 1.2 3.1 4 0 0 4 4 4 1 KOW motif FAD-oxidase_C PF02913.19 EJP64352.1 - 3.5e-61 207.0 0.0 5.1e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EJP64352.1 - 4.3e-35 120.5 0.0 9.2e-35 119.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 EJP64352.1 - 0.13 10.9 0.1 0.21 10.2 0.1 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RdRP PF05183.12 EJP64353.1 - 5.8e-87 292.7 0.0 9e-87 292.1 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase hnRNP_Q_AcD PF18360.1 EJP64353.1 - 0.01 15.8 0.1 0.044 13.8 0.1 2.1 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain RdRP PF05183.12 EJP64354.1 - 6.6e-82 276.0 0.0 8.3e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Avian_gp85 PF03708.14 EJP64354.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 2OG-FeII_Oxy_3 PF13640.6 EJP64355.1 - 1.1e-11 45.5 0.0 2.4e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pex14_N PF04695.13 EJP64356.1 - 0.16 12.6 6.3 0.23 12.1 6.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5102 PF17104.5 EJP64356.1 - 1.6 8.7 4.6 2.1 8.3 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Fumble PF03630.14 EJP64357.1 - 6.1e-139 462.8 0.0 1e-138 462.1 0.0 1.3 1 1 0 1 1 1 1 Fumble SSP160 PF06933.11 EJP64357.1 - 1.7 6.7 7.8 2.3 6.3 7.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-H2C2_2 PF13465.6 EJP64358.1 - 0.019 15.4 3.0 0.037 14.5 1.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain SID-1_RNA_chan PF13965.6 EJP64359.1 - 0.0077 14.7 0.6 0.01 14.3 0.6 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DDHD PF02862.17 EJP64359.1 - 0.15 12.2 12.0 0.36 11.0 12.0 1.7 1 0 0 1 1 1 0 DDHD domain CSG2 PF16965.5 EJP64359.1 - 0.73 8.7 9.1 1.2 7.9 9.1 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Sugar_tr PF00083.24 EJP64359.1 - 0.9 8.3 2.3 1.3 7.8 2.3 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter MAJIN PF15077.6 EJP64359.1 - 0.94 9.2 15.7 1.8 8.3 15.7 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein EOS1 PF12326.8 EJP64359.1 - 2 8.3 6.2 4.3 7.2 6.2 1.5 1 0 0 1 1 1 0 N-glycosylation protein SUFU_C PF12470.8 EJP64359.1 - 2.1 8.3 12.8 4.6 7.3 12.8 1.6 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Connexin PF00029.19 EJP64359.1 - 2.4 7.8 11.4 5.3 6.7 11.4 1.6 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 EJP64359.1 - 2.5 7.9 21.3 4.6 7.0 21.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.11 EJP64359.1 - 6 5.2 17.0 8.5 4.7 17.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 EJP64359.1 - 7 4.8 48.4 9.6 4.3 48.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 EJP64359.1 - 7.4 6.5 16.3 14 5.7 16.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4228 PF14009.6 EJP64359.1 - 9.7 6.5 9.0 16 5.9 8.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) HET PF06985.11 EJP64360.1 - 1.2e-05 25.7 5.0 0.0014 19.0 0.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SpdB PF05122.13 EJP64360.1 - 0.21 11.8 4.7 4.3 7.5 5.8 2.5 2 0 0 2 2 2 0 Mobile element transfer protein GPHR_N PF12537.8 EJP64361.1 - 2.5 8.3 4.3 0.43 10.7 0.4 1.7 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal RGS PF00615.19 EJP64362.1 - 0.00012 22.4 0.1 0.0078 16.5 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pox_A14 PF05767.12 EJP64362.1 - 0.093 12.9 0.7 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Redoxin PF08534.10 EJP64363.1 - 2.2e-34 118.3 0.1 2.5e-34 118.1 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EJP64363.1 - 9.9e-10 38.4 0.0 1.2e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family NaeI PF09126.10 EJP64363.1 - 0.15 11.2 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 Restriction endonuclease NaeI Ribosomal_L24e PF01246.20 EJP64364.1 - 3.4e-28 97.6 0.2 8e-28 96.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e A_deamin PF02137.18 EJP64365.1 - 2.6e-33 115.9 0.0 3.1e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NAC PF01849.18 EJP64366.1 - 2.9e-22 78.4 1.1 8.3e-22 76.9 0.3 1.9 2 0 0 2 2 2 1 NAC domain Glyco_hydro_18 PF00704.28 EJP64367.1 - 1.3e-74 251.7 1.7 1.6e-74 251.5 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ABC_tran PF00005.27 EJP64369.1 - 2.1e-43 148.1 0.0 7.4e-22 78.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP64369.1 - 8.6e-26 91.2 15.6 2.4e-16 60.2 6.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP64369.1 - 9.2e-15 54.7 3.7 1.6e-05 24.5 2.2 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP64369.1 - 6.5e-08 32.7 4.4 0.037 13.8 0.5 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP64369.1 - 2e-07 30.6 0.5 0.015 15.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJP64369.1 - 4e-06 26.9 0.3 0.21 11.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EJP64369.1 - 5e-06 27.0 0.1 0.17 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EJP64369.1 - 5.5e-06 26.7 4.2 0.029 14.6 0.1 3.6 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EJP64369.1 - 7.7e-06 25.9 0.0 0.012 15.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EJP64369.1 - 1.1e-05 26.0 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EJP64369.1 - 9.5e-05 22.8 0.0 0.063 13.7 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EJP64369.1 - 0.00068 19.0 0.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 EJP64369.1 - 0.00093 19.0 0.0 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EJP64369.1 - 0.0013 18.0 0.1 0.41 9.8 0.1 3.1 2 1 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 EJP64369.1 - 0.0032 17.5 1.5 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 EJP64369.1 - 0.0033 17.0 2.2 0.057 13.0 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EJP64369.1 - 0.0037 16.8 0.0 3.1 7.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 EJP64369.1 - 0.0051 16.8 0.3 1.5 8.9 0.0 3.4 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EJP64369.1 - 0.0074 16.0 1.0 3.5 7.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EJP64369.1 - 0.0091 15.9 0.9 14 5.6 0.0 3.5 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.9 EJP64369.1 - 0.011 15.5 0.2 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 EJP64369.1 - 0.011 14.8 0.0 0.62 9.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EJP64369.1 - 0.014 15.4 0.0 6.5 6.6 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 EJP64369.1 - 0.015 14.9 0.0 0.34 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EJP64369.1 - 0.02 15.4 0.0 0.57 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EJP64369.1 - 0.02 14.6 1.1 14 5.4 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF87 PF01935.17 EJP64369.1 - 0.022 14.9 0.1 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 EJP64369.1 - 0.028 14.6 0.5 0.94 9.8 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 EJP64369.1 - 0.031 13.1 0.3 0.81 8.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Roc PF08477.13 EJP64369.1 - 0.055 13.7 0.5 7 6.9 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EJP64369.1 - 0.055 12.6 0.1 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EJP64369.1 - 0.067 12.8 1.5 6.7 6.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.17 EJP64369.1 - 0.076 12.8 0.1 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 EJP64369.1 - 0.085 12.2 0.0 0.76 9.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 EJP64369.1 - 0.093 12.7 0.3 53 3.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EJP64369.1 - 0.14 12.1 1.0 9.8 6.1 0.0 2.7 3 0 0 3 3 2 0 NACHT domain AAA_24 PF13479.6 EJP64369.1 - 0.16 11.7 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EJP64369.1 - 0.28 11.4 1.1 2 8.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain CBP4 PF07960.11 EJP64370.1 - 2.6e-22 79.1 3.4 4.3e-22 78.3 3.4 1.3 1 1 0 1 1 1 1 CBP4 Receptor_IA-2 PF11548.8 EJP64370.1 - 0.074 13.0 0.2 1.5 8.8 0.5 2.1 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 PilN PF05137.13 EJP64370.1 - 0.075 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) 4HB_MCP_1 PF12729.7 EJP64370.1 - 0.081 12.5 2.3 0.1 12.1 2.3 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction KOG2701 PF09762.9 EJP64370.1 - 0.19 11.9 4.0 0.26 11.5 4.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Sel1 PF08238.12 EJP64371.1 - 7.7e-41 137.6 23.3 1.8e-07 31.6 0.1 8.4 8 0 0 8 8 8 7 Sel1 repeat Yae1_N PF09811.9 EJP64371.1 - 1.2 8.9 12.5 0.25 11.1 8.0 2.3 2 0 0 2 2 2 0 Essential protein Yae1, N terminal FAD_binding_4 PF01565.23 EJP64373.1 - 1.1e-28 99.8 0.9 2.2e-28 98.7 0.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP64373.1 - 1.7e-07 31.2 0.0 3.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like GFO_IDH_MocA PF01408.22 EJP64374.1 - 3e-18 66.8 0.5 3e-18 66.8 0.5 2.2 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EJP64374.1 - 3.9e-05 23.6 0.2 0.00017 21.6 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain ApbA PF02558.16 EJP64374.1 - 0.0055 16.4 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EJP64374.1 - 0.083 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 EJP64374.1 - 0.098 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.16 EJP64375.1 - 2.5e-15 56.3 41.5 3.8e-15 55.7 39.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EJP64375.1 - 9.3e-14 51.4 7.7 9.3e-14 51.4 7.7 2.2 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Cation_ATPase_C PF00689.21 EJP64376.1 - 2.2e-42 144.8 8.0 2.2e-42 144.8 8.0 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EJP64376.1 - 2e-40 138.3 1.6 2e-40 138.3 1.6 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EJP64376.1 - 8.6e-21 73.8 0.0 2.1e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EJP64376.1 - 9.6e-20 71.8 0.1 8.5e-09 36.0 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EJP64376.1 - 5.1e-13 48.5 0.0 1.4e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP64376.1 - 0.00037 20.3 0.1 0.00091 19.0 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP64376.1 - 0.078 13.4 0.0 9.2 6.6 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Nucleos_tra2_N PF01773.20 EJP64376.1 - 1.3 9.7 7.9 20 5.9 0.4 3.8 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus zf-C2H2 PF00096.26 EJP64379.1 - 8.4e-09 35.4 11.5 0.00012 22.4 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP64379.1 - 3.6e-08 33.6 9.6 0.00069 20.2 0.8 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EJP64379.1 - 1.9e-06 28.1 13.1 4.7e-06 26.8 1.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EJP64379.1 - 0.00066 19.6 5.6 0.11 12.5 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger BolA PF01722.18 EJP64379.1 - 0.001 19.3 3.1 0.36 11.1 0.0 3.0 2 1 1 3 3 3 2 BolA-like protein zf-MYST PF17772.1 EJP64379.1 - 0.023 14.3 0.9 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 MYST family zinc finger domain zf-CHY PF05495.12 EJP64379.1 - 0.22 12.0 7.1 2.7 8.5 7.2 2.4 1 1 0 1 1 1 0 CHY zinc finger zf-C2H2_jaz PF12171.8 EJP64379.1 - 0.6 10.5 0.1 0.6 10.5 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TFIIA PF03153.13 EJP64379.1 - 1.3 8.9 26.9 1.8 8.5 26.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_11 PF16622.5 EJP64379.1 - 3.1 7.6 6.9 10 6.0 1.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EJP64379.1 - 5.6 7.5 9.0 9.8 6.7 1.6 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 EJP64379.1 - 8.3 6.7 10.4 25 5.1 2.6 2.7 1 1 1 2 2 2 0 AN1-like Zinc finger Ctr PF04145.15 EJP64380.1 - 1.6e-31 109.9 0.2 1.9e-31 109.7 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SRF-TF PF00319.18 EJP64381.1 - 4.6e-21 74.0 0.1 6.4e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Tetraspanin PF00335.20 EJP64382.1 - 1.1e-05 25.2 5.5 2.3e-05 24.2 5.7 1.4 1 1 0 1 1 1 1 Tetraspanin family Mg_trans_NIPA PF05653.14 EJP64383.1 - 1.2e-13 50.9 12.2 1.9e-13 50.2 12.2 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EJP64383.1 - 9.4e-05 22.6 16.2 0.0018 18.4 0.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EJP64383.1 - 0.00025 20.4 1.9 0.00025 20.4 1.9 2.5 1 1 2 3 3 3 1 Purine nucleobase transmembrane transport vATP-synt_E PF01991.18 EJP64384.1 - 1.9e-64 216.8 14.7 2.2e-64 216.6 14.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FliH PF02108.16 EJP64384.1 - 0.0076 16.3 3.3 0.025 14.6 1.9 2.6 1 1 1 2 2 2 1 Flagellar assembly protein FliH Methyltransf_7 PF03492.15 EJP64384.1 - 0.033 13.4 2.9 0.22 10.7 3.1 1.9 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase DNA_repr_REX1B PF14966.6 EJP64385.1 - 0.12 13.1 0.0 0.87 10.3 0.0 2.3 3 0 0 3 3 3 0 DNA repair REX1-B Presenilin PF01080.17 EJP64386.1 - 0.075 11.8 1.2 0.093 11.5 1.2 1.1 1 0 0 1 1 1 0 Presenilin FAM220 PF15487.6 EJP64386.1 - 7.4 6.1 11.6 13 5.3 11.6 1.3 1 0 0 1 1 1 0 FAM220 family PhoLip_ATPase_C PF16212.5 EJP64387.1 - 1.4e-75 254.3 22.9 1.4e-75 254.3 22.9 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EJP64387.1 - 6.4e-20 70.6 0.2 1.5e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EJP64387.1 - 6.2e-13 48.7 0.0 3.7e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EJP64387.1 - 3.7e-09 37.2 0.2 2.1e-05 24.9 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EJP64387.1 - 0.0079 15.7 0.0 0.0079 15.7 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EJP64387.1 - 0.017 14.9 0.5 0.038 13.7 0.5 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Legionella_OMP PF05150.12 EJP64387.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Aldedh PF00171.22 EJP64388.1 - 1.4e-120 402.9 0.3 1.8e-120 402.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.29 EJP64389.1 - 3.3e-44 150.7 0.0 4.9e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP64389.1 - 7.2e-26 90.7 0.0 2.7e-25 88.9 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EJP64389.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.15 EJP64389.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ipi1_N PF12333.8 EJP64390.1 - 2.3e-27 95.6 0.0 2.3e-27 95.6 0.0 2.2 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.17 EJP64391.1 - 6.2e-08 32.3 0.2 7.6e-05 22.4 0.0 2.2 1 1 1 2 2 2 2 Roadblock/LC7 domain UPF0139 PF03669.13 EJP64392.1 - 8.7e-07 28.7 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) S1-P1_nuclease PF02265.16 EJP64395.1 - 7.2e-72 242.2 0.5 8.2e-72 242.0 0.5 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease TPR_12 PF13424.6 EJP64396.1 - 2.4e-34 117.5 12.6 2.5e-09 37.3 0.8 6.2 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 EJP64396.1 - 4.3e-30 102.7 14.3 3.5e-05 23.5 0.1 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP64396.1 - 4.1e-18 65.8 5.6 1.5e-08 34.4 0.1 3.2 1 1 0 3 3 3 3 MalT-like TPR region TPR_2 PF07719.17 EJP64396.1 - 3.4e-16 58.0 16.3 0.0018 18.2 0.7 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EJP64396.1 - 1.7e-15 56.1 10.3 0.0011 18.7 0.0 7.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EJP64396.1 - 7.7e-13 48.1 17.8 0.43 11.5 0.0 8.6 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EJP64396.1 - 4.8e-12 45.1 9.4 0.014 15.6 0.3 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP64396.1 - 8.4e-09 34.9 10.1 0.22 11.6 0.0 7.4 8 0 0 8 8 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 EJP64396.1 - 3.8e-08 32.8 0.1 1.8e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 NB-ARC domain TPR_16 PF13432.6 EJP64396.1 - 7.9e-08 32.8 6.7 0.0021 18.6 0.1 6.0 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 EJP64396.1 - 9.4e-08 32.0 6.4 0.21 12.3 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 EJP64396.1 - 6.1e-07 30.0 0.1 1.6e-06 28.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.6 EJP64396.1 - 7.1e-07 29.6 11.4 0.54 10.8 1.0 6.1 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJP64396.1 - 0.0002 21.5 2.1 2.1 8.9 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ATPase_2 PF01637.18 EJP64396.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PPR PF01535.20 EJP64396.1 - 0.0011 19.1 0.6 9.4 6.7 0.0 5.1 4 0 0 4 4 4 0 PPR repeat TPR_6 PF13174.6 EJP64396.1 - 0.0032 18.0 19.2 0.22 12.2 0.1 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat AAA_22 PF13401.6 EJP64396.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EJP64396.1 - 0.1 12.8 0.0 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain HET PF06985.11 EJP64396.1 - 0.16 12.3 1.4 0.33 11.3 0.4 2.1 2 0 0 2 2 1 0 Heterokaryon incompatibility protein (HET) TadE PF07811.12 EJP64396.1 - 0.72 10.2 2.7 24 5.3 0.0 3.3 3 0 0 3 3 3 0 TadE-like protein PQ-loop PF04193.14 EJP64397.1 - 1.7e-37 127.0 14.2 7.8e-21 73.6 0.3 3.1 3 0 0 3 3 3 2 PQ loop repeat Methyltransf_23 PF13489.6 EJP64397.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Semialdhyde_dhC PF02774.18 EJP64398.1 - 2.6e-39 135.2 0.0 3.3e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EJP64398.1 - 5.4e-29 101.1 0.0 1.4e-28 99.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EJP64398.1 - 0.12 13.1 0.0 0.31 11.8 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GPI2 PF06432.11 EJP64400.1 - 2.1e-134 447.3 0.1 2.7e-134 447.0 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase HET PF06985.11 EJP64401.1 - 4e-09 37.0 4.5 4.8e-07 30.2 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Med31 PF05669.12 EJP64402.1 - 3.7e-35 119.8 1.7 6.3e-35 119.1 1.7 1.4 1 0 0 1 1 1 1 SOH1 CFEM PF05730.11 EJP64402.1 - 4.2e-12 46.0 10.6 6.6e-12 45.3 10.6 1.3 1 0 0 1 1 1 1 CFEM domain TFIIS_C PF01096.18 EJP64403.1 - 1.6e-19 69.4 1.4 1.6e-19 69.4 1.4 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EJP64403.1 - 1.1e-07 31.6 2.6 1.7e-07 31.0 0.3 2.3 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EJP64403.1 - 0.00073 19.5 7.0 0.054 13.5 1.1 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain IBR PF01485.21 EJP64403.1 - 0.0011 19.1 7.1 0.22 11.8 1.4 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain Desulfoferrod_N PF06397.12 EJP64403.1 - 0.0044 16.6 1.1 0.92 9.2 0.1 2.4 2 0 0 2 2 2 2 Desulfoferrodoxin, N-terminal domain Zn_ribbon_recom PF13408.6 EJP64403.1 - 0.026 15.0 4.2 0.028 14.9 0.4 2.5 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-RING_12 PF17976.1 EJP64403.1 - 0.19 12.0 3.4 0.37 11.1 0.1 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain OrfB_Zn_ribbon PF07282.11 EJP64403.1 - 1.2 9.1 6.0 14 5.7 0.0 2.5 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Zn_ribbon_SprT PF17283.2 EJP64403.1 - 1.5 8.8 6.9 0.87 9.6 1.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 EJP64403.1 - 2.9 7.9 12.0 3.7 7.5 0.2 3.8 3 1 1 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.6 EJP64403.1 - 3.3 7.7 10.3 0.66 10.0 1.5 2.9 3 0 0 3 3 3 0 Nudix N-terminal UPF0547 PF10571.9 EJP64403.1 - 7.3 6.8 12.5 4.6 7.4 0.4 3.3 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 Ank_3 PF13606.6 EJP64404.1 - 2e-08 33.8 0.1 0.0063 16.9 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EJP64404.1 - 6.9e-07 29.7 0.1 1.4e-05 25.5 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP64404.1 - 1.2e-06 29.0 0.0 5.1e-06 27.0 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EJP64404.1 - 5.7e-05 23.4 0.0 0.19 12.2 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EJP64404.1 - 8.8e-05 22.7 0.2 2.1 8.8 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) TetR_C_31 PF17940.1 EJP64404.1 - 0.037 14.2 1.4 0.86 9.8 0.2 2.8 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain EF-1_beta_acid PF10587.9 EJP64404.1 - 7.6 7.1 8.7 3.9 8.0 5.9 1.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Thaumatin PF00314.17 EJP64405.1 - 2.2e-66 223.6 5.0 3.9e-66 222.7 5.0 1.4 1 0 0 1 1 1 1 Thaumatin family HSP70 PF00012.20 EJP64405.1 - 1.4e-09 36.7 0.2 2.2e-08 32.8 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EJP64405.1 - 0.12 11.2 0.1 0.48 9.2 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein Hexokinase_2 PF03727.16 EJP64406.1 - 1e-78 264.1 0.0 1.5e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EJP64406.1 - 8.6e-74 247.7 0.0 1.3e-73 247.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Pam17 PF08566.10 EJP64406.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Syntaxin-6_N PF09177.11 EJP64406.1 - 0.19 12.3 0.1 0.53 10.9 0.0 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Acetyltransf_1 PF00583.25 EJP64407.1 - 4.3e-07 30.2 0.0 6.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP64407.1 - 0.021 15.2 0.0 0.032 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP64407.1 - 0.2 11.6 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2732 PF10809.8 EJP64408.1 - 0.088 12.7 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) zf_UBZ PF18439.1 EJP64408.1 - 1.2 8.7 6.0 1.8 8.2 0.3 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 EJP64408.1 - 1.3 8.7 7.9 0.15 11.6 3.1 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF3246 PF11596.8 EJP64408.1 - 5.5 6.3 7.8 0.31 10.5 2.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Pro_isomerase PF00160.21 EJP64409.1 - 1.4e-52 178.1 0.0 1.6e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 EJP64410.1 - 6e-57 193.3 6.1 4.6e-37 128.1 0.6 2.3 2 1 0 2 2 2 2 Signal peptide peptidase Presenilin PF01080.17 EJP64410.1 - 8.3 5.1 9.5 0.072 11.8 0.3 2.2 3 0 0 3 3 3 0 Presenilin ACPS PF01648.20 EJP64411.1 - 4.5e-09 36.4 0.0 8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DLH PF01738.18 EJP64412.1 - 2.4e-19 69.8 0.0 2.8e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_8 PF06259.12 EJP64412.1 - 0.076 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF3482 PF11981.8 EJP64414.1 - 0.046 13.1 0.0 0.049 13.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) PI-PLC-X PF00388.19 EJP64416.1 - 1.1e-48 164.5 0.3 9.1e-36 122.6 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EJP64416.1 - 1.3e-37 128.7 0.1 3.3e-37 127.3 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain KCNQ2_u3 PF16642.5 EJP64416.1 - 0.036 15.1 0.4 0.036 15.1 0.4 2.5 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 EF-hand_like PF09279.11 EJP64416.1 - 0.05 14.1 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF594 PF04578.13 EJP64416.1 - 0.16 11.5 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF594 CDC13_N PF16853.5 EJP64417.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus Inhibitor_I69 PF13734.6 EJP64417.1 - 0.14 12.6 1.2 0.99 9.9 0.0 2.6 2 0 0 2 2 2 0 Spi protease inhibitor Glyco_hydro_35 PF01301.19 EJP64418.1 - 1e-90 304.6 0.0 1.3e-90 304.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EJP64418.1 - 3.4e-60 203.0 1.4 5.3e-60 202.3 1.4 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EJP64418.1 - 3.8e-49 166.0 1.6 2.4e-24 86.1 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EJP64418.1 - 1.2e-23 82.5 0.2 2.4e-23 81.5 0.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Amidohydro_1 PF01979.20 EJP64419.1 - 3.7e-21 75.8 0.1 3.7e-20 72.5 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EJP64419.1 - 8.6e-07 28.8 0.7 2.7e-06 27.1 0.6 1.7 1 1 0 1 1 1 1 Amidohydrolase family PdxJ PF03740.13 EJP64419.1 - 0.018 14.1 0.1 0.035 13.2 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Urocanase_C PF17392.2 EJP64419.1 - 0.024 14.1 0.1 0.046 13.1 0.1 1.5 1 0 0 1 1 1 0 Urocanase C-terminal domain Trypsin PF00089.26 EJP64420.1 - 3.9e-37 128.2 3.5 1.5e-23 83.8 0.0 2.1 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.6 EJP64420.1 - 1.7e-07 32.3 0.3 4.9e-06 27.5 0.5 2.6 2 1 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.11 EJP64420.1 - 0.13 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) MFS_1 PF07690.16 EJP64422.1 - 6.5e-43 147.0 38.2 1.9e-30 106.0 6.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EJP64422.1 - 0.00078 17.9 8.7 0.00078 17.9 8.7 3.1 3 1 0 3 3 3 2 Transmembrane secretion effector MFS_5 PF05631.14 EJP64422.1 - 0.0016 17.4 1.5 0.0019 17.2 0.4 1.8 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 EJP64422.1 - 0.0035 16.3 6.7 0.0035 16.3 6.7 2.6 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 EJP64422.1 - 0.0043 15.4 8.8 0.0054 15.1 0.8 2.8 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 EJP64422.1 - 0.17 10.1 6.7 0.025 12.8 1.7 1.9 2 0 0 2 2 2 0 BT1 family DUF2439 PF10382.9 EJP64423.1 - 2.7e-26 91.7 0.1 5.5e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Zn_clus PF00172.18 EJP64424.1 - 0.19 11.9 8.2 0.32 11.2 8.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.23 EJP64425.1 - 5.3e-19 68.0 0.0 4.4e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EJP64425.1 - 2.7e-16 59.6 0.0 5e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 EJP64425.1 - 0.0012 18.9 2.1 0.012 15.7 0.0 2.8 3 0 0 3 3 3 1 Bd3614-like deaminase OPT PF03169.15 EJP64426.1 - 7.7e-154 513.7 45.4 9e-154 513.5 45.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S10 PF00450.22 EJP64427.1 - 4.6e-96 322.8 1.0 6e-96 322.4 1.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Bep_C_terminal PF17841.1 EJP64428.1 - 0.032 14.4 0.2 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) DUF971 PF06155.12 EJP64428.1 - 0.1 13.2 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF971) E1-E2_ATPase PF00122.20 EJP64429.1 - 6.1e-51 172.5 4.6 6.1e-51 172.5 4.6 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EJP64429.1 - 1.8e-22 80.7 1.2 4e-22 79.5 1.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EJP64429.1 - 2.2e-10 40.8 0.1 1.8e-08 34.7 0.1 2.7 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EJP64429.1 - 0.058 13.1 1.4 4 7.1 0.2 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 EJP64430.1 - 8.1e-10 38.7 9.7 1.5e-09 37.8 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP64430.1 - 0.0086 15.1 0.0 0.018 14.1 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Croc_4 PF17691.1 EJP64430.1 - 0.02 14.9 2.4 0.059 13.4 2.4 1.8 1 0 0 1 1 1 0 Contingent replication of cDNA 4 Totivirus_coat PF05518.11 EJP64430.1 - 0.13 10.3 3.4 0.23 9.5 3.4 1.3 1 0 0 1 1 1 0 Totivirus coat protein Glyco_hydro_35 PF01301.19 EJP64431.1 - 2.4e-91 306.7 0.0 3.3e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EJP64431.1 - 4.8e-59 199.2 1.8 7.8e-59 198.5 1.8 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EJP64431.1 - 1e-46 158.2 3.6 8.8e-25 87.5 0.1 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EJP64431.1 - 3.4e-25 87.4 0.0 7.5e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Sugar_tr PF00083.24 EJP64432.1 - 1.1e-94 317.8 22.5 1.3e-94 317.6 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP64432.1 - 5.5e-17 61.7 44.7 1.7e-16 60.1 26.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EJP64432.1 - 0.0014 17.3 2.3 0.0014 17.3 2.3 3.0 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 EJP64432.1 - 0.51 9.1 14.7 0.082 11.8 5.9 2.4 2 0 0 2 2 2 0 MFS_1 like family DUF2207 PF09972.9 EJP64432.1 - 7.7 5.2 5.3 17 4.0 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Alpha-amylase PF00128.24 EJP64433.1 - 3e-109 365.7 0.0 4.1e-109 365.2 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EJP64433.1 - 1.5e-05 25.0 0.0 4.8e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain Glyoxalase_6 PF18029.1 EJP64433.1 - 0.0045 17.8 0.1 0.022 15.5 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase-like domain PMI_typeI PF01238.21 EJP64433.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Phosphomannose isomerase type I hDGE_amylase PF14701.6 EJP64433.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EJP64434.1 - 0.033 13.1 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Zn_clus PF00172.18 EJP64435.1 - 4.8e-05 23.4 2.9 0.00011 22.2 2.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PA PF02225.22 EJP64436.1 - 0.0073 16.3 0.1 0.018 15.1 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 EJP64436.1 - 0.028 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 2OG-FeII_Oxy PF03171.20 EJP64437.1 - 0.00014 22.3 0.0 0.00024 21.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EJP64437.1 - 0.0084 16.9 0.0 0.015 16.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Xan_ur_permease PF00860.20 EJP64438.1 - 4.7e-21 74.9 35.3 1.9e-10 40.0 10.7 3.2 3 1 0 3 3 3 3 Permease family Sulfate_transp PF00916.20 EJP64438.1 - 0.00013 20.9 2.8 0.00013 20.9 2.8 2.6 2 1 0 2 2 2 1 Sulfate permease family NADH-u_ox-rdase PF10785.9 EJP64440.1 - 1.9e-28 99.0 0.1 4.1e-28 97.9 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EJP64440.1 - 4.3e-25 87.5 0.1 5.8e-25 87.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 EJP64441.1 - 1.9e-30 104.7 0.4 3e-30 104.0 0.4 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 4HBT PF03061.22 EJP64442.1 - 4.2e-06 27.0 0.0 6.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Glyco_hydro_79C PF16862.5 EJP64443.1 - 5.5e-24 85.0 0.0 1.1e-23 84.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 EJP64443.1 - 0.057 12.3 0.1 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 79, N-terminal domain DUF3759 PF12585.8 EJP64445.1 - 1.9e-41 140.0 6.4 2.5e-41 139.6 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) bZIP_2 PF07716.15 EJP64446.1 - 3.4e-08 33.5 11.6 7.2e-08 32.4 11.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EJP64446.1 - 3.5e-05 23.8 12.7 6.6e-05 22.9 12.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EJP64446.1 - 0.024 15.1 9.4 0.051 14.1 9.4 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor SprA-related PF12118.8 EJP64446.1 - 0.059 12.5 3.4 0.11 11.6 3.4 1.4 1 0 0 1 1 1 0 SprA-related family LSPR PF06049.12 EJP64446.1 - 2.1 8.5 6.1 29 5.1 0.5 4.1 3 0 0 3 3 3 0 Coagulation Factor V LSPD Repeat Toxin_6 PF05453.12 EJP64448.1 - 1.4 9.4 0.1 1.4 9.4 0.1 3.0 3 0 0 3 3 3 0 BmTXKS1/BmP02 toxin family Zn_clus PF00172.18 EJP64451.1 - 7.1e-06 26.1 13.8 7.1e-06 26.1 13.8 2.1 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 EJP64451.1 - 0.028 14.5 7.1 0.27 11.3 2.5 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Aim19 PF10315.9 EJP64452.1 - 7.5e-05 23.0 3.7 0.00023 21.4 1.0 2.1 1 1 1 2 2 2 2 Altered inheritance of mitochondria protein 19 Cornifin PF02389.15 EJP64453.1 - 0.00027 21.1 1.8 0.00048 20.3 1.8 1.4 1 1 0 1 1 1 1 Cornifin (SPRR) family DHDPS PF00701.22 EJP64455.1 - 3e-40 137.7 0.0 3.8e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CHASE9 PF17153.4 EJP64455.1 - 0.23 11.6 0.0 0.37 11.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular Aldolase_II PF00596.21 EJP64456.1 - 1.6e-35 122.7 0.0 2.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.18 EJP64457.1 - 8.4e-28 97.1 0.4 1.3e-27 96.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain VESA1_N PF12785.7 EJP64459.1 - 1.1 8.2 11.1 1.2 8.0 11.1 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Glyco_transf_17 PF04724.13 EJP64460.1 - 1.9e-50 171.9 0.0 3e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 Patatin PF01734.22 EJP64460.1 - 0.16 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase Rol_Rep_N PF18106.1 EJP64461.1 - 0.081 13.3 0.3 4 7.8 0.0 2.3 2 0 0 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain SDA1 PF05285.12 EJP64461.1 - 2.9 7.2 16.2 3.8 6.8 16.2 1.2 1 0 0 1 1 1 0 SDA1 HAD_2 PF13419.6 EJP64462.1 - 1.6e-19 70.7 0.0 2.1e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP64462.1 - 1.4e-09 38.6 0.0 2.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP64462.1 - 0.00011 22.7 0.0 0.00016 22.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP64462.1 - 0.0052 16.8 0.0 0.0096 16.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like 5_nucleotid PF05761.14 EJP64462.1 - 0.04 12.8 0.1 11 4.8 0.0 2.9 2 1 0 3 3 3 0 5' nucleotidase family Zein-binding PF04576.15 EJP64462.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Zein-binding NmrA PF05368.13 EJP64463.1 - 7.8e-81 271.0 0.0 9.7e-81 270.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP64463.1 - 1.7e-08 34.6 0.0 7.4e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding DUF3798 PF12683.7 EJP64463.1 - 0.036 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) PTR2 PF00854.21 EJP64464.1 - 4.4e-73 246.4 5.6 5.5e-73 246.1 5.6 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EJP64464.1 - 7.8e-05 21.7 25.8 0.00035 19.6 21.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM_GPCR_Srv PF10323.9 EJP64464.1 - 0.011 15.1 1.0 0.039 13.3 1.0 1.9 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv ERG2_Sigma1R PF04622.12 EJP64465.1 - 4.3e-96 320.2 0.1 5e-96 320.0 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 EJP64465.1 - 0.036 14.0 0.2 0.68 9.9 0.1 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein NPCC PF08058.11 EJP64467.1 - 3.4e-30 104.7 0.0 4.6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component DUF2417 PF10329.9 EJP64467.1 - 0.061 12.7 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Aa_trans PF01490.18 EJP64468.1 - 1.8e-87 293.7 29.6 2.2e-87 293.4 29.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 EJP64469.1 - 6.4e-54 183.3 36.4 8e-54 183.0 36.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EJP64469.1 - 3.2e-23 82.5 1.7 2e-09 37.0 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 EJP64469.1 - 2.6e-16 59.5 40.9 3.9e-16 58.9 40.9 1.2 1 0 0 1 1 1 1 Amino acid permease cobW PF02492.19 EJP64470.1 - 3.3e-39 134.3 0.0 4.8e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EJP64470.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EJP64470.1 - 0.024 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EJP64470.1 - 0.03 14.2 0.2 0.073 13.0 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 EJP64470.1 - 0.043 13.6 0.2 0.4 10.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF463 PF04317.12 EJP64470.1 - 0.049 12.6 0.0 0.09 11.7 0.0 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_22 PF13401.6 EJP64470.1 - 0.05 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EJP64470.1 - 0.058 13.3 0.0 9.6 6.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 EJP64470.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 EJP64470.1 - 0.096 11.6 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 EJP64470.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PUL PF08324.11 EJP64472.1 - 1.1e-57 195.3 0.1 1.6e-57 194.9 0.1 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EJP64472.1 - 3.2e-33 114.7 0.0 5.1e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 EJP64472.1 - 3.5e-17 62.3 0.1 7.1e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EJP64472.1 - 3.9e-08 33.4 0.1 6.9e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EJP64472.1 - 2.7e-06 27.0 0.3 4e-06 26.4 0.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EJP64472.1 - 1.7e-05 25.2 0.1 6.6e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EJP64472.1 - 0.011 15.8 0.0 0.075 13.1 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.24 EJP64472.1 - 0.049 13.9 0.2 0.27 11.5 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin T4_deiodinase PF00837.17 EJP64472.1 - 0.085 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin_8 PF13905.6 EJP64472.1 - 0.11 12.9 0.0 0.39 11.1 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like SSP160 PF06933.11 EJP64473.1 - 0.12 10.5 20.8 0.2 9.8 20.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TRP PF06011.12 EJP64473.1 - 0.86 8.3 2.6 0.49 9.1 0.1 1.7 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel MRI PF15325.6 EJP64473.1 - 2.7 9.1 10.2 5.5 8.1 0.0 2.7 2 0 0 2 2 2 0 Modulator of retrovirus infection ABC_membrane PF00664.23 EJP64474.1 - 1.4e-54 185.7 40.2 7.5e-38 130.7 18.2 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EJP64474.1 - 5.7e-47 159.7 0.0 1.3e-26 93.7 0.0 3.1 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EJP64474.1 - 8.7e-07 29.5 0.2 0.025 14.9 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EJP64474.1 - 5.9e-05 23.1 1.0 0.075 13.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP64474.1 - 0.00029 20.8 0.6 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 EJP64474.1 - 0.00047 19.5 0.0 0.055 12.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 EJP64474.1 - 0.003 16.6 1.0 0.96 8.4 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EJP64474.1 - 0.0084 15.8 5.4 4.1 7.1 0.1 3.7 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.6 EJP64474.1 - 0.018 14.7 1.2 5.2 6.9 0.2 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP64474.1 - 0.019 15.2 3.8 5.1 7.4 0.1 3.4 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 EJP64474.1 - 0.04 13.3 5.5 9.1 5.6 0.6 3.6 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP64474.1 - 0.049 13.4 0.4 9.3 6.0 0.0 3.3 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EJP64474.1 - 0.05 13.3 0.0 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 EJP64474.1 - 0.054 13.1 0.1 5.5 6.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 EJP64474.1 - 0.073 12.6 0.7 2.6 7.5 0.2 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EJP64474.1 - 0.099 13.0 0.1 12 6.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 EJP64474.1 - 0.12 12.6 0.2 17 5.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EJP64474.1 - 0.14 12.1 0.2 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 EJP64474.1 - 0.33 11.0 10.1 0.96 9.5 0.2 3.5 3 0 0 3 3 3 0 Dynamin family CDC45 PF02724.14 EJP64474.1 - 0.83 7.9 15.2 0.019 13.3 2.0 3.0 3 0 0 3 3 3 0 CDC45-like protein DDHD PF02862.17 EJP64474.1 - 1 9.5 3.9 8 6.5 0.0 3.2 3 0 0 3 3 3 0 DDHD domain NB-ARC PF00931.22 EJP64474.1 - 2.1 7.5 4.7 20 4.3 0.6 3.1 3 0 0 3 3 3 0 NB-ARC domain DUF87 PF01935.17 EJP64474.1 - 3.1 7.8 12.2 0.22 11.6 0.4 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain GAGA_bind PF06217.12 EJP64474.1 - 5.5 7.2 9.0 2.1 8.6 1.2 2.9 3 0 0 3 3 3 0 GAGA binding protein-like family EXOSC1 PF10447.9 EJP64475.1 - 5.7e-19 68.7 5.8 5.2e-14 52.8 0.4 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EJP64475.1 - 8.7e-10 38.2 0.5 1.8e-09 37.3 0.2 1.6 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region PCB_OB PF17092.5 EJP64475.1 - 0.016 15.9 2.1 0.022 15.5 1.5 1.6 1 1 1 2 2 2 0 Penicillin-binding protein OB-like domain Sec2p PF06428.11 EJP64476.1 - 1.2e-10 41.2 7.5 1.2e-10 41.2 7.5 1.6 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p HAUS-augmin3 PF14932.6 EJP64476.1 - 0.0087 15.7 6.4 0.23 11.0 4.8 2.5 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 Jnk-SapK_ap_N PF09744.9 EJP64476.1 - 0.036 14.3 9.5 0.62 10.3 9.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CHDCT2 PF08074.11 EJP64476.1 - 0.053 13.7 2.9 0.084 13.0 2.9 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF4140 PF13600.6 EJP64476.1 - 0.055 13.9 6.2 1.1 9.7 0.0 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 EJP64476.1 - 0.12 11.2 7.6 3.9 6.3 7.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EJP64476.1 - 0.31 10.6 5.1 0.41 10.2 3.4 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit SlyX PF04102.12 EJP64476.1 - 0.4 11.3 9.6 1.3 9.7 1.2 3.8 3 1 2 5 5 5 0 SlyX DivIC PF04977.15 EJP64476.1 - 0.65 9.8 6.2 0.93 9.3 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator DNA_ligase_ZBD PF03119.16 EJP64476.1 - 0.73 9.9 3.0 1.8 8.7 3.0 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain BST2 PF16716.5 EJP64476.1 - 1.1 9.9 6.6 27 5.4 0.0 2.7 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 Atg14 PF10186.9 EJP64476.1 - 1.2 8.1 7.0 31 3.5 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PP1_bind PF15276.6 EJP64476.1 - 2.5 8.5 6.3 0.7 10.2 1.2 2.4 1 1 1 2 2 2 0 Protein phosphatase 1 binding DUF4407 PF14362.6 EJP64476.1 - 3.3 7.0 7.7 62 2.8 7.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 EJP64476.1 - 7.9 6.5 12.8 4.9 7.2 9.4 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Aconitase PF00330.20 EJP64477.1 - 1.8e-99 333.8 0.0 1.6e-98 330.7 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EJP64477.1 - 8e-26 90.9 0.0 1.6e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain p450 PF00067.22 EJP64478.1 - 9.1e-45 153.2 0.0 1.2e-44 152.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HHH_8 PF14716.6 EJP64478.1 - 0.02 15.3 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain PUL PF08324.11 EJP64478.1 - 0.095 11.9 0.1 0.91 8.7 0.0 2.0 2 0 0 2 2 2 0 PUL domain p450 PF00067.22 EJP64479.1 - 1.1e-72 245.3 0.0 1.3e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vac14_Fab1_bd PF12755.7 EJP64479.1 - 0.011 16.3 0.0 0.034 14.7 0.0 1.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Cucumopine_C PF18631.1 EJP64480.1 - 9.8e-49 164.9 0.1 1.4e-48 164.4 0.1 1.2 1 0 0 1 1 1 1 Cucumopine synthase C-terminal helical bundle domain DUF3830 PF12903.7 EJP64480.1 - 0.0046 16.7 0.0 0.045 13.5 0.0 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF3830) AMP-binding PF00501.28 EJP64481.1 - 4.8e-42 144.0 0.0 6.4e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP64481.1 - 7.9e-06 26.8 0.0 8.5e-05 23.5 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain UPF0220 PF05255.11 EJP64482.1 - 1.4e-65 219.9 2.4 1.6e-65 219.7 2.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Glyco_hydro_3_C PF01915.22 EJP64483.1 - 0.25 11.3 1.2 0.35 10.8 1.2 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF410 PF04190.13 EJP64484.1 - 3.6e-93 312.0 0.0 4.4e-93 311.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Suc_Fer-like PF06999.12 EJP64485.1 - 8.8e-61 205.2 0.0 1.1e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Myb_DNA-bind_2 PF08914.11 EJP64485.1 - 0.28 11.4 0.6 0.67 10.2 0.2 1.8 2 0 0 2 2 2 0 Rap1 Myb domain FAD_binding_6 PF00970.24 EJP64486.1 - 9.4e-07 29.1 0.0 8.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EJP64486.1 - 4.4e-06 27.3 0.0 2.6e-05 24.8 0.0 2.2 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EJP64486.1 - 0.0057 16.8 0.0 0.0098 16.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Abhydrolase_6 PF12697.7 EJP64488.1 - 7.4e-23 82.3 3.3 8.4e-23 82.1 3.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 EJP64488.1 - 0.0098 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 EJP64488.1 - 0.071 12.7 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lactamase_B_2 PF12706.7 EJP64489.1 - 3.8e-14 52.7 1.0 7e-14 51.8 0.9 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EJP64489.1 - 3.5e-12 46.5 0.3 9.5e-12 45.1 0.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EJP64489.1 - 0.0078 16.2 5.1 0.016 15.2 4.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PhoLip_ATPase_C PF16212.5 EJP64490.1 - 1.4e-50 172.4 6.9 1.4e-50 172.4 6.9 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EJP64490.1 - 3e-16 58.8 0.6 1.2e-15 57.0 0.7 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EJP64490.1 - 6.7e-12 46.1 1.9 5.2e-06 26.9 0.2 3.9 3 2 1 4 4 4 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EJP64490.1 - 1.4e-08 34.5 1.8 8.3e-07 28.7 1.8 2.7 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EJP64490.1 - 1.6e-06 28.1 0.0 5.2e-05 23.3 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EJP64490.1 - 0.0025 17.6 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ferritin_2 PF13668.6 EJP64491.1 - 1.5e-06 28.5 1.8 2.3e-06 27.9 1.8 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4126 PF13548.6 EJP64491.1 - 0.064 13.0 0.6 0.11 12.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) Sec16_C PF12931.7 EJP64492.1 - 3.3e-110 368.5 0.0 4.9e-110 367.9 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EJP64492.1 - 2.6e-34 118.4 0.0 1.1e-33 116.4 0.0 2.2 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 EJP64492.1 - 8e-08 32.7 27.1 8e-08 32.7 27.1 6.0 3 1 3 6 6 6 2 Vesicle coat trafficking protein Sec16 N-terminus Hus1 PF04005.12 EJP64493.1 - 1.5e-89 300.0 0.0 1.7e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Ribosomal_60s PF00428.19 EJP64493.1 - 1.5 9.4 15.4 1.2 9.8 5.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Adeno_PIX PF03955.14 EJP64493.1 - 5.2 7.3 14.0 0.14 12.3 5.0 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF4501 PF14946.6 EJP64494.1 - 0.055 13.5 0.2 0.075 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) DUF4609 PF15382.6 EJP64494.1 - 0.056 13.3 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) NICE-3 PF07406.11 EJP64496.1 - 0.057 13.4 0.1 0.076 13.0 0.1 1.1 1 0 0 1 1 1 0 NICE-3 protein FH2 PF02181.23 EJP64497.1 - 8.3e-84 281.8 2.3 1.6e-83 280.9 2.3 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EJP64497.1 - 1.2e-57 194.6 0.0 1.2e-57 194.6 0.0 2.4 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EJP64497.1 - 1.6e-50 171.5 2.0 4.6e-50 170.0 2.0 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain INCA1 PF15142.6 EJP64497.1 - 0.013 15.5 0.3 0.013 15.5 0.3 2.6 2 0 0 2 2 2 0 INCA1 SNRNP27 PF08648.12 EJP64498.1 - 5.1e-28 96.9 2.9 5.1e-28 96.9 2.9 1.9 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins TPPII_N PF12583.8 EJP64498.1 - 0.49 11.0 2.8 0.75 10.4 1.8 1.6 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Helo_like_N PF17111.5 EJP64499.1 - 0.091 12.1 0.0 1.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Mannosyl_trans3 PF11051.8 EJP64500.1 - 2.1e-57 194.6 0.0 1.2e-56 192.1 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_hydro_63 PF03200.16 EJP64501.1 - 1.6e-172 574.7 0.8 2.3e-171 570.9 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EJP64501.1 - 3.9e-81 272.5 1.7 1.8e-79 267.0 0.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EJP64501.1 - 5.5e-06 25.5 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Trehalase Beta-lactamase PF00144.24 EJP64502.1 - 2.9e-40 138.5 1.1 3.9e-40 138.1 1.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EJP64502.1 - 0.032 14.7 0.0 0.077 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Thioredoxin PF00085.20 EJP64503.1 - 3.9e-25 87.8 0.1 4.4e-25 87.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EJP64503.1 - 1.7e-09 38.1 0.2 4.9e-09 36.6 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EJP64503.1 - 4.5e-07 30.1 0.0 1.7e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EJP64503.1 - 8e-07 28.7 0.1 8.8e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EJP64503.1 - 4.9e-06 26.3 0.2 7.9e-06 25.6 0.2 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EJP64503.1 - 1e-05 25.5 0.1 2.1e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EJP64503.1 - 0.00016 21.8 0.1 0.00026 21.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EJP64503.1 - 0.00042 20.1 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EJP64503.1 - 0.00056 19.7 0.7 0.16 11.7 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain TraF PF13728.6 EJP64503.1 - 0.0055 16.6 0.1 0.013 15.3 0.1 1.5 1 1 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 EJP64503.1 - 0.017 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 EJP64503.1 - 0.02 14.9 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Glutaredoxin PF00462.24 EJP64503.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin MnmE_helical PF12631.7 EJP64504.1 - 7.7e-33 114.4 0.6 1e-32 114.0 0.6 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EJP64504.1 - 5.7e-23 81.4 0.0 1.3e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EJP64504.1 - 4.5e-19 68.6 0.0 9.6e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJP64504.1 - 3.1e-06 26.8 0.0 4.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EJP64504.1 - 2.2e-05 24.6 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 EJP64504.1 - 0.0024 18.4 0.1 0.0058 17.1 0.1 1.7 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EJP64504.1 - 0.0096 15.8 0.1 0.22 11.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Glyco_hydro_3_C PF01915.22 EJP64504.1 - 0.015 15.2 0.2 0.05 13.5 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AAA_24 PF13479.6 EJP64504.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.26 EJP64505.1 - 3.3e-50 170.2 0.1 4.1e-50 169.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJP64505.1 - 4.6e-11 42.2 0.2 7.5e-11 41.5 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.14 EJP64506.1 - 4.3e-30 104.5 0.0 6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EJP64506.1 - 2.6e-05 23.9 0.9 4.9e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 SLOG cluster4 family CLPTM1 PF05602.12 EJP64507.1 - 5.2e-147 490.3 0.0 8e-147 489.7 0.0 1.3 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Virul_fac_BrkB PF03631.15 EJP64507.1 - 0.62 9.6 6.9 0.41 10.2 1.1 2.4 2 0 0 2 2 2 0 Virulence factor BrkB DUF4293 PF14126.6 EJP64507.1 - 0.86 9.8 4.6 0.91 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Elong_Iki1 PF10483.9 EJP64509.1 - 9.9e-72 241.9 0.0 1.5e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.6 EJP64509.1 - 3.2e-24 84.8 0.3 9.1e-24 83.3 0.1 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EJP64509.1 - 1.2e-15 57.0 0.3 2.7e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin DUF4311 PF14188.6 EJP64509.1 - 0.067 13.0 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) DUF1664 PF07889.12 EJP64509.1 - 0.084 12.9 0.5 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ASXH PF13919.6 EJP64510.1 - 2.4e-38 131.3 0.6 3.6e-38 130.7 0.6 1.2 1 0 0 1 1 1 1 Asx homology domain MFS_1 PF07690.16 EJP64511.1 - 1.2e-18 67.1 54.1 1.2e-18 67.1 54.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 EJP64512.1 - 1e-19 71.6 0.4 2.2e-19 70.5 0.4 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EJP64512.1 - 8.6e-08 32.4 0.0 2.2e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase bZIP_Maf PF03131.17 EJP64514.1 - 0.011 16.2 0.5 0.011 16.2 0.5 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Fic PF02661.18 EJP64515.1 - 6.8e-14 52.5 0.0 1.2e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Ytp1 PF10355.9 EJP64516.1 - 3e-67 226.8 23.4 3e-67 226.8 23.4 2.2 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EJP64516.1 - 8e-31 105.9 0.8 8e-31 105.9 0.8 3.0 2 1 0 3 3 3 1 Domain of unknown function (DUF2427) Med11 PF10280.9 EJP64517.1 - 8.9e-46 155.8 0.1 1e-45 155.5 0.1 1.0 1 0 0 1 1 1 1 Mediator complex protein TFIID_NTD2 PF04494.15 EJP64518.1 - 2.7e-39 134.4 0.0 4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 EJP64518.1 - 1.4e-36 123.9 18.1 2.4e-07 31.3 0.3 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP64518.1 - 1e-11 45.0 0.1 0.26 11.6 0.0 5.4 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EJP64518.1 - 4.3e-08 32.8 0.1 4.4e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 LisH Ge1_WD40 PF16529.5 EJP64518.1 - 0.00016 20.7 0.4 1.2 8.0 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EJP64518.1 - 0.016 14.0 0.1 19 3.9 0.0 3.7 2 2 2 4 4 4 0 Nup133 N terminal like Nup160 PF11715.8 EJP64518.1 - 0.034 12.8 0.0 3.3 6.2 0.0 3.1 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 EJP64518.1 - 0.13 11.6 0.5 9.6 5.4 0.1 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 EJP64518.1 - 0.17 11.1 0.0 8.4 5.5 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Vps5 PF09325.10 EJP64519.1 - 1.5e-88 296.4 7.7 2.5e-88 295.6 7.7 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EJP64519.1 - 1.7e-23 82.8 0.1 3.8e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 EJP64519.1 - 0.0026 17.5 8.3 0.019 14.7 4.9 2.5 1 1 1 2 2 2 1 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 EJP64519.1 - 0.0087 15.5 2.0 0.053 13.0 2.0 2.0 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_2 PF10455.9 EJP64519.1 - 0.25 10.4 8.2 0.68 9.0 8.2 1.7 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EJP64519.1 - 0.81 9.3 11.5 1.4 8.5 11.5 1.4 1 1 0 1 1 1 0 BAR domain Flavin_Reduct PF01613.18 EJP64521.1 - 5.6e-31 107.7 0.1 7.3e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain HSP90 PF00183.18 EJP64522.1 - 2.1e-222 739.6 27.4 2.6e-222 739.3 27.4 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EJP64522.1 - 2.8e-14 53.6 0.1 5.3e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EJP64522.1 - 3.5e-10 39.8 0.1 3.5e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 EJP64522.1 - 0.053 13.5 0.3 0.2 11.7 0.3 2.0 1 0 0 1 1 1 0 Tumour suppressor protein MBOAT PF03062.19 EJP64523.1 - 2.3e-38 132.5 18.2 1.8e-37 129.5 11.8 2.2 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 EJP64523.1 - 0.027 15.1 5.9 1.8 9.2 3.4 2.8 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC53 PF10152.9 EJP64523.1 - 0.2 12.1 0.9 1.1 9.7 0.5 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF4805 PF16063.5 EJP64523.1 - 1.9 7.8 6.3 0.26 10.6 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) PBP_N PF17093.5 EJP64523.1 - 8 6.7 10.0 2 8.7 2.9 2.6 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus DnaJ PF00226.31 EJP64524.1 - 4.5e-20 71.5 1.3 4.5e-20 71.5 1.3 2.5 3 0 0 3 3 3 1 DnaJ domain Methyltransf_25 PF13649.6 EJP64525.1 - 9.3e-10 39.1 0.0 2.8e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP64525.1 - 6.6e-09 36.3 0.0 3.3e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP64525.1 - 1.1e-07 32.5 0.0 3.5e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP64525.1 - 5.3e-06 26.3 0.0 7.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP64525.1 - 0.00023 21.0 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EJP64525.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Metallophos PF00149.28 EJP64526.1 - 1.8e-11 44.9 0.0 8.8e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP64526.1 - 4.3e-05 23.8 0.1 0.0061 16.8 0.0 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Flavi_NS5 PF00972.20 EJP64526.1 - 0.13 10.4 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase PBP PF01161.20 EJP64528.1 - 0.00069 19.9 0.1 0.00076 19.8 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CUE PF02845.16 EJP64529.1 - 2.6e-07 30.2 0.0 4.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 EJP64529.1 - 0.012 15.7 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 Ofd1_CTDD PF10637.9 EJP64531.1 - 3.6e-93 311.6 0.1 1.8e-86 289.6 0.4 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EJP64531.1 - 2.4e-27 95.5 0.0 4.7e-26 91.3 0.0 2.6 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EJP64531.1 - 5.5e-13 49.6 0.0 1.7e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tannase PF07519.11 EJP64533.1 - 2.2e-91 307.1 0.1 2.6e-91 306.9 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EJP64533.1 - 2.1e-08 33.9 0.1 0.00058 19.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EJP64533.1 - 3.6e-05 23.2 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP64533.1 - 8.3e-05 22.3 0.0 0.00025 20.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3638 PF12340.8 EJP64534.1 - 1.1e-89 299.6 0.5 2.4e-89 298.5 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EJP64534.1 - 9.4e-14 50.5 0.1 2.3e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DEAD PF00270.29 EJP64534.1 - 0.045 13.5 0.2 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Pyr_redox_3 PF13738.6 EJP64535.1 - 9.7e-15 54.6 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EJP64535.1 - 1.6e-13 50.0 0.0 7.5e-13 47.7 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EJP64535.1 - 2.4e-09 37.3 0.0 8e-08 32.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EJP64535.1 - 3.2e-08 33.1 0.0 7.5e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EJP64535.1 - 7.4e-08 31.9 0.0 0.00091 18.5 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EJP64535.1 - 1.1e-07 31.4 0.1 2.2e-06 27.1 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP64535.1 - 2.8e-07 30.5 0.0 1.2e-05 25.1 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Mqo PF06039.15 EJP64535.1 - 6.9e-07 28.2 0.0 0.017 13.7 0.0 2.6 2 1 1 3 3 3 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 EJP64535.1 - 2.6e-05 24.7 0.1 0.41 11.2 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EJP64535.1 - 0.00012 21.2 0.1 0.0061 15.7 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EJP64535.1 - 0.00043 19.5 0.1 0.035 13.2 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 EJP64535.1 - 0.00081 19.4 0.2 0.09 12.8 0.0 3.7 4 1 1 5 5 5 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EJP64535.1 - 0.048 14.1 0.0 0.25 11.8 0.0 2.1 3 0 0 3 3 3 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EJP64535.1 - 0.057 13.5 0.0 0.68 10.0 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EJP64535.1 - 0.11 12.2 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 EJP64535.1 - 0.11 11.8 0.0 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Aminotran_5 PF00266.19 EJP64536.1 - 2.7e-57 194.4 0.0 5.5e-57 193.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EJP64536.1 - 4.5e-06 25.4 0.0 6.5e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CFEM PF05730.11 EJP64537.1 - 7.6e-13 48.4 11.2 1.6e-12 47.3 11.2 1.5 1 0 0 1 1 1 1 CFEM domain RAP1 PF07218.11 EJP64537.1 - 0.34 9.1 8.2 0.38 9.0 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_capsid PF06112.11 EJP64537.1 - 6.7 6.8 15.7 12 5.9 15.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ysc84 PF04366.12 EJP64538.1 - 1.1e-46 157.8 0.2 1.7e-46 157.2 0.2 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator AdoMet_dc PF02675.15 EJP64538.1 - 0.044 14.0 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase TMEM171 PF15471.6 EJP64538.1 - 4.5 6.2 5.7 9.3 5.1 5.7 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 GMC_oxred_N PF00732.19 EJP64539.1 - 7.1e-59 199.6 0.0 1.1e-58 199.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP64539.1 - 2.8e-33 115.5 0.0 5.7e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase SEP PF08059.13 EJP64540.1 - 3.5e-24 85.1 0.2 8.4e-24 84.0 0.0 1.7 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 EJP64540.1 - 1.2e-14 53.8 0.1 1.9e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EJP64540.1 - 1e-09 38.5 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 EJP64540.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 TAP C-terminal domain PASTA PF03793.19 EJP64540.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 PASTA domain Gtr1_RagA PF04670.12 EJP64541.1 - 2.3e-93 311.9 0.0 2.9e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EJP64541.1 - 7.8e-08 32.6 0.0 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJP64541.1 - 1.5e-07 31.2 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EJP64541.1 - 1.5e-07 31.5 0.0 4.1e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 EJP64541.1 - 2.6e-07 30.3 0.0 3.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EJP64541.1 - 0.00092 18.5 2.7 0.31 10.2 0.3 2.7 2 1 1 3 3 3 2 G-protein alpha subunit ABC_tran PF00005.27 EJP64541.1 - 0.0034 17.9 0.1 0.0071 16.9 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EJP64541.1 - 0.0067 16.1 0.3 0.049 13.4 0.2 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP64541.1 - 0.0091 15.9 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 EJP64541.1 - 0.019 14.1 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EJP64541.1 - 0.11 12.0 0.1 0.44 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EJP64541.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Sugar_tr PF00083.24 EJP64542.1 - 2.4e-28 99.2 24.7 2.4e-22 79.4 8.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EJP64542.1 - 6.9e-26 91.0 29.1 6.9e-26 91.0 29.1 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily Glyco_transf_21 PF13506.6 EJP64543.1 - 1.3e-13 50.8 0.0 4.5e-07 29.5 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EJP64543.1 - 7.1e-10 39.2 0.0 1.1e-09 38.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EJP64543.1 - 3e-06 27.2 0.0 2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 tRNA_int_endo PF01974.17 EJP64544.1 - 7e-18 64.5 0.0 1.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EJP64544.1 - 0.0005 19.7 0.0 0.73 9.5 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain RecX PF02631.16 EJP64544.1 - 0.041 14.3 2.4 0.079 13.4 2.4 1.4 1 0 0 1 1 1 0 RecX family TauD PF02668.16 EJP64545.1 - 7e-38 130.9 0.0 1.3e-37 130.1 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EJP64545.1 - 1.8e-06 28.5 0.1 4.9e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF971) Pro_Al_protease PF02983.14 EJP64545.1 - 0.13 12.4 2.0 0.42 10.7 0.3 2.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain SPATA3 PF15662.5 EJP64545.1 - 0.18 12.4 1.0 0.28 11.8 1.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family SGS PF05002.15 EJP64546.1 - 3.6e-28 97.5 1.4 3.6e-28 97.5 1.4 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.16 EJP64546.1 - 2e-10 41.6 0.1 3.5e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EJP64546.1 - 7.8e-10 38.1 3.6 0.0019 18.2 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EJP64546.1 - 8.8e-06 25.3 3.5 0.0011 18.7 0.6 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP64546.1 - 1.3e-05 25.6 1.0 0.013 16.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJP64546.1 - 6.8e-05 23.4 5.9 0.019 15.6 1.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJP64546.1 - 0.00095 18.8 0.1 2.1 8.1 0.0 2.7 3 0 0 3 3 3 2 TPR repeat DUF357 PF04010.13 EJP64546.1 - 0.0054 16.8 0.1 0.016 15.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF357) TPR_6 PF13174.6 EJP64546.1 - 0.0058 17.2 5.1 0.23 12.2 0.2 3.4 4 0 0 4 4 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP64546.1 - 0.02 15.1 1.1 0.61 10.3 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EJP64546.1 - 0.04 14.1 0.7 1 9.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP64546.1 - 0.075 13.9 8.7 3.1 8.9 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat CPT PF07931.12 EJP64546.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TPR_7 PF13176.6 EJP64546.1 - 0.24 11.5 1.7 2.8 8.2 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EJP64546.1 - 0.66 10.3 5.4 2.8 8.3 1.2 2.7 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EJP64546.1 - 5.6 7.9 5.9 3.9 8.4 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Ribul_P_3_epim PF00834.19 EJP64547.1 - 1.6e-59 200.7 0.0 1.4e-58 197.6 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 EJP64547.1 - 0.025 13.9 0.3 0.041 13.2 0.3 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 EJP64547.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SQHop_cyclase_C PF13243.6 EJP64548.1 - 2.3e-49 168.2 0.9 1.7e-44 152.2 1.3 2.4 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EJP64548.1 - 1.4e-41 142.5 4.1 1.8e-36 125.7 0.1 3.1 4 0 0 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EJP64548.1 - 2e-29 101.0 8.5 2.5e-09 36.7 0.2 5.3 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EJP64548.1 - 0.0011 18.1 0.0 0.031 13.3 0.0 2.5 2 0 0 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 EJP64548.1 - 0.01 15.2 0.0 1.4 8.2 0.0 3.2 3 0 0 3 3 3 0 Pectic acid lyase Ank_5 PF13857.6 EJP64549.1 - 1.4e-12 47.6 0.0 8.7e-09 35.5 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP64549.1 - 2.9e-11 43.8 0.1 2.4e-10 40.9 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP64549.1 - 5.1e-08 33.3 0.0 5e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP64549.1 - 6e-07 29.3 0.0 0.00069 19.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EJP64549.1 - 3e-06 27.4 0.3 0.00032 21.0 0.3 2.6 3 0 0 3 3 3 1 Ankyrin repeat YlbD_coat PF14071.6 EJP64549.1 - 0.05 13.9 0.0 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 Putative coat protein Fungal_trans PF04082.18 EJP64550.1 - 2.1e-52 177.8 0.7 3e-52 177.3 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EJP64550.1 - 4.2e-08 33.2 7.0 0.0023 18.3 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP64550.1 - 0.00069 20.3 5.7 0.46 11.5 0.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EJP64550.1 - 0.0036 17.7 3.7 0.0065 16.9 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger double domain MHYT PF03707.16 EJP64551.1 - 0.012 15.7 0.4 0.17 12.1 0.3 2.1 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Tetraspanin PF00335.20 EJP64551.1 - 0.024 14.4 0.4 0.031 14.0 0.4 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4291 PF14124.6 EJP64552.1 - 6.1e-69 231.5 0.0 7e-69 231.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) TOBE_2 PF08402.10 EJP64552.1 - 0.049 13.8 0.4 0.13 12.5 0.1 1.8 2 1 0 2 2 2 0 TOBE domain DUF3378 PF11858.8 EJP64552.1 - 0.12 12.5 0.3 0.22 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) VPS9 PF02204.18 EJP64553.1 - 7.3e-31 106.5 0.0 1.4e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EJP64553.1 - 3.4e-16 59.3 0.3 7.9e-16 58.1 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EJP64553.1 - 9.5e-05 22.0 0.0 0.00098 18.8 0.0 2.4 2 0 0 2 2 2 1 CUE domain TRP PF06011.12 EJP64554.1 - 6.1e-132 440.3 14.3 7.8e-132 440.0 14.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EJP64554.1 - 7e-43 146.3 2.0 1.1e-42 145.7 2.0 1.3 1 0 0 1 1 1 1 ML-like domain DiS_P_DiS PF06750.13 EJP64554.1 - 0.11 12.6 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Orf78 PF06024.12 EJP64554.1 - 0.3 11.4 2.7 0.69 10.3 0.6 2.4 2 0 0 2 2 2 0 Orf78 (ac78) zf-C2H2 PF00096.26 EJP64555.1 - 1.2e-06 28.6 22.4 0.00055 20.2 0.3 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP64555.1 - 0.0023 18.6 0.5 0.0023 18.6 0.5 4.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EJP64555.1 - 0.021 14.8 0.1 0.021 14.8 0.1 3.5 5 0 0 5 5 5 0 C2H2-type zinc finger Transformer PF06495.11 EJP64555.1 - 0.12 12.5 6.4 0.31 11.1 6.4 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein DUF202 PF02656.15 EJP64556.1 - 6.2e-06 26.6 3.9 8.9e-06 26.1 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SnoaL_4 PF13577.6 EJP64557.1 - 1.5e-18 67.2 0.2 1.9e-18 66.8 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EJP64557.1 - 0.023 15.3 0.1 0.17 12.5 0.1 2.0 2 0 0 2 2 2 0 SnoaL-like domain Zn_clus PF00172.18 EJP64558.1 - 0.0013 18.8 9.8 0.0022 18.1 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 EJP64559.1 - 1.6e-22 81.2 1.1 3.3e-22 80.2 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP64559.1 - 8.9e-10 38.6 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP64559.1 - 1.2e-07 31.3 0.1 2.4e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EJP64559.1 - 0.005 16.4 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 EJP64559.1 - 0.052 13.2 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.12 EJP64559.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) NMO PF03060.15 EJP64561.1 - 1.6e-48 165.9 0.3 2.3e-48 165.3 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EJP64561.1 - 7.1e-10 38.4 0.3 6.7e-09 35.2 0.3 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EJP64561.1 - 2.5e-05 23.5 1.2 4.4e-05 22.7 1.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DEAD PF00270.29 EJP64562.1 - 1.6e-46 158.3 0.0 3.6e-46 157.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP64562.1 - 9e-25 87.2 0.0 7.4e-24 84.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EJP64562.1 - 2.1e-17 63.1 0.1 5.3e-17 61.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 EJP64562.1 - 1e-05 24.9 0.0 2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EJP64562.1 - 4.3e-05 23.6 0.0 0.00016 21.8 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KAP_NTPase PF07693.14 EJP64562.1 - 0.056 12.7 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain Pox_Ag35 PF03286.14 EJP64562.1 - 0.18 11.6 14.2 0.32 10.7 14.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 EJP64562.1 - 0.34 9.1 11.3 0.47 8.6 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 EJP64562.1 - 1 9.2 10.8 2.4 8.0 10.8 1.8 1 1 0 1 1 1 0 Sigma-70, non-essential region Lin-8 PF03353.15 EJP64562.1 - 1.2 8.7 8.8 0.85 9.1 6.1 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Smg4_UPF3 PF03467.15 EJP64562.1 - 1.3 9.0 8.4 0.73 9.8 6.3 1.7 2 0 0 2 2 2 0 Smg-4/UPF3 family FAD_binding_4 PF01565.23 EJP64563.1 - 1.3e-14 54.1 0.1 3.8e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain ABC_tran PF00005.27 EJP64564.1 - 1.2e-39 136.0 0.0 1.5e-18 67.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP64564.1 - 4.4e-26 92.2 20.7 1.7e-22 80.4 9.0 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP64564.1 - 1.5e-07 31.1 3.5 0.065 12.7 0.6 3.9 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP64564.1 - 2.8e-05 24.1 1.5 1.6 8.4 0.1 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EJP64564.1 - 0.00069 19.8 3.7 3.4 7.9 0.0 4.2 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EJP64564.1 - 0.0019 18.6 0.4 2.7 8.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EJP64564.1 - 0.0031 17.8 0.8 4.8 7.5 0.1 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EJP64564.1 - 0.0036 17.2 0.0 0.6 10.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EJP64564.1 - 0.0067 16.1 1.9 0.78 9.5 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJP64564.1 - 0.014 15.5 0.2 4.7 7.3 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EJP64564.1 - 0.034 14.7 1.8 0.22 12.0 0.1 2.5 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EJP64564.1 - 0.063 12.3 0.4 2 7.4 0.3 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EJP64564.1 - 0.09 12.7 0.0 9.7 6.0 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MobB PF03205.14 EJP64564.1 - 0.1 12.5 0.6 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EJP64564.1 - 0.25 10.9 3.1 5 6.7 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EJP64564.1 - 0.36 10.9 5.6 1.9 8.5 0.3 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 EJP64564.1 - 0.81 9.6 5.0 19 5.1 0.1 3.4 3 0 0 3 3 3 0 NACHT domain DUF4083 PF13314.6 EJP64564.1 - 0.85 9.6 2.7 4.6 7.3 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF1430 PF07242.11 EJP64564.1 - 9.1 6.6 7.3 2.4 8.5 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) ABC_tran PF00005.27 EJP64566.1 - 1.8e-39 135.4 0.2 1.3e-24 87.2 0.2 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP64566.1 - 5.2e-39 134.5 32.3 4.8e-33 115.0 9.7 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 EJP64566.1 - 2.5e-11 43.9 4.8 0.026 14.3 0.1 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP64566.1 - 1.2e-10 41.3 8.1 0.00026 20.5 1.2 4.4 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJP64566.1 - 1.6e-07 31.6 0.1 0.0044 17.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJP64566.1 - 4.5e-06 26.3 0.1 0.11 12.3 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJP64566.1 - 3.6e-05 23.8 0.2 0.35 10.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EJP64566.1 - 5.1e-05 23.2 0.0 0.0047 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EJP64566.1 - 0.00016 22.1 0.1 1.1 9.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EJP64566.1 - 0.00017 21.0 0.2 0.25 10.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 EJP64566.1 - 0.00058 19.8 4.0 0.48 10.3 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_23 PF13476.6 EJP64566.1 - 0.0017 18.9 1.3 0.11 13.0 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 EJP64566.1 - 0.0031 17.3 0.1 0.021 14.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EJP64566.1 - 0.0036 17.0 1.1 2 8.1 0.3 3.5 4 0 0 4 4 3 1 IstB-like ATP binding protein T2SSE PF00437.20 EJP64566.1 - 0.0055 15.8 0.1 0.64 9.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.9 EJP64566.1 - 0.0092 15.3 0.0 0.95 8.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EJP64566.1 - 0.01 15.4 0.1 4.3 6.8 0.0 3.0 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EJP64566.1 - 0.011 15.6 0.3 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EJP64566.1 - 0.023 14.4 3.0 7.6 6.2 0.0 4.4 5 0 0 5 5 5 0 AAA domain Dynamin_N PF00350.23 EJP64566.1 - 0.025 14.6 0.1 9.1 6.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 EJP64566.1 - 0.031 14.4 0.7 0.43 10.6 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 EJP64566.1 - 0.049 13.2 0.6 3.4 7.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 EJP64566.1 - 0.049 13.1 0.4 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.6 EJP64566.1 - 0.051 14.1 0.1 9.3 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EJP64566.1 - 0.11 12.8 0.7 0.65 10.3 0.2 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2474 PF10617.9 EJP64566.1 - 0.68 9.8 5.6 3.5 7.5 5.6 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Rubis-subs-bind PF09273.11 EJP64567.1 - 7e-21 75.3 0.2 1.1e-20 74.6 0.2 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EJP64567.1 - 8.1e-10 39.3 0.0 1.3e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 SET domain DNA_gyraseA_C PF03989.13 EJP64567.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller Metal_resist PF13801.6 EJP64570.1 - 0.0037 17.4 0.3 0.0044 17.2 0.3 1.1 1 0 0 1 1 1 1 Heavy-metal resistance CENP-K PF11802.8 EJP64570.1 - 0.017 14.7 0.1 0.018 14.6 0.1 1.0 1 0 0 1 1 1 0 Centromere-associated protein K DUF5444 PF17519.2 EJP64570.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5444) Ank_2 PF12796.7 EJP64572.1 - 1.2e-49 166.8 9.6 2.9e-14 53.4 0.2 6.8 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP64572.1 - 2.8e-47 158.5 4.3 1e-13 51.5 0.0 9.1 7 2 2 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP64572.1 - 1.9e-45 147.6 5.2 4.7e-05 23.5 0.0 11.6 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 EJP64572.1 - 6.2e-33 112.4 8.4 3.9e-10 39.8 0.0 9.9 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 EJP64572.1 - 3.3e-29 100.0 13.6 5.1e-06 26.7 0.0 10.7 11 0 0 11 11 11 7 Ankyrin repeat Shigella_OspC PF06128.11 EJP64572.1 - 0.056 13.2 0.1 4.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Shigella flexneri OspC protein Catalase PF00199.19 EJP64573.1 - 7.6e-05 22.0 0.1 0.024 13.7 0.0 2.3 2 0 0 2 2 2 2 Catalase Gpr1_Fun34_YaaH PF01184.19 EJP64575.1 - 5.1e-41 140.6 15.6 6.6e-41 140.2 15.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ank_2 PF12796.7 EJP64576.1 - 1.5e-39 134.4 4.4 9.8e-14 51.7 0.3 4.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP64576.1 - 1.1e-37 127.9 14.6 2.7e-08 34.2 0.1 5.7 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP64576.1 - 3.7e-29 97.5 10.5 0.00045 20.5 0.1 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 EJP64576.1 - 4.5e-26 90.1 23.3 0.00053 20.3 0.4 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EJP64576.1 - 5e-16 58.6 11.6 0.00041 20.6 0.2 6.7 3 1 3 6 6 6 4 Ankyrin repeats (many copies) DUF1843 PF08898.10 EJP64576.1 - 0.0028 18.1 1.6 0.035 14.6 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) Acyl-CoA_dh_2 PF08028.11 EJP64577.1 - 3.1e-13 50.2 0.1 5e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EJP64577.1 - 3.1e-06 27.3 0.1 1.1e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EJP64577.1 - 0.00026 21.6 0.0 0.00056 20.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EJP64577.1 - 0.011 16.0 0.1 0.021 15.0 0.1 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 EJP64578.1 - 2.8e-18 65.8 22.6 1e-09 38.3 7.2 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP64578.1 - 8e-15 54.6 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PARP PF00644.20 EJP64579.1 - 8.2e-59 198.5 0.2 2e-58 197.2 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EJP64579.1 - 1.4e-40 138.5 0.0 1.1e-39 135.6 0.0 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EJP64579.1 - 1.7e-23 82.5 0.0 3.8e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 WGR domain BRCT_2 PF16589.5 EJP64579.1 - 0.00016 22.0 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EJP64579.1 - 0.015 15.2 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 EJP64579.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EJP64579.1 - 0.025 14.9 0.0 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain NHL PF01436.21 EJP64579.1 - 0.084 12.9 0.3 0.24 11.5 0.3 1.8 1 0 0 1 1 1 0 NHL repeat GAGA_bind PF06217.12 EJP64579.1 - 0.43 10.8 5.8 0.69 10.1 5.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Hap4_Hap_bind PF10297.9 EJP64582.1 - 1.5e-08 34.5 6.9 1.5e-08 34.5 6.9 2.3 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EJP64582.1 - 1.4e-06 28.3 4.5 3.6e-06 27.0 4.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor dsrm PF00035.26 EJP64582.1 - 0.11 13.2 0.0 0.38 11.5 0.0 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif bZIP_2 PF07716.15 EJP64582.1 - 0.23 11.6 11.6 0.1 12.7 1.4 3.1 2 1 1 3 3 3 0 Basic region leucine zipper RBM39linker PF15519.6 EJP64582.1 - 0.5 11.5 0.0 0.5 11.5 0.0 3.3 4 0 0 4 4 4 0 linker between RRM2 and RRM3 domains in RBM39 protein ABC_tran PF00005.27 EJP64583.1 - 8.2e-49 165.6 0.0 4.3e-29 101.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP64583.1 - 2e-31 109.6 11.4 2.7e-22 79.7 7.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP64583.1 - 6.2e-12 45.4 1.0 5.6e-05 22.7 0.1 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EJP64583.1 - 1.4e-09 37.4 0.1 0.0002 20.6 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 EJP64583.1 - 1.2e-08 35.1 2.9 0.49 10.1 0.0 4.5 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EJP64583.1 - 7.7e-07 29.4 0.6 0.018 15.2 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 EJP64583.1 - 3.5e-06 27.3 0.0 0.18 12.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EJP64583.1 - 8.9e-06 25.5 0.4 1.7 8.4 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_29 PF13555.6 EJP64583.1 - 9.9e-06 25.2 0.2 0.2 11.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EJP64583.1 - 1.4e-05 25.7 0.1 0.1 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJP64583.1 - 2.6e-05 24.7 0.1 0.21 11.9 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EJP64583.1 - 0.00013 22.0 0.7 0.026 14.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 EJP64583.1 - 0.00014 21.0 0.7 0.1 11.5 0.1 2.4 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 EJP64583.1 - 0.00015 21.7 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EJP64583.1 - 0.00026 20.7 0.2 0.97 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 EJP64583.1 - 0.00047 19.8 1.2 0.76 9.3 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EJP64583.1 - 0.0025 17.2 0.1 2.4 7.5 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.12 EJP64583.1 - 0.0025 17.8 0.7 2.2 8.2 0.1 2.8 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 EJP64583.1 - 0.0039 16.8 0.1 1.6 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EJP64583.1 - 0.007 15.7 0.1 2.6 7.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.7 EJP64583.1 - 0.0079 15.2 0.0 3.4 6.5 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain NB-ARC PF00931.22 EJP64583.1 - 0.0086 15.3 0.5 0.23 10.6 0.1 2.9 3 0 0 3 3 3 1 NB-ARC domain DUF3645 PF12359.8 EJP64583.1 - 0.022 14.1 0.7 0.5 9.8 0.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF3645) MeaB PF03308.16 EJP64583.1 - 0.026 13.5 0.4 0.35 9.8 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 EJP64583.1 - 0.039 13.2 0.5 0.28 10.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EJP64583.1 - 0.044 14.2 0.2 19 5.7 0.0 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EJP64583.1 - 0.047 13.6 1.0 0.92 9.4 0.2 2.5 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 EJP64583.1 - 0.051 13.3 0.0 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EJP64583.1 - 0.052 13.1 0.1 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EJP64583.1 - 0.067 13.2 1.0 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Dynamin family MobB PF03205.14 EJP64583.1 - 0.084 12.8 1.0 0.83 9.6 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 EJP64583.1 - 0.11 12.9 0.1 15 6.0 0.0 2.9 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 EJP64583.1 - 0.11 12.5 0.1 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EJP64583.1 - 0.16 12.1 0.0 23 5.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EJP64583.1 - 0.17 11.3 0.2 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein DAP3 PF10236.9 EJP64583.1 - 0.2 10.8 2.7 5.5 6.1 0.1 3.5 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.15 EJP64583.1 - 0.21 11.6 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EJP64583.1 - 0.26 11.8 0.9 22 5.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EJP64583.1 - 0.26 10.9 0.1 1.8 8.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain HET PF06985.11 EJP64584.1 - 1.3e-17 64.5 0.0 2.1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cons_hypoth95 PF03602.15 EJP64585.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GGACT PF06094.12 EJP64586.1 - 0.0011 19.5 1.9 0.012 16.3 1.9 2.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like GTP_cyclohydroI PF01227.22 EJP64587.1 - 4.9e-74 247.6 0.3 6.9e-74 247.1 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EJP64587.1 - 0.0014 18.7 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 QueF-like protein Methyltransf_PK PF05891.12 EJP64588.1 - 1.8e-69 233.6 0.0 2e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EJP64588.1 - 1.2e-05 25.9 0.0 2.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP64588.1 - 0.0013 19.3 0.0 0.0023 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain BMC PF00936.19 EJP64588.1 - 0.0086 16.0 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 BMC domain Methyltransf_12 PF08242.12 EJP64588.1 - 0.01 16.5 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF1871 PF08958.10 EJP64588.1 - 0.035 14.4 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) Methyltransf_2 PF00891.18 EJP64588.1 - 0.056 12.7 0.1 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain SVWC PF15430.6 EJP64589.1 - 0.0004 20.6 4.6 0.00051 20.2 4.6 1.2 1 0 0 1 1 1 1 Single domain von Willebrand factor type C TAFII28 PF04719.14 EJP64590.1 - 2.7e-31 107.5 0.0 5.3e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region PSD1 PF07587.11 EJP64590.1 - 0.0023 17.5 0.4 0.0044 16.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1553) DUF3682 PF12446.8 EJP64590.1 - 2.3 8.7 22.7 0.051 14.0 13.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3682) Muted PF14942.6 EJP64591.1 - 0.084 13.2 2.1 11 6.4 0.0 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein SBF PF01758.16 EJP64592.1 - 2.2e-47 161.3 11.0 2.2e-47 161.3 11.0 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family Endotoxin_N PF03945.14 EJP64593.1 - 2.5e-19 69.9 0.0 2.9e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain Jacalin PF01419.17 EJP64593.1 - 0.012 15.5 0.2 0.073 13.0 0.0 2.2 2 0 0 2 2 2 0 Jacalin-like lectin domain DCD PF06559.11 EJP64593.1 - 0.031 13.1 0.3 0.05 12.4 0.3 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) OTT_1508_deam PF14441.6 EJP64594.1 - 3.6e-16 58.9 0.2 8.1e-16 57.8 0.2 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF4872 PF16169.5 EJP64594.1 - 0.057 13.2 0.1 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) DUF5414 PF17435.2 EJP64594.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5414) FliS PF02561.14 EJP64594.1 - 0.11 12.8 0.0 0.75 10.1 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein FliS SurE PF01975.17 EJP64595.1 - 9.4e-26 90.8 0.0 1.4e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_4 PF13439.6 EJP64595.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 tRNA-synt_1c PF00749.21 EJP64596.1 - 1.6e-103 345.9 0.1 2e-103 345.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EJP64596.1 - 3.2e-39 134.6 0.0 5.3e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 EJP64596.1 - 0.028 13.8 0.3 0.067 12.5 0.1 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF2730 PF10805.8 EJP64596.1 - 0.13 12.4 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Ribosomal_L1 PF00687.21 EJP64597.1 - 3.8e-27 95.3 0.0 5.2e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.11 EJP64598.1 - 2.4e-27 95.7 0.0 4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 EJP64598.1 - 4e-05 23.8 0.1 0.00028 21.1 0.0 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 EJP64598.1 - 0.04 14.0 0.1 0.21 11.7 0.0 2.3 2 1 1 3 3 3 0 Vps51/Vps67 NOA36 PF06524.12 EJP64598.1 - 0.051 12.9 3.2 0.077 12.3 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein Fimbrial_PilY2 PF14481.6 EJP64598.1 - 0.071 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Vps54_N PF10475.9 EJP64598.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex FAM176 PF14851.6 EJP64598.1 - 0.36 10.5 5.6 0.66 9.6 5.5 1.5 1 1 0 1 1 1 0 FAM176 family S-antigen PF05756.11 EJP64598.1 - 1.3 9.4 3.4 2.9 8.3 3.4 1.5 1 0 0 1 1 1 0 S-antigen protein DUF4611 PF15387.6 EJP64598.1 - 4.1 7.7 12.0 0.16 12.2 5.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Fungal_trans PF04082.18 EJP64599.1 - 4.2e-23 81.7 0.0 7e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64599.1 - 9.1e-09 35.3 14.1 9.1e-09 35.3 14.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3623 PF12291.8 EJP64599.1 - 0.0022 17.2 0.1 0.0036 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3623) ERO1 PF04137.15 EJP64599.1 - 0.022 14.0 0.2 0.042 13.1 0.2 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Beta_helix PF13229.6 EJP64600.1 - 2e-11 44.0 23.4 3.2e-05 23.8 23.4 4.1 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EJP64600.1 - 1.1e-06 28.1 8.8 0.00021 20.6 0.5 3.4 1 1 1 3 3 3 2 Periplasmic copper-binding protein (NosD) DUF2264 PF10022.9 EJP64601.1 - 3e-130 434.4 1.8 3.7e-130 434.1 1.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.24 EJP64602.1 - 7.4e-83 278.9 18.3 1e-82 278.4 18.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP64602.1 - 6.4e-25 87.8 32.8 5.1e-24 84.9 30.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 EJP64602.1 - 3.4e-07 29.7 0.0 6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 TRI12 PF06609.13 EJP64602.1 - 0.00095 17.7 0.2 0.00095 17.7 0.2 2.5 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 EJP64602.1 - 0.042 14.4 0.3 0.12 13.0 0.3 1.7 1 0 0 1 1 1 0 Phage holin family 2 EMP70 PF02990.16 EJP64602.1 - 0.21 10.2 5.8 0.24 10.1 1.0 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 PLU-1 PF08429.11 EJP64603.1 - 1.1e-111 373.3 10.2 6e-108 361.0 8.9 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EJP64603.1 - 3.8e-43 146.5 0.4 9.2e-43 145.3 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EJP64603.1 - 1.5e-21 76.9 0.1 3.5e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 EJP64603.1 - 7e-16 57.9 30.2 1.5e-10 40.8 4.2 3.1 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 EJP64603.1 - 8.3e-15 54.5 1.8 1.9e-14 53.3 1.8 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 EJP64603.1 - 1.1e-11 45.0 7.2 3.4e-11 43.4 7.2 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 EJP64603.1 - 0.00013 21.7 6.0 0.0034 17.0 0.3 2.8 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 EJP64603.1 - 0.69 10.1 19.5 0.38 10.9 5.6 3.3 2 0 0 2 2 2 0 PHD-finger PHD_2 PF13831.6 EJP64603.1 - 4 7.1 11.5 0.094 12.3 0.9 2.8 2 0 0 2 2 2 0 PHD-finger His_Phos_2 PF00328.22 EJP64604.1 - 3.1e-25 89.3 0.0 4.1e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Hydrophobin PF01185.18 EJP64605.1 - 2.5e-12 47.2 10.5 3.3e-12 46.8 10.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Glyco_transf_25 PF01755.17 EJP64606.1 - 5.5e-13 49.2 0.0 5.1e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) LSM14 PF12701.7 EJP64606.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Scd6-like Sm domain MGC-24 PF05283.11 EJP64607.1 - 0.0097 16.4 1.9 0.018 15.5 1.9 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gram_pos_anchor PF00746.21 EJP64607.1 - 0.038 13.9 0.9 0.079 12.9 0.9 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4366 PF14283.6 EJP64607.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) FeoB_associated PF12669.7 EJP64607.1 - 0.18 12.2 0.2 0.36 11.3 0.2 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein ABC_tran PF00005.27 EJP64608.1 - 6.2e-32 111.0 0.0 1.3e-31 110.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EJP64608.1 - 1.8e-18 67.2 2.4 1.8e-18 67.2 2.4 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EJP64608.1 - 0.00086 18.8 0.0 0.023 14.1 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EJP64608.1 - 0.0023 18.3 0.0 0.0083 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EJP64608.1 - 0.0024 17.2 0.1 0.0024 17.2 0.1 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 EJP64608.1 - 0.024 14.4 0.1 0.08 12.7 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 EJP64608.1 - 0.028 13.4 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.6 EJP64608.1 - 0.055 13.7 0.1 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EJP64608.1 - 0.066 13.8 0.3 0.25 11.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EJP64608.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EJP64608.1 - 0.091 12.8 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 EJP64608.1 - 0.13 12.4 0.5 0.29 11.2 0.2 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain HemY_N PF07219.13 EJP64608.1 - 0.33 11.2 3.9 0.54 10.5 1.9 2.4 2 0 0 2 2 2 0 HemY protein N-terminus Pkinase PF00069.25 EJP64610.1 - 1e-12 48.0 0.0 2.6e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64610.1 - 0.00067 19.0 0.0 0.0019 17.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP64610.1 - 0.018 15.0 0.0 0.081 12.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pyr_redox PF00070.27 EJP64611.1 - 0.15 12.6 0.3 0.48 11.0 0.1 1.9 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CREPT PF16566.5 EJP64611.1 - 0.3 11.3 2.4 1.1 9.5 0.5 2.1 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour GIY-YIG PF01541.24 EJP64612.1 - 1.1e-12 48.0 0.0 2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.6 EJP64612.1 - 0.015 15.5 2.6 0.025 14.7 2.6 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EJP64612.1 - 0.061 13.6 3.2 0.098 12.9 3.2 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain T5orf172 PF10544.9 EJP64612.1 - 0.065 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 T5orf172 domain C1_1 PF00130.22 EJP64612.1 - 3.4 7.6 6.8 0.81 9.6 2.1 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EJP64612.1 - 4.6 7.2 9.2 0.33 10.9 2.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3449 PF11931.8 EJP64613.1 - 1e-77 260.1 0.5 1e-77 260.1 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EJP64613.1 - 7.4e-26 90.5 0.3 1.7e-25 89.3 0.3 1.7 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EJP64613.1 - 2e-09 37.2 0.2 4.1e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EJP64613.1 - 6.9e-09 35.8 3.0 5.7e-07 29.7 0.7 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EJP64613.1 - 1.1e-08 35.2 4.5 1.1e-07 32.0 1.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EJP64613.1 - 0.0028 17.9 3.8 0.041 14.2 0.9 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 EJP64613.1 - 0.017 15.2 0.4 0.017 15.2 0.4 2.8 3 1 0 3 3 3 0 DBF zinc finger zf-C2H2_4 PF13894.6 EJP64613.1 - 0.025 15.4 0.9 3 8.9 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C4H2 PF10146.9 EJP64613.1 - 0.04 14.2 0.5 0.04 14.2 0.5 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein DUF951 PF06107.11 EJP64613.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) PRP9_N PF16958.5 EJP64613.1 - 0.3 11.1 20.3 0.053 13.6 1.7 3.4 2 1 1 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2 PF00096.26 EJP64613.1 - 1.4 9.5 3.5 3.9 8.1 0.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.29 EJP64614.1 - 1.6e-42 145.2 0.2 2.8e-42 144.5 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP64614.1 - 1.8e-33 115.2 0.0 6.7e-33 113.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EJP64614.1 - 0.00055 19.7 0.1 0.00084 19.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP64614.1 - 0.0013 19.1 0.1 0.012 15.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EJP64614.1 - 0.0013 18.7 0.0 0.0028 17.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EJP64614.1 - 0.051 13.4 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF5393 PF17371.2 EJP64614.1 - 0.067 11.3 0.1 0.11 10.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Flavi_DEAD PF07652.14 EJP64614.1 - 0.068 13.1 1.1 0.25 11.3 0.1 2.4 2 1 1 3 3 3 0 Flavivirus DEAD domain AAA_22 PF13401.6 EJP64614.1 - 0.072 13.4 0.5 0.24 11.7 0.5 1.8 1 1 0 1 1 1 0 AAA domain MCRA PF06100.11 EJP64615.1 - 5.4e-217 721.5 0.0 6.3e-217 721.2 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 EJP64615.1 - 1.3e-07 31.7 0.0 2.8e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP64615.1 - 0.00011 22.0 0.1 0.0014 18.3 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP64615.1 - 0.075 12.2 0.0 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EJP64616.1 - 2.3e-15 56.7 0.0 3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64616.1 - 0.00096 18.5 0.1 0.0026 17.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2855 PF11017.8 EJP64617.1 - 2.9e-85 287.0 0.0 3.4e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) DUF3112 PF11309.8 EJP64618.1 - 2.6e-05 23.8 0.1 2.6e-05 23.8 0.1 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF3112) ketoacyl-synt PF00109.26 EJP64619.1 - 3.4e-79 266.0 0.0 7.2e-79 264.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EJP64619.1 - 4e-60 203.5 0.4 4.8e-59 200.0 0.0 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 EJP64619.1 - 9.7e-36 122.4 0.0 2.4e-35 121.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EJP64619.1 - 1.8e-30 106.5 0.0 5.1e-30 105.1 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.25 EJP64619.1 - 3.1e-24 85.1 10.0 3e-13 49.9 0.8 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 EJP64619.1 - 2.8e-21 76.7 0.0 8.1e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.6 EJP64619.1 - 1.6e-20 73.6 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 EJP64619.1 - 4.7e-08 33.9 4.6 2.6e-06 28.2 1.6 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 EJP64619.1 - 5.6e-07 30.0 0.0 2.6e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EJP64619.1 - 0.0005 19.5 0.0 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Metallophos PF00149.28 EJP64620.1 - 3.4e-08 34.3 0.2 4.6e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MbtH PF03621.13 EJP64620.1 - 0.00091 18.6 0.3 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 MbtH-like protein adh_short_C2 PF13561.6 EJP64622.1 - 1.7e-54 184.9 3.7 3.4e-54 183.9 3.7 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP64622.1 - 3.5e-50 170.2 3.0 4.5e-50 169.8 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP64622.1 - 6.5e-15 55.5 2.2 8.4e-15 55.1 2.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP64622.1 - 0.0023 17.4 0.2 0.01 15.3 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EJP64622.1 - 0.034 13.5 0.1 0.23 10.8 0.0 2.2 2 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Dehalogenase PF13486.6 EJP64622.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Reductive dehalogenase subunit Shikimate_DH PF01488.20 EJP64622.1 - 0.66 10.0 2.6 2 8.5 1.2 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Scytalone_dh PF02982.14 EJP64623.1 - 3.4e-73 244.7 0.5 4.3e-73 244.4 0.5 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EJP64623.1 - 3.7e-08 33.6 0.4 4.6e-08 33.2 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain Mucin PF01456.17 EJP64624.1 - 0.0019 18.2 16.1 0.0028 17.7 16.1 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein FSA_C PF10479.9 EJP64624.1 - 6.7 4.7 11.6 9.5 4.2 11.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus adh_short PF00106.25 EJP64626.1 - 4.3e-31 107.9 0.3 5.7e-31 107.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP64626.1 - 2.7e-28 99.1 0.1 3.5e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP64626.1 - 8.1e-05 22.6 0.2 0.00011 22.1 0.2 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EJP64626.1 - 0.0095 15.1 0.1 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Syncollin PF15138.6 EJP64627.1 - 0.00053 20.2 0.1 0.00085 19.5 0.1 1.4 1 1 0 1 1 1 1 Syncollin Crystall PF00030.19 EJP64627.1 - 0.041 14.1 0.0 0.072 13.3 0.0 1.4 1 1 0 1 1 1 0 Beta/Gamma crystallin ACT_3 PF10000.9 EJP64628.1 - 1.1e-22 79.7 0.1 1.7e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 EJP64628.1 - 3.6e-06 26.7 0.0 5.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 ACT domain Thioredoxin PF00085.20 EJP64629.1 - 1.3e-30 105.4 0.0 2.2e-24 85.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EJP64629.1 - 3.4e-07 30.7 0.1 0.026 15.0 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EJP64629.1 - 1.1e-05 25.0 0.0 0.00021 20.8 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EJP64629.1 - 0.00023 21.4 0.0 6.4 7.2 0.0 4.7 3 2 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 EJP64629.1 - 0.001 19.0 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 AhpC/TSA family ERp29_N PF07912.13 EJP64629.1 - 0.0025 18.0 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 1 ERp29, N-terminal domain TraF PF13728.6 EJP64629.1 - 0.029 14.2 0.0 0.092 12.6 0.0 4.5 4 1 0 4 4 4 0 F plasmid transfer operon protein QSOX_Trx1 PF18108.1 EJP64629.1 - 0.039 14.1 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 QSOX Trx-like domain Troponin-I_N PF11636.8 EJP64629.1 - 0.052 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 Thioredoxin_3 PF13192.6 EJP64629.1 - 0.065 13.3 0.2 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin domain RNase_PH PF01138.21 EJP64630.1 - 1.1e-33 116.6 0.2 1.5e-33 116.1 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Alpha-amyl_C PF09071.10 EJP64630.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Alpha-amylase, C terminal ADH_N PF08240.12 EJP64631.1 - 1.4e-26 92.5 2.4 2.7e-26 91.6 2.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP64631.1 - 1.3e-19 70.5 0.1 2.2e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP64631.1 - 1.7e-05 25.9 0.0 3.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EJP64631.1 - 0.026 13.8 0.5 0.059 12.6 0.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_trans_4_2 PF13477.6 EJP64631.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like ETC_C1_NDUFA4 PF04800.12 EJP64631.1 - 0.24 11.6 0.2 11 6.3 0.0 2.4 2 0 0 2 2 2 0 ETC complex I subunit conserved region RSN1_7TM PF02714.15 EJP64632.1 - 4.3e-82 275.5 17.4 8.8e-82 274.5 17.4 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EJP64632.1 - 6.7e-44 149.4 1.6 2.1e-43 147.8 1.6 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 EJP64632.1 - 3.9e-23 81.5 0.4 1.3e-22 79.7 0.1 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 EJP64632.1 - 7.1e-21 75.2 5.6 3.5e-20 72.9 5.6 2.1 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Myc_N PF01056.18 EJP64632.1 - 7.9 6.3 13.1 0.087 12.7 3.0 2.1 2 0 0 2 2 2 0 Myc amino-terminal region DHDPS PF00701.22 EJP64633.1 - 3.8e-52 176.8 0.0 4.6e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family NMO PF03060.15 EJP64633.1 - 0.066 12.6 0.6 0.1 11.9 0.6 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase PEP_mutase PF13714.6 EJP64633.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase BKACE PF05853.12 EJP64633.1 - 0.13 11.5 0.0 3 7.1 0.0 2.2 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme OPT PF03169.15 EJP64634.1 - 2.9e-86 290.5 45.6 3.4e-86 290.2 45.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short_C2 PF13561.6 EJP64635.1 - 1.3e-59 201.6 0.6 1.5e-59 201.4 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP64635.1 - 2e-38 131.8 1.7 2.4e-38 131.6 1.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP64635.1 - 1e-14 54.8 0.5 1.5e-14 54.3 0.5 1.2 1 0 0 1 1 1 1 KR domain Mrr_cat PF04471.12 EJP64635.1 - 0.077 13.0 0.5 0.27 11.3 0.2 2.1 2 1 0 2 2 2 0 Restriction endonuclease Apc13p PF05839.11 EJP64636.1 - 3.6e-33 113.6 0.1 4.1e-33 113.4 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.16 EJP64637.1 - 1.3e-42 144.9 0.0 1.6e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-BED PF02892.15 EJP64639.1 - 0.25 11.4 3.2 0.52 10.4 3.2 1.5 1 0 0 1 1 1 0 BED zinc finger Dimer_Tnp_hAT PF05699.14 EJP64640.1 - 7.9e-14 51.2 0.0 2.5e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FA_desaturase PF00487.24 EJP64641.1 - 3.2e-12 46.8 33.3 3.2e-12 46.8 33.3 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Pkinase PF00069.25 EJP64642.1 - 2.4e-08 33.7 0.1 3.5e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64642.1 - 5.6e-07 29.1 0.0 8.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Phostensin PF13914.6 EJP64642.1 - 0.51 11.0 4.1 0.77 10.4 0.2 2.2 2 0 0 2 2 2 0 Phostensin PP1-binding and SH3-binding region MFS_1 PF07690.16 EJP64643.1 - 2.8e-41 141.6 65.8 2e-33 115.8 29.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP64643.1 - 2.4e-13 49.8 26.9 6.3e-13 48.4 11.7 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EJP64643.1 - 1e-06 27.9 24.2 2.7e-05 23.2 5.8 2.2 1 1 1 2 2 2 2 MFS_1 like family Zn_clus PF00172.18 EJP64644.1 - 0.00017 21.6 9.4 0.00017 21.6 9.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EJP64645.1 - 2.5e-30 105.6 0.1 3.4e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EJP64647.1 - 7.7e-11 41.5 0.5 1.4e-10 40.7 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64647.1 - 1.2e-08 34.9 8.0 2.6e-08 33.9 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEP PF00610.21 EJP64647.1 - 0.12 12.4 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ADH_N PF08240.12 EJP64648.1 - 0.00011 22.0 0.4 0.00043 20.1 0.3 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Lustrin_cystein PF14625.6 EJP64650.1 - 0.048 14.0 3.7 0.11 12.8 3.7 1.6 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Pigment_DH PF06324.11 EJP64650.1 - 0.089 12.9 0.3 0.23 11.6 0.3 1.6 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Sec63 PF02889.16 EJP64652.1 - 7.9e-12 44.9 0.0 1.1e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain HHH_5 PF14520.6 EJP64652.1 - 0.065 13.8 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peptidase_M4_C PF02868.15 EJP64653.1 - 4.3e-42 143.8 0.0 1.9e-41 141.8 0.0 2.0 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 EJP64653.1 - 2.8e-25 89.5 2.4 5.1e-25 88.7 2.4 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 EJP64653.1 - 1.1e-21 76.2 0.5 1.1e-14 53.8 0.3 2.5 2 0 0 2 2 2 2 Protealysin propeptide Peptidase_M13 PF01431.21 EJP64653.1 - 0.063 12.9 0.4 0.31 10.6 0.2 2.3 2 0 0 2 2 2 0 Peptidase family M13 IL11 PF07400.11 EJP64653.1 - 0.084 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Interleukin 11 Glyco_hydro_16 PF00722.21 EJP64655.1 - 6.7e-38 129.9 0.8 6.7e-38 129.9 0.8 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Apt1 PF10351.9 EJP64655.1 - 0.42 9.4 13.1 0.62 8.9 13.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SIR2 PF02146.17 EJP64656.1 - 5.8e-38 130.6 0.0 1.6e-37 129.1 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Peripla_BP_4 PF13407.6 EJP64656.1 - 0.054 13.0 0.1 0.082 12.5 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Glyco_hydro_92 PF07971.12 EJP64657.1 - 2.2e-140 468.7 0.0 2.6e-140 468.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EJP64657.1 - 1.9e-62 211.3 0.1 3.9e-62 210.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF2271 PF10029.9 EJP64657.1 - 0.00045 19.9 0.1 0.00096 18.8 0.1 1.5 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2271) HA PF03457.14 EJP64658.1 - 0.063 13.6 0.0 0.77 10.1 0.0 2.3 2 0 0 2 2 2 0 Helicase associated domain DUF572 PF04502.13 EJP64659.1 - 2.3e-64 218.1 0.0 2.6e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) CN_hydrolase PF00795.22 EJP64660.1 - 2.7e-33 115.4 0.0 3.2e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Tht1 PF04163.12 EJP64661.1 - 4.9e-05 22.3 1.3 4.9e-05 22.3 1.3 2.1 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein Snapin_Pallidin PF14712.6 EJP64661.1 - 1.5 9.3 9.6 0.23 11.9 2.2 2.8 2 1 0 2 2 2 0 Snapin/Pallidin HLH PF00010.26 EJP64662.1 - 6.8e-16 58.0 0.5 2.7e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain OmpH PF03938.14 EJP64662.1 - 0.08 13.3 0.6 0.13 12.6 0.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HOOK PF05622.12 EJP64662.1 - 0.12 10.5 0.2 0.18 9.9 0.2 1.1 1 0 0 1 1 1 0 HOOK protein AA_permease_2 PF13520.6 EJP64663.1 - 7.6e-37 127.1 52.5 9.2e-37 126.9 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP64663.1 - 3.9e-13 48.8 41.9 5.5e-13 48.3 41.9 1.2 1 0 0 1 1 1 1 Amino acid permease VIT1 PF01988.19 EJP64663.1 - 5.1 6.9 14.9 0.04 13.8 1.9 3.0 2 2 0 2 2 2 0 VIT family Peptidase_M24 PF00557.24 EJP64664.1 - 1.2e-48 165.5 0.0 1.7e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EJP64664.1 - 4e-37 126.7 0.0 6.2e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.10 EJP64665.1 - 5.7e-43 146.2 0.0 1.1e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 EJP64665.1 - 7.4e-21 74.0 0.2 1.3e-20 73.2 0.2 1.4 1 0 0 1 1 1 1 DBF zinc finger APG12 PF04110.13 EJP64666.1 - 5.6e-26 90.8 0.0 7.3e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Macoilin PF09726.9 EJP64666.1 - 0.0023 16.6 0.3 0.0028 16.3 0.3 1.0 1 0 0 1 1 1 1 Macoilin family Atg8 PF02991.16 EJP64666.1 - 0.0057 16.8 0.0 0.0085 16.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Myc_N PF01056.18 EJP64666.1 - 0.024 14.5 0.9 0.03 14.2 0.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 EJP64666.1 - 1.4 8.2 3.7 1.8 7.8 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EJP64666.1 - 1.5 9.2 5.9 2.5 8.5 5.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pantoate_transf PF02548.15 EJP64667.1 - 8.3e-107 356.4 0.6 1e-106 356.1 0.6 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EJP64667.1 - 9.5e-09 35.1 0.1 1.6e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase UQ_con PF00179.26 EJP64668.1 - 3.9e-35 120.6 0.0 4.9e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rap1_C PF11626.8 EJP64669.1 - 1.6e-22 79.4 0.7 4.3e-22 78.0 0.1 2.1 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EJP64669.1 - 1.5e-17 63.6 0.1 3.5e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 EJP64669.1 - 1.6e-08 34.9 0.0 3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain ARID PF01388.21 EJP64669.1 - 8.9e-06 26.3 0.0 5.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.10 EJP64669.1 - 0.00052 20.6 0.9 0.002 18.7 0.6 1.9 1 1 0 1 1 1 1 Rap1, DNA-binding DUF3235 PF11574.8 EJP64669.1 - 4.6 8.2 11.1 0.049 14.5 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) DHHC PF01529.20 EJP64670.1 - 2.3e-31 108.7 2.5 3.9e-31 107.9 2.5 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Aha1_N PF09229.11 EJP64671.1 - 6.8e-42 142.9 0.6 1e-41 142.3 0.6 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EJP64671.1 - 9.8e-18 64.6 0.9 1.7e-17 63.8 0.9 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Pyr_redox_3 PF13738.6 EJP64671.1 - 0.005 16.1 0.2 0.047 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SH3BGR PF04908.15 EJP64671.1 - 0.0064 16.6 1.6 2.7 8.2 0.1 3.8 3 2 2 5 5 5 1 SH3-binding, glutamic acid-rich protein Complex1_LYR_2 PF13233.6 EJP64673.1 - 3.9e-21 75.6 0.0 4.7e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Inositol_P PF00459.25 EJP64674.1 - 2.2e-48 165.1 2.0 4.3e-48 164.2 2.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 EJP64674.1 - 2.3e-11 44.2 0.1 4.1e-06 27.4 0.0 2.8 2 0 0 2 2 2 2 Ribosomal protein L6 Tubulin PF00091.25 EJP64675.1 - 4.5e-69 232.6 0.0 1.6e-68 230.8 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EJP64675.1 - 2.5e-42 144.0 0.1 4.2e-42 143.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EJP64675.1 - 2.9e-05 24.4 0.0 7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EJP64675.1 - 0.0049 16.6 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EJP64675.1 - 0.02 14.1 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Tubulin like ABC_tran PF00005.27 EJP64676.1 - 2.2e-47 161.0 0.0 1.2e-22 80.9 0.0 3.4 2 1 1 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EJP64676.1 - 8.2e-20 70.6 6.3 8.2e-20 70.6 6.3 3.5 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EJP64676.1 - 2.2e-17 63.8 4.7 0.00024 21.0 0.0 4.9 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP64676.1 - 3.9e-10 39.6 4.5 0.011 15.2 0.0 4.8 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EJP64676.1 - 4.6e-07 29.9 0.2 0.0069 16.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EJP64676.1 - 5.5e-07 30.2 0.1 0.036 14.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EJP64676.1 - 9.9e-07 29.4 11.5 0.018 15.6 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 EJP64676.1 - 5.6e-06 26.0 0.1 0.057 13.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP64676.1 - 6.7e-06 26.4 0.0 0.056 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EJP64676.1 - 1.7e-05 24.8 6.3 0.026 14.4 0.1 3.4 2 1 1 3 3 3 2 RsgA GTPase AAA PF00004.29 EJP64676.1 - 4.2e-05 24.0 0.2 0.55 10.7 0.1 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EJP64676.1 - 8.9e-05 22.3 2.6 0.0094 15.7 0.1 3.3 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 EJP64676.1 - 0.0001 22.7 2.3 0.079 13.3 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_14 PF13173.6 EJP64676.1 - 0.00014 21.9 0.5 2.1 8.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EJP64676.1 - 0.00018 21.7 0.4 0.46 10.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 EJP64676.1 - 0.00024 20.9 0.6 1 9.0 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EJP64676.1 - 0.00051 19.9 13.5 0.32 10.7 0.1 5.0 5 0 0 5 5 5 2 AAA ATPase domain MeaB PF03308.16 EJP64676.1 - 0.0012 17.9 3.0 0.11 11.4 0.0 2.6 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EJP64676.1 - 0.0019 18.5 4.6 0.13 12.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 EJP64676.1 - 0.0026 17.4 0.8 0.86 9.2 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 EJP64676.1 - 0.0042 16.7 1.9 4.4 6.9 0.0 3.6 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 EJP64676.1 - 0.0043 17.0 0.2 3.7 7.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 EJP64676.1 - 0.0049 17.1 0.2 0.88 9.8 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EJP64676.1 - 0.005 16.8 0.1 0.8 9.6 0.1 2.7 2 0 0 2 2 2 1 NTPase SRP54 PF00448.22 EJP64676.1 - 0.0058 16.3 1.0 0.8 9.3 0.0 3.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 EJP64676.1 - 0.0064 16.0 0.0 6.2 6.3 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EJP64676.1 - 0.0069 16.8 0.1 4.8 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 EJP64676.1 - 0.012 15.6 0.2 3.8 7.4 0.0 3.3 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_5 PF07728.14 EJP64676.1 - 0.012 15.6 0.3 3.2 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MobB PF03205.14 EJP64676.1 - 0.013 15.4 0.4 0.53 10.2 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 EJP64676.1 - 0.02 14.9 0.0 8.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EJP64676.1 - 0.026 15.0 2.4 9.8 6.6 0.0 3.8 3 0 0 3 3 3 0 AAA domain DUF2813 PF11398.8 EJP64676.1 - 0.031 13.6 0.1 2.1 7.5 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2813) NB-ARC PF00931.22 EJP64676.1 - 0.032 13.4 0.1 7.3 5.7 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 EJP64676.1 - 0.045 14.0 0.8 7.5 6.9 0.3 3.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EJP64676.1 - 0.055 12.7 1.5 4.5 6.5 0.1 3.2 3 0 0 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.25 EJP64676.1 - 0.067 12.8 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.18 EJP64676.1 - 0.13 11.8 0.7 3.6 7.1 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B dNK PF01712.19 EJP64676.1 - 0.42 10.4 4.1 26 4.6 0.2 3.3 3 0 0 3 3 3 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 EJP64676.1 - 0.44 10.3 2.0 31 4.2 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EJP64676.1 - 1.8 8.6 14.5 10 6.1 0.0 4.8 4 2 0 4 4 4 0 Dynamin family DUF87 PF01935.17 EJP64676.1 - 5.1 7.1 11.8 2.4 8.2 0.1 3.9 4 0 0 4 4 4 0 Helicase HerA, central domain Cyclin PF08613.11 EJP64677.1 - 0.14 12.5 0.1 0.77 10.1 0.1 2.2 1 0 0 1 1 1 0 Cyclin Pyridox_ox_2 PF12900.7 EJP64679.1 - 2.7e-35 121.4 0.0 3.9e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Spermine_synth PF01564.17 EJP64680.1 - 1.6e-06 27.7 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 EJP64680.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EJP64680.1 - 0.057 14.1 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EJP64680.1 - 0.061 14.0 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EJP64680.1 - 0.086 13.6 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 EJP64681.1 - 2.4e-19 69.4 0.1 4.1e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.20 EJP64682.1 - 3.8e-40 138.5 5.2 3.8e-40 138.5 5.2 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase zf-primase PF09329.11 EJP64683.1 - 1.1e-20 73.2 1.3 2e-20 72.3 1.3 1.5 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.10 EJP64684.1 - 3.1e-44 151.0 0.1 5.9e-44 150.1 0.1 1.5 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EJP64684.1 - 1.4e-22 79.8 0.0 3.7e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain DASH_Duo1 PF08651.10 EJP64685.1 - 4.9e-30 103.1 0.6 7.3e-30 102.6 0.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 CMV_US PF08001.11 EJP64685.1 - 0.05 12.9 0.7 0.074 12.3 0.7 1.2 1 0 0 1 1 1 0 CMV US DUF1682 PF07946.14 EJP64685.1 - 0.053 12.7 4.8 0.071 12.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) UPF0242 PF06785.11 EJP64685.1 - 0.056 13.6 3.1 0.07 13.2 3.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LTV PF04180.14 EJP64685.1 - 0.14 11.9 4.3 0.18 11.5 4.3 1.1 1 0 0 1 1 1 0 Low temperature viability protein DDHD PF02862.17 EJP64685.1 - 0.27 11.4 1.6 0.31 11.2 1.6 1.2 1 0 0 1 1 1 0 DDHD domain Rrn6 PF10214.9 EJP64685.1 - 0.28 9.7 10.5 0.29 9.6 10.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RAP1 PF07218.11 EJP64685.1 - 0.99 7.6 1.8 1.1 7.4 1.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hemopexin PF00045.19 EJP64686.1 - 0.0097 15.8 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 1 Hemopexin TTL PF03133.15 EJP64687.1 - 3.5e-55 187.2 0.0 5.5e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EJP64687.1 - 1.6e-54 184.7 0.2 3.2e-53 180.4 0.0 2.2 2 0 0 2 2 2 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EJP64687.1 - 0.00025 20.4 0.0 0.00061 19.1 0.0 1.5 2 0 0 2 2 2 1 YheC/D like ATP-grasp RRM_1 PF00076.22 EJP64688.1 - 2.1e-20 72.3 0.0 7.6e-11 41.7 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cation_ATPase_C PF00689.21 EJP64689.1 - 1.5e-43 148.6 6.0 1.5e-43 148.6 6.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EJP64689.1 - 5.6e-31 107.4 2.7 5.6e-31 107.4 2.7 3.4 4 1 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 EJP64689.1 - 3.1e-24 84.9 0.0 5.9e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EJP64689.1 - 2.4e-21 77.0 0.6 1.6e-20 74.3 0.6 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EJP64689.1 - 3.2e-07 29.9 0.2 3.8e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP64689.1 - 1.9e-06 27.8 0.3 2.2e-05 24.3 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP64689.1 - 0.083 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF202 PF02656.15 EJP64689.1 - 6 7.4 11.4 5.5 7.5 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF202) SIR2 PF02146.17 EJP64691.1 - 5e-57 192.7 0.0 7.1e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EJP64691.1 - 0.00052 19.8 0.1 0.54 10.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 EJP64691.1 - 0.059 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) DUF1451 PF07295.11 EJP64691.1 - 1.5 8.8 3.5 0.6 10.1 0.4 1.8 2 0 0 2 2 2 0 Zinc-ribbon containing domain FYDLN_acid PF09538.10 EJP64691.1 - 4.4 8.0 7.7 1.1 10.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Pkinase PF00069.25 EJP64692.1 - 1.6e-16 60.5 0.0 6.9e-16 58.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64692.1 - 3.3e-09 36.4 0.0 2.7e-08 33.4 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase DCB PF16213.5 EJP64692.1 - 0.0058 16.3 0.4 0.068 12.8 0.2 2.4 1 1 1 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Aminotran_4 PF01063.19 EJP64693.1 - 2.1e-35 122.6 0.0 2.6e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV ESSS PF10183.9 EJP64694.1 - 2.8e-10 40.3 0.1 3.6e-10 40.0 0.1 1.4 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FUSC_2 PF13515.6 EJP64695.1 - 2.4e-11 43.9 38.7 9e-09 35.5 6.1 3.3 2 1 1 3 3 3 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 EJP64695.1 - 2.5e-06 26.8 14.9 2.1e-05 23.7 4.1 3.0 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal DUF1097 PF06496.11 EJP64695.1 - 0.17 12.0 26.1 0.11 12.7 14.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) Dna2 PF08696.11 EJP64696.1 - 2.8e-71 239.6 0.1 9.8e-71 237.8 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 EJP64696.1 - 6.6e-51 172.8 0.0 1.1e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EJP64696.1 - 1.5e-35 123.3 0.5 7.1e-17 62.0 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EJP64696.1 - 2.5e-17 63.2 0.0 5.4e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP64696.1 - 1.2e-12 48.3 0.1 2.9e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 EJP64696.1 - 4.4e-10 39.9 0.0 6.8e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 EJP64696.1 - 3.2e-06 27.0 0.5 0.21 11.3 0.1 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EJP64696.1 - 8.2e-05 22.5 0.0 0.00025 20.9 0.0 1.9 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 EJP64696.1 - 9.7e-05 21.7 0.1 0.035 13.3 0.1 2.5 2 0 0 2 2 2 1 PIF1-like helicase AAA_25 PF13481.6 EJP64696.1 - 0.00057 19.5 0.3 0.18 11.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EJP64696.1 - 0.0011 19.4 0.0 0.0041 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 EJP64696.1 - 0.0019 17.9 0.2 0.004 16.8 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 EJP64696.1 - 0.0046 16.5 0.3 0.018 14.6 0.1 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region ResIII PF04851.15 EJP64696.1 - 0.0049 16.9 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MobB PF03205.14 EJP64696.1 - 0.005 16.7 0.2 0.014 15.3 0.2 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Csa1 PF06023.12 EJP64696.1 - 0.0098 15.3 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 CbiA PF01656.23 EJP64696.1 - 0.011 15.8 0.2 0.027 14.5 0.2 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD-helicase PF00580.21 EJP64696.1 - 0.013 15.1 0.1 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 EJP64696.1 - 0.014 14.7 0.0 0.038 13.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EJP64696.1 - 0.027 14.6 0.0 0.081 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EJP64696.1 - 0.035 14.1 0.1 0.088 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EJP64696.1 - 0.05 13.2 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EJP64696.1 - 0.086 12.8 0.3 0.21 11.5 0.3 1.6 1 0 0 1 1 1 0 NTPase RNA_pol_Rpc34 PF05158.12 EJP64696.1 - 0.092 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit AAA PF00004.29 EJP64696.1 - 0.1 13.1 0.1 0.29 11.5 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EJP64696.1 - 0.1 11.7 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 EJP64696.1 - 0.11 12.6 0.2 0.34 11.0 0.2 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain RuvB_N PF05496.12 EJP64696.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 EJP64696.1 - 0.12 11.3 0.0 0.29 10.1 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB p450 PF00067.22 EJP64697.1 - 1.7e-44 152.3 0.0 3.3e-44 151.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.6 EJP64698.1 - 3.3e-11 43.0 0.0 1.1e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EJP64698.1 - 8.1e-11 41.0 0.0 2.5e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EJP64698.1 - 1.1e-09 38.3 0.0 4.6e-08 33.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EJP64698.1 - 1.1e-08 34.6 0.0 9e-08 31.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EJP64698.1 - 2.9e-08 33.3 0.0 2.3e-06 27.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP64698.1 - 1.3e-06 27.9 0.0 0.0046 16.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EJP64698.1 - 1.9e-05 24.5 1.5 0.00013 21.6 0.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP64698.1 - 0.00012 21.3 0.5 0.013 14.6 0.1 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 EJP64698.1 - 0.00035 21.1 0.0 0.95 10.1 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EJP64698.1 - 0.00052 20.1 0.1 0.083 13.0 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 EJP64698.1 - 0.0025 17.2 0.9 0.044 13.1 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP64698.1 - 0.0026 16.9 0.1 0.0067 15.5 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EJP64698.1 - 0.0029 17.0 0.0 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EJP64698.1 - 0.0069 15.1 0.6 0.021 13.6 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Mqo PF06039.15 EJP64698.1 - 0.008 14.8 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 EJP64698.1 - 0.009 16.0 3.2 0.52 10.3 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 EJP64698.1 - 0.09 11.8 0.7 0.3 10.1 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A PQQ_3 PF13570.6 EJP64698.1 - 0.092 13.3 0.3 0.38 11.3 0.1 2.2 2 0 0 2 2 1 0 PQQ-like domain Aim21 PF11489.8 EJP64700.1 - 2e-164 549.4 76.0 2e-164 549.4 76.0 2.5 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Glyco_hydro_75 PF07335.11 EJP64701.1 - 4.7e-67 225.3 0.5 8.6e-67 224.5 0.5 1.4 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 5_nucleotid_C PF02872.18 EJP64702.1 - 2.4e-36 125.3 0.0 5.1e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EJP64702.1 - 1e-05 26.1 0.0 2.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase bZIP_1 PF00170.21 EJP64703.1 - 1.9e-06 27.9 5.0 3.2e-05 23.9 3.5 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EJP64703.1 - 6.8e-06 26.1 4.2 1.4e-05 25.1 4.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Fes1 PF08609.10 EJP64703.1 - 0.087 13.7 0.1 0.26 12.2 0.1 1.9 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 OPT PF03169.15 EJP64704.1 - 3.8e-166 554.3 50.2 4.4e-166 554.1 50.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 EJP64704.1 - 3.5 7.9 9.8 1 9.6 4.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) DCB PF16213.5 EJP64705.1 - 6.6e-45 152.9 6.3 3.7e-43 147.2 7.1 3.0 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EJP64705.1 - 1.2e-43 148.7 10.2 3.9e-42 143.8 0.1 4.3 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EJP64705.1 - 3.7e-28 98.2 8.2 1.9e-19 69.4 4.1 3.0 2 2 0 2 2 2 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 EJP64705.1 - 2e-05 24.3 1.3 0.0069 16.2 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DUF3636 PF12331.8 EJP64705.1 - 0.034 14.0 1.7 0.16 11.8 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) pP_pnuc_1 PF18165.1 EJP64705.1 - 0.051 13.5 0.1 0.47 10.3 0.0 2.5 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease IFRD PF05004.13 EJP64705.1 - 6.9 5.7 12.9 1.4 7.9 3.3 3.6 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) AA_permease PF00324.21 EJP64706.1 - 2.8e-92 309.8 32.8 3.6e-92 309.5 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP64706.1 - 8.9e-27 94.0 35.7 1.1e-26 93.7 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.11 EJP64706.1 - 0.046 14.0 0.2 0.046 14.0 0.2 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF1772) ABC_tran PF00005.27 EJP64707.1 - 2.4e-47 160.9 0.2 6.2e-24 85.1 0.0 3.7 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EJP64707.1 - 1.7e-25 88.8 2.4 4.4e-25 87.5 0.2 2.8 2 0 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 EJP64707.1 - 1.2e-18 68.0 0.0 0.0019 18.1 0.0 4.8 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP64707.1 - 2.3e-15 56.6 0.6 5.4e-05 22.7 0.1 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP64707.1 - 6.2e-11 43.2 0.1 0.00023 21.7 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJP64707.1 - 6.4e-09 35.4 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP64707.1 - 6.6e-08 32.6 0.1 0.00072 19.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EJP64707.1 - 2.4e-07 31.1 0.1 0.011 15.9 0.0 3.8 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 EJP64707.1 - 2.8e-07 30.6 0.0 0.0025 17.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EJP64707.1 - 6.5e-07 29.7 0.1 0.02 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EJP64707.1 - 5.3e-06 26.6 0.0 0.0019 18.2 0.0 3.0 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 EJP64707.1 - 1.1e-05 25.7 0.1 0.42 10.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EJP64707.1 - 1.1e-05 26.0 0.1 0.15 12.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 EJP64707.1 - 2.6e-05 24.7 0.0 0.65 10.4 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJP64707.1 - 3.8e-05 24.1 0.4 0.31 11.4 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain MeaB PF03308.16 EJP64707.1 - 5.5e-05 22.3 0.1 0.36 9.8 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 EJP64707.1 - 6.6e-05 22.7 0.1 0.075 12.8 0.0 3.1 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 EJP64707.1 - 6.8e-05 22.7 4.0 0.052 13.2 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain RNA_helicase PF00910.22 EJP64707.1 - 7.1e-05 23.2 0.0 0.79 10.1 0.0 3.0 2 0 0 2 2 2 2 RNA helicase HEAT PF02985.22 EJP64707.1 - 9.9e-05 22.3 1.1 2.2 8.8 0.1 4.3 4 0 0 4 4 3 1 HEAT repeat AAA_27 PF13514.6 EJP64707.1 - 0.0002 21.0 0.0 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EJP64707.1 - 0.00052 20.0 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 EJP64707.1 - 0.00066 18.9 0.6 0.34 10.1 0.0 3.8 4 0 0 4 4 4 1 NB-ARC domain AAA_24 PF13479.6 EJP64707.1 - 0.00081 19.2 0.3 1.5 8.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EJP64707.1 - 0.00083 19.4 0.0 3.4 7.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EJP64707.1 - 0.0013 18.5 0.0 3.3 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 EJP64707.1 - 0.0013 18.7 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain G-alpha PF00503.20 EJP64707.1 - 0.0014 17.9 0.2 1.7 7.7 0.0 2.8 3 0 0 3 3 3 2 G-protein alpha subunit DUF87 PF01935.17 EJP64707.1 - 0.0014 18.8 0.4 0.94 9.5 0.0 3.5 5 0 0 5 5 2 1 Helicase HerA, central domain cobW PF02492.19 EJP64707.1 - 0.0028 17.2 0.0 4.2 6.9 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 EJP64707.1 - 0.0042 17.3 0.0 1.7 8.9 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EJP64707.1 - 0.0048 17.1 0.0 6.8 6.9 0.0 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 EJP64707.1 - 0.0052 16.1 0.8 2 7.7 0.0 3.2 3 0 0 3 3 3 1 Septin AAA_13 PF13166.6 EJP64707.1 - 0.0083 14.8 0.7 2.5 6.6 0.0 3.5 4 0 0 4 4 3 1 AAA domain ATPase_2 PF01637.18 EJP64707.1 - 0.0092 15.9 0.0 3.2 7.6 0.0 3.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 EJP64707.1 - 0.0092 15.8 0.0 7.2 6.3 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EJP64707.1 - 0.013 15.3 0.0 0.79 9.5 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PRK PF00485.18 EJP64707.1 - 0.015 15.0 0.0 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 EJP64707.1 - 0.016 14.9 0.0 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 EJP64707.1 - 0.016 14.9 0.0 5.7 6.6 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EJP64707.1 - 0.017 14.6 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EJP64707.1 - 0.029 14.0 0.0 7.6 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EJP64707.1 - 0.048 12.7 0.1 3.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 EJP64707.1 - 0.055 13.2 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 EJP64707.1 - 0.058 13.3 0.0 16 5.4 0.0 2.8 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 EJP64707.1 - 0.059 12.7 0.0 12 5.2 0.0 2.9 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 EJP64707.1 - 0.061 12.7 0.0 4.3 6.7 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI CLASP_N PF12348.8 EJP64707.1 - 0.087 12.4 0.2 0.74 9.3 0.1 2.3 1 1 1 2 2 2 0 CLASP N terminal TsaE PF02367.17 EJP64707.1 - 0.093 12.7 0.2 42 4.2 0.0 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 EJP64707.1 - 0.095 12.6 0.1 20 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF815 PF05673.13 EJP64707.1 - 0.099 11.8 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Phage_lysozyme2 PF18013.1 EJP64707.1 - 0.11 12.6 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Phage tail lysozyme MukB PF04310.12 EJP64707.1 - 0.11 12.3 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal ParcG PF10274.9 EJP64707.1 - 0.12 12.4 0.5 4.2 7.5 0.0 2.8 1 1 1 3 3 3 0 Parkin co-regulated protein FeoB_N PF02421.18 EJP64707.1 - 0.15 11.6 0.1 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B HEAT_EZ PF13513.6 EJP64707.1 - 0.2 12.2 8.5 0.95 10.0 0.4 4.8 4 2 2 6 6 4 0 HEAT-like repeat DUF3367 PF11847.8 EJP64707.1 - 0.43 8.4 4.9 0.46 8.3 3.7 1.5 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase ATPase PF06745.13 EJP64707.1 - 1 8.6 5.4 7.5 5.8 0.7 3.2 3 0 0 3 3 3 0 KaiC DAP3 PF10236.9 EJP64707.1 - 2.3 7.3 4.5 22 4.1 0.5 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ICL PF00463.21 EJP64708.1 - 1.6e-195 650.6 0.6 1.9e-195 650.3 0.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Pil1 PF13805.6 EJP64708.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Eisosome component PIL1 DUF3439 PF11921.8 EJP64708.1 - 0.21 11.5 2.5 0.44 10.5 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) adh_short_C2 PF13561.6 EJP64709.1 - 9.3e-61 205.4 1.3 1.1e-60 205.2 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP64709.1 - 7.7e-43 146.2 0.1 9.7e-43 145.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP64709.1 - 9.8e-11 41.9 1.4 1.5e-10 41.2 1.4 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 EJP64709.1 - 1.1e-05 26.0 0.0 2.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 EJP64709.1 - 0.0001 22.2 0.2 0.00018 21.5 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 EJP64709.1 - 0.0011 19.7 0.0 0.0022 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.19 EJP64709.1 - 0.0051 16.1 0.5 0.012 14.9 0.5 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.14 EJP64709.1 - 0.013 15.1 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ChuX_HutX PF06228.13 EJP64709.1 - 0.027 14.3 0.1 7.2 6.4 0.0 2.4 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX RecC_C PF17946.1 EJP64709.1 - 0.03 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain Methyltransf_31 PF13847.6 EJP64709.1 - 0.034 13.9 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EJP64709.1 - 0.072 13.7 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.19 EJP64709.1 - 0.12 11.4 0.1 0.5 9.3 0.1 1.8 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family tRNA-synt_1c PF00749.21 EJP64710.1 - 1.9e-104 349.0 0.1 3.1e-104 348.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EJP64710.1 - 2.5e-31 108.9 0.0 7.1e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Sec7 PF01369.20 EJP64711.1 - 5.1e-70 234.9 0.3 5.1e-70 234.9 0.3 2.5 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 EJP64711.1 - 3e-40 137.7 2.1 3e-40 137.7 2.1 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EJP64711.1 - 2.2e-32 110.7 10.8 6.3e-32 109.3 0.1 5.3 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 EJP64711.1 - 6.9e-23 81.2 3.7 6.4e-22 78.1 0.3 3.1 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 RIH_assoc PF08454.11 EJP64711.1 - 0.21 11.5 2.0 0.93 9.4 0.1 3.2 3 1 0 3 3 3 0 RyR and IP3R Homology associated 2-oxoacid_dh PF00198.23 EJP64712.1 - 4.6e-76 255.3 0.1 6e-76 255.0 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EJP64712.1 - 5.2e-19 67.8 0.9 1.1e-18 66.8 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EJP64712.1 - 4e-13 49.5 0.5 1.2e-12 48.0 0.5 1.9 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 EJP64712.1 - 0.00081 19.9 0.7 0.0022 18.5 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3614) Calycin_like PF13944.6 EJP64712.1 - 0.14 12.5 1.0 2 8.7 0.0 2.6 1 1 0 2 2 2 0 Calycin-like beta-barrel domain Fungal_trans PF04082.18 EJP64713.1 - 8.7e-15 54.5 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64713.1 - 5.3e-09 36.0 9.7 1.2e-08 35.0 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1308 PF07000.11 EJP64715.1 - 3.3e-09 36.9 0.0 1.2e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) AAA PF00004.29 EJP64717.1 - 1.5e-15 57.8 0.0 4.8e-15 56.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EJP64717.1 - 0.015 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EJP64717.1 - 0.11 12.8 6.6 0.38 11.0 0.2 3.0 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 EJP64717.1 - 0.18 12.2 4.5 0.12 12.8 0.8 2.5 2 1 0 2 2 2 0 AAA ATPase domain PKD_channel PF08016.12 EJP64718.1 - 2.6e-05 23.1 19.6 0.00087 18.1 19.6 2.3 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EJP64718.1 - 9.4e-05 21.8 26.2 0.00058 19.2 26.2 2.0 1 1 0 1 1 1 1 Ion transport protein DUF2236 PF09995.9 EJP64718.1 - 1.7 8.8 4.0 9.3 6.4 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2236) Macro PF01661.21 EJP64719.1 - 1.4e-38 131.5 0.0 1.9e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Macro domain Amidohydro_1 PF01979.20 EJP64721.1 - 1.5e-17 64.0 0.0 4.2e-17 62.5 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EJP64721.1 - 2e-08 34.2 0.1 6.1e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Nuc_deoxyri_tr2 PF15891.5 EJP64722.1 - 1.1e-36 125.4 0.0 1.5e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Peptidase_S8 PF00082.22 EJP64723.1 - 6.4e-37 127.4 0.9 1.1e-36 126.7 0.9 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EJP64723.1 - 1.6e-10 41.7 0.0 3.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 EJP64723.1 - 0.065 13.1 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 FlgD Ig-like domain RNA_pol_3_Rpc31 PF11705.8 EJP64724.1 - 1.8e-64 218.1 1.3 2e-64 217.9 1.3 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Nucleoporin_FG PF13634.6 EJP64725.1 - 9.9e-22 77.6 139.8 3.1e-09 37.5 26.3 4.4 2 1 3 5 5 5 4 Nucleoporin FG repeat region Baculo_PEP_C PF04513.12 EJP64725.1 - 0.017 15.2 0.6 1.4 8.9 0.6 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EJP64725.1 - 0.056 12.3 0.1 8.2 5.2 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Vps53_N PF04100.12 EJP64725.1 - 0.11 11.5 0.9 0.19 10.7 0.9 1.3 1 0 0 1 1 1 0 Vps53-like, N-terminal RmuC PF02646.16 EJP64725.1 - 0.16 11.1 1.1 3.6 6.6 0.0 2.6 2 1 1 3 3 3 0 RmuC family Fzo_mitofusin PF04799.13 EJP64725.1 - 0.19 11.3 0.2 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 fzo-like conserved region Tup_N PF08581.10 EJP64725.1 - 0.2 12.0 2.5 0.37 11.1 0.7 2.2 2 0 0 2 2 2 0 Tup N-terminal ISG65-75 PF11727.8 EJP64725.1 - 0.2 10.8 0.2 1 8.5 0.0 2.1 2 1 0 2 2 2 0 Invariant surface glycoprotein DUF1664 PF07889.12 EJP64725.1 - 0.62 10.1 2.6 2.8 8.0 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FliJ PF02050.16 EJP64725.1 - 1.1 9.5 5.0 17 5.7 0.4 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein zf-C4H2 PF10146.9 EJP64725.1 - 1.9 8.8 4.4 1.4 9.2 0.2 2.6 3 0 0 3 3 3 0 Zinc finger-containing protein Flagellin_C PF00700.21 EJP64725.1 - 4.7 7.6 6.4 12 6.3 0.0 3.5 3 1 1 4 4 4 0 Bacterial flagellin C-terminal helical region Fip1 PF05182.13 EJP64726.1 - 1.6e-20 72.4 1.2 2.9e-20 71.5 1.2 1.5 1 0 0 1 1 1 1 Fip1 motif Neprosin PF03080.15 EJP64727.1 - 3.3e-51 173.8 3.2 4.2e-51 173.4 3.2 1.1 1 0 0 1 1 1 1 Neprosin Glyco_hydro_18 PF00704.28 EJP64728.1 - 1.5e-20 74.2 2.7 1.6e-19 70.8 2.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 EJP64728.1 - 2.3e-11 43.4 8.3 1e-10 41.4 8.3 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Med3 PF11593.8 EJP64728.1 - 5.9 6.0 8.3 0.13 11.4 0.6 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Peptidase_M50B PF13398.6 EJP64729.1 - 3.6e-60 203.0 19.4 4.4e-60 202.7 19.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 EJP64729.1 - 0.0081 15.5 0.2 0.019 14.2 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M50 YlaC PF10777.9 EJP64729.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.1 2 0 0 2 2 2 0 Inner membrane protein YlaC Peptidase_M41 PF01434.18 EJP64729.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M41 MLANA PF14991.6 EJP64729.1 - 0.49 10.7 5.4 0.3 11.4 0.4 2.4 1 1 1 2 2 2 0 Protein melan-A TMEM208_SND2 PF05620.11 EJP64729.1 - 2.7 7.8 6.1 9.7 5.9 0.0 2.6 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Chitin_bind_1 PF00187.19 EJP64730.1 - 9.1e-07 29.3 16.0 1.5e-06 28.6 14.7 1.8 2 0 0 2 2 2 1 Chitin recognition protein Pkinase PF00069.25 EJP64731.1 - 4.3e-14 52.5 0.0 1.2e-13 51.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain CMAS PF02353.20 EJP64734.1 - 1.4e-38 132.7 0.2 1.9e-38 132.4 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EJP64734.1 - 7.5e-18 65.0 0.0 1.3e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP64734.1 - 1.2e-17 64.4 0.0 2.1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP64734.1 - 5.7e-16 58.7 0.0 7.7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP64734.1 - 1e-13 51.5 0.0 1.6e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP64734.1 - 6.8e-13 49.2 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP64734.1 - 1.6e-09 37.6 0.0 3.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EJP64734.1 - 5.1e-07 29.3 0.0 7.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 EJP64734.1 - 2.8e-05 24.0 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltr_RsmB-F PF01189.17 EJP64734.1 - 4.9e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TehB PF03848.14 EJP64734.1 - 7.6e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 EJP64734.1 - 0.00019 21.0 0.0 0.0012 18.4 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 EJP64734.1 - 0.0012 18.6 0.1 0.0033 17.2 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EJP64734.1 - 0.0037 16.6 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 EJP64734.1 - 0.0051 15.9 0.0 0.0096 15.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 EJP64734.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 EJP64734.1 - 0.068 13.3 0.1 0.62 10.1 0.0 2.2 2 1 0 2 2 1 0 FtsJ-like methyltransferase Lipocalin_2 PF08212.12 EJP64735.1 - 7.2e-20 71.4 0.0 8.5e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 EJP64735.1 - 4.1e-06 27.1 0.0 7e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF5546 PF17700.1 EJP64735.1 - 0.04 14.3 0.0 0.055 13.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5546) Abp2 PF09441.10 EJP64735.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 ARS binding protein 2 p450 PF00067.22 EJP64736.1 - 4.2e-57 193.9 0.0 5.2e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DPM3 PF08285.11 EJP64736.1 - 0.096 12.9 2.0 17 5.7 0.0 2.9 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MFS_1 PF07690.16 EJP64737.1 - 8.7e-22 77.5 28.9 8.7e-22 77.5 28.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EJP64737.1 - 0.011 14.0 0.1 0.028 12.7 0.1 1.7 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family BTP PF05232.12 EJP64737.1 - 0.015 15.4 15.1 0.93 9.6 3.8 4.3 3 2 0 3 3 3 0 Chlorhexidine efflux transporter PCI PF01399.27 EJP64738.1 - 2.8e-19 69.6 0.5 1.6e-18 67.1 0.1 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 EJP64738.1 - 0.028 14.5 4.0 0.12 12.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CARD PF00619.21 EJP64738.1 - 0.089 12.8 0.1 0.77 9.8 0.0 2.6 2 1 0 2 2 2 0 Caspase recruitment domain PriX PF18689.1 EJP64738.1 - 0.093 13.1 1.6 1.7 9.1 0.3 2.8 2 0 0 2 2 2 0 Primase X TPR_7 PF13176.6 EJP64738.1 - 0.16 12.1 0.3 4 7.7 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EJP64738.1 - 0.65 9.9 3.3 4.9 7.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C65 PF10275.9 EJP64739.1 - 4.6e-53 180.2 0.0 6e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Gln-synt_C PF00120.24 EJP64740.1 - 6.7e-82 275.2 0.0 7.9e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Citrate_synt PF00285.21 EJP64741.1 - 3.4e-99 332.3 0.0 4.2e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Anoctamin PF04547.12 EJP64742.1 - 7.6e-106 354.6 8.0 9e-106 354.4 8.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel MHYT PF03707.16 EJP64743.1 - 1.8e-17 63.2 23.9 3.9e-10 39.8 0.2 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat YfhO PF09586.10 EJP64743.1 - 0.36 9.0 4.1 0.54 8.4 4.1 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO AMP-binding PF00501.28 EJP64744.1 - 1.5e-85 287.3 0.0 1.9e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PsiB PF06290.11 EJP64744.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) ArabFuran-catal PF09206.11 EJP64745.1 - 3.7e-133 443.7 7.0 4.7e-133 443.4 7.0 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 EJP64745.1 - 3.7e-53 179.3 0.8 6.2e-53 178.5 0.8 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Fungal_trans PF04082.18 EJP64746.1 - 3.2e-08 32.9 1.5 1.3e-07 30.9 1.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64746.1 - 1.8e-07 31.1 13.8 5.2e-07 29.7 13.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 EJP64747.1 - 4.9e-38 131.0 0.1 6.9e-38 130.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP64747.1 - 2e-11 44.3 0.1 9.8e-09 35.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP64747.1 - 3.2e-05 24.0 1.1 0.45 10.5 0.0 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 EJP64747.1 - 0.00025 20.8 8.1 1.6 8.3 0.1 3.6 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP64747.1 - 0.0089 16.2 0.6 1.7 8.9 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EJP64747.1 - 0.025 13.6 0.6 2.3 7.1 0.5 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EJP64747.1 - 0.054 12.7 0.0 0.64 9.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP64747.1 - 0.065 12.3 1.9 0.94 8.5 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EJP64747.1 - 0.29 10.3 4.9 12 5.0 0.6 3.2 2 1 0 3 3 3 0 FAD binding domain Glyco_hydro_18 PF00704.28 EJP64748.1 - 1.1e-22 81.2 1.3 1.1e-20 74.7 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Staphostatin_A PF09022.10 EJP64750.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Staphostatin A SAYSvFN PF10260.9 EJP64750.1 - 4.1 7.4 4.8 3 7.8 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) OmdA PF13376.6 EJP64751.1 - 1.3e-17 63.6 6.7 1.4e-17 63.5 1.6 2.4 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated TOM6p PF15184.6 EJP64751.1 - 0.11 12.3 0.4 0.98 9.2 0.0 2.3 1 1 1 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog Pyr_redox_2 PF07992.14 EJP64752.1 - 5.3e-49 167.0 0.9 7.7e-49 166.5 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EJP64752.1 - 9.5e-15 54.3 0.0 2.2e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EJP64752.1 - 6.1e-14 52.4 2.2 4.5e-12 46.4 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EJP64752.1 - 2.9e-06 27.7 0.0 8.4e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 EJP64752.1 - 0.0018 17.5 0.2 0.42 9.7 0.1 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EJP64752.1 - 0.032 14.7 1.0 0.83 10.1 0.0 2.4 1 1 1 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EJP64752.1 - 0.038 14.0 0.5 14 5.6 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF1188 PF06690.11 EJP64752.1 - 0.065 12.8 0.1 0.097 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Tropomyosin PF00261.20 EJP64753.1 - 0.012 15.0 17.5 0.012 15.0 5.4 2.8 1 1 1 2 2 2 0 Tropomyosin Fib_alpha PF08702.10 EJP64753.1 - 1.7 8.8 9.5 1.6 8.9 0.2 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family TolA_bind_tri PF16331.5 EJP64753.1 - 2.7 8.1 23.2 2.5 8.2 11.1 3.9 3 1 0 3 3 3 0 TolA binding protein trimerisation V_ATPase_I PF01496.19 EJP64753.1 - 3.8 5.3 4.8 5.3 4.8 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Efg1 PF10153.9 EJP64753.1 - 3.8 7.9 8.9 11 6.4 8.9 1.8 1 0 0 1 1 1 0 rRNA-processing protein Efg1 Phage_GP20 PF06810.11 EJP64753.1 - 4.5 7.1 14.6 0.33 10.7 4.8 2.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 DivIVA PF05103.13 EJP64753.1 - 6.6 6.8 19.0 2.6 8.2 0.1 2.9 2 1 0 2 2 2 0 DivIVA protein Rft-1 PF04506.13 EJP64754.1 - 1.8e-141 472.4 8.6 2.1e-141 472.2 8.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 EJP64754.1 - 0.00067 19.1 5.4 0.00067 19.1 5.4 3.5 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 EJP64754.1 - 0.0039 16.5 4.1 0.0039 16.5 4.1 3.7 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein DUF2160 PF09928.9 EJP64754.1 - 0.48 10.8 4.9 6.3 7.2 0.6 3.2 3 0 0 3 3 3 0 Predicted small integral membrane protein (DUF2160) DEAD PF00270.29 EJP64755.1 - 3.8e-50 170.1 0.0 1.3e-49 168.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP64755.1 - 2.1e-33 115.0 0.0 1.1e-29 102.9 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain UTP25 PF06862.12 EJP64755.1 - 0.00087 18.2 0.1 0.0057 15.5 0.0 2.2 2 1 0 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SRP1_TIP1 PF00660.17 EJP64755.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Seripauperin and TIP1 family Pkinase_fungal PF17667.1 EJP64755.1 - 0.1 11.3 4.2 0.14 10.9 4.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF3807 PF12720.7 EJP64755.1 - 6 7.1 30.9 13 6.0 30.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) HORMA PF02301.18 EJP64756.1 - 1.9e-33 115.8 0.0 2.2e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EJP64756.1 - 0.00092 19.2 0.2 0.0041 17.1 0.2 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 Ribosomal_60s PF00428.19 EJP64756.1 - 0.0039 17.8 4.0 0.0068 17.0 4.0 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2660 PF10859.8 EJP64756.1 - 0.01 16.3 0.0 0.076 13.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) UCH PF00443.29 EJP64757.1 - 2e-34 119.3 0.0 2.8e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EJP64757.1 - 2.1e-22 78.6 2.5 1.4e-21 76.0 0.1 2.8 3 0 0 3 3 3 1 Variant UBP zinc finger UBA PF00627.31 EJP64757.1 - 1.3e-20 72.9 0.1 1.2e-11 44.3 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 EJP64757.1 - 4.9e-20 71.6 12.9 3.7e-19 68.8 1.7 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EJP64757.1 - 1e-13 51.6 0.0 1.9e-12 47.4 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CTU2 PF10288.9 EJP64757.1 - 0.027 14.7 0.3 0.096 12.9 0.3 1.9 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Methyltransf_25 PF13649.6 EJP64758.1 - 6.2e-16 58.9 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP64758.1 - 3.2e-11 43.7 0.0 5.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP64758.1 - 4e-10 39.7 0.0 6.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP64758.1 - 1.1e-09 38.9 0.0 2.3e-09 37.9 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP64758.1 - 1.2e-07 31.8 0.0 1.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP64758.1 - 1.3e-07 31.2 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EJP64758.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EJP64758.1 - 0.00043 20.4 0.0 0.00052 20.2 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EJP64758.1 - 0.0036 16.7 0.0 0.0047 16.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 EJP64758.1 - 0.0042 16.1 0.0 0.0056 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 EJP64758.1 - 0.0052 16.4 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 EJP64758.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_5 PF01795.19 EJP64758.1 - 0.29 10.6 0.0 0.4 10.1 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Methyltransf_25 PF13649.6 EJP64759.1 - 9.5e-10 39.1 0.0 1.7e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP64759.1 - 4.1e-08 33.2 0.0 5.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP64759.1 - 1.3e-07 32.1 0.0 2.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP64759.1 - 6.8e-07 30.0 0.0 1.4e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP64759.1 - 0.00017 21.5 0.0 0.00025 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP64759.1 - 0.00033 20.1 0.0 0.00043 19.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EJP64759.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.11 EJP64759.1 - 0.046 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) NifU_N PF01592.16 EJP64760.1 - 6.4e-55 184.8 0.9 1.2e-53 180.6 0.0 2.0 2 0 0 2 2 2 1 NifU-like N terminal domain bMG5 PF17972.1 EJP64760.1 - 0.061 13.7 0.0 0.091 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain ArAE_2_N PF10337.9 EJP64761.1 - 2.2e-19 69.9 10.4 7.7e-18 64.8 0.8 3.4 3 1 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EJP64761.1 - 6.4e-10 39.2 18.5 6.4e-10 39.2 18.5 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EJP64761.1 - 9.4e-07 28.9 0.0 3.5e-05 23.8 0.0 2.4 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EJP64761.1 - 0.049 12.5 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter KRTDAP PF15200.6 EJP64761.1 - 0.1 12.4 0.0 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 Keratinocyte differentiation-associated Beta-lactamase PF00144.24 EJP64762.1 - 6.5e-40 137.4 0.2 1.1e-39 136.6 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase G_glu_transpept PF01019.21 EJP64763.1 - 8.7e-160 532.9 0.5 9.9e-160 532.7 0.5 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Phospholip_A2_3 PF09056.11 EJP64764.1 - 2.4e-40 137.6 0.7 2.4e-40 137.6 0.7 1.4 2 0 0 2 2 2 1 Prokaryotic phospholipase A2 Cupin_2 PF07883.11 EJP64765.1 - 1.4e-09 37.6 0.1 9.2e-09 34.9 0.0 2.0 1 1 1 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EJP64765.1 - 1.3e-05 24.8 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EJP64765.1 - 0.0082 15.8 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 Cupin cNMP_binding PF00027.29 EJP64765.1 - 0.09 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Aldedh PF00171.22 EJP64766.1 - 2.2e-151 504.5 0.1 2.5e-151 504.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sugar_tr PF00083.24 EJP64767.1 - 8e-125 417.2 29.6 9.2e-125 417.0 29.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP64767.1 - 3.4e-21 75.6 33.3 3.4e-21 75.6 33.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0242 PF06785.11 EJP64767.1 - 0.18 11.9 1.0 7.7 6.6 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Aa_trans PF01490.18 EJP64768.1 - 1.7e-52 178.5 32.1 1.9e-52 178.4 32.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2156 PF09924.9 EJP64769.1 - 3.2e-25 88.8 0.0 5.4e-25 88.0 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) MFS_1 PF07690.16 EJP64770.1 - 3.6e-36 124.8 90.0 1.1e-25 90.3 44.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy_2 PF13532.6 EJP64771.1 - 1e-13 51.9 0.0 1.6e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CFEM PF05730.11 EJP64772.1 - 1.5e-09 37.8 17.3 1.5e-09 37.8 17.3 1.7 2 0 0 2 2 2 1 CFEM domain Cation_ATPase_C PF00689.21 EJP64772.1 - 0.0095 15.7 6.7 0.76 9.5 0.4 2.2 1 1 0 2 2 2 2 Cation transporting ATPase, C-terminus Glyco_transf_28 PF03033.20 EJP64773.1 - 1.2e-16 61.0 0.0 3e-15 56.5 0.0 2.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EJP64773.1 - 1.8e-07 30.3 0.1 2.9e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EJP64773.1 - 0.00027 21.0 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF2985 PF11204.8 EJP64774.1 - 1.1e-37 128.0 0.3 1.1e-37 128.0 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) SelP_N PF04592.14 EJP64774.1 - 0.19 11.1 7.6 0.29 10.5 7.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MFS_1 PF07690.16 EJP64775.1 - 1e-30 106.9 51.6 1e-30 106.9 51.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.11 EJP64775.1 - 1.9 7.9 4.5 2 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PEP_mutase PF13714.6 EJP64777.1 - 7.3e-42 143.5 0.1 8.7e-42 143.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EJP64777.1 - 9.9e-19 67.2 0.0 1.4e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.11 EJP64778.1 - 2.8e-47 161.1 13.5 3.6e-47 160.8 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2635 PF10948.8 EJP64778.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) FA_hydroxylase PF04116.13 EJP64779.1 - 5.6e-22 78.5 10.8 5.6e-22 78.5 10.8 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ADH_zinc_N PF00107.26 EJP64780.1 - 3.8e-22 78.7 0.2 9.6e-22 77.4 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP64780.1 - 9.1e-20 70.6 2.5 2.3e-19 69.3 2.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EJP64780.1 - 0.00093 20.3 0.0 0.0033 18.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PALP PF00291.25 EJP64780.1 - 0.0015 18.1 0.6 0.0022 17.5 0.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glu_dehyd_C PF16912.5 EJP64780.1 - 0.0045 16.5 0.1 0.0066 16.0 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EJP64780.1 - 0.013 14.9 3.6 0.02 14.2 3.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EJP64780.1 - 0.043 14.1 0.1 0.18 12.1 0.2 1.8 2 1 0 2 2 2 0 TrkA-N domain adh_short PF00106.25 EJP64780.1 - 0.045 13.2 0.4 0.98 8.8 0.4 2.4 2 0 0 2 2 2 0 short chain dehydrogenase Fungal_trans PF04082.18 EJP64781.1 - 5.5e-24 84.6 0.2 8.5e-24 84.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64781.1 - 3.6e-11 43.0 7.4 6.7e-11 42.1 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.27 EJP64782.1 - 0.017 15.1 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Glyco_hydro_76 PF03663.14 EJP64783.1 - 4e-121 405.0 12.5 1.4e-61 209.1 0.6 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 p450 PF00067.22 EJP64784.1 - 6.6e-18 64.7 0.0 9.2e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 EJP64786.1 - 4.7e-10 39.7 0.0 6.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP64786.1 - 7.3e-07 29.2 0.0 1.3e-06 28.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP64786.1 - 0.00075 19.9 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RGS PF00615.19 EJP64787.1 - 3e-05 24.3 0.1 9.8e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain MFS_1 PF07690.16 EJP64788.1 - 2e-23 82.9 79.2 5.3e-17 61.8 43.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EJP64788.1 - 0.00043 19.7 19.7 0.00043 19.7 19.7 1.6 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB LapA_dom PF06305.11 EJP64788.1 - 0.05 13.4 2.3 0.14 12.0 0.3 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SurE PF01975.17 EJP64789.1 - 4.7e-41 140.7 0.0 6.2e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE DUF1833 PF08875.11 EJP64789.1 - 0.19 11.2 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1833) MaoC_dehydrat_N PF13452.6 EJP64790.1 - 0.00023 21.3 0.0 0.00097 19.3 0.0 2.0 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase ATP-grasp_2 PF08442.10 EJP64791.1 - 4.9e-25 88.3 0.0 8.9e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EJP64791.1 - 1.5e-18 67.1 2.1 2.9e-18 66.1 2.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EJP64791.1 - 0.0059 16.1 0.7 0.03 13.8 0.1 2.0 2 1 0 3 3 3 1 ATP-grasp domain DLH PF01738.18 EJP64792.1 - 4.1e-17 62.5 0.0 1.5e-16 60.6 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family TLP1_add_C PF18313.1 EJP64793.1 - 6.1e-21 74.2 0.0 1.9e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain ECH_1 PF00378.20 EJP64794.1 - 4.8e-50 170.2 0.0 6.3e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP64794.1 - 5e-24 85.4 0.7 9.2e-23 81.2 0.7 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase UPF0444 PF15475.6 EJP64794.1 - 0.0045 17.2 0.6 0.0075 16.5 0.6 1.4 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Peptidase_S49 PF01343.18 EJP64794.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 Mac PF12464.8 EJP64796.1 - 1.3e-15 57.4 0.0 2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 EJP64796.1 - 5.2e-13 48.1 14.6 5.2e-11 41.8 4.6 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EJP64796.1 - 1.4e-11 43.9 3.9 1.4e-11 43.9 3.9 3.3 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.16 EJP64797.1 - 3.1e-25 88.8 54.1 3.2e-18 65.8 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tim17 PF02466.19 EJP64797.1 - 0.75 10.2 5.7 0.07 13.5 0.7 2.0 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family CoA_binding PF02629.19 EJP64798.1 - 8.6e-22 77.6 1.3 8.6e-22 77.6 1.3 2.1 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EJP64798.1 - 1.8e-15 57.1 0.4 3.5e-15 56.1 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EJP64798.1 - 8.8e-09 35.3 0.1 1.6e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Chromo PF00385.24 EJP64800.1 - 3.6e-11 42.8 2.4 2.1e-07 30.8 0.1 2.5 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain YlbD_coat PF14071.6 EJP64800.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative coat protein DUF4112 PF13430.6 EJP64801.1 - 2e-31 108.4 0.5 2.8e-31 107.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ribonuc_red_sm PF00268.21 EJP64802.1 - 7.1e-120 399.7 2.5 8.5e-120 399.4 2.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Pkinase PF00069.25 EJP64803.1 - 1.3e-60 205.1 0.0 1.7e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SRP9-21 PF05486.12 EJP64803.1 - 1.1e-32 112.3 0.3 1.1e-32 112.3 0.3 2.8 3 1 0 3 3 3 1 Signal recognition particle 9 kDa protein (SRP9) Pkinase_Tyr PF07714.17 EJP64803.1 - 1.5e-27 96.5 0.0 3.1e-27 95.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP64803.1 - 0.0049 16.2 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJP64803.1 - 0.0076 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP64803.1 - 0.12 12.3 0.0 0.12 12.3 0.0 3.1 5 0 0 5 5 5 0 Phosphotransferase enzyme family Methyltransf_28 PF02636.17 EJP64804.1 - 1.1e-81 274.3 0.0 1.4e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lung_7-TM_R PF06814.13 EJP64805.1 - 3.1e-69 233.5 18.1 3.7e-69 233.2 18.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Pro_isomerase PF00160.21 EJP64806.1 - 1.9e-49 168.0 0.0 4.3e-49 166.8 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EJP64806.1 - 1.6e-05 24.9 0.5 0.00055 20.0 0.0 3.0 4 0 0 4 4 4 1 U-box domain zf-NOSIP PF15906.5 EJP64806.1 - 0.00019 21.5 0.0 0.00042 20.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein RasGEF PF00617.19 EJP64808.1 - 7.6e-60 202.1 0.2 1.8e-59 200.9 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EJP64808.1 - 2.5e-27 95.2 0.7 6.3e-27 93.9 0.7 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EJP64808.1 - 1.7e-15 56.3 0.1 3.5e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP64808.1 - 3.9e-14 52.2 0.2 8.1e-14 51.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJP64808.1 - 2.3e-13 49.6 0.1 5.3e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EJP64808.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 WW domain HAUS4 PF14735.6 EJP64808.1 - 0.12 12.0 1.1 0.29 10.8 1.1 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Fungal_trans PF04082.18 EJP64809.1 - 2.7e-15 56.1 1.8 4.9e-15 55.3 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EJP64809.1 - 4.6e-08 33.1 12.2 1.1e-05 25.6 5.8 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EJP64809.1 - 0.00077 19.8 14.6 0.04 14.4 5.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EJP64809.1 - 0.03 15.0 0.9 4 8.1 0.1 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 EJP64809.1 - 0.21 12.5 19.5 0.27 12.2 4.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP64809.1 - 0.36 11.2 6.8 1.4 9.3 3.7 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 EJP64809.1 - 1.5 9.0 4.1 4.1 7.6 4.1 1.8 1 0 0 1 1 1 0 Zinc ribbon domain Glyco_hydro_16 PF00722.21 EJP64810.1 - 9.6e-10 38.2 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_64 PF16483.5 EJP64811.1 - 6.5e-134 446.9 0.0 7.2e-134 446.7 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Zn_clus PF00172.18 EJP64812.1 - 4.9e-09 36.2 11.0 1.4e-08 34.7 11.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP64812.1 - 1.4e-07 30.7 0.4 2.7e-05 23.2 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain Rep_fac-A_C PF08646.10 EJP64812.1 - 0.11 12.3 3.6 0.26 11.0 3.6 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain POB3_N PF17292.2 EJP64814.1 - 9e-32 109.4 0.5 1.4e-30 105.6 0.2 2.4 2 0 0 2 2 2 1 POB3-like N-terminal PH domain SSrecog PF03531.14 EJP64814.1 - 2.4e-28 97.8 0.2 1.2e-27 95.6 0.0 2.4 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EJP64814.1 - 1.8e-22 79.6 0.0 8.8e-22 77.3 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PBD PF00786.28 EJP64815.1 - 0.00017 21.9 0.0 0.0012 19.2 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Mg_trans_NIPA PF05653.14 EJP64816.1 - 3.1e-45 154.6 14.9 3.8e-23 82.0 1.7 3.1 2 1 1 3 3 3 3 Magnesium transporter NIPA EamA PF00892.20 EJP64816.1 - 0.0031 17.7 0.1 0.0031 17.7 0.1 4.2 4 1 1 5 5 5 2 EamA-like transporter family DUF4131 PF13567.6 EJP64816.1 - 0.056 13.1 2.5 2.8 7.6 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) KbaA PF14089.6 EJP64816.1 - 0.37 10.6 4.9 0.68 9.8 4.9 1.4 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation LysE PF01810.18 EJP64816.1 - 0.82 9.1 12.7 0.017 14.6 2.4 3.1 3 1 1 4 4 4 0 LysE type translocator HlyIII PF03006.20 EJP64816.1 - 0.94 9.1 7.0 4.2 7.0 5.5 2.2 2 1 0 2 2 2 0 Haemolysin-III related DUF1461 PF07314.11 EJP64816.1 - 2.1 8.2 5.1 0.89 9.4 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF2569 PF10754.9 EJP64816.1 - 6.3 7.2 9.7 0.79 10.2 4.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) aGPT-Pplase2 PF18724.1 EJP64817.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 RRM_1 PF00076.22 EJP64818.1 - 4.2e-56 186.7 0.5 4.4e-16 58.4 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EJP64818.1 - 1.4e-08 35.2 2.0 0.55 10.5 0.0 6.2 4 3 2 6 6 6 3 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 EJP64818.1 - 2.5e-06 27.4 0.1 0.0013 18.6 0.0 2.8 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EJP64818.1 - 6.3e-05 23.0 0.0 2 8.6 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 EJP64818.1 - 0.043 13.4 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.10 EJP64818.1 - 1.2 8.4 38.7 0.5 9.6 25.6 2.5 2 0 0 2 2 2 0 BUD22 Cnd3 PF12719.7 EJP64819.1 - 2.3e-90 302.8 3.6 2.3e-90 302.7 0.9 2.3 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EJP64819.1 - 1.5e-10 41.4 15.8 3.3e-06 27.4 2.2 4.8 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 EJP64819.1 - 1.3e-06 28.1 14.0 0.14 12.5 0.0 7.4 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 EJP64819.1 - 0.00073 19.6 11.4 0.31 11.1 0.1 5.1 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 FANCI_HD1 PF14679.6 EJP64819.1 - 0.0013 18.6 0.4 0.059 13.3 0.0 2.8 2 0 0 2 2 2 1 FANCI helical domain 1 RTP1_C1 PF10363.9 EJP64819.1 - 0.072 13.3 0.7 2.5 8.3 0.1 3.3 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 U3snoRNP10 PF12397.8 EJP64819.1 - 0.097 13.0 0.3 0.82 10.0 0.1 2.6 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 EJP64819.1 - 0.11 13.0 12.5 8.8 6.9 0.6 5.7 5 1 1 6 6 6 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EJP64819.1 - 0.12 13.0 0.1 1.9 9.2 0.0 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EJP64819.1 - 0.72 8.9 6.9 0.19 10.8 0.0 3.3 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) Phosphodiest PF01663.22 EJP64820.1 - 9.5e-14 51.7 2.5 4.2e-10 39.8 0.4 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EJP64820.1 - 0.00012 21.7 0.0 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 EJP64820.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF2423 PF10338.9 EJP64821.1 - 9.6e-19 67.3 2.9 9.6e-19 67.3 2.9 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) PINIT PF14324.6 EJP64822.1 - 8.1e-39 133.3 0.0 2e-38 132.0 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EJP64822.1 - 1.1e-22 79.5 4.9 1.8e-22 78.8 4.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EJP64822.1 - 3.6e-05 23.5 0.7 6.9e-05 22.6 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 EJP64822.1 - 4.9e-05 23.0 0.0 9.7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 EJP64822.1 - 0.039 14.0 0.7 0.13 12.3 0.4 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_5 PF14634.6 EJP64822.1 - 0.44 10.6 3.3 0.86 9.6 3.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EJP64822.1 - 0.47 10.6 5.1 0.91 9.7 5.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EJP64822.1 - 0.95 9.9 4.3 2 8.8 4.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EJP64822.1 - 2.7 7.9 5.0 5.8 6.9 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TRAPP PF04051.16 EJP64823.1 - 2.8e-45 153.6 0.0 5.3e-45 152.7 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_C PF02866.18 EJP64824.1 - 8.1e-46 156.0 0.0 1.2e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EJP64824.1 - 1.5e-43 148.3 0.2 2.1e-43 147.8 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EJP64824.1 - 0.017 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L28e PF01778.17 EJP64825.1 - 3.4e-35 121.3 0.9 3.4e-35 121.3 0.9 1.5 1 1 1 2 2 2 1 Ribosomal L28e protein family DUF2015 PF09435.10 EJP64826.1 - 3.8e-47 158.8 0.0 4.4e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) WD40 PF00400.32 EJP64827.1 - 2.1e-60 199.2 13.3 8.9e-09 35.9 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EJP64827.1 - 6.7e-18 64.8 7.6 1.2e-17 64.0 7.6 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EJP64827.1 - 8e-16 58.1 0.0 0.00041 20.6 0.0 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EJP64827.1 - 9.3e-07 28.5 0.0 0.17 11.2 0.0 4.7 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 EJP64827.1 - 2.1e-06 26.9 0.2 0.36 9.8 0.0 5.0 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EJP64827.1 - 0.0056 15.4 0.5 0.46 9.1 0.1 3.3 2 1 1 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 EJP64827.1 - 0.028 13.8 0.1 11 5.3 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EJP64827.1 - 0.046 13.7 0.0 21 5.2 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EJP64827.1 - 0.065 11.8 0.4 2.2 6.7 0.2 2.6 1 1 1 2 2 2 0 Cytochrome D1 heme domain Golgin_A5 PF09787.9 EJP64827.1 - 0.07 12.6 2.8 0.1 12.1 2.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 MMS1_N PF10433.9 EJP64827.1 - 0.17 10.4 0.0 0.99 7.9 0.0 1.9 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term TPX2 PF06886.11 EJP64827.1 - 0.19 12.0 4.1 1 9.7 4.1 1.9 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) TSNAXIP1_N PF15739.5 EJP64827.1 - 0.44 10.9 2.3 0.71 10.3 2.3 1.2 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Fungal_trans_2 PF11951.8 EJP64829.1 - 1.6e-05 23.9 0.2 2.5e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ceramidase_alk PF04734.13 EJP64830.1 - 1.8e-208 693.3 0.0 2.1e-208 693.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EJP64830.1 - 2.6e-52 177.1 0.2 4.3e-52 176.4 0.2 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Aa_trans PF01490.18 EJP64831.1 - 1.5e-60 205.1 19.7 1.8e-60 204.8 19.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EJP64831.1 - 4.1e-06 26.1 6.5 4.1e-06 26.1 6.5 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Pkinase PF00069.25 EJP64832.1 - 9.4e-52 176.0 0.0 1.3e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64832.1 - 1.9e-31 109.3 0.0 2.8e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP64832.1 - 1.8e-11 43.9 0.0 2.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJP64832.1 - 0.0079 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP64832.1 - 0.043 13.7 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Phytase PF02333.15 EJP64832.1 - 0.15 11.0 0.0 0.38 9.7 0.0 1.6 2 0 0 2 2 2 0 Phytase Hydrolase PF00702.26 EJP64834.1 - 0.00056 20.3 0.0 0.0018 18.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EJP64834.1 - 0.08 13.0 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Bmt2 PF11968.8 EJP64835.1 - 4.4e-79 265.4 0.0 5.6e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Ribosomal_L23eN PF03939.13 EJP64836.1 - 7.9e-24 83.6 10.0 7.9e-24 83.6 10.0 2.8 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EJP64836.1 - 7.2e-16 58.3 0.4 1.6e-15 57.2 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 CorA PF01544.18 EJP64837.1 - 1.7e-39 135.9 0.0 2.5e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-rbx1 PF12678.7 EJP64838.1 - 9.9e-25 86.6 12.6 1.4e-24 86.2 12.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EJP64838.1 - 3.4e-17 62.3 9.8 4.4e-17 61.9 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EJP64838.1 - 2.1e-06 27.9 13.7 8.2e-05 22.9 13.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJP64838.1 - 3.8e-05 23.4 2.7 3.8e-05 23.4 2.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP64838.1 - 0.002 17.9 11.6 0.038 13.9 11.6 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP64838.1 - 0.2 11.5 10.4 0.69 9.8 4.2 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJP64838.1 - 0.26 11.1 15.8 24 4.8 15.8 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EJP64838.1 - 0.31 11.1 7.0 1.1 9.3 7.0 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 EJP64838.1 - 0.89 9.8 9.2 5.2 7.3 9.4 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EJP64838.1 - 1.6 8.4 14.9 2.4e+02 1.4 14.9 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type PNRC PF15365.6 EJP64839.1 - 2.4e-08 33.5 7.3 2.4e-08 33.5 7.3 3.5 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif NAD_binding_8 PF13450.6 EJP64840.1 - 2e-13 50.4 0.3 4.6e-13 49.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP64840.1 - 3.6e-08 33.0 0.2 1.7e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP64840.1 - 5.1e-07 29.6 5.1 7.6e-06 25.7 1.4 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EJP64840.1 - 2.4e-06 27.2 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP64840.1 - 2.6e-06 26.8 3.2 3.8e-06 26.3 3.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EJP64840.1 - 2e-05 23.9 0.2 4.4e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EJP64840.1 - 4.4e-05 22.3 2.9 0.00037 19.3 1.5 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EJP64840.1 - 0.00025 21.5 1.6 0.17 12.5 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EJP64840.1 - 0.00041 19.8 0.0 0.0074 15.6 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EJP64840.1 - 0.0005 20.1 0.0 0.0022 18.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EJP64840.1 - 0.0037 16.2 0.7 0.0085 15.0 0.7 1.6 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EJP64840.1 - 0.0099 15.0 0.7 0.015 14.4 0.7 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EJP64840.1 - 0.01 15.1 0.9 0.017 14.4 0.9 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 EJP64840.1 - 0.019 14.5 0.2 0.038 13.5 0.2 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family K_oxygenase PF13434.6 EJP64840.1 - 0.037 13.2 2.6 0.63 9.1 0.0 2.4 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EJP64840.1 - 0.085 12.1 0.4 0.14 11.3 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EJP64840.1 - 0.45 9.5 1.3 0.77 8.8 1.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Tyr-DNA_phospho PF06087.12 EJP64841.1 - 2.9e-83 280.1 0.0 3.4e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 EJP64841.1 - 4.9e-05 23.0 3.7 4.9e-05 23.0 3.7 2.5 2 0 0 2 2 2 1 Ubiquitin interaction motif PLDc_2 PF13091.6 EJP64841.1 - 0.0015 18.4 0.0 0.0065 16.3 0.0 2.0 2 0 0 2 2 2 1 PLD-like domain Gti1_Pac2 PF09729.9 EJP64842.1 - 3.5e-63 213.0 0.0 6.3e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.21 EJP64843.1 - 5.3e-14 52.7 0.5 5.3e-14 52.7 0.5 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.22 EJP64844.1 - 1.2e-152 508.6 0.0 1.4e-152 508.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EJP64844.1 - 6.7e-65 219.2 0.0 9.3e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EJP64844.1 - 2.6e-06 26.9 0.2 5.4e-06 25.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EJP64844.1 - 3.4e-06 26.7 0.1 4.9e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP64844.1 - 0.00016 20.9 2.3 0.00016 20.9 2.3 2.4 3 1 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 EJP64844.1 - 0.0072 15.6 0.4 0.0072 15.6 0.4 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EJP64844.1 - 0.029 13.1 3.9 0.1 11.3 1.3 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 EJP64844.1 - 0.059 13.8 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 EJP64844.1 - 0.067 12.4 0.1 0.22 10.7 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.14 EJP64844.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) NepR PF18557.1 EJP64845.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma factor NepR SLATT_fungal PF18142.1 EJP64845.1 - 0.2 11.6 0.3 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain RIP PF00161.19 EJP64846.1 - 3e-57 193.4 0.0 4.2e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Ribosome inactivating protein Sugar_tr PF00083.24 EJP64847.1 - 1.7e-89 300.8 24.2 2.1e-89 300.5 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP64847.1 - 1.6e-13 50.4 43.1 4.9e-09 35.6 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HD_3 PF13023.6 EJP64847.1 - 0.093 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 HD domain Ank_2 PF12796.7 EJP64850.1 - 1.1e-19 70.8 3.8 4.4e-09 36.8 2.8 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP64850.1 - 1.5e-12 47.5 10.1 4.1e-05 23.8 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP64850.1 - 1.8e-12 46.3 3.1 0.008 16.6 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EJP64850.1 - 3.4e-12 46.2 10.0 0.00026 21.3 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EJP64850.1 - 1.9e-11 44.2 6.5 8.1e-05 23.1 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SUIM_assoc PF16619.5 EJP64850.1 - 0.0074 16.3 8.5 0.016 15.2 8.5 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 EJP64850.1 - 0.24 12.4 1.0 0.4 11.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 EJP64850.1 - 0.49 10.0 5.4 0.76 9.3 5.4 1.2 1 0 0 1 1 1 0 Spt20 family Fungal_trans PF04082.18 EJP64852.1 - 2.3e-05 23.6 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.12 EJP64853.1 - 0.85 10.2 7.9 9.9 6.7 0.1 3.8 3 1 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region CMD PF02627.20 EJP64854.1 - 0.11 12.5 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Lactamase_B PF00753.27 EJP64856.1 - 7e-05 22.9 0.3 0.0011 19.0 0.1 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EJP64856.1 - 0.1 12.1 0.0 1.7 8.1 0.0 2.2 1 1 1 2 2 2 0 Beta-lactamase superfamily domain GAD-like PF08887.11 EJP64856.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 GAD-like domain Cupin_1 PF00190.22 EJP64857.1 - 6.2e-17 61.6 0.9 9e-17 61.1 0.9 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EJP64857.1 - 0.00082 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain LamB_YcsF PF03746.16 EJP64858.1 - 5.1e-84 281.7 0.0 5.8e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 EJP64859.1 - 5.1e-78 262.3 0.0 8.4e-78 261.6 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 EJP64859.1 - 5.2e-50 169.9 0.0 1e-49 168.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EJP64859.1 - 1.6e-37 128.4 0.0 3.6e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 EJP64859.1 - 1.3e-29 103.4 0.0 3e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 EJP64859.1 - 1.6e-28 99.0 0.0 3.1e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Fungal_trans PF04082.18 EJP64859.1 - 3.5e-15 55.8 0.0 5.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Biotin_lipoyl PF00364.22 EJP64859.1 - 2.3e-09 36.9 0.2 7.2e-09 35.4 0.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EJP64859.1 - 9.5e-06 25.3 0.0 2.4e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EJP64859.1 - 1.8e-05 24.5 0.1 4.9e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.22 EJP64859.1 - 0.00054 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 EJP64859.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain G-alpha PF00503.20 EJP64860.1 - 7.8e-112 373.9 0.1 9.1e-112 373.7 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EJP64860.1 - 2.1e-13 50.1 0.2 5.9e-08 32.4 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJP64860.1 - 0.00024 20.5 0.7 0.05 12.9 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EJP64860.1 - 0.0054 17.0 0.1 1.8 8.8 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EJP64860.1 - 0.033 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_15 PF13175.6 EJP64860.1 - 0.043 13.5 0.2 0.067 12.9 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EJP64860.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Spermine_synth PF01564.17 EJP64861.1 - 6.4e-72 240.9 0.0 9.2e-72 240.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EJP64861.1 - 2.1e-26 91.6 0.1 3.5e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EJP64861.1 - 0.011 16.4 0.0 0.022 15.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CHAP PF05257.16 EJP64861.1 - 0.13 12.9 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 CHAP domain CN_hydrolase PF00795.22 EJP64862.1 - 4.3e-58 196.7 0.0 5.1e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase WD40 PF00400.32 EJP64863.1 - 4.9e-36 122.1 17.7 9.1e-10 39.0 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP64863.1 - 2e-14 53.7 0.6 0.019 15.2 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP64863.1 - 4.2e-08 32.5 0.1 0.45 9.4 0.0 4.5 1 1 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EJP64863.1 - 0.00035 19.4 3.1 0.11 11.2 0.1 3.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EJP64863.1 - 0.0015 17.5 0.1 0.0015 17.5 0.1 2.6 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 EJP64863.1 - 0.004 16.3 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Hira PF07569.11 EJP64863.1 - 0.026 14.2 0.6 22 4.7 0.1 3.3 1 1 1 2 2 2 0 TUP1-like enhancer of split Frtz PF11768.8 EJP64863.1 - 0.055 11.8 0.0 0.13 10.6 0.0 1.6 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 EJP64863.1 - 0.071 12.6 0.0 0.62 9.6 0.0 2.2 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 TMEM234 PF10639.9 EJP64865.1 - 4.7e-33 113.7 0.2 6.2e-33 113.3 0.2 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EJP64865.1 - 0.0014 18.8 6.6 0.046 13.9 6.6 2.1 1 1 0 1 1 1 1 EamA-like transporter family Proteasome PF00227.26 EJP64867.1 - 1.5e-48 164.8 0.1 2e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJP64867.1 - 3.1e-11 42.7 0.2 5.4e-11 42.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.9 EJP64868.1 - 8.4e-19 67.2 0.0 1.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) SDA1 PF05285.12 EJP64868.1 - 0.14 11.6 27.2 0.22 10.9 27.2 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EJP64868.1 - 0.47 8.6 31.4 0.66 8.1 31.4 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 EJP64868.1 - 0.89 9.1 27.9 0.034 13.7 21.8 1.7 2 0 0 2 2 2 0 PPP4R2 SAPS PF04499.15 EJP64868.1 - 2.5 6.8 11.0 3.7 6.2 11.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PhyH PF05721.13 EJP64869.1 - 2.1e-56 191.6 0.0 2.8e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4271 PF14093.6 EJP64870.1 - 0.031 14.2 1.2 0.053 13.4 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Clc-like PF07062.12 EJP64870.1 - 0.11 12.0 4.1 0.37 10.2 4.0 1.8 1 1 1 2 2 2 0 Clc-like DUF2534 PF10749.9 EJP64870.1 - 0.13 12.5 1.1 0.14 12.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) DUF2207 PF09972.9 EJP64870.1 - 0.13 11.0 0.4 0.22 10.3 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF997 PF06196.12 EJP64870.1 - 0.5 10.4 4.6 6.2 6.9 0.0 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF997) FtsX PF02687.21 EJP64870.1 - 2.8 8.5 8.2 1.2 9.7 4.6 2.0 2 0 0 2 2 2 0 FtsX-like permease family GCS PF03074.16 EJP64871.1 - 1.1e-176 587.6 0.0 1.4e-176 587.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase APH PF01636.23 EJP64872.1 - 1.5e-07 31.6 0.7 0.00018 21.5 0.4 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Endosulfine PF04667.17 EJP64873.1 - 2.8e-27 94.7 0.1 4.8e-27 93.9 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region UPF0160 PF03690.13 EJP64874.1 - 5.6e-127 423.8 0.0 6.5e-127 423.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) MFS_1 PF07690.16 EJP64876.1 - 2.2e-27 95.9 38.1 1.2e-26 93.5 38.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP64876.1 - 1.3e-09 37.5 20.4 5.9e-06 25.4 4.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EJP64876.1 - 2.4e-09 36.3 17.8 2.9e-09 36.0 4.8 2.2 1 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EJP64876.1 - 0.0002 20.3 8.9 0.04 12.8 4.8 2.2 2 0 0 2 2 2 2 MFS_1 like family DUF2839 PF10999.8 EJP64876.1 - 0.13 12.6 0.1 0.47 10.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Cyclase PF04199.13 EJP64877.1 - 2.3e-16 60.3 0.1 3e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short PF00106.25 EJP64878.1 - 2e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP64878.1 - 6.4e-05 22.6 0.0 8.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_1 PF00561.20 EJP64879.1 - 6.8e-27 94.7 0.0 2.5e-26 92.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EJP64879.1 - 7.8e-18 64.5 0.1 2.3e-17 63.0 0.1 1.8 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 EJP64879.1 - 0.0002 20.7 0.2 1.6 7.9 0.0 3.3 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP64879.1 - 0.0024 18.5 7.0 0.091 13.3 7.0 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Epimerase PF01370.21 EJP64880.1 - 2.5e-22 79.5 0.1 4.9e-22 78.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP64880.1 - 3.3e-12 46.4 0.0 5.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EJP64880.1 - 2.1e-11 43.4 0.0 6.3e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EJP64880.1 - 5.9e-09 36.1 2.7 4e-08 33.4 1.1 2.5 2 1 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EJP64880.1 - 1e-06 28.1 0.1 2.3e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EJP64880.1 - 0.00079 18.6 0.4 0.0015 17.7 0.4 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EJP64880.1 - 0.001 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EJP64880.1 - 0.0018 18.2 0.4 0.004 17.1 0.4 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EJP64880.1 - 0.026 14.1 0.1 0.067 12.7 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 EJP64880.1 - 0.054 13.0 1.8 0.063 12.7 0.2 2.0 3 0 0 3 3 3 0 short chain dehydrogenase MFS_1 PF07690.16 EJP64881.1 - 2.6e-30 105.6 42.2 2.6e-30 105.6 42.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EJP64881.1 - 8.6e-10 38.4 11.5 8.6e-10 38.4 11.5 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB SKG6 PF08693.10 EJP64881.1 - 0.065 12.7 2.2 0.95 8.9 2.1 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Fungal_trans_2 PF11951.8 EJP64882.1 - 8.5e-58 196.0 0.0 1.2e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64882.1 - 3e-10 40.0 28.6 1.4e-05 25.1 4.4 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 EJP64883.1 - 7e-51 173.1 0.5 9.3e-51 172.7 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EJP64883.1 - 6.9e-06 25.2 0.1 5e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EJP64883.1 - 2.2e-05 25.1 4.9 3.3e-05 24.6 4.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EJP64883.1 - 0.0031 17.0 0.0 0.12 11.8 0.0 2.2 1 1 0 2 2 2 1 Prolyl oligopeptidase family Patatin PF01734.22 EJP64883.1 - 0.037 14.2 0.1 0.055 13.6 0.1 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase FAD_binding_3 PF01494.19 EJP64884.1 - 4.7e-17 62.3 0.1 6.2e-11 42.1 0.1 2.4 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 EJP64884.1 - 4.4e-05 23.6 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP64884.1 - 0.00021 21.0 0.8 0.0019 17.8 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP64884.1 - 0.0017 18.9 0.0 0.024 15.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EJP64884.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EJP64884.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EJP64884.1 - 0.028 13.5 0.0 0.74 8.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EJP64884.1 - 0.054 12.7 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EJP64884.1 - 0.085 13.1 0.0 0.44 10.8 0.0 2.3 3 0 0 3 3 3 0 TrkA-N domain Arylsulfotran_2 PF14269.6 EJP64885.1 - 1.8e-56 191.7 0.0 2.6e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EJP64885.1 - 1.5e-16 60.3 0.0 3.6e-16 59.0 0.0 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF4719 PF15843.5 EJP64885.1 - 0.015 15.4 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) HEAT_2 PF13646.6 EJP64886.1 - 1.8e-19 69.9 21.3 4.4e-11 43.0 2.8 3.9 1 1 4 5 5 5 4 HEAT repeats HEAT PF02985.22 EJP64886.1 - 7.4e-09 35.1 13.7 0.047 14.0 0.0 6.4 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 EJP64886.1 - 8.8e-07 29.3 17.9 0.26 11.8 0.0 6.0 5 2 2 7 7 6 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EJP64886.1 - 0.00053 20.5 0.6 2.4 8.8 0.0 4.3 1 1 3 4 4 4 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EJP64886.1 - 0.00063 19.9 0.0 0.22 11.7 0.0 3.3 1 1 3 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 EJP64886.1 - 0.0025 18.2 0.6 7.5 7.0 0.1 4.8 2 2 2 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cnd1 PF12717.7 EJP64886.1 - 0.0055 16.8 4.2 15 5.6 0.1 4.0 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TetR_C_16 PF17920.1 EJP64886.1 - 0.0065 16.7 10.5 14 6.0 0.2 5.7 4 2 2 6 6 6 0 Tetracyclin repressor-like, C-terminal domain DUF4158 PF13700.6 EJP64886.1 - 0.0071 16.2 1.8 0.31 10.8 0.1 2.9 2 2 2 4 4 4 1 Domain of unknown function (DUF4158) Cohesin_HEAT PF12765.7 EJP64886.1 - 0.014 15.7 4.3 29 5.1 0.0 4.7 4 1 1 5 5 5 0 HEAT repeat associated with sister chromatid cohesion VHS PF00790.19 EJP64886.1 - 0.017 15.0 1.0 0.28 11.0 0.0 2.8 1 1 3 4 4 4 0 VHS domain SoPB_HTH PF18090.1 EJP64886.1 - 0.045 13.9 0.3 18 5.5 0.0 3.1 2 1 1 3 3 3 0 Centromere-binding protein HTH domain IFRD PF05004.13 EJP64886.1 - 0.087 11.9 0.6 14 4.7 0.0 2.9 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.7 EJP64886.1 - 0.21 10.8 0.3 9.8 5.3 0.1 2.9 1 1 2 4 4 4 0 Nuclear condensing complex subunits, C-term domain RHH_5 PF07878.11 EJP64886.1 - 1.9 8.4 7.8 17 5.4 0.0 5.0 6 0 0 6 6 6 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 KfrA_N PF11740.8 EJP64886.1 - 2.5 8.8 8.2 32 5.3 0.2 4.0 1 1 3 4 4 4 0 Plasmid replication region DNA-binding N-term Glyco_hydro_3 PF00933.21 EJP64887.1 - 4.1e-42 144.7 0.0 6.5e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EJP64887.1 - 6.5e-41 140.5 0.0 1.2e-40 139.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EJP64887.1 - 4.3e-24 84.4 0.2 7.4e-24 83.7 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain GATA PF00320.27 EJP64889.1 - 4.2e-16 58.3 3.5 7e-16 57.5 3.5 1.4 1 0 0 1 1 1 1 GATA zinc finger FHA PF00498.26 EJP64891.1 - 1.1e-14 54.5 0.0 2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EJP64891.1 - 0.0015 18.8 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 EJP64891.1 - 0.038 14.2 0.0 0.62 10.3 0.0 2.4 2 1 0 2 2 2 0 FHA domain IFRD PF05004.13 EJP64892.1 - 8.9e-52 176.1 0.3 1.2e-51 175.7 0.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 EJP64892.1 - 0.0026 18.1 3.8 0.24 11.8 0.2 3.4 2 2 0 2 2 2 2 HEAT repeats HEAT PF02985.22 EJP64892.1 - 0.2 12.0 1.4 9.2 6.8 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat Tubulin PF00091.25 EJP64893.1 - 3.5e-58 197.1 0.1 6.9e-58 196.1 0.1 1.5 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EJP64893.1 - 1.8e-45 154.2 0.7 3.6e-45 153.2 0.2 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EJP64893.1 - 0.0039 17.5 0.0 0.0092 16.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EJP64893.1 - 0.013 15.2 0.1 0.078 12.7 0.0 2.2 3 0 0 3 3 3 0 Tubulin domain Ran_BP1 PF00638.18 EJP64894.1 - 4.6e-09 36.6 0.0 1.1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 EJP64894.1 - 4.6e-06 27.4 34.9 0.00012 22.8 14.4 10.1 3 3 5 9 9 9 3 Nucleoporin FG repeat region ABC_tran PF00005.27 EJP64895.1 - 4.6e-28 98.4 0.0 8.5e-14 52.2 0.0 3.5 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP64895.1 - 4.8e-12 46.1 20.0 5.6e-08 32.8 9.7 4.2 4 1 1 5 5 5 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP64895.1 - 0.011 15.2 0.8 3.5 7.0 0.2 3.1 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain SID-1_RNA_chan PF13965.6 EJP64895.1 - 0.076 11.4 0.1 0.2 10.0 0.1 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MFS_1 PF07690.16 EJP64896.1 - 0.00044 19.3 48.1 0.012 14.6 42.9 3.7 1 1 1 2 2 2 1 Major Facilitator Superfamily YrhK PF14145.6 EJP64896.1 - 0.0026 17.6 3.8 0.0089 15.9 3.8 2.0 1 0 0 1 1 1 1 YrhK-like protein N_BRCA1_IG PF16158.5 EJP64897.1 - 1.1e-30 106.4 0.0 2.8e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene DUF3632 PF12311.8 EJP64897.1 - 4e-28 99.0 1.2 8e-28 98.0 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ZZ PF00569.17 EJP64897.1 - 4.3e-23 80.8 54.8 2.4e-08 33.6 7.8 4.6 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 EJP64897.1 - 0.021 15.1 53.5 0.048 14.0 10.7 5.0 5 0 0 5 5 5 0 C1 domain Baculo_IE-1 PF05290.11 EJP64897.1 - 7.2 6.6 11.9 0.21 11.5 0.7 2.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF5308 PF17233.2 EJP64898.1 - 3.8e-40 137.8 15.4 4.3e-26 92.1 6.2 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5308) Btz PF09405.10 EJP64899.1 - 7.1e-18 65.1 1.7 1.9e-17 63.7 1.7 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding DUF3463 PF11946.8 EJP64901.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Methyltransf_34 PF11312.8 EJP64902.1 - 2.3e-107 358.8 0.3 2.7e-107 358.5 0.3 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase MID_MedPIWI PF18296.1 EJP64902.1 - 0.084 12.6 0.5 0.16 11.8 0.5 1.4 1 0 0 1 1 1 0 MID domain of medPIWI SUIM_assoc PF16619.5 EJP64902.1 - 0.12 12.5 0.4 0.12 12.5 0.4 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Syja_N PF02383.18 EJP64903.1 - 6.1e-93 311.6 0.0 8.4e-93 311.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EJP64903.1 - 7.1e-39 132.1 0.0 1.3e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase DUF5365 PF17326.2 EJP64903.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5365) ATP-synt_C PF00137.21 EJP64904.1 - 7.6e-35 119.1 34.2 6.9e-22 77.6 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ERG4_ERG24 PF01222.17 EJP64905.1 - 2.8e-134 448.1 22.4 3.2e-134 447.9 22.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3720 PF12517.8 EJP64905.1 - 0.36 11.8 5.1 0.7 10.9 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) SRP-alpha_N PF04086.13 EJP64905.1 - 3.7 7.4 8.2 5.4 6.8 8.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.16 EJP64906.1 - 7.6e-33 113.9 29.9 7.6e-33 113.9 29.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Holin_BhlA PF10960.8 EJP64906.1 - 0.011 15.7 0.1 0.46 10.5 0.0 3.0 2 1 1 3 3 3 0 BhlA holin family Wzz PF02706.15 EJP64906.1 - 0.71 10.2 3.8 6.3 7.2 0.0 3.6 3 0 0 3 3 3 0 Chain length determinant protein DUF872 PF05915.12 EJP64906.1 - 4.9 7.4 9.0 3.6 7.8 0.1 3.5 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) PLDc PF00614.22 EJP64908.1 - 4.2e-16 58.4 3.5 5e-07 29.6 0.2 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EJP64908.1 - 6.2e-13 48.8 0.5 5.9e-07 29.4 0.0 3.3 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 EJP64908.1 - 8.4e-08 32.2 0.2 2.8e-06 27.3 0.0 3.4 4 0 0 4 4 4 1 PX domain COQ7 PF03232.13 EJP64909.1 - 4.6e-70 234.8 0.7 5.8e-70 234.5 0.7 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EJP64909.1 - 0.01 16.3 0.4 0.018 15.4 0.0 1.7 2 1 0 2 2 2 1 Rubrerythrin Vac17 PF17321.2 EJP64909.1 - 0.032 13.7 1.8 0.041 13.3 1.8 1.1 1 0 0 1 1 1 0 Vacuole-related protein 17 Vitellogenin_N PF01347.22 EJP64909.1 - 0.038 12.4 0.0 0.047 12.1 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region B12D PF06522.11 EJP64909.1 - 0.063 13.1 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit SR-25 PF10500.9 EJP64909.1 - 6.7 6.2 7.0 9.8 5.7 7.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Plus-3 PF03126.18 EJP64910.1 - 1.2e-25 90.1 0.0 2.4e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain GDPD PF03009.17 EJP64911.1 - 1.7e-19 70.6 0.1 4.7e-14 52.7 0.1 2.4 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EJP64911.1 - 0.16 12.5 8.2 15 6.2 2.2 3.4 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family SET PF00856.28 EJP64912.1 - 5.3e-05 23.7 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.10 EJP64913.1 - 1.6e-36 125.3 0.0 3.8e-36 124.1 0.0 1.6 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EJP64913.1 - 5.9e-21 74.7 0.0 1.5e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJP64913.1 - 4.3e-09 36.1 0.2 3e-07 30.1 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EJP64913.1 - 0.0018 18.4 0.8 0.089 12.8 0.2 2.9 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 EJP64913.1 - 0.0024 17.5 0.1 0.19 11.2 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EJP64913.1 - 0.0027 17.6 0.4 0.26 11.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase TGS PF02824.21 EJP64913.1 - 0.11 12.6 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 TGS domain MMR_HSR1_Xtn PF16897.5 EJP64913.1 - 0.14 12.2 0.2 0.36 10.9 0.2 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain F-box-like PF12937.7 EJP64914.1 - 0.00042 20.1 1.0 0.0011 18.8 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP64914.1 - 0.03 14.2 0.5 0.094 12.6 0.5 1.9 1 0 0 1 1 1 0 F-box domain TPR_1 PF00515.28 EJP64914.1 - 0.1 12.5 1.1 13 5.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EJP64914.1 - 0.16 12.2 5.5 0.41 10.9 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_4 PF01063.19 EJP64915.1 - 2.3e-25 89.8 0.0 3.2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV TPR_2 PF07719.17 EJP64916.1 - 1.1e-41 137.6 13.5 0.00025 20.9 0.0 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 EJP64916.1 - 6.4e-41 136.6 13.3 3.5e-05 23.4 0.1 11.4 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.6 EJP64916.1 - 4.5e-26 89.3 1.6 2.5e-05 24.3 0.0 8.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EJP64916.1 - 1e-24 84.6 14.9 0.0025 17.9 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 EJP64916.1 - 1.2e-19 70.7 6.2 1.9e-05 25.2 0.1 6.1 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EJP64916.1 - 2.4e-19 68.7 14.6 4.9e-05 22.9 0.0 8.7 7 1 1 8 8 8 3 TPR repeat TPR_19 PF14559.6 EJP64916.1 - 9.6e-17 61.3 15.5 2.6e-05 24.7 1.7 6.7 6 1 2 8 8 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EJP64916.1 - 1.3e-14 53.6 10.1 0.013 16.2 0.3 9.0 3 2 6 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 EJP64916.1 - 4.7e-14 52.3 1.8 0.0059 16.7 0.1 6.5 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EJP64916.1 - 6e-14 52.1 23.3 0.015 15.5 3.9 8.4 3 1 6 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 EJP64916.1 - 7.5e-11 41.3 7.9 0.047 13.7 0.2 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP64916.1 - 1.9e-07 30.8 0.9 1.6e-05 24.4 0.9 2.8 1 1 2 3 3 3 2 MalT-like TPR region ANAPC3 PF12895.7 EJP64916.1 - 2e-06 27.9 7.0 0.072 13.3 0.5 5.2 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 EJP64916.1 - 2.6e-06 26.8 3.4 0.01 15.3 0.0 4.3 4 0 0 4 4 4 2 SHNi-TPR TPR_10 PF13374.6 EJP64916.1 - 1.9e-05 24.4 20.0 0.74 9.8 0.9 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EJP64916.1 - 2.4e-05 24.7 21.5 0.2 12.3 0.0 8.4 9 0 0 9 9 7 1 Tetratricopeptide repeat MAS20 PF02064.15 EJP64916.1 - 8.8e-05 22.6 9.9 0.0017 18.5 0.8 4.4 4 1 1 5 5 4 1 MAS20 protein import receptor NARP1 PF12569.8 EJP64916.1 - 0.0033 16.4 18.7 0.073 12.0 0.2 4.4 4 1 1 5 5 5 2 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 EJP64916.1 - 0.009 16.1 2.9 2.5 8.1 0.0 4.6 6 0 0 6 6 4 1 Domain of Unknown Function (DUF3856) PSD5 PF07637.11 EJP64916.1 - 0.033 14.5 1.2 0.32 11.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) GTA_TIM PF13547.6 EJP64916.1 - 0.075 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 GTA TIM-barrel-like domain MIT PF04212.18 EJP64916.1 - 0.14 12.3 12.4 9.5 6.4 0.3 6.4 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 EJP64916.1 - 0.23 11.9 8.6 1.3 9.5 0.0 4.5 2 2 2 5 5 5 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 EJP64916.1 - 0.46 10.8 11.2 1.9 8.9 0.2 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat Sel1 PF08238.12 EJP64916.1 - 8.2 7.3 11.5 0.74 10.6 0.3 4.5 5 0 0 5 5 3 0 Sel1 repeat Syntaxin PF00804.25 EJP64917.1 - 2.1e-24 86.3 8.9 2.1e-24 86.3 8.9 1.4 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 EJP64917.1 - 1.9e-10 40.5 0.9 1.9e-10 40.5 0.9 2.0 2 0 0 2 2 1 1 SNARE domain Syntaxin_2 PF14523.6 EJP64917.1 - 3e-05 24.3 4.9 3e-05 24.3 4.9 2.3 2 0 0 2 2 2 1 Syntaxin-like protein FlgN PF05130.12 EJP64917.1 - 0.036 14.6 3.1 0.036 14.6 3.1 2.5 2 1 0 2 2 2 0 FlgN protein PBP1_TM PF14812.6 EJP64917.1 - 0.038 14.3 1.0 0.07 13.5 0.1 1.9 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMCO5 PF14992.6 EJP64917.1 - 0.054 13.1 9.1 0.63 9.6 9.1 2.2 1 1 0 1 1 1 0 TMCO5 family SLATT_1 PF18181.1 EJP64917.1 - 0.056 13.4 4.8 0.84 9.6 0.3 2.8 1 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 BatA PF07584.11 EJP64917.1 - 0.078 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF5383 PF17355.2 EJP64917.1 - 0.083 13.3 1.6 6.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) T2SSF PF00482.23 EJP64917.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F VirB8 PF04335.13 EJP64917.1 - 0.17 11.7 7.1 0.86 9.4 0.4 3.1 2 1 1 3 3 3 0 VirB8 protein ETRAMP PF09716.10 EJP64917.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) IZUMO PF15005.6 EJP64917.1 - 0.18 12.3 3.3 7.6 7.0 0.1 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated LMBR1 PF04791.16 EJP64917.1 - 0.38 9.6 8.9 0.81 8.5 9.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF2207 PF09972.9 EJP64917.1 - 0.41 9.4 4.6 0.13 11.0 0.1 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MCU PF04678.13 EJP64917.1 - 0.58 10.2 8.2 0.062 13.4 0.9 2.4 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Prominin PF05478.11 EJP64917.1 - 1.6 6.6 7.6 1.1 7.1 0.4 2.2 2 0 0 2 2 2 0 Prominin Muted PF14942.6 EJP64917.1 - 1.9 8.8 10.4 1.1 9.6 2.9 2.5 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Laminin_II PF06009.12 EJP64917.1 - 3.4 7.7 10.9 0.98 9.4 3.4 3.0 2 1 0 3 3 3 0 Laminin Domain II Mod_r PF07200.13 EJP64917.1 - 6.8 6.8 17.8 0.36 10.9 6.0 2.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FUSC PF04632.12 EJP64917.1 - 9.7 4.6 9.7 1.8 7.0 2.9 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Brix PF04427.18 EJP64918.1 - 9.3e-31 107.4 0.0 1.2e-30 107.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.10 EJP64919.1 - 2.1e-68 229.1 3.4 2.8e-68 228.7 1.1 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EJP64919.1 - 1.9e-61 207.2 0.0 8.3e-61 205.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EJP64919.1 - 2.5e-55 188.1 2.9 3.3e-31 109.0 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EJP64919.1 - 4.6e-31 106.9 0.0 9.6e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EJP64919.1 - 2.5e-13 50.2 0.3 5.3e-12 45.8 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP64919.1 - 1.9e-10 41.3 0.0 7e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EJP64919.1 - 3.3e-06 27.2 0.0 7.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EJP64919.1 - 3.1e-05 23.4 1.5 0.00028 20.3 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EJP64919.1 - 0.00019 21.3 0.3 0.91 9.2 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 EJP64919.1 - 0.00026 20.3 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 EJP64919.1 - 0.00035 20.2 0.1 0.0058 16.2 0.0 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EJP64919.1 - 0.0005 20.0 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 Helicase DEAD PF00270.29 EJP64919.1 - 0.0035 17.1 0.1 0.0083 15.9 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 EJP64919.1 - 0.0047 16.3 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_10 PF12846.7 EJP64919.1 - 0.0071 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Ribosomal_S13_N PF08069.12 EJP64919.1 - 0.018 15.1 0.0 0.073 13.1 0.0 2.1 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain SRP54 PF00448.22 EJP64919.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 EJP64919.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 EJP64919.1 - 0.18 11.2 0.0 0.54 9.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 EJP64919.1 - 0.26 11.7 0.5 0.63 10.5 0.5 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Prok-RING_2 PF14445.6 EJP64919.1 - 1.5 9.1 4.1 2.2 8.5 1.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 zf-UBP PF02148.19 EJP64919.1 - 5.4 7.4 6.2 15 6.0 6.2 1.8 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DnaJ PF00226.31 EJP64920.1 - 3.7e-19 68.6 0.7 6.2e-19 67.9 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.22 EJP64921.1 - 1.2e-69 234.8 5.5 1.5e-69 234.5 5.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.21 EJP64922.1 - 1.2e-91 308.1 0.3 1.4e-54 186.1 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EJP64922.1 - 8.5e-37 125.8 0.0 1.8e-36 124.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EJP64922.1 - 1e-27 97.0 0.0 2e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EJP64922.1 - 4e-07 29.7 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EJP64922.1 - 1.1e-05 24.7 0.1 0.00011 21.4 0.1 2.1 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 EJP64922.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC UQ_con PF00179.26 EJP64923.1 - 3.4e-48 162.8 0.0 3.9e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP64923.1 - 0.00014 21.6 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Pex19 PF04614.12 EJP64924.1 - 1.5e-76 257.4 12.2 1.5e-76 257.4 12.2 1.7 2 0 0 2 2 2 1 Pex19 protein family GET2 PF08690.10 EJP64924.1 - 0.00091 19.0 14.5 0.023 14.4 5.9 2.5 1 1 1 2 2 2 2 GET complex subunit GET2 KIX_2 PF16987.5 EJP64924.1 - 0.058 13.4 1.8 0.52 10.3 0.1 2.6 2 0 0 2 2 2 0 KIX domain ABC_tran_Xtn PF12848.7 EJP64924.1 - 0.23 11.5 1.5 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 ABC transporter FliE PF02049.18 EJP64924.1 - 1 9.5 11.6 12 6.1 2.8 3.6 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE Com_YlbF PF06133.11 EJP64925.1 - 0.044 14.4 0.5 0.09 13.4 0.5 1.5 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Ribosomal_L14e PF01929.17 EJP64925.1 - 0.054 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L14 DNA_pol_phi PF04931.13 EJP64925.1 - 2.2 6.3 11.1 2.6 6.1 11.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi ABC1 PF03109.16 EJP64926.1 - 6e-32 110.3 0.0 1e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family MRC1 PF09444.10 EJP64927.1 - 6.5e-43 146.7 16.8 6.5e-43 146.7 16.8 6.8 5 2 2 7 7 7 1 MRC1-like domain NAD_binding_5 PF07994.12 EJP64928.1 - 3.8e-147 489.8 0.2 4.4e-147 489.6 0.2 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EJP64928.1 - 1.8e-45 153.6 0.5 4.3e-45 152.4 0.5 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LIM PF00412.22 EJP64929.1 - 1.1e-20 73.6 19.5 1e-11 44.9 1.9 3.0 3 0 0 3 3 3 2 LIM domain zf_UBZ PF18439.1 EJP64929.1 - 0.00051 19.6 9.2 0.013 15.1 0.4 3.6 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger WRC PF08879.10 EJP64929.1 - 0.13 12.0 0.5 1.3 8.7 0.3 2.3 2 0 0 2 2 2 0 WRC zinc_ribbon_2 PF13240.6 EJP64929.1 - 0.14 12.0 1.8 9.5 6.1 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 EJP64929.1 - 1.9 9.1 10.0 2.2 8.9 0.6 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP64929.1 - 5.2 8.2 6.4 9.2 7.4 0.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3405 PF11885.8 EJP64930.1 - 7.6e-189 628.6 8.4 1e-188 628.2 8.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Formyl_trans_N PF00551.19 EJP64931.1 - 2.1e-22 79.7 0.0 3e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Med1 PF10744.9 EJP64933.1 - 4.7e-123 411.3 0.0 6.7e-123 410.8 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 SUR7 PF06687.12 EJP64935.1 - 2.6e-15 56.6 4.2 2.6e-15 56.6 4.2 1.8 1 1 1 2 2 2 1 SUR7/PalI family PMP22_Claudin PF00822.20 EJP64935.1 - 0.0037 17.2 3.7 0.0037 17.2 3.7 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family RGI1 PF10843.8 EJP64935.1 - 0.18 11.5 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Respiratory growth induced protein 1 Hum_adeno_E3A PF05393.11 EJP64935.1 - 0.18 11.8 1.3 0.54 10.3 0.6 2.1 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein SLATT_4 PF18186.1 EJP64935.1 - 0.69 9.5 1.9 1.1 8.9 1.3 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Holin_SPP1 PF04688.13 EJP64935.1 - 7.6 6.8 7.3 0.74 10.0 1.9 2.1 2 0 0 2 2 2 0 SPP1 phage holin ORMDL PF04061.14 EJP64937.1 - 2.5e-58 195.7 4.7 3e-58 195.5 4.7 1.1 1 0 0 1 1 1 1 ORMDL family zf-CCHC PF00098.23 EJP64938.1 - 0.0039 17.2 9.4 0.011 15.7 1.0 5.5 6 0 0 6 6 6 3 Zinc knuckle zf-CCHC_2 PF13696.6 EJP64938.1 - 5.7 6.9 17.1 3 7.7 2.2 3.5 3 0 0 3 3 3 0 Zinc knuckle Cys_rich_CPXG PF14255.6 EJP64938.1 - 9.7 6.2 8.3 12 5.9 0.1 3.5 3 0 0 3 3 3 0 Cysteine-rich CPXCG Apt1 PF10351.9 EJP64939.1 - 0.02 13.8 4.4 0.03 13.2 4.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1501 PF07394.12 EJP64939.1 - 0.055 12.5 0.2 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) YL1 PF05764.13 EJP64939.1 - 3 7.9 10.3 0.12 12.5 4.4 1.5 2 0 0 2 2 2 0 YL1 nuclear protein RRM_1 PF00076.22 EJP64940.1 - 2.7e-18 65.6 0.1 1.4e-11 44.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP64940.1 - 0.02 15.0 0.9 0.051 13.7 0.0 2.1 3 0 0 3 3 3 0 RNA recognition motif PBP1_TM PF14812.6 EJP64940.1 - 6.4 7.2 30.9 0.76 10.2 13.2 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Macoilin PF09726.9 EJP64941.1 - 1.2 7.7 5.8 1.2 7.6 5.8 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 EJP64941.1 - 3.2 6.3 6.2 3.7 6.1 6.2 1.1 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 EJP64941.1 - 3.3 6.5 7.3 4.2 6.1 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cut8 PF08559.10 EJP64942.1 - 1.8e-75 253.6 0.3 3.4e-75 252.8 0.0 1.5 2 0 0 2 2 2 1 Cut8, nuclear proteasome tether protein Rad52_Rad22 PF04098.15 EJP64942.1 - 3.1e-58 196.0 0.0 5.7e-58 195.2 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PHINT_rpt PF14882.6 EJP64942.1 - 0.027 14.7 0.3 0.075 13.3 0.3 1.8 1 0 0 1 1 1 0 Phage-integrase repeat unit TPR_12 PF13424.6 EJP64943.1 - 3.9e-08 33.5 0.5 0.33 11.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP64943.1 - 0.00014 21.7 2.2 0.097 12.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TetR_C_11 PF16859.5 EJP64943.1 - 0.0037 17.6 0.2 0.012 15.9 0.2 1.8 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TPR_1 PF00515.28 EJP64943.1 - 0.0062 16.3 1.2 9.4 6.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP64943.1 - 0.018 15.1 0.1 2.9 8.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 EJP64944.1 - 7.1e-11 42.1 0.1 8.2e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2 PF00096.26 EJP64945.1 - 1.2e-07 31.8 50.5 0.0041 17.5 8.0 6.4 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP64945.1 - 0.00012 22.6 52.3 0.039 14.8 6.9 7.5 8 1 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EJP64945.1 - 0.0017 18.5 4.8 0.2 11.8 0.3 2.6 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_7 PF15269.6 EJP64945.1 - 1.3 9.2 8.7 11 6.2 1.3 2.8 2 0 0 2 2 2 0 Zinc-finger zf-C2H2_4 PF13894.6 EJP64946.1 - 0.00053 20.6 11.8 0.074 13.9 0.2 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP64946.1 - 0.0016 18.8 16.4 0.0055 17.1 0.3 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EJP64946.1 - 0.037 14.3 4.9 0.12 12.7 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJP64946.1 - 0.049 14.0 1.1 2.2 8.8 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 EJP64946.1 - 0.19 12.4 1.3 0.49 11.1 1.3 1.7 1 0 0 1 1 1 0 TRAF-type zinc finger AIM24 PF01987.17 EJP64948.1 - 4.5e-41 140.9 0.1 8.9e-41 139.9 0.1 1.5 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 CTP_synth_N PF06418.14 EJP64949.1 - 4.1e-120 400.0 0.1 5.3e-120 399.7 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EJP64949.1 - 4.2e-49 166.9 0.0 6.2e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EJP64949.1 - 5e-05 23.2 0.0 0.0002 21.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 EJP64949.1 - 0.012 15.6 0.0 0.028 14.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pkinase PF00069.25 EJP64952.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP64952.1 - 0.025 13.9 0.0 0.74 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Fungal_trans_2 PF11951.8 EJP64953.1 - 1.4e-11 43.8 0.0 1.9e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MDMPI_N PF11716.8 EJP64953.1 - 0.026 15.2 0.8 0.026 15.2 0.8 2.4 1 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain TRP PF06011.12 EJP64955.1 - 2.8e-155 517.2 29.2 3.5e-155 516.9 29.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EJP64955.1 - 4.1e-40 137.4 0.1 6.7e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF3433 PF11915.8 EJP64956.1 - 1.1e-35 121.9 23.1 8.9e-20 71.0 0.4 4.5 3 1 1 4 4 4 2 Protein of unknown function (DUF3433) FixQ PF05545.11 EJP64956.1 - 3.7 7.6 4.7 20 5.3 4.7 2.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ FSA_C PF10479.9 EJP64957.1 - 4.3 5.3 7.8 6.9 4.7 7.8 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SUR7 PF06687.12 EJP64958.1 - 5.3e-29 101.4 15.0 6.6e-29 101.1 15.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family zf-PHD-like PF15446.6 EJP64962.1 - 5e-66 221.5 12.2 4.2e-65 218.5 10.7 2.3 1 1 1 2 2 2 2 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 EJP64962.1 - 1.3e-47 162.3 0.0 2.3e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP64962.1 - 4.3e-18 65.7 0.0 1.1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EJP64962.1 - 8.9e-10 38.2 0.8 1.8e-09 37.2 0.8 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 EJP64962.1 - 1.8e-07 31.0 17.9 0.0002 21.2 9.1 2.8 2 1 0 2 2 2 2 PHD-finger ResIII PF04851.15 EJP64962.1 - 3.4e-05 23.9 0.0 0.00031 20.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 EJP64962.1 - 0.00012 21.9 1.4 0.00073 19.4 1.3 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.6 EJP64962.1 - 0.0013 18.2 0.2 0.0013 18.2 0.2 3.0 2 1 0 2 2 1 1 PHD-finger zf-RING_11 PF17123.5 EJP64962.1 - 0.11 12.3 3.9 0.24 11.2 3.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger Cript PF10235.9 EJP64962.1 - 0.11 13.1 0.4 0.55 10.8 0.1 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT C1_1 PF00130.22 EJP64962.1 - 0.16 11.8 14.6 0.05 13.5 3.9 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ_CXXCXGXG PF00684.19 EJP64962.1 - 2.7 8.4 6.9 8.8 6.8 1.1 2.8 2 0 0 2 2 2 0 DnaJ central domain PHD_4 PF16866.5 EJP64962.1 - 8.6 6.5 12.4 4.6 7.4 2.0 3.0 2 0 0 2 2 2 0 PHD-finger SpoU_methylase PF00588.19 EJP64963.1 - 7.8e-24 84.5 0.0 1.9e-23 83.2 0.0 1.6 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EJP64963.1 - 3.1e-09 37.0 0.0 6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Phasin_2 PF09361.10 EJP64964.1 - 0.18 12.1 0.8 0.36 11.1 0.8 1.5 1 1 0 1 1 1 0 Phasin protein COX14 PF14880.6 EJP64965.1 - 0.16 11.8 1.2 0.5 10.2 0.1 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Fungal_trans PF04082.18 EJP64966.1 - 2.2e-16 59.7 0.5 3.9e-16 58.9 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EJP64966.1 - 2.1e-05 24.7 19.4 0.0016 18.8 1.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP64966.1 - 0.2 12.6 17.2 0.17 12.8 2.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP64966.1 - 2.3 8.6 4.3 2.3 8.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CTP_transf_like PF01467.26 EJP64967.1 - 2.3e-30 105.6 0.0 4.9e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like PS_Dcarbxylase PF02666.15 EJP64968.1 - 3.8e-56 189.8 0.0 7.5e-56 188.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EJP64968.1 - 3.2e-37 127.0 0.0 3.2e-17 62.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.6 EJP64968.1 - 0.0021 17.5 0.0 0.0059 16.0 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EJP64968.1 - 0.0071 15.8 0.0 0.024 14.2 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EJP64968.1 - 0.02 14.8 0.1 0.3 11.1 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EJP64968.1 - 0.1 13.1 3.0 0.27 11.7 0.3 2.6 2 0 0 2 2 2 0 EF-hand domain pair Transposase_28 PF04195.12 EJP64969.1 - 0.037 14.2 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative gypsy type transposon Ribosomal_L5e PF17144.4 EJP64970.1 - 6e-79 263.7 0.2 9.3e-79 263.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EJP64970.1 - 7.3e-34 116.6 7.8 7.3e-34 116.6 7.8 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DAG_kinase_N PF14513.6 EJP64970.1 - 0.031 14.5 0.9 0.053 13.7 0.9 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Thr_synth_N PF14821.6 EJP64970.1 - 0.13 12.5 0.2 21 5.4 0.0 2.8 2 1 0 2 2 2 0 Threonine synthase N terminus HAD_2 PF13419.6 EJP64971.1 - 6.2e-05 23.2 0.0 0.00011 22.3 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP64971.1 - 0.042 14.1 0.1 0.072 13.4 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP64971.1 - 0.079 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF913 PF06025.12 EJP64971.1 - 0.14 11.1 0.0 0.36 9.7 0.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DHquinase_I PF01487.15 EJP64972.1 - 9.7e-41 140.5 0.0 1.5e-40 139.9 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.18 EJP64973.1 - 3e-16 59.2 0.0 5.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64973.1 - 1.9e-05 24.7 15.5 3.6e-05 23.8 15.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EJP64974.1 - 3.2e-26 92.1 51.0 6.9e-26 91.0 51.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP64974.1 - 2e-06 27.0 14.8 2e-06 27.0 14.8 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP64975.1 - 9.8e-10 37.9 39.4 1.8e-08 33.7 18.0 4.3 2 2 1 3 3 3 2 Major Facilitator Superfamily ESSS PF10183.9 EJP64975.1 - 0.12 12.6 1.3 1.4 9.2 0.0 3.2 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MSP1a PF11670.8 EJP64975.1 - 0.35 10.1 4.7 0.24 10.7 0.7 2.4 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) NAD_binding_6 PF08030.12 EJP64976.1 - 2.1e-18 66.9 0.0 3.2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EJP64976.1 - 8.4e-15 55.0 16.8 8.4e-15 55.0 16.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EJP64976.1 - 2.4e-08 34.0 0.1 9.4e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EJP64976.1 - 0.1 13.3 0.0 2.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain RTA1 PF04479.13 EJP64977.1 - 1.3e-18 67.4 4.3 1.9e-18 66.9 4.3 1.3 1 0 0 1 1 1 1 RTA1 like protein LCE6A PF15858.5 EJP64977.1 - 0.0072 17.1 4.3 0.015 16.1 4.3 1.5 1 0 0 1 1 1 1 Late cornified envelope protein 6A family Arrestin_N PF00339.29 EJP64978.1 - 2.1e-13 50.6 0.0 3.9e-09 36.7 0.0 3.3 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF4899 PF16240.5 EJP64978.1 - 0.089 12.0 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4899) Bul1_C PF04426.12 EJP64978.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus Abhydrolase_6 PF12697.7 EJP64979.1 - 2.5e-06 28.3 4.2 4e-06 27.6 4.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EJP64979.1 - 8.2e-06 25.7 0.1 2e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EJP64979.1 - 4.1e-05 23.6 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EJP64979.1 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EJP64979.1 - 0.00061 19.5 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 EJP64979.1 - 0.0063 15.7 0.0 0.009 15.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase LapA_dom PF06305.11 EJP64980.1 - 0.015 15.1 0.1 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MFS_MOT1 PF16983.5 EJP64981.1 - 1.6e-60 202.4 31.9 9.5e-34 116.1 10.8 2.9 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily MASE1 PF05231.14 EJP64982.1 - 0.027 13.6 6.7 0.082 12.0 6.7 1.7 1 1 0 1 1 1 0 MASE1 DHHC PF01529.20 EJP64982.1 - 0.038 14.1 0.9 0.038 14.1 0.9 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF2207 PF09972.9 EJP64982.1 - 0.28 9.9 1.1 0.38 9.5 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Forkhead PF00250.18 EJP64983.1 - 2e-14 53.6 0.0 4.1e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EJP64983.1 - 0.00019 21.7 0.0 0.0004 20.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain SH3_9 PF14604.6 EJP64984.1 - 3.7e-13 49.1 0.0 7.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EJP64984.1 - 1.7e-11 43.6 0.0 3.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 EJP64984.1 - 1.8e-11 43.9 0.1 6.5e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 EJP64984.1 - 9e-10 39.0 0.0 2.6e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EJP64984.1 - 0.00037 20.9 0.1 0.00088 19.7 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 EJP64984.1 - 0.00052 19.6 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 EJP64984.1 - 0.0036 17.6 0.0 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.30 EJP64984.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-MIZ PF02891.20 EJP64985.1 - 4.1e-08 32.8 5.9 1.1e-07 31.5 5.9 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EJP64985.1 - 0.073 12.9 1.1 0.17 11.7 1.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SHNi-TPR PF10516.9 EJP64987.1 - 5.9e-14 51.2 0.9 3.3e-13 48.9 0.0 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 EJP64987.1 - 0.0018 18.3 7.5 0.019 15.1 0.7 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP64987.1 - 0.0023 18.2 6.7 0.0044 17.3 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP64987.1 - 0.011 16.3 6.3 0.018 15.7 0.8 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 EJP64987.1 - 0.035 14.1 0.4 0.035 14.1 0.4 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EJP64987.1 - 0.046 13.4 3.7 0.51 10.1 0.2 3.4 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.28 EJP64987.1 - 0.057 13.3 0.3 0.8 9.6 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP64987.1 - 0.67 10.9 2.4 2.1 9.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Mpp10 PF04006.12 EJP64988.1 - 2.5e-104 350.0 52.3 3e-103 346.4 52.3 2.0 1 1 0 1 1 1 1 Mpp10 protein zf-C3HC4 PF00097.25 EJP64989.1 - 3.5e-07 30.0 5.6 6.4e-07 29.1 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP64989.1 - 2.9e-06 27.0 4.8 6.7e-06 25.9 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP64989.1 - 4.5e-06 26.6 3.2 4.5e-06 26.6 1.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EJP64989.1 - 8.3e-06 26.0 5.7 1.8e-05 25.0 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EJP64989.1 - 1.9e-05 24.5 4.0 4e-05 23.5 4.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EJP64989.1 - 3.1e-05 24.1 2.8 6.9e-05 22.9 2.8 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EJP64989.1 - 5.7e-05 22.9 6.3 0.00013 21.8 2.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJP64989.1 - 0.0029 17.4 5.1 0.022 14.6 5.2 2.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EJP64989.1 - 0.24 11.7 5.9 0.13 12.6 2.8 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EJP64989.1 - 0.33 11.1 4.8 0.9 9.7 4.8 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 TerY_C PF15616.6 EJP64989.1 - 0.85 9.7 2.5 2.7 8.1 2.5 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain Lar_restr_allev PF14354.6 EJP64989.1 - 7.1 7.1 6.8 3.8 8.0 1.2 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar Actin PF00022.19 EJP64990.1 - 6.8e-86 288.4 0.0 9.8e-52 175.9 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 EJP64990.1 - 0.01 14.7 0.1 2.4 6.9 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein ADH_N PF08240.12 EJP64991.1 - 1.2e-27 95.9 1.6 1.2e-27 95.9 1.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP64991.1 - 2.2e-22 79.4 0.0 4.1e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP64991.1 - 0.0009 20.3 0.0 0.0016 19.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EJP64991.1 - 0.0019 17.5 0.4 0.0028 17.0 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EJP64991.1 - 0.037 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 EJP64991.1 - 0.054 12.9 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase HMA PF00403.26 EJP64992.1 - 9.5e-16 58.0 1.9 3.6e-15 56.2 0.3 1.9 1 1 1 2 2 2 1 Heavy-metal-associated domain PIEZO PF15917.5 EJP64993.1 - 0.0092 15.5 0.9 0.025 14.1 0.9 1.7 1 0 0 1 1 1 1 Piezo SpoIIIAH PF12685.7 EJP64993.1 - 0.079 12.8 6.0 1.4 8.7 0.6 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Band_3_cyto PF07565.13 EJP64993.1 - 0.12 12.2 2.0 5.2 6.8 0.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4746 PF15928.5 EJP64993.1 - 1.3 8.4 11.8 0.47 9.8 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) BUD22 PF09073.10 EJP64993.1 - 4 6.7 29.3 0.036 13.4 3.6 2.3 2 0 0 2 2 2 0 BUD22 Vfa1 PF08432.10 EJP64993.1 - 4.1 7.7 12.8 1.8 8.8 5.1 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1168 PF06658.12 EJP64993.1 - 7.6 6.4 18.3 0.19 11.5 8.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Thiolase_N PF00108.23 EJP64994.1 - 3.7e-16 59.3 0.0 1.4e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EJP64994.1 - 1.6e-12 47.2 0.2 1.6e-12 47.2 0.2 2.4 3 1 1 4 4 4 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EJP64994.1 - 5.8e-06 26.1 0.5 0.0004 20.2 0.5 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 EJP64994.1 - 0.00037 20.5 1.8 0.58 10.2 0.0 3.5 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EJP64994.1 - 0.012 15.2 0.2 0.029 14.0 0.1 1.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EJP64994.1 - 0.079 11.6 1.8 0.4 9.3 0.2 2.3 3 0 0 3 3 3 0 Stage V sporulation protein AD (SpoVAD) Endotoxin_N PF03945.14 EJP64995.1 - 3.6e-19 69.4 0.0 2.7e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain Fungal_trans PF04082.18 EJP64996.1 - 1e-15 57.5 0.2 1.6e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP64996.1 - 1.2e-06 28.5 16.7 2e-06 27.8 16.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tcf25 PF04910.14 EJP64997.1 - 8.6e-59 199.4 0.0 1.3e-58 198.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 AP3D1 PF06375.11 EJP64997.1 - 3.5 7.9 20.9 0.036 14.3 6.4 3.1 4 0 0 4 4 4 0 AP-3 complex subunit delta-1 Nop53 PF07767.11 EJP64997.1 - 8.1 5.7 31.0 0.17 11.3 20.5 2.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) LSM14 PF12701.7 EJP64998.1 - 2.4e-32 110.9 0.1 4e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EJP64998.1 - 2.8e-14 53.9 13.3 4.2e-13 50.1 13.3 2.3 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.6 EJP64998.1 - 6.7e-06 26.2 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain V-SNARE PF05008.15 EJP64999.1 - 3.3e-21 75.4 1.9 3.3e-21 75.4 1.9 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EJP64999.1 - 2.6e-17 62.8 1.6 2.6e-17 62.8 1.6 3.2 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Laminin_I PF06008.14 EJP64999.1 - 0.017 14.8 3.1 0.035 13.8 0.4 2.1 2 0 0 2 2 2 0 Laminin Domain I FAM219A PF15260.6 EJP64999.1 - 0.041 14.2 0.8 0.041 14.2 0.8 1.8 2 0 0 2 2 2 0 Protein family FAM219A FAM76 PF16046.5 EJP64999.1 - 0.51 9.6 1.6 0.36 10.1 0.1 1.4 2 0 0 2 2 2 0 FAM76 protein YqjK PF13997.6 EJP64999.1 - 6.5 7.1 6.6 8.4 6.7 0.4 2.7 3 0 0 3 3 3 0 YqjK-like protein Amino_oxidase PF01593.24 EJP65000.1 - 1e-22 81.1 0.3 4.4e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP65000.1 - 1.1e-10 41.5 0.1 2.6e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EJP65000.1 - 3.1e-06 27.3 0.0 0.051 13.6 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EJP65000.1 - 0.0003 20.1 0.0 0.048 12.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP65000.1 - 0.00032 20.4 1.3 0.012 15.2 0.1 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP65000.1 - 0.0053 15.5 0.0 1.7 7.2 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Syja_N PF02383.18 EJP65000.1 - 0.044 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 SacI homology domain Pyr_redox PF00070.27 EJP65000.1 - 0.052 14.1 0.0 0.5 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP65000.1 - 0.13 11.3 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EJP65000.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP65000.1 - 0.16 11.1 0.1 0.3 10.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain CtaG_Cox11 PF04442.14 EJP65001.1 - 6.8e-60 201.5 0.1 3.5e-59 199.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Ribosomal_L26 PF16906.5 EJP65002.1 - 5.8e-38 129.2 1.8 7.7e-38 128.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EJP65002.1 - 5.2e-07 29.4 0.5 1.3e-06 28.1 0.5 1.7 1 0 0 1 1 1 1 KOW motif GHL5 PF14872.6 EJP65002.1 - 0.032 12.3 0.0 0.037 12.1 0.0 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 DUF1223 PF06764.11 EJP65002.1 - 0.078 13.0 0.1 0.13 12.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) DUF3546 PF12066.8 EJP65003.1 - 0.028 14.6 2.5 0.11 12.7 3.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) Hs1pro-1_C PF07014.12 EJP65003.1 - 0.063 12.7 0.3 0.1 12.1 0.3 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus DUF4337 PF14235.6 EJP65003.1 - 0.76 9.9 3.4 1.5 8.9 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FlxA PF14282.6 EJP65003.1 - 2.1 8.4 6.9 0.24 11.4 1.6 2.1 2 0 0 2 2 2 0 FlxA-like protein SET PF00856.28 EJP65004.1 - 0.0056 17.1 0.0 0.038 14.4 0.0 2.0 2 0 0 2 2 2 1 SET domain PARP PF00644.20 EJP65006.1 - 3.9e-11 42.9 0.0 8.3e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 EJP65006.1 - 1.9e-09 37.3 0.0 1.7e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP65006.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B SHIRT PF18655.1 EJP65006.1 - 0.17 12.5 0.1 0.38 11.4 0.1 1.6 1 0 0 1 1 1 0 SHIRT domain Pribosyl_synth PF14572.6 EJP65007.1 - 3.5e-42 144.5 1.2 9.5e-37 126.8 0.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EJP65007.1 - 1.4e-30 105.6 0.0 3.2e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EJP65007.1 - 1e-14 54.4 0.2 2.1e-14 53.4 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RNA_pol_Rpb4 PF03874.16 EJP65008.1 - 3.5e-24 85.5 0.1 4.1e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 GatB_Yqey PF02637.18 EJP65008.1 - 0.055 13.3 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 GatB domain Ras PF00071.22 EJP65009.1 - 5.9e-20 71.5 0.0 8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP65009.1 - 1.4e-05 25.3 0.0 4.6e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP65009.1 - 3.6e-05 23.3 0.0 0.00015 21.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 EJP65009.1 - 0.018 14.7 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EJP65009.1 - 0.025 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.6 EJP65009.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PseudoU_synth_1 PF01416.20 EJP65010.1 - 6.4e-33 113.5 0.0 5.5e-32 110.4 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase Catalase PF00199.19 EJP65011.1 - 1.7e-171 570.6 0.1 2.2e-171 570.1 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EJP65011.1 - 4.6e-18 65.2 0.1 9.4e-18 64.2 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EJP65011.1 - 4.8e-13 49.0 0.9 1.5e-12 47.4 0.5 2.0 2 1 0 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EJP65011.1 - 1.1e-08 35.1 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Acetyltransf_1 PF00583.25 EJP65013.1 - 2e-08 34.5 0.0 2.9e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP65013.1 - 0.00012 22.5 0.0 0.00032 21.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP65013.1 - 0.0045 16.9 0.0 1.4 8.8 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EJP65013.1 - 0.13 12.9 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RRM_1 PF00076.22 EJP65014.1 - 3.7e-16 58.7 0.0 4.3e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP65014.1 - 0.00049 20.2 0.0 0.00054 20.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 EJP65014.1 - 0.034 14.2 0.0 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif E1-E2_ATPase PF00122.20 EJP65015.1 - 2e-34 118.7 17.2 7.4e-29 100.6 0.4 3.7 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EJP65015.1 - 2e-28 99.3 12.1 2e-28 99.3 12.1 2.8 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EJP65015.1 - 1.6e-20 74.3 0.0 5.7e-19 69.2 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJP65015.1 - 1.5e-17 63.5 0.0 3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EJP65015.1 - 2e-12 46.6 0.0 5.7e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP65015.1 - 6e-05 22.9 0.4 0.00022 21.1 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SET PF00856.28 EJP65016.1 - 2.4e-17 63.8 0.0 4.8e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EJP65016.1 - 5.9e-10 39.9 0.2 2e-08 35.0 0.1 2.9 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding Adap_comp_sub PF00928.21 EJP65017.1 - 1.5e-90 303.1 0.0 2.7e-90 302.3 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EJP65017.1 - 3.9e-08 33.3 0.2 6.2e-08 32.7 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EJP65017.1 - 0.17 11.3 0.0 0.65 9.4 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Opi1 PF08618.10 EJP65018.1 - 7.8e-38 130.8 28.7 6e-29 101.5 2.5 4.8 4 1 1 5 5 5 3 Transcription factor Opi1 SMG1 PF15785.5 EJP65018.1 - 0.087 11.2 0.4 0.12 10.8 0.4 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 PPP4R2 PF09184.11 EJP65019.1 - 8.4 5.9 13.3 33 3.9 13.3 1.7 1 1 0 1 1 1 0 PPP4R2 Ank_2 PF12796.7 EJP65020.1 - 4.7e-47 158.5 6.7 1.6e-07 31.8 0.1 6.6 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP65020.1 - 9.1e-40 134.6 6.0 3.4e-06 27.5 0.0 10.1 4 4 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP65020.1 - 3.8e-32 106.7 5.5 0.028 14.9 0.0 13.0 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 EJP65020.1 - 2.1e-23 82.1 8.6 2.8e-05 24.3 0.1 7.8 3 2 7 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 EJP65020.1 - 1.3e-19 69.7 16.8 0.013 16.0 0.0 12.0 11 2 0 11 11 11 3 Ankyrin repeat SesA PF17107.5 EJP65020.1 - 1e-12 48.3 0.0 2.7e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 EJP65020.1 - 0.00085 19.7 0.3 0.012 16.0 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EJP65020.1 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 EJP65020.1 - 0.015 14.6 0.0 0.048 12.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin FAD_binding_3 PF01494.19 EJP65021.1 - 2.3e-74 250.7 0.9 1.1e-73 248.5 0.9 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EJP65021.1 - 2.6e-05 24.7 0.5 0.0049 17.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP65021.1 - 4.7e-05 23.5 1.3 0.00047 20.3 0.9 3.0 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP65021.1 - 7.3e-05 22.1 0.3 0.00045 19.5 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP65021.1 - 0.00023 20.9 7.0 0.00034 20.3 2.2 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EJP65021.1 - 0.00026 20.4 0.1 0.00042 19.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EJP65021.1 - 0.00072 18.7 0.2 0.0046 16.1 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein XdhC_C PF13478.6 EJP65021.1 - 0.00097 19.6 0.3 0.0026 18.3 0.1 1.8 2 0 0 2 2 1 1 XdhC Rossmann domain HI0933_like PF03486.14 EJP65021.1 - 0.002 16.9 0.1 0.0033 16.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EJP65021.1 - 0.0073 15.6 0.2 0.014 14.7 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EJP65021.1 - 0.011 14.9 2.2 0.014 14.5 1.2 1.7 2 0 0 2 2 2 0 FAD binding domain CAP_N PF01213.19 EJP65021.1 - 0.064 12.7 3.3 0.096 12.2 3.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SE PF08491.10 EJP65021.1 - 0.15 11.1 0.0 0.4 9.7 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase K_oxygenase PF13434.6 EJP65021.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DEC-1_N PF04625.13 EJP65021.1 - 0.17 10.9 1.2 0.23 10.5 1.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AlaDh_PNT_C PF01262.21 EJP65021.1 - 0.35 10.1 1.7 0.68 9.2 1.6 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EJP65021.1 - 0.38 9.8 1.2 1.2 8.2 2.0 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Mito_fiss_reg PF05308.11 EJP65021.1 - 0.83 9.7 3.2 1.3 9.1 3.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase PF00069.25 EJP65022.1 - 7.5e-09 35.3 0.0 6.1e-08 32.4 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain APH PF01636.23 EJP65022.1 - 4.6e-05 23.4 0.8 0.00011 22.2 0.8 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EJP65022.1 - 0.00033 20.0 0.0 0.00068 19.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP65022.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJP65022.1 - 0.025 13.9 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RGS12_usC PF16612.5 EJP65023.1 - 0.024 15.1 0.4 0.032 14.7 0.4 1.2 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 Amidohydro_1 PF01979.20 EJP65024.1 - 2e-42 145.8 0.1 2.4e-42 145.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EJP65024.1 - 2.8e-17 63.3 1.8 2.1e-11 44.0 0.1 2.4 1 1 0 2 2 2 2 Amidohydrolase family Fungal_trans PF04082.18 EJP65025.1 - 1.7e-16 60.1 0.5 3.2e-16 59.2 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65025.1 - 0.00046 20.3 6.9 0.00084 19.4 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IPP-2 PF04979.14 EJP65027.1 - 4.9e-19 69.4 14.8 4.9e-19 69.4 14.8 2.3 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Baculo_VP91_N PF08475.10 EJP65028.1 - 0.13 11.9 0.1 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Ribosomal_L27 PF01016.19 EJP65029.1 - 2.7e-26 91.4 0.1 7e-26 90.1 0.1 1.8 1 0 0 1 1 1 1 Ribosomal L27 protein PCNP PF15473.6 EJP65029.1 - 0.51 11.1 5.1 1.1 10.0 5.1 1.5 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family CorA PF01544.18 EJP65030.1 - 1.6e-10 40.8 4.7 3.2e-10 39.8 3.7 2.0 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 EJP65030.1 - 0.00034 20.2 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EJP65030.1 - 0.024 13.9 0.0 0.06 12.6 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP65030.1 - 0.15 12.7 0.1 0.15 12.7 0.1 2.3 2 1 1 3 3 3 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EJP65030.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Vps62 PF06101.11 EJP65031.1 - 0.072 11.4 0.5 0.65 8.2 0.2 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 62 ETX_MTX2 PF03318.13 EJP65032.1 - 0.0029 17.4 13.3 0.0045 16.8 13.3 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 NIF PF03031.18 EJP65035.1 - 3.9e-43 146.9 0.1 5.7e-43 146.4 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DotU PF09850.9 EJP65035.1 - 0.057 13.1 0.0 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 Type VI secretion system protein DotU Sigma70_r4 PF04545.16 EJP65036.1 - 0.041 13.4 0.0 13 5.4 0.1 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 Vta1 PF04652.16 EJP65037.1 - 4.3e-50 169.5 1.3 4.3e-50 169.5 1.3 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EJP65037.1 - 5.9e-18 64.3 0.1 1.3e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain HsbA PF12296.8 EJP65038.1 - 2.9e-21 76.1 9.1 2.9e-21 76.1 9.1 2.5 2 1 0 2 2 2 1 Hydrophobic surface binding protein A Syntaxin_2 PF14523.6 EJP65038.1 - 0.00042 20.6 2.7 0.011 16.0 0.7 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SAPIS-gp6 PF16722.5 EJP65038.1 - 0.074 13.5 1.5 1 9.8 0.2 2.5 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Apolipoprotein PF01442.18 EJP65038.1 - 0.11 12.4 3.5 0.27 11.1 3.5 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain MRP-S31 PF15433.6 EJP65038.1 - 1.4 8.6 5.1 0.73 9.5 1.3 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 MFS_1 PF07690.16 EJP65039.1 - 1.6e-36 126.0 39.0 1.6e-36 126.0 39.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EJP65039.1 - 0.0017 17.7 6.9 0.0017 17.7 6.9 2.7 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Rick_17kDa_Anti PF05433.15 EJP65039.1 - 0.083 12.8 0.7 0.19 11.6 0.7 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain ANAPC4_WD40 PF12894.7 EJP65040.1 - 1.7e-05 25.0 0.1 0.38 11.1 0.1 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SBP56 PF05694.11 EJP65040.1 - 0.017 13.9 0.0 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 56kDa selenium binding protein (SBP56) PQQ_3 PF13570.6 EJP65040.1 - 0.038 14.5 0.1 0.15 12.6 0.1 2.2 1 0 0 1 1 1 0 PQQ-like domain WD40 PF00400.32 EJP65040.1 - 0.22 12.4 5.7 1.8 9.6 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat TIP120 PF08623.10 EJP65041.1 - 2.7e-74 248.5 3.4 6.5e-70 234.3 0.0 4.3 3 1 1 4 4 4 2 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EJP65041.1 - 7.6e-14 50.6 22.6 0.52 10.7 0.2 12.4 12 1 1 13 13 13 4 HEAT repeat HEAT_2 PF13646.6 EJP65041.1 - 5.6e-13 49.1 27.4 0.041 14.3 2.2 9.0 9 2 1 10 10 8 5 HEAT repeats Vac14_Fab1_bd PF12755.7 EJP65041.1 - 5.3e-06 26.9 0.9 0.97 10.1 0.0 6.4 6 1 1 7 7 6 2 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EJP65041.1 - 5.2e-05 23.4 17.7 0.19 11.9 0.1 7.0 8 1 0 8 8 8 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EJP65041.1 - 0.00028 21.0 23.3 0.0077 16.3 0.8 6.9 6 1 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 EJP65041.1 - 0.0003 19.2 12.2 0.00086 17.7 1.1 4.5 4 3 0 4 4 4 2 Down-regulated in metastasis VHS PF00790.19 EJP65041.1 - 0.0023 17.8 0.3 0.81 9.5 0.0 3.7 3 0 0 3 3 3 1 VHS domain DUF3510 PF12022.8 EJP65041.1 - 0.06 13.7 1.2 0.36 11.2 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) Cnd3 PF12719.7 EJP65041.1 - 0.061 12.5 2.5 3.7 6.7 0.0 4.3 4 2 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF3361 PF11841.8 EJP65041.1 - 0.074 13.0 12.2 4.6 7.2 0.0 5.9 4 2 2 6 6 6 0 Domain of unknown function (DUF3361) RICTOR_N PF14664.6 EJP65041.1 - 0.11 11.4 0.0 0.11 11.4 0.0 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 EJP65041.1 - 0.34 11.3 2.2 7.2 7.1 0.0 4.3 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Sigma70_ner PF04546.13 EJP65041.1 - 3.9 7.3 9.2 20 5.0 5.0 2.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Sugar_tr PF00083.24 EJP65042.1 - 7.9e-121 404.1 7.2 1.4e-120 403.3 7.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP65042.1 - 1.1e-22 80.5 46.4 9.3e-14 51.1 21.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.25 EJP65043.1 - 2e-56 191.6 0.3 3.3e-56 190.8 0.3 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 EJP65043.1 - 1.1e-26 93.8 0.1 1.8e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJP65043.1 - 6.1e-16 58.3 0.0 1.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EJP65043.1 - 0.0078 15.9 0.3 0.023 14.4 0.2 1.8 2 0 0 2 2 2 1 Peptidase family M28 Homeobox_KN PF05920.11 EJP65044.1 - 1.8e-17 63.0 0.1 4.7e-17 61.6 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EJP65044.1 - 2.5e-10 40.0 0.1 5e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Homeodomain zf-met PF12874.7 EJP65044.1 - 0.0046 17.3 9.5 0.0051 17.2 0.6 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type HTH_36 PF13730.6 EJP65044.1 - 0.02 14.9 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain COX17 PF05051.13 EJP65044.1 - 0.23 11.8 1.5 0.7 10.3 1.5 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) zf-C2H2_2 PF12756.7 EJP65044.1 - 0.24 11.7 11.5 18 5.7 8.4 3.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EJP65044.1 - 7.4 7.2 26.2 0.059 13.8 1.8 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type Methyltransf_24 PF13578.6 EJP65045.1 - 2.1e-12 48.0 0.1 3.9e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EJP65045.1 - 3.9e-05 22.9 0.0 5.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Ribosomal_60s PF00428.19 EJP65045.1 - 0.23 12.1 2.3 0.35 11.5 2.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein MFS_1 PF07690.16 EJP65046.1 - 1.6e-13 50.3 39.6 1.6e-13 50.3 39.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP65046.1 - 2.1e-05 23.1 26.1 3.9e-05 22.3 26.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cwf_Cwc_15 PF04889.12 EJP65046.1 - 0.0016 18.3 6.5 0.0025 17.6 6.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3245 PF11595.8 EJP65046.1 - 0.047 14.2 2.0 0.082 13.4 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) FYDLN_acid PF09538.10 EJP65046.1 - 0.074 13.7 6.4 0.13 12.9 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Slu7 PF11708.8 EJP65046.1 - 0.48 10.1 5.8 0.71 9.6 5.8 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor FUN14 PF04930.15 EJP65046.1 - 0.78 10.2 0.0 0.78 10.2 0.0 3.4 4 1 0 4 4 4 0 FUN14 family NOA36 PF06524.12 EJP65046.1 - 1 8.6 4.7 1.5 8.1 4.7 1.1 1 0 0 1 1 1 0 NOA36 protein PGA2 PF07543.12 EJP65046.1 - 1.8 8.6 7.4 3.1 7.8 7.4 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 ADH_zinc_N_2 PF13602.6 EJP65047.1 - 4.1e-14 53.8 0.0 7.9e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EJP65047.1 - 6.5e-11 42.3 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EJP65047.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) SNF PF00209.18 EJP65048.1 - 8.6e-79 265.6 33.9 4.7e-78 263.1 33.8 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Fe-S_biosyn PF01521.20 EJP65049.1 - 2.2e-19 69.7 0.0 1e-18 67.5 0.0 1.8 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis DUF4707 PF15806.5 EJP65049.1 - 0.55 9.1 5.5 0.76 8.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) Ndc1_Nup PF09531.10 EJP65049.1 - 0.65 8.6 3.8 0.68 8.6 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fungal_trans_2 PF11951.8 EJP65050.1 - 6.4e-18 64.7 0.2 1.4e-17 63.6 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65050.1 - 3e-06 27.2 7.7 6.3e-06 26.2 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rab15_effector PF15208.6 EJP65050.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Rab15 effector GFO_IDH_MocA PF01408.22 EJP65051.1 - 7.1e-27 94.6 0.1 1.1e-26 94.0 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EJP65051.1 - 1.2e-11 44.6 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EJP65051.1 - 7.2e-06 26.7 0.0 1.6e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EJP65051.1 - 3.8e-05 24.1 0.0 8.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EJP65051.1 - 0.0024 18.0 0.1 0.0053 16.9 0.0 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 EJP65051.1 - 0.0079 16.9 0.4 0.017 15.8 0.1 1.7 2 0 0 2 2 2 1 CoA binding domain Sacchrp_dh_NADP PF03435.18 EJP65051.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peripla_BP_6 PF13458.6 EJP65051.1 - 0.012 15.3 0.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein OCD_Mu_crystall PF02423.15 EJP65051.1 - 0.079 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family CoA_binding_2 PF13380.6 EJP65051.1 - 0.15 12.6 0.1 0.27 11.7 0.1 1.3 1 0 0 1 1 1 0 CoA binding domain MFS_1 PF07690.16 EJP65052.1 - 1.7e-25 89.7 29.4 4.7e-25 88.3 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_10 PF13460.6 EJP65053.1 - 7e-09 35.8 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding T2SSM_b PF10741.9 EJP65053.1 - 0.0048 16.7 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein M subtype b 4HBT_2 PF13279.6 EJP65054.1 - 1.1e-21 77.6 0.2 1.8e-21 76.9 0.2 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_hydro_16 PF00722.21 EJP65055.1 - 7.9e-15 54.8 1.4 1.1e-14 54.3 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EJP65055.1 - 0.0051 15.3 6.1 0.36 9.2 1.4 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 EJP65055.1 - 0.0053 16.4 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) adh_short PF00106.25 EJP65056.1 - 4.6e-35 120.9 0.1 5.8e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP65056.1 - 3.2e-24 85.8 0.0 4.2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP65056.1 - 6.3e-07 29.5 0.3 5.9e-06 26.3 0.3 2.3 2 1 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EJP65056.1 - 0.0018 18.3 0.2 0.0032 17.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 EJP65056.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 EJP65056.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) OKR_DC_1 PF01276.20 EJP65056.1 - 0.021 13.6 0.0 2.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain TrkA_N PF02254.18 EJP65056.1 - 0.025 14.9 0.1 0.16 12.3 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EJP65056.1 - 0.025 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EJP65056.1 - 0.046 13.2 0.1 0.089 12.2 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family HI0933_like PF03486.14 EJP65056.1 - 0.11 11.1 1.4 0.21 10.3 1.4 1.3 1 0 0 1 1 1 0 HI0933-like protein SEN1_N PF12726.7 EJP65056.1 - 0.13 10.5 0.1 8.1 4.5 0.0 2.0 1 1 1 2 2 2 0 SEN1 N terminal MFS_1 PF07690.16 EJP65057.1 - 3.6e-15 55.7 59.6 1.6e-11 43.7 38.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP65057.1 - 1.4e-08 33.6 26.6 2.2e-08 33.0 26.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EJP65057.1 - 0.00022 20.2 9.3 0.00022 20.2 9.3 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Pox_A14 PF05767.12 EJP65057.1 - 0.023 14.8 3.7 0.052 13.7 2.4 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Myb_DNA-bind_3 PF12776.7 EJP65058.1 - 4.2e-25 88.6 0.2 6.9e-25 87.9 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF5353 PF17304.2 EJP65059.1 - 1.7e-09 37.2 7.5 2.6e-09 36.7 7.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) DUF2397 PF09660.10 EJP65059.1 - 0.048 12.6 1.6 0.077 11.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Porin_5 PF16930.5 EJP65059.1 - 0.17 10.4 3.4 0.22 9.9 3.4 1.1 1 0 0 1 1 1 0 Putative porin CHCH PF06747.13 EJP65060.1 - 1.8e-05 24.7 5.9 3.1e-05 24.0 5.9 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EJP65060.1 - 0.099 13.1 1.8 0.22 12.0 1.8 1.6 1 0 0 1 1 1 0 GCK domain TPK_catalytic PF04263.16 EJP65061.1 - 3e-28 98.3 0.0 4.7e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EJP65061.1 - 1.1e-23 82.7 0.1 1.6e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain V-SNARE_C PF12352.8 EJP65062.1 - 8.9e-14 51.5 2.9 1.6e-13 50.7 0.2 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EJP65062.1 - 4.8e-05 23.2 0.1 0.0012 18.7 0.0 2.7 2 1 1 3 3 3 1 Sec20 Mito_fiss_reg PF05308.11 EJP65062.1 - 0.00017 21.8 2.1 0.0019 18.4 0.8 2.1 2 0 0 2 2 2 1 Mitochondrial fission regulator Sigma70_r4 PF04545.16 EJP65062.1 - 0.011 15.3 0.1 0.024 14.1 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 SurA_N_2 PF13623.6 EJP65062.1 - 0.075 12.9 0.1 0.075 12.9 0.1 2.0 2 0 0 2 2 2 0 SurA N-terminal domain KxDL PF10241.9 EJP65062.1 - 0.13 12.6 2.3 16 5.8 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein DivIC PF04977.15 EJP65062.1 - 0.34 10.7 5.2 4.3 7.2 0.1 3.3 2 1 0 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.12 EJP65062.1 - 2.1 8.4 11.2 0.94 9.5 3.6 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 EJP65062.1 - 3.3 7.4 7.6 9 6.0 2.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) MFS_1 PF07690.16 EJP65063.1 - 4.4e-50 170.6 23.0 4.4e-50 170.6 23.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP65063.1 - 2.5e-10 39.8 5.7 2.5e-10 39.8 5.7 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP65063.1 - 4.1e-08 32.1 5.3 6.1e-08 31.6 5.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EJP65063.1 - 0.25 9.7 15.3 0.013 13.9 9.4 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector CPP1-like PF11833.8 EJP65063.1 - 0.28 10.8 9.0 0.86 9.2 4.2 2.9 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like OATP PF03137.20 EJP65063.1 - 0.89 7.8 7.8 0.15 10.3 1.1 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family 7TM_GPCR_Srz PF10325.9 EJP65063.1 - 4.6 6.5 7.2 0.25 10.6 1.0 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz p450 PF00067.22 EJP65064.1 - 8.1e-49 166.6 0.0 8.5e-48 163.2 0.0 2.3 1 1 1 2 2 2 1 Cytochrome P450 PTR2 PF00854.21 EJP65065.1 - 1.3e-73 248.1 6.7 1.8e-73 247.6 6.7 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EJP65065.1 - 3.6e-05 22.9 23.9 3.6e-05 22.9 23.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Thymidylat_synt PF00303.19 EJP65066.1 - 2.9e-104 347.9 0.0 3.3e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Peptidase_M20 PF01546.28 EJP65067.1 - 9.3e-23 81.0 0.0 7.3e-22 78.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EJP65067.1 - 1.6e-15 57.2 5.0 0.0065 17.3 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Peptidase_M28 PF04389.17 EJP65067.1 - 2.7e-05 23.9 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 EJP65067.1 - 0.00025 20.9 0.0 0.00057 19.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 EJP65067.1 - 0.0023 18.2 0.0 9.5 6.6 0.0 3.9 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP65067.1 - 0.011 14.8 0.1 0.036 13.0 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M42 PF05343.14 EJP65067.1 - 0.054 12.5 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Glyco_hydro_2_C PF02836.17 EJP65068.1 - 1.8e-96 322.8 1.5 3.3e-96 322.0 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EJP65068.1 - 1.2e-59 201.9 0.1 2.3e-59 201.0 0.1 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EJP65068.1 - 8.1e-39 133.2 0.1 1.8e-38 132.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EJP65068.1 - 8.2e-23 80.7 0.0 3.9e-22 78.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EJP65068.1 - 1.4e-13 51.4 0.1 5.6e-13 49.5 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EJP65068.1 - 0.0061 17.1 0.1 0.025 15.2 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain MtrB PF05440.12 EJP65068.1 - 0.08 13.4 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B MFS_1 PF07690.16 EJP65069.1 - 3e-10 39.6 50.7 4e-09 35.9 31.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-CCHC_6 PF15288.6 EJP65070.1 - 9.5e-07 28.6 0.3 2.2e-06 27.4 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Reovirus_Mu2 PF07781.11 EJP65070.1 - 0.041 12.3 0.1 0.055 11.8 0.1 1.2 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 zf-C2H2_10 PF16588.5 EJP65070.1 - 0.11 12.2 1.1 0.22 11.3 1.1 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger ABC_membrane PF00664.23 EJP65071.1 - 2.2e-36 126.0 25.9 7.4e-26 91.4 8.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP65071.1 - 2.3e-20 73.5 0.0 4.9e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EJP65071.1 - 0.00033 20.6 0.1 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EJP65071.1 - 0.00043 20.7 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EJP65071.1 - 0.0018 18.0 0.1 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EJP65071.1 - 0.0035 16.8 0.1 2.4 7.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJP65071.1 - 0.0052 17.1 1.0 0.017 15.4 0.2 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EJP65071.1 - 0.026 13.6 0.1 0.053 12.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EJP65071.1 - 0.04 13.8 0.1 0.088 12.7 0.1 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 EJP65071.1 - 0.057 13.0 0.5 0.12 12.0 0.5 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EJP65071.1 - 0.088 13.3 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EJP65071.1 - 0.09 12.8 0.1 0.26 11.3 0.1 1.7 1 1 0 1 1 1 0 Dynamin family RecA PF00154.21 EJP65071.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein RsgA_GTPase PF03193.16 EJP65071.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Adeno_IVa2 PF02456.15 EJP65071.1 - 0.17 10.6 0.2 0.3 9.8 0.2 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein CAF-1_p150 PF11600.8 EJP65072.1 - 1.9 8.1 35.0 0.041 13.6 28.0 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Atg14 PF10186.9 EJP65072.1 - 3.7 6.5 13.0 5.6 6.0 13.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LUC7 PF03194.15 EJP65073.1 - 5.2e-67 226.2 2.5 6.4e-67 225.9 2.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 EJP65073.1 - 0.1 11.7 1.9 0.14 11.2 1.9 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) LPD11 PF18824.1 EJP65073.1 - 0.11 12.6 0.1 0.74 9.9 0.0 2.3 2 1 1 3 3 3 0 Large polyvalent protein-associated domain 11 FliJ PF02050.16 EJP65073.1 - 0.56 10.4 5.6 1.3 9.2 0.2 2.3 1 1 0 2 2 2 0 Flagellar FliJ protein Gpi16 PF04113.14 EJP65074.1 - 4.1e-238 791.4 0.0 5e-238 791.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Aminotran_3 PF00202.21 EJP65075.1 - 1.2e-89 300.9 0.0 1.4e-89 300.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EJP65075.1 - 0.0089 15.2 0.0 0.026 13.7 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II MFS_1 PF07690.16 EJP65076.1 - 9.8e-22 77.3 54.1 9.6e-15 54.3 30.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 EJP65076.1 - 7.4e-10 38.3 0.1 1.4e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.14 EJP65077.1 - 3.1e-49 167.8 5.3 4.2e-49 167.4 5.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1080 PF06439.11 EJP65077.1 - 0.00044 20.4 0.4 0.00088 19.4 0.4 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Glyco_hydro_130 PF04041.13 EJP65077.1 - 0.048 12.6 0.0 8.4 5.2 0.0 2.3 2 0 0 2 2 2 0 beta-1,4-mannooligosaccharide phosphorylase PIR PF00399.19 EJP65078.1 - 1.2e-33 113.9 75.9 3.2e-07 29.7 1.1 7.5 7 0 0 7 7 7 7 Yeast PIR protein repeat zf-U1 PF06220.12 EJP65079.1 - 7.4e-08 32.0 0.3 1.2e-07 31.4 0.3 1.3 1 0 0 1 1 1 1 U1 zinc finger TetR_C_6 PF13977.6 EJP65079.1 - 0.05 13.8 1.8 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal DLH PF01738.18 EJP65080.1 - 9.5e-26 90.7 0.1 1.2e-25 90.4 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF747 PF05346.11 EJP65081.1 - 7e-122 406.9 2.2 8.7e-122 406.6 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family HEAT_EZ PF13513.6 EJP65082.1 - 7.5e-19 67.8 5.4 3.8e-06 27.3 0.1 7.3 6 1 1 7 7 7 4 HEAT-like repeat HEAT PF02985.22 EJP65082.1 - 3.5e-16 57.9 1.0 0.12 12.7 0.1 8.8 8 0 0 8 8 7 3 HEAT repeat HEAT_2 PF13646.6 EJP65082.1 - 7.3e-13 48.7 10.3 0.0028 18.0 0.0 8.3 6 3 3 10 10 9 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EJP65082.1 - 4.3e-09 36.9 0.0 0.14 12.8 0.0 5.1 3 1 1 4 4 4 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EJP65082.1 - 1.3e-06 28.6 0.1 0.12 12.4 0.0 4.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 EJP65082.1 - 1.4e-06 28.2 0.0 0.13 12.0 0.0 4.3 5 0 0 5 5 5 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 EJP65082.1 - 2.8e-06 26.2 0.2 0.26 9.8 0.0 4.0 3 1 0 3 3 3 2 Adaptin N terminal region IFRD PF05004.13 EJP65082.1 - 3.4e-06 26.4 0.2 0.0069 15.5 0.2 4.1 3 1 0 3 3 3 2 Interferon-related developmental regulator (IFRD) Arm PF00514.23 EJP65082.1 - 0.00028 20.8 1.1 0.2 11.7 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EJP65082.1 - 0.00077 19.6 0.6 0.21 11.8 0.2 3.8 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EJP65082.1 - 0.017 14.7 0.0 2.6 7.5 0.0 3.7 5 0 0 5 5 5 0 CLASP N terminal LcrG PF07216.12 EJP65082.1 - 0.19 11.6 0.3 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 LcrG protein Importin_rep_4 PF18808.1 EJP65082.1 - 0.28 11.5 3.9 18 5.7 0.1 5.1 6 0 0 6 6 6 0 Importin repeat LysM PF01476.20 EJP65083.1 - 3.7e-12 46.1 0.0 5.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 LysM domain DUF903 PF06004.12 EJP65083.1 - 0.045 13.7 0.9 0.097 12.6 0.9 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) PLA2_B PF01735.18 EJP65084.1 - 8.8e-179 595.0 1.2 1.1e-178 594.7 1.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Fungal_trans_2 PF11951.8 EJP65085.1 - 9.1e-05 21.4 0.1 0.00013 20.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EJP65087.1 - 3.1e-43 147.5 0.1 4.7e-43 146.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP65087.1 - 3.7e-34 118.3 0.0 5.1e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP65087.1 - 8.9e-09 35.5 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EJP65087.1 - 6.2e-05 23.0 0.1 0.00013 21.9 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EJP65087.1 - 0.00012 21.6 0.1 0.00041 19.8 0.1 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EJP65087.1 - 0.00026 20.5 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 EJP65087.1 - 0.0012 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EJP65087.1 - 0.0018 18.5 0.0 0.006 16.8 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain NmrA PF05368.13 EJP65087.1 - 0.0036 16.9 0.1 0.0093 15.5 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 EJP65087.1 - 0.0086 16.6 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 EJP65087.1 - 0.011 15.7 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MGS PF02142.22 EJP65087.1 - 0.042 14.0 0.2 0.096 12.9 0.2 1.6 1 0 0 1 1 1 0 MGS-like domain Glyco_hydro_47 PF01532.20 EJP65088.1 - 4.5e-172 573.0 0.0 5.2e-172 572.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Nre_C PF04895.12 EJP65088.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Archaeal Nre, C-terminal SKG6 PF08693.10 EJP65089.1 - 3.7e-07 29.4 1.0 3.7e-07 29.4 1.0 2.2 2 0 0 2 2 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.6 EJP65089.1 - 0.0081 16.2 0.5 0.024 14.7 0.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) Gram_pos_anchor PF00746.21 EJP65089.1 - 0.094 12.7 0.5 0.094 12.7 0.5 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Plasmodium_Vir PF05795.11 EJP65089.1 - 0.57 9.5 4.7 0.87 8.9 4.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apt1 PF10351.9 EJP65089.1 - 1.1 8.0 7.5 1.6 7.5 7.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain AJAP1_PANP_C PF15298.6 EJP65089.1 - 1.3 9.2 19.5 0.7 10.1 17.3 1.6 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Macoilin PF09726.9 EJP65089.1 - 1.9 7.0 9.8 2.6 6.5 9.8 1.2 1 0 0 1 1 1 0 Macoilin family MAP65_ASE1 PF03999.12 EJP65089.1 - 5.4 5.6 6.9 6.5 5.3 6.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SSP160 PF06933.11 EJP65089.1 - 5.8 5.0 52.1 0.039 12.2 32.3 2.2 1 1 1 2 2 2 0 Special lobe-specific silk protein SSP160 GREB1 PF15782.5 EJP65089.1 - 6.6 3.7 9.4 7.7 3.5 9.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer QWRF PF04484.12 EJP65089.1 - 7.3 6.2 15.1 14 5.3 15.1 1.4 1 0 0 1 1 1 0 QWRF family Glyco_hydro_127 PF07944.12 EJP65090.1 - 3.2e-18 65.5 0.0 2.7e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 zf-C2H2_2 PF12756.7 EJP65091.1 - 6.6e-35 119.5 8.5 3.8e-29 101.0 0.4 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EJP65091.1 - 2.5e-07 30.8 22.0 2.5e-06 27.6 4.3 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJP65091.1 - 1e-05 25.8 9.4 1.4e-05 25.3 2.5 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SnoaL_2 PF12680.7 EJP65091.1 - 0.015 15.9 0.2 0.057 14.1 0.1 1.9 2 0 0 2 2 2 0 SnoaL-like domain zf-C2H2 PF00096.26 EJP65091.1 - 2.2 8.9 17.0 0.76 10.4 0.2 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type HNH_5 PF14279.6 EJP65091.1 - 8.3 6.4 6.4 25 4.8 0.3 3.6 4 0 0 4 4 4 0 HNH endonuclease HECT PF00632.25 EJP65092.1 - 2.5e-65 221.0 0.0 3.4e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EJP65092.1 - 1.2e-23 83.1 1.6 3.9e-23 81.4 1.6 2.0 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A 2OG-FeII_Oxy_2 PF13532.6 EJP65093.1 - 2.7e-30 106.0 0.0 3.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SSP160 PF06933.11 EJP65093.1 - 0.043 12.0 3.4 0.055 11.7 3.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cupin_3 PF05899.12 EJP65093.1 - 0.056 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF3439 PF11921.8 EJP65093.1 - 1.3 9.0 7.4 0.27 11.2 3.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) MMR_HSR1 PF01926.23 EJP65094.1 - 1.9e-14 53.7 0.0 3.3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJP65094.1 - 8.3e-06 25.5 0.0 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EJP65094.1 - 3.3e-05 24.0 0.0 0.0074 16.4 0.0 2.2 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EJP65094.1 - 0.00012 22.0 0.0 0.012 15.6 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 EJP65094.1 - 0.0019 17.7 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_29 PF13555.6 EJP65094.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EJP65094.1 - 0.067 12.5 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 EJP65094.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EJP65094.1 - 0.13 12.7 0.0 0.42 11.1 0.0 1.7 2 0 0 2 2 2 0 ABC transporter TniB PF05621.11 EJP65094.1 - 0.17 11.3 0.0 0.55 9.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AIG1 PF04548.16 EJP65094.1 - 0.18 11.1 0.0 8.2 5.7 0.0 2.1 2 0 0 2 2 2 0 AIG1 family Ndc1_Nup PF09531.10 EJP65094.1 - 2.5 6.7 4.4 5.9 5.5 2.0 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup zf-C3HC PF07967.13 EJP65095.1 - 5.9e-42 142.8 1.3 2.5e-35 121.4 0.6 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EJP65095.1 - 1.5e-26 92.4 3.2 8.5e-26 89.9 0.2 2.4 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.21 EJP65095.1 - 0.00038 21.1 0.1 0.081 13.6 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain SRP40_C PF05022.12 EJP65096.1 - 1e-17 64.7 0.5 4e-17 62.8 0.5 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain A_deaminase PF00962.22 EJP65097.1 - 1.7e-25 90.1 0.0 5.2e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase YcaO PF02624.16 EJP65097.1 - 0.084 12.1 0.7 0.14 11.4 0.7 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding PALP PF00291.25 EJP65098.1 - 1.5e-42 146.0 0.2 1.8e-42 145.8 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GARS_N PF02844.15 EJP65098.1 - 0.11 13.3 0.0 0.65 10.8 0.0 2.3 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain BLM10_mid PF16507.5 EJP65099.1 - 7.6e-194 645.2 0.0 1.1e-193 644.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EJP65099.1 - 8.3e-30 102.6 0.0 8.9e-29 99.3 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EJP65099.1 - 6.8e-20 71.2 0.1 1.6e-19 70.0 0.1 1.7 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 EJP65099.1 - 0.0032 17.6 0.5 9.4 6.8 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EJP65099.1 - 0.0071 16.4 0.1 0.73 9.9 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EJP65099.1 - 0.052 14.1 4.1 6.9 7.3 0.0 5.3 6 0 0 6 6 6 0 HEAT-like repeat Complex1_LYR PF05347.15 EJP65101.1 - 1.5e-09 37.8 0.0 3.2e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) bZIP_1 PF00170.21 EJP65102.1 - 2.3e-08 34.0 1.7 5.4e-08 32.8 1.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EJP65102.1 - 0.19 12.3 5.6 0.37 11.3 4.9 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 EJP65102.1 - 6.8 6.9 11.4 0.75 9.9 6.4 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Asparaginase_2 PF01112.18 EJP65103.1 - 2.1e-54 184.6 10.1 6.4e-28 97.7 0.6 5.0 4 1 0 4 4 4 4 Asparaginase Acetyltransf_1 PF00583.25 EJP65104.1 - 4.1e-11 43.1 0.0 7.6e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP65104.1 - 3.1e-08 33.6 0.0 4.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP65104.1 - 3.9e-06 27.2 0.0 6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP65104.1 - 0.0033 17.5 0.1 0.0047 17.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EJP65104.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase FR47 PF08445.10 EJP65104.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Sugar_tr PF00083.24 EJP65106.1 - 1.3e-31 109.9 26.7 1.4e-28 100.0 26.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP65106.1 - 1.3e-20 73.6 38.0 2.7e-14 52.9 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NMO PF03060.15 EJP65107.1 - 3.2e-48 164.8 0.6 5e-48 164.2 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EJP65107.1 - 1.1e-08 34.5 0.9 8.7e-08 31.5 0.9 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EJP65107.1 - 1.2e-05 24.5 1.4 2.4e-05 23.6 1.4 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase HD PF01966.22 EJP65108.1 - 5.3e-06 26.7 0.0 7.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 HD domain Pro-kuma_activ PF09286.11 EJP65109.1 - 1.1e-41 142.4 0.1 1.5e-40 138.7 0.0 2.4 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP65109.1 - 0.00085 18.7 1.3 0.0015 17.9 1.3 1.3 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_75 PF07335.11 EJP65110.1 - 1.9e-63 213.6 0.9 2.3e-63 213.4 0.9 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF3012 PF11216.8 EJP65110.1 - 0.067 13.2 1.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) MFS_1 PF07690.16 EJP65111.1 - 3e-28 98.8 23.8 3e-28 98.8 23.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP65111.1 - 6.1e-06 25.4 12.4 9e-06 24.8 12.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1600 PF07667.11 EJP65111.1 - 0.067 13.4 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) Neprosin PF03080.15 EJP65112.1 - 2.9e-48 164.1 5.4 3.9e-48 163.7 5.4 1.2 1 0 0 1 1 1 1 Neprosin Beta_elim_lyase PF01212.21 EJP65113.1 - 6.8e-39 133.9 0.0 8.9e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EJP65113.1 - 3.1e-06 26.6 0.0 4.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EJP65113.1 - 5.3e-05 22.3 0.1 6.6e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V E1-E2_ATPase PF00122.20 EJP65114.1 - 3.2e-36 124.6 0.6 9.6e-36 123.0 0.6 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EJP65114.1 - 1.6e-19 71.1 4.2 9e-19 68.6 4.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EJP65114.1 - 1.5e-15 57.4 9.8 1.7e-14 53.9 6.3 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EJP65114.1 - 5.1e-15 54.9 0.0 1.6e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EJP65114.1 - 1.6e-07 31.3 0.0 4.1e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EJP65114.1 - 0.002 17.9 0.0 0.073 12.8 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase COX7C PF02935.16 EJP65114.1 - 0.011 16.0 0.2 0.011 16.0 0.2 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc FAD_binding_3 PF01494.19 EJP65115.1 - 9.5e-19 67.8 1.0 6.7e-18 65.1 1.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EJP65115.1 - 2.6e-06 27.6 0.3 1.1e-05 25.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP65115.1 - 3.3e-05 23.6 2.0 0.0026 17.4 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EJP65115.1 - 4.1e-05 22.6 0.4 0.1 11.5 0.1 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EJP65115.1 - 5.7e-05 22.5 0.2 0.00044 19.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP65115.1 - 0.00015 20.9 0.8 0.00031 20.0 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EJP65115.1 - 0.0017 17.5 0.5 0.003 16.7 0.5 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EJP65115.1 - 0.0025 17.2 0.4 0.0054 16.1 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP65115.1 - 0.0055 15.5 0.4 0.01 14.6 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 EJP65115.1 - 0.031 13.9 0.5 0.071 12.8 0.2 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EJP65115.1 - 0.042 13.1 0.8 0.094 12.0 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 EJP65115.1 - 0.063 12.5 0.3 0.17 11.2 0.3 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EJP65115.1 - 0.074 13.6 0.3 0.22 12.1 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2306 PF10067.9 EJP65116.1 - 3.6e-15 56.5 6.1 3.6e-15 56.5 6.1 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) G_glu_transpept PF01019.21 EJP65117.1 - 1.2e-139 466.4 0.0 1.3e-139 466.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glutaredoxin PF00462.24 EJP65118.1 - 1.4e-16 60.4 0.0 2.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin PknH_C PF14032.6 EJP65119.1 - 0.032 14.1 0.1 0.056 13.3 0.1 1.3 1 0 0 1 1 1 0 PknH-like extracellular domain MIF4G PF02854.19 EJP65119.1 - 0.077 12.6 1.0 0.22 11.2 1.0 1.8 1 1 0 1 1 1 0 MIF4G domain Mobilization_B PF17511.2 EJP65119.1 - 3.2 8.1 5.9 0.62 10.4 1.3 1.9 1 1 0 2 2 2 0 Mobilization protein B Aminotran_4 PF01063.19 EJP65120.1 - 3e-26 92.7 0.0 3.9e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV CBM9_2 PF16011.5 EJP65121.1 - 1.7e-05 24.7 0.3 3e-05 23.8 0.3 1.3 1 1 0 1 1 1 1 Carbohydrate-binding family 9 Ras PF00071.22 EJP65122.1 - 2.5e-56 189.7 0.0 3.2e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP65122.1 - 6.9e-22 77.9 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP65122.1 - 6.9e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EJP65122.1 - 0.0028 17.1 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EJP65122.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Aa_trans PF01490.18 EJP65123.1 - 1e-69 235.3 25.3 1.2e-69 235.1 25.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Claudin_2 PF13903.6 EJP65123.1 - 0.34 10.6 11.1 1.4 8.7 3.6 2.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Asp PF00026.23 EJP65124.1 - 9.6e-65 219.1 10.8 1.3e-64 218.6 10.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP65124.1 - 1.1e-08 35.5 14.9 2.2e-08 34.6 7.4 3.4 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EJP65124.1 - 0.00081 19.2 0.0 0.0042 16.9 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EJP65124.1 - 0.19 12.4 3.1 2 9.1 0.1 3.4 3 2 1 4 4 4 0 Aspartyl protease PPTA PF01239.22 EJP65125.1 - 7.1e-07 28.8 8.3 0.0074 16.0 0.3 4.6 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.14 EJP65126.1 - 2.2e-61 206.4 0.4 3.2e-61 205.8 0.4 1.2 1 0 0 1 1 1 1 CHD5-like protein AAA_33 PF13671.6 EJP65127.1 - 4.3e-05 23.7 0.1 0.16 12.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EJP65127.1 - 0.00028 20.2 0.1 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EJP65127.1 - 0.00075 20.1 0.0 0.014 15.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EJP65127.1 - 0.00096 19.2 0.0 0.0011 19.1 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EJP65127.1 - 0.0013 19.2 0.1 0.0019 18.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP65127.1 - 0.0041 17.4 0.0 0.015 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EJP65127.1 - 0.0041 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ParA PF10609.9 EJP65127.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF2075 PF09848.9 EJP65127.1 - 0.035 13.3 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EJP65127.1 - 0.049 13.4 0.2 0.35 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain SelK_SelG PF10961.8 EJP65127.1 - 0.053 14.1 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG T2SSE PF00437.20 EJP65127.1 - 0.062 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PRK PF00485.18 EJP65127.1 - 0.067 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AIG1 PF04548.16 EJP65127.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family NACHT PF05729.12 EJP65127.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Ploopntkinase3 PF18751.1 EJP65127.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 EJP65127.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 EJP65127.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EJP65127.1 - 0.2 12.1 0.0 0.32 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Fungal_trans PF04082.18 EJP65128.1 - 5.5e-13 48.6 0.0 6.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_3 PF07969.11 EJP65129.1 - 1.7e-07 31.1 0.0 3.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EJP65129.1 - 1.7e-07 30.9 0.1 8e-07 28.7 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family ECH_1 PF00378.20 EJP65130.1 - 2.2e-39 135.3 0.1 6.8e-39 133.7 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP65130.1 - 2.1e-18 66.9 0.1 4.5e-18 65.8 0.1 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EJP65130.1 - 0.19 11.7 0.1 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 FAD_binding_3 PF01494.19 EJP65131.1 - 0.0001 21.7 2.0 0.0012 18.2 2.0 2.4 1 1 0 1 1 1 1 FAD binding domain GRAB PF10375.9 EJP65133.1 - 3e-09 36.4 0.1 6.2e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Spc7 PF08317.11 EJP65133.1 - 0.00038 19.4 33.2 0.00038 19.4 33.2 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein Atg14 PF10186.9 EJP65133.1 - 0.002 17.3 27.0 0.002 17.3 27.0 2.9 1 1 2 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EJP65133.1 - 0.0056 16.8 17.2 0.0056 16.8 17.2 4.7 2 1 3 5 5 5 1 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 EJP65133.1 - 0.012 15.8 11.5 0.012 15.8 11.5 5.6 2 1 2 5 5 4 0 ABC transporter C-terminal domain Filament PF00038.21 EJP65133.1 - 0.031 13.9 60.0 0.15 11.6 14.4 2.3 1 1 1 2 2 2 0 Intermediate filament protein AIP3 PF03915.13 EJP65133.1 - 0.044 12.9 40.0 0.086 11.9 14.6 3.3 1 1 2 3 3 3 0 Actin interacting protein 3 Baculo_PEP_C PF04513.12 EJP65133.1 - 0.049 13.7 21.0 1.5 8.8 4.3 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 EJP65133.1 - 0.16 11.3 59.4 0.037 13.4 17.2 3.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EJP65133.1 - 0.24 11.2 57.4 0.1 12.4 20.9 3.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH NPV_P10 PF05531.12 EJP65133.1 - 0.89 10.1 23.1 0.52 10.8 0.3 4.0 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 EJP65133.1 - 1.5 6.2 59.5 1.9 5.9 58.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 EJP65133.1 - 1.9 8.9 30.1 1.1 9.7 2.8 6.2 2 1 2 5 5 5 0 Flagella accessory protein C (FlaC) AP_endonuc_2 PF01261.24 EJP65133.1 - 3.5 7.0 9.7 4.2 6.8 0.3 2.6 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel TPR_MLP1_2 PF07926.12 EJP65133.1 - 4.7 7.3 71.0 0.056 13.5 10.3 4.9 3 1 3 6 6 5 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 EJP65133.1 - 5.4 6.4 59.6 5.7 6.3 26.5 3.3 1 1 3 4 4 4 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 EJP65133.1 - 8.6 6.5 36.4 8.4 6.6 3.7 3.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.22 EJP65134.1 - 3.3e-16 58.9 0.0 7.4e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EJP65134.1 - 0.0099 15.9 0.1 0.027 14.5 0.1 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EJP65134.1 - 0.035 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN PF06003.12 EJP65135.1 - 1.5e-05 24.4 5.8 0.0065 15.8 0.1 2.3 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) Cu_bind_like PF02298.17 EJP65136.1 - 0.0037 17.2 0.0 0.013 15.5 0.0 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain 4F5 PF04419.14 EJP65137.1 - 3e-08 34.4 15.7 3e-08 34.4 15.7 2.2 2 0 0 2 2 2 1 4F5 protein family DFRP_C PF16543.5 EJP65137.1 - 1 9.9 7.4 1.4 9.5 7.4 1.3 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 CFIA_Pcf11 PF11526.8 EJP65139.1 - 0.00015 22.1 4.4 0.00075 19.9 2.7 2.2 1 1 1 2 2 2 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.19 EJP65139.1 - 0.02 14.8 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 VHS domain Zn-C2H2_12 PF18112.1 EJP65139.1 - 0.056 13.9 0.7 3.2 8.3 0.2 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 EJP65139.1 - 0.073 14.0 1.4 17 6.6 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP65139.1 - 0.13 12.8 1.1 7.4 7.2 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_UBZ PF18439.1 EJP65139.1 - 2.4 7.8 8.7 1.1 8.9 2.6 2.9 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 EJP65139.1 - 9.6 6.2 6.0 35 4.4 2.9 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 ICMT PF04140.14 EJP65140.1 - 3.4e-10 40.2 1.6 7.9e-09 35.8 0.1 2.9 2 2 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EJP65140.1 - 5.4e-05 23.5 0.6 5.4e-05 23.5 0.6 3.0 4 0 0 4 4 4 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EJP65140.1 - 0.0066 15.2 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MgsA_C PF12002.8 EJP65141.1 - 1.5e-59 200.7 0.1 3.2e-59 199.6 0.1 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EJP65141.1 - 7.6e-22 77.4 0.1 2.1e-21 76.0 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EJP65141.1 - 9.7e-14 51.9 0.0 2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EJP65141.1 - 1.3e-08 34.7 0.0 3.3e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EJP65141.1 - 2.9e-06 27.1 0.0 5.8e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EJP65141.1 - 4.4e-06 27.2 2.0 0.0038 17.6 0.0 3.1 1 1 2 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EJP65141.1 - 3.6e-05 23.8 0.1 0.00025 21.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EJP65141.1 - 0.0001 21.8 0.2 0.087 12.2 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EJP65141.1 - 0.0004 20.7 0.2 0.0016 18.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EJP65141.1 - 0.0012 18.1 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EJP65141.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EJP65141.1 - 0.0076 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 EJP65141.1 - 0.0082 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EJP65141.1 - 0.011 15.5 0.0 0.45 10.3 0.0 2.2 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 EJP65141.1 - 0.012 16.0 0.4 0.053 13.9 0.3 1.9 1 1 1 2 2 2 0 AAA domain ResIII PF04851.15 EJP65141.1 - 0.016 15.2 0.3 0.87 9.6 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.22 EJP65141.1 - 0.022 14.9 0.1 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate kinase AAA_30 PF13604.6 EJP65141.1 - 0.024 14.3 0.3 0.024 14.3 0.3 2.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EJP65141.1 - 0.032 14.7 0.0 0.048 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EJP65141.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EJP65141.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 EJP65141.1 - 0.085 13.1 1.2 0.31 11.3 1.2 1.9 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EJP65141.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EJP65141.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EJP65141.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain XPG_I PF00867.18 EJP65142.1 - 2.1e-25 88.9 0.0 4.3e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 EJP65142.1 - 1.5e-22 80.5 0.1 1.5e-22 80.5 0.1 2.5 3 0 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 EJP65142.1 - 3.1e-06 27.6 0.0 7.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.19 EJP65143.1 - 6.7e-21 74.4 0.0 1.1e-19 70.4 0.0 2.6 2 1 0 2 2 2 1 Actin tRNA-synt_2b PF00587.25 EJP65144.1 - 5.7e-15 55.7 0.0 2.6e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EJP65144.1 - 1.1e-07 32.1 1.4 3.7e-07 30.3 1.4 1.8 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain eIF-4B PF06273.11 EJP65144.1 - 0.094 11.8 0.3 0.17 10.9 0.3 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B CorA PF01544.18 EJP65145.1 - 3.6e-07 29.8 0.0 8.4e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3402 PF11882.8 EJP65145.1 - 0.036 13.2 1.4 0.06 12.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Nbs1_C PF08599.10 EJP65145.1 - 0.27 11.4 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 PPR PF01535.20 EJP65145.1 - 0.67 10.3 2.5 1.3 9.5 0.8 2.4 2 0 0 2 2 2 0 PPR repeat DUF2868 PF11067.8 EJP65145.1 - 2 7.8 7.2 1.5 8.2 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2868) Pkinase PF00069.25 EJP65146.1 - 1.1e-71 241.3 0.0 2e-71 240.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP65146.1 - 5e-37 127.6 0.0 8.7e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP65146.1 - 2.7e-08 33.5 0.3 6.5e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EJP65146.1 - 0.23 10.5 0.0 0.57 9.2 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 TFIIA PF03153.13 EJP65146.1 - 0.7 9.8 42.7 1.3 8.9 42.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lectin_leg-like PF03388.13 EJP65147.1 - 1.1e-65 221.2 0.0 1.4e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EJP65147.1 - 1.6e-07 31.5 0.0 2.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EJP65147.1 - 0.0011 18.6 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.10 EJP65147.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 zf-Tim10_DDP PF02953.15 EJP65148.1 - 2.8e-19 68.5 2.7 3.3e-19 68.3 2.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RNF111_N PF15303.6 EJP65148.1 - 0.017 14.9 0.0 0.017 14.9 0.0 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus BAR_2 PF10455.9 EJP65148.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3398 PF11878.8 EJP65148.1 - 0.12 12.8 0.1 0.2 12.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) DUF2040 PF09745.9 EJP65149.1 - 3.1e-37 127.3 24.0 3.1e-37 127.3 24.0 4.3 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF2315 PF10231.9 EJP65149.1 - 0.018 15.1 3.3 0.018 15.1 3.3 2.4 2 1 0 2 2 2 0 Apoptogenic protein 1 UBA_4 PF14555.6 EJP65150.1 - 3.4e-06 26.8 0.1 5.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.20 EJP65150.1 - 0.0019 18.2 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 LysM domain CAP_N PF01213.19 EJP65150.1 - 0.06 12.8 4.8 0.093 12.2 4.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MMS1_N PF10433.9 EJP65151.1 - 1.7e-154 515.1 0.0 2.4e-154 514.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EJP65151.1 - 1e-101 340.5 0.0 6.6e-101 337.8 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region zf-Mss51 PF13824.6 EJP65152.1 - 1e-28 99.1 7.0 2e-28 98.3 7.0 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EJP65152.1 - 0.0022 18.0 0.5 0.0022 18.0 0.5 2.2 2 0 0 2 2 2 1 MYND finger DUF3306 PF11748.8 EJP65152.1 - 0.18 12.7 1.1 0.34 11.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) zf-C2H2 PF00096.26 EJP65152.1 - 2.6 8.7 5.5 0.33 11.5 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type PXA PF02194.15 EJP65153.1 - 3.2e-45 154.3 0.4 5.4e-45 153.6 0.4 1.4 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EJP65153.1 - 0.12 13.0 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 0 Sorting nexin C terminal HTH_Tnp_Tc5 PF03221.16 EJP65154.1 - 3.6e-10 39.7 0.0 7.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MMR_HSR1_Xtn PF16897.5 EJP65155.1 - 1.3e-41 140.9 1.3 3.4e-40 136.3 0.3 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EJP65155.1 - 4.5e-22 77.8 0.2 8.2e-22 77.0 0.2 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EJP65155.1 - 9.5e-21 74.0 0.0 2.7e-20 72.6 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJP65155.1 - 1.6e-09 37.4 0.0 7.1e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EJP65155.1 - 0.0002 21.4 0.0 0.044 13.8 0.0 2.3 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 EJP65155.1 - 0.00092 18.8 0.1 6.4 6.3 0.0 3.8 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EJP65155.1 - 0.027 13.5 0.1 0.064 12.2 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 EJP65155.1 - 0.039 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Arf PF00025.21 EJP65155.1 - 0.045 13.2 0.1 9.3 5.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EJP65155.1 - 0.047 13.6 0.2 5.8 6.8 0.1 2.7 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EJP65155.1 - 0.09 13.0 0.1 0.65 10.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain CBS PF00571.28 EJP65155.1 - 0.13 12.7 0.1 0.38 11.2 0.1 1.8 1 0 0 1 1 1 0 CBS domain Roc PF08477.13 EJP65155.1 - 0.14 12.3 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 EJP65156.1 - 1.5e-21 76.8 0.0 4.6e-15 56.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP65156.1 - 9.4e-14 51.6 0.1 2.4e-08 34.3 0.0 4.7 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EJP65156.1 - 3.8e-13 49.2 0.9 0.00061 20.1 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EJP65156.1 - 1e-12 47.0 0.1 0.0022 18.3 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EJP65156.1 - 2.6e-11 43.5 0.4 9.4e-05 22.6 0.2 3.7 2 1 0 3 3 3 2 Ankyrin repeats (many copies) 2OG-FeII_Oxy_2 PF13532.6 EJP65157.1 - 3e-13 50.4 0.0 1.1e-12 48.5 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.16 EJP65158.1 - 2.3e-13 50.4 2.2 4.4e-13 49.5 2.2 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PRIMA1 PF16101.5 EJP65158.1 - 1.5e-05 25.0 5.3 3.8e-05 23.7 5.3 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CAP_N PF01213.19 EJP65158.1 - 0.093 12.2 6.7 0.14 11.6 6.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EJP65158.1 - 0.12 12.4 1.6 0.18 11.9 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator WSC PF01822.19 EJP65159.1 - 7.7e-34 115.7 25.1 1.1e-19 70.4 5.0 5.7 6 0 0 6 6 6 2 WSC domain PCI PF01399.27 EJP65160.1 - 4.7e-09 36.7 0.6 7.9e-08 32.8 0.1 2.8 2 0 0 2 2 2 1 PCI domain ubiquitin PF00240.23 EJP65161.1 - 0.00031 20.4 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 EJP65161.1 - 0.03 15.0 0.0 0.048 14.3 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD G-gamma PF00631.22 EJP65162.1 - 7.5e-24 83.5 0.0 9.1e-24 83.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.9 EJP65163.1 - 2.7e-23 81.9 1.0 3.6e-22 78.3 1.0 2.1 1 1 0 1 1 1 1 Rdx family Metallophos PF00149.28 EJP65164.1 - 4.7e-40 138.3 0.1 6.1e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EJP65164.1 - 3.1e-23 81.9 2.0 4.4e-23 81.5 1.3 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain zf-HC5HC2H_2 PF13832.6 EJP65165.1 - 3e-33 114.3 8.8 3e-33 114.3 8.8 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 EJP65165.1 - 1.8e-28 99.9 0.1 1.8e-28 99.9 0.1 3.8 4 0 0 4 4 4 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 EJP65165.1 - 1.1e-25 89.6 8.9 1.1e-25 89.6 8.9 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EJP65165.1 - 1.2e-14 53.5 2.2 1.2e-14 53.5 2.2 2.5 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 EJP65165.1 - 1.1e-08 34.8 26.3 1e-07 31.7 12.6 2.7 2 0 0 2 2 2 2 PHD-finger Spt20 PF12090.8 EJP65165.1 - 0.0032 17.1 1.8 0.0066 16.1 1.8 1.5 1 0 0 1 1 1 1 Spt20 family CDC45 PF02724.14 EJP65165.1 - 4 5.6 12.0 6.7 4.9 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3801 PF12687.7 EJP65165.1 - 4.9 7.2 10.6 22 5.0 4.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) zf-PHD-like PF15446.6 EJP65165.1 - 6.7 6.3 15.8 0.03 13.9 1.9 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF913 PF06025.12 EJP65165.1 - 7.7 5.4 7.2 0.34 9.8 1.2 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) LRR_4 PF12799.7 EJP65166.1 - 1.1e-13 51.1 2.9 0.0014 19.0 1.2 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EJP65166.1 - 2.7e-11 43.0 8.6 3.5e-08 33.1 2.1 3.5 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 EJP65166.1 - 0.00073 19.7 4.4 42 5.2 0.5 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EJP65166.1 - 0.0069 16.4 8.5 4.7 7.5 0.0 5.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 EJP65166.1 - 0.026 14.0 0.1 0.06 12.8 0.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeat Biotin_lipoyl PF00364.22 EJP65168.1 - 5e-19 67.9 0.2 1.1e-18 66.9 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EJP65168.1 - 2.4e-09 37.4 0.0 7.1e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EJP65168.1 - 0.0004 20.1 0.0 0.0038 17.0 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 EJP65168.1 - 0.071 13.8 0.0 0.29 11.9 0.0 2.1 2 0 0 2 2 2 0 HlyD family secretion protein Fungal_trans PF04082.18 EJP65169.1 - 1.7e-09 37.1 0.2 7.8e-09 35.0 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain DUF1908 PF08926.11 EJP65169.1 - 0.071 12.2 1.5 0.1 11.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) OPT PF03169.15 EJP65170.1 - 1.1e-173 579.2 48.2 1.3e-173 579.0 48.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.14 EJP65170.1 - 0.12 12.5 0.3 0.12 12.5 0.3 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) ketoacyl-synt PF00109.26 EJP65171.1 - 4.4e-61 206.6 1.6 4.4e-61 206.6 1.6 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EJP65171.1 - 7.1e-36 122.8 2.0 1.5e-35 121.8 2.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EJP65171.1 - 9.8e-05 21.8 0.7 0.0007 19.0 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubiq_cyt_C_chap PF03981.12 EJP65172.1 - 3.5e-31 108.2 0.8 9.7e-31 106.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone DHFR_1 PF00186.19 EJP65173.1 - 1.5e-30 106.0 0.0 2.5e-29 102.0 0.0 2.3 1 1 0 1 1 1 1 Dihydrofolate reductase Sporozoite_P67 PF05642.11 EJP65174.1 - 0.11 10.6 2.3 0.11 10.6 2.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Fungal_trans_2 PF11951.8 EJP65175.1 - 1.8e-06 27.0 0.2 3.2e-06 26.2 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain DSBA PF01323.20 EJP65176.1 - 9.2e-20 71.2 0.0 1.7e-19 70.4 0.0 1.4 1 1 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.25 EJP65177.1 - 1.9e-25 89.5 0.0 1.1e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EJP65177.1 - 9.2e-21 74.5 0.3 2.2e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP65177.1 - 0.18 11.7 0.3 0.58 10.0 0.3 1.7 1 1 0 1 1 1 0 KR domain AAA PF00004.29 EJP65178.1 - 2.3e-49 167.2 0.0 1.5e-42 145.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP65178.1 - 2.9e-11 43.0 0.6 4.4e-10 39.2 0.1 2.7 3 0 0 3 3 2 1 AAA+ lid domain IstB_IS21 PF01695.17 EJP65178.1 - 1.2e-06 28.4 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EJP65178.1 - 2.9e-05 24.3 0.0 6.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EJP65178.1 - 9.8e-05 22.8 3.1 0.00044 20.7 0.2 3.3 3 1 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 EJP65178.1 - 0.0011 19.2 0.3 0.017 15.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EJP65178.1 - 0.0027 18.0 1.7 0.022 15.0 0.1 2.9 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 EJP65178.1 - 0.007 16.4 0.0 0.033 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EJP65178.1 - 0.013 16.0 0.9 0.057 14.0 0.0 2.7 3 0 0 3 3 1 0 AAA domain RuvB_N PF05496.12 EJP65178.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EJP65178.1 - 0.037 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 EJP65178.1 - 0.041 13.1 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EJP65178.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJP65178.1 - 0.056 14.0 1.3 1.7 9.2 0.0 3.6 4 0 0 4 4 4 0 ABC transporter Mg_chelatase PF01078.21 EJP65178.1 - 0.066 12.6 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ribosomal_L6e_N PF03868.15 EJP65178.1 - 0.07 13.4 0.4 0.17 12.1 0.4 1.6 1 0 0 1 1 1 0 Ribosomal protein L6, N-terminal domain AAA_28 PF13521.6 EJP65178.1 - 0.09 13.0 1.3 0.16 12.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain Torsin PF06309.11 EJP65178.1 - 0.1 12.7 0.1 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Torsin NACHT PF05729.12 EJP65178.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 EJP65178.1 - 0.12 12.5 0.0 0.96 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Bromodomain PF00439.25 EJP65178.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Bromodomain AAA_7 PF12775.7 EJP65178.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Dus PF01207.17 EJP65179.1 - 3.9e-55 187.1 0.0 6.9e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EJP65179.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Mannosidase_ig PF17786.1 EJP65182.1 - 1.2e-13 51.5 0.1 5.8e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EJP65182.1 - 1.5e-06 28.8 0.0 5.4e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EJP65182.1 - 1.5e-05 25.0 0.0 4.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 EJP65182.1 - 7e-05 22.5 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 EJP65182.1 - 0.0077 15.4 0.1 0.015 14.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Nbl1_Borealin_N PF10444.9 EJP65182.1 - 0.12 12.1 0.2 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Fungal_trans PF04082.18 EJP65183.1 - 1.7e-22 79.7 0.0 2.7e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65183.1 - 5.5e-09 36.0 11.5 1.5e-08 34.6 11.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MA3 PF02847.17 EJP65184.1 - 1.9e-23 82.6 0.2 6.4e-23 80.9 0.0 2.1 3 0 0 3 3 3 1 MA3 domain DPM2 PF07297.12 EJP65185.1 - 2.4e-30 104.7 2.4 2.7e-30 104.5 2.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EJP65185.1 - 0.001 19.0 0.9 0.0011 18.9 0.9 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 EJP65185.1 - 0.0026 17.8 7.9 0.014 15.5 7.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4229) LapA_dom PF06305.11 EJP65185.1 - 0.0036 17.1 0.7 0.0036 17.1 0.7 1.7 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 EJP65185.1 - 0.049 13.7 2.1 0.052 13.6 2.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III COX14 PF14880.6 EJP65185.1 - 0.076 12.9 3.8 0.96 9.3 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Pro-kuma_activ PF09286.11 EJP65187.1 - 2.4e-22 79.8 0.0 6.4e-22 78.4 0.0 1.8 1 1 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP65187.1 - 1.5e-08 34.3 0.1 2e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Subtilase family SnoaL_2 PF12680.7 EJP65188.1 - 0.00047 20.8 0.2 0.00069 20.2 0.2 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EJP65188.1 - 0.00071 19.7 0.3 0.0011 19.1 0.3 1.5 1 1 0 1 1 1 1 SnoaL-like domain PHD PF00628.29 EJP65189.1 - 3.1e-05 23.8 6.0 5.7e-05 22.9 6.0 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 EJP65189.1 - 0.0019 18.8 0.7 0.009 16.6 0.0 2.2 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF3807 PF12720.7 EJP65189.1 - 2.1 8.6 10.4 9 6.5 10.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PHD_2 PF13831.6 EJP65189.1 - 2.1 8.0 4.9 1.7 8.2 2.5 2.0 2 0 0 2 2 2 0 PHD-finger SBD_N PF07005.11 EJP65191.1 - 6.5e-58 196.1 0.0 1.4e-57 195.1 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 EJP65191.1 - 3.7e-42 144.7 3.1 8.3e-42 143.6 3.1 1.6 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain NAD_binding_2 PF03446.15 EJP65191.1 - 2.1e-13 50.8 1.0 8.9e-13 48.7 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glu_syn_central PF04898.14 EJP65191.1 - 0.053 13.0 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Glutamate synthase central domain F420_oxidored PF03807.17 EJP65191.1 - 0.21 12.2 2.8 1.2 9.7 0.4 3.0 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Zn_clus PF00172.18 EJP65192.1 - 4.4e-07 29.9 8.6 8e-07 29.1 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP65192.1 - 2.2e-05 23.6 0.1 4.4e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EJP65193.1 - 9.4e-39 133.3 30.4 9.4e-39 133.3 30.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Bactofilin PF04519.13 EJP65194.1 - 7.6e-08 32.5 2.9 0.00061 20.0 0.1 2.2 1 1 1 2 2 2 2 Polymer-forming cytoskeletal FapA PF03961.13 EJP65194.1 - 0.0014 17.3 0.4 0.0019 16.9 0.4 1.3 1 0 0 1 1 1 1 Flagellar Assembly Protein A CEND1 PF15677.5 EJP65195.1 - 1.7 9.2 16.1 3.1 8.3 16.1 1.4 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Pol_alpha_B_N PF08418.10 EJP65195.1 - 4.1 7.3 8.4 5.6 6.9 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-C2H2 PF00096.26 EJP65196.1 - 0.013 15.9 2.7 0.036 14.5 2.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3602 PF12223.8 EJP65198.1 - 1.2e-14 54.7 15.4 5.8e-06 26.8 4.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Pam16 PF03656.13 EJP65199.1 - 5.9e-07 29.5 0.0 6.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EJP65199.1 - 7.4e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 EJP65199.1 - 0.0099 15.5 1.1 0.028 14.0 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3918) DUF397 PF04149.12 EJP65200.1 - 0.073 13.1 0.2 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF397) Nuc_deoxyrib_tr PF05014.15 EJP65200.1 - 0.18 11.8 1.7 4 7.5 0.1 2.3 1 1 1 2 2 2 0 Nucleoside 2-deoxyribosyltransferase Ku_PK_bind PF08785.11 EJP65201.1 - 3e-38 130.6 0.1 9.3e-38 129.1 0.0 1.9 2 0 0 2 2 2 1 Ku C terminal domain like Ku PF02735.16 EJP65201.1 - 2.9e-24 85.9 0.0 7.7e-24 84.5 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EJP65201.1 - 1.9e-12 47.4 0.0 3.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EJP65201.1 - 0.0045 17.7 0.4 0.014 16.1 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 EJP65201.1 - 0.029 14.6 0.1 0.061 13.6 0.1 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4149 PF13664.6 EJP65202.1 - 2.5e-24 85.6 1.6 2.5e-24 85.6 1.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) FA_hydroxylase PF04116.13 EJP65205.1 - 3.4e-26 92.1 22.3 1.1e-25 90.5 20.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_4 PF08386.10 EJP65206.1 - 6.3e-20 71.2 0.0 1.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EJP65206.1 - 2.1e-17 63.6 0.0 2.7e-13 50.1 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_6 PF13344.6 EJP65207.1 - 1.3e-29 102.2 0.0 2e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP65207.1 - 1.2e-14 55.1 0.0 4e-06 27.3 0.0 3.0 1 1 2 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP65207.1 - 2e-14 53.4 0.1 6.6e-14 51.7 0.1 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 EJP65207.1 - 0.00019 21.6 0.1 0.16 12.0 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF1295 PF06966.12 EJP65208.1 - 3.4e-33 115.1 11.7 4.4e-33 114.8 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EJP65208.1 - 0.0078 16.6 1.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 EJP65209.1 - 2.4e-103 346.3 0.0 7.1e-99 331.6 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 EJP65209.1 - 4e-19 68.8 0.0 8.2e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Stb3 PF10330.9 EJP65211.1 - 8.4e-38 128.3 0.0 1.3e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Glyco_transf_25 PF01755.17 EJP65212.1 - 2.3e-09 37.4 0.0 7.9e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Mito_fiss_reg PF05308.11 EJP65212.1 - 6.1 6.9 5.3 9.8 6.2 5.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-C2H2 PF00096.26 EJP65214.1 - 1.7e-05 25.0 3.7 1.7e-05 25.0 3.7 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP65214.1 - 4.3e-05 24.0 2.5 4.3e-05 24.0 2.5 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EJP65214.1 - 6.8e-05 23.1 4.2 6.8e-05 23.1 4.2 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EJP65214.1 - 0.00065 19.9 1.1 0.00065 19.9 1.1 1.9 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EJP65214.1 - 0.014 15.4 2.3 0.03 14.3 2.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EJP65214.1 - 0.02 15.2 4.5 0.057 13.7 4.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon ARS2 PF04959.13 EJP65214.1 - 0.048 14.0 7.0 0.035 14.5 2.8 2.6 3 0 0 3 3 3 0 Arsenite-resistance protein 2 zf-met PF12874.7 EJP65214.1 - 0.058 13.8 0.8 0.14 12.6 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 EJP65214.1 - 0.26 11.2 1.8 0.57 10.2 1.8 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-TRAF PF02176.18 EJP65214.1 - 1.1 10.0 7.3 0.14 12.8 3.1 1.7 2 0 0 2 2 1 0 TRAF-type zinc finger zf-C2H2_2 PF12756.7 EJP65214.1 - 1.7 9.0 4.7 1.8 8.9 3.0 2.0 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 EJP65214.1 - 2.6 8.7 7.4 7.5 7.3 0.4 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2HE PF16278.5 EJP65214.1 - 6.7 7.2 6.6 7.4 7.1 5.0 2.0 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Fungal_trans PF04082.18 EJP65215.1 - 3.3e-08 32.9 0.3 6.4e-08 31.9 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65215.1 - 9.9e-08 32.0 11.2 9.9e-08 32.0 11.2 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4803 PF16061.5 EJP65215.1 - 0.027 13.9 1.2 0.043 13.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) CD34_antigen PF06365.12 EJP65217.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Herpes_LMP1 PF05297.11 EJP65217.1 - 0.06 12.5 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PUF PF00806.19 EJP65218.1 - 2.3e-61 200.2 8.9 1.4e-08 34.0 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EJP65218.1 - 0.012 16.0 4.9 5.5 7.3 0.1 4.0 1 1 2 3 3 3 0 CPL (NUC119) domain Methyltransf_8 PF05148.15 EJP65218.1 - 0.077 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF1640 PF07798.11 EJP65219.1 - 1.9e-47 161.6 6.3 1.9e-47 161.6 6.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) OATP PF03137.20 EJP65219.1 - 0.0088 14.4 0.0 0.0088 14.4 0.0 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF4834 PF16118.5 EJP65219.1 - 0.01 16.8 3.0 0.01 16.8 3.0 4.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 EJP65219.1 - 0.098 11.0 1.2 0.17 10.3 1.2 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1664 PF07889.12 EJP65219.1 - 0.11 12.6 2.5 0.28 11.2 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EJP65219.1 - 0.22 9.4 2.9 0.31 8.9 2.9 1.1 1 0 0 1 1 1 0 Prominin Herpes_glycop PF01528.16 EJP65219.1 - 0.31 9.8 2.7 0.55 9.0 2.7 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Nnf1 PF03980.14 EJP65220.1 - 9.9e-33 112.8 6.1 9.9e-33 112.8 6.1 2.2 2 0 0 2 2 2 1 Nnf1 RuvB_N PF05496.12 EJP65220.1 - 0.097 12.4 0.1 0.54 10.0 0.1 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF948 PF06103.11 EJP65220.1 - 0.32 11.3 2.4 0.83 10.0 0.3 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PH_9 PF15410.6 EJP65221.1 - 7e-05 23.2 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EJP65221.1 - 0.0035 17.8 0.1 0.011 16.2 0.1 1.9 1 1 0 1 1 1 1 PH domain NTF2 PF02136.20 EJP65222.1 - 1.2e-26 93.7 0.2 2e-26 92.9 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EJP65222.1 - 0.00013 21.7 0.1 0.00025 20.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M20 PF01546.28 EJP65223.1 - 4.2e-20 72.3 0.3 7.6e-20 71.5 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJP65223.1 - 1.8e-13 50.4 0.1 4.3e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Pectate_lyase_3 PF12708.7 EJP65224.1 - 1.3e-16 61.1 6.6 3.1e-14 53.3 2.5 2.4 2 1 0 2 2 2 2 Pectate lyase superfamily protein RL10P_insert PF17777.1 EJP65225.1 - 2.8e-19 68.9 0.0 4.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EJP65225.1 - 7.9e-19 67.7 0.0 1.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.8 EJP65226.1 - 3.8e-24 85.1 5.4 8e-24 84.1 5.4 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EJP65226.1 - 1.4e-15 56.8 0.1 5e-15 55.1 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP65226.1 - 5.5e-05 23.2 0.0 8.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Keratin_2_head PF16208.5 EJP65226.1 - 5 7.2 24.2 11 6.1 24.2 1.5 1 0 0 1 1 1 0 Keratin type II head L51_S25_CI-B8 PF05047.16 EJP65227.1 - 2.1e-14 53.2 0.0 4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GHL10 PF02638.15 EJP65227.1 - 0.15 11.1 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 TIM PF00121.18 EJP65228.1 - 3.9e-86 288.4 0.4 4.5e-86 288.2 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase zf-C2H2 PF00096.26 EJP65229.1 - 1 10.0 4.5 0.81 10.3 0.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_clus PF00172.18 EJP65231.1 - 0.0003 20.8 12.9 0.00055 20.0 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2207 PF09972.9 EJP65232.1 - 0.062 12.1 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LptF_LptG PF03739.14 EJP65232.1 - 0.093 11.6 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Feld-I_B PF09252.10 EJP65232.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Allergen Fel d I-B chain DUF543 PF04418.12 EJP65233.1 - 1.6e-29 101.7 0.0 2e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ABC_cobalt PF09819.9 EJP65233.1 - 0.063 13.4 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component Urb2 PF10441.9 EJP65234.1 - 1.8e-62 210.9 2.7 6.9e-62 209.0 0.2 2.6 2 0 0 2 2 2 1 Urb2/Npa2 family adh_short PF00106.25 EJP65235.1 - 5.6e-30 104.3 0.0 7.4e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP65235.1 - 2.6e-23 82.8 0.2 3.7e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP65235.1 - 7.8e-11 42.2 0.3 2.5e-10 40.6 0.3 1.7 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EJP65235.1 - 0.0035 17.9 0.0 0.13 12.8 0.1 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 EJP65235.1 - 0.0092 15.9 0.7 0.084 12.8 0.7 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 EJP65235.1 - 0.022 14.5 0.1 0.058 13.1 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 EJP65235.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 EJP65235.1 - 0.15 11.9 0.4 0.31 10.8 0.4 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NRDE-2 PF08424.10 EJP65236.1 - 4.8e-98 328.2 3.0 6.7e-98 327.8 0.5 2.4 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EJP65236.1 - 0.00085 19.9 13.7 21 6.3 0.1 7.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJP65236.1 - 0.07 13.8 11.7 1.9 9.2 0.2 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EJP65236.1 - 0.075 13.5 0.4 1.3 9.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3915 PF13054.6 EJP65236.1 - 0.56 10.2 4.2 1.7 8.6 4.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) TPR_12 PF13424.6 EJP65236.1 - 5.9 7.3 6.8 3.4 8.0 1.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 EJP65237.1 - 4.7e-46 157.2 1.1 5.5e-46 157.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP65237.1 - 3.5e-38 131.0 0.7 4.1e-38 130.8 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP65237.1 - 3.2e-12 46.7 0.6 3.8e-12 46.5 0.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP65237.1 - 0.00026 20.5 0.2 0.00053 19.5 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP65237.1 - 0.0085 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ThiF PF00899.21 EJP65237.1 - 0.21 10.9 1.3 2.6 7.3 0.0 2.1 1 1 1 2 2 2 0 ThiF family FAD_binding_4 PF01565.23 EJP65238.1 - 1.3e-22 80.1 0.0 2.3e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP65238.1 - 0.0012 18.9 0.5 0.0026 17.8 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M10 PF00413.24 EJP65239.1 - 1.2e-05 25.2 0.1 3.2e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 EJP65239.1 - 0.00044 20.5 0.0 0.00061 20.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 EJP65239.1 - 0.00059 19.1 0.0 0.00088 18.6 0.0 1.3 1 0 0 1 1 1 1 Met-zincin Reprolysin_3 PF13582.6 EJP65239.1 - 0.0015 19.0 0.0 0.0028 18.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EJP65239.1 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EJP65239.1 - 0.0024 16.9 0.1 0.0038 16.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M57 PF12388.8 EJP65239.1 - 0.0099 15.5 0.1 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M43 PF05572.13 EJP65239.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.6 EJP65239.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 EJP65239.1 - 0.099 12.2 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF4630 PF15443.6 EJP65239.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) VPS11_C PF12451.8 EJP65240.1 - 0.064 13.5 0.6 18 5.7 0.0 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Corona_nucleoca PF00937.18 EJP65240.1 - 1.5 7.8 7.4 2.7 7.0 7.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Cgr1 PF03879.14 EJP65242.1 - 2.6e-32 111.4 30.5 3e-32 111.2 30.5 1.0 1 0 0 1 1 1 1 Cgr1 family RR_TM4-6 PF06459.12 EJP65242.1 - 0.47 10.2 14.9 0.49 10.2 14.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Prismane PF03063.20 EJP65242.1 - 1.3 7.7 4.6 1.4 7.5 4.6 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family CDC27 PF09507.10 EJP65242.1 - 3.5 6.9 21.6 4.1 6.7 21.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF812 PF05667.11 EJP65243.1 - 0.00048 19.2 3.2 0.00064 18.7 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Snapin_Pallidin PF14712.6 EJP65243.1 - 0.0042 17.5 2.7 0.27 11.7 0.2 2.5 2 1 0 2 2 2 1 Snapin/Pallidin Med4 PF10018.9 EJP65243.1 - 0.015 15.0 1.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 WDCP PF15390.6 EJP65243.1 - 0.016 13.6 0.1 0.025 13.0 0.1 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family EMP24_GP25L PF01105.24 EJP65243.1 - 0.02 14.8 3.1 0.026 14.4 2.5 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MID_pPIWI_RE PF18157.1 EJP65243.1 - 0.02 15.2 3.6 0.037 14.3 0.2 2.4 2 0 0 2 2 2 0 MID domain of pPIWI_RE CENP-F_leu_zip PF10473.9 EJP65243.1 - 0.033 14.2 0.2 0.033 14.2 0.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med9 PF07544.13 EJP65243.1 - 0.053 13.6 3.2 0.27 11.3 1.0 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF5623 PF18536.1 EJP65243.1 - 0.07 13.4 2.2 0.64 10.3 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5623) DUF1664 PF07889.12 EJP65243.1 - 0.091 12.8 0.4 1.3 9.1 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4337 PF14235.6 EJP65243.1 - 0.098 12.8 0.2 0.098 12.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF4407 PF14362.6 EJP65243.1 - 0.1 12.0 6.2 0.18 11.2 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DotU PF09850.9 EJP65243.1 - 0.14 11.8 1.5 0.39 10.4 1.4 1.9 1 1 0 1 1 1 0 Type VI secretion system protein DotU IFT57 PF10498.9 EJP65243.1 - 0.16 10.9 4.2 0.29 10.0 4.2 1.3 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 EJP65243.1 - 0.17 10.7 4.6 0.058 12.3 1.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 EJP65243.1 - 0.44 9.1 5.6 0.59 8.7 5.6 1.1 1 0 0 1 1 1 0 AAA domain FUSC PF04632.12 EJP65243.1 - 0.6 8.6 7.4 0.92 8.0 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1741 PF08427.10 EJP65243.1 - 0.61 9.7 4.2 3.8 7.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1741) DHR10 PF18595.1 EJP65243.1 - 0.75 9.9 10.3 0.046 13.8 1.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain ABC_tran_Xtn PF12848.7 EJP65243.1 - 1.4 9.0 7.2 0.67 10.0 1.6 2.4 2 0 0 2 2 2 0 ABC transporter MCU PF04678.13 EJP65243.1 - 1.5 8.9 5.2 5.7 7.0 5.2 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Jnk-SapK_ap_N PF09744.9 EJP65243.1 - 3.6 7.8 9.7 0.29 11.3 1.4 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4140 PF13600.6 EJP65243.1 - 3.8 8.0 6.3 4.3 7.8 0.4 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3818 PF12825.7 EJP65244.1 - 2.4e-129 431.2 1.9 3.7e-129 430.6 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EJP65244.1 - 7.3e-39 132.7 1.7 1.5e-38 131.7 1.7 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EJP65244.1 - 2.1e-14 53.5 0.2 2.5e-13 50.0 0.0 2.8 2 1 0 2 2 2 1 PX domain PCI PF01399.27 EJP65245.1 - 2e-15 57.1 0.2 1.2e-14 54.7 0.0 2.4 3 0 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 EJP65245.1 - 3.7e-11 42.5 0.3 3.7e-11 42.5 0.3 2.1 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix DDHD PF02862.17 EJP65245.1 - 0.15 12.2 0.5 19 5.3 0.0 2.3 2 0 0 2 2 2 0 DDHD domain Pkinase PF00069.25 EJP65246.1 - 2e-76 256.8 0.0 2.6e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP65246.1 - 1e-37 129.9 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EJP65246.1 - 1.7e-17 63.5 0.2 3.1e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EJP65246.1 - 4.7e-09 36.0 0.0 2e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 EJP65246.1 - 3.9e-08 33.5 0.0 8.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 EJP65246.1 - 1.1e-05 24.4 0.0 1.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EJP65246.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EJP65246.1 - 0.037 13.0 0.1 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EJP65246.1 - 0.058 12.4 0.1 0.094 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 EJP65246.1 - 0.091 12.3 0.1 0.77 9.2 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ArfGap PF01412.18 EJP65247.1 - 6.1e-31 106.9 0.0 2.4e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EJP65247.1 - 3.8e-19 69.3 14.0 6.4e-19 68.6 14.0 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EJP65247.1 - 2.4e-13 50.5 0.1 1.2e-12 48.3 0.1 2.2 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EJP65247.1 - 0.036 14.4 4.0 0.079 13.3 0.5 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain ROS_MUCR PF05443.11 EJP65247.1 - 0.044 13.8 0.2 2.3 8.3 0.0 3.0 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein C2 PF00168.30 EJP65248.1 - 3.2e-17 62.7 0.0 8e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 EJP65248.1 - 1.3e-16 61.1 5.2 1.2e-10 41.8 0.7 3.0 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 EJP65248.1 - 1.2e-08 34.0 1.6 5.7e-08 31.8 1.1 2.0 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) CTNNB1_binding PF08347.11 EJP65248.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.9 4 0 0 4 4 4 0 N-terminal CTNNB1 binding Glyco_hydro_92 PF07971.12 EJP65249.1 - 8.5e-142 473.3 0.0 1e-141 473.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EJP65249.1 - 1.6e-65 221.4 1.6 2.6e-65 220.6 1.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain SIP1 PF04938.12 EJP65250.1 - 1.4e-06 28.2 0.0 0.0019 17.9 0.0 3.1 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) RNR_inhib PF08591.10 EJP65251.1 - 9.3e-32 110.5 0.1 5.8e-31 108.0 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor DLH PF01738.18 EJP65252.1 - 1.9e-22 79.9 0.0 3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EJP65252.1 - 0.015 14.9 0.0 0.034 13.7 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RNA12 PF10443.9 EJP65253.1 - 1.3e-147 492.1 0.1 1.7e-147 491.8 0.1 1.1 1 0 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EJP65253.1 - 0.00019 21.4 0.0 0.0071 16.3 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 EJP65253.1 - 0.0025 17.6 0.0 0.036 13.9 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 EJP65253.1 - 0.12 12.7 0.0 0.5 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain DUF3128 PF11326.8 EJP65254.1 - 5.9e-24 84.2 3.3 1e-23 83.4 3.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) HSP70 PF00012.20 EJP65255.1 - 1.6e-260 865.5 5.0 1.8e-260 865.3 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJP65255.1 - 5.8e-17 61.5 0.1 1.3e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EJP65255.1 - 0.0012 18.6 0.0 0.0055 16.5 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EJP65255.1 - 0.008 16.6 0.3 5.1 7.6 0.0 3.1 3 0 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EJP65255.1 - 0.033 13.4 0.1 0.063 12.5 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 EJP65255.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 StbA protein Pkinase PF00069.25 EJP65257.1 - 1.3e-26 93.5 0.0 2.1e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP65257.1 - 7.9e-16 58.1 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP65257.1 - 9.9e-05 22.4 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP65257.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJP65257.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-C_C PF11699.8 EJP65258.1 - 9.2e-31 105.9 0.0 1.5e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 EJP65258.1 - 6.7e-26 91.6 2.8 6.7e-26 91.6 2.8 3.8 2 2 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 EJP65258.1 - 7.3e-07 28.8 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain RNase_HII PF01351.18 EJP65259.1 - 7.4e-48 163.0 0.0 7.6e-47 159.7 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.12 EJP65260.1 - 0 1032.5 0.0 0 1032.2 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EJP65260.1 - 7e-08 32.1 0.2 1.2e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EJP65260.1 - 2.4e-06 27.7 0.0 4.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EJP65260.1 - 0.0001 22.4 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EJP65260.1 - 0.00099 19.4 0.0 0.0033 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 EJP65260.1 - 0.013 14.8 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Septin Carn_acyltransf PF00755.20 EJP65261.1 - 1.2e-209 697.8 0.0 1.1e-208 694.6 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase NACHT PF05729.12 EJP65262.1 - 7.2e-09 35.8 0.0 2.3e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EJP65262.1 - 9e-06 26.2 0.1 4.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EJP65262.1 - 0.00038 20.7 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EJP65262.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EJP65262.1 - 0.052 12.7 0.7 0.49 9.5 0.6 2.4 2 1 0 2 2 2 0 NB-ARC domain cobW PF02492.19 EJP65262.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EJP65262.1 - 0.068 13.7 0.0 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AFG1_ATPase PF03969.16 EJP65262.1 - 0.069 12.0 0.0 0.87 8.4 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_29 PF13555.6 EJP65262.1 - 0.082 12.7 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EJP65262.1 - 0.086 13.4 0.0 0.27 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain PUF PF00806.19 EJP65263.1 - 2.5e-55 181.2 13.6 4.3e-07 29.2 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat GAS PF13851.6 EJP65263.1 - 0.022 14.1 4.1 0.042 13.2 4.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 EJP65263.1 - 3.5 6.1 5.6 12 4.3 3.1 2.1 2 0 0 2 2 2 0 Macoilin family RNA_pol_Rpb2_6 PF00562.28 EJP65264.1 - 1.7e-118 396.1 0.9 2e-118 395.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EJP65264.1 - 1.8e-55 187.6 0.3 2.7e-55 187.0 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EJP65264.1 - 5.3e-33 113.3 0.6 1.3e-32 112.1 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EJP65264.1 - 1.8e-27 96.2 0.2 5e-27 94.8 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EJP65264.1 - 8.8e-22 77.2 0.2 2.8e-21 75.5 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EJP65264.1 - 2.4e-20 72.5 0.0 4.8e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EJP65264.1 - 1.3e-10 41.6 0.3 5.2e-10 39.7 0.3 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DDR_swiveling PF18427.1 EJP65264.1 - 0.082 12.9 0.3 0.25 11.4 0.3 1.8 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain Rad51 PF08423.11 EJP65265.1 - 4.6e-44 150.6 0.0 2e-43 148.5 0.0 1.8 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EJP65265.1 - 9.1e-10 38.4 0.1 2.3e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EJP65265.1 - 1.8e-05 24.4 0.6 0.00027 20.5 0.6 2.1 1 1 0 1 1 1 1 recA bacterial DNA recombination protein SUIM_assoc PF16619.5 EJP65265.1 - 0.0014 18.7 1.5 0.0014 18.7 1.5 1.8 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 ATPase PF06745.13 EJP65265.1 - 0.003 16.9 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 KaiC NACHT PF05729.12 EJP65265.1 - 0.12 12.2 0.2 0.44 10.5 0.2 1.7 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EJP65265.1 - 0.22 11.2 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TMEM119 PF15724.5 EJP65265.1 - 1.2 9.2 9.3 0.31 11.1 3.3 2.3 2 0 0 2 2 2 0 TMEM119 family zinc_ribbon_10 PF10058.9 EJP65266.1 - 0.044 13.5 0.8 3.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4279 PF14106.6 EJP65266.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) TMEM51 PF15345.6 EJP65267.1 - 8.8e-05 22.5 0.3 0.00013 21.9 0.3 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 Amidase PF01425.21 EJP65269.1 - 1.7e-112 376.7 0.1 2.3e-112 376.2 0.1 1.1 1 0 0 1 1 1 1 Amidase PRP38 PF03371.15 EJP65270.1 - 1.6e-56 190.9 0.0 1.9e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family VIT1 PF01988.19 EJP65271.1 - 2.4 8.0 5.3 5.4 6.8 0.0 2.1 2 0 0 2 2 2 0 VIT family H-kinase_dim PF02895.14 EJP65271.1 - 3.2 8.2 6.5 9.7 6.7 6.5 1.9 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Catalase PF00199.19 EJP65272.1 - 3e-157 523.6 0.0 3.8e-157 523.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 EJP65272.1 - 5.1e-43 146.3 1.2 8.6e-43 145.6 1.2 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 EJP65272.1 - 1e-15 57.7 0.0 2.2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive ECH_1 PF00378.20 EJP65274.1 - 1.3e-11 44.3 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 EJP65274.1 - 3.6e-06 27.1 0.0 8.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Formyl_trans_N PF00551.19 EJP65274.1 - 0.024 14.4 0.0 0.34 10.6 0.0 2.3 1 1 0 1 1 1 0 Formyl transferase CAP_N PF01213.19 EJP65274.1 - 0.043 13.3 0.3 0.043 13.3 0.3 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal adh_short PF00106.25 EJP65275.1 - 5.3e-30 104.3 0.0 1.1e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP65275.1 - 4.9e-24 85.2 0.0 1.2e-23 83.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase COX16 PF14138.6 EJP65276.1 - 5.1e-28 97.4 1.1 8.7e-22 77.4 0.1 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein COX16 FHA PF00498.26 EJP65277.1 - 9.7e-17 61.1 0.1 2.5e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EJP65277.1 - 6.5e-05 23.2 0.9 0.00026 21.2 0.0 2.4 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 EJP65277.1 - 0.0064 16.1 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 YhfZ C-terminal domain TolA_bind_tri PF16331.5 EJP65277.1 - 0.035 14.2 1.1 0.035 14.2 1.1 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation Syntaxin-6_N PF09177.11 EJP65277.1 - 0.3 11.7 12.5 3 8.4 8.2 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Vps51 PF08700.11 EJP65277.1 - 0.39 10.8 8.4 20 5.4 0.6 3.8 3 1 0 3 3 3 0 Vps51/Vps67 MetOD2 PF18548.1 EJP65277.1 - 2 8.6 6.6 0.57 10.3 0.5 2.8 2 1 1 3 3 3 0 Metanogen output domain 2 Clr2 PF10383.9 EJP65277.1 - 2.7 8.8 5.3 6.1 7.6 0.2 2.7 1 1 1 2 2 2 0 Transcription-silencing protein Clr2 DUF3037 PF11236.8 EJP65277.1 - 3.6 8.0 5.0 2.4 8.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Prefoldin_2 PF01920.20 EJP65277.1 - 4 7.4 9.4 0.31 11.0 1.9 2.7 2 0 0 2 2 2 0 Prefoldin subunit Romo1 PF10247.9 EJP65278.1 - 8.8e-27 93.3 15.8 1.2e-26 92.8 15.8 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EJP65278.1 - 0.025 15.0 3.4 0.031 14.6 3.4 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_5_1 PF06946.11 EJP65278.1 - 0.18 12.2 1.5 0.23 11.9 1.5 1.2 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 LapA_dom PF06305.11 EJP65278.1 - 0.24 11.2 1.0 15 5.5 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SIR2 PF02146.17 EJP65279.1 - 5e-56 189.4 0.0 7.9e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family CBFD_NFYB_HMF PF00808.23 EJP65279.1 - 1.7e-15 57.1 0.4 4.4e-15 55.7 0.4 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EJP65279.1 - 0.0074 16.7 0.1 0.0074 16.7 0.1 2.7 2 2 1 3 3 3 1 Core histone H2A/H2B/H3/H4 zf-LYAR PF08790.11 EJP65279.1 - 0.024 14.5 0.6 0.093 12.7 0.6 2.1 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger PAC2 PF09754.9 EJP65279.1 - 0.084 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 PAC2 family zf_UBZ PF18439.1 EJP65279.1 - 0.11 12.1 0.5 0.24 11.0 0.5 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger E1-E2_ATPase PF00122.20 EJP65280.1 - 4.8e-46 156.6 4.4 1.3e-45 155.1 4.4 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EJP65280.1 - 7.2e-26 91.8 0.1 1.1e-25 91.1 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EJP65280.1 - 0.0016 18.3 0.4 0.0079 16.0 0.3 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase MauE PF07291.11 EJP65280.1 - 0.15 11.8 8.6 0.087 12.6 1.9 2.8 3 0 0 3 3 3 0 Methylamine utilisation protein MauE Hydrolase_6 PF13344.6 EJP65280.1 - 0.17 12.0 0.0 0.58 10.3 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ig_mannosidase PF17753.1 EJP65281.1 - 6.9e-20 70.6 0.3 2.1e-19 69.0 0.3 1.9 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 EJP65281.1 - 6e-11 42.8 0.0 2.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EJP65281.1 - 0.0066 17.1 0.0 0.021 15.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4299 PF14132.6 EJP65281.1 - 0.037 13.5 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) Glyco_hydro_2_C PF02836.17 EJP65281.1 - 0.095 11.8 0.2 0.37 9.9 0.2 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Methyltransf_25 PF13649.6 EJP65283.1 - 0.0062 17.2 0.0 0.019 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP65283.1 - 0.032 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UBA PF00627.31 EJP65283.1 - 0.14 12.1 0.2 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain Peptidase_M43 PF05572.13 EJP65284.1 - 2.2e-05 24.4 2.1 2.8e-05 24.1 0.0 2.3 2 1 1 3 3 3 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EJP65284.1 - 2.6e-05 24.7 0.0 2.6e-05 24.7 0.0 2.8 3 1 0 3 3 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EJP65284.1 - 0.00015 21.7 0.2 0.0004 20.3 0.2 1.7 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 EJP65284.1 - 0.00032 20.9 0.3 0.00032 20.9 0.3 2.8 1 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EJP65284.1 - 0.00089 18.9 0.2 0.0021 17.7 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 EJP65284.1 - 0.0088 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 EJP65284.1 - 0.015 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like QueC PF06508.13 EJP65284.1 - 0.056 12.9 0.2 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Tup_N PF08581.10 EJP65284.1 - 0.066 13.5 8.0 1.2 9.5 1.7 2.7 2 0 0 2 2 2 0 Tup N-terminal Peptidase_M54 PF07998.11 EJP65284.1 - 0.089 12.8 0.5 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Peptidase family M54 Cep57_MT_bd PF06657.13 EJP65284.1 - 0.12 12.9 3.3 0.29 11.6 3.3 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Gln_amidase PF15644.6 EJP65284.1 - 0.21 12.6 7.5 0.061 14.4 2.7 2.5 2 0 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase AroM PF07302.11 EJP65284.1 - 0.32 10.3 1.6 0.76 9.1 1.6 1.6 1 0 0 1 1 1 0 AroM protein DUF3801 PF12687.7 EJP65284.1 - 1.8 8.6 14.7 0.072 13.2 8.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) MFS_1 PF07690.16 EJP65285.1 - 1.5e-37 129.4 36.1 1.5e-37 129.4 36.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP65285.1 - 1.6e-12 47.1 3.6 1.6e-12 47.1 3.6 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EJP65285.1 - 5.8e-06 25.0 1.9 1e-05 24.2 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EJP65285.1 - 0.99 7.7 6.6 0.067 11.6 0.2 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector DUF202 PF02656.15 EJP65285.1 - 3.8 8.0 16.5 1.3 9.6 0.3 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF202) SLC3A2_N PF16028.5 EJP65285.1 - 4.5 6.9 8.2 11 5.7 0.0 3.4 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus Cellulase PF00150.18 EJP65286.1 - 4.5e-11 42.7 0.9 4.5e-11 42.7 0.9 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RPN2_C PF18004.1 EJP65286.1 - 0.25 11.3 0.0 0.74 9.7 0.0 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Transket_pyr PF02779.24 EJP65287.1 - 4.8e-45 153.4 0.0 8.9e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EJP65287.1 - 6e-32 110.1 0.1 1.9e-31 108.5 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EJP65287.1 - 0.015 15.6 0.0 0.041 14.2 0.0 1.7 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II F-actin_cap_A PF01267.17 EJP65288.1 - 5.4e-100 334.2 0.0 6.1e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cyt-b5 PF00173.28 EJP65289.1 - 5.4e-24 84.1 0.1 7.1e-24 83.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_21 PF09976.9 EJP65289.1 - 0.06 13.1 0.6 0.092 12.4 0.2 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TFA2_Winged_2 PF18121.1 EJP65290.1 - 2.7e-19 68.6 0.0 5.5e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EJP65290.1 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain DSBA PF01323.20 EJP65291.1 - 1.1e-18 67.8 0.0 1.3e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EJP65291.1 - 0.0029 17.8 0.0 0.051 13.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin AvrRpt-cleavage PF05627.11 EJP65291.1 - 0.1 11.9 0.1 0.29 10.5 0.1 1.8 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr zf-H2C2_2 PF13465.6 EJP65292.1 - 2e-25 88.0 20.3 2.3e-08 34.1 1.0 5.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 EJP65292.1 - 9.3e-20 69.9 28.3 4e-05 23.8 2.2 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP65292.1 - 4.3e-11 42.7 25.0 0.0095 16.7 1.7 5.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP65292.1 - 3.1e-06 27.3 11.0 0.15 12.4 0.2 5.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EJP65292.1 - 0.00024 20.8 15.8 0.003 17.3 0.5 3.8 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EJP65292.1 - 0.0013 18.5 6.1 0.025 14.5 0.4 3.4 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EJP65292.1 - 0.014 15.4 22.7 0.29 11.2 0.5 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 EJP65292.1 - 0.1 13.4 6.1 2.4 8.9 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon family ADK_lid PF05191.14 EJP65292.1 - 0.31 11.0 0.1 0.31 11.0 0.1 3.6 4 1 0 4 4 4 0 Adenylate kinase, active site lid DUF3268 PF11672.8 EJP65292.1 - 0.86 10.0 5.5 0.22 11.8 0.4 2.4 2 1 1 3 3 2 0 zinc-finger-containing domain zf-met PF12874.7 EJP65292.1 - 1.4 9.4 29.4 4.8 7.7 0.4 6.6 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-CRD PF17979.1 EJP65292.1 - 1.5 8.9 11.6 4.5 7.3 3.7 2.3 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions FYVE PF01363.21 EJP65292.1 - 1.7 8.8 16.6 1.1e+02 3.0 16.6 2.7 1 1 0 1 1 1 0 FYVE zinc finger XPA_N PF01286.18 EJP65292.1 - 2.2 8.4 10.2 1.5 8.9 0.6 3.6 4 0 0 4 4 4 0 XPA protein N-terminal DUF2072 PF09845.9 EJP65292.1 - 9.4 6.5 8.0 3.5 7.9 0.3 2.9 2 1 1 3 3 3 0 Zn-ribbon containing protein VHS PF00790.19 EJP65293.1 - 1.7e-23 83.1 0.0 3.6e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EJP65293.1 - 7.8e-09 35.7 0.6 1.7e-08 34.6 0.6 1.6 1 0 0 1 1 1 1 GAT domain Flu_NS2 PF00601.19 EJP65293.1 - 0.035 14.4 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) FliX PF10768.9 EJP65293.1 - 0.45 11.0 5.9 0.18 12.3 0.6 2.6 2 0 0 2 2 2 0 Class II flagellar assembly regulator Nramp PF01566.18 EJP65294.1 - 4.9e-93 311.9 18.3 7.6e-92 308.0 18.3 2.2 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein PEMT PF04191.13 EJP65295.1 - 2.5e-29 101.8 1.7 7.3e-29 100.3 1.6 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EJP65295.1 - 0.11 12.9 0.5 3 8.3 0.0 2.7 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RXT2_N PF08595.11 EJP65296.1 - 3.5e-42 144.1 0.0 3.5e-42 144.1 0.0 2.3 3 0 0 3 3 3 1 RXT2-like, N-terminal Glyco_hydro_3 PF00933.21 EJP65297.1 - 2.2e-62 211.3 0.0 2.9e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EJP65297.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 EJP65297.1 - 0.0018 18.5 0.0 0.0082 16.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP65297.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_1 PF01979.20 EJP65298.1 - 1.3e-11 44.5 0.0 5.4e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EJP65298.1 - 1.7e-09 37.7 0.2 1.3e-07 31.5 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family NDT80_PhoG PF05224.12 EJP65299.1 - 1.1e-34 120.2 0.0 1.8e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glucosamine_iso PF01182.20 EJP65300.1 - 3.8e-21 76.0 0.0 6e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 EJP65301.1 - 1.5e-54 184.9 0.0 2.1e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EJP65301.1 - 2.6e-39 135.2 0.0 4.1e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase RTT107_BRCT_5 PF16770.5 EJP65302.1 - 1.5e-35 121.0 0.0 5.9e-33 112.7 0.0 3.7 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EJP65302.1 - 8.4e-28 96.1 1.4 1.5e-19 69.7 0.1 3.7 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 EJP65302.1 - 4.1e-24 84.8 0.0 1.8e-08 34.7 0.0 5.8 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EJP65302.1 - 1e-22 80.3 0.1 1.5e-05 25.3 0.0 5.5 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EJP65302.1 - 1.3e-09 38.2 1.0 0.047 14.0 0.2 3.6 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EJP65302.1 - 0.00032 20.7 0.0 0.31 11.1 0.1 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.12 EJP65303.1 - 3e-53 179.8 0.1 4.4e-53 179.3 0.1 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit SelB-wing_2 PF09106.11 EJP65303.1 - 0.036 14.3 0.5 2.9 8.2 0.0 3.1 3 0 0 3 3 3 0 Elongation factor SelB, winged helix NTP_transf_9 PF04248.12 EJP65303.1 - 0.096 12.6 1.1 7.2 6.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF427) Pyr_redox_2 PF07992.14 EJP65304.1 - 1.3e-47 162.4 1.9 2e-47 161.9 1.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EJP65304.1 - 1e-19 70.6 0.0 2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 EJP65304.1 - 7.8e-17 61.6 4.3 2e-15 57.1 1.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 EJP65304.1 - 2e-13 50.4 7.8 1.7e-11 44.3 5.6 2.9 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 EJP65304.1 - 5.8e-13 48.5 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske_2 PF13806.6 EJP65304.1 - 6.4e-12 45.3 0.0 0.00014 21.8 0.0 2.9 2 1 0 3 3 3 2 Rieske-like [2Fe-2S] domain Rieske PF00355.26 EJP65304.1 - 8.2e-12 44.9 0.5 8.1e-11 41.7 0.0 2.8 3 1 0 3 3 3 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 EJP65304.1 - 4.6e-05 23.2 0.4 0.46 10.4 0.1 3.4 4 0 0 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 EJP65304.1 - 0.00018 21.5 2.4 2.1 8.3 0.0 4.3 2 2 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EJP65304.1 - 0.00032 20.0 0.0 0.0008 18.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EJP65304.1 - 0.0011 18.4 0.6 1.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 EJP65304.1 - 0.008 15.3 1.2 0.046 12.8 0.3 2.4 2 1 1 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 EJP65304.1 - 0.0097 14.6 2.4 5 5.7 0.1 3.5 3 1 1 4 4 4 2 HI0933-like protein Lycopene_cycl PF05834.12 EJP65304.1 - 0.18 10.8 1.8 9.7 5.1 0.1 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein DUF2014 PF09427.10 EJP65305.1 - 1.6e-101 339.1 1.3 2.6e-101 338.4 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EJP65305.1 - 2.5e-17 62.5 0.9 5.2e-17 61.5 0.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Voldacs PF03517.13 EJP65306.1 - 0.21 11.7 1.5 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling UvrD-helicase PF00580.21 EJP65307.1 - 1.1e-62 212.4 0.0 4.9e-30 105.1 0.0 2.4 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EJP65307.1 - 8.7e-57 193.1 0.0 1.6e-56 192.2 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EJP65307.1 - 4.5e-31 108.1 0.0 8.6e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EJP65307.1 - 4.1e-14 52.1 0.0 9.4e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EJP65307.1 - 1.7e-07 31.2 0.3 0.00013 21.8 0.2 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EJP65307.1 - 3e-05 23.9 0.0 0.13 12.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EJP65307.1 - 0.00019 21.1 0.0 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EJP65307.1 - 0.042 13.6 0.1 0.042 13.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain Membralin PF09746.9 EJP65307.1 - 0.045 12.8 0.2 0.085 11.9 0.2 1.4 1 0 0 1 1 1 0 Tumour-associated protein Ceramidase_alk PF04734.13 EJP65308.1 - 2e-222 739.4 0.0 2.3e-222 739.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EJP65308.1 - 3.9e-53 179.7 0.5 6.5e-53 179.0 0.5 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Ribosomal_S7 PF00177.21 EJP65309.1 - 3.4e-24 85.2 0.0 5.3e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.26 EJP65310.1 - 7.8e-25 88.0 1.1 2.2e-22 80.1 1.1 2.8 1 1 0 1 1 1 1 Universal stress protein family RBD-FIP PF09457.10 EJP65310.1 - 0.16 11.9 0.4 0.49 10.4 0.4 1.8 1 0 0 1 1 1 0 FIP domain SPX PF03105.19 EJP65311.1 - 4.8 7.0 6.0 0.34 10.8 1.3 1.6 2 0 0 2 2 2 0 SPX domain RRM_1 PF00076.22 EJP65312.1 - 3.2e-81 267.1 3.8 5.1e-21 74.3 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EJP65312.1 - 1.2e-28 99.1 1.7 4.2e-28 97.3 0.8 2.4 3 0 0 3 3 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EJP65312.1 - 6.3e-12 45.2 0.1 0.04 13.5 0.0 5.3 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP65312.1 - 3.4e-06 27.1 1.2 0.29 11.3 0.0 5.3 4 2 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 EJP65312.1 - 7.7e-06 25.7 0.1 0.0025 17.6 0.0 3.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EJP65312.1 - 0.00057 19.9 1.6 0.82 9.8 0.1 3.4 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.6 EJP65312.1 - 0.0014 18.6 1.9 13 5.9 0.1 4.7 4 1 0 4 4 4 0 Nup53/35/40-type RNA recognition motif YflT PF11181.8 EJP65312.1 - 0.0023 18.4 5.5 0.13 12.8 0.4 3.4 3 0 0 3 3 3 1 Heat induced stress protein YflT CbiG_mid PF11761.8 EJP65312.1 - 0.015 15.4 2.3 15 5.8 0.0 3.8 4 0 0 4 4 3 0 Cobalamin biosynthesis central region NPR3 PF03666.13 EJP65312.1 - 0.46 9.2 6.7 0.78 8.5 6.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4140 PF13600.6 EJP65312.1 - 0.82 10.1 4.0 3 8.4 1.1 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DHHA1 PF02272.19 EJP65312.1 - 0.91 9.9 7.1 1.2 9.5 0.1 3.4 3 0 0 3 3 3 0 DHHA1 domain DNA_pol_phi PF04931.13 EJP65312.1 - 0.93 7.5 15.0 1.4 6.9 15.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 EJP65312.1 - 2.4 6.8 6.9 3.7 6.2 6.9 1.3 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 EJP65312.1 - 5.8 6.6 8.1 23 4.6 8.1 2.1 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.10 EJP65312.1 - 6 7.2 18.0 0.18 12.1 9.7 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HECT PF00632.25 EJP65313.1 - 9.1e-79 265.1 0.0 2.5e-78 263.7 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EJP65313.1 - 0.00022 20.7 1.0 0.0017 18.0 1.0 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif Cwf_Cwc_15 PF04889.12 EJP65313.1 - 0.71 9.6 10.7 0.023 14.5 4.0 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glyco_hydro_125 PF06824.11 EJP65314.1 - 4.8e-175 582.4 0.0 8.2e-175 581.6 0.0 1.3 1 1 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) ATG22 PF11700.8 EJP65315.1 - 8.7e-80 268.7 17.6 3.5e-79 266.7 17.7 1.7 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like NAD_binding_8 PF13450.6 EJP65316.1 - 1.7e-14 53.7 0.0 4e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EJP65316.1 - 4.8e-09 36.0 0.1 9e-07 28.5 0.0 3.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EJP65316.1 - 1.6e-06 28.2 0.1 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EJP65316.1 - 1.2e-05 25.1 0.0 9.7e-05 22.1 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP65316.1 - 0.00034 19.9 0.0 0.00065 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EJP65316.1 - 0.0033 16.3 0.0 0.018 13.9 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 EJP65316.1 - 0.037 13.3 0.0 0.078 12.2 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EJP65316.1 - 0.061 12.4 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GST_C PF00043.25 EJP65317.1 - 6.3e-14 52.0 0.0 9.2e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP65317.1 - 2.3e-08 34.1 0.0 1e-07 32.1 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EJP65317.1 - 6.8e-08 32.4 0.9 6.1e-05 23.0 0.0 2.5 1 1 1 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EJP65317.1 - 2.3e-07 31.1 0.0 4.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP65317.1 - 8.8e-07 29.1 0.0 4e-06 27.0 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EJP65317.1 - 8.6e-06 26.1 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EJP65317.1 - 0.00099 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SUKH-4 PF14435.6 EJP65317.1 - 0.02 15.0 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 SUKH-4 immunity protein SRP54 PF00448.22 EJP65318.1 - 6.5e-77 257.6 2.5 6.7e-77 257.6 1.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EJP65318.1 - 2.9e-30 104.8 6.2 2.9e-30 104.8 6.2 3.8 3 2 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 EJP65318.1 - 4e-21 75.0 0.7 1e-20 73.7 0.7 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EJP65318.1 - 9.1e-07 28.6 1.9 3.5e-06 26.7 1.2 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EJP65318.1 - 2.6e-06 27.6 0.0 6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EJP65318.1 - 1.4e-05 25.5 1.2 3e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP65318.1 - 3.3e-05 24.4 0.0 6.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EJP65318.1 - 0.00011 21.6 0.0 0.00011 21.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EJP65318.1 - 0.0013 18.5 0.1 0.0043 16.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EJP65318.1 - 0.0017 18.4 0.0 0.0062 16.6 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 EJP65318.1 - 0.003 17.2 0.2 0.033 13.9 0.0 2.6 2 0 0 2 2 2 1 Thymidylate kinase APS_kinase PF01583.20 EJP65318.1 - 0.0034 17.3 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase MeaB PF03308.16 EJP65318.1 - 0.0035 16.4 4.0 0.004 16.2 0.8 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EJP65318.1 - 0.0049 16.9 0.6 0.039 14.0 0.5 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EJP65318.1 - 0.0059 17.2 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EJP65318.1 - 0.0066 16.7 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EJP65318.1 - 0.007 16.4 0.2 0.065 13.3 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EJP65318.1 - 0.0071 16.1 0.3 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EJP65318.1 - 0.0096 16.2 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 EJP65318.1 - 0.011 15.2 0.5 2.3 7.6 0.7 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit 6PF2K PF01591.18 EJP65318.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_19 PF13245.6 EJP65318.1 - 0.023 15.0 0.0 0.059 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EJP65318.1 - 0.025 14.7 0.0 0.083 13.0 0.0 1.8 1 1 1 2 2 2 0 Torsin NTPase_1 PF03266.15 EJP65318.1 - 0.033 14.1 1.7 2.4 8.0 1.7 2.4 1 1 0 1 1 1 0 NTPase MobB PF03205.14 EJP65318.1 - 0.036 14.0 0.1 0.097 12.6 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 EJP65318.1 - 0.11 13.0 0.2 0.47 10.9 0.2 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mod_r PF07200.13 EJP65318.1 - 0.13 12.4 0.1 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Arf PF00025.21 EJP65318.1 - 0.14 11.6 0.2 0.59 9.6 0.0 2.1 3 0 0 3 3 2 0 ADP-ribosylation factor family Methyltransf_24 PF13578.6 EJP65318.1 - 0.14 13.2 0.0 0.35 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SKA2 PF16740.5 EJP65318.1 - 0.82 9.5 5.4 4.4 7.1 0.2 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DAO PF01266.24 EJP65319.1 - 6.3e-23 81.9 2.2 7.3e-23 81.7 2.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase APH PF01636.23 EJP65320.1 - 2.9e-05 24.1 0.1 4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family TMF_TATA_bd PF12325.8 EJP65321.1 - 0.026 14.7 6.3 0.67 10.2 0.1 3.3 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4094 PF13334.6 EJP65321.1 - 0.16 12.4 4.8 4.7 7.7 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) MFS_1 PF07690.16 EJP65322.1 - 3.1e-34 118.5 28.7 3.7e-34 118.2 28.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily OsmC PF02566.19 EJP65323.1 - 2.6e-16 59.9 0.0 3.6e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Lipoprotein_2 PF00921.17 EJP65323.1 - 0.022 14.3 0.5 0.029 14.0 0.5 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein RCC1 PF00415.18 EJP65325.1 - 1.4e-63 211.3 2.9 1.4e-12 48.0 0.1 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EJP65325.1 - 1.9e-35 120.0 28.6 3e-10 39.6 0.4 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Yip1 PF04893.17 EJP65326.1 - 2e-06 27.7 12.1 3.3e-05 23.7 6.3 2.5 2 0 0 2 2 2 2 Yip1 domain NTP_transf_2 PF01909.23 EJP65328.1 - 1.1e-06 28.8 0.0 2.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Zn_clus PF00172.18 EJP65329.1 - 0.00015 21.8 9.6 0.00015 21.8 9.6 2.3 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_2 PF12756.7 EJP65329.1 - 0.024 15.0 0.3 0.59 10.5 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Peptidase_S9 PF00326.21 EJP65330.1 - 0.0019 17.7 0.0 2 7.8 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase_phd PF10503.9 EJP65330.1 - 0.014 14.8 0.0 0.076 12.5 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 EJP65331.1 - 3.1e-36 125.2 2.7 4.6e-32 111.6 1.8 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EJP65331.1 - 5.9e-05 22.6 0.0 0.095 12.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EJP65331.1 - 0.097 11.5 0.1 0.31 9.8 0.0 1.7 2 0 0 2 2 2 0 Steryl acetyl hydrolase D-ser_dehydrat PF14031.6 EJP65332.1 - 3.1e-23 82.2 0.0 7.9e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EJP65332.1 - 8e-11 42.0 0.5 1.2e-10 41.4 0.5 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain dbPDZ_assoc PF16610.5 EJP65332.1 - 0.17 12.2 0.2 21 5.4 0.1 2.7 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 DHDPS PF00701.22 EJP65333.1 - 2.3e-37 128.3 0.0 2.8e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ribonuc_L-PSP PF01042.21 EJP65334.1 - 5.3e-38 129.7 0.0 5.9e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 EJP65335.1 - 8.8e-37 126.8 23.9 8.8e-37 126.8 23.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EJP65335.1 - 0.00019 20.9 0.7 0.00019 20.9 0.7 2.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LapA_dom PF06305.11 EJP65335.1 - 0.34 10.8 1.5 2.2 8.2 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Fungal_trans PF04082.18 EJP65337.1 - 2.2e-29 102.3 0.0 4.3e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65337.1 - 1.5e-07 31.4 5.2 3.1e-07 30.4 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 EJP65338.1 - 3.8e-29 101.8 2.5 3.8e-29 101.8 2.5 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EJP65338.1 - 1e-19 71.3 0.7 2.9e-19 69.8 0.7 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EJP65338.1 - 5e-19 68.3 0.0 9e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EJP65338.1 - 1.4e-13 51.3 6.9 4.9e-13 49.5 2.8 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PqqD PF05402.12 EJP65338.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Fungal_trans PF04082.18 EJP65340.1 - 1.1e-16 60.6 0.5 1e-15 57.5 0.1 2.4 1 1 1 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_1 PF00232.18 EJP65341.1 - 1.8e-145 484.9 0.0 2e-145 484.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.8 EJP65341.1 - 0.00055 19.6 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Sugar_tr PF00083.24 EJP65342.1 - 6.5e-77 259.3 22.7 7.7e-77 259.1 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP65342.1 - 2.8e-25 89.0 44.5 5.9e-21 74.8 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP65343.1 - 3.1e-79 267.0 19.3 3.8e-79 266.7 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP65343.1 - 5.4e-26 91.3 23.0 5.4e-26 91.3 23.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP65343.1 - 6.8e-06 24.8 1.3 1e-05 24.2 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RAP1 PF07218.11 EJP65344.1 - 0.22 9.8 2.8 0.26 9.5 2.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DPM3 PF08285.11 EJP65345.1 - 1.2e-35 121.6 0.1 1.3e-35 121.4 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1129 PF06570.11 EJP65345.1 - 0.22 11.0 0.8 0.3 10.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) bZIP_Maf PF03131.17 EJP65346.1 - 2.5 8.7 10.5 3.8 8.1 2.3 2.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Fungal_trans PF04082.18 EJP65347.1 - 1.3e-12 47.3 0.1 3.5e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65347.1 - 9.4e-07 28.9 12.9 1.6e-06 28.1 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hemerythrin PF01814.23 EJP65348.1 - 5.5e-13 49.7 1.2 7.7e-13 49.2 1.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain RE_HindVP PF09519.10 EJP65348.1 - 0.073 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 HindVP restriction endonuclease DUF2247 PF10004.9 EJP65348.1 - 0.088 12.6 1.9 0.13 12.1 1.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) TMPIT PF07851.13 EJP65348.1 - 0.16 11.2 1.3 0.24 10.6 1.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein CHZ PF09649.10 EJP65349.1 - 0.0019 17.6 0.7 0.0037 16.7 0.7 1.5 1 0 0 1 1 1 1 Histone chaperone domain CHZ Oxidored-like PF09791.9 EJP65350.1 - 4.8e-26 90.2 2.8 1e-25 89.1 2.8 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal IATP PF04568.12 EJP65350.1 - 0.34 11.3 2.8 1 9.8 2.8 1.9 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP TraT PF05818.12 EJP65350.1 - 1.3 8.7 3.7 2.6 7.7 3.7 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Pribosyltran PF00156.27 EJP65351.1 - 2e-05 24.2 0.0 3e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain p450 PF00067.22 EJP65354.1 - 4.6e-61 207.0 0.1 6.2e-61 206.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 EJP65355.1 - 2.2e-69 234.1 0.0 1.2e-68 231.7 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 EJP65355.1 - 8.6e-07 28.0 0.0 3.2e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 Condensation domain AMP-binding_C PF13193.6 EJP65355.1 - 0.078 14.0 0.0 0.23 12.4 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pex24p PF06398.11 EJP65356.1 - 1e-94 317.6 0.3 1.4e-94 317.1 0.3 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin WDCP PF15390.6 EJP65356.1 - 0.62 8.4 3.4 0.21 10.0 0.2 1.6 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family Arylsulfotran_2 PF14269.6 EJP65357.1 - 4.7e-25 88.6 0.9 3e-24 85.9 0.9 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EJP65357.1 - 4.1e-06 25.9 0.2 9.6e-06 24.7 0.2 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Dioxygenase_C PF00775.21 EJP65358.1 - 3e-09 36.6 0.1 5.5e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase Ribosomal_L50 PF10501.9 EJP65359.1 - 5.1e-15 55.6 0.0 9.7e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S DAHP_synth_1 PF00793.20 EJP65360.1 - 8.3e-105 349.6 0.1 9.6e-105 349.4 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.6 EJP65362.1 - 1.1e-18 66.8 0.2 1.9e-18 66.1 0.2 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly PRP4 PF08799.11 EJP65362.1 - 0.15 11.7 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Ribosomal_L13e PF01294.18 EJP65363.1 - 2.7e-67 226.1 2.2 8.7e-37 126.7 2.5 2.2 2 0 0 2 2 2 2 Ribosomal protein L13e RICTOR_V PF14668.6 EJP65364.1 - 0.0033 17.6 0.0 0.36 11.1 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 PAXX PF15384.6 EJP65364.1 - 0.032 13.9 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Arm PF00514.23 EJP65364.1 - 0.034 14.2 3.7 0.2 11.8 0.8 3.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EJP65364.1 - 0.68 10.4 12.4 0.14 12.5 2.1 4.6 4 1 1 5 5 5 0 HEAT repeats Pam16 PF03656.13 EJP65365.1 - 1.2e-29 102.9 0.2 1.4e-29 102.7 0.2 1.0 1 0 0 1 1 1 1 Pam16 BPL_N PF09825.9 EJP65366.1 - 2.5e-137 458.0 0.0 3.1e-137 457.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EJP65366.1 - 3.5e-20 72.2 0.0 5.7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Glyco_hydro_42M PF08532.10 EJP65366.1 - 0.08 12.4 0.1 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain CHCH PF06747.13 EJP65367.1 - 0.00099 19.2 10.0 0.0017 18.4 10.0 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EJP65367.1 - 0.015 15.3 4.8 0.24 11.4 0.5 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 EJP65367.1 - 0.026 14.8 2.9 0.044 14.1 2.9 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) GT-D PF08759.11 EJP65367.1 - 0.055 13.1 0.1 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold SUIM_assoc PF16619.5 EJP65367.1 - 0.081 13.0 0.1 0.081 13.0 0.1 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4629 PF15442.6 EJP65367.1 - 0.2 11.9 3.8 0.21 11.8 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Mgm101p PF06420.12 EJP65368.1 - 8.9e-83 275.9 0.0 1.4e-82 275.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Apidaecin PF00807.17 EJP65368.1 - 0.0093 16.0 2.9 0.023 14.8 2.9 1.6 1 0 0 1 1 1 1 Apidaecin TB2_DP1_HVA22 PF03134.19 EJP65369.1 - 1.6e-25 88.9 8.6 2.4e-25 88.3 8.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Meth_synt_2 PF01717.18 EJP65370.1 - 5.6e-16 58.7 0.0 6.6e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EJP65370.1 - 0.0027 17.3 0.1 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain ACD PF16671.5 EJP65370.1 - 0.066 11.5 0.1 0.11 10.8 0.1 1.3 1 0 0 1 1 1 0 Actin cross-linking domain Methyltransf_23 PF13489.6 EJP65372.1 - 1.1e-21 77.4 0.0 1.7e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP65372.1 - 1.4e-13 50.9 0.0 2.6e-12 46.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP65372.1 - 1.8e-12 47.8 0.0 4.3e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP65372.1 - 4.6e-12 46.4 0.0 9.1e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP65372.1 - 8.3e-10 39.3 0.0 5.3e-09 36.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP65372.1 - 1.8e-06 27.4 0.0 6.8e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EJP65372.1 - 0.00024 20.4 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 EJP65372.1 - 0.0012 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 EJP65372.1 - 0.0083 15.6 0.0 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 EJP65372.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 EJP65372.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 EJP65372.1 - 0.046 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EJP65372.1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aspzincin_M35 PF14521.6 EJP65374.1 - 8.3e-18 65.3 0.2 1.3e-17 64.7 0.2 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EJP65374.1 - 6.8e-14 51.5 1.4 9.2e-14 51.1 1.4 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Methyltransf_16 PF10294.9 EJP65376.1 - 7.9e-29 100.6 0.0 1.6e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EJP65376.1 - 3e-06 27.2 0.0 6.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP65376.1 - 0.0059 17.3 0.0 0.017 15.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EJP65376.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 EJP65376.1 - 0.051 12.6 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EJP65376.1 - 0.12 13.1 0.0 0.32 11.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.7 EJP65378.1 - 4.5e-16 60.1 0.0 5.4e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP65378.1 - 6.4e-06 25.6 0.7 0.00024 20.4 0.7 2.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP65378.1 - 9.6e-06 25.4 0.1 2e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EJP65378.1 - 0.00062 19.5 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF676 PF05057.14 EJP65378.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 EJP65378.1 - 0.037 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 EJP65378.1 - 0.085 12.4 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase CFEM PF05730.11 EJP65380.1 - 1.9e-14 53.5 11.8 3.6e-14 52.6 11.8 1.5 1 0 0 1 1 1 1 CFEM domain MMU163 PF17119.5 EJP65381.1 - 4.7e-70 235.6 6.3 9.7e-51 172.3 1.1 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis LSM PF01423.22 EJP65382.1 - 2e-12 46.6 0.0 3.7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EJP65382.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Hfq protein NUDIX PF00293.28 EJP65383.1 - 1.3e-18 67.3 1.1 1.6e-18 67.0 1.1 1.1 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.15 EJP65384.1 - 1.4e-48 164.9 0.0 2.5e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EJP65384.1 - 3.3e-07 30.6 0.3 8.2e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 EJP65384.1 - 0.013 15.7 1.2 0.024 14.8 0.7 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Kelch_2 PF07646.15 EJP65384.1 - 0.019 14.9 0.1 0.098 12.7 0.0 2.2 2 0 0 2 2 2 0 Kelch motif RNase_PH PF01138.21 EJP65385.1 - 4.6e-14 53.0 0.0 8e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EJP65385.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Cytochrom_C PF00034.21 EJP65387.1 - 5e-13 50.0 0.1 6.9e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EJP65387.1 - 1.8e-09 37.8 2.9 6.5e-09 36.0 2.9 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EJP65387.1 - 0.0062 16.3 0.3 0.03 14.0 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain AAA PF00004.29 EJP65388.1 - 6.5e-60 201.3 0.0 9.3e-45 152.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP65388.1 - 6.8e-16 57.8 0.0 4e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EJP65388.1 - 1.8e-12 48.0 0.3 0.0013 19.1 0.1 4.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 EJP65388.1 - 6.7e-08 32.9 0.0 0.0029 17.9 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EJP65388.1 - 2.5e-07 30.8 0.0 0.0093 16.0 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJP65388.1 - 2.7e-07 30.9 0.0 2.7e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EJP65388.1 - 1.7e-06 28.2 0.0 0.0068 16.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EJP65388.1 - 3.7e-06 26.8 0.0 0.0018 18.0 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EJP65388.1 - 5.8e-06 26.7 0.0 0.12 12.8 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Rad17 PF03215.15 EJP65388.1 - 1.4e-05 25.1 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 EJP65388.1 - 2.5e-05 24.8 0.0 0.16 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EJP65388.1 - 0.0001 22.3 0.0 0.055 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EJP65388.1 - 0.00017 20.9 0.0 0.34 10.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 EJP65388.1 - 0.00018 21.1 0.0 0.34 10.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EJP65388.1 - 0.00022 21.0 0.4 0.094 12.4 0.1 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein TniB PF05621.11 EJP65388.1 - 0.00053 19.4 0.0 0.36 10.2 0.0 2.6 3 0 0 3 3 2 1 Bacterial TniB protein AAA_17 PF13207.6 EJP65388.1 - 0.00066 20.1 0.0 1.7 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EJP65388.1 - 0.00067 19.9 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EJP65388.1 - 0.002 17.9 0.1 2.8 7.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EJP65388.1 - 0.0021 17.8 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 EJP65388.1 - 0.0026 17.9 0.0 3.1 7.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EJP65388.1 - 0.0034 17.9 0.0 4.1 7.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter TsaE PF02367.17 EJP65388.1 - 0.0056 16.7 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EJP65388.1 - 0.0061 16.4 0.6 0.21 11.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EJP65388.1 - 0.0078 16.1 0.1 2.5 8.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.26 EJP65388.1 - 0.0098 15.6 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 EJP65388.1 - 0.0099 15.2 0.0 1.3 8.3 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin Cytidylate_kin PF02224.18 EJP65388.1 - 0.012 15.4 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_25 PF13481.6 EJP65388.1 - 0.018 14.6 4.1 0.84 9.2 0.0 3.7 5 0 0 5 5 4 0 AAA domain Mg_chelatase PF01078.21 EJP65388.1 - 0.023 14.1 1.2 0.25 10.7 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EJP65388.1 - 0.023 14.4 0.0 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 EJP65388.1 - 0.07 12.3 0.0 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_19 PF13245.6 EJP65388.1 - 0.078 13.3 0.0 7.3 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EJP65388.1 - 0.094 12.6 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 NTPase RsgA_GTPase PF03193.16 EJP65388.1 - 0.13 12.1 0.1 0.5 10.2 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase LCM PF04072.14 EJP65389.1 - 1.1e-18 67.9 0.1 1.4e-18 67.5 0.1 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Ferric_reduct PF01794.19 EJP65390.1 - 8.9e-23 80.8 12.5 1.9e-22 79.7 12.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EJP65390.1 - 5.3e-06 26.6 3.1 0.036 14.2 0.0 2.9 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EJP65390.1 - 1.1e-05 25.5 0.1 0.0006 19.9 0.1 2.5 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EJP65390.1 - 0.0014 19.3 0.0 0.0039 17.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF5463 PF17551.2 EJP65390.1 - 0.16 11.9 1.3 0.52 10.3 1.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5463) PDR_assoc PF08370.11 EJP65390.1 - 0.19 11.5 1.6 0.52 10.1 1.6 1.7 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Snf7 PF03357.21 EJP65391.1 - 3.3e-33 114.7 9.5 3.9e-33 114.5 9.5 1.1 1 0 0 1 1 1 1 Snf7 DUF1513 PF07433.11 EJP65391.1 - 0.028 13.5 0.4 0.029 13.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF2096 PF09869.9 EJP65391.1 - 0.098 12.7 0.8 0.21 11.7 0.1 1.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) FUSC PF04632.12 EJP65391.1 - 9.7 4.6 7.5 3.6 6.0 4.7 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family Fructosamin_kin PF03881.14 EJP65392.1 - 4.3e-73 246.0 0.0 5.4e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EJP65392.1 - 1.5e-07 31.6 0.1 3.7e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EJP65392.1 - 0.25 10.6 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Methyltransf_4 PF02390.17 EJP65393.1 - 0.045 13.2 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.6 EJP65393.1 - 0.056 14.2 0.2 0.1 13.3 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EJP65393.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EJP65393.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PI3_PI4_kinase PF00454.27 EJP65394.1 - 1.5e-46 159.3 0.0 2.5e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAD_binding_4 PF01565.23 EJP65395.1 - 5.6e-20 71.5 0.3 1e-19 70.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP65395.1 - 7e-10 38.9 0.1 1.2e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Acetyltransf_1 PF00583.25 EJP65396.1 - 1.7e-08 34.7 0.0 3.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EJP65396.1 - 2.1e-08 35.0 0.0 4.1e-08 34.0 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJP65396.1 - 0.00075 19.7 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain vATP-synt_E PF01991.18 EJP65396.1 - 0.084 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Pkinase_fungal PF17667.1 EJP65398.1 - 1.1e-89 301.1 0.0 1.5e-89 300.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EJP65398.1 - 3.4e-06 27.2 0.0 9.9e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EJP65398.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF5052 PF16475.5 EJP65398.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) Cyanate_lyase PF02560.14 EJP65399.1 - 9e-32 108.7 0.0 1.2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EJP65399.1 - 0.00067 20.0 0.3 0.001 19.3 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EJP65399.1 - 0.016 14.8 0.0 0.033 13.9 0.0 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 RNHCP PF12647.7 EJP65400.1 - 0.029 14.3 0.1 0.045 13.7 0.1 1.3 1 0 0 1 1 1 0 RNHCP domain PPR PF01535.20 EJP65401.1 - 1.5e-20 71.9 10.4 0.00059 19.9 0.0 8.3 8 0 0 8 8 8 4 PPR repeat PPR_2 PF13041.6 EJP65401.1 - 2.4e-20 72.5 0.9 6.2e-06 26.3 0.0 7.7 5 1 3 8 8 8 4 PPR repeat family PPR_long PF17177.4 EJP65401.1 - 1.8e-07 30.7 2.8 7.6e-06 25.4 0.6 3.2 1 1 2 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EJP65401.1 - 1.6e-06 27.7 0.0 0.65 9.7 0.0 5.2 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 EJP65401.1 - 0.00048 20.1 0.2 9.6 6.4 0.0 5.1 2 1 4 6 6 6 2 Pentatricopeptide repeat domain TPR_2 PF07719.17 EJP65401.1 - 0.0009 19.2 1.0 0.93 9.8 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP65401.1 - 0.0011 19.4 7.1 0.83 10.2 0.0 5.2 3 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP65401.1 - 0.062 13.1 4.2 2 8.4 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 EJP65401.1 - 0.18 11.5 0.7 35 4.0 0.1 3.5 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 EJP65401.1 - 0.21 12.3 13.6 0.38 11.4 0.5 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJP65401.1 - 0.24 11.7 1.1 0.97 9.8 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP65401.1 - 3.2 8.8 19.7 17 6.5 0.0 8.7 8 2 2 10 10 9 0 Tetratricopeptide repeat DUF4210 PF13915.6 EJP65402.1 - 1.6e-32 111.9 0.1 4.5e-32 110.5 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EJP65402.1 - 1.8e-20 72.8 0.3 3.7e-20 71.8 0.3 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 EJP65403.1 - 0.0018 18.3 21.5 0.01 15.8 21.5 2.0 1 1 0 1 1 1 1 rRNA processing Presenilin PF01080.17 EJP65403.1 - 7.1 5.3 5.4 9.2 4.9 5.4 1.2 1 0 0 1 1 1 0 Presenilin ALC PF17527.2 EJP65403.1 - 8.5 6.0 9.7 1.1 8.9 1.0 2.2 2 0 0 2 2 2 0 Phage ALC protein RhoGAP PF00620.27 EJP65404.1 - 5.8e-46 156.1 1.5 1.3e-45 154.9 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EJP65404.1 - 1.6e-13 50.6 17.6 2.3e-09 37.4 2.2 2.5 2 0 0 2 2 2 2 LIM domain Amidohydro_3 PF07969.11 EJP65404.1 - 0.012 15.1 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family Desulfoferrod_N PF06397.12 EJP65404.1 - 0.081 12.6 8.3 2.5 7.8 0.4 3.6 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF848 PF05852.11 EJP65404.1 - 0.35 11.0 9.9 0.1 12.7 5.0 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) zf-FLZ PF04570.14 EJP65404.1 - 0.57 9.7 6.9 3.4 7.2 6.9 2.4 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 IFT20 PF14931.6 EJP65404.1 - 4.1 7.6 13.1 0.43 10.8 5.6 2.5 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Sugar_tr PF00083.24 EJP65405.1 - 5.1e-79 266.2 20.4 6.3e-79 265.9 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP65405.1 - 1.6e-21 76.7 16.7 1.6e-21 76.7 16.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4510 PF14971.6 EJP65406.1 - 0.0062 16.9 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4510) Bac_luciferase PF00296.20 EJP65408.1 - 3.4e-55 187.7 0.7 4.5e-55 187.3 0.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 EJP65409.1 - 3.4e-10 39.4 34.9 3.4e-10 39.4 34.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EJP65409.1 - 1.2e-05 25.1 4.9 1.2e-05 25.1 4.9 2.8 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 FMO-like PF00743.19 EJP65410.1 - 1.5e-17 63.2 0.0 3e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EJP65410.1 - 7.5e-11 41.8 0.0 1.6e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP65410.1 - 5.1e-10 39.4 0.0 5.1e-09 36.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP65410.1 - 1.1e-05 25.2 0.0 0.14 11.7 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EJP65410.1 - 0.00014 21.3 0.5 0.0018 17.6 0.5 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP65410.1 - 0.00024 20.4 0.0 0.0022 17.2 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EJP65410.1 - 0.037 13.3 0.6 0.073 12.3 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EJP65410.1 - 0.11 11.2 0.3 1 8.0 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 EJP65410.1 - 0.11 11.7 0.4 0.22 10.7 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EJP65410.1 - 0.15 12.1 0.5 9.7 6.2 0.1 3.0 3 1 0 3 3 3 0 FAD-NAD(P)-binding ADH_zinc_N PF00107.26 EJP65411.1 - 5.5e-15 55.5 0.5 7.9e-15 55.0 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP65411.1 - 2.3e-10 41.7 0.0 4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP65411.1 - 6.6e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain WBP-1 PF11669.8 EJP65413.1 - 0.069 13.8 0.6 0.47 11.1 0.6 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 HTH_Tnp_Tc5 PF03221.16 EJP65414.1 - 5.3e-11 42.4 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EJP65414.1 - 1.3e-05 24.9 0.0 3.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Nup54 PF13874.6 EJP65414.1 - 0.021 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 UPF0175 PF03683.13 EJP65414.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) zf-CHC2 PF01807.20 EJP65414.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger HTH_Tnp_IS630 PF01710.16 EJP65414.1 - 0.14 12.2 0.1 0.6 10.2 0.0 2.0 2 1 0 2 2 2 0 Transposase PKcGMP_CC PF16808.5 EJP65414.1 - 0.2 11.5 0.7 0.39 10.6 0.7 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAD_binding_4 PF01565.23 EJP65415.1 - 1.7e-23 82.9 0.1 3.8e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP65415.1 - 0.0066 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like YidD PF01809.18 EJP65415.1 - 0.13 12.2 0.3 0.36 10.7 0.3 1.8 1 0 0 1 1 1 0 Putative membrane protein insertion efficiency factor TANGO2 PF05742.12 EJP65416.1 - 1.7e-64 218.3 0.0 1.9e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 DUF538 PF04398.12 EJP65417.1 - 0.027 14.9 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF538 Tfb2 PF03849.14 EJP65418.1 - 4.3e-137 456.8 0.0 5.4e-137 456.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EJP65418.1 - 4.9e-21 74.9 0.8 9.6e-21 74.0 0.8 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EJP65418.1 - 0.00019 21.6 0.1 0.00046 20.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3678 PF12435.8 EJP65418.1 - 0.12 11.8 4.6 0.4 10.1 4.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) 4HBT PF03061.22 EJP65419.1 - 1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EJP65419.1 - 0.0054 17.0 0.0 0.0057 16.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 EJP65419.1 - 0.025 14.7 0.0 0.033 14.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Abhydrolase_9_N PF15420.6 EJP65420.1 - 5.8 6.9 8.8 3.4 7.6 4.3 2.5 1 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus 7TM_GPCR_Sri PF10327.9 EJP65421.1 - 0.0051 16.0 1.1 0.011 15.0 1.1 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Dpy19 PF10034.9 EJP65421.1 - 0.51 8.5 2.7 0.65 8.1 2.0 1.4 1 1 0 1 1 1 0 Q-cell neuroblast polarisation Peptidase_S10 PF00450.22 EJP65422.1 - 9.5e-69 232.8 0.0 1.6e-68 232.1 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Nitroreductase PF00881.24 EJP65423.1 - 2.1e-12 47.4 0.0 2.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF5072 PF16807.5 EJP65423.1 - 0.0063 16.6 0.0 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5072) TM1586_NiRdase PF14512.6 EJP65423.1 - 0.008 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative TM nitroreductase HsbA PF12296.8 EJP65425.1 - 2.1e-22 79.8 5.5 2.1e-22 79.8 5.5 1.7 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF948 PF06103.11 EJP65425.1 - 0.022 15.0 0.7 0.17 12.1 0.7 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UPF0253 PF06786.12 EJP65425.1 - 0.092 13.0 0.8 1.4 9.3 0.0 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0253) LMP PF04778.12 EJP65425.1 - 0.19 11.6 0.4 2.5 8.0 0.0 2.1 2 1 0 2 2 2 0 LMP repeated region CDK2AP PF09806.9 EJP65425.1 - 0.89 9.6 5.7 0.33 11.0 3.1 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein MFS_1 PF07690.16 EJP65426.1 - 1e-15 57.6 34.5 1e-15 57.6 34.5 2.3 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF5391 PF17369.2 EJP65426.1 - 0.26 11.3 5.1 0.13 12.3 2.2 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5391) Sugar_tr PF00083.24 EJP65426.1 - 0.45 9.3 29.8 38 3.0 29.6 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter Bac_export_2 PF01312.19 EJP65426.1 - 1.3 8.1 9.1 2 7.6 5.3 2.6 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family Sugar_tr PF00083.24 EJP65430.1 - 9.6e-45 153.3 14.7 1.3e-44 152.9 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP65430.1 - 1.1e-15 57.5 20.5 1.8e-15 56.7 20.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Pho86 PF11124.8 EJP65431.1 - 0.11 12.0 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Fungal_trans PF04082.18 EJP65432.1 - 5.9e-11 41.9 0.0 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65432.1 - 4.5e-09 36.3 10.0 8.4e-09 35.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EJP65433.1 - 3.3e-41 141.4 43.1 8.3e-41 140.1 43.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3382 PF11862.8 EJP65433.1 - 0.15 12.4 0.2 0.15 12.4 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) DUF2681 PF10883.8 EJP65433.1 - 1.1 9.7 2.2 38 4.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) HET PF06985.11 EJP65434.1 - 5.5e-10 39.8 1.5 3.8e-07 30.5 0.0 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 EJP65435.1 - 2.3e-88 297.1 21.3 3e-88 296.7 21.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP65435.1 - 3.1e-09 36.2 39.6 1e-07 31.3 10.6 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EJP65436.1 - 1.9e-43 148.8 40.8 3.5e-40 138.0 40.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP65436.1 - 7.9e-20 70.8 20.9 1.1e-19 70.4 20.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EJP65436.1 - 8.1e-15 54.6 9.0 8.1e-15 54.6 9.0 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter PALP PF00291.25 EJP65437.1 - 1.1e-30 107.1 0.0 3.8e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 EJP65437.1 - 2.2e-07 31.4 0.0 3.1e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain FA_desaturase PF00487.24 EJP65438.1 - 9.8e-25 87.8 17.9 2.5e-24 86.5 17.9 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EJP65438.1 - 3.7e-07 30.4 0.0 1.8e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Ribonuc_2-5A PF06479.12 EJP65439.1 - 2.1e-44 150.7 0.0 4.5e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EJP65439.1 - 3.3e-40 138.1 0.0 1.1e-38 133.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP65439.1 - 5.9e-20 71.6 0.0 6.7e-19 68.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EJP65439.1 - 7.2e-07 28.8 0.6 0.012 15.5 0.0 3.8 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 EJP65439.1 - 3.3e-05 23.6 0.6 0.0027 17.3 0.2 3.1 3 1 1 4 4 4 2 PQQ-like domain Kdo PF06293.14 EJP65439.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP65439.1 - 0.009 16.0 0.8 0.27 11.1 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EJP65439.1 - 0.34 9.7 8.6 0.1 11.4 2.6 2.6 2 1 0 2 2 2 0 Fungal protein kinase eIF2A PF08662.11 EJP65440.1 - 1.3e-39 136.2 1.7 7.9e-37 127.0 0.2 4.0 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EJP65440.1 - 0.00097 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EJP65440.1 - 0.007 17.2 0.0 7.1 7.7 0.0 4.3 3 1 0 3 3 3 1 WD domain, G-beta repeat IKI3 PF04762.12 EJP65440.1 - 0.22 9.5 0.8 1.1 7.1 0.0 2.4 3 0 0 3 3 3 0 IKI3 family Cpn60_TCP1 PF00118.24 EJP65441.1 - 4.7e-142 474.1 11.7 5.4e-142 473.9 11.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 EJP65441.1 - 0.015 15.4 0.2 0.035 14.3 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 EJP65441.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat RabGAP-TBC PF00566.18 EJP65443.1 - 3.6e-27 95.4 0.0 5.2e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EJP65443.1 - 5.8e-08 31.5 0.1 9e-08 30.8 0.1 1.2 1 0 0 1 1 1 1 SBE2, cell-wall formation Stathmin PF00836.19 EJP65443.1 - 0.17 11.9 6.9 3.5 7.6 2.9 2.5 2 0 0 2 2 2 0 Stathmin family SWIB PF02201.18 EJP65444.1 - 2.7e-28 97.7 0.2 6.1e-28 96.5 0.2 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EJP65444.1 - 1.1e-10 41.3 0.2 1.1e-10 41.3 0.2 2.3 3 0 0 3 3 3 1 DEK C terminal domain Imm32 PF15566.6 EJP65444.1 - 0.024 14.5 0.0 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 32 zf-C3HC4_3 PF13920.6 EJP65445.1 - 8.3e-05 22.4 10.2 8.3e-05 22.4 10.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF3445 PF11927.8 EJP65446.1 - 3.3e-75 252.6 0.0 3.8e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) adh_short PF00106.25 EJP65448.1 - 2.4e-39 134.9 2.3 3.1e-39 134.4 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP65448.1 - 1.6e-30 106.4 0.8 2.1e-30 106.0 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EJP65448.1 - 0.00023 20.6 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 EJP65448.1 - 0.03 14.3 0.3 0.055 13.5 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EJP65448.1 - 0.03 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EJP65448.1 - 0.033 14.4 0.1 0.076 13.3 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 EJP65448.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NatB_MDM20 PF09797.9 EJP65449.1 - 3e-53 181.1 1.5 5e-53 180.4 1.5 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit ABC_tran PF00005.27 EJP65449.1 - 1.5e-51 174.5 0.0 8.1e-30 104.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP65449.1 - 1.5e-12 47.7 1.4 1.5e-12 47.7 1.4 2.5 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EJP65449.1 - 5.5e-09 35.8 0.9 0.00027 20.4 0.1 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EJP65449.1 - 5.9e-05 22.3 0.1 0.16 11.0 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EJP65449.1 - 0.00013 22.0 0.1 0.041 14.0 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EJP65449.1 - 0.00041 20.6 0.1 0.033 14.4 0.1 3.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EJP65449.1 - 0.011 15.7 0.1 0.26 11.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EJP65449.1 - 0.016 14.9 0.4 7.7 6.3 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP65449.1 - 0.019 15.4 3.5 0.24 11.7 0.7 3.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 EJP65449.1 - 0.023 14.5 0.0 9 6.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EJP65449.1 - 0.028 14.9 0.7 4 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain TPR_19 PF14559.6 EJP65449.1 - 0.03 14.8 2.4 0.1 13.1 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Dynamin_N PF00350.23 EJP65449.1 - 0.05 13.7 0.2 0.76 9.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 EJP65449.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EJP65449.1 - 0.15 12.2 0.1 0.66 10.0 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Terminase_4 PF05119.12 EJP65450.1 - 0.0017 18.8 1.2 0.014 15.8 0.1 2.6 2 0 0 2 2 2 1 Phage terminase, small subunit Ras PF00071.22 EJP65451.1 - 2e-64 216.1 0.0 2.4e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP65451.1 - 4.3e-34 117.3 0.1 6.4e-34 116.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP65451.1 - 2.3e-13 50.0 0.0 2.7e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EJP65451.1 - 6.9e-06 25.7 0.0 1.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EJP65451.1 - 0.00019 20.9 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJP65451.1 - 0.0028 17.7 0.0 0.0053 16.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP65451.1 - 0.0084 16.0 0.2 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EJP65451.1 - 0.046 13.2 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EJP65451.1 - 0.1 12.9 0.1 0.74 10.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 EJP65451.1 - 0.14 11.7 0.0 0.68 9.4 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 EJP65451.1 - 0.14 12.6 0.0 8.3 6.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_61 PF03443.14 EJP65452.1 - 3.3e-52 177.4 0.0 5.8e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cpn10 PF00166.21 EJP65453.1 - 8.5e-30 102.7 0.0 1.2e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.25 EJP65454.1 - 6.5e-47 160.1 0.1 3.6e-42 144.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP65454.1 - 3.3e-20 72.5 0.0 7.9e-20 71.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EJP65454.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EJP65454.1 - 0.016 14.2 0.0 0.034 13.1 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain RPN2_C PF18004.1 EJP65454.1 - 0.071 13.0 7.0 0.15 11.9 7.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Kinase-like PF14531.6 EJP65454.1 - 0.076 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EJP65454.1 - 0.14 11.7 0.0 3.6 7.1 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2781 PF10914.8 EJP65454.1 - 0.23 11.8 0.0 0.39 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Dicty_REP PF05086.12 EJP65454.1 - 0.34 8.8 4.9 0.49 8.3 4.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein YABBY PF04690.13 EJP65454.1 - 2.6 8.6 5.5 5.9 7.4 5.5 1.5 1 0 0 1 1 1 0 YABBY protein Pkinase PF00069.25 EJP65455.1 - 5.3e-21 75.2 0.0 9.4e-10 38.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP65455.1 - 2.2e-10 40.2 0.5 6.6e-05 22.3 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EJP65455.1 - 0.002 17.5 0.0 0.91 8.8 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 EJP65455.1 - 0.046 13.6 0.6 0.29 11.0 0.3 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EJP65455.1 - 0.055 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-AN1 PF01428.16 EJP65456.1 - 4.7e-13 49.0 4.5 4.7e-13 49.0 4.5 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EJP65456.1 - 0.34 11.3 6.3 0.17 12.3 4.2 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Tannase PF07519.11 EJP65457.1 - 3.8e-89 299.8 0.7 4.5e-89 299.5 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EJP65457.1 - 0.00057 19.4 0.2 0.36 10.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EJP65457.1 - 0.0014 18.3 0.1 0.064 12.9 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP65457.1 - 0.05 12.9 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Acyl-CoA_dh_1 PF00441.24 EJP65458.1 - 2.4e-13 50.6 0.0 1.8e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 EJP65458.1 - 2.1e-10 40.7 0.0 6.2e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 EJP65458.1 - 6.3e-10 39.1 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EJP65458.1 - 0.0024 18.1 0.0 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain A_deaminase PF00962.22 EJP65460.1 - 2.6e-23 82.9 0.0 5.7e-22 78.5 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase NmrA PF05368.13 EJP65461.1 - 0.0042 16.7 0.0 0.52 9.8 0.0 2.6 3 0 0 3 3 3 2 NmrA-like family Pkinase PF00069.25 EJP65463.1 - 5.1e-10 39.2 0.0 1.8e-08 34.1 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP65463.1 - 1.3e-06 27.9 0.0 0.00075 18.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP65463.1 - 0.0034 16.2 0.0 0.0048 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EJP65463.1 - 0.0038 17.2 0.0 0.0094 15.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP65463.1 - 0.0047 16.3 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJP65463.1 - 0.022 14.1 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ING PF12998.7 EJP65464.1 - 2.8e-22 79.2 4.0 4.7e-22 78.5 4.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding TFIIA PF03153.13 EJP65464.1 - 2.3e-05 24.6 5.5 3.2e-05 24.1 5.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PHD PF00628.29 EJP65464.1 - 0.00017 21.4 9.5 0.00017 21.4 9.5 1.7 2 0 0 2 2 2 1 PHD-finger DUF2552 PF10827.8 EJP65464.1 - 0.058 13.6 0.7 0.14 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) zf-HC5HC2H PF13771.6 EJP65464.1 - 0.076 13.3 1.0 0.17 12.2 1.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 EJP65464.1 - 1.1 9.7 6.6 2 8.8 6.6 1.5 1 0 0 1 1 1 0 Ring finger domain Methyltransf_16 PF10294.9 EJP65465.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Complex1_LYR_2 PF13233.6 EJP65466.1 - 3.1e-19 69.5 0.1 4e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EJP65466.1 - 9.6e-12 44.8 0.1 1.6e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EJP65466.1 - 0.0014 19.2 0.1 0.0022 18.5 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like HA2 PF04408.23 EJP65467.1 - 9.5e-16 58.0 0.1 9.5e-16 58.0 0.1 2.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EJP65467.1 - 1.6e-11 44.4 0.1 5.9e-11 42.6 0.1 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EJP65467.1 - 1.1e-10 41.8 0.0 3.2e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP65467.1 - 0.0001 22.2 0.0 0.00034 20.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJP65467.1 - 0.0029 17.9 0.0 0.0079 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain V-SNARE_C PF12352.8 EJP65468.1 - 0.4 11.0 7.3 0.19 12.0 2.3 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Choline_kinase PF01633.20 EJP65469.1 - 2.9e-50 170.8 0.0 4.9e-49 166.8 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EJP65469.1 - 3.2e-08 33.8 0.1 7e-08 32.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EJP65469.1 - 8e-07 28.7 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EJP65469.1 - 0.0044 15.9 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) CPSF_A PF03178.15 EJP65470.1 - 6e-69 232.8 0.0 1.5e-68 231.5 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EJP65470.1 - 2.7e-12 46.1 0.0 4.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BDHCT_assoc PF16204.5 EJP65470.1 - 0.3 10.7 1.0 0.54 9.9 1.0 1.3 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Ank_2 PF12796.7 EJP65471.1 - 5.6e-20 71.7 0.0 2.1e-10 41.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP65471.1 - 7.8e-18 64.6 0.2 3.6e-08 33.8 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP65471.1 - 1.3e-16 60.4 3.1 6.9e-08 32.6 0.2 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP65471.1 - 8.8e-15 53.4 0.1 0.00017 21.8 0.0 5.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EJP65471.1 - 5.6e-14 51.9 0.0 0.00011 22.5 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.12 EJP65471.1 - 3.1e-08 33.7 0.4 2.2e-07 31.0 0.1 2.5 3 0 0 3 3 3 1 NACHT domain PNP_UDP_1 PF01048.20 EJP65471.1 - 4.3e-05 22.9 0.0 0.00019 20.8 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily KAP_NTPase PF07693.14 EJP65471.1 - 0.0019 17.5 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain NIF PF03031.18 EJP65471.1 - 0.038 13.7 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Mg_chelatase PF01078.21 EJP65471.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NAD_binding_10 PF13460.6 EJP65472.1 - 6.1e-12 45.8 0.0 1.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EJP65472.1 - 1.4e-09 37.8 0.0 2.7e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family XdhC_CoxI PF02625.16 EJP65472.1 - 0.046 13.9 0.3 0.23 11.7 0.3 2.2 1 1 0 1 1 1 0 XdhC and CoxI family NAD_binding_4 PF07993.12 EJP65472.1 - 0.072 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Alginate_lyase2 PF08787.11 EJP65473.1 - 2.6e-44 151.8 0.0 3e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Flavoprotein PF02441.19 EJP65474.1 - 1.4e-15 57.4 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 EJP65474.1 - 0.00034 21.1 0.2 0.21 12.2 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Pribosyltran_N PF13793.6 EJP65475.1 - 4.6e-43 145.8 0.4 1.2e-42 144.5 0.1 1.9 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EJP65475.1 - 1.4e-41 142.5 1.1 4.3e-35 121.4 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EJP65475.1 - 1.2e-15 57.4 0.4 2.4e-15 56.4 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EJP65475.1 - 0.0025 17.3 0.1 0.004 16.6 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Acetyltransf_1 PF00583.25 EJP65476.1 - 1.3e-07 31.9 0.0 1.8e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP65476.1 - 4.9e-05 23.7 0.0 7.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP65476.1 - 0.00028 20.8 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP65476.1 - 0.0051 16.8 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein FtsJ PF01728.19 EJP65477.1 - 1.7e-61 207.4 0.0 2.3e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Glyco_trans_2_3 PF13632.6 EJP65478.1 - 1.2e-52 178.7 3.0 1.2e-52 178.7 3.0 1.8 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EJP65478.1 - 3.4e-05 23.7 0.0 7.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EJP65478.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EJP65478.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 EJP65479.1 - 3.6e-16 59.1 3.0 6.3e-16 58.3 3.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fasciclin PF02469.22 EJP65480.1 - 1.6e-41 141.5 0.0 5.7e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain RRM_1 PF00076.22 EJP65481.1 - 5.5e-15 54.9 0.0 7.8e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MARVEL PF01284.23 EJP65483.1 - 6.2e-26 91.1 16.2 7.7e-26 90.8 16.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain Colicin_V PF02674.16 EJP65483.1 - 0.069 13.1 10.9 0.095 12.7 10.9 1.2 1 0 0 1 1 1 0 Colicin V production protein DUF4064 PF13273.6 EJP65483.1 - 0.11 12.8 16.7 0.11 12.7 14.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) S_4TM PF18159.1 EJP65483.1 - 0.18 11.1 3.0 0.27 10.5 3.0 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Amastin PF07344.11 EJP65483.1 - 0.27 11.1 8.3 0.31 10.9 5.6 2.0 1 1 1 2 2 2 0 Amastin surface glycoprotein OAD_gamma PF04277.13 EJP65483.1 - 0.93 10.1 4.6 19 5.9 2.1 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4870 PF09685.10 EJP65483.1 - 8 6.6 13.5 2.2 8.4 10.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Glyco_hydro_18 PF00704.28 EJP65484.1 - 2.2e-20 73.6 3.0 4.5e-20 72.6 3.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Acetyltransf_1 PF00583.25 EJP65485.1 - 6.3e-14 52.2 0.0 8.2e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP65485.1 - 5.2e-08 32.9 0.0 1.5e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP65485.1 - 1.3e-07 32.0 0.0 2.9e-07 30.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP65485.1 - 1.1e-06 28.5 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EJP65485.1 - 0.00031 20.8 0.0 0.00064 19.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EJP65485.1 - 0.0039 17.3 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EJP65485.1 - 0.0062 17.2 0.0 0.0086 16.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1279 PF06916.13 EJP65488.1 - 2e-24 85.9 0.1 4.8e-24 84.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) pKID PF02173.17 EJP65490.1 - 0.00048 19.5 3.3 0.2 11.1 0.0 2.7 3 0 0 3 3 3 2 pKID domain Y_phosphatase3 PF13350.6 EJP65491.1 - 4.2e-45 154.5 0.0 4.9e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EJP65491.1 - 0.0014 18.2 0.0 0.0019 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EJP65491.1 - 0.0036 16.9 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Amidohydro_3 PF07969.11 EJP65492.1 - 2.5e-64 218.5 7.7 4.1e-64 217.8 7.5 1.4 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 EJP65492.1 - 0.00079 18.8 0.2 0.15 11.3 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Acyl_transf_3 PF01757.22 EJP65493.1 - 9.5e-41 140.0 31.3 9.5e-41 140.0 31.3 1.4 2 0 0 2 2 2 1 Acyltransferase family DUF4604 PF15377.6 EJP65494.1 - 0.039 14.4 8.2 0.047 14.1 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Nop53 PF07767.11 EJP65494.1 - 0.15 11.5 13.8 0.18 11.2 13.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PGA2 PF07543.12 EJP65494.1 - 0.47 10.4 9.6 0.61 10.1 9.6 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 ALAD PF00490.21 EJP65495.1 - 4.1e-120 400.7 0.0 4.8e-120 400.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Podoplanin PF05808.11 EJP65497.1 - 0.02 15.0 0.4 0.03 14.4 0.4 1.2 1 0 0 1 1 1 0 Podoplanin Fungal_trans PF04082.18 EJP65498.1 - 1e-23 83.7 0.2 1.6e-23 83.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AP_endonuc_2 PF01261.24 EJP65499.1 - 6.5e-35 120.5 0.0 2.3e-34 118.7 0.0 1.8 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 EJP65499.1 - 0.0024 17.6 0.2 0.01 15.6 0.0 2.2 3 0 0 3 3 3 1 AP endonuclease family 2 C terminus Metallophos PF00149.28 EJP65500.1 - 4.7e-12 46.8 0.1 6.7e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP65500.1 - 8e-09 35.9 0.4 7.4e-08 32.8 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NMO PF03060.15 EJP65502.1 - 8.2e-53 179.9 0.3 8.5e-52 176.6 0.3 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EJP65502.1 - 7.3e-12 44.9 0.5 9.5e-06 24.8 0.0 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EJP65502.1 - 0.00037 19.6 0.1 0.00058 19.0 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NIL PF09383.10 EJP65502.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 NIL domain His_biosynth PF00977.21 EJP65502.1 - 0.059 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 EJP65502.1 - 0.081 12.1 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 EJP65502.1 - 0.14 11.3 0.4 0.85 8.8 0.1 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF561 PF04481.12 EJP65502.1 - 0.31 10.2 2.7 2.7 7.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF561) LOR PF04525.12 EJP65503.1 - 2.1e-15 56.8 0.0 2.8e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related Glycoamylase PF10091.9 EJP65503.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative glucoamylase Fungal_trans PF04082.18 EJP65504.1 - 1.2e-08 34.3 1.4 3.6e-08 32.8 1.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EJP65504.1 - 2.6e-07 30.7 9.7 0.0067 16.8 0.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP65504.1 - 9.5e-06 25.8 2.1 9.5e-06 25.8 2.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP65504.1 - 1.8e-05 25.2 9.1 0.082 13.8 4.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP65504.1 - 0.019 15.3 1.0 0.17 12.2 1.4 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EJP65504.1 - 2.7 8.0 6.0 3.4 7.7 2.5 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ferric_reduct PF01794.19 EJP65506.1 - 7.4e-21 74.6 16.9 2.1e-20 73.1 16.9 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EJP65506.1 - 3e-07 30.5 0.1 0.00098 19.2 0.1 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 EJP65506.1 - 7.1e-07 29.5 0.5 0.0051 16.9 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EJP65506.1 - 0.41 11.3 1.4 4.1 8.1 0.2 2.5 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4293 PF14126.6 EJP65506.1 - 0.93 9.7 11.2 0.8 9.9 8.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Alpha-amylase PF00128.24 EJP65507.1 - 2.6e-57 194.9 0.7 4.2e-56 190.9 0.7 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EJP65507.1 - 0.00069 17.9 0.2 0.0016 16.8 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 70 hDGE_amylase PF14701.6 EJP65507.1 - 0.0024 17.0 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Amidase_2 PF01510.25 EJP65507.1 - 0.0074 16.7 0.4 0.017 15.6 0.1 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-L-alanine amidase DUF1966 PF09260.11 EJP65507.1 - 0.0084 16.4 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Aminotran_5 PF00266.19 EJP65507.1 - 0.082 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V PhyH PF05721.13 EJP65508.1 - 3e-09 37.4 0.1 7.8e-09 36.1 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_16 PF10294.9 EJP65509.1 - 2.4e-13 50.2 0.0 3.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EJP65509.1 - 0.0055 16.1 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CPSF100_C PF13299.6 EJP65510.1 - 3 8.0 11.6 2.3 8.4 0.1 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Beta-lactamase PF00144.24 EJP65511.1 - 6.4e-45 153.8 1.2 1.5e-44 152.6 1.4 1.5 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 EJP65511.1 - 3.9e-16 59.4 0.0 6.8e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF5599 PF18141.1 EJP65511.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5599) Copper-fist PF00649.18 EJP65512.1 - 1.6e-19 69.1 0.7 3.7e-19 67.9 0.7 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain Surp PF01805.20 EJP65513.1 - 1.8e-07 31.1 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Surp module DAO PF01266.24 EJP65514.1 - 5.9e-32 111.6 4.3 7.2e-32 111.3 4.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EJP65514.1 - 6e-06 26.3 0.2 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EJP65514.1 - 1.4e-05 25.2 0.0 5e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP65514.1 - 6.7e-05 22.3 0.0 0.0013 18.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP65514.1 - 0.018 14.2 0.0 0.081 12.0 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 EJP65514.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TBP PF00352.21 EJP65515.1 - 1.4e-67 223.6 0.1 7e-33 112.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EJP65515.1 - 0.00012 22.2 0.0 0.22 11.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EJP65515.1 - 0.13 12.1 0.1 0.67 9.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ETF_QO PF05187.13 EJP65516.1 - 1.7e-48 163.0 1.2 2.9e-48 162.3 1.2 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EJP65516.1 - 6.4e-08 32.6 0.8 0.00018 21.2 0.6 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP65516.1 - 4e-07 30.2 0.0 1.5e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP65516.1 - 4.9e-06 25.9 1.0 0.0019 17.4 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EJP65516.1 - 0.00011 21.6 0.0 0.0003 20.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP65516.1 - 0.00018 20.9 0.0 0.00046 19.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EJP65516.1 - 0.00074 18.9 0.2 0.0011 18.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EJP65516.1 - 0.0009 19.3 0.2 0.0048 16.9 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EJP65516.1 - 0.0014 17.5 0.7 0.002 16.9 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EJP65516.1 - 0.0015 19.0 0.0 0.96 10.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP65516.1 - 0.0044 16.3 0.3 0.0069 15.7 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 EJP65516.1 - 0.0096 16.5 1.0 0.028 15.0 1.0 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 EJP65516.1 - 0.028 13.7 0.1 0.061 12.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 EJP65516.1 - 0.03 13.6 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EJP65516.1 - 0.044 13.1 0.1 0.083 12.2 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP65516.1 - 0.071 12.1 0.3 0.11 11.6 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 EJP65516.1 - 0.099 11.5 0.1 1.5 7.6 0.2 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Fer4_2 PF12797.7 EJP65516.1 - 0.15 12.2 0.7 0.46 10.7 0.7 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain K_oxygenase PF13434.6 EJP65516.1 - 0.19 10.8 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EJP65516.1 - 0.19 10.7 0.2 0.33 10.0 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.16 EJP65517.1 - 2e-12 46.7 32.2 2e-11 43.5 20.3 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily FAD_binding_2 PF00890.24 EJP65518.1 - 8.2e-93 311.7 0.1 9.4e-93 311.5 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EJP65518.1 - 7e-06 26.2 0.2 2.5e-05 24.4 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EJP65518.1 - 4.3e-05 22.9 0.0 8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EJP65518.1 - 6.7e-05 22.3 0.2 0.0021 17.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP65518.1 - 0.0001 22.0 1.4 0.00018 21.2 0.1 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP65518.1 - 0.00028 19.7 2.0 0.0062 15.3 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EJP65518.1 - 0.00066 18.9 0.2 0.00066 18.9 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EJP65518.1 - 0.00067 19.0 0.1 0.0015 17.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EJP65518.1 - 0.0027 17.1 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EJP65518.1 - 0.049 12.9 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_PK PF05891.12 EJP65519.1 - 5.7e-71 238.5 0.0 6.6e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EJP65519.1 - 7e-05 23.5 0.0 0.00015 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP65519.1 - 0.00018 21.4 0.0 0.00069 19.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP65519.1 - 0.0015 19.3 0.0 0.0026 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EJP65519.1 - 0.0031 16.8 0.0 0.0056 16.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 EJP65519.1 - 0.024 15.3 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 EJP65520.1 - 2e-41 139.2 13.3 4.7e-06 27.2 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP65520.1 - 3.6e-09 36.8 0.7 0.21 11.9 0.0 5.3 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EJP65520.1 - 7.7e-09 35.3 0.1 1.5e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP65520.1 - 1e-08 34.8 0.0 2.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EJP65520.1 - 0.017 13.8 0.4 18 3.8 0.0 3.9 2 1 2 4 4 4 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EJP65520.1 - 0.027 14.0 0.7 13 5.2 0.0 2.8 2 1 0 2 2 2 0 PQQ-like domain F-box_4 PF15966.5 EJP65520.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 F-box DUF2502 PF10697.9 EJP65522.1 - 0.1 13.0 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) Methyltransf_2 PF00891.18 EJP65523.1 - 1.8e-13 50.3 0.0 3.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 EJP65523.1 - 0.0084 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP65523.1 - 0.017 15.8 0.0 0.034 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EJP65523.1 - 0.017 15.8 0.0 0.043 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EJP65523.1 - 0.046 13.2 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase 4HBT_3 PF13622.6 EJP65524.1 - 2.6e-36 126.1 0.4 3.1e-36 125.9 0.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily PS-DH PF14765.6 EJP65524.1 - 0.039 13.2 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Polyketide synthase dehydratase SLAC1 PF03595.17 EJP65525.1 - 1.3e-75 254.7 44.6 1.5e-75 254.5 44.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Anophelin PF10731.9 EJP65525.1 - 0.3 11.0 1.7 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito HRXXH PF13933.6 EJP65526.1 - 4.8e-107 357.1 0.0 5.5e-107 356.9 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 EJP65526.1 - 2.7e-05 24.8 0.0 4.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EJP65526.1 - 0.055 12.3 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Deuterolysin metalloprotease (M35) family E1-E2_ATPase PF00122.20 EJP65528.1 - 9.6e-18 64.3 0.0 2.7e-17 62.9 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EJP65528.1 - 4.6e-14 53.2 7.1 7.8e-09 36.1 3.7 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EJP65528.1 - 0.0026 17.5 0.1 0.051 13.3 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase G0-G1_switch_2 PF15103.6 EJP65528.1 - 0.0055 17.1 0.8 3.2 8.2 0.9 2.5 2 0 0 2 2 2 2 G0/G1 switch protein 2 Cation_ATPase PF13246.6 EJP65528.1 - 0.012 15.7 2.4 0.042 13.9 0.0 2.6 3 0 0 3 3 3 0 Cation transport ATPase (P-type) S6PP PF05116.13 EJP65528.1 - 0.1 12.1 0.2 8.9 5.8 0.0 3.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Plasmodium_HRP PF05403.11 EJP65529.1 - 1e-07 32.0 3.4 1.9e-07 31.1 3.4 1.4 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) Csd3_N PF18059.1 EJP65529.1 - 0.074 13.6 1.9 0.13 12.8 0.1 2.3 3 0 0 3 3 3 0 Csd3 N-terminal CDP-OH_P_transf PF01066.21 EJP65532.1 - 8.6e-13 48.9 0.4 8.6e-13 48.9 0.4 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-C2HC5 PF06221.13 EJP65533.1 - 3.9e-21 74.8 5.6 6.2e-21 74.1 5.6 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type HEPN_SAV2148 PF18725.1 EJP65533.1 - 0.013 14.9 0.4 0.031 13.7 0.0 1.7 2 0 0 2 2 2 0 SAV2148-like HEPN FXR_C1 PF16096.5 EJP65533.1 - 0.017 15.3 1.2 0.079 13.2 1.2 2.2 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Ldh_1_C PF02866.18 EJP65534.1 - 4e-44 150.5 0.0 6.3e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EJP65534.1 - 5.5e-43 146.4 0.1 1.1e-42 145.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EJP65534.1 - 0.0091 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 EJP65534.1 - 0.074 12.4 0.0 0.62 9.4 0.0 2.4 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 EJP65534.1 - 0.086 13.3 0.0 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 14-3-3 PF00244.20 EJP65536.1 - 0.1 12.1 0.1 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 14-3-3 protein Seryl_tRNA_N PF02403.22 EJP65536.1 - 0.55 10.5 4.5 1.9 8.8 4.5 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain OMPdecase PF00215.24 EJP65537.1 - 5e-105 350.1 0.0 5.9e-105 349.8 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Zn_clus PF00172.18 EJP65538.1 - 4.4e-07 29.9 8.3 7.2e-07 29.2 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP65538.1 - 5.2e-06 25.7 0.0 8.5e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-CCCH PF00642.24 EJP65539.1 - 0.0039 17.1 1.1 0.0039 17.1 1.1 3.2 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EJP65539.1 - 0.035 14.8 0.4 0.035 14.8 0.4 2.5 1 1 1 2 2 2 0 Torus domain DUF5082 PF16888.5 EJP65539.1 - 0.13 12.5 0.2 0.24 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) zf_CCCH_4 PF18345.1 EJP65539.1 - 0.85 9.8 11.1 0.19 11.9 1.2 3.8 3 0 0 3 3 3 0 Zinc finger domain S-methyl_trans PF02574.16 EJP65540.1 - 1.4e-61 208.7 0.0 1.6e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase adh_short PF00106.25 EJP65541.1 - 1.1e-42 145.7 1.9 1.3e-42 145.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP65541.1 - 1.4e-33 116.4 1.0 1.7e-33 116.1 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP65541.1 - 5.1e-15 55.8 1.4 5.1e-15 55.8 1.4 1.4 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 EJP65541.1 - 0.00055 19.9 2.4 0.00082 19.3 2.3 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EJP65541.1 - 0.032 13.7 0.9 0.056 12.9 0.4 1.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family tRNA_m1G_MT PF01746.21 EJP65541.1 - 0.04 13.6 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase MFS_1 PF07690.16 EJP65542.1 - 7.3e-20 71.2 26.3 1.4e-12 47.2 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP65542.1 - 6.8e-18 64.8 12.6 1.9e-17 63.3 12.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DnaJ_CXXCXGXG PF00684.19 EJP65543.1 - 0.013 15.9 4.3 0.013 15.9 4.3 2.3 2 1 0 2 2 2 0 DnaJ central domain LAT PF15234.6 EJP65543.1 - 4.2 7.0 6.2 0.38 10.5 0.4 1.9 1 1 1 2 2 2 0 Linker for activation of T-cells ADIP PF11559.8 EJP65544.1 - 0.0028 17.8 14.3 0.0028 17.8 14.3 3.2 3 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding PPE PF00823.19 EJP65544.1 - 0.013 15.6 4.3 0.034 14.2 4.3 1.7 1 0 0 1 1 1 0 PPE family DUF2347 PF09804.9 EJP65544.1 - 0.02 14.5 2.1 0.042 13.4 2.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Fib_alpha PF08702.10 EJP65544.1 - 0.034 14.3 14.4 0.059 13.5 8.8 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CotJB PF12652.7 EJP65544.1 - 0.17 12.2 0.7 8.3 6.7 0.0 2.6 1 1 1 2 2 2 0 CotJB protein DUF3450 PF11932.8 EJP65544.1 - 0.23 10.8 21.6 0.7 9.1 16.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CorA PF01544.18 EJP65544.1 - 0.26 10.6 5.4 0.53 9.6 5.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4200 PF13863.6 EJP65544.1 - 0.38 11.2 37.0 0.32 11.4 6.3 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EJP65544.1 - 3.4 7.7 13.3 0.047 13.7 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EJP65544.1 - 3.8 7.5 15.5 0.16 12.0 6.4 2.9 2 1 1 3 3 3 0 Laminin Domain II PilJ PF13675.6 EJP65544.1 - 4.5 7.3 15.6 1.7 8.7 2.8 3.5 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term MAD PF05557.13 EJP65544.1 - 9.5 4.4 33.0 0.83 7.9 26.9 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein Ribosomal_L7Ae PF01248.26 EJP65545.1 - 9.4e-25 86.2 0.0 1.1e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 EJP65546.1 - 5.8e-45 152.5 0.0 7.1e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Vps62 PF06101.11 EJP65549.1 - 2.5e-08 32.7 0.4 4.4e-08 31.9 0.4 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DUF1302 PF06980.11 EJP65549.1 - 0.039 12.6 0.1 0.063 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) TFIIIC_sub6 PF10419.9 EJP65550.1 - 7.3e-26 89.9 0.0 1.3e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain His_biosynth PF00977.21 EJP65551.1 - 3.3e-46 157.6 0.1 1.2e-45 155.7 0.1 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EJP65551.1 - 1.5e-19 70.5 0.0 2.5e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EJP65551.1 - 3.9e-08 33.4 0.0 2.4e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EJP65551.1 - 3.8e-06 26.6 0.0 8.7e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 EJP65551.1 - 0.033 13.3 0.0 0.091 11.8 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 EJP65551.1 - 0.045 13.5 0.1 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 Pantoate_transf PF02548.15 EJP65551.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase ODC_AZ PF02100.17 EJP65552.1 - 1e-43 147.9 0.1 1.4e-43 147.4 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ArfGap PF01412.18 EJP65553.1 - 1.6e-37 128.1 1.0 1.6e-37 128.1 1.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 EJP65553.1 - 0.27 11.2 1.5 0.62 10.0 0.0 2.3 2 1 0 2 2 2 0 UBA/TS-N domain Cg6151-P PF10233.9 EJP65554.1 - 8.5e-41 138.8 14.3 1e-40 138.6 14.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PRA1 PF03208.19 EJP65554.1 - 0.012 15.2 10.9 0.016 14.8 10.9 1.2 1 0 0 1 1 1 0 PRA1 family protein DapB_N PF01113.20 EJP65555.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EJP65555.1 - 0.12 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CENP-L PF13092.6 EJP65556.1 - 8.4e-53 178.9 0.0 7.4e-51 172.6 0.0 2.1 2 0 0 2 2 2 2 Kinetochore complex Sim4 subunit Fta1 KaiB PF07689.12 EJP65556.1 - 0.067 12.9 0.0 7.3 6.4 0.0 2.5 2 0 0 2 2 2 0 KaiB domain NAD_binding_7 PF13241.6 EJP65557.1 - 1.3e-29 102.6 0.1 2.6e-29 101.7 0.1 1.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EJP65557.1 - 7.2e-28 96.0 0.2 1.2e-27 95.3 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EJP65557.1 - 1.4e-13 50.0 0.3 2.3e-13 49.3 0.3 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 EJP65557.1 - 0.00038 19.8 0.1 0.00054 19.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Cytotoxic PF09000.10 EJP65557.1 - 0.16 12.3 0.0 0.46 10.9 0.0 1.8 2 0 0 2 2 2 0 Cytotoxic FYVE PF01363.21 EJP65558.1 - 7.4e-24 83.7 19.7 5.9e-17 61.6 4.4 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EJP65558.1 - 9.2e-17 60.5 3.8 1.9e-16 59.5 3.8 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 EJP65558.1 - 0.00015 21.8 2.0 0.00015 21.8 2.0 3.8 3 1 1 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 EJP65558.1 - 0.013 15.8 11.3 0.026 14.8 0.1 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 EJP65558.1 - 0.039 14.0 8.5 0.14 12.2 0.4 3.7 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 EJP65558.1 - 0.064 13.6 3.7 0.48 10.8 0.0 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) bZIP_1 PF00170.21 EJP65558.1 - 0.25 11.4 0.1 0.25 11.4 0.1 3.4 3 0 0 3 3 3 0 bZIP transcription factor zinc_ribbon_9 PF14369.6 EJP65558.1 - 0.26 11.6 3.9 1.8 8.9 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon ABC_tran_CTD PF16326.5 EJP65558.1 - 0.5 10.7 5.5 12 6.2 3.8 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain Rad50_zn_hook PF04423.14 EJP65558.1 - 0.5 10.2 2.7 7.3 6.5 0.1 3.4 3 0 0 3 3 2 0 Rad50 zinc hook motif C6_DPF PF10170.9 EJP65558.1 - 0.55 10.6 3.6 0.29 11.5 0.4 2.2 2 0 0 2 2 2 0 Cysteine-rich domain zf-C2H2_4 PF13894.6 EJP65558.1 - 1.6 9.8 0.0 1.6 9.8 0.0 5.7 5 1 1 6 6 5 0 C2H2-type zinc finger IBR PF01485.21 EJP65558.1 - 2.2 8.6 15.9 0.091 13.0 1.1 3.6 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain DUF5446 PF17522.2 EJP65558.1 - 3.4 7.9 5.1 0.95 9.7 0.7 2.3 3 0 0 3 3 2 0 Family of unknown function (DUF5446) zf-TFIIB PF13453.6 EJP65558.1 - 6.9 6.1 7.0 28 4.2 0.7 3.7 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-CRD PF17979.1 EJP65558.1 - 7 6.7 15.6 3.3 7.8 1.2 3.5 2 1 1 3 3 3 0 Cysteine rich domain with multizinc binding regions Ank_4 PF13637.6 EJP65559.1 - 2.5e-17 63.0 0.3 5.5e-10 39.6 0.1 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP65559.1 - 1.2e-10 40.6 0.1 0.00042 20.5 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EJP65559.1 - 1.3e-10 41.2 2.3 9.7e-05 22.6 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EJP65559.1 - 2e-10 41.1 0.1 0.0013 19.2 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP65559.1 - 4.4e-06 26.9 0.1 0.19 12.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EJP65559.1 - 0.00047 20.0 0.4 0.004 17.0 0.1 2.4 2 1 0 2 2 2 1 KilA-N domain Lipoprotein_20 PF13942.6 EJP65559.1 - 0.04 13.8 1.5 0.082 12.8 1.5 1.5 1 0 0 1 1 1 0 YfhG lipoprotein Filament PF00038.21 EJP65559.1 - 0.85 9.1 7.1 1.7 8.1 7.1 1.4 1 0 0 1 1 1 0 Intermediate filament protein YmgB PF10798.8 EJP65559.1 - 0.93 9.4 2.5 12 5.8 0.1 3.5 4 0 0 4 4 4 0 Biofilm development protein YmgB/AriR Muted PF14942.6 EJP65559.1 - 1.1 9.6 6.9 2.2 8.6 6.1 1.9 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Complex1_LYR PF05347.15 EJP65560.1 - 6.6e-06 26.1 1.7 2.1e-05 24.5 0.7 2.4 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EJP65560.1 - 0.042 14.6 0.2 0.098 13.4 0.2 1.6 1 0 0 1 1 1 0 Complex1_LYR-like Acetyltransf_1 PF00583.25 EJP65561.1 - 4.6e-16 59.1 0.0 7.1e-16 58.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP65561.1 - 3e-08 34.0 0.0 4.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP65561.1 - 3.6e-07 30.2 0.0 5.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP65561.1 - 3.8e-07 30.0 0.0 6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EJP65561.1 - 0.00054 20.7 0.0 0.00072 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EJP65561.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Choline_kinase PF01633.20 EJP65562.1 - 2.6e-19 69.7 0.0 7.3e-19 68.2 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EJP65562.1 - 1.5e-06 28.4 0.1 4.5e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Amidoligase_2 PF12224.8 EJP65563.1 - 7.9e-06 25.7 0.0 0.014 15.1 0.0 2.9 2 1 0 2 2 2 2 Putative amidoligase enzyme MFS_1 PF07690.16 EJP65564.1 - 4.4e-35 121.2 20.6 6.6e-35 120.7 20.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 EJP65564.1 - 0.16 11.6 0.2 0.16 11.6 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) AA_permease_2 PF13520.6 EJP65566.1 - 3.8e-89 299.4 24.2 4.8e-89 299.1 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP65566.1 - 6.2e-18 64.6 21.6 8.5e-18 64.2 21.6 1.1 1 0 0 1 1 1 1 Amino acid permease AltA1 PF16541.5 EJP65567.1 - 4.3e-30 104.8 3.3 4.3e-30 104.8 3.3 1.5 2 0 0 2 2 2 1 Alternaria alternata allergen 1 Glyco_hydro_2_C PF02836.17 EJP65568.1 - 7e-13 48.4 0.0 2.4e-11 43.3 0.0 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EJP65568.1 - 1.6e-11 44.4 0.1 2.7e-09 37.2 0.1 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EJP65568.1 - 7.1e-07 29.9 0.5 2e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 GBR_NSP5 PF17580.2 EJP65568.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 AAA_22 PF13401.6 EJP65569.1 - 0.0081 16.4 0.1 0.7 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP65569.1 - 0.034 14.5 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EJP65569.1 - 0.039 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EJP65569.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin p450 PF00067.22 EJP65570.1 - 1.4e-61 208.7 0.0 2e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SRP19 PF01922.17 EJP65572.1 - 9.7e-34 116.2 0.1 1.8e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 SRP19 protein Dynactin PF12455.8 EJP65573.1 - 3.6e-106 354.6 10.8 3.6e-106 354.6 10.8 3.6 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 EJP65573.1 - 3.7e-22 78.1 0.2 6.2e-22 77.4 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 EJP65573.1 - 0.00028 20.3 18.9 0.00028 20.3 18.9 4.8 3 2 2 5 5 5 1 Uncharacterized coiled-coil protein (DUF2353) DHR10 PF18595.1 EJP65573.1 - 0.0046 17.0 8.1 0.0046 17.0 8.1 7.9 3 2 6 9 9 9 1 Designed helical repeat protein 10 domain HMG_box PF00505.19 EJP65574.1 - 8.8e-22 77.3 3.2 1.7e-21 76.4 3.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EJP65574.1 - 2.4e-06 28.1 1.2 2.4e-06 28.1 1.2 1.8 2 0 0 2 2 2 1 HMG-box domain TIP49 PF06068.13 EJP65575.1 - 5.6e-168 558.6 0.1 6.9e-168 558.3 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EJP65575.1 - 2.2e-25 88.5 0.2 5.7e-25 87.2 0.2 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EJP65575.1 - 1.3e-10 41.8 0.3 4.3e-07 30.4 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EJP65575.1 - 6.2e-10 39.0 0.9 2.9e-07 30.4 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EJP65575.1 - 0.00029 21.1 0.2 0.41 10.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJP65575.1 - 0.00057 20.3 0.1 0.0056 17.1 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EJP65575.1 - 0.00077 19.7 0.5 0.0022 18.3 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EJP65575.1 - 0.0024 17.9 0.2 0.14 12.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EJP65575.1 - 0.0047 17.3 5.1 0.12 12.7 0.3 2.8 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EJP65575.1 - 0.0059 17.2 0.0 0.018 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EJP65575.1 - 0.011 15.3 0.1 0.067 12.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EJP65575.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EJP65575.1 - 0.02 14.3 0.2 0.58 9.5 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EJP65575.1 - 0.02 14.2 0.2 0.062 12.6 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 EJP65575.1 - 0.022 14.5 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EJP65575.1 - 0.024 14.4 0.1 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 EJP65575.1 - 0.048 12.9 0.1 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EJP65575.1 - 0.088 12.5 0.5 2.8 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJP65575.1 - 0.092 12.2 0.1 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region EamA PF00892.20 EJP65576.1 - 2.6e-20 73.0 32.8 1.5e-10 41.4 7.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Actino_peptide PF14408.6 EJP65576.1 - 0.071 13.2 0.7 0.15 12.1 0.7 1.5 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes RNA_pol_RpbG PF16992.5 EJP65576.1 - 0.17 11.9 0.7 1.2 9.2 0.5 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G Trp_oprn_chp PF09534.10 EJP65576.1 - 2.3 8.0 8.7 1 9.1 3.9 2.3 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TFIID-18kDa PF02269.16 EJP65577.1 - 2.1e-19 69.3 0.1 3.6e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 EJP65577.1 - 0.0019 18.6 1.4 0.0081 16.5 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EJP65577.1 - 0.0069 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EJP65577.1 - 0.011 16.0 1.3 0.06 13.6 0.0 2.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EJP65577.1 - 0.013 15.7 0.1 0.019 15.0 0.1 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold FYDLN_acid PF09538.10 EJP65577.1 - 0.069 13.8 4.9 0.12 13.1 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1242 PF06842.12 EJP65578.1 - 1.4e-17 63.1 0.7 2.2e-17 62.5 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) 2-Hacid_dh_C PF02826.19 EJP65579.1 - 4.6e-46 156.4 0.1 2.4e-45 154.1 0.1 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJP65579.1 - 4.1e-10 39.4 0.0 2e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EJP65579.1 - 0.0031 17.7 0.1 0.0068 16.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EJP65579.1 - 0.043 14.4 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EJP65579.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 EJP65580.1 - 1.1e-53 182.8 24.2 6.9e-52 176.8 24.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP65580.1 - 7.1e-17 61.4 33.7 1.9e-08 33.6 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PEP_hydrolase PF09370.10 EJP65581.1 - 5.3e-135 448.8 0.3 6e-135 448.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 EJP65581.1 - 8.5e-06 25.4 0.2 1.5e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase UPF0261 PF06792.11 EJP65582.1 - 8.3e-161 535.5 0.3 9.3e-161 535.3 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PrpR_N PF06506.11 EJP65582.1 - 0.022 14.4 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Propionate catabolism activator Tcp11 PF05794.13 EJP65583.1 - 6.2e-111 371.6 2.5 1.3e-110 370.5 2.5 1.5 1 1 0 1 1 1 1 T-complex protein 11 Peptidase_M75 PF09375.10 EJP65583.1 - 0.014 14.9 0.5 0.037 13.5 0.1 1.8 2 0 0 2 2 2 0 Imelysin RsbRD_N PF14361.6 EJP65583.1 - 0.075 13.7 0.0 4.1 8.1 0.0 2.6 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain SOG2 PF10428.9 EJP65583.1 - 0.22 10.7 12.4 0.12 11.5 1.7 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein Uds1 PF15456.6 EJP65584.1 - 4.7e-34 117.3 3.2 4.7e-34 117.3 3.2 6.3 3 1 3 6 6 6 1 Up-regulated During Septation CENP-H PF05837.12 EJP65584.1 - 0.0054 17.1 10.5 0.0054 17.1 10.5 6.9 5 1 2 7 7 7 2 Centromere protein H (CENP-H) HMG_box PF00505.19 EJP65584.1 - 0.28 11.6 6.1 0.18 12.3 1.4 3.0 2 0 0 2 2 2 0 HMG (high mobility group) box DUF503 PF04456.12 EJP65584.1 - 0.35 10.8 3.1 0.67 9.8 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF503) Rhomboid PF01694.22 EJP65585.1 - 1.7e-07 31.4 3.9 3.3e-07 30.4 3.9 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EJP65585.1 - 8.8e-07 29.4 0.1 1.8e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.15 EJP65585.1 - 0.00016 21.7 2.8 0.00026 21.0 2.8 1.3 1 0 0 1 1 1 1 Der1-like family PP2C PF00481.21 EJP65586.1 - 2.9e-44 151.6 0.0 4.9e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EJP65586.1 - 0.0001 22.1 0.1 0.0002 21.0 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EJP65586.1 - 0.0011 18.9 0.1 0.28 11.1 0.0 3.0 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) DUF5572 PF17733.1 EJP65587.1 - 1.1e-16 60.3 0.5 2.1e-16 59.5 0.5 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DUF4880 PF16220.5 EJP65587.1 - 0.0022 17.9 0.5 0.0084 16.0 0.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) PUF PF00806.19 EJP65588.1 - 1.1e-39 131.9 0.2 2.5e-06 26.9 0.0 9.0 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat MRP-S33 PF08293.11 EJP65588.1 - 5.8e-28 97.0 0.3 1.6e-27 95.5 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit S27 Phage_lambda_P PF06992.11 EJP65588.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Replication protein P ATP-synt_D PF01813.17 EJP65588.1 - 0.086 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 ATP synthase subunit D Ribonuclease_3 PF00636.26 EJP65589.1 - 1.9e-15 57.3 0.0 4.6e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EJP65589.1 - 6.1e-09 36.1 0.0 1.8e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 EJP65589.1 - 0.066 13.9 0.1 0.25 12.1 0.0 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif CorA PF01544.18 EJP65589.1 - 0.21 10.9 0.6 0.35 10.1 0.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ACBP PF00887.19 EJP65590.1 - 1.7e-23 82.6 0.0 4.2e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein Molybdopterin PF00384.22 EJP65591.1 - 4.6e-72 243.3 0.0 4.3e-70 236.8 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 EJP65591.1 - 1.2e-18 67.5 0.0 3.8e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2_4 PF13510.6 EJP65591.1 - 6.1e-16 58.2 0.3 4.4e-15 55.5 0.4 2.5 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 EJP65591.1 - 6.3e-16 57.6 0.2 6.3e-16 57.6 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EJP65591.1 - 0.0005 20.0 0.3 0.0005 20.0 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EJP65591.1 - 0.037 13.8 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 EJP65591.1 - 0.12 12.3 1.1 3.4 7.6 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain UPF0061 PF02696.14 EJP65592.1 - 8.6e-127 423.7 0.0 1.1e-126 423.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family XRCC4 PF06632.12 EJP65593.1 - 1.1e-07 31.0 18.1 1.2e-06 27.6 18.1 2.2 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Bul1_C PF04426.12 EJP65593.1 - 0.0018 17.7 2.7 0.0029 17.0 2.7 1.2 1 0 0 1 1 1 1 Bul1 C terminus DUF507 PF04368.13 EJP65593.1 - 0.039 13.9 2.3 0.066 13.1 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF507) DUF3585 PF12130.8 EJP65593.1 - 0.05 13.8 4.7 0.097 12.8 4.7 1.4 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain Cupredoxin_1 PF13473.6 EJP65593.1 - 0.23 11.6 2.0 4.3 7.5 0.4 2.3 2 0 0 2 2 2 0 Cupredoxin-like domain YojJ PF10372.9 EJP65593.1 - 3.4 7.8 4.8 36 4.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Aldo_ket_red PF00248.21 EJP65594.1 - 7e-35 120.6 0.0 8.4e-28 97.4 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Zn_clus PF00172.18 EJP65595.1 - 4.6e-07 29.9 11.3 1.2e-06 28.5 11.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Blt1 PF12754.7 EJP65597.1 - 7.8e-38 130.1 0.0 1.1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 EJP65597.1 - 2.7e-17 62.1 2.3 4.4e-17 61.4 2.3 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 EJP65597.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin family Cpn60_TCP1 PF00118.24 EJP65598.1 - 1.3e-84 284.7 10.4 2.7e-84 283.6 10.4 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family GvpK PF05121.12 EJP65599.1 - 0.0072 16.3 2.0 0.013 15.6 2.0 1.4 1 0 0 1 1 1 1 Gas vesicle protein K HALZ PF02183.18 EJP65599.1 - 0.023 14.9 0.3 0.044 14.0 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 EJP65599.1 - 0.068 13.0 1.8 0.46 10.3 1.8 2.1 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 EJP65599.1 - 0.13 12.7 0.2 25 5.4 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 EJP65599.1 - 0.14 12.4 3.4 0.93 9.7 1.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 EJP65599.1 - 0.78 10.2 4.2 0.9 10.0 2.6 2.0 1 1 0 1 1 1 0 Cell division protein ZapB FCP1_C PF09309.10 EJP65600.1 - 0.0096 15.8 7.5 0.011 15.6 7.5 1.1 1 0 0 1 1 1 1 FCP1, C-terminal SURF2 PF05477.11 EJP65600.1 - 0.045 13.4 4.9 0.092 12.4 4.9 1.5 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) GcrA PF07750.11 EJP65600.1 - 0.19 12.2 3.3 0.49 10.8 3.3 1.7 1 1 0 1 1 1 0 GcrA cell cycle regulator Sporozoite_P67 PF05642.11 EJP65601.1 - 2.7 6.0 9.4 3.5 5.6 9.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.14 EJP65602.1 - 0.54 10.0 3.7 0.76 9.5 3.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ORC6 PF05460.13 EJP65602.1 - 0.77 9.0 2.7 0.91 8.7 2.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Peptidase_S10 PF00450.22 EJP65606.1 - 1.3e-63 215.9 2.0 4.7e-63 214.0 2.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 EJP65606.1 - 0.0051 16.3 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family UFD1 PF03152.14 EJP65608.1 - 1.3e-67 226.6 0.0 1.7e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Cellulase PF00150.18 EJP65609.1 - 1e-23 84.2 0.7 2e-23 83.3 0.7 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EJP65609.1 - 1.2e-18 67.4 0.0 2.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_42 PF02449.15 EJP65609.1 - 1.5e-06 27.8 0.5 5.9e-06 25.9 0.0 2.2 3 0 0 3 3 3 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 EJP65609.1 - 0.00069 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 GYF PF02213.16 EJP65610.1 - 3e-10 39.6 2.0 8.5e-10 38.1 2.0 1.8 1 0 0 1 1 1 1 GYF domain Gp_dh_C PF02800.20 EJP65611.1 - 4.6e-72 240.8 0.0 6.4e-72 240.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EJP65611.1 - 3.3e-38 130.1 0.1 6.8e-38 129.1 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EJP65611.1 - 0.025 14.7 0.3 0.086 13.0 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EJP65611.1 - 0.061 12.7 0.1 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CCDC144C PF14915.6 EJP65613.1 - 0.0043 16.2 14.5 0.0043 16.2 14.5 2.8 2 1 1 3 3 3 1 CCDC144C protein coiled-coil region DUF4407 PF14362.6 EJP65613.1 - 0.65 9.3 26.8 0.046 13.1 7.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Metal_resist PF13801.6 EJP65613.1 - 1.3 9.2 8.7 2.6 8.2 0.1 2.8 2 0 0 2 2 2 0 Heavy-metal resistance Tup_N PF08581.10 EJP65613.1 - 2.7 8.4 15.7 0.59 10.5 1.2 3.8 3 1 0 3 3 3 0 Tup N-terminal Spc7 PF08317.11 EJP65613.1 - 3 6.7 37.4 0.1 11.5 11.7 3.5 3 1 1 4 4 4 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 EJP65613.1 - 3 8.2 30.1 0.2 12.0 9.6 3.5 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0242 PF06785.11 EJP65613.1 - 3.1 7.9 33.3 10 6.2 0.0 4.2 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 EJP65613.1 - 3.5 8.2 14.0 1.1 9.8 0.4 4.7 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein KIP1 PF07765.12 EJP65613.1 - 5.8 7.1 8.6 83 3.4 0.3 4.5 5 0 0 5 5 5 0 KIP1-like protein TIP49 PF06068.13 EJP65615.1 - 9.9e-154 511.7 2.0 1.4e-153 511.3 2.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EJP65615.1 - 4.6e-20 71.5 0.8 1.4e-19 70.0 0.5 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 EJP65615.1 - 8.4e-09 35.4 0.8 0.00012 21.9 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EJP65615.1 - 1.7e-08 34.9 1.0 3.3e-05 24.3 0.0 3.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EJP65615.1 - 1.1e-06 28.2 1.1 2.1e-06 27.3 1.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EJP65615.1 - 6.1e-06 26.7 0.6 1.8e-05 25.2 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EJP65615.1 - 0.00056 19.4 0.7 0.024 14.0 0.3 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EJP65615.1 - 0.0033 17.4 0.2 2.5 8.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EJP65615.1 - 0.0051 17.1 0.0 0.57 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EJP65615.1 - 0.011 15.5 0.0 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 EJP65615.1 - 0.022 15.1 2.8 1.2 9.5 2.8 2.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EJP65615.1 - 0.024 14.9 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EJP65615.1 - 0.031 13.9 0.1 0.06 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EJP65615.1 - 0.039 13.7 1.3 0.36 10.6 1.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EJP65615.1 - 0.1 12.8 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJP65615.1 - 0.13 11.8 0.2 0.56 9.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EJP65615.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HLH PF00010.26 EJP65616.1 - 1.5e-07 31.3 0.0 3.5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GET2 PF08690.10 EJP65618.1 - 2.1e-40 139.3 0.0 6.3e-40 137.8 0.0 1.7 1 1 0 1 1 1 1 GET complex subunit GET2 Sec16_C PF12931.7 EJP65619.1 - 1.1e-12 48.2 0.2 1.9e-11 44.2 0.2 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 EJP65619.1 - 5e-10 39.3 0.0 5e-10 39.3 0.0 3.4 3 1 0 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 EJP65619.1 - 2.2e-08 34.6 3.6 0.025 15.4 0.0 5.9 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP65619.1 - 0.00014 22.1 0.2 0.31 11.3 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EJP65619.1 - 0.03 13.2 0.5 1.5 7.7 0.0 2.5 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain ASXH PF13919.6 EJP65619.1 - 0.061 13.3 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Asx homology domain LRR_10 PF18805.1 EJP65619.1 - 0.094 12.4 0.1 0.32 10.7 0.1 1.9 1 0 0 1 1 1 0 Leucine-rich repeat Tox-MPTase2 PF15638.6 EJP65619.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 RRM_1 PF00076.22 EJP65620.1 - 1.2e-16 60.2 0.0 1.6e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP65620.1 - 3.8e-05 23.7 0.0 5.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EJP65620.1 - 0.0031 17.1 0.0 0.0047 16.5 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EJP65620.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 EJP65620.1 - 0.041 13.5 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Nup35_RRM PF05172.13 EJP65620.1 - 0.041 13.8 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EJP65620.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EJP65620.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 B12D PF06522.11 EJP65621.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.17 EJP65622.1 - 5.9e-15 55.3 2.4 7.3e-15 55.0 2.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EJP65622.1 - 0.00061 19.7 0.7 0.00094 19.1 0.7 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 EJP65622.1 - 0.2 11.6 1.8 0.27 11.2 1.3 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain Sde2_N_Ubi PF13019.6 EJP65623.1 - 1.1e-67 227.0 0.1 1.5e-67 226.5 0.1 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain LacI PF00356.21 EJP65623.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family S10_plectin PF03501.15 EJP65624.1 - 6.6e-42 141.5 0.1 8e-42 141.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain HECT PF00632.25 EJP65625.1 - 5.2e-75 252.8 0.0 7.1e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) L51_S25_CI-B8 PF05047.16 EJP65626.1 - 4.2e-16 58.6 0.1 6.4e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.23 EJP65627.1 - 0.00017 21.7 0.0 0.46 10.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase CSTF2_hinge PF14327.6 EJP65627.1 - 0.022 15.2 0.1 0.044 14.2 0.1 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 PPI_Ypi1 PF07491.11 EJP65628.1 - 2.6e-24 84.8 8.3 1.2e-23 82.7 8.3 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor Gag_p12 PF01141.18 EJP65628.1 - 0.059 13.7 1.4 0.059 13.7 1.4 2.4 3 0 0 3 3 3 0 Gag polyprotein, inner coat protein p12 CDC45 PF02724.14 EJP65628.1 - 1.2 7.4 7.1 1.2 7.3 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.14 EJP65628.1 - 1.2 8.5 8.7 1.8 7.9 8.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RAP1 PF07218.11 EJP65628.1 - 1.6 6.9 3.3 1.6 6.9 3.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glu-tRNAGln PF02686.15 EJP65629.1 - 1.3e-12 47.8 0.2 4.1e-12 46.2 0.2 1.7 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 EJP65630.1 - 1.4e-106 356.1 21.6 6.7e-91 304.6 16.2 2.0 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EJP65630.1 - 4e-07 30.2 10.1 0.038 14.3 0.1 4.0 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EJP65630.1 - 0.004 17.1 9.9 2 8.7 0.6 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJP65630.1 - 0.054 13.7 11.9 1.1 9.6 0.2 4.6 4 2 0 4 4 4 0 Tetratricopeptide repeat Dabb PF07876.12 EJP65630.1 - 0.067 13.8 0.2 0.29 11.8 0.1 2.1 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain TPR_14 PF13428.6 EJP65630.1 - 0.072 14.0 7.0 1.6 9.8 0.6 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EJP65630.1 - 0.72 9.8 5.7 8.4 6.4 0.9 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EJP65630.1 - 2.2 8.2 9.5 1.1 9.2 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EJP65630.1 - 4.2 7.7 16.6 1.1 9.6 0.1 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 EJP65630.1 - 5.7 8.2 19.2 1.9 9.6 0.5 5.4 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat Arm PF00514.23 EJP65631.1 - 1.4e-08 34.5 10.9 0.033 14.3 0.0 6.4 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EJP65631.1 - 0.00013 22.4 6.2 0.74 10.4 0.0 5.7 6 0 0 6 6 6 2 HEAT-like repeat DUF747 PF05346.11 EJP65631.1 - 0.044 13.3 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic membrane protein family PUL PF08324.11 EJP65631.1 - 0.17 11.1 1.7 5.8 6.1 0.2 2.7 2 0 0 2 2 2 0 PUL domain V-ATPase_H_C PF11698.8 EJP65631.1 - 2.7 8.1 3.7 11 6.2 0.2 3.3 3 2 1 4 4 4 0 V-ATPase subunit H HEAT PF02985.22 EJP65631.1 - 10 6.7 17.8 11 6.6 0.4 6.6 7 0 0 7 7 7 0 HEAT repeat Velvet PF11754.8 EJP65632.1 - 1.3e-50 172.6 0.0 1.8e-32 113.3 0.0 3.5 2 2 1 3 3 3 2 Velvet factor Macro_2 PF14519.6 EJP65633.1 - 4.5e-05 22.9 0.0 0.00012 21.6 0.0 1.6 1 1 0 1 1 1 1 Macro-like domain Ank_5 PF13857.6 EJP65635.1 - 7.2e-14 51.7 0.1 4.3e-10 39.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EJP65635.1 - 5.5e-12 45.6 0.4 3.6e-05 24.0 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EJP65635.1 - 5.8e-11 42.8 0.0 1.4e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 EJP65635.1 - 9.6e-10 38.4 1.0 2.8e-09 36.9 0.2 2.3 3 0 0 3 3 3 1 IPT/TIG domain Ank_4 PF13637.6 EJP65635.1 - 3.3e-09 37.1 0.2 9e-09 35.7 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP65635.1 - 7.9e-07 28.9 0.1 0.05 14.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat DUF1970 PF09301.10 EJP65635.1 - 1.2 9.4 4.3 2.6 8.4 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) Med13_C PF06333.12 EJP65636.1 - 1.2e-80 271.2 0.2 4e-80 269.6 0.2 1.9 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EJP65636.1 - 4.2e-22 78.9 3.9 7.7e-22 78.1 3.9 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 EJP65636.1 - 1.4e-12 47.9 1.3 6.9e-05 22.8 0.5 3.0 2 1 1 3 3 3 2 MID domain of medPIWI DUF4646 PF15496.6 EJP65636.1 - 0.07 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) AbiEi_3_N PF17194.4 EJP65636.1 - 0.083 12.9 0.7 0.19 11.8 0.7 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain NUC153 PF08159.12 EJP65637.1 - 2.5e-11 43.2 0.3 4.5e-11 42.4 0.3 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EJP65637.1 - 3.9e-06 27.5 0.3 0.67 10.9 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP65637.1 - 0.026 14.8 0.0 0.084 13.2 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3568 PF12092.8 EJP65637.1 - 0.093 12.8 0.1 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) ECSCR PF15820.5 EJP65638.1 - 1.2e-05 25.1 0.6 2.3e-05 24.1 0.6 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator LapA_dom PF06305.11 EJP65638.1 - 0.0077 16.0 1.2 0.012 15.4 1.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Zn_peptidase PF04228.13 EJP65638.1 - 0.086 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Shisa PF13908.6 EJP65638.1 - 0.11 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Amnionless PF14828.6 EJP65638.1 - 0.15 10.8 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless HemY_N PF07219.13 EJP65638.1 - 0.24 11.6 3.2 0.31 11.3 2.2 1.6 1 1 1 2 2 2 0 HemY protein N-terminus TMF_TATA_bd PF12325.8 EJP65639.1 - 0.028 14.7 0.3 0.028 14.7 0.3 5.6 3 2 2 6 6 6 0 TATA element modulatory factor 1 TATA binding Uso1_p115_C PF04871.13 EJP65639.1 - 0.046 14.1 0.1 0.046 14.1 0.1 4.8 5 1 0 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region Occludin_ELL PF07303.13 EJP65639.1 - 0.87 10.4 0.0 0.87 10.4 0.0 5.9 4 1 2 6 6 6 0 Occludin homology domain Ribosomal_L33 PF00471.20 EJP65640.1 - 8.4e-06 26.1 0.0 1e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 DUF2470 PF10615.9 EJP65641.1 - 2.4e-22 79.4 0.4 3.3e-22 78.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Helicase_C PF00271.31 EJP65642.1 - 5.9e-18 65.2 0.0 1e-15 58.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP65642.1 - 6.4e-16 58.6 0.0 1.4e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EJP65642.1 - 5.8e-11 43.0 0.9 1.6e-10 41.6 0.9 1.8 1 0 0 1 1 1 1 RecQ zinc-binding TRADD_N PF09034.10 EJP65642.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain SOG2 PF10428.9 EJP65643.1 - 6.2e-72 243.4 3.0 7.9e-57 193.6 1.7 3.7 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 EJP65643.1 - 3e-14 52.5 3.4 2.2e-06 27.3 0.1 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EJP65643.1 - 1.2e-13 50.9 6.1 8.5e-06 26.0 0.3 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) DUF2408 PF10303.9 EJP65643.1 - 8.2e-05 23.2 0.0 0.00028 21.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) LRR_6 PF13516.6 EJP65643.1 - 0.019 15.0 5.3 4.4 7.6 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EJP65643.1 - 0.11 13.1 12.4 7.5 7.5 0.2 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat ZYG-11_interact PF05884.12 EJP65643.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 GCN5L1 PF06320.13 EJP65644.1 - 7.3e-14 51.9 1.5 1.3e-13 51.1 1.5 1.5 1 1 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Serglycin PF04360.12 EJP65644.1 - 0.45 10.4 3.8 0.38 10.7 1.4 2.0 2 0 0 2 2 2 0 Serglycin SOG2 PF10428.9 EJP65644.1 - 4.4 6.4 12.6 5.9 6.0 12.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Steroid_dh PF02544.16 EJP65645.1 - 4.1e-29 101.5 0.2 6.4e-29 100.9 0.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EJP65645.1 - 0.0003 20.4 0.5 0.00043 19.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ribosomal_S8e PF01201.22 EJP65647.1 - 1.3e-54 184.1 1.4 1.6e-54 183.8 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e RabGAP-TBC PF00566.18 EJP65648.1 - 4.6e-51 173.5 0.4 3.3e-49 167.5 0.0 2.5 1 1 1 2 2 2 1 Rab-GTPase-TBC domain KASH_CCD PF14662.6 EJP65648.1 - 0.0029 17.4 25.3 0.014 15.3 25.3 2.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 EJP65648.1 - 0.078 13.2 22.5 0.12 12.6 0.4 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper TolA_bind_tri PF16331.5 EJP65648.1 - 0.67 10.1 9.6 0.29 11.3 2.4 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation UPF0242 PF06785.11 EJP65648.1 - 9.2 6.3 34.4 17 5.4 26.0 4.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF913 PF06025.12 EJP65649.1 - 7.5e-128 426.6 0.0 7.5e-128 426.6 0.0 6.6 7 2 0 7 7 7 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EJP65649.1 - 2.9e-120 402.0 11.2 1.6e-119 399.6 11.2 2.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EJP65649.1 - 8.6e-93 311.2 0.1 2.5e-92 309.7 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EJP65649.1 - 3.1e-25 86.8 19.2 3e-08 32.8 0.4 4.0 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 EJP65649.1 - 0.0061 16.4 0.1 0.017 15.0 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain MAS20 PF02064.15 EJP65649.1 - 8.1 6.6 8.3 35 4.5 8.3 2.1 1 0 0 1 1 1 0 MAS20 protein import receptor Ribosomal_S6e PF01092.19 EJP65650.1 - 1.2e-56 190.0 0.0 2.3e-56 189.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Ctf8 PF09696.10 EJP65651.1 - 1.6e-39 135.5 0.5 1.7e-38 132.1 0.5 2.0 1 1 0 1 1 1 1 Ctf8 APH PF01636.23 EJP65652.1 - 2.9e-19 70.0 3.7 3.7e-19 69.6 3.7 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EJP65652.1 - 7.4e-06 25.4 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 2 Fructosamine kinase DprA_WH PF17782.1 EJP65652.1 - 0.13 12.4 3.5 3.4 7.9 0.5 2.9 2 0 0 2 2 2 0 DprA winged helix domain Diphthamide_syn PF01866.17 EJP65653.1 - 8.4e-115 383.4 0.0 1.1e-114 383.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Aldose_epim PF01263.20 EJP65654.1 - 4.9e-45 154.1 0.4 6.2e-45 153.8 0.4 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ATP-synt_ab PF00006.25 EJP65655.1 - 1.9e-65 220.5 0.0 2.7e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EJP65655.1 - 4.9e-14 52.6 0.6 1e-13 51.6 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 EJP65655.1 - 0.0091 16.1 0.0 0.031 14.4 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5535) DUF561 PF04481.12 EJP65655.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) HMGL-like PF00682.19 EJP65656.1 - 9.8e-42 143.3 0.0 4.2e-31 108.5 0.0 2.0 2 0 0 2 2 2 2 HMGL-like Tubulin PF00091.25 EJP65657.1 - 1.2e-66 224.7 0.0 1.8e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EJP65657.1 - 2.5e-50 169.9 0.2 4.1e-50 169.2 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EJP65657.1 - 0.0055 16.4 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Pga1 PF10333.9 EJP65658.1 - 0.0023 17.8 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator WW PF00397.26 EJP65659.1 - 7.6e-12 45.1 0.2 1.6e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 WW domain Mo-co_dimer PF03404.16 EJP65660.1 - 0.091 12.8 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain LsmAD PF06741.13 EJP65661.1 - 3.3e-27 94.8 2.3 3.3e-27 94.8 2.3 2.3 2 0 0 2 2 2 1 LsmAD domain Peptidase_M16 PF00675.20 EJP65662.1 - 3.4e-18 66.1 0.0 5.5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EJP65662.1 - 3.3e-14 53.3 0.0 5.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Mtf2_C PF14061.6 EJP65662.1 - 0.081 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 RNA_pol_Rpc82 PF05645.13 EJP65663.1 - 2e-50 172.0 0.1 1.2e-47 162.8 0.1 2.8 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EJP65663.1 - 1.7e-17 63.2 1.7 5.8e-14 51.9 0.1 3.8 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EJP65663.1 - 0.00023 21.0 0.0 0.11 12.4 0.0 3.2 2 1 0 2 2 2 2 TFIIE alpha subunit Rrf2 PF02082.20 EJP65663.1 - 0.0075 16.6 0.1 1.5 9.2 0.0 2.9 2 0 0 2 2 2 1 Transcriptional regulator HTH_24 PF13412.6 EJP65663.1 - 0.058 13.0 0.2 0.51 9.9 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Mito_carr PF00153.27 EJP65664.1 - 4.3e-29 100.3 0.3 3.4e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Apolipoprotein PF01442.18 EJP65665.1 - 0.0049 16.8 2.3 0.0049 16.8 2.3 9.5 4 3 4 8 8 8 3 Apolipoprotein A1/A4/E domain Spc42p PF11544.8 EJP65665.1 - 0.022 14.8 0.9 6.5 6.8 0.1 4.7 3 0 0 3 3 3 0 Spindle pole body component Spc42p MIF4G PF02854.19 EJP65665.1 - 0.086 12.5 1.0 0.33 10.5 0.1 2.5 2 0 0 2 2 2 0 MIF4G domain AlphaC_C PF17480.2 EJP65665.1 - 0.16 12.0 3.8 2.3 8.3 0.0 3.5 3 0 0 3 3 3 0 AlphaC C-terminal ApoLp-III PF07464.11 EJP65665.1 - 0.29 11.2 50.3 0.098 12.7 2.8 8.3 4 3 4 9 9 9 0 Apolipophorin-III precursor (apoLp-III) FtsQ PF03799.15 EJP65665.1 - 0.45 11.3 3.7 1.9 9.3 0.0 4.1 4 0 0 4 4 4 0 Cell division protein FtsQ Iron_permease PF04120.12 EJP65665.1 - 0.57 10.0 4.7 0.89 9.3 1.5 3.2 2 0 0 2 2 2 0 Low affinity iron permease DUF4208 PF13907.6 EJP65665.1 - 2.2 8.8 14.4 2.1 8.9 0.1 6.2 4 2 2 6 6 6 0 Domain of unknown function (DUF4208) DUF948 PF06103.11 EJP65665.1 - 3.7 7.9 37.4 19 5.6 0.0 9.7 8 2 2 10 10 10 0 Bacterial protein of unknown function (DUF948) DASH_Dad3 PF08656.10 EJP65666.1 - 6.3e-34 115.9 0.4 7.5e-34 115.7 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.15 EJP65667.1 - 1.8e-20 72.2 1.5 3.5e-19 68.0 0.0 2.9 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EJP65667.1 - 3.5e-16 58.9 1.6 8.7e-16 57.7 1.6 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF3138 PF11336.8 EJP65667.1 - 0.43 9.1 6.2 0.97 8.0 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) EST1_DNA_bind PF10373.9 EJP65668.1 - 3.6e-13 49.6 0.0 1.2e-12 48.0 0.0 1.9 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain zf-C2H2_12 PF18658.1 EJP65668.1 - 0.075 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger C2H2-type ThiF PF00899.21 EJP65669.1 - 1.3e-39 136.0 0.0 2.6e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EJP65669.1 - 6.8e-05 23.1 0.0 0.00028 21.1 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EJP65669.1 - 0.0021 18.4 0.0 0.011 16.1 0.0 2.1 3 0 0 3 3 3 1 Putative NAD(P)-binding TrkA_N PF02254.18 EJP65669.1 - 0.0078 16.5 0.2 0.036 14.3 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EJP65669.1 - 0.013 15.1 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EJP65669.1 - 0.071 12.8 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Melibiase_2 PF16499.5 EJP65669.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A Coatomer_E PF04733.14 EJP65669.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit Atg29_N PF18388.1 EJP65671.1 - 3e-26 91.0 1.7 6.7e-26 89.9 1.7 1.7 1 0 0 1 1 1 1 Atg29 N-terminal domain Thioredox_DsbH PF03190.15 EJP65672.1 - 4.2e-58 195.9 0.0 7.3e-58 195.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EJP65672.1 - 1.3e-05 25.3 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Sec31 PF11549.8 EJP65672.1 - 0.0013 18.6 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 Protein transport protein SEC31 Sigma70_r3 PF04539.16 EJP65672.1 - 0.11 12.6 0.3 0.42 10.8 0.2 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 Histone_HNS PF00816.21 EJP65672.1 - 0.12 13.3 1.2 2.2 9.2 0.1 2.6 2 0 0 2 2 2 0 H-NS histone family DLIC PF05783.11 EJP65673.1 - 5.3e-31 108.0 0.0 2e-29 102.8 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 EJP65674.1 - 1.7e-16 59.7 0.1 4.5e-15 55.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP65674.1 - 0.0081 16.3 0.0 0.026 14.6 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif WD40 PF00400.32 EJP65675.1 - 2.2e-07 31.5 0.1 0.0081 17.0 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP65675.1 - 0.0003 21.0 0.0 0.043 14.1 0.0 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EJP65675.1 - 0.0014 16.7 0.0 0.0019 16.3 0.0 1.1 1 0 0 1 1 1 1 IKI3 family NTPase_I-T PF01931.18 EJP65675.1 - 0.022 14.6 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF84 Fungal_trans PF04082.18 EJP65676.1 - 3.8e-09 36.0 3.9 7.1e-09 35.1 3.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAPS_reduct PF01507.19 EJP65677.1 - 3.2e-29 102.2 0.0 4.8e-20 72.3 0.0 3.0 2 1 1 3 3 3 2 Phosphoadenosine phosphosulfate reductase family Septin PF00735.18 EJP65678.1 - 2.7e-108 361.5 0.1 4.8e-108 360.7 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EJP65678.1 - 0.00011 22.2 0.0 0.00029 20.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EJP65678.1 - 0.0004 20.5 2.4 0.7 9.9 0.0 3.2 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EJP65678.1 - 0.0079 16.1 0.2 0.0079 16.1 0.2 2.3 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EJP65678.1 - 0.021 14.4 0.2 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EJP65678.1 - 0.021 15.1 0.6 0.089 13.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EJP65678.1 - 0.14 12.7 3.6 11 6.4 3.7 2.3 2 0 0 2 2 2 0 AAA domain EB1 PF03271.17 EJP65678.1 - 0.35 11.1 3.7 3.5 8.0 1.3 2.7 2 0 0 2 2 2 0 EB1-like C-terminal motif Ribosomal_S17e PF00833.18 EJP65678.1 - 0.54 10.2 3.8 1.3 8.9 3.8 1.6 1 0 0 1 1 1 0 Ribosomal S17 Bax1-I PF01027.20 EJP65679.1 - 1e-51 175.7 26.1 1.2e-51 175.5 26.1 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5504 PF17608.2 EJP65679.1 - 0.72 10.0 12.1 0.23 11.6 4.3 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5504) TRAM_LAG1_CLN8 PF03798.16 EJP65680.1 - 1.8e-48 164.9 18.0 1.8e-48 164.9 18.0 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EJP65680.1 - 8e-20 70.3 0.1 8e-20 70.3 0.1 2.1 2 0 0 2 2 2 1 TRAM1-like protein AMP-binding PF00501.28 EJP65681.1 - 9.6e-84 281.4 0.0 1.3e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP65681.1 - 6.1e-18 65.6 0.1 2.9e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Beta-lactamase PF00144.24 EJP65682.1 - 2.1e-34 119.3 4.6 2.5e-34 119.0 3.1 1.8 2 1 0 2 2 2 1 Beta-lactamase Gly_transf_sug PF04488.15 EJP65683.1 - 1.2e-14 54.7 0.0 2.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cu_amine_oxid PF01179.20 EJP65684.1 - 2.8e-151 504.1 0.0 3.4e-151 503.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EJP65684.1 - 0.00029 21.0 0.1 0.00076 19.7 0.1 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 EJP65684.1 - 0.0043 17.4 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain QRPTase_C PF01729.19 EJP65685.1 - 4.2e-56 189.4 0.2 5.1e-56 189.1 0.2 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EJP65685.1 - 6.6e-18 64.6 0.6 3.4e-17 62.3 0.0 2.4 3 1 0 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain EHN PF06441.12 EJP65686.1 - 1.9e-29 102.2 0.7 3.3e-29 101.4 0.7 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EJP65686.1 - 1.6e-12 47.7 0.0 2.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP65686.1 - 0.0083 16.7 0.3 0.026 15.1 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family NADH_dhqG_C PF09326.11 EJP65686.1 - 0.063 14.0 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal TPR_2 PF07719.17 EJP65687.1 - 7.9e-12 44.3 15.5 8.9e-05 22.3 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EJP65687.1 - 2.1e-06 27.3 5.3 0.08 12.6 0.1 4.7 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 EJP65687.1 - 2e-05 24.8 15.7 0.0012 19.1 0.8 5.5 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP65687.1 - 2.1e-05 25.1 22.9 0.018 15.7 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP65687.1 - 2.2e-05 24.9 12.6 0.045 14.2 0.0 6.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP65687.1 - 2.2e-05 24.9 18.3 2.3 9.3 0.0 7.7 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EJP65687.1 - 4.3e-05 23.4 10.4 0.1 12.9 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP65687.1 - 0.00056 19.8 2.9 9.3 6.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJP65687.1 - 0.00061 19.5 14.2 0.0081 15.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EJP65687.1 - 0.025 14.6 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_10 PF13374.6 EJP65687.1 - 0.22 11.4 9.1 20 5.2 0.3 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EJP65687.1 - 0.23 11.6 5.2 4 7.6 0.0 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EJP65687.1 - 0.52 11.1 20.9 1.3 9.9 0.2 6.8 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EJP65687.1 - 0.77 10.3 3.9 1.2e+02 3.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJP65687.1 - 5.1 8.0 7.9 1.1e+02 3.7 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ATG22 PF11700.8 EJP65688.1 - 3.3e-127 425.0 22.4 3.9e-127 424.8 22.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF2157 PF09925.9 EJP65688.1 - 0.23 11.2 27.8 0.14 12.0 9.1 3.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) adh_short PF00106.25 EJP65689.1 - 1.8e-26 92.9 0.8 1.8e-26 92.9 0.8 1.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP65689.1 - 1.3e-16 60.9 1.0 1.3e-16 60.9 1.0 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EJP65689.1 - 4e-10 39.9 0.8 6.7e-10 39.1 0.8 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EJP65689.1 - 1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EJP65689.1 - 1.1e-05 25.5 5.3 2.9e-05 24.0 1.8 2.5 1 1 1 2 2 2 1 KR domain NAD_binding_4 PF07993.12 EJP65689.1 - 0.011 14.9 0.0 0.54 9.4 0.0 2.7 2 1 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 EJP65689.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 EJP65689.1 - 0.09 12.5 0.3 0.33 10.7 0.3 2.0 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FMN_bind_2 PF04299.12 EJP65690.1 - 1.3e-58 197.5 0.0 1.6e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain RTC PF01137.21 EJP65692.1 - 5e-49 166.5 0.0 1.6e-48 164.8 0.0 1.7 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase AKNA PF12443.8 EJP65692.1 - 0.17 12.5 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor PhzC-PhzF PF02567.16 EJP65693.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein IMD PF08397.11 EJP65694.1 - 8.1e-05 22.1 3.7 0.011 15.1 0.5 2.1 2 0 0 2 2 2 2 IRSp53/MIM homology domain Rab_bind PF16704.5 EJP65694.1 - 0.012 15.7 1.7 0.34 11.0 0.1 2.4 2 0 0 2 2 2 0 Rab binding domain Arfaptin PF06456.13 EJP65694.1 - 0.018 14.6 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 Arfaptin-like domain LRR_8 PF13855.6 EJP65695.1 - 3.2e-10 39.6 2.1 3.2e-10 39.6 2.1 1.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EJP65695.1 - 5.5e-08 33.0 1.3 5.5e-08 33.0 1.3 2.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EJP65695.1 - 0.015 15.7 2.1 4.1 8.3 0.7 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EJP65695.1 - 0.32 11.1 3.8 14 6.0 0.3 2.8 2 0 0 2 2 2 0 Leucine Rich repeat Pkinase PF00069.25 EJP65696.1 - 1.2e-54 185.5 0.1 5.5e-35 121.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP65696.1 - 3.3e-37 128.2 0.0 5.4e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP65696.1 - 7.2e-05 22.2 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJP65696.1 - 0.035 14.0 3.4 0.13 12.1 0.1 3.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF3896 PF13035.6 EJP65696.1 - 0.43 10.8 7.6 0.41 10.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) DUF5486 PF17588.2 EJP65696.1 - 0.49 10.3 3.4 0.22 11.5 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5486) BTB PF00651.31 EJP65697.1 - 9.7e-26 90.2 0.5 4.2e-12 46.3 0.2 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 EJP65697.1 - 3.6e-08 33.8 0.1 9.1e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP65697.1 - 1.5e-07 31.6 0.0 6.7e-06 26.3 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP65697.1 - 2.3e-07 31.3 0.0 6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP65697.1 - 3.4e-05 23.9 0.5 0.17 12.5 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EJP65697.1 - 8.5e-05 22.8 0.3 0.031 14.7 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat SUIM_assoc PF16619.5 EJP65697.1 - 0.00025 21.0 0.1 0.00084 19.4 0.0 1.9 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Choline_kinase PF01633.20 EJP65698.1 - 3.6e-58 196.6 0.0 6.9e-58 195.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EJP65698.1 - 5.5e-19 67.6 0.2 2.2e-18 65.7 0.0 2.2 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.23 EJP65698.1 - 0.00014 21.9 0.2 0.00014 21.9 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Hydrolase_6 PF13344.6 EJP65699.1 - 7.9e-21 74.1 0.0 2.7e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP65699.1 - 2e-20 72.6 0.0 6.5e-20 71.0 0.0 2.0 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EJP65699.1 - 6.9e-07 29.8 0.0 5.3 7.3 0.0 4.2 3 1 1 4 4 4 4 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EJP65699.1 - 0.24 11.4 0.0 12 5.9 0.0 2.7 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase SCO1-SenC PF02630.14 EJP65700.1 - 3.5e-48 162.9 0.0 5e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EJP65700.1 - 0.0094 15.9 0.0 0.032 14.1 0.0 1.9 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EJP65700.1 - 0.096 12.4 0.0 1.5 8.5 0.0 2.1 1 1 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 EJP65700.1 - 0.18 12.1 0.0 0.78 10.1 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like PHD PF00628.29 EJP65701.1 - 9.2e-11 41.5 10.8 9.2e-11 41.5 10.8 1.9 2 0 0 2 2 2 1 PHD-finger WD40 PF00400.32 EJP65702.1 - 3.7e-15 56.1 10.0 0.0058 17.4 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP65702.1 - 1e-05 25.7 0.1 0.37 11.1 0.0 4.4 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EJP65702.1 - 0.034 12.7 0.0 0.06 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Caskin1-CID PF16600.5 EJP65702.1 - 4.4 7.9 7.9 0.26 11.9 1.1 2.6 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain GDC-P PF02347.16 EJP65703.1 - 2.5e-161 537.3 0.0 1.1e-149 498.9 0.0 2.5 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EJP65703.1 - 3.2e-06 26.6 0.0 6.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EJP65703.1 - 0.071 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Tom5 PF10642.9 EJP65704.1 - 3.8e-21 74.8 1.9 4.1e-21 74.7 1.9 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 EJP65705.1 - 1.6e-36 125.5 1.4 1.6e-36 125.5 1.4 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EJP65705.1 - 2e-15 56.0 2.3 4.2e-15 55.0 2.3 1.6 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Adhesin_P1_N PF18652.1 EJP65705.1 - 0.013 15.5 0.8 0.028 14.4 0.8 1.6 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain YliH PF10799.8 EJP65705.1 - 0.082 12.8 0.2 0.22 11.5 0.2 1.7 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) DUF4407 PF14362.6 EJP65705.1 - 0.1 11.9 6.1 0.89 8.8 4.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DivIVA PF05103.13 EJP65705.1 - 0.25 11.5 5.0 0.33 11.0 1.3 2.3 1 1 1 2 2 2 0 DivIVA protein Nucleoporin_FG PF13634.6 EJP65705.1 - 0.29 12.0 11.0 0.48 11.3 11.0 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region CLZ PF16526.5 EJP65705.1 - 0.99 9.8 8.3 1.9 8.9 0.5 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 EJP65705.1 - 2.1 6.8 7.4 3.1 6.2 7.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family BMFP PF04380.13 EJP65705.1 - 2.7 8.6 9.2 5.1 7.7 0.1 3.1 3 0 0 3 3 3 0 Membrane fusogenic activity GAS PF13851.6 EJP65705.1 - 4 6.7 10.3 0.9 8.8 1.7 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Nbl1_Borealin_N PF10444.9 EJP65705.1 - 5.5 6.7 7.9 2.4 7.9 0.7 3.0 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Spc24 PF08286.11 EJP65705.1 - 6.5 7.0 10.0 13 6.1 3.1 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Exonuc_VII_L PF02601.15 EJP65705.1 - 7.2 6.1 7.6 74 2.8 7.8 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit CHCH PF06747.13 EJP65706.1 - 2.3e-08 34.0 13.3 8.3e-07 29.0 3.4 2.7 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 EJP65706.1 - 0.00087 19.3 5.1 0.22 11.5 1.2 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EJP65706.1 - 0.002 18.1 9.4 0.098 12.7 0.6 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EJP65706.1 - 0.038 14.3 7.9 1.4 9.2 2.9 2.7 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 CAP PF00188.26 EJP65708.1 - 1.3e-18 68.0 1.3 1.9e-18 67.5 1.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PRCC PF10253.9 EJP65708.1 - 0.07 13.9 7.0 0.086 13.6 7.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3237 PF11578.8 EJP65710.1 - 1.5e-22 80.0 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Rpp20 PF12328.8 EJP65711.1 - 2.4e-30 105.3 1.1 3.2e-30 104.9 1.1 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EJP65711.1 - 1.9e-09 37.2 0.0 4.7e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Alba Zn_clus PF00172.18 EJP65712.1 - 6.2e-07 29.4 11.5 1e-06 28.7 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lon_C PF05362.13 EJP65713.1 - 3.7e-66 222.6 0.9 6.5e-66 221.8 0.9 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EJP65713.1 - 3.3e-27 95.7 0.0 6.3e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EJP65713.1 - 6.9e-23 81.5 0.0 1.4e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EJP65713.1 - 7.3e-08 32.5 0.0 1.9e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EJP65713.1 - 3.2e-07 30.2 0.0 7.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EJP65713.1 - 1.8e-06 28.4 0.1 1.4e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EJP65713.1 - 1.8e-05 24.6 0.0 0.00014 21.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.11 EJP65713.1 - 4.8e-05 23.2 0.0 0.00017 21.4 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EJP65713.1 - 4.9e-05 23.5 0.0 0.00018 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EJP65713.1 - 5.7e-05 22.9 0.0 0.00036 20.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EJP65713.1 - 7e-05 23.1 0.0 0.0062 16.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EJP65713.1 - 0.0017 17.7 0.1 0.0043 16.3 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 EJP65713.1 - 0.0047 17.1 0.3 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EJP65713.1 - 0.028 14.3 0.4 0.083 12.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EJP65713.1 - 0.029 14.8 0.0 0.1 13.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EJP65713.1 - 0.041 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EJP65713.1 - 0.05 12.8 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 EJP65713.1 - 0.053 12.9 0.2 0.14 11.6 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EJP65713.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EJP65713.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EJP65713.1 - 0.081 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EJP65713.1 - 0.089 12.5 0.1 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJP65713.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EJP65713.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.8 1 1 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 EJP65713.1 - 0.13 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_PrkA PF08298.11 EJP65713.1 - 0.14 11.1 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_17 PF13207.6 EJP65713.1 - 0.23 11.9 1.7 1.1 9.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EJP65713.1 - 0.24 11.9 0.0 0.24 11.9 0.0 3.0 2 1 1 3 3 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.17 EJP65714.1 - 1.3e-83 280.6 0.5 4.7e-83 278.7 0.5 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EJP65714.1 - 2.2e-67 226.4 0.8 5.4e-67 225.2 0.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EJP65714.1 - 4.9e-38 131.2 1.6 9.6e-37 127.0 0.3 3.1 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EJP65714.1 - 2.4e-29 102.3 0.0 1e-28 100.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EJP65714.1 - 4.1e-17 62.1 2.3 8e-17 61.2 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RPA_C PF08784.11 EJP65714.1 - 3.1e-15 56.7 3.5 4.4e-15 56.2 0.0 3.4 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EJP65714.1 - 3.2e-08 33.5 0.1 1.1e-07 31.7 0.1 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain End3 PF12761.7 EJP65715.1 - 2.5e-76 256.3 4.6 3.5e-76 255.8 4.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EJP65715.1 - 1e-47 160.4 0.0 1.4e-46 156.7 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EJP65715.1 - 8e-07 28.2 0.4 2.6e-06 26.6 0.4 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EJP65715.1 - 4.4e-05 23.8 0.2 0.00026 21.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EJP65715.1 - 0.00064 19.5 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EJP65715.1 - 0.0013 18.5 0.2 0.013 15.4 0.3 2.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 EJP65715.1 - 0.078 12.5 0.2 0.23 11.0 0.2 1.9 1 0 0 1 1 1 0 EF hand DUF4201 PF13870.6 EJP65715.1 - 0.38 10.5 8.3 2.3 7.9 8.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) EMP24_GP25L PF01105.24 EJP65715.1 - 2.2 8.2 4.6 9.9 6.1 0.1 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Pyr_redox_2 PF07992.14 EJP65716.1 - 4.6e-34 118.0 1.0 5.7e-34 117.7 1.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP65716.1 - 1.7e-05 24.2 0.1 4.8e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EJP65716.1 - 5.4e-05 23.7 0.6 0.00087 19.8 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP65716.1 - 0.021 14.8 5.5 5.4 7.0 0.1 3.9 4 0 0 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EJP65716.1 - 0.036 14.3 1.0 10 6.4 0.1 3.3 3 0 0 3 3 3 0 TrkA-N domain Amino_oxidase PF01593.24 EJP65716.1 - 0.16 11.2 1.2 0.43 9.8 0.1 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EJP65716.1 - 0.16 11.0 2.0 7.5 5.5 0.2 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein ACBP PF00887.19 EJP65717.1 - 1.1e-13 51.2 0.3 1.4e-13 50.8 0.3 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein zinc_ribbon_4 PF13717.6 EJP65717.1 - 0.21 11.5 0.0 6.8 6.7 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Tachystatin_B PF11478.8 EJP65718.1 - 0.089 12.7 5.5 0.22 11.5 5.5 1.7 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Bromodomain PF00439.25 EJP65719.1 - 9.7e-17 60.8 0.0 2.2e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 EJP65719.1 - 0.0026 18.0 0.0 0.0048 17.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 EJP65720.1 - 2e-123 403.2 13.1 2.4e-16 60.1 0.0 12.5 2 1 15 17 17 17 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP65720.1 - 2.2e-75 248.1 18.0 4.2e-09 36.8 0.1 17.1 10 4 9 19 19 19 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP65720.1 - 3.7e-71 226.6 14.7 5.4e-05 23.3 0.0 20.4 22 0 0 22 22 22 15 Ankyrin repeat Ank_5 PF13857.6 EJP65720.1 - 2.1e-62 206.3 23.1 4e-11 42.9 0.0 14.8 9 3 7 16 16 16 13 Ankyrin repeats (many copies) Ank PF00023.30 EJP65720.1 - 9.3e-62 202.9 30.0 0.00021 21.6 0.1 19.3 20 1 1 21 21 21 13 Ankyrin repeat F-box PF00646.33 EJP65720.1 - 0.071 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EJP65720.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 EJP65720.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 F-box NUDIX PF00293.28 EJP65722.1 - 1.8e-26 92.7 0.0 2.7e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Rad51 PF08423.11 EJP65723.1 - 1.9e-10 40.5 0.0 7.7e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 EJP65723.1 - 1.3e-08 34.5 0.0 2.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 KaiC RecA PF00154.21 EJP65723.1 - 5.4e-07 29.3 0.1 6.6e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EJP65723.1 - 3.7e-05 23.4 0.1 0.00014 21.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP65723.1 - 6e-05 23.5 0.0 0.00016 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 EJP65723.1 - 0.00011 21.7 0.1 0.067 12.5 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 EJP65723.1 - 0.00031 20.7 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EJP65723.1 - 0.0013 19.3 0.0 0.0021 18.6 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EJP65723.1 - 0.0014 18.9 0.0 0.0044 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EJP65723.1 - 0.0039 16.7 0.1 0.0079 15.7 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.6 EJP65723.1 - 0.0055 16.9 0.4 0.032 14.4 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EJP65723.1 - 0.0066 16.9 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EJP65723.1 - 0.0091 15.7 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.6 EJP65723.1 - 0.018 14.8 0.1 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EJP65723.1 - 0.028 14.1 0.0 0.077 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EJP65723.1 - 0.031 14.8 0.0 0.29 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJP65723.1 - 0.056 13.8 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 1 0 RNA helicase NACHT PF05729.12 EJP65723.1 - 0.063 13.2 0.3 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 EJP65723.1 - 0.063 13.3 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EJP65723.1 - 0.071 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EJP65723.1 - 0.072 13.3 0.3 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Glyoxalase PF00903.25 EJP65724.1 - 6.2e-07 29.7 0.2 1.3e-06 28.6 0.2 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EJP65724.1 - 0.042 14.6 0.2 0.065 14.0 0.2 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain zf-H2C2_2 PF13465.6 EJP65725.1 - 7.6e-09 35.6 24.9 1.8e-05 24.9 3.5 4.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EJP65725.1 - 2.1e-06 27.9 21.0 0.00041 20.6 4.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EJP65725.1 - 0.019 15.3 3.0 0.049 13.9 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EJP65725.1 - 0.047 14.5 3.1 0.047 14.5 3.1 4.5 5 0 0 5 5 5 0 C2H2-type zinc finger DUF2225 PF09986.9 EJP65725.1 - 0.39 10.4 0.7 0.79 9.4 0.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) FOXP-CC PF16159.5 EJP65725.1 - 1.4 9.6 9.6 0.31 11.7 2.6 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain TIM21 PF08294.11 EJP65726.1 - 6.3e-46 155.9 0.0 7.7e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EJP65726.1 - 0.063 13.0 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.18 EJP65727.1 - 1.5e-34 118.5 0.3 2.7e-34 117.7 0.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf YhfH PF14149.6 EJP65727.1 - 0.048 13.6 0.4 0.11 12.5 0.4 1.6 1 0 0 1 1 1 0 YhfH-like protein NMO PF03060.15 EJP65728.1 - 2.1e-56 191.7 4.0 2.7e-56 191.4 4.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EJP65728.1 - 2.7e-12 46.4 4.0 3.8e-12 45.9 4.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EJP65728.1 - 3e-05 23.2 3.4 5.3e-05 22.4 3.4 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 EJP65728.1 - 0.0017 17.6 0.3 0.0026 17.0 0.3 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 EJP65728.1 - 0.013 14.7 0.1 0.032 13.4 0.1 1.7 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 EJP65728.1 - 0.019 14.1 0.6 0.04 13.1 0.6 1.6 1 0 0 1 1 1 0 Conserved region in glutamate synthase Pterin_bind PF00809.22 EJP65729.1 - 2.9e-62 210.5 0.1 1.7e-44 152.4 0.2 2.2 1 1 1 2 2 2 2 Pterin binding enzyme HPPK PF01288.20 EJP65729.1 - 3.1e-36 124.3 0.0 7.2e-36 123.1 0.0 1.6 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NDT80_PhoG PF05224.12 EJP65730.1 - 1.2e-31 110.3 0.0 2.9e-31 109.1 0.0 1.6 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ABC_tran PF00005.27 EJP65732.1 - 1.9e-43 148.3 1.6 2.6e-20 73.3 0.0 3.4 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EJP65732.1 - 9.4e-12 45.3 9.9 0.0017 18.2 0.5 4.5 4 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP65732.1 - 2.7e-11 43.3 0.0 0.00012 21.6 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 EJP65732.1 - 7.9e-10 38.6 6.0 7.9e-10 38.6 6.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.6 EJP65732.1 - 9.4e-08 31.7 0.4 0.00084 19.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJP65732.1 - 1e-07 32.0 0.4 0.033 14.3 0.0 4.0 4 1 1 5 5 5 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EJP65732.1 - 3.2e-07 30.7 0.1 0.00062 20.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EJP65732.1 - 4e-06 26.7 1.8 0.039 13.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EJP65732.1 - 4.8e-06 26.9 0.2 0.16 12.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EJP65732.1 - 9.2e-06 26.2 0.5 0.13 12.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 EJP65732.1 - 1.1e-05 24.6 0.6 0.011 14.7 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EJP65732.1 - 3.5e-05 24.2 2.9 0.19 12.1 0.6 2.8 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EJP65732.1 - 4.3e-05 23.5 2.5 0.18 11.7 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_33 PF13671.6 EJP65732.1 - 6.7e-05 23.1 2.6 0.94 9.6 0.2 3.8 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 EJP65732.1 - 0.00013 22.4 0.0 0.12 12.8 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EJP65732.1 - 0.00017 21.5 0.1 0.062 13.2 0.0 2.9 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.17 EJP65732.1 - 0.00018 21.7 4.2 0.18 11.9 0.1 3.3 3 0 0 3 3 3 2 Helicase HerA, central domain Dynamin_N PF00350.23 EJP65732.1 - 0.001 19.2 1.2 1.9 8.5 0.0 3.2 3 0 0 3 3 3 2 Dynamin family DUF815 PF05673.13 EJP65732.1 - 0.0021 17.3 0.9 0.55 9.3 0.0 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EJP65732.1 - 0.0039 17.6 0.0 0.86 10.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 EJP65732.1 - 0.0042 17.1 0.1 4.7 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 EJP65732.1 - 0.0064 16.9 6.2 5.6 7.4 0.0 4.4 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EJP65732.1 - 0.0069 16.3 0.4 1.9 8.4 0.0 3.1 3 0 0 3 3 3 1 NTPase Arf PF00025.21 EJP65732.1 - 0.0085 15.6 0.2 0.3 10.5 0.0 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_15 PF13175.6 EJP65732.1 - 0.0089 15.8 5.2 0.058 13.1 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_7 PF12775.7 EJP65732.1 - 0.016 14.7 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_ATPase PF09818.9 EJP65732.1 - 0.022 13.5 0.0 0.022 13.5 0.0 2.3 4 0 0 4 4 4 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 EJP65732.1 - 0.027 14.1 0.1 3.7 7.2 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Thymidylate_kin PF02223.17 EJP65732.1 - 0.037 13.7 2.7 1.3 8.7 0.0 3.0 3 0 0 3 3 2 0 Thymidylate kinase AAA_24 PF13479.6 EJP65732.1 - 0.044 13.5 4.3 2.6 7.7 0.0 3.5 4 0 0 4 4 4 0 AAA domain MobB PF03205.14 EJP65732.1 - 0.046 13.6 0.5 19 5.1 0.1 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B VHS PF00790.19 EJP65732.1 - 0.051 13.4 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 1 0 VHS domain TsaE PF02367.17 EJP65732.1 - 0.053 13.5 0.2 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EJP65732.1 - 0.055 13.2 0.2 8.1 6.1 0.0 2.9 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 EJP65732.1 - 0.058 13.9 21.4 0.6 10.6 4.3 3.7 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 EJP65732.1 - 0.07 12.7 0.3 16 5.0 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EJP65732.1 - 0.082 13.1 2.8 9.6 6.5 0.0 3.1 3 1 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 EJP65732.1 - 0.095 12.7 1.6 1.4 8.9 0.2 3.4 4 1 1 5 5 4 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 EJP65732.1 - 0.2 10.3 8.4 5 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 EJP65732.1 - 0.24 11.0 5.8 0.26 10.9 0.0 2.9 3 1 0 3 3 2 0 AAA domain NB-ARC PF00931.22 EJP65732.1 - 0.28 10.4 8.3 1.5 7.9 0.0 3.8 4 0 0 4 4 4 0 NB-ARC domain ATPase_2 PF01637.18 EJP65732.1 - 0.47 10.3 2.5 11 5.9 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EJP65732.1 - 1.3 8.5 4.0 1.4 8.4 0.1 2.8 4 0 0 4 4 2 0 AAA domain DAGK_cat PF00781.24 EJP65733.1 - 2.7e-08 33.5 0.0 5.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3459 PF11941.8 EJP65733.1 - 0.11 12.8 0.9 1.1 9.6 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) TRM PF02005.16 EJP65734.1 - 2.8e-104 349.3 0.0 5.8e-94 315.3 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EJP65734.1 - 0.00023 21.0 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.17 EJP65734.1 - 0.0086 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase DUF1623 PF07785.11 EJP65734.1 - 0.044 13.9 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Methyltransf_15 PF09445.10 EJP65734.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Trypan_PARP PF05887.11 EJP65734.1 - 0.92 9.5 10.8 2.1 8.4 10.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SLATT_fungal PF18142.1 EJP65735.1 - 2.4e-28 98.5 0.0 3.4e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SLATT_1 PF18181.1 EJP65735.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Fringe PF02434.16 EJP65736.1 - 0.039 13.4 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Fringe-like Acetyltransf_3 PF13302.7 EJP65737.1 - 1.8e-14 54.6 0.0 2.8e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP65737.1 - 8.5e-07 29.2 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP65737.1 - 0.012 16.1 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Spo7 PF03907.13 EJP65738.1 - 7.1e-93 310.1 0.0 9.9e-93 309.7 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Na_H_Exchanger PF00999.21 EJP65738.1 - 0.032 13.0 0.1 0.047 12.5 0.1 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Abhydrolase_1 PF00561.20 EJP65739.1 - 4.8e-18 65.7 0.0 9.4e-17 61.5 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP65739.1 - 1.6e-15 57.0 0.0 7.6e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP65739.1 - 8e-13 49.5 8.3 1.3e-12 48.8 4.8 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EJP65739.1 - 4e-05 23.1 0.0 7.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EJP65739.1 - 9.2e-05 22.2 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 EJP65739.1 - 0.02 14.5 0.0 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 EJP65739.1 - 0.046 13.6 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EJP65739.1 - 0.065 13.3 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 EJP65739.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 EJP65739.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 EJP65739.1 - 0.19 11.4 0.0 0.72 9.5 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_2 PF02230.16 EJP65739.1 - 0.21 11.3 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RSN1_7TM PF02714.15 EJP65740.1 - 8e-75 251.7 25.6 8e-75 251.7 25.6 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EJP65740.1 - 2.5e-44 150.8 1.0 2.5e-44 150.8 1.0 4.1 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EJP65740.1 - 6.4e-30 104.7 1.8 1.1e-17 64.8 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EJP65740.1 - 2.9e-16 59.4 0.0 7.9e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter MIF4G_like_2 PF09090.11 EJP65740.1 - 0.049 13.1 1.6 0.1 12.1 1.6 1.5 1 0 0 1 1 1 0 MIF4G like Nodulin_late PF07127.11 EJP65740.1 - 8.3 6.8 8.5 64 4.0 6.4 2.9 2 0 0 2 2 2 0 Late nodulin protein CYSTM PF12734.7 EJP65741.1 - 0.009 16.3 33.1 0.009 16.3 33.1 5.6 2 2 0 2 2 2 1 Cysteine-rich TM module stress tolerance eIF3g PF12353.8 EJP65742.1 - 3.9e-44 150.0 1.6 6.5e-44 149.3 1.6 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EJP65742.1 - 7.3e-15 54.5 0.1 1.4e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 EJP65742.1 - 0.023 15.0 0.2 0.046 14.1 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 PEMT PF04191.13 EJP65743.1 - 5.3e-57 190.8 15.4 5.3e-36 123.2 2.1 2.9 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 EJP65743.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 EJP65743.1 - 0.041 14.4 0.0 1.9 9.1 0.0 2.3 2 0 0 2 2 2 0 SKICH domain Lactonase PF10282.9 EJP65744.1 - 2e-79 267.3 0.0 2.4e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 EJP65744.1 - 0.097 12.6 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Zn_clus PF00172.18 EJP65745.1 - 8.5e-10 38.6 8.1 8.5e-10 38.6 8.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.21 EJP65747.1 - 0.0016 18.7 1.7 0.0027 17.9 1.7 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-like PF04071.12 EJP65747.1 - 0.028 14.3 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 Cysteine-rich small domain DUF676 PF05057.14 EJP65748.1 - 6.4e-43 146.8 0.1 2.2e-27 96.0 0.0 3.2 2 1 0 2 2 2 2 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EJP65748.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Glyco_hydro_72 PF03198.14 EJP65749.1 - 1.3e-114 382.7 4.3 1.7e-114 382.3 4.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EJP65749.1 - 1.5e-17 64.0 3.7 1.5e-17 64.0 3.7 2.4 3 0 0 3 3 3 1 X8 domain Cellulase PF00150.18 EJP65749.1 - 0.0018 17.7 0.3 0.013 14.9 0.3 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4501 PF14946.6 EJP65749.1 - 0.0072 16.4 0.4 0.021 14.9 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) Mit_KHE1 PF10173.9 EJP65750.1 - 1.4e-59 201.4 0.0 2.6e-59 200.5 0.0 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Svf1_C PF17187.4 EJP65751.1 - 1.3e-59 200.7 0.0 2.5e-59 199.8 0.0 1.5 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EJP65751.1 - 8.7e-57 191.7 0.0 1.2e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain GATA PF00320.27 EJP65752.1 - 1.4e-14 53.4 4.5 1.5e-14 53.3 2.0 2.1 2 0 0 2 2 2 1 GATA zinc finger ArfGap PF01412.18 EJP65752.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf ADIP PF11559.8 EJP65752.1 - 0.11 12.6 12.1 0.24 11.5 12.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TF_Zn_Ribbon PF08271.12 EJP65752.1 - 0.14 11.7 0.6 0.27 10.8 0.6 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding CENP-F_leu_zip PF10473.9 EJP65752.1 - 0.16 12.0 18.0 0.14 12.2 4.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fmp27_WPPW PF10359.9 EJP65752.1 - 0.58 9.0 9.0 0.89 8.3 9.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4226 PF10774.9 EJP65752.1 - 0.62 10.4 8.3 0.19 12.0 5.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Atg14 PF10186.9 EJP65752.1 - 0.75 8.8 8.8 1.4 7.9 8.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 EJP65752.1 - 1.3 9.6 21.9 0.03 14.8 15.0 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region TFIID-31kDa PF02291.15 EJP65753.1 - 0.046 13.8 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 EJP65753.1 - 0.1 12.6 0.2 0.16 12.0 0.1 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Collagen PF01391.18 EJP65755.1 - 0.0022 17.7 5.0 0.0031 17.2 5.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_M48_N PF16491.5 EJP65756.1 - 5.5e-48 163.3 1.6 5.5e-48 163.3 1.6 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EJP65756.1 - 5.1e-39 134.1 0.6 7.7e-39 133.5 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EJP65756.1 - 0.044 13.0 1.8 0.052 12.7 0.1 2.1 3 0 0 3 3 3 0 BlaR1 peptidase M56 Acetyltransf_1 PF00583.25 EJP65757.1 - 1.3e-06 28.7 0.0 2.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP65757.1 - 0.0093 16.4 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EJP65757.1 - 0.0094 15.7 0.8 0.022 14.5 0.6 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_10 PF13673.7 EJP65757.1 - 0.017 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain APH PF01636.23 EJP65758.1 - 1.1e-06 28.7 0.6 1.5e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Defensin_RK-1 PF17860.1 EJP65758.1 - 0.00083 19.8 0.1 0.0019 18.7 0.1 1.5 1 0 0 1 1 1 1 RK-1-like defensin EcKinase PF02958.20 EJP65758.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase FmdA_AmdA PF03069.15 EJP65759.1 - 4.6e-55 187.0 0.0 9.3e-33 113.6 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family MOSC PF03473.17 EJP65760.1 - 4.3e-28 97.9 0.0 6.5e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EJP65760.1 - 1.5e-08 34.5 0.0 2.8e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Glyco_hydro_47 PF01532.20 EJP65761.1 - 1.1e-143 479.5 0.0 1.3e-143 479.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 p450 PF00067.22 EJP65762.1 - 7.8e-59 199.6 0.0 1e-58 199.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terminase_GpA PF05876.12 EJP65764.1 - 0.012 14.2 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) ketoacyl-synt PF00109.26 EJP65765.1 - 1.5e-67 227.9 0.0 3.5e-67 226.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EJP65765.1 - 1.7e-65 221.5 0.1 2.8e-65 220.8 0.1 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 EJP65765.1 - 6.2e-65 219.4 0.0 1.2e-64 218.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.10 EJP65765.1 - 2.5e-45 154.6 0.2 3.5e-42 144.3 0.0 3.1 3 0 0 3 3 3 2 KR domain PS-DH PF14765.6 EJP65765.1 - 5.6e-44 150.6 0.0 9.5e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EJP65765.1 - 5.8e-40 137.7 0.0 1.5e-39 136.4 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP65765.1 - 3.6e-30 104.4 0.0 9.2e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EJP65765.1 - 1.1e-27 96.9 0.0 2e-26 92.7 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EJP65765.1 - 1.1e-16 60.9 0.7 3.5e-07 30.5 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EJP65765.1 - 7.4e-15 55.4 0.5 2.5e-13 50.5 0.0 3.1 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EJP65765.1 - 6.7e-11 42.1 0.0 5.7e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EJP65765.1 - 1.2e-08 34.6 0.0 1.5e-06 27.8 0.0 3.3 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_12 PF08242.12 EJP65765.1 - 7.6e-07 29.8 0.0 3.1e-06 27.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP65765.1 - 9.1e-07 28.9 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EJP65765.1 - 5.9e-05 22.7 0.0 0.00034 20.2 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.6 EJP65765.1 - 0.00013 22.5 0.1 0.00069 20.3 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP65765.1 - 0.00031 21.3 0.0 0.001 19.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EJP65765.1 - 0.0004 19.9 0.0 0.092 12.1 0.0 2.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EJP65765.1 - 0.0012 18.3 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 EJP65765.1 - 0.0052 16.6 0.0 0.033 14.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.19 EJP65765.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 EJP65765.1 - 0.021 14.1 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 EJP65766.1 - 2.6e-10 40.4 0.1 6.2e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP65766.1 - 2.8e-07 30.4 0.0 9.4e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.18 EJP65767.1 - 1.7e-08 34.5 12.4 2.8e-08 33.8 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP65767.1 - 2.9e-07 29.7 0.2 2.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain AMP-binding PF00501.28 EJP65768.1 - 5.8e-60 203.1 0.0 9.1e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EJP65768.1 - 7.3e-16 57.9 0.0 1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 EJP65768.1 - 4.4e-07 30.8 0.1 1.8e-06 28.8 0.1 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 EJP65768.1 - 0.00062 20.1 0.1 0.0019 18.5 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site CRAL_TRIO_2 PF13716.6 EJP65769.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain K1 PF02960.14 EJP65769.1 - 1.5 8.9 4.4 0.87 9.7 0.2 2.6 2 1 1 3 3 3 0 K1 glycoprotein DUF5336 PF17270.2 EJP65769.1 - 2.9 7.5 13.7 2.7 7.6 0.4 2.7 1 1 2 3 3 3 0 Family of unknown function (DUF5336) Abhydrolase_1 PF00561.20 EJP65770.1 - 1.9e-08 34.3 0.1 3.5e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP65770.1 - 3.4e-08 34.3 0.9 5.3e-08 33.7 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EJP65770.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase AAA PF00004.29 EJP65771.1 - 9.3e-17 61.7 0.0 1.5e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Glyco_hydro_3_C PF01915.22 EJP65772.1 - 2.8e-43 148.3 0.0 6.6e-43 147.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EJP65772.1 - 5.3e-35 121.3 0.0 1e-34 120.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EJP65772.1 - 2.4e-23 82.0 0.0 4e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Trypsin PF00089.26 EJP65773.1 - 4.9e-42 144.2 0.5 5.7e-42 144.0 0.5 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP65773.1 - 7.2e-07 30.2 0.8 1.6e-06 29.1 0.8 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain LRR_9 PF14580.6 EJP65775.1 - 5.6e-54 182.3 0.0 8.9e-54 181.6 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EJP65775.1 - 1.2e-07 31.9 4.8 0.00044 20.6 0.7 3.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EJP65775.1 - 3.6e-06 26.6 0.1 1.3e-05 24.9 0.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat DUF4349 PF14257.6 EJP65775.1 - 0.0095 15.4 2.2 0.017 14.5 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) DUF5535 PF17687.1 EJP65775.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5535) CBFD_NFYB_HMF PF00808.23 EJP65776.1 - 2e-14 53.6 0.6 3.2e-14 53.0 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EJP65776.1 - 0.00024 21.4 0.1 0.00056 20.3 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Voltage_CLC PF00654.20 EJP65777.1 - 6e-89 298.7 27.2 6e-89 298.7 27.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EJP65777.1 - 2.9e-13 50.0 0.0 2.4e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain EamA PF00892.20 EJP65778.1 - 4.6e-05 23.6 11.8 0.00013 22.1 11.8 1.7 1 1 0 1 1 1 1 EamA-like transporter family TFIIA_gamma_C PF02751.14 EJP65779.1 - 7.4e-24 83.6 0.9 1.1e-23 83.1 0.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EJP65779.1 - 9.5e-24 83.2 0.3 1.3e-23 82.7 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF570 PF04489.13 EJP65779.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF570) HHH_4 PF14490.6 EJP65779.1 - 0.13 12.2 0.0 0.5 10.4 0.0 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix containing domain PspB PF06667.12 EJP65780.1 - 0.069 13.2 0.8 0.35 11.0 0.2 2.0 2 0 0 2 2 2 0 Phage shock protein B ATP-synt_C PF00137.21 EJP65782.1 - 9.1e-25 86.8 37.4 3.9e-15 55.9 12.3 2.7 3 1 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 EJP65782.1 - 0.088 12.1 0.1 0.088 12.1 0.1 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3671 PF12420.8 EJP65782.1 - 0.76 9.9 3.3 0.88 9.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF981 PF06168.11 EJP65782.1 - 4.5 7.1 21.2 0.69 9.8 7.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF981) MoCF_biosynth PF00994.24 EJP65783.1 - 1.8e-54 183.4 1.4 4.3e-28 97.8 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EJP65783.1 - 2.6e-39 134.5 3.6 4.4e-39 133.8 3.6 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EJP65783.1 - 2.1e-13 50.2 0.6 7.5e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 EJP65783.1 - 6.5 6.1 17.3 10 5.4 17.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region EF-hand_1 PF00036.32 EJP65784.1 - 5.3e-25 85.1 11.7 8.3e-08 31.3 0.2 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EJP65784.1 - 1.2e-24 84.1 4.5 2.7e-06 26.9 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 EJP65784.1 - 5.9e-24 84.3 9.8 1.8e-15 57.1 1.5 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EJP65784.1 - 4.3e-16 57.6 14.1 0.00031 20.1 0.5 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EJP65784.1 - 9.6e-15 54.2 8.9 3.6e-05 23.5 0.4 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EJP65784.1 - 1.4e-08 34.6 5.9 0.0067 16.4 0.3 3.9 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EJP65784.1 - 0.00023 21.4 1.1 0.079 13.3 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EJP65784.1 - 0.0019 18.5 2.1 1.5 9.2 0.6 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 EJP65784.1 - 0.014 14.3 0.3 1.5 7.6 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.11 EJP65784.1 - 0.017 15.3 0.3 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 EF hand EF-hand_10 PF14788.6 EJP65784.1 - 0.051 13.4 1.5 0.54 10.2 0.1 3.1 4 0 0 4 4 4 0 EF hand Caleosin PF05042.13 EJP65784.1 - 0.27 11.1 2.5 11 5.9 0.0 3.3 2 1 2 4 4 4 0 Caleosin related protein Methyltransf_16 PF10294.9 EJP65785.1 - 1.3e-12 47.9 0.0 2.4e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Fungal_trans PF04082.18 EJP65786.1 - 1.1e-19 70.6 0.0 1.7e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65786.1 - 5.8e-10 39.1 12.7 9.7e-10 38.4 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_33 PF10017.9 EJP65786.1 - 0.015 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent MFS_1 PF07690.16 EJP65787.1 - 1.2e-44 152.8 45.9 3.2e-44 151.3 45.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP65787.1 - 8.8e-14 51.2 5.4 8.8e-14 51.2 5.4 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EJP65787.1 - 4.3e-11 42.0 13.4 7.6e-11 41.1 13.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5337 PF17272.2 EJP65787.1 - 0.11 12.3 2.2 0.61 10.0 2.2 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5337) JAB PF01398.21 EJP65788.1 - 8.3e-08 32.2 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EJP65788.1 - 3.1e-07 30.8 0.0 6.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Vps5 PF09325.10 EJP65789.1 - 1.5e-10 41.1 0.9 2.2e-10 40.5 0.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EJP65789.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 PX domain NST1 PF13945.6 EJP65789.1 - 0.032 14.3 3.4 0.059 13.5 3.4 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator BCIP PF13862.6 EJP65790.1 - 6.5e-68 228.6 0.5 8.1e-68 228.3 0.5 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DEC-1_C PF04626.13 EJP65790.1 - 0.0081 16.6 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Dec-1 protein, C terminal region IBR PF01485.21 EJP65793.1 - 7.9e-06 26.0 4.7 7.9e-06 26.0 4.7 4.3 5 0 0 5 5 5 3 IBR domain, a half RING-finger domain Mito_carr PF00153.27 EJP65794.1 - 5.9e-55 183.2 2.9 3e-18 65.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein G-alpha PF00503.20 EJP65796.1 - 2.4e-116 388.8 1.6 2.8e-116 388.6 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EJP65796.1 - 1.1e-15 57.6 0.6 6.2e-10 38.8 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJP65796.1 - 0.00016 21.1 2.5 0.022 14.1 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EJP65796.1 - 0.0087 16.3 0.6 1.4 9.2 0.2 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EJP65796.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.20 EJP65797.1 - 0 1040.0 0.0 0 1039.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 EJP65798.1 - 3.7e-68 229.7 0.0 4.6e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP65798.1 - 1.5e-32 112.9 0.0 3.2e-32 111.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJP65798.1 - 9.5e-06 24.8 0.1 1.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EJP65798.1 - 3.3e-05 23.3 0.1 0.0001 21.7 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP65798.1 - 0.00043 20.3 0.1 0.0018 18.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP65798.1 - 0.00079 18.8 0.0 0.051 12.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EJP65798.1 - 0.024 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EJP65798.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ABC_tran PF00005.27 EJP65799.1 - 5.9e-51 172.6 0.1 9.9e-29 100.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP65799.1 - 2.5e-37 129.0 32.8 3.3e-21 76.2 13.9 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP65799.1 - 4.2e-09 36.2 2.8 0.032 13.7 1.0 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP65799.1 - 2.2e-08 34.9 0.5 1.5e-05 25.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 EJP65799.1 - 2.4e-08 33.6 1.4 0.0018 18.0 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP65799.1 - 1.8e-06 28.0 0.2 0.0031 17.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EJP65799.1 - 2.1e-06 27.8 0.1 0.023 14.5 0.1 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EJP65799.1 - 8.5e-06 25.5 0.1 0.17 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJP65799.1 - 9.2e-06 26.1 0.2 0.14 12.5 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EJP65799.1 - 2.3e-05 24.4 0.1 0.052 13.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EJP65799.1 - 5.2e-05 23.5 1.0 0.44 10.8 0.1 3.2 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 EJP65799.1 - 8.5e-05 22.7 2.7 0.0053 16.9 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 EJP65799.1 - 0.00011 22.3 2.1 0.14 12.2 0.0 2.7 3 0 0 3 3 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 EJP65799.1 - 0.0005 19.5 0.2 0.41 10.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family NB-ARC PF00931.22 EJP65799.1 - 0.0007 18.9 1.4 1.3 8.1 0.0 3.9 4 0 0 4 4 4 1 NB-ARC domain NACHT PF05729.12 EJP65799.1 - 0.0013 18.7 0.6 1.1 9.2 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 EJP65799.1 - 0.0026 17.9 0.0 3.5 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EJP65799.1 - 0.0061 15.6 1.4 0.69 8.9 0.2 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.19 EJP65799.1 - 0.0067 16.0 0.5 1.4 8.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EJP65799.1 - 0.0078 16.1 0.8 2.8 7.8 0.1 2.4 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 EJP65799.1 - 0.0089 15.8 0.1 0.57 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EJP65799.1 - 0.018 15.3 0.2 6.8 7.0 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Viral_helicase1 PF01443.18 EJP65799.1 - 0.019 14.7 0.1 8.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.18 EJP65799.1 - 0.031 13.6 0.1 9 5.5 0.0 2.4 2 0 0 2 2 2 0 Septin Roc PF08477.13 EJP65799.1 - 0.069 13.4 0.1 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EJP65799.1 - 0.078 12.5 0.3 2.2 7.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EJP65799.1 - 0.081 12.2 0.3 2.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 EJP65799.1 - 0.086 12.9 0.0 9.8 6.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 EJP65799.1 - 0.095 11.9 0.4 1 8.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AIG1 PF04548.16 EJP65799.1 - 0.1 11.9 0.3 3.7 6.8 0.1 2.2 2 0 0 2 2 2 0 AIG1 family ATP_bind_1 PF03029.17 EJP65799.1 - 0.11 12.2 2.4 5.2 6.8 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA PF00004.29 EJP65799.1 - 0.13 12.7 0.1 43 4.5 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EJP65799.1 - 0.13 12.0 0.4 2.4 7.8 0.2 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EJP65799.1 - 0.16 12.6 0.1 25 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EJP65799.1 - 0.16 12.0 0.1 16 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 EJP65799.1 - 0.16 11.4 2.7 0.69 9.3 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_24 PF13479.6 EJP65799.1 - 0.18 11.5 0.2 18 4.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EJP65799.1 - 0.18 12.2 0.1 32 5.0 0.0 3.0 3 0 0 3 3 2 0 RNA helicase DAP3 PF10236.9 EJP65799.1 - 0.2 10.8 1.6 7.8 5.6 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.9 EJP65799.1 - 3.5 6.3 5.9 3.7 6.2 0.1 3.1 4 0 0 4 4 4 0 Predicted ATPase of the ABC class ACPS PF01648.20 EJP65800.1 - 1.1e-09 38.4 0.0 1.6e-09 37.9 0.0 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EJP65800.1 - 0.0077 16.3 4.7 2.2 8.4 4.7 2.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain DUF1774 PF08611.10 EJP65801.1 - 3.3e-36 123.5 3.7 3.3e-36 123.5 3.7 2.4 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) DUF3894 PF13033.6 EJP65801.1 - 0.38 10.9 8.6 1.6 8.9 2.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3894) AAA_6 PF12774.7 EJP65802.1 - 2.5e-127 424.4 0.0 1.4e-126 421.9 0.0 2.5 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EJP65802.1 - 2.3e-117 393.0 6.6 2.3e-117 393.0 6.6 5.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EJP65802.1 - 4.4e-117 391.5 7.0 4.4e-117 391.5 7.0 5.8 4 3 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EJP65802.1 - 6.8e-74 247.7 0.7 6.8e-74 247.7 0.7 3.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 EJP65802.1 - 3e-67 226.7 0.0 1.8e-66 224.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EJP65802.1 - 4.8e-41 140.2 0.0 4.4e-36 124.1 0.0 4.7 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 EJP65802.1 - 2.3e-38 132.1 11.4 5.2e-38 130.9 11.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EJP65802.1 - 8.7e-32 110.0 0.0 7.5e-11 42.2 0.0 6.4 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 EJP65802.1 - 1.6e-29 102.9 0.0 3.9e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EJP65802.1 - 2.8e-29 101.6 0.0 7.5e-27 93.8 0.0 4.2 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EJP65802.1 - 1.7e-15 57.3 0.0 6.4e-15 55.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EJP65802.1 - 6.7e-13 49.1 8.3 0.01 16.1 0.0 7.2 7 1 0 7 7 5 3 AAA domain AAA PF00004.29 EJP65802.1 - 8e-13 49.0 0.0 0.002 18.6 0.0 4.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJP65802.1 - 2.9e-09 37.5 8.3 1.8 8.9 0.0 8.7 9 0 0 9 9 8 1 AAA ATPase domain AAA_18 PF13238.6 EJP65802.1 - 2.7e-08 34.4 0.9 0.11 13.1 0.0 5.8 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 EJP65802.1 - 2.9e-08 34.0 2.9 0.47 10.6 0.1 5.4 5 0 0 5 5 4 3 AAA domain AAA_29 PF13555.6 EJP65802.1 - 1.1e-05 25.0 0.1 0.87 9.4 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 EJP65802.1 - 6.4e-05 23.1 1.5 0.00081 19.6 0.0 3.5 3 0 0 3 3 2 1 AAA+ lid domain T2SSE PF00437.20 EJP65802.1 - 7.2e-05 22.0 0.0 0.043 12.9 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein ABC_tran PF00005.27 EJP65802.1 - 0.00033 21.2 0.9 5.5 7.5 0.0 5.2 4 0 0 4 4 3 0 ABC transporter Mg_chelatase PF01078.21 EJP65802.1 - 0.0005 19.5 1.1 0.67 9.3 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EJP65802.1 - 0.00064 19.3 0.0 0.24 10.9 0.0 3.4 2 0 0 2 2 2 1 AAA domain Taxilin PF09728.9 EJP65802.1 - 0.00084 18.6 0.9 0.00084 18.6 0.9 4.4 4 0 0 4 4 3 1 Myosin-like coiled-coil protein AAA_19 PF13245.6 EJP65802.1 - 0.001 19.4 1.1 0.28 11.5 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 EJP65802.1 - 0.0021 17.8 1.8 38 3.9 0.0 5.4 7 0 0 7 7 5 0 AAA domain AAA_24 PF13479.6 EJP65802.1 - 0.0026 17.5 0.2 9.9 5.8 0.0 4.2 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EJP65802.1 - 0.007 15.7 2.4 2.4 7.5 0.0 4.1 4 0 0 4 4 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 EJP65802.1 - 0.012 15.4 1.5 0.72 9.6 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein Hemerythrin PF01814.23 EJP65802.1 - 0.044 14.4 0.3 1.4 9.5 0.1 3.7 4 0 0 4 4 2 0 Hemerythrin HHE cation binding domain Rad17 PF03215.15 EJP65802.1 - 0.066 13.1 0.0 7 6.5 0.0 3.4 3 0 0 3 3 3 0 Rad17 P-loop domain DUF4482 PF14818.6 EJP65802.1 - 0.15 13.0 7.1 27 5.6 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Swm2 PF17083.5 EJP65802.1 - 0.34 10.9 3.3 0.57 10.2 0.1 3.2 3 0 0 3 3 1 0 Nucleolar protein Swm2 Spc7 PF08317.11 EJP65802.1 - 0.41 9.5 42.3 0.017 14.0 12.7 5.3 5 1 0 5 5 5 0 Spc7 kinetochore protein UCH PF00443.29 EJP65802.1 - 1.1 8.7 3.4 5.9 6.3 0.1 3.4 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase NACHT PF05729.12 EJP65802.1 - 4.2 7.3 5.7 31 4.4 0.0 4.0 4 0 0 4 4 3 0 NACHT domain CLZ PF16526.5 EJP65802.1 - 6.1 7.3 13.6 0.025 14.9 0.8 3.9 3 0 0 3 3 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Golgin_A5 PF09787.9 EJP65803.1 - 0.0086 15.6 3.0 0.0086 15.6 3.0 3.9 2 1 1 4 4 4 1 Golgin subfamily A member 5 Mem_trans PF03547.18 EJP65803.1 - 1.3 7.4 2.9 2.1 6.6 2.9 1.5 1 0 0 1 1 1 0 Membrane transport protein VASt PF16016.5 EJP65804.1 - 3.6e-36 124.9 0.1 6.1e-36 124.1 0.1 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EJP65804.1 - 3.7e-23 81.6 0.0 6.2e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain BUD22 PF09073.10 EJP65805.1 - 0.31 10.3 5.4 0.5 9.7 5.4 1.3 1 0 0 1 1 1 0 BUD22 TP_methylase PF00590.20 EJP65806.1 - 2.4e-23 83.2 0.0 4.2e-23 82.4 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 EJP65807.1 - 6.5e-08 32.7 0.2 1.1e-07 32.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJP65807.1 - 2.3e-05 24.6 0.5 4.1e-05 23.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 EJP65807.1 - 0.00056 19.9 1.5 0.0019 18.2 1.5 2.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 EJP65807.1 - 0.0041 17.2 0.1 0.0077 16.3 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger DNA_pol3_a_NI PF14480.6 EJP65807.1 - 0.097 12.7 0.6 0.16 12.0 0.6 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I zf-C2H2 PF00096.26 EJP65807.1 - 0.14 12.7 0.4 0.23 12.0 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Peptidase_S49_N PF08496.10 EJP65807.1 - 4 7.5 16.0 3.9 7.5 1.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal UQ_con PF00179.26 EJP65808.1 - 3.6e-34 117.4 0.0 4e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP65808.1 - 0.00017 21.3 0.0 0.00042 20.0 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B Glyco_trans_1_4 PF13692.6 EJP65809.1 - 0.00012 22.5 0.0 0.00024 21.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EJP65809.1 - 0.029 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Cation_efflux PF01545.21 EJP65810.1 - 2.8e-46 157.8 4.3 3.8e-46 157.3 4.3 1.2 1 0 0 1 1 1 1 Cation efflux family Fungal_trans PF04082.18 EJP65812.1 - 1.2e-19 70.4 0.4 2.3e-19 69.5 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65812.1 - 2.5e-06 27.5 9.0 3.1e-05 24.0 1.8 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Helicase_IV_N PF12462.8 EJP65812.1 - 0.045 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal ThiF PF00899.21 EJP65812.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 ThiF family zf-C4pol PF14260.6 EJP65812.1 - 0.56 10.7 3.6 1.2 9.7 0.8 2.2 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta PP2C PF00481.21 EJP65813.1 - 7.1e-26 91.4 0.0 1.3e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EJP65813.1 - 0.0077 16.2 0.1 2.3 8.1 0.0 3.6 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) EBP PF05241.12 EJP65814.1 - 1.1e-52 178.1 3.6 1.5e-52 177.6 3.6 1.2 1 0 0 1 1 1 1 Emopamil binding protein TetR_C_33 PF13305.6 EJP65814.1 - 0.032 15.0 0.0 0.061 14.1 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4018 PF13210.6 EJP65814.1 - 0.067 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Voltage_CLC PF00654.20 EJP65815.1 - 1.4e-86 290.9 21.5 1.4e-86 290.9 21.5 2.2 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EJP65815.1 - 3.9e-08 33.6 0.2 4e-06 27.2 0.0 2.9 3 0 0 3 3 3 1 CBS domain DUF1804 PF08822.11 EJP65815.1 - 0.00053 20.0 0.1 0.38 10.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1804) DUF4381 PF14316.6 EJP65815.1 - 0.044 14.0 7.2 3.3 7.9 3.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PMSR PF01625.21 EJP65816.1 - 1.9e-58 197.0 0.1 2.2e-58 196.8 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.20 EJP65817.1 - 6.3e-32 111.1 11.1 8.9e-32 110.6 11.1 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF1686 PF07937.11 EJP65817.1 - 0.5 10.2 2.8 7.5 6.4 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1686) SET PF00856.28 EJP65818.1 - 7.1e-09 36.3 0.0 1.1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 SET domain Antigen_Bd37 PF11641.8 EJP65818.1 - 0.082 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Ank_2 PF12796.7 EJP65819.1 - 1.4e-34 118.5 6.1 3e-15 56.5 0.4 4.5 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP65819.1 - 7.4e-34 115.7 10.3 2.4e-09 37.5 0.1 6.6 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP65819.1 - 3.6e-31 106.8 21.0 1.1e-12 47.9 0.7 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EJP65819.1 - 1.8e-27 94.5 11.4 2e-05 24.8 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EJP65819.1 - 1.2e-25 86.7 5.2 0.00064 20.0 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat cNMP_binding PF00027.29 EJP65820.1 - 5.9e-32 109.6 0.0 2.5e-17 62.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 EJP65820.1 - 3.7e-29 102.2 13.9 1e-28 100.8 13.9 1.8 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 EJP65820.1 - 5e-10 38.6 1.3 0.53 10.5 0.0 7.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 EJP65820.1 - 2.9e-07 30.7 0.0 0.16 12.4 0.0 5.2 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EJP65820.1 - 0.00083 19.2 6.0 0.00094 19.0 0.1 3.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EJP65820.1 - 0.0018 18.2 3.4 0.0048 16.8 0.5 2.8 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 EJP65820.1 - 0.0079 16.6 6.2 33 5.6 0.0 6.8 8 0 0 8 8 8 0 Leucine Rich Repeat PALP PF00291.25 EJP65821.1 - 1.1e-76 258.1 1.2 1.6e-76 257.5 1.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EJP65821.1 - 1.5e-36 124.0 0.0 4.7e-19 68.0 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HU-HIG PF18291.1 EJP65821.1 - 0.23 11.6 0.0 0.65 10.1 0.0 1.8 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Peptidase_S49_N PF08496.10 EJP65822.1 - 0.18 11.9 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Glyco_hydro_76 PF03663.14 EJP65823.1 - 8.5e-20 71.6 3.8 8.5e-20 71.6 3.8 2.8 2 2 0 2 2 2 1 Glycosyl hydrolase family 76 Cep57_CLD_2 PF14197.6 EJP65824.1 - 4.9e-23 81.0 75.6 2.8e-12 46.6 5.1 5.2 3 1 2 5 5 5 3 Centrosome localisation domain of PPC89 HALZ PF02183.18 EJP65824.1 - 0.0021 18.2 3.0 0.0021 18.2 3.0 9.0 6 2 2 8 8 8 3 Homeobox associated leucine zipper KASH_CCD PF14662.6 EJP65824.1 - 0.0098 15.7 19.2 0.0098 15.7 19.2 4.2 2 1 2 4 4 4 2 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 EJP65824.1 - 2.1 8.4 63.0 0.51 10.3 16.5 4.3 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Noc2 PF03715.13 EJP65825.1 - 3e-125 417.4 0.0 5.4e-125 416.6 0.0 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 EJP65825.1 - 6.2e-06 24.8 0.1 6.2e-06 24.8 0.1 3.3 2 1 1 3 3 3 1 Nop14-like family VPS28 PF03997.12 EJP65826.1 - 3.8e-68 228.9 0.4 4.4e-68 228.7 0.4 1.0 1 0 0 1 1 1 1 VPS28 protein PIP5K PF01504.18 EJP65827.1 - 8.4e-33 113.8 0.0 3.7e-24 85.4 0.1 2.9 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EJP65827.1 - 4.5e-27 94.8 0.0 7.5e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EJP65827.1 - 5.1e-15 55.4 10.6 1.5e-14 53.9 10.6 1.9 1 0 0 1 1 1 1 FYVE zinc finger MMM1 PF10296.9 EJP65827.1 - 0.00015 21.0 0.0 0.00038 19.6 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 BolA PF01722.18 EJP65829.1 - 7e-30 103.1 0.9 8.9e-30 102.8 0.9 1.1 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L26 PF16906.5 EJP65829.1 - 0.013 15.9 0.8 0.13 12.7 0.1 2.1 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Lyase_1 PF00206.20 EJP65830.1 - 1e-85 287.9 0.0 1.5e-85 287.4 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EJP65830.1 - 9.6e-23 80.7 0.1 1.9e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SPO22 PF08631.10 EJP65830.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like AMP-binding PF00501.28 EJP65831.1 - 8.8e-70 235.4 0.1 2.1e-69 234.2 0.1 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP65831.1 - 2.2e-14 54.2 0.2 8.9e-14 52.2 0.2 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.18 EJP65832.1 - 2.4e-55 186.7 0.2 3.3e-55 186.2 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Metallophos PF00149.28 EJP65834.1 - 2.7e-09 37.8 5.5 1.4e-08 35.5 5.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase F-box_5 PF18511.1 EJP65834.1 - 0.12 12.0 1.4 9.2 5.9 0.0 3.1 3 0 0 3 3 3 0 F-box DUF993 PF06187.11 EJP65834.1 - 0.18 10.7 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF993) ANAPC_CDC26 PF10471.9 EJP65835.1 - 4e-13 50.0 3.4 8.7e-13 48.9 3.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Rotamase_2 PF13145.6 EJP65835.1 - 0.073 13.9 5.1 0.087 13.7 5.1 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Menin PF05053.13 EJP65835.1 - 0.16 10.3 1.9 0.17 10.2 1.9 1.1 1 0 0 1 1 1 0 Menin Cwf_Cwc_15 PF04889.12 EJP65836.1 - 0.018 14.8 10.3 0.38 10.5 0.6 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 EJP65836.1 - 0.24 11.1 10.4 2.6 7.7 4.0 2.8 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.12 EJP65836.1 - 0.48 9.7 10.3 1.7 7.9 1.8 2.3 2 0 0 2 2 2 0 NOA36 protein Gpr1_Fun34_YaaH PF01184.19 EJP65837.1 - 8.9e-35 120.2 23.9 1.1e-34 119.8 23.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Rad1 PF02144.16 EJP65838.1 - 3.3e-71 239.6 0.0 3.9e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 EJP65838.1 - 2e-15 56.8 11.6 4.2e-15 55.8 11.6 1.6 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Bromodomain PF00439.25 EJP65839.1 - 9.7e-23 80.1 0.2 2.1e-22 79.0 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EJP65839.1 - 6.7e-07 29.6 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP65839.1 - 1.4e-05 25.0 0.2 2.8e-05 24.0 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP65839.1 - 0.0003 21.2 0.6 0.00063 20.1 0.2 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Cwf_Cwc_15 PF04889.12 EJP65840.1 - 0.053 13.3 2.0 0.072 12.8 2.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1656 PF07869.12 EJP65840.1 - 0.24 11.4 2.9 0.43 10.6 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) PQ-loop PF04193.14 EJP65842.1 - 3.7e-22 77.9 4.7 2.4e-13 49.6 0.7 2.5 2 0 0 2 2 2 2 PQ loop repeat AA_permease_N PF08403.10 EJP65843.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal Ank_2 PF12796.7 EJP65844.1 - 7.5e-14 52.1 0.0 2e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EJP65844.1 - 7.7e-12 45.1 0.7 3.4e-06 27.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EJP65844.1 - 1.1e-11 44.8 0.2 2.9e-07 30.6 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EJP65844.1 - 4.7e-09 36.6 0.1 1.8e-07 31.6 0.0 3.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP65844.1 - 2.3e-07 30.6 0.0 0.023 15.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat DapB_N PF01113.20 EJP65845.1 - 0.0074 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EJP65845.1 - 0.01 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EJP65845.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP65845.1 - 0.021 14.7 0.0 0.057 13.3 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding KR PF08659.10 EJP65845.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 EJP65845.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EJP65845.1 - 0.22 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain zf-RING_2 PF13639.6 EJP65846.1 - 5.8e-08 33.0 7.1 5.8e-08 33.0 7.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EJP65846.1 - 0.0025 18.0 8.6 0.0025 18.0 8.6 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 EJP65846.1 - 0.006 16.5 2.6 0.006 16.5 2.6 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 EJP65846.1 - 0.011 15.7 5.3 0.011 15.7 5.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EJP65846.1 - 0.037 13.9 3.4 0.037 13.9 3.4 2.2 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EJP65846.1 - 0.17 12.1 11.4 0.073 13.3 7.8 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-UDP PF14569.6 EJP65846.1 - 0.27 11.4 3.4 0.54 10.4 3.4 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 EJP65846.1 - 2.1 8.3 8.4 21 5.1 8.4 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP65846.1 - 8.5 6.3 12.4 0.17 11.7 5.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NAPRTase PF04095.16 EJP65847.1 - 6.8e-56 189.6 0.1 1e-29 103.8 0.1 2.1 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EJP65847.1 - 3.5e-35 121.1 0.3 9.7e-35 119.7 0.1 1.9 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Rad4 PF03835.15 EJP65848.1 - 1.9e-15 56.8 4.1 3.7e-15 55.9 4.1 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EJP65848.1 - 5.7e-12 46.1 2.8 1.2e-11 45.1 2.8 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pkinase PF00069.25 EJP65849.1 - 7e-18 64.9 0.0 9.2e-08 31.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 EJP65850.1 - 2.4e-09 37.6 16.8 0.12 13.3 0.0 9.4 11 0 0 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP65850.1 - 2e-08 34.4 0.7 0.14 12.5 0.0 6.7 3 2 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EJP65850.1 - 0.0084 16.0 0.1 3.3 7.7 0.0 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 EJP65850.1 - 0.03 14.3 0.3 8.8 6.4 0.1 3.9 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region WSC PF01822.19 EJP65851.1 - 3.7e-18 65.5 6.1 3.7e-18 65.5 6.1 2.1 2 0 0 2 2 2 1 WSC domain Gamma-thionin PF00304.20 EJP65851.1 - 7.8 6.9 9.3 0.27 11.6 2.1 2.3 2 0 0 2 2 2 0 Gamma-thionin family Gpr1_Fun34_YaaH PF01184.19 EJP65852.1 - 1.2e-89 299.4 19.1 1.4e-89 299.2 19.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SSP160 PF06933.11 EJP65853.1 - 0.096 10.9 14.7 0.11 10.6 14.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMEM154 PF15102.6 EJP65853.1 - 7.8 6.4 11.6 13 5.7 11.6 1.3 1 0 0 1 1 1 0 TMEM154 protein family Mucin PF01456.17 EJP65853.1 - 8 6.4 23.8 12 5.8 23.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Podoplanin PF05808.11 EJP65854.1 - 0.015 15.4 0.7 0.032 14.3 0.3 1.7 1 1 0 1 1 1 0 Podoplanin Trp_oprn_chp PF09534.10 EJP65854.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NIBRIN_BRCT_II PF16508.5 EJP65855.1 - 1.9e-39 134.7 0.0 4.4e-39 133.5 0.0 1.7 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 EJP65855.1 - 1.7e-09 37.9 0.0 3.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 EJP65855.1 - 0.067 13.1 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain PI3K_1B_p101 PF10486.9 EJP65855.1 - 1.1 6.9 4.5 1.7 6.3 4.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CENP-B_dimeris PF09026.10 EJP65855.1 - 7.4 7.0 12.3 0.34 11.3 5.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cyt-b5 PF00173.28 EJP65856.1 - 1.1e-14 54.3 0.0 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AMP-binding PF00501.28 EJP65857.1 - 7.6e-67 225.7 0.0 1.3e-66 224.9 0.0 1.3 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP65857.1 - 1.3e-08 35.7 0.0 2.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ELO PF01151.18 EJP65858.1 - 5.8e-71 238.9 1.9 6.8e-71 238.7 1.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Abhydrolase_6 PF12697.7 EJP65859.1 - 1.1e-05 26.2 3.7 1.5e-05 25.7 3.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EJP65859.1 - 0.0015 18.3 0.2 0.0033 17.2 0.1 1.5 2 0 0 2 2 2 1 PGAP1-like protein Lipase_2 PF01674.18 EJP65859.1 - 0.0075 15.8 0.0 0.026 14.0 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 EJP65859.1 - 0.1 12.2 0.6 0.26 10.9 0.6 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FA_hydroxylase PF04116.13 EJP65860.1 - 1e-17 64.7 9.6 1e-17 64.7 9.6 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily ABC2_membrane PF01061.24 EJP65861.1 - 4.2e-28 98.2 23.9 5.9e-28 97.7 23.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EJP65861.1 - 6.3e-25 88.3 0.1 1.1e-24 87.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EJP65861.1 - 7.2e-06 26.0 0.1 0.012 15.5 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EJP65861.1 - 1.4e-05 25.5 0.5 2.9e-05 24.5 0.1 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP65861.1 - 0.00025 21.3 0.1 0.00058 20.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP65861.1 - 0.0011 19.5 0.0 0.0027 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EJP65861.1 - 0.0017 18.8 0.1 0.012 16.0 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EJP65861.1 - 0.0032 17.6 0.0 0.0065 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EJP65861.1 - 0.007 16.1 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EJP65861.1 - 0.0087 16.3 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EJP65861.1 - 0.01 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EJP65861.1 - 0.011 15.5 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 EJP65861.1 - 0.012 14.7 21.0 0.019 14.1 21.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein cobW PF02492.19 EJP65861.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EJP65861.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 EJP65861.1 - 0.042 13.8 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EJP65861.1 - 0.044 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EJP65861.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EJP65861.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 EJP65861.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 EJP65861.1 - 0.13 12.0 0.1 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_25 PF13481.6 EJP65861.1 - 0.13 11.8 0.1 0.33 10.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EJP65861.1 - 0.18 12.1 0.4 0.46 10.8 0.2 1.9 2 1 0 2 2 2 0 AAA domain DUF5317 PF17248.2 EJP65861.1 - 0.88 9.6 8.7 1.8 8.5 8.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5317) Trypsin PF00089.26 EJP65863.1 - 3.4e-31 108.8 0.2 4.6e-31 108.3 0.2 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP65863.1 - 2.7e-05 25.1 0.1 0.00044 21.2 0.1 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF4329 PF14220.6 EJP65863.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) FUSC_2 PF13515.6 EJP65864.1 - 2.2e-25 89.2 7.3 2.2e-25 89.2 7.3 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 EJP65864.1 - 0.003 16.5 5.2 0.003 16.5 5.2 4.2 5 1 1 6 6 6 1 Aluminium activated malate transporter Phage_holin_Dp1 PF16938.5 EJP65864.1 - 0.096 12.9 0.2 0.096 12.9 0.2 2.7 3 0 0 3 3 3 0 Putative phage holin Dp-1 Peptidase_M1_N PF17900.1 EJP65866.1 - 3.5e-05 24.1 0.0 0.046 13.9 0.0 2.9 3 0 0 3 3 3 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EJP65866.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M1 domain Ribosomal_S21 PF01165.20 EJP65866.1 - 0.11 12.3 0.4 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S21 Vps4_C PF09336.10 EJP65866.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain SAS4 PF15460.6 EJP65867.1 - 1.5e-30 105.2 1.9 1.8e-30 105.0 0.1 2.2 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 IQ PF00612.27 EJP65867.1 - 0.0028 17.3 0.1 0.0028 17.3 0.1 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif BSP_II PF05432.11 EJP65867.1 - 0.2 11.3 8.7 0.42 10.3 8.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3340 PF11818.8 EJP65867.1 - 9.6 6.4 17.1 0.23 11.6 7.4 3.1 3 0 0 3 3 3 0 C-terminal domain of tail specific protease (DUF3340) PX PF00787.24 EJP65868.1 - 2.4e-14 53.3 0.0 3.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 PX domain CDP-OH_P_transf PF01066.21 EJP65871.1 - 1.2e-16 61.2 0.3 1.2e-16 61.2 0.3 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Peptidase_M28 PF04389.17 EJP65872.1 - 8.8e-35 120.2 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Ribophorin_II PF05817.14 EJP65873.1 - 3.9e-35 121.5 0.0 4.6e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PhoLip_ATPase_C PF16212.5 EJP65873.1 - 0.0004 20.2 0.1 0.00054 19.8 0.1 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Promethin PF16015.5 EJP65873.1 - 4.3 7.3 8.9 0.8 9.7 2.3 2.4 2 0 0 2 2 2 0 Promethin Abhydrolase_1 PF00561.20 EJP65874.1 - 4.1e-18 65.9 0.0 1.6e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP65874.1 - 1.3e-10 41.0 0.0 3.1e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP65874.1 - 3e-10 41.1 7.2 6.2e-09 36.8 7.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.9 EJP65874.1 - 0.0033 16.6 0.1 0.01 15.0 0.1 1.6 2 0 0 2 2 2 1 Abhydrolase domain containing 18 Thioesterase PF00975.20 EJP65874.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Esterase_phd PF10503.9 EJP65874.1 - 0.012 15.1 0.2 0.52 9.8 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EJP65874.1 - 0.013 15.0 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EJP65874.1 - 0.024 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 EJP65874.1 - 0.072 12.7 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative esterase NMT_C PF02799.15 EJP65875.1 - 6.2e-81 270.9 0.0 1e-80 270.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EJP65875.1 - 5.6e-73 244.1 0.1 4.2e-72 241.2 0.0 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EJP65875.1 - 0.00037 20.6 0.0 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Cut8 PF08559.10 EJP65875.1 - 0.0027 17.3 0.4 0.0044 16.7 0.4 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Acetyltransf_1 PF00583.25 EJP65875.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family H2O2_YaaD PF03883.14 EJP65875.1 - 0.48 9.9 2.0 1.3 8.4 2.0 1.9 1 1 0 1 1 1 0 Peroxide stress protein YaaA Abhydrolase_6 PF12697.7 EJP65876.1 - 2.5e-13 51.1 0.5 4.5e-13 50.3 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP65876.1 - 2.7e-10 39.9 0.5 1.5e-09 37.5 0.2 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP65876.1 - 7.7e-08 32.3 0.1 1.5e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EJP65876.1 - 6.6e-05 22.9 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EJP65876.1 - 0.00016 21.2 0.4 0.0006 19.3 0.3 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EJP65876.1 - 0.0027 17.3 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 EJP65876.1 - 0.0074 16.4 0.1 0.023 14.8 0.1 1.7 2 0 0 2 2 2 1 Thioesterase domain UPF0227 PF05728.12 EJP65876.1 - 0.032 14.2 0.1 0.85 9.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 EJP65876.1 - 0.069 12.9 0.1 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 EJP65876.1 - 0.069 11.8 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) F-box-like PF12937.7 EJP65878.1 - 7.2e-05 22.6 0.1 0.00016 21.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 EJP65878.1 - 0.026 14.8 0.1 0.043 14.1 0.1 1.3 1 0 0 1 1 1 0 PRANC domain Fungal_trans PF04082.18 EJP65879.1 - 1e-24 87.0 0.0 1.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65879.1 - 2.2e-07 30.9 8.8 4.2e-07 30.0 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 EJP65880.1 - 2.7e-45 154.8 0.0 2e-28 99.1 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP65880.1 - 1.4e-12 47.5 0.1 4.6e-10 39.3 0.2 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP65880.1 - 3.7e-10 39.5 0.0 1.5e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP65880.1 - 2.1e-05 24.3 0.4 0.54 9.8 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EJP65880.1 - 2.8e-05 23.4 0.3 0.00064 19.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EJP65880.1 - 0.00044 20.3 2.1 0.17 11.9 2.5 3.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EJP65880.1 - 0.0015 17.8 0.1 0.16 11.2 0.1 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 EJP65880.1 - 0.0075 16.5 0.0 0.026 14.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 EJP65881.1 - 1.2e-22 80.4 26.2 1.9e-22 79.7 26.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TLD PF07534.16 EJP65883.1 - 5.3e-29 101.2 0.1 9.8e-29 100.4 0.1 1.5 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 EJP65883.1 - 1.4e-08 35.6 1.3 3.5e-08 34.3 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function HIG_1_N PF04588.13 EJP65884.1 - 4e-24 84.6 0.6 8.2e-24 83.6 0.6 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4274 PF14096.6 EJP65884.1 - 0.16 12.0 0.5 9.4 6.3 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4274) O-ag_pol_Wzy PF14296.6 EJP65884.1 - 0.2 10.2 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy ZZ PF00569.17 EJP65885.1 - 8.4e-10 38.3 7.5 1.5e-09 37.5 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 EJP65885.1 - 1.3e-09 36.9 7.0 0.00021 20.6 0.2 3.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EJP65885.1 - 4.8e-08 33.3 1.5 0.00038 20.8 0.1 4.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EJP65885.1 - 3.3e-06 26.6 5.8 0.0016 18.2 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EJP65885.1 - 0.0043 16.9 2.4 0.0043 16.9 2.4 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.7 EJP65885.1 - 0.044 13.7 0.1 0.18 11.8 0.0 2.0 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF1363 PF07101.11 EJP65885.1 - 0.046 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) Dockerin_1 PF00404.18 EJP65885.1 - 0.12 12.6 0.0 0.46 10.7 0.0 2.0 1 0 0 1 1 1 0 Dockerin type I domain C1_2 PF03107.16 EJP65885.1 - 0.14 12.5 10.7 0.25 11.7 10.7 1.4 1 0 0 1 1 1 0 C1 domain Ribosomal_60s PF00428.19 EJP65885.1 - 0.51 11.0 8.3 0.21 12.2 3.5 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein EF-hand_5 PF13202.6 EJP65885.1 - 7.6 6.2 6.8 1.2 8.7 0.3 3.0 3 0 0 3 3 3 0 EF hand VIT1 PF01988.19 EJP65886.1 - 4e-66 222.9 1.5 4.6e-66 222.8 1.5 1.0 1 0 0 1 1 1 1 VIT family DUF308 PF03729.13 EJP65886.1 - 1.5 9.2 14.4 0.47 10.8 3.0 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Ada_Zn_binding PF02805.16 EJP65887.1 - 3.4e-32 110.2 5.3 5.6e-32 109.6 5.3 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EJP65887.1 - 1.5e-07 31.3 0.1 3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EJP65887.1 - 2.3e-05 24.6 0.3 5.8e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 EJP65887.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain UPF0175 PF03683.13 EJP65887.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_35 PF13693.6 EJP65887.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Abhydrolase_6 PF12697.7 EJP65888.1 - 3.5e-11 44.2 0.0 4.9e-10 40.4 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP65888.1 - 0.011 15.4 0.0 0.045 13.4 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EJP65888.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Translin PF01997.16 EJP65889.1 - 4.2e-64 216.3 0.1 4.9e-64 216.1 0.1 1.0 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.23 EJP65889.1 - 0.042 14.5 1.9 0.08 13.6 1.1 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain TyeA PF09059.10 EJP65889.1 - 0.069 13.3 0.5 0.74 10.0 0.1 2.6 2 0 0 2 2 2 0 TyeA TBCC_N PF16752.5 EJP65889.1 - 0.12 12.8 0.9 0.27 11.7 0.3 1.7 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain NPV_P10 PF05531.12 EJP65889.1 - 0.17 12.4 1.9 0.82 10.2 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.13 EJP65890.1 - 2.3e-64 217.7 8.1 3.4e-64 217.2 8.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EJP65890.1 - 2.4e-14 53.2 0.1 2.4e-14 53.2 0.1 2.1 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EJP65890.1 - 3.2e-05 23.8 22.2 3.2e-05 23.8 22.2 2.5 2 1 0 2 2 2 1 Glycosyltransferase family 87 F-box-like PF12937.7 EJP65891.1 - 0.03 14.2 0.8 0.07 13.0 0.3 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EJP65891.1 - 0.065 13.1 2.3 1.9 8.4 0.1 3.1 3 0 0 3 3 3 0 F-box domain Peptidase_S8 PF00082.22 EJP65892.1 - 6.2e-30 104.5 9.4 1.4e-29 103.3 9.4 1.4 1 1 0 1 1 1 1 Subtilase family SQS_PSY PF00494.19 EJP65893.1 - 1.9e-40 139.0 0.0 3.4e-40 138.2 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase DnaJ-X PF14308.6 EJP65894.1 - 4.9e-78 261.4 0.7 4.9e-78 261.4 0.7 2.9 4 0 0 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 EJP65894.1 - 1.1e-25 89.5 0.8 2.8e-25 88.2 0.8 1.8 1 0 0 1 1 1 1 DnaJ domain Hamartin PF04388.12 EJP65894.1 - 2.1 6.9 7.6 3.3 6.3 7.6 1.3 1 0 0 1 1 1 0 Hamartin protein GGACT PF06094.12 EJP65895.1 - 1.8e-10 41.5 0.0 2.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EJP65895.1 - 5.4e-05 23.5 0.1 0.00023 21.5 0.0 1.9 2 0 0 2 2 2 1 AIG2-like family Amidoligase_2 PF12224.8 EJP65896.1 - 6.6e-13 48.9 0.0 8.1e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme Acyl_transf_3 PF01757.22 EJP65897.1 - 1.6e-18 66.9 17.6 3e-18 66.0 17.6 1.5 1 1 0 1 1 1 1 Acyltransferase family DUF2142 PF09913.9 EJP65897.1 - 0.0054 15.6 3.6 0.012 14.5 3.6 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) DUF1658 PF07871.11 EJP65897.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1658) APH PF01636.23 EJP65898.1 - 1.4e-06 28.4 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAD PF03068.15 EJP65899.1 - 4.4e-85 286.0 0.0 5.6e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Hexapep PF00132.24 EJP65900.1 - 1.4e-28 97.5 25.1 2e-10 39.9 1.9 6.0 4 1 1 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.6 EJP65900.1 - 5.2e-11 42.9 0.0 7.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.6 EJP65900.1 - 6.8e-09 35.3 23.8 2e-06 27.4 1.2 5.2 3 2 2 5 5 5 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EJP65900.1 - 0.13 11.2 2.0 0.88 8.4 0.5 2.3 1 1 1 2 2 2 0 L-fucokinase DegT_DnrJ_EryC1 PF01041.17 EJP65901.1 - 8.4e-89 298.4 0.0 1.1e-88 298.0 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.22 EJP65901.1 - 1.7e-23 83.7 0.0 2.9e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Beta_elim_lyase PF01212.21 EJP65901.1 - 9.6e-05 21.8 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase 2-Hacid_dh_C PF02826.19 EJP65901.1 - 0.0012 18.3 0.1 0.0027 17.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EJP65901.1 - 0.0031 17.7 0.1 0.0071 16.5 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OKR_DC_1 PF01276.20 EJP65901.1 - 0.0079 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 EJP65901.1 - 0.069 11.7 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Sin3a_C PF16879.5 EJP65902.1 - 1.3e-75 254.8 0.7 4e-75 253.2 0.1 2.2 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 EJP65902.1 - 8.1e-42 141.1 7.0 9.2e-18 64.1 0.0 4.4 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EJP65902.1 - 4.6e-39 132.5 0.0 1.4e-38 130.9 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor PhageMin_Tail PF10145.9 EJP65902.1 - 0.073 12.9 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Phage-related minor tail protein Thiolase_N PF00108.23 EJP65903.1 - 4.1e-91 305.0 0.6 6.3e-72 242.1 0.4 2.3 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 EJP65903.1 - 3e-45 152.9 0.4 2.1e-44 150.1 0.2 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EJP65903.1 - 8.1e-09 35.4 1.1 2.2e-08 34.0 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Peptidase_S32 PF05579.13 EJP65903.1 - 0.025 13.8 0.1 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 ACP_syn_III PF08545.10 EJP65903.1 - 0.43 10.5 2.2 18 5.3 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 EJP65904.1 - 2.2e-43 148.1 0.0 3.5e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EJP65904.1 - 1.4e-34 119.3 7.8 3.3e-34 118.1 7.8 1.7 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EJP65904.1 - 1.2e-24 86.4 0.0 3.4e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EJP65904.1 - 6.1e-18 64.6 0.0 1.6e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EJP65904.1 - 3.9e-09 36.8 0.1 8.8e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EJP65904.1 - 2.9e-08 33.7 0.1 1.4e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II FeS_assembly_P PF01883.19 EJP65905.1 - 3.1e-08 33.7 0.2 0.013 15.7 0.0 2.5 2 0 0 2 2 2 2 Iron-sulfur cluster assembly protein Pheromone PF08015.11 EJP65905.1 - 0.13 13.4 0.2 0.57 11.3 0.0 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone Fungal_trans PF04082.18 EJP65906.1 - 9.9e-12 44.4 0.0 1.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65906.1 - 1.2e-06 28.6 9.8 2.8e-06 27.3 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4199 PF13858.6 EJP65906.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Flp_C PF05202.12 EJP65907.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Recombinase Flp protein Thioredoxin_4 PF13462.6 EJP65908.1 - 0.0022 18.1 0.0 0.0035 17.5 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EJP65908.1 - 0.27 11.0 0.8 2.5 7.8 0.1 2.4 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Zip PF02535.22 EJP65909.1 - 3.2e-49 167.9 3.7 4.6e-49 167.4 3.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter 2OG-FeII_Oxy PF03171.20 EJP65910.1 - 0.0063 17.0 0.1 0.025 15.1 0.1 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.12 EJP65911.1 - 1.4e-50 171.7 0.6 1.4e-50 171.7 0.6 1.5 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 EJP65911.1 - 0.0057 16.9 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Fascin domain bZIP_Maf PF03131.17 EJP65911.1 - 0.047 14.2 0.8 0.047 14.2 0.8 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Frataxin_Cyay PF01491.16 EJP65911.1 - 0.08 13.0 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Frataxin-like domain WD40 PF00400.32 EJP65912.1 - 3.2e-08 34.1 4.3 0.36 11.8 0.1 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.6 EJP65912.1 - 0.011 16.2 2.1 0.37 11.3 1.1 3.1 2 1 0 2 2 2 0 PQQ-like domain BAT PF15915.5 EJP65912.1 - 0.78 9.6 6.1 0.46 10.3 0.5 2.4 2 0 0 2 2 2 0 GAF and HTH_10 associated domain NAD_binding_8 PF13450.6 EJP65914.1 - 0.00053 20.2 0.3 0.0021 18.3 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP65914.1 - 0.0076 15.5 0.1 0.091 12.0 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP65914.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EJP65914.1 - 0.047 13.0 0.0 0.3 10.3 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EJP65914.1 - 0.063 13.3 0.0 0.8 9.8 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Mito_carr PF00153.27 EJP65915.1 - 6.3e-62 205.5 7.4 1.7e-20 72.8 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF295 PF03478.18 EJP65915.1 - 0.063 12.9 0.2 4 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF295) F-box-like PF12937.7 EJP65916.1 - 1.9e-10 40.4 0.4 3.7e-10 39.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP65916.1 - 4.3e-05 23.3 0.3 8e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 EJP65916.1 - 0.062 13.4 0.4 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Baculo_PEP_C PF04513.12 EJP65917.1 - 0.17 11.9 0.6 0.44 10.6 0.2 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_cc2 PF10267.9 EJP65917.1 - 4.5 6.3 7.4 2 7.5 0.1 2.9 3 0 0 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein MBOAT PF03062.19 EJP65918.1 - 4.1e-44 151.4 14.7 9e-44 150.2 14.7 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sugar_tr PF00083.24 EJP65919.1 - 2.4e-127 425.6 19.8 2.7e-127 425.4 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP65919.1 - 3.3e-22 78.9 29.3 5.1e-17 61.8 6.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 EJP65919.1 - 1.1 9.6 4.4 1.6 9.0 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) FAD_binding_2 PF00890.24 EJP65920.1 - 3.9e-84 283.2 0.8 5.8e-84 282.6 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EJP65920.1 - 6.3e-21 74.3 0.1 3e-20 72.2 0.0 2.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EJP65920.1 - 4.6e-13 49.5 0.4 7.8e-13 48.7 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EJP65920.1 - 9.4e-10 38.4 0.9 4.5e-09 36.2 0.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP65920.1 - 7.2e-08 32.5 3.3 2.4e-07 30.9 0.8 2.8 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP65920.1 - 4.1e-06 26.2 0.6 4.5e-05 22.8 0.3 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP65920.1 - 1.6e-05 23.8 2.1 0.01 14.6 0.3 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 EJP65920.1 - 1.6e-05 24.3 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP65920.1 - 0.00026 20.4 0.7 0.00048 19.5 0.7 1.3 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EJP65920.1 - 0.00044 19.6 1.6 0.057 12.7 0.8 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EJP65920.1 - 0.0027 16.9 2.5 0.17 11.0 1.5 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EJP65920.1 - 0.032 13.5 0.8 0.29 10.4 0.2 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EJP65920.1 - 0.044 13.1 0.8 0.077 12.3 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EJP65920.1 - 0.4 11.3 1.4 2.1 9.0 0.5 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fasciclin PF02469.22 EJP65921.1 - 0.00043 20.5 0.0 0.00085 19.5 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain zf-B_box PF00643.24 EJP65922.1 - 0.61 10.3 2.8 1.1 9.5 2.8 1.4 1 0 0 1 1 1 0 B-box zinc finger Vfa1 PF08432.10 EJP65922.1 - 3.3 8.0 10.8 0.5 10.7 5.0 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Fungal_trans PF04082.18 EJP65923.1 - 5.9e-08 32.1 0.0 1.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65923.1 - 1.2e-06 28.5 8.7 2e-06 27.8 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3591 PF12157.8 EJP65925.1 - 3.2e-172 573.2 2.0 4.7e-172 572.6 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 EJP65925.1 - 0.0047 16.9 0.7 0.0086 16.1 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EJP65925.1 - 0.25 11.2 1.7 0.54 10.1 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle SRF-TF PF00319.18 EJP65927.1 - 1.7e-22 78.7 0.3 2.5e-22 78.1 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) LMBR1 PF04791.16 EJP65928.1 - 2.1e-21 76.4 15.4 5.1e-19 68.6 12.5 2.7 2 1 0 2 2 2 1 LMBR1-like membrane protein Ank_2 PF12796.7 EJP65929.1 - 4.1e-56 187.5 11.7 6.1e-17 62.0 1.1 5.9 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP65929.1 - 6.6e-52 173.3 17.3 5.3e-13 49.2 0.3 10.2 5 3 5 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP65929.1 - 1.4e-39 129.6 13.0 2.6e-05 24.3 0.0 12.1 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 EJP65929.1 - 5.3e-39 131.0 24.7 2.4e-06 27.7 0.0 11.7 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EJP65929.1 - 1.2e-37 127.5 17.2 8.5e-08 32.3 0.1 8.7 4 2 3 8 8 8 7 Ankyrin repeats (many copies) CorA PF01544.18 EJP65930.1 - 0.0014 18.0 0.6 0.0025 17.2 0.6 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1712 PF08217.11 EJP65931.1 - 1.2e-11 43.8 0.0 1.2e-10 40.6 0.0 2.3 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) DPBB_1 PF03330.18 EJP65932.1 - 0.0063 16.8 0.1 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase 4HBT_3 PF13622.6 EJP65932.1 - 0.94 9.7 5.4 1.5 9.0 5.4 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily Methyltransf_16 PF10294.9 EJP65935.1 - 5.9e-44 149.9 0.0 7.2e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 EJP65935.1 - 0.0042 16.7 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EJP65935.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EJP65935.1 - 0.054 13.3 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EJP65935.1 - 0.076 13.7 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain YhhN PF07947.14 EJP65936.1 - 2.4e-25 89.2 16.8 3.3e-25 88.8 16.8 1.2 1 0 0 1 1 1 1 YhhN family Dpy-30 PF05186.13 EJP65936.1 - 0.092 12.5 0.7 0.34 10.6 0.7 2.0 1 1 0 1 1 1 0 Dpy-30 motif Beta-lactamase PF00144.24 EJP65937.1 - 2.9e-51 174.7 0.0 4e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EJP65937.1 - 2.7e-07 31.0 0.1 5.3e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) BTB PF00651.31 EJP65938.1 - 0.0029 17.8 0.0 0.059 13.6 0.0 2.5 3 0 0 3 3 3 1 BTB/POZ domain Baculo_PEP_C PF04513.12 EJP65939.1 - 0.0084 16.1 0.3 0.012 15.7 0.3 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus COPI_assoc PF08507.10 EJP65939.1 - 0.043 13.9 6.5 0.98 9.5 0.6 2.2 1 1 2 3 3 3 0 COPI associated protein VPS13_C PF16909.5 EJP65939.1 - 0.063 13.0 1.1 0.084 12.7 1.1 1.2 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal DUF4231 PF14015.6 EJP65939.1 - 0.16 12.5 2.2 0.17 12.4 1.7 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF2207 PF09972.9 EJP65939.1 - 0.21 10.3 1.4 0.21 10.3 1.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tmemb_170 PF10190.9 EJP65939.1 - 0.5 10.7 7.0 0.4 11.1 0.2 2.1 1 1 1 2 2 2 0 Putative transmembrane protein 170 He_PIG PF05345.12 EJP65940.1 - 1.1e-10 41.6 9.0 0.01 16.0 0.1 5.6 5 0 0 5 5 5 4 Putative Ig domain TMEM154 PF15102.6 EJP65940.1 - 0.0047 16.8 1.4 0.0078 16.1 0.1 2.0 2 1 0 2 2 2 1 TMEM154 protein family PP2C PF00481.21 EJP65943.1 - 8.7e-82 274.6 0.0 1.6e-81 273.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PPR_3 PF13812.6 EJP65944.1 - 0.0018 18.3 0.0 0.026 14.6 0.0 2.3 2 0 0 2 2 2 1 Pentatricopeptide repeat domain Aminotran_3 PF00202.21 EJP65945.1 - 1.7e-82 277.3 0.3 2.1e-82 277.0 0.3 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PTPS PF01242.19 EJP65945.1 - 0.11 12.5 0.1 0.86 9.6 0.1 2.5 3 0 0 3 3 3 0 6-pyruvoyl tetrahydropterin synthase LicD PF04991.13 EJP65946.1 - 2.8e-19 70.2 0.2 1.4e-11 45.0 0.2 2.4 1 1 1 2 2 2 2 LicD family HATPase_c_3 PF13589.6 EJP65947.1 - 8.7e-17 61.2 0.0 1.7e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EJP65947.1 - 6.6e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 EJP65947.1 - 0.085 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Clathrin PF00637.20 EJP65948.1 - 1.5e-23 83.3 1.4 3.1e-21 75.7 0.7 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 EJP65948.1 - 1.2e-17 63.8 0.4 2.5e-17 62.8 0.4 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EJP65948.1 - 4.1e-07 29.9 5.6 8.8e-07 28.9 5.6 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EJP65948.1 - 2.1e-05 24.2 5.6 4.9e-05 23.1 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EJP65948.1 - 0.0019 18.5 3.9 0.0041 17.4 3.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EJP65948.1 - 0.002 18.1 5.6 0.0041 17.1 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EJP65948.1 - 0.0058 16.9 5.4 0.014 15.7 5.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EJP65948.1 - 0.23 11.5 1.3 0.56 10.3 1.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EJP65948.1 - 0.24 11.3 9.6 0.034 14.0 5.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP65948.1 - 0.4 10.7 5.9 0.31 11.1 3.7 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 EJP65948.1 - 0.97 9.6 3.5 3.4 7.9 1.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING-like PF08746.11 EJP65948.1 - 1.6 9.1 3.9 4.4 7.7 3.9 1.8 1 0 0 1 1 1 0 RING-like domain CTP_transf_like PF01467.26 EJP65949.1 - 0.0063 16.7 0.1 0.62 10.3 0.0 2.8 2 0 0 2 2 2 1 Cytidylyltransferase-like GHMP_kinases_C PF08544.13 EJP65949.1 - 0.04 14.3 0.3 0.098 13.0 0.3 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal MFS_1 PF07690.16 EJP65950.1 - 1.8e-12 46.9 43.7 1.8e-12 46.9 43.7 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Na_Ca_ex PF01699.24 EJP65951.1 - 8.8e-22 77.7 27.4 3.8e-15 56.2 11.2 3.6 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EJP65951.1 - 4e-16 59.5 11.7 4e-16 59.5 11.7 4.3 5 0 0 5 5 5 1 Inner membrane component domain AAA PF00004.29 EJP65952.1 - 3e-43 147.4 0.0 4.8e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP65952.1 - 4.5e-15 55.2 0.0 9.7e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EJP65952.1 - 3.7e-07 30.4 0.0 7.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EJP65952.1 - 4.9e-07 29.8 0.0 1.3e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EJP65952.1 - 6.1e-06 26.7 0.0 0.00011 22.6 0.1 2.5 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EJP65952.1 - 6.3e-06 26.0 2.3 1.6e-05 24.7 2.3 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EJP65952.1 - 6.3e-05 23.3 0.3 0.016 15.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EJP65952.1 - 9.3e-05 22.2 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EJP65952.1 - 0.00061 20.3 0.1 0.015 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EJP65952.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EJP65952.1 - 0.0014 18.8 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EJP65952.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 EJP65952.1 - 0.0058 16.0 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 EJP65952.1 - 0.0072 15.7 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EJP65952.1 - 0.0097 15.8 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EJP65952.1 - 0.011 15.3 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EJP65952.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 EJP65952.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EJP65952.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 EJP65952.1 - 0.019 14.6 0.1 0.071 12.8 0.1 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain PhoH PF02562.16 EJP65952.1 - 0.023 14.1 0.0 0.096 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 EJP65952.1 - 0.026 14.3 0.0 0.11 12.2 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 EJP65952.1 - 0.031 14.0 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EJP65952.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EJP65952.1 - 0.034 14.5 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EJP65952.1 - 0.049 13.1 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EJP65952.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HR1 PF02185.16 EJP65952.1 - 0.11 12.7 1.0 0.26 11.4 1.0 1.6 1 0 0 1 1 1 0 Hr1 repeat Zeta_toxin PF06414.12 EJP65952.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 EJP65952.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EJP65952.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF2072 PF09845.9 EJP65952.1 - 0.15 12.4 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF1989 PF09347.10 EJP65953.1 - 3e-65 218.9 0.0 3.8e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Y_phosphatase PF00102.27 EJP65954.1 - 1.3e-59 201.6 0.0 2.3e-51 174.7 0.0 3.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 EJP65954.1 - 1.9e-09 38.0 0.0 4.3e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 EJP65954.1 - 0.042 13.7 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EJP65954.1 - 0.051 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family NAD_binding_8 PF13450.6 EJP65955.1 - 1e-10 41.6 0.1 3.9e-09 36.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP65955.1 - 5.6e-10 38.9 0.0 7.8e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EJP65955.1 - 2e-09 36.5 0.0 2.4e-07 29.6 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP65955.1 - 3.9e-09 36.2 0.0 2.2e-07 30.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP65955.1 - 5e-08 32.5 0.2 1.8e-05 24.1 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EJP65955.1 - 9.2e-05 22.5 0.0 0.28 11.3 0.0 3.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EJP65955.1 - 0.00041 20.4 2.2 3.8 7.5 0.7 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EJP65955.1 - 0.00072 19.2 0.6 0.28 10.7 0.2 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP65955.1 - 0.0089 15.2 0.3 0.048 12.7 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain ThiF PF00899.21 EJP65955.1 - 0.01 15.2 0.1 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 ThiF family ApbA PF02558.16 EJP65955.1 - 0.016 14.9 0.1 5 6.8 0.0 3.1 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EJP65955.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EJP65955.1 - 0.04 14.4 0.0 0.89 10.0 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding GIDA PF01134.22 EJP65955.1 - 0.05 12.7 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 EJP65955.1 - 0.05 12.8 0.3 5.8 6.1 0.0 3.0 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 EJP65955.1 - 0.11 13.1 0.1 7.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.13 EJP65956.1 - 4.9e-50 170.3 0.1 6.2e-50 170.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EJP65956.1 - 1.5e-06 27.4 0.2 5.7e-06 25.5 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EJP65956.1 - 3.4e-05 22.9 0.0 4.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydro_lipase PF04083.16 EJP65956.1 - 0.00067 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Peptidase_S9 PF00326.21 EJP65956.1 - 0.17 11.4 0.0 0.65 9.4 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Tcp11 PF05794.13 EJP65958.1 - 2.1e-102 343.5 1.4 2.1e-102 343.5 1.4 2.3 2 0 0 2 2 2 1 T-complex protein 11 UPF0242 PF06785.11 EJP65958.1 - 6.9 6.7 9.1 15 5.6 9.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_M1 PF01433.20 EJP65959.1 - 1.8e-80 269.6 1.5 2.9e-80 268.9 1.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EJP65959.1 - 1.3e-77 261.5 0.5 6.3e-77 259.2 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EJP65959.1 - 1.4e-47 162.3 1.6 4.6e-47 160.6 1.6 1.9 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EJP65959.1 - 0.0042 17.1 0.5 0.015 15.3 0.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) Sad1_UNC PF07738.13 EJP65959.1 - 0.0047 16.9 0.0 0.76 9.8 0.0 3.1 3 0 0 3 3 3 1 Sad1 / UNC-like C-terminal DUF45 PF01863.17 EJP65959.1 - 0.067 13.2 1.4 0.91 9.5 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function DUF45 Acetyltransf_10 PF13673.7 EJP65960.1 - 5e-05 23.2 0.0 9.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP65960.1 - 0.00055 20.2 0.0 0.00069 19.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP65960.1 - 0.0065 16.9 0.0 0.011 16.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP65960.1 - 0.026 14.6 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NRBF2 PF08961.10 EJP65961.1 - 0.0019 17.8 4.3 0.0019 17.8 4.3 2.1 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator Rootletin PF15035.6 EJP65961.1 - 4.3 7.3 25.1 4.3 7.3 12.0 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 EJP65961.1 - 4.8 7.7 27.2 0.26 11.7 7.2 3.2 3 1 1 4 4 4 0 Cell division protein ZapB MMR_HSR1 PF01926.23 EJP65962.1 - 0.00056 20.0 0.0 0.00076 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EJP65962.1 - 0.00074 19.0 0.0 0.00084 18.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EJP65962.1 - 0.0039 17.4 0.0 0.036 14.3 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EJP65962.1 - 0.0086 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 EJP65962.1 - 0.014 14.4 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EJP65962.1 - 0.025 14.5 0.0 0.049 13.5 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EJP65962.1 - 0.041 14.3 0.0 0.049 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EJP65962.1 - 0.048 14.2 0.0 0.058 13.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EJP65962.1 - 0.086 13.0 0.1 0.18 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EJP65962.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 EJP65962.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein MCM PF00493.23 EJP65962.1 - 0.094 11.8 0.0 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain AAA_22 PF13401.6 EJP65962.1 - 0.098 12.9 0.0 0.11 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJP65962.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CobU PF02283.16 EJP65962.1 - 0.16 11.5 0.0 0.3 10.7 0.0 1.4 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Ras PF00071.22 EJP65962.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 Ras family Septin PF00735.18 EJP65962.1 - 0.17 11.1 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Septin cobW PF02492.19 EJP65962.1 - 0.19 11.3 0.0 0.52 9.9 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_membrane PF00664.23 EJP65965.1 - 2.4e-89 299.6 44.5 5.5e-47 160.7 15.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP65965.1 - 5.6e-66 221.2 0.0 7e-32 110.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP65965.1 - 4.3e-12 45.9 1.6 0.00026 20.5 0.4 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP65965.1 - 9.6e-08 31.7 0.4 0.0058 16.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP65965.1 - 9.1e-07 28.9 0.1 0.037 13.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EJP65965.1 - 1e-06 29.2 0.2 0.0028 18.1 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EJP65965.1 - 4.6e-06 26.9 0.6 0.27 11.5 0.1 3.7 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EJP65965.1 - 1.1e-05 24.5 3.7 0.019 13.8 0.1 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 EJP65965.1 - 3.7e-05 23.6 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 EJP65965.1 - 0.00049 20.3 1.8 0.69 10.2 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EJP65965.1 - 0.00054 20.5 0.1 0.23 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EJP65965.1 - 0.0012 19.0 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EJP65965.1 - 0.0012 18.7 0.0 1.1 9.0 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EJP65965.1 - 0.0014 18.0 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 EJP65965.1 - 0.0015 18.8 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EJP65965.1 - 0.0032 17.0 0.1 3.3 7.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 EJP65965.1 - 0.0076 16.3 0.1 5.3 7.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 EJP65965.1 - 0.01 15.0 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_30 PF13604.6 EJP65965.1 - 0.013 15.2 5.0 2.9 7.6 0.2 3.9 4 1 0 4 4 4 0 AAA domain AAA_5 PF07728.14 EJP65965.1 - 0.024 14.6 0.0 11 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EJP65965.1 - 0.034 13.8 0.2 8 6.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 EJP65965.1 - 0.038 14.5 0.0 16 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJP65965.1 - 0.056 13.0 0.1 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EJP65965.1 - 0.06 13.8 0.1 25 5.3 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EJP65965.1 - 0.067 13.6 0.0 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 EJP65965.1 - 0.083 12.8 0.1 5.7 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 YaeQ PF07152.12 EJP65965.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 YaeQ protein Fungal_trans PF04082.18 EJP65966.1 - 1.4e-08 34.1 0.0 3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65966.1 - 0.0015 18.6 4.2 0.0039 17.3 4.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 EJP65967.1 - 2.6e-05 24.4 0.8 4e-05 23.8 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJP65967.1 - 0.0035 17.7 0.1 0.0056 17.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1691 PF07950.11 EJP65968.1 - 8.7e-37 126.1 10.4 6.6e-30 104.0 6.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Cathelicidins PF00666.17 EJP65968.1 - 0.19 12.0 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 Cathelicidin APH PF01636.23 EJP65969.1 - 3.6e-12 46.7 0.0 1.9e-11 44.3 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EJP65969.1 - 0.0081 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain MRP-S26 PF14943.6 EJP65969.1 - 0.036 14.0 0.9 0.053 13.4 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 RIO1 PF01163.22 EJP65969.1 - 0.041 13.5 0.0 6.5 6.3 0.0 2.5 2 0 0 2 2 2 0 RIO1 family MFS_1 PF07690.16 EJP65970.1 - 9.4e-29 100.4 27.4 1.6e-28 99.6 27.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_halogenase PF04820.14 EJP65970.1 - 9.1e-12 44.6 0.1 2e-11 43.5 0.1 1.5 1 1 0 1 1 1 1 Tryptophan halogenase Gln-synt_C PF00120.24 EJP65971.1 - 8.5e-48 163.1 0.0 3.7e-47 161.0 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain RPE65 PF03055.15 EJP65972.1 - 9.5e-17 61.3 0.0 6e-16 58.7 0.0 1.8 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein SQS_PSY PF00494.19 EJP65973.1 - 3.9e-61 206.8 2.3 5.4e-61 206.4 2.3 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.24 EJP65974.1 - 7.2e-22 78.3 0.0 1.4e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NACHT PF05729.12 EJP65974.1 - 1.5e-18 67.2 0.0 3.3e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NAD_binding_8 PF13450.6 EJP65974.1 - 1.3e-13 51.0 0.1 5.6e-13 48.9 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP65974.1 - 5.1e-09 36.2 0.1 1.7e-08 34.4 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase PNP_UDP_1 PF01048.20 EJP65974.1 - 2e-08 33.8 0.5 1.9e-07 30.6 0.5 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily Pyr_redox_2 PF07992.14 EJP65974.1 - 1.3e-07 31.1 0.1 1.9e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EJP65974.1 - 4.8e-05 22.9 0.2 0.00037 20.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AAA_16 PF13191.6 EJP65974.1 - 0.00022 21.6 0.0 0.0013 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain FAD_binding_2 PF00890.24 EJP65974.1 - 0.00032 19.9 1.9 0.00032 19.9 1.9 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EJP65974.1 - 0.006 15.3 0.1 0.31 9.7 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein ResIII PF04851.15 EJP65974.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GIDA PF01134.22 EJP65974.1 - 0.015 14.4 1.8 0.056 12.5 1.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A RNA_helicase PF00910.22 EJP65974.1 - 0.018 15.5 0.0 0.051 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EJP65974.1 - 0.028 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MCRA PF06100.11 EJP65974.1 - 0.033 13.0 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 0 MCRA family NB-ARC PF00931.22 EJP65974.1 - 0.085 12.0 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain FAD_binding_3 PF01494.19 EJP65974.1 - 0.11 11.7 0.2 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain AAA PF00004.29 EJP65974.1 - 0.12 12.8 0.1 0.97 9.9 0.0 2.5 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EJP65974.1 - 0.15 12.3 0.0 0.59 10.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EJP65974.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NAD_binding_9 PF13454.6 EJP65974.1 - 0.22 11.5 1.0 1.6 8.7 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EJP65974.1 - 0.3 11.7 2.6 0.5 11.0 0.7 2.4 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EJP65975.1 - 3.6e-12 45.5 0.0 5.8e-10 38.2 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP65975.1 - 1.5e-10 40.8 0.2 5e-10 39.1 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP65975.1 - 5.3e-08 32.4 1.5 3.5e-06 26.4 0.3 4.1 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP65975.1 - 2.3e-07 31.0 0.0 1.5e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EJP65975.1 - 4.7e-06 26.0 0.2 8.4e-05 21.9 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EJP65975.1 - 2.1e-05 23.9 0.0 0.00055 19.2 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 EJP65975.1 - 0.00017 22.1 0.2 2.3 8.8 0.0 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP65975.1 - 0.0023 17.6 0.2 0.015 14.9 0.1 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP65975.1 - 0.027 13.5 0.2 0.087 11.9 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EJP65975.1 - 0.063 12.3 0.1 2.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EJP65975.1 - 0.07 13.1 0.0 2.5 8.1 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EJP65975.1 - 0.15 12.1 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EJP65975.1 - 0.46 9.5 1.8 0.6 9.1 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A p450 PF00067.22 EJP65976.1 - 1.5e-71 241.5 0.0 1.7e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tecti-min-caps PF09300.10 EJP65976.1 - 0.15 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Tectiviridae, minor capsid ICMT PF04140.14 EJP65977.1 - 1e-11 45.1 0.8 1.2e-09 38.4 0.0 2.9 2 1 1 3 3 3 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EJP65977.1 - 3.5e-07 30.6 4.4 2.2e-06 28.0 0.2 2.7 3 0 0 3 3 3 2 Phospholipid methyltransferase Fic PF02661.18 EJP65978.1 - 7.6e-08 33.1 0.0 1.5e-07 32.2 0.0 1.5 2 0 0 2 2 2 1 Fic/DOC family SAMP PF05924.11 EJP65978.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 SAMP Motif DUF676 PF05057.14 EJP65979.1 - 0.0069 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EJP65979.1 - 0.14 12.0 0.1 1.4 8.8 0.0 2.5 2 1 0 2 2 2 0 Lipase (class 3) FA_hydroxylase PF04116.13 EJP65980.1 - 1.1e-21 77.6 12.0 1.1e-21 77.6 12.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily YL1 PF05764.13 EJP65982.1 - 2.2e-72 244.1 33.2 2.2e-72 244.1 33.2 4.4 4 1 1 5 5 5 1 YL1 nuclear protein YL1_C PF08265.11 EJP65982.1 - 2.6e-09 36.7 0.2 4.5e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Sulfate_transp PF00916.20 EJP65983.1 - 1.5e-79 267.5 12.2 2.5e-79 266.8 12.2 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EJP65983.1 - 3e-16 59.1 0.0 5.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EJP65983.1 - 0.00034 20.9 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 STAS domain DUF2905 PF11146.8 EJP65983.1 - 0.15 12.3 7.7 16 5.8 0.0 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2905) DUF3980 PF13140.6 EJP65983.1 - 6.4 7.3 9.9 2.8 8.4 1.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3980) Thiolase_N PF00108.23 EJP65984.1 - 1.1e-67 228.2 0.1 1.6e-67 227.6 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EJP65984.1 - 8.5e-42 141.7 0.4 3.4e-41 139.7 0.1 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EJP65984.1 - 0.00017 21.2 1.0 0.00047 19.8 0.6 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_cc PF11790.8 EJP65985.1 - 4.9e-67 226.0 0.2 5.7e-67 225.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.13 EJP65985.1 - 0.001 18.5 1.0 0.0027 17.2 1.0 1.7 1 0 0 1 1 1 1 Fip1 motif E1-E2_ATPase PF00122.20 EJP65986.1 - 1.5e-34 119.1 19.5 2.1e-29 102.3 0.4 3.5 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EJP65986.1 - 3.2e-31 108.4 1.0 3.2e-31 108.4 1.0 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EJP65986.1 - 6.4e-21 74.3 0.0 1.7e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EJP65986.1 - 1.9e-19 70.8 0.3 3.4e-15 56.9 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EJP65986.1 - 1.2e-12 47.3 0.0 3.1e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP65986.1 - 5.6e-07 29.6 0.3 6.2e-05 22.9 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP65986.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase bZIP_2 PF07716.15 EJP65987.1 - 0.001 19.1 9.3 0.0022 18.0 9.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EJP65987.1 - 0.0033 17.5 9.6 0.0073 16.4 9.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor Methyltransf_25 PF13649.6 EJP65989.1 - 2.8e-10 40.7 0.1 1.1e-09 38.9 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP65989.1 - 2e-08 33.8 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EJP65989.1 - 7.2e-08 33.0 0.1 2.8e-07 31.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP65989.1 - 8.2e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP65989.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF1722 PF08349.11 EJP65989.1 - 0.098 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Fungal_trans PF04082.18 EJP65990.1 - 4.2e-21 75.2 0.2 6.4e-21 74.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP65990.1 - 0.00052 20.1 6.6 0.0012 18.9 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ox_reductase_C PF08635.10 EJP65990.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Transp_cyt_pur PF02133.15 EJP65991.1 - 2.9e-86 290.0 24.5 3.8e-86 289.6 24.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3040 PF11239.8 EJP65991.1 - 0.027 14.7 3.1 2.4 8.5 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) Thi4 PF01946.17 EJP65993.1 - 1.1e-119 397.9 0.3 1.3e-119 397.6 0.3 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EJP65993.1 - 6.9e-06 25.9 1.5 1.1e-05 25.1 1.1 1.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP65993.1 - 8.6e-05 22.7 0.5 0.00023 21.3 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EJP65993.1 - 0.00029 20.0 0.4 0.00067 18.8 0.4 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EJP65993.1 - 0.00076 18.8 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP65993.1 - 0.0016 18.4 0.8 0.0073 16.3 0.1 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EJP65993.1 - 0.0052 15.9 3.5 0.029 13.4 0.6 2.7 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EJP65993.1 - 0.031 13.6 0.1 0.045 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP65993.1 - 0.043 12.5 0.4 0.061 12.0 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EJP65993.1 - 0.047 13.0 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP65993.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TIM PF00121.18 EJP65994.1 - 3.8e-46 157.4 0.0 4.3e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Abhydrolase_6 PF12697.7 EJP65995.1 - 1.7e-07 32.0 0.0 2.2e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP65995.1 - 6e-07 29.0 0.9 1.3e-06 27.9 0.5 1.7 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EJP65995.1 - 7.6e-06 25.6 0.2 0.011 15.2 0.4 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EJP65995.1 - 0.00044 20.0 1.1 0.024 14.3 0.5 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EJP65995.1 - 0.00065 19.6 2.0 0.0051 16.7 0.1 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF3089 PF11288.8 EJP65995.1 - 0.0062 16.1 0.1 0.0099 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Thioesterase PF00975.20 EJP65995.1 - 0.008 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EJP65995.1 - 0.029 14.1 0.1 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EJP65995.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 EJP65995.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Endotoxin_N PF03945.14 EJP65996.1 - 1.5e-19 70.6 0.0 1.5e-17 64.1 0.0 2.2 2 0 0 2 2 2 2 delta endotoxin, N-terminal domain LacAB_rpiB PF02502.18 EJP65998.1 - 3.1e-44 150.3 0.3 3.5e-44 150.2 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 EJP65998.1 - 0.069 13.2 0.2 0.29 11.2 0.1 1.8 1 1 0 2 2 2 0 Glycine-rich SFCGS Dak1 PF02733.17 EJP65999.1 - 3.4e-100 334.9 0.0 5e-100 334.4 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EJP65999.1 - 1.6e-38 132.4 7.5 3.3e-38 131.3 7.5 1.6 1 0 0 1 1 1 1 DAK2 domain Presenilin PF01080.17 EJP66000.1 - 0.51 9.0 2.0 0.54 9.0 2.0 1.1 1 0 0 1 1 1 0 Presenilin Rpn3_C PF08375.11 EJP66000.1 - 0.8 10.2 9.3 0.12 12.8 4.7 1.8 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal Asp PF00026.23 EJP66001.1 - 9.1e-63 212.6 0.1 1.1e-62 212.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP66001.1 - 6.2e-09 36.3 1.1 0.00046 20.5 0.1 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP66001.1 - 0.00087 19.9 0.3 0.24 12.1 0.2 2.7 2 1 0 2 2 2 2 Aspartyl protease Trypan_PARP PF05887.11 EJP66001.1 - 0.39 10.7 29.4 2.5 8.1 29.4 2.1 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 EJP66002.1 - 8.8e-31 107.1 36.2 1.8e-18 66.6 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EJP66002.1 - 2.4e-10 39.6 17.9 5.7e-05 21.8 0.5 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EJP66002.1 - 5.3e-10 38.7 20.6 4.1e-07 29.2 7.9 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 EJP66002.1 - 2.2e-05 23.5 11.2 6.1e-05 22.1 6.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Aminotran_5 PF00266.19 EJP66003.1 - 2e-22 79.7 0.0 3.1e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EJP66003.1 - 1.3e-06 27.8 0.0 1.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3562 PF12085.8 EJP66003.1 - 0.41 10.3 1.4 37 4.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3562) AMP-binding PF00501.28 EJP66004.1 - 4.4e-50 170.5 4.4 1.5e-27 96.3 0.7 4.0 2 1 2 4 4 4 3 AMP-binding enzyme AMP-binding_C PF13193.6 EJP66004.1 - 0.011 16.7 0.0 0.029 15.3 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Cytochrom_B561 PF03188.16 EJP66004.1 - 0.45 10.6 5.9 3.1 7.9 0.6 2.9 2 1 1 3 3 3 0 Eukaryotic cytochrome b561 DUF3995 PF13160.6 EJP66004.1 - 1.2 9.6 9.6 0.079 13.3 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) PhoLip_ATPase_C PF16212.5 EJP66004.1 - 4.3 7.0 7.2 1 9.1 3.1 1.8 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal ECH_1 PF00378.20 EJP66005.1 - 1.5e-47 162.0 0.0 3.3e-23 82.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP66005.1 - 2.1e-23 83.4 0.0 2.1e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase SIR2 PF02146.17 EJP66006.1 - 1.5e-32 113.0 0.0 2.2e-10 40.7 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Pro-kuma_activ PF09286.11 EJP66007.1 - 1.4e-22 80.5 0.1 3.4e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP66007.1 - 1.2e-06 28.1 0.1 8.8e-06 25.2 0.1 2.0 1 1 0 1 1 1 1 Subtilase family AP_endonuc_2 PF01261.24 EJP66008.1 - 0.028 13.9 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Whi5 PF08528.11 EJP66009.1 - 2.5e-11 42.9 0.0 4.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Whi5 like PBP1_TM PF14812.6 EJP66009.1 - 0.15 12.5 0.2 0.15 12.5 0.2 2.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PP2C PF00481.21 EJP66011.1 - 2e-38 132.5 0.0 8.7e-32 110.8 0.0 2.5 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 EJP66011.1 - 0.007 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C Het-C PF07217.11 EJP66012.1 - 1.4e-279 928.4 0.0 1.6e-279 928.2 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PrpF PF04303.13 EJP66012.1 - 0.041 12.8 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 PrpF protein Cyt-b5 PF00173.28 EJP66013.1 - 8.3e-17 61.1 2.0 1.1e-16 60.7 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EJP66013.1 - 4.6e-12 46.4 20.1 4.6e-12 46.4 20.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EJP66013.1 - 0.0036 17.5 0.0 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region DUF5353 PF17304.2 EJP66013.1 - 1.6 8.5 4.7 0.29 10.9 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5353) RRM_1 PF00076.22 EJP66014.1 - 1.1e-44 150.1 0.8 2.5e-20 72.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EJP66014.1 - 3.2e-22 79.4 0.1 1.1e-21 77.7 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 EJP66014.1 - 3.9e-05 23.6 0.0 0.097 12.7 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EJP66014.1 - 0.00018 21.3 0.0 0.22 11.4 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EJP66014.1 - 0.00096 19.2 0.2 0.035 14.2 0.0 2.8 2 1 0 2 2 2 1 RNA binding motif PHM7_cyt PF14703.6 EJP66014.1 - 0.0034 17.6 0.2 0.38 11.0 0.2 3.0 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 EJP66014.1 - 0.019 15.1 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif RRM_8 PF11835.8 EJP66014.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain RRM_5 PF13893.6 EJP66014.1 - 0.13 11.8 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 EJP66015.1 - 1.1 8.5 6.3 2 7.7 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) I_LWEQ PF01608.17 EJP66015.1 - 3.3 7.9 8.0 2.3 8.5 5.9 1.9 2 0 0 2 2 2 0 I/LWEQ domain FliJ PF02050.16 EJP66015.1 - 4 7.7 8.6 0.42 10.9 3.5 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein VWA PF00092.28 EJP66016.1 - 0.004 17.4 0.8 0.14 12.4 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EJP66016.1 - 0.062 14.0 0.1 1.7 9.3 0.1 2.4 1 1 0 1 1 1 0 von Willebrand factor type A domain Aminotran_1_2 PF00155.21 EJP66017.1 - 3.2e-35 122.0 0.0 3.5e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF755 PF05501.11 EJP66018.1 - 6.3 7.1 10.4 0.83 9.9 6.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) bZIP_2 PF07716.15 EJP66019.1 - 3.9e-12 46.1 12.7 6.7e-12 45.3 12.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EJP66019.1 - 0.00015 21.8 10.4 0.00034 20.6 10.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.11 EJP66019.1 - 0.0024 17.7 1.0 0.0044 16.8 1.0 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Phlebovirus_NSM PF07246.11 EJP66019.1 - 0.0074 15.7 3.9 0.0097 15.3 3.9 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M TSC22 PF01166.18 EJP66019.1 - 0.0078 16.5 1.1 0.017 15.4 1.1 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family LCD1 PF09798.9 EJP66019.1 - 0.016 13.8 3.1 0.015 13.9 3.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein XhlA PF10779.9 EJP66019.1 - 0.02 15.1 4.3 0.038 14.2 4.3 1.4 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_Maf PF03131.17 EJP66019.1 - 0.29 11.7 8.8 0.44 11.1 7.7 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.19 EJP66019.1 - 0.46 8.3 5.5 0.56 8.1 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 EJP66019.1 - 1.8 9.2 7.3 1.9 9.1 5.6 1.9 1 1 1 2 2 2 0 Initiation control protein YabA FAD_binding_3 PF01494.19 EJP66020.1 - 5e-13 49.0 0.4 1.1e-11 44.7 0.5 2.5 2 1 0 2 2 2 1 FAD binding domain Peptidase_M35 PF02102.15 EJP66021.1 - 1.9e-27 96.1 6.7 2.8e-22 79.1 2.0 2.0 1 1 1 2 2 2 2 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EJP66021.1 - 4.2e-23 82.5 1.1 5.3e-23 82.2 1.1 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase CENP-N PF05238.13 EJP66022.1 - 2.3e-128 429.0 0.0 2.7e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.21 EJP66023.1 - 1.1e-44 152.8 0.0 6.9e-44 150.1 0.0 1.9 1 1 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EJP66023.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase Ribonuc_red_lgC PF02867.15 EJP66024.1 - 1.5e-193 644.1 0.0 1.9e-193 643.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EJP66024.1 - 6e-24 83.9 0.0 2.4e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EJP66024.1 - 2.1e-16 60.3 0.0 4.5e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain Abhydrolase_3 PF07859.13 EJP66026.1 - 1.3e-07 31.7 0.1 2.4e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Eno-Rase_NADH_b PF12242.8 EJP66026.1 - 0.0025 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_4 PF08386.10 EJP66026.1 - 0.008 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Pirin PF02678.16 EJP66027.1 - 2e-29 101.8 0.0 3.9e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EJP66027.1 - 9.1e-26 90.2 0.0 3.1e-24 85.3 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EJP66027.1 - 5.2e-07 29.3 1.4 0.0002 21.0 0.5 2.7 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EJP66027.1 - 0.046 13.4 0.2 2.2 8.0 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF861) Amidase PF01425.21 EJP66028.1 - 3.3e-71 240.6 0.0 3.8e-64 217.3 0.0 2.2 2 0 0 2 2 2 2 Amidase SelP_N PF04592.14 EJP66028.1 - 4.7 6.6 15.2 6.8 6.0 15.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CTP_transf_1 PF01148.20 EJP66029.1 - 3e-80 269.8 25.3 3.7e-80 269.5 25.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Pro_CA PF00484.19 EJP66030.1 - 5.3e-51 173.0 0.0 7.8e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase DUF3636 PF12331.8 EJP66031.1 - 8e-44 149.1 0.5 1.4e-43 148.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF3584 PF12128.8 EJP66031.1 - 0.34 8.4 5.0 0.49 7.8 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NAD_binding_10 PF13460.6 EJP66032.1 - 0.0013 18.6 0.3 0.0019 18.1 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EJP66032.1 - 0.004 16.7 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EJP66032.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 EJP66032.1 - 0.086 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 EJP66032.1 - 0.09 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EJP66032.1 - 0.15 11.0 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CytochromB561_N PF09786.9 EJP66033.1 - 1.2 8.0 5.8 1.7 7.6 5.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal UDPG_MGDP_dh_N PF03721.14 EJP66035.1 - 1.7e-50 171.2 0.0 3.9e-31 108.1 0.1 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EJP66035.1 - 1.1e-31 108.9 0.0 2.5e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EJP66035.1 - 2.1e-22 79.5 0.0 6.6e-18 65.1 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 EJP66035.1 - 0.0069 16.6 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EJP66035.1 - 0.011 16.0 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EJP66035.1 - 0.081 13.0 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EJP66035.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glycos_transf_1 PF00534.20 EJP66036.1 - 4.8e-37 127.1 0.0 8.2e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EJP66036.1 - 1.1e-29 103.6 0.0 1.8e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EJP66036.1 - 2.1e-14 54.2 0.1 3.9e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EJP66036.1 - 6.6e-11 42.5 0.0 5.7e-10 39.4 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EJP66036.1 - 4.7e-10 39.7 0.0 1.1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF485 PF04341.12 EJP66036.1 - 0.07 13.1 1.1 0.14 12.1 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 FmdA_AmdA PF03069.15 EJP66038.1 - 1.3e-171 570.5 0.0 1.5e-171 570.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Lyase_8 PF02278.18 EJP66039.1 - 1.8e-63 214.4 2.9 2.8e-63 213.8 2.9 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 EJP66039.1 - 1.3e-20 73.6 0.2 2.3e-20 72.8 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 EJP66039.1 - 0.0074 16.7 0.0 0.038 14.5 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain MFS_1 PF07690.16 EJP66040.1 - 5e-38 130.9 22.1 5e-38 130.9 22.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP66040.1 - 3.1e-06 26.3 13.0 7.1e-06 25.1 13.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EJP66040.1 - 0.0001 21.8 1.0 0.0001 21.8 1.0 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PgaD PF13994.6 EJP66040.1 - 0.065 13.3 4.2 1.5 8.8 0.0 3.1 4 0 0 4 4 4 0 PgaD-like protein DUF3357 PF11837.8 EJP66040.1 - 0.15 12.6 0.1 1.5 9.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF4834 PF16118.5 EJP66040.1 - 1 10.4 3.4 2.9 8.9 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) AAA_33 PF13671.6 EJP66041.1 - 3.3e-11 43.5 0.0 4.1e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 EJP66041.1 - 1.8e-10 41.1 0.0 2.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EJP66041.1 - 7.4e-08 33.0 0.0 2.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EJP66041.1 - 1.2e-06 28.5 0.0 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase Cytidylate_kin PF02224.18 EJP66041.1 - 2.9e-06 27.2 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase APS_kinase PF01583.20 EJP66041.1 - 8e-05 22.6 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 EJP66041.1 - 0.0021 18.5 0.0 0.013 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJP66041.1 - 0.0068 16.7 0.0 0.0099 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP66041.1 - 0.0083 16.5 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EJP66041.1 - 0.014 14.6 0.0 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin CobU PF02283.16 EJP66041.1 - 0.015 14.9 0.0 0.1 12.1 0.0 2.0 2 1 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Rad17 PF03215.15 EJP66041.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_15 PF13175.6 EJP66041.1 - 0.022 14.5 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 EJP66041.1 - 0.034 13.8 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase DUF5319 PF17252.2 EJP66041.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5319) KTI12 PF08433.10 EJP66041.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 EJP66041.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EJP66041.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CoaE PF01121.20 EJP66041.1 - 0.12 12.0 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Phage_TAC_8 PF10666.9 EJP66041.1 - 0.18 12.1 0.0 10 6.4 0.0 2.2 2 1 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 SMC_N PF02463.19 EJP66041.1 - 0.21 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain adh_short PF00106.25 EJP66042.1 - 1.8e-42 145.1 0.4 2.7e-42 144.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP66042.1 - 2.4e-33 115.6 0.8 5e-33 114.6 0.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.18 EJP66042.1 - 5.4e-06 25.6 0.0 3.9e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 EJP66042.1 - 0.00086 19.3 0.6 0.0027 17.7 0.6 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP66042.1 - 0.0061 16.1 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EJP66042.1 - 0.035 14.0 0.5 5.4 6.9 0.0 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ERAP1_C PF11838.8 EJP66043.1 - 2.2e-86 290.3 0.0 1.3e-85 287.8 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EJP66043.1 - 7.9e-85 283.8 0.3 1.2e-84 283.3 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EJP66043.1 - 7e-54 182.8 0.6 1.1e-53 182.2 0.6 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ABC2_membrane PF01061.24 EJP66044.1 - 5.7e-87 290.5 70.2 1.2e-44 152.3 26.8 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EJP66044.1 - 4.1e-39 134.2 0.0 4.2e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EJP66044.1 - 1.5e-32 111.4 11.9 4.2e-29 100.3 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EJP66044.1 - 1.3e-14 54.6 0.1 4.3e-14 52.9 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EJP66044.1 - 7.9e-05 22.6 0.1 0.0055 16.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EJP66044.1 - 9.1e-05 22.9 1.1 0.0037 17.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EJP66044.1 - 0.00016 21.4 0.7 0.051 13.3 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EJP66044.1 - 0.00017 21.8 0.1 0.0029 17.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EJP66044.1 - 0.00024 20.8 0.2 0.0047 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EJP66044.1 - 0.00035 19.8 52.9 0.0023 17.1 22.9 3.8 2 2 0 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.19 EJP66044.1 - 0.003 17.0 0.1 0.18 11.2 0.0 3.1 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP66044.1 - 0.004 17.7 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EJP66044.1 - 0.012 15.4 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EJP66044.1 - 0.014 15.0 1.7 0.068 12.7 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EJP66044.1 - 0.015 15.7 0.5 1.1 9.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EJP66044.1 - 0.015 15.0 0.4 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EJP66044.1 - 0.017 15.7 4.4 0.034 14.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 EJP66044.1 - 0.044 14.2 0.2 16 5.9 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EJP66044.1 - 0.05 13.7 0.0 17 5.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EJP66044.1 - 0.11 12.9 0.1 29 5.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EJP66044.1 - 0.14 12.1 2.1 3.1 7.7 0.5 2.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 EJP66044.1 - 0.46 10.8 2.2 1.8 8.9 0.2 2.5 2 1 0 2 2 2 0 AAA domain DUF4834 PF16118.5 EJP66044.1 - 0.82 10.7 5.1 65 4.6 0.0 4.9 5 0 0 5 5 4 0 Domain of unknown function (DUF4834) DUF4134 PF13572.6 EJP66045.1 - 0.06 13.6 0.7 0.15 12.4 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Amidase PF01425.21 EJP66046.1 - 7e-72 242.8 0.4 5.6e-68 229.9 0.0 2.1 2 0 0 2 2 2 2 Amidase Aldedh PF00171.22 EJP66047.1 - 2.5e-146 487.8 0.0 3e-146 487.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 EJP66048.1 - 2.7e-53 181.3 0.0 3.4e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP66048.1 - 6e-39 133.8 0.0 9.5e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EJP66048.1 - 0.00013 21.1 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EJP66048.1 - 0.0004 20.6 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP66048.1 - 0.018 14.2 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP66048.1 - 0.021 14.4 0.0 0.095 12.3 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP66048.1 - 0.044 12.9 0.0 0.7 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 EJP66048.1 - 0.055 12.3 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AMP-binding PF00501.28 EJP66049.1 - 1.5e-227 755.2 0.0 4.7e-81 272.5 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EJP66049.1 - 3.9e-175 582.9 0.0 9.7e-31 106.9 0.0 7.5 6 2 0 7 7 7 7 Condensation domain PP-binding PF00550.25 EJP66049.1 - 2.6e-49 165.4 15.2 3.3e-09 37.0 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP66049.1 - 3.5e-08 34.3 0.0 0.11 13.5 0.0 3.9 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EJP66049.1 - 0.00019 20.3 0.0 0.7 8.5 0.0 4.6 6 0 0 6 6 6 1 Transferase family WES_acyltransf PF03007.16 EJP66049.1 - 0.00068 19.5 0.4 38 3.9 0.1 4.6 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.6 EJP66050.1 - 1.3e-106 356.6 0.0 1.6e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EJP66050.1 - 5.6e-07 29.1 0.1 3.8e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP66050.1 - 1.9e-05 24.0 0.0 0.00049 19.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP66050.1 - 0.00023 21.2 0.0 0.0057 16.7 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Evr1_Alr PF04777.13 EJP66050.1 - 0.076 13.5 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Erv1 / Alr family Fungal_trans PF04082.18 EJP66051.1 - 7.9e-15 54.6 0.0 1.7e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66051.1 - 1.1e-05 25.4 5.8 2.4e-05 24.4 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4689 PF15755.5 EJP66051.1 - 0.00016 21.4 0.1 0.00034 20.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4689) FF PF01846.19 EJP66052.1 - 6.7e-12 45.4 4.6 5.4e-09 36.1 0.1 3.0 3 0 0 3 3 3 2 FF domain WW PF00397.26 EJP66052.1 - 2.2e-09 37.2 5.1 2.2e-09 37.2 5.1 2.2 2 0 0 2 2 2 1 WW domain PAP2 PF01569.21 EJP66053.1 - 2.9e-29 101.6 0.6 2.9e-29 101.6 0.6 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EJP66053.1 - 0.0011 18.7 5.6 0.0035 17.0 2.2 2.6 1 1 1 2 2 2 2 PAP2 superfamily Proteasome PF00227.26 EJP66054.1 - 5e-61 205.5 0.1 6.1e-61 205.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJP66054.1 - 3.7e-13 48.9 0.1 8.7e-13 47.7 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EJP66054.1 - 0.0095 16.0 0.6 0.031 14.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EJP66054.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SPOC PF07744.13 EJP66055.1 - 1.8e-25 89.6 0.0 2.9e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 EJP66055.1 - 3.1e-08 33.4 10.8 3.8e-08 33.1 9.6 1.8 2 0 0 2 2 2 1 PHD-finger Med7 PF05983.11 EJP66056.1 - 6.9e-61 205.7 1.8 8.7e-61 205.3 1.8 1.1 1 0 0 1 1 1 1 MED7 protein CENP-O PF09496.10 EJP66056.1 - 0.063 13.2 2.1 0.069 13.1 0.5 1.8 2 1 0 2 2 2 0 Cenp-O kinetochore centromere component Calici_coat PF00915.20 EJP66056.1 - 1.9 7.3 3.0 3.1 6.6 3.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein OrsD PF12013.8 EJP66057.1 - 0.031 14.7 1.8 0.1 13.1 1.0 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4769 PF15992.5 EJP66057.1 - 5.9 6.6 6.9 12 5.6 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) F-box-like PF12937.7 EJP66058.1 - 3.4e-06 26.9 1.5 3.4e-06 26.9 1.5 2.2 2 0 0 2 2 2 1 F-box-like RPEL PF02755.15 EJP66058.1 - 0.00011 21.8 0.2 0.00027 20.5 0.2 1.7 1 0 0 1 1 1 1 RPEL repeat F-box PF00646.33 EJP66058.1 - 0.0035 17.2 0.7 0.0035 17.2 0.7 3.0 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 EJP66058.1 - 0.086 12.7 0.1 0.29 11.0 0.1 1.9 1 0 0 1 1 1 0 F-box zf-CCHC_2 PF13696.6 EJP66059.1 - 2.8 7.8 5.9 5.7 6.9 0.4 2.7 2 0 0 2 2 2 0 Zinc knuckle LAMTOR PF15454.6 EJP66060.1 - 6.3e-06 26.7 0.1 1.6e-05 25.4 0.1 1.7 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Haem_degrading PF03928.14 EJP66061.1 - 5.9e-29 100.5 0.2 7.2e-29 100.3 0.2 1.1 1 0 0 1 1 1 1 Haem-degrading Dynamin_N PF00350.23 EJP66062.1 - 3.3e-21 76.1 0.0 1.6e-20 73.9 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EJP66062.1 - 5.6e-13 48.7 0.8 2.3e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 EJP66062.1 - 0.0066 16.6 1.4 0.011 15.9 0.1 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EJP66062.1 - 0.01 15.9 0.0 0.72 10.0 0.0 3.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF2406 PF10295.9 EJP66062.1 - 0.11 13.2 0.2 0.56 10.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) DUF445 PF04286.12 EJP66062.1 - 0.38 10.5 2.1 0.83 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Nuc_sug_transp PF04142.15 EJP66063.1 - 2.2e-97 326.0 6.7 3.3e-97 325.4 6.7 1.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EJP66063.1 - 2e-09 37.1 2.0 3.8e-09 36.2 2.0 1.5 1 1 0 1 1 1 1 UAA transporter family DsbB PF02600.16 EJP66063.1 - 0.0017 18.8 0.7 0.0054 17.2 0.7 1.8 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB EamA PF00892.20 EJP66063.1 - 0.0091 16.2 27.9 0.022 14.9 5.5 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EJP66063.1 - 0.069 12.5 12.1 0.79 9.0 0.6 2.6 2 2 0 2 2 2 0 Triose-phosphate Transporter family PGM_PMM_II PF02879.16 EJP66063.1 - 0.081 13.5 0.0 0.37 11.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF1129 PF06570.11 EJP66063.1 - 1 8.8 4.1 0.37 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Hira PF07569.11 EJP66064.1 - 2.5e-84 282.5 0.0 5.9e-84 281.2 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EJP66064.1 - 4.1e-32 109.7 25.0 2.2e-05 25.1 0.0 9.0 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66064.1 - 1.4e-16 60.6 0.0 0.0061 16.8 0.0 6.7 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EJP66064.1 - 3.2e-10 39.6 0.5 7.8e-10 38.4 0.5 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EJP66064.1 - 6.3e-06 26.0 0.1 8.7 6.4 0.0 5.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EJP66064.1 - 0.00046 19.3 0.6 0.25 10.2 0.0 4.3 4 2 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EJP66064.1 - 0.045 11.7 0.0 0.24 9.4 0.0 2.1 3 0 0 3 3 3 0 IKI3 family NACHT_N PF17100.5 EJP66065.1 - 2.6e-33 115.8 0.0 3.5e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Pro_isomerase PF00160.21 EJP66066.1 - 4e-34 118.2 0.1 9.6e-33 113.7 0.1 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GAS PF13851.6 EJP66067.1 - 0.00085 18.7 6.3 0.0033 16.8 0.6 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EJP66067.1 - 0.0042 17.1 4.0 0.007 16.4 4.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 EJP66067.1 - 0.039 14.1 1.9 0.18 12.0 1.9 2.1 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 DivIVA PF05103.13 EJP66067.1 - 0.073 13.2 2.5 0.089 12.9 0.5 2.0 2 0 0 2 2 2 0 DivIVA protein ATG16 PF08614.11 EJP66067.1 - 0.19 11.9 14.8 0.32 11.2 2.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF5315 PF17242.2 EJP66067.1 - 0.29 11.0 0.2 0.29 11.0 0.2 3.1 3 0 0 3 3 3 0 Disordered region of unknown function (DUF5315) YabA PF06156.13 EJP66067.1 - 0.36 11.5 4.4 3.4 8.3 3.7 2.6 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 EJP66067.1 - 0.66 10.5 11.5 6.9 7.2 11.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2353 PF09789.9 EJP66067.1 - 1 8.6 10.3 3 7.1 8.3 1.9 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) CENP-H PF05837.12 EJP66067.1 - 1.7 9.1 7.5 0.95 9.9 3.4 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Ada3 PF10198.9 EJP66067.1 - 2.9 8.1 7.7 1.2 9.3 2.0 2.3 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 UPF0242 PF06785.11 EJP66067.1 - 5.4 7.1 7.3 14 5.8 7.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 EJP66069.1 - 3.3e-41 140.4 42.8 4.2e-38 130.3 26.3 19.5 8 4 10 19 19 19 6 TPR/MLP1/MLP2-like protein LPP PF04728.13 EJP66069.1 - 0.53 10.7 0.0 0.53 10.7 0.0 17.4 21 1 0 21 21 21 0 Lipoprotein leucine-zipper DEAD PF00270.29 EJP66070.1 - 8.4e-40 136.4 0.0 2.4e-39 134.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP66070.1 - 4.1e-26 91.5 0.0 1.6e-25 89.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4598 PF15370.6 EJP66070.1 - 0.34 11.4 0.1 0.34 11.4 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4598) CDC45 PF02724.14 EJP66070.1 - 4.7 5.4 15.2 0.49 8.6 6.2 2.8 3 0 0 3 3 3 0 CDC45-like protein Sigma70_ner PF04546.13 EJP66070.1 - 5.1 6.9 17.7 0.12 12.2 0.8 3.2 3 0 0 3 3 3 0 Sigma-70, non-essential region NARP1 PF12569.8 EJP66070.1 - 6.8 5.5 8.7 16 4.2 8.7 1.6 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DRMBL PF07522.14 EJP66071.1 - 2.5e-05 24.4 0.0 0.0001 22.4 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase DIT1_PvcA PF05141.12 EJP66072.1 - 1.2e-96 323.4 0.0 1.9e-96 322.8 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 EJP66072.1 - 1.3e-23 84.1 0.0 3.9e-23 82.6 0.0 1.9 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.19 EJP66073.1 - 1e-61 209.1 0.0 1.5e-61 208.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EJP66073.1 - 1.6e-05 24.3 0.2 0.00088 18.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP66073.1 - 2.5e-05 24.0 0.8 0.00016 21.4 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP66073.1 - 2.7e-05 23.4 1.5 0.023 13.8 0.5 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EJP66073.1 - 0.00011 21.5 0.5 0.025 13.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EJP66073.1 - 0.00051 19.5 0.6 0.025 13.9 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EJP66073.1 - 0.00071 20.1 0.1 0.066 13.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP66073.1 - 0.00084 18.1 0.7 0.037 12.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EJP66073.1 - 0.0015 18.7 0.6 0.0035 17.6 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EJP66073.1 - 0.0065 15.9 0.1 0.0087 15.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP66073.1 - 0.009 15.1 0.3 0.019 14.0 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EJP66073.1 - 0.013 14.7 0.1 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EJP66073.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 EJP66073.1 - 0.033 14.7 0.0 0.068 13.7 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain PAN_4 PF14295.6 EJP66074.1 - 0.00032 20.5 0.8 0.00062 19.6 0.8 1.5 1 0 0 1 1 1 1 PAN domain DUF2427 PF10348.9 EJP66074.1 - 0.053 13.3 0.2 0.086 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF1610 PF07754.11 EJP66074.1 - 0.097 12.7 0.8 0.26 11.3 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Cyt_c_ox_IV PF12270.8 EJP66074.1 - 0.15 12.2 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV SP_C-Propep PF08999.10 EJP66074.1 - 0.16 11.7 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF4834 PF16118.5 EJP66074.1 - 0.18 12.7 0.0 0.31 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Sigma_reg_N PF13800.6 EJP66074.1 - 0.2 11.9 0.1 0.33 11.3 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Shisa PF13908.6 EJP66074.1 - 1.1 9.5 5.3 0.45 10.7 2.1 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Peptidase_S28 PF05577.12 EJP66075.1 - 7e-48 163.5 0.0 3.7e-47 161.1 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 EJP66075.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) 2-Hacid_dh_C PF02826.19 EJP66076.1 - 8.1e-37 126.3 0.0 5.2e-28 97.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NACHT PF05729.12 EJP66077.1 - 1e-08 35.3 0.0 2.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EJP66077.1 - 7.4e-08 33.0 0.0 7.4e-08 33.0 0.0 3.4 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EJP66077.1 - 1.8e-05 25.0 0.0 6.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EJP66077.1 - 0.016 15.6 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EJP66077.1 - 0.021 15.4 0.0 0.064 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EJP66077.1 - 0.021 15.0 0.2 0.52 10.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EJP66077.1 - 0.027 15.0 0.0 0.077 13.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EJP66077.1 - 0.03 14.1 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3549 PF12069.8 EJP66077.1 - 0.035 13.1 0.0 0.097 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) NTPase_1 PF03266.15 EJP66077.1 - 0.093 12.6 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 EJP66077.1 - 0.13 12.0 0.1 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EJP66077.1 - 0.18 11.9 0.0 0.52 10.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EJP66077.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 EJP66077.1 - 0.23 11.2 0.1 0.4 10.4 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DAO PF01266.24 EJP66079.1 - 1.1e-51 176.4 0.1 1.8e-51 175.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EJP66079.1 - 1.5e-39 134.7 0.0 5.2e-39 133.0 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EJP66079.1 - 6.8e-09 35.3 3.3 0.0011 18.1 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 EJP66079.1 - 7.7e-05 22.2 0.4 0.0006 19.3 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP66079.1 - 0.00074 18.8 0.0 0.002 17.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP66079.1 - 0.019 15.2 0.3 0.19 11.9 0.2 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EJP66079.1 - 0.038 13.2 0.0 0.088 12.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EJP66079.1 - 0.039 13.8 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EJP66079.1 - 0.064 12.3 1.3 0.54 9.3 0.1 2.5 2 1 1 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 EJP66079.1 - 0.092 11.4 0.2 0.15 10.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EJP66079.1 - 0.15 12.7 0.8 0.66 10.6 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MIP PF00230.20 EJP66080.1 - 2.2e-53 181.3 7.6 2.7e-53 181.0 7.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.16 EJP66081.1 - 1.2e-71 240.6 1.1 2.1e-71 239.7 0.7 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EJP66081.1 - 1.3e-66 224.7 0.0 1.8e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain ROK PF00480.20 EJP66081.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 ROK family BcrAD_BadFG PF01869.20 EJP66081.1 - 0.067 12.7 0.2 1 8.8 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Fungal_trans PF04082.18 EJP66082.1 - 1e-18 67.3 0.9 1.4e-18 66.9 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66082.1 - 2.6e-08 33.8 10.2 5.5e-08 32.8 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3021 PF11457.8 EJP66083.1 - 0.098 13.0 0.7 0.55 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) RseC_MucC PF04246.12 EJP66083.1 - 2.3 8.2 6.0 0.73 9.8 0.6 2.6 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Gly_transf_sug PF04488.15 EJP66084.1 - 2.2e-11 44.2 0.1 4.8e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EJP66084.1 - 0.053 12.8 0.1 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF1656 PF07869.12 EJP66084.1 - 0.33 11.0 8.3 0.77 9.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) QCR10 PF09796.9 EJP66084.1 - 0.81 9.8 4.0 2.1 8.5 0.3 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) 2TM PF13239.6 EJP66085.1 - 0.32 11.3 3.9 1.3 9.4 0.3 2.4 2 0 0 2 2 2 0 2TM domain PLA2_B PF01735.18 EJP66086.1 - 2.3e-167 557.4 3.9 2.7e-167 557.1 3.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Acyltransferase PF01553.21 EJP66087.1 - 2e-26 92.2 0.0 3.1e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EJP66087.1 - 3e-12 46.4 0.3 6.4e-12 45.4 0.3 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Hydin_ADK PF17213.3 EJP66088.1 - 0.15 12.3 0.1 0.21 11.8 0.1 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain EVE PF01878.18 EJP66089.1 - 1.3e-46 158.2 0.9 4.3e-46 156.5 0.0 1.9 2 0 0 2 2 2 1 EVE domain RNA_pol_Rbc25 PF08292.12 EJP66089.1 - 0.35 11.1 0.0 0.35 11.1 0.0 2.4 2 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 MFS_1 PF07690.16 EJP66090.1 - 5.6e-35 120.9 50.2 2.8e-30 105.4 33.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP66090.1 - 8.4e-19 67.8 20.9 2.7e-17 62.8 20.9 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter DnaJ PF00226.31 EJP66091.1 - 6.7e-12 45.3 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Glyco_transf_34 PF05637.12 EJP66092.1 - 6e-69 232.4 0.0 7.3e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EJP66092.1 - 0.00064 19.3 0.0 0.0077 15.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF273 RINGv PF12906.7 EJP66093.1 - 7.5e-09 35.6 5.2 5.8e-08 32.7 5.2 2.1 1 1 0 1 1 1 1 RING-variant domain PHD_4 PF16866.5 EJP66093.1 - 0.0027 17.8 4.1 2.3 8.4 0.0 2.3 1 1 1 2 2 2 2 PHD-finger PhnA_Zn_Ribbon PF08274.12 EJP66093.1 - 0.12 12.4 0.3 0.24 11.4 0.3 1.5 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Proteasome PF00227.26 EJP66094.1 - 7.7e-55 185.3 0.1 1.6e-32 112.6 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EJP66094.1 - 1.1e-10 40.9 0.3 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RCC1_2 PF13540.6 EJP66095.1 - 1.3e-10 40.8 0.2 1.1e-05 25.1 0.0 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EJP66095.1 - 3.9e-09 37.0 0.7 0.00026 21.5 0.0 5.5 4 2 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ribonuclease_3 PF00636.26 EJP66096.1 - 2e-39 134.4 0.0 1.4e-18 67.4 0.0 3.5 4 0 0 4 4 4 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EJP66096.1 - 1.4e-24 86.7 0.0 1.3e-10 41.5 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EJP66096.1 - 2.4e-23 82.1 0.1 6.5e-23 80.7 0.1 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 EJP66096.1 - 4.7e-19 68.8 0.0 1.3e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP66096.1 - 4.4e-18 65.7 0.0 8.5e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EJP66096.1 - 1.9e-14 54.1 0.0 5.8e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 EJP66096.1 - 0.028 14.0 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_18 PF13238.6 EJP66097.1 - 2.4e-05 24.9 0.0 0.00022 21.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 EJP66097.1 - 0.00096 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 EJP66097.1 - 0.003 17.8 0.0 0.0067 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EJP66097.1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EJP66097.1 - 0.046 13.4 0.0 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase PRK PF00485.18 EJP66097.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EJP66097.1 - 0.084 13.3 0.0 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EJP66097.1 - 0.088 11.9 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EJP66097.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJP66097.1 - 0.14 12.7 0.0 0.31 11.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter tRNA_lig_kinase PF08303.11 EJP66097.1 - 0.22 11.6 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain Urocanase PF01175.18 EJP66099.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.3 1 1 0 1 1 1 0 Urocanase Rossmann-like domain GPHR_N PF12537.8 EJP66099.1 - 0.035 14.2 0.2 0.29 11.3 0.0 2.3 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal APH PF01636.23 EJP66100.1 - 0.0022 17.9 0.1 0.032 14.2 0.1 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family PTH2 PF01981.16 EJP66101.1 - 1.4e-45 154.4 0.4 1.8e-45 154.0 0.4 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BING4CT PF08149.11 EJP66102.1 - 6.3e-38 128.5 0.1 2.8e-35 120.0 0.0 3.1 4 0 0 4 4 4 2 BING4CT (NUC141) domain Coatomer_WDAD PF04053.14 EJP66102.1 - 0.00029 20.0 0.0 0.0052 15.9 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EJP66102.1 - 0.0019 19.0 0.1 0.87 10.6 0.0 3.7 4 1 1 5 5 5 1 WD domain, G-beta repeat RIBIOP_C PF04950.12 EJP66103.1 - 4.9e-106 354.4 0.0 1e-105 353.4 0.0 1.6 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EJP66103.1 - 6.9e-18 64.5 0.0 1.9e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.19 EJP66104.1 - 5.7e-34 117.2 0.0 8.2e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EJP66104.1 - 1.1e-05 24.5 0.7 0.00013 21.1 0.7 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EJP66104.1 - 0.011 16.3 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EJP66104.1 - 0.029 14.4 0.0 0.1 12.7 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EJP66104.1 - 0.043 14.2 0.0 0.054 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EJP66104.1 - 0.048 13.6 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain His_Phos_1 PF00300.22 EJP66105.1 - 4.3e-11 42.9 2.0 1.1e-10 41.5 2.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EF-hand_4 PF12763.7 EJP66107.1 - 0.00011 22.1 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EJP66107.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EJP66107.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair MAP65_ASE1 PF03999.12 EJP66108.1 - 2.6e-80 270.9 5.5 4.7e-80 270.0 5.6 1.3 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) F-actin_cap_A PF01267.17 EJP66108.1 - 0.12 11.8 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Peptidase_M61 PF05299.12 EJP66108.1 - 0.2 12.1 0.4 2 8.8 0.0 2.7 2 0 0 2 2 2 0 M61 glycyl aminopeptidase BRE1 PF08647.11 EJP66108.1 - 0.27 11.3 7.3 0.43 10.7 1.1 3.6 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase SKA2 PF16740.5 EJP66108.1 - 0.87 9.4 8.8 0.63 9.8 0.0 4.2 5 0 0 5 5 5 0 Spindle and kinetochore-associated protein 2 Occludin_ELL PF07303.13 EJP66108.1 - 1 10.1 8.6 0.67 10.7 0.5 3.5 2 2 0 2 2 2 0 Occludin homology domain XhlA PF10779.9 EJP66108.1 - 1.2 9.4 4.8 0.64 10.3 0.7 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Syntaxin-6_N PF09177.11 EJP66108.1 - 7.3 7.2 10.0 4.8 7.8 0.4 3.5 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Pkinase PF00069.25 EJP66109.1 - 4.4e-11 42.6 0.0 1.1e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 EJP66109.1 - 2.1e-09 36.8 2.5 0.14 12.5 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EJP66109.1 - 2.8e-08 34.0 0.2 6.6e-06 26.3 0.0 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EJP66109.1 - 6.8e-07 29.7 0.6 0.0012 19.3 0.4 3.6 4 0 0 4 4 4 2 HEAT-like repeat Pkinase_Tyr PF07714.17 EJP66109.1 - 1e-06 28.3 0.0 1.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EJP66109.1 - 2.1e-06 28.0 0.7 0.0001 22.6 0.2 3.4 2 1 3 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EJP66109.1 - 0.0014 19.2 0.1 2.9 8.5 0.0 2.9 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region Kinase-like PF14531.6 EJP66109.1 - 0.046 13.0 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TIP120 PF08623.10 EJP66109.1 - 0.094 12.5 0.1 1 9.1 0.1 2.2 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) SOG2 PF10428.9 EJP66109.1 - 2.1 7.4 6.8 4.4 6.4 6.8 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Aconitase PF00330.20 EJP66111.1 - 1.6e-145 485.7 0.0 2e-145 485.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EJP66111.1 - 5.8e-37 126.9 0.0 9.3e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Nucleopor_Nup85 PF07575.13 EJP66112.1 - 6.1e-17 61.4 0.0 1.2e-11 44.0 0.1 2.2 2 0 0 2 2 2 2 Nup85 Nucleoporin GvpO PF05800.11 EJP66112.1 - 0.0045 16.9 0.9 0.014 15.4 0.1 2.2 2 0 0 2 2 2 1 Gas vesicle synthesis protein GvpO Nsp1_C PF05064.13 EJP66112.1 - 0.045 13.6 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Nsp1-like C-terminal region cIII PF08134.11 EJP66112.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 cIII protein family Pkinase PF00069.25 EJP66113.1 - 4.1e-17 62.4 0.0 5.5e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66113.1 - 2.3e-15 56.6 0.0 7.2e-15 55.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP66113.1 - 0.0031 16.9 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL PF07366.12 EJP66115.1 - 2.4e-23 82.3 0.0 5e-20 71.6 0.0 2.6 3 0 0 3 3 3 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EJP66115.1 - 1.4e-12 48.2 0.5 3.4e-08 34.1 0.0 2.6 2 1 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.6 EJP66115.1 - 0.065 13.6 0.3 0.53 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 EJP66115.1 - 0.13 12.5 0.2 3.1 8.1 0.1 2.4 2 0 0 2 2 2 0 SnoaL-like domain Cutinase PF01083.22 EJP66117.1 - 3e-20 72.9 0.0 3.7e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EJP66117.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain F-box-like PF12937.7 EJP66119.1 - 2.4e-09 36.9 0.1 5.6e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP66119.1 - 1.3e-05 25.0 0.1 2.5e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain DUF3456 PF11938.8 EJP66120.1 - 0.016 15.8 0.0 0.024 15.2 0.0 1.2 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP SWIRM PF04433.17 EJP66121.1 - 8.1e-15 54.9 0.1 4.4e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 SWIRM domain GRIP PF01465.20 EJP66123.1 - 5.4e-16 58.2 0.1 1.2e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 GRIP domain Seryl_tRNA_N PF02403.22 EJP66123.1 - 0.00064 19.9 10.7 0.00064 19.9 10.7 11.8 1 1 11 13 13 13 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 EJP66123.1 - 0.0087 15.0 174.6 0.017 14.1 21.8 8.2 2 2 6 8 8 8 6 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EJP66123.1 - 0.009 16.0 13.9 0.009 16.0 13.9 9.6 2 2 7 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 EJP66123.1 - 0.011 15.5 0.6 0.011 15.5 0.6 14.3 7 4 9 16 16 16 0 Septum formation initiator K_channel_TID PF07941.11 EJP66123.1 - 0.11 13.0 1.5 1.4 9.4 1.5 3.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain GAS PF13851.6 EJP66123.1 - 8.6 5.6 167.3 0.14 11.5 15.6 9.4 3 3 6 9 9 9 0 Growth-arrest specific micro-tubule binding Ank_2 PF12796.7 EJP66124.1 - 1.1e-65 218.2 10.9 3e-12 47.0 0.3 7.0 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP66124.1 - 2.5e-52 168.7 18.3 0.00095 19.5 0.0 14.7 15 0 0 15 15 15 11 Ankyrin repeat Ank_4 PF13637.6 EJP66124.1 - 1.8e-50 168.7 15.0 3.6e-08 33.8 0.0 10.2 4 2 9 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP66124.1 - 3.2e-45 151.6 20.4 5e-08 33.1 0.1 10.2 4 3 6 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 EJP66124.1 - 1.8e-42 142.0 18.3 1.1e-05 25.6 0.0 13.4 13 0 0 13 13 13 12 Ankyrin repeat F-box-like PF12937.7 EJP66124.1 - 7.3e-06 25.8 0.0 2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP66124.1 - 0.002 18.0 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EJP66126.1 - 6.9e-12 45.7 3.8 0.08 13.8 0.0 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66126.1 - 0.034 14.5 0.0 27 5.1 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EJP66126.1 - 0.066 12.1 0.1 0.34 9.8 0.0 1.9 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SRR1 PF07985.12 EJP66127.1 - 7.4e-15 54.7 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 SRR1 DUF2247 PF10004.9 EJP66127.1 - 0.028 14.2 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Glyco_hydro_17 PF00332.18 EJP66128.1 - 1.5e-09 37.9 2.5 7.5e-07 29.0 0.6 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF2140 PF09911.9 EJP66128.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Rick_17kDa_Anti PF05433.15 EJP66128.1 - 0.039 13.8 0.4 0.039 13.8 0.4 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.9 EJP66128.1 - 0.24 11.5 12.0 0.17 12.1 2.7 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 EJP66128.1 - 0.28 11.2 14.4 0.85 9.7 0.3 2.4 2 0 0 2 2 2 0 Glycine zipper SNARE PF05739.19 EJP66128.1 - 0.36 10.9 0.9 0.63 10.1 0.9 1.4 1 0 0 1 1 1 0 SNARE domain MMADHC PF10229.9 EJP66129.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein Zn_clus PF00172.18 EJP66130.1 - 2.4e-09 37.2 7.8 2.4e-09 37.2 7.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP66130.1 - 2.8e-07 29.7 0.2 0.017 14.0 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Nsp3_PL2pro PF12124.8 EJP66131.1 - 0.0052 16.5 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 Coronavirus polyprotein cleavage domain VPS11_C PF12451.8 EJP66131.1 - 4.4 7.6 4.8 1.1 9.5 0.8 2.1 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal AAA_12 PF13087.6 EJP66132.1 - 4.8e-36 124.3 0.0 1.3e-35 122.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EJP66132.1 - 4.2e-28 98.8 3.5 5.7e-28 98.4 0.5 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EJP66132.1 - 4.2e-13 49.9 0.0 1.2e-06 28.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EJP66132.1 - 2.7e-11 43.5 0.0 1.5e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EJP66132.1 - 5.1e-06 26.4 0.0 0.36 10.5 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EJP66132.1 - 0.0028 17.2 0.1 0.0075 15.7 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.14 EJP66132.1 - 0.0043 16.9 0.0 0.98 9.2 0.0 2.4 2 0 0 2 2 2 1 Helicase DEAD PF00270.29 EJP66132.1 - 0.0052 16.6 0.3 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EJP66132.1 - 0.0052 16.8 0.1 0.062 13.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EJP66132.1 - 0.082 13.2 0.4 5 7.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain AvrB_AvrC PF05394.11 EJP66132.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Avirulence protein DUF2075 PF09848.9 EJP66132.1 - 0.14 11.3 0.2 0.79 8.9 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 EJP66132.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Pyr_redox_3 PF13738.6 EJP66133.1 - 2.4e-17 63.2 0.2 2.6e-14 53.2 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP66133.1 - 1.4e-15 57.3 0.0 1e-12 47.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EJP66133.1 - 8.8e-10 37.6 0.0 9e-08 31.0 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EJP66133.1 - 1.2e-07 31.3 0.1 2.3e-05 23.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EJP66133.1 - 7.8e-07 28.7 0.0 2.4e-05 23.8 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 EJP66133.1 - 4.1e-06 26.9 0.0 1.7e-05 25.0 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP66133.1 - 0.00027 20.1 0.1 0.00072 18.7 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EJP66133.1 - 0.00069 18.4 0.1 0.0038 16.0 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 EJP66133.1 - 0.0013 18.1 0.1 0.0097 15.3 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 EJP66133.1 - 0.0026 17.4 0.0 0.19 11.3 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EJP66133.1 - 0.0037 16.7 0.0 0.0094 15.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase IlvN PF07991.12 EJP66133.1 - 0.004 16.8 0.2 0.15 11.6 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 EJP66133.1 - 0.0046 16.1 0.0 0.086 11.9 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EJP66133.1 - 0.011 15.0 0.0 0.084 12.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EJP66133.1 - 0.034 14.7 0.1 1.3 9.7 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EJP66133.1 - 0.035 13.4 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 EJP66133.1 - 0.062 12.6 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EJP66133.1 - 0.064 13.3 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EJP66133.1 - 0.15 11.0 0.1 0.47 9.4 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein PUL PF08324.11 EJP66135.1 - 1e-67 228.3 0.1 1.4e-67 227.9 0.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EJP66135.1 - 1.4e-44 150.9 0.6 2.6e-44 150.1 0.6 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EJP66135.1 - 1e-30 105.3 10.2 1.9e-06 28.5 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66135.1 - 0.0051 17.1 1.3 12 6.3 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EJP66135.1 - 0.023 15.2 0.3 0.52 10.9 0.1 3.1 1 1 1 2 2 2 0 PQQ-like domain Metallophos PF00149.28 EJP66136.1 - 1e-09 39.2 0.1 1.6e-09 38.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP66136.1 - 2.2e-09 37.7 0.0 6.8e-08 32.9 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 EJP66136.1 - 0.0015 17.9 0.1 0.004 16.6 0.1 1.7 1 0 0 1 1 1 1 Transport inhibitor response 1 protein domain Fic PF02661.18 EJP66137.1 - 3.1e-20 72.9 0.0 4.3e-19 69.2 0.0 2.5 3 0 0 3 3 3 1 Fic/DOC family BAG6 PF12057.8 EJP66137.1 - 0.07 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 BCL2-associated athanogene 6 Pkinase PF00069.25 EJP66138.1 - 1.2e-21 77.3 0.0 5.8e-21 75.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66138.1 - 0.00032 20.1 0.1 0.0011 18.3 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP66138.1 - 0.0041 17.1 0.2 0.0089 16.0 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EJP66138.1 - 0.22 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DAPG_hydrolase PF18089.1 EJP66139.1 - 4e-46 157.4 1.3 6.8e-45 153.3 1.3 2.1 1 1 0 1 1 1 1 DAPG hydrolase PhiG domain APH PF01636.23 EJP66141.1 - 0.0096 15.9 0.1 0.022 14.7 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Transthyretin PF00576.21 EJP66143.1 - 2e-35 121.8 0.0 2.3e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 EJP66143.1 - 0.0055 17.0 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain MG4 PF17789.1 EJP66143.1 - 0.074 13.2 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 Macroglobulin domain MG4 WD40 PF00400.32 EJP66144.1 - 6e-21 74.4 4.4 5.5e-09 36.5 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66144.1 - 6.5e-05 23.2 0.0 0.15 12.4 0.0 4.0 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP66144.1 - 0.00015 20.9 0.0 0.028 13.4 0.0 2.4 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein HCO3_cotransp PF00955.21 EJP66145.1 - 1.4e-70 238.5 13.9 7.9e-42 143.7 5.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family SET PF00856.28 EJP66146.1 - 2e-12 47.8 0.1 1.3e-09 38.7 0.0 2.7 2 1 1 3 3 3 2 SET domain Mgm101p PF06420.12 EJP66146.1 - 0.038 13.5 0.1 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Trypsin PF00089.26 EJP66147.1 - 4.6e-40 137.8 0.2 5.8e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP66147.1 - 3.3e-08 34.5 0.1 6.1e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF4448 PF14610.6 EJP66148.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM52 PF14979.6 EJP66148.1 - 0.0037 17.2 0.2 0.0069 16.3 0.2 1.4 1 0 0 1 1 1 1 Transmembrane 52 TMEM154 PF15102.6 EJP66148.1 - 0.0053 16.7 0.3 0.41 10.5 0.0 2.5 2 1 0 2 2 2 1 TMEM154 protein family Shisa PF13908.6 EJP66148.1 - 0.017 15.4 0.4 0.017 15.4 0.4 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DAG1 PF05454.11 EJP66148.1 - 0.049 13.0 0.1 0.07 12.5 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Adeno_E3_CR2 PF02439.15 EJP66148.1 - 0.055 13.2 8.6 0.12 12.2 8.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VIT PF08487.10 EJP66149.1 - 1.1e-32 112.6 0.4 1.1e-32 112.6 0.4 2.6 2 0 0 2 2 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EJP66149.1 - 9.6e-28 97.1 0.0 9.6e-28 97.1 0.0 2.1 2 0 0 2 2 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EJP66149.1 - 2.7e-15 56.0 0.2 8.2e-15 54.5 0.2 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 EJP66149.1 - 1e-06 29.3 4.1 1.7e-06 28.6 0.0 3.0 2 1 0 2 2 1 1 von Willebrand factor type A domain Pex14_N PF04695.13 EJP66149.1 - 0.0061 17.2 14.0 0.022 15.4 14.0 1.9 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Draxin PF15550.6 EJP66149.1 - 0.012 15.5 4.7 0.021 14.7 4.7 1.3 1 0 0 1 1 1 0 Draxin DUF1655 PF07868.11 EJP66149.1 - 0.015 15.3 0.1 0.039 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) DDHD PF02862.17 EJP66149.1 - 0.045 13.9 4.5 0.087 13.0 4.5 1.4 1 0 0 1 1 1 0 DDHD domain DUF3371 PF11851.8 EJP66149.1 - 0.06 14.4 14.2 0.19 12.8 14.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Neur_chan_memb PF02932.16 EJP66149.1 - 0.089 12.8 3.4 0.16 12.0 3.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Bul1_N PF04425.12 EJP66149.1 - 0.22 10.3 8.1 0.34 9.6 8.1 1.2 1 0 0 1 1 1 0 Bul1 N terminus EOS1 PF12326.8 EJP66149.1 - 0.23 11.4 0.2 0.44 10.5 0.2 1.5 1 0 0 1 1 1 0 N-glycosylation protein CLN3 PF02487.17 EJP66149.1 - 0.41 9.6 2.2 0.64 9.0 2.2 1.2 1 0 0 1 1 1 0 CLN3 protein Med15 PF09606.10 EJP66149.1 - 0.42 9.3 36.3 0.66 8.6 36.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EPL1 PF10513.9 EJP66149.1 - 0.82 10.0 11.7 0.96 9.8 9.6 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like Suf PF05843.14 EJP66149.1 - 0.96 9.4 20.9 1.8 8.5 20.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SpoIIP PF07454.11 EJP66149.1 - 1.2 8.6 12.0 2.1 7.7 12.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spt20 PF12090.8 EJP66149.1 - 1.2 8.7 39.9 7.1 6.2 40.1 2.2 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 EJP66149.1 - 1.3 10.1 13.4 4.6 8.3 13.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 EJP66149.1 - 1.6 7.5 33.4 0.22 10.4 28.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RR_TM4-6 PF06459.12 EJP66149.1 - 2.1 8.1 12.4 6 6.6 12.4 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTPRCAP PF15713.5 EJP66149.1 - 2.6 8.3 20.1 0.078 13.3 13.0 2.0 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated PepSY_TM PF03929.16 EJP66149.1 - 2.9 7.5 6.0 5.3 6.6 6.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM region EIIBC-GUT_N PF03612.14 EJP66149.1 - 3 7.6 9.8 7.1 6.3 9.8 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CPSF100_C PF13299.6 EJP66149.1 - 3.5 7.8 8.2 11 6.2 8.2 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EJP66149.1 - 3.6 6.2 16.0 6.1 5.5 16.0 1.2 1 0 0 1 1 1 0 Presenilin BORG_CEP PF14957.6 EJP66149.1 - 4.1 8.6 9.3 15 6.8 9.3 1.9 1 0 0 1 1 1 0 Cdc42 effector Tim54 PF11711.8 EJP66149.1 - 4.7 5.9 10.8 8.7 5.0 10.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4407 PF14362.6 EJP66149.1 - 5 6.4 12.3 9.5 5.5 12.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EIF4E-T PF10477.9 EJP66149.1 - 6.9 5.4 23.2 11 4.8 23.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Hid1 PF12722.7 EJP66149.1 - 9.1 4.3 11.0 13 3.7 11.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Acyl_transf_3 PF01757.22 EJP66150.1 - 4e-30 105.1 12.1 6e-30 104.5 12.1 1.3 1 1 0 1 1 1 1 Acyltransferase family Macoilin PF09726.9 EJP66151.1 - 2.2 6.7 13.2 2.7 6.4 13.2 1.1 1 0 0 1 1 1 0 Macoilin family Abhydrolase_1 PF00561.20 EJP66152.1 - 1.5e-21 77.2 0.1 2.1e-20 73.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP66152.1 - 3.3e-17 63.8 4.8 6.2e-17 62.9 4.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP66152.1 - 7.7e-08 31.9 0.0 3.1e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EJP66152.1 - 0.039 12.9 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.14 EJP66152.1 - 0.051 12.3 0.0 0.45 9.2 0.0 1.9 2 0 0 2 2 2 0 Ndr family Fungal_trans_2 PF11951.8 EJP66153.1 - 6.9e-12 44.9 0.1 9e-12 44.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66153.1 - 3.5e-07 30.2 8.1 6.4e-07 29.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EJP66154.1 - 6.6e-92 308.7 26.9 7.5e-92 308.5 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP66154.1 - 9e-31 107.1 58.0 3.2e-26 92.1 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_5 PF13346.6 EJP66154.1 - 0.0012 18.4 10.5 0.0012 18.4 10.5 3.5 3 1 1 4 4 4 1 ABC-2 family transporter protein OATP PF03137.20 EJP66154.1 - 0.019 13.3 20.7 0.0047 15.3 1.8 3.2 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 EJP66155.1 - 1.9e-54 185.2 0.0 3.1e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 KR PF08659.10 EJP66156.1 - 3.9e-35 121.4 0.7 7.2e-20 71.6 0.1 2.4 1 1 1 2 2 2 2 KR domain ADH_zinc_N_2 PF13602.6 EJP66156.1 - 9.3e-21 75.3 0.0 2.1e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EJP66156.1 - 1.9e-15 57.0 0.0 3.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EJP66156.1 - 9.7e-05 22.6 0.4 0.00028 21.2 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ABC_tran PF00005.27 EJP66157.1 - 4.6e-38 130.8 0.0 1.4e-18 67.8 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EJP66157.1 - 1.9e-23 83.5 32.4 2.6e-18 66.7 17.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region PS-DH PF14765.6 EJP66157.1 - 1.3e-17 64.0 0.0 2.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EJP66157.1 - 8.6e-16 58.5 0.0 2.5e-14 53.8 0.0 3.3 3 1 0 3 3 3 1 Methyltransferase domain SMC_N PF02463.19 EJP66157.1 - 2.8e-10 40.0 1.1 0.016 14.7 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain Methyltransf_23 PF13489.6 EJP66157.1 - 3.8e-08 33.3 0.0 8.7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP66157.1 - 7.7e-08 33.0 0.0 3.6e-07 30.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain AAA_21 PF13304.6 EJP66157.1 - 6.6e-07 29.4 0.2 0.26 11.1 0.2 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Methyltransf_11 PF08241.12 EJP66157.1 - 5.6e-06 26.9 0.0 0.00011 22.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP66157.1 - 1.9e-05 24.5 0.0 4.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AAA_29 PF13555.6 EJP66157.1 - 5.2e-05 22.9 0.5 0.016 15.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJP66157.1 - 5.7e-05 23.2 0.1 0.4 10.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP66157.1 - 5.9e-05 23.0 0.2 0.32 10.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 EJP66157.1 - 0.0005 20.3 0.4 0.99 9.7 0.0 3.1 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 EJP66157.1 - 0.00073 19.6 1.8 0.12 12.4 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 EJP66157.1 - 0.0029 17.9 0.1 2.4 8.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EJP66157.1 - 0.0043 17.5 0.0 0.59 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EJP66157.1 - 0.0062 15.7 0.1 2.1 7.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_15 PF13175.6 EJP66157.1 - 0.0095 15.7 0.2 3.5 7.2 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 EJP66157.1 - 0.017 15.0 0.4 5.5 6.9 0.0 3.3 3 0 0 3 3 3 0 NACHT domain AAA PF00004.29 EJP66157.1 - 0.019 15.4 0.0 18 5.7 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 EJP66157.1 - 0.033 13.2 0.3 0.35 9.8 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EJP66157.1 - 0.11 13.1 0.0 0.65 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EJP66157.1 - 0.12 12.8 0.4 7.5 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EJP66157.1 - 0.14 11.4 0.1 4.4 6.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EJP66157.1 - 0.17 12.3 0.1 40 4.7 0.1 3.0 3 0 0 3 3 3 0 RNA helicase PRK PF00485.18 EJP66157.1 - 0.2 11.4 0.2 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DoxX_2 PF13564.6 EJP66157.1 - 0.81 9.8 14.7 3.2 7.9 0.3 3.9 3 0 0 3 3 3 0 DoxX-like family MFS_1 PF07690.16 EJP66158.1 - 5.4e-18 65.0 31.3 5.4e-18 65.0 31.3 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily ApoL PF05461.11 EJP66158.1 - 4.5 6.5 6.0 4.7 6.5 3.4 1.9 2 0 0 2 2 2 0 Apolipoprotein L TssN PF17555.2 EJP66158.1 - 8.9 5.6 12.9 0.12 11.7 2.5 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssN Fungal_trans PF04082.18 EJP66159.1 - 1e-10 41.1 0.5 2.4e-10 39.9 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66159.1 - 3.8e-05 23.7 8.3 3.8e-05 23.7 8.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP_hydrolase PF09370.10 EJP66160.1 - 9e-130 431.7 1.9 1e-129 431.5 1.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like Chorion_1 PF01723.16 EJP66160.1 - 0.028 14.4 4.9 0.05 13.6 4.9 1.4 1 0 0 1 1 1 0 Chorion protein UPF0261 PF06792.11 EJP66161.1 - 8.9e-152 505.7 0.0 1e-151 505.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Crystall_3 PF08964.10 EJP66162.1 - 0.018 15.2 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin N2227 PF07942.12 EJP66165.1 - 6.5e-48 163.3 0.0 1.1e-47 162.6 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 EJP66165.1 - 3.4e-06 27.6 0.0 1.3e-05 25.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP66165.1 - 9.9e-05 23.0 0.0 0.00026 21.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP66165.1 - 0.0003 21.4 0.0 0.0011 19.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP66165.1 - 0.0022 17.9 0.0 0.0048 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP66165.1 - 0.023 14.5 0.1 0.072 12.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 EJP66165.1 - 0.027 15.5 0.0 0.25 12.4 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_8 PF05148.15 EJP66165.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 EJP66165.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family YMF19 PF02326.15 EJP66165.1 - 3.3 8.6 7.5 4.4 8.2 1.4 2.7 2 0 0 2 2 2 0 Plant ATP synthase F0 Tyrosinase PF00264.20 EJP66166.1 - 7.1e-40 137.6 8.7 1.2e-39 136.9 8.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3328 PF11807.8 EJP66167.1 - 1.2e-21 77.5 1.7 2.7e-21 76.4 1.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_25 PF13649.6 EJP66169.1 - 1.7e-05 25.4 0.0 5.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EJP66169.1 - 2.7e-05 24.0 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EJP66169.1 - 0.00018 21.4 0.2 0.00049 19.9 0.3 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP66169.1 - 0.0015 17.9 0.0 0.0035 16.7 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EJP66169.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EJP66169.1 - 0.015 15.9 0.0 0.085 13.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 EJP66169.1 - 0.02 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.19 EJP66169.1 - 0.042 14.0 0.1 0.078 13.1 0.1 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 EJP66169.1 - 0.043 13.4 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 EJP66169.1 - 0.075 14.1 0.0 0.16 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EJP66169.1 - 0.076 13.8 0.0 0.25 12.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Glyco_transf_90 PF05686.12 EJP66170.1 - 8.3e-15 54.6 3.3 1.6e-12 47.0 0.6 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 SapC PF07277.11 EJP66170.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 SapC PALP PF00291.25 EJP66171.1 - 1.8e-63 214.7 1.6 2.4e-63 214.3 1.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3343 PF11823.8 EJP66171.1 - 0.033 13.6 0.1 0.091 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) DegT_DnrJ_EryC1 PF01041.17 EJP66171.1 - 0.036 13.4 0.1 0.062 12.6 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.12 EJP66172.1 - 7.7e-46 155.7 0.0 1.2e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EJP66172.1 - 5.8e-40 136.9 0.0 8.7e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 EJP66172.1 - 0.034 14.3 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EJP66172.1 - 0.13 12.9 0.2 0.35 11.5 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UQ_con PF00179.26 EJP66173.1 - 6.1e-36 123.2 0.0 8e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1 PF01644.17 EJP66174.1 - 1.5e-69 233.1 0.0 2.2e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EJP66174.1 - 1.4e-27 95.4 0.0 2.6e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EJP66174.1 - 1.2e-25 90.1 0.0 3.3e-21 75.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EJP66174.1 - 2.6e-07 30.8 9.0 2.7e-06 27.4 9.0 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EJP66174.1 - 0.021 14.7 0.0 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Flavoprotein PF02441.19 EJP66175.1 - 2.2e-13 50.2 0.0 2.6e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein UbiD PF01977.16 EJP66176.1 - 6.6e-113 377.6 0.0 7.6e-113 377.4 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Glutaminase PF04960.15 EJP66176.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutaminase Opy2 PF09463.10 EJP66177.1 - 4.8e-09 36.4 16.4 8.5e-09 35.6 16.4 1.4 1 0 0 1 1 1 1 Opy2 protein Ras PF00071.22 EJP66178.1 - 2.5e-51 173.5 0.0 4.9e-51 172.5 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EJP66178.1 - 1.8e-17 63.7 0.0 1.6e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP66178.1 - 0.00057 19.4 0.0 0.0016 17.9 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EJP66178.1 - 0.02 14.8 0.0 6 6.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 EJP66178.1 - 0.023 14.2 0.1 0.38 10.3 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_16 PF13191.6 EJP66178.1 - 0.064 13.6 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Abhydrolase_4 PF08386.10 EJP66178.1 - 0.094 12.8 0.0 0.24 11.6 0.0 1.7 2 1 0 2 2 2 0 TAP-like protein AAA_25 PF13481.6 EJP66178.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EJP66178.1 - 0.16 11.3 0.0 0.32 10.2 0.0 1.5 2 0 0 2 2 2 0 Septin MMR_HSR1 PF01926.23 EJP66178.1 - 0.17 12.0 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4632 PF15451.6 EJP66179.1 - 0.0035 17.4 0.9 0.11 12.5 0.7 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4632) Bd3614-deam PF14439.6 EJP66179.1 - 0.03 14.4 1.7 0.04 14.0 1.7 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase CENP-B_dimeris PF09026.10 EJP66179.1 - 0.032 14.6 2.0 0.046 14.1 2.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LamB_YcsF PF03746.16 EJP66180.1 - 5.3e-66 222.7 0.8 5.5e-39 134.3 0.5 2.0 1 1 1 2 2 2 2 LamB/YcsF family UNC-93 PF05978.16 EJP66181.1 - 1.7e-08 34.3 5.2 4.6e-08 32.9 5.2 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EJP66181.1 - 1.7e-07 30.5 37.0 1.7e-07 30.5 37.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF730 PF05325.11 EJP66182.1 - 0.009 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF730) S6OS1 PF15676.5 EJP66182.1 - 0.049 12.1 0.1 0.069 11.6 0.1 1.2 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Amidase PF01425.21 EJP66183.1 - 1.6e-102 343.8 0.0 1.5e-101 340.6 0.0 1.9 1 1 0 1 1 1 1 Amidase DUF1953 PF09196.10 EJP66184.1 - 0.07 12.9 0.6 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1953) SPOUT_MTase PF02590.17 EJP66184.1 - 0.21 11.5 0.0 6 6.8 0.0 2.2 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Trypsin PF00089.26 EJP66185.1 - 6.7e-39 134.0 0.1 8.5e-39 133.6 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP66185.1 - 6.1e-10 40.2 0.1 1e-09 39.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain CT_A_B PF02626.15 EJP66186.1 - 2e-72 244.0 0.0 3e-72 243.4 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 EJP66186.1 - 2.7e-56 190.4 0.0 5.2e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 EJP66186.1 - 1.2e-33 116.6 0.0 4.2e-33 114.8 0.0 1.9 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 EJP66186.1 - 8.5e-31 106.8 0.4 2.4e-30 105.3 0.1 2.0 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EJP66186.1 - 2.8e-30 104.6 0.0 7e-30 103.3 0.0 1.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EJP66186.1 - 7.2e-09 35.4 3.7 2.8e-08 33.5 3.7 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EJP66186.1 - 5.3e-06 26.1 0.0 9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EJP66186.1 - 0.011 15.6 2.1 0.22 11.4 0.2 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like ATP-grasp PF02222.22 EJP66186.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 EJP66186.1 - 0.072 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Nebulin PF00880.18 EJP66186.1 - 0.2 11.6 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Nebulin repeat Ribosomal_L6e PF01159.19 EJP66186.1 - 1 9.9 3.0 2.7 8.6 3.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L6e Fungal_trans_2 PF11951.8 EJP66187.1 - 7.7e-37 127.0 5.7 1e-36 126.6 5.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66187.1 - 1e-11 44.7 7.8 2.2e-11 43.7 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP66187.1 - 0.0052 15.8 0.2 0.0052 15.8 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain HAD_2 PF13419.6 EJP66188.1 - 3.1e-10 40.4 0.0 4.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP66188.1 - 3.2e-10 40.6 0.0 4.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP66188.1 - 2.8e-07 30.5 0.0 5.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like ATPgrasp_N PF18130.1 EJP66188.1 - 0.3 11.7 1.7 1.4 9.5 0.1 2.5 3 0 0 3 3 3 0 ATP-grasp N-terminal domain Zn_clus PF00172.18 EJP66189.1 - 3.7e-06 26.9 11.5 3.7e-06 26.9 11.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhodanese PF00581.20 EJP66190.1 - 8.8e-29 100.2 0.0 4.7e-07 30.3 0.0 4.4 4 0 0 4 4 4 4 Rhodanese-like domain TPR_7 PF13176.6 EJP66191.1 - 3e-06 26.9 4.6 0.012 15.6 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJP66191.1 - 3.8e-06 26.5 6.7 1.1e-05 25.0 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJP66191.1 - 0.00096 18.8 3.7 0.006 16.3 0.1 3.6 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 EJP66191.1 - 0.0015 18.6 0.7 0.32 11.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EJP66191.1 - 0.0015 18.5 0.4 0.0015 18.5 0.4 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJP66191.1 - 0.0074 16.6 10.1 3.2 8.1 0.5 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP66191.1 - 0.028 14.9 1.5 5.3 7.6 0.3 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP66191.1 - 0.057 14.3 13.0 38 5.5 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EJP66191.1 - 1.7 8.6 6.2 2.9 7.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DIOX_N PF14226.6 EJP66192.1 - 1.5e-21 77.4 0.0 1.3e-20 74.3 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EJP66192.1 - 2.2e-14 53.8 0.0 3.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EJP66193.1 - 9.8e-29 100.4 26.4 1.2e-28 100.0 26.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Mcp5_PH PF12814.7 EJP66194.1 - 1.2e-46 157.8 0.0 2.9e-46 156.6 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.12 EJP66194.1 - 0.00087 19.3 16.2 0.0028 17.7 8.5 2.5 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein DUF2959 PF11172.8 EJP66194.1 - 0.015 15.5 6.1 0.03 14.5 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) GAS PF13851.6 EJP66194.1 - 0.022 14.1 13.9 0.041 13.2 13.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TACC_C PF05010.14 EJP66194.1 - 0.07 12.9 11.6 0.11 12.2 11.6 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DivIC PF04977.15 EJP66194.1 - 0.19 11.5 6.7 0.088 12.6 0.3 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF724 PF05266.14 EJP66194.1 - 0.2 11.5 7.5 0.11 12.3 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Fez1 PF06818.15 EJP66194.1 - 0.42 11.0 16.9 0.087 13.3 13.0 1.8 2 0 0 2 2 1 0 Fez1 CENP-H PF05837.12 EJP66194.1 - 2.6 8.5 11.5 2.2 8.7 3.5 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Atg14 PF10186.9 EJP66194.1 - 3.2 6.7 8.9 6.9 5.6 8.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EJP66194.1 - 3.5 6.4 13.4 5.8 5.7 13.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EJP66194.1 - 3.8 6.8 6.6 7.6 5.8 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_76 PF03663.14 EJP66195.1 - 7.6e-136 453.4 11.1 8.8e-136 453.2 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EJP66195.1 - 0.53 9.3 8.4 3.6 6.6 0.5 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 DUF2321 PF10083.9 EJP66196.1 - 0.053 13.2 0.4 0.066 12.8 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) E1-E2_ATPase PF00122.20 EJP66197.1 - 2.4e-40 138.0 1.6 9.6e-40 136.0 0.6 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EJP66197.1 - 1e-30 106.8 6.3 1e-30 106.8 6.3 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EJP66197.1 - 1.2e-24 87.8 0.1 3.3e-13 50.4 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJP66197.1 - 7e-13 48.5 0.0 1.8e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EJP66197.1 - 4.7e-10 39.0 0.0 1.2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP66197.1 - 0.00023 21.0 0.3 0.00047 20.0 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.9 EJP66197.1 - 0.0078 16.6 0.7 0.0078 16.6 0.7 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2231) HAD PF12710.7 EJP66197.1 - 0.015 15.7 0.0 0.14 12.6 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase LEP503 PF15221.6 EJP66197.1 - 0.13 12.6 0.2 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 DUF2157 PF09925.9 EJP66197.1 - 2.2 8.0 9.5 3 7.6 0.3 3.3 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) INO80_Ies4 PF08193.11 EJP66198.1 - 1.8e-77 260.6 21.2 1.8e-77 260.6 21.2 1.6 1 1 1 2 2 2 1 INO80 complex subunit Ies4 CLTH PF10607.9 EJP66199.1 - 1.1e-30 106.5 0.6 1.6e-30 106.0 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EJP66199.1 - 1.7e-24 86.2 0.2 2.9e-24 85.5 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EJP66199.1 - 2.2e-05 24.3 0.1 8.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 LisH GST_N_4 PF17172.4 EJP66200.1 - 5e-20 72.1 0.0 1.6e-19 70.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EJP66200.1 - 1.1e-12 47.5 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EJP66200.1 - 2.9e-11 43.7 0.1 5.5e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 EJP66200.1 - 0.021 14.9 2.0 0.056 13.5 1.7 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 EJP66200.1 - 0.022 15.0 0.0 0.18 12.0 0.0 2.1 1 1 1 2 2 2 0 SAM35, subunit of SAM coomplex OTU PF02338.19 EJP66201.1 - 3.5e-18 66.3 3.4 6.2e-18 65.5 0.0 3.0 2 2 1 3 3 3 1 OTU-like cysteine protease MFMR_assoc PF16596.5 EJP66201.1 - 0.011 16.2 4.8 0.011 16.2 4.8 1.8 2 0 0 2 2 2 0 Disordered region downstream of MFMR Peptidase_C65 PF10275.9 EJP66201.1 - 0.017 14.6 0.0 1.3 8.4 0.0 2.8 1 1 0 3 3 3 0 Peptidase C65 Otubain DUF1387 PF07139.11 EJP66201.1 - 1.3 8.7 17.2 1.8 8.2 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) NAD_binding_4 PF07993.12 EJP66201.1 - 5.5 6.1 7.3 0.25 10.5 1.4 1.7 2 0 0 2 2 2 0 Male sterility protein Draxin PF15550.6 EJP66201.1 - 7.6 6.3 17.9 6.1 6.6 16.6 1.5 1 1 1 2 2 2 0 Draxin TPMT PF05724.11 EJP66202.1 - 1.7e-26 93.2 0.0 2.4e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 EJP66202.1 - 9.5e-09 35.3 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP66202.1 - 6.2e-06 26.8 0.0 2.1e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP66202.1 - 1.1e-05 25.3 0.0 8.8e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP66202.1 - 4.5e-05 24.0 0.0 0.00016 22.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP66202.1 - 0.00011 22.9 0.0 0.00083 20.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EJP66202.1 - 0.0045 16.4 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB adh_short_C2 PF13561.6 EJP66203.1 - 1.9e-42 145.4 0.5 2.6e-42 145.0 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP66203.1 - 9.9e-37 126.3 0.5 1.5e-36 125.7 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EJP66203.1 - 3.1e-06 27.2 0.5 9.4e-06 25.7 0.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP66203.1 - 0.13 11.7 0.2 1 8.8 0.2 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_11 PF14833.6 EJP66204.1 - 0.017 15.4 0.4 0.021 15.0 0.4 1.2 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PAP1 PF08601.10 EJP66204.1 - 0.018 14.8 8.0 0.019 14.7 8.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Fungal_trans PF04082.18 EJP66209.1 - 5.1e-22 78.2 0.2 1.8e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66209.1 - 2.2e-08 34.1 10.1 4.2e-08 33.2 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fic PF02661.18 EJP66210.1 - 0.026 15.4 0.0 0.056 14.3 0.0 1.5 1 1 0 1 1 1 0 Fic/DOC family p450 PF00067.22 EJP66212.1 - 1.4e-39 136.2 0.0 1.9e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 P63C PF10546.9 EJP66212.1 - 0.039 14.5 0.0 0.73 10.5 0.1 2.3 2 0 0 2 2 2 0 P63C domain STAC2_u1 PF16664.5 EJP66212.1 - 0.18 12.3 0.4 0.39 11.2 0.1 1.6 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 MFS_1 PF07690.16 EJP66213.1 - 3.6e-42 144.6 29.8 3.6e-42 144.6 29.8 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP66213.1 - 2.8e-10 39.7 7.4 2.8e-10 39.7 7.4 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 EJP66213.1 - 0.0031 16.8 9.1 0.0031 16.8 9.1 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CYSTM PF12734.7 EJP66213.1 - 0.39 11.1 1.2 1.2 9.5 1.2 1.9 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance CDC45 PF02724.14 EJP66215.1 - 3.1 6.0 23.3 5.2 5.2 23.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Alanine_zipper PF11839.8 EJP66215.1 - 9.6 6.7 14.4 1.7 9.0 9.5 2.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DUF3012 PF11216.8 EJP66216.1 - 0.72 9.9 5.2 28 4.9 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3012) DEC-1_N PF04625.13 EJP66217.1 - 1.4 7.8 9.6 1.4 7.9 9.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AMP-binding PF00501.28 EJP66218.1 - 1.8e-69 234.4 0.0 2.4e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EJP66218.1 - 1.3e-18 66.6 0.1 3.1e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EJP66218.1 - 8.9e-17 61.8 0.0 2.4e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAP_N PF01213.19 EJP66218.1 - 7.2 6.0 8.4 11 5.3 8.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal BRCT_2 PF16589.5 EJP66219.1 - 0.00045 20.6 0.0 0.0009 19.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EJP66219.1 - 0.0005 20.0 0.3 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EJP66219.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain KilA-N PF04383.13 EJP66220.1 - 0.00013 21.8 0.0 0.0038 17.1 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Fungal_TACC PF12709.7 EJP66221.1 - 8.7e-12 45.3 12.3 1.5e-09 38.1 3.1 3.5 3 0 0 3 3 3 2 Fungal Transforming acidic coiled-coil (TACC) proteins TSC22 PF01166.18 EJP66221.1 - 3.8e-05 23.9 3.8 0.0074 16.6 0.0 3.1 3 0 0 3 3 3 2 TSC-22/dip/bun family GIT_CC PF16559.5 EJP66221.1 - 0.03 14.2 2.1 1.8 8.5 0.0 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FTCD_C PF04961.12 EJP66221.1 - 0.068 12.9 5.4 0.18 11.6 5.4 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Shugoshin_N PF07558.11 EJP66221.1 - 0.19 11.6 5.7 0.61 10.0 0.5 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.6 EJP66221.1 - 1.3 9.2 4.2 6.6 6.9 0.2 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain CASP_C PF08172.12 EJP66221.1 - 2.3 7.5 17.6 2 7.7 0.4 2.7 2 0 0 2 2 2 0 CASP C terminal LPP PF04728.13 EJP66221.1 - 8 6.9 7.3 40 4.7 0.0 4.0 4 0 0 4 4 4 0 Lipoprotein leucine-zipper bZIP_1 PF00170.21 EJP66221.1 - 8.6 6.5 14.4 0.16 12.1 1.6 3.4 4 0 0 4 4 4 0 bZIP transcription factor Amidohydro_2 PF04909.14 EJP66222.1 - 6.4e-27 95.1 0.9 7.7e-27 94.8 0.9 1.1 1 0 0 1 1 1 1 Amidohydrolase ABC_membrane PF00664.23 EJP66223.1 - 6.8e-79 265.3 40.7 7.6e-40 137.3 11.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP66223.1 - 3.3e-63 212.3 0.0 2e-30 106.1 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP66223.1 - 2e-14 53.6 0.0 3.7e-05 23.3 0.5 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EJP66223.1 - 3.9e-07 30.1 0.0 0.0078 16.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 EJP66223.1 - 4.1e-07 30.5 1.6 0.044 14.2 0.0 3.8 3 1 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EJP66223.1 - 5e-07 29.8 0.0 0.0036 17.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EJP66223.1 - 8.1e-07 28.7 0.8 0.0014 18.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EJP66223.1 - 1.1e-06 28.5 0.7 0.033 13.9 0.1 3.7 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 EJP66223.1 - 1.3e-06 27.5 0.8 0.054 12.3 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EJP66223.1 - 3e-06 27.5 0.4 0.2 12.0 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 EJP66223.1 - 1e-05 25.5 0.2 0.84 9.4 0.0 3.8 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 EJP66223.1 - 8.7e-05 22.3 0.1 0.19 11.4 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 EJP66223.1 - 0.00021 21.7 0.3 19 5.7 0.0 4.5 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 EJP66223.1 - 0.00075 19.3 0.0 0.24 11.1 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 EJP66223.1 - 0.00076 19.8 0.1 2.1 8.6 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EJP66223.1 - 0.00089 18.9 0.9 1.3 8.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EJP66223.1 - 0.0011 19.0 0.1 2 8.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EJP66223.1 - 0.0013 18.3 0.0 2.1 7.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EJP66223.1 - 0.0035 17.9 0.0 1.5 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EJP66223.1 - 0.0039 17.1 0.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 EJP66223.1 - 0.0074 16.5 6.8 0.78 10.0 0.2 4.8 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EJP66223.1 - 0.0078 16.7 6.3 0.051 14.1 0.1 2.6 2 1 1 3 3 2 1 AAA domain AAA_14 PF13173.6 EJP66223.1 - 0.013 15.6 0.0 1.5 8.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EJP66223.1 - 0.043 14.0 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EJP66223.1 - 0.062 12.9 0.1 8 6.0 0.0 2.6 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain DUF3987 PF13148.6 EJP66223.1 - 0.069 12.2 0.2 0.18 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NB-ARC PF00931.22 EJP66223.1 - 0.087 12.0 0.2 9.6 5.3 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain G-alpha PF00503.20 EJP66223.1 - 0.093 11.9 0.3 6 5.9 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 EJP66223.1 - 0.1 13.0 0.1 27 5.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 EJP66223.1 - 0.13 12.0 0.1 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 EJP66223.1 - 0.15 12.2 0.2 0.78 9.8 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Gtr1_RagA PF04670.12 EJP66223.1 - 0.17 11.2 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 EJP66223.1 - 0.17 12.1 0.1 30 4.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EJP66223.1 - 0.2 11.4 1.6 14 5.3 0.6 2.7 2 1 1 3 3 3 0 AAA domain AMPK1_CBM PF16561.5 EJP66224.1 - 0.0019 18.4 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Senescence_reg PF04520.13 EJP66224.1 - 0.61 10.9 15.7 1.1 10.0 15.7 1.5 1 0 0 1 1 1 0 Senescence regulator Presenilin PF01080.17 EJP66224.1 - 0.65 8.7 10.7 0.83 8.3 10.7 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EJP66224.1 - 1.1 7.4 10.7 1.3 7.0 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tmemb_cc2 PF10267.9 EJP66224.1 - 1.4 8.0 10.2 2.1 7.4 10.2 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SpoIIIAH PF12685.7 EJP66224.1 - 1.5 8.6 10.9 2.4 7.9 10.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein NPR3 PF03666.13 EJP66224.1 - 3.6 6.3 16.1 4.9 5.8 16.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec3_C PF09763.9 EJP66224.1 - 5.8 5.2 12.7 7.2 4.9 12.7 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 LSM PF01423.22 EJP66225.1 - 8.2e-20 70.3 0.0 1e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain ADH_N_2 PF16884.5 EJP66225.1 - 0.037 13.9 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase RWD PF05773.22 EJP66227.1 - 0.13 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 RWD domain Pkinase PF00069.25 EJP66228.1 - 1e-23 84.1 0.0 6.2e-16 58.6 0.0 3.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66228.1 - 2.5e-09 36.8 0.0 0.0013 18.1 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Collagen PF01391.18 EJP66229.1 - 1.1e-14 53.9 62.4 2.9e-08 33.3 27.7 3.5 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF3015 PF11220.8 EJP66230.1 - 0.00036 20.4 1.0 0.00095 19.0 1.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3015) DUF2015 PF09435.10 EJP66230.1 - 0.094 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) Metal_resist PF13801.6 EJP66230.1 - 0.3 11.3 6.6 0.3 11.3 3.9 2.0 1 1 1 2 2 2 0 Heavy-metal resistance zf-FPG_IleRS PF06827.14 EJP66231.1 - 0.0032 17.3 2.2 0.085 12.7 0.1 2.3 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS Mut7-C PF01927.16 EJP66231.1 - 0.036 14.2 0.5 0.041 14.0 0.5 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain Yippee-Mis18 PF03226.14 EJP66231.1 - 0.082 13.1 2.0 0.14 12.4 2.0 1.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Tox-PL-2 PF15643.6 EJP66231.1 - 0.59 10.3 2.1 9.5 6.4 0.2 2.2 1 1 1 2 2 2 0 Papain fold toxin 2 IQCJ-SCHIP1 PF15157.6 EJP66231.1 - 1.5 8.6 4.0 1.8 8.4 4.0 1.1 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif AF-4 PF05110.13 EJP66231.1 - 8.6 4.3 16.2 9.3 4.2 16.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DNA_primase_lrg PF04104.14 EJP66232.1 - 1e-80 271.0 0.0 1.4e-80 270.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit UPA_2 PF17809.1 EJP66232.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 UPA domain WSC PF01822.19 EJP66233.1 - 2.8e-08 33.8 13.9 6.3e-08 32.7 13.9 1.6 1 0 0 1 1 1 1 WSC domain DUF1505 PF07403.11 EJP66233.1 - 0.11 12.6 2.2 0.28 11.4 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Podoplanin PF05808.11 EJP66233.1 - 0.24 11.5 3.2 0.38 10.9 1.9 2.1 2 1 0 2 2 2 0 Podoplanin CoA_trans PF01144.23 EJP66235.1 - 5.1e-96 320.2 0.5 3.5e-55 186.8 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EJP66235.1 - 0.00037 19.0 0.0 0.00056 18.4 0.0 1.1 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 EJP66235.1 - 0.0027 17.6 0.1 0.0053 16.7 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Pkinase PF00069.25 EJP66236.1 - 5.9e-44 150.4 0.0 2.6e-43 148.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66236.1 - 2.1e-28 99.3 0.0 3.2e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP66236.1 - 0.051 12.9 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EJP66236.1 - 0.052 12.3 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EJP66236.1 - 0.15 11.3 0.0 7.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Clr5 PF14420.6 EJP66237.1 - 1.6e-23 82.6 0.5 3.4e-23 81.6 0.5 1.6 1 0 0 1 1 1 1 Clr5 domain Aldedh PF00171.22 EJP66238.1 - 4.3e-72 243.1 0.0 5.3e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ECR1_N PF14382.6 EJP66239.1 - 1.4e-05 24.8 1.7 3.2e-05 23.6 0.4 2.1 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EJP66239.1 - 8.3e-05 22.9 0.1 0.00018 21.8 0.1 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EJP66239.1 - 0.013 16.1 0.5 0.39 11.3 0.1 2.5 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 DUF4536 PF15055.6 EJP66240.1 - 0.00047 20.3 0.1 0.00076 19.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.21 EJP66241.1 - 6e-69 232.3 0.0 7.5e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EJP66241.1 - 0.02 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Acyl_transf_1 PF00698.21 EJP66242.1 - 2.2e-19 70.1 1.7 2.9e-12 46.7 0.1 2.2 1 1 0 2 2 2 2 Acyl transferase domain Sedlin_N PF04628.13 EJP66243.1 - 3.1e-08 33.8 0.0 4.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region HET PF06985.11 EJP66244.1 - 1.7e-23 83.6 0.2 3.4e-23 82.6 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AFG1_ATPase PF03969.16 EJP66245.1 - 3.7e-53 180.7 0.0 5.9e-27 94.5 0.0 4.8 5 0 0 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.6 EJP66245.1 - 2.7e-05 24.6 0.7 0.0048 17.3 0.4 3.2 2 1 0 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 EJP66245.1 - 0.0006 19.7 0.0 0.95 9.3 0.0 2.5 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 EJP66245.1 - 0.00067 19.9 0.0 0.0023 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EJP66245.1 - 0.0038 17.2 0.0 0.0096 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 EJP66245.1 - 0.033 14.1 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EJP66245.1 - 0.048 14.1 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EJP66245.1 - 0.06 12.6 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 EJP66245.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 EJP66245.1 - 0.13 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Nucleoporin_C PF03177.14 EJP66246.1 - 2.4e-172 574.8 7.0 3e-172 574.5 7.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EJP66246.1 - 6.1e-80 269.1 0.0 7.5e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Alfin PF12165.8 EJP66246.1 - 0.088 12.5 0.0 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Alfin eIF-5_eIF-2B PF01873.17 EJP66247.1 - 1.2e-39 134.8 0.1 1.8e-39 134.3 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EJP66247.1 - 0.018 14.6 0.7 0.03 13.8 0.7 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 EJP66247.1 - 0.87 10.0 8.7 0.57 10.5 0.5 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.12 EJP66247.1 - 0.98 9.3 3.2 2.9 7.8 3.3 1.8 1 1 0 1 1 1 0 HypF finger NAT PF04768.13 EJP66248.1 - 2.4e-44 151.0 0.0 4.2e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 EJP66248.1 - 3.1e-31 108.8 0.0 8.1e-30 104.2 0.0 2.2 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 EJP66248.1 - 1.8e-29 102.7 0.0 4.3e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EJP66248.1 - 0.067 13.3 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.21 EJP66249.1 - 2.9e-32 110.3 2.7 3.5e-32 110.0 1.2 1.8 3 0 0 3 3 3 1 Synaptobrevin SNARE PF05739.19 EJP66249.1 - 0.33 11.0 4.7 2 8.5 3.0 2.5 2 0 0 2 2 2 0 SNARE domain NAP PF00956.18 EJP66251.1 - 1.7e-27 96.3 3.8 1.5e-25 89.9 0.4 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) BHD_2 PF10404.9 EJP66251.1 - 0.068 14.1 0.2 0.18 12.8 0.2 1.7 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 GP24_25 PF17388.2 EJP66251.1 - 1.5 8.8 7.5 1 9.4 3.7 2.3 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 CRAL_TRIO PF00650.20 EJP66252.1 - 5.8e-39 133.4 0.0 9.5e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EJP66252.1 - 1.6e-07 31.5 0.0 2.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJP66252.1 - 2.5e-07 30.8 0.1 2.5e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Questin_oxidase PF14027.6 EJP66253.1 - 2.5e-64 218.0 1.8 4e-62 210.7 1.8 2.0 1 1 0 1 1 1 1 Questin oxidase-like XPC-binding PF09280.11 EJP66253.1 - 0.12 12.1 1.0 0.55 10.0 0.3 2.3 2 0 0 2 2 2 0 XPC-binding domain WD40 PF00400.32 EJP66254.1 - 4.2e-39 131.8 30.2 5.4e-07 30.2 0.0 13.4 15 0 0 15 15 15 7 WD domain, G-beta repeat Utp12 PF04003.12 EJP66254.1 - 2.4e-24 85.7 0.0 3.9e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EJP66254.1 - 4.9e-19 68.4 0.0 0.015 15.6 0.0 9.6 4 2 6 11 11 11 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP66254.1 - 4.9e-07 29.0 0.7 0.22 10.4 0.0 5.4 4 3 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EJP66254.1 - 2e-06 27.8 1.5 0.26 11.2 0.1 5.5 5 1 1 6 6 6 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EJP66254.1 - 0.00029 20.3 0.1 4.2 6.6 0.0 4.4 3 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EJP66254.1 - 0.0096 15.3 0.0 1.1 8.6 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain Nup160 PF11715.8 EJP66254.1 - 0.041 12.5 1.3 6.8 5.2 0.0 3.5 3 1 1 4 4 4 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EJP66254.1 - 0.15 11.0 0.1 4.1 6.2 0.0 2.7 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Utp13 PF08625.11 EJP66254.1 - 0.29 11.0 0.6 1.5 8.8 0.2 2.3 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain Septin PF00735.18 EJP66255.1 - 4.6e-115 383.7 0.3 7e-115 383.1 0.3 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EJP66255.1 - 2e-07 31.1 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP66255.1 - 3.9e-06 26.9 1.4 2.2e-05 24.4 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EJP66255.1 - 1.6e-05 24.5 5.0 9.4e-05 22.0 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EJP66255.1 - 0.0015 18.8 0.7 0.0037 17.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 EJP66255.1 - 0.0035 17.5 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 EJP66255.1 - 0.0037 16.8 0.1 0.0078 15.7 0.1 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein AIG1 PF04548.16 EJP66255.1 - 0.0076 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family KAP_NTPase PF07693.14 EJP66255.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 EJP66255.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 EJP66255.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ras PF00071.22 EJP66255.1 - 0.02 14.5 0.6 0.062 12.9 0.5 1.9 2 1 0 2 2 2 0 Ras family AAA_25 PF13481.6 EJP66255.1 - 0.022 14.4 0.1 0.058 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EJP66255.1 - 0.022 15.3 0.3 0.087 13.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EJP66255.1 - 0.027 14.8 1.7 0.063 13.7 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain Casc1_N PF15927.5 EJP66255.1 - 0.04 13.6 9.9 0.1 12.3 9.9 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus NACHT PF05729.12 EJP66255.1 - 0.05 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 EJP66255.1 - 0.065 12.3 0.4 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein FOXP-CC PF16159.5 EJP66255.1 - 0.077 13.6 1.1 0.077 13.6 1.1 2.5 2 1 1 3 3 1 0 FOXP coiled-coil domain Sigma54_activat PF00158.26 EJP66255.1 - 0.097 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EJP66255.1 - 0.13 12.1 0.4 8.3 6.2 0.1 2.7 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EJP66255.1 - 0.13 12.7 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Val_tRNA-synt_C PF10458.9 EJP66255.1 - 0.24 11.7 4.9 0.16 12.3 0.5 2.7 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Dynamin_N PF00350.23 EJP66255.1 - 0.43 10.6 7.0 4.2 7.4 0.1 3.2 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 EJP66255.1 - 1.1 9.9 6.4 7.8 7.1 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e AAA_11 PF13086.6 EJP66255.1 - 4.3 7.0 7.9 21 4.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain Myc-LZ PF02344.15 EJP66255.1 - 7.9 6.7 8.6 3.4 7.9 2.6 2.7 2 0 0 2 2 2 0 Myc leucine zipper domain BCDHK_Adom3 PF10436.9 EJP66256.1 - 6.3e-46 156.2 0.4 1.1e-45 155.4 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EJP66256.1 - 4e-06 27.3 0.0 0.00022 21.7 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.8 EJP66257.1 - 1.5e-84 283.1 0.7 4.9e-83 278.1 0.2 2.8 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EJP66257.1 - 1e-73 247.4 2.6 3.4e-71 239.2 0.2 3.8 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EJP66257.1 - 5.2e-48 163.8 1.1 1.1e-47 162.7 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJP66257.1 - 2.5e-20 73.3 0.0 6.4e-20 72.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EJP66257.1 - 4.4e-10 39.7 0.0 1.5e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 MATH domain YukD PF08817.10 EJP66257.1 - 0.00095 19.8 0.0 2.4 8.9 0.0 3.4 3 0 0 3 3 3 1 WXG100 protein secretion system (Wss), protein YukD Malt_amylase_C PF16657.5 EJP66257.1 - 0.14 12.3 0.1 9 6.5 0.0 2.9 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain PFK PF00365.20 EJP66258.1 - 4.4e-187 620.1 2.1 2.8e-105 351.7 1.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.8 EJP66258.1 - 0.022 14.5 1.0 0.71 9.6 0.0 3.0 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DAGK_cat PF00781.24 EJP66258.1 - 0.043 13.4 0.0 0.44 10.2 0.1 2.7 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain UVR PF02151.19 EJP66258.1 - 0.2 11.5 0.2 0.45 10.3 0.2 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Glyco_hydro_16 PF00722.21 EJP66260.1 - 0.0013 18.3 0.0 0.0037 16.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CshA_NR2 PF18651.1 EJP66260.1 - 0.017 14.3 0.3 0.04 13.1 0.1 1.7 2 0 0 2 2 2 0 Surface adhesin CshA non-repetitive domain 2 Inv-AAD PF18785.1 EJP66260.1 - 0.14 12.1 0.1 0.99 9.3 0.0 2.0 2 0 0 2 2 2 0 Invertebrate-AID/APOBEC-deaminase MT0933_antitox PF14013.6 EJP66261.1 - 0.12 12.7 7.7 0.29 11.5 7.7 1.9 1 1 0 1 1 1 0 MT0933-like antitoxin protein HD PF01966.22 EJP66262.1 - 0.00041 20.6 0.9 0.0011 19.1 0.9 1.8 1 1 0 1 1 1 1 HD domain OHCU_decarbox PF09349.10 EJP66262.1 - 0.049 14.1 0.3 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 OHCU decarboxylase HCV_core PF01542.18 EJP66262.1 - 0.083 13.3 0.2 23 5.5 0.2 2.5 2 0 0 2 2 2 0 Hepatitis C virus core protein Aldedh PF00171.22 EJP66263.1 - 2.2e-16 59.4 16.7 6.6e-10 38.1 12.5 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 EJP66263.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Rep_fac-A_C PF08646.10 EJP66264.1 - 4.8e-55 185.3 5.7 5.5e-54 181.9 3.9 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EJP66264.1 - 3.1e-37 126.4 1.7 1.4e-36 124.3 0.3 2.7 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 EJP66264.1 - 4.4e-21 74.8 0.0 8.8e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EJP66264.1 - 6.4e-15 54.9 0.2 5.3e-11 42.3 0.0 3.6 2 1 1 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EJP66264.1 - 2.1e-05 24.4 0.8 0.00091 19.0 0.3 2.9 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 zf-like PF04071.12 EJP66264.1 - 0.018 14.9 1.4 0.042 13.8 1.4 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain DLH PF01738.18 EJP66265.1 - 7.7e-21 74.6 0.2 3.6e-20 72.5 0.2 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EJP66265.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 EJP66266.1 - 2.1e-26 92.4 0.4 3.6e-26 91.7 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP66266.1 - 1.1e-24 88.0 0.0 1.8e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP66266.1 - 1.4e-08 34.6 0.0 5.2e-08 32.8 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2828 PF11443.8 EJP66266.1 - 0.064 11.3 0.0 0.088 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1510 PF07423.11 EJP66266.1 - 0.12 12.5 0.1 18 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) Fungal_trans PF04082.18 EJP66267.1 - 7.7e-15 54.6 0.1 2e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66267.1 - 3.7e-06 26.9 11.1 8.1e-06 25.9 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.12 EJP66267.1 - 0.79 8.4 3.8 1.4 7.6 3.8 1.2 1 0 0 1 1 1 0 Per os infectivity UNC-93 PF05978.16 EJP66268.1 - 1e-10 41.5 3.4 1e-10 41.5 3.4 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EJP66268.1 - 5.3e-07 28.9 43.3 1.1e-06 27.8 41.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EJP66268.1 - 0.0042 16.0 5.6 0.0093 14.9 5.6 1.6 1 0 0 1 1 1 1 MFS_1 like family DUF2190 PF09956.9 EJP66268.1 - 0.78 10.3 5.7 2 8.9 1.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) Glyco_hydro_56 PF01630.18 EJP66269.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Hyaluronidase AA_permease_2 PF13520.6 EJP66271.1 - 6.8e-49 166.8 50.9 8.6e-49 166.5 50.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP66271.1 - 1.7e-26 92.8 43.1 2.2e-26 92.5 43.1 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.25 EJP66273.1 - 1e-07 32.2 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP66273.1 - 1.9e-07 31.4 0.0 3.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP66273.1 - 3.8e-06 26.8 0.0 7.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP66273.1 - 4.1e-05 23.7 0.0 0.0024 17.9 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP66273.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Glyco_hydro_76 PF03663.14 EJP66274.1 - 2.1e-157 524.3 17.5 2.6e-157 524.1 17.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 YtxH PF12732.7 EJP66274.1 - 0.12 12.9 0.2 0.41 11.2 0.2 1.9 1 0 0 1 1 1 0 YtxH-like protein Glyco_hydro_88 PF07470.13 EJP66274.1 - 1.8 7.5 13.3 0.25 10.4 1.0 3.2 1 1 2 3 3 3 0 Glycosyl Hydrolase Family 88 Metallophos PF00149.28 EJP66275.1 - 6.3e-17 62.8 0.1 1.1e-16 62.0 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP66275.1 - 0.00025 21.3 0.0 0.0039 17.4 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SAP PF02037.27 EJP66276.1 - 8.9e-14 50.9 0.2 1.5e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EJP66276.1 - 1.6e-05 24.6 2.3 1.6e-05 24.6 2.3 1.9 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 EJP66276.1 - 0.14 11.9 0.5 0.32 10.7 0.5 1.6 1 1 0 1 1 1 0 HeH/LEM domain Methyltransf_11 PF08241.12 EJP66277.1 - 0.00011 22.8 0.0 0.00022 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP66277.1 - 0.0017 19.0 0.0 0.0037 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EJP66277.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EJP66277.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3144 PF11342.8 EJP66277.1 - 0.3 11.4 0.5 0.61 10.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) GCD14 PF08704.10 EJP66278.1 - 0.036 13.7 0.0 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.6 EJP66278.1 - 0.039 15.0 0.3 0.11 13.5 0.3 1.8 1 1 0 1 1 1 0 Methyltransferase domain TetR_C_30 PF17939.1 EJP66279.1 - 0.055 13.7 0.5 0.73 10.1 0.1 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Zn_clus PF00172.18 EJP66280.1 - 1.4e-06 28.3 6.3 2.5e-06 27.5 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 EJP66280.1 - 2.1 7.9 14.8 3.4 7.2 14.8 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 EJP66280.1 - 4.9 7.0 23.2 0.42 10.6 16.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TNT PF14021.6 EJP66282.1 - 1.8e-25 89.3 0.0 4.9e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 Tuberculosis necrotizing toxin SapA PF02199.15 EJP66282.1 - 0.049 13.9 4.1 2.1 8.7 0.5 2.5 2 0 0 2 2 2 0 Saposin A-type domain adh_short PF00106.25 EJP66284.1 - 1.2e-14 54.2 0.7 1.5e-14 53.9 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP66284.1 - 7.3e-11 42.1 0.5 8.5e-11 41.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EJP66284.1 - 1.5e-05 24.7 0.3 2.7e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP66284.1 - 7.2e-05 22.8 0.2 0.00017 21.5 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EJP66284.1 - 0.0021 17.6 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP66284.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 EJP66284.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4246 PF14033.6 EJP66285.1 - 7.4e-167 556.0 0.0 7.4e-166 552.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) WD40 PF00400.32 EJP66285.1 - 4.6e-35 119.0 20.0 9.2e-07 29.5 0.5 8.0 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66285.1 - 9.4e-18 64.3 0.0 2.4e-05 24.5 0.0 6.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EJP66285.1 - 0.00019 20.6 0.0 0.00036 19.7 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region PD40 PF07676.12 EJP66285.1 - 0.0002 21.2 0.7 22 5.1 0.0 5.2 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EJP66285.1 - 0.013 14.5 0.0 15 4.4 0.0 4.0 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein 2OG-FeII_Oxy_5 PF13759.6 EJP66285.1 - 0.075 13.5 1.0 0.18 12.2 0.0 2.2 2 0 0 2 2 1 0 Putative 2OG-Fe(II) oxygenase RRN3 PF05327.11 EJP66285.1 - 0.094 11.2 12.1 0.14 10.7 12.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDHD PF02862.17 EJP66285.1 - 0.12 12.6 1.8 0.2 11.8 1.8 1.3 1 0 0 1 1 1 0 DDHD domain Mpp10 PF04006.12 EJP66285.1 - 0.12 10.8 29.4 0.17 10.3 29.4 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF5523 PF17661.1 EJP66285.1 - 0.19 11.4 23.8 0.48 10.1 23.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5523) WD40_like PF17005.5 EJP66285.1 - 0.22 10.8 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain CTU2 PF10288.9 EJP66285.1 - 0.26 11.5 3.7 0.58 10.4 3.7 1.6 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Nop14 PF04147.12 EJP66285.1 - 0.39 8.9 31.7 0.55 8.4 31.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EJP66285.1 - 0.45 9.8 24.8 0.65 9.3 24.8 1.1 1 0 0 1 1 1 0 BUD22 MDM1 PF15501.6 EJP66285.1 - 0.78 8.8 20.7 1.2 8.3 20.7 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 RR_TM4-6 PF06459.12 EJP66285.1 - 0.94 9.2 20.5 1.6 8.5 20.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 EJP66285.1 - 2.5 7.5 16.3 4 6.8 16.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 EJP66285.1 - 2.8 6.1 27.7 4.7 5.4 27.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 EJP66285.1 - 3.4 6.3 12.8 5 5.8 12.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LAP1C PF05609.12 EJP66285.1 - 4.3 6.3 14.8 6.3 5.8 14.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CCSAP PF15748.5 EJP66285.1 - 4.7 7.3 19.9 7.4 6.7 19.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 EJP66285.1 - 6.6 5.4 17.7 9.6 4.9 17.7 1.1 1 0 0 1 1 1 0 Presenilin GPCR_chapero_1 PF11904.8 EJP66285.1 - 7.6 5.9 10.3 12 5.3 10.3 1.2 1 0 0 1 1 1 0 GPCR-chaperone RAB3GAP2_C PF14656.6 EJP66285.1 - 8.7 4.4 6.9 15 3.7 6.9 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RNA_pol_Rpc4 PF05132.14 EJP66285.1 - 9.8 6.6 13.4 18 5.8 13.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1343 PF07075.11 EJP66286.1 - 2.5e-113 379.0 0.0 2.9e-113 378.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) FpoO PF10621.9 EJP66287.1 - 0.014 15.7 0.2 12 6.2 0.0 3.0 3 0 0 3 3 3 0 F420H2 dehydrogenase subunit FpoO UPF0506 PF11703.8 EJP66287.1 - 5.2 7.5 6.4 38 4.8 0.2 3.5 3 0 0 3 3 3 0 UPF0506 Asp PF00026.23 EJP66288.1 - 2.7e-46 158.5 7.5 1.9e-45 155.7 7.5 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EJP66288.1 - 8e-06 26.4 1.3 0.00056 20.5 0.1 2.7 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 EJP66288.1 - 4.5e-05 23.3 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EJP66288.1 - 0.00025 21.6 1.9 0.0096 16.5 0.0 3.2 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 EJP66288.1 - 0.00076 19.8 3.4 0.2 11.9 0.2 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal RasGAP PF00616.19 EJP66289.1 - 0.073 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase BCAS3 PF12490.8 EJP66289.1 - 0.4 10.2 4.1 0.63 9.5 4.1 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 TFB6 PF17110.5 EJP66289.1 - 0.98 9.1 4.8 1.6 8.4 4.8 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RNA_polI_A34 PF08208.11 EJP66289.1 - 2.1 8.4 14.8 3.8 7.6 14.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ATP-synt_E PF05680.12 EJP66289.1 - 6.1 7.3 10.1 16 5.9 10.1 1.6 1 0 0 1 1 1 0 ATP synthase E chain RPN2_C PF18004.1 EJP66289.1 - 8.4 6.3 13.3 13 5.6 13.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain APH PF01636.23 EJP66290.1 - 2.2e-10 40.9 0.5 4.6e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 EJP66290.1 - 0.0042 17.2 9.1 0.012 15.7 9.1 1.8 1 0 0 1 1 1 1 AN1-like Zinc finger Zn_clus PF00172.18 EJP66291.1 - 3.1e-06 27.2 8.9 3.1e-06 27.2 8.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRAL_TRIO PF00650.20 EJP66292.1 - 3.2e-36 124.4 0.0 6.2e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EJP66292.1 - 3.3e-06 27.3 0.0 5.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Adeno_E4 PF05385.11 EJP66292.1 - 0.054 13.6 0.3 0.15 12.2 0.3 1.7 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein CRAL_TRIO_N PF03765.15 EJP66292.1 - 0.068 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain AA_permease_2 PF13520.6 EJP66294.1 - 1.3e-47 162.6 35.3 1.7e-47 162.2 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP66294.1 - 2e-24 86.1 27.1 2.8e-24 85.5 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease YrhK PF14145.6 EJP66295.1 - 0.42 10.5 17.5 1.2 9.1 0.0 4.4 4 1 1 5 5 5 0 YrhK-like protein GrpB PF04229.14 EJP66296.1 - 1.9e-44 151.7 0.0 2.2e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 GrpB protein TRI9 PF08195.11 EJP66296.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 TRI9 protein Bul1_C PF04426.12 EJP66297.1 - 1.7e-05 24.4 0.0 3.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.12 EJP66297.1 - 0.00046 19.1 0.0 0.00078 18.3 0.0 1.4 1 0 0 1 1 1 1 Bul1 N terminus Arrestin_N PF00339.29 EJP66297.1 - 0.0065 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Herpes_capsid PF06112.11 EJP66297.1 - 0.23 11.5 7.0 0.56 10.3 7.0 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SR-25 PF10500.9 EJP66297.1 - 0.47 10.0 9.1 0.77 9.3 9.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 EJP66297.1 - 0.66 10.3 11.6 3.3 8.1 9.1 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF755 PF05501.11 EJP66297.1 - 1 9.7 5.8 2.4 8.5 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) F-box-like PF12937.7 EJP66298.1 - 6e-07 29.3 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP66298.1 - 0.00023 20.9 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain Adeno_terminal PF02459.15 EJP66298.1 - 0.18 10.2 1.0 0.23 9.8 1.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein NTPase_I-T PF01931.18 EJP66301.1 - 0.024 14.4 0.0 0.086 12.6 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF84 DUF2625 PF10946.8 EJP66301.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2625 DUF3020 PF11223.8 EJP66302.1 - 0.43 11.1 2.2 1.4 9.5 2.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) zf-U1 PF06220.12 EJP66303.1 - 1.1e-21 76.3 3.4 1.1e-21 76.3 3.4 1.7 2 0 0 2 2 2 1 U1 zinc finger EMP24_GP25L PF01105.24 EJP66304.1 - 2e-39 135.4 0.0 2.3e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 EJP66304.1 - 0.073 11.2 1.0 0.096 10.8 1.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Nup153 PF08604.10 EJP66305.1 - 0.014 14.2 3.1 0.017 13.9 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup153-like DUF3123 PF11321.8 EJP66305.1 - 0.12 13.1 2.8 0.2 12.4 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Mei4 PF13971.6 EJP66305.1 - 0.21 11.1 0.1 0.27 10.7 0.1 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 IQCJ-SCHIP1 PF15157.6 EJP66305.1 - 0.38 10.6 1.8 0.56 10.0 1.8 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif MGC-24 PF05283.11 EJP66305.1 - 0.45 11.0 14.1 0.82 10.1 13.9 1.6 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CFEM PF05730.11 EJP66305.1 - 0.51 10.5 12.6 0.51 10.5 10.5 2.1 1 1 0 1 1 1 0 CFEM domain Alba PF01918.21 EJP66307.1 - 9.2e-06 25.4 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Alba RNA_pol_3_Rpc31 PF11705.8 EJP66307.1 - 0.00099 19.4 6.1 0.0014 18.9 6.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF1168 PF06658.12 EJP66307.1 - 0.0061 16.4 11.8 0.011 15.6 11.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Pox_Ag35 PF03286.14 EJP66307.1 - 0.085 12.6 6.8 0.15 11.9 6.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spot_14 PF07084.12 EJP66307.1 - 0.16 12.1 2.6 0.23 11.6 2.6 1.2 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 DUF913 PF06025.12 EJP66307.1 - 0.42 9.5 2.0 0.54 9.2 2.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 EJP66307.1 - 0.43 10.0 10.5 0.63 9.4 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PBP_sp32 PF07222.12 EJP66307.1 - 0.58 9.6 9.1 0.85 9.0 9.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TRAP_alpha PF03896.16 EJP66307.1 - 0.68 9.1 5.0 0.86 8.7 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPL5 PF18168.1 EJP66307.1 - 0.96 8.7 5.1 1.3 8.2 5.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 EJP66307.1 - 2.5 6.8 3.5 3.2 6.4 3.5 1.1 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 EJP66307.1 - 4.1 7.3 12.9 8.5 6.3 12.9 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1770 PF08589.10 EJP66307.1 - 8.7 7.4 7.7 0.54 11.3 2.3 1.8 2 0 0 2 2 1 0 Fungal protein of unknown function (DUF1770) ORC_WH_C PF18137.1 EJP66307.1 - 9 6.4 11.9 18 5.4 11.9 1.5 1 1 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF202 PF02656.15 EJP66308.1 - 1.6e-15 57.3 8.7 2.4e-15 56.7 5.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1430 PF07242.11 EJP66308.1 - 0.15 12.4 2.8 1.5 9.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF4231 PF14015.6 EJP66308.1 - 9 6.8 7.8 37 4.9 7.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Tctex-1 PF03645.13 EJP66309.1 - 2.2e-40 137.1 0.0 2.5e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family SPX PF03105.19 EJP66310.1 - 7.4 6.4 14.7 14 5.5 14.7 1.5 1 1 0 1 1 1 0 SPX domain Fringe PF02434.16 EJP66311.1 - 3.4e-05 23.4 0.5 0.00088 18.8 0.5 2.3 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 EJP66311.1 - 0.0012 18.7 0.0 0.045 13.6 0.0 2.2 1 1 1 2 2 2 2 Galactosyltransferase Ceramidase_alk PF04734.13 EJP66312.1 - 8.4e-213 707.6 0.0 9.8e-213 707.4 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EJP66312.1 - 1.1e-51 175.1 0.6 1.8e-51 174.4 0.6 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal SIS PF01380.22 EJP66313.1 - 3.8e-13 49.4 0.1 1.5e-12 47.5 0.0 2.1 2 1 0 2 2 2 1 SIS domain IMUP PF15761.5 EJP66313.1 - 0.02 15.6 8.4 0.27 11.9 2.4 2.7 3 0 0 3 3 3 0 Immortalisation up-regulated protein Phage_Coat_A PF05357.13 EJP66313.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Phage Coat Protein A SPX PF03105.19 EJP66314.1 - 1.6e-09 38.2 11.7 0.00064 19.8 0.3 3.9 2 1 1 4 4 4 3 SPX domain NiFe_hyd_3_EhaA PF17367.2 EJP66314.1 - 0.21 11.7 0.6 0.4 10.9 0.1 1.6 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A RNA_Me_trans PF04252.13 EJP66316.1 - 4.6e-84 281.0 0.0 5.2e-84 280.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 EJP66317.1 - 6.2e-114 381.7 0.0 7.8e-114 381.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 EJP66317.1 - 0.055 12.7 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SKG6 PF08693.10 EJP66317.1 - 8.2 5.9 5.4 16 5.0 5.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CIAPIN1 PF05093.13 EJP66318.1 - 4.5e-41 139.4 2.7 7.2e-41 138.8 2.7 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EJP66318.1 - 2.6e-31 108.6 0.0 3.8e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus zf-CCHC PF00098.23 EJP66319.1 - 3e-59 194.6 85.9 7.1e-07 29.0 3.8 10.3 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.6 EJP66319.1 - 2.7e-12 46.3 72.0 0.00076 19.2 1.1 10.2 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_4 PF14392.6 EJP66319.1 - 1.6e-05 24.5 57.5 0.97 9.2 0.8 10.2 10 0 0 10 10 10 7 Zinc knuckle zf-CCHC_3 PF13917.6 EJP66319.1 - 0.00015 21.6 71.5 0.58 10.2 0.9 10.1 2 2 8 10 10 10 7 Zinc knuckle zf-C2H2_10 PF16588.5 EJP66319.1 - 0.00033 20.3 7.9 0.00068 19.3 1.6 9.0 9 0 0 9 9 9 4 C2H2 zinc-finger zf-CCHC_6 PF15288.6 EJP66319.1 - 0.029 14.2 0.3 0.029 14.2 0.3 10.3 8 1 2 10 10 10 0 Zinc knuckle Aft1_HRR PF11787.8 EJP66320.1 - 1.3e-27 96.7 10.2 1.3e-27 96.7 10.2 4.1 3 2 0 3 3 3 1 Aft1 HRR domain Aft1_HRA PF11786.8 EJP66320.1 - 7.6e-24 83.8 10.5 7.6e-24 83.8 10.5 3.2 4 0 0 4 4 4 1 Aft1 HRA domain Aft1_OSA PF11785.8 EJP66320.1 - 1.2e-21 76.8 9.0 1.2e-21 76.8 9.0 5.1 5 1 0 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 EJP66320.1 - 9.7e-13 48.0 5.8 1.7e-12 47.2 5.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EJP66320.1 - 5.5e-06 26.4 6.0 1.2e-05 25.3 6.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EJP66320.1 - 0.0017 18.8 2.5 0.0017 18.8 2.5 2.3 3 0 0 3 3 3 1 bZIP Maf transcription factor Macoilin PF09726.9 EJP66320.1 - 0.25 9.9 7.0 0.38 9.3 7.0 1.2 1 0 0 1 1 1 0 Macoilin family ZapB PF06005.12 EJP66320.1 - 2.4 8.6 5.7 0.29 11.6 0.3 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 EJP66320.1 - 6.9 6.5 7.3 0.9 9.3 1.0 2.1 2 0 0 2 2 2 0 Septum formation initiator MIS13 PF08202.11 EJP66321.1 - 3.7e-49 167.6 0.1 7.5e-49 166.6 0.1 1.5 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Macoilin PF09726.9 EJP66321.1 - 0.017 13.8 6.7 0.026 13.1 6.7 1.3 1 0 0 1 1 1 0 Macoilin family Sdh5 PF03937.16 EJP66322.1 - 1.7e-23 82.3 0.0 6.8e-23 80.4 0.0 1.9 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase WD40 PF00400.32 EJP66323.1 - 5.9e-30 102.9 25.7 4.1e-06 27.4 0.1 10.4 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66323.1 - 2.7e-17 62.9 5.6 1.4e-05 25.3 0.1 5.2 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EJP66323.1 - 4.9e-05 23.2 1.3 1.3 9.1 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EJP66323.1 - 7.5e-05 21.8 6.0 0.44 9.4 0.1 4.6 6 0 0 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EJP66323.1 - 0.0039 16.6 3.1 0.71 9.2 0.1 4.0 5 0 0 5 5 5 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EJP66323.1 - 0.017 14.4 0.0 0.95 8.7 0.0 2.9 1 1 1 2 2 2 0 WD40-like domain CPSF_A PF03178.15 EJP66323.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 CPSF A subunit region Nup160 PF11715.8 EJP66323.1 - 0.13 10.8 0.1 0.4 9.3 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Glyco_tran_28_C PF04101.16 EJP66324.1 - 2e-20 73.4 0.0 2.6e-19 69.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.9 EJP66325.1 - 7.5e-44 149.2 0.1 1.6e-43 148.2 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Med17 PF10156.9 EJP66327.1 - 4.1e-76 256.5 0.0 5.3e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF4054 PF13262.6 EJP66327.1 - 0.59 10.2 8.1 0.04 13.9 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Ribosomal_60s PF00428.19 EJP66327.1 - 1.1 9.9 14.2 0.13 12.8 5.7 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein SNF2_N PF00176.23 EJP66328.1 - 5.3e-62 209.6 0.2 9.9e-62 208.7 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP66328.1 - 2.4e-13 50.4 0.0 7.7e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EJP66328.1 - 1.1e-06 28.4 6.9 2.2e-06 27.4 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJP66328.1 - 5.2e-06 26.2 1.4 5.2e-06 26.2 1.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EJP66328.1 - 1.5e-05 25.1 0.3 1.5e-05 25.1 0.3 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 EJP66328.1 - 1.8e-05 24.6 4.2 1.8e-05 24.6 4.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EJP66328.1 - 3.4e-05 23.6 10.2 7.2e-05 22.6 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP66328.1 - 0.00058 20.1 10.0 0.0013 19.0 10.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EJP66328.1 - 0.0085 16.0 9.0 0.021 14.8 9.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EJP66328.1 - 0.013 15.6 9.8 0.036 14.2 9.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EJP66328.1 - 5.4 6.9 8.8 58 3.6 9.4 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Phosphodiest PF01663.22 EJP66329.1 - 7.2e-95 318.6 1.2 1.1e-94 318.0 1.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EJP66329.1 - 0.0039 16.6 0.1 0.2 11.0 0.0 2.3 2 0 0 2 2 2 2 Sulfatase PglZ PF08665.12 EJP66329.1 - 0.069 13.2 0.3 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 PglZ domain Haem_oxygenas_2 PF14518.6 EJP66331.1 - 1.5e-41 142.1 1.3 3.3e-41 141.0 1.3 1.6 1 0 0 1 1 1 1 Iron-containing redox enzyme DIOX_N PF14226.6 EJP66332.1 - 8.9e-08 32.9 0.0 1.5e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EJP66332.1 - 4.3e-07 30.4 0.0 8.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MbeB_N PF04837.12 EJP66332.1 - 0.17 12.2 0.3 11 6.5 0.0 2.8 2 1 1 3 3 3 0 MbeB-like, N-term conserved region tRNA-synt_2 PF00152.20 EJP66333.1 - 5.5e-59 199.8 0.0 6.7e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJP66333.1 - 0.068 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EJP66333.1 - 0.19 11.2 0.6 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) AMP-binding PF00501.28 EJP66334.1 - 4.9e-204 677.7 0.0 3.2e-70 236.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EJP66334.1 - 4e-83 279.6 0.0 6.9e-44 150.3 0.0 3.0 2 1 0 2 2 2 2 Condensation domain NAD_binding_4 PF07993.12 EJP66334.1 - 1.5e-40 139.0 0.0 2.5e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EJP66334.1 - 2.6e-30 104.6 6.0 8.1e-11 42.1 0.0 5.1 5 0 0 5 5 5 3 Phosphopantetheine attachment site Epimerase PF01370.21 EJP66334.1 - 1.1e-08 34.9 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EJP66334.1 - 2.6e-05 25.1 0.0 0.13 13.2 0.0 4.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EJP66334.1 - 0.03 13.3 0.8 0.39 9.7 0.4 2.6 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 EJP66335.1 - 1.2e-38 133.0 59.1 2.7e-37 128.5 58.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP66335.1 - 3.9e-14 52.4 15.5 3.9e-14 52.4 15.5 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EJP66335.1 - 5.4e-10 38.3 22.5 7e-10 38.0 22.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EJP66336.1 - 2.3e-27 95.9 12.6 2.8e-24 85.7 12.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily CBM_1 PF00734.18 EJP66337.1 - 5.8e-10 38.9 7.1 5.8e-10 38.9 7.1 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain p450 PF00067.22 EJP66339.1 - 1.6e-60 205.2 0.0 2e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF393 PF04134.12 EJP66340.1 - 0.17 13.2 1.9 94 4.4 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF393 HEAT PF02985.22 EJP66343.1 - 9.4e-15 53.5 16.1 0.0011 19.0 0.0 10.1 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 EJP66343.1 - 1.5e-11 44.6 12.2 1e-07 32.3 0.0 8.2 9 1 1 10 10 7 1 HEAT-like repeat DRIM PF07539.12 EJP66343.1 - 2.5e-08 32.7 1.9 0.018 13.4 0.0 5.0 2 2 2 4 4 4 4 Down-regulated in metastasis HEAT_2 PF13646.6 EJP66343.1 - 9.3e-07 29.2 16.7 0.014 15.8 0.4 7.5 5 2 4 9 9 9 4 HEAT repeats IBN_N PF03810.19 EJP66343.1 - 2.1e-06 27.5 6.5 0.00038 20.3 0.5 5.1 5 0 0 5 5 5 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EJP66343.1 - 3.3e-06 26.8 5.2 0.13 11.8 0.0 4.7 4 2 1 5 5 5 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 EJP66343.1 - 0.00048 20.7 0.5 25 5.6 0.0 6.0 6 2 0 7 7 7 0 Vacuolar 14 Fab1-binding region Arm PF00514.23 EJP66343.1 - 0.00074 19.5 6.4 21 5.4 0.0 6.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 EJP66343.1 - 0.0014 18.6 0.2 1.5 8.7 0.0 4.4 2 2 1 3 3 3 1 Domain of unknown function (DUF3385) HEAT_PBS PF03130.16 EJP66343.1 - 0.019 15.6 0.3 1.2e+02 3.8 0.0 5.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat NUC173 PF08161.12 EJP66343.1 - 0.034 13.8 0.9 5 6.7 0.0 4.2 2 1 1 4 4 4 0 NUC173 domain DUF1548 PF07579.11 EJP66343.1 - 0.11 12.8 1.5 2.4 8.5 0.0 3.2 2 1 2 4 4 4 0 Domain of Unknown Function (DUF1548) Fungal_trans PF04082.18 EJP66344.1 - 8.3e-13 48.0 0.1 1.5e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 EJP66345.1 - 7.4e-39 133.9 0.0 9.2e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EJP66345.1 - 0.028 13.7 0.0 0.055 12.7 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.21 EJP66345.1 - 0.049 12.3 0.0 0.11 11.1 0.1 1.6 2 0 0 2 2 2 0 Aminotransferase class-III Rad21_Rec8_N PF04825.13 EJP66346.1 - 3e-30 104.6 0.0 4.8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EJP66346.1 - 0.00016 20.9 0.0 0.00048 19.4 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein GDI PF00996.18 EJP66347.1 - 6.7e-23 80.9 0.0 9e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor YCII PF03795.14 EJP66347.1 - 0.051 14.0 0.3 4.4 7.8 0.0 2.5 2 0 0 2 2 2 0 YCII-related domain RNase_PH PF01138.21 EJP66348.1 - 1.5e-17 64.3 0.1 4.7e-17 62.7 0.1 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EJP66348.1 - 0.0095 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CIA30 PF08547.12 EJP66349.1 - 1.1e-37 129.5 0.0 1.5e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Ferric_reduct PF01794.19 EJP66350.1 - 1.3e-17 64.1 5.1 1.3e-17 64.1 5.1 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EJP66350.1 - 3e-14 53.4 0.0 2.2e-12 47.4 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EJP66350.1 - 1.5e-12 47.6 0.0 5.2e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EJP66350.1 - 4.3e-05 24.1 0.0 0.012 16.2 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 EJP66350.1 - 0.045 14.3 0.7 0.045 14.3 0.7 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) Glycogen_syn PF05693.13 EJP66351.1 - 0 1165.1 0.0 0 1164.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EJP66351.1 - 1.6e-05 24.5 0.0 0.0067 16.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EJP66351.1 - 4.2e-05 23.6 0.1 0.0001 22.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EJP66351.1 - 7.5e-05 23.2 0.0 0.072 13.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EJP66351.1 - 0.00012 21.8 0.1 0.00026 20.8 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 EJP66351.1 - 0.0034 17.8 0.0 0.0079 16.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Jacalin PF01419.17 EJP66353.1 - 7.5e-07 29.2 0.0 5.2e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Jacalin-like lectin domain AlaDh_PNT_N PF05222.15 EJP66354.1 - 2.1e-21 76.7 0.0 2.9e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EJP66354.1 - 0.086 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_S9 PF00326.21 EJP66355.1 - 6.3e-12 45.4 0.0 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EJP66355.1 - 7.6e-12 45.5 0.0 2.8e-10 40.4 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP66355.1 - 2.6e-06 26.9 0.0 0.038 13.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EJP66355.1 - 0.00091 18.8 0.0 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EJP66355.1 - 0.0018 17.3 0.0 0.0024 16.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 EJP66355.1 - 0.0035 16.8 0.1 0.011 15.3 0.1 1.9 2 1 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 EJP66355.1 - 0.015 15.0 0.1 0.1 12.2 0.0 2.3 2 1 0 2 2 2 0 Putative esterase DUF2920 PF11144.8 EJP66355.1 - 0.21 10.7 0.0 9.8 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) AXE1 PF05448.12 EJP66355.1 - 0.25 10.0 0.0 9.6 4.8 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Clr5 PF14420.6 EJP66356.1 - 3.2e-10 40.1 0.4 5.9e-10 39.2 0.4 1.5 1 0 0 1 1 1 1 Clr5 domain Clr5 PF14420.6 EJP66357.1 - 2.6e-14 53.1 3.1 6.8e-14 51.8 3.1 1.7 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.7 EJP66357.1 - 6.1e-13 49.2 0.7 0.0002 21.9 0.0 3.8 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP66357.1 - 5.7e-11 42.7 3.1 0.00017 22.1 0.0 5.9 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 EJP66357.1 - 6.5e-09 35.8 6.8 0.086 13.3 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EJP66357.1 - 4.1e-08 32.9 3.9 4 8.3 0.1 6.7 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 EJP66357.1 - 1.6e-07 31.5 5.9 9.8e-05 22.6 0.1 3.7 5 0 0 5 5 5 2 Ankyrin repeats (many copies) T3SS_needle_F PF09392.10 EJP66357.1 - 0.04 14.1 0.6 0.14 12.4 0.2 2.1 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF UPRTase PF14681.6 EJP66358.1 - 1e-35 123.1 0.4 2.1e-35 122.1 0.4 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 EJP66358.1 - 3.1e-22 79.5 0.0 1e-21 77.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain HAD PF12710.7 EJP66358.1 - 1.4e-17 64.7 0.0 3.5e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_33 PF13671.6 EJP66358.1 - 2.6e-07 30.9 0.1 8.1e-07 29.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain Hydrolase PF00702.26 EJP66358.1 - 5.9e-05 23.5 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_30 PF13604.6 EJP66358.1 - 0.00024 20.9 1.4 0.52 10.0 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EJP66358.1 - 0.00045 20.5 0.3 0.0067 16.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EJP66358.1 - 0.00048 20.7 0.0 0.0014 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EJP66358.1 - 0.00053 19.3 0.0 0.00085 18.7 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Pribosyltran PF00156.27 EJP66358.1 - 0.00099 18.7 1.0 0.015 14.8 1.0 2.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_16 PF13191.6 EJP66358.1 - 0.0014 19.0 0.0 0.0065 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EJP66358.1 - 0.0018 17.6 0.0 0.0051 16.1 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 EJP66358.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase MeaB PF03308.16 EJP66358.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EJP66358.1 - 0.014 14.6 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 EJP66358.1 - 0.017 15.2 0.1 0.1 12.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase KTI12 PF08433.10 EJP66358.1 - 0.018 14.5 0.0 0.064 12.7 0.0 2.0 1 1 0 1 1 1 0 Chromatin associated protein KTI12 ATPase_2 PF01637.18 EJP66358.1 - 0.037 13.9 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Hydrolase_3 PF08282.12 EJP66358.1 - 0.039 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_24 PF13479.6 EJP66358.1 - 0.04 13.6 0.4 0.47 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EJP66358.1 - 0.054 13.4 0.1 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 EJP66358.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Colicin_Ia PF11504.8 EJP66358.1 - 0.079 13.1 0.1 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Colicin Ia AAA_28 PF13521.6 EJP66358.1 - 0.083 13.1 0.3 0.38 11.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain Fer2_4 PF13510.6 EJP66358.1 - 0.09 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain dNK PF01712.19 EJP66358.1 - 0.11 12.3 0.1 18 5.1 0.0 2.6 3 0 0 3 3 3 0 Deoxynucleoside kinase SKI PF01202.22 EJP66358.1 - 0.12 12.4 0.4 0.4 10.8 0.4 1.9 1 1 0 1 1 1 0 Shikimate kinase RdRP PF05183.12 EJP66359.1 - 2.1e-181 604.6 0.0 2.5e-181 604.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 EJP66359.1 - 0.15 11.9 0.0 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytokin-bind PF09265.10 EJP66359.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding MIF4G_like PF09088.11 EJP66360.1 - 4e-81 271.3 0.0 6.2e-81 270.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EJP66360.1 - 2.5e-71 240.3 0.0 4e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G like DUF4485 PF14846.6 EJP66360.1 - 0.081 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DUF3349 PF11829.8 EJP66360.1 - 0.09 13.6 1.2 30 5.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3349) L51_S25_CI-B8 PF05047.16 EJP66360.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1878 PF08963.10 EJP66360.1 - 0.19 12.2 0.2 0.46 11.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) Pkinase PF00069.25 EJP66361.1 - 3.1e-64 216.9 0.0 3.7e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66361.1 - 3.4e-25 88.8 0.0 4.4e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP66361.1 - 1.7e-06 27.6 0.0 1.1e-05 24.9 0.0 2.0 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EJP66361.1 - 0.0038 17.2 0.0 0.014 15.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1229 PF06797.11 EJP66361.1 - 0.006 16.8 0.2 0.0095 16.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Kdo PF06293.14 EJP66361.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EJP66361.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF272 PF03312.15 EJP66361.1 - 0.16 12.2 0.0 0.71 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF272) 6PF2K PF01591.18 EJP66362.1 - 6.8e-58 195.6 0.0 1.1e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EJP66362.1 - 3.2e-21 75.9 0.7 1.1e-20 74.1 0.7 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EJP66362.1 - 0.0079 16.4 0.0 0.063 13.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EJP66362.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ZnuA PF01297.17 EJP66362.1 - 0.069 12.5 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Porin_3 PF01459.22 EJP66363.1 - 6.1e-81 271.8 0.3 7.1e-81 271.6 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH_1 PF13423.6 EJP66364.1 - 2.8e-34 119.1 0.0 8.9e-33 114.2 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 EJP66364.1 - 9.3e-14 51.5 0.0 3.3e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mucin PF01456.17 EJP66364.1 - 3.5 7.6 16.4 4.6 7.2 1.2 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Ribosomal_L5_C PF00673.21 EJP66365.1 - 1.2e-26 92.7 0.0 2.1e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EJP66365.1 - 1.2e-08 35.1 0.0 2.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.10 EJP66366.1 - 7.9e-31 106.8 3.0 7.9e-31 106.8 3.0 1.9 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 EJP66366.1 - 1.8e-05 25.1 0.7 0.00064 20.2 0.2 3.2 3 1 1 4 4 4 2 HEAT-like repeat Arm PF00514.23 EJP66366.1 - 2.7e-05 24.0 0.1 0.29 11.2 0.1 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EJP66366.1 - 0.0023 18.3 3.1 0.0074 16.7 3.1 1.9 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.22 EJP66366.1 - 0.0045 17.1 0.2 0.053 13.8 0.0 2.6 3 0 0 3 3 3 1 HEAT repeat Actin PF00022.19 EJP66367.1 - 1.4e-150 501.5 0.0 5.3e-150 499.5 0.0 1.7 1 1 0 1 1 1 1 Actin RF-1 PF00472.20 EJP66368.1 - 2.6e-24 85.4 2.8 4.1e-24 84.8 2.8 1.3 1 0 0 1 1 1 1 RF-1 domain HET PF06985.11 EJP66369.1 - 3e-17 63.3 0.1 6.5e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SPT_ssu-like PF11779.8 EJP66370.1 - 1.2e-23 82.5 4.6 1.5e-23 82.2 4.6 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like WD40 PF00400.32 EJP66371.1 - 2.3e-25 88.4 24.1 2.3e-05 25.0 0.0 11.5 13 0 0 13 13 13 7 WD domain, G-beta repeat Mub_B2 PF17966.1 EJP66371.1 - 0.022 15.5 0.1 0.088 13.5 0.1 2.1 1 0 0 1 1 1 0 Mub B2-like domain Urm1 PF09138.11 EJP66372.1 - 3.6e-33 113.8 0.0 4.1e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EJP66372.1 - 5.1e-05 23.8 0.0 6.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 ThiS family zf-C2H2 PF00096.26 EJP66373.1 - 2e-19 68.8 22.0 1.7e-05 25.0 1.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP66373.1 - 2.7e-16 59.2 20.5 1.7e-08 34.5 0.8 4.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP66373.1 - 7.9e-11 41.8 19.5 0.0057 17.4 0.4 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 EJP66373.1 - 0.0016 18.8 9.8 0.06 13.8 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 EJP66373.1 - 0.0099 15.8 6.7 4 7.4 0.2 4.5 4 0 0 4 4 4 2 LYAR-type C2HC zinc finger zf-C2H2_8 PF15909.5 EJP66373.1 - 0.058 13.7 6.4 0.15 12.3 0.7 2.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 EJP66373.1 - 0.18 12.0 4.3 1.2 9.2 0.3 3.3 2 1 0 3 3 3 0 Aberrant zinc-finger DUF3268 PF11672.8 EJP66373.1 - 0.24 11.8 2.4 2.5 8.5 0.2 2.5 2 0 0 2 2 2 0 zinc-finger-containing domain zf-DNA_Pol PF08996.10 EJP66373.1 - 0.39 10.4 7.0 0.26 11.0 1.0 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Mito_carr PF00153.27 EJP66375.1 - 6e-59 196.0 0.2 4.6e-19 68.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.12 EJP66376.1 - 6.1e-19 67.4 0.0 4.9e-15 54.9 0.0 2.0 1 1 1 2 2 2 2 TOM7 family RRM_1 PF00076.22 EJP66377.1 - 1e-32 111.7 0.0 1.5e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJP66377.1 - 0.0005 19.7 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP66377.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif OB_RNB PF08206.11 EJP66377.1 - 0.76 9.5 2.7 19 5.0 0.1 2.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Cohesin_load PF10345.9 EJP66378.1 - 3.9e-113 379.0 0.1 3.9e-113 379.0 0.1 2.3 2 0 0 2 2 2 1 Cohesin loading factor Transglut_core PF01841.19 EJP66379.1 - 2.2e-12 47.4 0.2 5.8e-12 46.1 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EJP66379.1 - 1.7e-05 24.4 0.1 4.1e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EJP66379.1 - 0.0088 15.6 0.1 0.0088 15.6 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EJP66379.1 - 0.027 14.3 0.1 0.078 12.9 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.25 EJP66380.1 - 2.8e-62 210.5 0.0 4e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66380.1 - 4.7e-44 150.6 0.0 7.7e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP66380.1 - 2.6e-06 26.5 0.0 4.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EJP66380.1 - 2.4e-05 23.8 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJP66380.1 - 0.043 13.2 0.2 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_UL49_2 PF04823.12 EJP66380.1 - 0.12 12.4 0.3 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein RAI1 PF08652.11 EJP66381.1 - 9.2e-26 89.8 0.0 1.8e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Ribosomal_S6e PF01092.19 EJP66381.1 - 0.037 14.0 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S6e HDA2-3 PF11496.8 EJP66382.1 - 0.04 13.1 5.4 0.042 13.0 0.0 2.7 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 BRE1 PF08647.11 EJP66382.1 - 7.8 6.6 30.8 2.1 8.5 13.6 3.9 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase COX5A PF02284.16 EJP66383.1 - 1.3e-41 140.8 0.1 2e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF3144 PF11342.8 EJP66383.1 - 0.0055 17.0 4.1 0.55 10.6 1.6 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3144) ELO PF01151.18 EJP66384.1 - 1.4e-62 211.5 17.5 1.7e-62 211.2 17.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family IU_nuc_hydro PF01156.19 EJP66384.1 - 0.044 13.3 0.0 0.053 13.1 0.0 1.1 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase F-box-like PF12937.7 EJP66385.1 - 8.4e-06 25.6 0.8 1.8e-05 24.5 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP66385.1 - 0.082 12.8 0.4 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 F-box domain DUF4106 PF13388.6 EJP66386.1 - 1.2 8.3 9.5 2.4 7.3 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Aminotran_1_2 PF00155.21 EJP66387.1 - 3.7e-11 42.8 0.0 2.5e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Ribosomal_L4 PF00573.22 EJP66388.1 - 2.6e-37 128.4 0.1 3.7e-37 127.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EJP66388.1 - 4.7e-28 97.1 2.0 4.7e-28 97.1 2.0 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DEAD PF00270.29 EJP66389.1 - 2.9e-43 147.7 0.0 4.3e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP66389.1 - 5.6e-28 97.5 0.6 3.1e-27 95.1 0.5 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP66389.1 - 0.00031 20.8 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EJP66389.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit API5 PF05918.11 EJP66389.1 - 2.3 6.9 7.1 3.7 6.3 7.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Acyl-CoA_dh_1 PF00441.24 EJP66390.1 - 1.1e-40 139.2 0.2 1.6e-40 138.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EJP66390.1 - 5.6e-21 74.6 0.2 1e-20 73.7 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EJP66390.1 - 6e-21 75.2 0.0 1.2e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 EJP66390.1 - 9.1e-18 64.2 0.6 1.9e-17 63.1 0.6 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 EJP66390.1 - 1e-07 32.3 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 EJP66390.1 - 0.11 13.0 0.1 1.1 9.8 0.0 2.5 2 1 1 3 3 3 0 C6 domain XPG_I PF00867.18 EJP66391.1 - 6e-32 109.9 1.5 1.2e-31 108.9 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EJP66391.1 - 2.1e-31 108.4 0.0 2.1e-31 108.4 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EJP66391.1 - 6e-06 26.8 0.8 2.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 EJP66391.1 - 0.025 14.7 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EJP66391.1 - 0.078 13.6 0.0 0.23 12.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain GN3L_Grn1 PF08701.11 EJP66391.1 - 0.32 11.1 0.1 0.32 11.1 0.1 3.4 3 1 1 4 4 4 0 GNL3L/Grn1 putative GTPase WSC PF01822.19 EJP66394.1 - 9.4e-12 45.0 7.4 9.4e-12 45.0 7.4 1.8 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 EJP66394.1 - 9.6e-10 37.7 8.1 9.6e-10 37.7 8.1 2.1 2 0 0 2 2 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 EJP66394.1 - 0.00028 21.0 0.9 0.00048 20.3 0.9 1.3 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.11 EJP66394.1 - 0.0067 16.9 2.9 0.017 15.6 2.9 1.6 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 EJP66394.1 - 0.0077 16.1 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family DctM PF06808.12 EJP66394.1 - 0.016 14.1 0.5 0.025 13.4 0.5 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component Alpha_GJ PF03229.13 EJP66394.1 - 0.02 15.5 4.2 0.02 15.5 4.2 1.9 2 1 0 2 2 2 0 Alphavirus glycoprotein J Amnionless PF14828.6 EJP66394.1 - 0.027 13.3 0.1 0.041 12.7 0.1 1.2 1 0 0 1 1 1 0 Amnionless Insulin_TMD PF17870.1 EJP66394.1 - 0.04 14.0 0.3 0.08 13.0 0.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5305 PF17231.2 EJP66394.1 - 0.04 13.3 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 EJP66394.1 - 0.043 14.7 0.0 0.095 13.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EJP66394.1 - 0.058 13.3 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Nitrate_red_gam PF02665.14 EJP66394.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF4448 PF14610.6 EJP66394.1 - 0.078 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3042 PF11240.8 EJP66394.1 - 0.12 12.4 1.0 0.33 11.0 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF1180 PF06679.12 EJP66394.1 - 3.1 8.2 5.8 0.59 10.5 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Asp PF00026.23 EJP66395.1 - 6.9e-108 360.8 0.0 8.2e-108 360.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP66395.1 - 5.7e-16 59.3 4.1 5.4e-14 52.8 2.4 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP66395.1 - 2e-05 25.2 0.1 0.13 12.9 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EJP66395.1 - 0.0015 18.3 0.0 0.019 14.8 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EJP66395.1 - 0.003 18.1 0.0 1.5 9.4 0.0 2.9 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease BDHCT_assoc PF16204.5 EJP66395.1 - 0.04 13.6 0.2 0.061 13.0 0.2 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Alpha-amylase_C PF02806.18 EJP66395.1 - 0.14 12.6 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain LacI PF00356.21 EJP66396.1 - 0.025 14.3 0.3 0.097 12.5 0.3 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF155 PF02582.14 EJP66397.1 - 9.7e-45 152.8 0.0 1.3e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CRAL_TRIO PF00650.20 EJP66398.1 - 1.3e-36 125.8 0.0 2e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJP66398.1 - 1.2e-06 28.5 0.1 5.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EJP66398.1 - 0.0022 18.2 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EJP66398.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Mis14 PF08641.12 EJP66399.1 - 9.7e-13 48.6 0.1 2.3e-12 47.3 0.1 1.7 1 1 0 1 1 1 1 Kinetochore protein Mis14 like MFS_1 PF07690.16 EJP66403.1 - 1.3e-27 96.7 34.0 2e-27 96.1 34.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0114 PF03350.16 EJP66403.1 - 1.5 9.1 6.7 0.23 11.7 0.3 2.6 3 0 0 3 3 3 0 Uncharacterized protein family, UPF0114 AAA PF00004.29 EJP66404.1 - 1.8e-45 154.6 1.1 6.6e-45 152.8 0.0 2.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EJP66404.1 - 9.6e-11 41.5 0.0 6.4e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EJP66404.1 - 7.9e-09 35.6 0.3 3.1e-08 33.7 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJP66404.1 - 6.5e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EJP66404.1 - 2e-07 31.5 0.6 3.5e-05 24.3 0.0 3.1 2 2 2 4 4 4 1 AAA ATPase domain DUF815 PF05673.13 EJP66404.1 - 4.8e-06 25.9 0.0 1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EJP66404.1 - 4.7e-05 23.7 1.4 0.0081 16.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EJP66404.1 - 0.0003 20.5 0.0 0.00091 19.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EJP66404.1 - 0.00031 20.5 0.0 0.00071 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 EJP66404.1 - 0.00053 20.5 0.0 0.0016 19.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 EJP66404.1 - 0.0008 19.8 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 EJP66404.1 - 0.00099 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EJP66404.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 EJP66404.1 - 0.0015 18.5 0.0 0.022 14.7 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EJP66404.1 - 0.0018 17.8 0.1 0.0096 15.4 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EJP66404.1 - 0.0024 17.9 0.1 0.0069 16.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 EJP66404.1 - 0.0027 17.6 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 EJP66404.1 - 0.0034 17.3 0.4 0.11 12.4 0.0 3.1 4 0 0 4 4 4 1 NACHT domain AAA_30 PF13604.6 EJP66404.1 - 0.0054 16.5 1.5 0.013 15.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EJP66404.1 - 0.0065 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EJP66404.1 - 0.0081 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EJP66404.1 - 0.0083 16.3 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EJP66404.1 - 0.0087 15.5 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AFG1_ATPase PF03969.16 EJP66404.1 - 0.015 14.2 0.1 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase IstB_IS21 PF01695.17 EJP66404.1 - 0.015 15.0 0.2 0.044 13.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 EJP66404.1 - 0.016 15.0 0.2 0.046 13.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain Viral_Hsp90 PF03225.14 EJP66404.1 - 0.024 13.2 0.0 0.038 12.5 0.0 1.3 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue ATPase PF06745.13 EJP66404.1 - 0.035 13.5 1.3 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 EJP66404.1 - 0.037 13.9 0.9 0.21 11.5 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EJP66404.1 - 0.04 13.7 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EJP66404.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.6 EJP66404.1 - 0.073 13.6 0.4 5.4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EJP66404.1 - 0.08 12.6 0.2 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 EJP66404.1 - 0.096 12.3 1.4 0.27 10.8 0.1 2.2 2 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EJP66404.1 - 0.14 12.5 0.1 0.41 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJP66404.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 EJP66404.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Folliculin PF11704.8 EJP66405.1 - 6.5e-57 192.4 0.0 1.2e-56 191.6 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DNA_methylase PF00145.17 EJP66406.1 - 1.2e-35 123.5 0.0 3.1e-35 122.1 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Drc1-Sld2 PF11719.8 EJP66407.1 - 5.3e-82 276.8 11.3 6.2e-82 276.5 11.3 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein WD40 PF00400.32 EJP66408.1 - 7.9e-54 178.4 34.1 1.3e-07 32.2 0.1 13.1 14 0 0 14 14 14 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66408.1 - 9e-21 74.0 0.2 0.01 16.1 0.0 10.0 7 3 3 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP66408.1 - 6.9e-14 51.5 5.5 0.2 10.6 0.0 8.2 6 2 4 10 10 10 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 EJP66408.1 - 1.6e-06 28.2 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Proteasome_A_N PF10584.9 EJP66408.1 - 4.9e-06 26.1 1.8 14 5.4 0.0 5.5 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature PD40 PF07676.12 EJP66408.1 - 5.3e-06 26.2 0.6 12 6.0 0.0 6.5 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EJP66408.1 - 0.0011 17.7 2.0 1.1 7.8 0.1 4.5 6 0 0 6 6 6 2 Nucleoporin Nup120/160 AAA_16 PF13191.6 EJP66408.1 - 0.014 15.8 0.1 0.056 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EJP66408.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EJP66408.1 - 0.16 12.3 0.0 0.5 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NUDIX PF00293.28 EJP66409.1 - 6.7e-17 61.8 0.0 1.3e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 EJP66410.1 - 2.1e-05 24.6 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_1 PF00561.20 EJP66412.1 - 8.4e-46 156.7 0.0 2.5e-45 155.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EJP66412.1 - 0.00036 20.3 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF2048 PF09752.9 EJP66412.1 - 0.083 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Hydrolase_4 PF12146.8 EJP66412.1 - 0.12 11.6 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Isy1 PF06246.12 EJP66414.1 - 4.7e-88 295.0 0.3 5.5e-88 294.8 0.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 EJP66414.1 - 0.017 15.1 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 YolD-like protein DDOST_48kD PF03345.14 EJP66415.1 - 1.1e-157 525.1 0.0 1.3e-157 524.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Beach PF02138.18 EJP66417.1 - 1.7e-120 401.5 0.0 4.4e-120 400.2 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EJP66417.1 - 1.1e-09 38.2 0.0 4.3e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EJP66417.1 - 8.4e-08 32.5 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 EJP66417.1 - 0.00016 21.1 0.1 0.00065 19.0 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) WD40 PF00400.32 EJP66417.1 - 0.00021 22.0 3.0 8.7 7.4 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4800 PF16057.5 EJP66417.1 - 0.21 10.9 3.7 1 8.6 3.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4800) Peptidase_S8 PF00082.22 EJP66418.1 - 5.7e-35 121.0 6.0 9.9e-35 120.2 6.0 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJP66418.1 - 3.7e-20 72.4 0.8 1.2e-19 70.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase inhibitor I9 PAF-AH_p_II PF03403.13 EJP66420.1 - 7.4e-30 103.7 0.0 2.6e-29 101.9 0.0 1.6 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EJP66420.1 - 0.00018 20.5 0.0 0.032 13.1 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EJP66420.1 - 0.0023 17.3 0.2 0.11 11.7 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EJP66420.1 - 0.042 12.9 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase ECH_1 PF00378.20 EJP66421.1 - 8.5e-36 123.5 0.4 1.4e-35 122.8 0.4 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP66421.1 - 1e-25 91.0 0.1 1.6e-22 80.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Tfb5 PF06331.12 EJP66422.1 - 1.1e-24 86.2 0.7 1.1e-24 86.1 0.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 TFIIF_alpha PF05793.12 EJP66423.1 - 0.035 12.7 12.6 0.046 12.3 12.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UL42 PF17638.2 EJP66423.1 - 0.9 9.5 13.4 0.37 10.8 7.6 2.9 3 0 0 3 3 3 0 HCMV UL42 TMEM154 PF15102.6 EJP66423.1 - 1.6 8.6 0.0 1.6 8.6 0.0 3.2 3 1 0 3 3 3 0 TMEM154 protein family SOG2 PF10428.9 EJP66423.1 - 4.1 6.5 17.9 6.3 5.9 17.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein ER_lumen_recept PF00810.18 EJP66424.1 - 6.8e-43 147.0 8.6 9.4e-43 146.6 8.6 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF1516 PF07457.11 EJP66424.1 - 0.024 14.8 0.5 0.048 13.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) DUF2423 PF10338.9 EJP66425.1 - 1.1 9.6 7.7 36 4.7 0.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2423) CS PF04969.16 EJP66426.1 - 1.7e-16 60.9 0.8 2.7e-16 60.3 0.0 1.7 3 0 0 3 3 3 1 CS domain MAT1 PF06391.13 EJP66427.1 - 7.9e-33 114.0 0.2 9.2e-33 113.8 0.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EJP66427.1 - 4.1e-30 103.4 9.0 6.4e-30 102.8 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP66427.1 - 2.7e-05 23.9 6.5 5.2e-05 23.0 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.6 EJP66427.1 - 0.00021 21.3 6.5 0.00031 20.7 6.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 zf-C3HC4_3 PF13920.6 EJP66427.1 - 0.00042 20.1 6.5 0.00077 19.3 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP66427.1 - 0.0033 17.7 6.4 0.0063 16.8 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain DUF3797 PF12677.7 EJP66427.1 - 0.0082 16.0 3.4 0.019 14.8 3.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3797) zf-C3HC4_2 PF13923.6 EJP66427.1 - 0.022 14.6 8.6 0.1 12.5 8.7 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EJP66427.1 - 0.04 14.0 3.4 0.077 13.2 3.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-piccolo PF05715.13 EJP66427.1 - 0.077 13.2 2.6 0.16 12.1 2.6 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_4 PF14570.6 EJP66427.1 - 0.18 11.6 11.2 1.4 8.8 11.5 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EJP66427.1 - 0.22 11.5 10.2 0.78 9.8 10.4 1.8 1 1 1 2 2 2 0 zinc-RING finger domain CorA PF01544.18 EJP66427.1 - 0.55 9.5 2.6 0.73 9.1 2.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-RING_UBOX PF13445.6 EJP66427.1 - 1.2 9.2 6.0 2.3 8.3 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-UDP PF14569.6 EJP66427.1 - 2.1 8.5 8.4 20 5.4 8.6 2.1 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 EJP66427.1 - 2.2 8.5 6.8 4.5 7.5 6.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EJP66427.1 - 5.3 7.0 7.8 12 5.9 2.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 eIF3_subunit PF08597.10 EJP66427.1 - 5.9 6.7 17.3 5 7.0 15.8 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit ANTH PF07651.16 EJP66428.1 - 3.3e-61 206.7 0.0 4.2e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EJP66428.1 - 1.3e-06 28.4 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.20 EJP66429.1 - 3.5e-77 259.6 0.0 4.5e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EJP66429.1 - 0.036 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) p450 PF00067.22 EJP66430.1 - 8.8e-57 192.9 0.0 1.1e-56 192.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EJP66431.1 - 5.8e-42 143.9 61.5 5.7e-40 137.3 62.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP66431.1 - 7.8e-17 60.9 21.5 1.3e-16 60.2 21.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EJP66431.1 - 8.6e-17 61.1 15.3 8.6e-17 61.1 15.3 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3806 PF12713.7 EJP66431.1 - 0.17 11.7 0.0 7.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) DUF829 PF05705.14 EJP66432.1 - 3.1e-51 174.6 0.0 3.6e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Chal_sti_synt_C PF02797.15 EJP66433.1 - 1e-21 77.5 0.0 1.7e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EJP66433.1 - 3.2e-17 62.7 0.1 4.4e-17 62.3 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.10 EJP66433.1 - 5.5e-07 29.7 0.0 1.9e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PS-DH PF14765.6 EJP66434.1 - 1.7e-68 231.0 0.1 2.8e-68 230.3 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EJP66434.1 - 1e-62 212.0 0.0 2.1e-62 211.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EJP66434.1 - 3.7e-57 193.1 0.4 8.1e-57 192.0 0.4 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EJP66434.1 - 7.6e-55 186.6 0.0 1.3e-54 185.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP66434.1 - 3.5e-31 107.7 0.9 3.5e-31 107.7 0.9 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EJP66434.1 - 1.1e-24 87.0 0.0 2.4e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EJP66434.1 - 4.5e-21 75.4 0.0 1.2e-20 74.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EJP66434.1 - 5.2e-16 58.8 0.1 1.8e-15 57.1 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP66434.1 - 1.8e-14 54.9 0.0 4e-13 50.6 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EJP66434.1 - 4.4e-13 49.4 0.0 9.2e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP66434.1 - 6.4e-13 49.2 0.1 2.8e-11 44.0 0.0 3.4 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP66434.1 - 2.7e-11 43.5 0.0 6.2e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP66434.1 - 1.2e-10 41.9 0.0 1.1e-09 38.8 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain adh_short PF00106.25 EJP66434.1 - 1.6e-10 40.8 0.5 2.1e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 EJP66434.1 - 6e-08 32.5 0.3 2.4e-07 30.6 0.3 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EJP66434.1 - 2.8e-07 30.8 0.0 8.8e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 EJP66434.1 - 1e-06 28.5 0.1 2.4e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NodS PF05401.11 EJP66434.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Thiolase_N PF00108.23 EJP66434.1 - 0.0023 17.3 0.3 0.0091 15.4 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EJP66434.1 - 0.0036 16.7 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CoA_trans PF01144.23 EJP66434.1 - 0.022 14.1 0.0 2.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Coenzyme A transferase Methyltransf_16 PF10294.9 EJP66434.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Lysine methyltransferase DREV PF05219.12 EJP66434.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 EJP66434.1 - 0.078 12.7 0.1 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NAD_binding_10 PF13460.6 EJP66434.1 - 0.15 11.9 0.7 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding ACP_syn_III_C PF08541.10 EJP66434.1 - 0.39 10.9 4.4 0.86 9.8 0.9 3.2 2 1 1 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Zn_clus PF00172.18 EJP66435.1 - 5.8e-06 26.3 8.6 1.4e-05 25.1 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4611 PF15387.6 EJP66435.1 - 0.02 15.1 1.6 0.19 12.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) V-ATPase_H_N PF03224.14 EJP66435.1 - 0.057 12.7 0.1 0.083 12.2 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Paired_CXXCH_1 PF09699.10 EJP66435.1 - 0.36 10.6 5.0 1.8 8.4 0.1 3.1 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) Coatomer_WDAD PF04053.14 EJP66437.1 - 0.0028 16.8 0.1 0.0032 16.6 0.1 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Utp11 PF03998.13 EJP66438.1 - 7.2e-63 212.8 25.0 8.1e-63 212.6 25.0 1.0 1 0 0 1 1 1 1 Utp11 protein FlxA PF14282.6 EJP66438.1 - 1.6 8.8 11.3 0.24 11.4 2.3 3.0 3 1 0 3 3 3 0 FlxA-like protein DUF501 PF04417.12 EJP66438.1 - 2.5 7.9 0.0 2.5 7.9 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF501) Med9 PF07544.13 EJP66438.1 - 4.2 7.5 12.3 0.11 12.6 4.1 2.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 RR_TM4-6 PF06459.12 EJP66438.1 - 4.6 7.0 14.6 0.8 9.5 9.9 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PDDEXK_6 PF04720.12 EJP66438.1 - 7.8 6.4 11.5 0.77 9.7 6.7 1.7 2 0 0 2 2 2 0 PDDEXK-like family of unknown function RNA_pol_Rpb1_7 PF04990.12 EJP66439.1 - 0.56 10.2 3.3 7.4 6.6 0.0 3.0 3 1 0 3 3 3 0 RNA polymerase Rpb1, domain 7 AFT PF08731.11 EJP66439.1 - 4 7.9 6.7 0.85 10.0 2.0 2.2 2 0 0 2 2 2 0 Transcription factor AFT Cmc1 PF08583.10 EJP66440.1 - 3.1e-15 56.0 3.3 4.9e-15 55.3 3.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 EJP66440.1 - 0.022 14.9 2.0 3.6 7.8 0.2 2.3 2 0 0 2 2 2 0 CHCH domain DUF3128 PF11326.8 EJP66440.1 - 0.46 10.9 5.5 26 5.3 5.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) MARVEL PF01284.23 EJP66441.1 - 5.8e-08 32.9 13.6 1e-07 32.1 13.6 1.4 1 0 0 1 1 1 1 Membrane-associating domain Syndecan PF01034.20 EJP66441.1 - 0.015 15.2 0.6 0.059 13.3 0.0 2.3 2 0 0 2 2 2 0 Syndecan domain DUF4834 PF16118.5 EJP66441.1 - 0.31 12.0 0.0 0.31 12.0 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) ADH_N PF08240.12 EJP66442.1 - 4.3e-28 97.4 1.2 4.3e-28 97.4 1.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP66442.1 - 1.3e-23 83.4 0.5 2.3e-23 82.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EJP66442.1 - 7.3e-10 38.7 0.5 1.3e-09 37.8 0.5 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EJP66442.1 - 6.3e-07 30.5 0.1 2.2e-06 28.8 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EJP66442.1 - 0.0013 18.1 1.4 0.002 17.5 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EJP66442.1 - 0.0065 16.1 0.2 0.015 14.8 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 EJP66442.1 - 0.0073 15.6 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP66442.1 - 0.015 14.0 0.4 0.026 13.2 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Prot_ATP_ID_OB PF16450.5 EJP66442.1 - 0.019 14.9 0.7 0.2 11.6 0.1 2.6 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Methyltransf_25 PF13649.6 EJP66442.1 - 0.092 13.5 0.1 0.23 12.2 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EJP66442.1 - 0.18 11.6 0.0 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 EJP66442.1 - 0.33 11.0 1.7 0.85 9.7 0.7 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ECH_1 PF00378.20 EJP66443.1 - 2.8e-38 131.7 0.0 1.1e-36 126.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP66443.1 - 1.3e-19 70.9 0.0 1.6e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MoCF_biosynth PF00994.24 EJP66445.1 - 8.3e-25 87.1 0.1 2.2e-13 50.1 0.1 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain DUF1674 PF07896.12 EJP66446.1 - 3.6e-16 59.4 3.2 9.9e-16 58.0 3.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Ras PF00071.22 EJP66447.1 - 1.1e-53 181.1 1.3 4.8e-52 175.8 1.3 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EJP66447.1 - 9.6e-18 64.5 0.1 2.5e-15 56.7 0.1 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EJP66447.1 - 3.8e-08 33.1 0.0 5.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EJP66447.1 - 1.7e-06 27.6 0.1 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EJP66447.1 - 0.0014 18.6 0.0 1.5 8.7 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EJP66447.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EJP66447.1 - 0.024 14.7 0.0 0.086 12.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EJP66447.1 - 0.093 12.5 0.2 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EJP66447.1 - 0.12 11.9 0.0 0.92 9.0 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B Trypsin_2 PF13365.6 EJP66449.1 - 8.1e-09 36.5 0.2 1.2e-08 36.0 0.2 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EJP66449.1 - 5.9e-07 29.5 0.0 9.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP66450.1 - 1.6e-08 35.6 0.0 3.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EJP66450.1 - 1.5e-07 31.5 0.0 4.8e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 EJP66450.1 - 0.0013 17.4 0.3 0.0077 14.9 0.0 2.3 3 0 0 3 3 3 1 Peptidase S46 Abhydrolase_2 PF02230.16 EJP66451.1 - 7.6e-19 68.4 0.0 8.9e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EJP66451.1 - 0.0078 15.7 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EJP66451.1 - 0.078 13.6 12.4 0.3 11.7 12.4 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.14 EJP66451.1 - 0.088 12.1 0.0 0.55 9.5 0.0 2.1 2 1 1 3 3 3 0 Secretory lipase Abhydrolase_3 PF07859.13 EJP66451.1 - 0.16 11.8 0.1 5.9 6.7 0.1 2.7 2 1 1 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EJP66452.1 - 1.4e-20 74.0 1.0 2.2e-20 73.4 1.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP66452.1 - 7.9e-08 31.6 0.0 1.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Zn_clus PF00172.18 EJP66453.1 - 3.5e-09 36.6 9.8 7.7e-09 35.5 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP66453.1 - 1.3e-05 24.4 0.1 2.6e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EJP66454.1 - 2.5e-29 102.3 60.8 9.3e-16 57.7 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EJP66454.1 - 0.37 9.6 17.3 0.066 12.1 13.2 1.6 1 1 1 2 2 2 0 MFS_1 like family Acetyltransf_1 PF00583.25 EJP66455.1 - 0.0068 16.6 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Xpo1 PF08389.12 EJP66456.1 - 7.1e-27 94.3 4.6 7.6e-26 91.0 0.1 4.3 4 1 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 EJP66456.1 - 1.1e-06 28.5 0.0 0.00015 21.6 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF29 PF01724.16 EJP66456.1 - 0.035 14.3 0.1 17 5.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function DUF29 Tab2_like PF06485.11 EJP66456.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Adaptin_N PF01602.20 EJP66456.1 - 0.044 12.3 1.1 3.1 6.3 0.0 3.0 2 1 1 3 3 3 0 Adaptin N terminal region Importin_rep_3 PF18806.1 EJP66456.1 - 0.046 13.8 0.5 0.54 10.3 0.0 3.0 3 0 0 3 3 3 0 Importin 13 repeat FAM178 PF14816.6 EJP66456.1 - 0.056 12.4 0.0 0.16 10.9 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function, FAM178 GAT PF03127.14 EJP66456.1 - 0.097 13.0 1.7 2 8.8 0.2 2.8 2 0 0 2 2 2 0 GAT domain 5-FTHF_cyc-lig PF01812.20 EJP66457.1 - 8e-32 110.6 0.0 1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.15 EJP66458.1 - 1e-203 678.4 33.9 1.2e-203 678.2 33.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1453 PF07301.11 EJP66458.1 - 0.027 14.5 0.5 0.027 14.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) RPN1_RPN2_N PF17781.1 EJP66459.1 - 1.1e-114 383.0 4.6 3.1e-114 381.6 5.0 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EJP66459.1 - 2.3e-29 101.2 0.0 3.9e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EJP66459.1 - 1.1e-21 76.1 14.4 1.1e-06 28.7 0.1 8.5 8 1 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EJP66459.1 - 1.1e-09 38.5 0.4 0.00061 20.1 0.0 4.1 4 1 1 5 5 5 2 HEAT repeats AbbA_antirepres PF14156.6 EJP66459.1 - 0.013 15.3 0.0 8.9 6.3 0.0 3.2 2 0 0 2 2 2 0 Antirepressor AbbA HEAT PF02985.22 EJP66459.1 - 0.021 15.0 0.1 27 5.4 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Tropomyosin_1 PF12718.7 EJP66459.1 - 0.13 12.4 6.0 0.31 11.2 6.0 1.5 1 0 0 1 1 1 0 Tropomyosin like RIO1 PF01163.22 EJP66460.1 - 4.1e-40 137.4 0.1 1.9e-39 135.2 0.1 1.9 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EJP66460.1 - 2e-31 108.0 0.0 4e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EJP66460.1 - 1.9e-07 31.2 1.2 0.0024 17.8 0.1 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EJP66460.1 - 2.9e-06 26.8 0.2 0.00015 21.2 0.1 2.6 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RXT2_N PF08595.11 EJP66460.1 - 0.32 11.0 2.8 0.62 10.1 2.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EJP66460.1 - 9.2 5.5 8.4 14 4.9 8.4 1.1 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 EJP66461.1 - 1.3e-20 73.0 0.0 1.8e-09 37.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 EJP66462.1 - 7.1e-60 202.3 0.0 1.4e-59 201.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EJP66462.1 - 2.5e-34 118.5 0.7 5.1e-34 117.5 0.7 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EJP66462.1 - 3.8e-20 72.5 0.0 1.9e-19 70.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EJP66462.1 - 0.11 12.8 0.0 0.38 11.0 0.0 2.0 1 0 0 1 1 1 0 Flavodoxin domain Amidase PF01425.21 EJP66463.1 - 2.7e-69 234.3 0.0 3.8e-68 230.5 0.0 2.0 1 1 0 1 1 1 1 Amidase Adenylsucc_synt PF00709.21 EJP66464.1 - 4.7e-165 549.6 0.0 5.3e-165 549.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Apolipoprotein PF01442.18 EJP66466.1 - 0.00077 19.4 12.8 0.022 14.7 7.1 3.1 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain LacI PF00356.21 EJP66466.1 - 0.089 12.6 0.1 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Phage_mat-A PF03863.13 EJP66466.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Phage maturation protein ApoO PF09769.9 EJP66466.1 - 0.29 11.1 1.3 31 4.5 0.0 3.1 3 0 0 3 3 3 0 Apolipoprotein O Phasin PF05597.11 EJP66466.1 - 0.58 10.2 0.0 0.58 10.2 0.0 4.6 2 1 2 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AAA PF00004.29 EJP66467.1 - 9.8e-33 113.4 0.0 7.1e-32 110.6 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP66467.1 - 8.1e-11 41.6 0.6 3.4e-10 39.5 0.6 2.2 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EJP66467.1 - 3.5e-05 23.7 0.1 0.00052 20.0 0.1 2.7 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 EJP66467.1 - 0.00017 21.9 0.1 0.03 14.6 0.0 3.4 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.12 EJP66467.1 - 0.00045 20.0 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EJP66467.1 - 0.0023 18.4 14.2 0.0031 17.9 0.0 4.4 4 2 1 5 5 4 2 AAA ATPase domain AAA_5 PF07728.14 EJP66467.1 - 0.0033 17.4 0.0 0.026 14.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EJP66467.1 - 0.0036 16.5 0.0 0.0073 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EJP66467.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 EJP66467.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein RNA_helicase PF00910.22 EJP66467.1 - 0.012 16.0 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 EJP66467.1 - 0.023 14.5 0.0 0.074 12.8 0.0 1.9 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EJP66467.1 - 0.025 14.3 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EJP66467.1 - 0.026 15.1 0.0 0.026 15.1 0.0 3.0 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EJP66467.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EJP66467.1 - 0.056 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF3435 PF11917.8 EJP66467.1 - 0.065 12.2 10.9 0.11 11.4 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) AAA_19 PF13245.6 EJP66467.1 - 0.081 13.3 0.0 0.33 11.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EJP66467.1 - 0.091 12.9 0.0 0.091 12.9 0.0 4.7 5 1 0 5 5 4 0 AAA domain LUD_dom PF02589.15 EJP66467.1 - 0.62 9.7 3.2 3.1 7.5 0.2 2.3 1 1 1 2 2 2 0 LUD domain AAA_11 PF13086.6 EJP66467.1 - 0.9 9.3 27.6 11 5.8 23.2 2.9 1 1 1 2 2 2 0 AAA domain LicD PF04991.13 EJP66467.1 - 3.8 7.6 6.5 0.58 10.3 0.9 2.2 2 0 0 2 2 2 0 LicD family OPT PF03169.15 EJP66468.1 - 2e-138 462.8 49.7 2.3e-138 462.5 49.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NUDIX PF00293.28 EJP66470.1 - 3.7e-14 52.9 0.9 4.5e-13 49.4 0.9 2.0 1 1 0 1 1 1 1 NUDIX domain DUF3446 PF11928.8 EJP66470.1 - 0.039 14.3 6.6 0.063 13.6 6.6 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain Herpes_pp85 PF04637.12 EJP66470.1 - 0.16 10.3 3.8 0.22 9.9 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) ABA_GPCR PF12430.8 EJP66471.1 - 8e-53 178.9 0.7 1.1e-52 178.4 0.7 1.2 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EJP66471.1 - 1.9e-24 85.5 0.2 6.8e-23 80.5 0.0 2.6 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Usp PF00582.26 EJP66472.1 - 3.6e-15 56.7 1.0 3.4e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 Universal stress protein family Paf67 PF10255.9 EJP66473.1 - 1e-155 518.8 0.3 1.2e-155 518.5 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EJP66473.1 - 0.058 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 EJP66474.1 - 2.2e-58 197.0 0.0 6.3e-58 195.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EJP66474.1 - 9e-17 60.9 0.0 2e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EJP66474.1 - 1.8e-09 37.8 0.0 5e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EJP66474.1 - 1.3e-07 31.6 0.0 4.7e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EJP66474.1 - 0.031 14.4 0.0 0.092 12.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase EFG_IV PF03764.18 EJP66474.1 - 0.037 13.8 0.0 1.3 8.8 0.0 3.0 3 0 0 3 3 3 0 Elongation factor G, domain IV DOT1 PF08123.13 EJP66476.1 - 6.8e-72 241.3 0.0 1.4e-71 240.3 0.0 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EJP66476.1 - 0.021 15.5 0.1 0.047 14.4 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EJP66476.1 - 0.028 14.0 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 EJP66476.1 - 0.19 11.0 0.1 0.34 10.2 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ATG16 PF08614.11 EJP66477.1 - 1.4e-51 175.6 15.2 1.6e-51 175.4 15.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 EJP66477.1 - 0.014 15.1 11.3 0.027 14.2 11.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Golgin_A5 PF09787.9 EJP66477.1 - 0.016 14.7 11.7 0.026 14.0 11.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Uds1 PF15456.6 EJP66477.1 - 0.05 13.8 11.4 0.13 12.4 10.7 2.1 2 1 0 2 2 2 0 Up-regulated During Septation SurA_N PF09312.11 EJP66477.1 - 0.06 13.4 3.7 0.33 11.0 3.1 2.3 2 1 0 2 2 2 0 SurA N-terminal domain APG6_N PF17675.1 EJP66477.1 - 0.15 12.5 18.6 0.59 10.7 18.0 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 EJP66477.1 - 1.7 7.7 9.0 2.2 7.3 9.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 EJP66477.1 - 9.7 6.2 13.3 87 3.1 13.3 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MFS_1 PF07690.16 EJP66478.1 - 1.3e-14 53.9 35.4 1.3e-14 53.9 35.4 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2417 PF10329.9 EJP66480.1 - 9.8e-84 280.5 3.0 1.2e-83 280.1 3.0 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF5134 PF17197.4 EJP66480.1 - 0.027 14.4 6.4 0.15 12.0 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) DUF2768 PF10966.8 EJP66480.1 - 0.15 12.6 0.4 0.15 12.6 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) DUF2070 PF09843.9 EJP66480.1 - 1.9 6.7 10.8 2.6 6.2 10.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RhoGAP PF00620.27 EJP66481.1 - 4.5e-34 117.5 0.0 1.5e-33 115.8 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EJP66481.1 - 1.3e-29 102.2 37.1 3.8e-12 46.2 5.7 4.9 5 0 0 5 5 5 4 LIM domain TFIIA PF03153.13 EJP66481.1 - 1.5 8.7 25.5 0.31 11.0 18.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 EJP66481.1 - 2.3 8.1 16.7 0.23 11.4 10.6 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) 3Beta_HSD PF01073.19 EJP66482.1 - 4.1e-66 222.8 0.0 5.2e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EJP66482.1 - 9.2e-33 113.7 0.2 1.9e-32 112.7 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP66482.1 - 5.4e-18 65.5 0.0 1.3e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EJP66482.1 - 3.4e-17 62.5 0.2 7.1e-17 61.4 0.2 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EJP66482.1 - 7.9e-15 54.7 0.0 7.1e-12 45.0 0.1 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EJP66482.1 - 2.2e-11 44.0 0.1 3.2e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EJP66482.1 - 6.4e-08 32.1 0.0 1.5e-06 27.6 0.2 2.9 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein KR PF08659.10 EJP66482.1 - 9.4e-05 22.4 1.0 0.00098 19.1 1.0 2.2 1 1 0 1 1 1 1 KR domain DapB_N PF01113.20 EJP66482.1 - 0.021 15.0 0.0 0.049 13.8 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pkinase PF00069.25 EJP66483.1 - 1.6e-10 40.8 0.0 3.7e-07 29.8 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Phytase-like PF13449.6 EJP66484.1 - 0.049 13.6 0.0 0.45 10.4 0.0 2.2 1 1 0 2 2 2 0 Esterase-like activity of phytase SOG2 PF10428.9 EJP66485.1 - 9 5.4 14.5 12 4.9 14.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein HMG_box PF00505.19 EJP66486.1 - 3.4e-09 37.0 0.8 1.1e-07 32.2 0.1 3.8 3 2 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EJP66486.1 - 2.3e-08 34.5 1.3 9.8e-06 26.1 0.6 3.4 3 2 0 3 3 3 2 HMG-box domain Protamine_like PF06382.11 EJP66486.1 - 0.013 15.6 0.2 0.013 15.6 0.2 2.8 1 1 0 2 2 2 0 Protamine and protamine like DIOX_N PF14226.6 EJP66486.1 - 0.043 14.6 2.6 1.3 9.8 0.1 2.8 2 1 1 3 3 3 0 non-haem dioxygenase in morphine synthesis N-terminal RNA_pol_Rpc4 PF05132.14 EJP66486.1 - 5.4 7.4 15.2 0.61 10.5 10.0 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Proteasome PF00227.26 EJP66487.1 - 1.2e-30 106.4 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Adeno_shaft PF00608.17 EJP66487.1 - 0.15 11.9 0.3 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) SIS PF01380.22 EJP66488.1 - 1.3e-59 199.7 0.1 3.8e-32 110.9 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EJP66488.1 - 1.4e-17 64.1 0.0 2.9e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EJP66488.1 - 4.6e-11 42.7 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EJP66488.1 - 0.00083 18.3 0.0 0.0017 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA PF00004.29 EJP66489.1 - 6.1e-42 143.2 0.0 1e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP66489.1 - 7.3e-11 41.7 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EJP66489.1 - 1.8e-10 40.6 0.1 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EJP66489.1 - 7e-07 29.8 0.0 0.00033 21.1 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EJP66489.1 - 6.9e-06 26.3 0.0 3.4e-05 24.0 0.0 2.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EJP66489.1 - 7.8e-06 25.9 0.1 0.00017 21.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EJP66489.1 - 1.5e-05 24.8 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EJP66489.1 - 0.00079 18.7 0.0 0.002 17.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EJP66489.1 - 0.00098 19.4 0.1 0.029 14.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EJP66489.1 - 0.0035 17.9 0.1 0.016 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EJP66489.1 - 0.0048 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EJP66489.1 - 0.0049 16.1 0.0 0.0092 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EJP66489.1 - 0.0059 16.4 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EJP66489.1 - 0.0061 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EJP66489.1 - 0.0099 15.9 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EJP66489.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EJP66489.1 - 0.018 14.7 0.0 0.058 13.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EJP66489.1 - 0.022 15.1 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EJP66489.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 EJP66489.1 - 0.034 13.8 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain PhoH PF02562.16 EJP66489.1 - 0.035 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 EJP66489.1 - 0.037 13.8 0.0 0.095 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EJP66489.1 - 0.039 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EJP66489.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EJP66489.1 - 0.054 12.8 1.3 0.13 11.6 0.0 2.3 4 0 0 4 4 3 0 KaiC AAA_11 PF13086.6 EJP66489.1 - 0.073 12.9 0.4 0.77 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain eIF-1a PF01176.19 EJP66489.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 AAA_30 PF13604.6 EJP66489.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EJP66489.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EJP66489.1 - 0.16 11.8 0.1 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Mago-bind PF09282.10 EJP66490.1 - 6e-14 51.6 1.7 6e-14 51.6 1.7 2.2 2 0 0 2 2 2 1 Mago binding UCR_UQCRX_QCR9 PF05365.12 EJP66491.1 - 4.3e-24 84.2 3.7 6.3e-24 83.7 3.7 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.20 EJP66492.1 - 8.9e-18 64.2 16.0 2.5e-17 62.8 16.0 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EJP66492.1 - 8.1e-07 28.7 0.0 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CRC_subunit PF08624.10 EJP66493.1 - 7.6e-53 178.6 0.0 1.3e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Dpy-30 PF05186.13 EJP66493.1 - 0.098 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Dpy-30 motif RR_TM4-6 PF06459.12 EJP66493.1 - 0.41 10.4 3.4 0.69 9.7 3.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 EJP66493.1 - 0.53 9.6 5.4 0.77 9.1 5.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EJP66493.1 - 5 5.3 4.4 6.9 4.8 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SecE PF00584.20 EJP66494.1 - 1.3e-14 53.8 0.0 1.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Cyclin PF08613.11 EJP66495.1 - 1e-08 35.7 0.0 2.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin Complex1_LYR_2 PF13233.6 EJP66495.1 - 0.017 15.8 0.0 0.037 14.8 0.0 1.6 1 1 0 1 1 1 0 Complex1_LYR-like PriC PF07445.12 EJP66495.1 - 0.19 11.6 4.9 0.32 10.9 4.9 1.2 1 0 0 1 1 1 0 Primosomal replication protein priC Nefa_Nip30_N PF10187.9 EJP66496.1 - 1.4e-27 96.1 9.8 1.4e-27 96.1 9.8 2.8 3 0 0 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Caldesmon PF02029.15 EJP66496.1 - 0.18 10.5 32.3 0.24 10.1 32.3 1.0 1 0 0 1 1 1 0 Caldesmon Tim54 PF11711.8 EJP66497.1 - 6.4e-140 466.2 0.4 7.5e-140 466.0 0.4 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 EJP66498.1 - 6.6e-58 196.1 0.0 7.6e-57 192.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66498.1 - 6.9e-27 94.4 0.2 1.3e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EJP66498.1 - 6.8e-05 22.9 0.3 0.019 14.9 0.4 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EJP66498.1 - 7.4e-05 21.9 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EJP66498.1 - 0.00073 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJP66498.1 - 0.0013 18.2 0.8 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EJP66498.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EJP66498.1 - 0.92 9.1 2.9 0.9 9.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family SF3A2 PF16835.5 EJP66499.1 - 1.5e-35 121.4 0.2 2.2e-35 120.9 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EJP66499.1 - 4e-06 27.0 0.9 7e-06 26.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EJP66499.1 - 1.1e-05 25.4 0.2 1.6e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 EJP66499.1 - 0.066 12.8 1.5 0.11 12.0 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GN3L_Grn1 PF08701.11 EJP66501.1 - 1.5e-24 85.8 13.4 4.1e-24 84.5 13.4 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EJP66501.1 - 1.3e-16 60.7 0.1 1.6e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP66501.1 - 1.7e-07 31.3 0.0 6.2e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EJP66501.1 - 2.2e-05 24.6 2.0 0.027 14.5 0.1 3.5 3 1 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EJP66501.1 - 7.4e-05 22.4 0.0 0.28 10.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EJP66501.1 - 0.0024 17.4 0.1 0.035 13.6 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EJP66501.1 - 0.069 12.1 0.8 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 EJP66501.1 - 0.081 12.2 0.1 0.42 9.9 0.0 2.0 2 0 0 2 2 2 0 AIG1 family AAA_16 PF13191.6 EJP66501.1 - 0.19 12.1 0.0 0.19 12.1 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain BUD22 PF09073.10 EJP66501.1 - 0.46 9.8 22.8 0.87 8.9 22.8 1.4 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 EJP66501.1 - 0.79 8.2 5.8 1 7.8 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CNDH2_C PF16858.5 EJP66501.1 - 0.8 9.5 13.6 1.5 8.7 13.6 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RNB PF00773.19 EJP66502.1 - 5.2e-99 331.7 0.1 7.6e-99 331.1 0.1 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EJP66502.1 - 8.1e-32 109.1 0.1 2.6e-31 107.4 0.1 1.9 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 EJP66502.1 - 3.4e-29 101.5 0.1 1.1e-28 99.8 0.1 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 EJP66502.1 - 1.2e-19 70.1 0.0 3.5e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EJP66502.1 - 4e-11 43.3 0.1 1.5e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 EJP66502.1 - 2.5e-07 30.8 0.5 0.047 13.9 0.0 3.1 4 0 0 4 4 4 2 Cold shock domain TcfC PF16967.5 EJP66502.1 - 0.12 11.9 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 E-set like domain Dis3l2_C_term PF17877.1 EJP66502.1 - 0.13 12.6 0.0 0.51 10.7 0.0 2.0 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal CRC_subunit PF08624.10 EJP66503.1 - 1.3e-51 174.5 0.1 1.8e-51 174.1 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Shisa PF13908.6 EJP66504.1 - 0.045 14.0 0.9 0.093 13.0 0.1 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DFRP_C PF16543.5 EJP66504.1 - 0.092 13.2 0.1 0.16 12.5 0.1 1.3 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 CYYR1 PF10873.8 EJP66504.1 - 8 6.9 6.1 5.5 7.4 0.0 2.8 3 0 0 3 3 3 0 Cysteine and tyrosine-rich protein 1 CBFD_NFYB_HMF PF00808.23 EJP66505.1 - 5.3e-10 39.4 0.3 1.1e-09 38.4 0.3 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EJP66505.1 - 7.3e-08 32.8 0.3 7.3e-08 32.8 0.3 2.7 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EJP66505.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAFII28 PF04719.14 EJP66505.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TFIIA PF03153.13 EJP66505.1 - 1.1 9.2 25.6 1.5 8.7 25.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_capsid PF06112.11 EJP66506.1 - 8 6.5 20.2 15 5.6 20.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Zn_clus PF00172.18 EJP66508.1 - 3.4e-08 33.5 11.9 5.7e-08 32.7 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4805 PF16063.5 EJP66508.1 - 0.21 10.9 4.6 0.46 9.8 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) HLH PF00010.26 EJP66509.1 - 1.6e-12 47.1 0.4 4.5e-12 45.7 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4776 PF16003.5 EJP66509.1 - 0.082 11.9 1.0 0.11 11.4 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) PRKG1_interact PF15898.5 EJP66509.1 - 0.099 13.6 0.0 0.099 13.6 0.0 2.6 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain VSP PF03302.13 EJP66510.1 - 3.1e-05 23.0 0.6 4.3e-05 22.5 0.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF347 PF03988.12 EJP66510.1 - 0.01 16.0 2.0 0.023 14.9 2.0 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Asp PF00026.23 EJP66510.1 - 0.078 12.4 0.0 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic aspartyl protease TPR_1 PF00515.28 EJP66511.1 - 9.7e-23 79.0 2.5 1.5e-06 27.7 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP66511.1 - 1e-20 72.1 5.4 4.5e-06 26.4 0.1 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EJP66511.1 - 5e-18 64.5 4.9 5.4e-08 32.4 0.0 4.9 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 EJP66511.1 - 1.1e-17 64.3 7.0 2.5e-07 31.2 2.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EJP66511.1 - 1.2e-15 57.7 5.6 0.00017 22.0 0.4 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EJP66511.1 - 3.2e-15 55.5 11.3 5.7e-05 23.6 0.5 6.1 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJP66511.1 - 4.2e-13 48.7 3.5 0.033 14.6 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EJP66511.1 - 6.3e-12 44.6 2.3 0.005 16.8 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP66511.1 - 3.8e-11 42.3 5.6 2e-05 24.4 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EJP66511.1 - 2.9e-08 33.8 5.0 1 10.1 0.1 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJP66511.1 - 5.6e-08 33.0 7.7 0.025 14.9 1.4 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EJP66511.1 - 5.6e-08 32.8 3.1 0.0016 18.5 0.5 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EJP66511.1 - 1.1e-05 25.7 14.2 0.0036 17.6 0.1 4.9 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 EJP66511.1 - 0.00021 20.6 6.3 0.13 11.4 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP66511.1 - 0.0088 16.2 4.2 1.5 9.1 0.2 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 NatB_MDM20 PF09797.9 EJP66511.1 - 0.02 13.8 0.0 0.044 12.7 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF484 PF04340.12 EJP66511.1 - 0.043 13.5 0.1 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF484 DUF1641 PF07849.11 EJP66511.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF4919 PF16266.5 EJP66511.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_10 PF13374.6 EJP66511.1 - 6.5 6.8 7.7 3 7.8 0.4 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Brix PF04427.18 EJP66512.1 - 3e-45 154.7 0.3 4.9e-45 154.0 0.3 1.4 1 0 0 1 1 1 1 Brix domain Fungal_trans_2 PF11951.8 EJP66513.1 - 0.00043 19.2 0.1 0.00064 18.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1902 PF08972.11 EJP66513.1 - 0.16 12.0 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Cys_Met_Meta_PP PF01053.20 EJP66514.1 - 3.8e-141 470.0 0.1 4.3e-141 469.9 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EJP66514.1 - 1.4e-09 37.6 0.1 2.1e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EJP66514.1 - 7.7e-07 28.4 1.0 9.5e-07 28.1 0.3 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EJP66514.1 - 1.4e-06 27.9 0.6 2.4e-06 27.1 0.6 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EJP66514.1 - 0.0055 15.3 0.0 0.0081 14.7 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase 2-Hacid_dh PF00389.30 EJP66514.1 - 0.0096 15.6 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Beta_elim_lyase PF01212.21 EJP66514.1 - 0.085 12.1 0.5 0.15 11.3 0.5 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Glutaredoxin PF00462.24 EJP66515.1 - 1.4e-13 50.9 0.0 3.1e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EJP66515.1 - 0.00028 21.2 0.0 0.00065 20.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Vps16_C PF04840.12 EJP66516.1 - 1.6e-83 280.4 0.0 2.5e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 EJP66516.1 - 7.9e-80 268.6 0.0 1.2e-79 268.0 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 EJP66516.1 - 0.00062 20.0 0.0 0.12 12.6 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJP66516.1 - 0.22 12.5 0.8 10 7.2 0.1 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat VCBS PF13517.6 EJP66517.1 - 0.15 12.7 2.2 0.23 12.1 0.3 2.4 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ATP_bind_3 PF01171.20 EJP66518.1 - 1.3e-41 142.4 0.3 3.7e-29 101.8 0.0 3.0 3 0 0 3 3 3 2 PP-loop family NUDIX PF00293.28 EJP66520.1 - 6.9e-10 39.1 1.8 4.6e-09 36.4 1.8 1.9 1 1 0 1 1 1 1 NUDIX domain Ribosomal_60s PF00428.19 EJP66520.1 - 0.038 14.6 3.5 0.084 13.5 3.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Vps39_1 PF10366.9 EJP66521.1 - 8.6e-32 109.6 0.1 3.2e-30 104.6 0.0 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EJP66521.1 - 6.2e-26 91.0 0.0 1.5e-25 89.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EJP66521.1 - 9.9e-11 41.8 0.0 5e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 EJP66521.1 - 0.0015 18.4 3.7 0.0064 16.4 0.2 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS ANAPC3 PF12895.7 EJP66521.1 - 0.0015 18.7 2.5 0.68 10.2 0.2 3.7 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EJP66521.1 - 0.0028 18.1 5.4 0.46 11.0 0.3 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP66521.1 - 0.0069 16.2 6.6 3.5 7.6 0.8 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EJP66521.1 - 0.01 15.9 3.0 43 4.6 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EJP66521.1 - 0.052 14.2 0.3 0.91 10.2 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Gon7 PF08738.10 EJP66522.1 - 7.4e-11 42.1 4.7 1e-10 41.6 1.3 1.9 1 1 1 2 2 2 1 Gon7 family Sporozoite_P67 PF05642.11 EJP66522.1 - 0.056 11.5 3.3 0.059 11.5 3.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Roughex PF06020.11 EJP66522.1 - 0.06 12.4 4.6 0.067 12.3 4.6 1.0 1 0 0 1 1 1 0 Drosophila roughex protein HbrB PF08539.11 EJP66523.1 - 2.1e-48 164.5 1.6 2.2e-48 164.4 0.1 1.9 2 0 0 2 2 2 1 HbrB-like LIM_bind PF01803.16 EJP66524.1 - 1.8e-72 243.8 0.0 1.8e-72 243.8 0.0 5.5 2 1 1 3 3 3 1 LIM-domain binding protein 6PF2K PF01591.18 EJP66526.1 - 1.1e-77 260.3 0.1 1.3e-77 260.0 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EJP66526.1 - 1.7e-34 119.2 0.0 3.9e-34 118.1 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EJP66526.1 - 6.7e-06 26.3 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EJP66526.1 - 1.9e-05 24.3 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF816 PF05674.12 EJP66526.1 - 0.0052 16.7 0.5 0.0092 15.9 0.5 1.3 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF816) Zeta_toxin PF06414.12 EJP66526.1 - 0.14 11.4 0.0 2.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Asp PF00026.23 EJP66527.1 - 7.1e-36 124.2 0.1 1e-35 123.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EJP66527.1 - 4.1e-06 27.4 0.1 0.31 11.7 0.0 3.6 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EJP66527.1 - 0.016 15.0 0.0 0.18 11.6 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EJP66527.1 - 0.031 14.8 0.0 17 6.1 0.0 3.1 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 EJP66527.1 - 0.085 13.1 6.0 1.7 8.9 3.2 3.4 3 1 0 3 3 3 0 Xylanase inhibitor N-terminal DUF829 PF05705.14 EJP66528.1 - 2e-37 129.4 0.0 3e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) NMN_transporter PF04973.12 EJP66528.1 - 0.067 13.2 0.3 0.13 12.2 0.1 1.5 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter FAM76 PF16046.5 EJP66529.1 - 0.0069 15.8 0.4 0.01 15.2 0.4 1.2 1 0 0 1 1 1 1 FAM76 protein KH_1 PF00013.29 EJP66530.1 - 3.8e-46 154.8 13.0 2.7e-16 59.2 1.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EJP66530.1 - 2.4e-12 46.5 7.5 0.0012 18.6 0.1 3.5 4 0 0 4 4 4 3 KH domain KH_4 PF13083.6 EJP66530.1 - 9.4e-08 31.8 8.3 0.087 12.7 0.1 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EJP66530.1 - 2.1e-05 24.4 0.0 0.58 10.2 0.0 3.3 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 EJP66530.1 - 0.00016 21.7 3.2 0.99 9.5 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain SLS PF14611.6 EJP66530.1 - 0.16 11.8 0.0 35 4.1 0.0 2.9 2 1 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator DUF3337 PF11816.8 EJP66531.1 - 4.9e-55 186.0 0.0 1.1e-54 184.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EJP66531.1 - 4.6e-12 46.2 13.5 0.0098 16.7 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EJP66531.1 - 0.0014 17.4 0.2 0.028 13.1 0.0 2.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Mito_carr PF00153.27 EJP66532.1 - 1.5e-43 146.6 9.0 7.4e-18 64.3 0.3 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Serglycin PF04360.12 EJP66532.1 - 0.0013 18.7 1.8 0.0024 17.8 0.5 1.9 2 0 0 2 2 2 1 Serglycin Serine_protease PF18405.1 EJP66532.1 - 0.018 14.2 2.6 0.1 11.7 0.2 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Frankia_peptide PF14407.6 EJP66533.1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF4452 PF14618.6 EJP66534.1 - 3.2e-64 215.9 21.2 1.7e-63 213.5 21.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4452) Cyclin_N PF00134.23 EJP66535.1 - 1.2e-11 44.4 1.1 2.4e-11 43.5 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EJP66535.1 - 0.019 15.4 0.1 0.078 13.4 0.1 2.0 1 0 0 1 1 1 0 Cyclin C-terminal domain Turandot PF07240.11 EJP66535.1 - 0.046 13.7 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot DUF3546 PF12066.8 EJP66535.1 - 0.58 10.4 2.3 5.7 7.2 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3546) Mito_carr PF00153.27 EJP66536.1 - 3.8e-69 228.7 7.1 1.2e-25 89.3 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EJP66536.1 - 3.7e-22 76.2 5.8 4.3e-06 25.9 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 EJP66536.1 - 7.4e-19 66.3 2.3 1.2e-05 24.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EJP66536.1 - 7.6e-19 67.9 3.8 8.6e-13 48.6 0.6 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EJP66536.1 - 1e-17 62.5 4.8 5.8e-07 28.9 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EJP66536.1 - 8.4e-13 48.0 2.4 2.7e-05 23.9 0.2 3.7 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EJP66536.1 - 2.1e-05 24.8 0.1 0.00024 21.4 0.1 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Serine_protease PF18405.1 EJP66536.1 - 0.0041 16.3 1.5 0.66 9.1 0.1 3.2 3 0 0 3 3 3 1 Gammaproteobacterial serine protease EF-hand_13 PF17958.1 EJP66536.1 - 0.1 12.4 0.0 15 5.5 0.0 3.0 3 1 1 4 4 4 0 EF-hand domain DUF4097 PF13349.6 EJP66537.1 - 1e-08 34.9 0.7 3.3e-05 23.4 0.0 2.9 2 1 0 2 2 2 2 Putative adhesin Ank_5 PF13857.6 EJP66538.1 - 1.8e-11 44.0 0.2 0.00068 19.9 0.1 4.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP66538.1 - 9e-11 42.2 0.8 0.00078 20.0 0.1 5.0 3 3 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP66538.1 - 1.1e-09 38.6 1.8 0.0048 17.4 0.1 6.2 5 1 2 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP66538.1 - 2.3e-08 33.7 4.0 0.46 11.2 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EJP66538.1 - 2.2e-05 24.7 4.8 0.82 10.2 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat DEAD PF00270.29 EJP66539.1 - 9.6e-17 61.3 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EJP66539.1 - 2e-11 44.2 0.0 7.6e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EJP66539.1 - 7.5e-11 42.4 0.0 1.9e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 EJP66539.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein BRE1 PF08647.11 EJP66539.1 - 2.4 8.3 9.6 0.036 14.1 0.5 2.6 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase OPT PF03169.15 EJP66540.1 - 3.3e-130 435.6 42.9 3.8e-130 435.4 42.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 EJP66540.1 - 0.12 11.7 0.8 0.47 9.8 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3552 PF12072.8 EJP66541.1 - 8.2e-11 41.7 44.0 0.0036 16.7 9.7 5.5 3 1 2 5 5 5 5 Domain of unknown function (DUF3552) DUF390 PF04094.14 EJP66541.1 - 2.8e-10 39.2 35.8 9.7e-07 27.5 16.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF390) DUF16 PF01519.16 EJP66541.1 - 3.5 8.2 20.3 1.6 9.3 2.2 4.5 1 1 3 4 4 4 0 Protein of unknown function DUF16 UEV PF05743.13 EJP66542.1 - 8.9e-39 132.1 0.1 1.4e-38 131.4 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EJP66542.1 - 1.4e-21 76.2 0.0 4.9e-21 74.4 0.0 2.0 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 EJP66542.1 - 0.0052 16.4 0.2 0.01 15.5 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EJP66542.1 - 0.04 14.2 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 RWD domain RmuC PF02646.16 EJP66542.1 - 0.29 10.2 3.0 0.45 9.6 3.0 1.2 1 0 0 1 1 1 0 RmuC family YlqD PF11068.8 EJP66542.1 - 4.5 7.6 5.5 7.6 6.9 5.5 1.2 1 0 0 1 1 1 0 YlqD protein STE2 PF02116.15 EJP66543.1 - 6.7e-86 288.1 17.9 7.8e-86 287.9 17.9 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR TFB6 PF17110.5 EJP66546.1 - 1.8e-63 213.4 0.1 2.2e-63 213.1 0.1 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Sporozoite_P67 PF05642.11 EJP66546.1 - 0.023 12.8 0.3 0.031 12.4 0.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4564 PF15169.6 EJP66546.1 - 0.031 14.0 0.2 0.06 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Sigma70_ner PF04546.13 EJP66546.1 - 0.048 13.5 3.5 0.076 12.9 3.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 EJP66546.1 - 0.18 11.5 2.0 0.34 10.6 2.0 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 EJP66546.1 - 0.29 11.5 12.9 0.61 10.5 12.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rep_4 PF05797.11 EJP66546.1 - 0.37 9.9 2.4 0.53 9.4 2.4 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) RXT2_N PF08595.11 EJP66546.1 - 0.83 9.7 4.7 1.3 9.0 4.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pes-10 PF07149.11 EJP66546.1 - 1.6 7.7 7.6 2.2 7.2 7.6 1.1 1 0 0 1 1 1 0 Pes-10 NOA36 PF06524.12 EJP66546.1 - 2 7.6 9.7 2.9 7.2 9.7 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EJP66546.1 - 3 7.5 9.0 4.8 6.9 9.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 EJP66546.1 - 4.1 6.4 12.1 5.9 5.9 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 EJP66546.1 - 6.8 4.6 11.7 9.1 4.2 11.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi L-fibroin PF05849.11 EJP66547.1 - 0.025 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) Ribosomal_L32p PF01783.23 EJP66547.1 - 0.33 11.2 2.0 0.9 9.9 2.0 1.7 1 0 0 1 1 1 0 Ribosomal L32p protein family TRAPP PF04051.16 EJP66548.1 - 1.7e-35 121.9 0.0 1.9e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 EJP66548.1 - 0.0048 15.8 0.0 0.0052 15.7 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF4250 PF14056.6 EJP66548.1 - 0.029 14.3 0.1 0.071 13.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) WD40 PF00400.32 EJP66549.1 - 1.1e-40 136.8 4.0 4.5e-07 30.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66549.1 - 1.8e-14 53.8 0.1 0.00066 19.9 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EJP66549.1 - 0.0032 16.8 0.0 0.094 12.0 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain Nucleoporin_N PF08801.11 EJP66549.1 - 0.0091 14.8 0.4 5.5 5.6 0.0 3.2 3 1 0 3 3 3 2 Nup133 N terminal like Ge1_WD40 PF16529.5 EJP66549.1 - 0.013 14.5 0.1 2.9 6.8 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EJP66549.1 - 0.1 11.2 1.0 8.5 4.9 0.1 3.3 1 1 4 5 5 5 0 Nucleoporin Nup120/160 HemY_N PF07219.13 EJP66550.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.2 1 1 1 2 2 2 0 HemY protein N-terminus zf-CCHC PF00098.23 EJP66551.1 - 2.9e-45 150.4 60.8 5.8e-08 32.5 2.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EJP66551.1 - 5.5e-10 38.8 39.0 0.16 11.7 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 EJP66551.1 - 4.6e-05 23.3 42.0 0.057 13.4 0.1 6.9 3 2 3 6 6 6 3 Zinc knuckle zf-CCHC_5 PF14787.6 EJP66551.1 - 6.8e-05 22.5 44.6 0.0069 16.1 1.0 7.1 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 EJP66551.1 - 0.059 13.2 2.0 0.059 13.2 2.0 7.1 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.6 EJP66551.1 - 0.33 10.8 0.1 0.33 10.8 0.1 6.9 6 1 1 7 7 7 0 Zinc knuckle DUF2353 PF09789.9 EJP66552.1 - 0.00041 19.8 2.0 0.00069 19.1 2.0 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) SHE3 PF17078.5 EJP66552.1 - 0.0041 16.9 2.2 0.0076 16.0 1.9 1.6 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF4763 PF15960.5 EJP66552.1 - 0.005 16.2 0.9 0.023 14.0 0.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4763) End3 PF12761.7 EJP66552.1 - 0.0057 16.9 2.7 0.01 16.1 2.7 1.4 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 FlgN PF05130.12 EJP66552.1 - 0.022 15.3 3.1 0.022 15.3 3.1 2.2 1 1 1 2 2 2 0 FlgN protein SPATA24 PF15175.6 EJP66552.1 - 0.022 14.7 0.2 0.1 12.5 0.1 2.1 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 PRKG1_interact PF15898.5 EJP66552.1 - 0.12 13.3 5.2 0.36 11.8 0.1 2.6 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain GLTP PF08718.11 EJP66552.1 - 0.13 12.6 0.9 0.29 11.4 0.9 1.7 1 1 0 1 1 1 0 Glycolipid transfer protein (GLTP) DUF932 PF06067.11 EJP66552.1 - 0.16 11.7 5.1 0.13 12.0 3.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF932) TEX13 PF15186.6 EJP66552.1 - 0.24 11.1 5.6 0.61 9.8 2.2 2.6 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family Spc7 PF08317.11 EJP66552.1 - 0.31 9.9 4.8 0.32 9.8 3.0 1.8 1 1 0 2 2 2 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 EJP66552.1 - 0.36 10.9 8.4 4.4 7.4 0.4 3.5 3 0 0 3 3 3 0 TolA binding protein trimerisation Fib_alpha PF08702.10 EJP66552.1 - 0.37 11.0 1.5 2.6 8.2 0.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 EJP66552.1 - 0.46 9.3 0.7 0.66 8.8 0.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_Mu_Gam PF07352.12 EJP66552.1 - 0.66 9.9 3.1 0.92 9.4 0.4 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein KASH_CCD PF14662.6 EJP66552.1 - 0.93 9.3 6.1 7.5 6.3 3.1 2.8 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Mto2_bdg PF12808.7 EJP66552.1 - 6.3 7.2 10.0 3.7 7.9 1.0 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region zf-UBR PF02207.20 EJP66553.1 - 8.1e-14 51.5 6.0 8.1e-14 51.5 6.0 3.5 4 1 1 5 5 5 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 EJP66554.1 - 2.2e-99 331.1 0.0 4.3e-99 330.1 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJP66554.1 - 3.7e-39 133.4 0.2 7.3e-39 132.5 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EJP66554.1 - 9.2e-33 113.7 34.4 9.2e-33 113.7 34.4 2.5 4 0 0 4 4 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EJP66554.1 - 1.7e-25 89.2 1.0 5.9e-25 87.5 1.0 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EJP66554.1 - 2e-14 54.0 1.7 5.2e-14 52.7 0.1 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EJP66554.1 - 7.5e-07 28.7 0.0 1.2e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EJP66554.1 - 2.2e-05 24.5 0.0 4.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EJP66554.1 - 0.021 14.7 0.0 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJP66554.1 - 0.024 14.3 0.2 0.1 12.3 0.2 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain 7tm_3 PF00003.22 EJP66554.1 - 0.16 11.7 0.3 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR zf-TFIIB PF13453.6 EJP66554.1 - 0.22 10.9 2.0 0.69 9.3 2.0 1.9 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.10 EJP66554.1 - 0.35 11.0 1.3 1 9.5 1.3 1.8 1 0 0 1 1 1 0 Zinc ribbon domain Sugar_tr PF00083.24 EJP66556.1 - 1.3e-69 235.2 0.7 1.5e-69 235.0 0.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP66556.1 - 1e-17 64.1 9.0 1.3e-17 63.8 9.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_16 PF13432.6 EJP66556.1 - 0.074 13.7 0.4 0.16 12.6 0.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RVT_2 PF07727.14 EJP66557.1 - 0.016 14.9 0.2 0.024 14.3 0.2 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Sugar_tr PF00083.24 EJP66558.1 - 1.2e-39 136.4 9.9 1.4e-39 136.2 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP66558.1 - 5.1e-08 32.2 4.0 6.4e-08 31.9 4.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Endotoxin_N PF03945.14 EJP66559.1 - 8.8e-22 77.9 0.0 2.3e-19 70.0 0.0 2.3 2 0 0 2 2 2 2 delta endotoxin, N-terminal domain Glyco_hydro_31 PF01055.26 EJP66560.1 - 1.2e-147 492.7 1.8 1.5e-147 492.4 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EJP66560.1 - 3.8e-38 130.2 0.0 6.2e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EJP66560.1 - 1.6e-14 54.0 2.8 2.7e-14 53.2 0.5 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EJP66560.1 - 0.13 12.5 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) zf-C2H2 PF00096.26 EJP66561.1 - 0.0044 17.4 17.8 0.11 13.0 1.0 4.2 3 1 0 3 3 3 2 Zinc finger, C2H2 type Peptidase_C14 PF00656.22 EJP66561.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Caspase domain AbiEi_4 PF13338.6 EJP66561.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin zf-C2H2_4 PF13894.6 EJP66561.1 - 0.33 11.9 20.9 0.29 12.1 1.2 4.9 4 1 0 4 4 4 0 C2H2-type zinc finger Sina PF03145.16 EJP66561.1 - 0.34 10.8 4.0 0.63 10.0 4.0 1.4 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_jaz PF12171.8 EJP66561.1 - 0.42 11.0 3.1 10 6.5 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Patatin PF01734.22 EJP66562.1 - 2.8e-14 53.8 0.0 8.1e-14 52.3 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Fungal_trans_2 PF11951.8 EJP66563.1 - 2.2e-08 33.3 0.6 1.4e-07 30.7 0.6 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66563.1 - 1.3e-06 28.4 11.8 2.4e-06 27.5 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 EJP66563.1 - 0.41 10.2 10.3 0.42 10.2 2.8 2.6 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 EJP66563.1 - 2.4 7.2 7.2 4.8 6.2 7.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein GFO_IDH_MocA PF01408.22 EJP66565.1 - 2.7e-15 57.2 0.2 5.2e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sec23_helical PF04815.15 EJP66565.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain GFO_IDH_MocA_C PF02894.17 EJP66565.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Peptidase_S8 PF00082.22 EJP66566.1 - 1.2e-29 103.5 5.6 2.6e-29 102.4 5.6 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJP66566.1 - 5.7e-08 33.3 0.1 3.6e-07 30.7 0.1 2.3 2 1 0 2 2 2 1 Peptidase inhibitor I9 4HBT PF03061.22 EJP66567.1 - 6.4e-09 36.1 0.1 9.6e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EJP66567.1 - 6.7e-07 29.8 0.0 8.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EJP66567.1 - 7.4e-05 22.2 1.0 0.00014 21.2 1.0 1.4 2 0 0 2 2 2 1 Acyl-ACP thioesterase PseudoU_synth_2 PF00849.22 EJP66568.1 - 1e-30 106.9 0.0 1.7e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.12 EJP66568.1 - 0.031 14.4 0.1 0.071 13.3 0.1 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DMPK_coil PF08826.10 EJP66570.1 - 0.06 13.5 9.7 0.85 9.8 9.5 2.3 1 1 0 1 1 1 0 DMPK coiled coil domain like bZIP_1 PF00170.21 EJP66570.1 - 0.095 12.8 15.2 0.64 10.2 15.2 2.2 1 1 0 1 1 1 0 bZIP transcription factor Adaptin_binding PF10199.9 EJP66570.1 - 8.8 7.0 13.8 0.58 10.8 3.4 2.4 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Glyco_hydro_3_C PF01915.22 EJP66571.1 - 4.1e-61 206.5 0.0 1.6e-60 204.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EJP66571.1 - 2.3e-45 155.4 0.0 3.7e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EJP66571.1 - 8.1e-23 80.3 0.0 1.7e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EJP66571.1 - 3.7e-21 75.5 0.0 7e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain FTA4 PF13093.6 EJP66573.1 - 3.4e-56 190.3 0.6 4.3e-56 190.0 0.6 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RPE65 PF03055.15 EJP66574.1 - 4.7e-114 382.1 0.0 5.4e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GH43_C2 PF17851.1 EJP66575.1 - 0.14 11.8 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain Peptidase_M20 PF01546.28 EJP66576.1 - 3.1e-07 30.3 0.0 4.6e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJP66576.1 - 1.6e-06 28.0 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain SPDY PF03771.16 EJP66576.1 - 0.087 12.8 0.2 0.27 11.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF317) Zn_clus PF00172.18 EJP66577.1 - 1.3e-07 31.6 7.6 2.1e-07 30.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP66577.1 - 1.8e-07 30.3 0.3 3e-07 29.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Clusterin PF01093.17 EJP66577.1 - 0.1 11.7 1.1 0.2 10.6 0.5 1.7 2 0 0 2 2 2 0 Clusterin HipN PF18253.1 EJP66577.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain DCP2 PF05026.13 EJP66579.1 - 1.7e-30 105.1 0.7 3.2e-30 104.3 0.7 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EJP66579.1 - 1.3e-16 60.9 0.0 2.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Caroten_synth PF04240.12 EJP66581.1 - 0.047 13.6 0.8 0.56 10.0 0.1 2.2 2 0 0 2 2 2 0 Carotenoid biosynthesis protein WD40 PF00400.32 EJP66582.1 - 1.2e-14 54.4 3.3 4e-07 30.6 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66582.1 - 3.2e-05 24.1 0.0 0.15 12.3 0.0 4.2 1 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 EJP66583.1 - 5.3e-56 186.5 1.7 4.9e-19 68.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CTU2 PF10288.9 EJP66584.1 - 9.8e-11 41.9 0.0 1.5e-08 34.9 0.0 2.5 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Abhydrolase_6 PF12697.7 EJP66584.1 - 0.04 14.5 5.8 0.26 11.9 1.6 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF1289 PF06945.13 EJP66584.1 - 0.24 11.2 2.1 7.9 6.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DZR PF12773.7 EJP66584.1 - 0.49 10.5 3.6 0.93 9.6 0.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon PH PF00169.29 EJP66585.1 - 4e-26 91.6 3.6 5.3e-14 52.6 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 EJP66585.1 - 3.7e-10 40.2 3.3 0.00013 22.3 0.6 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 EJP66585.1 - 2.1e-09 37.7 10.1 0.0008 19.8 0.9 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 EJP66585.1 - 0.0053 17.0 0.1 0.0053 17.0 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_15 PF17339.2 EJP66585.1 - 0.012 15.5 2.5 0.17 11.8 0.2 2.3 2 0 0 2 2 2 0 PH domain PH_10 PF15411.6 EJP66585.1 - 0.05 13.9 0.2 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Cellulase PF00150.18 EJP66586.1 - 1.5e-13 50.8 0.0 3.6e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Med2 PF11214.8 EJP66587.1 - 0.0035 17.5 0.1 0.0065 16.6 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 AAA_11 PF13086.6 EJP66589.1 - 8.2e-17 61.8 0.0 2.5e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP66589.1 - 1.7e-06 27.9 0.0 3.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP66589.1 - 7.1e-06 26.4 0.0 2.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EJP66589.1 - 0.00056 19.8 0.2 0.0041 17.0 0.0 2.3 2 0 0 2 2 2 1 Helicase ResIII PF04851.15 EJP66589.1 - 0.0023 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EJP66589.1 - 0.0035 16.6 0.1 0.017 14.4 0.0 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EJP66589.1 - 0.0036 16.8 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 EJP66589.1 - 0.005 17.1 0.4 0.07 13.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EJP66589.1 - 0.025 14.6 0.1 0.95 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 EJP66589.1 - 0.066 13.0 0.1 1.2 8.9 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.29 EJP66589.1 - 0.18 12.2 0.6 2.1 8.8 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EJP66590.1 - 2.3e-23 83.1 0.0 3.9e-12 46.8 0.0 4.1 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EJP66590.1 - 1.3e-19 70.1 12.8 7.8e-10 38.8 0.2 4.7 4 0 0 4 4 4 3 AAA lid domain AAA_22 PF13401.6 EJP66590.1 - 4.8e-06 26.9 5.2 0.0049 17.1 0.6 4.7 4 1 0 4 4 4 2 AAA domain AAA_5 PF07728.14 EJP66590.1 - 0.00024 21.1 0.0 0.0009 19.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EJP66590.1 - 0.00062 19.5 0.0 0.012 15.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EJP66590.1 - 0.0032 17.9 1.1 0.16 12.3 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EJP66590.1 - 0.061 13.5 3.1 0.27 11.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain VirE PF05272.11 EJP66590.1 - 0.083 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Virulence-associated protein E RNA_helicase PF00910.22 EJP66590.1 - 0.19 12.2 0.0 0.64 10.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EJP66590.1 - 0.65 9.7 0.0 0.65 9.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain DUF572 PF04502.13 EJP66590.1 - 4.8 6.7 12.4 0.2 11.3 1.8 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF382 PF04037.13 EJP66591.1 - 1e-58 197.0 0.4 1e-58 197.0 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EJP66591.1 - 1.1e-18 66.7 5.9 1.2e-18 66.7 3.9 2.1 2 0 0 2 2 2 1 PSP VEFS-Box PF09733.9 EJP66592.1 - 1.9e-08 34.2 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.29 EJP66592.1 - 0.0018 18.1 5.3 0.0018 18.1 5.3 1.9 2 0 0 2 2 2 1 PHD-finger zf_C2H2_ZHX PF18387.1 EJP66592.1 - 0.0032 17.1 0.3 0.0096 15.5 0.3 1.8 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain Zn_ribbon_17 PF17120.5 EJP66592.1 - 0.74 9.5 4.8 2 8.1 4.8 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type LRR_4 PF12799.7 EJP66593.1 - 7.1e-05 23.1 1.8 0.38 11.2 0.3 4.2 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Arb2 PF09757.9 EJP66596.1 - 2.5e-104 348.0 0.5 3.5e-104 347.5 0.5 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EJP66596.1 - 3.3e-83 279.7 0.0 5.4e-83 279.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain HNH_2 PF13391.6 EJP66597.1 - 0.0026 17.9 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease F-box-like PF12937.7 EJP66598.1 - 4.5e-07 29.7 0.1 3.4e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EJP66598.1 - 4.7e-06 26.3 0.1 1.8e-05 24.5 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EJP66598.1 - 0.07 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 F-box EF-hand_7 PF13499.6 EJP66598.1 - 0.1 13.1 0.1 3.4 8.2 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair Brix PF04427.18 EJP66599.1 - 8.3e-39 133.7 0.0 1.1e-38 133.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Ras PF00071.22 EJP66600.1 - 2.7e-63 212.4 0.2 3.2e-63 212.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP66600.1 - 2.8e-35 121.2 0.2 3.9e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP66600.1 - 4.7e-13 49.0 0.1 6e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJP66600.1 - 8e-08 32.4 0.1 1.2e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJP66600.1 - 0.00035 20.2 0.1 0.0018 17.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EJP66600.1 - 0.00043 19.7 0.1 0.00069 19.0 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EJP66600.1 - 0.00056 19.8 0.9 0.017 15.0 0.1 2.1 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EJP66600.1 - 0.003 17.8 0.0 0.019 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EJP66600.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EJP66600.1 - 0.017 15.5 0.1 0.03 14.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EJP66600.1 - 0.018 15.1 0.1 0.046 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJP66600.1 - 0.022 15.3 0.1 0.039 14.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EJP66600.1 - 0.029 14.1 0.1 0.064 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EJP66600.1 - 0.033 13.6 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 EJP66600.1 - 0.093 12.5 0.5 0.12 12.1 0.4 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SpoIIID PF12116.8 EJP66600.1 - 0.099 12.7 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.18 EJP66600.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 EJP66600.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PAT1 PF09770.9 EJP66601.1 - 0 1284.7 0.7 0 1284.5 0.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 T3SS_needle_F PF09392.10 EJP66601.1 - 6.2 7.1 8.5 0.7 10.1 0.3 2.7 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Sin_N PF04801.13 EJP66602.1 - 6.3e-23 81.7 0.0 3.9e-22 79.1 0.0 2.1 1 1 1 2 2 2 1 Sin-like protein conserved region tRNA-synt_1g PF09334.11 EJP66603.1 - 8.1e-138 459.4 4.7 4.6e-136 453.6 4.7 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EJP66603.1 - 2.7e-09 35.9 0.4 8.2e-05 21.0 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EJP66603.1 - 0.0058 16.0 0.0 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EJP66603.1 - 0.06 13.3 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Sas10_Utp3 PF04000.15 EJP66604.1 - 7.5e-16 58.5 4.7 2.2e-15 57.0 4.7 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CDV3 PF15359.6 EJP66604.1 - 0.0021 18.5 3.8 0.0021 18.5 3.8 2.2 2 1 0 2 2 2 1 Carnitine deficiency-associated protein 3 DNA_pol_phi PF04931.13 EJP66604.1 - 0.063 11.4 6.1 0.1 10.7 6.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 EJP66604.1 - 0.29 9.7 2.6 0.41 9.1 2.6 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EMP70 PF02990.16 EJP66605.1 - 1e-204 681.0 5.1 1.5e-204 680.5 5.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4861 PF16153.5 EJP66605.1 - 0.065 12.2 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) Med4 PF10018.9 EJP66606.1 - 1.8e-40 138.7 14.9 8e-40 136.6 15.0 2.1 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HSP70 PF00012.20 EJP66606.1 - 1.9 6.5 7.2 0.17 10.0 2.9 1.4 2 0 0 2 2 2 0 Hsp70 protein DDRGK PF09756.9 EJP66606.1 - 5.9 6.4 20.7 13 5.4 20.7 1.5 1 0 0 1 1 1 0 DDRGK domain QCR10 PF09796.9 EJP66607.1 - 2.8e-25 88.1 0.1 3.5e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF3386 PF11866.8 EJP66607.1 - 0.056 12.9 0.2 0.063 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) DIE2_ALG10 PF04922.12 EJP66608.1 - 6.5e-123 410.9 11.0 8.1e-123 410.6 11.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Mucin PF01456.17 EJP66609.1 - 0.0085 16.1 6.9 0.011 15.8 6.9 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein BAF1_ABF1 PF04684.13 EJP66609.1 - 0.027 13.5 0.3 0.029 13.4 0.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.14 EJP66609.1 - 0.23 10.8 12.8 0.31 10.4 12.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lin-8 PF03353.15 EJP66609.1 - 0.48 9.9 2.6 0.59 9.6 2.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ORC6 PF05460.13 EJP66609.1 - 0.7 9.1 7.4 0.74 9.0 7.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SPX PF03105.19 EJP66609.1 - 2.4 8.0 11.5 2.8 7.8 11.5 1.1 1 0 0 1 1 1 0 SPX domain SSP160 PF06933.11 EJP66609.1 - 3 5.9 12.5 3.8 5.6 12.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Endostatin PF06482.11 EJP66609.1 - 4 6.8 6.8 5.1 6.5 6.8 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Pex14_N PF04695.13 EJP66609.1 - 5 7.8 11.0 8.4 7.0 11.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LysM PF01476.20 EJP66612.1 - 6.8e-07 29.2 0.0 0.006 16.6 0.0 2.2 2 0 0 2 2 2 2 LysM domain SOG2 PF10428.9 EJP66612.1 - 6.4 5.9 19.9 7.8 5.6 19.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 EJP66612.1 - 7.2 5.2 11.2 8.9 4.9 11.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DAO PF01266.24 EJP66613.1 - 6.6e-36 124.6 0.5 7.5e-36 124.4 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP66613.1 - 0.00056 20.1 0.3 0.0014 18.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP66613.1 - 0.0061 17.1 0.1 0.015 15.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP66613.1 - 0.0095 15.2 0.2 0.019 14.2 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EJP66613.1 - 0.029 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EJP66613.1 - 0.031 13.5 0.1 0.061 12.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EJP66613.1 - 0.047 12.5 0.2 0.07 12.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 EJP66613.1 - 0.1 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ALG3 PF05208.13 EJP66614.1 - 1.2e-142 475.7 17.6 1.4e-142 475.4 17.6 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 EJP66615.1 - 9.2e-17 60.6 0.0 1.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RTA1 PF04479.13 EJP66616.1 - 1.3e-69 234.0 2.8 1.6e-69 233.7 2.8 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3493 PF11998.8 EJP66616.1 - 0.0091 16.1 3.7 0.099 12.8 0.2 2.5 2 0 0 2 2 2 1 Low psii accumulation1 / Rep27 TssN PF17555.2 EJP66616.1 - 0.48 9.8 4.5 6.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssN DHHC PF01529.20 EJP66616.1 - 1.9 8.6 4.4 13 5.9 0.0 2.6 2 1 0 2 2 2 0 DHHC palmitoyltransferase Adaptin_N PF01602.20 EJP66617.1 - 2.1e-103 346.7 0.0 2.6e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EJP66617.1 - 2e-14 54.0 0.1 4.4e-13 49.6 0.0 3.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJP66617.1 - 1.5e-09 38.1 3.1 0.0023 18.3 0.0 5.1 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 EJP66617.1 - 6.6e-08 32.2 0.3 0.03 14.6 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Cohesin_HEAT PF12765.7 EJP66617.1 - 1.4e-05 25.3 2.7 0.053 13.8 0.0 3.2 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 EJP66617.1 - 0.0017 17.9 0.6 3.6 7.1 0.0 3.2 2 1 1 3 3 3 1 CLASP N terminal SDA1 PF05285.12 EJP66617.1 - 2.8 7.3 24.9 4.4 6.6 24.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EJP66617.1 - 4.4 5.4 29.4 7 4.7 29.4 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 EJP66617.1 - 6.4 7.2 7.4 15 6.0 7.4 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 EJP66617.1 - 6.5 5.4 7.9 9.7 4.8 7.9 1.2 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 EJP66617.1 - 9.9 5.4 22.2 17 4.6 22.2 1.3 1 0 0 1 1 1 0 BUD22 TetR_C_12 PF16914.5 EJP66621.1 - 0.0074 16.4 0.3 2.8 8.1 0.0 2.9 3 0 0 3 3 3 2 Bacterial transcriptional repressor C-terminal Nuf2 PF03800.14 EJP66623.1 - 5.9e-40 136.6 1.3 1.4e-39 135.4 0.1 2.1 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 EJP66623.1 - 4.4e-32 110.6 21.3 4.4e-32 110.6 21.3 4.3 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain Bacillus_HBL PF05791.11 EJP66623.1 - 0.57 10.0 14.3 1.5 8.6 1.6 3.4 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) VPS11_C PF12451.8 EJP66623.1 - 4.9 7.4 5.7 48 4.3 0.5 3.9 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal Thioredoxin PF00085.20 EJP66624.1 - 3.4e-26 91.2 0.2 4.3e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EJP66624.1 - 2.9e-08 33.8 0.2 4.2e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EJP66624.1 - 7e-08 32.9 0.2 2e-07 31.4 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EJP66624.1 - 6.8e-07 28.9 0.3 8.9e-07 28.5 0.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EJP66624.1 - 4.3e-06 26.5 0.0 5.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EJP66624.1 - 6.8e-06 26.3 0.1 0.0005 20.3 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like Glutaredoxin PF00462.24 EJP66624.1 - 0.00011 22.4 0.0 0.0003 20.9 0.0 1.8 1 1 1 2 2 2 1 Glutaredoxin AhpC-TSA PF00578.21 EJP66624.1 - 0.0026 17.7 0.1 0.0041 17.0 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJP66624.1 - 0.015 15.0 0.1 0.024 14.4 0.1 1.5 1 1 0 1 1 1 0 Redoxin TraF PF13728.6 EJP66624.1 - 0.018 14.9 0.1 0.024 14.5 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF4043 PF13252.6 EJP66624.1 - 0.028 13.5 0.1 0.035 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) Thioredoxin_3 PF13192.6 EJP66624.1 - 0.092 12.8 0.0 0.24 11.5 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin domain HyaE PF07449.11 EJP66624.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.5 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Colipase-like PF15083.6 EJP66625.1 - 0.088 12.9 7.0 3.3 7.9 0.6 2.6 1 1 1 2 2 2 0 Colipase-like LPP PF04728.13 EJP66625.1 - 0.14 12.5 0.4 0.51 10.8 0.0 2.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF3801 PF12687.7 EJP66625.1 - 2.7 8.0 10.8 5.2 7.1 10.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) APH PF01636.23 EJP66626.1 - 1.5e-05 25.1 0.0 8.1e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family NAD_binding_2 PF03446.15 EJP66627.1 - 5.2e-37 127.5 0.1 8.7e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EJP66627.1 - 1.3e-28 99.6 2.6 1.3e-28 99.6 0.2 2.0 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EJP66627.1 - 1.4e-05 25.6 0.1 5.1e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 EJP66627.1 - 5.3e-05 22.3 0.0 8.3e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 EJP66627.1 - 0.00063 20.5 0.1 0.0017 19.2 0.1 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 EJP66627.1 - 0.0007 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Ldh_1_N PF00056.23 EJP66627.1 - 0.00073 19.6 0.4 0.0025 17.9 0.1 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EJP66627.1 - 0.019 14.9 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3053 PF11254.8 EJP66627.1 - 0.043 13.4 0.7 3.2 7.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) Ribosom_S30AE_C PF16321.5 EJP66627.1 - 0.12 12.1 0.5 0.28 10.9 0.5 1.6 1 1 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Arrestin_C PF02752.22 EJP66628.1 - 6.4e-18 65.5 0.0 3.9e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EJP66628.1 - 6.6e-15 55.4 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EJP66628.1 - 0.028 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like WD40 PF00400.32 EJP66629.1 - 8.8e-11 42.2 10.8 0.01 16.7 0.4 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66629.1 - 3.9e-07 30.3 0.0 0.00097 19.4 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJP66629.1 - 0.0013 18.7 0.0 0.0038 17.1 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EJP66629.1 - 0.0052 15.4 0.0 0.016 13.8 0.0 1.7 1 1 1 2 2 2 2 Cytochrome D1 heme domain EF_assoc_2 PF08356.12 EJP66630.1 - 1.9e-34 117.5 0.0 4.2e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EJP66630.1 - 1.8e-29 101.1 0.1 5.6e-29 99.6 0.0 1.9 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 EJP66630.1 - 5.1e-24 84.7 0.0 1.9e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EJP66630.1 - 4.6e-14 52.7 0.0 3.4e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EJP66630.1 - 5.2e-09 36.2 0.0 0.00023 21.2 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 EJP66630.1 - 3.5e-08 32.4 5.2 0.00086 18.7 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EJP66630.1 - 7.5e-07 28.6 5.4 0.013 15.4 0.7 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EJP66630.1 - 1.4e-06 28.6 0.9 0.0026 18.2 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.23 EJP66630.1 - 6.1e-05 23.1 0.0 0.18 11.8 0.0 2.8 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.6 EJP66630.1 - 9.7e-05 22.7 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJP66630.1 - 0.00017 22.0 0.0 0.34 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EJP66630.1 - 0.00019 21.1 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EJP66630.1 - 0.001 18.6 0.0 2.5 7.6 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EJP66630.1 - 0.0013 18.6 0.0 1.1 9.1 0.1 3.3 2 1 0 3 3 3 1 RsgA GTPase Ploopntkinase3 PF18751.1 EJP66630.1 - 0.0018 18.3 0.0 0.41 10.5 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 EJP66630.1 - 0.0047 17.2 0.0 3.9 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.6 EJP66630.1 - 0.0066 15.9 5.6 0.29 10.7 2.7 2.7 2 0 0 2 2 2 1 EF hand ABC_tran PF00005.27 EJP66630.1 - 0.012 16.1 0.0 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 EJP66630.1 - 0.017 14.9 0.0 0.38 10.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EJP66630.1 - 0.017 15.2 0.0 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EJP66630.1 - 0.035 13.4 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 Septin AAA_18 PF13238.6 EJP66630.1 - 0.036 14.6 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJP66630.1 - 0.049 14.0 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF3052 PF11253.8 EJP66630.1 - 0.053 13.4 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) DUF815 PF05673.13 EJP66630.1 - 0.1 11.7 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_10 PF14788.6 EJP66630.1 - 0.12 12.3 1.8 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 EF hand AAA PF00004.29 EJP66630.1 - 0.13 12.7 0.0 5.4 7.5 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EJP66630.1 - 0.14 11.8 0.0 18 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MCM PF00493.23 EJP66630.1 - 0.2 10.8 0.0 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain EF-hand_8 PF13833.6 EJP66630.1 - 1 9.2 4.7 9.9 6.1 0.8 2.6 2 0 0 2 2 2 0 EF-hand domain pair Pox_MCEL PF03291.16 EJP66631.1 - 3.8e-68 230.1 0.0 2.8e-46 158.2 0.0 2.3 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 EJP66631.1 - 8.7e-10 39.2 0.0 0.00024 21.7 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EJP66631.1 - 2e-09 38.1 0.1 0.0008 20.1 0.0 3.0 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EJP66631.1 - 2.4e-07 30.6 0.0 0.00014 21.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EJP66631.1 - 8.2e-07 29.0 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP66631.1 - 9.4e-07 29.4 0.0 0.05 14.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Raftlin PF15250.6 EJP66631.1 - 0.00034 19.5 5.4 0.00042 19.2 0.1 2.0 2 0 0 2 2 2 1 Raftlin NNMT_PNMT_TEMT PF01234.17 EJP66631.1 - 0.005 16.1 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 EJP66631.1 - 0.21 10.5 0.0 0.38 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Sin_N PF04801.13 EJP66631.1 - 0.79 8.9 4.1 0.34 10.1 0.1 1.9 2 0 0 2 2 2 0 Sin-like protein conserved region DDRGK PF09756.9 EJP66631.1 - 5 6.7 15.1 5.4 6.6 0.7 2.5 2 0 0 2 2 2 0 DDRGK domain RPN7 PF10602.9 EJP66632.1 - 5.1e-57 192.4 1.4 5.9e-57 192.2 0.4 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EJP66632.1 - 1.9e-14 54.0 0.0 5.4e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain Aminotran_1_2 PF00155.21 EJP66633.1 - 2.8e-39 135.4 0.0 3.8e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Fungal_trans PF04082.18 EJP66634.1 - 4.4e-12 45.6 1.2 8.4e-12 44.7 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66634.1 - 2.1e-07 30.9 8.1 4.1e-07 30.0 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FTR1 PF03239.14 EJP66635.1 - 4e-81 272.5 8.7 4.9e-81 272.2 8.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family FtsX PF02687.21 EJP66635.1 - 0.0081 16.6 2.3 0.0081 16.6 2.3 3.4 3 1 0 3 3 3 1 FtsX-like permease family Cu-oxidase_3 PF07732.15 EJP66636.1 - 3.7e-45 152.8 4.9 2.2e-42 143.9 0.4 4.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP66636.1 - 3.2e-43 146.8 5.2 1.7e-38 131.4 1.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EJP66636.1 - 1.5e-36 125.9 0.4 7.2e-34 117.2 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EJP66636.1 - 0.0017 18.4 0.0 3.5 7.8 0.0 4.0 4 1 0 4 4 4 1 Cupredoxin-like domain Tetraspanin PF00335.20 EJP66637.1 - 2.5e-05 24.1 0.0 5.8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Tetraspanin family ABC2_membrane_5 PF13346.6 EJP66637.1 - 0.77 9.3 6.4 0.27 10.8 3.5 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein DEAD PF00270.29 EJP66638.1 - 1.2e-32 113.1 0.0 6.7e-16 58.6 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP66638.1 - 9.1e-19 67.8 0.0 2.6e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP66638.1 - 1.1e-06 28.7 0.0 1.1e-06 28.7 0.0 2.8 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit BUD22 PF09073.10 EJP66638.1 - 0.004 16.6 13.2 0.004 16.6 13.2 2.8 2 1 0 2 2 2 1 BUD22 Macoilin PF09726.9 EJP66638.1 - 0.073 11.6 26.0 0.14 10.7 10.7 2.2 2 0 0 2 2 2 0 Macoilin family SSP160 PF06933.11 EJP66638.1 - 0.3 9.2 9.7 0.71 8.0 9.7 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TEX15 PF15326.6 EJP66638.1 - 7.9 6.1 10.3 21 4.7 10.3 1.7 1 0 0 1 1 1 0 Testis expressed sequence 15 PIGA PF08288.12 EJP66639.1 - 1.5e-47 160.1 2.0 5.1e-47 158.4 0.6 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 EJP66639.1 - 5.8e-27 94.3 0.0 9.7e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EJP66639.1 - 1.5e-26 93.4 0.1 2.2e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EJP66639.1 - 7.2e-23 81.5 0.1 1.7e-22 80.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EJP66639.1 - 4.7e-10 40.1 0.0 7.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EJP66639.1 - 0.00061 20.1 0.0 0.0057 17.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EJP66639.1 - 0.0039 17.2 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Bromodomain PF00439.25 EJP66640.1 - 1.6e-05 24.9 0.0 6.1e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Bromodomain SPC12 PF06645.13 EJP66641.1 - 1.5 9.0 6.2 0.33 11.1 2.2 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF1616 PF07760.11 EJP66641.1 - 6.3 6.1 5.7 8.3 5.7 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) WD40 PF00400.32 EJP66642.1 - 3.6e-11 43.4 16.7 0.003 18.3 0.1 8.4 9 0 0 9 9 9 3 WD domain, G-beta repeat WD40_like PF17005.5 EJP66642.1 - 0.0011 18.4 1.4 0.037 13.4 0.2 3.1 4 0 0 4 4 4 1 WD40-like domain ANAPC4_WD40 PF12894.7 EJP66642.1 - 0.0037 17.5 0.7 10 6.5 0.0 5.2 5 2 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Phage_CI_repr PF07022.13 EJP66642.1 - 0.1 12.7 0.1 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain Aldedh PF00171.22 EJP66643.1 - 4.6e-183 609.0 0.8 5.2e-183 608.8 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Rgp1 PF08737.10 EJP66644.1 - 5.9e-156 519.8 0.0 1.6e-155 518.4 0.0 1.7 2 0 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 EJP66644.1 - 0.00081 19.9 0.0 0.096 13.1 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EJP66644.1 - 0.0054 16.8 0.1 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Alpha_kinase PF02816.18 EJP66645.1 - 1.2e-47 162.4 0.0 1.9e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 EJP66645.1 - 2.3e-11 44.3 0.0 6.7e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EJP66645.1 - 0.0014 18.9 0.1 0.0059 16.9 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EJP66645.1 - 0.053 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Ank_2 PF12796.7 EJP66646.1 - 1.7e-12 47.7 9.2 0.006 17.1 0.0 10.1 7 3 4 12 12 12 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP66646.1 - 1.1e-06 28.5 14.2 0.76 10.5 0.0 12.6 16 0 0 16 16 16 1 Ankyrin repeat Ank_5 PF13857.6 EJP66646.1 - 0.00037 20.7 2.3 1.5e+02 2.9 0.0 6.5 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EJP66646.1 - 0.013 16.0 10.9 5.7 7.7 0.0 8.8 10 1 1 11 11 11 0 Ankyrin repeats (many copies) Ank PF00023.30 EJP66646.1 - 2.9 8.5 15.7 27 5.4 0.0 8.6 11 0 0 11 11 11 0 Ankyrin repeat NAM-associated PF14303.6 EJP66647.1 - 0.12 13.0 3.3 0.19 12.4 3.3 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4698 PF15769.5 EJP66647.1 - 0.26 10.3 3.3 0.29 10.1 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Rpr2 PF04032.16 EJP66648.1 - 9.3e-13 48.3 2.5 9.3e-13 48.3 2.5 1.8 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 EJP66648.1 - 0.1 12.5 3.0 0.73 9.8 0.5 2.6 2 0 0 2 2 2 0 Nudix N-terminal DUF866 PF05907.13 EJP66649.1 - 2.7e-51 173.6 0.2 4.4e-51 172.9 0.2 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PPR_1 PF12854.7 EJP66650.1 - 0.0093 15.6 1.0 0.04 13.6 0.2 2.4 1 1 1 2 2 2 1 PPR repeat PPR_2 PF13041.6 EJP66650.1 - 0.067 13.4 0.3 0.86 9.8 0.1 2.9 3 1 0 3 3 3 0 PPR repeat family GDPD PF03009.17 EJP66651.1 - 7.3e-71 238.9 0.0 1.3e-70 238.1 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EJP66651.1 - 2.2e-34 117.9 0.0 7.3e-15 55.3 0.0 4.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP66651.1 - 2.1e-23 82.4 1.5 3.3e-08 33.9 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP66651.1 - 1.9e-19 69.5 0.2 4.2e-06 26.9 0.1 5.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.19 EJP66651.1 - 2.9e-18 67.0 9.0 1.1e-10 42.0 0.1 4.0 4 1 1 5 5 5 3 SPX domain Ank_3 PF13606.6 EJP66651.1 - 1.7e-14 52.5 0.8 0.0034 17.7 0.0 7.1 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 EJP66651.1 - 2.9e-12 46.4 5.3 0.0026 18.1 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat Env-gp36 PF09590.10 EJP66651.1 - 0.2 10.0 0.0 0.31 9.4 0.0 1.2 1 0 0 1 1 1 0 Lentivirus surface glycoprotein zf-ZPR1 PF03367.13 EJP66652.1 - 1.3e-110 366.3 0.0 4.8e-55 185.8 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain tRNA_int_end_N2 PF12928.7 EJP66654.1 - 7.5e-24 83.7 0.1 1.5e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Arrestin_C PF02752.22 EJP66655.1 - 2.6e-16 60.3 0.0 1.6e-15 57.7 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 EJP66656.1 - 1.3e-44 152.3 0.0 1.4e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.17 EJP66657.1 - 1.9e-28 98.9 0.9 3.9e-28 97.9 0.9 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Tmemb_cc2 PF10267.9 EJP66657.1 - 0.45 9.6 5.8 0.062 12.4 1.5 1.7 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Pex19 PF04614.12 EJP66657.1 - 0.6 9.8 8.0 0.082 12.7 0.5 2.8 3 0 0 3 3 3 0 Pex19 protein family ORC6 PF05460.13 EJP66657.1 - 2.8 7.1 8.9 0.1 11.9 1.6 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Pro_isomerase PF00160.21 EJP66658.1 - 1.8e-42 145.3 0.0 5.4e-42 143.8 0.0 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 EJP66658.1 - 0.00038 20.9 0.7 0.00038 20.9 0.7 4.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) XAP5 PF04921.14 EJP66658.1 - 0.98 9.2 13.9 0.028 14.2 4.6 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator ORC6 PF05460.13 EJP66659.1 - 3.7e-36 125.1 0.2 8.4e-33 114.1 0.0 2.0 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) adh_short_C2 PF13561.6 EJP66660.1 - 1.8e-57 194.6 4.9 2.1e-57 194.4 4.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP66660.1 - 1.6e-45 155.0 3.1 1.9e-45 154.7 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP66660.1 - 3.3e-10 40.2 0.7 9.6e-10 38.7 0.7 1.6 1 1 0 1 1 1 1 KR domain Ribosomal_S11 PF00411.19 EJP66660.1 - 0.067 13.6 1.5 0.21 12.0 0.8 2.1 2 0 0 2 2 2 0 Ribosomal protein S11 Adeno_E3_CR2 PF02439.15 EJP66661.1 - 0.02 14.7 0.4 0.038 13.8 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Presenilin PF01080.17 EJP66661.1 - 0.19 10.4 3.4 0.33 9.7 3.4 1.3 1 0 0 1 1 1 0 Presenilin Miga PF10265.9 EJP66661.1 - 1.4 7.8 5.5 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Mitoguardin CCDC84 PF14968.6 EJP66661.1 - 4.8 6.7 5.3 7.1 6.2 5.3 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 Epimerase PF01370.21 EJP66662.1 - 2.8e-19 69.5 0.0 4e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EJP66662.1 - 1.5e-10 40.7 0.0 2.2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EJP66662.1 - 7.1e-10 38.4 0.0 9.9e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EJP66662.1 - 2.7e-08 33.6 0.1 7.9e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EJP66662.1 - 6.2e-08 32.7 0.7 1.4e-07 31.6 0.2 1.8 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EJP66662.1 - 4.8e-05 23.4 0.1 7.6e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EJP66662.1 - 0.0002 21.0 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EJP66662.1 - 0.0013 18.2 0.1 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EJP66662.1 - 0.002 17.3 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 EJP66662.1 - 0.0026 18.3 0.0 0.0088 16.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Peptidase_M41 PF01434.18 EJP66663.1 - 2.6e-54 184.0 2.2 2.6e-54 184.0 2.2 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EJP66663.1 - 5e-43 146.7 0.0 1.1e-42 145.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP66663.1 - 6.4e-08 32.3 0.1 1.3e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EJP66663.1 - 8e-06 25.9 0.0 3.3e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EJP66663.1 - 3e-05 24.5 1.7 0.0046 17.3 0.1 2.9 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.13 EJP66663.1 - 4.6e-05 22.8 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EJP66663.1 - 0.00012 22.4 0.0 0.054 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EJP66663.1 - 0.0004 20.2 0.0 0.00084 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EJP66663.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EJP66663.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EJP66663.1 - 0.016 14.6 0.1 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EJP66663.1 - 0.016 14.7 0.5 1.2 8.7 0.2 2.6 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 EJP66663.1 - 0.031 14.4 0.0 0.092 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EJP66663.1 - 0.035 13.6 0.3 0.19 11.2 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EJP66663.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EJP66663.1 - 0.067 13.6 0.7 0.41 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.27 EJP66663.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Zeta_toxin PF06414.12 EJP66663.1 - 0.094 12.0 2.5 0.81 8.9 0.5 2.5 1 1 1 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EJP66663.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EJP66663.1 - 0.11 12.2 0.0 0.58 9.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EJP66663.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EJP66663.1 - 0.13 12.2 0.6 1.7 8.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain zf-C2H2 PF00096.26 EJP66664.1 - 9.2e-20 69.9 30.1 3.9e-06 27.0 0.1 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP66664.1 - 1.3e-18 66.4 27.7 2.3e-06 27.8 0.8 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP66664.1 - 6.5e-10 39.0 26.8 0.0095 16.7 0.9 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP66664.1 - 0.00017 21.8 2.8 0.53 10.6 0.4 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EJP66664.1 - 0.0094 16.2 9.0 1.2 9.5 6.4 2.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 EJP66664.1 - 0.015 15.0 2.2 0.015 15.0 2.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 EJP66664.1 - 0.023 15.1 0.5 0.023 15.1 0.5 4.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type CBM9_2 PF16011.5 EJP66664.1 - 0.03 14.0 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding family 9 zf-TRAF PF02176.18 EJP66664.1 - 0.038 14.7 1.4 0.038 14.7 1.4 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 EJP66664.1 - 0.36 11.0 0.0 0.36 11.0 0.0 3.3 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 EJP66664.1 - 5.4 7.7 25.7 5.3 7.7 0.3 5.5 4 1 2 6 6 5 0 FOXP coiled-coil domain LapA_dom PF06305.11 EJP66667.1 - 6.9 6.6 5.0 11 6.0 1.8 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EF-hand_6 PF13405.6 EJP66669.1 - 4.8e-08 32.3 1.3 0.0029 17.4 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EJP66669.1 - 3.9e-07 30.4 2.1 3.9e-07 30.4 2.1 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EJP66669.1 - 1.6e-05 24.2 0.2 0.00019 20.8 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 EJP66669.1 - 0.00023 20.5 0.4 0.007 15.8 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EJP66669.1 - 0.002 18.0 0.5 0.0082 16.0 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EJP66669.1 - 0.05 13.9 1.4 0.18 12.1 0.1 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Met_10 PF02475.16 EJP66670.1 - 6e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Metallophos PF00149.28 EJP66671.1 - 1.9e-32 113.4 0.0 1e-27 98.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EJP66671.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EJP66671.1 - 0.046 14.2 0.1 0.12 12.9 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Smg4_UPF3 PF03467.15 EJP66672.1 - 1.5e-45 155.3 0.0 1.5e-45 155.3 0.0 3.4 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 EJP66672.1 - 1.7e-05 24.6 0.0 0.00012 21.9 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Putative_PNPOx PF01243.20 EJP66673.1 - 0.0052 16.9 0.0 0.02 15.1 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GAS PF13851.6 EJP66675.1 - 1.5e-05 24.4 8.2 0.0034 16.8 0.7 3.0 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EJP66675.1 - 0.00013 22.0 11.9 0.0079 16.2 0.5 3.0 2 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 EJP66675.1 - 0.00026 21.0 2.9 0.014 15.5 0.0 3.0 3 0 0 3 3 3 1 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 EJP66675.1 - 0.0021 17.0 5.2 0.014 14.3 2.6 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein YabA PF06156.13 EJP66675.1 - 0.0027 18.3 4.2 0.17 12.5 4.2 2.8 1 1 0 1 1 1 1 Initiation control protein YabA Phage_GP20 PF06810.11 EJP66675.1 - 0.0028 17.5 4.0 1.8 8.3 0.1 3.1 2 1 1 3 3 3 1 Phage minor structural protein GP20 FAM184 PF15665.5 EJP66675.1 - 0.0028 17.5 1.5 0.006 16.4 1.5 1.5 1 1 0 1 1 1 1 Family with sequence similarity 184, A and B Cep57_MT_bd PF06657.13 EJP66675.1 - 0.0053 17.2 4.8 0.16 12.5 0.2 3.5 1 1 3 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Seryl_tRNA_N PF02403.22 EJP66675.1 - 0.0088 16.3 6.3 0.97 9.7 0.2 3.1 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 EJP66675.1 - 0.01 15.8 9.8 3.2 7.8 0.0 4.1 3 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CAGE1 PF15066.6 EJP66675.1 - 0.011 14.5 0.9 0.011 14.5 0.9 1.8 2 1 0 2 2 2 0 Cancer-associated gene protein 1 family CCDC144C PF14915.6 EJP66675.1 - 0.011 14.9 10.1 0.023 13.9 3.5 2.8 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region Cnn_1N PF07989.11 EJP66675.1 - 0.012 15.8 9.5 2.1 8.5 1.2 3.6 2 2 0 3 3 3 0 Centrosomin N-terminal motif 1 Herpes_BLRF2 PF05812.12 EJP66675.1 - 0.013 15.6 0.3 0.054 13.6 0.2 2.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein SlyX PF04102.12 EJP66675.1 - 0.025 15.2 11.9 2.4 8.9 0.5 3.7 2 2 1 3 3 3 0 SlyX DUF2935 PF11155.8 EJP66675.1 - 0.03 14.7 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) ATG16 PF08614.11 EJP66675.1 - 0.031 14.5 8.1 0.13 12.5 2.0 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mod_r PF07200.13 EJP66675.1 - 0.035 14.2 3.9 0.11 12.6 0.5 2.3 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FliJ PF02050.16 EJP66675.1 - 0.042 14.1 6.3 0.42 10.8 1.1 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein bZIP_1 PF00170.21 EJP66675.1 - 0.045 13.8 12.6 0.83 9.8 0.1 3.8 3 1 1 4 4 4 0 bZIP transcription factor Atg14 PF10186.9 EJP66675.1 - 0.048 12.7 6.7 0.027 13.6 1.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 EJP66675.1 - 0.049 13.2 8.1 0.4 10.2 8.1 2.3 1 1 0 1 1 1 0 Intermediate filament protein HAP1_N PF04849.13 EJP66675.1 - 0.051 12.8 11.6 0.012 14.8 5.7 1.9 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 EJP66675.1 - 0.058 13.6 6.9 0.038 14.2 1.8 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.19 EJP66675.1 - 0.098 10.4 8.3 0.29 8.9 8.3 1.7 1 1 0 1 1 1 0 Myosin tail Rho_Binding PF08912.11 EJP66675.1 - 0.13 13.1 8.0 4 8.3 0.2 3.6 3 1 1 4 4 3 0 Rho Binding DUF2730 PF10805.8 EJP66675.1 - 0.13 12.3 1.6 1 9.5 0.0 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2730) Apolipoprotein PF01442.18 EJP66675.1 - 0.14 12.1 5.4 4.5 7.1 5.3 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Swi5 PF07061.11 EJP66675.1 - 0.15 12.2 5.0 0.77 9.9 0.3 3.3 3 1 1 4 4 4 0 Swi5 DUF1664 PF07889.12 EJP66675.1 - 0.16 12.0 3.1 6.3 6.8 0.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 EJP66675.1 - 0.19 11.8 9.1 14 5.7 9.1 2.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 EJP66675.1 - 0.2 11.6 10.4 4.1 7.4 0.1 3.7 3 1 0 3 3 3 0 Prefoldin subunit KLRAQ PF10205.9 EJP66675.1 - 0.21 11.9 7.1 11 6.4 0.4 3.5 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF3450 PF11932.8 EJP66675.1 - 0.25 10.6 5.9 0.3 10.4 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF3138 PF11336.8 EJP66675.1 - 0.25 9.9 0.0 2.3 6.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) BST2 PF16716.5 EJP66675.1 - 0.26 11.9 10.8 1.3 9.6 0.6 3.7 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF641 PF04859.12 EJP66675.1 - 0.26 11.6 7.6 8 6.8 0.2 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) FUSC PF04632.12 EJP66675.1 - 0.28 9.7 0.7 0.34 9.4 0.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fungal_TACC PF12709.7 EJP66675.1 - 0.31 11.5 7.2 9.8 6.7 0.0 3.8 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins PI3K_P85_iSH2 PF16454.5 EJP66675.1 - 0.32 10.6 8.4 0.85 9.2 0.5 2.9 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Taxilin PF09728.9 EJP66675.1 - 0.42 9.8 5.2 2.1 7.4 0.0 2.7 2 1 0 2 2 2 0 Myosin-like coiled-coil protein Lzipper-MIP1 PF14389.6 EJP66675.1 - 0.43 10.9 10.6 1.6 9.1 2.9 3.4 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 GrpE PF01025.19 EJP66675.1 - 0.45 10.1 4.6 47 3.6 4.6 2.8 1 1 0 1 1 1 0 GrpE FlaC_arch PF05377.11 EJP66675.1 - 0.46 10.9 5.5 10 6.6 0.1 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 EJP66675.1 - 0.46 10.5 3.1 6.1 6.9 0.4 2.7 2 1 1 3 3 3 0 Laminin Domain II HMMR_N PF15905.5 EJP66675.1 - 0.56 9.6 8.2 2.6 7.4 5.4 2.5 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal KASH_CCD PF14662.6 EJP66675.1 - 0.57 10.0 11.8 13 5.5 11.8 2.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4763 PF15960.5 EJP66675.1 - 0.7 9.2 10.3 0.17 11.1 4.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) MscS_porin PF12795.7 EJP66675.1 - 0.78 9.2 6.4 0.49 9.9 0.9 2.3 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain ZapB PF06005.12 EJP66675.1 - 0.8 10.2 12.9 0.1 13.0 3.3 3.0 3 1 0 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 EJP66675.1 - 0.83 9.5 13.9 20 5.1 0.1 4.1 3 1 1 4 4 4 0 Septum formation initiator DUF724 PF05266.14 EJP66675.1 - 0.92 9.3 4.2 3.1 7.6 1.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) HALZ PF02183.18 EJP66675.1 - 1.2 9.4 7.5 0.97 9.7 0.2 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4515 PF14988.6 EJP66675.1 - 1.3 8.9 12.3 2.1 8.2 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4515) SIKE PF05769.11 EJP66675.1 - 1.4 8.9 8.5 3.1 7.7 0.5 3.1 3 1 0 3 3 3 0 SIKE family Snapin_Pallidin PF14712.6 EJP66675.1 - 1.4 9.4 6.8 2 8.9 0.1 3.0 2 1 0 2 2 2 0 Snapin/Pallidin GIT_CC PF16559.5 EJP66675.1 - 1.6 8.6 6.8 2.8 7.9 1.5 3.4 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ADIP PF11559.8 EJP66675.1 - 2.1 8.4 11.4 1.4 9.0 0.4 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 EJP66675.1 - 2.6 7.7 10.8 8.1 6.1 0.6 3.1 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 PKcGMP_CC PF16808.5 EJP66675.1 - 3.9 7.4 15.0 0.54 10.2 0.2 4.1 4 1 1 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tropomyosin_1 PF12718.7 EJP66675.1 - 6.9 6.8 13.1 25 5.0 6.8 3.0 1 1 1 2 2 2 0 Tropomyosin like Spc24 PF08286.11 EJP66675.1 - 7.4 6.9 10.2 77 3.6 0.1 3.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 EJP66675.1 - 8.2 6.5 12.4 26 4.9 5.9 3.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein EMC1_C PF07774.13 EJP66676.1 - 6.1e-71 238.5 0.0 9e-71 237.9 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EJP66676.1 - 1.1e-19 71.0 19.6 5.8e-15 55.5 7.7 3.6 2 2 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 EJP66676.1 - 8e-06 25.5 2.5 0.54 10.3 0.0 4.6 4 0 0 4 4 4 2 PQQ enzyme repeat Peptidase_S8 PF00082.22 EJP66677.1 - 3.6e-31 108.5 9.0 6.1e-31 107.8 9.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJP66677.1 - 6.7e-10 39.5 0.3 2.7e-09 37.6 0.3 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 GMC_oxred_N PF00732.19 EJP66678.1 - 9.1e-35 120.5 0.0 1.4e-30 106.7 0.0 3.2 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP66678.1 - 2.4e-31 109.2 0.1 3.9e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EJP66678.1 - 0.00078 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP66678.1 - 0.0021 18.2 0.1 0.0073 16.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP66678.1 - 0.0024 17.0 0.1 0.01 14.9 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EJP66678.1 - 0.0024 17.2 0.1 1.1 8.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EJP66678.1 - 0.053 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_16 PF00722.21 EJP66679.1 - 1.1e-43 148.7 1.0 1.8e-43 148.1 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2457 PF10446.9 EJP66679.1 - 1.5 7.8 5.4 2.4 7.2 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4472 PF14739.6 EJP66680.1 - 0.0074 17.0 1.0 0.012 16.3 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) Laminin_II PF06009.12 EJP66680.1 - 0.032 14.3 0.6 0.045 13.8 0.6 1.2 1 0 0 1 1 1 0 Laminin Domain II T3SSipB PF16535.5 EJP66680.1 - 0.18 12.3 1.9 0.3 11.6 1.9 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB IGF2_C PF08365.11 EJP66680.1 - 6.6 6.8 10.0 3.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide Ras PF00071.22 EJP66681.1 - 1.4e-53 180.8 0.0 1.9e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP66681.1 - 3.1e-21 75.8 0.0 6.6e-21 74.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP66681.1 - 2.3e-09 36.9 0.0 4.6e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EJP66681.1 - 0.0032 16.7 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EJP66681.1 - 0.0079 15.6 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EJP66681.1 - 0.0095 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EJP66681.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EJP66681.1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EJP66681.1 - 0.12 12.1 0.1 2.5 7.8 0.1 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CWC25 PF12542.8 EJP66682.1 - 1.7e-27 96.3 1.4 1.7e-27 96.3 1.4 2.2 1 1 1 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.9 EJP66682.1 - 3.5e-13 49.5 1.7 3.5e-13 49.5 1.7 2.6 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Endotoxin_C2 PF18449.1 EJP66682.1 - 0.022 15.1 0.7 2.2 8.7 0.1 2.6 2 0 0 2 2 2 0 Delta endotoxin Ribosomal_S14 PF00253.21 EJP66683.1 - 1.1e-21 76.3 0.9 1.1e-21 76.3 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Glyco_hydro_3_C PF01915.22 EJP66684.1 - 8.5e-44 149.9 0.0 1.6e-43 149.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EJP66684.1 - 4.6e-42 144.5 0.0 7.7e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EJP66684.1 - 3.5e-27 94.3 0.1 6.6e-27 93.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 EJP66686.1 - 4.8e-37 127.7 38.9 9.5e-34 116.9 16.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP66686.1 - 5.5e-09 35.4 3.5 1.3e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EJP66686.1 - 0.00091 18.2 2.0 0.00091 18.2 2.0 2.2 2 0 0 2 2 2 1 MFS_1 like family CENP-B_dimeris PF09026.10 EJP66686.1 - 0.0014 19.0 0.6 0.0035 17.7 0.6 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF3246 PF11596.8 EJP66686.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 EJP66686.1 - 3.8 7.2 4.5 7.1 6.3 4.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PALP PF00291.25 EJP66687.1 - 7.1e-40 137.3 0.4 8.5e-40 137.0 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.18 EJP66687.1 - 0.048 12.9 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 LytB protein HTH_AsnC-type PF13404.6 EJP66687.1 - 0.071 13.0 0.2 0.76 9.7 0.1 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PAP_assoc PF03828.19 EJP66688.1 - 1.7e-17 63.4 0.3 4.6e-17 62.0 0.3 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EJP66688.1 - 2.1e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain F-box_5 PF18511.1 EJP66689.1 - 0.093 12.3 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 F-box SLC35F PF06027.12 EJP66690.1 - 1.9e-101 339.5 20.4 2.5e-101 339.2 20.4 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EJP66690.1 - 1.4e-11 43.9 5.3 2.2e-11 43.3 5.3 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EJP66690.1 - 9.8e-08 32.3 34.7 0.00045 20.4 12.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family An_peroxidase PF03098.15 EJP66691.1 - 3e-36 125.1 0.4 2.3e-12 46.3 0.9 4.2 2 1 1 3 3 3 3 Animal haem peroxidase p450 PF00067.22 EJP66691.1 - 1.2e-07 30.9 0.0 3.4e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 VKG_Carbox PF05090.14 EJP66691.1 - 0.17 10.7 0.1 0.76 8.5 0.0 1.8 2 0 0 2 2 2 0 Vitamin K-dependent gamma-carboxylase Metallophos PF00149.28 EJP66692.1 - 5e-11 43.5 1.9 9.2e-11 42.6 1.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EJP66692.1 - 0.0011 19.2 0.0 0.016 15.4 0.0 2.3 1 1 0 2 2 2 1 5'-nucleotidase, C-terminal domain adh_short PF00106.25 EJP66693.1 - 9e-38 129.7 0.1 1.3e-37 129.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP66693.1 - 1.1e-25 90.5 0.8 2.2e-25 89.6 0.8 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EJP66693.1 - 2.3e-07 30.9 1.3 3.5e-07 30.3 1.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EJP66693.1 - 0.0021 18.0 0.4 0.0043 17.0 0.4 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP66693.1 - 0.0028 17.1 0.4 0.0039 16.7 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EJP66693.1 - 0.032 13.8 0.3 0.045 13.3 0.3 1.2 1 0 0 1 1 1 0 NmrA-like family TLP1_add_C PF18313.1 EJP66693.1 - 0.075 13.0 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain DUF1776 PF08643.10 EJP66693.1 - 0.24 10.7 0.0 1.7 8.0 0.0 2.1 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) AA_permease PF00324.21 EJP66694.1 - 3e-119 398.7 26.9 3.7e-119 398.4 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP66694.1 - 6.6e-34 117.5 31.2 7.8e-34 117.2 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease EMP70 PF02990.16 EJP66694.1 - 7.3 5.1 11.1 0.25 10.0 1.7 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 Pkinase PF00069.25 EJP66695.1 - 8.7e-39 133.5 0.1 2e-38 132.3 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66695.1 - 2.1e-20 73.1 0.0 3.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP66695.1 - 5.4e-05 22.6 0.2 0.00012 21.5 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP66695.1 - 0.0029 17.6 0.3 0.0073 16.3 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EJP66695.1 - 0.081 11.7 0.2 0.15 10.8 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Nucleoporin_FG PF13634.6 EJP66696.1 - 0.33 11.8 6.4 1.4 9.8 3.5 3.0 2 1 0 2 2 2 0 Nucleoporin FG repeat region Tim17 PF02466.19 EJP66697.1 - 2.7e-32 111.5 7.0 3.6e-32 111.0 7.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Globin PF00042.22 EJP66698.1 - 1.6e-08 35.0 0.0 3.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 EJP66698.1 - 5.6e-08 33.4 0.0 9.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EJP66698.1 - 7.7e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 EJP66698.1 - 0.0059 16.5 0.1 0.0096 15.8 0.1 1.4 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 EJP66698.1 - 0.03 14.4 0.2 1.1 9.4 0.1 2.7 2 1 0 3 3 3 0 Ferric reductase NAD binding domain DUF356 PF04009.12 EJP66698.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF356) Glyco_hydro_72 PF03198.14 EJP66700.1 - 7.1e-124 413.2 2.4 8.7e-124 412.8 2.4 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EJP66700.1 - 2.2e-06 27.3 0.1 2e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Oxysterol_BP PF01237.18 EJP66701.1 - 2.3e-110 368.9 0.0 4e-110 368.2 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EJP66701.1 - 4.1e-36 123.1 0.1 1e-35 121.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EJP66701.1 - 7.9e-07 29.5 0.0 1.8e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PH domain GOLD_2 PF13897.6 EJP66701.1 - 0.0082 16.6 1.9 0.086 13.3 0.0 2.5 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking PH_17 PF18012.1 EJP66701.1 - 0.14 11.9 0.2 0.79 9.5 0.1 2.2 2 0 0 2 2 2 0 PH domain Helo_like_N PF17111.5 EJP66703.1 - 0.012 15.0 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Peptidase_S8 PF00082.22 EJP66704.1 - 1.9e-37 129.1 3.1 1.9e-37 129.1 3.1 1.7 2 0 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 EJP66704.1 - 2.3e-12 47.6 0.0 4.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 EJP66704.1 - 0.03 14.2 0.0 0.15 11.9 0.0 2.3 1 0 0 1 1 1 0 FlgD Ig-like domain PDEase_II PF02112.15 EJP66705.1 - 2.3e-55 188.0 0.0 1e-22 80.7 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 EJP66705.1 - 0.024 14.7 0.2 0.067 13.2 0.2 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily AMP-binding PF00501.28 EJP66707.1 - 4.4e-68 229.8 0.0 3.7e-38 131.2 0.0 3.6 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 EJP66707.1 - 6.8e-06 26.9 0.0 1.7e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 EJP66707.1 - 0.016 15.2 0.3 0.033 14.2 0.3 1.5 1 0 0 1 1 1 0 Gas vesicle protein G SKG6 PF08693.10 EJP66708.1 - 2.3e-06 26.9 0.8 4.3e-06 26.0 0.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sporozoite_P67 PF05642.11 EJP66708.1 - 0.14 10.2 21.1 0.18 9.9 21.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 EJP66708.1 - 0.26 11.0 4.5 0.51 10.0 4.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 EJP66708.1 - 0.32 10.5 1.9 0.5 9.9 1.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 EJP66708.1 - 0.44 11.0 7.3 0.98 9.9 7.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EJP66708.1 - 0.66 9.2 4.4 1 8.6 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2183 PF09949.9 EJP66709.1 - 1.2e-30 105.8 0.0 3.4e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EJP66709.1 - 0.0031 17.0 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DEAD PF00270.29 EJP66710.1 - 1.7e-45 154.9 0.1 1.7e-45 154.9 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP66710.1 - 5.8e-29 100.7 0.1 3.4e-28 98.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EJP66710.1 - 0.032 13.0 0.4 0.33 9.7 0.0 2.7 1 1 2 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 EB1 PF03271.17 EJP66711.1 - 1.3e-16 60.6 1.9 2.9e-16 59.4 1.9 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EJP66711.1 - 2.1e-07 31.1 1.0 4e-07 30.2 1.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 EJP66711.1 - 0.017 15.2 0.2 0.03 14.4 0.2 1.5 1 1 0 1 1 1 0 CH-like domain in sperm protein BTV_NS2 PF04514.12 EJP66711.1 - 0.079 11.8 0.2 0.13 11.1 0.1 1.4 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 PX PF00787.24 EJP66712.1 - 4.1e-15 55.7 0.0 8.5e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF16 PF01519.16 EJP66712.1 - 2.3 8.8 8.6 5.9 7.4 7.4 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 ERM PF00769.19 EJP66713.1 - 0.041 13.7 26.5 0.06 13.2 26.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Amidase PF01425.21 EJP66714.1 - 7.6e-35 120.7 0.8 2.4e-34 119.1 0.4 1.8 2 0 0 2 2 2 1 Amidase WD40 PF00400.32 EJP66715.1 - 8e-05 23.3 1.1 3.3 8.7 0.0 4.3 3 1 1 4 4 4 2 WD domain, G-beta repeat PD40 PF07676.12 EJP66715.1 - 0.024 14.6 0.1 4.8 7.2 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 EJP66715.1 - 0.09 11.8 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Macro PF01661.21 EJP66716.1 - 4.5e-12 46.0 0.0 6.2e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Macro domain WD40 PF00400.32 EJP66718.1 - 2.2e-28 97.9 18.0 4.4e-06 27.3 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 EJP66718.1 - 2.5e-09 36.9 0.7 6.2e-09 35.6 0.7 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EJP66718.1 - 2.1e-06 27.9 0.1 0.0024 18.1 0.0 4.3 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EJP66718.1 - 0.0001 22.1 0.1 0.00019 21.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 EJP66718.1 - 0.008 15.8 0.4 0.031 13.9 0.4 1.9 1 1 0 1 1 1 1 PQQ-like domain F-box_4 PF15966.5 EJP66718.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box Nup160 PF11715.8 EJP66718.1 - 0.086 11.5 6.0 2.9 6.4 0.0 4.1 3 2 2 5 5 5 0 Nucleoporin Nup120/160 Pectate_lyase_3 PF12708.7 EJP66720.1 - 1.2e-93 312.9 30.0 4.7e-82 275.0 10.8 3.3 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EJP66720.1 - 2.3e-06 27.2 3.3 0.013 15.1 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase zf-CCCH_2 PF14608.6 EJP66720.1 - 4.8 7.8 5.6 1.7 9.2 0.8 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Scs3p PF10261.9 EJP66721.1 - 2.8e-18 66.3 0.1 2.9e-18 66.3 0.1 1.0 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.9 EJP66722.1 - 6.9e-24 83.8 0.0 1.1e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase Myb_DNA-binding PF00249.31 EJP66723.1 - 0.0032 17.6 1.4 0.0034 17.5 0.1 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Man-6-P_recep PF02157.15 EJP66724.1 - 2e-14 53.3 0.0 3.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EJP66724.1 - 9.7e-13 48.6 0.1 4.4e-12 46.4 0.1 1.9 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EJP66724.1 - 1.3e-08 35.0 0.2 1.2e-05 25.4 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 EJP66725.1 - 9.9e-173 574.8 1.6 1.2e-172 574.5 1.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EJP66725.1 - 0.00032 20.3 2.3 0.00034 20.2 0.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) Glyco_hydro_3_C PF01915.22 EJP66726.1 - 2.2e-39 135.6 0.0 4.7e-39 134.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EJP66726.1 - 7.9e-33 114.2 0.0 1.3e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EJP66726.1 - 9.8e-19 67.3 0.0 1.8e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3346 PF11826.8 EJP66726.1 - 0.22 11.3 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) zf-C2H2_aberr PF17017.5 EJP66727.1 - 0.021 15.0 5.8 0.12 12.5 3.3 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger UPF0052 PF01933.18 EJP66728.1 - 1.7e-62 211.3 0.0 2.1e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Hydrolase_4 PF12146.8 EJP66729.1 - 1.2e-10 41.1 0.0 2.5e-10 40.1 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP66729.1 - 3.2e-09 37.7 5.4 3.2e-09 37.7 5.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP66729.1 - 1.3e-07 31.5 0.3 6.4e-07 29.3 0.4 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 EJP66729.1 - 0.077 12.9 0.0 9.6 6.1 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal RIO1 PF01163.22 EJP66730.1 - 1.2e-68 230.4 0.0 2.8e-68 229.3 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EJP66730.1 - 0.0003 20.8 0.2 0.64 9.9 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EJP66730.1 - 0.028 13.8 4.1 0.039 13.3 0.3 2.6 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 EJP66731.1 - 3.4e-19 68.9 0.6 5.7e-19 68.2 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.19 EJP66732.1 - 2.7e-40 138.6 0.0 4.6e-40 137.8 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP66732.1 - 1.6e-26 93.6 0.0 2.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EJP66732.1 - 3.9e-08 32.8 0.4 0.00048 19.3 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 EJP66732.1 - 2.6e-07 30.6 0.0 1.2e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP66732.1 - 2.9e-06 26.6 0.0 0.00016 20.9 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EJP66732.1 - 6.6e-06 26.3 0.0 4.8e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP66732.1 - 0.0007 18.9 0.0 0.0026 17.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP66732.1 - 0.015 14.6 0.1 0.033 13.4 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EJP66732.1 - 0.067 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EJP66732.1 - 0.075 12.3 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 EJP66732.1 - 0.088 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EJP66732.1 - 0.098 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP66732.1 - 0.14 12.7 0.0 1.2 9.7 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP66732.1 - 0.34 10.9 1.3 1.2 9.1 0.1 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Chromate_transp PF02417.15 EJP66733.1 - 2e-52 177.5 37.7 1.3e-30 106.7 16.1 2.5 3 0 0 3 3 3 2 Chromate transporter Arylsulfotran_2 PF14269.6 EJP66734.1 - 3.9e-42 144.7 8.5 1.3e-41 142.9 8.5 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EJP66734.1 - 2e-13 50.0 5.7 1.5e-11 43.8 5.9 2.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Whirly PF08536.11 EJP66734.1 - 0.074 12.9 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Whirly transcription factor Secretin_N_2 PF07655.13 EJP66734.1 - 1 9.9 11.4 3 8.5 11.4 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.13 EJP66734.1 - 2.5 6.3 4.1 3.7 5.8 4.1 1.1 1 0 0 1 1 1 0 Menin AMP-binding PF00501.28 EJP66735.1 - 4.9e-75 252.7 0.0 1.1e-74 251.5 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EJP66735.1 - 1.9e-59 200.9 0.0 4.1e-59 199.9 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EJP66735.1 - 2e-53 180.7 2.1 5.9e-53 179.2 2.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP66735.1 - 4e-40 137.8 0.2 8.1e-40 136.8 0.2 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP66735.1 - 9.5e-18 64.7 1.9 4e-14 52.9 1.3 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EJP66735.1 - 1.2e-16 60.9 0.1 2.8e-10 40.1 0.0 2.9 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EJP66735.1 - 2.4e-13 50.2 0.0 5.5e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 EJP66735.1 - 7.3e-07 28.6 0.6 0.00038 19.7 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 EJP66735.1 - 4.9e-06 26.5 0.1 0.00012 22.0 0.3 2.5 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EJP66735.1 - 6.2e-05 22.1 0.1 0.061 12.3 0.0 3.0 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EJP66735.1 - 0.001 20.0 0.2 0.0049 17.8 0.2 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 EJP66735.1 - 0.0044 16.2 3.3 0.68 9.0 0.3 3.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein OSK PF17182.4 EJP66735.1 - 0.0054 16.0 0.1 0.0093 15.2 0.1 1.2 1 0 0 1 1 1 1 OSK domain DFP PF04127.15 EJP66735.1 - 0.0084 16.0 1.3 0.03 14.1 1.3 1.9 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 EJP66735.1 - 0.02 14.3 0.1 7.6 5.8 0.1 2.8 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 EJP66735.1 - 0.057 13.1 0.2 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 EJP66735.1 - 0.072 12.4 2.4 0.15 11.4 0.1 2.6 2 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lipase3_N PF03893.16 EJP66735.1 - 0.2 11.7 0.2 0.73 9.9 0.0 1.9 2 0 0 2 2 2 0 Lipase 3 N-terminal region NmrA PF05368.13 EJP66735.1 - 0.69 9.4 2.6 32 4.0 2.4 2.7 2 0 0 2 2 2 0 NmrA-like family AA_permease PF00324.21 EJP66736.1 - 6.5e-135 450.4 48.1 7.7e-135 450.2 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP66736.1 - 6.6e-30 104.3 59.0 1.9e-29 102.8 59.0 1.6 1 1 0 1 1 1 1 Amino acid permease SID-1_RNA_chan PF13965.6 EJP66736.1 - 0.26 9.6 6.4 0.44 8.9 6.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3671 PF12420.8 EJP66736.1 - 6.2 6.9 5.8 25 5.0 4.4 2.7 2 1 0 2 2 2 0 Protein of unknown function AC_N PF16214.5 EJP66736.1 - 9.7 5.2 6.2 20 4.2 6.2 1.5 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Abhydrolase_6 PF12697.7 EJP66739.1 - 5.5e-07 30.4 3.7 8.8e-07 29.7 3.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP66739.1 - 0.0032 16.8 0.3 0.0052 16.1 0.3 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EJP66739.1 - 0.0038 17.2 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EJP66739.1 - 0.033 13.6 0.1 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Sugar_tr PF00083.24 EJP66740.1 - 2.4e-93 313.5 30.4 2.8e-93 313.3 30.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP66740.1 - 2.1e-14 53.3 30.8 2.1e-14 53.3 30.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 EJP66741.1 - 4.5e-17 61.9 26.3 5.2e-09 36.1 5.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP66741.1 - 1.1e-11 44.2 0.1 1.9e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 EJP66741.1 - 7.8 6.3 12.8 1.9 8.3 2.1 3.2 2 1 1 3 3 3 0 Integrin plexin domain SH2 PF00017.24 EJP66742.1 - 0.04 14.0 0.0 1 9.5 0.0 2.1 1 1 1 2 2 2 0 SH2 domain NmrA PF05368.13 EJP66743.1 - 1.2e-24 87.2 0.0 1.6e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP66743.1 - 2.6e-17 63.3 0.1 3.6e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EJP66743.1 - 0.00013 21.5 0.1 0.0011 18.4 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EJP66743.1 - 0.00028 21.1 0.1 0.00059 20.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EJP66743.1 - 0.00074 20.0 0.1 0.0019 18.6 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.18 EJP66744.1 - 1.2e-11 44.2 2.1 1.8e-11 43.6 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66744.1 - 6.6e-07 29.4 9.1 6.6e-07 29.4 9.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 EJP66744.1 - 0.012 16.0 1.7 0.012 16.0 1.7 3.4 2 1 0 2 2 2 0 Zinc-finger double domain MFS_1 PF07690.16 EJP66745.1 - 1.1e-33 116.6 32.4 1.1e-33 116.6 32.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP66745.1 - 6.6e-10 38.4 13.8 4.7e-09 35.6 13.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter LacY_symp PF01306.19 EJP66745.1 - 0.0031 16.3 1.0 0.0031 16.3 1.0 1.9 3 0 0 3 3 3 1 LacY proton/sugar symporter MFS_1_like PF12832.7 EJP66745.1 - 0.0037 16.2 6.2 0.33 9.7 6.2 2.7 1 1 0 1 1 1 1 MFS_1 like family PTR2 PF00854.21 EJP66745.1 - 0.004 16.0 0.0 0.0095 14.8 0.0 1.6 1 0 0 1 1 1 1 POT family TRI12 PF06609.13 EJP66745.1 - 0.0047 15.4 0.9 0.0047 15.4 0.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Bestrophin PF01062.21 EJP66746.1 - 6e-37 127.6 0.0 1.3e-36 126.5 0.0 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PHO4 PF01384.20 EJP66746.1 - 0.024 13.7 0.4 0.086 11.9 0.4 1.8 1 1 0 1 1 1 0 Phosphate transporter family Tagatose_6_P_K PF08013.11 EJP66746.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase MFS_1 PF07690.16 EJP66747.1 - 1.3e-33 116.4 68.1 8.9e-27 93.9 43.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP66747.1 - 2.4e-08 33.3 10.8 2.4e-08 33.3 10.8 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Protocadherin PF08374.11 EJP66747.1 - 3 7.8 5.7 8.9 6.2 1.0 2.2 2 0 0 2 2 2 0 Protocadherin DUF3431 PF11913.8 EJP66748.1 - 5.2e-87 291.1 0.3 6.5e-87 290.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Med22 PF06179.12 EJP66749.1 - 2.6e-19 69.4 0.1 3.1e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PseudoU_synth_1 PF01416.20 EJP66750.1 - 2.8e-11 43.8 0.0 1.4e-09 38.4 0.0 2.7 2 1 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 EJP66750.1 - 0.049 13.5 0.1 0.56 10.0 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) CCDC53 PF10152.9 EJP66750.1 - 0.2 12.1 2.7 0.44 10.9 2.7 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Menin PF05053.13 EJP66750.1 - 2.7 6.3 8.6 0.14 10.5 2.7 1.7 2 0 0 2 2 2 0 Menin CPSF100_C PF13299.6 EJP66750.1 - 3.6 7.8 6.9 0.21 11.8 1.3 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AA_permease_2 PF13520.6 EJP66751.1 - 2.5e-41 141.9 42.5 3e-41 141.6 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP66751.1 - 8.5e-19 67.5 31.9 1.5e-18 66.7 31.9 1.3 1 0 0 1 1 1 1 Amino acid permease SAICAR_synt PF01259.18 EJP66752.1 - 2.7e-88 295.8 0.0 3.4e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Shisa PF13908.6 EJP66753.1 - 0.12 12.6 6.4 0.032 14.5 1.7 2.1 1 1 2 3 3 3 0 Wnt and FGF inhibitory regulator WD40 PF00400.32 EJP66754.1 - 1e-41 140.1 14.8 1.6e-08 35.1 0.1 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 EJP66754.1 - 3e-11 43.0 0.8 5.8e-11 42.1 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP66754.1 - 3.9e-10 39.4 0.3 9.8e-10 38.1 0.3 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EJP66754.1 - 4.5e-10 38.8 2.7 0.2 10.3 0.0 4.2 3 1 1 4 4 4 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EJP66754.1 - 1.9e-08 34.5 0.5 0.071 13.4 0.0 5.5 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EJP66754.1 - 0.0018 18.1 0.1 0.0059 16.5 0.1 1.9 2 0 0 2 2 2 1 F-box PALB2_WD40 PF16756.5 EJP66754.1 - 0.2 10.5 4.7 15 4.4 0.1 3.8 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Mito_carr PF00153.27 EJP66755.1 - 6.5e-67 221.5 1.0 1.5e-21 76.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 EJP66756.1 - 1.3e-35 121.8 0.0 1.1e-19 70.5 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF908 PF06012.12 EJP66757.1 - 0.012 15.0 1.2 0.014 14.8 1.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Ribosomal_S7e PF01251.18 EJP66758.1 - 1.1e-82 276.3 0.4 1.3e-82 276.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.13 EJP66759.1 - 6.5e-179 595.7 4.4 3.7e-175 583.3 4.4 2.4 1 1 0 1 1 1 1 Dynactin p62 family zinc_ribbon_10 PF10058.9 EJP66759.1 - 0.44 10.3 11.3 0.54 10.0 0.0 3.2 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein OrfB_Zn_ribbon PF07282.11 EJP66759.1 - 9.1 6.3 8.1 9.5 6.2 0.1 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Abhydrolase_1 PF00561.20 EJP66762.1 - 2e-22 80.1 0.1 1.4e-17 64.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EJP66762.1 - 5.2e-15 55.4 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF924 PF06041.11 EJP66763.1 - 1.4e-55 188.2 0.0 1.9e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Glyco_hydro_47 PF01532.20 EJP66764.1 - 1.6e-163 544.9 0.0 1.8e-163 544.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 EJP66764.1 - 0.098 11.7 0.0 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Sec16_N PF12935.7 EJP66765.1 - 0.04 14.1 0.2 0.054 13.7 0.2 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Macoilin PF09726.9 EJP66766.1 - 4.8 5.6 8.1 6.3 5.2 8.1 1.1 1 0 0 1 1 1 0 Macoilin family Granulin PF00396.18 EJP66766.1 - 8.4 6.8 15.9 10 6.5 7.0 2.6 1 1 1 2 2 2 0 Granulin Enterotoxin_a PF01375.17 EJP66767.1 - 5.4e-05 22.9 0.2 0.00019 21.1 0.2 1.8 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain Tyrosinase PF00264.20 EJP66768.1 - 4.2e-44 151.5 2.7 4.2e-44 151.5 2.7 3.3 2 1 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EJP66768.1 - 0.0047 17.6 0.0 0.0047 17.6 0.0 3.1 2 1 1 3 3 3 1 Tyosinase C-terminal domain FAD_binding_4 PF01565.23 EJP66769.1 - 1e-25 90.1 0.8 1.9e-25 89.2 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain Asp PF00026.23 EJP66770.1 - 2.6e-59 201.2 0.0 3.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP66770.1 - 7.4e-08 32.8 0.0 0.00013 22.3 0.0 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EJP66770.1 - 0.0065 16.3 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal DUF4141 PF13605.6 EJP66770.1 - 0.018 14.3 0.6 0.11 11.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) Asp_protease_2 PF13650.6 EJP66770.1 - 0.036 14.7 0.1 22 5.8 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease MFS_1 PF07690.16 EJP66771.1 - 7.7e-25 87.5 27.2 7.7e-25 87.5 27.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EJP66771.1 - 5.5e-07 29.2 13.7 0.00011 21.6 5.9 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB FAD_binding_3 PF01494.19 EJP66772.1 - 2.6e-07 30.2 2.2 0.00021 20.7 0.9 2.4 2 1 0 2 2 2 2 FAD binding domain DUF4430 PF14478.6 EJP66773.1 - 0.073 13.7 0.3 0.4 11.3 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4430) Varsurf_PPLC PF03490.13 EJP66773.1 - 0.13 12.2 0.0 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C ATP_transf PF09830.9 EJP66774.1 - 1.3e-17 63.7 0.0 2.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase Choline_transpo PF04515.12 EJP66775.1 - 6.6e-83 278.6 19.1 6.6e-83 278.6 19.1 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Rax2 PF12768.7 EJP66775.1 - 0.18 11.3 0.5 0.44 10.0 0.5 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Pex14_N PF04695.13 EJP66775.1 - 5.2 7.7 14.0 0.25 12.0 7.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sybindin PF04099.12 EJP66776.1 - 5.2e-23 81.6 0.0 6.3e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Pkinase PF00069.25 EJP66777.1 - 7.3e-56 189.5 0.0 1.4e-50 172.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66777.1 - 2.4e-36 125.4 0.0 3.4e-35 121.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP66777.1 - 3.8e-05 23.2 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EJP66777.1 - 0.0025 16.6 0.0 0.011 14.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EJP66777.1 - 0.013 15.5 0.1 0.043 13.7 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EJP66778.1 - 3.5e-49 167.5 0.0 4.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66778.1 - 1.7e-26 93.1 0.0 2.2e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP66778.1 - 0.00052 19.4 0.0 0.00083 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJP66778.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP66778.1 - 0.069 13.1 0.1 0.83 9.5 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 EJP66778.1 - 0.084 12.5 0.0 1.4 8.4 0.0 2.4 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 RNA_pol_L_2 PF13656.6 EJP66780.1 - 5.3e-30 103.0 0.0 7.2e-30 102.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EJP66780.1 - 7e-13 47.8 0.0 9.5e-13 47.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 EJP66781.1 - 2.6e-06 28.1 0.1 3.5e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EJP66781.1 - 7e-05 22.8 0.1 0.00014 21.8 0.1 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) G10 PF01125.17 EJP66782.1 - 2.7e-62 208.9 3.9 2.9e-62 208.7 3.9 1.0 1 0 0 1 1 1 1 G10 protein DUF1040 PF06288.13 EJP66782.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) zf-C2H2 PF00096.26 EJP66783.1 - 0.099 13.1 0.8 0.099 13.1 0.8 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP66783.1 - 0.13 13.2 0.7 0.13 13.2 0.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP66783.1 - 0.14 12.5 1.6 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EST1_DNA_bind PF10373.9 EJP66784.1 - 7.6e-47 160.1 2.0 7.6e-47 160.1 2.0 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EJP66784.1 - 3.2e-24 86.1 0.3 3.2e-24 86.1 0.3 2.6 3 0 0 3 3 3 1 Telomerase activating protein Est1 PfkB PF00294.24 EJP66785.1 - 2.9e-67 227.1 0.0 3.2e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_L2_C PF03947.18 EJP66786.1 - 2e-41 141.1 5.0 3.7e-41 140.3 5.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EJP66786.1 - 4.2e-13 49.1 0.3 1.2e-12 47.6 0.3 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.6 EJP66787.1 - 2.1e-05 23.9 0.0 4.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1770 PF08589.10 EJP66788.1 - 2.2e-34 118.3 0.7 2.9e-34 118.0 0.7 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) eRF1_2 PF03464.15 EJP66789.1 - 3e-45 153.8 0.0 4.9e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EJP66789.1 - 1.3e-39 135.2 0.5 2.8e-39 134.1 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EJP66789.1 - 2.2e-21 76.2 0.0 3.6e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EJP66789.1 - 4e-10 40.1 0.0 8.6e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EJP66789.1 - 6.9e-09 36.1 0.0 1.2e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF1093 PF06486.11 EJP66789.1 - 0.064 13.9 0.2 1.8 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1093) VASt PF16016.5 EJP66790.1 - 4.5e-33 114.8 0.5 1.3e-32 113.4 0.3 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EJP66790.1 - 3.2e-15 56.5 0.0 6e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EJP66790.1 - 5e-06 27.0 0.1 1.7e-05 25.3 0.1 2.0 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 EJP66790.1 - 0.002 18.0 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain BAR PF03114.18 EJP66790.1 - 0.0035 17.0 0.0 0.019 14.6 0.0 2.1 2 0 0 2 2 2 1 BAR domain Asp PF00026.23 EJP66791.1 - 2e-29 103.0 1.8 1.6e-28 100.1 1.8 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EJP66791.1 - 0.049 14.3 0.5 4.5 8.0 0.1 2.5 2 1 0 2 2 2 0 Aspartyl protease DUF4360 PF14273.6 EJP66792.1 - 2.5e-09 37.3 0.1 4.3e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Zn_clus PF00172.18 EJP66793.1 - 1.3e-06 28.5 11.0 2.4e-06 27.5 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAGidase PF07555.13 EJP66794.1 - 1.4e-103 346.3 0.2 2.2e-103 345.6 0.2 1.3 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.15 EJP66794.1 - 6.6e-16 59.2 3.2 3.3e-14 53.7 3.2 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.14 EJP66794.1 - 0.00011 22.4 0.4 0.00024 21.4 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus ADH_zinc_N PF00107.26 EJP66796.1 - 1.1e-27 96.6 0.8 2.4e-27 95.5 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP66796.1 - 2.6e-20 73.8 0.1 7.4e-20 72.4 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP66796.1 - 3.9e-09 36.4 0.0 1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EJP66796.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 EJP66797.1 - 1.9e-43 148.2 3.1 3.8e-43 147.2 3.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP66797.1 - 8.2e-40 136.8 4.1 1.4e-38 132.8 4.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP66797.1 - 5.5e-07 29.7 0.7 5.5e-07 29.7 0.7 2.1 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EJP66797.1 - 0.0024 17.8 0.3 0.0049 16.8 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 EJP66797.1 - 0.0072 16.4 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EJP66797.1 - 0.0092 15.5 0.3 0.044 13.2 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 EJP66797.1 - 0.019 15.5 0.8 0.032 14.8 0.3 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.10 EJP66797.1 - 0.021 14.2 0.1 0.049 13.0 0.1 1.6 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 EJP66797.1 - 0.063 12.6 0.0 0.68 9.2 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_3 PF01494.19 EJP66797.1 - 0.065 12.5 0.7 0.083 12.1 0.7 1.4 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EJP66797.1 - 0.2 10.3 2.9 0.72 8.5 1.3 2.0 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 EJP66797.1 - 0.31 10.9 3.7 0.85 9.5 2.4 2.5 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3074 PF11274.8 EJP66798.1 - 4.5e-59 199.5 0.4 6.9e-56 189.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) UBN_AB PF14075.6 EJP66798.1 - 0.2 11.3 13.6 0.4 10.4 13.6 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Mu-like_Pro PF10123.9 EJP66798.1 - 0.23 11.0 12.5 0.68 9.4 12.5 1.8 1 0 0 1 1 1 0 Mu-like prophage I protein Mucin PF01456.17 EJP66798.1 - 3.9 7.5 12.1 16 5.5 6.3 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein MRP-S26 PF14943.6 EJP66798.1 - 5 7.0 19.7 13 5.7 19.7 1.7 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2428 PF10350.9 EJP66799.1 - 3.8e-61 206.8 0.8 7.3e-61 205.8 0.8 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EJP66799.1 - 1.6e-05 24.8 8.7 0.55 10.6 0.1 7.1 7 0 0 7 7 7 2 HEAT repeat Ribosomal_L1 PF00687.21 EJP66800.1 - 4.5e-45 153.9 0.2 5.3e-45 153.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Glyco_transf_22 PF03901.17 EJP66801.1 - 2.9e-59 201.4 21.2 3.6e-59 201.1 21.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family APT PF03440.14 EJP66801.1 - 0.061 13.3 0.6 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain Skp1 PF01466.19 EJP66802.1 - 1.1e-29 102.3 0.4 3.5e-29 100.7 0.4 1.9 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EJP66802.1 - 8.1e-22 77.2 0.1 2.1e-21 75.9 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Ribosomal_L39 PF00832.20 EJP66803.1 - 4.4e-21 74.2 10.8 6.1e-21 73.8 10.8 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein Arf PF00025.21 EJP66804.1 - 4.1e-59 199.0 0.2 5.4e-57 192.1 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EJP66804.1 - 8.1e-10 39.0 0.1 1.3e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EJP66804.1 - 3.2e-08 33.1 0.1 7.2e-08 32.0 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 EJP66804.1 - 2.1e-07 30.7 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EJP66804.1 - 3.2e-06 26.7 0.0 4.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EJP66804.1 - 3.1e-05 23.5 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EJP66804.1 - 0.0096 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GMC_oxred_N PF00732.19 EJP66807.1 - 1e-45 156.4 0.5 1.4e-45 155.9 0.5 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP66807.1 - 1.9e-25 90.1 0.8 1.2e-24 87.5 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EJP66807.1 - 3e-07 29.9 0.7 4.6e-05 22.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EJP66807.1 - 1.4e-05 24.5 0.1 0.00018 20.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP66807.1 - 0.00042 19.7 0.0 0.00077 18.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJP66807.1 - 0.00053 19.7 0.8 0.21 11.2 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP66807.1 - 0.00076 19.7 0.2 0.0018 18.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EJP66807.1 - 0.018 13.8 0.2 0.027 13.2 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EJP66807.1 - 0.051 12.8 0.4 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 Thi4 family PDEase_I PF00233.19 EJP66808.1 - 2.5e-64 217.3 0.0 4.1e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF370 PF04025.12 EJP66808.1 - 0.2 11.8 0.0 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF370) UCH PF00443.29 EJP66809.1 - 4.8e-68 229.4 0.0 8e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EJP66809.1 - 7e-13 49.0 0.0 1.8e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EJP66809.1 - 1.6e-11 44.4 0.0 0.00013 21.7 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Nop14 PF04147.12 EJP66809.1 - 0.37 8.9 11.6 0.73 8.0 11.6 1.4 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 EJP66809.1 - 2.1 8.1 7.8 3.1 7.6 6.6 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EJP66809.1 - 3.1 6.0 12.4 5.5 5.2 12.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M16_M PF16187.5 EJP66810.1 - 4.3e-95 318.2 0.6 7e-95 317.5 0.6 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EJP66810.1 - 1.7e-35 122.2 0.1 6.8e-35 120.2 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EJP66810.1 - 3.9e-30 105.2 0.0 1.2e-17 64.6 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF3140 PF11338.8 EJP66811.1 - 1.9e-33 114.8 2.3 1.9e-33 114.8 2.3 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3140) Hva1_TUDOR PF11160.8 EJP66811.1 - 1.4e-11 44.3 1.4 1.4e-11 44.3 1.4 3.7 3 1 1 4 4 4 1 Hypervirulence associated proteins TUDOR domain DUF4551 PF15087.6 EJP66811.1 - 0.69 8.7 17.6 0.84 8.4 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NUDIX_2 PF13869.6 EJP66814.1 - 7e-78 260.5 0.0 8.2e-78 260.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase zf-CHCC PF10276.9 EJP66815.1 - 1.1e-13 51.0 0.8 1.6e-13 50.5 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-C2H2_4 PF13894.6 EJP66815.1 - 0.11 13.4 0.8 0.28 12.1 0.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Prok-RING_1 PF14446.6 EJP66815.1 - 0.25 11.3 2.1 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-CCHC PF00098.23 EJP66816.1 - 7.7e-06 25.7 3.4 1.2e-05 25.2 3.4 1.3 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 EJP66816.1 - 0.0027 16.1 8.5 0.003 15.9 8.5 1.1 1 0 0 1 1 1 1 CDC45-like protein SRP-alpha_N PF04086.13 EJP66816.1 - 2.3 8.1 15.3 3.2 7.6 15.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.9 EJP66816.1 - 3.1 6.5 10.0 3.6 6.3 10.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 EJP66816.1 - 3.8 6.2 8.8 3.8 6.2 8.8 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EJP66816.1 - 7.4 6.6 6.1 8.6 6.3 6.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pet100 PF09803.9 EJP66817.1 - 2.2e-17 63.3 0.6 2.6e-17 63.1 0.6 1.1 1 0 0 1 1 1 1 Pet100 Transcrip_reg PF01709.20 EJP66818.1 - 2.1e-51 174.7 0.0 2.3e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator HEAT_2 PF13646.6 EJP66819.1 - 3.9e-10 40.0 5.7 0.17 12.3 0.0 7.0 7 0 0 7 7 7 3 HEAT repeats HEAT PF02985.22 EJP66819.1 - 5e-07 29.4 8.3 1.5 9.3 0.0 8.3 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EJP66819.1 - 1.9e-06 28.4 0.2 0.14 12.8 0.0 5.2 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 EJP66819.1 - 7.2e-05 22.1 1.2 0.081 12.1 0.0 4.8 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain UNC45-central PF11701.8 EJP66819.1 - 0.00019 21.4 3.8 0.17 11.8 0.0 5.6 5 1 0 5 5 5 1 Myosin-binding striated muscle assembly central Adaptin_N PF01602.20 EJP66819.1 - 0.0002 20.1 4.5 1.2 7.6 0.0 5.3 5 0 0 5 5 5 3 Adaptin N terminal region HEAT_EZ PF13513.6 EJP66819.1 - 0.003 18.0 6.1 2.1 8.9 0.0 6.7 6 0 0 6 6 6 1 HEAT-like repeat IFRD PF05004.13 EJP66819.1 - 0.8 8.7 21.0 1.3 8.1 0.4 6.1 6 2 0 6 6 6 0 Interferon-related developmental regulator (IFRD) WD40 PF00400.32 EJP66820.1 - 1.4 9.9 6.1 79 4.4 0.0 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat Peroxin-3 PF04882.12 EJP66821.1 - 4.8e-170 566.6 0.1 4.8e-170 566.6 0.1 1.3 2 0 0 2 2 2 1 Peroxin-3 ATG101 PF07855.12 EJP66822.1 - 1.6e-53 180.9 0.4 2.1e-53 180.5 0.4 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 Striatin PF08232.12 EJP66822.1 - 0.088 13.4 0.9 0.13 12.9 0.9 1.2 1 0 0 1 1 1 0 Striatin family Forkhead PF00250.18 EJP66823.1 - 2.4e-34 117.5 0.0 4.8e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain EF-hand_4 PF12763.7 EJP66824.1 - 4.6e-24 84.4 0.0 1.6e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 EJP66824.1 - 1.1e-06 28.3 0.5 9.3e-05 22.1 0.1 2.8 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.11 EJP66824.1 - 0.00055 20.3 82.5 0.00077 19.8 19.4 7.9 7 2 2 9 9 9 3 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 EJP66824.1 - 0.031 14.7 0.0 1.3 9.5 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair E3_binding PF02817.17 EJP66824.1 - 0.045 14.1 0.0 0.23 11.8 0.2 2.1 2 0 0 2 2 2 0 e3 binding domain LOH1CR12 PF10158.9 EJP66824.1 - 7.4 6.6 8.1 16 5.6 8.1 1.5 1 0 0 1 1 1 0 Tumour suppressor protein PH PF00169.29 EJP66825.1 - 0.027 15.0 0.0 0.067 13.7 0.0 1.7 1 0 0 1 1 1 0 PH domain VirDNA-topo-I_N PF09266.10 EJP66825.1 - 0.059 13.5 0.2 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal HupH_C PF04809.13 EJP66825.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region LRR_6 PF13516.6 EJP66825.1 - 3.2 8.0 6.1 91 3.5 0.1 5.1 6 0 0 6 6 6 0 Leucine Rich repeat Amino_oxidase PF01593.24 EJP66826.1 - 2.6e-52 178.6 0.0 3.6e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP66826.1 - 2.5e-11 43.6 0.5 1.3e-10 41.4 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP66826.1 - 5e-10 39.5 1.0 3.3e-09 36.8 1.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EJP66826.1 - 1.5e-08 34.4 0.0 3.2e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP66826.1 - 2.1e-07 30.4 0.2 8e-07 28.5 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EJP66826.1 - 1.1e-06 28.1 0.1 0.00044 19.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EJP66826.1 - 2.4e-06 27.0 0.0 0.00022 20.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP66826.1 - 4.2e-06 26.1 0.0 0.00017 20.8 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EJP66826.1 - 7.1e-06 25.0 0.1 3.7e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EJP66826.1 - 1.9e-05 24.1 0.0 3.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EJP66826.1 - 0.0037 16.4 0.1 0.0068 15.5 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EJP66826.1 - 0.014 16.0 0.1 0.034 14.7 0.1 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP66826.1 - 0.015 14.6 0.0 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP66826.1 - 0.043 13.8 0.4 12 5.9 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Aldedh PF00171.22 EJP66827.1 - 5.2e-166 552.7 1.6 5.9e-166 552.6 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EJP66827.1 - 0.0085 15.2 0.0 0.068 12.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) EutQ PF06249.12 EJP66828.1 - 1.4e-06 28.1 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EJP66828.1 - 1.7e-05 24.4 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EJP66828.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 EJP66828.1 - 0.048 13.4 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Cupin Pirin PF02678.16 EJP66828.1 - 0.075 13.0 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Pirin FAD_binding_3 PF01494.19 EJP66829.1 - 4.4e-17 62.4 2.5 1.5e-05 24.4 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 EJP66829.1 - 9.9e-09 35.2 1.1 0.00053 19.7 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP66829.1 - 3.1e-08 33.2 0.4 3.6e-05 23.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP66829.1 - 3.5e-07 29.6 0.1 5.9e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EJP66829.1 - 6.2e-06 26.4 0.1 1.5e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EJP66829.1 - 5.3e-05 22.8 0.1 0.00011 21.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP66829.1 - 0.00011 22.7 0.3 0.00049 20.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP66829.1 - 0.00024 20.3 0.1 0.0098 15.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EJP66829.1 - 0.00076 18.3 0.1 0.0021 16.9 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EJP66829.1 - 0.0032 16.6 0.4 0.037 13.1 0.4 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EJP66829.1 - 0.0074 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EJP66829.1 - 0.0076 15.5 0.2 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP66829.1 - 0.0093 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EJP66829.1 - 0.013 14.4 0.4 2 7.2 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NmrA PF05368.13 EJP66830.1 - 1.4e-17 64.0 0.0 2.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP66830.1 - 1.9e-10 40.9 0.0 5e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EJP66830.1 - 1.1e-05 25.1 0.1 7.3e-05 22.3 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EJP66830.1 - 0.00018 21.5 0.0 0.0006 19.8 0.1 1.9 2 0 0 2 2 2 1 KR domain DapB_N PF01113.20 EJP66830.1 - 0.03 14.4 0.2 0.59 10.3 0.2 2.4 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF5022 PF16425.5 EJP66830.1 - 0.037 13.5 0.1 0.088 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5022) Fungal_trans_2 PF11951.8 EJP66831.1 - 4.2e-51 174.0 2.2 6.6e-51 173.3 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP66831.1 - 2.4e-05 24.4 2.2 6.5e-05 23.0 2.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 EJP66832.1 - 5.9e-44 150.6 51.0 7.3e-44 150.3 51.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP66832.1 - 3.3e-07 29.3 43.0 4.9e-07 28.7 43.0 1.2 1 0 0 1 1 1 1 Amino acid permease PDR_CDR PF06422.12 EJP66832.1 - 0.082 12.8 1.5 0.46 10.4 1.2 2.5 1 1 0 1 1 1 0 CDR ABC transporter FAD_binding_6 PF00970.24 EJP66833.1 - 1.1e-29 102.7 0.0 1.7e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EJP66833.1 - 9.8e-27 93.8 0.0 1.5e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EJP66833.1 - 0.0002 21.5 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain TPR_1 PF00515.28 EJP66834.1 - 9.9e-29 98.0 19.8 3.7e-05 23.4 0.1 12.1 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 EJP66834.1 - 2.1e-24 83.6 32.1 0.0022 18.0 0.0 12.9 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_8 PF13181.6 EJP66834.1 - 4e-22 76.5 13.9 0.00091 19.3 0.1 11.7 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EJP66834.1 - 3.4e-15 56.1 18.2 0.00096 19.4 0.5 9.8 6 3 3 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 EJP66834.1 - 1.1e-14 53.3 12.9 0.013 15.5 0.1 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EJP66834.1 - 1.9e-14 53.9 19.6 0.0015 19.0 0.2 8.8 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 EJP66834.1 - 2.3e-14 52.8 19.5 0.2 12.6 0.1 12.2 12 2 2 14 14 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 EJP66834.1 - 1.9e-13 50.1 18.8 0.0067 17.0 0.0 11.1 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJP66834.1 - 1.2e-09 37.8 7.1 0.72 10.4 0.2 9.6 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP66834.1 - 1.2e-09 38.6 22.0 0.031 14.9 0.0 8.4 10 1 0 10 10 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 EJP66834.1 - 8.1e-09 35.1 3.8 2.8 7.9 0.1 8.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJP66834.1 - 0.00011 21.9 29.4 0.53 10.0 0.0 9.2 10 0 0 10 10 10 3 TPR repeat TPR_9 PF13371.6 EJP66834.1 - 0.0002 21.5 0.5 2.3 8.5 0.0 5.3 5 1 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP66834.1 - 0.035 14.3 16.3 0.14 12.4 1.0 6.4 7 0 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EJP66834.1 - 0.99 9.5 3.4 17 5.5 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PX PF00787.24 EJP66835.1 - 3.4e-20 72.1 0.0 3e-19 69.0 0.0 2.4 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EJP66835.1 - 3.2e-11 43.2 7.6 2.5e-07 30.5 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like mRNA_cap_enzyme PF01331.19 EJP66836.1 - 2.8e-54 183.9 0.0 4.2e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EJP66836.1 - 1.5e-34 118.9 0.0 2.3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EJP66836.1 - 3.3e-07 30.2 0.0 0.00023 20.9 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EJP66836.1 - 0.00043 20.6 0.0 0.00066 20.0 0.0 1.3 1 0 0 1 1 1 1 RNA ligase DUF4420 PF14390.6 EJP66836.1 - 0.069 12.4 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Putative PD-(D/E)XK family member, (DUF4420) HEAT_2 PF13646.6 EJP66838.1 - 0.00054 20.3 2.5 0.67 10.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EJP66838.1 - 0.0024 18.0 0.1 2.1 8.8 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Nitr_red_assoc PF09655.10 EJP66838.1 - 0.54 10.9 6.6 2.3 8.9 0.0 3.6 4 0 0 4 4 4 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) HEAT_EZ PF13513.6 EJP66838.1 - 0.54 10.8 5.1 2.4 8.7 0.0 4.5 5 0 0 5 5 5 0 HEAT-like repeat SNF5 PF04855.12 EJP66839.1 - 3.9e-64 216.7 0.9 9.5e-63 212.2 0.2 2.8 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Rz1 PF06085.11 EJP66839.1 - 1.4 8.7 5.6 3.9 7.3 5.6 1.8 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor Peptidase_M24 PF00557.24 EJP66840.1 - 1.1e-06 28.6 0.0 1.4e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 EJP66841.1 - 4.8e-15 55.2 18.4 6.1e-09 35.6 9.2 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 EJP66841.1 - 1.1e-05 25.2 8.1 0.0061 16.4 0.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EJP66841.1 - 0.00051 20.3 11.5 0.014 15.7 0.7 2.6 2 0 0 2 2 2 2 C1 domain zf-HC5HC2H PF13771.6 EJP66841.1 - 0.0015 18.8 3.2 0.16 12.2 0.6 2.4 2 0 0 2 2 2 2 PHD-like zinc-binding domain TraG-D_C PF12696.7 EJP66841.1 - 0.088 12.8 0.0 0.088 12.8 0.0 3.1 3 0 0 3 3 3 0 TraM recognition site of TraD and TraG Rubredoxin PF00301.20 EJP66841.1 - 0.16 12.0 2.9 0.24 11.4 0.2 2.7 2 0 0 2 2 2 0 Rubredoxin zf-PHD-like PF15446.6 EJP66841.1 - 0.35 10.5 6.5 2.4 7.7 1.9 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 EJP66841.1 - 1.4 8.6 13.6 0.028 13.9 3.6 2.9 3 0 0 3 3 3 0 PHD-finger Zf_RING PF16744.5 EJP66841.1 - 1.5 9.0 12.2 1.3 9.2 0.8 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 EJP66841.1 - 2.1 8.5 17.6 4.8 7.3 1.9 2.7 2 0 0 2 2 2 0 PHD-finger PUF PF00806.19 EJP66842.1 - 3.7e-27 92.5 0.0 0.00015 21.3 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EJP66842.1 - 1.5e-13 50.4 0.0 2.8e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 EJP66843.1 - 4.1e-67 226.3 1.6 4.1e-67 226.3 1.6 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66843.1 - 3e-53 180.7 0.1 3e-53 180.7 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EJP66843.1 - 2e-23 82.5 0.3 1.4e-22 79.8 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 EJP66843.1 - 2e-06 27.3 0.0 2e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EJP66843.1 - 4.8e-06 25.6 0.8 1.7e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase PH_11 PF15413.6 EJP66843.1 - 1.9e-05 25.1 0.6 1.9e-05 25.1 0.6 2.6 3 1 0 3 3 2 1 Pleckstrin homology domain PH PF00169.29 EJP66843.1 - 0.0014 19.1 0.2 0.0032 17.9 0.2 1.6 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 EJP66843.1 - 0.0015 17.5 0.8 0.0015 17.5 0.8 1.7 2 1 0 2 2 2 1 Haspin like kinase domain AAA_23 PF13476.6 EJP66843.1 - 0.0086 16.6 0.3 0.019 15.5 0.3 1.6 1 0 0 1 1 1 1 AAA domain Kdo PF06293.14 EJP66843.1 - 0.011 15.1 0.2 0.011 15.1 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family KIND PF16474.5 EJP66843.1 - 0.021 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain APH PF01636.23 EJP66843.1 - 0.025 14.5 0.5 0.025 14.5 0.5 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EJP66843.1 - 0.069 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HGTP_anticodon PF03129.20 EJP66844.1 - 1.6e-21 76.2 0.0 5.8e-21 74.4 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EJP66844.1 - 7.2e-08 32.6 0.0 8.6e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) UPF0113 PF03657.13 EJP66845.1 - 1.4e-26 92.6 0.0 2.2e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 EJP66845.1 - 3.4e-25 88.4 0.0 4.6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 EJP66845.1 - 0.038 13.9 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 PUA domain AA_kinase PF00696.28 EJP66846.1 - 1.7e-38 132.6 1.5 2.2e-38 132.2 1.5 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EJP66846.1 - 1e-17 63.9 0.8 1.8e-16 59.8 0.1 2.7 3 0 0 3 3 3 1 PUA domain Peptidase_M76 PF09768.9 EJP66847.1 - 3.1e-67 225.6 0.6 3.8e-67 225.3 0.6 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EJP66847.1 - 0.015 15.1 1.5 0.025 14.5 0.8 1.7 1 1 0 1 1 1 0 SprT-like family Peptidase_M91 PF14891.6 EJP66847.1 - 0.054 13.8 0.0 0.08 13.3 0.0 1.3 1 0 0 1 1 1 0 Effector protein PRIMA1 PF16101.5 EJP66847.1 - 0.14 12.2 0.9 0.25 11.4 0.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EP400_N PF15790.5 EJP66847.1 - 0.22 10.3 1.5 0.29 9.9 1.5 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Pkinase PF00069.25 EJP66848.1 - 3.8e-64 216.6 0.0 5.6e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66848.1 - 2.2e-39 135.3 0.0 3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP66848.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJP66848.1 - 0.0021 17.5 0.1 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EJP66848.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EJP66848.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 EJP66848.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 EJP66848.1 - 0.23 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EJP66848.1 - 0.26 10.0 0.7 0.35 9.6 0.7 1.3 1 1 0 1 1 1 0 Fungal protein kinase Dscam_C PF12355.8 EJP66848.1 - 0.34 11.9 2.8 0.64 11.0 2.8 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal TIP41 PF04176.13 EJP66850.1 - 3.8e-67 225.1 0.3 4.8e-67 224.8 0.3 1.1 1 0 0 1 1 1 1 TIP41-like family Efg1 PF10153.9 EJP66851.1 - 2.3e-34 118.2 8.4 2.3e-34 118.2 8.4 2.1 3 1 0 3 3 3 1 rRNA-processing protein Efg1 zinc_ribbon_16 PF17034.5 EJP66852.1 - 6.3e-17 62.0 5.9 1.9e-16 60.4 5.9 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EJP66852.1 - 4.4e-06 26.2 4.8 4.4e-06 26.2 4.8 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-FPG_IleRS PF06827.14 EJP66852.1 - 0.15 12.0 7.5 0.17 11.8 0.2 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS CAP_N PF01213.19 EJP66852.1 - 0.35 10.3 1.9 0.6 9.5 1.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RCDG1 PF15725.5 EJP66852.1 - 3.4 8.1 5.4 4.4 7.8 3.1 2.3 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Pkinase PF00069.25 EJP66853.1 - 6.7e-58 196.1 0.0 1.1e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66853.1 - 2e-20 73.2 0.0 3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJP66853.1 - 0.00014 21.0 0.0 0.00014 21.0 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EJP66853.1 - 0.00075 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJP66853.1 - 0.0024 17.8 0.2 0.013 15.5 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 EJP66853.1 - 0.013 15.2 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EJP66853.1 - 0.052 12.3 3.1 0.14 10.9 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Selenoprotein_S PF06936.11 EJP66853.1 - 0.49 10.2 2.4 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 Selenoprotein S (SelS) Codanin-1_C PF15296.6 EJP66853.1 - 3.7 7.6 6.6 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Codanin-1 C-terminus HNF-1_N PF04814.13 EJP66853.1 - 4 8.0 13.4 20 5.7 0.3 3.3 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus LRR_6 PF13516.6 EJP66854.1 - 1.2e-10 40.5 11.9 0.086 12.9 0.0 7.6 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.7 EJP66854.1 - 2.4e-10 40.1 0.1 2.2e-09 37.0 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EJP66854.1 - 2.6e-09 36.7 0.1 2.7e-07 30.3 0.0 3.0 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 EJP66854.1 - 1.7e-05 25.0 10.8 0.26 11.8 0.0 6.4 5 3 1 6 6 6 3 Leucine Rich repeats (2 copies) DUF5308 PF17233.2 EJP66854.1 - 0.61 10.3 3.3 0.43 10.8 1.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5308) LRR_1 PF00560.33 EJP66854.1 - 1.3 9.9 18.1 17 6.5 0.0 7.4 10 0 0 10 10 10 0 Leucine Rich Repeat His_Phos_1 PF00300.22 EJP66855.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Cu_amine_oxid PF01179.20 EJP66857.1 - 1.9e-160 534.3 0.0 2.3e-160 534.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EJP66857.1 - 9.3e-07 29.0 0.0 4.8e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 EJP66857.1 - 3.2e-06 27.5 0.0 6.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Collagen PF01391.18 EJP66857.1 - 0.14 11.9 5.2 0.26 11.0 5.2 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Fungal_trans PF04082.18 EJP66858.1 - 1.8e-11 43.6 0.1 1.8e-11 43.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Spt20 PF12090.8 EJP66858.1 - 3.7e-06 26.7 18.1 7.3e-06 25.8 18.1 1.4 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 EJP66858.1 - 0.00028 20.0 11.5 0.00056 19.0 11.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Zn_clus PF00172.18 EJP66858.1 - 0.0013 18.8 6.8 0.0024 18.0 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2148 PF09918.9 EJP66858.1 - 0.0036 17.3 0.4 0.68 10.0 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized protein containing a ferredoxin domain (DUF2148) Suf PF05843.14 EJP66858.1 - 0.029 14.4 12.1 0.85 9.5 5.5 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) V_ATPase_I PF01496.19 EJP66858.1 - 0.24 9.3 0.4 0.44 8.4 0.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SARAF PF06682.12 EJP66858.1 - 0.25 11.0 10.8 0.4 10.3 10.8 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SPX PF03105.19 EJP66858.1 - 0.46 10.4 9.5 0.95 9.3 4.6 2.2 2 0 0 2 2 2 0 SPX domain DUF4175 PF13779.6 EJP66858.1 - 0.93 7.3 13.2 1.5 6.6 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.10 EJP66858.1 - 1.1 7.9 29.2 0.16 10.6 24.9 1.7 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 EJP66858.1 - 1.6 7.4 6.9 2.6 6.7 6.9 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 EJP66858.1 - 1.6 9.7 13.1 0.5 11.3 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Apc15p PF05841.11 EJP66858.1 - 5.6 7.8 18.5 12 6.7 3.8 2.4 2 0 0 2 2 2 0 Apc15p protein p450 PF00067.22 EJP66859.1 - 1.7e-66 224.9 0.0 2.2e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lustrin_cystein PF14625.6 EJP66859.1 - 0.67 10.4 3.1 0.46 10.9 0.7 1.9 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Iwr1 PF08574.10 EJP66860.1 - 7.7e-17 62.1 9.2 7.7e-17 62.1 9.2 3.7 3 1 1 4 4 4 1 Transcription factor Iwr1 Spt20 PF12090.8 EJP66860.1 - 1.4 8.5 11.7 3.1 7.4 11.7 1.5 1 0 0 1 1 1 0 Spt20 family AMPK1_CBM PF16561.5 EJP66861.1 - 4.3e-07 30.1 0.0 6.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DEAD PF00270.29 EJP66862.1 - 1.2e-28 100.0 0.0 2.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP66862.1 - 4.3e-20 72.1 0.0 7.8e-18 64.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP66862.1 - 0.00055 20.0 0.0 0.0019 18.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EJP66862.1 - 0.026 13.3 0.3 0.94 8.2 0.0 2.2 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 EJP66862.1 - 0.068 13.4 0.1 12 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain FAM176 PF14851.6 EJP66863.1 - 0.0087 15.7 5.5 0.0087 15.7 5.5 4.2 3 1 1 4 4 4 2 FAM176 family TFIIA PF03153.13 EJP66864.1 - 0.36 10.8 13.7 0.5 10.3 13.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arylesterase PF01731.20 EJP66866.1 - 0.0015 18.7 0.0 0.0041 17.3 0.0 1.8 2 0 0 2 2 2 1 Arylesterase Pyr_redox_2 PF07992.14 EJP66867.1 - 4.1e-15 55.8 0.0 3.2e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP66867.1 - 4.5e-12 46.0 0.1 8.9e-11 41.9 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EJP66867.1 - 5.4e-11 41.6 0.4 3.2e-10 39.0 0.0 2.3 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP66867.1 - 6.8e-11 42.0 0.0 2.2e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP66867.1 - 2.7e-07 30.1 0.1 0.00027 20.2 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 EJP66867.1 - 1.3e-06 28.1 0.6 0.14 11.8 0.0 3.2 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EJP66867.1 - 1.9e-05 25.2 0.1 0.014 16.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP66867.1 - 2e-05 24.7 0.9 0.3 11.1 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 EJP66867.1 - 0.00013 21.7 0.0 0.0048 16.5 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EJP66867.1 - 0.00082 19.4 0.1 0.06 13.4 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EJP66867.1 - 0.002 17.4 0.1 0.15 11.3 0.1 2.4 3 0 0 3 3 3 1 Thi4 family F420_oxidored PF03807.17 EJP66867.1 - 0.0021 18.6 0.0 0.38 11.4 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 EJP66867.1 - 0.0044 17.4 0.0 0.57 10.6 0.0 3.0 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EJP66867.1 - 0.0075 15.4 0.3 0.018 14.1 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EJP66867.1 - 0.0092 15.1 0.1 0.48 9.4 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 EJP66867.1 - 0.017 14.5 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EJP66867.1 - 0.023 14.9 0.0 0.075 13.2 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EJP66867.1 - 0.03 13.9 0.0 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HI0933_like PF03486.14 EJP66867.1 - 0.033 12.9 0.3 0.34 9.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 EJP66867.1 - 0.058 13.6 0.1 2.4 8.4 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 EJP66867.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 EJP66867.1 - 0.16 11.3 0.4 5.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 EJP66867.1 - 0.18 11.7 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Ribosomal_S19e PF01090.19 EJP66868.1 - 1.1e-58 196.8 0.2 1.3e-58 196.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Zip PF02535.22 EJP66869.1 - 1.8e-60 205.0 0.1 2.1e-60 204.7 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MDM10 PF12519.8 EJP66870.1 - 3.6e-162 540.5 0.0 5.7e-162 539.8 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EJP66870.1 - 0.092 12.2 0.1 7.1 6.0 0.2 2.9 2 1 0 2 2 2 0 Eukaryotic porin HAD PF12710.7 EJP66871.1 - 2.4e-05 24.8 0.0 0.00012 22.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 EJP66872.1 - 1.3e-08 34.8 0.0 2.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP66872.1 - 2.6e-05 24.1 0.8 8.2e-05 22.5 0.3 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain LSM PF01423.22 EJP66873.1 - 2.8e-16 58.9 0.3 3.3e-16 58.7 0.3 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EJP66873.1 - 0.0006 19.4 0.1 0.00088 18.9 0.1 1.3 1 0 0 1 1 1 1 Hfq protein PhnA PF03831.14 EJP66873.1 - 0.11 12.3 0.0 0.95 9.4 0.0 2.1 2 0 0 2 2 2 0 PhnA domain LDB19 PF13002.7 EJP66874.1 - 1.8e-36 125.7 0.4 2.9e-36 125.0 0.4 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EJP66874.1 - 7.3e-06 26.1 0.0 2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LigB PF02900.18 EJP66875.1 - 3.7e-34 118.1 0.0 4.4e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PTS_2-RNA PF01885.16 EJP66876.1 - 1.1e-64 217.8 0.0 1.7e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF3818 PF12825.7 EJP66877.1 - 1e-49 169.4 0.4 1.7e-33 116.1 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EJP66877.1 - 1.7e-39 134.7 0.0 8.8e-39 132.5 0.0 2.1 2 0 0 2 2 2 1 PX-associated DUF4449 PF14613.6 EJP66878.1 - 3.9e-58 196.2 2.1 3.9e-58 196.2 2.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) UCH_1 PF13423.6 EJP66878.1 - 0.25 10.9 0.1 0.25 10.9 0.1 2.0 2 1 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_46 PF01374.18 EJP66878.1 - 3 7.4 8.4 0.32 10.6 1.7 2.5 3 0 0 3 3 3 0 Glycosyl hydrolase family 46 JAB PF01398.21 EJP66879.1 - 2.8e-31 107.9 0.1 4.4e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EJP66879.1 - 7.8e-19 68.4 0.1 1.3e-18 67.6 0.1 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EJP66879.1 - 4.9e-06 26.3 0.0 1.1e-05 25.2 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain GBP_repeat PF02526.14 EJP66879.1 - 0.082 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Glycophorin-binding protein UPF0172 PF03665.13 EJP66879.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Amidase PF01425.21 EJP66880.1 - 1.8e-51 175.6 0.0 1.5e-49 169.2 0.0 2.1 1 1 0 1 1 1 1 Amidase FAD_binding_3 PF01494.19 EJP66882.1 - 2.3e-13 50.1 0.0 9.2e-13 48.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJP66882.1 - 2.8e-06 27.2 0.2 2.8e-05 23.9 0.2 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EJP66882.1 - 9.4e-05 21.9 0.0 0.00029 20.3 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP66882.1 - 0.00053 20.2 2.8 0.00075 19.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EJP66882.1 - 0.0007 18.8 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EJP66882.1 - 0.00085 18.6 0.0 0.0031 16.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EJP66882.1 - 0.00091 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.14 EJP66882.1 - 0.0079 14.9 0.0 0.0079 14.9 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EJP66882.1 - 0.03 14.9 0.0 0.07 13.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EJP66882.1 - 0.046 13.0 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EJP66882.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 EJP66883.1 - 4.5e-37 127.8 54.4 9.2e-36 123.5 50.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 EJP66883.1 - 1.5e-05 23.9 2.7 1.5e-05 23.9 2.7 2.8 3 0 0 3 3 3 1 LacY proton/sugar symporter MFS_1_like PF12832.7 EJP66883.1 - 0.0082 15.0 30.1 0.013 14.4 18.8 2.8 1 1 2 3 3 3 3 MFS_1 like family CMAS PF02353.20 EJP66885.1 - 9.4e-61 205.5 0.1 2.1e-60 204.3 0.1 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EJP66885.1 - 3.7e-10 40.3 0.0 6.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP66885.1 - 6e-10 39.7 0.0 1.3e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP66885.1 - 1.1e-08 35.1 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP66885.1 - 0.0024 18.6 0.0 0.0045 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP66885.1 - 0.0041 16.9 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EJP66885.1 - 0.0078 16.0 0.0 0.032 14.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 EJP66885.1 - 0.05 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Colipase_C PF02740.14 EJP66885.1 - 0.12 12.5 0.3 0.29 11.3 0.3 1.5 1 0 0 1 1 1 0 Colipase, C-terminal domain MTS PF05175.14 EJP66885.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 EJP66886.1 - 4.8e-58 197.0 0.0 6.3e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 EJP66887.1 - 2.1e-10 40.8 0.1 1.9e-09 37.7 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain SMK-1 PF04802.15 EJP66887.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 Skp1_POZ PF03931.15 EJP66887.1 - 0.17 12.1 0.5 0.62 10.3 0.2 2.1 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain S1-P1_nuclease PF02265.16 EJP66888.1 - 8.7e-69 232.1 0.0 1e-68 231.9 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease MFS_1 PF07690.16 EJP66889.1 - 1.1e-41 142.9 27.5 1.1e-41 142.9 27.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP66889.1 - 3.7e-13 49.2 6.5 3.7e-13 49.2 6.5 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP66889.1 - 9.6e-08 30.9 1.7 1.8e-07 30.0 1.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EJP66889.1 - 0.1 10.8 6.8 3.3 5.9 3.6 2.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fzo_mitofusin PF04799.13 EJP66889.1 - 0.34 10.5 0.7 0.7 9.4 0.7 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF373 PF04123.13 EJP66889.1 - 2.1 7.7 13.5 1.3 8.4 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF373) CPP1-like PF11833.8 EJP66889.1 - 7.5 6.2 8.9 19 4.9 0.1 3.2 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Zn_clus PF00172.18 EJP66890.1 - 1e-07 32.0 12.1 1e-07 32.0 12.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP66890.1 - 1.3e-05 24.4 0.0 6.5e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zinc_ribbon_2 PF13240.6 EJP66890.1 - 2 8.2 4.7 3.7 7.4 0.4 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF3328 PF11807.8 EJP66891.1 - 2e-44 152.0 0.0 2.7e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Kringle PF00051.18 EJP66891.1 - 0.027 14.8 0.9 0.91 9.9 0.2 2.5 2 0 0 2 2 2 0 Kringle domain CDH-cyt PF16010.5 EJP66893.1 - 3.6e-11 43.1 0.4 9.8e-11 41.7 0.4 1.7 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EJP66893.1 - 1e-06 28.9 12.4 2.2e-06 27.8 12.4 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EJP66893.1 - 0.00029 21.1 0.0 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 DOMON domain DUF1516 PF07457.11 EJP66893.1 - 0.021 15.0 2.7 0.045 13.9 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) DUF2427 PF10348.9 EJP66893.1 - 0.053 13.3 6.1 0.48 10.3 4.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) DUF4079 PF13301.6 EJP66893.1 - 7.9 6.6 15.8 2.3 8.4 7.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) Pro-kuma_activ PF09286.11 EJP66894.1 - 4.5e-17 62.7 0.1 9.5e-15 55.1 0.0 2.9 2 1 1 3 3 3 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP66894.1 - 4.1e-09 36.1 0.3 6.4e-09 35.5 0.3 1.3 1 0 0 1 1 1 1 Subtilase family DUF3328 PF11807.8 EJP66895.1 - 3.1e-52 177.5 1.4 3.8e-52 177.2 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pro-kuma_activ PF09286.11 EJP66896.1 - 8.7e-33 113.6 0.0 4e-32 111.5 0.0 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP66896.1 - 0.00025 20.4 0.0 0.00037 19.8 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DUF3328 PF11807.8 EJP66897.1 - 2.6e-54 184.3 0.8 3.2e-54 184.0 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) OPT PF03169.15 EJP66898.1 - 5.5e-78 263.1 46.9 6.5e-78 262.9 46.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PetL PF05115.14 EJP66898.1 - 0.11 12.5 0.1 0.11 12.5 0.1 4.3 5 0 0 5 5 5 0 Cytochrome B6-F complex subunit VI (PetL) DNA_binding_1 PF01035.20 EJP66899.1 - 3e-26 91.3 0.5 5.5e-25 87.3 0.5 2.3 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Fmp27 PF10344.9 EJP66900.1 - 7.2e-200 666.3 0.0 1.8e-199 665.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 EJP66900.1 - 7.4e-195 648.3 1.6 7.4e-195 648.3 1.6 2.3 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EJP66900.1 - 1.4e-184 614.5 0.4 2.3e-184 613.8 0.4 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EJP66900.1 - 3.2e-56 189.8 0.0 7.5e-56 188.6 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EJP66900.1 - 3.8e-56 189.3 0.8 8.8e-56 188.1 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EJP66900.1 - 6.4e-32 110.3 0.0 6.4e-32 110.3 0.0 3.0 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain RRM_1 PF00076.22 EJP66902.1 - 3.1e-12 46.1 0.0 5.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hamartin PF04388.12 EJP66902.1 - 2 7.0 9.6 2.5 6.7 9.6 1.1 1 0 0 1 1 1 0 Hamartin protein p450 PF00067.22 EJP66903.1 - 2.8e-57 194.5 0.0 3.1e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MOR2-PAG1_N PF14222.6 EJP66905.1 - 1.7e-214 713.9 0.0 2.8e-214 713.2 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EJP66905.1 - 1.6e-89 300.1 0.0 8e-89 297.8 0.0 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EJP66905.1 - 1.4e-38 132.3 7.6 4e-15 54.6 0.1 3.3 1 1 2 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.7 EJP66905.1 - 0.017 15.1 1.5 1.1 9.3 0.1 3.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DIM1 PF02966.16 EJP66906.1 - 4.8e-70 233.5 0.1 5.4e-70 233.3 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EJP66906.1 - 0.00016 21.6 0.0 0.00021 21.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EJP66906.1 - 0.0083 16.4 0.9 0.013 15.8 0.8 1.4 1 1 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 EJP66906.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DUF2034 PF10356.9 EJP66907.1 - 8.1e-27 93.8 0.0 1.7e-12 47.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) GST_C PF00043.25 EJP66908.1 - 1.5e-13 50.8 0.1 2.3e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EJP66908.1 - 1.5e-13 50.8 0.0 3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EJP66908.1 - 8.5e-13 48.5 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EJP66908.1 - 4.9e-11 42.7 0.1 9.1e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EJP66908.1 - 2.4e-10 40.3 0.1 4.1e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EJP66908.1 - 2.3e-09 37.4 0.0 4.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EJP66908.1 - 0.0067 17.2 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 EJP66908.1 - 0.029 15.0 0.0 0.65 10.6 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF421 PF04239.12 EJP66908.1 - 0.096 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF421) GST_C_6 PF17171.4 EJP66908.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mito_fiss_reg PF05308.11 EJP66909.1 - 0.041 13.9 12.5 0.079 13.0 12.5 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator Apis_Csd PF11671.8 EJP66909.1 - 0.2 11.7 5.0 0.35 10.9 5.0 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein PRIMA1 PF16101.5 EJP66909.1 - 4.8 7.3 11.5 11 6.1 11.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Lon_C PF05362.13 EJP66910.1 - 1.2e-65 220.9 0.0 2.1e-65 220.1 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EJP66910.1 - 1.6e-32 113.1 0.2 3.8e-32 111.9 0.2 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EJP66910.1 - 5.3e-22 78.7 0.0 2.1e-21 76.7 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EJP66910.1 - 4.7e-07 29.7 0.0 1.4e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EJP66910.1 - 7e-07 29.3 0.0 1.7e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJP66910.1 - 1.6e-06 28.4 0.0 6.7e-06 26.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EJP66910.1 - 3.6e-05 24.1 0.0 0.00038 20.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 EJP66910.1 - 6.4e-05 22.0 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 EJP66910.1 - 9.5e-05 22.2 0.1 0.00076 19.3 0.0 2.6 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EJP66910.1 - 0.00073 20.0 1.6 0.0019 18.6 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EJP66910.1 - 0.013 16.0 0.4 0.08 13.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EJP66910.1 - 0.02 14.9 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EJP66910.1 - 0.02 14.6 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EJP66910.1 - 0.05 13.5 0.2 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase DNTTIP1_dimer PF18192.1 EJP66910.1 - 0.052 13.9 0.3 1.7 9.0 0.1 3.1 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain RNA_helicase PF00910.22 EJP66910.1 - 0.055 13.9 0.0 0.17 12.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 EJP66910.1 - 0.072 13.2 0.2 0.46 10.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_7 PF12775.7 EJP66910.1 - 0.077 12.5 0.5 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EJP66910.1 - 0.094 12.6 0.2 1.7 8.5 0.0 2.5 1 1 1 2 2 2 0 NTPase ClpB_D2-small PF10431.9 EJP66910.1 - 0.59 10.2 6.4 0.13 12.3 0.5 2.9 3 0 0 3 3 3 0 C-terminal, D2-small domain, of ClpB protein Pkinase PF00069.25 EJP66911.1 - 3.2e-12 46.4 0.1 4.2e-11 42.7 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66911.1 - 9.2e-10 38.2 0.0 8.9e-09 35.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 EJP66912.1 - 4.2e-21 75.3 11.9 4.2e-21 75.3 11.9 1.8 1 1 2 3 3 3 1 Major Facilitator Superfamily DUF202 PF02656.15 EJP66912.1 - 1 9.8 4.3 0.99 9.9 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Homeobox_KN PF05920.11 EJP66913.1 - 1.7e-16 59.8 0.3 1.7e-16 59.8 0.3 2.5 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EJP66913.1 - 1.7e-07 30.9 0.4 7.8e-07 28.9 0.1 2.3 2 0 0 2 2 2 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 EJP66913.1 - 3.7e-05 23.7 1.8 0.025 14.6 0.0 3.3 3 1 0 3 3 3 2 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 EJP66913.1 - 0.0023 18.6 1.1 0.0023 18.6 1.1 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP66913.1 - 0.0077 16.6 16.2 0.27 11.8 0.8 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type Elf1 PF05129.13 EJP66913.1 - 0.13 12.3 0.4 0.48 10.5 0.1 2.1 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_jaz PF12171.8 EJP66913.1 - 0.14 12.5 1.6 0.46 10.8 1.6 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EJP66913.1 - 3.8 7.9 8.4 73 3.8 0.0 4.2 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF868 PF05910.12 EJP66914.1 - 0.085 12.5 0.5 0.13 11.8 0.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) DUF2516 PF10724.9 EJP66916.1 - 0.67 10.3 4.7 2.3 8.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) Ank_2 PF12796.7 EJP66917.1 - 6.2e-73 241.4 14.9 3.4e-13 50.0 0.0 9.0 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP66917.1 - 8e-61 201.7 8.5 2.9e-09 37.3 0.2 11.5 5 3 7 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP66917.1 - 1.5e-56 181.7 11.9 0.00012 22.2 0.0 14.9 15 0 0 15 15 15 11 Ankyrin repeat Ank_5 PF13857.6 EJP66917.1 - 1.9e-49 165.1 16.5 9.5e-10 38.5 0.1 11.9 5 3 6 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 EJP66917.1 - 2.5e-47 157.3 22.0 1.2e-06 28.6 0.0 14.3 14 0 0 14 14 14 11 Ankyrin repeat GATase_7 PF13537.6 EJP66917.1 - 0.024 14.5 0.0 33 4.4 0.0 4.3 4 0 0 4 4 4 0 Glutamine amidotransferase domain Cys_rich_FGFR PF00839.17 EJP66917.1 - 0.94 9.7 4.3 7.4 6.8 0.1 3.5 4 0 0 4 4 4 0 Cysteine rich repeat Ank_2 PF12796.7 EJP66918.1 - 1.3e-53 179.6 26.3 7e-16 58.6 0.3 5.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP66918.1 - 7.2e-41 138.1 15.8 5e-09 36.5 0.0 8.8 2 1 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP66918.1 - 3.9e-35 115.9 6.8 0.00074 19.8 0.0 10.1 10 1 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 EJP66918.1 - 9.2e-31 104.9 26.4 2.7e-05 24.4 0.0 9.8 9 1 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EJP66918.1 - 1e-25 89.4 18.6 8.6e-09 35.5 0.2 5.9 4 2 2 6 6 6 4 Ankyrin repeats (many copies) DUF4988 PF16378.5 EJP66918.1 - 0.0056 16.4 0.0 1 9.0 0.0 3.6 2 1 1 3 3 3 1 Domain of unknown function DUF1843 PF08898.10 EJP66918.1 - 8.6 6.9 8.1 5.5 7.6 1.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) Ras PF00071.22 EJP66919.1 - 1.7e-65 219.5 0.5 2e-65 219.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP66919.1 - 6.9e-36 123.1 0.1 1.3e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP66919.1 - 3.2e-16 59.3 0.1 3.8e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EJP66919.1 - 2.2e-05 24.4 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EJP66919.1 - 2.4e-05 24.4 0.0 0.0001 22.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJP66919.1 - 8.7e-05 22.1 0.4 0.00023 20.8 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EJP66919.1 - 0.00026 20.4 0.1 0.00034 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EJP66919.1 - 0.00046 19.7 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EJP66919.1 - 0.00084 19.8 0.1 0.17 12.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EJP66919.1 - 0.0042 16.6 0.0 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EJP66919.1 - 0.009 16.4 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP66919.1 - 0.037 14.3 0.0 0.068 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJP66919.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EJP66919.1 - 0.07 12.4 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Septin TniB PF05621.11 EJP66919.1 - 0.072 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EJP66919.1 - 0.08 12.9 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EJP66919.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EJP66919.1 - 0.091 13.3 0.0 0.16 12.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EJP66919.1 - 0.11 12.3 0.1 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EJP66919.1 - 0.16 11.6 0.1 1.5 8.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF2742 PF10888.8 EJP66920.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) WD40 PF00400.32 EJP66921.1 - 1.6e-14 54.0 11.9 0.0004 21.1 0.0 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.6 EJP66921.1 - 0.034 14.7 0.0 3.9 8.1 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain Sigma70_r1_2 PF00140.20 EJP66921.1 - 0.083 12.9 0.6 0.19 11.8 0.6 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Mcl1_mid PF12341.8 EJP66922.1 - 3.5e-99 331.9 0.0 5e-97 324.8 0.0 2.4 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EJP66922.1 - 5.2e-20 71.4 0.5 4.2e-08 33.7 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP66922.1 - 1.2e-17 63.9 0.0 5.2e-05 23.5 0.0 6.6 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EJP66922.1 - 0.00023 20.3 0.0 0.00059 19.0 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WDCP PF15390.6 EJP66922.1 - 0.003 16.0 0.1 1.5 7.1 0.0 3.1 3 1 1 4 4 4 2 WD repeat and coiled-coil-containing protein family eIF2A PF08662.11 EJP66922.1 - 0.0074 16.2 0.3 0.12 12.3 0.1 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Pox_Ag35 PF03286.14 EJP66922.1 - 0.04 13.7 2.8 0.068 13.0 2.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ge1_WD40 PF16529.5 EJP66922.1 - 0.12 11.4 0.1 3.6 6.5 0.0 3.0 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DCX PF03607.17 EJP66922.1 - 0.18 11.9 0.1 3.9 7.6 0.0 3.0 2 1 1 3 3 3 0 Doublecortin Mis14 PF08641.12 EJP66922.1 - 0.36 11.2 5.1 0.66 10.3 5.1 1.4 1 0 0 1 1 1 0 Kinetochore protein Mis14 like CENP-B_dimeris PF09026.10 EJP66922.1 - 0.71 10.3 9.6 1.8 9.0 9.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HSF_DNA-bind PF00447.17 EJP66923.1 - 1.5e-29 102.5 1.0 2.3e-29 101.8 1.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding GREB1 PF15782.5 EJP66923.1 - 0.1 9.7 1.8 0.14 9.2 1.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC71L PF15374.6 EJP66924.1 - 0.0066 15.8 11.8 0.0082 15.5 11.8 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L Zip PF02535.22 EJP66924.1 - 2.9 7.0 5.7 4.3 6.5 5.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleo_P87 PF07267.11 EJP66924.1 - 3.6 6.3 7.3 4.1 6.1 7.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4407 PF14362.6 EJP66924.1 - 6.2 6.1 9.5 7.7 5.8 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) T2SSC PF11356.8 EJP66924.1 - 7.9 6.4 7.0 0.82 9.6 1.8 1.9 2 0 0 2 2 2 0 Type II secretion system protein C NICE-3 PF07406.11 EJP66925.1 - 0.00091 19.3 5.6 0.00094 19.2 0.1 2.7 3 0 0 3 3 3 1 NICE-3 protein DUF4129 PF13559.6 EJP66925.1 - 0.0011 19.2 0.0 0.003 17.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Yip1 PF04893.17 EJP66925.1 - 0.42 10.3 3.3 0.68 9.6 3.3 1.3 1 0 0 1 1 1 0 Yip1 domain Ndc1_Nup PF09531.10 EJP66926.1 - 8.1e-199 662.3 2.0 1.2e-198 661.7 2.0 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 EJP66927.1 - 3.6e-23 81.8 4.2 3.6e-23 81.8 4.2 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EJP66927.1 - 2e-10 40.5 0.9 4.8e-10 39.3 0.9 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EJP66927.1 - 0.0015 18.3 9.8 0.0085 15.8 9.8 2.2 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 EJP66927.1 - 0.012 15.4 0.2 0.03 14.1 0.2 1.8 1 0 0 1 1 1 0 Synaptobrevin DUF883 PF05957.13 EJP66927.1 - 0.047 14.3 9.4 0.11 13.1 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 EJP66927.1 - 0.084 13.1 2.3 8.9 6.6 0.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Nre_C PF04895.12 EJP66927.1 - 0.11 12.5 0.8 0.26 11.2 0.2 1.9 2 0 0 2 2 2 0 Archaeal Nre, C-terminal T2SSF PF00482.23 EJP66927.1 - 0.11 12.5 2.1 0.19 11.7 0.3 2.4 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein F T3SSipB PF16535.5 EJP66927.1 - 0.6 10.6 11.0 0.32 11.5 3.7 2.6 3 0 0 3 3 3 0 Type III cell invasion protein SipB ALG11_N PF15924.5 EJP66929.1 - 6.7e-82 274.6 0.0 9.1e-82 274.2 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EJP66929.1 - 3.8e-18 65.6 0.0 6.1e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EJP66929.1 - 6.7e-11 42.8 0.0 1.4e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EJP66929.1 - 0.0084 16.1 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 G_glu_transpept PF01019.21 EJP66930.1 - 5e-160 533.7 0.1 5.9e-160 533.4 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RRM_1 PF00076.22 EJP66931.1 - 1.9e-10 40.4 0.4 1.1e-06 28.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EJP66931.1 - 0.0038 17.3 0.2 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 Limkain b1 Flot PF15975.5 EJP66931.1 - 0.028 14.6 0.1 0.087 13.0 0.1 1.8 1 0 0 1 1 1 0 Flotillin Tubulin PF00091.25 EJP66932.1 - 7.4e-61 205.8 0.0 9.9e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EJP66932.1 - 6.6e-44 149.1 0.0 1e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EJP66932.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain Ribosomal_S19 PF00203.21 EJP66933.1 - 5.3e-33 112.8 0.3 7.4e-33 112.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 EpmC PF04315.12 EJP66933.1 - 0.054 13.2 0.0 3.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor P hydroxylase FliH PF02108.16 EJP66933.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH SET PF00856.28 EJP66934.1 - 0.0036 17.7 0.1 0.0052 17.2 0.1 1.3 1 0 0 1 1 1 1 SET domain RuBisCO_large_N PF02788.16 EJP66935.1 - 0.083 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain NUDIX PF00293.28 EJP66936.1 - 0.00037 20.5 0.0 0.00058 19.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GFO_IDH_MocA PF01408.22 EJP66937.1 - 3e-08 34.5 0.2 2.1e-07 31.8 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EJP66937.1 - 0.00074 19.5 0.1 0.0019 18.2 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain RNase_T PF00929.24 EJP66938.1 - 6.5e-25 88.6 0.1 7.4e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.16 EJP66939.1 - 1.2e-30 106.0 0.0 1.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EJP66939.1 - 1.1e-26 93.3 0.0 2e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EJP66939.1 - 6.2e-15 55.7 0.0 1.5e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EJP66939.1 - 4.8e-07 29.9 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HMG_box PF00505.19 EJP66941.1 - 4.7e-25 87.8 0.8 4.7e-25 87.8 0.8 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EJP66941.1 - 2.8e-18 66.2 1.3 2.8e-18 66.2 1.3 1.4 2 0 0 2 2 2 1 HMG-box domain Ccdc124 PF06244.12 EJP66941.1 - 0.0009 19.8 0.7 0.0024 18.4 0.0 1.8 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 EJP66941.1 - 0.013 15.5 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 EJP66941.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain Prp31_C PF09785.9 EJP66941.1 - 0.12 13.3 2.7 0.14 13.1 2.7 1.1 1 0 0 1 1 1 0 Prp31 C terminal domain CENP-H PF05837.12 EJP66942.1 - 1.3e-27 96.4 0.5 1.3e-27 96.4 0.5 2.4 2 1 0 2 2 2 1 Centromere protein H (CENP-H) ATG11 PF10377.9 EJP66943.1 - 1.1e-42 145.1 0.3 1.1e-42 145.1 0.3 4.0 3 1 0 4 4 4 1 Autophagy-related protein 11 DUF4201 PF13870.6 EJP66943.1 - 0.0015 18.3 12.9 0.0015 18.3 12.9 7.1 6 2 2 8 8 8 2 Domain of unknown function (DUF4201) Cleaved_Adhesin PF07675.11 EJP66943.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Cleaved Adhesin Domain FERM_f0 PF16511.5 EJP66943.1 - 0.016 15.5 0.1 1.1 9.6 0.0 3.1 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM UCH PF00443.29 EJP66944.1 - 1.9e-37 129.2 0.3 2.6e-33 115.6 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJP66944.1 - 8.7e-07 28.8 5.1 0.0056 16.3 4.2 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Stevor PF17410.2 EJP66944.1 - 0.034 13.7 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Ctr PF04145.15 EJP66944.1 - 1.1 9.9 2.8 0.77 10.4 0.1 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Macoilin PF09726.9 EJP66944.1 - 2.1 6.8 11.7 0.0077 14.9 1.4 1.8 2 0 0 2 2 2 0 Macoilin family Fringe PF02434.16 EJP66945.1 - 4e-05 23.2 0.2 0.00017 21.1 0.2 1.9 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 EJP66945.1 - 0.00031 20.6 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 PAN domain Zn_clus PF00172.18 EJP66946.1 - 0.0043 17.1 4.8 0.0077 16.3 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CW_binding_1 PF01473.20 EJP66946.1 - 0.064 13.6 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat Inj_translocase PF16928.5 EJP66946.1 - 0.066 12.7 1.5 0.11 11.9 1.5 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome SUIM_assoc PF16619.5 EJP66946.1 - 0.35 11.0 14.1 0.021 14.9 7.3 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cu-oxidase_3 PF07732.15 EJP66947.1 - 4.3e-40 136.4 0.8 4.3e-40 136.4 0.8 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP66947.1 - 2.7e-36 124.3 10.4 1.6e-33 115.4 0.6 4.1 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 EJP66947.1 - 2.2e-28 99.4 0.3 1.8e-26 93.2 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.14 EJP66948.1 - 5.3e-34 118.0 3.9 1.3e-32 113.4 1.4 2.7 1 1 1 2 2 2 2 Phosphoesterase family VIT1 PF01988.19 EJP66949.1 - 1.2e-57 195.2 2.1 1.5e-57 194.9 2.1 1.1 1 0 0 1 1 1 1 VIT family FAD_binding_3 PF01494.19 EJP66950.1 - 3.4e-22 79.2 1.2 3.4e-20 72.6 1.2 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJP66950.1 - 4.9e-05 23.1 1.2 0.013 15.1 1.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP66950.1 - 0.0003 20.1 0.0 0.0039 16.5 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EJP66950.1 - 0.00051 19.2 2.4 0.016 14.3 0.3 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.10 EJP66950.1 - 0.00075 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EJP66950.1 - 0.016 15.4 0.5 0.16 12.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EJP66950.1 - 0.02 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 EJP66950.1 - 0.055 12.7 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 EJP66950.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EJP66950.1 - 0.099 11.5 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DUF1289 PF06945.13 EJP66950.1 - 0.28 11.0 1.0 23 4.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Complex1_49kDa PF00346.19 EJP66951.1 - 4.5e-124 412.9 0.0 6.3e-124 412.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EJP66951.1 - 0.0059 15.6 0.0 0.0088 15.0 0.0 1.4 1 0 0 1 1 1 1 Nickel-dependent hydrogenase MSC PF09402.10 EJP66952.1 - 4e-115 384.9 0.0 6.6e-115 384.2 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain ABC_tran PF00005.27 EJP66952.1 - 9.9e-41 139.5 0.0 1.8e-19 70.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 EJP66952.1 - 1e-26 94.2 23.9 1.4e-26 93.8 12.5 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region HeH PF12949.7 EJP66952.1 - 2.1e-14 52.9 0.1 4.7e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain AAA_21 PF13304.6 EJP66952.1 - 1.3e-09 38.4 1.1 0.00047 20.1 0.0 4.4 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP66952.1 - 8.4e-09 35.2 1.0 0.016 14.6 0.1 4.0 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EJP66952.1 - 3.5e-06 27.5 0.3 0.12 12.7 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EJP66952.1 - 2.7e-05 23.8 0.3 0.21 11.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP66952.1 - 0.0014 18.9 0.0 0.59 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EJP66952.1 - 0.0073 15.4 0.2 0.37 9.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EJP66952.1 - 0.043 13.7 0.1 7.3 6.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 EJP66952.1 - 0.05 13.7 0.1 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EJP66952.1 - 0.055 13.4 5.7 3.2 7.6 0.0 3.4 4 0 0 4 4 4 0 NACHT domain SbcCD_C PF13558.6 EJP66952.1 - 0.062 13.5 0.1 0.062 13.5 0.1 3.4 4 1 0 4 4 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 EJP66952.1 - 0.069 12.5 0.1 6.3 6.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Thymopoietin PF08198.11 EJP66952.1 - 0.074 12.7 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Thymopoietin protein DUF2075 PF09848.9 EJP66952.1 - 0.092 12.0 0.4 0.72 9.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CysG_dimeriser PF10414.9 EJP66952.1 - 0.14 11.9 0.7 22 4.9 0.0 2.8 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region DUF87 PF01935.17 EJP66952.1 - 0.57 10.2 4.3 0.58 10.2 0.1 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Mt_ATP-synt_B PF05405.14 EJP66953.1 - 5.2e-53 179.0 6.8 6.6e-53 178.7 6.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CBF PF03914.17 EJP66954.1 - 1.1e-33 116.7 2.0 1.5e-33 116.3 0.9 1.9 2 0 0 2 2 2 1 CBF/Mak21 family TAL_FSA PF00923.19 EJP66954.1 - 0.05 12.9 0.0 0.66 9.3 0.0 2.1 2 0 0 2 2 2 0 Transaldolase/Fructose-6-phosphate aldolase MFS_1 PF07690.16 EJP66955.1 - 3.3e-39 134.8 59.5 3.3e-39 134.8 59.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP66955.1 - 6.7e-17 61.1 17.8 1.7e-16 59.8 14.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EJP66955.1 - 2.7e-13 49.6 13.9 2.7e-13 49.6 13.9 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter CorA PF01544.18 EJP66956.1 - 8.6e-38 130.3 0.1 1.6e-37 129.4 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Guanylate_kin PF00625.21 EJP66956.1 - 0.17 11.5 0.4 0.37 10.5 0.4 1.5 1 0 0 1 1 1 0 Guanylate kinase NICE-1 PF15845.5 EJP66956.1 - 1.5 9.7 9.8 0.25 12.2 2.7 2.8 3 0 0 3 3 3 0 Cysteine-rich C-terminal 1 family CSTF2_hinge PF14327.6 EJP66957.1 - 1.3e-33 115.3 2.6 2.1e-33 114.6 1.9 1.8 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EJP66957.1 - 1.3e-21 76.2 0.0 2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EJP66957.1 - 8.3e-08 31.7 4.2 8.3e-08 31.7 4.2 3.7 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.6 EJP66957.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP66957.1 - 0.016 15.3 0.1 0.16 12.1 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif Spo7_2_N PF15407.6 EJP66957.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 FliG_M PF14841.6 EJP66957.1 - 0.36 11.1 2.0 0.58 10.4 0.3 2.2 2 1 1 3 3 3 0 FliG middle domain FTA2 PF13095.6 EJP66958.1 - 0.022 14.4 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HABP4_PAI-RBP1 PF04774.15 EJP66959.1 - 0.00071 20.4 0.7 0.0011 19.9 0.7 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family DUF3246 PF11596.8 EJP66959.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SH2_2 PF14633.6 EJP66960.1 - 2.3e-85 285.4 0.0 5.3e-85 284.2 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 EJP66960.1 - 3.7e-40 136.9 1.1 3.7e-40 136.9 1.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EJP66960.1 - 1.3e-30 105.8 0.0 2.9e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EJP66960.1 - 2.1e-30 105.5 0.0 1.4e-29 102.8 0.0 2.5 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EJP66960.1 - 1.6e-19 70.2 30.5 1.6e-19 70.2 30.5 5.8 5 1 1 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 EJP66960.1 - 5.3e-06 27.3 0.2 4.3e-05 24.3 0.2 2.8 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 EJP66960.1 - 4.5e-05 23.5 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain S1 PF00575.23 EJP66960.1 - 0.00017 21.8 0.0 0.00042 20.6 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 EJP66960.1 - 0.00038 20.6 0.0 0.002 18.4 0.0 2.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 EJP66960.1 - 0.078 13.4 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Tex protein YqgF-like domain Pkinase PF00069.25 EJP66961.1 - 2e-64 217.5 0.0 2.5e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66961.1 - 1e-38 133.1 0.0 1.3e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP66961.1 - 0.00045 19.1 0.0 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EJP66961.1 - 0.00048 19.5 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EJP66961.1 - 0.016 14.2 0.1 0.022 13.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HAD_2 PF13419.6 EJP66962.1 - 3.9e-11 43.4 0.0 8.1e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP66962.1 - 1.6e-10 41.6 0.0 1.1e-06 29.2 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP66962.1 - 6.7e-06 26.1 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EJP66962.1 - 0.0038 17.7 0.1 0.024 15.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EJP66962.1 - 0.17 11.5 0.1 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase FUSC_2 PF13515.6 EJP66964.1 - 1.2e-25 90.0 7.9 1.2e-25 90.0 7.9 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EJP66964.1 - 0.00059 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EJP66964.1 - 0.0024 16.8 21.5 0.13 11.0 7.5 4.9 6 1 0 6 6 6 3 Aluminium activated malate transporter FUSC PF04632.12 EJP66964.1 - 0.02 13.4 17.5 0.013 14.0 6.1 3.3 3 1 0 3 3 3 0 Fusaric acid resistance protein family ArAE_2_N PF10337.9 EJP66964.1 - 0.027 13.5 0.3 0.027 13.5 0.3 2.5 2 1 1 3 3 3 0 Putative ER transporter, 6TM, N-terminal DNA_pol_E_B PF04042.16 EJP66965.1 - 3.5e-61 206.2 0.0 6.6e-61 205.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B APH PF01636.23 EJP66967.1 - 2.6e-17 63.5 0.1 7.4e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP66967.1 - 2.7e-10 40.2 0.0 6.5e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EJP66967.1 - 0.0018 17.9 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 EJP66967.1 - 0.03 13.7 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 EJP66967.1 - 0.17 10.7 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 EJP66968.1 - 8.2e-75 251.6 0.0 1.2e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66968.1 - 1.7e-38 132.4 0.0 2.6e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EJP66968.1 - 3.2e-18 66.3 1.7 2.7e-14 53.6 1.7 3.3 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EJP66968.1 - 3.7e-15 55.8 0.4 7.3e-15 54.8 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EJP66968.1 - 1.2e-06 28.1 0.0 3.9e-06 26.4 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EJP66968.1 - 8.5e-05 21.7 0.2 0.00025 20.1 0.3 1.7 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 EJP66968.1 - 0.00047 19.8 0.4 0.00096 18.8 0.4 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 EJP66968.1 - 0.004 16.0 0.1 0.0062 15.4 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 EJP66968.1 - 0.063 13.2 0.3 0.29 11.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family GFA PF04828.14 EJP66969.1 - 0.0086 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Bys1 PF04681.12 EJP66970.1 - 2.4e-14 53.5 0.0 2.9e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Erf4 PF10256.9 EJP66971.1 - 4.7e-38 129.9 0.0 5.9e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family APH PF01636.23 EJP66972.1 - 2.2e-09 37.6 0.2 6.3e-09 36.1 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP66972.1 - 0.0021 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase NTPase_I-T PF01931.18 EJP66973.1 - 2.5e-54 183.5 0.0 2.9e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 AA_permease_2 PF13520.6 EJP66974.1 - 1.2e-49 169.3 39.9 1.6e-49 168.9 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP66974.1 - 1.2e-25 90.0 33.8 1.6e-25 89.7 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease Herpes_LMP1 PF05297.11 EJP66975.1 - 0.019 14.2 0.4 0.032 13.5 0.4 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4337 PF14235.6 EJP66976.1 - 0.0014 18.8 1.5 0.13 12.4 1.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4337) Sigma70_ner PF04546.13 EJP66976.1 - 0.071 13.0 2.8 4.3 7.2 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4203 PF13886.6 EJP66977.1 - 1.2e-51 175.3 29.6 1.6e-51 174.9 29.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2149 PF09919.9 EJP66977.1 - 0.16 12.2 1.4 1.3 9.3 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) STE3 PF02076.15 EJP66978.1 - 1.2e-64 218.4 18.3 1.5e-64 218.1 18.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.21 EJP66978.1 - 0.45 9.8 13.9 0.68 9.2 13.9 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SSB PF00436.25 EJP66979.1 - 2.7e-20 72.3 0.2 3.2e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family BA14K PF07886.11 EJP66979.1 - 0.11 12.4 0.5 0.23 11.4 0.5 1.6 1 0 0 1 1 1 0 BA14K-like protein GSH_synth_ATP PF03917.17 EJP66980.1 - 1.8e-120 402.2 0.0 7.3e-119 396.9 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EJP66980.1 - 1.4e-33 115.4 0.0 2.6e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 EJP66981.1 - 6.7e-45 153.3 0.2 1e-44 152.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP66981.1 - 1.3e-22 80.2 0.2 5.1e-22 78.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP66981.1 - 2.1e-10 40.8 0.1 9.8e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EJP66981.1 - 2.5e-05 24.1 2.1 0.048 13.3 0.0 3.4 3 0 0 3 3 3 2 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EJP66981.1 - 0.0012 18.1 0.1 0.0025 17.1 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase EF-hand_2 PF09068.11 EJP66981.1 - 0.09 12.9 0.1 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 EF hand Aminotran_1_2 PF00155.21 EJP66982.1 - 2.3e-80 270.5 0.0 3e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EJP66982.1 - 4.4e-05 22.2 0.0 6.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EJP66982.1 - 0.0015 17.6 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EJP66982.1 - 0.0026 17.1 0.2 0.0046 16.3 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Preseq_ALAS PF09029.10 EJP66982.1 - 1.7 9.2 8.6 28 5.2 8.6 2.6 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence Dynamitin PF04912.14 EJP66983.1 - 0.0085 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Dynamitin Zn_clus PF00172.18 EJP66983.1 - 0.0092 16.1 11.6 0.016 15.4 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_6 PF13480.7 EJP66983.1 - 0.64 10.2 3.1 5.6 7.1 0.0 3.2 2 2 2 4 4 4 0 Acetyltransferase (GNAT) domain HK PF02110.15 EJP66984.1 - 4.5e-73 245.7 5.6 2.4e-72 243.3 5.6 2.0 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EJP66984.1 - 9.6e-58 194.5 3.1 2.3e-57 193.2 3.1 1.7 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 EJP66984.1 - 0.0014 18.1 0.1 0.035 13.5 0.1 2.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 EJP66984.1 - 0.0015 18.0 1.5 0.0049 16.4 1.5 2.0 1 1 0 1 1 1 1 Carbohydrate kinase Pyr_redox_2 PF07992.14 EJP66985.1 - 2.8e-45 154.8 0.0 4.5e-45 154.1 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP66985.1 - 8.3e-14 51.9 0.0 2.1e-11 44.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP66985.1 - 1.6e-06 27.6 0.1 8.1e-05 22.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP66985.1 - 0.036 13.2 0.1 1 8.4 0.1 2.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 EJP66985.1 - 0.095 13.0 0.0 4.9 7.5 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Eno-Rase_NADH_b PF12242.8 EJP66985.1 - 0.13 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BP28CT PF08146.12 EJP66986.1 - 5.7e-41 140.0 0.0 9.4e-40 136.0 0.0 2.9 2 1 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EJP66986.1 - 3.1e-23 82.3 0.2 3.1e-23 82.3 0.2 5.9 7 1 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 EJP66986.1 - 4.1e-06 26.6 10.4 0.0091 16.2 0.1 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EJP66986.1 - 6.5e-06 26.5 12.0 0.71 10.3 0.0 6.7 5 1 2 7 7 7 2 HEAT repeats TAF6_C PF07571.13 EJP66986.1 - 0.089 13.1 0.8 5.2 7.5 0.0 4.2 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EJP66986.1 - 0.094 12.9 2.6 2.1 8.5 0.1 4.1 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EJP66986.1 - 3.5 8.2 12.7 5.1 7.7 0.1 6.3 5 1 0 5 5 5 0 HEAT-like repeat Lipase_GDSL_2 PF13472.6 EJP66987.1 - 5.5e-21 75.8 0.0 7.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EJP66987.1 - 2e-15 57.3 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF919 PF06034.11 EJP66988.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Isochorismatase PF00857.20 EJP66989.1 - 1.3e-18 67.8 1.5 2.1e-18 67.1 1.5 1.3 1 0 0 1 1 1 1 Isochorismatase family DUF3239 PF11580.8 EJP66989.1 - 0.092 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) AAA_5 PF07728.14 EJP66990.1 - 1e-122 404.6 0.0 5.7e-21 75.0 0.0 9.9 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EJP66990.1 - 4.2e-51 171.6 8.4 1.1e-21 77.0 0.1 5.7 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 EJP66990.1 - 1.9e-30 105.1 5.8 3.1e-30 104.4 0.1 4.1 4 0 0 4 4 3 1 Midasin AAA lid domain AAA PF00004.29 EJP66990.1 - 3.5e-29 101.9 0.1 0.00025 21.5 0.0 7.7 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EJP66990.1 - 7.8e-29 100.2 0.0 1.2e-09 38.1 0.0 6.9 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EJP66990.1 - 4.7e-28 97.9 0.9 6.7e-06 25.7 0.0 7.0 6 1 0 6 6 6 4 P-loop containing dynein motor region AAA_16 PF13191.6 EJP66990.1 - 3.8e-26 92.5 22.0 8e-06 26.3 0.3 10.4 9 3 0 9 9 8 5 AAA ATPase domain Dynein_heavy PF03028.15 EJP66990.1 - 2e-22 79.5 0.0 0.0031 17.6 0.0 8.6 7 1 1 8 8 7 4 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 EJP66990.1 - 7.5e-20 71.6 5.1 0.0025 18.1 0.0 8.6 10 0 0 10 10 6 3 AAA domain AAA_6 PF12774.7 EJP66990.1 - 3.3e-19 69.0 0.0 0.0091 15.0 0.0 7.8 8 0 0 8 8 7 4 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 EJP66990.1 - 6.9e-19 68.2 0.0 0.01 15.5 0.0 6.1 6 0 0 6 6 5 5 Sigma-54 interaction domain TsaE PF02367.17 EJP66990.1 - 9.6e-16 57.9 4.3 0.023 14.7 0.1 6.0 6 0 0 6 6 5 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EJP66990.1 - 1.5e-15 57.4 0.0 0.15 12.1 0.0 7.7 7 0 0 7 7 7 3 AAA domain AAA_33 PF13671.6 EJP66990.1 - 1.7e-13 50.9 0.1 0.13 12.4 0.0 6.4 6 0 0 6 6 5 4 AAA domain RsgA_GTPase PF03193.16 EJP66990.1 - 1.8e-13 50.8 0.3 0.053 13.4 0.0 6.2 6 0 0 6 6 5 3 RsgA GTPase RNA_helicase PF00910.22 EJP66990.1 - 2.5e-13 50.4 1.7 0.071 13.5 0.0 6.3 6 0 0 6 6 6 3 RNA helicase NACHT PF05729.12 EJP66990.1 - 8.6e-13 48.5 6.5 0.089 12.7 0.3 6.4 5 0 0 5 5 5 4 NACHT domain Sigma54_activ_2 PF14532.6 EJP66990.1 - 1.8e-12 47.5 0.2 0.0024 18.0 0.0 6.2 6 0 0 6 6 5 2 Sigma-54 interaction domain AAA_30 PF13604.6 EJP66990.1 - 5.5e-12 45.8 0.1 0.066 12.9 0.0 7.5 6 2 0 6 6 6 2 AAA domain AAA_18 PF13238.6 EJP66990.1 - 1.4e-11 45.1 14.0 0.058 13.9 0.0 7.8 9 0 0 9 9 6 3 AAA domain T2SSE PF00437.20 EJP66990.1 - 1.6e-11 43.8 0.1 0.018 14.1 0.0 5.5 5 0 0 5 5 5 3 Type II/IV secretion system protein RuvB_N PF05496.12 EJP66990.1 - 4.3e-11 42.8 7.3 0.015 15.1 0.0 7.5 8 0 0 8 8 6 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EJP66990.1 - 5e-09 36.0 0.8 1 8.9 0.0 5.5 5 0 0 5 5 5 1 AAA domain DUF815 PF05673.13 EJP66990.1 - 6.4e-09 35.3 0.2 0.26 10.4 0.0 4.9 5 0 0 5 5 5 2 Protein of unknown function (DUF815) ABC_tran PF00005.27 EJP66990.1 - 1.3e-08 35.4 17.6 0.0036 17.8 0.0 7.1 8 0 0 8 8 5 2 ABC transporter AAA_28 PF13521.6 EJP66990.1 - 2.5e-08 34.3 3.2 3.8 7.7 0.0 6.2 5 0 0 5 5 5 0 AAA domain Zeta_toxin PF06414.12 EJP66990.1 - 4.8e-08 32.5 7.7 0.49 9.6 0.0 6.6 8 0 0 8 8 5 2 Zeta toxin IstB_IS21 PF01695.17 EJP66990.1 - 6.8e-08 32.4 0.3 1.1 8.9 0.0 6.0 6 0 0 6 6 6 1 IstB-like ATP binding protein NTPase_1 PF03266.15 EJP66990.1 - 2.1e-07 31.0 8.2 1.7 8.6 0.1 6.6 6 0 0 6 6 6 2 NTPase Rad17 PF03215.15 EJP66990.1 - 3.1e-07 30.5 1.6 0.89 9.4 0.0 5.4 5 0 0 5 5 5 2 Rad17 P-loop domain ATPase_2 PF01637.18 EJP66990.1 - 7.2e-07 29.3 0.1 6.1 6.7 0.0 6.6 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EJP66990.1 - 8.2e-07 28.7 0.3 17 5.2 0.0 6.2 6 0 0 6 6 6 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EJP66990.1 - 9e-07 28.7 4.0 0.068 12.9 0.0 4.9 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 EJP66990.1 - 1e-06 28.3 0.9 17 4.7 0.0 7.0 7 0 0 7 7 7 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 EJP66990.1 - 1.7e-06 27.8 4.3 0.35 10.5 0.0 4.8 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain TniB PF05621.11 EJP66990.1 - 4e-06 26.4 0.1 7.1 6.0 0.0 5.6 6 0 0 6 6 4 0 Bacterial TniB protein AAA_19 PF13245.6 EJP66990.1 - 1.3e-05 25.5 7.8 6.1 7.2 0.0 6.8 7 0 0 7 7 5 0 AAA domain TIP49 PF06068.13 EJP66990.1 - 1.4e-05 24.4 1.0 0.97 8.6 0.0 4.7 5 0 0 5 5 5 1 TIP49 P-loop domain MMR_HSR1 PF01926.23 EJP66990.1 - 1.5e-05 25.0 0.2 19 5.4 0.0 5.7 5 0 0 5 5 5 0 50S ribosome-binding GTPase Roc PF08477.13 EJP66990.1 - 1.5e-05 25.1 1.4 7.3 6.8 0.0 5.5 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EJP66990.1 - 2.1e-05 24.3 2.9 3.3 7.4 0.5 6.4 6 1 0 6 6 6 0 AAA domain Bac_DnaA PF00308.18 EJP66990.1 - 3.5e-05 23.8 1.1 3.7 7.3 0.1 5.3 6 0 0 6 6 5 0 Bacterial dnaA protein KAP_NTPase PF07693.14 EJP66990.1 - 0.00016 21.0 0.0 0.92 8.7 0.0 5.0 5 0 0 5 5 5 1 KAP family P-loop domain ResIII PF04851.15 EJP66990.1 - 0.00016 21.7 10.8 0.14 12.2 0.0 6.0 6 0 0 6 6 5 1 Type III restriction enzyme, res subunit dNK PF01712.19 EJP66990.1 - 0.00063 19.7 2.4 46 3.8 0.0 5.3 5 0 0 5 5 5 0 Deoxynucleoside kinase CbiA PF01656.23 EJP66990.1 - 0.0013 18.8 1.4 36 4.4 0.0 5.4 5 0 0 5 5 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain CPT PF07931.12 EJP66990.1 - 0.0016 18.3 0.6 22 4.8 0.0 5.2 4 1 0 4 4 4 0 Chloramphenicol phosphotransferase-like protein GAF_2 PF13185.6 EJP66990.1 - 0.0022 18.3 0.1 1.2 9.4 0.0 3.4 2 0 0 2 2 2 1 GAF domain NB-ARC PF00931.22 EJP66990.1 - 0.0028 16.9 5.4 2.4 7.3 0.0 5.0 5 0 0 5 5 5 1 NB-ARC domain DAP3 PF10236.9 EJP66990.1 - 0.0037 16.5 1.9 2.3 7.3 0.0 4.3 4 0 0 4 4 4 1 Mitochondrial ribosomal death-associated protein 3 Thymidylate_kin PF02223.17 EJP66990.1 - 0.0043 16.8 6.7 0.46 10.1 0.0 5.5 6 0 0 6 6 5 1 Thymidylate kinase Viral_helicase1 PF01443.18 EJP66990.1 - 0.006 16.4 0.3 37 4.0 0.1 4.7 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase VWA PF00092.28 EJP66990.1 - 0.008 16.4 0.7 0.025 14.8 0.1 2.2 2 0 0 2 2 1 1 von Willebrand factor type A domain AAA_8 PF12780.7 EJP66990.1 - 0.013 14.8 0.1 16 4.7 0.0 4.6 5 0 0 5 5 4 0 P-loop containing dynein motor region D4 DEAD PF00270.29 EJP66990.1 - 0.023 14.4 0.4 10 5.8 0.0 3.9 4 0 0 4 4 4 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 EJP66990.1 - 0.024 14.3 0.0 42 3.7 0.0 4.0 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain VWA_2 PF13519.6 EJP66990.1 - 0.028 15.1 0.1 0.19 12.4 0.1 2.6 1 0 0 1 1 1 0 von Willebrand factor type A domain ATP_bind_1 PF03029.17 EJP66990.1 - 0.034 13.9 5.8 2.8 7.7 0.0 4.8 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 EJP66990.1 - 0.083 12.2 0.2 13 5.0 0.0 3.8 4 0 0 4 4 4 0 KaiC PhoH PF02562.16 EJP66990.1 - 0.088 12.2 0.9 8.5 5.8 0.0 4.2 5 0 0 5 5 4 0 PhoH-like protein cobW PF02492.19 EJP66990.1 - 0.09 12.4 7.4 68 3.0 0.1 5.8 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.22 EJP66990.1 - 0.1 12.7 0.7 13 5.9 0.0 3.7 3 0 0 3 3 3 0 Shikimate kinase PRK PF00485.18 EJP66990.1 - 0.11 12.2 0.2 18 5.0 0.0 3.7 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 EJP66990.1 - 3.1 7.7 8.2 78 3.2 0.1 4.8 6 0 0 6 6 4 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_L12 PF00542.19 EJP66991.1 - 9.8e-21 73.9 5.1 9.8e-21 73.9 5.1 2.5 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EJP66991.1 - 4.4e-12 45.5 12.4 4.4e-12 45.5 12.4 2.9 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 EJP66991.1 - 0.032 14.0 0.7 0.11 12.3 0.2 2.1 2 1 0 2 2 2 0 Stage VI sporulation protein F DAHP_snth_FXD PF18152.1 EJP66991.1 - 0.16 11.8 0.8 0.36 10.7 0.4 1.9 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain CTK3 PF12243.8 EJP66992.1 - 6.6e-48 161.8 0.0 9.6e-48 161.3 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EJP66992.1 - 1.3e-18 66.9 10.0 1.3e-18 66.9 10.0 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Abp2 PF09441.10 EJP66992.1 - 0.082 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 ARS binding protein 2 LID PF17916.1 EJP66992.1 - 0.084 12.5 0.6 0.19 11.4 0.6 1.6 1 0 0 1 1 1 0 LIM interaction domain (LID) Flu_C_NS2 PF03555.14 EJP66992.1 - 0.16 12.2 0.8 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) P5CR_dimer PF14748.6 EJP66993.1 - 5.4e-33 113.3 3.3 5.4e-33 113.3 3.3 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EJP66993.1 - 5.2e-13 49.4 2.1 2.3e-12 47.3 2.1 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Hat1_N PF10394.9 EJP66994.1 - 2.1e-46 158.1 0.0 3.3e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus UBA2_C PF16195.5 EJP66994.1 - 0.038 14.7 0.6 0.072 13.8 0.6 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Acetyltransf_10 PF13673.7 EJP66994.1 - 0.093 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF515 PF04415.12 EJP66995.1 - 0.66 8.3 0.0 0.66 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF515) LMBR1 PF04791.16 EJP66996.1 - 1.7e-65 221.9 0.0 2e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Pkinase PF00069.25 EJP66998.1 - 1e-74 251.2 0.0 1.4e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP66998.1 - 5.4e-31 107.8 0.0 2.9e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EJP66998.1 - 3.2e-06 26.7 0.1 1.4 8.2 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EJP66998.1 - 0.01 14.6 0.0 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Thump_like PF18096.1 EJP66998.1 - 0.012 15.6 0.1 0.032 14.2 0.1 1.7 1 0 0 1 1 1 0 THUMP domain-like Kdo PF06293.14 EJP66998.1 - 0.036 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP66998.1 - 0.093 12.6 0.0 1.6 8.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EJP66998.1 - 0.22 10.4 0.6 0.95 8.3 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Pox_P4B PF03292.14 EJP66999.1 - 0.078 11.2 0.0 0.094 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein DUF1926 PF09095.11 EJP66999.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) FOXP-CC PF16159.5 EJP66999.1 - 0.21 12.2 4.1 0.68 10.6 2.1 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain PDZ_6 PF17820.1 EJP67000.1 - 6.8e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_M61 PF05299.12 EJP67000.1 - 0.00014 22.3 0.5 0.0035 17.7 0.5 2.4 1 1 0 1 1 1 1 M61 glycyl aminopeptidase BSP PF04450.12 EJP67000.1 - 0.00058 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase of plants and bacteria PDZ_2 PF13180.6 EJP67000.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 EJP67000.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain SprT-like PF10263.9 EJP67000.1 - 0.21 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 SprT-like family adh_short PF00106.25 EJP67001.1 - 1.6e-25 89.7 0.1 2e-25 89.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP67001.1 - 8.9e-23 81.1 0.4 1.1e-22 80.8 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF460 PF04312.13 EJP67001.1 - 2.5e-06 27.2 0.1 4e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF460) KR PF08659.10 EJP67001.1 - 0.0001 22.3 0.1 0.00017 21.6 0.1 1.4 1 1 0 1 1 1 1 KR domain C2 PF00168.30 EJP67002.1 - 2.8e-24 85.4 0.0 4.3e-13 49.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain LEA_3 PF03242.13 EJP67002.1 - 0.026 15.2 0.2 0.083 13.6 0.2 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant protein T3SS_needle_F PF09392.10 EJP67002.1 - 0.071 13.3 0.4 2.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Phospholip_A2_3 PF09056.11 EJP67003.1 - 3e-27 95.5 3.9 4.4e-27 94.9 3.9 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Maf1 PF09174.10 EJP67005.1 - 5e-58 196.1 0.0 6.3e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 EJP67006.1 - 3.3e-50 169.7 0.5 3.9e-50 169.5 0.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.21 EJP67007.1 - 7e-07 28.7 0.0 9.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 EJP67008.1 - 2.2e-07 30.5 0.0 2.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EJP67008.1 - 5.1e-06 26.6 6.8 0.00078 19.4 0.9 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EJP67008.1 - 6.4e-06 25.7 0.0 9.1e-05 21.9 0.0 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EJP67008.1 - 0.00034 19.5 0.0 0.00048 19.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EJP67008.1 - 0.0024 17.5 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EJP67008.1 - 0.076 12.3 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pex2_Pex12 PF04757.14 EJP67009.1 - 1.2e-39 136.3 2.1 1.5e-39 136.0 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EJP67009.1 - 2.8e-12 46.3 8.6 4.2e-12 45.7 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP67009.1 - 1.2e-11 44.7 9.1 1.9e-11 44.1 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EJP67009.1 - 3.4e-11 42.8 5.5 5e-11 42.3 5.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP67009.1 - 2.3e-10 40.2 6.6 3.3e-10 39.6 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP67009.1 - 2e-08 34.1 8.1 3.8e-08 33.2 8.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EJP67009.1 - 9.5e-08 31.8 6.9 1.5e-07 31.2 6.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EJP67009.1 - 2.7e-07 30.5 5.0 4.3e-07 29.8 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EJP67009.1 - 8.4e-07 29.2 6.2 1.5e-06 28.4 6.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EJP67009.1 - 7e-06 26.1 8.5 1.1e-05 25.5 8.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EJP67009.1 - 0.0009 19.1 2.4 0.0017 18.2 2.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EJP67009.1 - 0.0018 18.4 5.6 0.003 17.6 5.6 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EJP67009.1 - 0.018 14.8 3.4 0.036 13.8 3.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 EJP67009.1 - 0.11 12.3 8.1 0.24 11.2 8.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-LYAR PF08790.11 EJP67010.1 - 3.4e-14 52.4 2.6 3.4e-14 52.4 2.6 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Hydrolase_4 PF12146.8 EJP67011.1 - 3.3e-16 59.3 0.0 1.2e-11 44.3 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP67011.1 - 3e-09 36.9 0.1 2.4e-06 27.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP67011.1 - 4.6e-05 24.1 0.0 0.00012 22.8 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EJP67011.1 - 0.00018 21.2 0.0 0.00059 19.6 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.12 EJP67011.1 - 0.0057 15.4 0.0 1.7 7.2 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DUF818 PF05677.12 EJP67011.1 - 0.0081 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Thioesterase PF00975.20 EJP67011.1 - 0.03 14.4 0.0 0.23 11.6 0.0 2.0 1 1 1 2 2 2 0 Thioesterase domain Peptidase_S9 PF00326.21 EJP67011.1 - 0.031 13.7 0.0 0.2 11.1 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.11 EJP67011.1 - 0.058 13.3 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal R3H PF01424.22 EJP67012.1 - 3.3e-14 52.6 0.7 6.4e-14 51.7 0.1 1.8 2 0 0 2 2 2 1 R3H domain Ole-e-6 PF09253.10 EJP67012.1 - 9.2 6.3 10.2 12 5.9 0.1 2.5 2 0 0 2 2 2 0 Pollen allergen ole e 6 WSC PF01822.19 EJP67013.1 - 2.3e-73 242.4 67.9 6e-18 64.8 5.0 5.5 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 EJP67013.1 - 1.3e-26 93.3 0.0 3.8e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EJP67013.1 - 7.3e-22 77.5 0.0 2e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Big_10 PF17964.1 EJP67013.1 - 0.014 15.4 0.9 0.032 14.2 0.9 1.5 1 0 0 1 1 1 0 Bacterial Ig domain Macro_2 PF14519.6 EJP67013.1 - 0.056 12.8 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Macro-like domain COesterase PF00135.28 EJP67014.1 - 2.2e-91 307.3 0.0 3.5e-90 303.3 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EJP67014.1 - 3.8e-06 26.9 0.0 1.2e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold MPC PF03650.13 EJP67015.1 - 1.1e-37 128.6 0.0 1.3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers CPSase_L_D2 PF02786.17 EJP67016.1 - 6.6e-81 270.8 0.3 1e-80 270.2 0.3 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EJP67016.1 - 6.8e-68 228.3 0.0 1.2e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_C PF02785.19 EJP67016.1 - 1.1e-31 109.1 0.0 4.2e-31 107.3 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EJP67016.1 - 2.7e-28 99.3 0.0 4.7e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_carb_N PF00289.22 EJP67016.1 - 1.1e-18 67.8 0.0 2.5e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EJP67016.1 - 1.5e-18 66.4 3.2 3.5e-18 65.2 1.3 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EJP67016.1 - 5.2e-10 39.0 0.2 4e-05 23.4 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EJP67016.1 - 5.6e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EJP67016.1 - 2.4e-07 30.5 0.1 5e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EJP67016.1 - 8.4e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 EJP67016.1 - 8.8e-05 21.8 0.1 0.025 13.8 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 EJP67016.1 - 0.00016 21.3 0.1 0.00077 19.1 0.0 2.1 2 1 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 EJP67016.1 - 0.0029 18.3 0.1 7.4 7.3 0.0 3.3 3 0 0 3 3 3 2 HlyD family secretion protein NQRA PF05896.11 EJP67016.1 - 0.0091 15.5 0.2 0.016 14.7 0.2 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF3572 PF12096.8 EJP67016.1 - 0.013 15.7 0.1 0.035 14.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) ATP-grasp_4 PF13535.6 EJP67016.1 - 0.016 14.8 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain DUF2118 PF09891.9 EJP67016.1 - 0.045 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 EJP67016.1 - 0.05 12.9 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 EJP67016.1 - 0.12 12.3 0.2 0.38 10.7 0.2 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Barttin PF15462.6 EJP67017.1 - 0.14 11.9 3.5 0.077 12.8 1.3 1.8 1 1 1 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Aldedh PF00171.22 EJP67018.1 - 5.1e-78 262.6 0.0 6.5e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RCR PF12273.8 EJP67018.1 - 2.7e-19 70.0 18.1 1.5e-18 67.6 18.1 2.1 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.11 EJP67018.1 - 0.0034 17.3 1.5 0.0034 17.3 1.5 1.9 2 0 0 2 2 2 1 Human adenovirus early E3A glycoprotein Rhabdo_glycop PF00974.18 EJP67018.1 - 4.1 5.8 6.1 0.43 9.0 1.5 1.5 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein Zn_clus PF00172.18 EJP67019.1 - 0.00045 20.3 12.4 0.00099 19.2 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.21 EJP67020.1 - 2.1e-27 95.5 0.0 3.2e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJP67020.1 - 5.4e-21 74.8 0.0 1.3e-16 60.6 0.0 2.3 1 1 1 2 2 2 2 Redoxin Glutaredoxin PF00462.24 EJP67020.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_8 PF13905.6 EJP67020.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.20 EJP67020.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin NAGLU PF05089.12 EJP67021.1 - 2.1e-131 437.9 8.7 3.4e-131 437.2 8.7 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 EJP67021.1 - 2.9e-75 253.2 10.1 5e-75 252.5 10.1 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 EJP67021.1 - 1e-20 73.3 0.0 3.7e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain VBS PF08913.10 EJP67021.1 - 0.21 12.1 0.2 0.53 10.7 0.2 1.6 1 0 0 1 1 1 0 Vinculin Binding Site Corona_S2 PF01601.16 EJP67022.1 - 3.9 5.9 22.0 5.4 5.4 22.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein STIMATE PF12400.8 EJP67023.1 - 7.7e-41 139.6 4.1 7.7e-41 139.6 4.1 1.6 2 0 0 2 2 2 1 STIMATE family Sod_Fe_C PF02777.18 EJP67024.1 - 2.6e-14 53.2 0.0 3.7e-12 46.3 0.0 2.3 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain PH PF00169.29 EJP67025.1 - 2.3e-05 24.8 0.0 7.4e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 EJP67025.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAT1 PF09770.9 EJP67025.1 - 0.23 9.7 23.7 0.45 8.7 23.7 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPL1 PF10513.9 EJP67025.1 - 0.58 10.5 11.6 0.087 13.2 7.2 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like Zip PF02535.22 EJP67025.1 - 0.96 8.6 3.3 1.6 7.9 3.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.8 EJP67025.1 - 2.3 8.3 11.5 1.4 9.0 5.4 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region GREB1 PF15782.5 EJP67025.1 - 4 4.4 11.4 5.8 3.9 11.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fungal_trans_2 PF11951.8 EJP67026.1 - 2.9e-80 269.9 0.0 3.8e-80 269.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67026.1 - 4.4e-08 33.1 4.9 7.5e-08 32.4 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM154 PF15102.6 EJP67027.1 - 1.2e-05 25.2 1.0 2.5e-05 24.2 1.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 EJP67027.1 - 0.00016 21.6 3.3 0.0002 21.2 2.4 1.6 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM51 PF15345.6 EJP67027.1 - 0.0026 17.7 0.1 0.0026 17.7 0.1 2.8 3 1 1 4 4 4 1 Transmembrane protein 51 RIFIN PF02009.16 EJP67027.1 - 0.0049 16.8 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 Rifin RCR PF12273.8 EJP67027.1 - 0.0098 16.5 10.6 0.062 14.0 9.5 2.5 1 1 1 2 2 2 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 EJP67027.1 - 0.012 16.4 0.0 0.012 16.4 0.0 2.8 4 0 0 4 4 3 0 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 EJP67027.1 - 0.015 14.9 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Syndecan PF01034.20 EJP67027.1 - 0.022 14.6 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain stn_TNFRSF12A PF12191.8 EJP67027.1 - 0.13 12.5 1.5 0.39 10.9 1.5 1.9 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SCF PF02404.15 EJP67027.1 - 0.19 11.0 0.3 0.32 10.3 0.3 1.2 1 0 0 1 1 1 0 Stem cell factor Adeno_E3_CR2 PF02439.15 EJP67027.1 - 0.72 9.7 3.7 1.4 8.8 3.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SPG4 PF17325.2 EJP67027.1 - 0.89 10.7 3.5 25 6.0 0.4 2.4 2 0 0 2 2 2 0 Stationary phase protein 4 Lustrin_cystein PF14625.6 EJP67027.1 - 3.3 8.2 17.4 7.6 7.0 1.6 2.9 2 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain TetR_C_11 PF16859.5 EJP67028.1 - 0.47 10.8 3.8 0.84 10.0 0.8 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Fungal_trans PF04082.18 EJP67029.1 - 1.3e-30 106.3 0.0 1.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1445 PF07286.12 EJP67030.1 - 5.1e-63 211.3 0.0 1.3e-62 210.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1445) Mon1 PF03164.14 EJP67033.1 - 8.4e-152 505.9 0.0 9.7e-152 505.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 AMP-binding PF00501.28 EJP67034.1 - 7.9e-73 245.5 0.0 1.2e-72 244.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EJP67034.1 - 1.4e-59 201.7 0.0 3.4e-59 200.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EJP67034.1 - 1.1e-25 89.9 0.0 2.4e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Condensation PF00668.20 EJP67034.1 - 6.4e-15 54.8 0.0 2.9e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.25 EJP67034.1 - 1.4e-08 34.9 0.0 5.5e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP67034.1 - 2e-06 28.7 0.0 6e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 EJP67034.1 - 0.002 17.5 1.1 0.003 17.0 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 EJP67034.1 - 0.0023 18.6 2.7 0.015 15.9 0.1 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJP67034.1 - 0.077 12.6 0.5 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EJP67034.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold KAsynt_C_assoc PF16197.5 EJP67034.1 - 0.13 12.7 0.0 0.45 11.0 0.0 2.0 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension MFS_1 PF07690.16 EJP67035.1 - 1.6e-50 172.0 45.0 8.1e-48 163.1 42.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytomega_TRL10 PF06084.11 EJP67035.1 - 9.8 6.2 6.5 34 4.4 0.1 2.8 3 0 0 3 3 3 0 Cytomegalovirus TRL10 protein Dopey_N PF04118.14 EJP67036.1 - 1.4e-116 389.0 0.0 3.6e-116 387.6 0.0 1.8 1 0 0 1 1 1 1 Dopey, N-terminal Sulfate_transp PF00916.20 EJP67036.1 - 0.037 12.8 0.1 0.069 11.9 0.1 1.3 1 0 0 1 1 1 0 Sulfate permease family bZIP_1 PF00170.21 EJP67037.1 - 0.0014 18.7 3.5 0.0025 17.9 3.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor HlyIII PF03006.20 EJP67038.1 - 3.6e-49 167.5 12.4 4.7e-49 167.1 12.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPW PF03779.14 EJP67038.1 - 0.19 11.3 0.0 0.19 11.3 0.0 2.8 3 0 0 3 3 3 0 SPW repeat DUF4187 PF13821.6 EJP67039.1 - 5.4e-22 77.3 1.5 1.2e-21 76.2 1.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EJP67039.1 - 1.7e-08 34.2 5.0 4.9e-08 32.7 5.0 1.9 1 1 0 1 1 1 1 G-patch domain DnaJ PF00226.31 EJP67040.1 - 1.1e-11 44.7 0.8 2.8e-10 40.2 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain Cofac_haem_bdg PF04187.13 EJP67040.1 - 0.034 14.1 0.6 0.07 13.1 0.1 1.7 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN SUIM_assoc PF16619.5 EJP67041.1 - 0.0037 17.3 3.6 0.0082 16.2 3.6 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 MARVEL PF01284.23 EJP67041.1 - 0.087 12.9 9.6 0.12 12.5 8.4 1.8 1 1 0 1 1 1 0 Membrane-associating domain Ninjurin PF04923.12 EJP67041.1 - 0.13 12.2 1.4 0.34 10.9 0.2 2.0 2 0 0 2 2 2 0 Ninjurin DUF4834 PF16118.5 EJP67041.1 - 0.37 11.8 3.0 39 5.3 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 EJP67041.1 - 0.49 10.3 9.4 0.83 9.6 9.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4064 PF13273.6 EJP67041.1 - 0.52 10.6 8.2 4.2 7.7 1.7 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DUF2569 PF10754.9 EJP67041.1 - 0.57 10.6 6.8 0.15 12.5 1.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2569) Spt20 PF12090.8 EJP67041.1 - 1.2 8.7 10.3 1.9 8.1 10.3 1.2 1 0 0 1 1 1 0 Spt20 family DEAD PF00270.29 EJP67042.1 - 3.2e-45 154.1 0.9 5.1e-45 153.4 0.9 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP67042.1 - 5.9e-32 110.3 0.2 8.8e-31 106.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP67042.1 - 1.8e-05 24.8 0.0 2.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EJP67042.1 - 0.00043 20.1 0.1 0.0008 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP67042.1 - 0.0077 16.6 1.3 0.036 14.4 0.4 2.2 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 EJP67042.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit IL17R_D_N PF16742.5 EJP67042.1 - 0.026 14.6 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D fragilysinNterm PF16376.5 EJP67042.1 - 0.034 13.9 0.1 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of fragilysin AAA_22 PF13401.6 EJP67042.1 - 0.075 13.3 0.5 0.34 11.2 0.5 2.1 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 EJP67042.1 - 0.14 12.2 0.2 0.59 10.1 0.2 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain DUF1771 PF08590.10 EJP67043.1 - 2.6e-15 56.5 11.6 6.5e-15 55.3 11.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 EJP67043.1 - 3.3e-08 33.3 7.9 1e-05 25.4 0.4 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EJP67043.1 - 2.9e-06 27.1 3.4 0.0011 18.8 0.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.21 EJP67043.1 - 3.3e-06 27.3 0.0 8.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 EJP67043.1 - 0.00024 21.4 4.5 0.11 13.0 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EJP67043.1 - 0.00037 20.2 11.1 0.0055 16.5 0.3 3.1 2 1 0 2 2 2 1 CCCH-type zinc finger HBS1_N PF08938.10 EJP67043.1 - 0.0057 16.9 0.1 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 HBS1 N-terminus CUE PF02845.16 EJP67043.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 CUE domain zf-CCCH_3 PF15663.5 EJP67043.1 - 0.085 13.1 2.6 5.9 7.2 0.1 2.3 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 EJP67043.1 - 0.27 12.0 5.0 5 7.9 4.9 2.2 1 1 0 1 1 1 0 Torus domain GGDEF_2 PF17853.1 EJP67044.1 - 0.027 14.7 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 GGDEF-like domain Transferase PF02458.15 EJP67045.1 - 0.00075 18.3 0.0 0.0087 14.7 0.0 2.0 2 0 0 2 2 2 2 Transferase family AATase PF07247.12 EJP67046.1 - 0.0088 14.6 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 EJP67046.1 - 0.087 11.5 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 Condensation domain ROQ_II PF18386.1 EJP67046.1 - 0.15 11.9 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Roquin II domain UDPGT PF00201.18 EJP67048.1 - 9.1e-07 28.0 0.0 1.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Pkinase PF00069.25 EJP67051.1 - 2.2e-26 92.8 0.0 2.3e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67051.1 - 6.8e-14 51.8 0.0 9.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP67051.1 - 4.5e-09 35.6 0.0 6.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EJP67051.1 - 0.00018 21.5 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Exo_endo_phos PF03372.23 EJP67052.1 - 0.001 18.6 0.0 0.0029 17.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 EJP67053.1 - 1.3e-57 195.2 0.0 1.6e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67053.1 - 2.7e-29 102.2 0.0 3.1e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP67053.1 - 0.00035 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJP67053.1 - 0.00045 20.2 0.3 0.019 14.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EJP67053.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EJP67053.1 - 0.037 12.8 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EJP67053.1 - 0.069 12.1 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RabGAP-TBC PF00566.18 EJP67054.1 - 5.8e-46 156.8 0.0 1.1e-45 155.9 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EJP67054.1 - 9.9e-05 22.0 0.5 0.014 15.3 0.3 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EJP67054.1 - 0.00077 19.9 0.1 1.1 9.8 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EJP67054.1 - 0.0012 18.2 1.7 0.074 12.6 0.6 3.5 3 0 0 3 3 3 1 EF hand GRAM PF02893.20 EJP67054.1 - 0.0066 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Caleosin PF05042.13 EJP67054.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Caleosin related protein ETX_MTX2 PF03318.13 EJP67055.1 - 0.0013 18.6 5.7 0.0019 18.0 5.7 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Fil_haemagg_2 PF13332.6 EJP67055.1 - 0.16 12.1 4.3 0.21 11.7 4.3 1.1 1 0 0 1 1 1 0 Hemagglutinin repeat Tudor-knot PF11717.8 EJP67056.1 - 0.083 12.8 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain TRI5 PF06330.11 EJP67058.1 - 5.6e-15 55.1 3.3 7.5e-15 54.7 3.3 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SRP1_TIP1 PF00660.17 EJP67058.1 - 0.0024 17.9 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Seripauperin and TIP1 family ACP53EA PF06313.11 EJP67058.1 - 0.1 12.8 1.5 0.14 12.4 0.1 1.9 2 0 0 2 2 2 0 Drosophila ACP53EA protein TPR_12 PF13424.6 EJP67059.1 - 3.9e-06 27.1 0.0 0.00068 19.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP67059.1 - 0.00011 22.6 0.1 0.34 11.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJP67059.1 - 0.0011 18.9 2.7 1.4 9.2 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EJP67059.1 - 0.0011 18.7 0.0 0.028 14.3 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP67059.1 - 0.0022 17.9 0.0 3.7 7.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Helo_like_N PF17111.5 EJP67059.1 - 0.0077 15.6 3.9 0.0077 15.6 3.9 2.4 3 0 0 3 3 3 1 Fungal N-terminal domain of STAND proteins TPR_1 PF00515.28 EJP67059.1 - 0.017 14.9 7.2 4.5 7.2 0.5 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJP67059.1 - 0.019 15.2 2.7 2 8.9 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP67059.1 - 0.031 15.1 0.0 10 7.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Cas1_AcylT PF07779.12 EJP67062.1 - 8.9e-118 394.2 15.9 2.8e-117 392.6 15.9 1.6 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Prenyltrans PF00432.21 EJP67062.1 - 0.12 12.2 1.4 0.9 9.3 0.0 2.9 2 1 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Ank_2 PF12796.7 EJP67063.1 - 9.8e-92 301.7 0.0 2e-15 57.1 0.0 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 EJP67063.1 - 1.5e-61 202.3 0.9 6.8e-05 23.1 0.0 11.3 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 EJP67063.1 - 1.1e-58 194.8 2.1 4.8e-08 33.4 0.0 8.0 3 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP67063.1 - 2.3e-57 190.3 8.5 1.7e-08 34.5 0.0 10.7 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP67063.1 - 1.8e-49 159.9 0.1 0.0029 18.0 0.0 12.1 12 0 0 12 12 12 10 Ankyrin repeat DUF3734 PF12536.8 EJP67063.1 - 0.00049 20.4 0.2 4.9 7.5 0.0 4.7 2 1 4 6 6 6 1 Patatin phospholipase PEGA PF08308.11 EJP67063.1 - 0.08 12.8 0.0 1.2e+02 2.6 0.0 4.7 6 0 0 6 6 6 0 PEGA domain GATase_7 PF13537.6 EJP67063.1 - 0.14 12.1 0.0 35 4.3 0.0 3.4 3 0 0 3 3 3 0 Glutamine amidotransferase domain VWA_3_C PF18571.1 EJP67063.1 - 0.32 10.9 8.8 14 5.6 0.0 6.0 9 0 0 9 9 9 0 von Willebrand factor type A C-terminal domain DUF4913 PF16259.5 EJP67063.1 - 0.55 10.3 3.0 11 6.1 0.1 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4913) MFS_1 PF07690.16 EJP67064.1 - 5.3e-46 157.2 45.6 9.7e-42 143.1 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EJP67064.1 - 0.018 13.3 0.3 0.018 13.3 0.3 3.9 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 EJP67065.1 - 2.5e-57 194.6 0.0 3.5e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.13 EJP67066.1 - 4.9e-27 95.0 0.0 6.9e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EJP67066.1 - 0.084 12.7 0.1 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EJP67066.1 - 0.15 12.7 13.4 0.43 11.1 13.4 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Arrestin_C PF02752.22 EJP67067.1 - 3e-16 60.1 0.0 1.3e-15 58.0 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EJP67067.1 - 1.4e-05 25.2 1.9 0.095 12.8 0.1 2.8 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain FAD_binding_3 PF01494.19 EJP67068.1 - 1.2e-19 70.8 0.5 2.8e-19 69.6 0.5 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EJP67068.1 - 0.00056 20.4 0.0 0.0026 18.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP67068.1 - 0.00085 19.0 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP67068.1 - 0.0014 17.9 0.1 0.42 9.8 0.0 2.5 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP67068.1 - 0.0027 17.9 0.0 0.0087 16.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EJP67068.1 - 0.0047 16.9 0.0 0.042 13.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Beta-lactamase PF00144.24 EJP67069.1 - 1.7e-51 175.4 1.0 2.5e-51 174.9 1.0 1.1 1 0 0 1 1 1 1 Beta-lactamase T7SS_ESX1_EccB PF05108.13 EJP67069.1 - 0.017 13.8 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B Peptidase_S11 PF00768.20 EJP67069.1 - 0.11 11.9 0.2 0.45 9.9 0.1 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Glyco_hydro_3 PF00933.21 EJP67070.1 - 8e-47 160.1 0.0 1e-46 159.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain NUDIX PF00293.28 EJP67071.1 - 8.7e-19 67.9 0.0 1.2e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EJP67071.1 - 0.0025 17.8 0.0 0.0044 17.0 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain WGG PF10273.9 EJP67072.1 - 2e-33 114.9 1.9 2.2e-33 114.8 0.7 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 EJP67072.1 - 0.025 14.7 0.1 0.067 13.3 0.1 1.7 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain TFIIF_alpha PF05793.12 EJP67072.1 - 1.1 7.7 11.8 1.5 7.4 11.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BSD PF03909.17 EJP67073.1 - 1.2e-20 73.2 0.1 2.7e-20 72.1 0.1 1.7 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.14 EJP67073.1 - 0.027 14.2 0.3 0.079 12.7 0.3 1.8 1 0 0 1 1 1 0 Sigma-70 region 2 Grg1 PF11034.8 EJP67075.1 - 2.9e-33 113.9 11.0 3.4e-33 113.7 11.0 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 RapA_C PF12137.8 EJP67075.1 - 0.13 11.2 1.4 0.13 11.2 1.4 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal PAP1 PF08601.10 EJP67076.1 - 1.1e-66 226.1 21.9 1.5e-48 166.4 0.0 4.6 1 1 2 4 4 4 2 Transcription factor PAP1 bZIP_1 PF00170.21 EJP67076.1 - 1.2e-07 31.7 12.4 2.6e-07 30.6 12.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor CCDC158 PF15921.5 EJP67076.1 - 0.0018 16.2 0.9 0.0026 15.7 0.9 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 158 SlyX PF04102.12 EJP67076.1 - 0.0022 18.5 1.9 0.0064 17.1 1.9 1.8 1 0 0 1 1 1 1 SlyX SHE3 PF17078.5 EJP67076.1 - 0.01 15.5 7.8 0.018 14.7 7.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Uso1_p115_C PF04871.13 EJP67076.1 - 0.033 14.6 9.4 0.089 13.2 9.4 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_2 PF07716.15 EJP67076.1 - 0.09 12.9 13.8 0.31 11.2 13.8 1.9 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 EJP67076.1 - 0.12 13.0 9.5 0.26 11.8 9.5 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor UPF0242 PF06785.11 EJP67076.1 - 1.5 8.9 6.1 2.9 8.0 6.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CDC45 PF02724.14 EJP67076.1 - 8.5 4.5 11.5 12 4.0 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 EJP67077.1 - 3.4e-59 200.4 0.0 4.4e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67077.1 - 5.2e-33 114.4 0.0 6.9e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP67077.1 - 0.00056 19.3 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EJP67077.1 - 0.015 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EJP67077.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP67077.1 - 0.029 14.3 2.3 0.032 14.2 0.2 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family adh_short_C2 PF13561.6 EJP67078.1 - 2.3e-52 177.9 0.6 2.7e-52 177.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP67078.1 - 2.6e-40 138.0 0.2 3.4e-40 137.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP67078.1 - 6.4e-07 29.5 0.2 1.2e-06 28.6 0.2 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EJP67078.1 - 6e-06 25.8 0.0 8.3e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EJP67078.1 - 0.037 13.5 0.1 0.055 12.9 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Calici_PP_N PF08405.11 EJP67078.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal 3HCDH_N PF02737.18 EJP67078.1 - 0.13 12.1 0.2 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 EJP67079.1 - 6.7e-24 84.7 13.1 1.6e-23 83.4 13.1 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJP67079.1 - 1.3e-07 32.2 0.1 6.1e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF3632 PF12311.8 EJP67080.1 - 2.4e-37 129.0 6.5 3.5e-37 128.5 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) zf-RING_2 PF13639.6 EJP67081.1 - 1.2e-07 32.0 6.1 1.7e-07 31.4 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EJP67081.1 - 1.2e-06 28.7 5.4 2.8e-06 27.5 5.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EJP67081.1 - 0.00022 21.2 3.6 0.00054 20.0 3.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EJP67081.1 - 0.0096 15.8 4.8 0.042 13.7 5.0 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EJP67081.1 - 0.014 15.5 0.7 0.014 15.5 0.7 1.7 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 EJP67081.1 - 0.025 14.4 1.5 0.12 12.2 0.5 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EJP67081.1 - 0.028 14.3 6.2 0.11 12.4 6.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP67081.1 - 0.23 11.4 4.3 0.42 10.5 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJP67081.1 - 0.43 10.4 7.0 0.076 12.8 2.4 2.0 2 0 0 2 2 2 0 RING-like zinc finger Epimerase PF01370.21 EJP67082.1 - 3e-10 40.0 0.0 5.9e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP67082.1 - 3.7e-10 40.0 0.1 6.1e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 EJP67082.1 - 7.9e-08 32.0 0.0 1.1e-06 28.3 0.0 2.0 1 1 1 2 2 2 1 HIM1 NmrA PF05368.13 EJP67082.1 - 2.8e-06 27.1 0.0 4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF1471 PF07338.13 EJP67082.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) K_oxygenase PF13434.6 EJP67082.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Semialdhyde_dh PF01118.24 EJP67082.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Flavokinase PF01687.17 EJP67083.1 - 1.2e-36 125.4 0.0 1.4e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.18 EJP67084.1 - 0.0059 16.7 8.8 0.0059 16.7 8.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EJP67084.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold zf-C2H2_2 PF12756.7 EJP67085.1 - 2.6e-24 85.5 2.2 6.3e-22 77.8 0.8 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EJP67085.1 - 0.17 12.2 0.5 0.17 12.2 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF2946 PF11162.8 EJP67085.1 - 0.18 12.4 13.6 0.22 12.2 1.7 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2946) zf-met PF12874.7 EJP67085.1 - 0.35 11.3 12.9 0.64 10.5 2.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Alpha_L_fucos PF01120.17 EJP67086.1 - 1.5e-82 277.9 3.6 2e-82 277.5 3.6 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase DUF3328 PF11807.8 EJP67087.1 - 9.3e-39 133.5 0.2 1.2e-38 133.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1059 PF06348.11 EJP67087.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) ABC_tran PF00005.27 EJP67088.1 - 4.2e-41 140.7 0.1 6e-20 72.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP67088.1 - 3.6e-30 105.6 43.8 1.2e-24 87.5 13.4 2.9 3 1 1 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP67088.1 - 9e-12 44.9 0.0 0.00026 20.5 1.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EJP67088.1 - 5.8e-05 22.3 0.1 0.019 14.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 EJP67088.1 - 7.9e-05 22.6 0.2 3.5 7.4 0.0 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP67088.1 - 0.0052 16.5 1.5 0.94 9.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJP67088.1 - 0.0056 16.7 0.0 0.33 11.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EJP67088.1 - 0.039 13.5 1.2 2 7.9 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EJP67088.1 - 0.041 13.2 0.2 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EJP67088.1 - 0.053 13.1 1.0 0.53 9.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EJP67088.1 - 0.069 13.5 0.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EJP67088.1 - 0.07 13.0 0.4 18 5.2 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EJP67088.1 - 0.086 12.2 1.0 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 EJP67088.1 - 0.16 10.8 6.8 2.6 6.9 0.1 3.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF2678 PF10856.8 EJP67088.1 - 0.6 10.1 4.2 0.66 9.9 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Pkinase PF00069.25 EJP67089.1 - 8.7e-25 87.6 0.0 1.9e-24 86.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67089.1 - 4.8e-19 68.6 0.0 7.7e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EJP67089.1 - 0.00027 20.9 0.1 0.00062 19.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP67089.1 - 0.00071 19.0 0.0 0.055 12.8 0.0 2.3 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 EJP67089.1 - 0.015 14.7 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EJP67089.1 - 0.038 13.6 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Amino_oxidase PF01593.24 EJP67090.1 - 1.4e-49 169.6 0.8 4.7e-49 167.9 0.8 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EJP67090.1 - 5.9e-15 55.7 0.9 1.1e-14 54.7 0.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP67090.1 - 1.1e-13 51.2 1.1 2.9e-13 49.9 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP67090.1 - 3.5e-08 33.0 0.1 4e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP67090.1 - 5.5e-08 31.9 0.2 8.8e-06 24.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EJP67090.1 - 2.9e-07 30.0 0.3 5.2e-07 29.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EJP67090.1 - 3.5e-06 26.3 0.1 0.0046 16.1 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 EJP67090.1 - 9.1e-06 25.3 0.2 1.5e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EJP67090.1 - 2.2e-05 23.9 0.1 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP67090.1 - 2.7e-05 23.5 0.1 8.8e-05 21.8 0.1 1.9 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EJP67090.1 - 7.5e-05 22.0 1.6 0.0002 20.6 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EJP67090.1 - 0.00016 22.2 0.1 0.0054 17.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP67090.1 - 0.00074 18.9 0.2 0.0014 18.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EJP67090.1 - 0.0022 18.0 1.6 0.58 10.1 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EJP67090.1 - 0.093 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NMO PF03060.15 EJP67091.1 - 5.4e-52 177.2 3.2 8.5e-52 176.6 3.2 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EJP67091.1 - 4.9e-09 35.6 2.7 2.4e-08 33.4 2.7 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EJP67091.1 - 0.023 13.8 2.7 0.039 13.0 2.7 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EJP67091.1 - 0.074 12.2 1.5 0.12 11.4 1.5 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase ABC_tran PF00005.27 EJP67092.1 - 2.3e-35 122.1 0.0 2e-17 64.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP67092.1 - 1.3e-16 61.1 15.7 1.3e-16 61.1 15.7 3.7 3 1 1 4 4 3 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 EJP67092.1 - 9.5e-06 25.7 0.1 0.059 13.5 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EJP67092.1 - 0.00025 21.5 0.3 1.7 9.1 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 EJP67092.1 - 0.00063 19.3 0.0 2.5 7.5 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP67092.1 - 0.00067 19.3 0.1 0.43 10.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ATPase_2 PF01637.18 EJP67092.1 - 0.0079 16.1 0.2 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EJP67092.1 - 0.0089 15.9 0.3 0.69 9.8 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EJP67092.1 - 0.024 14.9 0.2 15 5.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EJP67092.1 - 0.027 15.0 0.5 5 7.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EJP67092.1 - 0.044 13.6 3.7 3.8 7.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Methyltransf_25 PF13649.6 EJP67093.1 - 1.3e-13 51.5 0.2 1.5e-12 48.1 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP67093.1 - 2.3e-13 50.2 0.0 3.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67093.1 - 1.1e-12 48.5 0.1 6.1e-12 46.0 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP67093.1 - 1.2e-12 48.0 0.0 1.7e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJP67093.1 - 1.2e-10 41.2 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EJP67093.1 - 7.8e-07 29.8 0.0 1.7e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EJP67093.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.3 1 1 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EJP67093.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EJP67093.1 - 0.00013 22.0 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EJP67093.1 - 0.00015 21.0 0.0 0.0002 20.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 EJP67093.1 - 0.0019 17.6 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EJP67093.1 - 0.005 16.4 0.0 0.036 13.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 EJP67093.1 - 0.0052 16.9 0.0 0.0097 16.0 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EJP67093.1 - 0.038 13.3 0.0 0.087 12.1 0.0 1.5 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 EJP67093.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MFS_1 PF07690.16 EJP67095.1 - 1.9e-12 46.8 34.2 1.9e-12 46.8 34.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pam17 PF08566.10 EJP67095.1 - 0.73 9.7 2.4 18 5.1 0.8 2.4 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 MtN3_slv PF03083.16 EJP67095.1 - 1.5 8.9 8.3 7.8 6.6 0.5 3.3 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange MFS_1 PF07690.16 EJP67096.1 - 3.5e-45 154.5 27.2 1.8e-43 148.8 10.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EJP67096.1 - 6.2e-06 24.9 2.7 6.2e-06 24.9 2.7 2.9 2 1 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 EJP67096.1 - 0.0001 20.7 1.6 0.0001 20.7 1.6 2.3 3 1 1 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 EJP67096.1 - 0.0059 15.9 2.9 0.0059 15.9 2.9 2.8 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EJP67096.1 - 0.032 13.1 13.7 0.15 10.9 4.5 3.6 1 1 2 3 3 3 0 MFS_1 like family AMP-binding PF00501.28 EJP67097.1 - 4.2e-210 697.7 0.0 1.4e-78 264.4 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EJP67097.1 - 7.6e-126 420.4 0.0 4.4e-49 167.4 0.0 4.1 3 1 0 3 3 3 3 Condensation domain NAD_binding_4 PF07993.12 EJP67097.1 - 8.7e-34 116.8 0.0 1.4e-31 109.6 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EJP67097.1 - 1.9e-28 98.6 4.2 7.6e-09 35.8 0.1 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site Epimerase PF01370.21 EJP67097.1 - 9.7e-14 51.4 0.0 2.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EJP67097.1 - 1.9e-07 32.0 0.0 0.55 11.3 0.0 4.8 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 EJP67097.1 - 0.00087 18.5 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EJP67097.1 - 0.00093 18.3 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EJP67097.1 - 0.0019 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EJP67097.1 - 0.0048 16.3 0.0 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase HET PF06985.11 EJP67098.1 - 2.7e-24 86.2 0.0 6.7e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Formyl_trans_N PF00551.19 EJP67100.1 - 5.5e-38 130.5 0.1 6.8e-38 130.2 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EJP67100.1 - 1.7e-09 37.3 0.0 4.9e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EJP67100.1 - 0.00013 21.9 0.1 0.00069 19.5 0.0 2.2 2 0 0 2 2 2 1 ACT domain Sulfotransfer_4 PF17784.1 EJP67101.1 - 2.3e-51 174.7 0.0 2.8e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EJP67101.1 - 1.8e-05 25.2 0.9 0.0015 18.9 0.1 2.5 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EJP67101.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase domain Thymidylate_kin PF02223.17 EJP67102.1 - 8.3e-40 136.4 0.0 1.1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EJP67102.1 - 0.0073 16.6 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP67102.1 - 0.016 15.7 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 EJP67102.1 - 0.11 12.4 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 EJP67102.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ras PF00071.22 EJP67107.1 - 1.4e-31 109.2 0.2 1.8e-31 108.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP67107.1 - 4.6e-24 85.0 0.1 8.4e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP67107.1 - 1.8e-06 27.6 0.1 2.3e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJP67107.1 - 0.00046 19.6 0.1 0.00065 19.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EJP67107.1 - 0.03 13.2 3.4 0.38 9.5 0.0 2.4 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) NmrA PF05368.13 EJP67108.1 - 1.2e-17 64.3 0.0 1.6e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP67108.1 - 3.1e-10 40.3 0.0 6.5e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding 2OG-FeII_Oxy PF03171.20 EJP67109.1 - 1.2e-14 54.6 0.1 1.9e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EJP67109.1 - 2.4e-10 41.2 0.0 4.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CorA PF01544.18 EJP67110.1 - 9.9e-12 44.8 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Rop PF01815.16 EJP67110.1 - 0.026 14.4 0.9 0.065 13.1 0.9 1.7 1 0 0 1 1 1 0 Rop protein TPR_12 PF13424.6 EJP67111.1 - 2.1e-19 69.5 9.5 3.9e-08 33.5 0.1 3.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EJP67111.1 - 1.3e-10 40.8 2.5 0.048 13.5 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EJP67111.1 - 9.6e-08 31.6 8.9 0.16 12.1 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJP67111.1 - 2.9e-07 30.0 7.0 0.16 11.9 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 EJP67111.1 - 2.2e-06 27.0 0.0 4.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 EJP67111.1 - 9.7e-06 25.2 1.9 1.8e-05 24.3 1.9 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 EJP67111.1 - 0.0011 18.9 2.6 9.6 6.7 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EJP67111.1 - 0.0053 17.3 3.1 70 4.4 0.1 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 EJP67111.1 - 0.11 12.9 0.1 0.43 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain TPR_19 PF14559.6 EJP67111.1 - 0.12 12.9 5.3 0.27 11.8 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP67111.1 - 0.14 13.1 9.2 39 5.4 0.0 6.2 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EJP67111.1 - 8 7.2 0.0 8 7.2 0.0 5.0 5 1 0 6 6 4 0 Tetratricopeptide repeat GCV_H PF01597.19 EJP67112.1 - 2.3e-31 108.2 0.7 2.7e-31 108.0 0.7 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein TFX_C PF14601.6 EJP67112.1 - 0.073 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Porphobil_deam PF01379.20 EJP67113.1 - 1.3e-79 266.5 0.1 2.3e-79 265.7 0.0 1.4 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EJP67113.1 - 5.8e-18 65.0 0.2 1.2e-17 64.0 0.2 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF1180 PF06679.12 EJP67114.1 - 0.14 12.6 3.4 0.19 12.1 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PNTB PF02233.16 EJP67115.1 - 5.1e-172 572.9 26.2 5.1e-172 572.9 26.2 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EJP67115.1 - 1e-74 250.4 0.4 4.4e-74 248.4 0.4 2.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EJP67115.1 - 2.8e-48 163.7 0.8 1.5e-47 161.3 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EJP67115.1 - 5.8e-30 103.6 3.1 5.8e-30 103.6 3.1 5.6 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EJP67115.1 - 0.0017 17.8 0.1 0.37 10.1 0.1 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EJP67115.1 - 0.015 14.5 0.1 0.042 13.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 EJP67115.1 - 0.016 15.2 0.2 0.061 13.3 0.2 2.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GIDA PF01134.22 EJP67115.1 - 0.082 12.0 0.8 0.14 11.2 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Cytochrom_B561 PF03188.16 EJP67115.1 - 0.37 10.9 4.7 0.31 11.2 1.6 2.6 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 NAD_binding_8 PF13450.6 EJP67115.1 - 0.65 10.3 4.2 0.22 11.8 0.3 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NDUFA12 PF05071.16 EJP67116.1 - 6.2e-27 94.3 0.5 7.4e-27 94.0 0.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 EJP67117.1 - 5.6e-12 45.7 0.0 0.00011 22.2 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EJP67117.1 - 1.8e-07 31.1 3.6 0.0079 16.3 0.2 3.5 3 1 0 3 3 3 2 Phospholipase D Active site motif Ribosomal_L4 PF00573.22 EJP67118.1 - 2.3e-44 151.4 0.0 3.4e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family HTH_42 PF06224.12 EJP67118.1 - 0.026 14.1 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain PBP PF01161.20 EJP67119.1 - 4.7e-08 33.4 0.0 8.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein bZIP_1 PF00170.21 EJP67120.1 - 2.7e-12 46.6 9.0 4.5e-12 45.9 9.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EJP67120.1 - 0.00018 21.5 14.7 0.00018 21.5 14.7 2.6 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EJP67120.1 - 0.00065 20.2 7.3 0.00065 20.2 7.3 2.5 3 0 0 3 3 3 1 bZIP Maf transcription factor Prominin PF05478.11 EJP67120.1 - 0.0058 14.7 0.6 0.0074 14.3 0.6 1.1 1 0 0 1 1 1 1 Prominin Sporozoite_P67 PF05642.11 EJP67120.1 - 0.076 11.1 8.7 0.16 10.1 8.7 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATF7IP_BD PF16788.5 EJP67120.1 - 0.51 10.4 10.9 0.37 10.9 0.5 2.3 2 0 0 2 2 2 0 ATF-interacting protein binding domain ASD2 PF08687.11 EJP67120.1 - 1.1 8.8 10.1 1.7 8.1 10.1 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 ANAPC1 PF12859.7 EJP67120.1 - 1.1 9.8 7.8 0.66 10.5 3.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 PRP38_assoc PF12871.7 EJP67120.1 - 6.5 7.4 19.7 3.3 8.4 17.1 1.9 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Rep_fac-A_3 PF08661.11 EJP67121.1 - 5.8e-18 65.2 0.0 6.2e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 FAM176 PF14851.6 EJP67122.1 - 0.1 12.2 2.7 0.14 11.8 2.7 1.2 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 EJP67122.1 - 0.24 9.4 3.7 0.083 11.0 1.5 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NOA36 PF06524.12 EJP67122.1 - 0.26 10.6 17.7 0.33 10.2 17.7 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EJP67122.1 - 0.33 11.0 6.3 0.46 10.5 6.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Osteopontin PF00865.18 EJP67122.1 - 0.36 10.3 15.7 0.39 10.2 15.7 1.2 1 0 0 1 1 1 0 Osteopontin DUF2076 PF09849.9 EJP67122.1 - 0.38 10.7 5.0 0.46 10.5 5.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CDC45 PF02724.14 EJP67122.1 - 0.45 8.7 6.3 0.51 8.6 6.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Med13_C PF06333.12 EJP67122.1 - 0.48 9.6 2.6 0.55 9.4 2.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF2457 PF10446.9 EJP67122.1 - 0.54 9.4 19.4 0.69 9.0 19.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 EJP67122.1 - 1.1 8.7 6.3 1.4 8.3 6.3 1.2 1 0 0 1 1 1 0 SDA1 GCIP PF13324.6 EJP67122.1 - 2.1 7.9 6.1 3.4 7.2 6.1 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 EJP67122.1 - 3.7 8.0 21.6 0.39 11.1 17.3 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EJP67122.1 - 4 7.1 15.6 5.8 6.6 15.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EJP67122.1 - 4.4 5.4 8.8 5.2 5.2 8.8 1.0 1 0 0 1 1 1 0 Nop14-like family RhoGAP PF00620.27 EJP67123.1 - 2.7e-12 46.8 0.0 9.2e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain CBS PF00571.28 EJP67124.1 - 2e-25 89.0 5.5 6.4e-11 42.5 0.2 4.3 4 0 0 4 4 4 4 CBS domain Arm PF00514.23 EJP67125.1 - 4.5e-75 245.6 36.5 4.1e-13 48.9 0.2 11.1 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EJP67125.1 - 3.6e-17 62.5 10.3 0.00013 22.4 0.3 7.5 6 1 1 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 EJP67125.1 - 3.9e-17 62.4 10.1 5.6e-05 23.5 0.2 6.6 2 2 3 7 7 7 5 HEAT repeats HEAT PF02985.22 EJP67125.1 - 9.5e-15 53.5 14.7 0.09 13.1 0.5 8.7 9 0 0 9 9 9 5 HEAT repeat Adaptin_N PF01602.20 EJP67125.1 - 4.9e-11 41.9 8.9 1.9e-06 26.8 0.4 2.6 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 EJP67125.1 - 2.8e-10 40.1 8.3 5.7e-08 32.5 2.8 3.2 1 1 3 4 4 4 3 Armadillo-like KAP PF05804.12 EJP67125.1 - 1.8e-09 36.3 0.1 4.4e-09 35.1 0.1 1.4 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EJP67125.1 - 4.9e-08 32.6 1.5 0.00011 21.6 1.2 2.9 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 EJP67125.1 - 4e-05 23.7 1.3 15 5.7 0.1 4.9 2 1 5 7 7 7 0 V-ATPase subunit H DUF3361 PF11841.8 EJP67125.1 - 0.00025 21.0 9.1 0.36 10.7 0.2 4.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3361) Cnd1 PF12717.7 EJP67125.1 - 0.0005 20.2 8.4 0.71 9.9 0.4 4.6 1 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EJP67125.1 - 0.0011 18.2 4.8 0.51 9.4 0.3 3.9 2 2 1 3 3 3 2 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 EJP67125.1 - 0.016 15.2 1.2 2 8.3 0.2 3.4 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central HEAT_PBS PF03130.16 EJP67125.1 - 0.042 14.5 10.3 31 5.7 0.3 7.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 EJP67125.1 - 0.081 13.5 0.3 4.5 7.9 0.0 3.2 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Sigma70_r1_1 PF03979.14 EJP67125.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Atx10homo_assoc PF09759.9 EJP67125.1 - 0.71 9.9 7.3 5.5 7.1 0.1 4.1 3 2 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Peptidase_S26 PF10502.9 EJP67126.1 - 0.00012 21.8 0.0 0.0094 15.7 0.0 2.4 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 EJP67126.1 - 0.00027 20.8 0.1 0.00081 19.3 0.1 1.7 2 0 0 2 2 2 1 Peptidase S24-like IF3_C PF00707.22 EJP67127.1 - 4.7e-12 45.7 0.2 7.8e-12 45.0 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 EJP67127.1 - 3.3e-06 26.9 2.2 5.8e-06 26.1 2.2 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Jnk-SapK_ap_N PF09744.9 EJP67127.1 - 0.33 11.2 7.8 0.31 11.2 6.8 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Alb1 PF09135.11 EJP67128.1 - 4.3e-28 98.3 14.7 4.3e-28 98.3 14.7 2.0 2 0 0 2 2 2 1 Alb1 Amidase PF01425.21 EJP67129.1 - 2.1e-10 40.2 1.8 5.5e-10 38.8 0.6 2.1 2 1 0 2 2 2 1 Amidase He_PIG PF05345.12 EJP67129.1 - 0.076 13.2 0.4 5.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Putative Ig domain DUF1965 PF09248.10 EJP67129.1 - 0.093 12.5 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Acetyltransf_10 PF13673.7 EJP67130.1 - 0.00024 21.0 0.0 0.0006 19.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP67130.1 - 0.0014 18.5 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EJP67130.1 - 0.0034 17.6 0.0 0.005 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 EJP67130.1 - 0.006 16.2 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_7 PF13508.7 EJP67130.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP67130.1 - 0.11 12.5 0.1 0.35 11.0 0.1 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Trypsin PF00089.26 EJP67131.1 - 6.4e-36 124.2 2.1 7.5e-22 78.2 0.3 2.1 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.6 EJP67131.1 - 0.0026 18.6 1.2 0.016 16.1 1.2 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C107 PF17222.3 EJP67131.1 - 0.13 11.2 0.3 14 4.5 0.0 2.7 2 1 1 3 3 3 0 Viral cysteine endopeptidase C107 Enterotoxin_a PF01375.17 EJP67132.1 - 3.7e-10 39.8 0.0 6.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain Ank_2 PF12796.7 EJP67133.1 - 3.2e-10 40.4 0.2 6.9e-09 36.2 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP67133.1 - 8.4e-06 25.8 0.2 0.15 12.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EJP67133.1 - 4.2e-05 23.7 0.6 0.028 14.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EJP67133.1 - 7.2e-05 23.3 0.3 0.017 15.7 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EJP67133.1 - 0.0011 19.3 0.5 0.093 13.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat DUF848 PF05852.11 EJP67133.1 - 0.04 14.0 0.5 0.67 10.1 0.0 2.6 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Poxvirus_B22R PF04395.12 EJP67133.1 - 0.21 11.1 1.9 0.44 10.1 1.9 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein Pox_A28 PF04584.14 EJP67134.1 - 0.0018 18.5 0.6 1.1 9.4 0.2 2.3 2 0 0 2 2 2 2 Poxvirus A28 family Dimer_Tnp_hAT PF05699.14 EJP67135.1 - 2.3e-17 62.6 0.2 3.8e-17 61.8 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Fungal_trans PF04082.18 EJP67136.1 - 9.3e-13 47.8 0.1 1.8e-12 46.9 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67136.1 - 1.9e-08 34.3 11.6 3.5e-08 33.4 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4995 PF16386.5 EJP67136.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Polyketide_cyc2 PF10604.9 EJP67137.1 - 1.3e-13 51.4 0.0 1.6e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ribonuc_L-PSP PF01042.21 EJP67139.1 - 8.2e-20 71.0 0.0 9.9e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ricin_B_lectin PF00652.22 EJP67140.1 - 8.1e-12 45.5 4.1 0.00058 20.1 0.0 4.8 3 3 2 5 5 5 4 Ricin-type beta-trefoil lectin domain MaoC_dehydratas PF01575.19 EJP67141.1 - 2.9e-08 33.3 0.1 8.2e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain Glyco_transf_34 PF05637.12 EJP67142.1 - 1.5e-09 37.9 0.4 4.3e-09 36.4 0.4 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 EJP67142.1 - 0.0017 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Pectate_lyase_3 PF12708.7 EJP67143.1 - 7.7e-42 143.6 2.8 4.6e-32 111.6 0.3 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein GMC_oxred_C PF05199.13 EJP67144.1 - 2.7e-09 37.7 0.0 2.5e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EJP67144.1 - 0.00022 20.5 0.4 0.00044 19.4 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EJP67144.1 - 0.001 19.3 0.3 0.011 15.9 0.6 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EJP67144.1 - 0.0078 15.6 0.5 0.013 14.9 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP67144.1 - 0.021 14.1 0.2 0.045 13.0 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP67144.1 - 0.071 12.2 0.2 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Alk_phosphatase PF00245.20 EJP67147.1 - 4.5e-102 342.1 0.1 5.7e-102 341.8 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EJP67147.1 - 1.7e-05 24.4 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily HEAT PF02985.22 EJP67147.1 - 0.017 15.4 1.4 0.35 11.3 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat Sulfatase PF00884.23 EJP67147.1 - 0.045 13.1 0.9 2.5 7.4 0.5 2.8 2 1 0 2 2 2 0 Sulfatase Hydrolase_4 PF12146.8 EJP67148.1 - 2.7e-13 49.7 0.0 9.4e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP67148.1 - 3.7e-12 46.4 0.1 6.4e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.20 EJP67148.1 - 4.6e-10 39.4 0.0 9.9e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_6 PF12697.7 EJP67148.1 - 9.8e-10 39.4 4.9 9.8e-10 39.4 4.9 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family PTPlike_phytase PF14566.6 EJP67148.1 - 2.6e-05 24.4 0.0 4.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Thioesterase PF00975.20 EJP67148.1 - 5.6e-05 23.4 0.0 0.00013 22.2 0.0 1.6 2 0 0 2 2 1 1 Thioesterase domain LIDHydrolase PF10230.9 EJP67148.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EJP67148.1 - 0.0002 21.2 0.1 0.00068 19.4 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 EJP67148.1 - 0.0053 16.0 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Y_phosphatase PF00102.27 EJP67148.1 - 0.0062 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Lipase_3 PF01764.25 EJP67148.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 EJP67148.1 - 0.019 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EJP67148.1 - 0.023 14.3 0.1 0.057 13.1 0.0 1.6 2 0 0 2 2 2 0 Putative esterase DUF900 PF05990.12 EJP67148.1 - 0.032 13.8 0.0 0.075 12.5 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2275 PF10039.9 EJP67148.1 - 0.06 13.4 0.1 1.3 9.1 0.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) DUF1749 PF08538.10 EJP67148.1 - 0.2 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF498 PF04430.14 EJP67149.1 - 6.5e-28 97.0 0.0 1e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Ribosomal_L34e PF01199.18 EJP67150.1 - 8e-43 144.7 2.9 1.1e-42 144.3 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 EJP67150.1 - 0.17 11.9 3.4 1.7 8.7 0.3 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Zn_ribbon_recom PF13408.6 EJP67150.1 - 3.2 8.3 7.4 0.77 10.3 3.2 2.1 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Phage_sheath_1 PF04984.14 EJP67151.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain FAR1 PF03101.15 EJP67152.1 - 7.9e-06 26.5 0.1 1.2e-05 25.9 0.1 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain Sugarporin_N PF11471.8 EJP67152.1 - 0.00017 21.5 0.7 0.00048 20.0 0.2 1.9 1 1 1 2 2 2 1 Maltoporin periplasmic N-terminal extension XhlA PF10779.9 EJP67152.1 - 0.00037 20.6 0.0 0.0008 19.6 0.0 1.5 1 1 0 1 1 1 1 Haemolysin XhlA AFT PF08731.11 EJP67152.1 - 0.0092 16.4 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor AFT Zn_clus PF00172.18 EJP67153.1 - 8.5e-07 29.0 13.0 1.6e-06 28.1 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EJP67154.1 - 8.1e-06 25.6 2.4 0.00053 19.8 0.1 3.2 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 EJP67154.1 - 4.4e-05 23.3 1.4 4.4e-05 23.3 1.4 2.5 2 0 0 2 2 2 1 F-box domain FA_hydroxylase PF04116.13 EJP67155.1 - 4e-08 33.7 9.5 1.2e-07 32.1 9.3 1.9 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily RmlD_sub_bind PF04321.17 EJP67155.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TMEM189_B_dmain PF10520.9 EJP67155.1 - 0.51 10.4 5.0 1.5 8.9 0.3 2.2 1 1 1 2 2 2 0 B domain of TMEM189, localisation domain Rad9 PF04139.13 EJP67156.1 - 1.3e-40 139.4 0.0 1.6e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.18 EJP67157.1 - 3.6e-29 101.1 13.6 4.9e-09 36.7 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EJP67157.1 - 2.1e-10 40.1 28.0 0.0008 19.1 0.5 5.6 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PDH PF02153.17 EJP67158.1 - 8.6e-15 54.4 0.0 1.2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 EJP67158.1 - 8.8e-07 29.4 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EJP67158.1 - 2.3e-06 27.9 0.0 3.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EJP67158.1 - 0.00036 20.0 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EJP67158.1 - 0.0053 16.4 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EJP67158.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EJP67158.1 - 0.083 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mpv17_PMP22 PF04117.12 EJP67160.1 - 8.1e-11 42.0 6.1 1.6e-10 41.0 4.6 2.0 1 1 1 2 2 2 1 Mpv17 / PMP22 family NADH_oxidored PF08040.11 EJP67160.1 - 0.018 14.7 0.2 0.089 12.5 0.1 2.2 2 1 0 2 2 2 0 MNLL subunit SelK_SelG PF10961.8 EJP67160.1 - 0.27 11.9 0.2 0.27 11.9 0.2 2.2 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Serinc PF03348.15 EJP67160.1 - 0.31 9.9 3.8 0.45 9.4 3.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) EAP30 PF04157.16 EJP67161.1 - 9.9e-73 244.3 0.1 1.1e-72 244.1 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DnaJ_C PF01556.18 EJP67162.1 - 9.6e-34 116.6 0.0 1.5e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJP67162.1 - 4.6e-24 84.3 4.5 7.7e-24 83.6 4.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EJP67162.1 - 1.5e-13 50.9 17.5 3.1e-13 49.9 17.5 1.6 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 EJP67162.1 - 0.0035 17.3 5.2 0.019 15.0 0.5 2.3 2 0 0 2 2 2 1 Cytochrome c7 and related cytochrome c Anti-TRAP PF15777.5 EJP67162.1 - 0.015 15.3 12.2 0.21 11.6 1.2 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Malate_DH PF12434.8 EJP67162.1 - 0.13 12.3 0.1 0.45 10.6 0.1 1.9 1 0 0 1 1 1 0 Malate dehydrogenase enzyme HypA PF01155.19 EJP67162.1 - 0.92 9.6 6.0 7.8 6.6 0.9 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 EJP67162.1 - 6.5 7.3 8.7 8.6 6.9 2.8 2.2 1 1 1 2 2 2 0 Cytochrome c3 AMP-binding PF00501.28 EJP67163.1 - 3.3e-45 154.4 0.0 5e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP67163.1 - 9.5e-06 26.5 0.2 9.5e-06 26.5 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EJP67163.1 - 0.0088 15.9 0.9 0.044 13.7 0.1 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus WD40 PF00400.32 EJP67164.1 - 1.6e-36 123.7 20.2 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP67164.1 - 1.8e-14 53.8 0.1 0.00035 20.8 0.1 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP67164.1 - 6.7e-05 22.0 0.1 0.8 8.6 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EJP67164.1 - 0.00039 20.4 0.0 0.21 11.5 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EJP67164.1 - 0.0073 15.7 0.0 0.92 8.8 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain ADIP PF11559.8 EJP67164.1 - 0.28 11.3 3.4 0.4 10.8 3.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GrpE PF01025.19 EJP67164.1 - 0.28 10.8 1.4 0.44 10.2 1.4 1.2 1 0 0 1 1 1 0 GrpE Phosducin PF02114.16 EJP67166.1 - 3.3e-08 32.8 0.0 4.3e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 Phosducin DUF2847 PF11009.8 EJP67166.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) KOW PF00467.29 EJP67166.1 - 5.5 7.1 4.8 43 4.2 0.1 3.2 3 0 0 3 3 3 0 KOW motif REC114-like PF15165.6 EJP67167.1 - 0.063 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Ran_BP1 PF00638.18 EJP67168.1 - 7.8e-50 168.2 1.1 1.3e-49 167.5 1.1 1.3 1 0 0 1 1 1 1 RanBP1 domain CDC27 PF09507.10 EJP67168.1 - 0.0033 16.9 19.3 0.0052 16.2 19.3 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 VID27_PH PF17747.1 EJP67168.1 - 0.015 15.6 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 VID27 PH-like domain YEATS PF03366.16 EJP67169.1 - 1.5e-19 69.7 0.0 3e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EJP67169.1 - 0.00013 22.1 2.6 0.0014 18.7 2.6 2.4 1 1 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Zn_clus PF00172.18 EJP67170.1 - 3.3e-07 30.3 11.9 5.5e-07 29.6 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PP2C PF00481.21 EJP67172.1 - 4e-63 213.4 0.4 1.1e-50 172.6 0.0 2.9 2 1 0 2 2 2 2 Protein phosphatase 2C Terminase_4 PF05119.12 EJP67172.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Phage terminase, small subunit APH PF01636.23 EJP67173.1 - 8.9e-15 55.3 0.0 2.7e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP67173.1 - 0.00044 19.9 0.1 0.00081 19.0 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Snf7 PF03357.21 EJP67175.1 - 3.2e-36 124.5 19.1 4.9e-36 123.9 19.1 1.2 1 0 0 1 1 1 1 Snf7 CaMBD PF02888.16 EJP67175.1 - 0.075 13.2 0.8 0.075 13.2 0.8 2.2 3 0 0 3 3 3 0 Calmodulin binding domain Ist1 PF03398.14 EJP67175.1 - 0.2 11.6 6.3 0.32 10.9 6.3 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PspA_IM30 PF04012.12 EJP67175.1 - 1.8 8.1 15.8 3.1 7.3 5.1 2.2 1 1 1 2 2 2 0 PspA/IM30 family Dynamin_N PF00350.23 EJP67176.1 - 3.7e-18 66.1 1.6 4.7e-18 65.8 0.1 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EJP67176.1 - 5.7e-10 39.3 0.0 4.5e-09 36.4 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJP67176.1 - 3e-05 23.7 1.5 0.00047 19.8 1.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PMEI PF04043.15 EJP67176.1 - 0.0022 18.4 0.2 0.0079 16.6 0.2 1.9 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Lipase_GDSL_3 PF14606.6 EJP67176.1 - 0.038 14.1 1.3 21 5.2 0.1 3.6 4 0 0 4 4 4 0 GDSL-like Lipase/Acylhydrolase family IIGP PF05049.13 EJP67176.1 - 0.041 12.9 0.2 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) HicB_lk_antitox PF15919.5 EJP67176.1 - 0.056 13.6 0.0 0.26 11.4 0.0 2.1 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Sigma54_activat PF00158.26 EJP67176.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 EJP67176.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EJP67176.1 - 0.082 13.5 0.4 0.44 11.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 EJP67176.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EJP67176.1 - 0.14 12.4 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FH2 PF02181.23 EJP67176.1 - 0.16 11.1 1.3 0.24 10.5 0.2 1.7 2 0 0 2 2 2 0 Formin Homology 2 Domain End3 PF12761.7 EJP67176.1 - 1.1 9.4 10.1 0.85 9.8 0.5 3.9 3 1 1 4 4 4 0 Actin cytoskeleton-regulatory complex protein END3 A_deaminase PF00962.22 EJP67177.1 - 1.1e-23 84.1 0.0 1.5e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_2 PF04909.14 EJP67177.1 - 0.12 12.2 1.1 0.23 11.2 1.1 1.6 1 1 0 1 1 1 0 Amidohydrolase Tom22 PF04281.13 EJP67178.1 - 4.6e-48 162.5 0.1 5.7e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 YL1 PF05764.13 EJP67178.1 - 7.5 6.6 6.4 12 5.9 6.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein ELFV_dehydrog PF00208.21 EJP67179.1 - 1.1e-62 211.9 0.0 1.7e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EJP67179.1 - 7.3e-18 63.6 0.0 4e-13 47.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EJP67179.1 - 0.003 17.4 0.0 0.0095 15.8 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SH3_1 PF00018.28 EJP67180.1 - 3.6e-05 23.3 0.0 7.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP67180.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Ribosomal_L32e PF01655.18 EJP67181.1 - 7.5e-51 171.1 0.3 7.5e-51 171.1 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L32 Ribosomal_S9 PF00380.19 EJP67182.1 - 1e-33 116.4 0.4 1.2e-33 116.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.9 EJP67182.1 - 0.18 9.7 0.0 0.21 9.5 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein AAR2 PF05282.11 EJP67183.1 - 1.4e-45 156.3 0.0 1.8e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein zf-C2H2 PF00096.26 EJP67184.1 - 0.21 12.1 0.2 0.41 11.2 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DEAD PF00270.29 EJP67186.1 - 1.4e-49 168.2 0.0 3.1e-48 163.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP67186.1 - 2.5e-31 108.3 0.2 8.3e-31 106.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP67186.1 - 7.6e-06 26.0 0.0 3.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EJP67186.1 - 0.0047 15.8 0.1 0.48 9.1 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 EJP67186.1 - 0.0093 15.2 0.3 0.014 14.6 0.3 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 EJP67186.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_19 PF13245.6 EJP67186.1 - 0.035 14.4 0.0 13 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2443 PF10398.9 EJP67186.1 - 0.089 12.9 0.2 0.2 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF5335 PF17269.2 EJP67186.1 - 0.095 12.5 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Pyr_redox_2 PF07992.14 EJP67187.1 - 1.8e-53 181.7 0.4 2.3e-53 181.4 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP67187.1 - 1.9e-12 47.6 0.0 4.7e-11 43.1 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP67187.1 - 0.00032 20.0 0.5 0.14 11.4 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TetR_C_19 PF17924.1 EJP67187.1 - 0.078 13.6 0.0 0.41 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain APH PF01636.23 EJP67188.1 - 5.4e-12 46.1 0.1 4.2e-11 43.2 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP67188.1 - 0.00019 21.1 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EJP67188.1 - 0.014 14.7 0.0 0.034 13.3 0.0 1.6 2 0 0 2 2 2 0 Fructosamine kinase Kdo PF06293.14 EJP67188.1 - 0.029 13.7 0.0 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 EJP67188.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) TENA_THI-4 PF03070.16 EJP67190.1 - 9e-52 175.9 0.0 1.3e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Phos_pyr_kin PF08543.12 EJP67190.1 - 1.9e-36 125.7 0.0 3e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EJP67190.1 - 8.1e-05 22.1 0.4 0.0026 17.1 0.4 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 EJP67190.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EJP67191.1 - 1.1e-34 119.9 4.0 1.2e-34 119.8 4.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase RICTOR_N PF14664.6 EJP67192.1 - 8.8e-131 436.3 0.1 8.8e-131 436.3 0.1 1.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EJP67192.1 - 1.4e-37 127.6 0.2 6.5e-35 119.1 0.0 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EJP67192.1 - 2.5e-36 124.3 0.5 3.9e-34 117.3 0.0 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EJP67192.1 - 2.2e-28 98.3 0.3 4.8e-27 94.0 0.1 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EJP67192.1 - 1.8e-12 47.2 10.8 1.8e-12 47.2 10.8 2.6 2 0 0 2 2 2 1 Hr1 repeat Golgin_A5 PF09787.9 EJP67192.1 - 0.00012 21.6 6.5 0.00012 21.6 6.5 2.2 2 0 0 2 2 2 1 Golgin subfamily A member 5 SspB PF04386.13 EJP67192.1 - 0.28 11.1 5.9 0.79 9.6 5.9 1.7 1 0 0 1 1 1 0 Stringent starvation protein B UPF0239 PF06783.11 EJP67192.1 - 5.8 7.2 5.7 16 5.7 5.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) CDC45 PF02724.14 EJP67192.1 - 9 4.5 17.2 40 2.3 0.0 2.4 2 0 0 2 2 2 0 CDC45-like protein Uricase PF01014.18 EJP67193.1 - 7.2e-77 256.0 2.0 1.1e-39 135.7 1.0 2.0 2 0 0 2 2 2 2 Uricase DUF2139 PF09910.9 EJP67193.1 - 0.075 12.2 0.4 7.5 5.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2139) Ribosomal_L13 PF00572.18 EJP67194.1 - 2.5e-40 137.6 0.2 5.7e-40 136.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 Pkinase PF00069.25 EJP67195.1 - 9.3e-39 133.4 0.0 1.5e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67195.1 - 1.8e-23 83.2 0.0 2.9e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP67195.1 - 0.00011 21.1 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EJP67195.1 - 0.0029 17.0 0.0 0.17 11.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like FHA PF00498.26 EJP67195.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 FHA domain HMA PF00403.26 EJP67197.1 - 4.8e-11 42.9 0.0 7.6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EJP67197.1 - 1.3e-08 35.2 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPR_1 PF00515.28 EJP67198.1 - 4.7e-18 64.2 4.4 1.6e-08 34.0 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP67198.1 - 1.1e-15 56.4 4.4 1.8e-06 27.6 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EJP67198.1 - 6.8e-11 41.5 2.4 6.4e-06 26.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EJP67198.1 - 4.8e-09 36.3 0.1 0.079 13.6 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EJP67198.1 - 2.6e-08 33.3 0.5 3.5e-06 26.7 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP67198.1 - 6.2e-08 32.8 1.4 2e-07 31.2 0.1 2.5 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJP67198.1 - 5.5e-07 29.2 1.7 1.1e-05 25.0 0.1 3.4 2 1 1 3 3 3 1 TPR repeat PB1 PF00564.24 EJP67198.1 - 7.2e-06 25.9 0.1 1.3e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.6 EJP67198.1 - 0.0001 22.4 0.3 0.14 12.3 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJP67198.1 - 0.00011 22.8 0.2 0.0068 17.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EJP67198.1 - 0.00015 21.9 0.1 0.25 11.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EJP67198.1 - 0.0013 18.5 1.7 0.16 11.9 0.0 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EJP67198.1 - 0.0068 17.1 0.1 0.2 12.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EJP67198.1 - 0.089 13.5 0.0 43 5.2 0.0 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.21 EJP67199.1 - 3.7e-83 279.0 0.0 4.6e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Aminotran_1_2 PF00155.21 EJP67202.1 - 2.6e-56 191.4 0.0 3.5e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EJP67202.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EJP67202.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase SAM_2 PF07647.17 EJP67203.1 - 1.5e-15 57.1 0.0 2.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EJP67203.1 - 4.3e-15 55.9 0.0 1.1e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EJP67203.1 - 3.1e-11 43.8 0.0 5.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 EJP67203.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Glu-tRNAGln PF02686.15 EJP67203.1 - 0.087 13.1 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Pkinase PF00069.25 EJP67204.1 - 2e-22 79.8 0.0 8.3e-22 77.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67204.1 - 1.1e-06 28.1 0.0 2.5e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 EJP67206.1 - 0.00068 19.5 0.1 0.0016 18.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like Afi1 PF07792.12 EJP67206.1 - 0.38 11.2 3.8 0.62 10.6 1.4 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AAT PF03417.16 EJP67207.1 - 1.5e-16 60.8 0.0 2.1e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Abhydrolase_1 PF00561.20 EJP67208.1 - 1.7e-18 67.2 0.0 1.9e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP67208.1 - 6.6e-11 43.2 0.9 8.7e-11 42.8 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP67208.1 - 2.2e-06 27.1 0.0 2.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Iso_dh PF00180.20 EJP67209.1 - 5.1e-85 285.7 0.0 6.2e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_1 PF00561.20 EJP67210.1 - 3.8e-16 59.5 0.0 5.6e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP67210.1 - 3.3e-12 47.5 0.0 3.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP67210.1 - 5.5e-09 35.6 0.0 7.4e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thr_synth_N PF14821.6 EJP67210.1 - 0.0089 16.2 0.0 0.032 14.4 0.0 1.9 2 0 0 2 2 2 1 Threonine synthase N terminus Ndr PF03096.14 EJP67210.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Fungal_trans PF04082.18 EJP67212.1 - 7.2e-20 71.1 6.1 1.8e-16 60.0 0.6 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain DUF1427 PF07235.11 EJP67212.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) AAA PF00004.29 EJP67213.1 - 8e-08 32.8 1.8 2.7e-07 31.1 1.8 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EJP67213.1 - 7.4e-06 26.0 0.0 0.007 16.3 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 EJP67213.1 - 0.00012 22.6 0.2 0.00028 21.3 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EJP67213.1 - 0.0026 18.3 0.0 0.012 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJP67213.1 - 0.0026 18.0 0.9 0.011 16.0 0.9 2.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EJP67213.1 - 0.022 14.0 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain T2SSE PF00437.20 EJP67213.1 - 0.061 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 EJP67213.1 - 0.084 12.8 0.0 2 8.3 0.0 2.4 1 1 0 1 1 1 0 NTPase Cytidylate_kin PF02224.18 EJP67213.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase DUF815 PF05673.13 EJP67213.1 - 0.098 11.8 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 EJP67213.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Utp8 PF10395.9 EJP67214.1 - 5.6e-08 31.8 2.1 2.5e-07 29.6 1.9 2.1 2 1 0 2 2 2 1 Utp8 family TerB PF05099.13 EJP67214.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TerB CAP_N PF01213.19 EJP67216.1 - 3.6 7.0 10.2 5.6 6.4 10.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_3 PF01596.17 EJP67217.1 - 1.5e-32 112.5 0.0 2.2e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EJP67217.1 - 1.3e-11 45.5 0.0 3.4e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EJP67217.1 - 1.3e-11 44.7 0.0 1.8e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EJP67217.1 - 3.4e-09 36.7 0.0 6.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP67217.1 - 5.1e-08 33.5 0.0 1.3e-07 32.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.10 EJP67217.1 - 0.00035 20.3 0.0 0.0005 19.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 EJP67217.1 - 0.0045 16.4 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltrans_SAM PF10672.9 EJP67217.1 - 0.025 13.8 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Methyltransf_4 PF02390.17 EJP67217.1 - 0.028 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Cyclin PF08613.11 EJP67218.1 - 4.9e-10 40.0 0.0 9.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EJP67218.1 - 0.00063 19.5 0.1 0.0015 18.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chs7 PF12271.8 EJP67219.1 - 1.7e-123 411.6 12.0 1.9e-123 411.4 12.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3716 PF12511.8 EJP67220.1 - 2.4e-07 30.7 9.2 4.4e-07 29.8 9.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Bunya_RdRp PF04196.12 EJP67220.1 - 0.85 7.9 2.8 1.6 7.0 2.8 1.3 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase YABBY PF04690.13 EJP67220.1 - 1.9 9.0 6.0 6.1 7.4 6.0 1.9 1 1 0 1 1 1 0 YABBY protein TMPIT PF07851.13 EJP67220.1 - 1.9 7.7 7.0 2.9 7.1 7.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EJP67220.1 - 3.1 7.1 8.3 5.5 6.2 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 EJP67220.1 - 7 6.1 8.6 16 5.0 8.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit CALM_bind PF16025.5 EJP67221.1 - 0.00065 20.1 0.3 0.00076 19.9 0.3 1.1 1 0 0 1 1 1 1 Calcium-dependent calmodulin binding Ribosomal_60s PF00428.19 EJP67221.1 - 0.051 14.2 0.8 0.064 13.9 0.8 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein LRIF1 PF15741.5 EJP67222.1 - 0.11 11.1 0.7 0.14 10.7 0.7 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF2461 PF09365.10 EJP67222.1 - 0.12 12.4 1.6 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) DUF1501 PF07394.12 EJP67222.1 - 0.19 10.8 2.0 0.26 10.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) NmrA PF05368.13 EJP67223.1 - 1.1e-19 71.0 0.0 1.5e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP67223.1 - 1.6e-16 60.7 0.0 3e-16 59.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EJP67223.1 - 3.7e-05 24.0 0.2 9.2e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EJP67223.1 - 0.00099 18.6 0.2 0.0033 16.9 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EJP67223.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 EJP67223.1 - 0.023 13.7 0.1 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 EJP67223.1 - 0.03 14.5 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 EJP67223.1 - 0.056 12.5 0.1 0.13 11.3 0.1 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 EJP67223.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase LpxI_N PF17930.1 EJP67223.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 LpxI N-terminal domain KR PF08659.10 EJP67223.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 KR domain DUF2070 PF09843.9 EJP67224.1 - 1.7 6.8 8.3 3.3 5.9 8.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short PF00106.25 EJP67225.1 - 2.8e-40 137.8 0.1 7e-40 136.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP67225.1 - 8.6e-29 100.7 0.0 1.4e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP67225.1 - 1.2e-11 44.8 0.7 3.7e-11 43.3 0.7 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EJP67225.1 - 0.00067 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EJP67225.1 - 0.0034 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EJP67225.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 EJP67225.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF829 PF05705.14 EJP67226.1 - 8.8e-52 176.4 0.0 1e-51 176.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) AAA PF00004.29 EJP67227.1 - 3.1e-17 63.2 0.0 5.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EJP67227.1 - 0.00045 20.0 0.0 0.00097 18.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EJP67227.1 - 0.0081 16.6 0.1 0.043 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EJP67227.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EJP67227.1 - 0.047 14.1 0.2 0.17 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 EJP67227.1 - 0.053 13.1 0.0 0.18 11.4 0.0 1.7 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EJP67227.1 - 0.06 13.7 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain Vps36_ESCRT-II PF11605.8 EJP67227.1 - 0.075 13.2 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Zeta_toxin PF06414.12 EJP67227.1 - 0.14 11.4 0.4 0.3 10.4 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 EJP67227.1 - 0.22 10.8 1.2 0.79 9.0 0.7 2.0 1 1 1 2 2 2 0 KaiC ECH_1 PF00378.20 EJP67228.1 - 7.5e-33 113.9 0.0 1.5e-32 112.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP67228.1 - 1.2e-22 80.9 0.4 3.3e-22 79.4 0.4 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Endotoxin_N PF03945.14 EJP67229.1 - 1.5e-14 54.3 0.1 3.2e-13 49.9 0.0 2.5 3 0 0 3 3 3 1 delta endotoxin, N-terminal domain Jacalin PF01419.17 EJP67229.1 - 0.00011 22.1 2.1 0.00017 21.6 0.3 2.0 2 0 0 2 2 2 1 Jacalin-like lectin domain Ank_4 PF13637.6 EJP67230.1 - 6.7e-22 77.6 0.8 1.2e-08 35.4 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP67230.1 - 1.5e-18 67.2 0.0 6.3e-09 36.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP67230.1 - 2.3e-16 58.2 0.1 0.0004 20.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EJP67230.1 - 6.1e-13 48.6 0.0 0.1 13.1 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EJP67230.1 - 5.2e-10 39.4 0.6 1.8e-07 31.3 0.3 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) bZIP_1 PF00170.21 EJP67230.1 - 0.0067 16.5 2.9 0.0067 16.5 2.9 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 EJP67230.1 - 0.027 15.0 5.9 0.056 14.0 5.9 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 EJP67230.1 - 0.047 13.8 4.0 0.081 13.0 4.0 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF4171 PF13775.6 EJP67230.1 - 7.9 6.9 12.6 0.65 10.4 4.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) MFS_1 PF07690.16 EJP67231.1 - 5.3e-45 153.9 45.9 5.3e-45 153.9 45.9 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP67231.1 - 1.1e-13 50.5 12.9 1.1e-13 50.5 12.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Deltameth_res PF16020.5 EJP67231.1 - 2.6 8.0 9.0 14 5.6 0.4 4.1 2 2 1 3 3 3 0 Deltamethrin resistance Ndc1_Nup PF09531.10 EJP67231.1 - 4.1 6.0 8.1 6.7 5.3 8.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup p450 PF00067.22 EJP67232.1 - 1.7e-61 208.4 0.0 2.2e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EJP67233.1 - 6.5e-19 68.1 3.4 1.4e-18 67.0 3.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP67233.1 - 2.1e-10 40.5 1.2 5.2e-10 39.3 1.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EJP67233.1 - 0.0033 16.8 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding adh_short PF00106.25 EJP67234.1 - 6.8e-22 77.9 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP67234.1 - 2.7e-15 56.6 0.0 3.5e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EJP67234.1 - 3.4e-08 33.3 0.0 5.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EJP67234.1 - 4.5e-08 33.2 0.0 7.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EJP67234.1 - 0.00017 21.5 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EJP67234.1 - 0.01 15.3 0.0 0.018 14.4 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Gp_dh_N PF00044.24 EJP67234.1 - 0.08 13.3 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Peripla_BP_1 PF00532.21 EJP67234.1 - 0.084 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PepSY_TM_like_2 PF16357.5 EJP67234.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like Abhydrolase_1 PF00561.20 EJP67235.1 - 1.2e-12 48.1 0.0 1.4e-09 38.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP67235.1 - 7e-12 45.1 0.0 9.4e-10 38.2 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 EJP67235.1 - 1e-09 37.5 0.0 1.5e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 EJP67235.1 - 3.6e-09 37.6 0.0 4.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EJP67235.1 - 4.7e-08 32.9 0.0 1.4e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EJP67235.1 - 1.2e-07 31.4 0.0 4.5e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 EJP67235.1 - 0.00014 21.9 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 EJP67235.1 - 0.00023 21.2 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.13 EJP67235.1 - 0.0013 18.7 0.0 0.0029 17.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.11 EJP67235.1 - 0.0016 17.3 0.0 0.0048 15.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.18 EJP67235.1 - 0.0017 17.9 0.0 0.0042 16.7 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.14 EJP67235.1 - 0.0065 15.8 0.1 0.36 10.1 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase ketoacyl-synt PF00109.26 EJP67236.1 - 3.6e-60 203.7 0.0 6.7e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EJP67236.1 - 3.6e-54 183.4 0.2 2.2e-53 180.9 0.1 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EJP67236.1 - 2.4e-53 181.3 0.0 4.2e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EJP67236.1 - 4.4e-49 167.7 0.1 7.8e-49 166.9 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP67236.1 - 2e-33 114.9 1.1 6.2e-33 113.3 0.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EJP67236.1 - 5.4e-22 79.3 0.0 4.1e-21 76.4 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EJP67236.1 - 1.2e-19 70.5 0.0 6.7e-19 68.2 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EJP67236.1 - 2.7e-19 69.7 0.0 3.2e-18 66.2 0.0 2.7 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EJP67236.1 - 1.1e-12 47.8 1.8 7.9e-09 35.2 0.0 3.5 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP67236.1 - 7.1e-08 32.3 0.3 4.6e-07 29.6 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 EJP67236.1 - 1e-07 31.8 0.1 2.2e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EJP67236.1 - 4.9e-07 30.0 0.1 1.2e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 EJP67236.1 - 1.7e-06 27.9 0.4 4e-06 26.7 0.4 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 EJP67236.1 - 0.021 14.6 0.1 0.067 13.1 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Fungal_trans PF04082.18 EJP67237.1 - 3.6e-16 59.0 0.5 6.9e-16 58.1 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EJP67237.1 - 1.8e-08 34.4 13.2 0.0003 21.1 1.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP67237.1 - 7.4e-07 29.3 11.4 2.4e-06 27.7 6.7 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP67237.1 - 0.00049 20.7 13.0 0.04 14.8 2.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP67237.1 - 0.061 13.6 3.8 0.42 11.0 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 EJP67237.1 - 0.11 12.7 1.9 0.24 11.7 1.9 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain zf-met PF12874.7 EJP67237.1 - 0.27 11.7 5.4 0.62 10.5 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TRAF6_Z2 PF18048.1 EJP67237.1 - 0.84 9.8 5.1 5.7 7.1 2.1 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 CAP PF00188.26 EJP67238.1 - 2.1e-18 67.4 1.3 3.2e-18 66.8 1.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ferritin_2 PF13668.6 EJP67239.1 - 1.7e-07 31.5 2.3 2.8e-07 30.8 2.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4849 PF16141.5 EJP67240.1 - 6.6e-11 42.0 0.0 7.9e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 Putative glycoside hydrolase Family 18, chitinase_18 Glyco_hydro_18 PF00704.28 EJP67240.1 - 9.7e-09 35.4 0.2 1.3e-08 35.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Form_Nir_trans PF01226.17 EJP67241.1 - 4.7e-73 245.4 14.7 5.4e-73 245.2 14.7 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter FB_lectin PF07367.11 EJP67242.1 - 1.5e-57 193.4 0.1 1.7e-57 193.3 0.1 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin Ntox47 PF15540.6 EJP67242.1 - 0.061 13.6 0.3 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial toxin 47 Ldh_1_N PF00056.23 EJP67245.1 - 1.7e-30 106.0 0.0 2.5e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EJP67245.1 - 2.3e-17 63.4 0.0 4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 EJP67245.1 - 0.017 15.7 0.1 0.045 14.3 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EJP67245.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EJP67245.1 - 0.12 12.6 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 EJP67246.1 - 2.5e-30 106.3 0.2 3.3e-30 105.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EJP67246.1 - 1.6e-05 25.0 0.3 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EJP67246.1 - 0.00046 19.5 0.1 0.0079 15.5 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP67246.1 - 0.0026 16.9 0.2 0.026 13.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EJP67246.1 - 0.01 16.1 0.0 0.037 14.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EJP67246.1 - 0.021 13.7 0.0 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EJP67246.1 - 0.08 12.2 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GCV_T PF01571.21 EJP67247.1 - 7.8e-69 231.9 0.1 1.9e-68 230.6 0.0 1.6 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 EJP67247.1 - 2.4e-43 149.1 0.7 4.4e-43 148.2 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 EJP67247.1 - 1.3e-21 76.2 0.2 3.2e-21 75.0 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 EJP67247.1 - 7.7e-20 71.0 0.0 1.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain ThiF PF00899.21 EJP67247.1 - 0.00048 19.5 0.1 0.00089 18.7 0.1 1.3 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.14 EJP67247.1 - 0.0005 19.4 0.3 0.51 9.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP67247.1 - 0.0011 19.4 0.3 0.24 12.0 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EJP67247.1 - 0.0029 17.8 0.2 0.0072 16.6 0.2 1.7 1 0 0 1 1 1 1 TrkA-N domain SoxG PF04268.12 EJP67247.1 - 0.0037 17.4 0.0 0.022 14.9 0.0 2.2 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family Shikimate_DH PF01488.20 EJP67247.1 - 0.017 15.2 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EJP67247.1 - 0.021 14.8 0.9 3.3 7.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EJP67247.1 - 0.036 13.3 0.7 0.14 11.4 0.7 1.9 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 EJP67247.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP67247.1 - 0.04 13.0 0.7 0.096 11.7 0.7 1.6 1 1 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EJP67247.1 - 0.11 11.3 0.4 0.32 9.8 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 EJP67247.1 - 0.17 12.1 0.1 0.67 10.2 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DXP_synthase_N PF13292.6 EJP67247.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Fungal_trans PF04082.18 EJP67248.1 - 5.1e-09 35.5 0.5 8.3e-09 34.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ring_hydroxyl_A PF00848.19 EJP67249.1 - 1.2e-23 84.2 6.8 5.2e-11 42.9 3.1 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EJP67249.1 - 1.8e-16 59.9 0.0 3.7e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain zf-DNA_Pol PF08996.10 EJP67249.1 - 0.044 13.5 0.3 0.14 11.8 0.2 1.8 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger LIP PF03583.14 EJP67250.1 - 4.9e-33 114.7 0.0 9.3e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Secretory lipase An_peroxidase PF03098.15 EJP67251.1 - 2.5e-46 158.4 0.0 1.7e-34 119.3 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EJP67251.1 - 0.0083 14.9 0.0 0.3 9.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF5601 PF18151.1 EJP67251.1 - 0.14 12.5 0.1 0.42 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF2235 PF09994.9 EJP67252.1 - 8.4e-99 330.6 1.1 1.4e-98 329.8 1.1 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Palm_thioest PF02089.15 EJP67252.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Man-6-P_recep PF02157.15 EJP67252.1 - 0.14 11.3 0.2 0.22 10.6 0.2 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor NAD_binding_1 PF00175.21 EJP67253.1 - 6.3e-31 107.2 0.0 1.2e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EJP67253.1 - 2.6e-28 98.3 0.0 4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EJP67253.1 - 4.2e-17 62.1 0.2 8.5e-17 61.1 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EJP67253.1 - 0.00049 20.2 0.0 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EJP67253.1 - 0.0053 17.0 0.0 0.28 11.4 0.0 2.4 1 1 0 2 2 2 1 Siderophore-interacting FAD-binding domain p450 PF00067.22 EJP67254.1 - 1.1e-68 232.1 0.0 1.4e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSCB_C PF07743.13 EJP67254.1 - 0.055 14.0 1.9 5.8 7.5 0.1 2.6 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain PPR_2 PF13041.6 EJP67254.1 - 0.16 12.2 0.1 0.68 10.2 0.1 2.0 1 1 1 2 2 2 0 PPR repeat family Peptidase_M3 PF01432.20 EJP67255.1 - 6.1e-80 269.7 0.0 7.4e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 zf-C2H2_11 PF16622.5 EJP67256.1 - 0.00061 19.5 2.0 0.0017 18.0 2.0 1.9 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 EJP67256.1 - 0.0038 18.0 0.6 0.0038 18.0 0.6 5.7 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP67256.1 - 0.0088 16.4 0.5 0.0088 16.4 0.5 5.2 6 0 0 6 6 6 2 Zinc finger, C2H2 type PHBC_N PF12551.8 EJP67256.1 - 0.023 14.5 0.1 0.057 13.2 0.1 1.7 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal zf-C2H2_jaz PF12171.8 EJP67256.1 - 0.12 12.7 2.9 0.23 11.8 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CCDC14 PF15254.6 EJP67256.1 - 0.12 11.0 1.7 0.17 10.5 1.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DUF629 PF04780.12 EJP67256.1 - 0.67 8.4 2.2 1 7.8 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) KAR9 PF08580.10 EJP67256.1 - 0.85 8.1 3.9 1.2 7.6 3.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 FMN_red PF03358.15 EJP67257.1 - 1.3e-22 80.2 0.0 2.1e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EJP67257.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold PAN_1 PF00024.26 EJP67258.1 - 3.2e-24 84.7 39.1 2e-06 27.6 0.3 5.4 5 0 0 5 5 5 5 PAN domain PAN_3 PF08277.12 EJP67258.1 - 1.1e-10 41.1 28.1 0.00021 21.0 0.4 5.5 5 0 0 5 5 5 5 PAN-like domain PAN_4 PF14295.6 EJP67258.1 - 6.9e-07 29.1 42.2 0.013 15.4 1.0 6.5 6 0 0 6 6 6 5 PAN domain DEAD PF00270.29 EJP67259.1 - 2.8e-38 131.4 0.0 4.6e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP67259.1 - 4.1e-31 107.6 0.7 4e-30 104.4 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP67259.1 - 7.5e-06 26.0 0.0 2.6e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 EJP67259.1 - 0.012 14.0 1.1 0.014 13.8 0.3 1.3 1 1 0 1 1 1 0 CDC45-like protein Glyco_hydro_16 PF00722.21 EJP67260.1 - 8.9e-45 152.3 6.8 1.3e-44 151.8 6.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EJP67260.1 - 0.097 13.2 11.3 0.23 12.0 11.3 1.6 1 0 0 1 1 1 0 Chitin recognition protein Sulfotransfer_4 PF17784.1 EJP67261.1 - 1.5e-61 208.0 0.1 1.8e-61 207.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EJP67261.1 - 4.3e-06 27.3 0.8 0.00078 19.9 0.1 2.5 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EJP67261.1 - 0.021 14.3 0.0 3.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase domain NAD_binding_10 PF13460.6 EJP67262.1 - 4.3e-12 46.3 0.0 8.4e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Lactonase PF10282.9 EJP67263.1 - 7.1e-52 176.8 0.0 9.5e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 EJP67263.1 - 0.047 12.2 0.0 0.18 10.3 0.0 1.8 1 1 1 2 2 2 0 Cytochrome D1 heme domain MFS_1 PF07690.16 EJP67264.1 - 6.6e-10 38.4 50.1 1.9e-09 37.0 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP67264.1 - 2.8e-05 23.2 13.8 2.8e-05 23.2 13.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter FAD_binding_4 PF01565.23 EJP67265.1 - 2.4e-21 75.9 6.9 3.9e-21 75.2 5.7 1.9 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 EJP67265.1 - 0.00049 20.2 1.0 0.001 19.2 1.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like TetR_C_15 PF17918.1 EJP67265.1 - 0.054 14.2 5.6 10 6.9 0.1 3.3 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NitrOD1 PF18549.1 EJP67265.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 DUF4834 PF16118.5 EJP67266.1 - 0.042 14.8 0.0 0.062 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) HemY_N PF07219.13 EJP67266.1 - 0.079 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Amnionless PF14828.6 EJP67266.1 - 0.099 11.5 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Amnionless FixS PF03597.15 EJP67266.1 - 0.75 9.6 5.8 2.3 8.0 2.7 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Podoplanin PF05808.11 EJP67266.1 - 8.2 6.5 7.0 0.88 9.7 1.8 1.9 1 1 1 2 2 2 0 Podoplanin Aldo_ket_red PF00248.21 EJP67267.1 - 2.8e-40 138.4 0.0 7.5e-40 136.9 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family SNF2_N PF00176.23 EJP67268.1 - 6.5e-71 238.9 0.0 1.1e-70 238.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EJP67268.1 - 8.3e-24 83.4 0.0 2.7e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.31 EJP67268.1 - 5.9e-14 52.4 0.0 1.3e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP67268.1 - 1e-08 35.4 0.0 2.5e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EJP67268.1 - 0.00091 19.0 8.2 0.0017 18.2 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP67268.1 - 0.0011 18.8 5.7 0.002 17.9 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJP67268.1 - 0.0019 18.0 6.2 0.0041 16.9 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP67268.1 - 0.03 14.6 8.9 0.075 13.4 8.9 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 EJP67268.1 - 0.088 12.9 8.5 0.19 11.8 8.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EJP67268.1 - 0.23 11.5 8.1 0.49 10.4 8.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EJP67268.1 - 7.2 6.9 6.2 19 5.5 6.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.19 EJP67269.1 - 6.4e-54 183.2 0.1 8.1e-54 182.9 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Ribosomal_S6 PF01250.17 EJP67270.1 - 4.1e-23 81.5 0.0 4.7e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Baculo_DNA_bind PF04786.12 EJP67270.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein Cullin_binding PF03556.15 EJP67271.1 - 1.7e-32 112.4 5.5 3.8e-32 111.2 5.5 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EJP67271.1 - 1e-08 34.9 0.1 2.3e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain Phage_lambda_P PF06992.11 EJP67271.1 - 0.076 12.7 0.8 41 3.8 0.1 3.4 3 1 0 3 3 3 0 Replication protein P PTCB-BRCT PF12738.7 EJP67272.1 - 2.9e-43 145.6 0.2 1.8e-17 63.0 0.1 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 EJP67272.1 - 7.5e-38 128.8 0.0 8.8e-10 38.8 0.0 4.3 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EJP67272.1 - 2.1e-20 72.9 0.1 6.1e-05 23.4 0.0 4.4 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EJP67272.1 - 6.8e-08 32.7 1.8 0.045 14.1 0.0 3.9 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EJP67272.1 - 0.0065 16.5 0.0 4.7 7.3 0.0 3.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EJP67272.1 - 0.0091 15.9 0.0 8.4 6.3 0.0 3.8 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PIG-L PF02585.17 EJP67273.1 - 1.4e-26 93.7 0.0 2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase CENP-B_dimeris PF09026.10 EJP67274.1 - 0.017 15.5 0.1 0.029 14.7 0.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EJP67274.1 - 0.019 15.3 0.1 0.04 14.3 0.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 EJP67274.1 - 0.071 12.8 1.9 0.089 12.5 1.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Dicty_REP PF05086.12 EJP67274.1 - 0.69 7.8 2.4 0.92 7.4 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF202 PF02656.15 EJP67275.1 - 0.094 13.2 1.1 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Nha1_C PF08619.10 EJP67276.1 - 2.1e-122 409.7 34.7 2.6e-122 409.4 34.7 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EJP67276.1 - 2.3e-74 250.5 23.7 2.7e-74 250.2 23.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EJP67276.1 - 1.5 9.0 4.2 0.74 9.9 0.5 2.3 2 0 0 2 2 2 0 YrhC-like protein PRP4 PF08799.11 EJP67276.1 - 2.9 7.5 8.4 7.9 6.1 1.6 2.7 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Beta-lactamase PF00144.24 EJP67278.1 - 3.1e-39 135.1 1.2 3.1e-39 135.1 1.2 1.4 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 EJP67278.1 - 3.8e-05 24.1 0.0 8.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF2508 PF10704.9 EJP67278.1 - 0.21 11.8 0.2 7.4 6.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) ABC_tran PF00005.27 EJP67280.1 - 3.3e-48 163.7 0.2 1.2e-29 103.6 0.1 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EJP67280.1 - 5.2e-23 82.1 34.1 4.1e-14 52.9 15.7 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP67280.1 - 1e-10 41.4 1.3 0.0041 16.6 0.2 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP67280.1 - 1.4e-07 31.2 0.5 0.02 14.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EJP67280.1 - 3.2e-07 31.1 0.1 0.00037 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP67280.1 - 3.2e-06 27.6 1.4 0.04 14.3 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EJP67280.1 - 3.1e-05 23.9 0.0 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EJP67280.1 - 3.7e-05 23.4 0.0 0.24 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EJP67280.1 - 5.7e-05 23.1 2.4 0.76 9.5 1.0 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EJP67280.1 - 6.6e-05 23.2 0.3 0.45 10.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 EJP67280.1 - 0.00016 20.8 0.6 0.11 11.5 0.1 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EJP67280.1 - 0.00019 21.5 0.5 0.1 12.7 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EJP67280.1 - 0.00064 19.1 0.0 0.17 11.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.12 EJP67280.1 - 0.00081 18.9 4.2 1.5 8.2 0.6 3.3 3 0 0 3 3 3 2 Poxvirus A32 protein Dynamin_N PF00350.23 EJP67280.1 - 0.0048 17.0 0.4 2 8.4 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 EJP67280.1 - 0.0073 16.9 0.4 0.35 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EJP67280.1 - 0.0077 16.2 0.4 4.1 7.3 0.1 2.6 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 EJP67280.1 - 0.0087 16.2 6.4 0.015 15.4 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 EJP67280.1 - 0.013 15.2 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EJP67280.1 - 0.016 15.4 0.1 5.8 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJP67280.1 - 0.017 14.6 0.3 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 EJP67280.1 - 0.02 14.8 1.0 0.49 10.3 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EJP67280.1 - 0.022 14.5 0.1 4.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EJP67280.1 - 0.033 13.9 0.2 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EJP67280.1 - 0.039 13.7 0.1 7.7 6.2 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein Septin PF00735.18 EJP67280.1 - 0.043 13.1 0.2 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.6 EJP67280.1 - 0.048 13.7 0.2 8.7 6.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 EJP67280.1 - 0.051 13.8 0.2 24 5.3 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2075 PF09848.9 EJP67280.1 - 0.068 12.4 0.1 0.96 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 EJP67280.1 - 0.072 12.7 5.9 1 9.0 1.8 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EJP67280.1 - 0.081 12.6 1.2 9.6 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EJP67280.1 - 0.12 12.6 0.4 26 5.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EJP67280.1 - 0.13 11.4 3.4 1.7 7.8 0.0 3.0 4 0 0 4 4 4 0 NB-ARC domain AAA_19 PF13245.6 EJP67280.1 - 0.14 12.4 0.2 6 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain CbiA PF01656.23 EJP67280.1 - 0.15 12.1 1.8 8.3 6.5 0.5 3.0 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 EJP67280.1 - 0.24 11.6 2.2 1.3 9.3 0.4 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EJP67280.1 - 0.25 11.1 3.2 3 7.6 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 EJP67280.1 - 0.31 10.9 4.3 7 6.5 1.0 2.6 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.9 EJP67280.1 - 0.41 9.5 4.1 3.2 6.6 0.3 2.9 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain ATPase PF06745.13 EJP67280.1 - 0.47 9.8 2.7 18 4.6 0.3 3.0 3 0 0 3 3 3 0 KaiC PduV-EutP PF10662.9 EJP67280.1 - 0.62 9.8 2.7 18 5.1 0.4 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Aa_trans PF01490.18 EJP67281.1 - 6.8e-33 114.0 34.5 1e-32 113.4 34.5 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 EJP67281.1 - 0.0026 16.7 18.1 0.0083 15.0 3.1 2.8 3 0 0 3 3 3 2 Spore germination protein AIG1 PF04548.16 EJP67281.1 - 0.19 11.0 1.0 0.3 10.4 1.0 1.2 1 0 0 1 1 1 0 AIG1 family SUIM_assoc PF16619.5 EJP67281.1 - 0.35 11.0 5.9 0.63 10.1 5.9 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pox_A14 PF05767.12 EJP67281.1 - 0.53 10.5 8.0 0.23 11.6 0.5 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Med3 PF11593.8 EJP67281.1 - 0.62 9.2 3.4 1.2 8.3 3.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GATA PF00320.27 EJP67282.1 - 1.9e-14 53.0 3.3 2.8e-14 52.4 3.3 1.3 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 EJP67282.1 - 0.049 13.7 0.9 0.1 12.7 0.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Arm_3 PF16186.5 EJP67282.1 - 0.13 11.8 0.0 7.4 6.2 0.1 2.2 2 0 0 2 2 2 0 Atypical Arm repeat zf-C2H2_3 PF13878.6 EJP67282.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.7 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO SesA PF17107.5 EJP67283.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ATP13 PF12921.7 EJP67284.1 - 8.1e-26 90.1 0.0 1.7e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression LSM PF01423.22 EJP67285.1 - 8.2e-19 67.1 0.1 9.8e-19 66.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain GTP_EFTU PF00009.27 EJP67286.1 - 5.6e-19 68.4 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EJP67286.1 - 1.5e-10 41.3 0.2 9.7e-10 38.7 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EJP67286.1 - 0.0003 20.9 0.1 0.001 19.2 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP67286.1 - 0.0013 18.7 0.6 0.64 9.9 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase PduV-EutP PF10662.9 EJP67286.1 - 0.018 14.8 0.1 0.88 9.3 0.0 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D3 PF03143.17 EJP67286.1 - 0.021 15.1 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain Dynamin_N PF00350.23 EJP67286.1 - 0.048 13.7 0.2 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 EJP67286.1 - 0.07 13.3 0.0 0.86 9.8 0.0 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TBCC_N PF16752.5 EJP67287.1 - 0.2 12.1 2.4 0.35 11.3 2.4 1.3 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain MFS_1 PF07690.16 EJP67288.1 - 1.7e-35 122.6 58.8 2.7e-33 115.4 58.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP67288.1 - 1e-08 34.1 28.7 1.2e-07 30.5 28.7 2.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EJP67288.1 - 7.3e-07 28.4 36.2 9.6e-05 21.4 7.8 3.7 2 2 1 3 3 3 3 Sugar (and other) transporter Endostatin PF06482.11 EJP67288.1 - 0.0093 15.5 0.2 0.013 15.0 0.2 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DUF2681 PF10883.8 EJP67288.1 - 1.7 9.1 5.8 51 4.4 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Gryzun PF07919.12 EJP67289.1 - 1.7e-223 743.7 0.0 2.1e-223 743.4 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 EJP67289.1 - 5e-86 288.5 0.4 2.2e-81 273.2 0.9 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 EJP67289.1 - 0.00014 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF1622 PF07784.11 EJP67289.1 - 0.22 11.5 0.0 0.55 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) MRP-L27 PF09809.9 EJP67290.1 - 2.7e-18 65.8 0.3 3.1e-18 65.6 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Abhydrolase_3 PF07859.13 EJP67291.1 - 8e-43 146.8 0.1 7.2e-33 114.2 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP67291.1 - 2.3e-13 49.8 0.0 9.3e-13 47.8 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EJP67291.1 - 0.002 17.5 0.0 0.0063 15.8 0.0 1.8 1 0 0 1 1 1 1 Serine aminopeptidase, S33 COesterase PF00135.28 EJP67291.1 - 0.015 14.2 0.2 0.17 10.7 0.2 2.1 1 1 0 1 1 1 0 Carboxylesterase family RVT_1 PF00078.27 EJP67292.1 - 3.1e-05 23.6 0.0 7.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lectin_N PF03954.14 EJP67292.1 - 0.00034 20.4 0.1 0.0015 18.3 0.1 2.1 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain Abhydrolase_6 PF12697.7 EJP67293.1 - 2.2e-12 48.1 6.0 3e-12 47.6 6.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP67293.1 - 1.2e-05 24.7 0.0 2.5e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Glyco_hydro_130 PF04041.13 EJP67293.1 - 0.038 12.9 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase Ndr PF03096.14 EJP67293.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Piwi PF02171.17 EJP67294.1 - 1e-65 221.9 0.0 1.7e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 EJP67294.1 - 6.4e-12 45.6 0.0 2e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 EJP67294.1 - 3.9e-07 29.6 0.0 1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 EJP67294.1 - 2.5e-06 28.2 0.5 3.7e-05 24.3 0.5 2.4 1 1 0 1 1 1 1 N-terminal domain of argonaute GARP PF16731.5 EJP67294.1 - 0.05 13.3 9.8 0.082 12.6 9.8 1.2 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma PAZ PF02170.22 EJP67294.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 PAZ domain ArgoMid PF16487.5 EJP67294.1 - 0.17 12.2 0.6 0.44 10.8 0.6 1.7 1 0 0 1 1 1 0 Mid domain of argonaute Inv-AAD PF18785.1 EJP67295.1 - 2.7e-57 192.2 0.1 3.1e-57 192.0 0.1 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EJP67295.1 - 7.1e-10 38.7 0.0 1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EJP67295.1 - 0.0062 16.4 0.2 0.01 15.7 0.2 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain DnaJ PF00226.31 EJP67296.1 - 1.2e-22 79.8 1.4 3.2e-22 78.4 1.4 1.8 1 0 0 1 1 1 1 DnaJ domain WYL_3 PF18488.1 EJP67296.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 WYL domain Nif11 PF07862.11 EJP67296.1 - 0.63 10.4 6.3 1.2 9.5 0.0 3.9 4 1 0 4 4 4 0 Nif11 domain Stn1 PF10451.9 EJP67297.1 - 1.7e-10 40.3 0.3 0.00033 19.7 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EJP67297.1 - 0.00019 21.3 0.0 0.00042 20.2 0.0 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EJP67297.1 - 0.056 13.3 0.0 0.29 11.0 0.0 2.0 1 1 0 1 1 1 0 RecQ-mediated genome instability protein 2 HRDC PF00570.23 EJP67297.1 - 0.07 13.1 1.3 0.15 12.1 1.3 1.5 1 0 0 1 1 1 0 HRDC domain Glyco_hydro81C PF17652.1 EJP67298.1 - 1.1e-158 528.1 4.1 1.5e-158 527.6 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EJP67298.1 - 6.3e-112 373.9 0.3 1.3e-111 372.9 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Na_Ca_ex PF01699.24 EJP67299.1 - 1.6e-44 151.5 35.9 1.4e-23 83.5 15.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Utp14 PF04615.13 EJP67300.1 - 1.8e-197 658.4 65.1 1.8e-197 658.4 65.1 2.0 1 1 1 2 2 2 1 Utp14 protein DUF3510 PF12022.8 EJP67300.1 - 0.034 14.5 0.8 0.034 14.5 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Fib_alpha PF08702.10 EJP67300.1 - 2.1 8.5 5.4 0.41 10.8 0.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family COX15-CtaA PF02628.15 EJP67301.1 - 1.8e-110 369.1 7.0 2.2e-110 368.8 7.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein zf-Di19 PF05605.12 EJP67302.1 - 0.028 14.7 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Chibby PF14645.6 EJP67302.1 - 0.043 14.2 2.1 0.13 12.7 2.1 1.7 1 0 0 1 1 1 0 Chibby family zf-C2H2_4 PF13894.6 EJP67302.1 - 0.086 13.7 0.1 0.18 12.7 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EJP67302.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Fzo_mitofusin PF04799.13 EJP67302.1 - 1.3 8.6 3.5 3.6 7.1 3.5 1.8 1 0 0 1 1 1 0 fzo-like conserved region SMYLE_N PF18615.1 EJP67302.1 - 1.8 8.0 15.1 0.061 12.9 7.4 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Baculo_PP31 PF05311.11 EJP67302.1 - 2.3 7.7 6.0 0.76 9.2 0.4 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Chromo_shadow PF01393.19 EJP67303.1 - 1.8e-14 53.6 1.9 1.5e-11 44.2 0.1 2.5 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EJP67303.1 - 3.1e-11 43.0 1.0 3.1e-11 43.0 1.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain LBP_BPI_CETP_C PF02886.17 EJP67303.1 - 0.12 11.8 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain DUF4724 PF15852.5 EJP67303.1 - 4.3 7.9 5.1 6.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4724) Suc_Fer-like PF06999.12 EJP67304.1 - 9.2e-70 234.5 0.0 1.1e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Acyltransferase PF01553.21 EJP67305.1 - 1.2e-09 37.9 0.0 2.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase PRA1 PF03208.19 EJP67305.1 - 0.23 11.1 3.8 0.4 10.3 3.8 1.3 1 0 0 1 1 1 0 PRA1 family protein BRAP2 PF07576.12 EJP67306.1 - 1.6e-27 95.6 0.0 2.7e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EJP67306.1 - 2.8e-17 62.8 7.2 6.2e-17 61.7 7.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EJP67306.1 - 1.6e-08 34.7 9.1 1.6e-08 34.7 9.1 2.3 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 EJP67306.1 - 6.7e-07 28.9 6.1 2e-06 27.4 6.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EJP67306.1 - 1.8e-06 27.7 9.2 4.4e-06 26.4 9.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP67306.1 - 2.4e-05 24.3 6.1 0.0002 21.3 6.5 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EJP67306.1 - 2.7e-05 23.9 7.6 7e-05 22.6 7.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP67306.1 - 8.5e-05 22.4 7.1 8.5e-05 22.4 7.1 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EJP67306.1 - 0.00021 21.1 6.3 0.00021 21.1 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EJP67306.1 - 0.00028 21.1 6.4 0.00079 19.7 6.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EJP67306.1 - 0.029 14.4 5.9 0.098 12.7 5.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger WD40_alt PF14077.6 EJP67306.1 - 0.051 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif XhlA PF10779.9 EJP67306.1 - 0.68 10.2 2.8 1 9.6 1.3 2.2 1 1 1 2 2 2 0 Haemolysin XhlA zf-UBP_var PF17807.1 EJP67306.1 - 0.69 9.7 5.9 0.11 12.3 0.5 2.2 2 0 0 2 2 2 0 Variant UBP zinc finger Exonuc_VII_L PF02601.15 EJP67306.1 - 1.4 8.4 11.2 2.1 7.8 11.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EJP67306.1 - 3.1 7.1 9.7 4.9 6.4 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prok-RING_4 PF14447.6 EJP67306.1 - 7.9 6.4 23.6 0.028 14.3 10.5 2.8 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 DUF1664 PF07889.12 EJP67306.1 - 9.8 6.2 7.9 2 8.5 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ubiquitin PF00240.23 EJP67307.1 - 2.4e-95 312.3 10.9 1.6e-33 114.2 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EJP67307.1 - 3e-44 148.7 10.7 1e-15 57.3 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EJP67307.1 - 4.7e-18 65.4 4.9 0.00021 21.7 0.1 4.6 2 2 1 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EJP67307.1 - 5.9e-13 48.6 0.1 0.013 15.4 0.0 3.2 2 1 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EJP67307.1 - 2.1e-12 47.3 1.2 0.012 16.0 0.1 3.1 2 1 1 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EJP67307.1 - 2.9e-11 43.5 0.8 0.017 15.2 0.1 3.8 2 2 1 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EJP67307.1 - 1.6e-09 38.2 0.6 0.04 14.5 0.1 3.1 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EJP67307.1 - 7.6e-06 25.9 11.0 9.8 6.3 0.2 5.3 5 0 0 5 5 5 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 EJP67307.1 - 4.3e-05 23.4 0.3 0.33 10.8 0.0 3.0 1 1 2 3 3 3 2 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 EJP67307.1 - 0.00015 22.1 0.0 11 6.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 EJP67307.1 - 0.0041 17.3 0.5 7.5 6.8 0.0 3.0 3 0 0 3 3 3 1 Domain of Unknown Function with PDB structure (DUF3861) TmoB PF06234.12 EJP67307.1 - 0.0043 17.1 0.5 27 5.0 0.0 3.7 2 2 1 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) TRCF PF03461.15 EJP67307.1 - 0.014 15.8 0.4 8.7 6.8 0.0 3.1 3 0 0 3 3 3 0 TRCF domain ACT_5 PF13710.6 EJP67307.1 - 0.017 15.0 2.0 6.2 6.7 0.0 2.9 3 0 0 3 3 3 0 ACT domain Raf1_HTH PF18579.1 EJP67307.1 - 0.023 14.4 0.0 64 3.3 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain DUF969 PF06149.12 EJP67307.1 - 0.025 14.0 0.0 13 5.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF969) FERM_f0 PF16511.5 EJP67307.1 - 0.045 14.0 2.8 67 3.9 0.1 4.2 3 3 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM YcgR_2 PF12945.7 EJP67307.1 - 0.083 13.0 1.3 17 5.6 0.1 2.6 3 0 0 3 3 3 0 Flagellar protein YcgR Big_7 PF17957.1 EJP67307.1 - 0.084 13.6 0.1 29 5.5 0.0 2.5 3 0 0 3 3 2 0 Bacterial Ig domain ProRS-C_2 PF09181.10 EJP67307.1 - 0.089 12.9 1.8 65 3.8 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal DUF1940 PF09155.10 EJP67307.1 - 0.17 12.0 1.6 70 3.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1940) Tash_PEST PF07708.11 EJP67307.1 - 0.31 11.3 9.6 4.1 7.7 1.5 2.5 2 0 0 2 2 2 0 Tash protein PEST motif DMA PF03474.14 EJP67307.1 - 0.68 9.6 2.8 65 3.2 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Plexin_cytopl PF08337.12 EJP67307.1 - 0.73 8.4 8.0 9.8 4.7 0.5 3.5 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain Zn_clus PF00172.18 EJP67308.1 - 0.0039 17.3 7.4 0.0085 16.2 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4056 PF13265.6 EJP67308.1 - 0.76 9.1 4.3 1.3 8.3 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) His_Phos_2 PF00328.22 EJP67309.1 - 2.8e-38 132.3 0.0 3.8e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Prenyltrans PF00432.21 EJP67310.1 - 1.4e-36 123.9 25.1 1.4e-07 31.1 0.2 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EJP67310.1 - 0.00096 18.3 0.1 0.99 8.4 0.0 2.5 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EJP67310.1 - 0.0083 15.3 0.0 0.052 12.6 0.0 2.2 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain dsrm PF00035.26 EJP67311.1 - 0.018 15.7 0.0 0.043 14.5 0.0 1.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EJP67311.1 - 0.018 15.3 0.1 0.028 14.7 0.1 1.5 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 His_Phos_1 PF00300.22 EJP67313.1 - 1.1e-14 54.6 0.0 3.1e-14 53.1 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AA_kinase PF00696.28 EJP67313.1 - 0.042 13.4 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family VHS PF00790.19 EJP67314.1 - 1.2e-40 138.6 0.9 1.6e-39 134.9 0.0 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EJP67314.1 - 1.7e-14 53.7 5.7 2.9e-14 52.9 5.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EJP67314.1 - 7.8e-05 22.3 15.7 0.0033 17.2 0.9 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 EJP67314.1 - 0.0001 22.5 0.0 0.00024 21.3 0.0 1.7 1 0 0 1 1 1 1 GAT domain RAP80_UIM PF18282.1 EJP67314.1 - 0.24 11.2 2.8 0.61 9.9 1.1 2.3 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Fer4_2 PF12797.7 EJP67314.1 - 2.2 8.5 8.1 4 7.7 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain zf-RING_9 PF13901.6 EJP67314.1 - 2.4 8.1 7.4 4.6 7.2 7.4 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon UCH PF00443.29 EJP67315.1 - 6.9e-36 124.1 0.5 1.3e-35 123.1 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJP67315.1 - 1.1e-14 54.8 1.2 1.7e-13 50.9 1.2 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EJP67315.1 - 1.1e-07 32.3 0.0 2.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Cytochrome_C7 PF14522.6 EJP67315.1 - 0.038 14.0 0.1 0.098 12.7 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c APH PF01636.23 EJP67316.1 - 6.6e-07 29.5 0.1 9.5e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP67316.1 - 0.0014 18.2 0.1 0.0019 17.8 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Enterotoxin_a PF01375.17 EJP67318.1 - 1.6e-20 73.8 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain AMP-binding PF00501.28 EJP67320.1 - 1.1e-82 277.9 0.0 1.5e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Melibiase PF02065.18 EJP67321.1 - 4e-08 32.6 0.0 5e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Melibiase DUF3295 PF11702.8 EJP67322.1 - 1.3e-134 450.3 28.9 1.2e-115 387.7 19.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EJP67322.1 - 6.3e-13 48.3 1.9 1.7e-12 47.0 1.9 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) OPT PF03169.15 EJP67323.1 - 1.2e-116 390.8 41.1 2e-116 390.1 41.1 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein CrgA PF06781.12 EJP67323.1 - 0.035 14.2 0.2 0.16 12.1 0.2 2.2 1 0 0 1 1 1 0 Cell division protein CrgA DUF4231 PF14015.6 EJP67323.1 - 0.046 14.2 0.3 0.3 11.6 0.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4191 PF13829.6 EJP67323.1 - 0.3 10.4 0.7 0.95 8.8 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) zf-CHY PF05495.12 EJP67325.1 - 4.6e-12 46.3 9.7 4.6e-12 46.3 9.7 3.2 2 1 0 2 2 2 1 CHY zinc finger Mu-like_Com PF10122.9 EJP67325.1 - 0.009 15.4 0.2 0.009 15.4 0.2 2.6 3 0 0 3 3 3 1 Mu-like prophage protein Com RWD PF05773.22 EJP67325.1 - 0.026 14.8 0.0 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 RWD domain RTA1 PF04479.13 EJP67326.1 - 1.4e-57 194.7 9.8 1.9e-57 194.2 9.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 EJP67327.1 - 2.7e-10 40.2 6.0 4.6e-10 39.5 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP67327.1 - 7.1e-06 25.1 0.4 1.1e-05 24.4 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cpn60_TCP1 PF00118.24 EJP67328.1 - 4.1e-158 527.1 8.3 4.6e-158 526.9 8.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EJP67328.1 - 0.14 12.3 4.0 9.9 6.4 0.2 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain GTP_EFTU PF00009.27 EJP67329.1 - 7.1e-49 166.0 0.0 1.6e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EJP67329.1 - 1.7e-25 89.1 0.5 3.8e-25 88.0 0.5 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 EJP67329.1 - 3.5e-09 37.0 0.8 9e-09 35.6 0.0 2.1 3 0 0 3 3 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EJP67329.1 - 1.2e-07 31.8 0.0 1.7e-06 28.1 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EJP67329.1 - 1.9e-06 28.1 0.1 9.5e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EJP67329.1 - 0.0061 16.0 0.1 0.71 9.3 0.1 2.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EJP67329.1 - 0.0064 16.7 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 EJP67329.1 - 0.034 13.4 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 EJP67329.1 - 0.11 12.1 0.1 3.5 7.1 0.1 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EJP67329.1 - 0.15 12.1 1.1 7.8 6.5 0.0 3.1 2 1 1 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 EJP67329.1 - 0.23 11.3 1.1 0.71 9.8 0.1 2.3 3 0 0 3 3 3 0 RsgA GTPase CAP PF00188.26 EJP67330.1 - 3.7e-18 66.6 7.0 1e-17 65.1 7.0 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family zf-HC5HC2H PF13771.6 EJP67330.1 - 0.027 14.7 0.1 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain HSP70 PF00012.20 EJP67331.1 - 1.4e-264 878.9 12.3 1.6e-264 878.7 12.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJP67331.1 - 4.9e-17 61.8 2.0 2.9e-16 59.2 0.6 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EJP67331.1 - 0.0048 17.3 4.5 1.2 9.6 0.3 3.5 3 1 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 EJP67331.1 - 0.0055 15.7 0.2 0.33 9.9 0.1 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EJP67331.1 - 0.11 11.8 3.3 0.28 10.4 0.1 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Cornifin PF02389.15 EJP67332.1 - 0.047 13.9 0.7 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 Cornifin (SPRR) family DUF4158 PF13700.6 EJP67332.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) DUF2461 PF09365.10 EJP67333.1 - 5.6e-64 215.9 0.1 8.5e-64 215.3 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Cwf_Cwc_15 PF04889.12 EJP67333.1 - 0.017 14.8 30.0 0.046 13.5 4.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 EJP67333.1 - 0.067 12.6 29.1 0.094 12.1 17.7 2.1 2 0 0 2 2 2 0 SDA1 RNase_H2_suC PF08615.11 EJP67333.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.7 2 1 0 2 2 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) NOA36 PF06524.12 EJP67333.1 - 0.12 11.7 32.9 0.44 9.8 8.6 2.1 2 0 0 2 2 2 0 NOA36 protein DUF2151 PF10221.9 EJP67333.1 - 0.14 10.7 5.5 0.18 10.3 5.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RNA_pol_3_Rpc31 PF11705.8 EJP67333.1 - 0.41 10.8 31.5 0.96 9.7 20.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 EJP67333.1 - 0.63 9.3 24.4 0.14 11.5 13.0 2.2 2 0 0 2 2 2 0 BUD22 PA26 PF04636.13 EJP67333.1 - 1.2 8.0 4.7 1.7 7.5 4.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) STAC2_u1 PF16664.5 EJP67333.1 - 1.7 9.1 6.6 3.9 7.9 6.6 1.6 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Pox_Ag35 PF03286.14 EJP67333.1 - 3 7.6 21.1 6.2 6.6 1.0 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Presenilin PF01080.17 EJP67333.1 - 3.1 6.5 7.5 5.1 5.8 7.5 1.4 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 EJP67333.1 - 4.4 6.7 7.6 7.5 6.0 7.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RXT2_N PF08595.11 EJP67333.1 - 8.4 6.4 22.5 6.4 6.8 3.8 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Exo_endo_phos PF03372.23 EJP67334.1 - 0.00025 20.6 0.0 0.00049 19.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TNT PF14021.6 EJP67335.1 - 8.4e-31 106.4 0.0 1.5e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin Putative_PNPOx PF01243.20 EJP67336.1 - 8.4e-09 35.5 0.0 0.00034 20.7 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 EJP67336.1 - 0.00063 20.0 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EJP67336.1 - 0.0074 16.9 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain KCH PF16944.5 EJP67337.1 - 4e-99 331.5 11.5 4.9e-99 331.2 11.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel CREPT PF16566.5 EJP67337.1 - 0.19 11.9 0.8 0.34 11.1 0.8 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour APH PF01636.23 EJP67338.1 - 3.6e-07 30.4 0.0 2.8e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EJP67339.1 - 1.2e-20 74.0 0.0 3.2e-20 72.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67339.1 - 4e-09 36.2 0.0 2.9e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Dynein_IC2 PF11540.8 EJP67339.1 - 0.041 13.8 0.1 0.6 10.1 0.0 2.6 3 0 0 3 3 3 0 Cytoplasmic dynein 1 intermediate chain 2 LIP PF03583.14 EJP67341.1 - 7.3e-11 41.9 0.1 1.4e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 EJP67341.1 - 2.6e-08 33.4 0.3 2.3e-07 30.3 0.3 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP67341.1 - 2.9e-06 27.1 1.2 1.3e-05 25.0 1.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP67341.1 - 0.00012 22.8 0.4 0.00018 22.2 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EJP67341.1 - 0.0015 18.0 0.3 0.0074 15.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 EJP67341.1 - 0.0086 15.9 0.1 0.11 12.4 0.1 2.2 2 0 0 2 2 2 1 Lipase (class 3) DLH PF01738.18 EJP67341.1 - 0.048 13.2 0.0 0.91 9.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family adh_short_C2 PF13561.6 EJP67342.1 - 1.1e-58 198.5 0.8 1.5e-58 198.1 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP67342.1 - 7.3e-47 159.4 1.0 9.4e-47 159.0 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP67342.1 - 8.9e-14 51.8 2.2 1.5e-13 51.0 2.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP67342.1 - 0.08 12.4 0.3 0.16 11.4 0.3 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF681 PF05080.12 EJP67343.1 - 0.079 13.6 0.2 1.1 9.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF681) ParA PF10609.9 EJP67344.1 - 2.8e-88 295.5 0.1 3.7e-88 295.1 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EJP67344.1 - 2.8e-10 40.3 0.0 2e-08 34.3 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EJP67344.1 - 2.8e-05 23.5 0.0 0.00037 19.9 0.1 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EJP67344.1 - 0.00016 21.7 0.2 0.0013 18.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EJP67344.1 - 0.00035 19.8 1.1 0.00065 19.0 0.4 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 EJP67344.1 - 0.0014 18.2 0.2 0.0026 17.4 0.2 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EJP67344.1 - 0.0036 16.3 0.1 0.0064 15.5 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 EJP67344.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 EJP67344.1 - 0.12 12.2 0.7 0.33 10.8 0.4 1.8 2 0 0 2 2 2 0 RsgA GTPase CLP1_P PF16575.5 EJP67344.1 - 0.18 11.6 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SAM_decarbox PF01536.16 EJP67345.1 - 4e-134 447.1 0.0 4.8e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Nop10p PF04135.12 EJP67346.1 - 1.8e-20 72.7 0.1 2e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.11 EJP67347.1 - 1.8e-32 111.3 1.7 3e-32 110.6 1.7 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EJP67347.1 - 1.2e-28 99.4 0.0 2.3e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease WRNPLPNID PF15017.6 EJP67347.1 - 0.0009 20.1 3.7 0.0009 20.1 3.7 2.0 2 0 0 2 2 2 1 Putative WW-binding domain and destruction box PIN_5 PF08745.11 EJP67347.1 - 0.0065 15.9 0.1 6.3 6.2 0.0 3.1 2 1 1 3 3 3 1 PINc domain ribonuclease Rhodanese_C PF12368.8 EJP67347.1 - 0.045 14.1 0.4 0.082 13.3 0.4 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal zf-NADH-PPase PF09297.11 EJP67347.1 - 0.066 12.9 0.7 0.066 12.9 0.7 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 EJP67347.1 - 0.071 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.16 EJP67347.1 - 0.47 10.5 2.9 7.9 6.6 0.6 2.9 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Aa_trans PF01490.18 EJP67348.1 - 9.3e-56 189.3 28.8 1.1e-55 189.1 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MR_MLE_C PF13378.6 EJP67349.1 - 1.3e-62 211.3 0.4 2e-62 210.6 0.4 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EJP67349.1 - 2.1e-06 27.9 0.0 3.1e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Y_phosphatase PF00102.27 EJP67349.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PA PF02225.22 EJP67350.1 - 0.0032 17.5 0.0 0.35 10.9 0.0 3.1 2 1 1 3 3 3 1 PA domain Aldo_ket_red PF00248.21 EJP67351.1 - 5.6e-46 157.1 0.0 3.4e-44 151.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TcpQ PF10671.9 EJP67351.1 - 0.022 14.9 0.1 0.046 13.9 0.1 1.5 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Enterotoxin_a PF01375.17 EJP67352.1 - 6.5e-06 25.9 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain HET PF06985.11 EJP67354.1 - 6.9e-12 45.9 0.7 2.2e-11 44.3 0.7 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.27 EJP67355.1 - 5.9e-47 157.5 0.2 1e-21 76.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans_2 PF11951.8 EJP67356.1 - 9.1e-05 21.4 0.0 0.00018 20.4 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67356.1 - 0.00023 21.2 6.8 0.00044 20.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rtf2 PF04641.12 EJP67357.1 - 3.9e-46 157.5 0.1 1e-45 156.2 0.1 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 EJP67357.1 - 0.0086 16.0 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EJP67357.1 - 0.032 14.0 0.9 0.8 9.5 0.0 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 EJP67357.1 - 0.055 13.8 0.1 0.13 12.7 0.1 1.7 1 1 0 1 1 1 0 Ring finger domain Zn-ribbon_8 PF09723.10 EJP67357.1 - 0.099 12.8 1.2 0.26 11.4 1.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_UBOX PF13445.6 EJP67357.1 - 0.12 12.4 2.4 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger FAT PF02259.23 EJP67358.1 - 4.6e-132 440.4 7.2 1e-131 439.3 7.2 1.7 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 EJP67358.1 - 2.2e-75 252.0 3.2 1.3e-68 230.0 0.2 5.7 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 EJP67358.1 - 1.1e-71 241.6 0.1 1.9e-71 240.8 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EJP67358.1 - 5.2e-45 151.9 0.4 5.2e-45 151.9 0.4 3.7 4 0 0 4 4 3 1 FKBP12-rapamycin binding domain HEAT PF02985.22 EJP67358.1 - 5.6e-19 66.6 14.2 9.2e-05 22.4 0.0 11.4 12 0 0 12 12 11 4 HEAT repeat HEAT_2 PF13646.6 EJP67358.1 - 4.1e-16 59.1 13.6 2.1e-05 24.8 0.1 9.3 10 1 0 10 10 8 4 HEAT repeats HEAT_EZ PF13513.6 EJP67358.1 - 2.4e-13 50.3 12.8 4.2e-05 24.0 0.0 9.8 8 3 3 11 11 10 3 HEAT-like repeat FATC PF02260.20 EJP67358.1 - 6e-13 48.4 0.1 1.8e-12 46.9 0.1 1.9 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.7 EJP67358.1 - 3.6e-09 36.9 1.0 1.1 9.3 0.0 6.6 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EJP67358.1 - 5.9e-08 33.2 0.0 2.3 8.8 0.0 7.4 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EJP67358.1 - 2.6e-06 26.3 5.6 0.0044 15.7 0.1 5.9 5 1 0 5 5 5 1 Adaptin N terminal region CLASP_N PF12348.8 EJP67358.1 - 4.8e-05 23.0 6.0 5.4 6.5 0.0 6.5 6 1 1 7 7 7 1 CLASP N terminal Dopey_N PF04118.14 EJP67358.1 - 0.02 14.0 3.1 0.032 13.4 0.4 2.6 3 0 0 3 3 3 0 Dopey, N-terminal ANAPC3 PF12895.7 EJP67358.1 - 0.057 13.6 2.6 16 5.8 0.0 4.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Baculo_PEP_C PF04513.12 EJP67358.1 - 0.36 10.9 4.3 0.41 10.7 0.0 3.3 4 0 0 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Amidohydro_3 PF07969.11 EJP67359.1 - 2.6e-36 126.1 0.1 3.7e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EJP67359.1 - 5.2e-06 26.0 0.0 0.0075 15.6 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family p450 PF00067.22 EJP67360.1 - 2.5e-72 244.1 0.0 3.1e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MARVEL PF01284.23 EJP67361.1 - 9.7e-10 38.6 11.6 1.3e-09 38.2 11.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain NADHdh_A3 PF14987.6 EJP67361.1 - 0.12 12.7 0.3 0.48 10.8 0.0 2.0 1 1 1 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DUF1264 PF06884.11 EJP67362.1 - 6.8e-79 263.4 0.1 7.9e-79 263.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) PdxA PF04166.12 EJP67362.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA NMT1 PF09084.11 EJP67363.1 - 2.6e-77 259.6 0.0 3.1e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EJP67363.1 - 0.00015 21.6 0.1 1.5 8.4 0.0 3.4 3 1 1 4 4 4 2 NMT1-like family PBP_like PF12727.7 EJP67363.1 - 0.18 10.9 0.0 0.38 9.9 0.0 1.5 1 1 0 1 1 1 0 PBP superfamily domain Na_H_Exchanger PF00999.21 EJP67364.1 - 6.3e-58 196.4 47.0 9.3e-58 195.8 47.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sugar_tr PF00083.24 EJP67365.1 - 2.3e-115 386.1 25.1 2.8e-115 385.8 25.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP67365.1 - 5.3e-21 74.9 55.3 2e-18 66.4 28.8 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Actin PF00022.19 EJP67366.1 - 1.2e-99 333.7 0.0 1.6e-98 330.0 0.0 2.1 1 1 0 1 1 1 1 Actin Aldo_ket_red PF00248.21 EJP67366.1 - 2.8e-53 181.0 0.0 3.8e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 EJP67367.1 - 7.8e-06 25.7 0.2 5.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EJP67367.1 - 0.03 14.2 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 F-box domain UFD1 PF03152.14 EJP67368.1 - 8e-27 93.8 0.0 5.3e-26 91.1 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EJP67368.1 - 2e-06 27.9 0.1 2e-06 27.9 0.1 3.7 5 0 0 5 5 5 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PRP21_like_P PF12230.8 EJP67368.1 - 0.11 12.3 2.6 2.2 8.1 0.3 2.5 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Zn_ribbon_SprT PF17283.2 EJP67368.1 - 0.18 11.8 4.6 3 7.8 1.0 3.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-TRAF PF02176.18 EJP67368.1 - 3.4 8.4 18.7 0.77 10.5 0.4 3.7 3 0 0 3 3 3 0 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EJP67369.1 - 0.48 10.3 7.8 0.77 9.7 3.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_S49_N PF08496.10 EJP67369.1 - 2.3 8.3 6.4 0.53 10.3 1.8 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Rotamase PF00639.21 EJP67369.1 - 8.2 7.5 6.6 1.3 10.0 1.0 2.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain GCIP PF13324.6 EJP67370.1 - 1.8e-18 67.1 0.0 3.3e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting Dimer_Tnp_Tn5 PF02281.16 EJP67370.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain CDC45 PF02724.14 EJP67370.1 - 0.17 10.1 1.7 0.23 9.7 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 EJP67370.1 - 0.26 11.5 8.2 0.8 10.0 8.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RNA_pol_3_Rpc31 PF11705.8 EJP67370.1 - 0.38 11.0 10.4 0.55 10.5 10.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 EJP67370.1 - 0.49 10.8 12.4 0.93 9.9 12.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Importin_rep_6 PF18829.1 EJP67370.1 - 0.7 10.1 5.7 1.6 8.9 5.7 1.6 1 0 0 1 1 1 0 Importin repeat 6 RXT2_N PF08595.11 EJP67370.1 - 6.4 6.8 7.1 11 6.0 7.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 EJP67370.1 - 6.5 6.4 5.4 14 5.4 5.4 1.5 1 0 0 1 1 1 0 FAM176 family Sugar_tr PF00083.24 EJP67371.1 - 1.1e-68 232.2 18.2 1.2e-57 195.8 5.5 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter PRKCSH-like PF12999.7 EJP67371.1 - 7.1e-38 130.1 4.1 5e-23 81.8 1.3 3.2 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EJP67371.1 - 2.1e-29 102.2 1.5 5.6e-29 100.8 1.5 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein MFS_1 PF07690.16 EJP67371.1 - 7.6e-15 54.7 42.9 2.5e-06 26.7 10.0 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily PRKCSH PF07915.13 EJP67371.1 - 7.8e-11 42.8 0.5 3.5e-10 40.7 0.5 2.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Cep57_MT_bd PF06657.13 EJP67371.1 - 0.15 12.5 3.5 0.84 10.1 0.9 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spot_14 PF07084.12 EJP67371.1 - 0.15 12.2 5.2 0.13 12.4 0.8 2.6 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 ATG27 PF09451.10 EJP67371.1 - 0.25 11.2 5.1 0.051 13.4 0.8 1.9 2 0 0 2 2 2 0 Autophagy-related protein 27 Mod_r PF07200.13 EJP67371.1 - 0.38 10.9 16.7 2.9 8.0 0.7 3.4 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ORF6C PF10552.9 EJP67371.1 - 0.41 10.7 6.8 2.4 8.3 6.4 2.2 1 1 1 2 2 2 0 ORF6C domain Spc24 PF08286.11 EJP67371.1 - 0.82 9.9 17.3 0.46 10.8 1.8 3.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 WD40_alt PF14077.6 EJP67371.1 - 3.2 7.7 5.5 6.8 6.6 0.1 3.1 2 1 1 3 3 3 0 Alternative WD40 repeat motif MFS_1_like PF12832.7 EJP67371.1 - 8.9 5.1 12.2 0.6 8.9 6.0 1.9 1 1 1 2 2 2 0 MFS_1 like family STAT_alpha PF01017.20 EJP67371.1 - 9.6 6.1 9.4 0.54 10.1 3.0 2.2 2 1 0 2 2 2 0 STAT protein, all-alpha domain Glyco_hydro_2_N PF02837.18 EJP67372.1 - 2.2e-14 53.7 0.1 4.8e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EJP67372.1 - 9.8e-13 47.9 0.3 5.9e-12 45.3 0.1 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EJP67372.1 - 5.5e-08 33.5 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EJP67372.1 - 0.0099 16.4 0.8 0.06 13.9 0.4 2.4 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Diphtheria_T PF02764.14 EJP67373.1 - 0.00083 19.4 2.3 0.008 16.2 0.0 2.5 2 0 0 2 2 2 1 Diphtheria toxin, T domain DUF4050 PF13259.6 EJP67373.1 - 1.9 8.8 4.2 4.2 7.6 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) NAD_binding_9 PF13454.6 EJP67375.1 - 8.8e-27 94.0 0.0 1.6e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EJP67375.1 - 5.8e-10 38.9 1.1 1.1e-07 31.5 0.5 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP67375.1 - 4e-09 36.1 0.1 1e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP67375.1 - 2e-05 23.9 0.1 0.012 14.8 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EJP67375.1 - 0.0025 17.5 3.5 0.027 14.1 2.6 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase ChaB PF06150.12 EJP67375.1 - 0.01 16.4 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 ChaB NAD_binding_8 PF13450.6 EJP67375.1 - 0.031 14.5 1.9 0.07 13.4 0.1 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EJP67375.1 - 0.086 11.5 1.2 1.6 7.4 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein HPTransfase PF10090.9 EJP67375.1 - 0.12 12.2 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain Beta-lactamase PF00144.24 EJP67376.1 - 1.8e-29 103.0 0.0 3.1e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Crystall_4 PF17945.1 EJP67377.1 - 5.3e-80 264.0 0.1 1.8e-42 143.7 0.0 3.2 3 0 0 3 3 3 2 Beta/Gamma crystallin Trypsin PF00089.26 EJP67377.1 - 1.1e-07 31.9 0.5 3e-07 30.5 0.5 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP67377.1 - 1.6e-05 25.9 0.1 4.4e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain GFA PF04828.14 EJP67378.1 - 2.4e-09 37.4 1.5 2.4e-09 37.4 1.5 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Asp PF00026.23 EJP67379.1 - 1.2e-35 123.4 0.0 1.7e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP67379.1 - 5e-09 36.7 2.0 4.5e-05 23.8 0.0 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EJP67379.1 - 0.083 12.7 0.0 1.2 8.9 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Zn_clus PF00172.18 EJP67380.1 - 6.9e-10 38.9 12.5 1.2e-09 38.1 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP67380.1 - 0.015 14.4 0.5 0.029 13.4 0.5 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans PF04082.18 EJP67381.1 - 1.5e-10 40.6 0.0 3.8e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67381.1 - 6.6e-07 29.3 10.7 1.3e-06 28.4 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C58 PF03543.14 EJP67381.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Methyltransf_2 PF00891.18 EJP67382.1 - 1.9e-15 56.7 0.1 4.9e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain TPR_12 PF13424.6 EJP67384.1 - 4.8e-34 116.5 17.5 1.2e-12 47.9 0.3 5.2 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EJP67384.1 - 4.9e-21 73.9 19.9 6.3e-07 29.1 0.1 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat NACHT PF05729.12 EJP67384.1 - 9.7e-14 51.6 0.0 2.5e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_MalT PF17874.1 EJP67384.1 - 1.6e-05 24.4 3.4 0.025 14.0 1.8 2.8 1 1 1 2 2 2 2 MalT-like TPR region AAA_16 PF13191.6 EJP67384.1 - 7.5e-05 23.2 0.0 0.0003 21.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP67384.1 - 0.00029 21.1 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_7 PF13176.6 EJP67384.1 - 0.0012 18.7 13.8 0.08 13.0 0.2 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP67384.1 - 0.0058 17.1 6.8 0.74 10.4 0.0 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP67384.1 - 0.019 14.8 0.3 11 6.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EJP67384.1 - 0.02 15.5 13.0 1.1 10.0 0.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EJP67384.1 - 0.087 13.0 7.9 6.7 7.1 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Goodbye PF17109.5 EJP67384.1 - 0.09 13.2 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain TPR_14 PF13428.6 EJP67384.1 - 7.3 7.7 18.3 16 6.6 0.1 6.4 6 1 1 7 7 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 EJP67385.1 - 3.5e-30 104.4 0.0 1.6e-12 47.8 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EJP67385.1 - 1.4e-18 66.5 6.6 0.0041 17.5 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EJP67385.1 - 1.3e-17 63.6 2.4 1.2e-05 25.5 0.2 6.0 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP67385.1 - 1.6e-17 61.8 0.5 0.022 15.3 0.0 7.3 8 0 0 8 8 7 4 Ankyrin repeat Ank_4 PF13637.6 EJP67385.1 - 6.9e-14 52.0 0.3 3.5e-06 27.5 0.1 5.1 2 1 2 5 5 5 3 Ankyrin repeats (many copies) AAA_16 PF13191.6 EJP67385.1 - 2e-08 34.8 0.3 6.2e-08 33.2 0.3 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EJP67385.1 - 1.3e-05 25.1 0.0 4.4e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EJP67385.1 - 0.014 15.7 0.0 0.053 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Cutinase PF01083.22 EJP67385.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase AAA_29 PF13555.6 EJP67385.1 - 0.049 13.4 0.1 0.25 11.1 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Metal_resist PF13801.6 EJP67385.1 - 0.1 12.8 2.0 0.41 10.8 2.0 2.0 1 0 0 1 1 1 0 Heavy-metal resistance Viral_helicase1 PF01443.18 EJP67385.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Asp PF00026.23 EJP67387.1 - 6.2e-55 186.8 3.0 7.3e-55 186.6 3.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP67387.1 - 4.9e-09 36.7 1.0 2.7e-06 27.7 0.0 3.2 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP67387.1 - 0.022 15.4 1.4 9.6 6.9 0.4 3.4 2 1 0 2 2 2 0 Aspartyl protease MFS_1 PF07690.16 EJP67389.1 - 2.8e-39 135.0 21.7 2.8e-39 135.0 21.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 EJP67389.1 - 0.85 9.9 12.1 8.9 6.6 0.1 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Ig_GlcNase PF18368.1 EJP67390.1 - 1.4e-34 118.4 0.3 5.5e-34 116.5 0.0 2.1 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 EJP67390.1 - 5e-08 33.6 0.0 2.2e-07 31.5 0.0 2.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 EJP67390.1 - 0.00012 21.7 1.1 0.001 18.8 0.1 2.8 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 EJP67390.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Lipase_GDSL_lke PF16255.5 EJP67390.1 - 0.077 12.3 0.4 0.15 11.4 0.4 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Pro-kuma_activ PF09286.11 EJP67391.1 - 6.4e-39 133.5 0.0 1.9e-38 131.9 0.0 1.8 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain F-box-like PF12937.7 EJP67395.1 - 0.022 14.7 0.0 0.075 12.9 0.0 2.0 1 0 0 1 1 1 0 F-box-like CobT PF06213.12 EJP67395.1 - 0.027 13.9 12.3 0.02 14.3 10.9 1.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT LRR_4 PF12799.7 EJP67396.1 - 0.0027 18.1 5.5 0.075 13.5 0.4 5.0 5 1 2 7 7 7 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EJP67396.1 - 0.0058 16.5 1.5 0.033 14.1 0.0 3.0 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.6 EJP67396.1 - 1.8 8.4 4.1 14 5.5 0.4 3.8 4 0 0 4 4 4 0 Leucine rich repeat Glyco_hydro_31 PF01055.26 EJP67397.1 - 3e-94 316.7 0.2 3.8e-94 316.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EJP67397.1 - 3e-12 46.7 0.0 7.8e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like Vint PF14623.6 EJP67400.1 - 3.3e-53 179.9 0.0 5e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 EJP67400.1 - 5.6e-22 77.7 0.4 1.1e-21 76.7 0.4 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_3 PF13768.6 EJP67400.1 - 1.6e-10 41.2 0.0 3.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EJP67400.1 - 6.4e-09 36.4 0.1 1.5e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Hint_2 PF13403.6 EJP67400.1 - 0.073 13.4 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Hint domain RabGAP-TBC PF00566.18 EJP67401.1 - 4e-36 124.7 1.4 9.1e-36 123.5 1.4 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EJP67401.1 - 1.7e-08 34.1 0.1 6.9e-06 25.6 0.2 3.2 2 1 0 2 2 2 1 Rab-binding domain (RBD) Mso1_Sec1_bdg PF14475.6 EJP67402.1 - 3.5e-19 68.1 0.1 5.5e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 EJP67403.1 - 1e-39 135.8 2.0 1e-39 135.8 2.0 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EJP67403.1 - 4.8e-27 94.5 14.1 4.8e-27 94.5 14.1 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EJP67403.1 - 3.9e-05 23.2 19.2 4.9e-05 22.9 19.2 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 EJP67403.1 - 0.011 14.3 26.4 0.013 14.1 26.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2462 PF09495.10 EJP67403.1 - 0.012 16.3 5.7 0.13 13.1 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) PYC_OADA PF02436.18 EJP67403.1 - 0.043 13.5 2.1 0.079 12.7 2.0 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain Reovirus_cap PF00979.17 EJP67403.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 SDA1 PF05285.12 EJP67403.1 - 0.66 9.3 30.6 0.92 8.9 30.6 1.2 1 0 0 1 1 1 0 SDA1 Vps55 PF04133.14 EJP67404.1 - 2.2e-44 150.2 9.0 2.5e-44 150.0 9.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Chorismate_bind PF00425.18 EJP67405.1 - 2.4e-69 233.8 0.0 3.2e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EJP67405.1 - 1.2e-22 80.6 0.0 5.5e-22 78.5 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EJP67405.1 - 4e-12 46.5 0.0 1.8e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EJP67405.1 - 0.00057 19.7 0.8 0.0047 16.7 0.8 2.2 1 1 0 1 1 1 1 Peptidase C26 NmrA PF05368.13 EJP67406.1 - 5.8e-11 42.4 0.0 8.4e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP67406.1 - 4.2e-05 23.5 0.2 9.6e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EJP67406.1 - 0.0042 17.0 2.3 1.4 8.8 0.2 2.7 2 1 1 3 3 3 2 KR domain TRAPPC9-Trs120 PF08626.11 EJP67407.1 - 0 1460.1 0.0 0 1459.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit adh_short PF00106.25 EJP67408.1 - 3.8e-21 75.4 0.0 2.5e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP67408.1 - 2.3e-17 63.3 0.0 3.5e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP67408.1 - 0.0053 16.7 0.0 0.023 14.6 0.0 1.9 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EJP67408.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sugar_tr PF00083.24 EJP67409.1 - 1.5e-119 399.8 20.4 1.8e-119 399.6 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP67409.1 - 2.3e-21 76.1 27.8 1.8e-19 69.9 26.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP67409.1 - 0.0012 17.4 0.9 0.0025 16.3 0.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Myosin_N PF02736.19 EJP67409.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain zf-C2H2_11 PF16622.5 EJP67410.1 - 0.03 14.1 0.1 0.074 12.8 0.1 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 EJP67410.1 - 0.47 11.4 7.9 0.63 11.0 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger SNF2_N PF00176.23 EJP67411.1 - 1.4e-63 214.8 0.8 3.4e-63 213.5 0.8 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EJP67411.1 - 5.4e-48 162.8 16.9 5.4e-48 162.8 16.9 4.6 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 EJP67411.1 - 1.9e-20 73.3 0.0 4.2e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP67411.1 - 4.7e-07 30.0 0.0 2.1e-06 27.8 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJP67411.1 - 0.0071 16.1 0.0 0.019 14.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Fe_hyd_lg_C PF02906.14 EJP67411.1 - 0.072 12.8 0.7 0.19 11.4 0.7 1.7 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Acetyltransf_10 PF13673.7 EJP67412.1 - 1.1e-09 38.3 0.3 3.5e-09 36.7 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP67412.1 - 3.1e-08 33.9 1.0 3.1e-08 33.9 1.0 2.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP67412.1 - 5.4e-08 33.2 0.8 1.6e-06 28.4 0.8 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EJP67412.1 - 0.00055 19.7 0.2 0.0064 16.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EJP67412.1 - 0.0012 18.9 0.1 0.0041 17.2 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EJP67412.1 - 0.0067 16.5 2.1 0.0077 16.3 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain DUF4530 PF15039.6 EJP67412.1 - 0.013 15.7 1.9 0.013 15.7 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) FR47 PF08445.10 EJP67412.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein PTPRCAP PF15713.5 EJP67412.1 - 0.024 14.9 15.2 0.44 10.8 1.4 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Cytomega_UL84 PF06284.11 EJP67412.1 - 0.45 8.9 4.9 1.6 7.1 2.4 2.1 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein DUF1738 PF08401.11 EJP67412.1 - 0.55 10.4 6.3 0.71 10.0 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) Radial_spoke PF04712.12 EJP67412.1 - 1.7 7.5 16.2 0.5 9.3 3.2 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein MPP6 PF10175.9 EJP67412.1 - 1.7 9.1 15.3 0.36 11.3 0.2 2.5 2 1 0 2 2 2 0 M-phase phosphoprotein 6 RNA_pol_3_Rpc31 PF11705.8 EJP67412.1 - 3.1 8.0 19.8 1.4 9.1 5.0 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 ABC_tran PF00005.27 EJP67413.1 - 1.2e-46 158.7 0.0 2.1e-23 83.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EJP67413.1 - 2.3e-21 75.6 1.9 2.3e-21 75.6 1.9 2.6 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EJP67413.1 - 3.9e-18 66.3 0.3 0.0015 18.4 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP67413.1 - 4e-10 39.5 0.2 0.1 12.0 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP67413.1 - 1.8e-09 38.4 0.8 0.0097 16.4 0.1 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EJP67413.1 - 1.9e-08 33.9 0.1 0.0025 17.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP67413.1 - 9.4e-07 29.4 0.1 0.013 15.9 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EJP67413.1 - 1.5e-06 28.8 0.0 0.079 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EJP67413.1 - 2.2e-06 27.7 0.0 0.034 13.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EJP67413.1 - 3.6e-06 27.0 0.1 0.025 14.7 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP67413.1 - 4e-06 26.8 0.2 0.0068 16.3 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EJP67413.1 - 2.9e-05 24.5 0.0 0.36 11.2 0.0 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EJP67413.1 - 3e-05 24.3 0.1 0.097 12.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 EJP67413.1 - 6.9e-05 22.8 0.2 0.17 11.8 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_5 PF07728.14 EJP67413.1 - 9.4e-05 22.4 0.0 0.54 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EJP67413.1 - 0.00016 22.0 0.0 0.066 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EJP67413.1 - 0.00067 20.0 0.0 2.5 8.5 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EJP67413.1 - 0.00091 19.4 0.0 0.45 10.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EJP67413.1 - 0.0011 18.6 0.0 0.26 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EJP67413.1 - 0.0024 18.1 0.0 2.8 8.2 0.1 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EJP67413.1 - 0.0038 17.3 0.0 4.1 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EJP67413.1 - 0.0039 16.8 0.0 0.48 10.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF2813 PF11398.8 EJP67413.1 - 0.0043 16.4 0.0 0.88 8.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) Dynamin_N PF00350.23 EJP67413.1 - 0.0046 17.0 0.1 6.8 6.7 0.0 3.3 3 0 0 3 3 3 0 Dynamin family NB-ARC PF00931.22 EJP67413.1 - 0.0059 15.8 0.0 5.6 6.1 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 EJP67413.1 - 0.0063 16.3 0.9 2 8.1 0.0 3.3 4 0 0 4 4 4 1 AAA domain NTPase_1 PF03266.15 EJP67413.1 - 0.037 13.9 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 EJP67413.1 - 0.042 13.6 1.8 1.9 8.2 0.1 3.3 4 1 0 4 4 2 0 AAA domain ATPase_2 PF01637.18 EJP67413.1 - 0.05 13.5 0.0 7.5 6.4 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 EJP67413.1 - 0.061 12.8 0.0 8.1 6.0 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.6 EJP67413.1 - 0.062 13.7 0.0 17 5.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF3584 PF12128.8 EJP67413.1 - 0.064 10.8 0.3 0.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_7 PF12775.7 EJP67413.1 - 0.064 12.8 0.0 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DAP3 PF10236.9 EJP67413.1 - 0.087 12.0 0.1 7.3 5.7 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.13 EJP67413.1 - 0.091 11.9 0.1 6.2 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 EJP67413.1 - 0.096 12.7 0.2 21 5.1 0.0 3.0 2 1 1 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 EJP67413.1 - 0.1 11.4 0.1 16 4.1 0.0 3.1 3 1 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.17 EJP67413.1 - 0.21 11.6 0.7 27 4.8 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain LexA_DNA_bind PF01726.16 EJP67415.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Glyco_hydro_72 PF03198.14 EJP67416.1 - 2e-123 411.7 5.0 2.8e-123 411.2 5.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EJP67416.1 - 8.1e-21 74.5 4.7 9.4e-21 74.3 3.1 2.0 2 0 0 2 2 2 1 X8 domain Glyco_hydro_2_C PF02836.17 EJP67416.1 - 0.00025 20.3 2.8 0.001 18.3 2.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain AAA PF00004.29 EJP67417.1 - 5.6e-41 140.0 0.0 1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EJP67417.1 - 9.8e-12 44.7 0.3 2.1e-11 43.6 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EJP67417.1 - 3.9e-11 42.6 0.3 7.2e-11 41.7 0.3 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EJP67417.1 - 4e-06 27.0 0.0 9.4e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EJP67417.1 - 9.3e-06 26.0 0.1 0.0064 16.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EJP67417.1 - 1.4e-05 24.4 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EJP67417.1 - 0.00016 21.7 0.1 0.00064 19.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EJP67417.1 - 0.00035 21.0 0.1 0.0042 17.5 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EJP67417.1 - 0.00045 20.0 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 EJP67417.1 - 0.0013 18.3 0.4 0.0093 15.6 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 EJP67417.1 - 0.0023 18.5 0.2 0.0055 17.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EJP67417.1 - 0.0055 17.0 1.3 0.0092 16.2 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EJP67417.1 - 0.0076 16.4 0.4 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EJP67417.1 - 0.015 15.1 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 EJP67417.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EJP67417.1 - 0.025 13.8 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EJP67417.1 - 0.029 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain WYL PF13280.6 EJP67417.1 - 0.036 14.1 0.1 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 WYL domain RNA_helicase PF00910.22 EJP67417.1 - 0.054 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EJP67417.1 - 0.058 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EJP67417.1 - 0.069 12.6 0.2 0.5 9.8 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 EJP67417.1 - 0.072 12.4 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 EJP67417.1 - 0.075 12.9 0.1 0.61 10.0 0.1 2.2 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 EJP67417.1 - 0.083 12.2 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 EJP67417.1 - 0.086 12.4 1.1 0.53 9.8 0.4 2.4 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EJP67417.1 - 0.25 11.1 2.5 0.32 10.7 0.3 2.3 2 1 0 2 2 2 0 AAA domain Promethin PF16015.5 EJP67418.1 - 2.2e-25 88.6 14.2 3e-25 88.2 14.2 1.2 1 0 0 1 1 1 1 Promethin TMEM208_SND2 PF05620.11 EJP67418.1 - 0.021 14.6 5.2 0.049 13.4 5.2 1.7 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 SARAF PF06682.12 EJP67418.1 - 0.036 13.7 0.8 0.054 13.1 0.8 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CBP_BcsG PF11658.8 EJP67418.1 - 0.05 12.0 0.1 0.058 11.8 0.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF3767 PF12597.8 EJP67418.1 - 0.4 10.5 5.2 0.82 9.5 5.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3767) DUF4834 PF16118.5 EJP67418.1 - 0.47 11.5 1.6 1.1 10.2 1.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 EJP67418.1 - 3.4 7.2 10.0 4.4 6.9 10.0 1.1 1 0 0 1 1 1 0 Spt20 family HET PF06985.11 EJP67419.1 - 2.5e-34 118.7 0.2 8.1e-34 117.1 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) RicinB_lectin_2 PF14200.6 EJP67420.1 - 5.3e-09 36.7 0.1 4.5e-06 27.3 0.0 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EJP67420.1 - 5.4e-05 23.4 0.0 6.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PAP2 PF01569.21 EJP67421.1 - 4.7e-19 68.5 6.0 4.7e-19 68.5 6.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily MUG113 PF13455.6 EJP67422.1 - 3.4e-22 78.9 0.1 7.1e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EJP67422.1 - 4.8e-22 78.4 0.1 1.1e-21 77.2 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Amino_oxidase PF01593.24 EJP67423.1 - 1.4e-51 176.2 0.0 2e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP67423.1 - 7.9e-12 45.2 0.2 2.6e-11 43.6 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP67423.1 - 4.1e-09 36.0 1.1 8.7e-09 35.0 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EJP67423.1 - 1.4e-05 24.0 2.9 0.00029 19.6 0.1 2.7 2 1 1 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 EJP67423.1 - 7.9e-05 22.1 0.7 0.022 14.0 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP67423.1 - 0.0019 17.5 0.5 0.0043 16.3 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EJP67423.1 - 0.0022 17.4 1.0 0.0038 16.6 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EJP67423.1 - 0.0026 17.4 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP67423.1 - 0.0036 17.8 1.1 0.015 15.9 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP67423.1 - 0.0041 16.4 0.2 0.0074 15.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EJP67423.1 - 0.0048 16.2 1.7 0.0053 16.0 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP67423.1 - 0.013 14.6 1.5 0.016 14.3 0.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EJP67423.1 - 0.023 13.8 0.6 0.3 10.1 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pepsin-I3 PF06394.13 EJP67423.1 - 0.077 13.2 0.1 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF885 PF05960.11 EJP67424.1 - 4.4e-47 161.9 0.3 5.5e-47 161.6 0.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) ArsR PF09824.9 EJP67425.1 - 0.094 12.3 6.7 0.37 10.4 0.2 3.2 3 0 0 3 3 3 0 ArsR transcriptional regulator ATG16 PF08614.11 EJP67425.1 - 0.18 12.0 48.3 1.6 8.9 1.3 5.0 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) DUF3573 PF12097.8 EJP67425.1 - 0.72 8.6 4.1 0.85 8.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Tropomyosin_1 PF12718.7 EJP67425.1 - 0.91 9.7 47.1 0.31 11.2 20.1 4.9 3 1 1 4 4 4 0 Tropomyosin like APG6_N PF17675.1 EJP67425.1 - 1.2 9.6 53.6 0.5 10.9 0.6 5.2 3 1 2 5 5 5 0 Apg6 coiled-coil region RasGEF_N_2 PF14663.6 EJP67425.1 - 1.6 9.2 5.5 4.1 7.8 0.2 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TMF_DNA_bd PF12329.8 EJP67425.1 - 6.1 6.9 47.3 0.47 10.5 0.5 7.2 3 2 4 7 7 7 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 EJP67425.1 - 7.4 5.4 50.6 1.7 7.5 4.6 4.2 3 1 1 4 4 4 0 Spc7 kinetochore protein Metallophos PF00149.28 EJP67426.1 - 3e-29 103.0 0.4 6e-29 102.0 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EJP67426.1 - 1.6e-14 54.5 2.5 1.9e-14 54.3 0.1 2.5 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EJP67426.1 - 9.2e-14 51.8 0.8 9.2e-14 51.8 0.8 2.4 3 1 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EJP67426.1 - 0.03 14.9 0.1 0.078 13.5 0.1 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Amidase PF01425.21 EJP67427.1 - 2.7e-76 257.4 0.0 9.2e-76 255.6 0.0 1.7 1 1 0 1 1 1 1 Amidase Fungal_trans PF04082.18 EJP67428.1 - 4.3e-09 35.8 0.1 6.6e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67428.1 - 0.018 15.1 6.2 0.065 13.4 6.2 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_H_Exchanger PF00999.21 EJP67429.1 - 5.9e-39 133.9 13.8 8.2e-39 133.5 13.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EJP67429.1 - 5.2e-05 23.3 0.7 0.00032 20.7 0.1 2.7 2 0 0 2 2 2 1 YrhC-like protein DUF3382 PF11862.8 EJP67429.1 - 0.045 14.0 1.0 0.19 12.0 1.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Macoilin PF09726.9 EJP67430.1 - 0.88 8.0 11.9 1.2 7.6 11.9 1.1 1 0 0 1 1 1 0 Macoilin family Med21 PF11221.8 EJP67430.1 - 3.9 7.7 7.3 0.39 10.9 1.9 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Peptidase_S28 PF05577.12 EJP67431.1 - 9.3e-47 159.8 0.0 2.1e-46 158.6 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EJP67431.1 - 0.031 13.0 0.2 3 6.4 0.1 2.4 2 1 0 2 2 2 0 PS-10 peptidase S37 DUF2920 PF11144.8 EJP67431.1 - 0.09 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) MFS_1 PF07690.16 EJP67432.1 - 4.6e-38 131.0 28.2 6.3e-38 130.6 28.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Asp PF00026.23 EJP67433.1 - 7.2e-47 160.3 13.6 2.9e-46 158.3 13.6 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EJP67433.1 - 0.00031 20.6 0.1 0.055 13.2 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EJP67433.1 - 0.04 14.2 6.0 0.5 10.6 0.2 2.8 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EJP67433.1 - 0.095 13.3 1.2 12 6.5 0.1 3.5 4 1 0 4 4 4 0 gag-polyprotein putative aspartyl protease EF-hand_4 PF12763.7 EJP67434.1 - 9.8e-11 41.5 0.1 2.5e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EJP67434.1 - 0.0028 17.1 0.0 0.007 15.8 0.0 1.7 1 0 0 1 1 1 1 EF hand ZZ PF00569.17 EJP67434.1 - 3.3 7.6 30.5 0.048 13.5 10.7 3.4 3 0 0 3 3 3 0 Zinc finger, ZZ type Mrx7 PF10906.8 EJP67435.1 - 5.7e-08 32.9 0.0 7.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 MIOREX complex component 7 DUF1993 PF09351.10 EJP67436.1 - 1e-45 155.7 0.0 1.2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF1479 PF07350.12 EJP67437.1 - 6.1e-162 539.1 0.0 7e-162 538.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EJP67437.1 - 0.00036 20.9 0.1 0.41 10.9 0.0 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Cnn_1N PF07989.11 EJP67438.1 - 2.4e-22 78.9 9.7 2.4e-22 78.9 9.7 12.1 8 3 3 12 12 12 4 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 EJP67438.1 - 0.0021 18.3 13.9 0.0021 18.3 13.9 10.6 11 1 0 11 11 11 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Vip3A_N PF12495.8 EJP67438.1 - 0.13 12.2 5.2 0.62 9.9 0.0 3.4 3 1 1 4 4 4 0 Vegetative insecticide protein 3A N terminal Shugoshin_N PF07558.11 EJP67438.1 - 3.1 7.8 25.6 5.4 7.0 0.5 8.0 7 1 1 8 8 8 0 Shugoshin N-terminal coiled-coil region MARVEL PF01284.23 EJP67440.1 - 0.038 14.0 17.8 0.049 13.7 17.0 1.7 1 1 0 1 1 1 0 Membrane-associating domain Arginase PF00491.21 EJP67441.1 - 2e-73 247.4 0.1 2.3e-73 247.1 0.1 1.0 1 0 0 1 1 1 1 Arginase family Pkinase PF00069.25 EJP67442.1 - 3.1e-11 43.2 0.1 1.3e-10 41.1 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EJP67442.1 - 0.00017 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 EJP67442.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP67442.1 - 0.028 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EJP67442.1 - 0.093 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Glyco_transf_90 PF05686.12 EJP67443.1 - 3.7e-13 49.1 1.4 3.5e-08 32.8 0.1 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 RrnaAD PF00398.20 EJP67444.1 - 4.3e-06 26.0 0.0 7.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Transketolase_N PF00456.21 EJP67445.1 - 5.9e-155 515.3 0.0 8.1e-155 514.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EJP67445.1 - 1.7e-44 151.6 0.0 2.8e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EJP67445.1 - 1.5e-12 47.4 0.0 3.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EJP67445.1 - 0.00081 18.7 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 EJP67445.1 - 0.087 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase zf-RING_13 PF17977.1 EJP67445.1 - 0.11 12.7 0.2 0.29 11.3 0.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AAA PF00004.29 EJP67446.1 - 1.7e-41 141.7 0.0 4.2e-41 140.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EJP67446.1 - 4.4e-26 90.7 0.1 2e-25 88.6 0.3 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EJP67446.1 - 1.8e-16 59.9 5.7 1.8e-16 59.9 5.7 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EJP67446.1 - 2.2e-07 30.6 0.0 1.4e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 EJP67446.1 - 4.4e-07 29.8 0.0 7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EJP67446.1 - 1.7e-05 24.9 0.0 0.00022 21.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP67446.1 - 1.8e-05 25.2 0.1 0.0023 18.4 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 EJP67446.1 - 2.3e-05 23.8 0.0 5.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EJP67446.1 - 3.3e-05 23.7 0.0 8.2e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EJP67446.1 - 6.7e-05 23.2 0.0 0.011 16.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 EJP67446.1 - 8.3e-05 22.9 0.1 0.019 15.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 EJP67446.1 - 9.5e-05 21.7 0.1 0.0005 19.3 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EJP67446.1 - 0.00011 22.2 0.0 0.00059 19.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PrkA PF06798.12 EJP67446.1 - 0.00053 19.7 0.0 0.0041 16.8 0.0 2.1 2 0 0 2 2 2 1 PrkA serine protein kinase C-terminal domain AAA_24 PF13479.6 EJP67446.1 - 0.00074 19.3 1.2 0.0067 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EJP67446.1 - 0.00099 19.7 0.1 0.0038 17.8 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EJP67446.1 - 0.0029 17.8 0.0 0.0095 16.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 EJP67446.1 - 0.0086 16.2 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EJP67446.1 - 0.019 15.4 0.0 0.07 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sde2_N_Ubi PF13019.6 EJP67446.1 - 0.023 14.5 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain AAA_25 PF13481.6 EJP67446.1 - 0.024 14.2 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJP67446.1 - 0.027 14.0 0.1 0.13 11.8 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EJP67446.1 - 0.027 13.8 0.0 0.082 12.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 EJP67446.1 - 0.028 14.2 0.2 3.2 7.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TPR_12 PF13424.6 EJP67446.1 - 0.043 14.1 0.9 0.083 13.2 0.3 1.8 2 0 0 2 2 1 0 Tetratricopeptide repeat PhoH PF02562.16 EJP67446.1 - 0.063 12.7 0.5 0.15 11.4 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 EJP67446.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.11 EJP67446.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Torsin Cytidylate_kin PF02224.18 EJP67446.1 - 0.13 12.0 0.3 0.62 9.8 0.1 2.3 2 0 0 2 2 2 0 Cytidylate kinase NACHT PF05729.12 EJP67446.1 - 0.13 12.2 0.0 0.66 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Prefoldin_2 PF01920.20 EJP67447.1 - 7.5e-19 67.6 12.7 8.9e-19 67.4 12.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit WEMBL PF05701.11 EJP67447.1 - 0.0052 15.5 7.4 0.0074 15.0 7.4 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF4201 PF13870.6 EJP67447.1 - 0.0058 16.4 8.4 0.0064 16.2 1.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Prefoldin_3 PF13758.6 EJP67447.1 - 0.012 15.7 3.8 0.017 15.2 3.8 1.2 1 0 0 1 1 1 0 Prefoldin subunit K-box PF01486.17 EJP67447.1 - 0.014 15.6 8.4 1 9.6 0.4 2.2 2 0 0 2 2 2 0 K-box region Fez1 PF06818.15 EJP67447.1 - 0.025 15.0 1.2 0.025 15.0 1.2 2.1 2 0 0 2 2 2 0 Fez1 Spc7 PF08317.11 EJP67447.1 - 0.059 12.2 11.1 0.075 11.9 11.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4164 PF13747.6 EJP67447.1 - 0.086 13.1 5.4 5.3 7.4 0.8 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) PHM7_cyt PF14703.6 EJP67447.1 - 0.11 12.8 5.8 0.17 12.1 5.8 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MIP-T3_C PF17749.1 EJP67447.1 - 0.11 12.4 11.2 1.3 8.9 11.2 2.2 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Spc24 PF08286.11 EJP67447.1 - 0.15 12.3 10.1 1.9 8.8 1.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 YlqD PF11068.8 EJP67447.1 - 0.16 12.3 13.6 0.2 12.0 2.6 2.0 2 0 0 2 2 2 0 YlqD protein LPP PF04728.13 EJP67447.1 - 0.26 11.7 6.9 0.37 11.2 0.9 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Prefoldin PF02996.17 EJP67447.1 - 0.29 11.1 10.9 5.7 6.9 10.9 2.3 1 1 0 1 1 1 0 Prefoldin subunit GAS PF13851.6 EJP67447.1 - 0.33 10.3 13.6 1.2 8.4 13.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding LCIB_C_CA PF18599.1 EJP67447.1 - 0.37 10.1 2.5 0.17 11.2 0.4 1.4 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases FlaC_arch PF05377.11 EJP67447.1 - 0.39 11.1 8.3 1.5 9.3 0.9 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 EJP67447.1 - 1.2 8.5 14.6 0.16 11.4 2.7 1.7 1 1 0 2 2 2 0 Golgin subfamily A member 5 Siah-Interact_N PF09032.11 EJP67447.1 - 1.4 9.3 9.7 3.7 7.9 1.7 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal DUF4407 PF14362.6 EJP67447.1 - 2.2 7.5 10.9 14 4.9 10.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EJP67447.1 - 3.4 7.5 16.9 7.3 6.4 5.2 2.9 2 1 0 2 2 2 0 Septum formation initiator JAB PF01398.21 EJP67448.1 - 2e-14 53.6 0.0 3.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EJP67448.1 - 5.2e-06 26.2 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 EJP67448.1 - 1.9e-05 24.8 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain COesterase PF00135.28 EJP67450.1 - 1.7e-69 235.0 0.0 2.5e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EJP67450.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EJP67450.1 - 0.02 14.8 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chorismate_synt PF01264.21 EJP67451.1 - 4.9e-37 127.4 0.0 5.2e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase OPT PF03169.15 EJP67452.1 - 1.1e-159 532.9 46.4 1.3e-159 532.7 46.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EamA PF00892.20 EJP67453.1 - 0.00059 20.0 12.3 0.00059 20.0 12.3 2.3 2 0 0 2 2 2 1 EamA-like transporter family Peptidase_C1_2 PF03051.15 EJP67453.1 - 0.034 12.9 0.1 0.24 10.1 0.0 1.9 1 1 0 2 2 2 0 Peptidase C1-like family Methyltransf_25 PF13649.6 EJP67454.1 - 8.8e-05 23.1 0.0 0.0016 19.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67454.1 - 0.00046 20.8 0.0 0.0024 18.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP67454.1 - 0.054 13.3 0.0 0.069 13.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Glyco_hydro_32N PF00251.20 EJP67455.1 - 2.6e-77 260.4 5.6 3.2e-77 260.1 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EJP67455.1 - 0.0004 20.4 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Chitin_synth_1 PF01644.17 EJP67456.1 - 3.4e-75 251.5 0.0 5e-75 250.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EJP67456.1 - 1.7e-27 95.1 0.2 3.6e-27 94.1 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EJP67456.1 - 3.5e-23 82.0 4.9 7.9e-20 71.0 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EJP67456.1 - 4e-05 23.6 6.5 0.00023 21.2 6.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 NIR_SIR PF01077.22 EJP67457.1 - 1.9e-53 180.2 0.3 5e-48 162.6 0.1 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EJP67457.1 - 3.5e-30 103.6 0.0 3.3e-14 52.5 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EJP67457.1 - 9.7e-29 100.4 0.0 1.9e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EJP67457.1 - 0.00097 18.9 0.1 0.0022 17.8 0.1 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF4643 PF15485.6 EJP67457.1 - 0.15 11.8 0.1 1.2 8.9 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4643) Kei1 PF08552.11 EJP67458.1 - 2e-57 194.2 10.8 1.2e-56 191.6 10.8 1.9 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.13 EJP67458.1 - 0.83 9.8 8.2 0.073 13.2 1.9 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Rib_5-P_isom_A PF06026.14 EJP67459.1 - 6.7e-44 149.5 0.0 1.4e-43 148.4 0.0 1.5 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EJP67459.1 - 0.006 16.5 0.0 4.2 7.3 0.0 2.5 3 0 0 3 3 3 2 DeoR C terminal sensor domain Ras PF00071.22 EJP67460.1 - 1.8e-58 196.7 0.5 2.4e-58 196.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP67460.1 - 1.9e-36 124.9 0.1 3.4e-36 124.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP67460.1 - 5.4e-18 65.0 0.2 6.7e-18 64.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EJP67460.1 - 1e-06 28.4 0.2 9e-06 25.3 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EJP67460.1 - 1.8e-05 24.3 0.0 2.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EJP67460.1 - 0.00014 21.9 0.0 0.0003 20.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EJP67460.1 - 0.00029 20.2 0.4 0.00039 19.9 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EJP67460.1 - 0.0005 20.0 0.1 0.065 13.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 EJP67460.1 - 0.0026 17.6 0.1 0.0061 16.4 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FlgH PF02107.16 EJP67460.1 - 0.039 13.6 1.2 0.056 13.0 1.2 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein TIR_2 PF13676.6 EJP67460.1 - 0.042 14.5 0.1 0.08 13.6 0.1 1.5 1 0 0 1 1 1 0 TIR domain TetR_C_16 PF17920.1 EJP67460.1 - 0.082 13.2 0.0 0.89 9.8 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Nop53 PF07767.11 EJP67461.1 - 3.6e-110 369.1 27.7 4.6e-110 368.7 27.7 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Pyr_redox_2 PF07992.14 EJP67462.1 - 8.4e-39 133.5 0.0 1.2e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP67462.1 - 2.5e-14 53.6 0.0 4.2e-10 40.1 0.0 3.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EJP67462.1 - 6.7e-07 28.4 0.3 6.7e-07 28.4 0.3 2.0 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EJP67462.1 - 5e-05 22.6 1.4 0.00014 21.2 1.4 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EJP67462.1 - 7e-05 22.5 0.4 7e-05 22.5 0.4 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EJP67462.1 - 0.0002 21.7 0.1 0.00047 20.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair NAD_binding_8 PF13450.6 EJP67462.1 - 0.074 13.3 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PRK PF00485.18 EJP67463.1 - 3.6e-58 196.5 0.0 5.3e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EJP67463.1 - 2.1e-39 135.2 0.0 3.1e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 EJP67463.1 - 4.7e-07 30.3 1.2 0.14 12.6 0.0 3.4 3 0 0 3 3 3 3 AAA domain AAA_33 PF13671.6 EJP67463.1 - 2.2e-06 27.9 0.1 1.6e-05 25.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP67463.1 - 4e-06 27.4 0.0 8.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EJP67463.1 - 4.5e-06 26.6 0.3 2.3e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 EJP67463.1 - 6.3e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 EJP67463.1 - 0.0072 15.5 0.1 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 EJP67463.1 - 0.0099 16.4 0.1 0.024 15.2 0.1 1.6 1 0 0 1 1 1 1 ABC transporter dNK PF01712.19 EJP67463.1 - 0.033 14.0 0.1 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin PF02224.18 EJP67463.1 - 0.036 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase MMR_HSR1 PF01926.23 EJP67463.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EJP67463.1 - 0.053 13.3 0.4 0.14 11.9 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EJP67463.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EJP67463.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 EJP67463.1 - 0.15 12.1 0.0 1.1 9.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) HLH PF00010.26 EJP67464.1 - 4.1e-07 29.9 0.0 7.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CAC1F_C PF16885.5 EJP67464.1 - 0.00022 21.1 2.7 0.00028 20.7 2.7 1.1 1 0 0 1 1 1 1 Voltage-gated calcium channel subunit alpha, C-term DUF4589 PF15252.6 EJP67464.1 - 0.011 15.7 1.5 0.015 15.3 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) PI3K_1B_p101 PF10486.9 EJP67464.1 - 0.016 13.0 2.1 0.016 13.0 2.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Radial_spoke PF04712.12 EJP67464.1 - 0.079 11.9 3.9 0.1 11.5 3.9 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.14 EJP67464.1 - 0.084 11.2 10.7 0.11 10.8 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EJP67464.1 - 0.088 10.9 5.6 0.11 10.6 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 EJP67464.1 - 0.094 13.1 10.1 0.21 12.0 10.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EJP67464.1 - 0.11 12.2 6.9 0.14 11.8 6.5 1.5 1 1 0 1 1 1 0 FAM176 family Apt1 PF10351.9 EJP67464.1 - 0.22 10.4 4.5 0.2 10.5 4.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DNA_pol_phi PF04931.13 EJP67464.1 - 1 7.4 11.1 1.6 6.8 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 EJP67464.1 - 3.2 6.2 5.5 4.4 5.7 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 EJP67464.1 - 5.8 7.4 12.3 1 9.8 4.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 EJP67464.1 - 6.5 6.0 15.9 1.6 8.0 9.3 2.0 2 0 0 2 2 2 0 NOA36 protein EBV-NA3 PF05009.12 EJP67464.1 - 7.7 6.0 6.2 7 6.1 4.9 1.6 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) HsbA PF12296.8 EJP67465.1 - 8.6e-17 61.7 1.0 1.3e-16 61.1 0.1 1.7 2 0 0 2 2 2 1 Hydrophobic surface binding protein A HsbA PF12296.8 EJP67466.1 - 8.4e-22 77.8 2.6 8.4e-22 77.8 2.6 2.8 3 0 0 3 3 3 1 Hydrophobic surface binding protein A HsbA PF12296.8 EJP67467.1 - 3.5e-16 59.7 8.1 3.5e-16 59.7 8.1 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A MFS_1 PF07690.16 EJP67468.1 - 3.2e-21 75.7 29.3 3.2e-21 75.7 29.3 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP67468.1 - 7.1e-08 31.7 32.4 0.0003 19.8 6.4 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter DUF5392 PF17370.2 EJP67468.1 - 0.16 12.0 0.3 0.52 10.4 0.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5392) Mis12 PF05859.12 EJP67470.1 - 4.1e-45 153.2 0.0 1.8e-44 151.0 0.0 2.0 2 0 0 2 2 2 1 Mis12 protein SUIM_assoc PF16619.5 EJP67470.1 - 0.0002 21.4 14.5 0.0074 16.3 0.6 3.9 3 1 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 PPR_2 PF13041.6 EJP67471.1 - 9e-09 35.4 0.1 0.017 15.3 0.0 4.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 EJP67471.1 - 2.9e-08 33.6 0.1 4.6e-06 26.6 0.0 4.2 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 EJP67471.1 - 0.17 11.6 0.0 18 5.2 0.0 2.9 2 0 0 2 2 2 0 PPR repeat GST_N_3 PF13417.6 EJP67472.1 - 1.3e-08 35.1 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EJP67472.1 - 5.8e-07 29.8 0.1 1e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP67472.1 - 9.5e-07 29.0 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EJP67472.1 - 7.8e-06 26.0 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EJP67472.1 - 3.4e-05 24.0 0.0 6.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EJP67472.1 - 7.9e-05 22.6 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EJP67474.1 - 1.2e-07 31.9 0.0 2.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP67474.1 - 3.9e-07 30.0 0.6 8.6e-07 28.9 0.6 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EJP67474.1 - 1.2e-06 28.9 0.0 3.1e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EJP67474.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4246 PF14033.6 EJP67475.1 - 4.5e-171 569.9 0.0 1.1e-170 568.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) BAF1_ABF1 PF04684.13 EJP67475.1 - 0.024 13.7 9.4 0.031 13.3 9.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF-3c_N PF05470.12 EJP67476.1 - 3.8e-173 577.0 20.6 3.8e-173 577.0 20.6 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EJP67476.1 - 2.5e-14 53.7 0.0 1.1e-13 51.6 0.0 2.2 1 0 0 1 1 1 1 PCI domain DUF1617 PF07761.12 EJP67476.1 - 0.016 15.3 0.3 0.059 13.5 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Nop14 PF04147.12 EJP67476.1 - 0.11 10.7 18.8 0.18 10.0 18.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EJP67476.1 - 1.5 7.0 17.0 2.2 6.5 17.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Fe-S_biosyn PF01521.20 EJP67477.1 - 3.4e-13 49.8 0.0 7.1e-12 45.5 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.12 EJP67478.1 - 4.8e-26 90.8 16.6 8.1e-26 90.1 16.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EJP67478.1 - 5.3e-17 61.4 2.7 1.3e-16 60.2 2.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e FRG1 PF06229.12 EJP67478.1 - 0.035 13.8 2.7 0.072 12.8 2.7 1.5 1 0 0 1 1 1 0 FRG1-like domain Ribosomal_S11 PF00411.19 EJP67479.1 - 2.1e-46 156.9 1.7 2.7e-46 156.5 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Pilus_CpaD PF09476.10 EJP67479.1 - 0.042 13.6 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) CBM_25 PF03423.13 EJP67479.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) SNF2_N PF00176.23 EJP67480.1 - 8.4e-68 228.6 0.1 5.7e-67 225.9 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP67480.1 - 1.5e-15 57.4 0.0 4e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP67480.1 - 1.2e-08 35.1 0.0 3.7e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ApbA_C PF08546.11 EJP67481.1 - 8.1e-27 93.9 0.1 1.3e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EJP67481.1 - 4.9e-17 62.0 0.0 8.4e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Myb_DNA-bind_6 PF13921.6 EJP67482.1 - 4.1e-13 49.4 0.2 2.5e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EJP67482.1 - 1.1e-10 41.5 0.1 0.00022 21.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain PROCN PF08083.11 EJP67483.1 - 6.3e-235 779.4 9.1 6.3e-235 779.4 9.1 1.8 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EJP67483.1 - 2.1e-125 416.9 1.4 4.4e-125 415.8 1.4 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EJP67483.1 - 7.4e-84 279.5 2.0 3.2e-57 192.9 0.2 3.0 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EJP67483.1 - 3.9e-78 260.6 2.6 3.9e-78 260.6 2.6 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EJP67483.1 - 7.2e-71 236.5 0.1 1.5e-70 235.5 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EJP67483.1 - 3.4e-46 155.5 0.1 9.6e-46 154.1 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EJP67483.1 - 1.8e-44 150.6 0.1 8.6e-44 148.4 0.0 2.2 2 0 0 2 2 2 1 PROCT (NUC072) domain Hom_end_hint PF05203.16 EJP67483.1 - 3.3e-08 33.8 1.3 6e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Hom_end-associated Hint NDUF_B4 PF07225.12 EJP67484.1 - 0.081 12.8 0.1 0.086 12.7 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SAP18 PF06487.12 EJP67485.1 - 2e-34 118.8 0.0 2.8e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 EJP67486.1 - 3.3e-50 169.9 0.0 3.3e-50 169.9 0.0 2.1 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EJP67486.1 - 2.3e-10 39.8 0.3 2.3e-10 39.8 0.3 2.6 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Caldesmon PF02029.15 EJP67486.1 - 0.0021 16.9 17.6 0.0026 16.6 17.6 1.2 1 0 0 1 1 1 1 Caldesmon PepX_C PF08530.10 EJP67486.1 - 0.59 10.0 4.6 2.9 7.7 3.9 2.2 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Selenoprotein_S PF06936.11 EJP67486.1 - 2.2 8.1 17.4 4.3 7.1 17.4 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Borrelia_P83 PF05262.11 EJP67486.1 - 2.3 6.6 13.0 2.7 6.4 13.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.14 EJP67486.1 - 3.1 6.0 12.4 3.5 5.8 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RPN7 PF10602.9 EJP67487.1 - 3.9e-47 160.2 0.1 8.1e-47 159.2 0.0 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EJP67487.1 - 6.3e-21 74.9 0.1 2.5e-20 72.9 0.1 2.0 2 0 0 2 2 2 1 PCI domain DHC_N2 PF08393.13 EJP67487.1 - 0.00023 20.4 0.0 0.00036 19.8 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 COG2 PF06148.11 EJP67487.1 - 0.096 12.8 0.0 0.85 9.7 0.0 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Trp_oprn_chp PF09534.10 EJP67488.1 - 0.091 12.6 12.4 0.11 12.2 12.4 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4366 PF14283.6 EJP67488.1 - 0.25 11.4 1.4 0.28 11.2 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CNDH2_M PF16869.5 EJP67488.1 - 0.53 11.0 4.7 0.65 10.7 4.7 1.2 1 0 0 1 1 1 0 PF16858 Secretin_N_2 PF07655.13 EJP67488.1 - 0.67 10.5 15.9 0.99 10.0 15.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain FlgH PF02107.16 EJP67488.1 - 1.1 8.9 8.3 1.2 8.7 8.3 1.1 1 0 0 1 1 1 0 Flagellar L-ring protein Macoilin PF09726.9 EJP67488.1 - 2.3 6.7 14.6 2.4 6.6 14.6 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EJP67488.1 - 2.6 6.8 11.2 2.8 6.7 11.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1635 PF07795.11 EJP67488.1 - 2.6 7.8 6.9 2.9 7.7 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DLIC PF05783.11 EJP67488.1 - 5.4 5.7 9.2 5.5 5.7 9.2 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF1180 PF06679.12 EJP67488.1 - 5.4 7.4 13.3 6 7.3 13.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Fungal_trans PF04082.18 EJP67489.1 - 3.4e-30 105.0 0.0 3.4e-30 105.0 0.0 1.7 2 0 0 2 2 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67489.1 - 2.7e-07 30.6 8.3 2.7e-07 30.6 8.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EJP67489.1 - 0.00052 20.1 53.6 0.00052 20.1 53.6 1.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 EJP67489.1 - 0.0076 16.1 15.0 0.014 15.2 15.0 1.4 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EJP67489.1 - 0.013 15.6 11.3 0.036 14.2 11.3 1.7 1 0 0 1 1 1 0 DDHD domain Acid_PPase PF12689.7 EJP67489.1 - 1.2 8.9 6.1 2.8 7.8 6.1 1.5 1 0 0 1 1 1 0 Acid Phosphatase Noggin PF05806.12 EJP67489.1 - 1.7 8.5 9.2 4 7.3 9.2 1.6 1 0 0 1 1 1 0 Noggin Presenilin PF01080.17 EJP67489.1 - 2.1 7.0 29.3 3.5 6.3 29.3 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 EJP67489.1 - 2.9 6.1 43.6 5.7 5.1 43.6 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 EJP67489.1 - 3.3 4.7 21.5 4.7 4.2 21.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AIF_C PF14721.6 EJP67489.1 - 3.7 7.9 13.8 9.6 6.6 13.8 1.8 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zip PF02535.22 EJP67489.1 - 8.1 5.6 7.2 16 4.6 7.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 EJP67489.1 - 9.9 5.5 20.5 17 4.8 20.5 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CHRD PF07452.12 EJP67490.1 - 2.9e-11 44.4 0.3 4.4e-11 43.8 0.0 1.5 2 0 0 2 2 2 1 CHRD domain SET PF00856.28 EJP67491.1 - 3.8e-08 33.9 0.1 3.5e-07 30.8 0.1 2.3 1 1 0 1 1 1 1 SET domain TPR_16 PF13432.6 EJP67491.1 - 0.02 15.5 0.5 0.099 13.3 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 EJP67491.1 - 0.22 11.9 0.4 9.5 6.7 0.0 3.4 3 0 0 3 3 3 0 PPR repeat SOG2 PF10428.9 EJP67493.1 - 2.1 7.5 6.5 1.8 7.7 4.9 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein MSA-2c PF12238.8 EJP67493.1 - 8.4 6.3 8.1 48 3.9 8.5 2.0 3 0 0 3 3 3 0 Merozoite surface antigen 2c Peptidase_M24 PF00557.24 EJP67495.1 - 4.1e-57 193.2 0.2 5.9e-57 192.7 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EJP67495.1 - 3.9e-18 65.3 0.0 1.3e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Lectin_leg-like PF03388.13 EJP67496.1 - 3.5e-24 85.4 0.0 5.2e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family NPV_P10 PF05531.12 EJP67496.1 - 0.0027 18.1 0.3 0.055 13.9 0.1 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EJP67496.1 - 0.013 15.6 0.2 0.024 14.7 0.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2353 PF09789.9 EJP67496.1 - 0.047 13.1 2.9 0.074 12.4 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) PI_PP_C PF18365.1 EJP67496.1 - 0.072 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain FAM76 PF16046.5 EJP67496.1 - 0.081 12.3 0.6 0.13 11.6 0.6 1.2 1 0 0 1 1 1 0 FAM76 protein AIP3 PF03915.13 EJP67496.1 - 0.096 11.8 2.3 0.14 11.2 2.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Prefoldin_2 PF01920.20 EJP67496.1 - 0.14 12.1 0.2 1.6 8.7 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit FUSC PF04632.12 EJP67496.1 - 0.17 10.4 6.0 0.24 9.9 6.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WXG100 PF06013.12 EJP67496.1 - 0.24 11.7 2.8 3.2 8.1 2.8 2.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG KxDL PF10241.9 EJP67496.1 - 0.48 10.7 2.5 1.1 9.5 2.3 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein FlxA PF14282.6 EJP67496.1 - 2.1 8.4 8.6 0.4 10.7 0.5 2.3 2 0 0 2 2 2 0 FlxA-like protein Alg6_Alg8 PF03155.15 EJP67497.1 - 6.7e-177 589.3 28.1 7.8e-177 589.1 28.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Sulfotransfer_4 PF17784.1 EJP67498.1 - 1.3e-55 188.5 0.0 1.7e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EJP67498.1 - 2e-05 25.1 0.0 2.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family WAC_Acf1_DNA_bd PF10537.9 EJP67499.1 - 3.7e-21 75.5 5.6 4.1e-12 46.5 0.0 3.4 2 1 1 3 3 3 2 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EJP67499.1 - 8.7e-18 64.6 0.1 8.7e-18 64.6 0.1 3.9 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EJP67499.1 - 1.2e-15 57.5 0.4 2.4e-15 56.6 0.4 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EJP67499.1 - 2e-11 43.1 0.1 9e-11 41.0 0.0 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 PEX11 PF05648.14 EJP67500.1 - 6.1e-05 22.6 2.0 0.017 14.6 0.2 2.5 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Sgf11 PF08209.11 EJP67500.1 - 0.17 11.5 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Hemerythrin PF01814.23 EJP67501.1 - 2e-10 41.4 3.5 3e-10 40.8 3.5 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PGDH_C PF16896.5 EJP67502.1 - 0.1 12.6 0.8 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 Phosphogluconate dehydrogenase (decarboxylating) C-term TauD PF02668.16 EJP67503.1 - 1.1e-24 87.7 0.0 1.5e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CTP_transf_like PF01467.26 EJP67504.1 - 1.6e-17 64.0 1.3 2.1e-13 50.7 0.0 4.4 4 1 1 5 5 5 3 Cytidylyltransferase-like His_Phos_1 PF00300.22 EJP67505.1 - 2.1e-09 37.4 0.0 1.5e-08 34.6 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SH3_5 PF08460.10 EJP67505.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Ank_2 PF12796.7 EJP67507.1 - 2.4e-70 233.1 14.1 6.3e-17 62.0 0.0 8.3 2 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP67507.1 - 4.6e-59 196.1 15.6 2.9e-11 43.7 0.0 9.5 5 3 3 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP67507.1 - 1.2e-49 160.5 16.8 0.00079 19.7 0.0 14.6 15 0 0 15 15 14 11 Ankyrin repeat Ank PF00023.30 EJP67507.1 - 8.5e-48 158.8 18.0 0.00017 21.9 0.0 13.7 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 EJP67507.1 - 4.1e-36 122.6 15.0 3.2e-06 27.3 0.0 10.2 5 3 5 10 10 10 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 EJP67507.1 - 1.2e-10 41.1 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 EJP67507.1 - 2.9e-06 27.8 0.0 1.8e-05 25.2 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EJP67507.1 - 0.0021 18.0 0.0 0.0072 16.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EJP67507.1 - 0.0076 16.0 0.0 0.033 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EJP67507.1 - 0.0096 16.2 0.0 0.04 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EJP67507.1 - 0.049 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EJP67507.1 - 0.085 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain FNIP_M PF14637.6 EJP67507.1 - 0.11 12.4 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain PCRF PF03462.18 EJP67509.1 - 1.3e-44 152.4 0.6 2.4e-44 151.5 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EJP67509.1 - 5.2e-35 119.9 2.7 1.2e-34 118.8 2.7 1.6 1 0 0 1 1 1 1 RF-1 domain MFS_1 PF07690.16 EJP67511.1 - 2.3e-21 76.1 55.6 1.8e-19 69.9 43.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1673 PF07895.11 EJP67511.1 - 6.2 6.5 11.2 0.3 10.8 4.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) GST_N_3 PF13417.6 EJP67513.1 - 5.2e-14 52.4 0.0 1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP67513.1 - 1.8e-13 50.6 0.0 2.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EJP67513.1 - 4.6e-11 42.9 0.0 6.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP67513.1 - 9.8e-06 25.5 0.1 1.7e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP67513.1 - 0.0017 18.5 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EJP67513.1 - 0.0018 18.5 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EJP67513.1 - 0.08 13.3 0.0 0.21 11.9 0.0 1.7 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein GST_C_4 PF14834.6 EJP67513.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.24 EJP67514.1 - 5.5e-90 302.4 13.4 7.8e-90 301.9 13.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP67514.1 - 7.3e-31 107.4 47.5 5.2e-27 94.7 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp_Glu_race PF01177.22 EJP67515.1 - 0.0042 17.0 0.0 0.016 15.1 0.0 1.8 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase CDC45 PF02724.14 EJP67515.1 - 0.023 13.0 0.0 0.033 12.5 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Actin PF00022.19 EJP67516.1 - 1.3e-112 376.4 0.0 7.7e-112 373.9 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EJP67516.1 - 0.02 13.7 0.0 0.22 10.3 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein Actin_micro PF17003.5 EJP67516.1 - 0.11 11.7 0.2 0.63 9.2 0.1 2.0 2 0 0 2 2 2 0 Putative actin-like family Pkinase PF00069.25 EJP67517.1 - 2.4e-60 204.2 0.0 8e-60 202.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67517.1 - 1.7e-29 102.9 0.0 2.5e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP67517.1 - 0.043 13.1 0.0 0.089 12.1 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EJP67517.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Arf PF00025.21 EJP67518.1 - 2.2e-72 242.2 0.2 2.5e-72 242.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EJP67518.1 - 2.7e-14 53.4 0.0 3.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJP67518.1 - 2e-13 50.2 0.0 2.3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EJP67518.1 - 1.7e-12 47.2 1.8 1.3e-08 34.4 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EJP67518.1 - 3.2e-11 43.1 0.0 3.8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EJP67518.1 - 1.9e-10 40.5 0.0 2.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EJP67518.1 - 0.00034 20.7 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SpoOE-like PF09388.10 EJP67518.1 - 0.016 15.1 1.1 0.027 14.4 1.1 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein 6PF2K PF01591.18 EJP67518.1 - 0.023 14.0 0.3 0.077 12.3 0.3 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 EJP67518.1 - 0.08 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 FUSC-like PF12805.7 EJP67518.1 - 0.22 10.6 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF1325 PF07039.11 EJP67519.1 - 1.2e-36 125.7 0.1 1.9e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF3104 PF11302.8 EJP67519.1 - 0.0085 15.8 0.0 0.069 12.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3104) DUF4426 PF14467.6 EJP67520.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4426) ChaB PF06150.12 EJP67520.1 - 0.11 13.1 1.4 0.24 12.0 0.2 2.1 2 0 0 2 2 2 0 ChaB Cir_N PF10197.9 EJP67521.1 - 7e-09 35.7 3.7 7e-09 35.7 3.7 3.6 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 EJP67521.1 - 0.5 11.3 9.4 1.9 9.4 5.1 2.8 2 1 0 2 2 2 0 Pre-mRNA splicing factor CAP_N PF01213.19 EJP67522.1 - 0.29 10.6 1.3 0.4 10.1 1.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAD_binding_4 PF01565.23 EJP67523.1 - 1.5e-25 89.6 2.9 2.7e-25 88.7 2.9 1.5 1 0 0 1 1 1 1 FAD binding domain SecY PF00344.20 EJP67524.1 - 2.9e-71 240.2 7.9 3.7e-71 239.9 7.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EJP67524.1 - 3.2e-17 62.1 0.2 1e-16 60.5 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p IPPT PF01715.17 EJP67525.1 - 3.7e-63 213.4 0.3 5.3e-63 212.9 0.3 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EJP67525.1 - 1.9e-05 24.2 0.0 0.00016 21.2 0.0 2.0 2 0 0 2 2 2 1 Isopentenyl transferase AAA_16 PF13191.6 EJP67525.1 - 0.00075 19.9 1.1 0.0028 18.0 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EJP67525.1 - 0.0045 17.1 4.2 0.021 15.0 0.3 3.1 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EJP67525.1 - 0.0099 15.6 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein CTU2 PF10288.9 EJP67525.1 - 0.015 15.5 0.3 0.034 14.4 0.0 1.7 2 0 0 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 AAA_18 PF13238.6 EJP67525.1 - 0.024 15.2 1.1 0.66 10.5 1.1 2.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EJP67525.1 - 0.048 13.9 1.2 0.44 10.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EJP67525.1 - 0.056 12.7 0.2 0.24 10.7 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin ABC_tran PF00005.27 EJP67525.1 - 0.057 13.9 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Hpr_kinase_C PF07475.12 EJP67525.1 - 0.068 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 EJP67525.1 - 0.082 13.2 0.1 1.1 9.5 0.0 2.7 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 EJP67525.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein zf-C2H2_4 PF13894.6 EJP67525.1 - 0.14 13.0 0.1 0.43 11.6 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Pkinase PF00069.25 EJP67526.1 - 0.00029 20.3 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Fungal_trans PF04082.18 EJP67527.1 - 6.4e-16 58.2 0.5 1.5e-15 56.9 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67527.1 - 1.6e-08 34.5 7.9 2.8e-08 33.7 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_hydroxylase PF04116.13 EJP67528.1 - 1e-20 74.4 8.9 1e-20 74.4 8.9 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_76 PF03663.14 EJP67529.1 - 7.2e-147 489.7 6.1 8.6e-147 489.4 6.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EJP67529.1 - 0.031 13.4 9.0 1.1 8.3 4.1 3.2 1 1 2 3 3 3 0 Glycosyl Hydrolase Family 88 DUF3602 PF12223.8 EJP67530.1 - 1.1e-12 48.4 7.7 2.9e-09 37.4 1.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Actin PF00022.19 EJP67531.1 - 5.9e-125 417.1 0.0 2.4e-124 415.1 0.0 1.7 1 1 0 1 1 1 1 Actin Ank_2 PF12796.7 EJP67532.1 - 1.8e-13 50.9 0.1 0.00011 22.7 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP67532.1 - 3.3e-10 40.3 0.9 0.0045 17.5 0.3 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EJP67532.1 - 6.8e-09 35.8 0.0 0.0029 18.0 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EJP67532.1 - 7.3e-09 35.7 1.3 0.022 15.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP67532.1 - 1.8e-08 34.0 0.1 0.023 15.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 EJP67532.1 - 6.4e-07 29.2 0.1 7.1e-06 25.8 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain Pkinase PF00069.25 EJP67535.1 - 5.1e-66 222.7 0.0 1e-65 221.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67535.1 - 2.9e-44 151.3 0.0 4.9e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP67535.1 - 4.1e-05 22.5 0.1 9.2e-05 21.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EJP67535.1 - 0.0056 16.0 0.0 0.063 12.6 0.1 2.1 2 0 0 2 2 2 1 Kinase-like Mur_ligase_M PF08245.12 EJP67537.1 - 2.3e-07 31.0 0.0 4.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain TFIIS_C PF01096.18 EJP67537.1 - 0.24 11.3 0.5 0.66 9.9 0.0 1.9 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Peptidase_S9 PF00326.21 EJP67538.1 - 2.5e-06 27.1 0.3 0.032 13.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EJP67538.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PhoPQ_related PF10142.9 EJP67538.1 - 0.068 11.8 0.2 0.1 11.2 0.2 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein ICE2 PF08426.10 EJP67539.1 - 4.6e-158 526.6 9.1 5.2e-158 526.4 9.1 1.0 1 0 0 1 1 1 1 ICE2 Aa_trans PF01490.18 EJP67541.1 - 5.8e-28 97.7 29.6 6.7e-28 97.5 29.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spo7 PF03907.13 EJP67541.1 - 0.094 12.2 0.3 0.27 10.7 0.3 1.7 1 0 0 1 1 1 0 Spo7-like protein PRT_C PF08372.10 EJP67541.1 - 0.33 10.7 1.7 6.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal FA_desaturase PF00487.24 EJP67542.1 - 5.3e-26 92.0 17.7 1.8e-25 90.2 15.9 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 EJP67542.1 - 3.7e-19 67.9 0.4 6.1e-19 67.2 0.4 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 EJP67543.1 - 2e-24 85.5 0.1 1.1e-23 83.2 0.0 2.0 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 EJP67543.1 - 0.0054 16.9 0.1 0.17 12.1 0.0 2.6 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 EJP67543.1 - 0.021 15.1 0.1 0.051 13.8 0.0 1.7 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase ALO PF04030.14 EJP67543.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase UBX PF00789.20 EJP67544.1 - 3.9e-06 27.0 1.9 4.2e-06 26.9 0.0 2.1 3 0 0 3 3 3 1 UBX domain UBA PF00627.31 EJP67544.1 - 0.0039 17.1 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 EJP67544.1 - 0.0087 16.1 0.1 0.0087 16.1 0.1 2.9 3 0 0 3 3 3 1 HOIP UBA domain pair DUF959 PF06121.14 EJP67544.1 - 0.019 15.2 2.7 0.036 14.3 2.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) zf-C2H2 PF00096.26 EJP67544.1 - 0.044 14.3 0.1 0.09 13.3 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type SOBP PF15279.6 EJP67544.1 - 0.58 10.7 7.7 0.68 10.5 7.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein zf-C2H2_3rep PF18868.1 EJP67544.1 - 1.4 9.6 5.2 1 10.1 0.1 2.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Ribosomal_60s PF00428.19 EJP67545.1 - 3.3e-29 101.3 8.7 3.9e-29 101.1 8.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.9 EJP67546.1 - 3.6e-37 127.9 2.5 3.6e-21 76.1 0.0 4.9 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 EJP67546.1 - 0.15 12.5 2.3 4.1 7.9 0.2 4.0 3 1 1 4 4 4 0 Snapin/Pallidin FapA PF03961.13 EJP67546.1 - 0.2 10.2 1.1 11 4.5 0.1 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF1539 PF07560.11 EJP67546.1 - 0.32 11.1 2.0 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Prefoldin_2 PF01920.20 EJP67546.1 - 2.4 8.1 6.0 22 5.0 0.0 4.1 4 0 0 4 4 4 0 Prefoldin subunit YCII PF03795.14 EJP67547.1 - 4.6e-09 36.6 0.0 3.6e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 YCII-related domain FlgM PF04316.13 EJP67547.1 - 0.031 14.6 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Fungal_trans_2 PF11951.8 EJP67548.1 - 7.3e-43 146.8 3.0 9.9e-43 146.4 3.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 EJP67549.1 - 7e-10 38.8 0.3 1.8e-05 24.3 0.3 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP67549.1 - 6.8e-07 29.4 5.1 9.6e-07 28.9 1.6 2.3 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EJP67549.1 - 1.5e-05 24.7 0.8 1.5e-05 24.7 0.8 1.8 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EJP67549.1 - 3e-05 24.3 0.3 8.6e-05 22.8 0.3 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EJP67549.1 - 9.3e-05 21.6 0.0 0.00037 19.6 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EJP67549.1 - 0.00022 20.5 0.2 0.00044 19.5 0.2 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EJP67549.1 - 0.00054 19.5 0.3 0.068 12.6 0.1 2.7 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EJP67549.1 - 0.0047 17.4 0.2 0.014 15.8 0.1 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EJP67549.1 - 0.0054 15.9 1.0 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Ldh_1_N PF00056.23 EJP67549.1 - 0.083 13.0 0.2 0.21 11.7 0.2 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EJP67549.1 - 0.11 13.4 0.8 0.95 10.3 0.1 2.6 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold PMI_typeI PF01238.21 EJP67550.1 - 4.5e-59 200.5 0.0 1.4e-58 198.9 0.0 1.8 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EJP67550.1 - 1.4e-05 24.7 0.0 0.004 16.9 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.7 EJP67550.1 - 0.027 14.2 0.4 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Cupin Ectoine_synth PF06339.12 EJP67550.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Ectoine synthase AraC_binding PF02311.19 EJP67550.1 - 0.13 12.2 0.1 2.3 8.1 0.0 2.5 3 0 0 3 3 3 0 AraC-like ligand binding domain Cupin_3 PF05899.12 EJP67550.1 - 0.19 11.4 0.0 0.46 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF676 PF05057.14 EJP67551.1 - 1.1e-50 172.2 0.1 2e-50 171.3 0.0 1.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EJP67551.1 - 5.7e-05 22.9 0.1 0.0024 17.6 0.0 2.7 2 1 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 EJP67551.1 - 0.00013 21.9 0.0 0.00034 20.5 0.0 1.7 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 EJP67551.1 - 0.00021 22.0 0.1 0.002 18.8 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EJP67551.1 - 0.066 13.1 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) GCIP PF13324.6 EJP67551.1 - 0.088 12.4 0.6 0.12 11.9 0.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PRELI PF04707.14 EJP67552.1 - 4.5e-20 72.0 0.1 4.9e-17 62.2 0.0 2.1 1 1 1 2 2 2 2 PRELI-like family LMWPc PF01451.21 EJP67553.1 - 1.3e-40 139.0 0.0 1.5e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.25 EJP67554.1 - 7.1e-69 232.1 0.0 9.1e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67554.1 - 3.7e-31 108.3 0.0 5.5e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJP67554.1 - 0.0064 15.5 0.0 0.022 13.7 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EJP67554.1 - 0.039 13.9 0.1 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EJP67554.1 - 0.051 12.9 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IRK PF01007.20 EJP67554.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain DUF3455 PF11937.8 EJP67555.1 - 1e-30 107.2 0.0 1.5e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Hexapep PF00132.24 EJP67557.1 - 7.3e-12 44.5 3.6 7.5e-06 25.5 0.3 4.6 3 2 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EJP67557.1 - 3.4e-05 23.5 0.9 0.0018 18.0 0.3 3.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EJP67557.1 - 0.16 10.9 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Syntaphilin PF15290.6 EJP67557.1 - 0.28 10.8 0.7 0.38 10.4 0.7 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Bys1 PF04681.12 EJP67558.1 - 8.5e-16 58.3 0.0 1e-15 58.0 0.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein GST_C PF00043.25 EJP67559.1 - 5.1e-14 52.3 0.0 8.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EJP67559.1 - 1.3e-12 47.8 0.0 2.4e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EJP67559.1 - 1.6e-11 44.4 0.0 2.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EJP67559.1 - 7e-09 35.8 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EJP67559.1 - 5.5e-08 33.0 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP67559.1 - 1.4e-06 28.2 0.1 2.9e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PMI_typeI PF01238.21 EJP67560.1 - 1.9e-133 445.3 0.0 2.2e-133 445.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EJP67560.1 - 0.14 12.1 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain Pro_isomerase PF00160.21 EJP67562.1 - 8.4e-35 120.4 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EJP67562.1 - 1.5e-14 53.6 0.0 2.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FliT PF05400.13 EJP67563.1 - 0.0011 19.8 3.7 0.0081 16.9 1.8 2.2 2 0 0 2 2 2 1 Flagellar protein FliT PNISR PF15996.5 EJP67563.1 - 0.032 14.5 0.3 0.046 14.0 0.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF3199 PF11436.8 EJP67563.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) Methyltransf_16 PF10294.9 EJP67564.1 - 1.8e-20 73.4 0.0 2.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EJP67564.1 - 0.00028 21.5 0.0 0.0006 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP67564.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EJP67564.1 - 0.016 15.9 0.0 0.03 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EJP67564.1 - 0.019 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EJP67564.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EJP67564.1 - 0.034 14.0 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 EJP67564.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Met_10 PF02475.16 EJP67564.1 - 0.05 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 EJP67564.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S24e PF01282.19 EJP67565.1 - 1.4e-31 108.2 0.0 2.8e-31 107.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e GTP_cyclohydro2 PF00925.20 EJP67568.1 - 8.9e-61 204.2 0.0 1.2e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II RPA43_OB PF17875.1 EJP67569.1 - 2.7e-34 118.4 0.1 2.7e-34 118.4 0.1 4.2 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I FHA PF00498.26 EJP67570.1 - 7e-05 23.1 0.1 0.00016 21.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain Ala_racemase_C PF00842.21 EJP67570.1 - 0.03 14.1 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain NDUF_B7 PF05676.13 EJP67571.1 - 6e-29 99.6 6.3 7.1e-29 99.3 6.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EJP67571.1 - 0.00026 21.0 2.5 0.00026 21.0 2.5 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Aa_trans PF01490.18 EJP67572.1 - 3.4e-35 121.6 28.7 3.9e-35 121.3 28.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LapA_dom PF06305.11 EJP67572.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.7 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pox_I5 PF04713.12 EJP67572.1 - 0.58 10.2 7.2 0.99 9.5 0.1 3.4 3 0 0 3 3 3 0 Poxvirus protein I5 Ank_5 PF13857.6 EJP67575.1 - 5.8e-37 125.3 7.5 4.6e-10 39.6 0.1 6.1 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP67575.1 - 3.1e-35 120.6 8.5 8.8e-12 45.5 0.3 3.9 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP67575.1 - 5.5e-30 103.4 4.5 1.2e-09 38.5 0.1 6.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EJP67575.1 - 6.4e-30 102.3 7.3 0.00024 21.4 0.0 6.7 6 1 1 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EJP67575.1 - 3.7e-26 88.3 2.3 0.00073 19.8 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat RelA_SpoT PF04607.17 EJP67575.1 - 2.7e-08 34.1 0.0 2.3e-07 31.1 0.0 2.4 2 1 0 2 2 2 1 Region found in RelA / SpoT proteins DUF3447 PF11929.8 EJP67575.1 - 0.00018 21.4 0.0 0.58 10.2 0.0 4.3 2 1 1 4 4 4 1 Domain of unknown function (DUF3447) MDMPI_C PF07398.11 EJP67575.1 - 0.13 13.1 0.9 0.47 11.4 0.9 2.0 1 1 0 1 1 1 0 MDMPI C-terminal domain NUDIX PF00293.28 EJP67576.1 - 7.5e-13 48.7 0.1 1e-12 48.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain OB_NTP_bind PF07717.16 EJP67578.1 - 1.3e-20 73.5 0.0 3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EJP67578.1 - 3.4e-17 62.7 0.0 3.4e-17 62.7 0.0 3.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EJP67578.1 - 5.2e-15 55.7 0.0 1.6e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EJP67578.1 - 2.1e-06 28.1 0.0 7.1e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EJP67578.1 - 7.6e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EJP67578.1 - 0.00075 19.3 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EJP67578.1 - 0.0038 16.3 0.0 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EJP67578.1 - 0.0055 17.0 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EJP67578.1 - 0.034 13.8 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EJP67578.1 - 0.049 14.2 0.0 0.18 12.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 EJP67578.1 - 0.13 11.9 0.3 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EJP67578.1 - 0.69 9.9 2.7 9.7 6.2 0.2 3.3 2 1 0 2 2 2 0 AAA domain NIF PF03031.18 EJP67579.1 - 5e-56 188.8 0.0 7.4e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1761 PF08570.10 EJP67580.1 - 1.4e-24 86.7 4.1 1.6e-24 86.5 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Ribosomal_L7Ae PF01248.26 EJP67581.1 - 2.2e-21 75.4 0.3 2.2e-21 75.4 0.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UcrQ PF02939.16 EJP67582.1 - 7e-33 112.4 0.4 8.2e-33 112.2 0.4 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 EJP67583.1 - 1.2e-23 84.0 9.8 2.7e-23 82.9 9.8 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EJP67583.1 - 0.0055 15.8 6.3 0.0071 15.4 6.3 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF2073 PF09846.9 EJP67584.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) Pkinase PF00069.25 EJP67585.1 - 9.1e-24 84.2 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67585.1 - 2.4e-11 43.4 0.0 3.1e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP67585.1 - 1.4e-06 27.4 0.0 1.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EJP67585.1 - 4.6e-05 23.5 0.0 0.014 15.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EJP67585.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Amidohydro_2 PF04909.14 EJP67587.1 - 6.5e-07 29.4 0.0 1.6e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EJP67587.1 - 0.0022 17.4 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.6 EJP67587.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain AA_permease PF00324.21 EJP67588.1 - 4e-122 408.2 40.9 5e-122 407.9 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP67588.1 - 5.6e-39 134.2 42.0 7e-39 133.9 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease TRP PF06011.12 EJP67589.1 - 1.6e-155 518.0 28.2 2e-155 517.7 28.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EJP67589.1 - 1e-31 110.2 0.2 1.6e-31 109.5 0.2 1.3 1 0 0 1 1 1 1 ML-like domain FCH PF00611.23 EJP67590.1 - 3.4e-25 88.1 0.5 1.2e-24 86.4 0.2 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EJP67590.1 - 8.9e-21 73.5 2.0 6.6e-11 41.9 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EJP67590.1 - 1.1e-15 56.9 0.2 3.9e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 EJP67590.1 - 5.8e-15 54.9 5.2 9.2e-15 54.3 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_10 PF17902.1 EJP67590.1 - 3.3e-05 23.9 0.1 0.049 13.7 0.0 3.6 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.17 EJP67590.1 - 0.0016 18.0 0.1 2.7 7.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 EJP67590.1 - 0.0095 16.2 0.9 0.55 10.5 0.2 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain C1_2 PF03107.16 EJP67590.1 - 0.011 16.1 5.0 0.02 15.2 5.0 1.4 1 0 0 1 1 1 0 C1 domain Allexi_40kDa PF05549.11 EJP67590.1 - 0.053 13.0 3.7 0.054 13.0 0.1 2.4 2 1 0 2 2 2 0 Allexivirus 40kDa protein FYVE PF01363.21 EJP67590.1 - 0.095 12.8 2.2 0.21 11.7 2.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C2H2 PF00096.26 EJP67591.1 - 4.1e-07 30.1 12.2 0.027 14.9 1.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP67591.1 - 0.003 18.3 8.1 2.8 9.0 0.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger MAD PF05557.13 EJP67591.1 - 0.0058 15.1 1.1 0.0078 14.6 1.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Cwf_Cwc_15 PF04889.12 EJP67591.1 - 0.0066 16.2 2.5 0.01 15.6 2.5 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-C2H2_aberr PF17017.5 EJP67591.1 - 0.011 15.9 2.1 0.28 11.3 0.1 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger ZapB PF06005.12 EJP67591.1 - 0.063 13.7 1.8 0.15 12.5 1.8 1.6 1 0 0 1 1 1 0 Cell division protein ZapB HAUS5 PF14817.6 EJP67591.1 - 0.066 12.0 3.9 0.089 11.5 3.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 ICAP-1_inte_bdg PF10480.9 EJP67591.1 - 0.089 12.8 0.4 0.13 12.2 0.4 1.2 1 0 0 1 1 1 0 Beta-1 integrin binding protein zf-C2H2_6 PF13912.6 EJP67591.1 - 0.098 12.7 0.5 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger IBR PF01485.21 EJP67591.1 - 0.12 12.6 3.4 3.6 7.9 0.0 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DUF3450 PF11932.8 EJP67591.1 - 0.16 11.2 3.5 0.23 10.7 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-H2C2_2 PF13465.6 EJP67591.1 - 0.48 10.9 16.9 4.1 8.0 3.9 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 EJP67591.1 - 1.9 8.3 8.4 0.91 9.3 0.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DivIC PF04977.15 EJP67591.1 - 2.4 8.0 5.9 1.6 8.5 3.0 2.1 2 1 0 2 2 2 0 Septum formation initiator Dynamin_N PF00350.23 EJP67592.1 - 6.2e-34 117.5 0.1 1.1e-33 116.7 0.1 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EJP67592.1 - 6.2e-17 61.7 0.0 7.6e-16 58.2 0.0 2.5 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EJP67592.1 - 0.00017 21.6 0.2 0.012 15.7 0.2 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EJP67592.1 - 0.016 14.5 1.0 0.59 9.4 0.1 2.5 1 1 1 2 2 2 0 AIG1 family GED PF02212.18 EJP67592.1 - 0.029 14.5 0.3 0.18 12.0 0.3 2.5 1 1 0 1 1 1 0 Dynamin GTPase effector domain Ank_2 PF12796.7 EJP67593.1 - 1.4e-55 185.8 0.1 5.5e-16 58.9 0.0 6.1 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP67593.1 - 1.7e-38 130.5 1.9 2.9e-07 30.9 0.0 7.7 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP67593.1 - 1.2e-36 120.6 1.1 0.0099 16.3 0.1 11.2 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 EJP67593.1 - 4.7e-32 109.6 4.9 2.5e-08 34.0 0.1 7.4 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EJP67593.1 - 2e-31 107.0 6.4 0.00012 22.3 0.2 11.0 10 1 1 11 11 11 7 Ankyrin repeat HET PF06985.11 EJP67593.1 - 4e-08 33.7 1.7 6.1e-07 29.9 0.2 2.6 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Acetyltransf_1 PF00583.25 EJP67593.1 - 0.0011 19.2 0.0 0.008 16.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 EJP67593.1 - 0.0036 17.2 0.4 0.045 13.7 0.0 2.8 3 0 0 3 3 3 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 EJP67593.1 - 0.0057 17.1 0.0 0.081 13.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP67593.1 - 0.11 12.4 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain VWA_3_C PF18571.1 EJP67593.1 - 2.8 7.9 8.5 19 5.2 0.7 5.1 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain MFS_1 PF07690.16 EJP67594.1 - 2e-30 105.9 36.0 2e-30 105.9 36.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CSG2 PF16965.5 EJP67594.1 - 0.064 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator UNC-93 PF05978.16 EJP67594.1 - 0.78 9.4 6.7 0.26 11.0 3.2 2.0 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 GDPD PF03009.17 EJP67595.1 - 1.5e-36 126.5 0.0 2.3e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EJP67595.1 - 2.4e-17 63.3 0.0 1.7e-10 41.4 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP67595.1 - 6.1e-10 39.4 0.0 8.1e-05 23.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP67595.1 - 3e-08 33.7 0.0 0.00079 19.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP67595.1 - 1.9e-06 27.7 0.0 0.0057 17.1 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EJP67595.1 - 7.4e-06 26.2 0.0 0.00044 20.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat SPX PF03105.19 EJP67595.1 - 9.1e-06 25.8 0.3 1.6e-05 25.0 0.3 1.5 1 1 0 1 1 1 1 SPX domain DUF5127 PF17168.4 EJP67596.1 - 8.1e-85 284.2 0.8 1.2e-84 283.7 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EJP67596.1 - 3.6e-74 248.1 0.0 6.4e-74 247.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EJP67596.1 - 2.9e-60 203.5 2.6 4.6e-60 202.8 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EJP67596.1 - 4.8e-08 32.5 2.0 2.5e-07 30.1 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 EJP67596.1 - 0.00018 21.1 0.1 0.00041 19.9 0.1 1.6 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF4841 PF16129.5 EJP67597.1 - 0.046 14.0 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) Pkinase PF00069.25 EJP67598.1 - 1.5e-07 31.1 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67598.1 - 7.7e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP67598.1 - 0.015 15.3 0.2 0.015 15.3 0.2 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EJP67598.1 - 0.056 12.2 0.9 0.078 11.7 0.1 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EJP67598.1 - 0.095 12.0 0.0 0.98 8.7 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EJP67598.1 - 0.14 11.7 0.4 0.27 10.8 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex14_N PF04695.13 EJP67599.1 - 0.71 10.5 3.9 4.5 7.9 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MRP-L20 PF12824.7 EJP67600.1 - 9e-47 159.3 4.3 1.1e-46 159.0 4.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 EJP67600.1 - 0.024 14.7 0.2 0.035 14.1 0.2 1.4 1 0 0 1 1 1 0 Neugrin Fe-ADH PF00465.19 EJP67602.1 - 1.3e-101 340.0 0.0 1.7e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EJP67602.1 - 1.7e-13 50.9 0.0 1.8e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Hexapep PF00132.24 EJP67603.1 - 9.4e-13 47.3 9.8 4.4e-08 32.5 0.4 3.9 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EJP67603.1 - 1.1e-06 28.3 8.5 0.061 13.1 0.0 4.2 3 1 1 5 5 5 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EJP67603.1 - 0.027 13.4 0.2 0.11 11.3 0.0 1.7 1 1 1 2 2 2 0 L-fucokinase Complex1_51K PF01512.17 EJP67604.1 - 4.4e-47 159.8 0.0 6.9e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EJP67604.1 - 3.5e-29 100.7 1.5 4.6e-29 100.3 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EJP67604.1 - 2.6e-09 36.8 0.0 1.5e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 SLBB domain PEX11 PF05648.14 EJP67605.1 - 1.3e-16 60.8 0.0 3.5e-15 56.1 0.0 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF5596 PF18082.1 EJP67605.1 - 0.012 15.4 1.3 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) PTPRCAP PF15713.5 EJP67605.1 - 0.025 14.9 2.5 0.041 14.2 2.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Spt5_N PF11942.8 EJP67605.1 - 0.08 13.9 7.1 0.12 13.4 7.1 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Coilin_N PF15862.5 EJP67605.1 - 4.6 7.0 7.9 1.5 8.6 5.3 1.4 2 0 0 2 2 2 0 Coilin N-terminus Med19 PF10278.9 EJP67605.1 - 5.5 6.9 11.5 8.9 6.2 11.5 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.14 EJP67605.1 - 8.1 4.6 6.4 11 4.2 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Smr PF01713.21 EJP67606.1 - 0.00019 21.8 0.1 0.00069 19.9 0.1 2.0 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 EJP67606.1 - 0.00029 20.4 0.1 0.00067 19.3 0.1 1.6 1 0 0 1 1 1 1 CUE domain DUF1771 PF08590.10 EJP67606.1 - 0.0063 16.9 12.0 0.0063 16.9 12.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) RAP1 PF07218.11 EJP67606.1 - 0.015 13.6 1.8 0.022 13.1 1.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NPC1_N PF16414.5 EJP67607.1 - 9e-81 271.0 6.1 1.3e-80 270.5 6.1 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EJP67607.1 - 3.1e-73 247.2 11.5 1.2e-45 155.9 0.1 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EJP67607.1 - 1e-49 168.3 3.6 1e-49 168.3 3.6 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EJP67607.1 - 7.1e-05 21.9 8.7 7.1e-05 21.9 8.7 3.0 2 1 0 2 2 2 1 MMPL family Mannosyl_trans2 PF04188.13 EJP67608.1 - 5.1e-51 174.4 0.4 1.2e-50 173.2 0.4 1.6 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) tRNA_bind_3 PF17176.4 EJP67608.1 - 0.033 14.5 0.9 0.075 13.3 0.4 1.8 2 0 0 2 2 2 0 tRNA-binding domain DUF1604 PF07713.13 EJP67609.1 - 3.8e-39 132.4 1.3 3.8e-39 132.4 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EJP67609.1 - 8.6e-06 25.6 1.0 4e-05 23.4 0.7 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EJP67609.1 - 8.7e-05 22.5 0.1 0.00031 20.8 0.1 2.0 1 0 0 1 1 1 1 G-patch domain Pkinase PF00069.25 EJP67610.1 - 5.4e-69 232.5 0.0 1e-68 231.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67610.1 - 7e-40 136.9 0.0 2.1e-39 135.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EJP67610.1 - 2.8e-20 71.8 0.2 5.2e-20 71.0 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 EJP67610.1 - 3.1e-07 29.7 0.0 3.1e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EJP67610.1 - 3.5e-05 23.2 0.1 7.5e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJP67610.1 - 0.00014 21.3 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJP67610.1 - 0.01 15.8 1.6 0.015 15.2 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 EJP67610.1 - 0.026 14.1 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EJP67610.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Rcd1 PF04078.13 EJP67611.1 - 2.9e-125 416.8 4.6 4.9e-125 416.0 4.6 1.3 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.13 EJP67611.1 - 0.00088 19.4 37.9 0.0011 19.0 37.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EJP67611.1 - 0.0081 14.5 30.4 0.011 14.1 30.4 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 EJP67611.1 - 0.042 14.0 7.7 0.077 13.1 7.7 1.5 1 0 0 1 1 1 0 DDHD domain LAP1C PF05609.12 EJP67611.1 - 0.098 11.7 14.0 0.13 11.3 14.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Otopetrin PF03189.13 EJP67611.1 - 0.15 10.8 4.1 0.29 9.9 4.1 1.4 1 0 0 1 1 1 0 Otopetrin Ndc1_Nup PF09531.10 EJP67611.1 - 0.3 9.7 9.8 0.41 9.3 9.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.8 EJP67611.1 - 0.55 9.0 11.1 0.79 8.5 11.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter eIF-3_zeta PF05091.12 EJP67611.1 - 0.64 8.9 18.2 0.88 8.5 18.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MMR1 PF08505.10 EJP67611.1 - 1.4 9.2 19.6 2 8.6 19.6 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SLC12 PF03522.15 EJP67611.1 - 1.6 7.6 15.5 2.3 7.1 15.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 BORG_CEP PF14957.6 EJP67611.1 - 2.4 9.3 7.5 4.4 8.5 7.5 1.5 1 0 0 1 1 1 0 Cdc42 effector DUF4638 PF15472.6 EJP67611.1 - 4 7.1 13.0 7 6.3 13.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PepSY_TM PF03929.16 EJP67611.1 - 6.6 6.3 10.6 10 5.7 10.6 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Suf PF05843.14 EJP67611.1 - 7.8 6.4 17.3 13 5.6 17.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM60A PF15396.6 EJP67611.1 - 8.4 6.3 11.3 16 5.5 11.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF1295 PF06966.12 EJP67612.1 - 2e-39 135.5 1.5 7.4e-38 130.4 1.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EJP67612.1 - 0.0057 17.0 0.7 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 EJP67612.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase bZIP_1 PF00170.21 EJP67613.1 - 0.0014 18.7 7.7 0.0025 17.9 7.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EJP67613.1 - 0.0092 16.0 7.3 0.014 15.5 7.3 1.2 1 0 0 1 1 1 1 Basic region leucine zipper Acetate_kinase PF00871.17 EJP67613.1 - 0.053 12.2 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetokinase family MGC-24 PF05283.11 EJP67613.1 - 6.2 7.3 7.5 1.9 9.0 4.2 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FBPase PF00316.20 EJP67614.1 - 5.6e-70 234.7 0.1 7.4e-70 234.3 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain PEX11 PF05648.14 EJP67615.1 - 2e-68 230.2 0.2 2.3e-68 230.0 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PXA PF02194.15 EJP67616.1 - 6.1e-48 163.2 0.6 6.1e-48 163.2 0.6 2.8 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 EJP67616.1 - 1.1e-27 96.8 0.1 3.5e-27 95.2 0.1 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EJP67616.1 - 3.3e-20 72.2 0.1 7.5e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EJP67616.1 - 2.1e-11 44.1 0.1 6.7e-11 42.5 0.1 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pyridoxal_deC PF00282.19 EJP67618.1 - 2.8e-21 75.7 0.0 3e-13 49.2 0.0 3.1 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain TAT_ubiq PF07706.12 EJP67618.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase ubiquitination site Zn_clus PF00172.18 EJP67619.1 - 1.1e-08 35.0 11.8 2.4e-08 34.0 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EJP67620.1 - 6.6e-30 104.2 0.0 9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_4 PF02390.17 EJP67621.1 - 2.5e-52 176.8 0.0 3.1e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EJP67621.1 - 0.00036 21.2 0.0 0.0014 19.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP67621.1 - 0.00065 20.4 0.0 0.0018 19.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP67621.1 - 0.0064 16.1 0.0 0.018 14.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EJP67621.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EJP67621.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glycos_transf_2 PF00535.26 EJP67621.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Methyltransf_23 PF13489.6 EJP67621.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67621.1 - 0.18 12.5 0.1 0.79 10.4 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Homoserine_dh PF00742.19 EJP67622.1 - 3e-52 177.0 0.0 4e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EJP67622.1 - 9.8e-17 61.7 0.0 1.7e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.21 EJP67622.1 - 0.014 14.6 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Thioredoxin PF00085.20 EJP67623.1 - 2.7e-20 72.3 0.1 5.7e-20 71.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EJP67623.1 - 2.6e-07 31.1 0.2 7.2e-07 29.6 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EJP67623.1 - 0.00088 19.4 0.0 0.0027 17.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EJP67623.1 - 0.0022 17.8 0.1 0.025 14.4 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EJP67623.1 - 0.0025 17.2 0.1 0.0034 16.8 0.1 1.2 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EJP67623.1 - 0.015 15.6 0.2 5.3 7.4 0.0 2.2 1 1 0 2 2 2 0 Thioredoxin-like HyaE PF07449.11 EJP67623.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE MFS_1 PF07690.16 EJP67624.1 - 5.6e-35 120.9 33.9 5.6e-35 120.9 33.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP67624.1 - 1.6e-05 24.0 9.8 1.6e-05 24.0 9.8 3.3 4 1 0 4 4 4 1 Sugar (and other) transporter Fungal_trans PF04082.18 EJP67625.1 - 9.5e-16 57.6 0.1 1.6e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67625.1 - 4.9e-09 36.2 9.0 1.1e-08 35.1 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4078 PF13300.6 EJP67626.1 - 2.1e-29 101.6 20.6 2.1e-29 101.6 20.6 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF4078) APG6_N PF17675.1 EJP67626.1 - 0.016 15.7 6.2 0.016 15.7 6.2 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region Vac7 PF12751.7 EJP67627.1 - 2.1e-159 531.0 7.8 2.1e-159 531.0 7.8 2.0 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 DUF2721 PF11026.8 EJP67627.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) ABC_membrane PF00664.23 EJP67628.1 - 1e-24 87.6 6.0 2.1e-24 86.7 6.0 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EJP67628.1 - 4.9e-23 82.2 0.0 3e-11 44.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP67628.1 - 1.1e-09 38.0 0.1 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Med22 PF06179.12 EJP67628.1 - 0.2 11.9 1.8 0.77 10.0 0.3 2.3 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex p450 PF00067.22 EJP67629.1 - 1.3e-16 60.4 0.0 5.9e-16 58.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF3445 PF11927.8 EJP67629.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) ERG4_ERG24 PF01222.17 EJP67630.1 - 8.9e-06 24.7 0.4 1e-05 24.5 0.4 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3325 PF11804.8 EJP67630.1 - 1.9 8.7 13.0 1.5e+02 2.6 11.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) zf-TRAF_2 PF15965.5 EJP67632.1 - 0.27 11.7 15.0 8.6 6.9 0.2 3.7 4 0 0 4 4 4 0 TRAF-like zinc-finger CCDC14 PF15254.6 EJP67632.1 - 1.4 7.5 2.4 1.9 7.1 2.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 RrnaAD PF00398.20 EJP67633.1 - 8.7e-64 215.1 0.0 1.1e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EJP67633.1 - 1.1e-06 29.2 0.0 2.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67633.1 - 0.00011 22.7 0.0 0.00027 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP67633.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EJP67633.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EJP67633.1 - 0.003 18.3 0.0 0.0085 16.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EJP67633.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EJP67633.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_lid_4 PF17864.1 EJP67633.1 - 0.02 14.6 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 RuvB AAA lid domain Methyltransf_2 PF00891.18 EJP67633.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PRP1_N PF06424.12 EJP67634.1 - 4.7e-49 166.6 8.2 1.3e-48 165.2 8.2 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EJP67634.1 - 9.2e-29 97.7 40.2 0.00063 20.3 0.0 14.2 5 3 10 15 15 15 11 Tetratricopeptide repeat TPR_19 PF14559.6 EJP67634.1 - 2.1e-27 95.4 20.4 1.3e-07 32.0 0.0 10.6 7 3 3 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 EJP67634.1 - 7.9e-11 41.2 15.5 0.74 10.1 0.0 11.0 12 1 1 13 13 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJP67634.1 - 1.2e-10 41.9 25.6 0.00044 20.8 0.3 8.4 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJP67634.1 - 4.1e-10 39.3 11.4 7.5 7.2 0.0 10.3 10 1 1 11 11 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP67634.1 - 1.3e-07 31.3 11.0 0.054 13.7 0.0 8.4 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJP67634.1 - 0.00019 21.5 18.9 0.029 14.5 0.1 6.6 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJP67634.1 - 0.00021 21.0 2.7 0.7 9.8 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EJP67634.1 - 0.00033 21.1 5.8 52 4.8 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 EJP67634.1 - 0.0004 20.0 7.6 0.24 11.1 0.0 6.1 7 1 1 8 8 8 2 TPR repeat NARP1 PF12569.8 EJP67634.1 - 0.00043 19.3 4.3 2.2 7.1 0.0 5.5 4 1 2 6 6 6 1 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 EJP67634.1 - 0.00071 19.3 13.9 0.2 11.3 1.2 4.7 3 1 1 5 5 5 3 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 EJP67634.1 - 0.00093 19.2 2.2 0.59 10.0 0.1 3.9 3 1 2 5 5 5 1 Virulence factor membrane-bound polymerase, C-terminal Suf PF05843.14 EJP67634.1 - 0.0043 17.1 0.2 8.8 6.2 0.0 4.2 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) DUF3808 PF10300.9 EJP67634.1 - 0.081 11.7 0.3 2.3 6.8 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3808) TPR_7 PF13176.6 EJP67634.1 - 0.35 11.0 5.7 3.6 7.8 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EJP67634.1 - 0.63 10.4 0.0 0.63 10.4 0.0 6.4 7 1 2 9 9 8 0 Tetratricopeptide repeat MADF_DNA_bdg PF10545.9 EJP67634.1 - 1.6 9.1 7.8 4.6 7.6 0.2 2.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like V-ATPase_G PF03179.15 EJP67635.1 - 0.033 14.7 4.6 0.033 14.7 4.6 2.0 2 1 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit Phasin PF05597.11 EJP67635.1 - 0.04 13.9 4.7 0.053 13.5 3.8 1.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 EJP67635.1 - 0.042 13.7 3.2 0.086 12.7 3.3 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain SH3BP5 PF05276.14 EJP67635.1 - 0.31 10.8 6.5 0.36 10.6 3.1 1.9 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) CDPS PF16715.5 EJP67635.1 - 0.49 10.0 5.6 8.3 6.0 0.2 2.1 1 1 1 2 2 2 0 Cyclodipeptide synthase V-ATPase_G_2 PF16999.5 EJP67635.1 - 1 9.8 13.2 0.42 11.1 2.7 2.6 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ISG65-75 PF11727.8 EJP67635.1 - 1.4 8.1 11.4 0.83 8.8 7.8 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein ATP-synt_B PF00430.18 EJP67635.1 - 2.7 8.1 12.5 1.7 8.7 9.4 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) RRF PF01765.19 EJP67635.1 - 3.5 7.6 6.3 7.7 6.4 4.8 1.8 1 1 1 2 2 2 0 Ribosome recycling factor ETRAMP PF09716.10 EJP67635.1 - 4.9 7.3 7.9 32 4.7 0.2 2.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF883 PF05957.13 EJP67635.1 - 6.7 7.4 16.2 0.31 11.7 7.5 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) PsbQ PF05757.11 EJP67636.1 - 0.11 12.2 1.0 0.13 12.0 1.0 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Rad10 PF03834.14 EJP67637.1 - 3.6e-48 162.3 0.0 5e-48 161.9 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) MR_MLE_C PF13378.6 EJP67638.1 - 2.9e-55 187.2 0.0 5.6e-55 186.3 0.0 1.4 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EJP67638.1 - 0.0024 18.1 0.1 0.0052 17.0 0.1 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EJP67638.1 - 0.0058 15.8 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus AcrZ PF10766.9 EJP67639.1 - 0.35 10.5 1.3 0.46 10.1 1.3 1.2 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ zf-CGNR PF11706.8 EJP67640.1 - 0.029 14.2 0.1 0.089 12.7 0.1 1.8 1 0 0 1 1 1 0 CGNR zinc finger GSDH PF07995.11 EJP67641.1 - 0.00066 19.1 1.7 0.031 13.6 0.1 2.8 3 1 0 3 3 3 2 Glucose / Sorbosone dehydrogenase SGL PF08450.12 EJP67641.1 - 0.0094 15.6 0.8 1.2 8.6 0.1 3.0 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region RCC1_2 PF13540.6 EJP67641.1 - 0.031 14.1 0.8 6.3 6.7 0.0 3.0 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Reg_prop PF07494.11 EJP67641.1 - 0.035 14.3 0.0 2.6 8.6 0.0 3.7 3 0 0 3 3 3 0 Two component regulator propeller NHL PF01436.21 EJP67641.1 - 0.1 12.7 0.0 4.3 7.6 0.0 3.6 4 0 0 4 4 4 0 NHL repeat WD40 PF00400.32 EJP67642.1 - 2.9e-24 84.9 16.9 7.8e-06 26.5 0.1 6.9 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP67642.1 - 9e-12 45.1 3.2 0.0029 17.8 0.0 4.6 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EJP67642.1 - 0.0034 17.3 6.0 1.7 8.5 2.2 3.7 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term G_path_suppress PF15991.5 EJP67643.1 - 8.2 6.5 12.2 5.7 7.0 10.8 1.4 1 1 0 1 1 1 0 G-protein pathway suppressor BCS1_N PF08740.11 EJP67646.1 - 1.7e-53 181.4 0.3 1.7e-53 181.4 0.3 2.3 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EJP67646.1 - 7.3e-20 71.7 0.0 1.4e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJP67646.1 - 0.0003 21.2 0.0 0.00076 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EJP67646.1 - 0.0017 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EJP67646.1 - 0.0022 17.6 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EJP67646.1 - 0.0024 17.8 0.1 0.0094 16.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EJP67646.1 - 0.038 14.5 0.0 0.038 14.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EJP67646.1 - 0.042 13.9 0.7 0.076 13.1 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SAPS PF04499.15 EJP67646.1 - 0.068 11.9 6.0 0.088 11.6 6.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_11 PF13086.6 EJP67646.1 - 0.1 12.3 14.8 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EJP67646.1 - 0.11 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4746 PF15928.5 EJP67646.1 - 0.99 8.8 19.3 1.6 8.1 19.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDHD PF02862.17 EJP67646.1 - 3.8 7.6 8.0 13 5.9 7.9 1.9 2 0 0 2 2 2 0 DDHD domain FAD_binding_2 PF00890.24 EJP67647.1 - 1.1e-40 140.0 1.5 4.7e-40 138.0 1.5 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJP67647.1 - 3.2e-07 30.3 1.4 3.2e-07 30.3 1.4 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EJP67647.1 - 5.7e-07 29.1 6.6 0.0064 15.8 0.0 3.6 3 1 1 4 4 4 2 FAD binding domain Pyr_redox_2 PF07992.14 EJP67647.1 - 1.1e-06 28.2 0.2 5.8e-05 22.5 0.3 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EJP67647.1 - 3.5e-06 26.6 0.3 5.4e-06 26.0 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP67647.1 - 1.5e-05 23.9 3.5 0.019 13.7 0.1 3.2 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 EJP67647.1 - 0.002 17.3 0.3 0.0086 15.2 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EJP67647.1 - 0.08 12.2 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EJP67647.1 - 0.088 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HMG_CoA_synt_C PF08540.10 EJP67648.1 - 3e-106 355.1 0.6 3.8e-106 354.8 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EJP67648.1 - 3.1e-95 317.0 0.5 4.8e-95 316.4 0.5 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal FAD_binding_4 PF01565.23 EJP67649.1 - 1.2e-14 54.3 0.0 2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_3 PF07859.13 EJP67651.1 - 5e-36 124.6 0.1 1.9e-35 122.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP67651.1 - 7.7e-06 25.0 0.0 0.0028 16.6 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Pex14_N PF04695.13 EJP67652.1 - 1e-33 117.2 8.6 1e-33 117.2 8.6 3.7 2 2 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.9 EJP67652.1 - 0.00082 19.7 3.4 0.00082 19.7 3.4 2.2 2 0 0 2 2 2 1 Zinc finger-containing protein HLH PF00010.26 EJP67652.1 - 0.0015 18.4 0.1 12 5.9 0.4 3.3 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain CR6_interact PF10147.9 EJP67652.1 - 0.0033 17.2 1.3 0.0053 16.5 1.3 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1043 PF06295.12 EJP67652.1 - 0.0088 16.0 6.4 0.02 14.9 6.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1043) AAA_13 PF13166.6 EJP67652.1 - 0.0088 14.7 1.2 0.011 14.4 1.2 1.1 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.8 EJP67652.1 - 0.0088 13.6 12.0 0.011 13.3 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HSD3 PF15244.6 EJP67652.1 - 0.012 15.1 2.4 0.02 14.4 2.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Prominin PF05478.11 EJP67652.1 - 0.023 12.7 2.1 0.03 12.3 2.1 1.1 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 EJP67652.1 - 0.052 13.6 5.2 0.076 13.1 5.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 EJP67652.1 - 0.063 11.8 3.3 0.089 11.3 3.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family BshC PF10079.9 EJP67652.1 - 0.065 12.0 3.3 0.09 11.5 3.3 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Baculo_PEP_C PF04513.12 EJP67652.1 - 0.094 12.8 6.4 1.5 8.8 0.3 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 EJP67652.1 - 0.11 12.0 10.6 0.17 11.3 10.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 SMBP PF16785.5 EJP67652.1 - 0.15 12.3 1.6 0.54 10.5 1.6 1.9 1 1 0 1 1 1 0 Small metal-binding protein Spc7 PF08317.11 EJP67652.1 - 0.26 10.1 9.4 0.4 9.5 9.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LMBR1 PF04791.16 EJP67652.1 - 0.32 9.9 0.3 0.4 9.5 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Hormone_1 PF00103.20 EJP67652.1 - 0.37 10.5 1.5 1.2 8.8 1.6 1.7 1 1 0 1 1 1 0 Somatotropin hormone family Atg14 PF10186.9 EJP67652.1 - 0.39 9.8 3.8 0.57 9.2 3.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1216 PF06746.11 EJP67652.1 - 0.41 10.7 3.2 0.66 10.0 1.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1216) TMPIT PF07851.13 EJP67652.1 - 0.71 9.1 6.4 1 8.5 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Csm1_N PF18504.1 EJP67652.1 - 0.83 10.0 10.3 1 9.8 6.5 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF1664 PF07889.12 EJP67652.1 - 1.2 9.2 5.7 3.1 7.8 4.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EJP67652.1 - 1.3 8.3 9.7 2 7.7 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Plasmid_RAQPRD PF09686.10 EJP67652.1 - 1.6 9.0 5.3 3.2 8.0 4.4 2.0 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Nup88 PF10168.9 EJP67652.1 - 1.7 6.3 10.1 2.4 5.9 10.1 1.1 1 0 0 1 1 1 0 Nuclear pore component ABC_tran_CTD PF16326.5 EJP67652.1 - 3 8.2 16.5 1.2 9.4 6.2 3.4 2 1 2 4 4 3 0 ABC transporter C-terminal domain 5_nucleotid PF05761.14 EJP67652.1 - 3.4 6.5 4.9 4.7 6.0 4.9 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF572 PF04502.13 EJP67652.1 - 6 6.4 10.4 7.8 6.0 10.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FliD_N PF02465.18 EJP67652.1 - 6.2 7.6 11.8 1.8e+03 -0.3 10.8 3.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CdvA PF18822.1 EJP67652.1 - 6.3 6.6 11.9 5.8 6.8 4.6 2.4 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF2524 PF10732.9 EJP67652.1 - 7 7.0 8.5 0.97 9.8 3.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) OmpH PF03938.14 EJP67652.1 - 7.5 6.9 13.5 17 5.8 13.5 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Ndc80_HEC PF03801.13 EJP67653.1 - 5.1e-59 198.3 0.6 1e-58 197.3 0.6 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DHR10 PF18595.1 EJP67653.1 - 0.00076 19.5 12.6 0.00076 19.5 12.6 3.8 4 1 1 5 5 5 1 Designed helical repeat protein 10 domain Spc7 PF08317.11 EJP67653.1 - 0.0046 15.9 33.2 0.081 11.8 13.2 2.7 2 0 0 2 2 2 2 Spc7 kinetochore protein TetR_C_1 PF02909.17 EJP67653.1 - 0.013 15.4 0.3 0.031 14.1 0.3 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Uso1_p115_C PF04871.13 EJP67653.1 - 0.013 15.9 13.2 0.013 15.9 13.2 3.7 3 1 1 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ntox28 PF15605.6 EJP67653.1 - 0.022 15.0 12.2 0.093 13.0 0.6 3.8 2 2 1 4 4 4 0 Bacterial toxin 28 Fungal_TACC PF12709.7 EJP67653.1 - 0.044 14.2 17.5 0.063 13.7 2.1 5.0 3 2 3 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2935 PF11155.8 EJP67653.1 - 0.047 14.0 0.4 2.1 8.7 0.0 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF4140 PF13600.6 EJP67653.1 - 0.066 13.7 0.3 0.066 13.7 0.3 4.7 4 1 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) FliJ PF02050.16 EJP67653.1 - 0.11 12.7 22.4 0.056 13.7 4.6 3.5 2 2 0 2 2 2 0 Flagellar FliJ protein DUF948 PF06103.11 EJP67653.1 - 0.15 12.3 12.1 2 8.7 0.8 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 EJP67653.1 - 0.52 9.9 39.3 0.077 12.6 15.0 3.0 2 2 0 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.12 EJP67653.1 - 0.92 10.0 9.2 14 6.3 0.1 4.2 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 EJP67653.1 - 1 8.7 40.9 0.69 9.3 12.9 3.2 2 2 1 3 3 3 0 Golgin subfamily A member 5 APG6_N PF17675.1 EJP67653.1 - 1.8 9.1 43.2 15 6.1 0.1 4.4 3 1 0 3 3 3 0 Apg6 coiled-coil region DUF2353 PF09789.9 EJP67653.1 - 2.9 7.2 34.0 0.88 8.9 3.9 3.1 2 1 2 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) BLOC1_2 PF10046.9 EJP67653.1 - 4.5 7.6 29.1 0.54 10.6 3.3 5.5 4 2 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 EJP67653.1 - 5.4 6.0 20.7 2.8 6.9 7.2 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EJP67653.1 - 7.3 6.6 21.0 0.33 11.0 1.3 4.4 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Ribosomal_L7Ae PF01248.26 EJP67654.1 - 3.6e-21 74.7 0.1 4.6e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EJP67654.1 - 0.00089 19.3 0.0 0.00089 19.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EJP67654.1 - 0.098 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Lactamase_B_2 PF12706.7 EJP67655.1 - 1.3e-26 93.3 0.0 6.3e-25 87.9 0.0 2.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EJP67655.1 - 6.6e-09 35.9 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EJP67655.1 - 0.012 15.6 5.0 0.045 13.8 2.7 2.7 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Antifungal_pept PF11410.8 EJP67656.1 - 2.5e-29 100.9 32.3 4.1e-15 55.4 10.7 2.2 2 0 0 2 2 2 2 Antifungal peptide Conotoxin PF02950.17 EJP67656.1 - 0.067 14.2 17.5 0.61 11.1 5.1 2.2 1 1 1 2 2 2 0 Conotoxin Tryp_inh PF17983.1 EJP67656.1 - 0.74 10.0 20.8 1.8 8.7 5.8 2.3 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 Orthopox_F7 PF05813.12 EJP67656.1 - 3 8.0 9.9 5.1 7.3 1.1 2.4 2 0 0 2 2 2 0 Orthopoxvirus F7 protein Toxin_29 PF08116.11 EJP67656.1 - 4.5 7.4 25.0 1.8 8.7 6.5 2.7 3 0 0 3 3 3 0 PhTx neurotoxin family Toxin_27 PF08099.11 EJP67656.1 - 7.1 6.8 23.1 2 8.6 8.2 2.8 2 1 0 2 2 2 0 Scorpion calcine family Pex24p PF06398.11 EJP67657.1 - 0.041 12.9 6.3 0.055 12.4 6.3 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Flavoprotein PF02441.19 EJP67659.1 - 2.6e-49 167.0 0.0 3.1e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein DUF445 PF04286.12 EJP67662.1 - 1.7 8.4 17.7 0.19 11.5 9.3 3.0 3 2 0 3 3 3 0 Protein of unknown function (DUF445) DUF5070 PF16802.5 EJP67663.1 - 0.055 13.4 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5070) PTR2 PF00854.21 EJP67664.1 - 1.7e-88 297.2 3.9 3.8e-88 296.0 3.9 1.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 EJP67664.1 - 1.5e-07 30.6 20.1 9.9e-07 28.0 20.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_61 PF03443.14 EJP67667.1 - 0.049 13.6 0.0 0.69 9.8 0.0 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 Zn_clus PF00172.18 EJP67669.1 - 7.3e-09 35.6 5.6 1.5e-08 34.6 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP67669.1 - 1.7e-07 30.4 0.0 2.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EJP67670.1 - 1e-47 162.8 0.0 1.2e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67670.1 - 1.8e-08 34.3 10.7 2.9e-08 33.7 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 EJP67671.1 - 4.1e-07 30.2 2.3 4.3e-05 23.6 1.7 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Fungal_trans PF04082.18 EJP67672.1 - 1e-23 83.7 0.0 1.9e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67672.1 - 1.3e-09 38.0 11.2 2e-09 37.4 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BPL_LplA_LipB PF03099.19 EJP67673.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family XPA_C PF05181.12 EJP67674.1 - 1.8e-26 91.9 1.7 4e-26 90.7 1.7 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EJP67674.1 - 0.027 14.5 6.4 0.027 14.5 6.4 1.8 2 0 0 2 2 2 0 XPA protein N-terminal FRG1 PF06229.12 EJP67674.1 - 0.034 13.8 0.5 0.078 12.7 0.5 1.6 1 0 0 1 1 1 0 FRG1-like domain zf-C3HC4_3 PF13920.6 EJP67674.1 - 0.058 13.3 6.6 0.076 12.9 4.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GFA PF04828.14 EJP67674.1 - 1 9.7 5.8 6.5 7.2 0.0 3.3 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Pho88 PF10032.9 EJP67675.1 - 5.9e-84 279.9 0.8 6.6e-84 279.7 0.8 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4345 PF14248.6 EJP67675.1 - 0.028 14.3 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) NTP_transf_9 PF04248.12 EJP67676.1 - 2.7e-32 110.5 0.1 3.5e-32 110.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) MFS_1 PF07690.16 EJP67677.1 - 6.8e-16 58.1 21.3 9.9e-16 57.6 21.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 EJP67678.1 - 9.6e-45 153.5 0.0 1.2e-44 153.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.9 EJP67678.1 - 0.052 13.5 0.0 0.11 12.4 0.1 1.5 2 0 0 2 2 2 0 Axonemal dynein light chain Sulfotransfer_4 PF17784.1 EJP67679.1 - 2.1e-53 181.4 0.2 2.5e-53 181.1 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EJP67679.1 - 0.028 14.8 0.1 0.05 14.0 0.1 1.5 1 1 0 1 1 1 0 Sulfotransferase family CRAL_TRIO PF00650.20 EJP67680.1 - 1.6e-41 141.7 0.0 2.5e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJP67680.1 - 5.2e-08 32.9 0.1 1.3e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EJP67680.1 - 0.0035 17.5 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FA_desaturase PF00487.24 EJP67681.1 - 2.1e-31 109.7 20.2 3e-31 109.2 20.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EJP67681.1 - 5.5e-07 29.6 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.29 EJP67682.1 - 3.7e-41 140.8 0.0 2.7e-40 138.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP67682.1 - 2.8e-21 75.9 0.0 9.7e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP67682.1 - 3.1e-06 27.3 0.0 5.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EJP67682.1 - 0.02 14.6 0.2 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 EJP67682.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Helicase Metallophos PF00149.28 EJP67683.1 - 2.4e-16 60.9 0.0 4.6e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EJP67683.1 - 5.8e-13 49.5 0.0 1.5e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EJP67683.1 - 3.2e-12 46.9 1.5 6.2e-12 45.9 1.5 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 EJP67683.1 - 0.00055 20.2 0.9 0.0012 19.2 0.9 1.5 1 0 0 1 1 1 1 Fibronectin type III domain PhoD_N PF16655.5 EJP67683.1 - 0.03 14.9 0.0 0.061 13.9 0.0 1.5 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Zn_clus PF00172.18 EJP67684.1 - 2.1e-08 34.2 5.8 3.2e-08 33.6 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP67684.1 - 0.026 13.4 0.0 0.05 12.4 0.0 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain APH PF01636.23 EJP67685.1 - 4e-05 23.7 0.2 7.2e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FAD_binding_3 PF01494.19 EJP67686.1 - 2.2e-15 56.8 0.1 9.8e-15 54.6 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EJP67686.1 - 0.00012 21.5 0.0 0.034 13.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP67686.1 - 0.00039 20.9 0.0 0.0041 17.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP67686.1 - 0.0014 18.8 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP67686.1 - 0.0023 17.6 0.0 0.0098 15.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 EJP67686.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EJP67686.1 - 0.22 10.8 0.0 5.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 EJP67687.1 - 1.7e-14 53.5 0.5 2.4e-14 53.0 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67687.1 - 9.8e-08 32.0 11.8 2.1e-07 30.9 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP_TPR_like PF17004.5 EJP67688.1 - 0.042 13.9 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative TPR-like repeat zf-C2H2_2 PF12756.7 EJP67689.1 - 3.8e-20 72.1 8.9 6.5e-20 71.4 8.9 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.19 EJP67689.1 - 2.8 8.3 8.3 32 4.9 8.3 2.4 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein LPMO_10 PF03067.15 EJP67690.1 - 0.018 15.7 0.1 0.032 14.9 0.1 1.4 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 EJP67690.1 - 0.025 14.5 0.0 0.053 13.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.19 EJP67691.1 - 2.6e-21 76.3 0.0 6.7e-21 74.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJP67691.1 - 1.1e-11 45.0 0.2 1.5e-06 28.1 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EJP67691.1 - 9.2e-07 28.1 0.4 0.034 13.0 0.1 2.6 2 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EJP67691.1 - 2.4e-06 27.0 0.1 0.0034 16.7 0.1 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP67691.1 - 2.4e-05 24.4 0.0 0.0093 16.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EJP67691.1 - 2.9e-05 24.2 0.1 6e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP67691.1 - 0.0019 17.3 0.2 0.0031 16.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EJP67691.1 - 0.0033 16.2 0.0 0.043 12.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 EJP67691.1 - 0.0047 16.0 0.0 0.95 8.5 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Lycopene_cycl PF05834.12 EJP67691.1 - 0.025 13.7 0.5 0.17 10.9 0.4 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EJP67691.1 - 0.038 13.3 0.1 8.7 5.5 0.1 2.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 EJP67691.1 - 0.061 12.6 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EJP67691.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 EJP67692.1 - 1.1e-28 99.7 0.0 4e-08 33.7 0.0 4.4 4 0 0 4 4 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP67692.1 - 3.7e-18 65.6 0.3 4.2e-06 27.2 0.0 5.8 2 2 4 6 6 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EJP67692.1 - 1.1e-17 63.6 0.0 0.0002 21.7 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EJP67692.1 - 4.9e-17 60.3 0.1 0.0014 18.9 0.0 8.0 9 0 0 9 9 7 4 Ankyrin repeat Ank_5 PF13857.6 EJP67692.1 - 3.1e-15 56.0 0.0 0.00013 22.2 0.0 5.8 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Goodbye PF17109.5 EJP67692.1 - 9e-05 22.9 0.0 0.00032 21.1 0.0 2.0 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EJP67692.1 - 0.00014 21.8 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EJP67692.1 - 0.00021 21.6 0.0 0.00073 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EJP67692.1 - 0.0014 17.8 0.0 0.0044 16.2 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EJP67692.1 - 0.0021 18.5 0.0 0.016 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain PRTase_3 PF15610.6 EJP67692.1 - 0.016 14.5 0.1 2 7.6 0.0 2.4 2 0 0 2 2 2 0 PRTase ComF-like ATPase_2 PF01637.18 EJP67692.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EJP67692.1 - 0.041 13.1 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 EJP67692.1 - 0.052 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EJP67692.1 - 0.068 13.7 0.1 1.7 9.2 0.0 2.8 1 1 1 2 2 2 0 AAA domain APS_kinase PF01583.20 EJP67692.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Acetyltransf_10 PF13673.7 EJP67693.1 - 1.2e-10 41.4 0.0 1.8e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP67693.1 - 3.6e-08 33.6 0.0 4.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP67693.1 - 3.6e-05 24.1 0.0 5.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJP67693.1 - 0.0016 18.6 0.0 0.002 18.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP67693.1 - 0.016 15.3 0.0 0.048 13.7 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EJP67693.1 - 0.02 15.0 0.2 0.029 14.5 0.2 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 EJP67693.1 - 0.033 13.9 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DUF4724 PF15852.5 EJP67694.1 - 0.057 13.9 0.1 0.071 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) NAD_binding_10 PF13460.6 EJP67695.1 - 1.7e-08 34.6 0.0 2.6e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DUF1079 PF06435.11 EJP67695.1 - 0.066 13.4 1.5 0.066 13.4 1.5 1.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) NAD_binding_10 PF13460.6 EJP67696.1 - 1.8e-11 44.3 0.0 3.3e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EJP67696.1 - 2.7e-08 33.6 0.0 4.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EJP67696.1 - 9.4e-06 25.3 0.1 0.0066 15.9 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP67696.1 - 0.0051 16.3 0.1 0.43 9.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EJP67696.1 - 0.0053 17.3 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EJP67696.1 - 0.14 11.2 0.1 0.99 8.4 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain p450 PF00067.22 EJP67697.1 - 1.3e-51 175.8 0.0 1.8e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF829 PF05705.14 EJP67698.1 - 2.2e-40 139.1 0.0 2.6e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Beta-lactamase PF00144.24 EJP67699.1 - 1.8e-48 165.5 2.2 3.5e-48 164.6 2.2 1.3 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EJP67699.1 - 0.00095 18.8 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase enzyme family RNase_H PF00075.24 EJP67700.1 - 2.7e-20 73.0 0.0 4e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EJP67700.1 - 0.0014 18.5 0.0 0.49 10.2 0.0 2.4 2 1 0 2 2 2 2 Reverse transcriptase-like Snf7 PF03357.21 EJP67701.1 - 4.7e-07 29.6 23.8 4.7e-07 29.6 23.8 1.8 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 EJP67701.1 - 0.0081 16.1 7.2 0.013 15.4 7.2 1.4 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SCVP PF17619.2 EJP67701.1 - 0.71 10.8 5.0 0.4 11.6 1.0 2.4 2 1 0 2 2 2 0 Secreted clade V proteins ASL_C PF08328.11 EJP67701.1 - 0.83 9.8 8.0 0.28 11.3 2.9 2.4 1 1 2 3 3 3 0 Adenylosuccinate lyase C-terminal PFEMP PF03011.15 EJP67701.1 - 1.7 9.3 13.9 1.1 9.9 2.1 2.2 1 1 1 2 2 2 0 PFEMP DBL domain CEL_III_C PF18054.1 EJP67701.1 - 2.7 8.0 7.3 2.7 8.1 6.3 1.4 1 1 0 1 1 1 0 CEL-III C-terminal DSHCT PF08148.12 EJP67702.1 - 2.9e-51 173.4 0.5 6.6e-51 172.2 0.5 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EJP67702.1 - 4.8e-41 139.7 0.1 2.8e-40 137.3 0.1 2.1 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EJP67702.1 - 1.7e-32 113.5 0.2 2.9e-32 112.7 0.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EJP67702.1 - 9.4e-19 67.8 0.2 7.9e-18 64.8 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP67702.1 - 4.8e-07 30.1 0.0 1.6e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP67702.1 - 4.1e-06 26.9 0.0 7.2e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cut8 PF08559.10 EJP67702.1 - 0.0074 15.9 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Transket_pyr PF02779.24 EJP67703.1 - 6.6e-45 153.0 0.0 9.3e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EJP67703.1 - 6.5e-36 122.9 0.0 2e-35 121.4 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain FtsA PF14450.6 EJP67703.1 - 0.11 12.9 0.0 0.45 11.0 0.0 1.9 2 1 0 2 2 2 0 Cell division protein FtsA Sterol_MT_C PF08498.10 EJP67704.1 - 4.5e-31 107.0 0.1 8.4e-31 106.1 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EJP67704.1 - 3.8e-21 75.6 0.0 6.8e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP67704.1 - 6.5e-20 71.6 0.0 1.5e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP67704.1 - 7.5e-18 64.8 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP67704.1 - 6.8e-12 45.5 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJP67704.1 - 9.1e-12 44.8 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EJP67704.1 - 8.7e-11 42.4 0.0 2.6e-10 40.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP67704.1 - 2e-10 40.4 0.0 3.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 EJP67704.1 - 0.00025 19.8 0.0 0.00034 19.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 EJP67704.1 - 0.00044 20.1 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EJP67704.1 - 0.00084 18.9 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EJP67704.1 - 0.0021 17.5 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EJP67704.1 - 0.0024 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EJP67704.1 - 0.0048 16.5 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EJP67704.1 - 0.0066 15.8 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 EJP67704.1 - 0.0098 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EJP67704.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 EJP67704.1 - 0.035 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 EJP67704.1 - 0.07 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.6 EJP67704.1 - 0.1 13.6 0.1 0.36 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Hormone_3 PF00159.18 EJP67704.1 - 0.16 12.0 0.8 0.42 10.7 0.8 1.7 1 0 0 1 1 1 0 Pancreatic hormone peptide RRM_1 PF00076.22 EJP67705.1 - 1e-09 38.1 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EJP67705.1 - 0.0027 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EJP67705.1 - 0.0036 17.1 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EJP67705.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Complex1_LYR_2 PF13233.6 EJP67706.1 - 0.0028 18.4 0.1 0.0045 17.7 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EJP67706.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) RAC_head PF16717.5 EJP67707.1 - 2.7e-31 108.4 4.5 2.7e-31 108.4 4.5 3.8 4 1 0 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 EJP67707.1 - 3.6e-19 68.6 4.0 6.2e-19 67.9 2.4 2.4 2 0 0 2 2 2 1 DnaJ domain TCTP PF00838.17 EJP67708.1 - 9.1e-67 224.5 0.7 1e-66 224.4 0.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein BMC PF00936.19 EJP67708.1 - 0.025 14.6 0.2 0.04 13.9 0.2 1.4 1 0 0 1 1 1 0 BMC domain AIM3 PF17096.5 EJP67709.1 - 0.0065 17.4 0.1 0.0065 17.4 0.1 4.8 4 1 0 4 4 4 2 Altered inheritance of mitochondria protein 3 RPEL PF02755.15 EJP67710.1 - 0.07 12.9 0.4 0.17 11.6 0.4 1.7 1 0 0 1 1 1 0 RPEL repeat Tnp_22_trimer PF17489.2 EJP67710.1 - 0.34 10.9 6.0 7.8 6.6 0.3 2.8 2 0 0 2 2 2 0 L1 transposable element trimerization domain Pkinase PF00069.25 EJP67711.1 - 3.4e-43 147.9 0.0 4.8e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67711.1 - 7.3e-27 94.3 0.0 9.9e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP67711.1 - 5.2e-05 22.7 0.0 0.00015 21.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like FHA PF00498.26 EJP67711.1 - 7.7e-05 23.0 0.0 0.00054 20.2 0.0 2.2 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EJP67711.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain HsbA PF12296.8 EJP67712.1 - 3e-26 92.2 11.8 4.1e-26 91.8 11.8 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A F_actin_bind PF08919.10 EJP67712.1 - 0.0057 16.7 0.1 0.012 15.7 0.0 1.5 2 0 0 2 2 2 1 F-actin binding DUF1542 PF07564.11 EJP67712.1 - 3.7 7.7 7.6 0.89 9.7 0.5 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) HsbA PF12296.8 EJP67713.1 - 5.4e-22 78.5 6.0 5.4e-22 78.5 6.0 2.0 2 0 0 2 2 2 1 Hydrophobic surface binding protein A KAR9 PF08580.10 EJP67713.1 - 7.7 4.9 7.9 16 3.9 0.0 2.1 2 0 0 2 2 2 0 Yeast cortical protein KAR9 DUF3712 PF12505.8 EJP67714.1 - 1.1e-10 41.9 2.4 7.1e-10 39.2 0.4 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3712) FA_hydroxylase PF04116.13 EJP67715.1 - 3.1e-22 79.4 10.0 3.1e-22 79.4 10.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PHO4 PF01384.20 EJP67715.1 - 0.095 11.7 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family CLTH PF10607.9 EJP67716.1 - 2.7e-31 108.5 0.0 4.4e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EJP67716.1 - 3.2e-09 36.4 0.0 9.1e-09 35.0 0.0 1.9 1 0 0 1 1 1 1 LisH ETC_C1_NDUFA4 PF04800.12 EJP67717.1 - 1.3e-36 124.7 1.9 2e-36 124.1 1.9 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 EJP67718.1 - 2.6e-41 140.0 0.2 2.9e-41 139.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi MCM PF00493.23 EJP67720.1 - 1.6e-102 341.4 0.4 2.5e-102 340.8 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJP67720.1 - 4.8e-39 133.1 0.3 8.8e-39 132.2 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EJP67720.1 - 3.1e-29 101.4 0.0 6.8e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain RNase_H2_suC PF08615.11 EJP67720.1 - 4.6e-25 88.4 0.0 1.2e-24 87.1 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MCM_lid PF17855.1 EJP67720.1 - 2.7e-24 85.4 1.1 4.7e-24 84.6 0.2 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EJP67720.1 - 4.5e-21 75.4 0.1 1.4e-20 73.8 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EJP67720.1 - 8e-07 28.6 0.0 2.3e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EJP67720.1 - 0.0027 17.6 0.3 0.007 16.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJP67720.1 - 0.0074 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EJP67720.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CMAS PF02353.20 EJP67721.1 - 1.2e-71 241.3 0.0 2.7e-71 240.1 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EJP67721.1 - 9.2e-11 42.3 0.0 2.2e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67721.1 - 9.9e-11 42.2 0.0 2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP67721.1 - 5.3e-10 39.4 0.0 9.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP67721.1 - 4.6e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP67721.1 - 1.5e-05 25.7 0.0 3.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EJP67721.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 EJP67721.1 - 0.095 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.20 EJP67721.1 - 0.098 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RNase_T PF00929.24 EJP67722.1 - 1.6e-14 54.8 0.0 8.6e-14 52.4 0.0 2.0 1 1 0 1 1 1 1 Exonuclease MOZ_SAS PF01853.18 EJP67723.1 - 6.8e-78 260.4 0.0 9.3e-78 260.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EJP67723.1 - 6.8e-22 76.8 0.6 1.3e-21 76.0 0.6 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EJP67723.1 - 8.1e-17 60.9 0.0 1.6e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EJP67723.1 - 0.00041 20.7 0.0 0.00073 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP67723.1 - 0.018 15.2 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glyco_hydro_125 PF06824.11 EJP67724.1 - 6.5e-178 591.9 0.0 7.6e-178 591.6 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Beta-lactamase PF00144.24 EJP67725.1 - 1.2e-64 218.7 0.5 1.4e-64 218.4 0.5 1.0 1 0 0 1 1 1 1 Beta-lactamase Aminotran_1_2 PF00155.21 EJP67726.1 - 3.8e-26 92.1 0.0 4.8e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CDC27 PF09507.10 EJP67727.1 - 3.6e-78 263.9 25.7 5.5e-78 263.3 25.7 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 CDC45 PF02724.14 EJP67727.1 - 0.12 10.7 17.0 0.2 9.9 17.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 EJP67727.1 - 0.21 10.4 12.2 0.37 9.6 12.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 EJP67727.1 - 0.99 8.7 7.2 1.5 8.0 7.2 1.3 1 0 0 1 1 1 0 NOA36 protein zf-C3HC4_2 PF13923.6 EJP67728.1 - 8.3e-13 48.0 9.5 8.3e-13 48.0 9.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP67728.1 - 2.5e-08 33.7 10.7 2.5e-08 33.7 10.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP67728.1 - 8.3e-08 32.1 7.0 8.3e-08 32.1 7.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EJP67728.1 - 1.3e-07 31.4 11.3 1.1e-05 25.2 7.4 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EJP67728.1 - 2e-07 30.8 7.2 2e-07 30.8 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP67728.1 - 8.9e-07 28.8 9.1 8.9e-07 28.8 9.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EJP67728.1 - 6e-06 26.5 9.7 6e-06 26.5 9.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 EJP67728.1 - 9.3e-06 25.4 3.0 1.7e-05 24.6 3.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EJP67728.1 - 3.4e-05 24.0 3.9 3.4e-05 24.0 3.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EJP67728.1 - 3.7e-05 23.8 9.8 3.7e-05 23.8 9.8 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EJP67728.1 - 0.00084 19.4 4.1 0.0019 18.3 4.1 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 SAP PF02037.27 EJP67728.1 - 0.00097 18.8 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain U-box PF04564.15 EJP67728.1 - 0.0056 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_4 PF14570.6 EJP67728.1 - 0.011 15.5 3.6 0.011 15.5 3.6 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Mob_synth_C PF06463.13 EJP67728.1 - 0.022 14.7 2.4 0.046 13.7 2.4 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Rad50_zn_hook PF04423.14 EJP67728.1 - 0.17 11.8 0.9 18 5.2 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 EJP67728.1 - 0.17 11.9 3.9 0.12 12.4 0.8 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 EJP67728.1 - 3.6 7.3 9.9 0.62 9.8 5.8 1.8 2 0 0 2 2 2 0 P-11 zinc finger Snf7 PF03357.21 EJP67729.1 - 1.5e-22 80.0 14.3 2.1e-22 79.6 14.3 1.2 1 0 0 1 1 1 1 Snf7 SesA PF17107.5 EJP67729.1 - 0.025 14.8 0.9 0.025 14.8 0.9 2.4 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PspA_IM30 PF04012.12 EJP67729.1 - 0.084 12.4 25.2 1.1 8.8 25.2 2.2 1 1 0 1 1 1 0 PspA/IM30 family Vitellogenin_N PF01347.22 EJP67729.1 - 0.34 9.3 3.6 0.44 8.9 3.6 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region YlqD PF11068.8 EJP67729.1 - 2 8.8 7.7 3.7 7.9 2.8 2.4 2 0 0 2 2 2 0 YlqD protein TRAPPC-Trs85 PF12739.7 EJP67730.1 - 2.7e-117 392.2 0.0 5.9e-117 391.1 0.1 1.5 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Bud13 PF09736.9 EJP67731.1 - 1e-51 175.1 9.9 1e-51 175.1 9.9 2.5 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.12 EJP67732.1 - 1.4e-06 27.2 48.7 5.1e-06 25.4 48.7 2.3 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.19 EJP67733.1 - 8.3e-16 58.0 0.0 2.2e-14 53.4 0.0 2.6 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EJP67733.1 - 0.0018 18.5 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain XPG_I_2 PF12813.7 EJP67734.1 - 4.8e-43 147.4 0.0 8.4e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 EJP67734.1 - 0.098 13.0 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 XPG I-region Pribosyltran_N PF13793.6 EJP67735.1 - 1.6e-43 147.3 0.1 6.3e-42 142.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EJP67735.1 - 2.8e-33 115.5 0.1 4.6e-28 98.5 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EJP67735.1 - 6.7e-09 35.5 0.0 4.5e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain adh_short PF00106.25 EJP67736.1 - 1.4e-49 168.3 0.1 2e-49 167.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP67736.1 - 5.5e-32 111.2 0.1 7.3e-32 110.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP67736.1 - 9.8e-11 41.9 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EJP67736.1 - 0.0038 17.5 0.1 0.014 15.7 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 EJP67736.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HET PF06985.11 EJP67737.1 - 5.7e-28 98.1 1.4 5.3e-21 75.5 1.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 EJP67737.1 - 5.6e-14 52.3 0.9 3.5e-07 30.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP67737.1 - 5e-12 46.2 0.0 1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP67737.1 - 7.1e-10 38.9 0.2 1.8e-08 34.5 0.2 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP67737.1 - 3.3e-08 33.2 0.0 1.1e-05 25.4 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EJP67737.1 - 4.2e-08 33.3 0.2 1.5e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat MFS_1 PF07690.16 EJP67738.1 - 1.8e-17 63.3 43.4 1.3e-13 50.6 8.9 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily ThiF PF00899.21 EJP67739.1 - 2.4e-22 79.5 0.0 2.2e-21 76.3 0.0 2.3 2 1 0 2 2 2 1 ThiF family zf-RING_14 PF17978.1 EJP67739.1 - 0.0033 17.8 2.4 0.0072 16.7 2.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EJP67739.1 - 0.004 17.1 13.3 0.0074 16.2 13.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EJP67739.1 - 0.0096 16.2 10.0 0.019 15.3 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EJP67739.1 - 0.013 15.7 9.5 0.026 14.7 9.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Halogen_Hydrol PF10112.9 EJP67739.1 - 0.018 15.1 1.7 2.8 7.9 0.5 2.7 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein ZapB PF06005.12 EJP67739.1 - 0.026 14.9 7.6 0.064 13.7 7.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 EJP67739.1 - 0.082 13.0 4.4 0.19 11.8 4.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 EJP67739.1 - 0.09 13.4 5.5 0.27 11.9 5.5 1.8 1 0 0 1 1 1 0 Initiation control protein YabA zf-RING_UBOX PF13445.6 EJP67739.1 - 0.13 12.3 7.0 0.29 11.2 7.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF948 PF06103.11 EJP67739.1 - 0.18 12.1 2.7 0.39 11.0 1.9 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 EJP67739.1 - 0.41 11.0 12.4 0.98 9.8 12.4 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4482 PF14818.6 EJP67739.1 - 0.66 10.8 7.3 1.3 9.9 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) 60KD_IMP PF02096.20 EJP67739.1 - 0.75 9.7 2.2 11 5.9 1.2 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein zf-C3HC4 PF00097.25 EJP67739.1 - 0.87 9.5 12.6 1.7 8.6 12.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJP67739.1 - 0.89 9.5 7.9 2 8.4 7.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EJP67739.1 - 1.3 9.4 7.1 2.8 8.3 7.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF4407 PF14362.6 EJP67739.1 - 1.5 8.1 8.3 2.7 7.3 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_4 PF14570.6 EJP67739.1 - 2 8.3 9.6 3.4 7.5 9.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EJP67739.1 - 2.2 8.2 9.7 4.7 7.1 9.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Occludin_ELL PF07303.13 EJP67739.1 - 3.2 8.5 9.1 1.6 9.5 6.3 2.0 2 0 0 2 2 1 0 Occludin homology domain Pkinase PF00069.25 EJP67740.1 - 4e-14 52.6 0.0 5.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67740.1 - 4.3e-06 26.2 0.0 6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GDA1_CD39 PF01150.17 EJP67741.1 - 3.9e-108 361.8 0.0 4.9e-108 361.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF775 PF05603.12 EJP67742.1 - 1.5e-61 207.4 0.0 1.7e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Sacchrp_dh_C PF16653.5 EJP67743.1 - 5.3e-85 285.7 0.0 1.2e-84 284.5 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EJP67743.1 - 2.3e-24 86.1 3.5 3.8e-24 85.4 3.5 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EJP67743.1 - 1.2e-05 25.4 0.3 2.5e-05 24.4 0.3 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EJP67743.1 - 3.2e-05 23.9 1.7 6.1e-05 23.0 1.7 1.5 1 0 0 1 1 1 1 NAD(P)H-binding AlaDh_PNT_C PF01262.21 EJP67743.1 - 0.0079 15.5 2.0 0.014 14.7 2.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EJP67743.1 - 0.041 14.3 1.0 0.08 13.4 0.5 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 EJP67743.1 - 0.071 13.9 0.6 0.14 13.0 0.6 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox PF00070.27 EJP67743.1 - 0.12 12.9 0.1 0.47 11.0 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HSCB_C PF07743.13 EJP67743.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF4743 PF15916.5 EJP67744.1 - 1.6e-14 53.9 0.0 2.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EJP67744.1 - 1.1e-10 41.7 0.0 2.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 EJP67745.1 - 3.2e-45 153.7 0.0 3.6e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EJP67745.1 - 0.00018 21.5 0.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 EJP67746.1 - 6.4e-107 357.9 0.0 7.2e-107 357.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 EJP67747.1 - 4e-12 46.0 0.0 8.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Arabino_trans_N PF17689.1 EJP67747.1 - 0.014 15.6 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain zf-C3HC4_3 PF13920.6 EJP67748.1 - 4e-08 33.0 12.3 6.5e-08 32.3 12.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SDA1 PF05285.12 EJP67748.1 - 0.0014 18.2 1.1 0.0021 17.6 1.1 1.2 1 0 0 1 1 1 1 SDA1 Prok-RING_4 PF14447.6 EJP67748.1 - 0.089 12.7 11.9 0.15 11.9 11.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SNARE_assoc PF09335.11 EJP67748.1 - 0.51 10.8 4.1 0.43 11.1 0.7 2.4 2 0 0 2 2 2 0 SNARE associated Golgi protein FAM24 PF15193.6 EJP67748.1 - 0.96 10.3 5.4 3 8.7 5.4 1.8 1 0 0 1 1 1 0 FAM24 family RNase_PH PF01138.21 EJP67749.1 - 2.8e-27 95.8 0.0 6e-27 94.7 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Anp1 PF03452.14 EJP67750.1 - 1.7e-112 375.2 0.6 2.6e-112 374.6 0.0 1.5 2 0 0 2 2 2 1 Anp1 Rad54_N PF08658.10 EJP67750.1 - 0.029 14.5 0.5 0.069 13.3 0.5 1.5 1 0 0 1 1 1 0 Rad54 N terminal Sec7 PF01369.20 EJP67751.1 - 5.5e-68 228.3 0.0 1.1e-67 227.3 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EJP67751.1 - 1e-17 64.5 0.0 2e-16 60.3 0.0 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RRN3 PF05327.11 EJP67751.1 - 0.21 10.1 2.1 0.35 9.4 2.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Syja_N PF02383.18 EJP67752.1 - 9.3e-79 265.0 0.0 2e-78 263.9 0.0 1.6 1 0 0 1 1 1 1 SacI homology domain Tti2 PF10521.9 EJP67753.1 - 7.9e-85 284.8 0.0 1.4e-84 283.9 0.0 1.4 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 EJP67754.1 - 1.5e-26 93.3 0.1 5.2e-26 91.5 0.1 2.0 2 1 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EJP67754.1 - 1.6e-09 37.3 0.0 3.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EJP67754.1 - 0.0086 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative TPR_14 PF13428.6 EJP67756.1 - 5.2e-11 42.4 24.2 2.2 9.3 0.1 11.6 11 2 2 13 13 12 3 Tetratricopeptide repeat Suf PF05843.14 EJP67756.1 - 2.6e-09 37.5 13.5 0.077 13.0 0.2 6.6 5 2 0 6 6 6 4 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 EJP67756.1 - 1.6e-08 34.6 9.2 0.47 10.4 0.1 7.1 7 0 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 EJP67756.1 - 3.4e-07 29.8 2.3 2.4e-05 23.7 0.3 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJP67756.1 - 4e-07 29.7 1.1 1.5 9.3 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP67756.1 - 2.5e-05 24.5 2.2 1.2 9.5 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 EJP67756.1 - 0.0017 18.1 0.1 0.011 15.5 0.2 2.4 2 1 0 2 2 2 1 26S proteasome subunit RPN7 NRDE-2 PF08424.10 EJP67756.1 - 0.0081 15.3 0.2 0.0081 15.3 0.2 5.8 3 2 3 6 6 6 1 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 EJP67756.1 - 0.033 14.3 15.4 9.8 6.6 0.0 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat HAT PF02184.16 EJP67756.1 - 0.18 11.8 11.8 2.2 8.3 0.0 6.7 7 0 0 7 7 6 0 HAT (Half-A-TPR) repeat Egg_lysin PF01303.17 EJP67756.1 - 0.32 11.2 2.4 1.1 9.5 0.8 2.7 1 1 0 2 2 2 0 Egg lysin (Sperm-lysin) TPR_10 PF13374.6 EJP67756.1 - 8.5 6.4 9.2 66 3.6 0.1 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat ATP-synt_D PF01813.17 EJP67757.1 - 1.3e-69 234.0 1.6 1.9e-69 233.4 1.6 1.2 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 EJP67757.1 - 0.072 12.6 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) CobA_CobO_BtuR PF02572.15 EJP67757.1 - 0.35 11.1 3.7 0.96 9.7 0.1 2.4 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ISG65-75 PF11727.8 EJP67757.1 - 1.3 8.2 7.8 0.66 9.2 3.4 2.0 2 0 0 2 2 2 0 Invariant surface glycoprotein RRM_1 PF00076.22 EJP67758.1 - 5.4e-21 74.2 1.4 3.9e-10 39.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJP67758.1 - 0.015 14.9 0.0 1.5 8.5 0.0 2.3 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EJP67758.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) HMMR_N PF15905.5 EJP67760.1 - 0.00084 18.9 28.8 0.00084 18.9 28.8 8.5 3 2 5 10 10 10 4 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 EJP67760.1 - 0.0025 17.6 14.4 2.2 8.2 0.4 7.3 6 0 0 6 6 6 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Rsa3 PF14615.6 EJP67760.1 - 0.62 9.7 2.4 16 5.2 0.2 3.8 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Filament PF00038.21 EJP67760.1 - 7 6.1 166.9 0.097 12.2 31.0 8.4 1 1 5 6 6 6 0 Intermediate filament protein MFS_1 PF07690.16 EJP67761.1 - 1.8e-22 79.8 19.7 1.8e-22 79.8 19.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2427 PF10348.9 EJP67761.1 - 0.011 15.5 0.1 0.039 13.8 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DAO PF01266.24 EJP67762.1 - 1.2e-30 107.3 0.0 1.5e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP67762.1 - 8.9e-07 29.0 0.1 2.3e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP67762.1 - 4.7e-05 23.9 0.0 0.00016 22.2 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EJP67762.1 - 0.00034 20.8 0.0 0.0097 16.1 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 EJP67762.1 - 0.002 17.4 0.0 0.0048 16.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP67762.1 - 0.0023 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 EJP67762.1 - 0.0034 17.3 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EJP67762.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.24 EJP67762.1 - 0.046 12.8 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EJP67762.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EJP67762.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Adeno_PVIII PF01310.18 EJP67762.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII TrkA_N PF02254.18 EJP67762.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Amino_oxidase PF01593.24 EJP67763.1 - 1.5e-32 113.5 0.4 1.8e-32 113.2 0.4 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP67763.1 - 0.00011 22.3 0.0 0.00027 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EJP67763.1 - 0.032 13.5 0.3 0.064 12.5 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP67763.1 - 0.057 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amidase PF01425.21 EJP67764.1 - 6.5e-30 104.5 1.1 1.1e-29 103.7 0.6 1.6 2 0 0 2 2 2 1 Amidase MafB PF06255.13 EJP67764.1 - 0.024 14.1 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Neisseria toxin MafB PTPA PF03095.15 EJP67766.1 - 1.1e-118 396.0 0.0 1.3e-118 395.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein CarboxypepD_reg PF13620.6 EJP67768.1 - 0.083 13.2 0.2 0.22 11.8 0.2 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Abhydrolase_3 PF07859.13 EJP67769.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ion_trans_2 PF07885.16 EJP67770.1 - 2.6e-28 97.8 30.1 3.5e-18 65.3 3.3 3.2 3 1 0 3 3 3 2 Ion channel SieB PF14163.6 EJP67770.1 - 0.014 14.8 0.0 0.051 13.1 0.0 1.9 1 0 0 1 1 1 0 Super-infection exclusion protein B Ion_trans PF00520.31 EJP67770.1 - 5.2 6.2 20.1 0.048 12.9 2.6 2.8 2 1 0 2 2 2 0 Ion transport protein zf-RING_4 PF14570.6 EJP67771.1 - 7.2e-20 70.5 12.2 1.3e-19 69.6 12.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EJP67771.1 - 3.7e-08 33.1 0.0 1.1e-06 28.3 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 EJP67771.1 - 4.5e-07 29.6 7.6 4.5e-07 29.6 7.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EJP67771.1 - 8.5e-05 22.0 3.3 8.5e-05 22.0 3.3 3.5 4 1 1 5 5 4 1 Rtf2 RING-finger zf-RING_2 PF13639.6 EJP67771.1 - 0.00039 20.7 9.8 0.001 19.4 9.8 1.7 1 0 0 1 1 1 1 Ring finger domain SET_assoc PF11767.8 EJP67771.1 - 0.0036 16.9 0.0 0.0084 15.7 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 EJP67771.1 - 0.0045 16.8 8.7 0.13 12.1 9.5 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 EJP67771.1 - 0.096 12.6 5.1 0.18 11.8 5.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 EJP67771.1 - 0.11 12.7 5.0 0.29 11.3 5.0 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 EJP67771.1 - 0.11 12.4 10.3 0.26 11.2 10.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.6 EJP67771.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-RING_5 PF14634.6 EJP67771.1 - 0.17 11.8 9.8 0.43 10.6 9.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Complex1_30kDa PF00329.19 EJP67772.1 - 1.9e-44 151.2 0.0 2.5e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Zds_C PF08632.10 EJP67773.1 - 1.3e-29 101.7 0.8 2.4e-29 100.8 0.8 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2433 PF10360.9 EJP67774.1 - 1.6e-49 167.1 0.0 2.7e-49 166.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EJP67774.1 - 0.00054 20.5 0.0 0.0011 19.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP67774.1 - 0.0011 19.2 0.0 0.0052 17.0 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ubie_methyltran PF01209.18 EJP67775.1 - 1.1e-82 276.9 0.0 1.3e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EJP67775.1 - 1.9e-15 57.4 0.0 7.4e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67775.1 - 6.1e-14 52.4 0.0 5.7e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP67775.1 - 7e-13 48.6 0.0 9.8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP67775.1 - 1.3e-10 41.8 0.0 5.4e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP67775.1 - 2.8e-08 33.8 0.0 4.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EJP67775.1 - 0.038 13.9 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 EJP67775.1 - 0.16 11.9 0.0 0.89 9.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain E1_dh PF00676.20 EJP67776.1 - 2.2e-88 296.1 0.0 2.6e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EJP67776.1 - 0.003 17.3 0.0 0.045 13.5 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FliT PF05400.13 EJP67776.1 - 0.046 14.5 0.7 0.094 13.5 0.7 1.5 1 0 0 1 1 1 0 Flagellar protein FliT DAO_C PF16901.5 EJP67776.1 - 0.091 12.6 0.4 0.2 11.5 0.4 1.6 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase HECT PF00632.25 EJP67778.1 - 5.6e-72 242.8 0.0 8.4e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EJP67778.1 - 9.8e-05 22.3 7.4 0.95 9.6 0.1 6.0 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EJP67778.1 - 0.00035 20.6 1.5 0.97 9.9 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EJP67778.1 - 0.0023 18.4 0.4 3.5 8.2 0.1 3.3 2 0 0 2 2 2 2 HEAT-like repeat MMS19_N PF14500.6 EJP67778.1 - 0.037 13.6 2.4 0.95 9.0 0.1 3.6 4 1 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 EJP67778.1 - 0.07 12.7 0.2 0.48 9.9 0.0 2.3 2 0 0 2 2 2 0 CLASP N terminal DUF1833 PF08875.11 EJP67778.1 - 0.17 11.5 0.4 2 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1833) PET10 PF17316.2 EJP67778.1 - 0.2 11.1 1.2 9.8 5.6 0.0 2.8 2 1 0 2 2 2 0 Petite colonies protein 10 HEAT_2 PF13646.6 EJP67778.1 - 0.24 11.8 2.3 3.9 7.9 0.1 3.3 3 0 0 3 3 3 0 HEAT repeats Sec3_C PF09763.9 EJP67780.1 - 4.9e-224 745.8 0.0 6.4e-224 745.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EJP67780.1 - 2.5e-29 101.3 0.0 1.1e-28 99.2 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 EJP67780.1 - 0.00015 22.0 1.9 0.0039 17.5 0.0 2.9 3 0 0 3 3 3 1 Sec3 exocyst complex subunit Vps52 PF04129.12 EJP67780.1 - 0.079 11.7 0.3 0.32 9.7 0.1 1.9 2 0 0 2 2 2 0 Vps52 / Sac2 family Peptidase_S58 PF03576.14 EJP67781.1 - 1.7e-107 359.4 0.0 1.9e-107 359.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S58 RasGAP PF00616.19 EJP67783.1 - 2.3e-30 105.9 0.1 6.5e-22 78.3 0.0 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EJP67783.1 - 1.7e-05 25.0 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF5559 PF17714.1 EJP67784.1 - 0.092 12.6 0.7 0.18 11.7 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5559) AA_permease_2 PF13520.6 EJP67785.1 - 2.8e-46 158.2 50.4 3.3e-46 158.0 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP67785.1 - 2e-19 69.6 42.1 2.7e-19 69.1 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease Poxvirus PF06227.12 EJP67785.1 - 0.25 11.1 0.4 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 dsDNA Poxvirus Aa_trans PF01490.18 EJP67786.1 - 5.2e-39 134.1 35.9 5.9e-39 133.9 35.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PepSY_TM PF03929.16 EJP67786.1 - 4 7.0 12.0 0.15 11.7 1.4 2.7 2 1 0 2 2 2 0 PepSY-associated TM region Pro_isomerase PF00160.21 EJP67787.1 - 2e-48 164.7 0.0 3.3e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 EJP67787.1 - 1.1e-07 31.3 2.0 1.8e-06 27.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EJP67787.1 - 2.6e-07 30.2 5.7 7e-06 25.8 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJP67787.1 - 5e-05 23.2 1.9 0.00069 19.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP67787.1 - 0.0017 18.6 2.1 0.0017 18.6 2.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP67787.1 - 0.0036 17.9 5.2 0.0096 16.5 3.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EJP67787.1 - 0.008 16.3 0.2 0.03 14.5 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EJP67787.1 - 0.026 15.2 0.4 0.23 12.2 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP67787.1 - 0.041 14.7 1.7 0.16 12.9 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.16 EJP67788.1 - 9.9e-45 152.6 0.4 2.2e-43 148.2 0.4 2.0 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Mesd PF10185.9 EJP67788.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Not3 PF04065.15 EJP67789.1 - 9.2e-91 303.4 22.8 1.4e-90 302.8 22.8 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EJP67789.1 - 3.5e-44 150.1 8.5 9.1e-44 148.7 8.5 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.11 EJP67789.1 - 0.003 17.6 1.1 0.003 17.6 1.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1192) DUF2373 PF10180.9 EJP67789.1 - 0.0067 16.2 3.8 0.015 15.1 3.8 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 EJP67789.1 - 0.028 14.8 1.4 0.028 14.8 1.4 2.6 3 0 0 3 3 3 0 Syntaxin-like protein Wyosine_form PF08608.12 EJP67789.1 - 0.15 12.4 0.0 0.48 10.8 0.0 1.8 1 0 0 1 1 1 0 Wyosine base formation CorA PF01544.18 EJP67789.1 - 0.22 10.8 3.9 0.12 11.6 1.5 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Cep57_MT_bd PF06657.13 EJP67789.1 - 0.28 11.7 8.8 4.1 7.9 1.4 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Nnf1 PF03980.14 EJP67789.1 - 0.64 10.4 8.5 3.7 8.0 8.0 2.6 1 1 1 2 2 2 0 Nnf1 HR1 PF02185.16 EJP67789.1 - 0.8 9.9 10.8 0.26 11.4 0.3 3.0 3 0 0 3 3 3 0 Hr1 repeat DUF4140 PF13600.6 EJP67789.1 - 3.8 8.0 7.3 7 7.2 0.8 3.1 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF3810 PF12725.7 EJP67789.1 - 4.5 6.5 6.8 10 5.4 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) FOXP-CC PF16159.5 EJP67790.1 - 0.1 13.2 8.2 0.31 11.7 0.2 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain SnAC PF14619.6 EJP67791.1 - 0.69 10.6 6.3 0.091 13.4 1.2 2.2 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex Jnk-SapK_ap_N PF09744.9 EJP67792.1 - 0.00057 20.2 8.2 0.00057 20.2 8.2 5.5 4 1 2 6 6 6 2 JNK_SAPK-associated protein-1 Spc7 PF08317.11 EJP67792.1 - 0.0014 17.5 1.2 0.0014 17.5 1.2 4.9 4 1 1 5 5 5 1 Spc7 kinetochore protein THOC7 PF05615.13 EJP67792.1 - 0.011 16.1 7.1 0.011 16.1 7.1 5.6 4 1 0 6 6 3 0 Tho complex subunit 7 ADIP PF11559.8 EJP67792.1 - 0.018 15.1 7.8 0.018 15.1 7.8 6.0 5 1 2 7 7 7 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 EJP67792.1 - 0.28 11.7 12.9 2.4 8.7 0.0 5.0 5 1 0 5 5 4 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.11 EJP67792.1 - 0.34 10.7 14.6 3 7.6 1.1 3.9 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.11 EJP67792.1 - 0.37 11.2 33.4 1.4 9.4 0.1 7.4 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 EJP67792.1 - 0.4 11.1 0.0 0.19 12.1 11.7 5.8 4 1 3 7 7 6 0 Bacterial type III secretion protein (HrpB7) TSC22 PF01166.18 EJP67792.1 - 1.9 8.8 0.0 1.9 8.9 0.2 6.2 7 1 1 8 8 7 0 TSC-22/dip/bun family KASH_CCD PF14662.6 EJP67792.1 - 4 7.2 51.4 0.027 14.3 9.7 5.2 4 2 1 5 5 5 0 Coiled-coil region of CCDC155 or KASH MbeD_MobD PF04899.12 EJP67792.1 - 4.6 7.4 18.5 0.2 11.8 2.5 4.7 5 0 0 5 5 5 0 MbeD/MobD like HALZ PF02183.18 EJP67792.1 - 5.2 7.4 30.5 6.7 7.0 0.1 6.9 6 1 1 7 7 7 0 Homeobox associated leucine zipper GIT_CC PF16559.5 EJP67792.1 - 6.6 6.7 17.7 0.45 10.4 0.6 5.2 5 0 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor ABC_tran PF00005.27 EJP67793.1 - 4e-16 59.8 0.0 6.8e-10 39.6 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP67793.1 - 0.0013 18.2 0.0 0.1 12.1 0.0 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJP67793.1 - 0.14 12.4 0.3 8.8 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EJP67794.1 - 8.3e-37 126.8 0.5 1.5e-19 70.9 0.2 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP67794.1 - 1.5e-20 74.0 36.8 4.5e-17 62.6 12.8 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP67794.1 - 5.2e-15 55.5 0.0 7.4e-06 25.6 0.1 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP67794.1 - 0.00043 20.2 0.2 8.7 6.0 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EJP67794.1 - 0.0086 15.2 5.1 0.33 10.0 0.2 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 EJP67794.1 - 0.016 14.9 0.0 0.071 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJP67794.1 - 0.026 14.3 1.5 0.24 11.2 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.29 EJP67794.1 - 0.05 13.4 1.2 0.78 9.5 1.2 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 EJP67794.1 - 0.057 13.7 2.1 0.49 10.7 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ResIII PF04851.15 EJP67794.1 - 0.058 13.4 0.6 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EJP67794.1 - 0.084 13.3 0.1 4 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.23 EJP67794.1 - 0.16 12.1 1.2 15 5.7 0.3 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase ATPase PF06745.13 EJP67794.1 - 0.16 11.3 1.6 19 4.5 0.1 2.9 3 0 0 3 3 3 0 KaiC AAA_7 PF12775.7 EJP67794.1 - 0.2 11.1 1.0 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DnaB_C PF03796.15 EJP67794.1 - 0.44 9.8 3.2 0.23 10.8 0.1 2.0 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EJP67794.1 - 1 9.6 5.0 3.7 7.8 1.8 3.0 2 1 0 2 2 2 0 AAA domain Iso_dh PF00180.20 EJP67795.1 - 1.2e-72 245.0 0.0 1.4e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.6 EJP67796.1 - 2.5e-53 182.2 1.7 1.2e-28 101.4 0.3 2.2 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling TMF_DNA_bd PF12329.8 EJP67796.1 - 0.08 13.0 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ABC_tran PF00005.27 EJP67797.1 - 8.3e-50 168.9 0.0 3.7e-31 108.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP67797.1 - 1.7e-25 90.3 25.0 1.5e-18 67.4 14.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP67797.1 - 1.4e-07 31.2 0.9 0.047 13.1 0.0 4.0 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EJP67797.1 - 9.3e-05 22.4 0.1 0.33 10.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EJP67797.1 - 9.9e-05 22.0 0.2 0.31 10.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EJP67797.1 - 0.00014 22.2 0.2 1.3 9.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJP67797.1 - 0.00047 19.8 1.9 0.27 11.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP67797.1 - 0.00063 20.2 1.4 2.1 8.7 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 EJP67797.1 - 0.002 17.2 0.3 0.98 8.4 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 EJP67797.1 - 0.0045 17.1 7.3 0.033 14.3 0.6 2.8 3 0 0 3 3 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 EJP67797.1 - 0.0051 16.9 1.1 0.05 13.7 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EJP67797.1 - 0.018 15.6 0.3 6.9 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EJP67797.1 - 0.018 15.3 0.1 5.6 7.3 0.1 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EJP67797.1 - 0.024 14.1 0.3 0.69 9.4 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region CbiA PF01656.23 EJP67797.1 - 0.031 14.3 2.6 3.7 7.6 0.2 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TsaE PF02367.17 EJP67797.1 - 0.033 14.2 0.1 8.2 6.4 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EJP67797.1 - 0.06 13.3 4.9 0.38 10.6 0.1 3.2 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 EJP67797.1 - 0.11 12.3 0.6 0.18 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 EJP67797.1 - 0.11 12.2 0.7 2.7 7.7 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein RseC_MucC PF04246.12 EJP67797.1 - 0.11 12.4 1.9 0.15 12.0 0.0 2.2 2 0 0 2 2 1 0 Positive regulator of sigma(E), RseC/MucC MeaB PF03308.16 EJP67797.1 - 0.14 11.1 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EJP67797.1 - 0.18 11.0 1.2 10 5.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 EJP67797.1 - 0.31 10.2 2.7 14 4.7 0.2 2.8 3 0 0 3 3 3 0 NB-ARC domain DUF2075 PF09848.9 EJP67797.1 - 0.38 9.9 1.2 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MFS_1 PF07690.16 EJP67798.1 - 5.9e-16 58.3 55.1 3.5e-09 36.1 27.3 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 EJP67798.1 - 2.5e-06 26.2 19.0 3.6e-06 25.7 19.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4325 PF14213.6 EJP67798.1 - 0.14 11.9 0.1 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 STAS-like domain of unknown function (DUF4325) DUF1269 PF06897.12 EJP67798.1 - 0.96 9.8 3.5 0.61 10.4 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Pyr_redox_2 PF07992.14 EJP67799.1 - 2.3e-22 79.6 0.0 3.5e-20 72.4 0.1 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP67799.1 - 1.3e-14 54.5 1.4 2.3e-11 44.1 0.1 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EJP67799.1 - 0.00052 19.4 0.3 0.0092 15.3 0.0 2.1 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 EJP67799.1 - 0.0086 15.3 0.5 0.045 12.9 0.2 2.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EJP67799.1 - 0.068 12.2 0.1 0.16 11.0 0.1 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein PHD_Oberon PF07227.11 EJP67799.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein FAD_binding_3 PF01494.19 EJP67799.1 - 0.26 10.5 0.0 0.26 10.5 0.0 2.9 4 0 0 4 4 4 0 FAD binding domain Pyr_redox_3 PF13738.6 EJP67799.1 - 1.1 8.5 7.0 1.7 7.8 0.4 2.5 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_21 PF05050.12 EJP67800.1 - 3.1e-15 56.6 0.0 5.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 EJP67800.1 - 9.5e-05 21.8 0.1 0.0011 18.3 0.1 2.2 1 1 0 1 1 1 1 Vibrio cholerae RfbT protein Met_10 PF02475.16 EJP67800.1 - 0.0027 17.5 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EJP67800.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EJP67800.1 - 0.064 12.6 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Pyr_redox_3 PF13738.6 EJP67801.1 - 2.1e-27 96.2 0.0 2e-24 86.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP67801.1 - 1.9e-20 73.3 0.0 1.3e-15 57.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EJP67801.1 - 3.9e-19 68.5 0.0 1.3e-17 63.4 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EJP67801.1 - 2.1e-14 53.4 0.8 1.3e-10 41.0 0.1 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EJP67801.1 - 1.1e-09 38.5 3.0 0.022 14.7 0.0 3.5 2 1 1 3 3 3 3 FAD-NAD(P)-binding Pyr_redox PF00070.27 EJP67801.1 - 3.9e-09 37.0 0.1 0.17 12.5 0.2 4.0 4 0 0 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP67801.1 - 7.1e-09 35.7 5.5 0.00034 20.3 0.0 4.3 4 1 1 5 5 5 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EJP67801.1 - 2.9e-07 30.1 0.1 2.5e-06 27.0 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EJP67801.1 - 6.4e-06 25.7 0.1 0.0083 15.4 0.0 2.7 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 EJP67801.1 - 1.5e-05 24.4 0.0 0.083 12.2 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EJP67801.1 - 1.5e-05 25.0 0.1 0.084 12.9 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EJP67801.1 - 2.5e-05 23.6 6.4 0.043 12.9 1.5 3.4 3 1 0 4 4 4 2 FAD binding domain Thi4 PF01946.17 EJP67801.1 - 0.00018 20.8 1.4 0.0068 15.7 0.1 2.9 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 EJP67801.1 - 0.00044 19.4 1.2 0.21 10.7 0.1 3.2 4 0 0 4 4 4 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EJP67801.1 - 0.0005 19.2 7.6 0.005 15.9 0.2 3.6 5 0 0 5 5 5 1 Lycopene cyclase protein HI0933_like PF03486.14 EJP67801.1 - 0.00074 18.3 0.5 0.72 8.5 0.3 2.9 3 0 0 3 3 3 2 HI0933-like protein F420_oxidored PF03807.17 EJP67801.1 - 0.00085 19.9 0.1 17 6.1 0.1 3.6 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 EJP67801.1 - 0.0027 17.9 0.0 0.0068 16.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EJP67801.1 - 0.004 17.4 0.2 2 8.7 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain FAD_oxidored PF12831.7 EJP67801.1 - 0.008 15.6 2.0 0.15 11.4 2.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.21 EJP67801.1 - 0.014 14.8 0.0 0.83 9.0 0.0 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.6 EJP67801.1 - 0.015 15.8 0.1 0.95 9.9 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding IlvN PF07991.12 EJP67801.1 - 0.04 13.5 0.3 2.5 7.6 0.1 2.7 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 EJP67801.1 - 0.079 12.6 0.0 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA SnoaL_4 PF13577.6 EJP67801.1 - 0.14 12.3 1.5 0.34 11.0 0.3 2.4 2 1 0 2 2 2 0 SnoaL-like domain Methyltransf_2 PF00891.18 EJP67802.1 - 1.3e-21 76.9 0.0 2.2e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EJP67802.1 - 0.0026 18.4 0.0 0.0081 16.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP67802.1 - 0.17 12.6 0.0 0.32 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ABC_membrane PF00664.23 EJP67804.1 - 6.3e-88 295.0 26.9 4e-45 154.6 6.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP67804.1 - 2.5e-61 206.2 0.0 4.1e-31 108.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP67804.1 - 4e-13 49.3 0.0 6.1e-05 22.6 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP67804.1 - 9.6e-08 31.7 0.1 0.0054 16.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP67804.1 - 1.1e-06 29.2 2.9 0.01 16.2 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EJP67804.1 - 1.2e-06 28.9 0.2 0.19 12.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EJP67804.1 - 2.8e-06 27.3 0.0 0.0062 16.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EJP67804.1 - 5.4e-06 26.3 5.8 0.00075 19.3 0.1 3.8 4 0 0 4 4 4 2 AAA domain ABC_ATPase PF09818.9 EJP67804.1 - 3.7e-05 22.7 0.4 0.0079 15.0 0.0 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.6 EJP67804.1 - 7e-05 23.4 0.0 0.86 10.2 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EJP67804.1 - 9e-05 22.7 0.0 0.36 11.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 EJP67804.1 - 0.00022 21.7 0.5 3 8.3 0.2 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EJP67804.1 - 0.00026 20.3 0.0 0.15 11.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 EJP67804.1 - 0.00034 21.2 0.0 0.51 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EJP67804.1 - 0.00036 20.7 1.0 0.26 11.4 0.2 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_21 PF13304.6 EJP67804.1 - 0.00038 20.4 0.7 1.1 9.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 EJP67804.1 - 0.0024 17.9 0.0 3.5 7.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EJP67804.1 - 0.0038 16.8 0.0 0.59 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EJP67804.1 - 0.004 17.2 0.1 0.75 9.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase APS_kinase PF01583.20 EJP67804.1 - 0.0068 16.3 0.2 2.7 7.9 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 EJP67804.1 - 0.0072 15.9 0.3 0.97 9.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 EJP67804.1 - 0.0074 15.5 0.4 1.3 8.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain G-alpha PF00503.20 EJP67804.1 - 0.0086 15.3 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_17 PF13207.6 EJP67804.1 - 0.016 15.7 0.0 11 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EJP67804.1 - 0.018 15.3 0.4 10 6.4 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.6 EJP67804.1 - 0.025 13.6 0.1 5.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PRK PF00485.18 EJP67804.1 - 0.032 14.0 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 EJP67804.1 - 0.072 12.5 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EJP67804.1 - 0.077 13.4 0.1 8.2 6.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 EJP67804.1 - 0.099 12.3 0.6 4.9 6.7 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EJP67804.1 - 0.17 11.6 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EJP67804.1 - 0.19 11.4 0.9 15 5.2 0.1 2.4 2 0 0 2 2 2 0 Cytidylate kinase ASFV_L11L PF05293.11 EJP67804.1 - 0.21 11.9 2.5 0.65 10.4 1.9 2.1 2 0 0 2 2 1 0 African swine fever virus (ASFV) L11L protein UDPGT PF00201.18 EJP67805.1 - 5.2e-06 25.5 0.0 7.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EJP67805.1 - 0.0038 17.2 0.0 0.0078 16.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Sec1 PF00995.23 EJP67806.1 - 2.9e-131 439.5 0.0 3.3e-131 439.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family NLRC4_HD2 PF17776.1 EJP67806.1 - 0.11 13.0 0.3 0.32 11.5 0.3 1.8 1 0 0 1 1 1 0 NLRC4 helical domain HD2 GxGYxYP_C PF14323.6 EJP67806.1 - 0.16 11.8 1.4 2.2 8.1 0.2 2.5 1 1 1 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain zf-CCCH_4 PF18044.1 EJP67807.1 - 8.9e-07 28.6 1.7 1.6e-06 27.7 1.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EJP67807.1 - 4.9e-06 26.4 5.2 8.8e-06 25.6 5.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EJP67807.1 - 7.4e-05 22.6 2.3 0.00013 21.7 2.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EJP67807.1 - 0.0024 18.1 0.2 0.0056 16.9 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 EJP67807.1 - 0.0054 17.4 2.2 0.023 15.4 2.2 2.3 1 0 0 1 1 1 1 Torus domain Channel_Tsx PF03502.13 EJP67807.1 - 0.02 14.7 0.6 0.036 13.8 0.6 1.4 1 0 0 1 1 1 0 Nucleoside-specific channel-forming protein, Tsx zf-CCCH_2 PF14608.6 EJP67807.1 - 0.12 12.9 0.9 0.2 12.2 0.9 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Translin PF01997.16 EJP67808.1 - 1.6e-46 158.9 0.0 1.9e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Translin family APC_N_CC PF16689.5 EJP67808.1 - 0.1 12.6 0.7 2.2 8.4 0.1 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Pro-kuma_activ PF09286.11 EJP67809.1 - 1.9e-14 54.2 0.0 4.6e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP67809.1 - 6.2e-08 32.3 0.0 9.8e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Chitin_synth_1 PF01644.17 EJP67810.1 - 2e-74 249.0 0.5 3.8e-74 248.1 0.5 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EJP67810.1 - 5.1e-28 96.8 0.0 1.1e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EJP67810.1 - 1.3e-21 76.8 3.7 4.1e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EJP67810.1 - 1.6e-09 38.0 1.2 1.6e-09 38.0 1.2 2.8 2 1 1 3 3 3 1 Glycosyl transferase family group 2 PRELI PF04707.14 EJP67811.1 - 1.9e-41 141.5 0.1 2.4e-41 141.2 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Pico_P2B PF01552.17 EJP67811.1 - 0.1 12.7 0.0 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Picornavirus 2B protein Peptidase_M24 PF00557.24 EJP67812.1 - 1.5e-45 155.5 0.4 1.9e-45 155.2 0.4 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PRK PF00485.18 EJP67813.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EJP67813.1 - 0.00065 20.3 0.0 0.002 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EJP67813.1 - 0.0047 15.9 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EJP67813.1 - 0.006 15.8 0.0 0.0093 15.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.12 EJP67813.1 - 0.0089 15.3 0.0 0.021 14.1 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 EJP67813.1 - 0.014 15.6 0.1 0.094 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EJP67813.1 - 0.031 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 EJP67813.1 - 0.033 13.2 0.1 0.056 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EJP67813.1 - 0.056 13.8 0.0 0.085 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 EJP67813.1 - 0.061 13.0 0.0 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA PF00004.29 EJP67813.1 - 0.077 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EJP67813.1 - 0.089 13.2 0.1 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EJP67813.1 - 0.11 12.2 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EJP67813.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.10 EJP67813.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 EJP67813.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AhpC-TSA_2 PF13911.6 EJP67814.1 - 4.1e-16 59.1 0.0 1e-15 57.8 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EJP67814.1 - 8.7e-07 28.9 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJP67814.1 - 0.0026 17.5 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin bZIP_1 PF00170.21 EJP67815.1 - 3.1e-06 27.2 3.9 5.4e-06 26.4 3.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor CDC45 PF02724.14 EJP67815.1 - 0.0046 15.3 2.1 0.0067 14.8 2.1 1.1 1 0 0 1 1 1 1 CDC45-like protein bZIP_2 PF07716.15 EJP67815.1 - 0.0098 16.0 3.9 0.018 15.1 3.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EJP67815.1 - 0.012 16.1 1.4 0.025 15.1 1.4 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Paramyxo_NS_C PF02725.14 EJP67815.1 - 0.081 13.0 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Non-structural protein C Dynamitin PF04912.14 EJP67815.1 - 0.099 11.9 0.8 0.14 11.4 0.8 1.1 1 0 0 1 1 1 0 Dynamitin Dynamin_N PF00350.23 EJP67816.1 - 2.8e-27 95.8 0.2 3e-26 92.5 0.0 2.6 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EJP67816.1 - 3.4e-22 79.0 0.3 9.9e-21 74.2 0.1 2.6 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EJP67816.1 - 0.00011 22.2 0.6 0.00097 19.2 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_27 PF13514.6 EJP67816.1 - 0.0048 16.5 0.1 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain RasGAP_C PF03836.15 EJP67816.1 - 0.2 11.8 1.4 2.3 8.4 0.1 2.5 2 0 0 2 2 2 0 RasGAP C-terminus DUF4795 PF16043.5 EJP67816.1 - 0.25 10.9 7.0 3.4 7.2 1.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) GED PF02212.18 EJP67816.1 - 0.46 10.7 5.4 1.9 8.7 0.1 3.0 3 0 0 3 3 3 0 Dynamin GTPase effector domain bZIP_1 PF00170.21 EJP67816.1 - 1.4 9.1 5.4 0.49 10.5 1.9 2.2 2 0 0 2 2 2 0 bZIP transcription factor AAA PF00004.29 EJP67817.1 - 1.4e-51 174.4 0.0 8.9e-39 132.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EJP67817.1 - 1.2e-10 41.7 0.0 0.00034 20.9 0.0 3.8 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EJP67817.1 - 1.8e-10 41.5 0.0 0.00059 20.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 EJP67817.1 - 6.5e-10 38.7 0.1 1.6e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain ATPase_2 PF01637.18 EJP67817.1 - 8.3e-09 35.7 0.1 0.071 13.0 0.0 4.1 2 2 1 4 4 4 2 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EJP67817.1 - 1.8e-08 34.5 0.0 0.0015 18.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EJP67817.1 - 5.2e-08 32.5 0.0 0.0036 16.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EJP67817.1 - 2.3e-07 30.9 0.0 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EJP67817.1 - 1.2e-06 28.8 0.0 0.00021 21.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EJP67817.1 - 2.1e-06 28.1 0.0 0.088 13.2 0.0 3.0 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 EJP67817.1 - 2.9e-06 27.1 0.2 0.1 12.3 0.1 2.9 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EJP67817.1 - 3.3e-06 27.3 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 EJP67817.1 - 9.9e-06 25.2 0.1 0.00047 19.9 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 EJP67817.1 - 1.2e-05 25.8 0.0 0.087 13.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EJP67817.1 - 1.4e-05 24.6 0.3 0.0063 15.9 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EJP67817.1 - 3.3e-05 23.5 0.5 0.078 12.5 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region NACHT PF05729.12 EJP67817.1 - 4.9e-05 23.3 0.4 0.15 12.0 0.0 3.6 4 0 0 4 4 3 1 NACHT domain IstB_IS21 PF01695.17 EJP67817.1 - 6.5e-05 22.7 0.0 0.45 10.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 EJP67817.1 - 0.00013 21.7 0.0 0.33 10.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 EJP67817.1 - 0.00016 21.5 0.0 0.028 14.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 EJP67817.1 - 0.00018 21.5 0.0 0.82 9.7 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EJP67817.1 - 0.00042 19.7 0.4 0.0083 15.5 0.2 2.3 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.22 EJP67817.1 - 0.00046 19.4 0.2 1 8.5 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.27 EJP67817.1 - 0.00051 20.6 0.0 0.36 11.3 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 EJP67817.1 - 0.0032 17.1 0.1 2.9 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EJP67817.1 - 0.0035 17.6 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EJP67817.1 - 0.0039 16.7 0.1 2.8 7.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 EJP67817.1 - 0.0073 16.3 0.2 3.8 7.5 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EJP67817.1 - 0.008 15.9 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EJP67817.1 - 0.0094 15.8 0.0 0.66 9.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 EJP67817.1 - 0.011 14.9 0.0 1.4 8.0 0.1 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EJP67817.1 - 0.017 15.5 0.0 7.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 EJP67817.1 - 0.024 13.8 0.1 0.83 8.8 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_3 PF07726.11 EJP67817.1 - 0.027 14.3 0.0 0.81 9.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EJP67817.1 - 0.036 13.8 0.1 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2075 PF09848.9 EJP67817.1 - 0.036 13.3 0.2 1.9 7.6 0.1 2.9 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EJP67817.1 - 0.038 14.3 0.0 0.84 10.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain TniB PF05621.11 EJP67817.1 - 0.13 11.7 0.1 8.9 5.7 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein DNA_pol3_delta2 PF13177.6 EJP67817.1 - 0.17 11.6 0.0 6.2 6.6 0.0 2.8 2 1 1 3 3 3 0 DNA polymerase III, delta subunit AAA_23 PF13476.6 EJP67817.1 - 0.2 12.2 0.1 9.2 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RasGEF PF00617.19 EJP67818.1 - 7.8e-47 159.8 0.1 1.3e-46 159.1 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EJP67818.1 - 5.5e-12 45.9 0.3 1.2e-11 44.7 0.3 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ribosomal_S2 PF00318.20 EJP67819.1 - 3.6e-24 85.2 0.1 2.8e-14 52.9 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EJP67819.1 - 7.3e-07 30.5 14.9 1.2e-06 29.7 14.9 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus MAGE_N PF12440.8 EJP67819.1 - 0.77 10.5 5.4 1.7 9.4 5.4 1.6 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal Ribosomal_S15 PF00312.22 EJP67820.1 - 6.7e-25 87.1 0.1 2.6e-24 85.2 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 vATP-synt_AC39 PF01992.16 EJP67821.1 - 7.5e-98 328.1 0.0 8.6e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.18 EJP67822.1 - 9.8e-78 260.8 0.2 9.8e-78 260.8 0.2 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EJP67822.1 - 1.3e-21 76.7 2.3 1.3e-21 76.7 2.3 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Tom5 PF10642.9 EJP67822.1 - 0.12 12.4 0.3 0.44 10.6 0.3 2.0 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DUF4604 PF15377.6 EJP67822.1 - 1.9 8.9 32.3 0.17 12.3 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Band_7 PF01145.25 EJP67823.1 - 2.7e-27 95.9 2.1 4.8e-27 95.1 2.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EJP67823.1 - 0.0073 16.3 0.4 0.032 14.3 0.4 2.1 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 EJP67823.1 - 0.012 15.3 0.3 0.022 14.5 0.3 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family ANAPC10 PF03256.16 EJP67824.1 - 1.2e-47 161.9 0.1 2e-47 161.2 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Fringe PF02434.16 EJP67825.1 - 4.4e-05 23.0 2.0 0.0016 17.9 2.0 2.7 1 1 0 1 1 1 1 Fringe-like DUF669 PF05037.13 EJP67825.1 - 0.18 11.9 0.2 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF669) FAM76 PF16046.5 EJP67826.1 - 0.021 14.2 6.9 0.025 13.9 6.9 1.1 1 0 0 1 1 1 0 FAM76 protein Prefoldin_2 PF01920.20 EJP67826.1 - 0.023 14.7 1.5 0.034 14.1 1.5 1.3 1 0 0 1 1 1 0 Prefoldin subunit Mis12 PF05859.12 EJP67826.1 - 0.086 12.9 2.1 0.12 12.4 2.1 1.2 1 0 0 1 1 1 0 Mis12 protein T2SSB PF16537.5 EJP67826.1 - 0.11 12.2 0.4 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system protein B ATG16 PF08614.11 EJP67826.1 - 0.42 10.8 15.5 0.18 12.0 13.4 1.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 EJP67826.1 - 0.84 9.8 14.3 2.2 8.4 2.3 2.8 1 1 2 3 3 3 0 TolA binding protein trimerisation Asp PF00026.23 EJP67827.1 - 2.6e-56 191.3 0.0 3.1e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP67827.1 - 5.1e-11 43.1 0.1 3.1e-09 37.3 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EJP67827.1 - 1.1e-06 28.5 0.0 2.7e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EJP67827.1 - 0.0029 18.2 0.1 2 9.1 0.1 3.3 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EJP67827.1 - 0.019 15.5 0.1 3 8.5 0.1 3.1 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease HSP70 PF00012.20 EJP67828.1 - 2.8e-52 177.7 20.8 2.8e-50 171.2 6.5 3.9 1 1 2 4 4 4 2 Hsp70 protein DUF908 PF06012.12 EJP67828.1 - 0.46 9.9 17.4 0.0074 15.7 3.8 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF3446 PF11928.8 EJP67828.1 - 0.49 10.7 10.8 3.6 8.0 0.5 3.0 2 0 0 2 2 2 0 Early growth response N-terminal domain FlxA PF14282.6 EJP67829.1 - 0.0082 16.1 13.5 0.13 12.3 12.1 2.8 1 1 0 1 1 1 1 FlxA-like protein GrpE PF01025.19 EJP67829.1 - 4.3 7.0 11.6 2 8.0 9.0 1.8 1 1 1 2 2 2 0 GrpE CENP-W PF15510.6 EJP67830.1 - 0.00015 21.9 0.0 0.00019 21.6 0.0 1.1 1 0 0 1 1 1 1 CENP-W protein CBFD_NFYB_HMF PF00808.23 EJP67830.1 - 0.0037 17.5 0.0 0.0051 17.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4111 PF13427.6 EJP67830.1 - 0.085 13.0 0.1 0.098 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Prefoldin_2 PF01920.20 EJP67831.1 - 2.1e-24 85.5 8.9 3.3e-24 84.9 8.9 1.3 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.11 EJP67831.1 - 0.04 14.5 7.5 1.4 9.5 1.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal THRAP3_BCLAF1 PF15440.6 EJP67831.1 - 0.041 12.9 3.4 0.047 12.7 3.4 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family eIF-4B PF06273.11 EJP67831.1 - 4.6 6.2 8.2 5.5 5.9 8.2 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Bac_small_YrzI PF09501.10 EJP67831.1 - 5.5 7.2 7.8 7 6.9 0.1 3.3 2 1 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) FIN1 PF17300.2 EJP67831.1 - 6.4 6.2 10.1 7.7 5.9 10.1 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 DUF5320 PF17253.2 EJP67831.1 - 8.7 7.5 7.1 29 5.8 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) ABC2_membrane PF01061.24 EJP67832.1 - 0.22 10.9 3.3 0.11 11.8 0.8 1.7 1 1 1 2 2 2 0 ABC-2 type transporter MFS_1 PF07690.16 EJP67833.1 - 1.2e-27 96.8 32.2 2.8e-27 95.6 32.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP67833.1 - 1.8e-16 60.1 3.2 1.8e-16 60.1 3.2 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP67833.1 - 4.9e-15 55.0 6.8 5.9e-15 54.7 6.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YrhK PF14145.6 EJP67833.1 - 0.07 13.0 2.8 0.76 9.7 0.5 2.8 2 0 0 2 2 2 0 YrhK-like protein DUF3522 PF12036.8 EJP67833.1 - 2.7 8.2 9.4 0.53 10.6 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) OATP PF03137.20 EJP67833.1 - 5.8 5.1 12.0 0.045 12.0 2.9 2.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MMS19_N PF14500.6 EJP67834.1 - 0.034 13.7 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Annexin_like PF18411.1 EJP67834.1 - 0.15 12.4 0.0 0.6 10.4 0.0 1.9 2 0 0 2 2 2 0 Annexin-like domain Aminotran_1_2 PF00155.21 EJP67835.1 - 7e-37 127.4 0.0 9.2e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 EJP67835.1 - 0.00014 20.7 0.0 0.00038 19.3 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 EJP67835.1 - 0.00028 20.0 0.0 0.00082 18.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EJP67835.1 - 0.0003 19.5 0.0 0.00069 18.2 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 EJP67835.1 - 0.00053 18.8 0.1 0.00073 18.3 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EJP67835.1 - 0.00097 18.5 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SHMT PF00464.19 EJP67835.1 - 0.012 14.2 0.1 0.017 13.7 0.1 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase ketoacyl-synt PF00109.26 EJP67836.1 - 8.6e-64 215.5 0.4 2e-63 214.3 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EJP67836.1 - 8.4e-60 202.9 0.0 1.5e-59 202.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EJP67836.1 - 1.5e-57 195.1 0.1 2.6e-57 194.3 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EJP67836.1 - 1.9e-56 190.8 4.3 2.5e-56 190.4 2.3 2.3 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 EJP67836.1 - 6.3e-33 113.3 0.7 1.9e-32 111.8 0.7 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EJP67836.1 - 8.6e-27 93.8 0.1 2.5e-26 92.3 0.0 1.9 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EJP67836.1 - 6.5e-14 52.1 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP67836.1 - 1.1e-12 48.6 0.1 8.6e-12 45.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP67836.1 - 1.3e-10 41.3 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67836.1 - 5e-07 30.3 0.0 2.3e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 EJP67836.1 - 1.2e-06 28.4 0.8 2.3e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EJP67836.1 - 1.3e-06 28.1 5.2 2.1e-06 27.3 1.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 EJP67836.1 - 2.3e-05 24.6 0.0 0.00014 22.1 0.0 2.5 3 0 0 3 3 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EJP67836.1 - 5.3e-05 22.7 0.5 0.00011 21.6 0.5 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DREV PF05219.12 EJP67836.1 - 9.2e-05 21.7 0.0 0.00039 19.6 0.0 2.0 2 0 0 2 2 2 1 DREV methyltransferase Ubie_methyltran PF01209.18 EJP67836.1 - 0.00049 19.5 0.1 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 EJP67836.1 - 0.00077 19.4 0.1 0.0022 18.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 EJP67837.1 - 5.6e-42 143.9 32.7 5.6e-42 143.9 32.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP67837.1 - 1.7e-14 53.5 1.6 1.7e-14 53.5 1.6 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 EJP67837.1 - 2.3e-06 26.7 5.4 7.9e-06 24.9 2.6 2.5 2 0 0 2 2 2 1 POT family MFS_4 PF06779.14 EJP67837.1 - 7.7e-06 25.4 7.6 2.9e-05 23.6 1.2 2.4 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 EJP67839.1 - 5.8e-37 127.4 38.5 4.7e-35 121.2 39.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP67839.1 - 6.6e-06 25.2 5.0 6.6e-06 25.2 5.0 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter DUF5379 PF17350.2 EJP67839.1 - 1.3 9.3 5.0 2.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5379) NDUFA12 PF05071.16 EJP67840.1 - 4.1e-09 37.2 0.0 4.1e-09 37.2 0.0 2.3 1 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 MFS_1 PF07690.16 EJP67841.1 - 1e-36 126.6 31.6 1e-36 126.6 31.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP67841.1 - 4.6e-09 35.7 7.1 4.6e-09 35.7 7.1 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter CH PF00307.31 EJP67842.1 - 1e-13 51.4 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EJP67842.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain SET PF00856.28 EJP67843.1 - 5e-08 33.5 0.0 3.7e-07 30.7 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_9 PF13371.6 EJP67843.1 - 0.55 10.4 3.5 1.2 9.3 3.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Glucosamine_iso PF01182.20 EJP67844.1 - 6.9e-70 235.4 0.0 8.6e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SPX PF03105.19 EJP67845.1 - 0.00049 20.1 0.8 0.00049 20.1 0.8 2.1 2 0 0 2 2 2 1 SPX domain MIP-T3_C PF17749.1 EJP67845.1 - 0.02 14.8 1.3 0.049 13.6 1.3 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Snf7 PF03357.21 EJP67846.1 - 6.5e-25 87.7 7.8 6.5e-25 87.7 7.8 1.8 2 0 0 2 2 2 1 Snf7 Effector_1 PF04518.12 EJP67846.1 - 0.052 12.6 1.4 0.095 11.8 1.4 1.4 1 0 0 1 1 1 0 Effector from type III secretion system GAS PF13851.6 EJP67846.1 - 1.1 8.5 10.7 0.12 11.7 4.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EJP67846.1 - 1.2 9.2 9.8 0.17 11.9 5.0 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ribosomal_60s PF00428.19 EJP67846.1 - 9.8 6.8 12.0 1.1 9.9 6.6 2.1 2 1 1 3 3 3 0 60s Acidic ribosomal protein CS PF04969.16 EJP67847.1 - 1e-08 36.0 0.1 1.6e-08 35.4 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF4202 PF13875.6 EJP67847.1 - 0.067 13.1 0.4 0.092 12.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) RRM_1 PF00076.22 EJP67848.1 - 3.5e-16 58.8 0.0 5.5e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EJP67848.1 - 1.7e-08 34.9 7.8 1.7e-08 34.9 7.8 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EJP67848.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif TipE PF16972.5 EJP67848.1 - 0.081 12.1 1.1 0.12 11.5 1.1 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE ABC_membrane PF00664.23 EJP67849.1 - 2.7e-43 148.6 5.2 3.3e-43 148.3 5.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Fungal_trans PF04082.18 EJP67850.1 - 0.00036 19.6 0.0 0.00069 18.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Unstab_antitox PF09720.10 EJP67850.1 - 0.15 12.2 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Putative addiction module component p450 PF00067.22 EJP67851.1 - 1.1e-48 166.2 0.0 1.4e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 EJP67852.1 - 2.6e-21 76.4 0.0 3e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EJP67852.1 - 0.0045 16.6 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EJP67852.1 - 0.026 13.5 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EJP67852.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EJP67852.1 - 0.19 12.2 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 EJP67853.1 - 9.2e-54 182.5 0.6 1.2e-53 182.1 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP67853.1 - 1.2e-46 158.6 0.3 1.5e-46 158.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP67853.1 - 1.5e-10 41.3 0.3 2e-10 40.8 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP67853.1 - 0.0037 16.8 0.2 0.066 12.7 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 EJP67853.1 - 0.0046 16.8 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TrmE_N PF10396.9 EJP67853.1 - 0.0079 16.5 0.3 0.12 12.7 0.0 2.3 1 1 1 2 2 2 1 GTP-binding protein TrmE N-terminus Peripla_BP_6 PF13458.6 EJP67853.1 - 0.025 14.2 0.8 0.049 13.3 0.7 1.5 2 0 0 2 2 2 0 Periplasmic binding protein 2-Hacid_dh_C PF02826.19 EJP67853.1 - 0.052 12.9 0.1 0.079 12.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1772 PF08592.11 EJP67854.1 - 7.3e-22 78.2 1.1 1.1e-21 77.6 1.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2227 PF09988.9 EJP67854.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) DUF5084 PF16894.5 EJP67854.1 - 0.11 13.0 1.2 0.11 12.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5084) OapA_N PF08525.11 EJP67854.1 - 8.1 6.5 7.9 20 5.2 0.5 3.3 3 0 0 3 3 3 0 Opacity-associated protein A N-terminal motif p450 PF00067.22 EJP67855.1 - 7.6e-24 84.3 0.0 4.2e-23 81.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Enterotoxin_a PF01375.17 EJP67856.1 - 1.5e-21 77.1 0.1 2.4e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain DUF2993 PF11209.8 EJP67856.1 - 0.027 14.7 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) POT1PC PF16686.5 EJP67856.1 - 0.029 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Pectate_lyase_3 PF12708.7 EJP67858.1 - 3.8e-18 66.1 14.0 7.3e-12 45.6 0.9 3.7 5 0 0 5 5 5 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EJP67858.1 - 0.002 17.8 0.1 0.0059 16.3 0.1 1.8 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase Varsurf_PPLC PF03490.13 EJP67858.1 - 0.084 12.8 1.0 0.22 11.5 0.2 2.1 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C VTC PF09359.10 EJP67859.1 - 2.2e-80 270.0 1.2 4e-80 269.2 1.2 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EJP67859.1 - 9.4e-11 42.0 4.1 9.4e-11 42.0 4.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EJP67859.1 - 6.4e-08 32.9 4.1 9.5e-05 22.5 0.1 4.6 2 2 2 5 5 5 2 SPX domain EamA PF00892.20 EJP67859.1 - 0.12 12.5 0.3 0.25 11.5 0.3 1.4 1 0 0 1 1 1 0 EamA-like transporter family Aldo_ket_red PF00248.21 EJP67861.1 - 1.1e-74 251.3 0.0 1.2e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C97 PF05903.14 EJP67862.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 EJP67862.1 - 0.0036 17.7 0.3 0.0069 16.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF778) DUF4105 PF13387.6 EJP67862.1 - 0.047 13.3 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) LRAT PF04970.13 EJP67862.1 - 0.076 13.3 1.3 1.8 8.9 1.3 2.3 1 1 0 1 1 1 0 Lecithin retinol acyltransferase MASE2 PF05230.11 EJP67863.1 - 0.003 17.6 0.8 0.57 10.3 0.1 2.9 2 0 0 2 2 2 2 MASE2 domain DAP_B PF07930.12 EJP67864.1 - 5.8e-70 235.0 0.0 8.3e-70 234.5 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 EJP67864.1 - 1.1e-43 149.8 0.0 1.6e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 EJP67865.1 - 3e-17 62.6 40.1 3e-17 62.6 40.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.6 EJP67865.1 - 0.029 14.6 1.5 0.062 13.6 0.1 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AB Sugar_tr PF00083.24 EJP67866.1 - 4.9e-110 368.5 14.5 6.1e-110 368.2 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP67866.1 - 1.3e-15 57.2 28.8 1.8e-12 46.9 7.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EJP67866.1 - 1.5e-06 26.9 3.4 2.2e-06 26.3 2.0 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_5 PF05631.14 EJP67866.1 - 0.00046 19.2 6.3 0.011 14.6 0.8 2.2 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM Glyco_hydro_20 PF00728.22 EJP67867.1 - 0.023 14.1 0.0 0.026 13.9 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain PhzC-PhzF PF02567.16 EJP67868.1 - 3.5e-42 144.8 0.1 1.5e-41 142.7 0.1 1.8 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 EJP67868.1 - 0.032 13.3 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 Proline racemase DJ-1_PfpI PF01965.24 EJP67869.1 - 5.6e-11 42.5 0.0 6.5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family POT1 PF02765.17 EJP67871.1 - 0.1 12.4 1.4 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 Cu-oxidase_2 PF07731.14 EJP67872.1 - 1.5e-36 125.2 8.6 1.5e-36 125.1 0.0 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EJP67872.1 - 2.4e-34 117.9 4.4 2.7e-34 117.7 2.6 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EJP67872.1 - 6.6e-31 107.6 0.4 2.1e-30 106.0 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase TauD PF02668.16 EJP67873.1 - 5.8e-38 131.2 0.1 9.3e-38 130.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EJP67874.1 - 5.4e-12 45.3 24.7 5.4e-12 45.3 24.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EJP67874.1 - 4.2e-09 36.3 3.3 8.9e-09 35.3 3.3 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EJP67874.1 - 0.00076 18.4 4.1 0.00076 18.4 4.1 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3925 PF13063.6 EJP67874.1 - 0.067 13.4 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Pkinase PF00069.25 EJP67875.1 - 1.2e-22 80.5 0.0 5e-21 75.3 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67875.1 - 1.3e-08 34.4 0.1 4.6e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase GATase_2 PF00310.21 EJP67877.1 - 1.5e-183 610.3 0.0 2.1e-183 609.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EJP67877.1 - 3.1e-155 516.9 0.0 5.3e-155 516.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EJP67877.1 - 5.9e-112 373.7 0.0 9.3e-111 369.8 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EJP67877.1 - 1.3e-85 285.8 2.1 2.1e-85 285.1 2.1 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EJP67877.1 - 7.5e-23 81.2 0.1 6.7e-22 78.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EJP67877.1 - 2e-21 75.9 0.1 4.5e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 EJP67877.1 - 6.8e-08 33.0 0.1 0.00067 20.2 0.1 3.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP67877.1 - 7.9e-08 32.4 0.1 3e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP67877.1 - 4.3e-07 29.9 1.5 0.0015 18.2 0.3 2.9 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EJP67877.1 - 9.8e-06 25.1 0.2 1.9e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EJP67877.1 - 6.7e-05 22.4 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EJP67877.1 - 7e-05 22.2 0.4 0.15 11.3 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP67877.1 - 0.00012 21.0 0.2 0.00025 19.9 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EJP67877.1 - 0.00027 20.3 0.2 0.05 12.9 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EJP67877.1 - 0.00075 18.7 0.0 0.0022 17.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EJP67877.1 - 0.0017 17.7 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EJP67877.1 - 0.0024 18.3 1.2 3.4 8.1 0.1 3.4 3 0 0 3 3 3 1 Putative NAD(P)-binding FMO-like PF00743.19 EJP67877.1 - 0.0065 15.0 0.1 0.77 8.1 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like FMN_dh PF01070.18 EJP67877.1 - 0.009 15.1 1.0 0.15 11.1 1.1 2.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Thi4 PF01946.17 EJP67877.1 - 0.017 14.4 0.1 0.053 12.7 0.1 1.8 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EJP67877.1 - 0.22 10.6 0.3 1.3 7.9 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EJP67877.1 - 0.44 9.6 3.2 0.22 10.5 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans_2 PF11951.8 EJP67878.1 - 5.5e-26 91.3 1.7 3.3e-15 55.8 0.1 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67878.1 - 7.9e-05 22.7 12.3 0.00014 21.9 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 EJP67879.1 - 7.2e-52 177.2 0.4 8.3e-52 177.0 0.4 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP67879.1 - 1.2e-10 41.5 0.6 2.7e-10 40.3 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EJP67879.1 - 9.4e-08 31.8 0.0 3.2e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EJP67879.1 - 2.1e-07 30.4 0.1 3.4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EJP67879.1 - 3.5e-07 30.1 0.0 3.7e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP67879.1 - 2.1e-05 23.4 0.1 0.0013 17.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EJP67879.1 - 3.5e-05 23.1 0.0 5.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EJP67879.1 - 0.00015 21.0 1.7 0.00016 20.9 0.7 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EJP67879.1 - 0.00022 20.4 0.1 0.00058 19.0 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EJP67879.1 - 0.00055 19.3 0.0 0.0014 17.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP67879.1 - 0.014 14.7 0.0 0.93 8.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP67879.1 - 0.015 15.3 0.2 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AA_permease_2 PF13520.6 EJP67880.1 - 1.7e-43 149.0 48.7 5.7e-43 147.3 49.0 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP67880.1 - 5.1e-21 74.8 41.8 7e-21 74.4 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2897 PF11446.8 EJP67880.1 - 2.1 8.3 5.0 1.8 8.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2897) Apc15p PF05841.11 EJP67881.1 - 1.8e-19 70.8 0.7 1.8e-19 70.8 0.7 3.6 3 1 0 3 3 3 1 Apc15p protein Use1 PF09753.9 EJP67882.1 - 0.0024 17.7 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 CHZ PF09649.10 EJP67883.1 - 4.2e-14 51.7 1.2 4.2e-14 51.7 1.2 2.8 3 1 0 3 3 3 1 Histone chaperone domain CHZ BUD22 PF09073.10 EJP67883.1 - 4.6 6.5 27.3 5.1 6.3 27.3 1.0 1 0 0 1 1 1 0 BUD22 WSC PF01822.19 EJP67885.1 - 2.5e-32 110.9 34.3 4.1e-20 71.7 10.5 4.3 5 0 0 5 5 5 2 WSC domain Glyco_hydro_31 PF01055.26 EJP67886.1 - 2.3e-96 323.7 5.3 3e-96 323.3 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 EJP67886.1 - 0.031 14.6 0.0 0.056 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Ank_4 PF13637.6 EJP67887.1 - 6.8e-09 36.1 0.1 2.8e-07 30.9 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP67887.1 - 3.7e-06 27.4 0.0 4.2e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP67887.1 - 6.7e-05 23.1 0.0 0.00025 21.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EJP67887.1 - 7e-05 23.1 1.3 0.0091 16.4 0.0 3.1 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EJP67887.1 - 0.0082 16.6 0.0 5.9 7.8 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeat Complex1_LYR PF05347.15 EJP67891.1 - 4.2e-21 74.7 4.9 5.8e-21 74.3 4.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EJP67891.1 - 4.1e-06 27.4 2.9 4.7e-06 27.3 2.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EJP67891.1 - 0.0012 19.3 0.5 0.0015 19.1 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DASH_Spc34 PF08657.10 EJP67891.1 - 0.011 15.6 1.0 0.014 15.2 1.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Mis14 PF08641.12 EJP67891.1 - 0.013 15.8 0.6 0.016 15.5 0.6 1.2 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Glutaredoxin2_C PF04399.13 EJP67891.1 - 0.032 14.1 0.3 0.037 13.9 0.3 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain VitD-bind_III PF09164.10 EJP67891.1 - 0.15 12.1 0.4 0.24 11.4 0.4 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III WD40 PF00400.32 EJP67892.1 - 2.2e-08 34.6 6.0 0.087 13.7 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP67892.1 - 0.00092 19.5 0.0 0.92 9.8 0.0 4.0 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EJP67892.1 - 0.003 18.0 0.1 5.9 7.5 0.0 4.5 4 1 1 5 5 5 1 PQQ-like domain PQQ_2 PF13360.6 EJP67892.1 - 0.0068 16.0 0.6 0.057 13.0 0.4 2.6 2 1 0 2 2 2 1 PQQ-like domain PALB2_WD40 PF16756.5 EJP67892.1 - 0.033 13.1 0.2 0.58 9.0 0.0 2.3 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Cas9-BH PF16593.5 EJP67892.1 - 0.11 12.3 2.9 0.21 11.3 2.9 1.4 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 CLN3 PF02487.17 EJP67895.1 - 1.1e-45 156.4 2.9 1.3e-45 156.2 2.9 1.0 1 0 0 1 1 1 1 CLN3 protein WW PF00397.26 EJP67896.1 - 3.7e-06 26.9 7.0 8.3e-06 25.8 7.0 1.6 1 0 0 1 1 1 1 WW domain KinB_sensor PF16767.5 EJP67896.1 - 0.34 11.4 2.2 0.31 11.5 0.8 1.5 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB TPR_2 PF07719.17 EJP67896.1 - 0.46 10.7 5.3 3.8 7.9 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HCMV_UL139 PF12507.8 EJP67896.1 - 0.5 10.8 3.9 1.4 9.4 3.9 1.7 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF2853 PF11015.8 EJP67896.1 - 1 10.1 4.4 19 6.0 4.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2853) TPR_11 PF13414.6 EJP67896.1 - 1.7 8.4 6.8 8.5 6.2 0.3 2.5 2 0 0 2 2 2 0 TPR repeat Na_trans_assoc PF06512.13 EJP67896.1 - 2.2 8.5 5.5 3.3 8.0 5.5 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated TPR_10 PF13374.6 EJP67896.1 - 2.2 8.3 6.6 14 5.7 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4404 PF14357.6 EJP67896.1 - 7.7 7.2 5.2 9.4 7.0 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Ank_2 PF12796.7 EJP67897.1 - 3.1e-35 120.6 0.8 2.7e-12 47.1 0.0 5.7 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP67897.1 - 1.6e-24 85.9 1.8 6.2e-05 23.5 0.0 6.9 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP67897.1 - 9.6e-22 76.8 3.6 9.9e-05 22.6 0.1 7.7 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP67897.1 - 2.4e-20 70.4 5.9 0.0013 19.0 0.0 10.6 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 EJP67897.1 - 7.9e-16 57.7 0.6 0.0038 17.6 0.0 6.9 8 0 0 8 8 8 4 Ankyrin repeat Peptidase_C14 PF00656.22 EJP67898.1 - 1.8e-60 205.0 0.0 2.2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EJP67898.1 - 0.12 12.3 0.1 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Na_Ca_ex PF01699.24 EJP67899.1 - 7e-20 71.5 31.2 2.2e-10 40.7 10.0 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Acetyltransf_1 PF00583.25 EJP67900.1 - 0.0022 18.2 0.1 0.0058 16.9 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP67900.1 - 0.0053 17.2 0.1 0.01 16.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP67900.1 - 0.081 13.0 0.0 0.78 9.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PALP PF00291.25 EJP67901.1 - 9.9e-58 195.9 2.2 2e-57 194.9 2.2 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AbiEii PF08843.11 EJP67903.1 - 1.2e-05 25.4 0.1 2e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system HrcA PF01628.21 EJP67903.1 - 0.029 14.3 0.2 0.05 13.5 0.0 1.4 2 0 0 2 2 2 0 HrcA protein C terminal domain CN_hydrolase PF00795.22 EJP67905.1 - 1.1e-36 126.6 0.0 1.5e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EJP67905.1 - 1.1e-23 83.6 0.0 3.9e-23 81.8 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Fungal_trans PF04082.18 EJP67906.1 - 7.7e-11 41.5 0.0 1.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP67906.1 - 8.7e-08 32.2 9.4 1.9e-07 31.1 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.18 EJP67907.1 - 2e-58 197.6 0.0 2.8e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EJP67907.1 - 1e-31 109.3 0.0 1.8e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal TRAUB PF08164.12 EJP67908.1 - 3.8e-30 104.2 0.7 3.8e-30 104.2 0.7 2.8 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EJP67908.1 - 8.9e-27 94.5 1.6 8.9e-27 94.5 1.6 3.5 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor FANCL_C PF11793.8 EJP67908.1 - 0.026 14.7 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain ParA PF10609.9 EJP67909.1 - 1.1e-95 319.8 0.2 1.2e-95 319.6 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EJP67909.1 - 1.5e-10 41.2 0.0 7.6e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EJP67909.1 - 1.6e-09 37.9 0.1 2.3e-07 30.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 EJP67909.1 - 0.00016 21.2 0.0 0.15 11.5 0.0 2.4 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EJP67909.1 - 0.00017 21.0 0.0 0.00023 20.5 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EJP67909.1 - 0.0014 17.9 0.3 0.025 13.8 0.0 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 EJP67909.1 - 0.004 17.0 0.4 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 EJP67909.1 - 0.0092 15.5 0.3 0.079 12.4 0.1 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EJP67909.1 - 0.034 13.7 0.4 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain Tudor_3 PF18115.1 EJP67910.1 - 6.5e-06 25.9 0.1 1.1e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EJP67910.1 - 0.00056 19.9 0.1 0.00093 19.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 EJP67910.1 - 0.012 15.4 0.1 0.025 14.4 0.1 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain IL11 PF07400.11 EJP67910.1 - 0.13 11.9 0.4 0.21 11.2 0.4 1.4 1 0 0 1 1 1 0 Interleukin 11 FlxA PF14282.6 EJP67910.1 - 0.14 12.2 0.6 0.34 10.9 0.6 1.6 1 0 0 1 1 1 0 FlxA-like protein TCO89 PF10452.9 EJP67911.1 - 0.002 17.2 0.2 0.002 17.2 0.2 3.5 3 1 0 3 3 3 2 TORC1 subunit TCO89 ABC1 PF03109.16 EJP67912.1 - 8.6e-23 80.8 0.0 6.6e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 EJP67912.1 - 0.012 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EJP67912.1 - 0.18 11.4 0.0 0.78 9.3 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Cyto_heme_lyase PF01265.17 EJP67913.1 - 3.8e-122 407.5 0.5 4.3e-122 407.3 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DbpA PF03880.15 EJP67914.1 - 0.0053 16.7 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_1 PF00076.22 EJP67914.1 - 0.037 13.9 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Beta-lactamase PF00144.24 EJP67915.1 - 1.1e-44 153.1 1.8 1.7e-44 152.4 1.8 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EJP67915.1 - 3e-05 24.4 0.0 5.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) BUD22 PF09073.10 EJP67916.1 - 4.6e-100 336.0 41.7 9.2e-100 335.0 41.7 1.4 1 1 0 1 1 1 1 BUD22 ALMS_repeat PF18727.1 EJP67916.1 - 0.35 10.8 2.0 0.84 9.6 2.0 1.6 1 0 0 1 1 1 0 Alstrom syndrome repeat Mito_carr PF00153.27 EJP67917.1 - 2.8e-52 174.6 5.5 2.7e-18 65.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJP67917.1 - 0.038 13.1 2.3 0.57 9.3 0.0 2.6 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Rad4 PF03835.15 EJP67918.1 - 1.2e-29 102.9 0.1 3e-29 101.6 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EJP67918.1 - 1.1e-27 96.2 0.2 4.5e-27 94.3 0.2 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EJP67918.1 - 9e-22 76.7 0.1 2.5e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EJP67918.1 - 8.8e-19 68.2 0.4 8.8e-19 68.2 0.4 3.9 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EJP67918.1 - 0.00085 19.8 0.7 0.01 16.3 0.7 2.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily ABC_tran PF00005.27 EJP67919.1 - 2.8e-48 163.9 0.2 3.5e-26 92.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EJP67919.1 - 5.9e-26 91.4 43.7 2.8e-17 62.9 21.2 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 EJP67919.1 - 1.6e-24 87.2 2.2 1.4e-06 28.3 0.0 5.5 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP67919.1 - 2.3e-09 36.8 0.5 0.00034 20.3 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 EJP67919.1 - 2e-08 33.9 2.7 0.12 11.8 0.1 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EJP67919.1 - 3.6e-06 26.9 0.0 0.11 12.2 0.1 3.9 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EJP67919.1 - 3.7e-06 27.6 9.1 0.0088 16.6 0.1 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EJP67919.1 - 4.9e-05 23.3 1.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 EJP67919.1 - 0.0012 18.5 0.2 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJP67919.1 - 0.0029 18.0 0.2 0.83 10.0 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF4162 PF13732.6 EJP67919.1 - 0.0036 18.0 0.0 0.21 12.3 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_30 PF13604.6 EJP67919.1 - 0.0044 16.8 2.9 1.7 8.3 0.2 2.8 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 EJP67919.1 - 0.012 14.9 0.2 2.7 7.2 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin MeaB PF03308.16 EJP67919.1 - 0.018 14.0 0.8 0.091 11.7 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EJP67919.1 - 0.033 14.4 0.6 3.5 7.9 0.5 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EJP67919.1 - 0.068 12.8 0.3 12 5.5 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EJP67919.1 - 0.1 12.8 0.1 16 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 EJP67919.1 - 0.16 11.7 0.2 19 4.9 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_18 PF13238.6 EJP67919.1 - 0.21 12.1 0.1 12 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MecA PF05389.12 EJP67919.1 - 0.49 10.0 3.2 0.84 9.2 3.2 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF87 PF01935.17 EJP67919.1 - 1.8 8.6 8.0 6.3 6.8 0.0 3.5 4 0 0 4 4 3 0 Helicase HerA, central domain PHY PF00360.20 EJP67920.1 - 2.6e-27 95.3 0.0 5.6e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EJP67920.1 - 4.6e-21 75.4 0.3 1.3e-20 74.0 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EJP67920.1 - 1.9e-16 60.2 0.2 1.7e-15 57.1 0.2 2.6 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 EJP67920.1 - 2.4e-12 47.7 0.0 8.7e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 EJP67920.1 - 3.8e-12 46.1 0.8 1.8e-11 43.9 0.8 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EJP67920.1 - 2.4e-10 41.0 0.0 8.1e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 EJP67920.1 - 0.00035 20.5 0.0 0.0012 18.8 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EJP67920.1 - 0.0094 15.8 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lipoprotein_16 PF03923.13 EJP67920.1 - 0.16 11.6 1.0 0.35 10.5 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized lipoprotein Copper-fist PF00649.18 EJP67921.1 - 2.8e-14 52.3 4.4 3.8e-13 48.7 0.9 4.0 2 1 2 4 4 4 2 Copper fist DNA binding domain Fungal_trans PF04082.18 EJP67922.1 - 4.4e-06 25.9 0.2 0.0018 17.3 0.1 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF1741 PF08427.10 EJP67922.1 - 0.0062 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Ribonuc_L-PSP PF01042.21 EJP67923.1 - 6.9e-18 64.8 0.0 9.1e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.11 EJP67923.1 - 0.097 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 NOGCT (NUC087) domain Abhydrolase_1 PF00561.20 EJP67924.1 - 7.4e-11 42.2 0.1 1.2e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP67924.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Amidase PF01425.21 EJP67925.1 - 2.1e-76 257.7 2.7 4.3e-76 256.7 2.7 1.5 1 1 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 EJP67926.1 - 5.2e-35 121.1 0.0 1.9e-34 119.3 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP67926.1 - 1.8e-33 115.6 0.0 3.3e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP67926.1 - 4.5e-08 33.2 0.7 8.9e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EJP67926.1 - 0.0083 15.6 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family p450 PF00067.22 EJP67927.1 - 2.3e-58 198.1 0.0 3e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 EJP67928.1 - 4.8e-45 153.9 0.1 5.7e-45 153.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP67928.1 - 1.9e-37 128.6 0.0 2.3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP67928.1 - 1.3e-07 31.7 0.1 1.8e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 KR domain AA_permease PF00324.21 EJP67929.1 - 3.6e-93 312.7 37.7 4.5e-93 312.4 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP67929.1 - 5.9e-20 71.5 41.2 7.4e-20 71.2 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 EJP67930.1 - 2.2e-08 34.1 10.0 3.4e-08 33.5 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP67930.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain MafB19-deam PF14437.6 EJP67930.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 MafB19-like deaminase Methyltransf_25 PF13649.6 EJP67931.1 - 1.6e-07 31.9 0.0 2.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP67931.1 - 4.3e-05 24.2 0.0 0.00023 21.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP67931.1 - 0.0012 18.7 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67931.1 - 0.0013 19.3 0.0 0.0024 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP67931.1 - 0.051 13.4 0.0 0.082 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain UCH_1 PF13423.6 EJP67932.1 - 2e-101 339.8 0.1 3.3e-101 339.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EJP67932.1 - 7.1e-23 82.0 0.0 1.5e-22 80.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 EJP67932.1 - 2.9e-05 23.7 0.0 5.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 EJP67932.1 - 0.0075 16.5 0.1 0.44 10.9 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain FlaG PF03646.15 EJP67932.1 - 0.077 13.2 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 FlaG protein SHNi-TPR PF10516.9 EJP67932.1 - 0.19 11.2 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 SHNi-TPR CK_II_beta PF01214.18 EJP67933.1 - 3.8e-74 248.4 0.0 5.5e-74 247.9 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 EJP67933.1 - 0.25 9.9 1.5 0.36 9.3 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 EJP67933.1 - 2.4 8.6 11.8 3.4 8.1 2.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cupin_8 PF13621.6 EJP67934.1 - 5.7e-26 91.8 0.0 6.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EJP67934.1 - 0.0063 16.0 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EJP67934.1 - 0.015 15.7 0.0 0.06 13.8 0.0 2.1 2 1 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 EJP67934.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ran-binding PF05508.11 EJP67935.1 - 2.8e-102 341.9 0.3 2.8e-102 341.9 0.3 1.4 2 0 0 2 2 2 1 RanGTP-binding protein Ribosomal_L50 PF10501.9 EJP67935.1 - 0.076 13.2 0.2 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal subunit 39S GTP_EFTU PF00009.27 EJP67936.1 - 4.8e-43 147.0 0.0 8.4e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EJP67936.1 - 4.6e-28 97.8 0.1 1.5e-27 96.1 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EJP67936.1 - 4.4e-09 36.6 0.1 1.2e-08 35.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EJP67936.1 - 0.0012 18.9 0.1 0.0063 16.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase PEPCK_ATP PF01293.20 EJP67937.1 - 2.6e-214 712.2 0.0 3.1e-214 711.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.6 EJP67937.1 - 0.091 12.3 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EJP67937.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 EJP67938.1 - 2.5e-35 122.0 33.5 4.4e-34 118.0 35.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EJP67938.1 - 5e-05 22.3 11.0 5e-05 22.3 11.0 2.2 1 1 1 2 2 2 1 MFS_1 like family Holin_BhlA PF10960.8 EJP67938.1 - 0.0057 16.6 0.5 0.02 14.9 0.0 2.1 3 0 0 3 3 3 1 BhlA holin family Amastin PF07344.11 EJP67939.1 - 0.058 13.2 0.0 0.058 13.2 0.0 2.7 1 1 1 2 2 2 0 Amastin surface glycoprotein 7tm_1 PF00001.21 EJP67939.1 - 0.088 12.1 1.5 0.13 11.5 0.5 1.8 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) ECSCR PF15820.5 EJP67939.1 - 0.15 11.9 1.3 0.82 9.5 0.0 2.7 3 1 1 4 4 4 0 Endothelial cell-specific chemotaxis regulator Ribosomal_L7Ae PF01248.26 EJP67941.1 - 8.3e-21 73.5 0.6 8.3e-21 73.5 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EJP67941.1 - 0.0087 16.1 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 CLPTM1 PF05602.12 EJP67941.1 - 0.054 12.5 0.1 0.065 12.2 0.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) ATP_bind_3 PF01171.20 EJP67942.1 - 3.3e-18 66.1 0.0 5.2e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EJP67942.1 - 4.7e-17 61.2 1.2 4.7e-17 61.2 1.2 4.4 5 0 0 5 5 5 1 Zinc-ribbon RecR PF02132.15 EJP67942.1 - 0.0062 16.1 1.1 0.0062 16.1 1.1 3.2 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.16 EJP67942.1 - 0.046 12.5 0.0 0.096 11.5 0.0 1.6 1 0 0 1 1 1 0 tRNA methyl transferase CTU2 PF10288.9 EJP67942.1 - 5.1 7.4 8.6 0.65 10.3 2.5 2.5 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 MWFE PF15879.5 EJP67943.1 - 3.2e-31 107.3 0.4 4.7e-31 106.7 0.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 EJP67944.1 - 8.5e-76 253.6 0.0 1.2e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EJP67944.1 - 1.1e-20 73.0 3.4 2.3e-20 71.9 3.4 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 EJP67944.1 - 6.3e-11 42.2 10.3 3e-10 40.0 10.3 2.3 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EJP67944.1 - 0.00017 21.4 10.4 0.00017 21.4 10.4 2.3 2 0 0 2 2 2 1 PHD-finger zf-4CXXC_R1 PF10497.9 EJP67944.1 - 0.011 16.0 4.1 0.035 14.3 4.1 1.8 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD_2 PF13831.6 EJP67944.1 - 0.038 13.6 2.6 0.1 12.2 2.6 1.8 1 0 0 1 1 1 0 PHD-finger Acetyltransf_7 PF13508.7 EJP67944.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-HC5HC2H PF13771.6 EJP67944.1 - 0.13 12.5 4.1 0.44 10.8 4.1 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-MIZ PF02891.20 EJP67944.1 - 0.21 11.4 4.2 0.45 10.3 4.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF4245 PF14030.6 EJP67944.1 - 0.63 10.0 5.8 2.3 8.2 5.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) zf-RING_9 PF13901.6 EJP67944.1 - 0.71 9.8 7.2 1.2 9.1 7.2 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon SET PF00856.28 EJP67945.1 - 0.054 13.9 0.1 12 6.2 0.0 2.8 2 1 0 2 2 2 0 SET domain Nup96 PF12110.8 EJP67946.1 - 6.8e-92 307.7 0.5 1.1e-91 307.0 0.5 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EJP67946.1 - 1.6e-49 167.8 0.0 2.8e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EJP67946.1 - 1.1e-26 93.5 329.7 8.6e-09 36.1 40.3 11.1 3 2 8 11 11 11 8 Nucleoporin FG repeat region EF-hand_7 PF13499.6 EJP67947.1 - 1.1e-15 57.8 5.1 1.8e-11 44.3 3.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EJP67947.1 - 2e-15 55.1 7.5 4.5e-05 22.7 0.4 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EJP67947.1 - 1.9e-12 46.8 8.9 4.4e-09 36.1 3.6 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EJP67947.1 - 7.6e-12 44.2 4.9 0.00037 20.2 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EJP67947.1 - 2.1e-06 27.0 2.2 0.003 17.0 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EJP67947.1 - 0.0026 18.0 0.5 0.031 14.6 0.2 2.5 3 0 0 3 3 3 1 EF-hand domain ENTH PF01417.20 EJP67948.1 - 2e-49 166.8 0.0 3e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 EJP67948.1 - 0.00025 21.4 42.0 0.00025 21.4 42.0 6.0 2 2 1 3 3 3 1 Domain of unknown function (DUF1720) DUF4264 PF14084.6 EJP67948.1 - 0.0023 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) ANTH PF07651.16 EJP67948.1 - 0.0089 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 EJP67948.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 VHS domain UIM PF02809.20 EJP67948.1 - 0.31 11.1 6.7 0.55 10.3 0.1 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif RCC1 PF00415.18 EJP67949.1 - 2.1e-18 66.6 0.1 0.0002 21.9 0.0 5.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EJP67949.1 - 3e-11 43.5 0.0 4.1e-09 36.6 0.0 2.6 2 0 0 2 2 2 1 BTB/POZ domain RCC1_2 PF13540.6 EJP67949.1 - 9.2e-08 31.7 12.1 2.7e-06 27.0 0.4 4.6 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EJP67949.1 - 3e-07 30.9 0.1 5.3e-06 26.9 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP67949.1 - 0.00066 20.2 0.0 0.0036 17.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP67949.1 - 0.0014 18.9 0.1 0.65 10.7 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Mito_carr PF00153.27 EJP67950.1 - 6.4e-68 224.7 2.4 2.3e-26 91.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EJP67950.1 - 0.27 11.6 1.5 1.5 9.2 1.5 2.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Serine_protease PF18405.1 EJP67950.1 - 0.44 9.7 3.6 8.8 5.4 0.0 3.4 2 1 1 4 4 4 0 Gammaproteobacterial serine protease ATG13 PF10033.9 EJP67952.1 - 5.5e-74 248.9 0.0 8.5e-74 248.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.19 EJP67953.1 - 7.9e-36 123.0 0.1 2e-35 121.7 0.1 1.7 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EJP67953.1 - 1.6e-15 56.4 0.0 3.5e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP67953.1 - 2.1e-14 53.1 1.0 4.3e-14 52.1 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EJP67953.1 - 4.1e-14 52.0 0.0 8.7e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EJP67953.1 - 2.4e-10 40.6 2.5 2.5e-10 40.5 1.0 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EJP67953.1 - 0.0024 17.7 4.0 0.006 16.4 4.0 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif SNF2_N PF00176.23 EJP67954.1 - 4.9e-64 216.2 6.8 1.9e-60 204.4 1.9 3.2 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP67954.1 - 5.1e-17 62.2 0.1 1.5e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP67954.1 - 4.7e-08 33.2 0.2 5e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJP67954.1 - 3.4e-06 26.9 0.1 1.3e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-HIT PF04438.16 EJP67954.1 - 2.4 8.1 4.0 3.2 7.7 1.0 2.3 2 0 0 2 2 2 0 HIT zinc finger NTF2 PF02136.20 EJP67955.1 - 3.3e-28 98.7 0.1 3.7e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 EJP67955.1 - 0.073 13.5 0.0 0.084 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Beta-lactamase PF00144.24 EJP67956.1 - 4.8e-40 137.8 2.7 6.7e-40 137.3 2.7 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EJP67956.1 - 0.00045 20.6 0.0 0.00091 19.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) RE_NgoPII PF09521.10 EJP67957.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 NgoPII restriction endonuclease Seipin PF06775.14 EJP67958.1 - 2.1e-58 197.7 0.7 2.6e-58 197.4 0.7 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF5397 PF17375.2 EJP67958.1 - 0.13 12.0 0.0 4.9 6.9 0.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5397) FCH PF00611.23 EJP67959.1 - 1.6e-15 57.1 0.4 5.1e-15 55.5 0.4 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EJP67959.1 - 6.1e-14 51.4 0.0 1.2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EJP67959.1 - 1.7e-12 46.8 0.0 1.1e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EJP67959.1 - 3.1e-12 46.2 0.1 1.4e-11 44.1 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain Not1 PF04054.15 EJP67960.1 - 1.3e-122 409.3 0.0 2.9e-122 408.2 0.0 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EJP67960.1 - 8e-92 306.7 0.6 1.4e-91 305.9 0.6 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EJP67960.1 - 4.7e-48 162.8 0.5 1.3e-47 161.4 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EJP67960.1 - 5.7e-43 146.3 0.0 1.6e-42 144.8 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EJP67960.1 - 1.2e-36 126.1 1.3 7.4e-36 123.5 0.2 3.0 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat GIT1_C PF12205.8 EJP67960.1 - 0.05 13.7 0.0 0.21 11.7 0.0 2.1 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term PhzC-PhzF PF02567.16 EJP67961.1 - 3.8e-37 128.3 0.1 1.5e-21 77.1 0.0 2.0 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein DEC-1_N PF04625.13 EJP67961.1 - 0.28 10.2 2.9 0.17 10.9 1.4 1.3 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region Methyltransf_23 PF13489.6 EJP67963.1 - 3.9e-16 59.3 0.0 7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP67963.1 - 0.00036 21.2 0.0 0.14 12.9 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP67963.1 - 0.00085 20.0 0.0 0.006 17.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67963.1 - 0.014 16.0 0.0 0.92 10.2 0.0 2.9 1 1 1 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EJP67963.1 - 0.17 11.2 0.0 18 4.6 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EJP67963.1 - 0.18 11.6 0.0 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Pex14_N PF04695.13 EJP67963.1 - 0.86 10.2 5.7 0.3 11.7 0.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3446 PF11928.8 EJP67963.1 - 1.1 9.6 5.0 1.4 9.3 3.6 2.0 1 1 0 1 1 1 0 Early growth response N-terminal domain UPF0029 PF01205.19 EJP67964.1 - 9.6e-26 90.2 0.0 1.8e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Ribosomal_60s PF00428.19 EJP67964.1 - 3.8 8.2 9.3 0.84 10.3 4.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.25 EJP67965.1 - 8.2e-71 238.5 0.0 1.1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP67965.1 - 5e-31 107.9 0.0 6.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJP67965.1 - 0.00038 19.5 0.1 0.02 13.9 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 EJP67965.1 - 0.0013 18.1 0.0 0.0029 17.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EJP67965.1 - 0.0043 17.0 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EJP67965.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EJP67965.1 - 0.073 12.4 0.0 0.15 11.3 0.1 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family LtrA PF06772.11 EJP67966.1 - 9.8e-09 34.9 1.6 9.8e-09 34.9 1.6 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Cyclin_N PF00134.23 EJP67967.1 - 1.3e-14 54.0 0.0 2.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EJP67967.1 - 2.9e-08 34.2 0.3 2.9e-08 34.2 0.3 2.4 2 2 0 2 2 2 1 Cyclin RskA PF10099.9 EJP67967.1 - 0.011 16.0 4.1 0.022 15.1 4.1 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA E1-E2_ATPase PF00122.20 EJP67968.1 - 9.4e-50 168.6 0.8 2.3e-49 167.4 0.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EJP67968.1 - 3.3e-34 119.0 2.2 5.7e-34 118.3 2.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EJP67968.1 - 3.3e-14 53.1 0.1 1.5e-08 34.9 0.0 3.5 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EJP67968.1 - 2.7e-05 24.1 0.1 6.3e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP67968.1 - 0.0028 18.1 0.1 0.0075 16.7 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LytR_C PF13399.6 EJP67968.1 - 0.058 14.4 0.0 1.8 9.6 0.0 2.9 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator DUF3040 PF11239.8 EJP67968.1 - 0.27 11.6 0.0 0.27 11.6 0.0 3.4 4 1 1 5 5 5 0 Protein of unknown function (DUF3040) Peptidase_S10 PF00450.22 EJP67969.1 - 3.7e-73 247.3 0.4 5.5e-73 246.8 0.4 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Methyltransf_23 PF13489.6 EJP67970.1 - 4.1e-19 69.0 0.0 5.6e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP67970.1 - 1.7e-18 67.0 0.0 2.7e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP67970.1 - 3.6e-15 56.4 0.0 7.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP67970.1 - 1.5e-14 54.0 0.0 2.3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP67970.1 - 7.2e-14 52.3 0.0 1.1e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EJP67970.1 - 7.7e-07 28.8 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EJP67970.1 - 0.00037 19.9 0.0 0.0005 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EJP67970.1 - 0.0021 17.4 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EJP67970.1 - 0.0036 16.3 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EJP67970.1 - 0.0046 16.5 0.0 0.0066 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EJP67970.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_PK PF05891.12 EJP67970.1 - 0.058 12.9 0.0 0.23 11.0 0.0 1.7 1 1 1 2 2 2 0 AdoMet dependent proline di-methyltransferase DHBP_synthase PF00926.19 EJP67971.1 - 5.7e-80 267.4 0.0 6.5e-80 267.2 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF5539 PF17693.1 EJP67971.1 - 0.13 11.9 1.2 0.16 11.6 1.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Atx10homo_assoc PF09759.9 EJP67972.1 - 1.6e-12 47.3 0.0 4.4e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain PNP_UDP_1 PF01048.20 EJP67973.1 - 2.7e-40 138.1 0.0 3.2e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4193 PF13834.6 EJP67973.1 - 0.1 13.1 0.0 0.3 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Methyltransf_33 PF10017.9 EJP67974.1 - 1.9e-81 273.6 0.0 2.4e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent adh_short PF00106.25 EJP67974.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans_2 PF11951.8 EJP67975.1 - 5e-19 68.4 0.0 7.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 EJP67977.1 - 5.5e-31 108.4 0.0 6.5e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP67977.1 - 1.7e-09 37.4 0.0 0.00035 19.9 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP67977.1 - 4.4e-07 30.0 0.0 8.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EJP67977.1 - 3.5e-05 23.1 0.5 0.011 14.9 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EJP67977.1 - 0.00012 21.4 0.1 0.00019 20.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EJP67977.1 - 0.00013 22.4 0.0 0.00031 21.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EJP67977.1 - 0.00017 21.5 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EJP67977.1 - 0.00043 19.6 0.0 0.005 16.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP67977.1 - 0.0032 16.2 0.5 0.11 11.1 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 EJP67977.1 - 0.0042 17.1 0.1 4.2 7.3 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding PALP PF00291.25 EJP67977.1 - 0.007 15.8 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UDPG_MGDP_dh_N PF03721.14 EJP67977.1 - 0.029 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 EJP67977.1 - 0.037 12.9 0.0 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 EJP67977.1 - 0.051 13.2 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EJP67977.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 EJP67977.1 - 0.086 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 EJP67977.1 - 0.093 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.24 EJP67977.1 - 0.3 10.1 2.9 0.65 9.0 0.8 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_1 PF00667.20 EJP67978.1 - 5.3e-64 215.8 0.0 1.1e-63 214.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EJP67978.1 - 1.2e-09 38.8 0.0 4.6e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.18 EJP67978.1 - 1.1e-08 35.4 0.0 2.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 EJP67978.1 - 4.8e-07 30.0 0.2 1.2e-06 28.7 0.2 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 EJP67978.1 - 0.00044 20.1 0.6 0.0015 18.4 0.2 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain IFT20 PF14931.6 EJP67978.1 - 0.068 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 zf-Nse PF11789.8 EJP67979.1 - 2.3e-21 75.3 0.1 4.4e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EJP67979.1 - 0.00011 22.1 0.2 0.00022 21.2 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EJP67979.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP67979.1 - 0.074 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EJP67979.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Allexi_40kDa PF05549.11 EJP67979.1 - 0.18 11.3 1.2 0.35 10.4 1.2 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein PAS_9 PF13426.7 EJP67980.1 - 2.8e-13 50.0 0.0 4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EJP67980.1 - 2e-06 27.7 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EJP67980.1 - 0.00031 20.7 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EJP67980.1 - 0.014 15.7 0.0 0.048 13.9 0.0 1.9 1 1 0 1 1 1 0 PAS fold PAS_4 PF08448.10 EJP67980.1 - 0.036 14.3 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold Fapy_DNA_glyco PF01149.24 EJP67981.1 - 8.7e-35 119.8 0.0 1.7e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EJP67981.1 - 1.7e-21 76.0 0.0 2.9e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EJP67981.1 - 0.071 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) LUC7 PF03194.15 EJP67981.1 - 0.26 10.9 2.5 0.51 10.0 2.5 1.4 1 0 0 1 1 1 0 LUC7 N_terminus Apolipoprotein PF01442.18 EJP67982.1 - 0.00026 20.9 0.3 0.00051 20.0 0.3 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PH PF00169.29 EJP67982.1 - 0.0011 19.5 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 PH domain KilA-N PF04383.13 EJP67983.1 - 0.0065 16.3 0.0 0.083 12.8 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Hamartin PF04388.12 EJP67983.1 - 0.035 12.8 18.0 0.046 12.4 18.0 1.1 1 0 0 1 1 1 0 Hamartin protein Tom5 PF10642.9 EJP67983.1 - 0.48 10.5 5.9 0.36 10.9 1.5 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Rho_GDI PF02115.17 EJP67984.1 - 4.1e-65 219.2 0.3 4.5e-65 219.1 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.15 EJP67984.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.6 1 1 0 1 1 1 0 ML domain Ribosomal_S16 PF00886.19 EJP67984.1 - 0.09 12.9 0.1 0.22 11.6 0.1 1.7 1 1 0 1 1 1 0 Ribosomal protein S16 Metallophos PF00149.28 EJP67985.1 - 6.1e-36 124.8 0.3 7.9e-36 124.5 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EJP67985.1 - 0.13 12.7 0.4 0.35 11.3 0.4 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EJP67985.1 - 0.17 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-CCHC PF00098.23 EJP67986.1 - 6.3e-07 29.2 2.1 1.5e-06 28.0 2.1 1.7 1 0 0 1 1 1 1 Zinc knuckle OATP PF03137.20 EJP67987.1 - 0.19 10.0 0.2 0.23 9.7 0.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family LRR_8 PF13855.6 EJP67988.1 - 6.7e-36 121.9 39.9 2.1e-08 33.8 3.2 8.2 4 3 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 EJP67988.1 - 2.5e-34 116.7 41.2 5.4e-07 29.8 1.1 10.0 8 2 2 10 10 10 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EJP67988.1 - 2.8e-08 33.1 21.2 0.3 11.2 0.0 10.4 12 0 0 12 12 12 3 Leucine Rich repeat LRR_1 PF00560.33 EJP67988.1 - 3.9e-05 23.6 28.3 26 5.9 0.0 12.3 13 1 1 14 14 14 1 Leucine Rich Repeat LRR_9 PF14580.6 EJP67988.1 - 7.7e-05 22.3 26.6 0.16 11.4 4.1 5.2 2 2 4 6 6 6 5 Leucine-rich repeat DUF2293 PF10056.9 EJP67990.1 - 2.5e-27 94.9 0.3 2.5e-27 94.9 0.3 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) MRJP PF03022.16 EJP67992.1 - 6.1e-27 94.7 0.0 1.2e-26 93.8 0.0 1.4 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 EJP67992.1 - 1.3e-06 28.2 0.0 0.016 14.8 0.0 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region tRNA-synt_1 PF00133.22 EJP67995.1 - 1.1e-216 720.8 0.0 1.5e-216 720.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EJP67995.1 - 1.9e-22 79.9 0.0 1.8e-21 76.7 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EJP67995.1 - 3.4e-14 52.4 0.0 1.5e-05 24.0 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) FGGY_C PF02782.16 EJP67998.1 - 5.1e-50 170.0 0.2 7.5e-50 169.4 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EJP67998.1 - 3.3e-22 79.3 1.4 5.5e-21 75.3 0.2 2.9 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EJP67998.1 - 0.033 13.7 0.1 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Nic96 PF04097.14 EJP67999.1 - 2e-217 723.6 0.0 2.6e-217 723.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 EJP67999.1 - 1.9e-13 51.1 126.5 5e-08 33.7 51.7 5.2 2 1 2 4 4 4 4 Nucleoporin FG repeat region AAA_33 PF13671.6 EJP68000.1 - 1.5e-14 54.4 0.0 2.4e-14 53.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP68000.1 - 6.4e-10 39.7 0.0 8.1e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EJP68000.1 - 3.4e-08 33.0 0.0 4.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 EJP68000.1 - 1.1e-06 29.1 0.0 1.5e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 EJP68000.1 - 0.0064 16.4 0.0 2.7 7.8 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase KTI12 PF08433.10 EJP68000.1 - 0.0092 15.5 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 EJP68000.1 - 0.017 15.0 0.2 0.12 12.3 0.1 2.0 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 EJP68000.1 - 0.028 14.7 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EJP68000.1 - 0.032 14.6 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EJP68000.1 - 0.037 13.2 0.0 0.086 12.0 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.22 EJP68000.1 - 0.046 13.8 0.1 0.083 13.0 0.1 1.4 1 1 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.6 EJP68000.1 - 0.18 11.5 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EJP68000.1 - 0.19 11.4 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase RFC1 PF08519.12 EJP68001.1 - 8.2e-56 188.5 0.0 8.2e-56 188.5 0.0 2.3 3 0 0 3 3 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EJP68001.1 - 8.3e-14 51.7 0.0 2.3e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EJP68001.1 - 1.9e-08 34.8 0.1 1.6e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EJP68001.1 - 0.0001 22.3 0.0 0.00026 20.9 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 EJP68001.1 - 0.0012 18.7 0.0 0.0043 16.8 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.6 EJP68001.1 - 0.0019 18.7 0.1 0.018 15.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EJP68001.1 - 0.0063 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP68001.1 - 0.0091 16.4 0.7 0.025 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EJP68001.1 - 0.011 16.0 0.0 0.12 12.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EJP68001.1 - 0.038 14.0 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EJP68001.1 - 0.054 13.7 1.4 0.084 13.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 EJP68001.1 - 0.088 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EJP68001.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 EJP68001.1 - 0.21 11.8 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain Ribosomal_L16 PF00252.18 EJP68002.1 - 2.1e-30 105.4 1.2 2.9e-30 105.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 EJP68003.1 - 5.7e-11 42.5 0.0 1.1e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EJP68003.1 - 1.9e-06 28.3 0.1 4e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EJP68003.1 - 3.8e-06 27.2 0.2 7.7e-05 23.0 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP68003.1 - 0.0001 22.7 0.3 0.00081 19.8 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EJP68003.1 - 0.0012 18.6 0.6 0.0043 16.8 0.6 1.9 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.11 EJP68003.1 - 0.0025 18.2 0.0 0.0074 16.7 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain ABC_tran PF00005.27 EJP68003.1 - 0.0061 17.1 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EJP68003.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Resolvase PF00239.21 EJP68003.1 - 0.028 14.5 0.1 1.2 9.2 0.1 2.6 3 0 0 3 3 3 0 Resolvase, N terminal domain T4SS-DNA_transf PF02534.14 EJP68003.1 - 0.06 12.1 0.1 0.17 10.6 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Trypsin PF00089.26 EJP68004.1 - 1.8e-53 181.6 1.7 2e-53 181.4 1.7 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP68004.1 - 8.9e-10 39.6 0.1 1.2e-09 39.3 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain adh_short PF00106.25 EJP68005.1 - 8.7e-36 123.2 2.3 1.1e-35 122.8 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP68005.1 - 4.6e-27 95.1 0.3 5.7e-27 94.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP68005.1 - 1.5e-05 25.0 0.4 2.4e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EJP68005.1 - 5.5e-05 23.1 0.3 0.00011 22.1 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EJP68005.1 - 0.0036 16.8 0.2 0.0066 15.9 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 EJP68005.1 - 0.004 16.8 0.1 0.007 16.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 EJP68005.1 - 0.019 14.5 0.2 0.035 13.7 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family LtrA PF06772.11 EJP68006.1 - 7e-17 61.7 21.0 7e-17 61.7 21.0 2.2 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) RPN6_N PF18055.1 EJP68007.1 - 2.7e-43 147.1 4.4 2.7e-43 147.1 4.4 2.4 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EJP68007.1 - 2.4e-20 73.0 0.4 1e-19 70.9 0.1 2.3 3 1 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EJP68007.1 - 2.5e-10 39.9 0.9 5.6e-10 38.8 0.9 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 EJP68007.1 - 0.0002 21.6 15.3 0.057 13.7 1.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat DDRGK PF09756.9 EJP68007.1 - 0.00031 20.4 0.2 0.00031 20.4 0.2 2.1 2 0 0 2 2 2 1 DDRGK domain TPR_MalT PF17874.1 EJP68007.1 - 0.00083 18.8 3.8 0.00083 18.8 3.8 2.2 2 2 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 EJP68007.1 - 0.02 14.9 3.0 2.8 8.2 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DprA_WH PF17782.1 EJP68007.1 - 0.04 14.0 0.0 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 DprA winged helix domain HTH_Crp_2 PF13545.6 EJP68007.1 - 0.048 13.6 0.1 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF4456 PF14644.6 EJP68007.1 - 0.1 12.2 4.7 0.93 9.1 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) TPR_10 PF13374.6 EJP68007.1 - 0.41 10.6 4.6 18 5.4 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EJP68007.1 - 0.58 10.7 11.0 5.7 7.5 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF87 PF01935.17 EJP68007.1 - 0.8 9.7 4.9 1 9.4 0.1 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain GrpE PF01025.19 EJP68008.1 - 6.9e-49 165.7 9.7 8.8e-49 165.4 9.7 1.1 1 0 0 1 1 1 1 GrpE SCHIP-1 PF10148.9 EJP68008.1 - 0.00074 19.2 2.3 0.0012 18.6 2.3 1.2 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 SopD PF11047.8 EJP68008.1 - 0.042 13.0 0.7 0.042 13.0 0.7 1.4 2 0 0 2 2 2 0 Salmonella outer protein D Yos1 PF08571.10 EJP68009.1 - 4.4e-18 65.3 0.0 4.8e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Yos1-like Bystin PF05291.11 EJP68011.1 - 5.2e-131 436.2 0.0 6.6e-131 435.9 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.14 EJP68012.1 - 1.3e-64 217.4 0.1 3.8e-64 215.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EJP68012.1 - 7.2e-24 83.4 0.7 1.6e-23 82.3 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) V-ATPase_H_N PF03224.14 EJP68012.1 - 0.03 13.6 0.0 0.058 12.7 0.0 1.5 1 1 0 1 1 1 0 V-ATPase subunit H BESS PF02944.20 EJP68012.1 - 0.055 13.3 2.2 0.13 12.1 2.2 1.7 1 0 0 1 1 1 0 BESS motif Kelch_5 PF13854.6 EJP68013.1 - 6.2e-13 48.4 3.9 2.9e-12 46.3 0.7 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 EJP68013.1 - 4.1e-07 30.1 1.9 1.4e-05 25.2 0.1 4.3 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_4 PF13418.6 EJP68013.1 - 1.5e-05 24.9 4.0 0.18 11.9 0.5 4.8 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EJP68013.1 - 0.00034 20.2 8.0 0.092 12.3 0.1 4.1 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EJP68013.1 - 0.0015 18.7 2.9 0.31 11.4 0.2 4.0 3 1 0 3 3 3 1 Kelch motif stn_TNFRSF12A PF12191.8 EJP68013.1 - 0.096 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Peptidase_M24 PF00557.24 EJP68014.1 - 3.1e-41 141.4 0.1 5.8e-41 140.5 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 SPT6_acidic PF14632.6 EJP68014.1 - 0.11 13.1 2.1 0.22 12.1 2.1 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PGA2 PF07543.12 EJP68014.1 - 0.12 12.4 2.2 0.24 11.4 2.2 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Drc1-Sld2 PF11719.8 EJP68014.1 - 0.9 9.0 16.7 0.75 9.3 0.2 2.5 2 0 0 2 2 2 0 DNA replication and checkpoint protein BIR PF00653.21 EJP68015.1 - 9.7e-46 154.3 6.1 1.5e-22 80.0 2.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain CoA_binding_2 PF13380.6 EJP68016.1 - 1.4e-24 86.8 0.1 1.8e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.12 EJP68017.1 - 5.1e-22 78.3 0.0 7.7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP68017.1 - 6.3e-19 68.5 0.0 1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP68017.1 - 1.5e-10 41.7 0.0 2.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP68017.1 - 4.5e-10 39.5 0.0 5.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP68017.1 - 1.4e-08 34.8 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP68017.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EJP68017.1 - 3.7e-06 26.6 0.0 6.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EJP68017.1 - 1.3e-05 24.5 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase tRNA_U5-meth_tr PF05958.11 EJP68017.1 - 0.00041 19.4 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase CMAS PF02353.20 EJP68017.1 - 0.009 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EJP68017.1 - 0.0093 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EJP68017.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.12 EJP68017.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 EJP68017.1 - 0.038 13.4 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) EF-hand_7 PF13499.6 EJP68018.1 - 4.4e-12 46.3 0.2 8.4e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EJP68018.1 - 4.8e-12 46.0 0.0 1.3e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EJP68018.1 - 3.3e-10 39.0 0.8 0.0014 18.4 0.0 3.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EJP68018.1 - 1.5e-09 36.7 0.7 0.005 16.3 0.0 3.8 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EJP68018.1 - 7.2e-07 29.0 0.3 5.9e-05 22.8 0.1 3.1 3 1 1 4 4 4 1 EF-hand domain pair Peptidase_M3 PF01432.20 EJP68019.1 - 3.2e-135 452.0 0.0 3.9e-135 451.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 EJP68019.1 - 0.073 11.7 0.0 0.42 9.2 0.0 1.9 2 0 0 2 2 2 0 Angiotensin-converting enzyme MFS_1 PF07690.16 EJP68020.1 - 2.5e-34 118.8 22.5 2.5e-34 118.8 22.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily YtpI PF14007.6 EJP68021.1 - 0.14 12.3 0.8 2.7 8.2 0.1 2.4 2 0 0 2 2 2 0 YtpI-like protein Git3 PF11710.8 EJP68021.1 - 0.31 10.8 10.4 0.57 9.9 10.4 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Sugar_tr PF00083.24 EJP68022.1 - 2.1e-06 26.9 8.5 4e-06 26.0 8.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP68022.1 - 6.1e-06 25.4 33.1 6.1e-06 25.4 33.1 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily Sulfate_transp PF00916.20 EJP68023.1 - 8e-96 321.1 20.8 1.1e-95 320.6 20.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EJP68023.1 - 6.8e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain F-box-like PF12937.7 EJP68023.1 - 0.0033 17.3 0.3 0.0083 16.0 0.3 1.7 1 0 0 1 1 1 1 F-box-like MFS_MOT1 PF16983.5 EJP68023.1 - 0.21 12.0 19.6 0.017 15.5 6.6 3.3 2 2 0 2 2 2 0 Molybdate transporter of MFS superfamily Abhydrolase_3 PF07859.13 EJP68024.1 - 3.5e-20 72.8 0.0 7.5e-20 71.7 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP68024.1 - 7.4e-14 51.4 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF5316 PF17247.2 EJP68024.1 - 0.031 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5316) RskA PF10099.9 EJP68024.1 - 0.051 13.9 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA GMC_oxred_N PF00732.19 EJP68025.1 - 4.8e-73 246.1 0.0 6e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP68025.1 - 3.1e-38 131.5 0.0 4.8e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EJP68025.1 - 0.00022 21.4 0.3 0.00073 19.7 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP68025.1 - 0.00047 19.4 0.3 0.037 13.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EJP68025.1 - 0.00081 18.5 0.3 0.0012 17.9 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EJP68025.1 - 0.0016 17.7 0.0 0.006 15.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP68025.1 - 0.0021 17.7 0.5 0.0045 16.6 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EJP68025.1 - 0.12 11.6 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Glyco_transf_22 PF03901.17 EJP68027.1 - 1.3e-83 281.5 20.1 1.6e-83 281.3 20.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MORN PF02493.20 EJP68027.1 - 0.97 9.5 4.2 1.2 9.1 0.6 2.6 2 0 0 2 2 2 0 MORN repeat Gar1 PF04410.14 EJP68028.1 - 2.7e-43 147.4 1.9 3.4e-43 147.1 0.0 2.0 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region Cwf_Cwc_15 PF04889.12 EJP68028.1 - 0.01 15.6 16.2 0.017 14.9 6.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3807 PF12720.7 EJP68028.1 - 3.2 8.0 16.3 3.5 7.9 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SR-25 PF10500.9 EJP68028.1 - 8.6 5.9 16.3 6.8 6.2 3.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_M28 PF04389.17 EJP68029.1 - 7e-27 94.4 0.0 1.3e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EJP68029.1 - 5.2e-06 26.3 0.2 1.3e-05 25.0 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_S19e PF01090.19 EJP68029.1 - 0.028 14.1 0.4 0.57 9.9 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S19e TBPIP PF07106.13 EJP68029.1 - 0.12 12.3 0.5 0.27 11.2 0.5 1.6 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain EF-hand_6 PF13405.6 EJP68029.1 - 1.2 9.2 3.4 56 4.1 0.7 3.3 3 0 0 3 3 3 0 EF-hand domain Cupin_2 PF07883.11 EJP68030.1 - 3.5e-10 39.5 0.0 5.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EJP68030.1 - 0.0025 17.5 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 EJP68030.1 - 0.0053 16.6 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.6 EJP68030.1 - 0.023 13.8 0.0 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) DMSP_lyase PF16867.5 EJP68030.1 - 0.035 13.8 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase ADH_zinc_N_2 PF13602.6 EJP68031.1 - 2.7e-24 86.7 0.1 5.4e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EJP68031.1 - 3e-16 59.6 0.3 4.6e-16 59.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CFEM PF05730.11 EJP68032.1 - 4.3e-11 42.7 12.3 6.4e-11 42.2 12.3 1.3 1 0 0 1 1 1 1 CFEM domain Hexapep PF00132.24 EJP68032.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) HlyD_2 PF12700.7 EJP68033.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DSPc PF00782.20 EJP68034.1 - 2.8e-05 23.9 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EJP68034.1 - 0.00038 20.6 0.0 0.001 19.2 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF442 PF04273.13 EJP68034.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative phosphatase (DUF442) EccE PF11203.8 EJP68034.1 - 0.0042 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative type VII ESX secretion system translocon, EccE Y_phosphatase3 PF13350.6 EJP68034.1 - 0.02 14.8 0.1 0.073 13.0 0.1 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family DctP PF03480.13 EJP68034.1 - 0.029 13.7 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Y_phosphatase PF00102.27 EJP68034.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Sld5 PF05916.11 EJP68035.1 - 2.2e-29 102.1 0.0 3.3e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Sugar_tr PF00083.24 EJP68036.1 - 8.1e-99 331.5 18.7 9.2e-99 331.3 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP68036.1 - 6.4e-22 77.9 25.2 6.4e-22 77.9 25.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EJP68036.1 - 0.0021 16.7 3.0 0.0021 16.7 3.0 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein COesterase PF00135.28 EJP68037.1 - 7.8e-55 186.7 0.0 2e-54 185.4 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EJP68037.1 - 9.9e-06 25.6 0.2 0.0019 18.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold HTH_1 PF00126.27 EJP68037.1 - 0.021 14.7 0.1 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Archease PF01951.16 EJP68037.1 - 0.14 12.4 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) DJ-1_PfpI PF01965.24 EJP68038.1 - 3.8e-17 62.6 0.0 5.1e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.18 EJP68039.1 - 1.2e-15 57.3 0.4 2e-15 56.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain M20_dimer PF07687.14 EJP68040.1 - 7.4e-20 70.9 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EJP68040.1 - 1.7e-16 60.6 2.0 1.8e-15 57.2 2.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EJP68040.1 - 0.00061 19.5 0.1 0.00061 19.5 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 Acetyltransf_9 PF13527.7 EJP68041.1 - 0.002 18.2 0.1 0.0044 17.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP68041.1 - 0.015 15.7 0.0 0.058 13.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ProRS-C_1 PF09180.11 EJP68042.1 - 3.7e-24 84.7 0.6 6.1e-24 84.0 0.1 1.7 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EJP68042.1 - 1.3e-19 70.8 0.0 2.4e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EJP68042.1 - 2e-18 66.3 0.0 5e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Peptidase_S49_N PF08496.10 EJP68042.1 - 2.1 8.4 4.5 48 4.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cpn60_TCP1 PF00118.24 EJP68043.1 - 1.2e-152 509.0 11.5 1.4e-152 508.8 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UCR_TM PF02921.14 EJP68044.1 - 2.7e-10 40.6 0.7 9.3e-10 38.9 0.7 2.0 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EJP68044.1 - 3.5e-09 36.5 0.3 5.7e-09 35.8 0.3 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Glyco_hydro_18 PF00704.28 EJP68045.1 - 4.4e-62 210.6 1.1 2.8e-61 207.9 0.6 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.6 EJP68045.1 - 7.4e-05 23.1 0.4 0.00041 20.7 0.4 2.3 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF3328 PF11807.8 EJP68048.1 - 1.5e-34 119.7 0.8 2e-34 119.3 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) LysM PF01476.20 EJP68049.1 - 4.4e-22 77.9 8.3 6.5e-07 29.3 0.2 5.5 5 0 0 5 5 5 5 LysM domain DUF1153 PF06627.11 EJP68049.1 - 0.025 14.7 0.0 4.2 7.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1153) UPF0203 PF05254.12 EJP68049.1 - 0.22 11.8 15.2 4 7.8 0.4 4.9 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0203) BrkDBD PF09607.10 EJP68049.1 - 0.29 10.9 5.8 0.42 10.4 0.1 3.0 4 0 0 4 4 4 0 Brinker DNA-binding domain MMS1_N PF10433.9 EJP68050.1 - 3e-108 362.6 0.0 5e-108 361.8 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EJP68050.1 - 8.9e-61 206.0 0.0 5.1e-60 203.5 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EJP68050.1 - 0.16 12.3 0.0 3.3 8.1 0.0 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EJP68050.1 - 0.16 12.5 0.7 11 6.6 0.0 4.1 5 0 0 5 5 5 0 PQQ-like domain R3H-assoc PF13902.6 EJP68052.1 - 1.4e-24 86.9 0.8 1.4e-24 86.9 0.8 1.8 2 0 0 2 2 2 1 R3H-associated N-terminal domain Adeno_terminal PF02459.15 EJP68052.1 - 4.2 5.6 4.9 6 5.1 4.9 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PQ-loop PF04193.14 EJP68053.1 - 1.6e-22 79.1 3.4 3.7e-12 45.8 0.2 3.5 4 1 1 5 5 5 2 PQ loop repeat TetR_C_33 PF13305.6 EJP68053.1 - 0.11 13.3 0.9 0.25 12.1 0.6 2.0 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CrgA PF06781.12 EJP68053.1 - 1.4 9.1 8.4 2.6 8.2 0.7 3.7 3 1 1 4 4 4 0 Cell division protein CrgA DUF2838 PF10998.8 EJP68053.1 - 5.3 7.3 8.0 0.47 10.7 2.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2838) SKG6 PF08693.10 EJP68055.1 - 0.006 16.0 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 EJP68055.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor RTA1 PF04479.13 EJP68056.1 - 4.5e-37 127.7 2.6 1.5e-35 122.7 1.9 2.1 2 0 0 2 2 2 1 RTA1 like protein CoA_binding_3 PF13727.6 EJP68056.1 - 0.049 13.6 2.2 0.77 9.7 1.6 2.2 2 0 0 2 2 2 0 CoA-binding domain DUF3339 PF11820.8 EJP68056.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3339) DUF5134 PF17197.4 EJP68056.1 - 0.3 11.0 6.3 0.51 10.2 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) Yip1 PF04893.17 EJP68056.1 - 1.9 8.2 9.1 0.57 9.9 5.7 1.9 2 0 0 2 2 2 0 Yip1 domain Ion_trans PF00520.31 EJP68057.1 - 6.7e-06 25.5 27.1 8.7e-05 21.9 27.1 2.2 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EJP68057.1 - 0.012 14.3 15.1 10 4.7 15.0 2.2 1 1 0 1 1 1 0 Polycystin cation channel PNTB_4TM PF12769.7 EJP68057.1 - 0.65 10.5 3.5 0.44 11.0 0.2 2.4 2 1 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch SH3_1 PF00018.28 EJP68059.1 - 4.7e-27 93.4 0.0 2.5e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EJP68059.1 - 2.2e-18 65.8 0.0 1.1e-09 37.9 0.1 2.9 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EJP68059.1 - 1.5e-13 50.7 0.0 2.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EJP68059.1 - 1.3e-11 43.9 0.0 4.1e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain MG2 PF01835.19 EJP68059.1 - 0.089 13.3 0.1 0.22 12.0 0.1 1.7 1 0 0 1 1 1 0 MG2 domain SAC3_GANP PF03399.16 EJP68060.1 - 5e-25 88.5 0.6 5e-23 81.9 0.6 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EJP68060.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family EAP30 PF04157.16 EJP68061.1 - 1.2e-41 142.5 0.1 1.5e-41 142.3 0.1 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family HTH_ABP1_N PF18107.1 EJP68062.1 - 2.2e-25 88.1 2.2 5.3e-25 86.9 2.2 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 EJP68062.1 - 3.4e-17 62.2 0.3 2.3e-16 59.5 0.2 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain ATP19 PF11022.8 EJP68063.1 - 1.3e-28 99.1 0.1 1.4e-28 99.0 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K MTP18 PF10558.9 EJP68064.1 - 2.2e-81 271.9 0.5 2.7e-81 271.6 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.16 EJP68065.1 - 3.1e-25 88.1 25.4 1.1e-12 47.9 10.8 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EJP68065.1 - 0.0098 16.1 4.5 0.0098 16.1 4.5 2.7 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EJP68065.1 - 0.017 15.5 14.5 0.23 11.9 5.4 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 EJP68065.1 - 4.3 7.6 18.6 3.2 8.0 1.4 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain Peptidase_C39 PF03412.15 EJP68066.1 - 0.0095 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 EJP68066.1 - 0.011 15.7 0.0 0.048 13.6 0.0 2.0 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 BtrH_N PF14399.6 EJP68066.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Butirosin biosynthesis protein H, N-terminal Peptidase_C39_2 PF13529.6 EJP68066.1 - 0.052 14.1 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase_C39 like family Rad4 PF03835.15 EJP68067.1 - 4.1e-29 101.2 1.4 1.5e-28 99.4 1.4 2.0 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EJP68067.1 - 2.5e-28 98.3 2.3 3.7e-28 97.7 1.0 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EJP68067.1 - 2.2e-16 59.4 0.2 5e-16 58.3 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EJP68067.1 - 1.7e-13 51.3 0.5 1.7e-13 51.3 0.5 4.4 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Dcc1 PF09724.9 EJP68068.1 - 1.2e-09 37.9 0.0 1.4e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 ORC4_C PF14629.6 EJP68069.1 - 3.5e-66 222.7 0.0 5.5e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EJP68069.1 - 5.1e-14 53.0 0.1 1.2e-13 51.8 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.6 EJP68069.1 - 1.5e-12 46.8 1.4 2.7e-12 46.0 1.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EJP68069.1 - 1e-11 44.5 6.4 1.7e-11 43.8 6.4 1.3 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.6 EJP68069.1 - 9.8e-09 35.6 0.0 2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EJP68069.1 - 1.5e-07 31.9 0.0 3.9e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EJP68069.1 - 9.2e-06 25.7 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EJP68069.1 - 4.3e-05 23.3 0.0 8.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP68069.1 - 0.0002 21.7 0.0 0.00041 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EJP68069.1 - 0.00032 20.4 0.1 0.001 18.8 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain FYVE_2 PF02318.16 EJP68069.1 - 0.0029 17.8 0.5 0.0058 16.8 0.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger AAA_7 PF12775.7 EJP68069.1 - 0.0039 16.7 0.0 0.0073 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 EJP68069.1 - 0.0083 16.1 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EJP68069.1 - 0.0085 16.1 0.0 0.02 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EJP68069.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EJP68069.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EJP68069.1 - 0.018 14.4 0.1 0.44 9.9 0.1 2.2 1 1 0 1 1 1 0 Bacterial TniB protein TIP49 PF06068.13 EJP68069.1 - 0.024 13.9 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain C1_1 PF00130.22 EJP68069.1 - 0.027 14.4 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EJP68069.1 - 0.03 14.6 1.3 0.03 14.6 1.3 2.0 2 0 0 2 2 2 0 C1 domain ABC_tran PF00005.27 EJP68069.1 - 0.035 14.6 0.0 0.064 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 EJP68069.1 - 0.035 13.3 0.0 0.089 12.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.22 EJP68069.1 - 0.037 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 EJP68069.1 - 0.061 13.5 0.0 0.24 11.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EJP68069.1 - 0.073 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EJP68069.1 - 0.092 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prok-RING_1 PF14446.6 EJP68069.1 - 0.093 12.7 3.8 0.21 11.5 3.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AAA_25 PF13481.6 EJP68069.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EJP68069.1 - 0.21 10.6 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DNA_RNApol_7kD PF03604.13 EJP68069.1 - 1 9.1 5.2 0.17 11.6 1.1 1.8 2 0 0 2 2 1 0 DNA directed RNA polymerase, 7 kDa subunit RGS PF00615.19 EJP68072.1 - 5.5e-36 123.4 0.4 2.3e-35 121.4 0.1 2.3 4 0 0 4 4 4 1 Regulator of G protein signaling domain DEP PF00610.21 EJP68072.1 - 7e-24 83.7 0.0 1.7e-20 72.9 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mrr_N PF14338.6 EJP68072.1 - 0.068 13.3 0.0 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Mrr N-terminal domain CDC73_C PF05179.14 EJP68075.1 - 4.7e-55 185.6 0.0 6.8e-55 185.0 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Mito_carr PF00153.27 EJP68076.1 - 1.6e-62 207.4 1.1 5.6e-22 77.5 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJP68076.1 - 0.1 11.7 0.0 1.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Gammaproteobacterial serine protease MT-A70 PF05063.14 EJP68077.1 - 5.1e-32 111.2 0.0 6.8e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Pheromone PF08015.11 EJP68077.1 - 8.4 7.5 8.5 15 6.7 3.3 3.0 2 1 1 3 3 3 0 Fungal mating-type pheromone Ribosomal_L23 PF00276.20 EJP68078.1 - 1.2e-09 38.4 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Transferase PF02458.15 EJP68079.1 - 9e-08 31.2 0.0 1.9e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Transferase family Cwf_Cwc_15 PF04889.12 EJP68081.1 - 3.9 7.1 12.6 0.028 14.2 4.2 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Spt5_N PF11942.8 EJP68081.1 - 8.1 7.5 12.2 0.7 10.9 6.5 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Mito_carr PF00153.27 EJP68082.1 - 6.8e-64 211.8 0.2 1.8e-21 75.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.23 EJP68083.1 - 3.9e-07 29.9 0.0 1.1e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like EIF_2_alpha PF07541.12 EJP68084.1 - 8.4e-38 129.0 0.0 1.7e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EJP68084.1 - 2.5e-13 50.2 1.1 6.3e-13 48.9 1.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain WD40 PF00400.32 EJP68085.1 - 1e-10 42.0 0.7 0.048 14.5 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP68085.1 - 0.00016 21.9 0.0 0.22 11.8 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 EJP68086.1 - 1.7e-64 217.9 0.0 2e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DMRT-like PF15791.5 EJP68087.1 - 0.25 11.7 2.4 0.31 11.5 0.4 2.1 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 SE PF08491.10 EJP68088.1 - 6.7e-87 291.0 0.0 9.3e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EJP68088.1 - 1.9e-11 43.8 0.3 1.2e-10 41.2 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJP68088.1 - 7.5e-10 38.9 0.4 8.4e-08 32.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EJP68088.1 - 3.2e-07 29.8 0.9 3.5e-06 26.4 0.9 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EJP68088.1 - 3e-06 27.4 0.3 6.1e-06 26.4 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJP68088.1 - 7.9e-06 25.2 0.3 1.5e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EJP68088.1 - 2e-05 24.1 2.8 4.2e-05 23.1 2.8 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EJP68088.1 - 0.00014 21.2 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EJP68088.1 - 0.00056 19.2 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP68088.1 - 0.0025 18.3 0.3 0.0091 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP68088.1 - 0.0088 14.8 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 EJP68088.1 - 0.011 15.3 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 EJP68088.1 - 0.02 14.0 0.8 0.32 10.0 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EJP68088.1 - 0.05 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EJP68088.1 - 0.052 13.5 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 EJP68088.1 - 0.056 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EJP68088.1 - 0.094 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EJP68088.1 - 0.16 11.3 0.1 0.94 8.8 0.1 2.0 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.14 EJP68088.1 - 0.18 10.6 0.9 3.6 6.3 0.1 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Glycos_transf_2 PF00535.26 EJP68089.1 - 2.2e-22 79.6 0.0 4.2e-22 78.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EJP68089.1 - 1.4e-09 38.2 0.2 6.1e-07 29.6 0.1 2.3 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EJP68089.1 - 0.031 13.8 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF3533 PF12051.8 EJP68090.1 - 0.39 9.6 6.3 0.59 9.0 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) SMK-1 PF04802.15 EJP68091.1 - 1.1e-81 273.2 0.1 1.1e-81 273.2 0.1 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Telomere_reg-2 PF10193.9 EJP68091.1 - 0.1 13.0 0.2 4.1 7.9 0.0 3.2 2 1 1 3 3 3 0 Telomere length regulation protein AAA PF00004.29 EJP68092.1 - 8.3e-50 168.6 0.0 9.2e-40 136.1 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP68092.1 - 5.8e-15 54.8 5.2 2.4e-11 43.2 1.9 3.0 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EJP68092.1 - 1.7e-10 41.5 0.4 0.18 12.2 0.0 5.2 3 2 2 6 6 6 3 AAA ATPase domain AAA_22 PF13401.6 EJP68092.1 - 0.0001 22.6 0.4 1.9 8.8 0.1 4.0 3 1 1 4 4 4 1 AAA domain AAA_5 PF07728.14 EJP68092.1 - 0.00016 21.7 0.6 0.045 13.7 0.0 4.0 3 2 1 4 4 4 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EJP68092.1 - 0.00022 21.2 0.0 0.69 10.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EJP68092.1 - 0.00024 21.4 0.1 0.075 13.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EJP68092.1 - 0.00068 19.4 0.0 0.016 15.0 0.0 3.1 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 EJP68092.1 - 0.0038 17.2 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 EJP68092.1 - 0.0068 16.0 0.2 2.1 7.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EJP68092.1 - 0.0089 16.2 0.0 0.13 12.3 0.0 2.8 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EJP68092.1 - 0.0097 15.3 0.3 0.35 10.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EJP68092.1 - 0.012 15.5 0.7 1.4 8.8 0.2 3.0 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 EJP68092.1 - 0.014 15.5 0.3 6.3 6.9 0.0 3.3 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 EJP68092.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 EJP68092.1 - 0.02 15.3 0.0 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase MTCP1 PF08991.10 EJP68093.1 - 0.00024 21.3 3.0 0.00036 20.7 3.0 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EJP68093.1 - 0.00069 19.7 5.9 0.0011 19.1 5.9 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EJP68093.1 - 0.013 15.9 2.2 0.32 11.4 2.2 2.1 1 1 0 1 1 1 0 GCK domain Hydrophobin_2 PF06766.11 EJP68093.1 - 0.04 13.9 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 Fungal hydrophobin COX17 PF05051.13 EJP68093.1 - 0.07 13.5 1.8 0.12 12.8 1.8 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 EJP68093.1 - 0.21 11.9 5.0 0.32 11.3 4.5 1.5 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Prenyltrans PF00432.21 EJP68094.1 - 5.2e-33 112.5 10.0 2.2e-08 33.7 0.1 6.5 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EJP68094.1 - 0.00084 18.5 0.8 0.41 9.7 0.0 3.0 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain adh_short PF00106.25 EJP68095.1 - 6e-23 81.3 0.0 6.5e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EJP68095.1 - 9.3e-14 51.5 0.0 1.3e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP68095.1 - 6.9e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP68095.1 - 0.0002 20.9 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP68095.1 - 0.00036 20.0 0.0 0.00071 19.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase WES_acyltransf PF03007.16 EJP68095.1 - 0.012 15.4 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Prp19 PF08606.11 EJP68095.1 - 0.016 15.2 0.3 0.027 14.5 0.3 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like THF_DHG_CYH_C PF02882.19 EJP68095.1 - 0.036 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 EJP68095.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MutS_V PF00488.21 EJP68096.1 - 9.3e-61 205.1 0.1 1.7e-60 204.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EJP68096.1 - 2.1e-28 99.9 3.9 9.1e-28 97.8 2.2 2.5 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EJP68096.1 - 6.4e-09 36.1 0.0 1.6e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EJP68096.1 - 0.0017 18.7 0.1 0.013 15.8 0.0 2.6 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 EJP68096.1 - 0.019 14.6 0.1 0.083 12.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain WD40 PF00400.32 EJP68097.1 - 2.3e-53 177.0 34.2 1.7e-11 44.4 0.2 9.1 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP68097.1 - 3.3e-19 69.0 6.8 0.00043 20.5 0.1 6.5 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP68097.1 - 2.4e-06 26.8 0.2 2.4 7.1 0.0 4.9 3 3 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EJP68097.1 - 5.5e-06 26.4 1.3 0.0029 17.5 0.0 3.2 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A FAR1 PF03101.15 EJP68097.1 - 7.6e-06 26.5 0.7 2.6e-05 24.8 0.7 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain PD40 PF07676.12 EJP68097.1 - 7.8e-05 22.5 0.7 0.87 9.6 0.0 3.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat NLE PF08154.12 EJP68097.1 - 0.0021 18.5 0.1 0.0052 17.3 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EJP68097.1 - 0.0066 15.1 5.6 0.48 9.0 0.1 3.7 3 1 0 4 4 4 2 Nucleoporin Nup120/160 DmpG_comm PF07836.11 EJP68097.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 DmpG-like communication domain WD40_like PF17005.5 EJP68097.1 - 0.021 14.1 0.0 14 4.9 0.0 3.5 4 0 0 4 4 4 0 WD40-like domain Proteasome_A_N PF10584.9 EJP68097.1 - 0.043 13.5 0.4 9.8 6.0 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DBD_Tnp_Mut PF03108.15 EJP68097.1 - 0.064 13.3 0.3 0.22 11.5 0.3 1.9 1 0 0 1 1 1 0 MuDR family transposase AFT PF08731.11 EJP68097.1 - 0.17 12.3 1.2 0.64 10.4 0.1 2.5 3 0 0 3 3 3 0 Transcription factor AFT Glyco_transf_20 PF00982.21 EJP68098.1 - 3.9e-166 553.4 0.1 5e-166 553.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EJP68098.1 - 1.3e-40 139.0 0.0 2.3e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EJP68098.1 - 0.0062 16.3 0.0 0.17 11.6 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4873 PF16170.5 EJP68098.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4873) Glyco_transf_5 PF08323.11 EJP68098.1 - 0.11 12.2 0.4 0.2 11.3 0.4 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Aminotran_4 PF01063.19 EJP68099.1 - 7.4e-19 68.5 0.0 9.2e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HsbA PF12296.8 EJP68100.1 - 5.6e-28 97.8 3.5 7.1e-28 97.4 3.5 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A GM_CSF PF01109.17 EJP68101.1 - 0.11 12.7 0.2 1.7 8.8 0.1 2.0 1 1 1 2 2 2 0 Granulocyte-macrophage colony-stimulating factor GMP_synt_C PF00958.22 EJP68102.1 - 3.1e-38 129.7 0.0 5.6e-38 128.9 0.0 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EJP68102.1 - 2.9e-35 121.8 0.0 6.1e-35 120.7 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EJP68102.1 - 5.4e-09 35.5 0.1 1.2e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EJP68102.1 - 2.8e-06 27.2 0.0 8.8e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EJP68102.1 - 0.00056 18.8 0.0 0.0028 16.5 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 EJP68102.1 - 0.0012 18.5 0.0 0.0033 17.0 0.1 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EJP68102.1 - 0.0068 15.9 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 EJP68102.1 - 0.0087 15.4 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 EJP68102.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2501 PF10696.9 EJP68102.1 - 0.039 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) ATP_bind_3 PF01171.20 EJP68102.1 - 0.18 11.5 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 PP-loop family Hydrophobin_2 PF06766.11 EJP68103.1 - 2.9e-25 88.0 3.3 3.5e-25 87.7 3.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Isochorismatase PF00857.20 EJP68104.1 - 8.6e-15 55.3 0.1 2.2e-14 54.0 0.1 1.6 1 1 0 1 1 1 1 Isochorismatase family SBP_bac_11 PF13531.6 EJP68105.1 - 0.013 15.2 1.9 0.016 14.9 0.1 1.9 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein p450 PF00067.22 EJP68106.1 - 3.2e-66 224.0 0.0 4.1e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EJP68107.1 - 3.5e-05 23.3 0.0 8.8e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 EJP68107.1 - 0.25 10.6 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3328 PF11807.8 EJP68108.1 - 1.1e-50 172.4 3.3 1.4e-50 172.1 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Adipokin_hormo PF06377.11 EJP68109.1 - 7.3e-05 23.0 19.3 3.9 7.9 0.1 5.2 4 1 1 5 5 5 5 Adipokinetic hormone DUF3328 PF11807.8 EJP68110.1 - 8.9e-41 140.1 0.9 9.9e-41 139.9 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EJP68111.1 - 0.0019 18.0 0.2 0.0028 17.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Omega-toxin PF06357.11 EJP68112.1 - 0.68 9.8 3.4 69 3.3 0.1 3.3 3 0 0 3 3 3 0 Omega-atracotoxin CTP_transf_like PF01467.26 EJP68113.1 - 2e-18 67.0 0.0 2.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Pex14_N PF04695.13 EJP68113.1 - 2.2 8.9 11.3 3.7 8.2 11.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Imm70 PF15601.6 EJP68114.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 70 PI-PLC-X PF00388.19 EJP68115.1 - 4.7e-46 156.0 0.0 8.9e-46 155.1 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EJP68115.1 - 2.5e-36 124.5 0.0 4.8e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain YL1 PF05764.13 EJP68115.1 - 0.0081 16.3 3.7 0.013 15.7 3.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein C2 PF00168.30 EJP68115.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 C2 domain TFIIF_alpha PF05793.12 EJP68115.1 - 2.1 6.8 7.9 3 6.3 7.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GFO_IDH_MocA PF01408.22 EJP68116.1 - 2.9e-25 89.4 0.1 4.8e-25 88.7 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EJP68116.1 - 4.5e-05 23.4 0.0 9.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DSRB PF10781.9 EJP68116.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Dextransucrase DSRB NAD_binding_2 PF03446.15 EJP68116.1 - 0.025 14.7 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.24 EJP68117.1 - 4.6e-112 375.2 24.7 1.1e-111 373.9 24.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP68117.1 - 1.4e-27 96.6 43.9 1.2e-19 70.5 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP68117.1 - 0.0028 16.1 5.9 0.0028 16.1 5.9 2.4 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF928 PF06051.12 EJP68117.1 - 0.056 13.3 0.1 0.088 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) DUF2205 PF10224.9 EJP68118.1 - 5.7e-37 125.6 1.0 7.5e-37 125.2 1.0 1.2 1 0 0 1 1 1 1 Short coiled-coil protein TACC_C PF05010.14 EJP68118.1 - 0.012 15.4 0.2 0.016 15.0 0.2 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_32 PF13654.6 EJP68118.1 - 0.018 13.9 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain Hydrophobin PF01185.18 EJP68119.1 - 3e-11 43.8 5.2 3.9e-11 43.4 5.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Peptidase_M20 PF01546.28 EJP68120.1 - 2e-18 66.8 3.0 2.1e-17 63.5 3.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJP68120.1 - 5.8e-18 64.8 0.0 1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EJP68120.1 - 0.00023 20.9 0.1 0.00041 20.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 IF-2B PF01008.17 EJP68121.1 - 4.2e-80 269.0 1.1 4.9e-80 268.7 1.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family TRAPPC10 PF12584.8 EJP68122.1 - 2.9e-25 88.8 0.0 5.4e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_8 PF13181.6 EJP68122.1 - 0.27 11.6 0.7 0.79 10.1 0.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EJP68122.1 - 0.51 10.3 1.7 1.5 8.7 1.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat NDUF_B8 PF05821.11 EJP68124.1 - 6.8e-10 39.1 0.4 7.9e-10 38.9 0.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 EJP68125.1 - 9.1e-67 225.2 0.4 1.6e-66 224.5 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP68125.1 - 9.1e-19 67.9 0.0 6.5e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP68125.1 - 5.2e-10 39.6 0.0 1.6e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJP68125.1 - 0.00064 19.5 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.13 EJP68125.1 - 0.006 16.9 3.2 0.006 16.9 3.2 2.4 2 0 0 2 2 2 1 HSA HDA2-3 PF11496.8 EJP68125.1 - 0.011 14.9 0.3 0.85 8.7 0.0 2.6 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.25 EJP68126.1 - 1.4e-66 224.6 0.0 1.9e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP68126.1 - 2.2e-39 135.3 0.0 3.2e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP68126.1 - 4.6e-09 36.0 0.0 3.4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EJP68126.1 - 0.00025 20.1 0.5 0.00025 20.1 0.5 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EJP68126.1 - 0.03 14.3 2.6 0.037 14.0 0.2 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP68126.1 - 0.37 10.3 2.4 0.67 9.5 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ilm1 PF10311.9 EJP68128.1 - 4.8e-61 205.2 0.0 5.4e-61 205.0 0.0 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF3425 PF11905.8 EJP68129.1 - 2.9e-13 49.9 0.0 6.1e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) LIP PF03583.14 EJP68130.1 - 2.6e-82 276.4 0.0 3.7e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EJP68130.1 - 0.0024 17.4 0.1 0.26 10.7 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EJP68130.1 - 0.0056 16.3 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tau95 PF09734.9 EJP68131.1 - 0.17 12.7 0.2 0.34 11.7 0.2 1.6 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF4407 PF14362.6 EJP68132.1 - 0.15 11.4 4.1 0.25 10.7 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SOCS PF12610.8 EJP68132.1 - 0.55 10.7 3.6 20 5.7 0.0 2.9 3 0 0 3 3 3 0 Suppressor of cytokine signalling FUSC PF04632.12 EJP68132.1 - 0.96 7.9 8.4 0.23 10.0 5.0 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family MFS_1 PF07690.16 EJP68134.1 - 6.1e-33 114.2 40.0 6.1e-33 114.2 40.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68134.1 - 7.9e-11 41.5 6.3 7.9e-11 41.5 6.3 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP68134.1 - 9.2e-07 27.6 4.8 1.9e-06 26.6 4.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M56 PF05569.11 EJP68134.1 - 9.1 5.4 9.6 0.69 9.0 1.8 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 LIP PF03583.14 EJP68135.1 - 1.1e-50 172.6 0.0 1.7e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase WD40_3 PF15911.5 EJP68135.1 - 0.0022 17.9 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Abhydrolase_6 PF12697.7 EJP68135.1 - 0.025 15.2 0.6 0.053 14.1 0.6 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Asp PF00026.23 EJP68136.1 - 2.1e-63 214.6 1.5 2.8e-63 214.2 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP68136.1 - 5.4e-10 39.8 1.1 0.0009 19.5 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP68136.1 - 0.00018 22.1 0.1 0.035 14.7 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 EJP68136.1 - 0.0025 17.6 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Dynamin_N PF00350.23 EJP68137.1 - 1.4e-31 109.8 0.0 5e-31 108.0 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EJP68137.1 - 5.8e-17 61.8 0.0 9.8e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EJP68137.1 - 1.5e-05 25.1 0.0 0.00013 22.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EJP68137.1 - 0.046 14.2 0.0 0.21 12.1 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 EJP68137.1 - 0.16 11.8 0.0 0.65 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Erv26 PF04148.13 EJP68139.1 - 1.1e-93 312.8 0.1 1.2e-93 312.6 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 WBS_methylT PF12589.8 EJP68140.1 - 3.6e-15 56.5 4.2 6.8e-15 55.6 4.2 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EJP68140.1 - 3.1e-11 43.8 0.0 5.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP68140.1 - 6.3e-10 39.6 0.0 1.6e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EJP68140.1 - 0.00019 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EJP68140.1 - 0.00033 21.3 0.0 0.0014 19.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP68140.1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJP68140.1 - 0.0068 15.7 0.0 0.04 13.2 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 EJP68140.1 - 0.036 13.4 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_23 PF13489.6 EJP68140.1 - 0.064 13.1 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EJP68140.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA-synt_2 PF00152.20 EJP68141.1 - 6e-76 255.5 0.1 8.3e-76 255.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJP68141.1 - 8.2e-10 38.5 0.0 2.1e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EJP68141.1 - 6.7e-07 29.0 0.5 0.0041 16.6 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Hydrolase_4 PF12146.8 EJP68142.1 - 2.9e-08 33.3 0.0 5.6e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP68142.1 - 1.7e-06 28.8 0.1 2.5e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EJP68142.1 - 4.3e-05 23.3 0.2 0.00024 20.8 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EJP68142.1 - 7.3e-05 22.4 0.3 0.00024 20.7 0.3 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EJP68142.1 - 0.00021 20.9 0.4 0.035 13.6 0.3 2.7 2 2 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 EJP68142.1 - 0.00024 21.1 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EJP68142.1 - 0.0006 18.6 0.0 0.0011 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.13 EJP68142.1 - 0.019 13.5 0.1 0.34 9.4 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Amino_oxidase PF01593.24 EJP68143.1 - 6.3e-46 157.6 0.0 9.8e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP68143.1 - 1.9e-09 37.6 0.3 1.6e-08 34.7 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP68143.1 - 4.6e-06 26.5 0.0 1.6e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP68143.1 - 0.012 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EJP68143.1 - 0.087 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP68143.1 - 0.22 10.7 0.1 0.41 9.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain GFA PF04828.14 EJP68144.1 - 2.8e-24 85.3 0.5 3.8e-24 84.8 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Iso_dh PF00180.20 EJP68145.1 - 2.2e-81 273.7 0.0 2.7e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.25 EJP68146.1 - 5.7e-69 232.4 0.0 1.2e-68 231.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP68146.1 - 5.7e-51 173.3 0.0 1.5e-50 171.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP68146.1 - 0.00062 18.7 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EJP68146.1 - 0.0012 18.2 0.0 0.023 14.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Thioredoxin_7 PF13899.6 EJP68147.1 - 1.3e-15 57.3 0.0 3.9e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 EJP68147.1 - 4.5e-13 48.8 0.0 8.5e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EJP68147.1 - 1.8e-07 31.2 0.0 3.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 EJP68147.1 - 0.029 14.3 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 EJP68147.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Sugar_tr PF00083.24 EJP68148.1 - 8.1e-108 361.2 20.8 9.2e-108 361.0 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP68148.1 - 4.9e-17 61.9 48.2 1.6e-10 40.4 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 EJP68148.1 - 0.057 13.3 0.9 0.18 11.7 0.9 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain Acetyltransf_1 PF00583.25 EJP68149.1 - 8.4e-07 29.2 0.0 1.2e-06 28.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP68149.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP68149.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SOR_SNZ PF01680.17 EJP68151.1 - 1.7e-105 351.3 8.1 2.2e-105 350.9 8.1 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EJP68151.1 - 2e-09 37.2 4.6 3.4e-07 29.9 0.2 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EJP68151.1 - 0.00067 18.8 0.7 0.38 9.8 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EJP68151.1 - 0.00088 18.8 0.6 0.072 12.5 0.0 2.8 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 EJP68151.1 - 0.0009 18.5 0.1 0.033 13.4 0.0 2.5 2 2 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 EJP68151.1 - 0.0056 15.9 0.9 0.12 11.5 0.0 2.7 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 EJP68151.1 - 0.0064 16.5 0.0 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TMP-TENI PF02581.17 EJP68151.1 - 0.018 14.4 1.5 0.4 10.0 0.2 2.5 2 0 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 EJP68151.1 - 0.12 11.8 9.6 0.19 11.1 1.9 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase SNO PF01174.19 EJP68152.1 - 1e-55 188.5 0.0 1.1e-54 185.1 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EJP68152.1 - 4e-08 33.1 0.0 8.2e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EJP68152.1 - 0.0022 17.8 0.0 0.019 14.7 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 EJP68152.1 - 0.015 15.1 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.17 EJP68152.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 RRM_1 PF00076.22 EJP68153.1 - 4.9e-45 151.2 0.0 1.4e-16 60.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EJP68153.1 - 4e-06 26.7 0.2 0.0023 17.9 0.1 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EJP68153.1 - 0.00012 22.0 0.0 0.0018 18.3 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 EJP68153.1 - 0.00013 22.0 0.1 0.054 13.6 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 EJP68153.1 - 0.00029 20.6 0.0 0.051 13.4 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EJP68153.1 - 0.036 13.7 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ecm29 PF13001.7 EJP68154.1 - 7.6e-145 483.4 2.8 2.4e-144 481.7 1.3 2.6 3 0 0 3 3 3 1 Proteasome stabiliser IFRD PF05004.13 EJP68154.1 - 0.12 11.5 4.2 3.1 6.8 0.0 4.9 5 1 0 5 5 5 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 EJP68154.1 - 1.7 9.2 13.0 28 5.3 0.1 7.3 7 1 0 7 7 7 0 HEAT-like repeat MFS_1 PF07690.16 EJP68155.1 - 1.1e-36 126.6 38.1 1.1e-36 126.6 38.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68155.1 - 3.9e-17 62.3 5.6 3.9e-17 62.3 5.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2214 PF09980.9 EJP68155.1 - 0.038 13.8 0.3 0.038 13.8 0.3 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2214) Peptidase_M20 PF01546.28 EJP68156.1 - 3.2e-30 105.4 0.3 5.3e-30 104.7 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJP68156.1 - 9.8e-09 35.1 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EJP68156.1 - 0.00025 20.8 0.0 0.00065 19.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 ABC_tran PF00005.27 EJP68157.1 - 3.3e-33 115.1 0.0 7.1e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EJP68157.1 - 9.4e-22 77.9 7.7 1.4e-21 77.4 7.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 EJP68157.1 - 6.8e-05 23.3 0.6 0.00021 21.7 0.6 1.8 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EJP68157.1 - 0.00021 20.8 0.0 0.048 13.1 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJP68157.1 - 0.0019 18.5 0.1 0.01 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EJP68157.1 - 0.0026 17.5 0.0 0.0026 17.5 0.0 1.7 3 0 0 3 3 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EJP68157.1 - 0.0033 17.4 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 EJP68157.1 - 0.0077 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 EJP68157.1 - 0.0078 15.8 0.1 0.95 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EJP68157.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP68157.1 - 0.015 15.0 2.6 0.015 15.0 0.1 2.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain G-alpha PF00503.20 EJP68157.1 - 0.033 13.3 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 EJP68157.1 - 0.038 13.7 0.0 0.09 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EJP68157.1 - 0.039 13.7 1.0 0.25 11.0 1.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EJP68157.1 - 0.048 14.2 1.0 0.095 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EJP68157.1 - 0.05 13.9 0.1 0.57 10.5 0.1 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit KdpD PF02702.17 EJP68157.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Sigma54_activat PF00158.26 EJP68157.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Cas_Cmr5 PF09701.10 EJP68157.1 - 0.13 12.5 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) TsaE PF02367.17 EJP68157.1 - 0.15 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 EJP68157.1 - 0.15 12.1 1.1 0.2 11.7 0.1 1.6 2 0 0 2 2 1 0 Helicase HerA, central domain NOA36 PF06524.12 EJP68157.1 - 2.2 7.5 6.4 4.4 6.6 6.4 1.4 1 0 0 1 1 1 0 NOA36 protein AAA_18 PF13238.6 EJP68157.1 - 3.5 8.2 4.8 1.2 9.7 0.1 2.6 3 1 0 3 3 2 0 AAA domain ThrE PF06738.12 EJP68158.1 - 5.6e-72 242.0 6.5 1.6e-68 230.6 1.8 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EJP68158.1 - 3.2e-06 27.3 1.3 3.2e-06 27.3 1.3 3.4 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE HPP PF04982.13 EJP68159.1 - 6.5e-39 132.9 6.3 6.5e-39 132.9 6.3 2.0 2 0 0 2 2 2 1 HPP family Peptidase_C48 PF02902.19 EJP68160.1 - 2.4e-18 66.8 0.0 4.6e-18 65.9 0.0 1.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MlrC_C PF07171.12 EJP68160.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 MlrC C-terminus SLX9 PF15341.6 EJP68161.1 - 1.7e-35 122.3 4.5 2.3e-35 121.8 4.5 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF1348 PF07080.11 EJP68162.1 - 6.3e-64 213.7 8.8 7.4e-64 213.5 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EJP68162.1 - 6.1e-08 33.2 2.3 8.1e-08 32.8 2.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EJP68162.1 - 1.6e-05 25.2 0.3 2.3e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 EJP68162.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase ThiF PF00899.21 EJP68163.1 - 5.1e-61 206.1 0.0 7.2e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EJP68163.1 - 9.7e-12 45.4 0.0 4.7e-11 43.1 0.0 2.1 3 0 0 3 3 3 1 Rhodanese-like domain Shikimate_DH PF01488.20 EJP68163.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Filament PF00038.21 EJP68163.1 - 0.081 12.5 2.0 0.12 11.9 2.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein UDPG_MGDP_dh_N PF03721.14 EJP68163.1 - 0.093 12.3 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Csm1_N PF18504.1 EJP68163.1 - 0.13 12.6 3.6 0.66 10.4 3.2 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain NAD_binding_7 PF13241.6 EJP68163.1 - 0.13 12.7 0.0 0.34 11.4 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding PRKG1_interact PF15898.5 EJP68163.1 - 0.18 12.7 1.2 0.35 11.8 1.2 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain GPS2_interact PF15784.5 EJP68163.1 - 0.22 12.0 4.5 0.29 11.6 1.4 2.5 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain TMF_DNA_bd PF12329.8 EJP68163.1 - 0.61 10.1 3.5 1 9.4 3.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.12 EJP68163.1 - 3.7 7.6 5.1 17 5.5 5.1 2.1 1 1 0 1 1 1 0 Viral A-type inclusion protein repeat Pam17 PF08566.10 EJP68164.1 - 4e-62 208.9 0.0 5.5e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF389 PF04087.14 EJP68164.1 - 0.062 13.3 3.6 0.12 12.4 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF389) TPPK_C PF12555.8 EJP68164.1 - 0.14 12.3 1.8 6 7.0 0.1 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal APH PF01636.23 EJP68165.1 - 9.7e-06 25.7 0.5 0.00011 22.3 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Enterotoxin_a PF01375.17 EJP68166.1 - 3.9e-47 161.0 0.0 6.8e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain Chromo PF00385.24 EJP68167.1 - 1.7e-09 37.4 0.2 1.1e-08 34.9 0.3 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AIG2_2 PF13772.6 EJP68169.1 - 1.3e-05 25.5 0.0 2.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family Tannase PF07519.11 EJP68171.1 - 2.1e-101 340.2 2.3 2.7e-101 339.8 2.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Enterotoxin_a PF01375.17 EJP68172.1 - 2.7e-11 43.6 0.0 6.1e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain NAD_Gly3P_dh_N PF01210.23 EJP68173.1 - 1.3e-44 151.9 0.0 2.2e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EJP68173.1 - 1.1e-39 135.9 0.1 1.9e-39 135.2 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus HTH_ParB PF17762.1 EJP68173.1 - 0.11 12.3 0.2 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 HTH domain found in ParB protein Hydrophobin_2 PF06766.11 EJP68175.1 - 3.2e-29 100.7 10.5 4e-29 100.4 10.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CdiA_C PF18451.1 EJP68175.1 - 0.088 13.0 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain Ferric_reduct PF01794.19 EJP68176.1 - 2e-23 82.9 13.3 2e-23 82.9 13.3 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EJP68176.1 - 3.2e-11 43.3 0.0 5.2e-10 39.4 0.0 2.4 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 EJP68176.1 - 9.6e-10 38.8 0.0 0.00013 22.1 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EJP68176.1 - 0.0029 18.2 0.0 0.0079 16.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DJ-1_PfpI PF01965.24 EJP68177.1 - 1.3e-11 44.5 0.0 1.7e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family NmrA PF05368.13 EJP68178.1 - 4.5e-05 23.1 0.2 0.0025 17.4 0.3 2.1 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EJP68178.1 - 0.00082 19.3 1.6 0.00082 19.3 1.6 2.2 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EJP68178.1 - 0.0019 17.7 0.1 0.0026 17.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EJP68178.1 - 0.0096 16.4 0.3 0.024 15.1 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EJP68178.1 - 0.026 14.7 0.9 0.1 12.7 0.3 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 EJP68178.1 - 0.061 13.4 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EJP68178.1 - 0.097 13.3 0.3 0.22 12.1 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent hDGE_amylase PF14701.6 EJP68179.1 - 2.8e-175 583.7 0.0 3.8e-175 583.2 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EJP68179.1 - 1e-118 396.6 0.1 2.7e-118 395.2 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EJP68179.1 - 3.7e-86 288.9 0.0 8.1e-86 287.8 0.0 1.6 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EJP68179.1 - 2.1e-31 107.9 0.0 4.6e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme RCR PF12273.8 EJP68180.1 - 0.0059 17.3 0.5 0.011 16.4 0.5 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.11 EJP68180.1 - 0.012 15.5 0.7 0.023 14.7 0.7 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4381 PF14316.6 EJP68180.1 - 0.043 14.0 1.4 0.071 13.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FAM209 PF15206.6 EJP68180.1 - 0.052 13.4 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 FAM209 family TMEM154 PF15102.6 EJP68180.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 TMEM154 protein family SCF PF02404.15 EJP68180.1 - 0.11 11.8 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Stem cell factor UPF0370 PF13980.6 EJP68180.1 - 0.95 9.5 3.7 1.6 8.8 3.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) RSN1_7TM PF02714.15 EJP68181.1 - 3.7e-75 252.8 18.5 3.7e-75 252.8 18.5 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EJP68181.1 - 3.6e-35 121.0 0.9 3.6e-35 121.0 0.9 2.4 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EJP68181.1 - 7.4e-35 120.8 0.0 1.1e-34 120.2 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter p450 PF00067.22 EJP68182.1 - 8.7e-36 123.6 0.0 1.2e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 EJP68184.1 - 1.6e-07 31.5 0.5 2.3e-07 31.0 0.5 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP68184.1 - 0.09 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase TRF PF08558.10 EJP68185.1 - 2.3e-15 56.9 0.0 4e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EJP68185.1 - 5.9e-05 23.2 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP68185.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Glyco_hydro_72 PF03198.14 EJP68186.1 - 7.1e-98 327.7 0.4 1.1e-97 327.2 0.4 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 EJP68186.1 - 0.033 13.3 0.2 0.12 11.5 0.1 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain GP24_25 PF17388.2 EJP68186.1 - 0.15 12.1 0.0 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 Pro-rich_19 PF15455.6 EJP68186.1 - 0.32 10.1 1.0 0.48 9.5 1.0 1.2 1 0 0 1 1 1 0 Proline-rich 19 adh_short PF00106.25 EJP68187.1 - 1.9e-38 131.9 0.2 2.7e-38 131.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP68187.1 - 7.3e-33 114.1 0.1 1e-32 113.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP68187.1 - 9.7e-09 35.4 3.3 1.1e-07 31.9 3.3 2.1 1 1 0 1 1 1 1 KR domain Neugrin PF06413.11 EJP68188.1 - 5e-11 43.0 0.3 5e-11 43.0 0.3 2.6 3 0 0 3 3 3 1 Neugrin MRP-L20 PF12824.7 EJP68188.1 - 0.00039 20.6 5.7 0.00039 20.6 5.7 2.5 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 CcdA PF07362.12 EJP68188.1 - 0.041 14.3 0.4 0.041 14.3 0.4 2.7 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA Calcipressin PF04847.12 EJP68189.1 - 1.7e-48 164.8 0.0 2.1e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Calcipressin PCNP PF15473.6 EJP68189.1 - 0.12 13.1 0.2 0.25 12.1 0.2 1.4 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family tRNA-synt_2d PF01409.20 EJP68190.1 - 1.4e-46 159.0 1.4 8.7e-25 87.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EJP68190.1 - 1e-26 93.2 0.0 2.6e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.27 EJP68191.1 - 9.1e-55 182.6 1.1 9.7e-20 70.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PNP_UDP_1 PF01048.20 EJP68192.1 - 9.2e-09 34.9 0.4 2.6e-08 33.4 0.4 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_12 PF13424.6 EJP68193.1 - 3.4e-27 94.5 6.9 3.4e-16 59.3 0.7 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EJP68193.1 - 2.7e-19 68.4 3.6 6.1e-14 51.4 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJP68193.1 - 5.4e-12 45.0 1.4 7.2e-05 22.4 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP68193.1 - 1.1e-10 40.8 0.5 0.00038 20.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP68193.1 - 7.8e-09 35.1 0.3 0.0055 16.8 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJP68193.1 - 1.8e-08 33.9 1.5 0.0097 16.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP68193.1 - 3.6e-08 33.1 0.1 7.6e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 EJP68193.1 - 3e-07 30.7 6.2 0.03 15.1 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJP68193.1 - 0.00095 19.8 3.8 0.71 10.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EJP68193.1 - 0.0012 19.2 0.3 0.4 11.4 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EJP68193.1 - 0.0016 18.7 2.0 1.2 9.6 0.0 3.6 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP68193.1 - 0.0026 18.2 0.5 0.014 15.9 0.2 2.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 EJP68193.1 - 0.0082 15.9 0.5 0.82 9.4 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 EJP68193.1 - 0.01 15.6 0.1 0.093 12.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_11 PF13414.6 EJP68193.1 - 0.019 14.6 0.2 1.4 8.7 0.0 3.0 2 1 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 EJP68193.1 - 0.025 15.2 2.9 1.7 9.4 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat NB-ARC PF00931.22 EJP68193.1 - 0.23 10.6 0.0 0.4 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Fungal_trans PF04082.18 EJP68194.1 - 2.4e-18 66.2 0.0 3.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 EJP68195.1 - 2.8e-08 34.0 0.0 3.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP68195.1 - 5.4e-06 26.4 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP68195.1 - 5.6e-06 26.7 0.0 7.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP68195.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EJP68195.1 - 0.011 16.4 0.0 0.018 15.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EJP68195.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Metal_CEHH PF14455.6 EJP68195.1 - 0.045 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Predicted metal binding domain LAL_C2 PF18603.1 EJP68195.1 - 0.075 13.2 0.0 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 RNA_pol_A_bac PF01000.26 EJP68196.1 - 3.5e-33 114.3 0.0 5.6e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EJP68196.1 - 1.6e-18 65.9 0.0 2e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.32 EJP68197.1 - 2.9e-31 107.0 6.3 1.5e-05 25.7 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.14 EJP68197.1 - 3.7e-31 107.2 15.7 3.7e-31 107.2 15.7 1.8 2 0 0 2 2 2 1 Sof1-like domain ANAPC4_WD40 PF12894.7 EJP68197.1 - 3.3e-09 36.9 0.3 0.4 11.0 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP68197.1 - 1.9e-06 27.1 0.0 0.019 13.9 0.0 3.3 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EJP68197.1 - 0.0009 17.9 0.6 0.7 8.4 0.0 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.11 EJP68197.1 - 0.0017 18.2 0.2 0.027 14.4 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 EJP68197.1 - 0.0044 17.0 0.0 7.4 6.7 0.0 4.3 2 2 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region 6PF2K PF01591.18 EJP68198.1 - 3e-66 222.9 0.0 1.1e-46 159.0 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EJP68198.1 - 4.7e-29 101.5 0.0 6.2e-24 84.8 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 EJP68198.1 - 0.015 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 EJP68198.1 - 0.025 14.7 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoU PF01895.19 EJP68198.1 - 0.054 14.0 0.4 0.49 10.9 0.0 2.4 2 0 0 2 2 2 0 PhoU domain dCMP_cyt_deam_1 PF00383.23 EJP68199.1 - 1.1e-08 34.8 0.5 2.9e-08 33.5 0.5 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EJP68199.1 - 0.00071 19.3 0.3 0.002 17.9 0.1 1.8 2 0 0 2 2 2 1 MafB19-like deaminase RNase_H PF00075.24 EJP68200.1 - 3.7e-38 130.9 0.0 6.1e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 EJP68200.1 - 1.3e-33 115.0 9.0 1e-16 60.9 1.2 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin Na_H_Exchanger PF00999.21 EJP68201.1 - 2e-46 158.5 15.5 2.5e-46 158.2 15.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EJP68201.1 - 0.14 12.2 0.1 0.61 10.2 0.1 2.1 1 0 0 1 1 1 0 YrhC-like protein ADH_N PF08240.12 EJP68202.1 - 9.7e-09 35.1 0.0 2.7e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP68202.1 - 1.2e-08 35.0 0.0 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EJP68202.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Fungal_trans PF04082.18 EJP68205.1 - 7.8e-09 34.9 0.1 3e-08 33.0 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.21 EJP68206.1 - 1.4e-79 267.6 0.0 1.8e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EJP68206.1 - 0.00027 20.2 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.22 EJP68207.1 - 9.8e-07 28.5 0.1 1.7e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EJP68207.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AGOG PF09171.10 EJP68207.1 - 0.032 13.5 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 N-glycosylase/DNA lyase DMAP_binding PF06464.11 EJP68207.1 - 0.082 13.7 1.6 0.37 11.6 0.1 2.5 2 1 0 2 2 2 0 DMAP1-binding Domain DUF2046 PF09755.9 EJP68208.1 - 0.022 14.0 3.2 0.052 12.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) FlaC_arch PF05377.11 EJP68208.1 - 0.031 14.7 0.4 0.031 14.7 0.4 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 EJP68208.1 - 0.22 11.7 0.1 0.22 11.7 0.1 3.1 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) GreA_GreB_N PF03449.15 EJP68208.1 - 0.38 10.9 5.2 0.2 11.8 1.5 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal LtuB PF17455.2 EJP68208.1 - 0.58 10.8 1.8 0.73 10.5 0.5 1.8 2 0 0 2 2 2 0 Late transcription unit B DUF2457 PF10446.9 EJP68209.1 - 0.00075 18.8 9.5 0.0014 17.9 9.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RXT2_N PF08595.11 EJP68209.1 - 0.0084 16.2 0.8 0.0084 16.2 0.8 1.8 2 0 0 2 2 2 1 RXT2-like, N-terminal CcmD PF04995.14 EJP68209.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.3 2 1 0 2 2 2 0 Heme exporter protein D (CcmD) ZapB PF06005.12 EJP68209.1 - 2.4 8.7 7.9 1.2 9.6 4.0 2.2 1 1 1 2 2 2 0 Cell division protein ZapB GCIP PF13324.6 EJP68209.1 - 4.4 6.8 10.1 0.47 10.0 2.8 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting FAM176 PF14851.6 EJP68209.1 - 7.6 6.2 6.8 0.9 9.2 1.5 2.1 2 0 0 2 2 2 0 FAM176 family HgmA PF04209.13 EJP68213.1 - 1.8e-187 623.3 0.0 2e-187 623.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase OPT PF03169.15 EJP68214.1 - 4.1e-169 564.1 50.8 4.7e-169 563.9 50.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ank_2 PF12796.7 EJP68216.1 - 1.6e-29 102.3 0.7 1.9e-09 38.0 0.0 7.4 8 2 0 8 8 8 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP68216.1 - 4e-25 85.1 9.2 0.00066 19.9 0.1 12.4 13 1 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.6 EJP68216.1 - 7.6e-25 87.0 6.1 3.2e-10 40.3 0.0 9.3 6 2 5 11 11 11 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP68216.1 - 7.8e-24 83.4 7.0 5.2e-06 26.6 0.0 7.9 5 3 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EJP68216.1 - 1.3e-20 72.9 8.6 0.00072 19.9 0.0 9.9 11 0 0 11 11 11 4 Ankyrin repeat UQ_con PF00179.26 EJP68218.1 - 8.3e-21 74.1 0.1 1.2e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme gpUL132 PF11359.8 EJP68218.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Prok-E2_B PF14461.6 EJP68218.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Bac_surface_Ag PF01103.23 EJP68219.1 - 1.4e-35 123.3 0.0 1.8e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Acetyltransf_7 PF13508.7 EJP68221.1 - 6e-07 29.8 0.1 9.4e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP68221.1 - 1.6e-06 28.3 0.1 9.6e-06 25.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EJP68221.1 - 0.0014 18.5 0.1 0.049 13.6 0.0 2.6 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 EJP68221.1 - 0.0022 17.9 0.1 0.066 13.1 0.1 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Vint PF14623.6 EJP68222.1 - 6.5e-60 201.7 0.0 1.3e-59 200.7 0.0 1.5 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.6 EJP68222.1 - 3e-29 100.9 0.0 5.3e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 EJP68222.1 - 3e-10 40.6 0.0 6.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EJP68222.1 - 3.2e-10 40.2 0.0 7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EJP68222.1 - 6.3e-08 33.2 0.1 3.1e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Hint PF01079.20 EJP68222.1 - 0.043 13.3 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Hint module DUF1400 PF07176.11 EJP68222.1 - 0.067 13.5 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Thiolase_N PF00108.23 EJP68223.1 - 5.4e-67 225.9 3.1 7e-67 225.5 3.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EJP68223.1 - 1.1e-38 131.7 3.5 1.3e-38 131.4 0.8 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EJP68223.1 - 0.00087 18.9 3.9 0.001 18.7 2.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HTH_31 PF13560.6 EJP68223.1 - 0.069 13.5 2.5 8.1 6.9 0.0 3.9 4 0 0 4 4 4 0 Helix-turn-helix domain YabA PF06156.13 EJP68224.1 - 0.0047 17.6 3.2 2.7 8.7 0.7 2.6 2 0 0 2 2 2 2 Initiation control protein YabA NEMO PF11577.8 EJP68224.1 - 0.12 12.4 2.4 36 4.5 0.0 3.6 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO Yuri_gagarin PF15934.5 EJP68224.1 - 0.25 11.1 5.8 8.9 6.1 5.8 2.3 1 1 0 1 1 1 0 Yuri gagarin Cep57_CLD_2 PF14197.6 EJP68224.1 - 1.7 8.8 8.7 0.6 10.2 3.9 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 EJP68224.1 - 6.1 7.4 8.7 1.5 9.3 1.5 2.7 2 1 0 2 2 2 0 Cell division protein ZapB Egh16-like PF11327.8 EJP68225.1 - 1.9e-67 227.3 9.0 3.9e-67 226.2 9.0 1.5 1 1 0 1 1 1 1 Egh16-like virulence factor TraT PF05818.12 EJP68225.1 - 10 5.8 8.9 18 5.0 8.9 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Fungal_trans_2 PF11951.8 EJP68226.1 - 3.5e-27 95.2 2.6 4.9e-27 94.7 2.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 EJP68227.1 - 5.2e-149 496.8 42.7 6e-149 496.6 42.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SAYSvFN PF10260.9 EJP68227.1 - 0.24 11.4 7.6 3.1 7.8 0.3 3.3 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) IBN_N PF03810.19 EJP68228.1 - 9.6e-12 44.6 0.1 2e-10 40.4 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 EJP68228.1 - 0.0077 16.4 0.5 1.2 9.6 0.1 4.2 3 0 0 3 3 3 1 HEAT repeat Xpo1 PF08389.12 EJP68228.1 - 0.01 15.9 0.0 0.058 13.5 0.0 2.5 1 0 0 1 1 1 1 Exportin 1-like protein SQS_PSY PF00494.19 EJP68228.1 - 0.082 12.4 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Squalene/phytoene synthase PI3Ka PF00613.20 EJP68228.1 - 0.17 11.3 1.4 1.8 7.9 1.4 2.3 1 1 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI31_Prot_N PF11566.8 EJP68229.1 - 8.1e-49 165.6 0.0 1.1e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EJP68229.1 - 5.8e-19 69.1 20.7 5.8e-19 69.1 20.7 2.6 3 1 0 3 3 3 1 PI31 proteasome regulator MS_channel PF00924.18 EJP68231.1 - 6.9e-20 71.5 1.8 1.2e-19 70.6 1.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EJP68231.1 - 0.003 17.0 0.1 0.0084 15.6 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EJP68231.1 - 0.044 13.7 0.1 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain FA_desaturase PF00487.24 EJP68231.1 - 0.98 9.2 3.8 10 5.8 1.1 2.3 2 0 0 2 2 2 0 Fatty acid desaturase Sugar_tr PF00083.24 EJP68232.1 - 3.6e-91 306.3 18.7 4.4e-91 306.0 18.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP68232.1 - 8.7e-15 54.5 43.3 4.2e-09 35.8 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abp2 PF09441.10 EJP68233.1 - 4.7e-82 274.1 0.0 7.7e-82 273.4 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 Sds3 PF08598.11 EJP68235.1 - 1.7e-25 90.3 5.5 2.3e-25 89.9 5.5 1.3 1 0 0 1 1 1 1 Sds3-like 2CSK_N PF08521.10 EJP68236.1 - 0.0014 18.7 0.1 0.0027 17.8 0.1 1.4 1 0 0 1 1 1 1 Two-component sensor kinase N-terminal COG5 PF10392.9 EJP68236.1 - 0.004 17.3 1.0 0.039 14.1 0.0 2.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 EJP68236.1 - 0.48 10.4 4.2 0.75 9.8 2.9 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 EJP68236.1 - 1.2 8.2 5.2 1.2 8.2 0.8 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ala_racemase_N PF01168.20 EJP68237.1 - 7e-24 84.7 0.1 8.4e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 EJP68238.1 - 3.2e-125 418.7 10.6 4.2e-125 418.3 10.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EJP68238.1 - 6.3e-47 158.5 0.0 1.9e-46 156.9 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EJP68238.1 - 3.5e-17 62.7 0.0 7.5e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EJP68238.1 - 6.3e-05 23.1 1.3 0.04 14.0 0.0 3.0 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EJP68238.1 - 0.038 14.2 0.1 0.18 12.0 0.1 2.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Methyltransf_11 PF08241.12 EJP68239.1 - 6e-11 42.8 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP68239.1 - 2.6e-09 37.1 0.0 4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP68239.1 - 4.2e-09 37.1 0.0 7.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP68239.1 - 4.7e-08 33.6 0.0 1.6e-07 31.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP68239.1 - 3.7e-06 26.8 0.0 8.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP68239.1 - 0.038 13.3 0.0 0.082 12.2 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family P16-Arc PF04699.14 EJP68240.1 - 1.7e-51 174.6 0.0 2e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Peptidase_C14 PF00656.22 EJP68241.1 - 7.5e-42 144.0 0.0 9.3e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Caspase domain LysM PF01476.20 EJP68242.1 - 6.3e-26 90.2 0.8 0.00038 20.5 0.0 5.2 5 0 0 5 5 5 5 LysM domain UPF0203 PF05254.12 EJP68242.1 - 0.00019 21.6 12.6 0.38 11.0 0.1 5.3 4 3 0 4 4 4 2 Uncharacterised protein family (UPF0203) Rab15_effector PF15208.6 EJP68242.1 - 0.00045 19.6 0.7 2.5 7.4 0.0 3.8 1 1 3 4 4 4 1 Rab15 effector HAP2-GCS1 PF10699.9 EJP68242.1 - 0.0063 16.5 14.3 2.7 8.0 0.2 5.1 5 0 0 5 5 5 3 Male gamete fusion factor NLPC_P60 PF00877.19 EJP68242.1 - 0.09 12.8 3.4 11 6.1 0.0 3.5 4 0 0 4 4 4 0 NlpC/P60 family zf-TFIIB PF13453.6 EJP68242.1 - 0.27 10.6 6.0 23 4.4 0.1 4.2 4 0 0 4 4 4 0 Transcription factor zinc-finger NDUFB10 PF10249.9 EJP68242.1 - 9.3 6.8 7.7 82 3.7 0.0 3.8 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase subunit 10 CN_hydrolase PF00795.22 EJP68243.1 - 2.5e-44 151.6 0.2 3e-44 151.3 0.2 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TAF4 PF05236.14 EJP68244.1 - 2.8e-26 92.9 6.4 4.2e-25 89.1 5.8 2.9 3 0 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family IHABP4_N PF16174.5 EJP68244.1 - 1.7 9.3 9.8 9.2 6.8 4.3 2.8 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal CPSF73-100_C PF11718.8 EJP68245.1 - 1.7e-85 286.0 0.0 2.5e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EJP68245.1 - 1.2e-29 102.8 0.0 2.5e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EJP68245.1 - 1.1e-18 67.4 0.1 2.1e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EJP68245.1 - 2.1e-18 67.1 0.7 4.8e-18 65.9 0.7 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EJP68245.1 - 2.3e-11 43.5 0.0 4.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EJP68245.1 - 7.1e-06 25.7 0.7 1.5e-05 24.6 0.7 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EJP68245.1 - 7.4e-06 26.0 0.1 1.7e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain V_ATPase_I PF01496.19 EJP68246.1 - 0 1032.7 0.0 0 1032.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 EJP68246.1 - 0.024 14.5 4.0 0.074 13.0 0.5 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ SesA PF17107.5 EJP68246.1 - 0.051 13.8 3.4 0.36 11.0 0.2 2.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1664 PF07889.12 EJP68246.1 - 0.084 12.9 3.9 1.9 8.6 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 EJP68246.1 - 0.099 12.2 1.4 2.5 7.6 0.1 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.20 EJP68246.1 - 0.14 12.1 6.2 2.2 8.3 0.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit Laminin_II PF06009.12 EJP68246.1 - 0.18 11.8 4.4 5 7.2 0.1 2.4 2 0 0 2 2 2 0 Laminin Domain II Golgin_A5 PF09787.9 EJP68246.1 - 0.21 11.0 7.1 0.11 11.9 0.8 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF1515 PF07439.11 EJP68246.1 - 0.23 11.5 1.5 0.5 10.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF639 PF04842.12 EJP68246.1 - 0.26 10.7 3.5 3.7 6.9 0.5 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Spc7 PF08317.11 EJP68246.1 - 0.3 9.9 6.7 2.5 6.9 1.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Serine_rich PF08824.10 EJP68246.1 - 0.36 10.8 2.9 0.77 9.7 0.2 2.3 2 0 0 2 2 2 0 Serine rich protein interaction domain Filament PF00038.21 EJP68246.1 - 0.45 10.0 11.8 0.88 9.1 1.0 2.5 2 1 0 2 2 2 0 Intermediate filament protein SKA2 PF16740.5 EJP68246.1 - 0.46 10.3 2.9 9.7 6.0 0.4 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3552 PF12072.8 EJP68246.1 - 0.48 9.8 3.8 5.4 6.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4763 PF15960.5 EJP68246.1 - 0.52 9.6 5.4 0.48 9.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) EzrA PF06160.12 EJP68246.1 - 1.4 7.0 7.7 4.3 5.4 0.3 2.3 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Rab5-bind PF09311.11 EJP68246.1 - 1.5 8.1 8.0 1.6 8.1 1.1 2.1 2 0 0 2 2 2 0 Rabaptin-like protein HMMR_N PF15905.5 EJP68246.1 - 2.6 7.4 7.0 10 5.5 1.9 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 EJP68246.1 - 2.8 8.0 8.7 2.9 8.0 1.8 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 EJP68246.1 - 2.8 8.0 7.2 1.9 8.5 1.5 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.6 EJP68246.1 - 4.6 7.7 6.3 9.8 6.7 1.1 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF16 PF01519.16 EJP68246.1 - 5 7.7 6.3 5.7 7.5 0.4 3.0 3 1 0 3 3 2 0 Protein of unknown function DUF16 Tropomyosin_1 PF12718.7 EJP68246.1 - 7.5 6.7 8.9 9.6 6.4 2.1 2.2 2 0 0 2 2 2 0 Tropomyosin like UPF0449 PF15136.6 EJP68246.1 - 9.3 6.8 7.5 7.6 7.1 0.3 2.9 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 OmpH PF03938.14 EJP68246.1 - 9.4 6.6 6.8 2.2 8.6 0.4 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) LRR_6 PF13516.6 EJP68247.1 - 0.00022 21.0 0.1 1.9 8.8 0.0 4.1 3 0 0 3 3 3 1 Leucine Rich repeat F-box-like PF12937.7 EJP68247.1 - 0.0026 17.6 0.0 0.011 15.6 0.0 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EJP68247.1 - 0.0056 17.1 0.5 0.55 10.7 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EJP68247.1 - 0.57 10.9 1.7 1.7e+02 3.4 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat adh_short PF00106.25 EJP68248.1 - 7.2e-11 41.9 0.0 1.1e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP68248.1 - 2.4e-07 30.6 0.1 2.9e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L24e PF01246.20 EJP68249.1 - 3.9e-32 110.3 5.1 8.8e-32 109.1 5.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e ING PF12998.7 EJP68250.1 - 9.3e-07 29.4 0.0 0.0017 18.9 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EJP68250.1 - 1.9e-06 27.7 8.7 3.1e-06 27.0 8.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EJP68250.1 - 0.24 11.7 1.5 0.49 10.7 1.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prenyltransf PF01255.19 EJP68251.1 - 5.2e-81 271.4 0.0 7.3e-81 271.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.24 EJP68251.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_hydro_63 PF03200.16 EJP68252.1 - 3.1e-09 36.1 9.6 3.8e-09 35.8 1.6 4.2 4 1 0 4 4 4 1 Glycosyl hydrolase family 63 C-terminal domain Hep_59 PF07052.11 EJP68252.1 - 0.041 14.6 0.1 0.1 13.4 0.1 1.6 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 TTSSLRR PF12468.8 EJP68252.1 - 0.075 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein OSCP PF00213.18 EJP68253.1 - 1.5e-47 161.9 0.4 1.8e-47 161.7 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF3823_C PF18003.1 EJP68253.1 - 0.092 13.5 0.3 0.15 12.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3823_C) Mob1_phocein PF03637.17 EJP68254.1 - 2.5e-69 232.6 0.0 3.7e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family DBR1 PF05011.13 EJP68255.1 - 1.4e-47 161.6 0.8 3.4e-46 157.1 0.0 2.2 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EJP68255.1 - 0.00062 20.3 0.4 0.0011 19.6 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FMN_red PF03358.15 EJP68256.1 - 6.8e-28 97.4 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EJP68256.1 - 1.9e-07 31.0 0.0 3.7e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin-like fold Methyltransf_23 PF13489.6 EJP68257.1 - 9.9e-18 64.5 0.0 1.6e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP68257.1 - 3.7e-09 37.2 0.0 1.2e-08 35.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP68257.1 - 2.9e-07 30.4 0.0 9.2e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP68257.1 - 7.5e-06 26.6 0.0 3.2e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP68257.1 - 2.7e-05 24.7 0.0 8.4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 EJP68257.1 - 0.00011 22.3 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EJP68257.1 - 0.00016 21.1 0.0 0.00049 19.5 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EJP68257.1 - 0.017 14.6 0.0 0.04 13.4 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 EJP68257.1 - 0.084 12.4 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Skp1_POZ PF03931.15 EJP68258.1 - 1.4e-06 28.4 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.22 EJP68259.1 - 2e-46 157.5 0.0 2.9e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP68259.1 - 2.4e-20 72.9 0.0 5.3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP68259.1 - 1.8e-05 24.3 0.0 4.9e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EJP68259.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EJP68259.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.10 EJP68260.1 - 3.5e-27 94.3 1.9 4.4e-27 94.0 1.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EJP68260.1 - 0.0087 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad4 Myb_DNA-binding PF00249.31 EJP68261.1 - 6.5e-12 45.5 0.0 7.8e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP68261.1 - 0.0014 18.9 0.3 0.81 10.0 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EJP68261.1 - 0.014 15.3 0.0 0.061 13.2 0.0 2.1 1 0 0 1 1 1 0 Myb DNA-binding like DS PF01916.17 EJP68262.1 - 1.8e-130 434.4 0.1 2.1e-130 434.2 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Aldo_ket_red PF00248.21 EJP68263.1 - 1.9e-20 73.3 0.0 4.5e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.22 EJP68264.1 - 6.1e-16 59.3 0.2 1.1e-15 58.5 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EJP68264.1 - 0.0041 17.8 0.2 0.0066 17.1 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EJP68264.1 - 0.039 14.4 0.0 0.075 13.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EJP68265.1 - 1.9e-08 34.9 0.0 2.5e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP68265.1 - 4.5e-08 33.6 0.0 1e-06 29.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP68265.1 - 8e-06 25.8 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP68265.1 - 2.5e-05 24.9 0.0 5.7e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP68265.1 - 9.2e-05 22.3 0.0 0.0097 15.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EJP68265.1 - 0.19 10.6 0.0 1.9 7.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Myb_DNA-binding PF00249.31 EJP68266.1 - 2.9e-13 49.8 4.5 1.1e-10 41.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP68266.1 - 2.7e-06 27.6 4.6 0.00015 21.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.25 EJP68268.1 - 2.4e-22 78.7 1.4 4.4e-22 77.9 1.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EJP68268.1 - 6.6e-19 68.2 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EJP68268.1 - 0.00087 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family T6_Ig_like PF18002.1 EJP68268.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 T6 antigen Ig like domain zf-RING_2 PF13639.6 EJP68269.1 - 1.2e-12 47.9 3.7 2.1e-12 47.2 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EJP68269.1 - 2.7e-10 39.8 1.3 4.8e-10 39.0 1.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EJP68269.1 - 5.8e-07 29.3 3.5 9.5e-07 28.6 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP68269.1 - 8.7e-07 28.7 2.1 1.6e-06 27.9 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EJP68269.1 - 5.6e-06 26.6 4.1 1.6e-05 25.1 4.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EJP68269.1 - 1.1e-05 25.1 3.8 2.5e-05 24.0 3.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EJP68269.1 - 3.6e-05 23.6 1.6 6.1e-05 22.9 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EJP68269.1 - 0.00056 19.7 1.4 0.00099 18.9 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJP68269.1 - 0.002 18.1 2.7 0.0021 18.0 1.5 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EJP68269.1 - 0.0042 17.1 1.1 0.0088 16.1 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 EJP68269.1 - 0.11 12.8 1.9 0.18 12.1 1.9 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EJP68269.1 - 0.38 10.6 7.4 0.11 12.3 2.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EJP68269.1 - 0.57 10.1 2.3 1.4 8.9 2.3 1.7 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_cc PF11790.8 EJP68271.1 - 2.1e-56 191.2 3.3 3.2e-56 190.6 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core ALF PF03752.13 EJP68271.1 - 0.052 13.5 0.7 2.5 8.2 0.0 2.8 2 0 0 2 2 2 0 Short repeats of unknown function SAP130_C PF16014.5 EJP68271.1 - 1.9 7.5 8.8 2.7 7.0 8.8 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus BTB PF00651.31 EJP68272.1 - 5.7e-10 39.4 0.0 3.1e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Zn_clus PF00172.18 EJP68273.1 - 5e-08 32.9 9.5 8.6e-08 32.2 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP68273.1 - 3e-07 29.6 0.3 4.9e-07 28.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_Eps PF04627.13 EJP68275.1 - 9.1e-24 83.2 2.9 1.3e-23 82.7 2.9 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.13 EJP68276.1 - 2.3e-48 163.9 0.6 1.2e-47 161.5 0.1 2.4 2 1 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mito_carr PF00153.27 EJP68277.1 - 1.6e-51 172.2 4.3 1.4e-16 60.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M50 PF02163.22 EJP68277.1 - 0.059 12.6 0.2 0.082 12.2 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M50 Tim17 PF02466.19 EJP68277.1 - 0.085 13.2 0.6 4.4 7.7 0.0 3.4 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family RhoGEF PF00621.20 EJP68279.1 - 1.3e-20 74.4 0.3 6e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 EJP68279.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF948 PF06103.11 EJP68279.1 - 0.12 12.6 0.6 0.52 10.6 0.6 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) 5_nucleotid PF05761.14 EJP68279.1 - 0.17 10.7 1.9 0.22 10.4 0.7 1.7 2 0 0 2 2 2 0 5' nucleotidase family ECH_2 PF16113.5 EJP68279.1 - 0.35 10.3 5.2 1 8.8 5.2 1.8 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Syntaxin_2 PF14523.6 EJP68279.1 - 0.76 10.2 8.0 0.5 10.8 3.0 2.7 1 1 1 2 2 2 0 Syntaxin-like protein Cep57_CLD_2 PF14197.6 EJP68279.1 - 2 8.6 18.2 3.9 7.6 2.8 2.8 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 OmpH PF03938.14 EJP68279.1 - 2.7 8.3 9.7 12 6.2 9.5 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CCDC-167 PF15188.6 EJP68279.1 - 5.7 7.4 8.5 17 5.8 8.5 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 3Beta_HSD PF01073.19 EJP68280.1 - 2.2e-11 43.3 0.0 3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EJP68280.1 - 2.9e-11 43.3 0.3 4.8e-11 42.6 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP68280.1 - 4.7e-07 29.9 0.9 2.5e-06 27.5 0.4 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EJP68280.1 - 3.2e-06 26.5 1.1 3.8e-05 23.0 1.1 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EJP68280.1 - 0.00054 19.9 0.8 0.0019 18.1 0.8 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EJP68280.1 - 0.00089 18.5 0.3 0.0013 17.9 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EJP68280.1 - 0.0011 18.4 0.2 0.0036 16.7 0.2 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 EJP68281.1 - 1.4e-08 34.2 0.4 3.3e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP68281.1 - 1.1e-07 31.9 12.7 1.9e-07 31.0 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EJP68282.1 - 0.0044 16.9 2.2 0.0059 16.5 0.1 2.2 3 0 0 3 3 3 1 F-box-like E1-E2_ATPase PF00122.20 EJP68283.1 - 9.2e-34 116.5 20.5 4.3e-29 101.3 0.1 3.7 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EJP68283.1 - 2.4e-21 76.3 6.4 2.4e-21 76.3 6.4 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EJP68283.1 - 4e-21 76.3 0.3 8e-17 62.2 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJP68283.1 - 2.2e-17 62.9 0.0 5.6e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EJP68283.1 - 2.3e-17 62.4 0.1 6e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP68283.1 - 8e-06 25.8 0.2 1.7e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 EJP68284.1 - 1.9e-33 115.8 0.4 2.5e-33 115.5 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP68284.1 - 1e-06 28.7 9.4 1.6e-06 28.1 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EJP68285.1 - 1e-05 25.7 11.9 0.00042 20.6 2.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP68285.1 - 2.8e-05 24.4 17.2 0.00057 20.2 2.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 EJP68285.1 - 0.022 15.2 2.2 0.097 13.1 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 EJP68285.1 - 0.031 14.2 6.9 0.034 14.1 1.5 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DCR PF14047.6 EJP68285.1 - 0.04 14.1 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Dppa2/4 conserved region zf-C2H2_4 PF13894.6 EJP68285.1 - 0.048 14.5 1.7 0.048 14.5 1.7 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EJP68285.1 - 0.098 12.8 1.7 9.7 6.4 0.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 EJP68285.1 - 0.1 12.6 0.8 0.1 12.6 0.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP68285.1 - 0.36 11.2 3.6 0.65 10.4 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TFIIA PF03153.13 EJP68285.1 - 4.2 7.3 10.9 4.6 7.1 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC144C PF14915.6 EJP68286.1 - 0.00011 21.4 1.4 0.00013 21.2 1.4 1.0 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DASH_Dad2 PF08654.10 EJP68286.1 - 0.032 14.6 1.8 0.083 13.3 0.2 2.1 2 1 1 3 3 3 0 DASH complex subunit Dad2 Use1 PF09753.9 EJP68288.1 - 0.003 17.3 0.5 0.0052 16.5 0.2 1.5 1 1 1 2 2 2 1 Membrane fusion protein Use1 Pox_A_type_inc PF04508.12 EJP68288.1 - 0.0079 16.0 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Not3 PF04065.15 EJP68288.1 - 0.023 14.1 2.4 0.062 12.7 0.0 1.9 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component PFL-like PF02901.15 EJP68288.1 - 0.052 12.2 0.2 0.063 11.9 0.2 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase-like BBP1_C PF15272.6 EJP68288.1 - 0.065 13.1 3.6 0.11 12.4 3.6 1.4 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Epimerase PF01370.21 EJP68289.1 - 7.8e-23 81.2 0.0 1.5e-22 80.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EJP68289.1 - 4e-18 65.4 0.0 5.1e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EJP68289.1 - 1.1e-13 51.3 0.0 2.5e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EJP68289.1 - 9.4e-13 47.9 0.0 2.1e-12 46.8 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EJP68289.1 - 2e-10 40.9 0.2 9.9e-10 38.6 0.2 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EJP68289.1 - 4e-08 33.1 0.0 1.2e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EJP68289.1 - 0.014 14.5 0.1 0.054 12.6 0.1 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 EJP68289.1 - 0.019 14.4 0.2 0.05 13.1 0.2 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Mur_ligase PF01225.25 EJP68289.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, catalytic domain KR PF08659.10 EJP68289.1 - 0.15 11.9 0.2 2.7 7.9 0.2 2.5 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EJP68289.1 - 0.2 10.7 0.0 0.43 9.7 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Phosducin PF02114.16 EJP68290.1 - 5.1e-12 45.3 0.1 7.1e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EJP68290.1 - 0.039 13.9 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DUF3350 PF11830.8 EJP68290.1 - 0.087 13.1 0.1 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) Ribosomal_S27e PF01667.17 EJP68291.1 - 1.7e-27 94.9 7.5 2.7e-27 94.2 7.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 HORMA PF02301.18 EJP68294.1 - 4.4e-11 42.8 0.0 6.2e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Lyase_1 PF00206.20 EJP68295.1 - 4.9e-41 141.1 0.0 9.6e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EJP68295.1 - 1.3e-14 54.7 0.0 3.3e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal ADSL_C PF10397.9 EJP68295.1 - 0.021 15.4 0.0 0.069 13.7 0.0 1.9 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus Aldedh PF00171.22 EJP68295.1 - 0.044 12.3 0.0 0.13 10.8 0.0 1.6 2 0 0 2 2 2 0 Aldehyde dehydrogenase family Nckap1 PF09735.9 EJP68297.1 - 0.0025 15.9 0.0 0.0027 15.8 0.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein VEGFR-2_TMD PF17988.1 EJP68297.1 - 0.023 14.1 0.9 0.038 13.4 0.9 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain RasGEF PF00617.19 EJP68298.1 - 4.5e-47 160.5 0.3 8.9e-47 159.6 0.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EJP68298.1 - 1e-12 48.2 1.7 1e-12 48.2 0.3 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif ABC_tran PF00005.27 EJP68298.1 - 0.0087 16.6 0.0 0.027 15.0 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EJP68298.1 - 0.026 14.8 0.9 2.4 8.4 0.0 3.8 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.23 EJP68298.1 - 0.06 13.4 0.4 0.17 11.9 0.4 1.8 1 0 0 1 1 1 0 Dynamin family AAA_33 PF13671.6 EJP68298.1 - 0.071 13.3 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EJP68298.1 - 0.092 12.3 0.0 0.58 9.7 0.0 2.3 1 1 0 1 1 1 0 Ras family AAA_24 PF13479.6 EJP68298.1 - 0.22 11.2 1.3 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain zf-HIT PF04438.16 EJP68300.1 - 6.7e-10 38.7 13.2 9.8e-10 38.1 13.2 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EJP68300.1 - 4.5e-05 23.5 7.4 7.8e-05 22.7 7.4 1.4 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 EJP68300.1 - 0.4 10.9 5.7 0.7 10.1 5.7 1.3 1 0 0 1 1 1 0 B-box zinc finger Nfu_N PF08712.11 EJP68301.1 - 1.8e-28 98.4 0.0 4.8e-28 97.0 0.0 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EJP68301.1 - 9.3e-26 89.8 0.0 1.6e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 EJP68301.1 - 0.042 13.9 0.5 0.18 11.9 0.5 2.0 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus PSP1 PF04468.12 EJP68302.1 - 5.5e-28 97.1 1.8 9.1e-28 96.4 1.8 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Ribosomal_L15e PF00827.17 EJP68304.1 - 3.1e-89 297.8 10.4 3.9e-89 297.5 10.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Aminotran_5 PF00266.19 EJP68305.1 - 8.1e-33 113.9 0.0 6.4e-32 110.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Phosphoesterase PF04185.14 EJP68306.1 - 9.6e-61 205.9 0.3 2.1e-60 204.8 0.3 1.6 1 1 0 1 1 1 1 Phosphoesterase family Trypsin PF00089.26 EJP68307.1 - 4e-40 138.0 0.1 5.1e-40 137.6 0.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EJP68307.1 - 1.4e-10 42.3 2.1 2.5e-10 41.5 2.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain p450 PF00067.22 EJP68308.1 - 3.8e-61 207.2 0.0 4.7e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sod_Cu PF00080.20 EJP68309.1 - 1.3e-47 161.6 6.7 1.5e-47 161.4 6.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Asp PF00026.23 EJP68310.1 - 6.1e-31 108.0 0.1 8e-20 71.5 0.2 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease SNase PF00565.17 EJP68311.1 - 6.7e-69 229.2 0.2 4.4e-19 68.9 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EJP68311.1 - 8.6e-24 83.9 0.0 1.6e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EJP68311.1 - 0.0027 17.0 0.5 0.006 15.9 0.0 1.7 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) YiaAB PF05360.14 EJP68312.1 - 0.24 11.7 4.7 0.77 10.0 0.1 3.1 3 0 0 3 3 3 0 yiaA/B two helix domain EI24 PF07264.11 EJP68313.1 - 9.3e-11 42.3 5.2 1.4e-10 41.7 5.2 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) CitG PF01874.16 EJP68313.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase TAL_FSA PF00923.19 EJP68314.1 - 1.1e-94 317.1 1.8 1.2e-94 316.9 1.8 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase TFA2_Winged_2 PF18121.1 EJP68314.1 - 0.041 13.6 0.0 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Cas_VVA1548 PF09652.10 EJP68314.1 - 0.11 12.7 0.2 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) Pkinase PF00069.25 EJP68315.1 - 1.7e-50 171.9 0.0 2.1e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP68315.1 - 2.6e-34 118.7 0.0 3.4e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP68315.1 - 9e-06 24.7 0.0 3.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EJP68315.1 - 0.00092 19.2 1.4 0.004 17.1 1.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP68315.1 - 0.018 14.3 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EJP68315.1 - 0.024 14.0 0.0 0.15 11.4 0.1 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family LELP1 PF15042.6 EJP68315.1 - 0.15 12.5 0.7 0.28 11.6 0.7 1.4 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Metallophos PF00149.28 EJP68316.1 - 2.9e-10 41.0 1.5 5.7e-10 40.0 1.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP68316.1 - 3.8e-07 30.4 0.2 3.8e-07 30.4 0.2 2.2 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Inj_translocase PF16928.5 EJP68316.1 - 0.0088 15.5 1.1 0.015 14.7 1.1 1.3 1 0 0 1 1 1 1 DNA/protein translocase of phage P22 injectosome GGDEF_2 PF17853.1 EJP68316.1 - 0.012 15.9 0.1 0.026 14.8 0.1 1.6 1 0 0 1 1 1 0 GGDEF-like domain DUF4834 PF16118.5 EJP68316.1 - 0.36 11.8 0.1 0.36 11.8 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Pet191_N PF10203.9 EJP68317.1 - 2.3e-27 95.1 6.0 2.9e-27 94.8 6.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.12 EJP68317.1 - 0.14 12.0 0.3 0.28 11.0 0.3 1.5 1 0 0 1 1 1 0 PAN-like domain NDUF_B7 PF05676.13 EJP68317.1 - 0.14 11.9 2.2 1.5 8.6 0.1 2.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 EJP68317.1 - 0.72 9.9 7.8 0.55 10.3 1.2 2.6 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Abhydrolase_1 PF00561.20 EJP68318.1 - 2.8e-25 89.4 0.3 3.8e-25 89.0 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EJP68318.1 - 2.3e-24 84.8 0.1 4.8e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EJP68318.1 - 1.9e-06 27.3 0.0 7.2e-05 22.2 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EJP68318.1 - 0.00064 19.4 0.1 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) zf-C3H1 PF10650.9 EJP68319.1 - 3.5e-05 23.4 1.8 6e-05 22.7 1.8 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Med21 PF11221.8 EJP68319.1 - 0.0041 17.4 4.5 0.0041 17.4 4.5 3.5 4 0 0 4 4 4 1 Subunit 21 of Mediator complex zf-CCCH PF00642.24 EJP68319.1 - 0.024 14.5 0.2 0.041 13.8 0.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SMAP PF15477.6 EJP68319.1 - 0.84 10.6 3.5 4.2 8.4 3.5 2.2 1 0 0 1 1 1 0 Small acidic protein family Myosin_head PF00063.21 EJP68320.1 - 5.3e-268 890.8 0.0 1.4e-267 889.4 0.0 1.8 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EJP68320.1 - 2.4e-13 49.7 0.7 6.2e-13 48.3 0.7 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 EJP68320.1 - 4.2e-13 48.1 275.8 4.7e-11 41.3 51.9 7.4 1 1 4 5 5 5 4 Myosin tail RsgA_GTPase PF03193.16 EJP68320.1 - 0.015 15.2 0.0 0.091 12.7 0.0 2.4 1 0 0 1 1 1 0 RsgA GTPase UDPG_MGDP_dh_N PF03721.14 EJP68320.1 - 0.099 12.2 2.7 0.3 10.6 2.7 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AAA_22 PF13401.6 EJP68320.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.8 5 0 0 5 5 5 0 AAA domain Peptidase_C12 PF01088.21 EJP68321.1 - 2.1e-55 187.7 0.0 2.6e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 zf-PARP PF00645.18 EJP68322.1 - 1.1e-21 77.4 3.9 1.1e-21 77.4 3.9 2.4 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PC4 PF02229.16 EJP68322.1 - 0.018 14.7 0.2 0.065 12.9 0.2 2.0 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) DTHCT PF08070.11 EJP68322.1 - 8.6 7.2 98.3 0.26 12.0 28.8 4.1 1 1 3 4 4 4 0 DTHCT (NUC029) region ALO PF04030.14 EJP68323.1 - 8.2e-92 307.7 0.7 1.2e-91 307.2 0.7 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EJP68323.1 - 1.1e-26 93.2 0.2 1.6e-26 92.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain SSF PF00474.17 EJP68324.1 - 7.4e-25 87.6 30.1 7.4e-25 87.6 30.1 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family S19 PF06756.11 EJP68324.1 - 0.1 12.5 0.0 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Chorion protein S19 C-terminal Internalin_N PF12354.8 EJP68324.1 - 2.7 8.1 7.9 0.92 9.6 0.2 4.1 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal Jacalin PF01419.17 EJP68325.1 - 0.0015 18.5 0.3 0.005 16.8 0.1 1.8 1 1 0 2 2 2 1 Jacalin-like lectin domain BPL_LplA_LipB PF03099.19 EJP68326.1 - 1.3e-06 28.4 0.0 3.9e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family SUR7 PF06687.12 EJP68327.1 - 1.1e-31 110.2 9.3 1.3e-31 109.9 9.3 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 EJP68327.1 - 0.0019 18.0 5.6 0.0019 18.0 5.6 1.6 2 0 0 2 2 2 1 Amastin surface glycoprotein DUF4064 PF13273.6 EJP68327.1 - 0.22 11.8 10.7 4.1 7.7 4.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Clc-like PF07062.12 EJP68327.1 - 0.62 9.5 8.6 0.042 13.3 3.6 1.5 2 0 0 2 2 2 0 Clc-like Wzy_C PF04932.15 EJP68327.1 - 2 8.0 8.7 2.2 7.9 4.8 2.3 2 1 0 2 2 2 0 O-Antigen ligase Pkinase PF00069.25 EJP68328.1 - 2.9e-52 177.6 0.0 4.6e-49 167.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP68328.1 - 1.1e-29 103.6 0.0 6.3e-29 101.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP68328.1 - 0.00072 19.0 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EJP68328.1 - 0.002 17.2 0.2 0.0034 16.5 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EJP68328.1 - 0.024 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EJP68328.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Mem_trans PF03547.18 EJP68329.1 - 1e-51 175.6 2.5 1.8e-31 109.0 0.0 2.0 2 0 0 2 2 2 2 Membrane transport protein Putative_PNPOx PF01243.20 EJP68330.1 - 1.4e-11 44.5 0.0 2.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EJP68330.1 - 0.036 14.1 0.0 0.09 12.8 0.0 1.6 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.14 EJP68330.1 - 0.04 12.4 0.0 0.045 12.2 0.0 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component CPSase_L_D2 PF02786.17 EJP68331.1 - 2.9e-74 249.1 0.0 4.6e-74 248.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EJP68331.1 - 4.4e-36 123.8 0.0 9.7e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EJP68331.1 - 3.4e-34 117.2 0.0 9.9e-34 115.7 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EJP68331.1 - 9.2e-17 60.6 0.5 4e-16 58.6 0.5 2.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EJP68331.1 - 1.8e-08 34.1 0.0 0.0079 16.0 0.0 3.0 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EJP68331.1 - 2.2e-07 30.6 0.0 5.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EJP68331.1 - 8.2e-07 28.8 0.0 2.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 EJP68331.1 - 1.7e-05 25.4 0.1 0.7 10.6 0.0 3.5 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 EJP68331.1 - 5e-05 23.4 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EJP68331.1 - 0.012 15.2 0.0 0.07 12.7 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 EJP68331.1 - 0.016 14.5 0.0 4 6.6 0.0 2.9 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion PI3_PI4_kinase PF00454.27 EJP68332.1 - 2.6e-46 158.5 0.0 6.8e-46 157.1 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EJP68332.1 - 6.7e-34 117.6 2.4 6.7e-34 117.6 2.4 2.3 2 0 0 2 2 2 1 FAT domain UME PF08064.13 EJP68332.1 - 2.1e-31 107.8 1.5 1e-30 105.6 0.1 3.1 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 EJP68332.1 - 9.4e-17 60.5 0.3 3.1e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 FATC domain Init_tRNA_PT PF04179.12 EJP68332.1 - 0.54 10.6 2.3 8.8 6.7 0.0 4.1 4 0 0 4 4 4 0 Rit1 DUSP-like domain TPR_19 PF14559.6 EJP68332.1 - 0.62 10.6 5.6 0.34 11.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat V-SNARE PF05008.15 EJP68332.1 - 0.84 10.1 3.4 1.6 9.2 2.0 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus p450 PF00067.22 EJP68333.1 - 8.3e-54 183.0 0.0 1.1e-53 182.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lyase_1 PF00206.20 EJP68334.1 - 5.7e-110 367.6 0.0 8.4e-110 367.0 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EJP68334.1 - 8.4e-21 74.2 0.1 1.9e-20 73.0 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus EAF PF09816.9 EJP68335.1 - 2.7e-23 82.3 0.0 2.7e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Cwf_Cwc_15 PF04889.12 EJP68335.1 - 0.0055 16.5 3.7 0.0055 16.5 3.7 2.5 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein ORC6 PF05460.13 EJP68335.1 - 2.6 7.2 11.0 4.4 6.5 10.9 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ATPgrasp_ST PF14397.6 EJP68336.1 - 0.051 12.8 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp TauD PF02668.16 EJP68337.1 - 8.5e-14 52.0 1.4 2e-13 50.8 1.4 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4128 PF13554.6 EJP68337.1 - 0.031 14.4 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function CsiD PF08943.10 EJP68337.1 - 0.044 12.9 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 CsiD GFA PF04828.14 EJP68339.1 - 2.7e-10 40.5 1.9 3.6e-10 40.1 1.9 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 EJP68339.1 - 1.8 8.3 0.0 1.8 8.3 0.0 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain POP1 PF06978.11 EJP68340.1 - 1.8e-74 250.2 13.8 1.8e-74 250.2 13.8 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EJP68340.1 - 9.1e-28 96.4 0.0 2e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.11 EJP68340.1 - 0.045 13.7 0.2 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain AA_permease_2 PF13520.6 EJP68341.1 - 7.4e-59 199.7 46.0 1e-58 199.2 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP68341.1 - 3.8e-21 75.2 36.6 5.3e-21 74.8 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 EJP68341.1 - 0.0053 16.7 0.0 0.0053 16.7 0.0 3.2 4 1 0 4 4 4 1 LPXTG cell wall anchor motif Aldedh PF00171.22 EJP68342.1 - 3.4e-162 540.2 0.1 3.8e-162 540.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aminotran_3 PF00202.21 EJP68343.1 - 3.9e-117 391.3 0.0 4.5e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.18 EJP68344.1 - 8.3e-19 67.6 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP68344.1 - 1.5e-06 28.2 9.8 3e-06 27.3 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NT-C2 PF10358.9 EJP68345.1 - 2.2e-26 92.3 0.6 8.7e-25 87.1 0.6 2.2 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins HSP70 PF00012.20 EJP68346.1 - 2.2e-79 267.2 4.8 2.8e-79 266.9 4.8 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJP68346.1 - 3.5e-09 35.9 0.1 5.9e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 EJP68346.1 - 0.001 18.8 1.0 0.0077 15.9 0.2 2.4 2 1 1 3 3 3 2 Periplasmic binding protein RXT2_N PF08595.11 EJP68346.1 - 0.11 12.5 0.2 0.36 10.8 0.2 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal Rrp40_N PF18311.1 EJP68347.1 - 9.4e-19 67.1 0.8 2.1e-17 62.8 0.5 2.4 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 EJP68347.1 - 1.9e-15 56.9 0.1 4.1e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 KH domain CarboxypepD_reg PF13620.6 EJP68347.1 - 0.071 13.4 0.5 0.95 9.8 0.1 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain zf-C2H2 PF00096.26 EJP68348.1 - 8.9e-09 35.3 21.7 0.0075 16.7 2.4 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP68348.1 - 0.0014 19.3 18.8 0.2 12.6 1.4 4.3 3 1 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 EJP68348.1 - 0.0022 18.6 8.4 0.0059 17.2 0.8 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EJP68348.1 - 0.01 16.0 2.8 0.089 12.9 0.4 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger Sina PF03145.16 EJP68348.1 - 0.37 10.7 11.9 1 9.3 11.8 1.7 1 1 0 1 1 1 0 Seven in absentia protein family zf-C2H2_8 PF15909.5 EJP68348.1 - 0.55 10.6 4.4 1.4 9.2 1.7 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon GREB1 PF15782.5 EJP68351.1 - 9 3.3 8.7 10 3.1 8.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SEN1_N PF12726.7 EJP68352.1 - 2.5e-196 654.3 7.8 3.4e-196 653.8 7.8 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EJP68352.1 - 4.2e-73 246.3 1.4 4.2e-73 246.3 1.4 3.1 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 EJP68352.1 - 4.4e-61 206.0 0.0 9.3e-61 204.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP68352.1 - 1.7e-08 34.9 0.1 6.9e-08 33.0 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP68352.1 - 2.8e-07 30.4 0.4 0.00098 18.9 0.2 2.8 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EJP68352.1 - 0.0017 18.1 0.2 0.38 10.5 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EJP68352.1 - 0.011 16.0 1.1 0.12 12.6 0.0 3.0 2 1 1 3 3 3 0 AAA domain Phage_tail_X PF05489.12 EJP68352.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Phage Tail Protein X ResIII PF04851.15 EJP68352.1 - 0.1 12.6 0.1 0.62 10.0 0.1 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1857 PF08982.11 EJP68353.1 - 8.9e-31 106.7 0.0 1e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Polyketide_cyc2 PF10604.9 EJP68353.1 - 0.0012 19.2 0.0 0.0018 18.6 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ADH_N PF08240.12 EJP68355.1 - 2e-23 82.4 0.3 3.5e-23 81.6 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP68355.1 - 2.6e-12 46.9 0.1 4.6e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EJP68355.1 - 0.00037 19.8 0.1 0.00059 19.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EJP68355.1 - 0.00087 18.7 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IBR PF01485.21 EJP68356.1 - 5.6e-10 39.3 33.7 1.3e-05 25.3 8.2 3.5 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain fn3_2 PF16893.5 EJP68358.1 - 5.2e-38 129.1 0.0 8.4e-38 128.4 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EJP68358.1 - 3.2e-23 81.4 0.8 5.1e-23 80.8 0.8 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EJP68358.1 - 4.5e-12 45.7 0.0 8.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EJP68358.1 - 7.5e-10 39.0 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EJP68358.1 - 3.2e-06 27.5 0.0 6.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 EJP68358.1 - 0.00064 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 EJP68358.1 - 0.0048 17.1 2.1 0.0069 16.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) Pyrid_oxidase_2 PF13883.6 EJP68359.1 - 4.2e-40 137.5 0.0 5.8e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Csa1 PF06023.12 EJP68359.1 - 0.095 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 DNA_methylase PF00145.17 EJP68360.1 - 4.1e-20 72.4 0.1 1.4e-09 37.8 0.0 3.1 2 1 1 3 3 3 3 C-5 cytosine-specific DNA methylase bZIP_1 PF00170.21 EJP68361.1 - 0.15 12.2 4.9 0.28 11.3 4.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor DJ-1_PfpI PF01965.24 EJP68362.1 - 2.6e-14 53.4 0.0 3.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ABC_tran PF00005.27 EJP68364.1 - 1.4e-52 177.9 0.0 8.8e-27 94.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EJP68364.1 - 1.1e-22 81.3 1.0 4.2e-06 26.8 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EJP68364.1 - 2.5e-20 72.9 35.2 1.3e-12 47.5 14.3 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 EJP68364.1 - 1.5e-13 50.7 0.1 0.00027 20.4 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP68364.1 - 1.7e-07 30.8 0.7 0.0087 15.8 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EJP68364.1 - 4.4e-07 30.6 0.4 0.022 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EJP68364.1 - 1e-06 28.8 0.0 0.3 10.8 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EJP68364.1 - 2.3e-06 27.6 0.0 0.00073 19.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EJP68364.1 - 2.3e-06 28.1 0.0 0.0069 16.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EJP68364.1 - 9.7e-06 25.4 0.3 0.18 11.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EJP68364.1 - 2.9e-05 24.3 0.0 0.42 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EJP68364.1 - 8.8e-05 22.9 0.2 0.093 13.2 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EJP68364.1 - 0.00013 21.1 0.0 0.36 9.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Rad17 PF03215.15 EJP68364.1 - 0.00018 21.5 0.0 0.09 12.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain SRP54 PF00448.22 EJP68364.1 - 0.00086 19.0 0.2 0.4 10.3 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 EJP68364.1 - 0.0011 19.0 2.8 0.67 9.9 0.2 3.0 3 0 0 3 3 3 2 NACHT domain AAA_33 PF13671.6 EJP68364.1 - 0.0013 18.9 0.1 0.99 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EJP68364.1 - 0.002 17.4 0.6 0.74 9.0 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 EJP68364.1 - 0.0028 17.7 0.2 0.38 10.9 0.1 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EJP68364.1 - 0.0029 17.3 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EJP68364.1 - 0.0047 16.6 0.0 2.2 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EJP68364.1 - 0.0065 16.1 0.0 0.78 9.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 EJP68364.1 - 0.0075 15.9 0.4 1.8 8.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EJP68364.1 - 0.0089 15.2 1.2 1.7 7.8 0.5 3.1 2 1 0 2 2 2 1 NB-ARC domain TsaE PF02367.17 EJP68364.1 - 0.011 15.8 0.4 4.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EJP68364.1 - 0.011 15.7 0.2 7.3 6.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EJP68364.1 - 0.011 15.1 0.1 20 4.5 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EJP68364.1 - 0.013 15.8 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EJP68364.1 - 0.014 15.6 0.1 6.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EJP68364.1 - 0.023 14.7 0.0 8.7 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EJP68364.1 - 0.03 14.7 0.3 3 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 EJP68364.1 - 0.069 12.0 0.0 0.49 9.2 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_18 PF13238.6 EJP68364.1 - 0.084 13.4 0.3 10 6.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EJP68364.1 - 0.11 12.4 0.4 16 5.3 0.0 2.5 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.17 EJP68364.1 - 0.18 11.5 1.4 15 5.3 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Med12 PF09497.10 EJP68365.1 - 7.5e-28 96.6 0.3 1.8e-27 95.4 0.3 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 RhoGAP PF00620.27 EJP68366.1 - 2.4e-47 160.5 0.1 6.5e-47 159.2 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EJP68366.1 - 1.3e-15 57.4 0.3 1.3e-15 57.4 0.3 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BBP1_C PF15272.6 EJP68366.1 - 0.024 14.5 5.1 0.061 13.1 5.0 1.7 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF5321 PF17254.2 EJP68366.1 - 0.22 10.9 1.5 0.45 9.9 1.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5321) GIDA_assoc PF13932.6 EJP68366.1 - 0.9 9.7 6.6 0.73 10.0 4.9 1.7 1 1 0 1 1 1 0 GidA associated domain Ribosomal_S28e PF01200.18 EJP68367.1 - 1.3e-23 82.8 12.3 7.7e-17 61.0 1.6 2.6 2 1 1 3 3 3 3 Ribosomal protein S28e Pkinase PF00069.25 EJP68368.1 - 7.7e-60 202.5 0.0 7.4e-59 199.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP68368.1 - 9.2e-29 100.5 0.2 3.4e-19 69.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EJP68368.1 - 0.00068 20.3 2.0 0.0026 18.4 1.0 2.5 2 1 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.23 EJP68368.1 - 0.013 15.4 0.2 0.74 9.7 0.0 3.2 2 2 0 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP68368.1 - 0.032 13.5 0.3 0.11 11.7 0.0 2.0 3 0 0 3 3 3 0 Kinase-like Haspin_kinase PF12330.8 EJP68368.1 - 0.043 12.7 0.0 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EJP68368.1 - 0.048 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GATA PF00320.27 EJP68369.1 - 1.6e-16 59.6 2.3 3.1e-16 58.7 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EJP68369.1 - 3.2e-11 42.9 0.8 5.9e-11 42.0 0.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Wbp11 PF09429.10 EJP68370.1 - 1.5e-23 83.0 11.8 1.5e-23 83.0 11.8 2.8 3 1 0 3 3 3 1 WW domain binding protein 11 PAG PF15347.6 EJP68370.1 - 0.0037 16.3 1.1 0.006 15.6 1.1 1.3 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched Lipoprotein_7 PF01540.16 EJP68370.1 - 0.03 13.6 2.3 0.049 12.9 2.3 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein Tad PF13400.6 EJP68370.1 - 0.41 11.0 1.1 0.94 9.8 1.1 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like MFS_1 PF07690.16 EJP68371.1 - 3.6e-38 131.4 71.3 9.3e-34 116.9 48.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68371.1 - 5.2e-06 25.6 39.3 1.4e-05 24.2 10.6 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter Peptidase_M43 PF05572.13 EJP68372.1 - 1.4e-17 64.0 0.0 2.3e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EJP68372.1 - 0.00014 22.1 0.1 0.00057 20.1 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EJP68372.1 - 0.0023 18.4 0.1 0.0076 16.8 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EJP68372.1 - 0.003 17.5 0.1 0.0052 16.7 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EJP68372.1 - 0.078 12.6 0.2 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EJP68372.1 - 0.089 12.6 0.2 0.15 11.9 0.2 1.5 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 EJP68372.1 - 0.1 11.5 0.2 0.17 10.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 DFP PF04127.15 EJP68373.1 - 1.8e-13 50.7 0.0 8.4e-06 25.7 0.0 3.1 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein HAD PF12710.7 EJP68373.1 - 0.038 14.4 0.0 0.095 13.1 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 EJP68374.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EJP68374.1 - 0.1 12.5 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 F-box domain PRANC PF09372.10 EJP68374.1 - 0.12 12.8 0.0 0.54 10.6 0.0 2.0 2 0 0 2 2 2 0 PRANC domain Acatn PF13000.7 EJP68375.1 - 1e-155 519.4 19.8 7.9e-82 275.5 11.5 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.10 EJP68376.1 - 5.3e-64 216.1 0.0 1.7e-63 214.4 0.0 1.7 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Uds1 PF15456.6 EJP68376.1 - 0.00079 19.6 0.9 0.00079 19.6 0.9 1.8 2 0 0 2 2 2 1 Up-regulated During Septation Ogr_Delta PF04606.12 EJP68377.1 - 0.16 12.0 4.2 0.28 11.2 4.2 1.4 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Yae1_N PF09811.9 EJP68378.1 - 2.3e-11 43.2 0.4 4.3e-11 42.3 0.4 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal NQRA PF05896.11 EJP68378.1 - 0.08 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Glyco_hydro_18 PF00704.28 EJP68379.1 - 2.9e-25 89.7 1.7 5.4e-25 88.8 1.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 EJP68379.1 - 1.3e-10 41.0 12.4 1.3e-10 41.0 12.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain p450 PF00067.22 EJP68380.1 - 4.9e-50 170.6 0.0 7.2e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EJP68382.1 - 9.7e-47 159.8 0.0 1.7e-46 158.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 tRNA-synt_His PF13393.6 EJP68382.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase MFS_1 PF07690.16 EJP68383.1 - 2.2e-39 135.4 32.3 5.4e-37 127.5 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68383.1 - 4e-12 45.8 4.3 4e-12 45.8 4.3 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP68383.1 - 0.00069 18.2 0.9 0.001 17.6 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AAA_18 PF13238.6 EJP68384.1 - 1.1e-05 26.0 0.0 0.00021 21.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EJP68384.1 - 0.00026 21.2 0.1 0.00061 20.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain CPT PF07931.12 EJP68384.1 - 0.014 15.3 0.0 0.95 9.3 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 EJP68384.1 - 0.085 12.2 0.1 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 EJP68384.1 - 0.093 12.6 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase MmgE_PrpD PF03972.14 EJP68385.1 - 3.1e-147 490.7 0.0 3.9e-147 490.3 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family GTP_EFTU PF00009.27 EJP68386.1 - 2.6e-55 187.0 0.0 3.8e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EJP68386.1 - 9.7e-42 141.8 0.0 2.2e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EJP68386.1 - 1.2e-14 54.5 3.5 1.3e-14 54.3 1.6 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EJP68386.1 - 0.00024 21.2 0.1 0.0061 16.6 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EJP68386.1 - 0.0094 15.8 0.8 0.031 14.2 0.8 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SLS PF14611.6 EJP68387.1 - 2e-36 125.9 0.6 2e-36 125.9 0.6 2.4 3 0 0 3 3 3 1 Mitochondrial inner-membrane-bound regulator MAGE PF01454.19 EJP68388.1 - 2.2e-65 220.4 0.0 2.8e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 MAGE family SF3b10 PF07189.11 EJP68389.1 - 1.3e-36 124.6 0.0 1.6e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) zf-MYND PF01753.18 EJP68390.1 - 1.4e-06 28.3 18.3 7.5e-05 22.7 0.2 3.5 2 1 1 3 3 3 2 MYND finger zf-C6H2 PF15801.5 EJP68390.1 - 0.0079 16.5 18.3 0.094 13.0 2.8 3.6 3 1 0 3 3 3 2 zf-MYND-like zinc finger, mRNA-binding VHS PF00790.19 EJP68390.1 - 0.052 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 VHS domain Ecl1 PF12855.7 EJP68390.1 - 0.2 12.8 9.5 3.4 8.8 1.2 3.2 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins FUSC PF04632.12 EJP68390.1 - 0.94 7.9 8.0 0.075 11.6 1.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family WD40 PF00400.32 EJP68391.1 - 3.2e-37 125.9 14.1 1.8e-06 28.6 0.2 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP68391.1 - 8.8e-06 25.9 0.1 1.2 9.5 0.0 4.2 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP68391.1 - 1.9e-05 23.5 2.2 0.00089 18.0 0.1 3.3 2 2 1 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EJP68391.1 - 0.00075 18.4 0.0 0.0034 16.2 0.0 2.1 2 1 0 2 2 2 1 Nup133 N terminal like DUF5046 PF16465.5 EJP68391.1 - 0.12 11.8 0.0 6.3 6.2 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) Methyltransf_12 PF08242.12 EJP68392.1 - 7.3e-07 29.9 0.0 4.6e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP68392.1 - 5.8e-06 26.9 0.0 1.3e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP68392.1 - 0.0006 19.2 0.0 0.0018 17.6 0.0 1.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EJP68392.1 - 0.0045 16.6 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EJP68392.1 - 0.0075 16.1 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain THB PF18362.1 EJP68392.1 - 0.11 12.1 1.1 21 4.8 0.1 3.0 3 0 0 3 3 3 0 Tri-helix bundle domain Zn_clus PF00172.18 EJP68393.1 - 1.9e-08 34.3 8.5 3.4e-08 33.5 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP68393.1 - 2.5e-06 26.7 0.0 4.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_red PF03358.15 EJP68394.1 - 9.3e-29 100.2 0.0 1.3e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EJP68394.1 - 2.5e-08 33.9 0.1 4.7e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold DnaJ PF00226.31 EJP68395.1 - 5.1e-07 29.7 0.1 1.2e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Aa_trans PF01490.18 EJP68396.1 - 1.6e-40 139.1 34.2 1.8e-40 138.9 34.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PIG-P PF08510.12 EJP68396.1 - 0.084 12.8 0.4 0.084 12.8 0.4 2.5 2 1 0 2 2 2 0 PIG-P AIRC PF00731.20 EJP68397.1 - 7.9e-58 194.2 0.2 2.6e-57 192.5 0.3 1.9 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 EJP68397.1 - 2.7e-43 147.5 0.0 5.3e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EJP68397.1 - 4.1e-15 55.2 0.0 7.9e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EJP68397.1 - 0.00011 21.8 0.0 0.0003 20.3 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 EJP68397.1 - 0.00083 18.9 0.0 0.0024 17.4 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Amidase PF01425.21 EJP68398.1 - 8.3e-78 262.3 0.7 2e-77 261.1 0.7 1.5 1 1 0 1 1 1 1 Amidase Glyco_hydro_3_C PF01915.22 EJP68401.1 - 1.5e-41 142.6 0.0 2.2e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EJP68401.1 - 2.7e-37 128.9 0.0 5.2e-37 127.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EJP68401.1 - 6.6e-22 77.4 0.2 1.2e-21 76.6 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain ARGLU PF15346.6 EJP68402.1 - 0.0035 17.2 6.9 0.0052 16.7 6.9 1.2 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 Spt20 PF12090.8 EJP68402.1 - 2.4 7.7 15.2 0.057 13.0 8.6 1.6 2 0 0 2 2 2 0 Spt20 family Androgen_recep PF02166.16 EJP68402.1 - 2.5 6.9 18.1 0.038 12.8 3.0 2.4 2 0 0 2 2 2 0 Androgen receptor TFIIA PF03153.13 EJP68402.1 - 4.2 7.3 15.5 0.13 12.3 7.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 EJP68402.1 - 4.8 6.0 16.8 0.043 12.8 9.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RRM_1 PF00076.22 EJP68403.1 - 9.5e-13 47.8 0.0 1.1e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 EJP68404.1 - 3.8e-51 172.9 0.0 4.6e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP68404.1 - 2.8e-18 66.3 0.0 3.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP68404.1 - 6.5e-09 35.5 0.0 7.7e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EJP68404.1 - 2.7e-05 24.1 0.0 0.058 13.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EJP68404.1 - 3.1e-05 23.6 0.1 0.00033 20.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EJP68404.1 - 0.00037 20.6 0.0 0.00053 20.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EJP68404.1 - 0.04 13.1 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 EJP68404.1 - 0.075 13.4 0.1 0.11 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Caskin-tail PF16632.5 EJP68405.1 - 0.082 13.3 0.8 0.42 11.1 0.0 2.4 2 0 0 2 2 2 0 C-terminal region of Caskin Ank_2 PF12796.7 EJP68406.1 - 1.9e-16 60.4 0.0 1.9e-09 38.0 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) AAA_16 PF13191.6 EJP68406.1 - 5.3e-10 39.9 0.7 1.8e-09 38.2 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain Ank_4 PF13637.6 EJP68406.1 - 5.2e-09 36.5 0.1 1.7e-07 31.6 0.0 3.5 3 1 1 4 4 3 1 Ankyrin repeats (many copies) NACHT PF05729.12 EJP68406.1 - 8.1e-09 35.6 1.2 3.7e-08 33.4 0.0 2.5 3 0 0 3 3 3 1 NACHT domain Ank_5 PF13857.6 EJP68406.1 - 1.3e-06 28.5 0.7 4.6e-06 26.8 0.0 2.3 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EJP68406.1 - 1.5e-06 28.4 0.0 0.00019 21.8 0.1 3.4 4 0 0 4 4 2 1 Ankyrin repeat Ank_3 PF13606.6 EJP68406.1 - 5.3e-06 26.4 0.7 0.0031 17.9 0.0 4.5 5 0 0 5 5 3 1 Ankyrin repeat AAA_22 PF13401.6 EJP68406.1 - 0.00022 21.5 0.0 0.0015 18.8 0.0 2.5 2 1 0 2 2 1 1 AAA domain KAP_NTPase PF07693.14 EJP68406.1 - 0.1 11.8 0.0 9.3 5.4 0.2 2.3 1 1 1 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 EJP68406.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EJP68406.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Adaptin_N PF01602.20 EJP68408.1 - 3.6e-112 375.6 2.1 4.7e-112 375.2 2.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EJP68408.1 - 5.6e-55 185.6 4.0 1.4e-54 184.3 4.0 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EJP68408.1 - 1.3e-35 122.0 0.2 3.7e-35 120.5 0.2 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EJP68408.1 - 3.8e-17 62.4 1.9 1.1e-11 45.0 0.1 5.1 3 1 2 5 5 5 2 HEAT repeats Cnd1 PF12717.7 EJP68408.1 - 2e-06 28.0 14.2 0.0075 16.3 0.1 5.3 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EJP68408.1 - 0.0044 17.1 4.6 1.2 9.6 0.1 5.1 4 0 0 4 4 4 1 HEAT repeat HEAT_PBS PF03130.16 EJP68408.1 - 0.006 17.1 0.6 15 6.7 0.1 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Alpha_adaptin_C PF02296.16 EJP68408.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain RTP1_C1 PF10363.9 EJP68408.1 - 0.13 12.4 0.8 3.8 7.7 0.0 3.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 ATP12 PF07542.11 EJP68409.1 - 1.5e-42 144.8 0.8 6.1e-42 142.8 0.1 2.0 2 0 0 2 2 2 1 ATP12 chaperone protein K_oxygenase PF13434.6 EJP68410.1 - 4.2e-12 45.9 0.0 5.1e-09 35.7 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EJP68410.1 - 1e-11 44.0 0.3 3.5e-11 42.2 0.2 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EJP68410.1 - 1.2e-07 31.9 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EJP68410.1 - 0.00054 19.3 0.0 0.084 12.1 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP68410.1 - 0.0049 16.1 0.0 0.92 8.7 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP68410.1 - 0.0097 15.9 0.1 0.1 12.6 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EJP68410.1 - 0.19 11.8 0.0 0.56 10.3 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 EJP68412.1 - 9.3e-33 113.3 0.0 1.3e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP68412.1 - 1.9e-20 73.5 0.0 2.7e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP68412.1 - 2.2e-09 37.5 0.0 6.8e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP68412.1 - 4.5e-05 23.0 0.0 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EJP68412.1 - 0.00084 18.8 0.0 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 EJP68412.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_3 PF07859.13 EJP68413.1 - 1.4e-20 74.0 0.0 2e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP68413.1 - 5.9e-13 48.4 0.0 8.4e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF1378 PF07125.11 EJP68413.1 - 0.3 11.3 0.7 0.63 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) DAO PF01266.24 EJP68414.1 - 2.4e-32 112.9 0.2 1.1e-31 110.8 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HTH_Tnp_Tc5 PF03221.16 EJP68414.1 - 3.5e-05 23.7 0.0 7.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain 3HCDH_N PF02737.18 EJP68414.1 - 0.00042 20.2 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EJP68414.1 - 0.00089 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EJP68414.1 - 0.015 15.7 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 EJP68414.1 - 0.017 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EJP68414.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EJP68414.1 - 0.021 15.4 0.6 0.05 14.2 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HTH_23 PF13384.6 EJP68414.1 - 0.022 14.6 0.0 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain ApbA PF02558.16 EJP68414.1 - 0.043 13.5 0.4 0.087 12.5 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HTH_psq PF05225.16 EJP68414.1 - 0.049 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_28 PF13518.6 EJP68414.1 - 0.051 13.7 0.1 1.9 8.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_8 PF02954.19 EJP68414.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Pyr_redox_3 PF13738.6 EJP68414.1 - 0.18 11.0 0.1 0.38 10.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Asp PF00026.23 EJP68415.1 - 2.1e-57 194.9 0.0 2.9e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP68415.1 - 1.1e-11 45.3 4.3 5.2e-11 43.1 0.5 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP68415.1 - 0.00015 22.3 0.0 1.1 9.9 0.0 3.6 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EJP68415.1 - 0.031 14.1 0.0 2.7 7.8 0.0 2.9 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal AMP-binding PF00501.28 EJP68416.1 - 1.3e-76 258.0 0.0 1.6e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP68416.1 - 2.4e-13 50.8 0.7 7.5e-13 49.3 0.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CFEM PF05730.11 EJP68417.1 - 8.4e-06 25.8 4.7 8.4e-06 25.8 4.7 2.2 3 0 0 3 3 3 1 CFEM domain GETHR PF05671.11 EJP68417.1 - 0.71 9.3 14.8 0.018 14.4 5.9 2.8 2 0 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) bVLRF1 PF18826.1 EJP68419.1 - 1.7e-63 213.0 0.1 4e-63 211.8 0.1 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EJP68419.1 - 1.3e-06 28.5 0.0 3.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) CDC45 PF02724.14 EJP68419.1 - 5.7 5.1 9.8 0.54 8.5 0.1 2.2 2 0 0 2 2 2 0 CDC45-like protein FAD_binding_7 PF03441.14 EJP68422.1 - 1.1e-45 155.6 1.1 1.8e-45 154.9 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EJP68422.1 - 6.8e-19 68.5 0.0 1.5e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase SH3_1 PF00018.28 EJP68423.1 - 3.5e-13 48.9 0.1 5.6e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP68423.1 - 3.5e-10 39.6 0.1 5.1e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJP68423.1 - 3.7e-09 36.1 0.0 5.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 EJP68424.1 - 9.9e-25 87.2 17.4 9.9e-25 87.2 17.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68424.1 - 6.1e-08 32.0 1.6 6.1e-08 32.0 1.6 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Ycf9 PF01737.17 EJP68424.1 - 4.4 7.2 11.3 0.083 12.8 0.5 3.3 3 0 0 3 3 3 0 YCF9 Reprolysin_3 PF13582.6 EJP68425.1 - 0.011 16.3 0.6 0.044 14.3 0.1 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M90 PF06167.12 EJP68425.1 - 0.19 11.3 0.9 0.44 10.1 0.9 1.4 1 1 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 p450 PF00067.22 EJP68426.1 - 1.6e-59 201.8 0.0 2.1e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 EJP68427.1 - 3.6e-57 194.2 26.8 4.4e-57 193.9 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP68427.1 - 1.7e-23 83.1 42.3 1.4e-22 80.1 37.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease_2 PF13520.6 EJP68428.1 - 4.4e-54 183.9 47.1 5.3e-54 183.7 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP68428.1 - 5.1e-30 104.5 43.0 7.2e-30 104.0 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease B12D PF06522.11 EJP68428.1 - 2.4 8.0 3.7 3.6 7.4 0.0 2.9 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit WD40 PF00400.32 EJP68429.1 - 4.2e-16 59.0 11.2 3.9e-07 30.7 0.3 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EJP68429.1 - 1.2e-13 51.1 0.7 9.8e-13 48.2 0.0 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EJP68429.1 - 1.2e-08 35.1 0.5 0.0074 16.6 0.1 3.4 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4350 PF14258.6 EJP68430.1 - 0.00035 20.9 0.1 0.00089 19.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) Cytidylate_kin2 PF13189.6 EJP68430.1 - 0.039 14.1 0.0 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family Robl_LC7 PF03259.17 EJP68431.1 - 6.5e-10 38.7 0.2 9.6e-10 38.1 0.2 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain Glyco_hydro2_C5 PF18565.1 EJP68431.1 - 0.015 15.1 0.4 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 RTX_C PF08339.10 EJP68431.1 - 0.02 14.9 0.1 0.033 14.2 0.1 1.5 2 0 0 2 2 2 0 RTX C-terminal domain LAMTOR5 PF16672.5 EJP68431.1 - 0.073 13.0 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 APH PF01636.23 EJP68432.1 - 2.5e-11 44.0 0.2 6e-11 42.7 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP68432.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase NACHT PF05729.12 EJP68433.1 - 4.9e-15 55.8 0.3 5.5e-14 52.4 0.0 2.9 3 0 0 3 3 2 1 NACHT domain HEAT_2 PF13646.6 EJP68433.1 - 1.3e-09 38.3 14.9 0.00018 21.8 1.0 5.2 4 2 2 6 6 6 4 HEAT repeats NB-ARC PF00931.22 EJP68433.1 - 4.8e-06 25.9 0.0 1.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain NLRC4_HD2 PF17776.1 EJP68433.1 - 0.00011 22.8 1.1 0.0004 20.9 0.1 2.5 2 0 0 2 2 2 1 NLRC4 helical domain HD2 AAA_22 PF13401.6 EJP68433.1 - 0.0015 18.8 0.1 0.011 16.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP68433.1 - 0.0077 16.6 0.4 0.06 13.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain DUF5136 PF17199.4 EJP68433.1 - 0.031 14.0 0.1 0.088 12.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) HEAT PF02985.22 EJP68433.1 - 0.034 14.4 1.2 1.2e+02 3.4 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat NTPase_1 PF03266.15 EJP68433.1 - 0.034 14.0 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 NTPase HEAT_EZ PF13513.6 EJP68433.1 - 0.045 14.3 6.4 11 6.7 0.0 5.5 5 1 1 6 6 6 0 HEAT-like repeat AAA_18 PF13238.6 EJP68433.1 - 0.076 13.6 0.0 0.24 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EJP68433.1 - 0.1 12.7 0.0 0.81 9.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EJP68433.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PgdA_N PF18627.1 EJP68433.1 - 0.21 11.2 0.7 15 5.1 0.2 2.5 2 0 0 2 2 2 0 Peptidoglycan GlcNAc deacetylase N-terminal domain DcpS_C PF11969.8 EJP68434.1 - 8.6e-16 58.4 2.4 2e-15 57.2 2.4 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EJP68434.1 - 4.7e-06 27.3 8.7 3.2e-05 24.6 8.7 2.0 1 1 0 1 1 1 1 HIT domain DUF4931 PF16285.5 EJP68434.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) Claudin_3 PF06653.11 EJP68435.1 - 0.00075 19.5 1.2 0.0013 18.7 1.2 1.3 1 0 0 1 1 1 1 Tight junction protein, Claudin-like SPC12 PF06645.13 EJP68435.1 - 3.1 8.0 4.6 1 9.5 0.6 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) LAX PF15681.5 EJP68435.1 - 5.4 5.7 4.6 2.4 6.9 0.7 2.0 2 0 0 2 2 2 0 Lymphocyte activation family X Amidase PF01425.21 EJP68436.1 - 4.6e-71 240.1 0.0 3.3e-70 237.3 0.0 1.9 1 1 0 1 1 1 1 Amidase eRF1_1 PF03463.15 EJP68437.1 - 1.5e-41 141.4 0.0 2.8e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EJP68437.1 - 3.9e-18 66.0 0.0 6.2e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EJP68437.1 - 1.9e-15 57.3 0.0 3.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 Peptidase_M61 PF05299.12 EJP68438.1 - 3.1e-32 111.5 0.0 5.4e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 M61 glycyl aminopeptidase Peptidase_M61_N PF17899.1 EJP68438.1 - 5.2e-21 75.4 0.0 8.5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M61 N-terminal domain PDZ_2 PF13180.6 EJP68438.1 - 0.00056 20.2 0.1 0.00093 19.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_M9 PF01752.17 EJP68438.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Collagenase WD40 PF00400.32 EJP68439.1 - 7.2e-23 80.5 7.2 4.8e-05 24.1 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP68439.1 - 0.00016 21.9 0.0 1.2 9.5 0.0 4.3 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP68439.1 - 0.074 12.0 0.0 0.43 9.5 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Thioredoxin PF00085.20 EJP68440.1 - 1.1e-19 70.3 0.0 1.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EJP68440.1 - 4.5e-06 26.2 0.2 5.2e-06 26.0 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EJP68440.1 - 4.5e-06 26.4 0.0 5.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EJP68440.1 - 0.025 15.0 0.2 0.2 12.1 0.2 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EJP68440.1 - 0.053 13.8 0.0 0.28 11.5 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like Prp19 PF08606.11 EJP68441.1 - 2.6e-32 110.6 2.6 6.1e-32 109.4 2.6 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EJP68441.1 - 7.3e-10 39.0 0.1 0.00056 20.2 0.0 4.6 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJP68441.1 - 9.6e-10 38.9 0.6 0.33 11.9 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat V_ATPase_I_N PF18670.1 EJP68441.1 - 0.0025 18.2 0.7 0.024 15.0 0.2 2.4 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain Coatomer_WDAD PF04053.14 EJP68441.1 - 0.0079 15.3 0.0 0.11 11.5 0.0 2.4 1 1 1 2 2 2 1 Coatomer WD associated region zf-Nse PF11789.8 EJP68441.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EJP68441.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 U-box domain VID27 PF08553.10 EJP68441.1 - 0.016 14.3 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain HPS3_N PF14761.6 EJP68441.1 - 0.033 13.7 0.0 0.18 11.3 0.0 2.0 1 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Lactonase PF10282.9 EJP68441.1 - 0.037 13.3 0.0 0.099 11.9 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller OHCU_decarbox PF09349.10 EJP68442.1 - 1.2e-44 152.6 0.1 1.3e-44 152.4 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Glyco_tran_WecB PF03808.13 EJP68442.1 - 0.076 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family 4HBT_3 PF13622.6 EJP68443.1 - 2.4e-18 67.3 5.2 4.8e-18 66.3 5.2 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily Glyco_hydro_16 PF00722.21 EJP68444.1 - 4.9e-38 130.4 0.0 1.3e-37 129.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BRO1 PF03097.18 EJP68445.1 - 6.7e-123 410.3 0.1 6.7e-123 410.3 0.1 1.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EJP68445.1 - 1.3e-81 274.1 6.1 1.3e-81 274.1 6.1 2.1 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF148 PF02520.17 EJP68445.1 - 0.0057 16.8 0.9 0.035 14.2 0.9 2.4 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF2621 PF11084.8 EJP68445.1 - 0.029 14.3 0.0 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) K-box PF01486.17 EJP68445.1 - 0.06 13.5 0.0 0.06 13.5 0.0 2.7 2 0 0 2 2 2 0 K-box region UPF0242 PF06785.11 EJP68445.1 - 2.6 8.1 14.8 3.5 7.7 4.3 3.7 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus SMBP PF16785.5 EJP68445.1 - 3.2 8.0 8.7 5.2 7.3 2.0 2.9 3 0 0 3 3 3 0 Small metal-binding protein LsmAD PF06741.13 EJP68445.1 - 3.9 8.1 5.5 3.4 8.3 2.7 2.4 2 0 0 2 2 2 0 LsmAD domain Band_7 PF01145.25 EJP68446.1 - 4.9e-16 59.3 0.0 4.9e-16 59.3 0.0 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Reprolysin_5 PF13688.6 EJP68447.1 - 1.2e-49 169.1 1.8 1.2e-49 169.1 1.8 3.1 2 1 2 4 4 4 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EJP68447.1 - 1.1e-40 139.5 0.4 2.2e-40 138.5 0.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EJP68447.1 - 3.6e-38 131.4 0.2 3.6e-38 131.4 0.2 3.0 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EJP68447.1 - 2.2e-16 60.4 29.9 2.2e-16 60.4 29.9 4.4 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EJP68447.1 - 7.2e-11 42.7 0.7 6.7e-10 39.6 0.0 2.8 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 EJP68447.1 - 4.7e-07 29.9 2.1 5.8e-06 26.4 2.1 2.6 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 EJP68447.1 - 0.0012 19.0 0.2 0.0023 18.2 0.2 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide OPT PF03169.15 EJP68449.1 - 6.9e-160 533.7 48.5 7.9e-160 533.5 48.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.14 EJP68449.1 - 0.012 15.6 1.1 0.16 12.1 0.0 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Esterase_phd PF10503.9 EJP68450.1 - 0.00045 19.8 0.3 0.00045 19.8 0.3 1.9 2 1 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EJP68450.1 - 0.068 12.6 1.4 0.44 10.0 1.3 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family Epimerase PF01370.21 EJP68451.1 - 6e-23 81.6 0.0 1.4e-22 80.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP68451.1 - 1.4e-21 77.3 0.1 3e-14 53.2 0.0 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EJP68451.1 - 6.7e-10 38.5 0.0 1.2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EJP68451.1 - 9.9e-10 38.0 0.0 2.3e-06 27.0 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EJP68451.1 - 8.3e-09 35.0 0.2 4e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EJP68451.1 - 3.7e-05 22.9 0.0 0.00013 21.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family COesterase PF00135.28 EJP68454.1 - 4.6e-96 322.7 0.0 5.9e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EJP68454.1 - 7e-08 32.6 0.4 9e-07 29.0 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EJP68454.1 - 0.02 14.4 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Chitin_bind_1 PF00187.19 EJP68455.1 - 9.3e-11 42.0 34.2 2.2e-08 34.4 17.2 2.7 2 0 0 2 2 2 2 Chitin recognition protein CAP PF00188.26 EJP68456.1 - 0.12 13.2 0.2 0.56 11.1 0.1 2.0 2 0 0 2 2 2 0 Cysteine-rich secretory protein family SKICH PF17751.1 EJP68458.1 - 0.042 14.4 0.1 29 5.3 0.0 3.2 3 0 0 3 3 3 0 SKICH domain fn3_PAP PF17808.1 EJP68458.1 - 0.09 12.9 0.2 24 5.1 0.0 2.8 3 0 0 3 3 3 0 Fn3-like domain from Purple Acid Phosphatase DUF4241 PF14025.6 EJP68458.1 - 0.95 9.7 3.9 0.61 10.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) Inositol_P PF00459.25 EJP68459.1 - 4.1e-31 108.5 0.0 7.6e-31 107.6 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family F-box PF00646.33 EJP68461.1 - 2.6e-07 30.4 0.1 7.1e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EJP68461.1 - 2.9e-07 30.3 8.3 2.9e-07 30.3 0.6 2.9 3 0 0 3 3 3 2 F-box-like MFS_1 PF07690.16 EJP68463.1 - 1.7e-14 53.6 24.9 1.7e-14 53.6 24.9 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EJP68463.1 - 5.3e-06 26.1 7.6 5.3e-06 26.1 7.6 2.8 2 2 0 2 2 2 1 Nodulin-like DUF4516 PF14990.6 EJP68463.1 - 0.084 12.6 0.2 0.26 11.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) 7tm_7 PF08395.12 EJP68463.1 - 2.9 7.0 6.9 0.76 8.9 0.1 3.0 3 1 0 4 4 4 0 7tm Chemosensory receptor Mre11_DNA_bind PF04152.14 EJP68464.1 - 1.6e-54 184.7 1.3 4.9e-54 183.2 1.3 1.9 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EJP68464.1 - 1.7e-14 54.8 0.9 3.1e-14 54.0 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP68464.1 - 0.00028 21.1 0.0 0.0022 18.2 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CN_hydrolase PF00795.22 EJP68465.1 - 2.6e-33 115.4 0.1 1.1e-27 97.1 0.0 2.9 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase WLM PF08325.10 EJP68466.1 - 3.3e-47 161.1 0.0 6.5e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EJP68466.1 - 0.00029 20.9 0.9 0.00063 19.8 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Reprolysin_5 PF13688.6 EJP68466.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Ubiquitin_2 PF14560.6 EJP68466.1 - 0.035 14.6 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain ubiquitin PF00240.23 EJP68466.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family SprT-like PF10263.9 EJP68466.1 - 0.078 12.8 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 SprT-like family Ada_Zn_binding PF02805.16 EJP68466.1 - 0.12 12.5 0.3 0.27 11.3 0.3 1.6 1 0 0 1 1 1 0 Metal binding domain of Ada Pkinase PF00069.25 EJP68468.1 - 7.5e-05 22.2 0.1 0.00075 18.9 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain ER_lumen_recept PF00810.18 EJP68469.1 - 8.3e-54 182.4 7.0 1.3e-53 181.8 7.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EJP68469.1 - 0.007 16.1 5.2 2.1 8.2 0.0 3.6 2 1 1 3 3 3 2 PQ loop repeat TFIID_30kDa PF03540.13 EJP68470.1 - 1.9e-26 91.7 0.5 2.9e-26 91.2 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EJP68470.1 - 0.043 14.4 0.9 0.093 13.3 0.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TAF4 PF05236.14 EJP68470.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Ribosomal_S19 PF00203.21 EJP68471.1 - 5.1e-27 93.6 0.0 5.9e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 MINDY_DUB PF04424.13 EJP68472.1 - 3.8e-22 78.5 0.0 6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Steroid_dh PF02544.16 EJP68473.1 - 3.5e-20 72.5 0.9 8.9e-14 51.7 0.6 2.4 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EJP68473.1 - 0.0037 16.8 2.3 0.0054 16.3 1.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Sugar_tr PF00083.24 EJP68474.1 - 2.1e-100 336.7 23.5 2.6e-100 336.5 23.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP68474.1 - 1.4e-25 90.0 30.1 1.5e-22 80.1 8.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EJP68474.1 - 0.0051 15.3 12.4 0.035 12.5 4.1 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Histone PF00125.24 EJP68475.1 - 3.6e-19 69.4 0.0 4.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EJP68475.1 - 2e-13 49.8 0.1 4.4e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EJP68475.1 - 4.5e-05 23.6 0.0 4.5e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 EJP68476.1 - 9.3e-11 41.6 0.2 1.8e-10 40.6 0.2 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EJP68476.1 - 6.5e-05 22.7 0.0 0.00015 21.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pheromone PF08015.11 EJP68476.1 - 7.6 7.7 6.5 19 6.4 0.0 3.9 3 0 0 3 3 3 0 Fungal mating-type pheromone ADH_zinc_N_2 PF13602.6 EJP68477.1 - 4.6e-19 69.8 0.1 9e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EJP68477.1 - 2.8e-14 53.2 0.5 1.6e-13 50.7 0.5 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EJP68477.1 - 0.03 14.2 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase ADH_N PF08240.12 EJP68477.1 - 0.038 13.9 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Striatin PF08232.12 EJP68478.1 - 7.1e-40 137.1 6.5 1.8e-39 135.8 6.5 1.7 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 EJP68478.1 - 2e-25 88.5 14.6 3.8e-05 24.4 0.6 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP68478.1 - 1e-06 28.9 0.0 0.55 10.6 0.0 4.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EJP68478.1 - 0.019 13.5 0.1 0.13 10.8 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain CALCOCO1 PF07888.11 EJP68478.1 - 0.036 13.0 8.0 0.06 12.2 8.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like eIF2A PF08662.11 EJP68478.1 - 0.093 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A ADH_N_2 PF16884.5 EJP68478.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase GFA PF04828.14 EJP68479.1 - 2.6e-17 62.9 4.4 7e-12 45.5 1.2 3.4 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Peptidase_S10 PF00450.22 EJP68480.1 - 2.7e-120 402.6 1.5 3.2e-120 402.4 1.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.25 EJP68481.1 - 8.3e-50 169.6 0.1 7.8e-34 117.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP68481.1 - 3.1e-21 75.8 0.5 6e-19 68.3 0.2 3.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP68481.1 - 9e-05 21.9 0.0 0.00022 20.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EJP68481.1 - 0.016 15.1 0.1 0.043 13.7 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glycos_transf_1 PF00534.20 EJP68482.1 - 4e-32 111.1 0.0 5.6e-19 68.3 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EJP68482.1 - 4.3e-14 52.9 0.2 1.2e-13 51.5 0.2 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EJP68482.1 - 3.3e-13 50.2 0.1 1.2e-12 48.5 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EJP68482.1 - 1.4e-06 28.9 7.1 4.9e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 EJP68482.1 - 3.3e-05 24.0 0.0 0.0098 16.0 0.0 3.0 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus ECH_1 PF00378.20 EJP68483.1 - 2.8e-11 43.2 0.0 8.2e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP68483.1 - 2.1e-05 24.2 0.0 0.00012 21.8 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase RabGAP-TBC PF00566.18 EJP68484.1 - 3.7e-45 154.2 0.0 6e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_4 PF12799.7 EJP68485.1 - 1.9e-21 75.8 31.2 0.00022 21.5 0.2 8.5 4 3 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EJP68485.1 - 9.7e-15 54.1 29.0 9.8e-05 22.0 2.2 6.7 4 2 1 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 EJP68485.1 - 1.6e-08 34.3 6.8 0.0093 15.5 0.2 3.7 3 0 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EJP68485.1 - 0.00091 19.1 6.5 16 5.8 0.0 6.2 5 0 0 5 5 5 1 Leucine Rich repeat NUP50 PF08911.11 EJP68485.1 - 0.017 15.8 0.2 0.071 13.8 0.2 2.1 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) LRR_1 PF00560.33 EJP68485.1 - 0.017 15.6 16.5 53 4.9 0.1 8.4 7 1 0 7 7 7 0 Leucine Rich Repeat IPK PF03770.16 EJP68487.1 - 9.7e-55 185.5 0.0 2.1e-54 184.4 0.0 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase Tex_YqgF PF16921.5 EJP68487.1 - 0.095 13.2 0.2 0.21 12.1 0.2 1.5 1 0 0 1 1 1 0 Tex protein YqgF-like domain DAO PF01266.24 EJP68488.1 - 2e-21 77.0 6.4 2.5e-21 76.7 6.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP68488.1 - 0.0059 16.8 0.2 0.024 14.9 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ras PF00071.22 EJP68489.1 - 4.1e-16 59.0 0.0 5.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP68489.1 - 0.00023 21.4 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EJP68489.1 - 0.0003 20.8 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Alg14 PF08660.11 EJP68490.1 - 1.8e-41 142.0 0.0 2.7e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like UL42 PF17638.2 EJP68490.1 - 0.0064 16.5 0.7 0.0064 16.5 0.7 1.9 1 1 1 2 2 2 1 HCMV UL42 JAMP PF05571.12 EJP68490.1 - 0.095 12.3 1.7 0.16 11.6 1.7 1.3 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Na_sulph_symp PF00939.19 EJP68490.1 - 0.13 11.3 4.0 0.19 10.7 4.0 1.2 1 0 0 1 1 1 0 Sodium:sulfate symporter transmembrane region MRP-S25 PF13741.6 EJP68491.1 - 2e-65 220.6 6.1 1.6e-61 207.8 1.5 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EJP68491.1 - 0.00038 20.7 1.7 0.0013 19.0 1.6 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 EJP68492.1 - 1.9e-16 60.0 0.5 1.1e-05 25.5 0.1 5.6 3 1 3 6 6 6 4 PPR repeat family PPR PF01535.20 EJP68492.1 - 1.5e-13 50.0 2.6 0.00042 20.4 0.0 5.7 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 EJP68492.1 - 5.7e-07 29.5 0.0 0.84 9.8 0.0 4.4 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EJP68492.1 - 8.5e-06 25.3 0.1 0.0004 19.8 0.1 2.3 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EJP68492.1 - 0.031 14.0 4.4 3.7 7.3 0.0 4.6 5 0 0 5 5 5 0 PPR repeat COX7C PF02935.16 EJP68493.1 - 1.1e-21 76.8 2.4 1.7e-21 76.2 2.4 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 EJP68494.1 - 3.9e-86 289.3 0.1 2.6e-85 286.6 0.0 2.3 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 EJP68494.1 - 1.9e-50 170.7 1.9 4.8e-50 169.4 1.9 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EJP68494.1 - 7.6e-19 68.1 0.0 1.9e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP68494.1 - 4.5e-06 27.0 0.0 1.5e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP68494.1 - 1.4e-05 25.2 0.0 4.7e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EJP68494.1 - 0.018 14.1 0.0 0.045 12.8 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EJP68494.1 - 0.056 13.7 0.0 0.24 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF2407_C PF13373.6 EJP68495.1 - 3.4e-32 111.5 0.2 4.6e-32 111.1 0.2 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EJP68495.1 - 4.7e-23 81.7 0.0 7.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EJP68495.1 - 8.8e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ima1_N PF09779.9 EJP68496.1 - 4.1e-36 124.8 2.0 4.1e-36 124.8 2.0 2.6 2 0 0 2 2 2 1 Ima1 N-terminal domain Casein_kappa PF00997.18 EJP68496.1 - 0.055 13.6 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 Kappa casein BSMAP PF12280.8 EJP68496.1 - 0.077 13.2 0.4 0.17 12.1 0.4 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein DZR PF12773.7 EJP68496.1 - 0.091 12.8 3.1 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF3040 PF11239.8 EJP68496.1 - 7.4 6.9 6.5 9.7 6.5 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) Y_phosphatase2 PF03162.13 EJP68497.1 - 3.7e-44 150.2 0.0 7.1e-44 149.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EJP68497.1 - 3.1e-09 37.1 0.2 1.4e-08 35.0 0.2 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EJP68497.1 - 1.1e-05 25.3 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJP68497.1 - 0.0077 15.8 0.0 0.022 14.3 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Pkinase PF00069.25 EJP68498.1 - 5e-12 45.7 0.0 7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EJP68498.1 - 7e-07 29.4 0.0 9.7e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EJP68498.1 - 0.0003 20.2 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EJP68498.1 - 0.0037 16.6 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EJP68498.1 - 0.0071 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EJP68498.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family HCO3_cotransp PF00955.21 EJP68499.1 - 1.4e-82 278.2 8.2 5.5e-45 154.1 2.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family TIMELESS PF04821.14 EJP68500.1 - 6.6e-87 291.3 0.0 6.6e-87 291.3 0.0 2.8 3 0 0 3 3 3 2 Timeless protein TIMELESS_C PF05029.13 EJP68500.1 - 1.8e-24 86.8 47.8 1.6e-23 83.7 18.4 4.5 2 1 1 3 3 3 1 Timeless protein C terminal region MIEAP PF16026.5 EJP68500.1 - 0.11 12.7 1.0 0.39 10.9 1.0 2.0 1 0 0 1 1 1 0 Mitochondria-eating protein 3HCDH_N PF02737.18 EJP68501.1 - 4.5e-52 176.5 1.0 5.9e-52 176.2 1.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EJP68501.1 - 4.7e-32 110.5 0.0 9.5e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 EJP68501.1 - 0.00024 21.4 0.4 0.00099 19.4 0.4 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 EJP68501.1 - 0.0022 17.3 0.1 0.0032 16.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP68501.1 - 0.0025 17.4 0.1 0.0035 17.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 EJP68501.1 - 0.02 15.1 0.3 0.058 13.6 0.3 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 EJP68501.1 - 0.023 15.3 0.1 0.049 14.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EJP68501.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EJP68501.1 - 0.058 13.0 0.1 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Acyl-CoA_dh_1 PF00441.24 EJP68502.1 - 3.6e-32 111.6 0.6 5.6e-32 111.0 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EJP68502.1 - 5.9e-23 80.9 0.1 1e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EJP68502.1 - 2.5e-16 60.4 0.0 8.8e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EJP68502.1 - 0.0037 17.5 0.1 0.0059 16.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Homeodomain PF00046.29 EJP68503.1 - 3e-18 65.4 3.5 5e-18 64.7 3.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EJP68503.1 - 0.00065 19.6 0.1 0.0018 18.2 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Rox3 PF08633.10 EJP68504.1 - 4.1e-69 233.0 0.9 4.4e-69 232.9 0.1 1.4 2 0 0 2 2 2 1 Rox3 mediator complex subunit Fungal_trans PF04082.18 EJP68505.1 - 7.8e-24 84.1 0.0 7.8e-24 84.1 0.0 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Med3 PF11593.8 EJP68505.1 - 8e-07 28.6 9.0 1.6e-06 27.6 9.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal efThoc1 PF11957.8 EJP68505.1 - 0.033 12.9 0.1 0.033 12.9 0.1 2.3 2 1 0 2 2 2 0 THO complex subunit 1 transcription elongation factor MecA PF05389.12 EJP68505.1 - 0.068 12.8 0.9 0.17 11.5 0.9 1.6 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Gal4_dimer PF03902.13 EJP68505.1 - 0.14 12.4 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain Suf PF05843.14 EJP68505.1 - 0.26 11.2 9.6 0.57 10.1 9.6 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 EJP68505.1 - 0.3 10.7 22.3 0.55 9.8 22.3 1.3 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 EJP68505.1 - 4.9 7.8 18.1 0.089 13.5 10.9 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PGAP1 PF07819.13 EJP68507.1 - 2.6e-06 27.4 0.1 1.5e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EJP68507.1 - 4.1e-06 27.6 0.1 1e-05 26.2 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EJP68507.1 - 9.8e-06 25.2 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EJP68507.1 - 0.0021 17.3 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP68507.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold RdRP_3 PF00998.23 EJP68507.1 - 0.017 13.9 6.4 0.026 13.3 6.4 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase Thioesterase PF00975.20 EJP68507.1 - 0.021 15.0 2.7 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain UPF0227 PF05728.12 EJP68507.1 - 0.021 14.8 0.1 0.05 13.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.8 EJP68507.1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 EJP68507.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 EJP68507.1 - 0.3 10.4 2.7 11 5.2 0.0 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) DDRGK PF09756.9 EJP68507.1 - 1.2 8.7 25.9 2.3 7.8 25.9 1.4 1 0 0 1 1 1 0 DDRGK domain Fibin PF15819.5 EJP68507.1 - 1.3 8.7 6.4 2.4 7.9 6.4 1.3 1 0 0 1 1 1 0 Fin bud initiation factor homologue HET PF06985.11 EJP68508.1 - 9.6e-15 55.2 0.0 2.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 EJP68509.1 - 6.2e-14 51.4 0.2 4e-13 48.8 0.2 1.9 1 1 0 1 1 1 1 AMP-binding enzyme DEAD PF00270.29 EJP68510.1 - 3.2e-48 163.8 0.0 8.6e-48 162.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP68510.1 - 2.4e-32 111.6 0.0 5.8e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP68510.1 - 0.0027 17.8 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EJP68510.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EJP68510.1 - 0.2 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 EJP68510.1 - 0.25 10.1 0.0 0.44 9.3 0.0 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF3328 PF11807.8 EJP68512.1 - 1.1e-38 133.3 0.7 1.3e-38 133.0 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Citrate_synt PF00285.21 EJP68513.1 - 3e-124 414.7 0.0 3.8e-124 414.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Malate_synthase PF01274.22 EJP68514.1 - 8e-229 760.3 0.0 9e-229 760.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Pkinase PF00069.25 EJP68515.1 - 3.7e-64 216.6 0.1 3.1e-63 213.6 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 EJP68515.1 - 1.7e-40 137.4 0.3 4.2e-40 136.1 0.3 1.7 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 EJP68515.1 - 2.8e-33 115.3 0.0 1.5e-32 113.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP68515.1 - 2.2e-07 30.5 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EJP68515.1 - 0.00031 19.8 0.1 0.00077 18.5 0.1 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EJP68515.1 - 0.0027 17.1 1.3 0.0047 16.3 0.2 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EJP68515.1 - 0.047 13.3 1.8 0.23 11.0 0.1 2.7 3 0 0 3 3 3 0 Choline/ethanolamine kinase APH PF01636.23 EJP68515.1 - 0.073 13.0 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family SMC_N PF02463.19 EJP68516.1 - 1.9e-26 92.8 0.0 4.3e-26 91.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP68516.1 - 1.4e-14 55.1 18.2 1.4e-14 55.1 18.2 4.9 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 EJP68516.1 - 6.3e-10 39.4 0.6 0.00094 19.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EJP68516.1 - 1.3e-06 28.4 15.8 5.6e-06 26.3 2.8 2.4 2 0 0 2 2 2 2 AAA ATPase domain TF_AP-2 PF03299.14 EJP68516.1 - 0.00026 21.0 3.8 0.00026 21.0 3.8 2.9 2 0 0 2 2 2 1 Transcription factor AP-2 AAA_29 PF13555.6 EJP68516.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF948 PF06103.11 EJP68516.1 - 0.2 11.9 8.0 12 6.3 0.4 4.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) AAA PF00004.29 EJP68516.1 - 0.66 10.4 3.4 0.67 10.4 0.2 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EJP68516.1 - 1.2 8.7 0.0 1.2 8.7 0.0 4.3 3 1 0 4 4 4 0 AAA domain Baculo_PEP_C PF04513.12 EJP68516.1 - 5.6 7.0 16.2 8.5 6.4 0.1 5.0 3 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_4 PF13418.6 EJP68517.1 - 9.7e-31 105.5 5.5 6.6e-05 22.8 0.4 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EJP68517.1 - 3.3e-26 90.7 5.0 1.4e-09 37.8 0.5 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EJP68517.1 - 5.2e-23 80.4 4.5 1.8e-09 37.0 0.3 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 EJP68517.1 - 6e-23 80.4 16.2 1e-06 28.6 0.1 6.8 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 EJP68517.1 - 4.3e-22 77.9 22.1 1.4e-05 25.2 0.1 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EJP68517.1 - 2.6e-17 62.0 7.0 1.4e-06 28.0 0.3 6.5 6 0 0 6 6 6 3 Kelch motif EzrA PF06160.12 EJP68517.1 - 0.0021 16.3 14.8 0.0021 16.3 14.8 3.6 3 0 0 3 3 3 2 Septation ring formation regulator, EzrA FANCD2OS PF15124.6 EJP68517.1 - 0.76 10.0 2.9 0.51 10.5 0.3 2.1 2 0 0 2 2 2 0 FANCD2 opposite strand protein XhlA PF10779.9 EJP68517.1 - 3.1 8.1 13.4 9.8 6.5 0.1 5.0 3 1 1 4 4 4 0 Haemolysin XhlA Pkinase PF00069.25 EJP68518.1 - 2.9e-68 230.1 0.0 4e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP68518.1 - 1.4e-36 126.2 0.0 2.2e-36 125.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP68518.1 - 0.0015 17.9 0.1 0.0026 17.1 0.1 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EJP68518.1 - 0.0076 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EJP68518.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EJP68518.1 - 0.067 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EJP68518.1 - 0.1 12.5 0.5 1.1 9.2 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Abhydrolase_1 PF00561.20 EJP68519.1 - 8.8e-13 48.5 0.0 2.9e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP68519.1 - 9.4e-10 38.2 0.0 1.9e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 EJP68519.1 - 0.15 11.5 0.6 4.1 6.9 0.0 2.2 1 1 1 2 2 2 0 Lipase (class 2) DUF1456 PF07308.13 EJP68520.1 - 0.14 12.6 1.8 14 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) DUF5301 PF17225.3 EJP68520.1 - 0.26 11.8 7.0 0.36 11.3 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) IF4E PF01652.18 EJP68521.1 - 2.5e-53 180.1 0.0 3.4e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E UCH PF00443.29 EJP68522.1 - 5.9e-23 81.7 0.0 8.6e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EJP68522.1 - 8.3e-12 45.3 0.1 1.9e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF1064 PF06356.11 EJP68522.1 - 0.044 14.1 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) UCH_1 PF13423.6 EJP68522.1 - 0.059 13.0 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Utp13 PF08625.11 EJP68523.1 - 4.1e-53 179.1 0.3 6.4e-53 178.5 0.3 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 EJP68523.1 - 3.9e-44 147.7 34.8 5.2e-06 27.1 0.2 12.1 12 1 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP68523.1 - 1.7e-10 41.1 11.5 0.084 13.2 0.1 8.3 6 3 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP68523.1 - 3.1e-05 22.8 5.4 0.44 9.1 0.1 5.1 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EJP68523.1 - 5e-05 22.2 7.2 1.3 7.7 0.0 5.6 3 3 1 6 6 6 3 Nup133 N terminal like MCM PF00493.23 EJP68525.1 - 5.4e-105 349.4 0.2 1.6e-104 347.9 0.1 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EJP68525.1 - 1.4e-36 125.1 0.3 2.5e-36 124.3 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EJP68525.1 - 2.6e-27 95.1 1.4 6.6e-27 93.8 1.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EJP68525.1 - 2.8e-15 56.8 0.7 6.7e-15 55.5 0.7 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EJP68525.1 - 9.3e-07 28.4 0.0 0.00017 21.1 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EJP68525.1 - 1.4e-05 25.1 0.0 4.2e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EJP68525.1 - 6.4e-05 22.8 0.2 0.00035 20.5 0.0 2.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EJP68525.1 - 0.019 15.4 0.1 0.078 13.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJP68525.1 - 0.055 13.2 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Vps54 PF07928.12 EJP68526.1 - 2.3e-52 177.0 0.6 5.5e-52 175.7 0.1 2.0 2 0 0 2 2 1 1 Vps54-like protein Vps54_N PF10475.9 EJP68526.1 - 6.8e-06 25.6 2.8 9.2e-06 25.1 0.9 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex LUC7 PF03194.15 EJP68526.1 - 0.012 15.3 0.5 0.038 13.6 0.5 1.8 1 0 0 1 1 1 0 LUC7 N_terminus FliJ PF02050.16 EJP68526.1 - 0.017 15.3 2.3 0.017 15.3 2.3 3.2 3 0 0 3 3 3 0 Flagellar FliJ protein DUF2451 PF10474.9 EJP68526.1 - 0.018 14.8 0.0 0.067 13.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) DUF4363 PF14276.6 EJP68526.1 - 0.02 15.0 0.5 0.37 10.9 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Sec8_exocyst PF04048.14 EJP68526.1 - 0.062 13.2 0.5 0.2 11.5 0.5 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Helo_like_N PF17111.5 EJP68526.1 - 0.066 12.6 2.7 0.79 9.1 0.9 3.3 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins COG2 PF06148.11 EJP68526.1 - 0.41 10.7 3.4 2.3 8.3 1.4 3.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6_N PF17675.1 EJP68526.1 - 3.2 8.3 12.9 1.2 9.7 2.2 3.1 2 0 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 EJP68526.1 - 3.6 8.3 4.5 5.6 7.6 0.3 3.4 3 0 0 3 3 3 0 Initiation control protein YabA MCPsignal PF00015.21 EJP68526.1 - 4.5 7.0 8.7 20 5.0 2.8 2.7 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MFS_1 PF07690.16 EJP68528.1 - 5e-36 124.4 48.2 1.7e-30 106.2 26.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EJP68528.1 - 1.1e-06 27.7 1.1 1.1e-06 27.7 1.1 3.0 1 1 0 3 3 3 1 MFS_1 like family polyprenyl_synt PF00348.17 EJP68529.1 - 8.1e-90 300.3 0.0 1.2e-89 299.8 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase ANAPC8 PF04049.13 EJP68531.1 - 2.2e-57 193.0 0.1 5.4e-57 191.8 0.1 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 EJP68531.1 - 3.1e-22 76.9 5.0 6.9e-05 22.7 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EJP68531.1 - 2.3e-20 71.5 3.5 8.7e-05 22.2 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP68531.1 - 8.3e-16 56.8 11.9 0.03 14.4 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 EJP68531.1 - 2.1e-09 37.4 11.2 0.0057 17.4 0.1 8.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJP68531.1 - 3.1e-09 37.3 1.7 2.4e-05 24.9 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJP68531.1 - 2.6e-08 33.4 0.0 1.1e-06 28.2 0.1 2.9 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 EJP68531.1 - 1.8e-06 28.1 17.8 0.26 11.6 0.1 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP68531.1 - 6.9e-06 25.7 7.1 0.045 13.8 0.0 6.2 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP68531.1 - 1.4e-05 25.5 1.9 6.1 7.4 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP68531.1 - 9.6e-05 22.5 10.2 0.045 14.0 0.5 5.5 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 EJP68531.1 - 0.0009 19.3 0.8 0.098 12.7 0.1 3.0 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 EJP68531.1 - 0.0022 18.5 10.9 1 10.2 0.1 7.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 EJP68531.1 - 0.0076 16.6 0.0 6.5 7.4 0.0 4.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EJP68531.1 - 0.011 15.9 10.2 2.2 8.5 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 EJP68531.1 - 0.071 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_10 PF13374.6 EJP68531.1 - 0.076 12.9 0.8 41 4.2 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PH PF00169.29 EJP68532.1 - 3.9e-05 24.1 0.1 0.00012 22.6 0.1 1.8 1 0 0 1 1 1 1 PH domain RmlD_sub_bind PF04321.17 EJP68533.1 - 1.1e-57 195.3 0.0 1.4e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EJP68533.1 - 8.6e-23 81.0 0.0 1.1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP68533.1 - 2.3e-12 47.0 0.0 1.3e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EJP68533.1 - 9.6e-11 41.3 0.0 6e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EJP68533.1 - 2.4e-09 36.6 0.0 7.7e-09 35.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EJP68533.1 - 4.8e-09 35.8 0.1 1.1e-06 28.0 0.0 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EJP68533.1 - 0.029 13.9 0.3 0.26 10.8 0.2 2.5 2 1 0 2 2 2 0 NmrA-like family KR PF08659.10 EJP68533.1 - 0.029 14.3 0.1 2.3 8.1 0.1 2.4 1 1 1 2 2 2 0 KR domain NAD_binding_10 PF13460.6 EJP68533.1 - 0.063 13.2 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding MFAP1 PF06991.11 EJP68534.1 - 1.7e-50 171.9 22.1 1.7e-50 171.9 22.1 3.8 3 1 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing Pol_alpha_B_N PF08418.10 EJP68535.1 - 6.5e-78 262.1 0.0 8.2e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EJP68535.1 - 4.3e-37 127.5 0.0 6.7e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B GATA PF00320.27 EJP68536.1 - 0.0028 17.2 7.9 0.017 14.7 0.9 2.6 2 0 0 2 2 2 2 GATA zinc finger ECH_2 PF16113.5 EJP68537.1 - 1.4e-126 422.5 0.0 1.8e-126 422.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EJP68537.1 - 3e-25 89.0 0.0 7e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase LSM PF01423.22 EJP68538.1 - 9.2e-18 63.7 0.1 1.3e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EJP68538.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Dak1 PF02733.17 EJP68539.1 - 2.5e-101 338.7 8.2 3.4e-101 338.2 8.2 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EJP68539.1 - 3e-46 157.5 2.0 3.2e-46 157.4 0.1 2.1 2 0 0 2 2 2 1 DAK2 domain Glyco_hydro_76 PF03663.14 EJP68540.1 - 7.1e-140 466.7 10.2 8.3e-140 466.4 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Abhydrolase_3 PF07859.13 EJP68541.1 - 4.3e-37 128.0 0.6 1.1e-36 126.7 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP68541.1 - 0.077 11.8 0.0 0.81 8.5 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase DUF4188 PF13826.6 EJP68542.1 - 2.4e-26 92.4 0.0 3.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EJP68542.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase Phosphodiest PF01663.22 EJP68542.1 - 0.067 12.8 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4048 PF13257.6 EJP68543.1 - 3.5e-09 36.9 0.4 3.5e-09 36.9 0.4 5.2 4 2 1 6 6 6 2 Domain of unknown function (DUF4048) ABC_tran PF00005.27 EJP68544.1 - 9.4e-40 136.3 2.2 1.1e-20 74.5 0.0 3.7 4 1 0 4 4 3 2 ABC transporter ABC_membrane PF00664.23 EJP68544.1 - 1.2e-27 97.2 17.1 3.9e-18 66.1 7.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP68544.1 - 3.2e-13 49.6 0.3 6.2e-07 29.1 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EJP68544.1 - 1.1e-05 24.7 0.3 0.038 13.1 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EJP68544.1 - 3.6e-05 23.8 0.5 0.36 10.9 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EJP68544.1 - 0.0001 21.9 2.3 0.061 13.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EJP68544.1 - 0.00026 20.9 0.3 0.071 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EJP68544.1 - 0.00043 20.8 5.6 0.41 11.1 0.0 2.6 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EJP68544.1 - 0.00075 19.4 0.6 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 EJP68544.1 - 0.0013 18.9 3.1 0.16 12.0 0.1 2.8 3 0 0 3 3 3 1 Helicase HerA, central domain Dynamin_N PF00350.23 EJP68544.1 - 0.0013 18.8 2.3 0.061 13.4 0.2 2.7 3 0 0 3 3 2 1 Dynamin family AIG1 PF04548.16 EJP68544.1 - 0.0014 18.0 0.2 1.5 8.1 0.1 2.5 2 0 0 2 2 2 2 AIG1 family AAA_24 PF13479.6 EJP68544.1 - 0.0018 18.0 0.3 2.4 7.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EJP68544.1 - 0.0041 17.4 0.5 2 8.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJP68544.1 - 0.0056 17.1 0.3 11 6.4 0.0 3.9 4 0 0 4 4 4 0 AAA ATPase domain AAA_7 PF12775.7 EJP68544.1 - 0.02 14.4 0.3 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PEN-2 PF10251.9 EJP68544.1 - 0.036 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase AAA PF00004.29 EJP68544.1 - 0.042 14.3 0.0 2.6 8.5 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EJP68544.1 - 0.043 14.2 0.1 13 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 EJP68544.1 - 0.14 11.5 0.1 14 4.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 EJP68544.1 - 0.15 11.7 0.9 6.6 6.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EJP68544.1 - 0.19 11.6 1.1 3 7.7 0.0 2.7 3 0 0 3 3 3 0 NTPase BatA PF07584.11 EJP68544.1 - 0.68 10.3 0.0 0.68 10.3 0.0 2.9 3 0 0 3 3 2 0 Aerotolerance regulator N-terminal DUF4246 PF14033.6 EJP68545.1 - 2.6e-96 323.5 0.6 2.5e-73 247.7 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EJP68545.1 - 0.32 11.4 1.6 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Pox_Ag35 PF03286.14 EJP68545.1 - 5.5 6.7 11.6 6.1 6.6 1.0 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ferritin_2 PF13668.6 EJP68546.1 - 9.7e-38 129.4 0.3 1.4e-37 128.9 0.3 1.2 1 0 0 1 1 1 1 Ferritin-like domain MKT1_C PF12246.8 EJP68547.1 - 8.5e-71 238.0 0.0 1.3e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EJP68547.1 - 1.7e-32 111.6 0.0 3.4e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EJP68547.1 - 0.00038 20.9 0.0 0.0012 19.3 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain TcdA_TcdB_pore PF12920.7 EJP68547.1 - 0.06 11.6 0.0 0.099 10.9 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF5539 PF17693.1 EJP68548.1 - 0.049 13.3 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) APH PF01636.23 EJP68550.1 - 1.6e-18 67.5 0.0 2.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP68550.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase adh_short PF00106.25 EJP68551.1 - 2.1e-07 30.6 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP68551.1 - 2.6e-06 27.5 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EJP68551.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_2 PF07992.14 EJP68552.1 - 4e-18 65.7 0.0 4.3e-17 62.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP68552.1 - 5e-06 25.9 1.0 0.00021 20.5 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EJP68552.1 - 6.4e-05 22.3 0.2 0.0086 15.4 0.7 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP68552.1 - 6.5e-05 23.0 0.4 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EJP68552.1 - 0.00014 20.7 0.3 0.0055 15.5 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EJP68552.1 - 0.00024 21.3 0.0 0.00056 20.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EJP68552.1 - 0.00064 19.4 0.6 0.0021 17.7 0.3 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP68552.1 - 0.00085 18.5 0.1 0.23 10.4 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 EJP68552.1 - 0.0022 17.3 1.4 0.0032 16.8 0.8 1.6 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.17 EJP68552.1 - 0.0044 16.3 0.1 0.0075 15.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EJP68552.1 - 0.037 13.4 0.3 0.066 12.5 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4554 PF15091.6 EJP68552.1 - 0.078 11.9 0.0 0.35 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) GIDA PF01134.22 EJP68552.1 - 0.46 9.5 6.9 0.069 12.2 1.3 2.2 2 1 1 3 3 3 0 Glucose inhibited division protein A ABC2_membrane PF01061.24 EJP68554.1 - 6.2e-80 267.5 42.9 3.5e-43 147.5 18.7 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EJP68554.1 - 6.1e-39 133.7 0.0 3e-19 69.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EJP68554.1 - 5.1e-28 96.8 0.5 4.8e-22 77.7 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EJP68554.1 - 8.9e-14 51.3 26.9 6e-08 32.2 12.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 EJP68554.1 - 3.7e-09 37.1 1.8 6.9e-09 36.2 0.1 2.4 3 0 0 3 3 2 1 ABC-transporter N-terminal AAA_25 PF13481.6 EJP68554.1 - 5.6e-05 22.8 0.1 0.011 15.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EJP68554.1 - 7.4e-05 22.7 0.2 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EJP68554.1 - 7.9e-05 23.1 0.1 0.011 16.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EJP68554.1 - 0.00034 21.1 0.0 0.57 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJP68554.1 - 0.0011 18.7 0.1 0.065 13.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EJP68554.1 - 0.0012 18.7 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EJP68554.1 - 0.0022 18.2 0.6 0.15 12.3 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EJP68554.1 - 0.0063 16.8 0.3 0.52 10.6 0.1 2.9 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EJP68554.1 - 0.015 15.4 0.1 1.1 9.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 EJP68554.1 - 0.044 13.5 0.7 3.4 7.4 0.4 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EJP68554.1 - 0.055 13.1 1.3 4.3 6.9 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EJP68554.1 - 0.085 12.9 0.1 17 5.5 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EJP68554.1 - 0.13 12.2 0.6 2.2 8.2 0.2 2.4 2 0 0 2 2 2 0 NACHT domain ABC2_membrane_2 PF12679.7 EJP68554.1 - 2.9 7.1 13.0 0.64 9.2 6.9 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Fungal_trans PF04082.18 EJP68555.1 - 3e-23 82.2 0.1 5e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Esterase_phd PF10503.9 EJP68556.1 - 0.0065 16.0 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 EJP68556.1 - 0.14 12.0 0.2 0.42 10.4 0.2 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 EJP68556.1 - 0.2 10.3 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DSPc PF00782.20 EJP68558.1 - 7.3e-26 90.6 0.1 9.7e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJP68558.1 - 0.00084 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EJP68558.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Dioxygenase_C PF00775.21 EJP68559.1 - 8.5e-43 145.9 0.0 1.4e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EJP68559.1 - 1.5e-33 114.5 0.0 2.8e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EJP68559.1 - 0.094 13.0 0.0 0.34 11.2 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain AdoMet_MTase PF07757.13 EJP68560.1 - 2.1e-38 131.1 0.0 3.1e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EJP68560.1 - 0.068 13.2 0.2 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EJP68560.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ank_4 PF13637.6 EJP68562.1 - 5.9e-06 26.7 1.7 1.1 9.9 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJP68562.1 - 4.5e-05 24.0 0.0 1.1 9.9 0.0 4.3 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP68562.1 - 0.0085 16.4 0.8 19 5.7 0.0 4.9 4 2 2 6 6 6 1 Ankyrin repeats (many copies) F-box-like PF12937.7 EJP68562.1 - 0.053 13.4 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like ATP-sulfurylase PF01747.17 EJP68563.1 - 5.8e-89 297.2 0.3 8.1e-89 296.7 0.3 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EJP68563.1 - 4e-57 192.5 0.0 6.3e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EJP68563.1 - 2.1e-54 183.5 0.0 3.3e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CPT PF07931.12 EJP68563.1 - 0.074 12.9 0.0 0.75 9.6 0.0 2.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EJP68563.1 - 0.091 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EJP68563.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TRP PF06011.12 EJP68564.1 - 4.3e-106 355.2 18.7 6.3e-106 354.6 18.7 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EJP68564.1 - 2.7e-35 121.7 0.0 4.5e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Zn_clus PF00172.18 EJP68565.1 - 1e-07 31.9 10.9 1e-07 31.9 10.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2510 PF10708.9 EJP68565.1 - 1.1 9.1 3.8 6.4 6.6 3.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2510) adh_short_C2 PF13561.6 EJP68566.1 - 2.8e-51 174.3 0.3 3.4e-51 174.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP68566.1 - 7.5e-40 136.5 0.0 9.2e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP68566.1 - 3.8e-14 53.0 0.4 6.6e-14 52.2 0.4 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP68566.1 - 0.0043 16.5 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 EJP68566.1 - 0.034 14.6 0.0 0.084 13.4 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3Beta_HSD PF01073.19 EJP68566.1 - 0.059 12.4 0.1 0.23 10.4 0.0 1.8 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Preseq_ALAS PF09029.10 EJP68568.1 - 0.0033 17.9 0.2 0.0076 16.7 0.2 1.6 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Pan3_PK PF18101.1 EJP68569.1 - 2.3e-63 212.2 0.1 3.6e-63 211.6 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EJP68569.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-CCCH PF00642.24 EJP68569.1 - 0.0096 15.8 0.7 0.017 15.0 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase_Tyr PF07714.17 EJP68569.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase LSM PF01423.22 EJP68570.1 - 4.9e-22 77.4 0.2 6.8e-22 76.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 EJP68570.1 - 0.018 15.5 7.3 0.032 14.8 7.3 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Cut12 PF11500.8 EJP68571.1 - 3e-37 127.8 14.3 3e-37 127.8 14.3 3.6 1 1 2 3 3 3 1 Spindle pole body formation-associated protein Pox_A_type_inc PF04508.12 EJP68571.1 - 0.013 15.3 1.0 1 9.3 0.3 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Exonuc_VII_L PF02601.15 EJP68571.1 - 0.58 9.7 21.0 2.3 7.7 0.2 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fez1 PF06818.15 EJP68571.1 - 1.3 9.5 46.9 0.037 14.5 6.4 3.3 1 1 1 3 3 3 0 Fez1 Rx_N PF18052.1 EJP68571.1 - 8.5 6.7 10.7 3.4 8.0 1.1 3.3 2 1 0 3 3 3 0 Rx N-terminal domain SesA PF17107.5 EJP68571.1 - 8.6 6.6 14.6 12 6.1 4.1 3.5 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases UreF PF01730.16 EJP68572.1 - 1.5e-22 80.6 0.0 3e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 UreF Sugarporin_N PF11471.8 EJP68572.1 - 0.0028 17.6 2.6 0.011 15.6 2.6 2.0 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension DUF429 PF04250.13 EJP68572.1 - 0.032 14.0 0.4 0.059 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF429) SlyX PF04102.12 EJP68572.1 - 0.18 12.4 0.6 0.38 11.4 0.6 1.5 1 0 0 1 1 1 0 SlyX Torus PF16131.5 EJP68573.1 - 1.8e-39 134.8 0.0 5e-39 133.4 0.0 1.8 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 EJP68573.1 - 2.4e-08 33.7 0.0 4.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EJP68573.1 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 EJP68573.1 - 0.013 15.6 0.1 0.013 15.6 0.1 1.8 2 0 0 2 2 2 0 Zinc finger domain HAT PF02184.16 EJP68575.1 - 0.015 15.3 1.3 0.015 15.3 1.3 2.0 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat DnaJ_C PF01556.18 EJP68576.1 - 3.6e-38 131.0 0.8 4.8e-38 130.5 0.8 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJP68576.1 - 1.1e-26 92.7 2.7 1.9e-26 92.0 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_79C PF16862.5 EJP68577.1 - 1.1e-18 68.0 2.3 2.1e-18 67.1 2.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Ala_racemase_C PF00842.21 EJP68577.1 - 0.088 12.6 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Fe_bilin_red PF05996.12 EJP68578.1 - 0.051 13.3 0.2 0.08 12.6 0.2 1.3 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase PP2C_C PF07830.13 EJP68578.1 - 0.14 12.6 1.0 6.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Actin_micro PF17003.5 EJP68578.1 - 7.5 5.6 7.4 9.3 5.3 7.4 1.2 1 0 0 1 1 1 0 Putative actin-like family FA_hydroxylase PF04116.13 EJP68579.1 - 8.4e-22 77.9 12.0 8.4e-22 77.9 12.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HAD_2 PF13419.6 EJP68580.1 - 4.7e-23 82.2 0.0 5.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP68580.1 - 1.4e-09 38.5 0.1 4.1e-09 37.0 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EJP68580.1 - 5.7e-08 32.7 0.0 1.9e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 EJP68580.1 - 4.5e-05 23.4 0.0 8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DnaG_DnaB_bind PF08278.11 EJP68580.1 - 0.031 14.9 0.1 0.047 14.3 0.1 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Hydrolase_6 PF13344.6 EJP68580.1 - 0.11 12.6 0.0 17 5.6 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Rit1_C PF17184.4 EJP68581.1 - 6e-100 334.2 0.0 7.8e-100 333.8 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EJP68581.1 - 6.4e-31 106.9 0.0 1.3e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain GFO_IDH_MocA PF01408.22 EJP68582.1 - 4.5e-09 37.2 0.1 2.8e-08 34.6 0.1 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 EJP68582.1 - 0.14 12.7 0.0 0.39 11.2 0.0 1.7 2 0 0 2 2 2 0 CoA binding domain DHDPS PF00701.22 EJP68583.1 - 3.6e-36 124.4 0.0 4.8e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peptidase_M43 PF05572.13 EJP68584.1 - 8.6e-11 42.0 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 EJP68584.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EJP68584.1 - 0.019 15.5 0.1 0.036 14.6 0.1 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EJP68584.1 - 0.061 12.5 0.3 0.45 9.7 0.3 2.1 2 0 0 2 2 2 0 Met-zincin Peptidase_M57 PF12388.8 EJP68584.1 - 0.11 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 EJP68584.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Nop16 PF09420.10 EJP68586.1 - 9.9e-67 225.0 7.7 1.5e-66 224.5 7.7 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 AAA_10 PF12846.7 EJP68586.1 - 0.059 12.3 0.1 0.059 12.3 0.1 1.5 2 0 0 2 2 2 0 AAA-like domain GATase_4 PF13230.6 EJP68587.1 - 4.6e-17 61.8 0.1 1.8e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 EJP68587.1 - 3.5e-10 40.2 0.0 5.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Fungal_trans_2 PF11951.8 EJP68589.1 - 8.3e-46 156.5 0.4 5.9e-45 153.7 0.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP68589.1 - 3.3e-07 30.3 7.1 7.5e-07 29.2 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 EJP68590.1 - 2.3e-59 201.4 0.2 2.3e-59 201.4 0.2 3.3 2 1 1 3 3 3 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP68590.1 - 8.1e-10 39.2 0.2 8.1e-10 39.2 0.2 4.8 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EJP68590.1 - 0.0016 18.3 0.0 0.085 12.6 0.0 2.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal GSHPx PF00255.19 EJP68591.1 - 5.7e-42 141.7 0.1 7.2e-42 141.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EJP68591.1 - 0.0014 18.5 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJP68591.1 - 0.008 15.9 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 1 Redoxin Ral PF11058.8 EJP68591.1 - 0.042 13.4 0.1 0.088 12.4 0.1 1.5 1 0 0 1 1 1 0 Antirestriction protein Ral DAO PF01266.24 EJP68592.1 - 1e-62 212.8 2.6 1.3e-62 212.5 2.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP68592.1 - 0.00011 22.4 0.1 0.00027 21.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP68592.1 - 0.00061 20.3 1.6 0.83 10.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP68592.1 - 0.00065 19.0 0.4 0.52 9.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EJP68592.1 - 0.0026 16.6 0.7 0.59 8.9 0.2 2.1 2 0 0 2 2 2 2 MCRA family Mqo PF06039.15 EJP68592.1 - 0.0065 15.1 0.0 2.1 6.8 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 EJP68592.1 - 0.073 12.1 2.5 0.17 10.9 2.5 1.7 1 1 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EJP68592.1 - 0.15 10.9 0.5 9.1 5.0 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.16 EJP68593.1 - 1.4e-41 142.7 47.0 2.2e-41 141.9 47.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68593.1 - 4.1e-18 65.5 33.9 4.7e-18 65.3 10.1 2.9 2 2 0 3 3 3 2 Sugar (and other) transporter SAYSvFN PF10260.9 EJP68593.1 - 0.034 14.1 0.2 15 5.6 0.1 3.1 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) MccV PF17508.2 EJP68593.1 - 6.7 7.3 11.2 4.1 8.0 0.1 4.1 4 0 0 4 4 4 0 Microcin V bacteriocin DUF4191 PF13829.6 EJP68593.1 - 7.3 5.9 6.8 0.72 9.1 0.3 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4191) MARVEL PF01284.23 EJP68594.1 - 0.0049 16.9 11.5 0.0049 16.9 11.5 2.0 2 0 0 2 2 2 1 Membrane-associating domain Granulin PF00396.18 EJP68594.1 - 0.056 13.8 15.6 0.062 13.6 5.3 2.5 2 0 0 2 2 2 0 Granulin DUF4281 PF14108.6 EJP68594.1 - 1 9.7 5.4 0.24 11.8 1.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4281) WD40 PF00400.32 EJP68595.1 - 7.6e-14 51.9 2.2 0.00024 21.8 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP68595.1 - 2.3e-05 24.6 0.0 0.26 11.6 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Heme_oxygenase PF01126.20 EJP68596.1 - 3.3e-09 36.9 0.0 5.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Heme oxygenase Zn_clus PF00172.18 EJP68597.1 - 0.00011 22.3 9.0 0.00018 21.5 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EJP68598.1 - 2.2e-39 135.4 41.1 1e-36 126.6 26.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily EamA PF00892.20 EJP68599.1 - 5.7e-13 49.2 37.0 6.1e-07 29.7 4.8 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 EJP68599.1 - 2.5e-09 36.8 3.1 2.5e-09 36.8 3.1 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) UAA PF08449.11 EJP68599.1 - 1.8e-06 27.4 12.7 1.8e-06 27.4 12.7 1.4 2 0 0 2 2 2 1 UAA transporter family PUNUT PF16913.5 EJP68599.1 - 3.2e-06 26.6 1.2 3.2e-06 26.6 1.2 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 EJP68599.1 - 0.0003 20.4 14.1 0.0003 20.4 14.1 1.5 2 0 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 EJP68599.1 - 0.0075 15.3 7.4 0.024 13.6 1.0 2.4 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like HsbA PF12296.8 EJP68600.1 - 2.3e-20 73.2 4.5 2.3e-20 73.2 4.5 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 EJP68600.1 - 0.11 12.5 1.6 1.5 8.8 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NMT1 PF09084.11 EJP68601.1 - 0.11 12.5 0.0 0.42 10.5 0.0 2.0 1 1 0 1 1 1 0 NMT1/THI5 like Copper-fist PF00649.18 EJP68602.1 - 7.1e-20 70.2 3.5 7.1e-20 70.2 3.5 2.3 1 1 1 2 2 2 1 Copper fist DNA binding domain Pro-kuma_activ PF09286.11 EJP68603.1 - 1.3e-26 93.6 0.0 2.5e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EJP68603.1 - 1.8e-07 30.7 3.2 3.3e-07 29.9 3.2 1.3 1 0 0 1 1 1 1 Subtilase family ABC_tran PF00005.27 EJP68604.1 - 2.7e-40 138.0 0.1 7e-20 71.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP68604.1 - 1.3e-27 97.2 20.0 5.5e-20 72.1 8.2 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP68604.1 - 9.8e-07 28.4 3.7 0.00014 21.4 0.3 3.7 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EJP68604.1 - 2.5e-05 24.3 0.1 0.027 14.4 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_21 PF13304.6 EJP68604.1 - 0.0018 18.1 1.5 3.3 7.4 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP68604.1 - 0.0051 16.5 4.4 0.87 9.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJP68604.1 - 0.0057 16.7 2.5 0.47 10.5 0.3 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 EJP68604.1 - 0.0078 16.4 3.1 2 8.7 0.0 3.5 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EJP68604.1 - 0.039 14.4 0.3 1.9 9.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EJP68604.1 - 0.18 11.5 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain YebO PF13974.6 EJP68604.1 - 0.55 10.3 1.9 1.3 9.2 0.2 2.6 3 0 0 3 3 3 0 YebO-like protein DUF87 PF01935.17 EJP68604.1 - 5.3 7.1 5.9 6.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain APH PF01636.23 EJP68605.1 - 0.0036 17.2 1.3 1.9 8.4 0.4 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family MFS_1 PF07690.16 EJP68607.1 - 3e-26 92.2 42.9 4.4e-20 71.9 22.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68607.1 - 0.00061 18.8 2.2 0.00061 18.8 2.2 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter IL2 PF00715.17 EJP68607.1 - 0.061 13.3 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Interleukin 2 GCIP PF13324.6 EJP68608.1 - 8.2 5.9 12.1 7.6 6.1 3.6 2.4 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting CAF1A PF12253.8 EJP68609.1 - 8.6e-23 80.3 3.5 8.6e-23 80.3 3.5 3.5 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Cwf_Cwc_15 PF04889.12 EJP68609.1 - 0.14 11.8 41.4 0.096 12.4 3.1 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CNDH2_C PF16858.5 EJP68609.1 - 0.8 9.5 26.6 2.4 8.0 0.4 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Raftlin PF15250.6 EJP68609.1 - 5.4 5.7 18.0 0.55 8.9 12.9 2.0 2 0 0 2 2 2 0 Raftlin V_ATPase_I PF01496.19 EJP68609.1 - 7 4.4 14.2 12 3.7 14.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Asp-B-Hydro_N PF05279.11 EJP68609.1 - 9.5 6.2 36.6 0.34 10.9 28.9 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Cu-oxidase_3 PF07732.15 EJP68611.1 - 4.1e-40 136.5 1.0 4.1e-40 136.5 1.0 3.7 4 1 1 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP68611.1 - 2.6e-39 134.1 9.2 1e-37 128.9 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EJP68611.1 - 6e-37 127.2 2.9 1.7e-36 125.7 0.7 2.7 2 1 1 3 3 3 1 Multicopper oxidase FAM219A PF15260.6 EJP68612.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein family FAM219A LepB_N PF18640.1 EJP68613.1 - 0.0096 15.6 0.0 0.063 12.9 0.0 1.9 2 0 0 2 2 2 1 LepB N-terminal domain Ank_2 PF12796.7 EJP68614.1 - 9.1e-19 67.8 0.0 3.8e-08 33.8 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP68614.1 - 2.3e-15 56.8 0.1 0.00038 21.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP68614.1 - 9.7e-11 41.7 0.5 0.07 13.5 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP68614.1 - 2.2e-09 36.7 3.1 0.52 11.0 0.0 7.5 9 0 0 9 9 9 2 Ankyrin repeat Ank PF00023.30 EJP68614.1 - 0.00046 20.5 1.2 1.5 9.4 0.0 5.2 6 0 0 6 6 6 1 Ankyrin repeat Ank_2 PF12796.7 EJP68615.1 - 4.8e-18 65.5 0.0 1.3e-08 35.3 0.0 4.2 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJP68615.1 - 6.2e-14 50.8 1.9 0.057 14.0 0.0 7.2 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 EJP68615.1 - 4.5e-10 39.9 2.2 0.14 12.8 0.0 6.1 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP68615.1 - 2.6e-09 37.2 2.4 0.14 12.5 0.0 6.3 4 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 EJP68615.1 - 0.00015 22.0 0.6 0.11 13.0 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat NinF PF05810.12 EJP68615.1 - 0.06 13.2 0.5 4 7.4 0.1 2.8 2 0 0 2 2 2 0 NinF protein MARVEL PF01284.23 EJP68617.1 - 2.6e-05 24.3 5.6 2.6e-05 24.3 5.6 2.1 1 1 1 2 2 2 1 Membrane-associating domain VIT1 PF01988.19 EJP68617.1 - 0.044 13.7 4.1 0.029 14.3 2.9 1.3 1 1 0 1 1 1 0 VIT family TMEM192 PF14802.6 EJP68617.1 - 0.2 10.7 1.2 0.33 10.0 0.4 1.6 1 1 0 1 1 1 0 TMEM192 family GWT1 PF06423.12 EJP68617.1 - 0.39 10.8 2.6 1.2 9.2 2.6 1.7 1 1 0 1 1 1 0 GWT1 DHHC PF01529.20 EJP68617.1 - 1.3 9.1 4.3 5.7 7.1 2.9 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase ABC2_membrane_3 PF12698.7 EJP68617.1 - 2.5 7.1 8.6 3.3 6.7 8.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Bot1p PF12298.8 EJP68618.1 - 3.8e-39 134.6 0.0 6.2e-39 133.9 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein HTH_Tnp_ISL3 PF13542.6 EJP68618.1 - 0.071 12.5 0.2 0.21 11.0 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Response_reg PF00072.24 EJP68619.1 - 1.9e-22 79.6 0.0 3.8e-16 59.2 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain SRR1 PF07985.12 EJP68620.1 - 5.5e-13 48.7 0.5 1.2e-12 47.7 0.0 1.7 2 0 0 2 2 2 1 SRR1 DUF2052 PF09747.9 EJP68621.1 - 4.4e-23 82.5 9.0 7.4e-12 45.8 2.4 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Lipase_3 PF01764.25 EJP68622.1 - 1.1e-16 61.0 0.0 1.7e-15 57.1 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) Acetyltransf_1 PF00583.25 EJP68623.1 - 9.7e-11 41.9 0.0 1.3e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP68623.1 - 1.2e-07 32.1 0.1 1.7e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP68623.1 - 1.7e-06 28.0 0.1 2.4e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Putative_PNPOx PF01243.20 EJP68624.1 - 0.0014 18.7 0.0 0.0038 17.4 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase VEGFR-2_TMD PF17988.1 EJP68624.1 - 0.13 11.7 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain HET PF06985.11 EJP68626.1 - 4.7e-06 27.0 0.0 9.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fer4_10 PF13237.6 EJP68626.1 - 0.05 13.7 0.5 1.4 9.1 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EJP68626.1 - 0.74 10.0 4.9 0.41 10.8 2.1 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain GLEYA PF10528.9 EJP68627.1 - 8.4e-17 61.4 0.4 1.5e-16 60.6 0.4 1.4 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 EJP68627.1 - 9.1e-06 25.5 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PA14 domain AMP-binding PF00501.28 EJP68628.1 - 2.7e-142 474.3 0.0 3e-72 243.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EJP68628.1 - 5.1e-129 430.9 0.0 3.3e-80 270.0 0.1 4.3 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EJP68628.1 - 7.7e-36 122.3 2.9 2.1e-11 44.0 0.0 4.1 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP68628.1 - 2.6e-14 54.0 6.5 0.0013 19.7 0.0 4.5 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 EJP68628.1 - 1.8e-05 25.4 0.0 0.00011 22.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP68628.1 - 0.00022 21.8 0.0 0.0011 19.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP68628.1 - 0.00039 21.1 0.0 0.0012 19.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP68628.1 - 0.0013 18.6 0.0 0.0049 16.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PIR PF00399.19 EJP68629.1 - 1.7e-05 24.2 6.7 1.7e-05 24.2 6.7 2.4 2 0 0 2 2 2 1 Yeast PIR protein repeat BDV_P10 PF06515.11 EJP68629.1 - 2.6 8.2 10.8 0.51 10.4 1.4 2.4 1 1 1 2 2 2 0 Borna disease virus P10 protein p450 PF00067.22 EJP68630.1 - 1.1e-71 241.9 0.0 1.5e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 EJP68631.1 - 9.4e-23 81.2 0.7 1.5e-22 80.5 0.7 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP68631.1 - 2.3e-11 43.2 0.0 3.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EJP68631.1 - 0.00057 19.2 0.1 0.024 13.9 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Zn_clus PF00172.18 EJP68632.1 - 4.8e-09 36.2 8.7 4.8e-09 36.2 8.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP68632.1 - 0.00028 19.8 0.2 0.00049 19.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MMR_HSR1_Xtn PF16897.5 EJP68633.1 - 1.3e-34 118.4 1.7 5.6e-34 116.3 0.4 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EJP68633.1 - 3.4e-20 72.2 0.0 7.5e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EJP68633.1 - 9.7e-18 64.0 0.0 1.9e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EJP68633.1 - 5.2e-12 45.6 0.0 8.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EJP68633.1 - 0.0001 22.4 0.2 0.059 13.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MCM PF00493.23 EJP68633.1 - 0.043 12.9 0.1 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain MeaB PF03308.16 EJP68633.1 - 0.068 12.1 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Spo12 PF05032.12 EJP68634.1 - 2.7e-16 59.1 1.7 9.2e-16 57.5 1.7 2.0 1 0 0 1 1 1 1 Spo12 family nec1 PF10379.9 EJP68634.1 - 5.1 6.6 10.3 6 6.3 10.0 1.4 1 1 0 1 1 1 0 Virulence protein nec1 RAP1 PF07218.11 EJP68634.1 - 6.9 4.8 8.2 6.4 4.9 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Acyl-CoA_dh_1 PF00441.24 EJP68635.1 - 8.2e-29 100.8 0.1 1.4e-28 100.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EJP68635.1 - 7.9e-20 70.9 0.0 1.4e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EJP68635.1 - 1e-13 51.9 0.1 1.9e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EJP68635.1 - 9.8e-10 38.8 0.1 1.7e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ras PF00071.22 EJP68636.1 - 2.4e-56 189.8 0.0 2.8e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP68636.1 - 1.6e-32 112.2 0.0 2.3e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP68636.1 - 1.6e-13 50.5 0.0 1.9e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJP68636.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EJP68636.1 - 1.9e-06 27.4 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EJP68636.1 - 1.7e-05 24.4 0.1 0.0003 20.4 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EJP68636.1 - 0.001 18.8 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EJP68636.1 - 0.0018 18.2 0.1 0.03 14.2 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 EJP68636.1 - 0.0041 16.6 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EJP68636.1 - 0.0046 17.4 0.0 0.0083 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EJP68636.1 - 0.0052 16.5 0.1 0.0068 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 EJP68636.1 - 0.006 16.4 0.2 0.19 11.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EJP68636.1 - 0.0068 16.7 0.0 0.014 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EJP68636.1 - 0.0093 16.0 0.0 0.019 15.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EJP68636.1 - 0.026 14.0 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 EJP68636.1 - 0.032 13.8 0.0 0.099 12.2 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EJP68636.1 - 0.059 13.3 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 EJP68636.1 - 0.06 12.6 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.15 EJP68636.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NTPase MCM PF00493.23 EJP68636.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 EJP68636.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_14 PF13173.6 EJP68636.1 - 0.13 12.3 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EJP68636.1 - 0.16 12.5 0.2 0.17 12.4 0.2 1.5 1 1 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 EJP68636.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_21 PF13304.6 EJP68636.1 - 0.18 11.6 0.8 5.2 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_lid_2 PF17863.1 EJP68637.1 - 5.9e-05 22.8 0.2 0.00014 21.6 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain GDA1_CD39 PF01150.17 EJP68638.1 - 1.7e-106 356.4 0.0 2.2e-106 356.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family FAM70 PF14967.6 EJP68638.1 - 5.6 6.3 5.9 9.8 5.5 5.9 1.3 1 0 0 1 1 1 0 FAM70 protein SAC3_GANP PF03399.16 EJP68639.1 - 1.2e-88 297.4 0.0 1.7e-88 296.8 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family LTV PF04180.14 EJP68640.1 - 3.1e-125 418.9 6.6 3.5e-125 418.7 6.6 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 EJP68641.1 - 3.1e-17 62.7 0.4 4.4e-15 55.8 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJP68641.1 - 4.4e-08 32.8 0.3 1.8e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EJP68641.1 - 1.5e-07 31.5 0.5 0.0073 16.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EJP68641.1 - 0.027 14.5 5.2 0.21 11.6 0.1 3.1 3 0 0 3 3 3 0 Dynamin family AIG1 PF04548.16 EJP68641.1 - 0.04 13.2 0.1 0.083 12.2 0.1 1.5 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 EJP68641.1 - 0.14 11.8 0.3 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF5523 PF17661.1 EJP68641.1 - 0.21 11.2 7.6 0.44 10.2 7.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Glyco_trans_2_3 PF13632.6 EJP68642.1 - 2.4e-49 167.9 6.1 2.4e-49 167.9 6.1 2.2 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EJP68642.1 - 6.6e-05 22.8 0.0 0.0032 17.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.21 EJP68643.1 - 2e-16 60.0 0.0 1.2e-15 57.5 0.0 2.2 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 DUF3974 PF13120.6 EJP68643.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) GAS2 PF02187.17 EJP68644.1 - 4e-07 30.0 0.0 9.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Fungal_trans PF04082.18 EJP68645.1 - 9.4e-33 113.4 2.3 9.6e-33 113.3 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP68645.1 - 9.7e-08 32.0 9.6 1.8e-07 31.2 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinocilin PF15033.6 EJP68645.1 - 0.079 12.6 0.0 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Kinocilin protein Malic_M PF03949.15 EJP68646.1 - 1.9e-93 312.5 0.0 3.1e-93 311.8 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EJP68646.1 - 4.7e-72 241.6 0.0 7.6e-72 240.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TruB_N PF01509.18 EJP68648.1 - 8.4e-45 152.8 0.0 1.6e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EJP68648.1 - 0.00013 22.0 0.0 0.00032 20.8 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Podoplanin PF05808.11 EJP68649.1 - 0.0079 16.3 1.6 0.0096 16.0 0.0 1.9 2 0 0 2 2 2 1 Podoplanin Gram_pos_anchor PF00746.21 EJP68649.1 - 0.015 15.2 1.9 0.035 14.1 1.9 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif IBV_3B PF03622.13 EJP68649.1 - 0.032 14.3 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 IBV 3B protein DUF4381 PF14316.6 EJP68649.1 - 0.055 13.7 0.1 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM154 PF15102.6 EJP68649.1 - 1.3 9.0 0.0 1.3 9.0 0.0 2.2 3 0 0 3 3 3 0 TMEM154 protein family DKCLD PF08068.12 EJP68650.1 - 3.8e-34 116.5 0.4 1.3e-32 111.6 0.3 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EJP68650.1 - 9.7e-23 81.2 0.2 5e-20 72.4 0.2 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EJP68650.1 - 1.3e-21 76.5 0.6 2.4e-21 75.6 0.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EJP68650.1 - 6.8e-19 67.6 0.3 1.3e-18 66.7 0.3 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EJP68650.1 - 0.01 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain DUF4838 PF16126.5 EJP68650.1 - 0.089 12.2 0.2 0.16 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) CN_hydrolase PF00795.22 EJP68652.1 - 1.4e-18 67.2 0.0 9.3e-18 64.5 0.0 2.2 2 1 1 3 3 3 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 EJP68653.1 - 7.9e-17 61.4 0.0 5.2e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase SKG6 PF08693.10 EJP68654.1 - 0.027 13.9 1.2 0.088 12.2 1.2 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FAM163 PF15069.6 EJP68654.1 - 0.043 14.3 0.1 0.29 11.6 0.0 2.4 2 0 0 2 2 2 0 FAM163 family Mid2 PF04478.12 EJP68654.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor VSP PF03302.13 EJP68654.1 - 3.5 6.4 14.9 0.041 12.8 6.1 2.1 1 1 1 2 2 2 0 Giardia variant-specific surface protein DER1 PF04511.15 EJP68655.1 - 4.1e-23 82.3 4.4 4.8e-23 82.1 4.4 1.0 1 0 0 1 1 1 1 Der1-like family Rep_fac_C PF08542.11 EJP68657.1 - 3.4e-23 81.9 0.0 9.8e-23 80.4 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EJP68657.1 - 4.4e-12 46.1 0.0 3.9e-08 33.2 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EJP68657.1 - 2.2e-11 44.3 0.0 3.9e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EJP68657.1 - 4.3e-07 30.0 0.0 9.4e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP68657.1 - 3.3e-06 27.6 0.0 0.00026 21.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EJP68657.1 - 2e-05 24.4 0.0 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EJP68657.1 - 9.4e-05 22.7 0.1 0.1 12.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EJP68657.1 - 0.0001 22.1 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EJP68657.1 - 0.00023 21.0 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EJP68657.1 - 0.00048 20.1 0.0 0.00099 19.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain MeaB PF03308.16 EJP68657.1 - 0.0021 17.1 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 EJP68657.1 - 0.0031 16.9 0.1 0.029 13.8 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 EJP68657.1 - 0.0042 16.9 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EJP68657.1 - 0.006 16.9 0.0 0.019 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain TniB PF05621.11 EJP68657.1 - 0.0087 15.5 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 EJP68657.1 - 0.012 16.0 0.1 0.031 14.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.8 EJP68657.1 - 0.013 15.4 0.1 0.45 10.4 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III NTPase_1 PF03266.15 EJP68657.1 - 0.014 15.3 0.1 0.05 13.5 0.1 1.9 1 1 0 2 2 2 0 NTPase KTI12 PF08433.10 EJP68657.1 - 0.036 13.5 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 EJP68657.1 - 0.04 13.7 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EJP68657.1 - 0.045 13.5 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EJP68657.1 - 0.05 13.4 0.1 1.2 8.8 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EJP68657.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EJP68657.1 - 0.13 11.8 0.0 0.66 9.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EJP68657.1 - 0.16 12.0 0.2 0.7 9.9 0.1 2.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Fcf1 PF04900.12 EJP68658.1 - 5.7e-35 119.7 0.1 1.1e-34 118.8 0.1 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EJP68658.1 - 2e-13 50.7 0.1 4.4e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 PIN like domain GCV_T PF01571.21 EJP68658.1 - 0.048 13.0 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF4706 PF15797.5 EJP68658.1 - 0.095 13.2 0.1 0.67 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) APH PF01636.23 EJP68660.1 - 1.6e-15 57.7 0.0 5e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 EJP68660.1 - 1.5e-09 37.3 0.5 2.5e-09 36.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP68660.1 - 4.4e-06 26.7 12.5 7.5e-06 26.0 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Choline_kinase PF01633.20 EJP68660.1 - 0.0043 16.7 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase ApbA PF02558.16 EJP68661.1 - 5e-21 74.9 0.0 3.2e-19 69.1 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EJP68661.1 - 5.9e-21 75.0 0.0 8.8e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 EJP68662.1 - 5.2e-22 77.9 5.3 7.5e-22 77.4 5.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like LPP PF04728.13 EJP68662.1 - 0.028 14.8 0.5 0.041 14.3 0.5 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Rpr2 PF04032.16 EJP68663.1 - 2.7e-22 78.9 0.1 3.8e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain HNH_5 PF14279.6 EJP68663.1 - 0.14 12.1 0.1 0.29 11.0 0.1 1.6 1 1 0 1 1 1 0 HNH endonuclease DEAD PF00270.29 EJP68664.1 - 1.1e-38 132.7 0.0 2e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP68664.1 - 3.6e-25 88.5 0.3 1.3e-23 83.5 0.2 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP68664.1 - 4.2e-08 33.4 0.0 1e-07 32.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 EJP68664.1 - 0.0032 18.0 0.6 0.0092 16.5 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4844) Cyclin PF08613.11 EJP68665.1 - 3.7e-05 24.1 2.7 3.7e-05 24.1 2.7 2.3 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EJP68665.1 - 0.059 13.1 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 Cyclin, N-terminal domain VP4_helical PF17478.2 EJP68665.1 - 4.4 6.7 11.2 2.4 7.5 3.9 2.2 2 0 0 2 2 2 0 Rotavirus VP4 helical domain Pyr_redox_2 PF07992.14 EJP68666.1 - 9.2e-08 31.7 0.3 3e-06 26.7 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP68666.1 - 0.00056 19.6 1.6 0.015 14.9 1.8 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EJP68666.1 - 0.00067 19.7 0.1 0.0078 16.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding ThiF PF00899.21 EJP68666.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 ThiF family RicinB_lectin_2 PF14200.6 EJP68668.1 - 3.9e-19 69.2 3.0 2.4e-10 41.0 0.1 2.9 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Bac_rhamnosid6H PF17389.2 EJP68668.1 - 4e-06 26.3 2.7 7.8e-06 25.4 2.7 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Ricin_B_lectin PF00652.22 EJP68668.1 - 0.0003 21.0 0.1 0.00079 19.7 0.1 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Trehalase PF01204.18 EJP68668.1 - 0.00075 18.4 0.1 0.0015 17.4 0.1 1.4 1 0 0 1 1 1 1 Trehalase tRNA-synt_1c PF00749.21 EJP68668.1 - 0.026 13.4 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Proteasome PF00227.26 EJP68669.1 - 1.5e-31 109.4 0.0 9.9e-31 106.7 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit GluRS_N PF18466.1 EJP68669.1 - 2.2 8.7 6.0 0.76 10.2 2.6 1.9 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain WD40 PF00400.32 EJP68670.1 - 1.5e-22 79.5 1.3 1.6e-05 25.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat WD40_like PF17005.5 EJP68670.1 - 0.0027 17.1 0.0 0.045 13.1 0.0 2.6 3 1 0 4 4 4 1 WD40-like domain ANAPC4_WD40 PF12894.7 EJP68670.1 - 0.003 17.8 0.0 0.4 11.0 0.0 3.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Red1 PF07964.11 EJP68670.1 - 0.46 8.7 6.5 0.77 7.9 6.5 1.3 1 0 0 1 1 1 0 Rec10 / Red1 Nha1_C PF08619.10 EJP68670.1 - 2 7.5 21.0 0.38 9.9 16.2 2.0 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Peptidase_C48 PF02902.19 EJP68671.1 - 7e-35 120.8 0.0 1.7e-34 119.6 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SPC22 PF04573.12 EJP68672.1 - 2.6e-40 137.7 0.4 3.5e-39 134.0 0.4 2.0 1 1 0 1 1 1 1 Signal peptidase subunit XRN_M PF17846.1 EJP68673.1 - 4.8e-100 335.6 5.4 9.4e-100 334.6 5.4 1.5 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EJP68673.1 - 2.3e-96 321.9 0.0 4.6e-96 320.9 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EJP68673.1 - 2.9e-67 226.2 0.0 7.1e-67 224.9 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EJP68673.1 - 1.9e-35 120.9 0.0 6.4e-35 119.2 0.0 2.0 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EJP68673.1 - 7.1e-19 67.7 0.0 1.5e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EJP68673.1 - 1.7e-05 24.8 0.1 4.1e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DUF2533 PF10752.9 EJP68673.1 - 0.01 16.3 0.2 0.038 14.4 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) CaATP_NAI PF12515.8 EJP68673.1 - 0.098 12.3 1.4 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain WD40 PF00400.32 EJP68674.1 - 9.3e-27 92.8 3.4 2.9e-07 31.1 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EJP68674.1 - 3.2e-26 91.4 0.1 1.9e-25 88.9 0.1 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EJP68674.1 - 1.7e-05 25.0 1.0 0.024 14.9 0.1 4.2 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Leader_Erm PF08253.11 EJP68674.1 - 0.69 10.3 2.0 9.9 6.7 0.4 2.7 3 0 0 3 3 3 0 Erm Leader peptide RHS_repeat PF05593.14 EJP68675.1 - 0.045 14.3 1.0 0.13 12.8 0.7 1.9 2 0 0 2 2 2 0 RHS Repeat zf-RanBP PF00641.18 EJP68676.1 - 3.3e-18 64.7 13.9 6e-11 41.5 1.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EJP68676.1 - 2.1e-08 33.9 0.0 6.2e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 EJP68676.1 - 0.0061 17.1 0.0 0.0099 16.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Pmp3 PF01679.17 EJP68677.1 - 3.2e-19 68.9 8.3 4.1e-19 68.5 8.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator FAT PF02259.23 EJP68679.1 - 1.1e-74 251.7 4.6 2.3e-74 250.7 4.6 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EJP68679.1 - 1.8e-33 116.4 0.0 5.4e-33 114.9 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EJP68679.1 - 1.2e-06 28.2 0.4 3.3e-06 26.8 0.4 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 EJP68679.1 - 0.033 14.3 2.6 0.7 10.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Urb2 PF10441.9 EJP68679.1 - 0.086 12.8 4.2 10 6.0 1.4 4.2 2 1 0 2 2 2 0 Urb2/Npa2 family TPR_1 PF00515.28 EJP68679.1 - 0.43 10.5 2.9 3.7 7.5 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJP68679.1 - 5.5 7.5 6.2 1.6 9.1 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HopW1-1 PF15457.6 EJP68681.1 - 0.009 15.3 0.3 0.015 14.6 0.3 1.3 1 0 0 1 1 1 1 Type III T3SS secreted effector HopW1-1/HopPmaA AMP-binding PF00501.28 EJP68682.1 - 8.8e-41 139.9 0.0 1.3e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EJP68682.1 - 3.9e-07 29.9 0.3 1.1e-06 28.4 0.3 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EJP68682.1 - 0.00065 20.6 0.1 0.0015 19.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1757 PF08560.10 EJP68683.1 - 0.00016 21.7 0.0 0.00025 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) TPR_2 PF07719.17 EJP68684.1 - 2.4e-30 102.2 20.4 0.00075 19.4 0.2 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP68684.1 - 3e-28 97.8 15.2 2.7e-23 82.0 0.8 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EJP68684.1 - 5e-25 86.2 15.7 0.00012 21.7 0.4 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 EJP68684.1 - 1.6e-22 79.8 15.5 0.0013 19.2 0.0 7.7 5 2 3 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 EJP68684.1 - 2.2e-18 64.9 3.6 0.016 15.4 0.1 9.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EJP68684.1 - 2.8e-16 59.5 20.3 2.1e-07 31.1 0.1 8.5 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJP68684.1 - 6.7e-16 58.7 20.6 2.1e-06 28.2 0.1 8.2 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EJP68684.1 - 7.9e-16 57.4 24.0 0.057 14.3 0.1 10.2 7 3 3 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 EJP68684.1 - 5.1e-10 38.9 13.3 0.02 14.8 0.1 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP68684.1 - 1.4e-07 31.0 18.9 0.2 11.8 0.1 9.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJP68684.1 - 4.8e-07 29.8 7.9 0.016 15.4 0.3 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJP68684.1 - 1.1e-05 25.1 11.2 2.5 7.8 0.0 7.2 8 1 1 9 9 9 3 TPR repeat TPR_21 PF09976.9 EJP68684.1 - 0.0005 19.8 8.9 0.21 11.3 0.8 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EJP68684.1 - 0.0011 19.4 18.3 0.94 10.3 0.1 8.8 11 0 0 11 11 8 1 Tetratricopeptide repeat TPR_5 PF12688.7 EJP68684.1 - 0.0018 18.5 0.6 0.0095 16.2 0.0 2.5 2 0 0 2 2 1 1 Tetratrico peptide repeat PPR PF01535.20 EJP68684.1 - 0.043 14.1 0.3 28 5.2 0.0 4.4 3 0 0 3 3 3 0 PPR repeat SRP_TPR_like PF17004.5 EJP68684.1 - 0.045 13.8 3.9 24 5.0 0.0 4.8 4 2 1 5 5 5 0 Putative TPR-like repeat TPR_17 PF13431.6 EJP68684.1 - 0.091 13.2 5.2 24 5.6 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TEX29 PF15839.5 EJP68684.1 - 0.38 11.4 1.3 13 6.4 0.2 2.5 1 1 1 2 2 2 0 Testis-expressed sequence 29 protein TPR_4 PF07721.14 EJP68684.1 - 5.5 7.9 18.8 2.7 8.9 0.1 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat F-box-like PF12937.7 EJP68685.1 - 6.1e-06 26.0 0.2 9e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 EJP68685.1 - 0.077 13.1 2.5 0.83 9.9 0.2 3.5 4 0 0 4 4 4 0 Leucine Rich repeat IGPD PF00475.18 EJP68686.1 - 2.8e-59 199.5 1.2 3.8e-59 199.1 1.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase IF-2B PF01008.17 EJP68687.1 - 3.8e-48 164.1 0.4 9.8e-48 162.8 0.4 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family TAF4 PF05236.14 EJP68687.1 - 5.5 6.7 8.0 8.2 6.1 8.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF3684 PF12449.8 EJP68689.1 - 0 1431.7 0.0 0 1431.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EJP68689.1 - 3.6e-05 23.6 0.0 0.00013 21.8 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.6 EJP68689.1 - 0.0068 16.6 2.6 0.0068 16.6 2.6 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Aldo_ket_red PF00248.21 EJP68690.1 - 5.3e-42 144.0 0.0 6.5e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MMtag PF10159.9 EJP68691.1 - 3.6e-31 107.3 3.0 3.6e-31 107.3 3.0 3.2 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Ribosomal_60s PF00428.19 EJP68691.1 - 2.7 8.7 9.0 0.8 10.3 2.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Med6 PF04934.14 EJP68692.1 - 6.5e-39 132.8 0.0 8.4e-39 132.4 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component adh_short_C2 PF13561.6 EJP68693.1 - 2e-50 171.6 0.1 2.6e-50 171.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP68693.1 - 1.6e-43 148.4 0.0 2e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP68693.1 - 7e-09 35.8 0.1 1.9e-08 34.4 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP68693.1 - 0.00095 18.7 0.4 0.011 15.1 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EJP68693.1 - 0.044 12.9 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HA2 PF04408.23 EJP68694.1 - 1.7e-24 86.2 0.0 1.7e-24 86.2 0.0 3.0 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EJP68694.1 - 6.6e-12 45.8 0.1 3.1e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EJP68694.1 - 3.2e-11 43.4 0.0 6.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EJP68694.1 - 3.9e-08 33.2 0.3 1e-07 31.9 0.3 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJP68694.1 - 1.5e-05 25.3 0.0 5.2e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP68694.1 - 0.00034 20.4 0.1 0.00087 19.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP68694.1 - 0.00037 20.8 0.1 0.00094 19.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EJP68694.1 - 0.0024 17.0 0.1 0.0082 15.2 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 EJP68694.1 - 0.0051 17.3 0.0 0.0051 17.3 0.0 3.8 4 0 0 4 4 4 1 AAA domain ATPase PF06745.13 EJP68694.1 - 0.026 13.9 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 EJP68694.1 - 0.028 14.4 1.4 4.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 EJP68694.1 - 0.029 13.7 1.2 0.071 12.4 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.16 EJP68694.1 - 0.03 13.8 0.0 0.085 12.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Zip PF02535.22 EJP68694.1 - 3.2 6.9 3.9 7.4 5.7 3.9 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter PAC3 PF10178.9 EJP68695.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 PAC4 PF16093.5 EJP68695.1 - 0.089 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Amelotin PF15757.5 EJP68695.1 - 0.12 11.9 1.9 0.85 9.2 0.0 2.0 1 1 1 2 2 2 0 Amelotin p450 PF00067.22 EJP68696.1 - 6.5e-79 265.8 0.0 7.6e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF485 PF04341.12 EJP68696.1 - 0.1 12.5 2.6 0.23 11.4 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF485 BCS1_N PF08740.11 EJP68697.1 - 1.1e-28 100.4 0.0 1.9e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EJP68697.1 - 7.7e-21 74.9 0.0 1.6e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EJP68697.1 - 0.005 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP68697.1 - 0.016 15.6 0.2 0.074 13.4 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain ATPase PF06745.13 EJP68697.1 - 0.03 13.7 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.11 EJP68697.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EJP68697.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Aegerolysin PF06355.13 EJP68699.1 - 8.2e-36 123.0 0.1 9.1e-36 122.8 0.1 1.0 1 0 0 1 1 1 1 Aegerolysin CsoS2_M PF12288.8 EJP68699.1 - 0.072 12.5 0.1 0.088 12.2 0.1 1.1 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region FAD_binding_3 PF01494.19 EJP68700.1 - 3.3e-18 66.1 0.3 1.3e-10 41.0 0.0 2.5 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.24 EJP68700.1 - 5.3e-10 39.4 4.0 2.4e-06 27.4 1.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJP68700.1 - 9e-07 28.3 3.1 0.0042 16.2 1.3 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 EJP68700.1 - 1.7e-06 28.2 0.6 8.5e-06 25.9 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP68700.1 - 4.4e-06 26.2 0.1 1.2e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EJP68700.1 - 1.1e-05 24.5 0.6 0.016 14.1 0.1 2.3 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 EJP68700.1 - 0.00019 20.7 0.9 0.00019 20.7 0.9 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EJP68700.1 - 0.00079 18.7 0.2 0.0016 17.8 0.2 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 EJP68700.1 - 0.043 13.0 0.1 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) EPO_TPO PF00758.18 EJP68700.1 - 0.06 13.4 0.1 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin HI0933_like PF03486.14 EJP68700.1 - 0.064 11.9 0.7 0.11 11.1 0.3 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 EJP68700.1 - 0.065 12.5 0.4 0.097 11.9 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP68700.1 - 0.089 12.8 3.8 0.15 12.1 0.4 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EJP68700.1 - 0.09 13.4 0.3 0.5 10.9 0.2 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP68700.1 - 0.2 10.7 0.5 0.3 10.1 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 EJP68700.1 - 0.2 11.3 0.2 0.34 10.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Metallophos PF00149.28 EJP68701.1 - 2.2e-37 129.6 0.2 4.8e-37 128.5 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TauD PF02668.16 EJP68702.1 - 6.5e-36 124.5 0.1 9.3e-36 124.0 0.1 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EJP68702.1 - 4.1e-10 40.2 0.3 8.7e-10 39.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EJP68702.1 - 0.028 13.6 0.0 0.06 12.5 0.0 1.5 2 0 0 2 2 2 0 CsiD UCH PF00443.29 EJP68703.1 - 8.9e-31 107.3 0.0 5.1e-28 98.3 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJP68703.1 - 4.2e-07 29.9 0.0 9.8e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPT PF03151.16 EJP68704.1 - 1.6e-25 90.1 24.0 1.9e-25 89.8 24.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EJP68704.1 - 0.0006 19.1 23.0 0.00085 18.6 23.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EJP68704.1 - 1.1 9.4 47.6 0.34 11.1 14.8 2.5 3 0 0 3 3 3 0 EamA-like transporter family CVNH PF08881.10 EJP68705.1 - 1.3e-05 25.8 0.0 1.8e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 CVNH domain COMPASS-Shg1 PF05205.12 EJP68706.1 - 3.6e-24 85.4 0.2 3.6e-24 85.4 0.2 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 Tom5 PF10642.9 EJP68706.1 - 3 8.0 4.4 0.81 9.8 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Hexapep PF00132.24 EJP68707.1 - 2.1e-12 46.2 11.0 3.4e-09 36.0 4.2 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EJP68707.1 - 3.9e-11 42.5 8.5 1.8e-08 34.0 3.8 2.5 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EJP68707.1 - 1.6e-07 31.5 0.3 2.8e-07 30.7 0.3 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase tRNA_bind_3 PF17176.4 EJP68707.1 - 0.032 14.5 0.1 0.046 14.0 0.1 1.2 1 0 0 1 1 1 0 tRNA-binding domain PEP-utilisers_N PF05524.13 EJP68707.1 - 0.22 11.7 1.0 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF2613 PF11021.8 EJP68707.1 - 0.45 10.7 4.0 0.4 10.8 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Mito_carr PF00153.27 EJP68708.1 - 1.4e-15 56.9 3.9 1.5e-05 24.8 0.1 5.1 3 2 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M43 PF05572.13 EJP68709.1 - 1.2e-16 61.0 0.2 4.3e-16 59.2 0.0 2.0 3 0 0 3 3 3 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EJP68709.1 - 0.0076 16.4 1.6 0.022 14.9 1.4 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EJP68709.1 - 0.066 13.7 0.9 0.51 10.9 0.0 2.3 2 1 1 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EJP68709.1 - 0.15 10.9 2.3 0.11 11.5 0.3 1.6 2 0 0 2 2 2 0 Peptidase M66 Fer2 PF00111.27 EJP68710.1 - 1.4e-11 44.2 1.4 2.2e-11 43.5 1.4 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.12 EJP68711.1 - 3e-36 124.7 8.2 3e-36 124.7 8.2 2.5 2 1 0 2 2 2 1 Rrp15p PhoD PF09423.10 EJP68712.1 - 2.8e-42 145.0 0.0 5.8e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase FAD_binding_3 PF01494.19 EJP68712.1 - 1.4e-23 83.7 0.6 2.1e-23 83.1 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EJP68712.1 - 0.00041 19.7 0.8 0.033 13.4 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP68712.1 - 0.00053 19.7 1.0 0.0072 16.0 0.1 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase ApbA PF02558.16 EJP68712.1 - 0.0022 17.7 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 EJP68712.1 - 0.022 15.0 0.0 0.079 13.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP68712.1 - 0.08 13.5 1.2 0.15 12.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EJP68712.1 - 0.082 11.7 1.3 3.2 6.5 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 EJP68712.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1932 PF09130.11 EJP68713.1 - 1.9e-21 75.8 0.5 4.1e-21 74.7 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 EJP68713.1 - 9.2e-07 29.4 0.0 2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EJP68713.1 - 2.9e-05 24.3 0.0 6.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EJP68713.1 - 0.00046 19.6 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EJP68713.1 - 0.019 14.8 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SSTK-IP PF15836.5 EJP68713.1 - 0.083 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Pkinase PF00069.25 EJP68714.1 - 1.8e-08 34.1 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EJP68714.1 - 0.00053 20.0 0.2 0.00076 19.5 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EJP68714.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EMP24_GP25L PF01105.24 EJP68715.1 - 4.2e-47 160.4 2.4 4.8e-47 160.3 2.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SKIP_SNW PF02731.15 EJP68716.1 - 6.9e-69 230.6 7.3 6.9e-69 230.6 7.3 2.3 2 0 0 2 2 2 1 SKIP/SNW domain DUF3139 PF11337.8 EJP68718.1 - 0.014 16.0 0.4 0.026 15.1 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Synaptobrevin PF00957.21 EJP68718.1 - 0.091 12.6 1.6 0.15 11.9 1.6 1.2 1 0 0 1 1 1 0 Synaptobrevin DUF4307 PF14155.6 EJP68718.1 - 0.61 9.9 3.6 0.57 10.0 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) PGP_phosphatase PF09419.10 EJP68719.1 - 4e-62 208.7 0.0 5.3e-62 208.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Tim17 PF02466.19 EJP68719.1 - 1.2e-38 131.9 4.3 1.2e-38 131.9 4.3 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Hydrolase_like PF13242.6 EJP68719.1 - 0.0045 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF543 PF04418.12 EJP68719.1 - 0.15 12.1 1.1 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Zn_clus PF00172.18 EJP68720.1 - 0.16 12.1 11.5 0.82 9.8 11.5 2.1 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 EJP68721.1 - 1.8e-06 26.8 0.1 3.4e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family MOSC PF03473.17 EJP68722.1 - 2.5e-21 76.0 0.0 9.9e-21 74.1 0.0 1.8 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 EJP68722.1 - 1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain ARTD15_N PF18084.1 EJP68722.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 ARTD15 N-terminal domain adh_short PF00106.25 EJP68723.1 - 3.2e-20 72.4 0.0 2.9e-19 69.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP68723.1 - 4e-14 52.7 0.0 2e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Insulin_TMD PF17870.1 EJP68724.1 - 0.048 13.7 0.7 0.073 13.1 0.7 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pro_Al_protease PF02983.14 EJP68725.1 - 1.6e-08 34.5 1.6 6.9e-08 32.4 0.0 2.8 2 1 0 2 2 2 1 Alpha-lytic protease prodomain Trypsin PF00089.26 EJP68725.1 - 4.5e-06 26.6 11.7 1.4e-05 25.1 11.7 1.8 1 1 0 1 1 1 1 Trypsin Secretin_N PF03958.17 EJP68725.1 - 0.0051 17.2 4.4 0.019 15.3 4.4 2.1 1 1 0 1 1 1 1 Bacterial type II/III secretion system short domain DUF4096 PF13340.6 EJP68726.1 - 0.093 13.0 0.4 0.32 11.2 0.4 1.9 1 1 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) ORC2 PF04084.14 EJP68727.1 - 2.3e-115 385.0 0.0 3.3e-115 384.5 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 MSP1_C PF07462.11 EJP68727.1 - 1.8 7.1 4.4 2.8 6.5 4.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Sensor PF13796.6 EJP68729.1 - 0.047 13.8 0.0 0.047 13.8 0.0 1.7 2 0 0 2 2 2 0 Putative sensor DUF1754 PF08555.10 EJP68730.1 - 2.7e-12 47.3 17.8 4.6e-12 46.6 17.8 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 EJP68730.1 - 0.05 13.0 17.8 0.056 12.8 17.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AA_permease_2 PF13520.6 EJP68731.1 - 9.8e-66 222.3 33.1 1.3e-65 222.0 33.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP68731.1 - 3.2e-24 85.4 26.1 3.2e-24 85.4 26.1 2.1 2 0 0 2 2 2 1 Amino acid permease PSII PF00421.19 EJP68731.1 - 0.015 14.0 1.5 0.025 13.2 1.5 1.3 1 0 0 1 1 1 0 Photosystem II protein 2-Hacid_dh_C PF02826.19 EJP68732.1 - 9.7e-52 174.9 0.0 1.9e-51 174.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJP68732.1 - 5.5e-16 58.4 0.0 7.9e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EJP68732.1 - 0.00041 20.6 0.0 0.00097 19.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PROCN PF08083.11 EJP68732.1 - 0.18 10.5 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain F-box PF00646.33 EJP68733.1 - 0.029 14.3 0.3 0.069 13.0 0.3 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EJP68733.1 - 0.11 12.4 0.5 0.31 11.0 0.5 1.7 1 0 0 1 1 1 0 F-box-like Peptidase_M18 PF02127.15 EJP68735.1 - 5.1e-126 421.0 0.0 6.1e-126 420.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) EXS PF03124.14 EJP68736.1 - 2.1e-100 336.3 33.5 2.7e-100 335.9 33.5 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EJP68736.1 - 4.3e-84 283.7 2.2 4.3e-84 283.7 2.2 2.2 2 0 0 2 2 2 1 SPX domain SLT PF01464.20 EJP68737.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.7 2 1 0 2 2 2 0 Transglycosylase SLT domain Ank_2 PF12796.7 EJP68738.1 - 1.1e-14 54.7 0.4 4.4e-07 30.4 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJP68738.1 - 2.9e-10 40.2 0.1 0.00015 22.0 0.0 4.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP68738.1 - 3.2e-08 33.2 4.5 0.064 13.8 0.0 6.2 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 EJP68738.1 - 7.2e-08 32.8 3.6 0.0094 16.5 0.9 3.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EJP68738.1 - 0.001 19.4 3.3 0.044 14.3 0.0 4.2 5 0 0 5 5 5 1 Ankyrin repeat F-box-like PF12937.7 EJP68738.1 - 0.016 15.1 0.0 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 F-box-like AA_permease_2 PF13520.6 EJP68739.1 - 5.2e-48 163.9 36.0 6.5e-48 163.6 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP68739.1 - 6.9e-24 84.3 26.8 9.6e-24 83.8 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease Strabismus PF06638.11 EJP68739.1 - 0.43 9.2 0.8 0.75 8.4 0.8 1.3 1 0 0 1 1 1 0 Strabismus protein DUF3278 PF11683.8 EJP68740.1 - 0.0087 16.2 0.5 0.0087 16.2 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3278) F-box PF00646.33 EJP68741.1 - 0.00096 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EJP68741.1 - 0.0055 16.6 0.0 0.017 15.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like CinA PF02464.17 EJP68741.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Competence-damaged protein LysM PF01476.20 EJP68742.1 - 7e-06 26.0 1.1 2.1 8.5 0.0 4.8 4 1 1 5 5 5 4 LysM domain OPT PF03169.15 EJP68744.1 - 2.7e-167 558.1 53.7 3.1e-167 557.9 53.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_16 PF00722.21 EJP68745.1 - 1.5e-08 34.3 0.1 2.2e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Prok-E2_E PF14462.6 EJP68745.1 - 0.07 12.9 0.4 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family E ABC2_membrane PF01061.24 EJP68746.1 - 8.6e-92 306.3 60.2 6.1e-47 159.8 23.8 3.3 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 EJP68746.1 - 1.2e-38 130.9 10.4 1.2e-34 118.1 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 EJP68746.1 - 2e-35 122.3 0.0 3.1e-16 60.1 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 EJP68746.1 - 4.6e-16 59.2 0.0 1.3e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EJP68746.1 - 9.5e-08 32.6 0.1 0.00067 20.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EJP68746.1 - 1.1e-06 28.7 0.1 0.00074 19.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EJP68746.1 - 3e-06 27.0 0.0 0.0003 20.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EJP68746.1 - 3.9e-06 26.9 0.0 0.5 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJP68746.1 - 6.7e-06 25.8 0.1 0.035 13.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EJP68746.1 - 7.6e-06 26.5 0.0 0.11 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EJP68746.1 - 0.00023 20.7 0.0 2.2 7.7 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 EJP68746.1 - 0.00028 20.1 11.5 0.00028 20.1 11.5 4.0 3 2 1 4 4 4 1 ABC-2 family transporter protein AAA_33 PF13671.6 EJP68746.1 - 0.00079 19.6 0.0 0.29 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EJP68746.1 - 0.0013 19.0 0.1 0.23 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EJP68746.1 - 0.0025 17.7 0.0 0.67 9.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 EJP68746.1 - 0.0033 18.0 0.0 0.17 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EJP68746.1 - 0.0043 17.3 0.0 4.7 7.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EJP68746.1 - 0.0096 15.0 0.0 0.091 11.8 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.19 EJP68746.1 - 0.011 15.3 0.3 0.64 9.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EJP68746.1 - 0.013 16.0 0.3 3.3 8.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EJP68746.1 - 0.019 15.4 0.0 4.2 7.8 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EJP68746.1 - 0.022 14.5 0.2 6.9 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EJP68746.1 - 0.055 13.5 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EJP68746.1 - 0.064 13.0 0.0 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 EJP68746.1 - 0.15 11.9 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Viral_helicase1 PF01443.18 EJP68746.1 - 0.16 11.7 0.1 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MFS_1 PF07690.16 EJP68747.1 - 6.9e-35 120.6 37.7 2.9e-32 112.0 18.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2754 PF10953.8 EJP68747.1 - 0.062 13.5 1.8 0.32 11.3 1.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) LIP PF03583.14 EJP68748.1 - 5.9e-11 42.2 2.6 0.0001 21.7 1.5 2.2 2 0 0 2 2 2 2 Secretory lipase Hydrolase_4 PF12146.8 EJP68748.1 - 3.7e-10 39.5 0.5 3.5e-09 36.3 0.5 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EJP68748.1 - 6.6e-08 32.3 0.8 7.4e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EJP68748.1 - 8.7e-07 29.8 1.2 1.7e-06 28.8 1.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EJP68748.1 - 9e-07 28.7 0.3 0.016 14.8 0.0 2.5 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EJP68748.1 - 0.00015 21.5 1.0 0.00015 21.5 1.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2722 PF10846.8 EJP68748.1 - 0.00064 18.8 0.3 0.00086 18.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DLH PF01738.18 EJP68748.1 - 0.0065 16.0 4.0 0.0086 15.6 0.0 2.7 2 1 1 3 3 3 1 Dienelactone hydrolase family Androgen_recep PF02166.16 EJP68748.1 - 0.042 12.7 11.7 0.072 11.9 11.7 1.3 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 EJP68748.1 - 0.87 9.5 10.9 0.2 11.6 7.1 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EJP68748.1 - 2.4 7.7 16.4 4.4 6.8 16.4 1.3 1 0 0 1 1 1 0 Spt20 family Gly_transf_sug PF04488.15 EJP68749.1 - 2.2e-07 31.4 0.0 5.9e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Defensin_2 PF01097.18 EJP68750.1 - 0.028 14.4 11.3 0.028 14.4 11.3 3.3 2 1 0 2 2 2 0 Arthropod defensin RRN3 PF05327.11 EJP68751.1 - 5.2e-175 583.2 0.3 5.2e-175 583.2 0.3 1.4 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 CBFD_NFYB_HMF PF00808.23 EJP68752.1 - 4.7e-30 103.7 0.9 6.3e-30 103.3 0.9 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EJP68752.1 - 4e-06 27.2 0.1 7.9e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EJP68752.1 - 0.00062 19.7 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EJP68752.1 - 0.0014 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EJP68752.1 - 0.0025 17.9 0.1 0.0033 17.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EJP68752.1 - 0.053 14.0 0.2 0.1 13.1 0.1 1.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 EJP68753.1 - 1.1e-23 83.1 8.3 1.3e-23 82.9 8.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit XFP_N PF09364.10 EJP68753.1 - 0.0084 14.9 0.1 0.01 14.7 0.1 1.0 1 0 0 1 1 1 1 XFP N-terminal domain Prefoldin PF02996.17 EJP68753.1 - 0.027 14.4 7.2 0.12 12.3 0.3 2.2 1 1 0 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.19 EJP68753.1 - 0.068 11.1 0.9 0.069 11.1 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lyase_8_N PF08124.11 EJP68753.1 - 0.089 11.7 1.2 4.6 6.1 0.2 2.0 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain FliE PF02049.18 EJP68753.1 - 0.2 11.8 3.6 0.41 10.8 0.9 2.0 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE HTH_57 PF18679.1 EJP68753.1 - 0.29 11.5 2.4 1.7 9.0 0.1 2.2 1 1 1 2 2 2 0 ThcOx helix turn helix domain DUF4795 PF16043.5 EJP68753.1 - 0.53 9.9 6.8 0.88 9.1 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF2205 PF10224.9 EJP68753.1 - 0.8 9.7 5.0 0.31 11.1 1.0 2.0 2 0 0 2 2 2 0 Short coiled-coil protein Cytochrom_B562 PF07361.11 EJP68753.1 - 1.3 9.7 5.6 1.4 9.6 1.3 2.1 2 0 0 2 2 2 0 Cytochrome b562 Cmc1 PF08583.10 EJP68754.1 - 4.1e-16 58.8 6.3 4.9e-16 58.5 6.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1110 PF06533.12 EJP68754.1 - 0.0089 16.0 1.8 0.012 15.6 1.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1110) DUF2390 PF09523.10 EJP68754.1 - 0.064 13.6 0.4 0.075 13.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DUF3128 PF11326.8 EJP68754.1 - 0.29 11.5 2.4 0.42 11.0 2.4 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Tmemb_14 PF03647.13 EJP68755.1 - 1.5e-23 83.4 6.2 1.9e-23 83.0 6.2 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 EJP68755.1 - 0.0046 17.2 2.4 0.1 12.9 2.4 2.5 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF2755 PF10954.8 EJP68755.1 - 0.13 12.2 0.2 1.9 8.5 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2755) DAD PF02109.16 EJP68756.1 - 7.4e-49 164.6 4.9 9.1e-49 164.3 4.9 1.1 1 0 0 1 1 1 1 DAD family GRASP55_65 PF04495.14 EJP68757.1 - 8.3e-42 142.8 0.0 3.7e-41 140.7 0.0 1.8 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EJP68757.1 - 0.019 14.8 0.0 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 PDZ domain Methyltransf_15 PF09445.10 EJP68758.1 - 8.8e-38 129.5 0.0 1.7e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DUF4110 PF13422.6 EJP68758.1 - 1.4e-30 105.2 1.5 1.4e-30 105.2 1.5 2.9 4 0 0 4 4 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 EJP68758.1 - 1.7e-26 91.9 8.8 5.1e-08 32.8 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EJP68758.1 - 3.3e-22 78.3 9.3 4.7e-06 26.8 0.0 6.3 6 0 0 6 6 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EJP68758.1 - 1.3e-17 63.4 1.2 6.9e-07 29.1 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EJP68758.1 - 2.7e-14 52.5 1.7 0.00036 20.4 0.1 5.6 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EJP68758.1 - 2.3e-13 49.9 2.1 0.00034 20.8 0.1 5.6 6 0 0 6 6 5 3 Kelch motif Kelch_1 PF01344.25 EJP68758.1 - 1.1e-10 40.9 0.6 0.0016 18.0 0.0 5.2 5 1 0 5 5 5 2 Kelch motif Methyltransf_5 PF01795.19 EJP68758.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family tRNA_U5-meth_tr PF05958.11 EJP68758.1 - 0.041 12.9 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 EJP68758.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EJP68758.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EJP68758.1 - 0.12 13.1 0.0 0.38 11.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain SR-25 PF10500.9 EJP68758.1 - 9.3 5.8 21.6 0.55 9.8 15.2 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_C15 PF01470.17 EJP68760.1 - 6e-11 42.9 0.0 0.00012 22.3 0.0 2.8 2 1 0 2 2 2 2 Pyroglutamyl peptidase HAD_2 PF13419.6 EJP68761.1 - 2.9e-19 69.8 0.0 3.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP68761.1 - 8.8e-10 39.2 0.0 4.2e-06 27.2 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP68761.1 - 1.9e-05 24.6 0.1 3.6e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EJP68761.1 - 3.8e-05 24.2 0.0 5.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.6 EJP68761.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Hepar_II_III_N PF16889.5 EJP68762.1 - 0.0065 15.8 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Heparinase II/III N-terminus MF_alpha_N PF05436.11 EJP68762.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus BCAS2 PF05700.11 EJP68763.1 - 1.5e-52 178.3 6.0 1.8e-52 178.1 6.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.8 EJP68763.1 - 0.0075 16.5 3.0 0.018 15.3 3.0 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 EJP68763.1 - 0.019 15.1 3.8 0.032 14.3 3.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 EJP68763.1 - 0.097 12.0 4.1 0.15 11.4 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) cNMP_binding PF00027.29 EJP68764.1 - 1.4e-37 127.7 0.0 4.3e-19 68.4 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain SAGA-Tad1 PF12767.7 EJP68765.1 - 5.2e-64 216.2 0.0 7e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GCP_C_terminal PF04130.13 EJP68766.1 - 2.6e-97 326.0 0.0 4.1e-97 325.4 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EJP68766.1 - 1.9e-83 280.6 0.0 2.9e-83 280.0 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Acetyltransf_1 PF00583.25 EJP68767.1 - 4.8e-10 39.7 0.0 6.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP68767.1 - 1.9e-08 34.3 0.0 2.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP68767.1 - 0.00052 20.4 0.0 0.00078 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CDT1_C PF16679.5 EJP68769.1 - 2.1e-23 82.6 4.7 1.3e-22 80.0 0.0 3.2 3 1 1 4 4 4 1 DNA replication factor Cdt1 C-terminal domain PRP1_N PF06424.12 EJP68769.1 - 6.7 7.1 11.8 1.3 9.4 6.9 2.1 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal MFS_1 PF07690.16 EJP68770.1 - 3e-37 128.4 30.4 3e-37 128.4 30.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68770.1 - 1.4e-07 30.8 14.3 1.4e-07 30.8 14.3 2.8 2 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EJP68770.1 - 0.00011 20.6 2.2 0.00032 19.1 2.2 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF3405 PF11885.8 EJP68771.1 - 2.2e-203 676.6 1.4 3.1e-202 672.8 1.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) SDA1 PF05285.12 EJP68771.1 - 4.2 6.7 19.9 6.3 6.1 19.9 1.2 1 0 0 1 1 1 0 SDA1 DUF4667 PF15700.5 EJP68771.1 - 6.4 6.8 9.5 11 6.1 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Rho_N PF07498.12 EJP68772.1 - 0.0013 18.7 1.9 0.0028 17.5 1.9 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain p450 PF00067.22 EJP68773.1 - 4.2e-09 35.7 0.0 1.2e-08 34.2 0.0 1.7 1 1 1 2 2 2 1 Cytochrome P450 FTHFS PF01268.19 EJP68774.1 - 3.2e-253 841.0 0.2 4.2e-253 840.6 0.2 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EJP68774.1 - 2.9e-67 225.0 1.5 2.9e-67 225.0 1.5 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EJP68774.1 - 2.1e-37 127.9 0.1 4e-37 127.0 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF3343 PF11823.8 EJP68774.1 - 0.16 11.4 0.0 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) AMP-binding PF00501.28 EJP68775.1 - 1.6e-59 201.6 0.0 2.4e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EJP68775.1 - 5.1e-27 94.7 0.0 6.9e-20 71.2 0.0 3.0 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EJP68775.1 - 3.5e-08 33.7 0.1 8.4e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EJP68775.1 - 0.0089 17.0 0.0 0.029 15.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sulfotransfer_4 PF17784.1 EJP68776.1 - 8.2e-60 202.3 0.1 9.9e-60 202.0 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EJP68776.1 - 0.0077 16.6 1.5 0.22 11.9 0.2 2.5 1 1 0 2 2 2 1 Sulfotransferase family AHJR-like PF18743.1 EJP68776.1 - 0.093 12.3 0.0 3.9 7.1 0.0 2.3 2 0 0 2 2 2 0 REase_AHJR-like HD PF01966.22 EJP68777.1 - 2.7e-06 27.6 0.1 6.7e-06 26.3 0.1 1.7 1 1 0 1 1 1 1 HD domain PDEase_I PF00233.19 EJP68777.1 - 0.022 14.5 0.5 0.043 13.5 0.5 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase HD_2 PF12917.7 EJP68777.1 - 0.041 13.6 1.3 0.1 12.3 1.3 1.8 1 1 0 1 1 1 0 HD containing hydrolase-like enzyme Aldo_ket_red PF00248.21 EJP68778.1 - 3e-32 112.0 0.0 4.7e-28 98.2 0.0 3.2 1 1 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.22 EJP68778.1 - 1.3e-14 55.0 0.0 4.2e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EJP68778.1 - 1.2e-05 25.2 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 EJP68778.1 - 0.019 15.7 0.0 0.05 14.3 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain 2OG-FeII_Oxy PF03171.20 EJP68779.1 - 5.8e-11 42.8 0.0 1.3e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EJP68779.1 - 1e-05 26.2 0.0 2.5e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Sulfotransfer_3 PF13469.6 EJP68780.1 - 0.00057 20.3 0.1 0.0052 17.2 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family Abhydrolase_4 PF08386.10 EJP68781.1 - 1e-18 67.3 0.1 2.6e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 EJP68781.1 - 1.8e-15 57.3 0.0 1.5e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase3_N PF03893.16 EJP68781.1 - 0.12 12.4 0.1 0.4 10.7 0.1 1.9 1 0 0 1 1 1 0 Lipase 3 N-terminal region WD40 PF00400.32 EJP68782.1 - 8.3e-23 80.2 1.5 1.9e-08 34.8 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP68782.1 - 5.6e-12 45.8 0.0 0.083 13.2 0.0 5.1 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP68782.1 - 0.0091 14.7 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EJP68782.1 - 0.023 14.0 0.0 0.21 10.9 0.0 2.2 1 1 0 2 2 2 0 WD40-like domain PQQ_2 PF13360.6 EJP68782.1 - 0.05 13.2 0.0 0.69 9.4 0.0 2.4 1 1 0 1 1 1 0 PQQ-like domain SNF2_N PF00176.23 EJP68783.1 - 4.2e-76 256.0 0.1 7.4e-76 255.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EJP68783.1 - 2.9e-42 143.3 2.3 9.5e-42 141.6 2.3 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 EJP68783.1 - 2.4e-36 124.8 5.4 2.4e-36 124.8 5.4 3.1 2 0 0 2 2 2 1 HAND Helicase_C PF00271.31 EJP68783.1 - 1.2e-18 67.5 0.1 5.7e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP68783.1 - 5e-11 42.9 0.0 2.8e-10 40.5 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EJP68783.1 - 5.5e-06 25.8 0.0 4.6e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 EJP68783.1 - 3.1e-05 24.1 0.0 0.047 13.9 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DEAD PF00270.29 EJP68783.1 - 0.00031 20.6 0.0 0.00079 19.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EJP68783.1 - 0.00081 19.1 0.0 0.0032 17.2 0.0 2.0 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EJP68783.1 - 0.0029 16.9 0.1 0.0029 16.9 0.1 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DUF1086 PF06461.11 EJP68783.1 - 0.044 13.6 0.3 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) DEAD_2 PF06733.15 EJP68783.1 - 0.092 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Atg14 PF10186.9 EJP68783.1 - 4.1 6.4 6.8 0.92 8.5 0.4 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4588 PF15251.6 EJP68784.1 - 1.1e-07 31.9 0.2 1.3e-07 31.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) bZIP_1 PF00170.21 EJP68784.1 - 0.026 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 bZIP transcription factor SPATA3 PF15662.5 EJP68784.1 - 7.9 7.1 9.5 0.75 10.4 4.2 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family Ion_trans PF00520.31 EJP68785.1 - 2.9e-06 26.7 1.1 4e-06 26.2 1.1 1.1 1 0 0 1 1 1 1 Ion transport protein FA_desaturase PF00487.24 EJP68785.1 - 0.0028 17.5 0.6 0.0042 16.9 0.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase BRE1 PF08647.11 EJP68785.1 - 0.026 14.6 0.3 0.039 14.0 0.3 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase SYCE1 PF15233.6 EJP68785.1 - 0.047 13.8 0.5 0.07 13.2 0.5 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 SUR7 PF06687.12 EJP68785.1 - 0.067 12.8 0.2 0.1 12.2 0.2 1.3 1 1 0 1 1 1 0 SUR7/PalI family CCDC106 PF15794.5 EJP68785.1 - 0.097 12.4 1.2 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 bZIP_1 PF00170.21 EJP68785.1 - 0.16 12.1 0.5 0.31 11.2 0.5 1.5 1 1 0 1 1 1 0 bZIP transcription factor RRM_1 PF00076.22 EJP68786.1 - 7.5e-16 57.7 0.0 1.1e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.12 EJP68786.1 - 0.022 15.2 0.2 0.042 14.3 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EJP68786.1 - 0.036 14.4 0.5 0.046 14.0 0.5 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup35_RRM_2 PF14605.6 EJP68786.1 - 0.038 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PRKG1_interact PF15898.5 EJP68786.1 - 0.043 14.7 3.9 0.061 14.2 3.9 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain RRM_occluded PF16842.5 EJP68786.1 - 0.069 13.0 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif V_ATPase_I PF01496.19 EJP68786.1 - 0.076 10.9 1.7 0.085 10.8 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GPS2_interact PF15784.5 EJP68786.1 - 0.084 13.3 2.9 0.14 12.6 2.9 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DivIC PF04977.15 EJP68786.1 - 0.19 11.5 5.0 0.3 10.9 5.0 1.3 1 0 0 1 1 1 0 Septum formation initiator EMP24_GP25L PF01105.24 EJP68786.1 - 0.2 11.6 0.7 0.28 11.1 0.7 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HECT PF00632.25 EJP68787.1 - 5e-93 311.9 0.0 7e-93 311.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EJP68787.1 - 2.3e-33 114.0 23.4 1.2e-11 44.4 5.1 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EJP68787.1 - 5.6e-18 65.1 0.0 1.6e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain Oxidored_q6 PF01058.22 EJP68788.1 - 3.7e-22 78.6 0.0 5.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Esterase PF00756.20 EJP68789.1 - 3.7e-07 30.1 0.0 9.7e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EJP68789.1 - 5.9e-06 25.9 0.0 6.6e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EJP68789.1 - 0.00095 19.8 0.1 0.0013 19.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP68789.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MFS_1 PF07690.16 EJP68790.1 - 9.2e-15 54.4 66.5 1.1e-13 50.8 59.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP68790.1 - 2.5e-07 29.5 13.8 2.5e-07 29.5 13.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_transf_90 PF05686.12 EJP68791.1 - 2.5e-17 62.9 0.0 2.7e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Bd3614_N PF14442.6 EJP68791.1 - 0.052 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal RabGAP-TBC PF00566.18 EJP68792.1 - 3.8e-50 170.5 0.0 5.5e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Tail_spike_N PF18668.1 EJP68792.1 - 0.088 12.7 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain RRM_1 PF00076.22 EJP68793.1 - 7.8e-35 118.5 0.2 5.4e-16 58.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP68793.1 - 5.6e-12 45.6 0.1 7.5e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EJP68793.1 - 0.00011 22.1 0.0 0.36 10.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EJP68793.1 - 0.1 12.6 0.0 12 6.0 0.0 2.7 2 0 0 2 2 2 0 RNA binding motif DUF1365 PF07103.11 EJP68794.1 - 3.2e-58 197.2 0.0 4.7e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MBF1 PF08523.10 EJP68795.1 - 8e-26 90.3 0.8 1.6e-25 89.3 0.8 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EJP68795.1 - 1.7e-09 37.6 0.0 2.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EJP68795.1 - 0.0034 17.7 0.0 0.0074 16.6 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain MRP-L27 PF09809.9 EJP68795.1 - 0.012 15.4 0.2 0.016 15.0 0.2 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L27 Coatomer_E PF04733.14 EJP68797.1 - 4.9e-62 210.0 7.1 5.6e-62 209.8 7.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EJP68797.1 - 5.8e-09 36.3 21.3 0.00021 21.7 1.5 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP68797.1 - 1.9e-08 34.4 0.2 0.13 12.5 0.2 3.3 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EJP68797.1 - 1.6e-05 25.2 2.1 0.032 14.9 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EJP68797.1 - 4.3e-05 22.9 7.6 0.0046 16.2 0.3 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJP68797.1 - 9.2e-05 22.1 1.0 0.072 12.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP68797.1 - 0.0004 20.6 12.4 0.031 14.6 0.4 5.0 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP68797.1 - 0.00098 19.8 20.2 0.0077 17.0 0.4 5.6 5 1 2 7 7 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJP68797.1 - 0.0011 19.0 9.3 0.0048 16.9 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Type_III_YscG PF09477.10 EJP68797.1 - 0.0017 18.4 4.1 0.45 10.6 0.0 3.3 1 1 1 3 3 3 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_16 PF13432.6 EJP68797.1 - 0.0021 18.7 14.2 0.089 13.5 0.5 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJP68797.1 - 0.0041 16.8 1.7 0.062 13.0 0.6 3.5 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 EJP68797.1 - 0.0042 17.2 0.2 1.4 9.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 EJP68797.1 - 0.038 14.1 2.2 0.39 10.8 0.2 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 EJP68797.1 - 0.055 14.1 22.5 0.39 11.5 0.3 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EJP68797.1 - 0.059 13.5 0.8 0.059 13.5 0.8 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 EJP68797.1 - 0.097 11.6 2.4 1.2 7.9 0.2 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Ribosomal_L44 PF00935.19 EJP68798.1 - 3.5e-36 123.5 14.0 5.2e-36 123.0 14.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ureidogly_lyase PF04115.12 EJP68800.1 - 6.4e-53 179.3 0.0 8e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase MFS_1 PF07690.16 EJP68801.1 - 6.3e-10 38.5 7.4 7.4e-10 38.3 6.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68801.1 - 6.6e-06 25.3 0.1 6.6e-06 25.3 0.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter CDH-cyt PF16010.5 EJP68802.1 - 3.9e-20 72.3 0.0 6.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EJP68802.1 - 2.4e-09 37.4 13.5 2.4e-09 37.4 13.5 2.1 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EJP68802.1 - 9.1e-08 31.8 5.2 9.1e-08 31.8 5.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF2157 PF09925.9 EJP68802.1 - 0.013 15.3 17.3 0.044 13.6 4.8 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) XK-related PF09815.9 EJP68802.1 - 0.11 11.6 5.3 0.021 13.9 1.1 1.9 2 0 0 2 2 2 0 XK-related protein TssN PF17555.2 EJP68802.1 - 1.1 8.5 10.3 1.6 8.0 10.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2207 PF09972.9 EJP68802.1 - 2.7 6.7 9.2 3.7 6.2 0.2 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) BaxI_1 PF12811.7 EJP68802.1 - 3.1 7.3 14.8 7 6.1 14.7 1.4 1 1 0 1 1 1 0 Bax inhibitor 1 like DUF4271 PF14093.6 EJP68802.1 - 9.2 6.1 11.3 3.5 7.5 7.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) DUF3275 PF11679.8 EJP68803.1 - 0.84 9.6 5.1 1 9.3 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) HsbA PF12296.8 EJP68804.1 - 1.5e-12 47.9 0.0 2.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FA_hydroxylase PF04116.13 EJP68805.1 - 8.4e-18 65.0 10.2 8.4e-18 65.0 10.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ketoacyl-synt PF00109.26 EJP68806.1 - 3.6e-60 203.7 0.1 6.8e-60 202.8 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EJP68806.1 - 8.4e-59 198.5 0.0 3.8e-58 196.4 0.0 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EJP68806.1 - 4.8e-57 193.9 0.0 7.3e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EJP68806.1 - 3.3e-55 187.4 0.1 1.3e-54 185.4 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EJP68806.1 - 1.8e-31 108.6 0.1 4.2e-31 107.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EJP68806.1 - 7.5e-19 68.2 0.0 7.9e-18 64.9 0.0 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EJP68806.1 - 3e-17 63.2 0.0 1.1e-16 61.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EJP68806.1 - 6.9e-15 55.2 0.3 3.7e-14 52.8 0.1 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EJP68806.1 - 1.4e-13 50.7 0.0 8.5e-12 44.9 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EJP68806.1 - 1.3e-12 48.9 0.0 8.9e-12 46.2 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EJP68806.1 - 2e-09 37.5 0.0 4.8e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP68806.1 - 8.5e-09 36.0 0.0 9.1e-08 32.7 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP68806.1 - 1.2e-08 34.9 0.0 2.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EJP68806.1 - 1.3e-07 31.4 0.0 8.9e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 EJP68806.1 - 6.8e-07 29.9 0.0 2.9e-06 27.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 EJP68806.1 - 1.5e-06 28.5 0.0 4.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 EJP68806.1 - 0.00077 19.3 3.3 0.0027 17.5 0.4 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 EJP68806.1 - 0.0011 18.8 0.2 0.0029 17.5 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EJP68806.1 - 0.0023 17.3 0.2 0.0048 16.3 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 EJP68806.1 - 0.0056 16.4 0.1 0.29 10.8 0.0 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_16 PF10294.9 EJP68806.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase DA1-like PF12315.8 EJP68806.1 - 0.12 11.8 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein DA1 UDPG_MGDP_dh_N PF03721.14 EJP68807.1 - 1.7e-43 148.3 0.3 1.3e-30 106.4 0.0 3.2 1 1 2 3 3 3 3 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EJP68807.1 - 6.9e-33 112.7 0.0 1.1e-31 108.9 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EJP68807.1 - 8.4e-23 80.8 0.0 5.6e-18 65.3 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.23 EJP68807.1 - 0.044 13.8 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_tranf_2_3 PF13641.6 EJP68808.1 - 8.5e-15 55.3 2.1 3.5e-11 43.4 1.4 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 EJP68808.1 - 9.1e-12 44.4 6.6 6.1e-10 38.3 0.0 3.4 3 1 0 3 3 3 2 Chitin synthase Glyco_transf_21 PF13506.6 EJP68808.1 - 5e-11 42.4 0.4 9.6e-11 41.5 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EJP68808.1 - 1.9e-06 27.8 0.1 0.038 13.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EJP68808.1 - 4.9e-06 26.6 27.9 0.00054 19.9 26.0 3.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Pyridoxal_deC PF00282.19 EJP68810.1 - 1.8e-18 66.5 0.0 2.8e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EJP68810.1 - 2.4e-05 23.5 0.0 4.3e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EJP68810.1 - 0.047 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family APH PF01636.23 EJP68811.1 - 9.9e-08 32.2 0.1 8.6e-07 29.1 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP68811.1 - 0.00089 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EJP68811.1 - 0.065 12.6 0.0 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_2 PF02230.16 EJP68813.1 - 3.7e-21 75.9 0.0 2.5e-20 73.2 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EJP68813.1 - 1.6e-05 25.6 1.5 0.018 15.7 0.6 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EJP68813.1 - 1.8e-05 24.3 0.0 0.00053 19.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EJP68813.1 - 0.00037 19.8 0.1 1.3 8.2 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 EJP68813.1 - 0.0067 16.0 0.0 0.032 13.8 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EJP68813.1 - 0.051 13.2 0.0 8.2 6.0 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EJP68813.1 - 0.14 12.0 0.0 7.3 6.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.14 EJP68813.1 - 0.15 11.4 0.0 0.35 10.1 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase NBP1 PF08537.10 EJP68815.1 - 0.00029 20.4 3.8 0.00058 19.4 3.8 1.5 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 HMMR_N PF15905.5 EJP68815.1 - 0.012 15.1 12.9 0.019 14.5 12.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_L PF02601.15 EJP68815.1 - 0.083 12.4 3.3 0.11 12.1 3.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.7 EJP68815.1 - 0.29 11.3 17.6 0.65 10.1 17.6 1.5 1 0 0 1 1 1 0 Tropomyosin like Fzo_mitofusin PF04799.13 EJP68815.1 - 0.53 9.8 3.4 4.8 6.7 3.6 2.2 2 0 0 2 2 2 0 fzo-like conserved region TMPIT PF07851.13 EJP68815.1 - 1.6 7.9 2.9 2.3 7.4 2.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 EJP68815.1 - 2.4 7.2 8.4 4.3 6.3 8.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF745 PF05335.13 EJP68815.1 - 4.4 7.0 14.4 5.2 6.8 11.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) OmpH PF03938.14 EJP68815.1 - 5.7 7.3 11.3 2.8 8.3 8.7 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM76 PF16046.5 EJP68815.1 - 5.9 6.2 7.6 0.3 10.4 1.8 1.7 2 0 0 2 2 2 0 FAM76 protein LPP PF04728.13 EJP68815.1 - 9.9 6.6 7.7 15 6.0 5.9 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper BCDHK_Adom3 PF10436.9 EJP68816.1 - 6.7e-77 256.9 0.0 9.8e-77 256.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EJP68816.1 - 7.4e-13 49.0 0.0 1.7e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EJP68816.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Stc1 PF12898.7 EJP68817.1 - 4.9e-20 71.9 5.1 8.1e-20 71.2 5.1 1.4 1 0 0 1 1 1 1 Stc1 domain GDP_Man_Dehyd PF16363.5 EJP68819.1 - 4.1e-67 226.9 0.0 4.8e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EJP68819.1 - 9.7e-55 185.6 0.1 1.3e-54 185.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EJP68819.1 - 6.2e-24 84.6 0.0 5.9e-23 81.4 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EJP68819.1 - 2.4e-19 69.5 0.1 5.6e-18 65.0 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EJP68819.1 - 3.2e-19 69.0 0.0 4.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EJP68819.1 - 2.7e-18 66.1 0.0 3.9e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EJP68819.1 - 3.8e-06 26.9 0.0 7.2e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Brix PF04427.18 EJP68820.1 - 7.2e-27 94.8 0.1 1.1e-26 94.2 0.1 1.3 1 0 0 1 1 1 1 Brix domain Sporozoite_P67 PF05642.11 EJP68820.1 - 0.23 9.5 2.6 0.32 9.0 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOC3p PF07540.11 EJP68821.1 - 9.1e-32 109.4 1.0 4e-31 107.3 1.0 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 EJP68821.1 - 2.9e-27 95.8 3.4 4.3e-27 95.2 0.0 2.7 2 1 1 3 3 3 1 CBF/Mak21 family BNIP2 PF12496.8 EJP68821.1 - 4.5 7.7 11.9 0.47 10.9 2.1 2.7 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RNase_P_pop3 PF08228.11 EJP68822.1 - 5.7e-10 39.5 0.0 1.1e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 RNase P subunit Pop3 Pkinase PF00069.25 EJP68823.1 - 2.9e-50 171.1 0.0 3.6e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP68823.1 - 1.9e-32 112.6 0.0 2.3e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP68823.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJP68823.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3517 PF12030.8 EJP68825.1 - 5.3e-94 314.9 0.1 1e-93 313.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 EJP68825.1 - 9.2e-40 136.8 0.2 3.4e-39 134.9 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJP68825.1 - 5.5e-24 85.3 0.0 1.1e-23 84.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NOA36 PF06524.12 EJP68826.1 - 2.4 7.4 6.2 4.4 6.5 6.2 1.3 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EJP68826.1 - 5 7.1 5.9 3 7.9 1.2 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal PRCC PF10253.9 EJP68827.1 - 4.1e-28 99.7 18.4 4.1e-28 99.7 18.4 3.2 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Serglycin PF04360.12 EJP68827.1 - 0.0038 17.2 0.1 0.0082 16.1 0.1 1.5 1 0 0 1 1 1 1 Serglycin ApoLp-III PF07464.11 EJP68828.1 - 0.098 12.8 2.3 0.14 12.2 2.3 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) GREB1 PF15782.5 EJP68828.1 - 5.1 4.1 9.0 5.6 3.9 9.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RIFIN PF02009.16 EJP68828.1 - 7.8 6.3 5.0 11 5.8 5.0 1.2 1 0 0 1 1 1 0 Rifin CRIM PF16978.5 EJP68829.1 - 4.6e-43 146.7 0.0 9.1e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EJP68829.1 - 2.2e-31 108.3 0.0 5.2e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EJP68829.1 - 0.00058 20.0 0.0 0.0017 18.5 0.0 1.8 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 EJP68829.1 - 0.0031 17.6 0.0 0.0072 16.4 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain Zip PF02535.22 EJP68831.1 - 7.1e-33 114.2 23.4 7.6e-30 104.3 23.4 3.1 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3742 PF12553.8 EJP68831.1 - 0.22 11.7 4.9 1.7 8.7 0.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) WD40 PF00400.32 EJP68832.1 - 7.5e-37 124.7 22.9 3.3e-07 30.9 0.2 7.2 7 0 0 7 7 6 6 WD domain, G-beta repeat F-box-like PF12937.7 EJP68832.1 - 1.4e-12 47.3 0.6 2.8e-12 46.3 0.6 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EJP68832.1 - 5.3e-09 36.3 0.9 0.34 11.2 0.0 5.8 1 1 6 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP68832.1 - 2.4e-06 26.5 5.9 0.81 8.2 0.1 5.8 1 1 3 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.33 EJP68832.1 - 4.7e-06 26.3 2.1 1e-05 25.2 2.1 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 EJP68832.1 - 0.00028 20.3 0.0 0.059 12.7 0.0 3.0 2 1 1 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 EJP68832.1 - 0.0026 18.2 0.4 6.2 7.4 0.0 4.4 4 0 0 4 4 4 1 PQQ-like domain PALB2_WD40 PF16756.5 EJP68832.1 - 0.014 14.3 2.1 8 5.3 0.0 3.6 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 EJP68832.1 - 0.018 14.6 4.0 0.12 11.9 1.5 3.1 1 1 0 1 1 1 0 PQQ-like domain F-box_5 PF18511.1 EJP68832.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 F-box zf_C2HC_14 PF18574.1 EJP68832.1 - 0.13 12.1 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 C2HC Zing finger domain EH_Signature PF15611.6 EJP68832.1 - 0.13 11.7 0.0 6 6.2 0.0 2.2 2 0 0 2 2 2 0 EH_Signature domain E1_dh PF00676.20 EJP68833.1 - 9.6e-112 372.8 0.3 1.2e-111 372.5 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EJP68833.1 - 0.00078 18.7 0.2 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.21 EJP68834.1 - 4.4e-61 206.1 0.3 1.6e-48 165.1 0.2 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EJP68834.1 - 2.5e-43 148.4 0.0 4.9e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EJP68834.1 - 8.7e-29 100.0 0.0 2.4e-28 98.7 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EJP68834.1 - 5.3e-05 23.6 0.0 8.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Presenilin PF01080.17 EJP68834.1 - 0.32 9.7 1.8 0.52 9.0 1.8 1.3 1 0 0 1 1 1 0 Presenilin Voltage_CLC PF00654.20 EJP68835.1 - 6.5e-89 298.6 27.2 6.5e-89 298.6 27.2 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel LacI PF00356.21 EJP68835.1 - 0.65 9.8 1.9 1.9 8.3 1.9 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Neurochondrin PF05536.11 EJP68836.1 - 1.7e-71 241.4 0.0 2.5e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Neurochondrin RIX1 PF08167.12 EJP68836.1 - 0.0071 16.1 0.0 0.025 14.3 0.0 2.1 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis DUF241 PF03087.14 EJP68837.1 - 0.07 13.0 0.5 0.3 10.9 0.1 1.9 2 0 0 2 2 2 0 Arabidopsis protein of unknown function ATP-synt_D PF01813.17 EJP68837.1 - 0.097 12.5 0.1 0.16 11.8 0.1 1.3 1 1 0 1 1 1 0 ATP synthase subunit D MFS_1 PF07690.16 EJP68838.1 - 2.1e-49 168.4 45.4 2.2e-42 145.2 22.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EJP68838.1 - 4e-10 38.8 20.7 1.4e-07 30.4 7.1 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 EJP68838.1 - 8.2e-09 34.8 6.8 8.2e-09 34.8 6.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EJP68838.1 - 9.8e-07 27.5 17.8 2.7e-05 22.8 8.2 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_4 PF06779.14 EJP68838.1 - 1.3e-05 24.7 17.0 0.00058 19.3 10.0 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EJP68838.1 - 6.9e-05 21.9 14.4 0.00011 21.2 3.3 3.2 3 1 1 4 4 4 2 MFS_1 like family OATP PF03137.20 EJP68838.1 - 0.00049 18.5 0.5 0.00049 18.5 0.5 2.5 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family FAM176 PF14851.6 EJP68838.1 - 0.1 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 FAM176 family CPP1-like PF11833.8 EJP68838.1 - 1 9.0 12.9 0.037 13.7 2.9 2.8 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF1304 PF06993.12 EJP68838.1 - 1.1 9.3 7.9 0.5 10.4 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) Ras PF00071.22 EJP68839.1 - 1.6e-52 177.3 0.0 2e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP68839.1 - 5.5e-19 68.5 0.0 7.5e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP68839.1 - 1.6e-06 27.7 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.21 EJP68840.1 - 4.1e-89 298.8 0.0 5.3e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EJP68840.1 - 0.052 13.8 0.6 0.15 12.3 0.2 1.8 1 1 1 2 2 2 0 UPF0489 domain tRNA-synt_2 PF00152.20 EJP68841.1 - 4e-88 295.5 0.0 5.8e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJP68841.1 - 4.1e-09 36.3 0.0 7.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EJP68841.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Glyco_hydro_31 PF01055.26 EJP68842.1 - 4.9e-150 500.6 0.2 6.1e-150 500.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EJP68842.1 - 1.1e-37 128.7 0.0 2e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EJP68842.1 - 1.1e-15 57.7 2.2 5.9e-15 55.3 0.6 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 EJP68842.1 - 0.17 12.2 0.2 0.39 11.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Glyco_transf_17 PF04724.13 EJP68844.1 - 1.4e-52 178.8 2.1 2.7e-52 177.9 2.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 17 KTI12 PF08433.10 EJP68845.1 - 5.5e-71 239.2 0.0 7.3e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EJP68845.1 - 1.2e-05 25.5 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP68845.1 - 0.0019 18.8 0.0 0.019 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EJP68845.1 - 0.032 14.3 0.0 0.084 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EJP68845.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MIP PF00230.20 EJP68846.1 - 8.1e-45 153.3 15.4 1e-44 152.9 15.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein AAA PF00004.29 EJP68847.1 - 2.3e-98 325.7 0.0 1.1e-47 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP68847.1 - 9.2e-23 79.8 5.2 7.5e-13 48.1 0.3 3.2 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 EJP68847.1 - 2.4e-19 69.3 0.4 9e-19 67.4 0.4 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EJP68847.1 - 1.1e-14 54.4 0.1 6e-06 26.1 0.0 3.8 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EJP68847.1 - 9.5e-14 51.9 0.0 3e-07 30.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EJP68847.1 - 2.3e-13 50.9 0.0 0.00021 21.7 0.0 4.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 EJP68847.1 - 3.8e-12 46.6 0.0 3.6e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EJP68847.1 - 4e-12 46.3 0.3 3.5e-06 27.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EJP68847.1 - 2.3e-09 37.7 0.4 0.029 14.7 0.1 4.0 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 EJP68847.1 - 2.7e-09 36.7 0.1 0.0014 17.9 0.0 2.9 2 1 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EJP68847.1 - 1.8e-07 30.9 0.0 4.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 EJP68847.1 - 1.9e-07 31.7 0.0 0.027 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EJP68847.1 - 2.1e-07 30.6 0.2 0.0069 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EJP68847.1 - 2.5e-07 30.8 0.0 0.0076 16.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EJP68847.1 - 3e-07 30.3 0.0 0.019 14.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EJP68847.1 - 6.6e-07 29.7 0.0 0.036 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ATPase PF06745.13 EJP68847.1 - 1.1e-06 28.1 0.3 0.25 10.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 EJP68847.1 - 2.1e-06 27.4 0.1 0.032 13.7 0.0 2.9 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EJP68847.1 - 2.9e-06 27.0 3.7 0.17 11.4 0.0 4.2 3 2 2 5 5 4 2 AAA domain AAA_24 PF13479.6 EJP68847.1 - 4.2e-06 26.6 0.0 0.082 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 EJP68847.1 - 6.5e-06 25.5 0.0 0.016 14.4 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 EJP68847.1 - 8.1e-06 25.1 0.1 0.052 12.6 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Vps4_C PF09336.10 EJP68847.1 - 1.3e-05 25.1 1.1 9.6e-05 22.3 0.1 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 EJP68847.1 - 1.6e-05 25.2 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EJP68847.1 - 2.3e-05 24.2 0.0 0.25 11.0 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EJP68847.1 - 3.2e-05 24.5 0.0 0.28 11.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.18 EJP68847.1 - 5.2e-05 23.2 0.0 0.18 11.6 0.0 2.8 3 0 0 3 3 2 2 Bacterial dnaA protein TsaE PF02367.17 EJP68847.1 - 6.5e-05 22.9 0.0 0.41 10.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EJP68847.1 - 0.00013 21.9 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 EJP68847.1 - 0.00015 21.8 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EJP68847.1 - 0.00017 21.4 0.0 0.7 9.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EJP68847.1 - 0.00017 22.0 0.1 0.59 10.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain PhoH PF02562.16 EJP68847.1 - 0.00022 20.7 0.3 0.67 9.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 EJP68847.1 - 0.00036 20.4 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EJP68847.1 - 0.00046 19.9 0.3 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EJP68847.1 - 0.00052 20.0 0.0 3.6 7.4 0.0 3.6 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EJP68847.1 - 0.001 19.4 0.3 5.5 7.3 0.0 3.6 3 1 1 4 4 3 0 AAA domain DUF2075 PF09848.9 EJP68847.1 - 0.002 17.4 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 EJP68847.1 - 0.0036 17.4 0.0 0.55 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 EJP68847.1 - 0.0044 16.2 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 EJP68847.1 - 0.0048 16.8 0.5 2.5 8.0 0.0 4.0 4 0 0 4 4 3 1 NTPase Viral_helicase1 PF01443.18 EJP68847.1 - 0.007 16.1 0.0 0.33 10.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.16 EJP68847.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 EJP68847.1 - 0.013 14.9 0.0 0.1 12.0 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Zeta_toxin PF06414.12 EJP68847.1 - 0.028 13.7 1.0 7.9 5.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin KAP_NTPase PF07693.14 EJP68847.1 - 0.031 13.5 0.5 1.1 8.4 0.0 3.1 2 2 1 4 4 4 0 KAP family P-loop domain AAA_6 PF12774.7 EJP68847.1 - 0.049 12.6 0.1 7.6 5.4 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 EJP68847.1 - 0.057 13.2 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 EJP68847.1 - 0.057 13.1 0.0 3 7.5 0.0 3.1 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) Cytidylate_kin2 PF13189.6 EJP68847.1 - 0.063 13.4 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family AFG1_ATPase PF03969.16 EJP68847.1 - 0.085 11.7 0.0 9.6 5.0 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase EnY2 PF10163.9 EJP68848.1 - 0.05 14.0 0.1 0.1 13.0 0.0 1.5 2 0 0 2 2 2 0 Transcription factor e(y)2 FpoO PF10621.9 EJP68848.1 - 0.084 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO ABC_tran PF00005.27 EJP68849.1 - 3e-33 115.2 0.0 8.1e-33 113.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EJP68849.1 - 3.1e-27 95.9 4.7 3.1e-27 95.9 4.7 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EJP68849.1 - 3e-05 23.6 0.0 9.4e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EJP68849.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 EJP68849.1 - 0.036 14.3 0.2 0.77 10.0 0.2 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EJP68849.1 - 0.06 13.1 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EJP68849.1 - 0.069 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GARS_C PF02843.16 EJP68849.1 - 0.19 12.1 0.5 0.69 10.2 0.2 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain TRAM_LAG1_CLN8 PF03798.16 EJP68850.1 - 1.3e-34 119.7 21.1 1.3e-34 119.7 21.1 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EJP68850.1 - 4.9e-26 90.2 0.0 4.9e-26 90.2 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein PalH PF08733.10 EJP68851.1 - 5.2e-102 341.2 0.6 6.9e-102 340.8 0.6 1.1 1 0 0 1 1 1 1 PalH/RIM21 YjeF_N PF03853.15 EJP68852.1 - 6e-38 130.4 0.0 1.2e-37 129.4 0.0 1.5 1 1 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EJP68852.1 - 2.1e-09 38.2 1.8 2.1e-09 38.2 1.8 2.1 2 0 0 2 2 2 1 FDF domain PDE6_gamma PF04868.12 EJP68852.1 - 0.14 12.5 0.5 0.39 11.0 0.5 1.8 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit PIF1 PF05970.14 EJP68853.1 - 1.9e-62 211.6 0.1 9.6e-50 169.8 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EJP68853.1 - 2e-22 79.8 0.0 3.8e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP68853.1 - 6.1e-10 39.6 0.0 1.2e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJP68853.1 - 1.6e-07 31.7 0.0 4.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EJP68853.1 - 5.4e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EJP68853.1 - 1.9e-05 25.1 0.1 4.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 EJP68853.1 - 0.00021 21.1 0.0 0.00062 19.5 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EJP68853.1 - 0.00026 19.1 0.1 0.001 17.1 0.0 1.9 2 0 0 2 2 2 1 Helicase ABC_tran PF00005.27 EJP68853.1 - 0.00033 21.2 0.3 0.0018 18.8 0.1 2.6 2 1 0 2 2 1 1 ABC transporter AAA_16 PF13191.6 EJP68853.1 - 0.00049 20.5 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 EJP68853.1 - 0.0016 18.2 0.1 0.2 11.4 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 EJP68853.1 - 0.002 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.6 EJP68853.1 - 0.0028 17.5 0.0 0.0028 17.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EJP68853.1 - 0.0049 16.9 0.1 0.016 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 EJP68853.1 - 0.0058 16.1 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 EJP68853.1 - 0.0081 15.4 0.0 0.02 14.1 0.0 1.7 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EJP68853.1 - 0.0084 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 EJP68853.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 EJP68853.1 - 0.013 15.2 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EJP68853.1 - 0.015 14.7 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EJP68853.1 - 0.026 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 EJP68853.1 - 0.033 14.2 0.0 0.15 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EJP68853.1 - 0.034 13.9 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 EJP68853.1 - 0.035 14.0 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EJP68853.1 - 0.036 13.2 0.0 0.47 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EJP68853.1 - 0.038 13.2 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 EJP68853.1 - 0.082 12.8 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 EJP68853.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSM PF04612.12 EJP68853.1 - 0.092 12.8 4.9 0.037 14.1 2.2 1.7 2 0 0 2 2 1 0 Type II secretion system (T2SS), protein M Sigma54_activat PF00158.26 EJP68853.1 - 0.099 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 EJP68853.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 EJP68853.1 - 0.13 12.4 0.0 0.55 10.3 0.1 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 EJP68853.1 - 0.63 10.1 3.3 5.5 7.0 0.1 2.6 1 1 1 2 2 2 0 Helicase HerA, central domain SieB PF14163.6 EJP68854.1 - 0.65 9.5 3.0 3.1 7.3 1.7 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF1771 PF08590.10 EJP68855.1 - 6.4e-24 84.1 7.9 1.5e-23 82.9 7.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EJP68855.1 - 6.7e-09 36.0 0.3 6.7e-09 36.0 0.3 2.3 2 1 1 3 3 3 1 Smr domain DUF4407 PF14362.6 EJP68855.1 - 0.027 13.8 1.9 0.046 13.1 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM53 PF15242.6 EJP68856.1 - 0.00049 20.0 3.9 0.00067 19.6 3.9 1.2 1 0 0 1 1 1 1 Family of FAM53 Dicty_REP PF05086.12 EJP68856.1 - 0.21 9.5 2.2 0.25 9.3 2.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PBP1_TM PF14812.6 EJP68856.1 - 3.4 8.1 11.1 0.13 12.6 2.9 2.2 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal G-alpha PF00503.20 EJP68857.1 - 7.1e-125 416.8 1.5 8.2e-125 416.6 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EJP68857.1 - 1.2e-15 57.4 1.2 1.1e-10 41.3 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EJP68857.1 - 6.7e-05 22.6 0.0 0.00028 20.6 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EJP68857.1 - 0.001 18.5 2.6 0.07 12.5 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EJP68857.1 - 0.015 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EJP68857.1 - 0.017 15.3 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EJP68857.1 - 0.099 12.7 0.1 6.2 6.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJP68857.1 - 0.1 12.1 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 EJP68857.1 - 0.11 11.6 0.1 0.21 10.7 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain DUF3716 PF12511.8 EJP68858.1 - 3.4e-16 59.0 9.9 5.1e-16 58.4 9.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) D123 PF07065.14 EJP68859.1 - 3.2e-114 381.2 0.0 3.7e-114 381.0 0.0 1.0 1 0 0 1 1 1 1 D123 DUF3470 PF11953.8 EJP68859.1 - 0.13 12.2 1.1 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3470) cwf21 PF08312.12 EJP68860.1 - 1.5e-17 63.4 13.8 3.4e-17 62.3 13.8 1.6 1 0 0 1 1 1 1 cwf21 domain GvpG PF05120.12 EJP68860.1 - 0.22 11.5 5.9 0.95 9.5 2.2 2.2 2 0 0 2 2 2 0 Gas vesicle protein G Trans_reg_C PF00486.28 EJP68860.1 - 0.32 11.1 0.1 0.32 11.1 0.1 2.1 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal Use1 PF09753.9 EJP68861.1 - 2.1e-08 34.2 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 CDC27 PF09507.10 EJP68861.1 - 0.93 8.8 11.0 1.3 8.3 11.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nucleo_P87 PF07267.11 EJP68861.1 - 2.3 6.9 5.6 3.4 6.4 5.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CD52 PF15116.6 EJP68861.1 - 5 7.2 5.5 4.7 7.3 3.4 2.1 1 1 1 2 2 2 0 CAMPATH-1 antigen Hamartin PF04388.12 EJP68861.1 - 8.9 4.8 12.8 11 4.6 12.8 1.0 1 0 0 1 1 1 0 Hamartin protein IGPS PF00218.21 EJP68863.1 - 6.9e-94 313.8 0.0 1.2e-93 313.0 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EJP68863.1 - 1e-47 162.5 0.1 2.1e-42 145.1 0.0 2.4 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EJP68863.1 - 4e-46 157.2 0.0 9.5e-46 156.0 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EJP68863.1 - 2.3e-05 24.2 0.5 0.00013 21.8 0.1 2.3 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.19 EJP68863.1 - 0.0041 16.9 1.3 0.19 11.5 0.3 2.6 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Nup188_C PF18378.1 EJP68864.1 - 2.4e-147 490.6 0.0 4.3e-147 489.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EJP68864.1 - 7.3e-50 169.8 6.8 4.7e-35 120.8 1.8 2.3 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 zf-Tim10_DDP PF02953.15 EJP68865.1 - 2.2e-19 68.9 1.9 3.2e-19 68.3 1.9 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Hormone_recep PF00104.30 EJP68865.1 - 0.014 14.9 0.9 0.015 14.9 0.9 1.0 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor AP3D1 PF06375.11 EJP68866.1 - 0.0035 17.6 7.8 0.0046 17.2 7.8 1.2 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 SR-25 PF10500.9 EJP68866.1 - 0.072 12.7 12.9 0.097 12.3 12.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4710 PF15828.5 EJP68866.1 - 0.12 12.5 12.6 0.23 11.6 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) OAD_gamma PF04277.13 EJP68866.1 - 0.37 11.4 4.4 0.55 10.8 4.4 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.10 EJP68866.1 - 0.41 10.7 7.0 0.55 10.3 7.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Eapp_C PF10238.9 EJP68866.1 - 0.9 9.6 9.5 1.9 8.6 9.5 1.5 1 1 0 1 1 1 0 E2F-associated phosphoprotein VIGSSK PF14773.6 EJP68866.1 - 3.5 7.8 5.7 6.2 7.0 5.7 1.4 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal Rtf2 PF04641.12 EJP68866.1 - 7.6 5.8 16.5 9.5 5.5 16.5 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger DUF1640 PF07798.11 EJP68867.1 - 6.9e-55 185.8 7.7 9.8e-55 185.3 7.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) 2-Hacid_dh_C PF02826.19 EJP68867.1 - 4e-51 172.9 0.0 6.5e-51 172.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJP68867.1 - 2.3e-19 69.4 0.0 8.2e-19 67.6 0.0 1.9 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EJP68867.1 - 0.037 14.2 2.4 0.072 13.3 0.2 2.4 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase GNAT_acetyltr_2 PF13718.6 EJP68867.1 - 0.1 12.0 0.1 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 GNAT acetyltransferase 2 cwf21 PF08312.12 EJP68867.1 - 0.23 11.7 2.7 0.33 11.2 1.0 2.1 2 0 0 2 2 2 0 cwf21 domain AdoHcyase PF05221.17 EJP68868.1 - 1e-129 432.0 0.0 3.8e-74 249.5 0.3 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EJP68868.1 - 5.2e-83 277.0 2.4 8.1e-83 276.3 2.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EJP68868.1 - 9.5e-06 25.1 0.2 2e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EJP68868.1 - 0.013 15.1 0.4 0.027 14.1 0.4 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 EJP68868.1 - 0.064 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 EJP68868.1 - 0.065 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EJP68868.1 - 0.13 12.1 0.4 0.22 11.4 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain JAB PF01398.21 EJP68869.1 - 2.1e-06 27.7 0.1 6.2e-05 23.0 0.1 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mito_carr PF00153.27 EJP68871.1 - 2.4e-18 65.8 1.6 6.5e-10 38.8 0.2 2.9 2 1 0 2 2 2 2 Mitochondrial carrier protein SpoIIE PF07228.12 EJP68872.1 - 1.8e-11 44.3 0.2 9.2e-11 42.0 0.1 1.9 1 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EJP68872.1 - 4.2e-07 29.8 2.6 4.2e-07 29.8 2.6 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 EJP68872.1 - 5e-05 23.0 0.1 0.09 12.4 0.1 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C Flu_B_M2 PF04772.12 EJP68872.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Toxin_30 PF08117.11 EJP68873.1 - 0.00013 22.1 8.6 0.48 10.7 0.4 4.0 3 0 0 3 3 3 3 Ptu family BRO1 PF03097.18 EJP68874.1 - 6.8e-05 21.8 0.0 8.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain DUF5641 PF18701.1 EJP68874.1 - 0.2 11.8 0.0 0.41 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5641) Caskin-Pro-rich PF16907.5 EJP68874.1 - 0.25 11.9 1.4 13 6.3 1.0 2.5 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Cnd2 PF05786.14 EJP68875.1 - 0.054 12.2 1.7 0.068 11.8 1.7 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 PCSK9_C1 PF18459.1 EJP68875.1 - 1.8 8.7 4.7 4.3 7.5 0.1 2.6 2 1 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Endonuclease_NS PF01223.23 EJP68876.1 - 6.7e-69 232.2 0.0 8.1e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Mito_carr PF00153.27 EJP68877.1 - 2e-15 56.5 0.2 1.3e-09 37.9 0.0 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF5437 PF17505.2 EJP68877.1 - 7.9 6.6 6.5 0.66 10.1 0.3 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5437) MBOAT PF03062.19 EJP68879.1 - 1.2e-19 70.9 18.8 1.2e-19 70.9 18.8 1.7 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EJP68879.1 - 0.00051 20.3 3.4 0.0017 18.6 3.4 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF1201 PF06716.11 EJP68879.1 - 7.2 6.7 9.8 0.57 10.2 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1201) ICMT PF04140.14 EJP68880.1 - 1.6e-27 95.7 0.2 3.7e-27 94.6 0.2 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EJP68880.1 - 1.6e-12 47.8 0.7 1.6e-12 47.8 0.7 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EJP68880.1 - 0.00061 19.4 0.2 0.00092 18.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Tmemb_170 PF10190.9 EJP68881.1 - 6.1e-33 113.4 12.0 7e-33 113.2 12.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF1275 PF06912.11 EJP68881.1 - 0.095 12.6 6.5 0.29 11.0 6.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) DAG1 PF05454.11 EJP68881.1 - 0.37 10.1 0.4 0.72 9.2 0.1 1.6 2 1 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Peptidase_U4 PF03419.13 EJP68881.1 - 4.4 6.5 8.3 5.6 6.2 8.3 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA PI-PLC-X PF00388.19 EJP68884.1 - 1.3e-62 209.6 0.0 2e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EJP68884.1 - 2.2e-42 144.0 0.0 4.4e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain ArAE_2_N PF10337.9 EJP68885.1 - 4.8e-97 325.9 0.2 5.8e-95 319.1 0.1 2.4 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EJP68885.1 - 5.4e-39 134.4 0.3 1.1e-38 133.4 0.1 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EJP68885.1 - 3.3e-09 36.9 16.5 3.3e-09 36.9 16.5 4.2 3 1 1 4 4 4 1 Fusaric acid resistance protein-like ALMT PF11744.8 EJP68885.1 - 0.0005 19.0 10.9 0.0005 19.0 10.9 2.0 2 0 0 2 2 2 1 Aluminium activated malate transporter MFS_1 PF07690.16 EJP68886.1 - 3.7e-22 78.8 36.4 1.3e-12 47.3 8.6 3.5 3 1 1 4 4 4 4 Major Facilitator Superfamily ATG22 PF11700.8 EJP68886.1 - 6.4e-06 25.1 4.9 1.4e-05 23.9 0.0 3.0 4 1 1 5 5 5 1 Vacuole effluxer Atg22 like LacY_symp PF01306.19 EJP68886.1 - 0.93 8.2 9.8 0.096 11.4 1.6 2.7 3 0 0 3 3 3 0 LacY proton/sugar symporter Actin PF00022.19 EJP68887.1 - 2.4e-28 98.9 0.0 3.9e-19 68.5 0.0 2.9 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 EJP68887.1 - 0.0016 17.7 3.6 0.22 10.7 0.1 2.9 3 0 0 3 3 3 2 Putative actin-like family FtsA PF14450.6 EJP68887.1 - 0.0026 18.2 0.0 0.019 15.4 0.0 2.4 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 EJP68887.1 - 0.022 13.6 0.0 0.39 9.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein DUF2236 PF09995.9 EJP68888.1 - 7.4e-07 29.6 0.8 1.3e-06 28.8 0.8 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2561 PF10812.8 EJP68888.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) SOG2 PF10428.9 EJP68889.1 - 0.17 11.1 9.5 0.17 11.1 9.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4451 PF14616.6 EJP68890.1 - 4.6e-24 85.0 0.1 1e-23 83.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF463 PF04317.12 EJP68890.1 - 0.35 9.7 1.9 0.65 8.9 0.0 2.0 2 0 0 2 2 2 0 YcjX-like family, DUF463 Iso_dh PF00180.20 EJP68892.1 - 1.3e-94 317.2 0.0 1.6e-94 316.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AA_permease PF00324.21 EJP68893.1 - 1.2e-60 205.5 36.8 1.6e-59 201.7 36.8 2.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP68893.1 - 6.8e-26 91.1 32.3 9.1e-26 90.6 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease OPT PF03169.15 EJP68895.1 - 9.4e-143 477.1 46.9 1.1e-142 476.9 46.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SLATT_1 PF18181.1 EJP68895.1 - 0.88 9.5 0.0 0.88 9.5 0.0 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 HMGL-like PF00682.19 EJP68896.1 - 2.6e-72 243.5 0.0 4.3e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 HMGL-like COesterase PF00135.28 EJP68897.1 - 1.5e-62 212.1 0.0 4.3e-61 207.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EJP68897.1 - 7.2e-08 32.5 2.6 3.3e-07 30.4 2.6 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EJP68898.1 - 2.2e-22 80.0 0.0 2e-10 40.9 0.0 3.0 2 1 0 3 3 3 3 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EJP68898.1 - 5.5e-07 29.3 0.0 9.9e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EJP68898.1 - 0.00028 20.2 0.3 0.87 8.8 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 LIP PF03583.14 EJP68898.1 - 0.00074 18.9 0.0 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Secretory lipase DLH PF01738.18 EJP68898.1 - 0.069 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 EJP68898.1 - 0.092 12.7 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal NAD_kinase PF01513.21 EJP68899.1 - 5.1e-45 153.9 0.0 8.1e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EJP68899.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Cu-oxidase_3 PF07732.15 EJP68900.1 - 3.5e-39 133.5 1.1 1.9e-38 131.1 0.2 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP68900.1 - 3.9e-32 110.8 9.7 3e-25 88.5 0.3 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 EJP68900.1 - 8.3e-19 68.3 0.0 7.7e-14 52.1 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase EF-1_beta_acid PF10587.9 EJP68901.1 - 0.24 11.9 2.2 0.55 10.7 2.2 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region UQ_con PF00179.26 EJP68902.1 - 5e-41 139.6 0.0 2.1e-29 102.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.13 EJP68902.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.11 EJP68902.1 - 0.053 13.2 0.0 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 EJP68902.1 - 0.12 12.7 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 RWD domain DUF3293 PF11697.8 EJP68902.1 - 0.15 12.6 0.0 0.43 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) Rep_fac_C PF08542.11 EJP68903.1 - 1.1e-22 80.2 0.0 2.4e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EJP68903.1 - 1.3e-15 58.0 0.0 4.4e-15 56.3 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EJP68903.1 - 2.1e-12 47.1 0.0 7.7e-11 42.0 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EJP68903.1 - 1.8e-09 37.8 0.0 4.3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EJP68903.1 - 5.7e-06 26.6 0.0 0.00021 21.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EJP68903.1 - 1.2e-05 25.1 0.1 2.6e-05 24.0 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EJP68903.1 - 2.3e-05 24.4 0.1 5.5e-05 23.1 0.0 1.6 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EJP68903.1 - 6e-05 22.5 0.0 0.0017 17.8 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EJP68903.1 - 7.7e-05 23.1 0.0 0.0015 18.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_assoc_2 PF16193.5 EJP68903.1 - 0.00054 20.2 0.1 0.0016 18.8 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 EJP68903.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP68903.1 - 0.0025 18.2 0.0 0.012 15.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EJP68903.1 - 0.0034 17.1 0.0 0.0092 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EJP68903.1 - 0.004 16.7 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 EJP68903.1 - 0.0061 15.7 0.0 0.0093 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EJP68903.1 - 0.014 15.4 0.1 0.092 12.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EJP68903.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EJP68903.1 - 0.016 15.3 0.0 0.089 12.8 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EJP68903.1 - 0.024 14.3 0.0 0.095 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EJP68903.1 - 0.041 13.1 0.0 0.096 11.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta PF06144.13 EJP68903.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_3 PF07726.11 EJP68903.1 - 0.066 13.1 0.0 0.34 10.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EJP68903.1 - 0.088 13.4 0.0 0.24 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EJP68903.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 EJP68903.1 - 0.16 11.7 0.3 1.9 8.2 0.0 2.4 2 1 1 3 3 2 0 DEAD/DEAH box helicase DUF2802 PF10975.8 EJP68904.1 - 0.097 12.8 2.8 0.11 12.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Exonuc_VII_S PF02609.16 EJP68904.1 - 0.52 10.4 3.2 3.2 7.9 0.1 2.6 2 0 0 2 2 2 0 Exonuclease VII small subunit Sec63 PF02889.16 EJP68906.1 - 5.7e-164 543.5 0.0 2e-91 305.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EJP68906.1 - 1.4e-50 171.5 0.0 7.3e-29 100.8 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EJP68906.1 - 1.2e-33 115.6 0.3 3.3e-33 114.2 0.3 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EJP68906.1 - 1.2e-23 83.9 0.0 2.8e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EJP68906.1 - 1.4e-10 41.5 0.0 4.2e-07 30.3 0.0 3.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EJP68906.1 - 6.7e-07 29.6 0.1 0.015 15.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 EJP68906.1 - 0.0015 17.6 0.0 0.98 8.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 EJP68906.1 - 0.0087 15.5 0.0 0.33 10.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein TFIIE_alpha PF02002.17 EJP68906.1 - 0.044 13.6 0.2 3.3 7.6 0.0 3.1 2 0 0 2 2 2 0 TFIIE alpha subunit AAA_7 PF12775.7 EJP68906.1 - 0.085 12.4 0.1 3.9 6.9 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region Dala_Dala_lig_N PF01820.21 EJP68906.1 - 0.15 12.5 0.1 0.6 10.6 0.1 2.0 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus PWWP PF00855.17 EJP68907.1 - 6.5e-13 48.9 0.0 6.5e-13 48.9 0.0 3.2 3 1 0 3 3 3 1 PWWP domain Med26 PF08711.11 EJP68907.1 - 0.00025 21.0 0.2 0.00065 19.7 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DFF-C PF09033.10 EJP68907.1 - 1.5 8.7 10.6 0.96 9.3 6.4 2.5 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain ORC3_N PF07034.11 EJP68908.1 - 2e-43 148.8 0.6 1.1e-41 143.1 0.6 2.5 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EJP68908.1 - 5.6e-31 107.5 0.1 2.1e-30 105.6 0.0 2.0 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal AP4E_app_platf PF14807.6 EJP68908.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform CENP-B_dimeris PF09026.10 EJP68908.1 - 0.25 11.7 3.9 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EJP68908.1 - 1.6 9.0 5.7 15 5.9 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Macoilin PF09726.9 EJP68909.1 - 0.0082 14.8 0.6 0.0089 14.6 0.6 1.1 1 0 0 1 1 1 1 Macoilin family SPX PF03105.19 EJP68909.1 - 0.0098 15.9 2.4 0.014 15.4 2.4 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 EJP68909.1 - 0.21 10.4 2.7 0.21 10.4 2.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAM-associated PF14303.6 EJP68909.1 - 2.3 8.9 6.6 4.1 8.1 6.6 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain NICE-1 PF15845.5 EJP68909.1 - 2.4 9.0 20.2 0.29 11.9 15.8 1.7 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family Med3 PF11593.8 EJP68909.1 - 7.1 5.7 8.7 9.4 5.3 8.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sec66 PF09802.9 EJP68910.1 - 9.1e-78 260.0 0.1 1e-77 259.8 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 EJP68910.1 - 0.0036 17.3 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3848) Mst1_SARAH PF11629.8 EJP68910.1 - 0.15 12.2 0.7 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 NPL4 PF05021.15 EJP68911.1 - 2.7e-139 463.8 0.0 3.5e-139 463.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EJP68911.1 - 1.8e-66 222.7 0.0 3.1e-66 222.0 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EJP68911.1 - 0.02 15.4 0.0 0.22 12.0 0.0 2.2 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 CPSase_L_D2 PF02786.17 EJP68912.1 - 2.2e-111 370.4 0.0 2.5e-84 282.0 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EJP68912.1 - 1.3e-40 138.5 0.1 3.7e-40 137.1 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EJP68912.1 - 1.9e-22 79.6 0.1 3.5e-11 43.0 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EJP68912.1 - 1.6e-19 70.3 0.4 2.1e-09 37.2 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EJP68912.1 - 1e-11 44.7 0.0 7e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 EJP68912.1 - 1.7e-05 24.7 0.2 0.11 12.3 0.1 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 EJP68912.1 - 2.8e-05 24.2 0.1 0.26 11.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 EJP68912.1 - 5.9e-05 22.6 0.1 0.12 11.8 0.1 3.0 2 1 1 3 3 3 2 ATP-grasp domain RimK PF08443.11 EJP68912.1 - 7.8e-05 22.4 0.1 0.053 13.1 0.1 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 EJP68912.1 - 0.00079 19.0 0.0 0.011 15.4 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.22 EJP68912.1 - 0.05 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 MGS-like domain MARVEL PF01284.23 EJP68914.1 - 3e-06 27.3 7.0 4.7e-06 26.7 7.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF836 PF05768.14 EJP68915.1 - 5.9e-12 45.8 0.0 7.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EJP68915.1 - 0.0019 18.4 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin HpcH_HpaI PF03328.14 EJP68916.1 - 1.7e-34 118.9 0.1 2.1e-34 118.6 0.1 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 EJP68916.1 - 0.009 15.5 0.9 2.1 7.7 0.1 2.9 2 1 1 3 3 3 2 Phosphoenolpyruvate phosphomutase SHS2_Rpb7-N PF03876.17 EJP68917.1 - 1.1e-14 54.5 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EJP68917.1 - 6e-12 45.7 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 EJP68918.1 - 2.9e-25 88.2 2.4 7.4e-25 86.9 2.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Peptidase_U4 PF03419.13 EJP68918.1 - 0.28 10.4 3.7 0.31 10.3 3.7 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA ABC2_membrane_2 PF12679.7 EJP68918.1 - 0.89 8.8 5.9 1.5 8.0 5.8 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein MARVEL PF01284.23 EJP68918.1 - 1.1 9.3 8.6 0.4 10.7 4.7 2.0 1 1 1 2 2 2 0 Membrane-associating domain TctB PF07331.11 EJP68918.1 - 1.1 9.5 9.8 2.3 8.5 9.8 1.6 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Isochorismatase PF00857.20 EJP68920.1 - 1.3e-18 67.7 0.0 1.6e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PAXX PF15384.6 EJP68920.1 - 0.042 13.5 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Glyco_hydro_15 PF00723.21 EJP68921.1 - 2.3e-52 178.3 0.0 2.9e-49 168.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 MFS_1 PF07690.16 EJP68922.1 - 2.5e-37 128.6 29.1 1.3e-36 126.3 30.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP68922.1 - 2.2e-11 43.3 18.0 3.9e-11 42.5 18.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TPT PF03151.16 EJP68923.1 - 1.4e-21 77.1 11.3 2e-21 76.6 11.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EJP68923.1 - 3.4e-06 27.3 32.6 0.0084 16.3 8.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EJP68923.1 - 0.00014 21.3 14.0 0.00021 20.7 13.5 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 EJP68923.1 - 0.15 11.2 15.4 0.29 10.3 15.4 1.3 1 0 0 1 1 1 0 UAA transporter family Pneumo_att_G PF05539.11 EJP68923.1 - 4.4 6.8 8.4 7.6 6.0 8.4 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SLATT_1 PF18181.1 EJP68923.1 - 5.3 7.0 4.9 5.4 7.0 0.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 RRM_1 PF00076.22 EJP68924.1 - 1.2e-18 66.7 0.1 2.2e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 EJP68924.1 - 0.04 14.3 0.0 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 Cytotoxic OB_RNB PF08206.11 EJP68924.1 - 0.15 11.8 0.2 0.31 10.8 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain RecU PF03838.14 EJP68924.1 - 0.21 11.6 0.4 0.36 10.8 0.4 1.3 1 0 0 1 1 1 0 Recombination protein U SWI-SNF_Ssr4 PF08549.10 EJP68925.1 - 1e-262 874.1 9.0 1.9e-262 873.1 9.0 1.4 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) GPI-anchored PF10342.9 EJP68926.1 - 0.002 18.8 0.1 0.0055 17.4 0.1 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Zip PF02535.22 EJP68926.1 - 0.16 11.1 0.9 0.22 10.7 0.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 EJP68926.1 - 0.7 8.6 8.7 1.1 8.0 8.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MMU163 PF17119.5 EJP68926.1 - 2.3 7.3 9.5 4.4 6.4 9.5 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF3357 PF11837.8 EJP68927.1 - 0.0045 17.4 1.4 0.059 13.8 0.7 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3357) Asp PF00026.23 EJP68928.1 - 3.1e-56 191.1 0.1 8.5e-56 189.7 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP68928.1 - 1.3e-07 32.0 0.1 7.7e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EJP68928.1 - 0.01 15.6 0.0 0.29 10.9 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EJP68928.1 - 0.11 13.2 0.2 8.4 7.1 0.0 3.4 4 0 0 4 4 4 0 Aspartyl protease Ferric_reduct PF01794.19 EJP68929.1 - 4.1e-22 78.6 15.6 4.1e-22 78.6 15.6 3.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EJP68929.1 - 7.2e-10 39.2 0.0 1.7e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EJP68929.1 - 3.1e-08 33.7 0.0 6.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 EJP68929.1 - 0.0014 19.1 14.6 0.053 14.1 1.2 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) NAD_binding_1 PF00175.21 EJP68929.1 - 0.046 14.4 0.0 0.8 10.4 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF5090 PF17009.5 EJP68929.1 - 6.5 6.7 9.1 12 5.9 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) MOSC PF03473.17 EJP68930.1 - 1.4e-38 131.8 0.0 2.8e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 EJP68930.1 - 1.5e-22 80.1 0.0 1.9e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 EJP68930.1 - 2.6e-21 75.7 0.0 4.4e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Cytochrom_C1 PF02167.15 EJP68932.1 - 1.5e-91 306.0 0.0 1.9e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EJP68932.1 - 0.0043 17.3 0.0 0.0088 16.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EJP68932.1 - 0.052 14.7 0.0 0.24 12.6 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c LRR_4 PF12799.7 EJP68933.1 - 2.1e-07 31.1 7.4 0.61 10.6 0.0 5.5 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EJP68933.1 - 6.3e-07 29.0 5.7 0.12 12.5 0.0 6.6 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 EJP68933.1 - 0.00012 22.1 0.4 11 7.0 0.1 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 EJP68933.1 - 0.0065 16.2 8.9 2.8 7.8 0.1 4.9 4 1 0 4 4 4 2 Leucine rich repeat YueH PF14166.6 EJP68934.1 - 0.063 13.2 0.6 0.16 11.8 0.6 1.7 1 0 0 1 1 1 0 YueH-like protein Epimerase PF01370.21 EJP68935.1 - 2.8e-24 85.9 0.0 4e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP68935.1 - 1.3e-22 80.7 0.1 6.3e-16 58.7 0.0 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EJP68935.1 - 1.9e-11 43.7 0.5 2.1e-07 30.4 0.0 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EJP68935.1 - 7.2e-11 41.7 0.0 1.7e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EJP68935.1 - 1.6e-08 34.1 0.4 1.6e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EJP68935.1 - 2e-05 23.8 0.0 0.00012 21.2 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_transf_25 PF01755.17 EJP68936.1 - 2.1e-11 44.1 0.0 3.7e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Proteasome PF00227.26 EJP68937.1 - 6.5e-43 146.4 0.2 7.1e-29 100.7 0.0 2.3 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EJP68937.1 - 6e-11 41.8 0.2 1.4e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DNA_pol_phi PF04931.13 EJP68938.1 - 1.8e-191 638.1 38.7 3.7e-191 637.1 38.7 1.5 1 1 0 1 1 1 1 DNA polymerase phi HEAT_2 PF13646.6 EJP68938.1 - 0.0042 17.5 7.6 1 9.8 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 EJP68938.1 - 0.0063 16.7 1.4 0.058 13.6 0.1 3.2 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 KIAA1430 PF13879.6 EJP68938.1 - 0.0076 17.0 0.4 0.043 14.6 0.4 2.3 1 0 0 1 1 1 1 KIAA1430 homologue DUF29 PF01724.16 EJP68938.1 - 0.13 12.5 4.5 0.39 11.0 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function DUF29 Rhodanese PF00581.20 EJP68939.1 - 4.9e-12 46.3 0.0 1e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain CwfJ_C_2 PF04676.14 EJP68940.1 - 2.7e-14 53.9 1.6 5.4e-14 52.9 1.6 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EJP68940.1 - 6.3e-14 51.9 0.0 1.5e-11 44.2 0.0 2.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DRIM PF07539.12 EJP68941.1 - 4e-194 646.5 4.4 1.4e-193 644.7 3.9 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.22 EJP68941.1 - 2.2e-06 27.4 1.4 1.4 9.3 0.0 7.5 6 0 0 6 6 6 1 HEAT repeat RYDR_ITPR PF01365.21 EJP68941.1 - 0.093 12.1 0.6 0.61 9.5 0.0 2.5 2 0 0 2 2 2 0 RIH domain Xpo1 PF08389.12 EJP68941.1 - 0.17 11.9 2.6 1.8 8.6 1.4 3.5 2 1 0 2 2 2 0 Exportin 1-like protein HEAT_EZ PF13513.6 EJP68941.1 - 3.2 8.4 9.2 43 4.7 0.0 7.1 9 0 0 9 9 9 0 HEAT-like repeat zf-DNL PF05180.12 EJP68942.1 - 4.9e-27 93.7 0.4 6.7e-27 93.2 0.4 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 EJP68942.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger zf-RING_2 PF13639.6 EJP68942.1 - 0.19 12.1 1.9 0.3 11.4 1.9 1.3 1 0 0 1 1 1 0 Ring finger domain CAP PF00188.26 EJP68943.1 - 6.3e-19 69.0 0.1 7.5e-19 68.8 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SNF5 PF04855.12 EJP68944.1 - 2.6e-92 308.9 0.0 3.3e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EJP68944.1 - 0.0013 18.3 1.8 0.0031 17.1 1.8 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 EJP68944.1 - 0.53 10.1 3.0 0.86 9.4 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Fungal_trans PF04082.18 EJP68945.1 - 7.6e-18 64.5 1.4 7.6e-18 64.5 1.4 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP68945.1 - 8.5e-08 32.2 9.1 1.4e-07 31.5 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.9 EJP68945.1 - 0.074 11.3 61.8 0.13 10.6 61.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugarporin_N PF11471.8 EJP68945.1 - 0.089 12.8 0.8 0.26 11.3 0.8 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Fungal_trans PF04082.18 EJP68946.1 - 1.1e-12 47.5 0.0 2.8e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP68946.1 - 3e-06 27.2 12.7 5.4e-06 26.4 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.9 EJP68946.1 - 3.5 6.1 8.1 5.1 5.5 8.1 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 EJP68946.1 - 4 6.6 11.2 6 6.0 11.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EPL1 PF10513.9 EJP68946.1 - 4.9 7.5 13.6 9.7 6.6 13.6 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Sod_Cu PF00080.20 EJP68949.1 - 2.4e-12 47.2 0.0 3.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3638 PF12340.8 EJP68951.1 - 4.2e-95 317.4 0.3 8.3e-95 316.4 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EJP68951.1 - 1.9e-18 65.5 0.7 6.2e-18 63.9 0.7 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PEP_mutase PF13714.6 EJP68953.1 - 1.4e-58 198.2 2.1 1.7e-58 197.9 2.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2064 PF09837.9 EJP68953.1 - 0.052 13.4 0.8 0.11 12.3 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Glyco_transf_64 PF09258.10 EJP68954.1 - 4e-47 160.6 0.0 5.1e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 EJP68954.1 - 0.00024 21.1 0.0 0.00054 19.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EJP68954.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Gly_transf_sug PF04488.15 EJP68955.1 - 3e-13 50.2 0.2 5.6e-13 49.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EJP68955.1 - 0.021 14.2 3.8 0.91 8.8 0.1 2.4 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EJP68955.1 - 0.063 12.6 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Fungal_trans PF04082.18 EJP68956.1 - 3.5e-10 39.4 0.1 3.7e-09 36.0 0.0 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain Metallophos PF00149.28 EJP68957.1 - 5.5e-09 36.8 0.0 1e-08 35.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase GFO_IDH_MocA PF01408.22 EJP68958.1 - 4.2e-15 56.6 0.0 6.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EJP68958.1 - 0.0029 18.2 0.0 0.0053 17.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 EJP68958.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain AA_permease_2 PF13520.6 EJP68959.1 - 5.9e-80 269.2 28.3 7.5e-80 268.8 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP68959.1 - 5.4e-14 51.6 29.8 8.8e-14 50.9 29.8 1.3 1 0 0 1 1 1 1 Amino acid permease Amnionless PF14828.6 EJP68961.1 - 0.006 15.5 0.0 0.0096 14.8 0.0 1.2 1 0 0 1 1 1 1 Amnionless Podoplanin PF05808.11 EJP68961.1 - 0.039 14.1 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Podoplanin PTP_tm PF18861.1 EJP68961.1 - 0.068 13.2 1.0 0.11 12.4 1.0 1.4 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J CD99L2 PF12301.8 EJP68961.1 - 0.073 13.4 1.3 0.23 11.7 0.9 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 VSP PF03302.13 EJP68961.1 - 4.4 6.1 9.2 3.3 6.5 7.6 1.5 1 1 0 1 1 1 0 Giardia variant-specific surface protein Ndc1_Nup PF09531.10 EJP68962.1 - 3.5 6.2 8.9 4 6.0 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EJP68962.1 - 8.2 5.5 21.5 12 4.9 21.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Selenoprotein_S PF06936.11 EJP68963.1 - 0.002 17.9 0.5 0.0026 17.6 0.5 1.3 1 0 0 1 1 1 1 Selenoprotein S (SelS) Voldacs PF03517.13 EJP68964.1 - 1e-23 84.0 0.1 2.2e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF1910 PF08928.10 EJP68965.1 - 0.14 12.1 0.6 0.33 10.9 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) DUF1996 PF09362.10 EJP68966.1 - 4.4e-83 278.8 0.9 6e-83 278.4 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.13 EJP68966.1 - 0.034 14.5 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase F-box PF00646.33 EJP68967.1 - 0.00058 19.7 0.2 0.0015 18.4 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EJP68967.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.2 2 0 0 2 2 2 0 F-box-like APH PF01636.23 EJP68968.1 - 1.6e-05 25.0 0.0 0.00033 20.6 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family TPR_2 PF07719.17 EJP68969.1 - 1e-05 25.3 0.0 2.9 8.2 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EJP68969.1 - 1.8e-05 24.4 0.0 2.1 8.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.31 EJP68969.1 - 5.6e-05 22.9 0.1 0.00013 21.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_12 PF13424.6 EJP68969.1 - 0.00036 20.7 0.2 0.016 15.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP68969.1 - 0.0092 16.6 0.4 0.22 12.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF630 PF04783.12 EJP68969.1 - 0.066 13.4 0.2 0.39 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF630) DnaJ PF00226.31 EJP68969.1 - 0.068 13.3 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 DnaJ domain UQ_con PF00179.26 EJP68970.1 - 2.9e-50 169.6 0.0 3.5e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ADP_ribosyl_GH PF03747.14 EJP68971.1 - 1.5e-58 198.9 5.2 1.7e-58 198.7 5.2 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase tRNA-synt_1e PF01406.19 EJP68972.1 - 4.8e-115 384.1 0.0 7.8e-115 383.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EJP68972.1 - 3.3e-05 22.8 0.2 0.12 11.1 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EJP68972.1 - 0.0018 18.7 0.4 0.0049 17.3 0.4 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1c PF00749.21 EJP68972.1 - 0.014 14.3 1.6 0.022 13.7 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain ABATE PF07336.11 EJP68972.1 - 0.021 15.5 0.5 0.25 12.0 0.1 2.8 1 1 1 2 2 2 0 Putative stress-induced transcription regulator XRN_M PF17846.1 EJP68972.1 - 0.043 12.8 1.7 2.9 6.7 0.0 2.6 3 0 0 3 3 3 0 Xrn1 helical domain DUF1599 PF07659.11 EJP68972.1 - 0.11 12.9 0.3 0.32 11.5 0.3 1.7 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 GCD14 PF08704.10 EJP68973.1 - 2.9e-66 223.7 0.0 2.9e-66 223.7 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EJP68973.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 EJP68974.1 - 4.4e-16 58.3 0.2 6.6e-16 57.8 0.2 1.3 1 0 0 1 1 1 1 LSM domain zf-3CxxC PF13695.6 EJP68976.1 - 2.8e-17 63.0 5.2 2.8e-17 63.0 5.2 2.4 2 1 0 2 2 2 1 Zinc-binding domain zf-C2H2 PF00096.26 EJP68976.1 - 4.2e-05 23.8 8.1 0.0036 17.7 0.8 4.7 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP68976.1 - 0.0071 17.1 7.5 0.044 14.6 0.9 4.9 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EJP68976.1 - 0.0077 16.0 0.3 0.0077 16.0 0.3 4.3 5 0 0 5 5 5 1 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 EJP68976.1 - 0.015 15.5 8.9 0.022 15.0 2.2 3.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 EJP68976.1 - 0.26 11.8 0.4 0.26 11.8 0.4 5.5 7 0 0 7 7 7 0 Zinc-finger double domain FANCL_C PF11793.8 EJP68976.1 - 1 9.5 8.3 0.13 12.5 1.2 2.6 3 0 0 3 3 3 0 FANCL C-terminal domain zf-C2H2_aberr PF17017.5 EJP68976.1 - 7.2 6.7 14.7 7 6.7 0.8 3.4 2 1 0 3 3 3 0 Aberrant zinc-finger DUF3712 PF12505.8 EJP68977.1 - 1.7e-19 70.3 0.0 5e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Collagen_mid PF15984.5 EJP68978.1 - 4.6e-05 23.3 30.3 0.68 9.7 0.5 10.4 8 2 2 11 11 11 5 Bacterial collagen, middle region NAF PF03822.14 EJP68978.1 - 6.6e-05 23.0 8.2 1.6e+02 2.6 0.0 11.1 12 1 0 12 12 12 0 NAF domain Cullin PF00888.22 EJP68978.1 - 0.00041 19.1 0.7 2.9 6.4 0.0 3.2 3 0 0 3 3 3 3 Cullin family DUF1869 PF08956.10 EJP68978.1 - 0.0059 16.5 0.2 31 4.6 0.0 4.7 6 0 0 6 6 6 0 Domain of unknown function (DUF1869) DUF4477 PF14780.6 EJP68978.1 - 0.13 11.9 13.2 35 4.0 0.0 8.6 12 0 0 12 12 12 0 Domain of unknown function (DUF4477) Adaptin_N PF01602.20 EJP68978.1 - 0.23 10.0 8.7 2.6 6.5 0.1 5.0 3 2 2 5 5 5 0 Adaptin N terminal region Peptidase_S10 PF00450.22 EJP68979.1 - 8.6e-85 285.6 0.4 1.3e-84 285.1 0.4 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase OmpH PF03938.14 EJP68980.1 - 1.4 9.3 40.6 2.6 8.4 1.3 3.3 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) HAUS-augmin3 PF14932.6 EJP68980.1 - 4.5 6.8 21.5 0.96 9.0 14.6 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 FLILHELTA PF10306.9 EJP68981.1 - 0.008 16.6 0.3 0.017 15.5 0.3 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Glyco_hydro_18 PF00704.28 EJP68982.1 - 1e-13 51.7 0.0 2e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 ABC_tran PF00005.27 EJP68983.1 - 7.6e-42 143.1 0.0 3.4e-22 79.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP68983.1 - 3.7e-20 72.7 36.2 1.4e-16 60.9 17.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 EJP68983.1 - 4.4e-07 30.0 0.0 0.017 14.9 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP68983.1 - 7.7e-07 28.8 0.0 0.0089 15.5 0.0 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP68983.1 - 7.8e-05 22.3 0.2 0.0033 17.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP68983.1 - 0.00046 20.5 0.0 0.69 10.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EJP68983.1 - 0.00047 20.6 0.5 1.2 9.5 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EJP68983.1 - 0.00066 19.3 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EJP68983.1 - 0.00068 18.8 0.0 0.027 13.5 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EJP68983.1 - 0.0027 17.0 0.0 0.45 9.7 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 EJP68983.1 - 0.0054 16.5 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EJP68983.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 EJP68983.1 - 0.013 15.4 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 EJP68983.1 - 0.025 15.1 0.1 0.39 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EJP68983.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 EJP68983.1 - 0.075 12.5 0.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EJP68983.1 - 0.12 12.9 1.2 19 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 EJP68983.1 - 0.21 11.2 0.9 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EJP68983.1 - 0.57 10.3 2.7 33 4.6 0.0 3.0 4 0 0 4 4 3 0 AAA domain FLILHELTA PF10306.9 EJP68985.1 - 2e-32 111.4 0.1 2.9e-32 110.9 0.1 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EJP68985.1 - 0.03 14.9 0.1 0.045 14.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) NDK PF00334.19 EJP68986.1 - 2.2e-54 183.1 0.0 2.5e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GATase_2 PF00310.21 EJP68987.1 - 0.024 13.3 0.6 0.29 9.8 0.0 2.4 1 1 2 3 3 3 0 Glutamine amidotransferases class-II ERGIC_N PF13850.6 EJP68987.1 - 0.15 12.4 0.1 62 4.0 0.0 3.5 2 1 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Octopine_DH PF02317.17 EJP68988.1 - 2.4e-42 144.6 0.0 3.4e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_binding_8 PF13450.6 EJP68988.1 - 0.00086 19.5 0.5 0.0023 18.1 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EJP68988.1 - 0.0014 17.8 0.8 0.0026 16.9 0.8 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 EJP68988.1 - 0.0017 18.0 0.9 0.0019 17.9 0.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP68988.1 - 0.0021 17.3 0.3 0.003 16.9 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 EJP68988.1 - 0.0025 18.4 1.7 0.014 16.0 0.9 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EJP68988.1 - 0.003 17.5 0.1 0.0083 16.1 0.1 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 EJP68988.1 - 0.01 16.4 0.1 0.024 15.2 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 EJP68988.1 - 0.018 14.9 0.8 0.42 10.5 0.1 2.3 2 0 0 2 2 2 0 Rossmann-like domain ApbA PF02558.16 EJP68988.1 - 0.042 13.5 0.9 0.073 12.7 0.9 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_31 PF01055.26 EJP68990.1 - 1.7e-139 465.8 7.2 2.4e-139 465.3 7.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EJP68990.1 - 6.1e-26 90.5 0.9 1e-24 86.6 0.3 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EJP68990.1 - 1.4e-06 28.5 2.4 2.9e-06 27.5 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) MS_channel PF00924.18 EJP68991.1 - 3.8e-19 69.0 2.3 6.4e-19 68.3 2.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EJP68991.1 - 0.0012 18.2 0.3 0.003 17.0 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EJP68991.1 - 0.09 12.6 0.7 0.21 11.4 0.7 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EJP68991.1 - 0.11 12.5 0.5 0.29 11.2 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain DUF2985 PF11204.8 EJP68991.1 - 0.18 12.0 0.9 0.58 10.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) HhH-GPD PF00730.25 EJP68992.1 - 3.2e-08 34.0 0.0 7.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EJP68992.1 - 3.4e-05 23.5 0.0 9.8e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Gamma_PGA_hydro PF05908.11 EJP68992.1 - 0.011 15.2 0.8 0.031 13.7 0.0 2.1 2 1 1 3 3 3 0 Poly-gamma-glutamate hydrolase HHH_5 PF14520.6 EJP68992.1 - 0.047 14.3 0.0 0.16 12.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peptidase_A4 PF01828.17 EJP68993.1 - 7.7e-61 205.2 3.9 8.9e-61 205.0 3.9 1.0 1 0 0 1 1 1 1 Peptidase A4 family BRCT PF00533.26 EJP68994.1 - 3.8e-06 27.2 0.0 8.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EJP68994.1 - 5.9e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EJP68994.1 - 0.00019 21.7 0.0 0.00047 20.5 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 EJP68994.1 - 0.0014 18.7 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Aldedh PF00171.22 EJP68995.1 - 5.9e-132 440.4 0.3 7.2e-132 440.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EJP68995.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) TPR_12 PF13424.6 EJP68996.1 - 5.3e-13 49.1 8.3 1.5e-05 25.2 0.4 4.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EJP68996.1 - 2.5e-08 33.5 5.9 0.83 10.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJP68996.1 - 7.1e-08 31.9 3.5 5.8 6.9 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EJP68996.1 - 7.7e-06 25.6 6.2 1.5 9.1 0.1 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EJP68996.1 - 9.9e-06 25.3 1.7 4.3 7.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP68996.1 - 1.2e-05 24.9 0.3 4.9 7.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP68996.1 - 0.00015 21.2 3.9 0.05 13.0 0.3 2.2 1 1 0 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 EJP68996.1 - 0.0021 18.5 5.9 0.16 12.5 0.0 3.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP68996.1 - 0.003 18.2 0.1 1.3 10.1 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP68996.1 - 0.0046 17.6 0.2 3.8 8.2 0.1 3.4 2 2 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP68996.1 - 0.0097 16.1 8.1 1.4 9.2 0.1 4.6 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 PcfK PF14058.6 EJP68996.1 - 0.024 14.9 0.1 0.041 14.2 0.1 1.3 1 0 0 1 1 1 0 PcfK-like protein TPR_11 PF13414.6 EJP68996.1 - 0.078 12.7 0.3 0.98 9.2 0.0 3.0 4 0 0 4 4 4 0 TPR repeat CRISPR_Cas2 PF09827.9 EJP68996.1 - 0.14 12.3 0.0 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 CRISPR associated protein Cas2 TPR_6 PF13174.6 EJP68996.1 - 0.67 10.7 3.4 26 5.8 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_M49 PF03571.15 EJP68997.1 - 1e-181 605.1 0.0 1.4e-181 604.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Lipase_3 PF01764.25 EJP68998.1 - 6e-29 100.7 0.0 8.2e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EJP68998.1 - 0.035 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-LSD1 PF06943.12 EJP68998.1 - 0.041 13.7 0.9 0.074 12.9 0.9 1.4 1 0 0 1 1 1 0 LSD1 zinc finger BTB_3 PF16017.5 EJP68998.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain FAD_binding_4 PF01565.23 EJP68999.1 - 2.5e-16 59.7 6.4 1.5e-09 37.7 3.8 2.9 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.12 EJP68999.1 - 7.8e-09 35.5 3.6 1.5e-08 34.6 3.6 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EJP68999.1 - 0.14 11.6 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FTR1 PF03239.14 EJP69001.1 - 6.6e-79 265.3 8.1 8.1e-79 265.0 8.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family MHC2-interact PF09307.10 EJP69001.1 - 0.23 11.5 0.0 0.47 10.5 0.0 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting Cu-oxidase_3 PF07732.15 EJP69002.1 - 4.2e-46 155.8 3.3 5.6e-43 145.7 1.5 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EJP69002.1 - 2.3e-44 150.5 8.2 5.6e-40 136.3 0.2 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EJP69002.1 - 2.2e-41 141.6 1.6 2.1e-35 122.2 0.2 3.4 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 EJP69002.1 - 0.00078 19.5 0.0 5.6 7.1 0.0 3.6 3 1 0 3 3 3 2 Cupredoxin-like domain Sulfotransfer_4 PF17784.1 EJP69003.1 - 1.4e-57 195.0 0.1 1.7e-57 194.8 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EJP69003.1 - 0.0001 22.8 1.2 0.11 12.9 0.2 2.8 1 1 0 2 2 2 2 Sulfotransferase family Acetyltransf_1 PF00583.25 EJP69004.1 - 1.1e-06 28.9 0.0 1.4e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP69004.1 - 0.0048 17.3 0.0 0.0076 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 EJP69004.1 - 0.032 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_10 PF13673.7 EJP69004.1 - 0.037 13.9 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 EJP69006.1 - 2.2e-08 34.1 5.9 5e-08 32.9 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP69006.1 - 5.2e-07 28.8 0.6 8.7e-07 28.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 EJP69007.1 - 1.7e-50 169.5 12.7 3.5e-12 46.8 0.2 6.0 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP69007.1 - 4.5e-29 100.5 10.5 2.2e-11 44.0 0.0 7.0 6 1 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 EJP69007.1 - 1.8e-26 91.4 16.8 6e-06 26.5 0.0 10.1 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 EJP69007.1 - 2.1e-22 78.9 15.7 1.9e-07 31.2 0.4 6.5 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP69007.1 - 2.3e-22 76.6 7.9 0.0031 17.9 0.0 10.6 10 0 0 10 10 10 5 Ankyrin repeat zf-UBR PF02207.20 EJP69007.1 - 0.032 14.4 5.5 0.13 12.5 5.5 2.1 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF1612 PF07756.12 EJP69007.1 - 0.09 13.0 0.1 0.42 10.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1612) F-box-like PF12937.7 EJP69008.1 - 0.0005 19.9 0.1 0.00087 19.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 EJP69008.1 - 0.14 12.8 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) SLT PF01464.20 EJP69010.1 - 0.07 12.8 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 Transglycosylase SLT domain SOG2 PF10428.9 EJP69010.1 - 1.8 7.7 12.7 2.5 7.2 12.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SIL1 PF16782.5 EJP69011.1 - 7.7e-08 31.9 0.0 1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 DUF3515 PF12028.8 EJP69011.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3515) SET PF00856.28 EJP69012.1 - 2.1e-08 34.7 0.0 1.1e-07 32.5 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EJP69012.1 - 7.5e-08 32.3 10.1 7.5e-08 32.3 10.1 2.1 2 0 0 2 2 2 1 MYND finger TraI PF07057.11 EJP69012.1 - 0.077 13.1 0.0 5.9 7.0 0.0 2.9 2 0 0 2 2 2 0 DNA helicase TraI RNase_T PF00929.24 EJP69013.1 - 2.9e-07 31.2 0.0 1.6e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 Exonuclease TRP PF06011.12 EJP69014.1 - 2.6e-36 125.3 25.5 2.8e-35 121.9 25.5 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EJP69014.1 - 1.8e-26 93.2 0.0 2.9e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 ML-like domain HATPase_c_3 PF13589.6 EJP69015.1 - 4.4e-12 46.0 0.1 8.7e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EJP69015.1 - 2.5e-08 34.4 0.2 2e-07 31.5 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EJP69015.1 - 2.7e-07 30.3 0.0 4.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DMRL_synthase PF00885.19 EJP69016.1 - 7.7e-59 197.6 0.2 1.1e-58 197.0 0.2 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF3177 PF11375.8 EJP69016.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3177) Cation_efflux PF01545.21 EJP69018.1 - 5e-21 75.3 12.2 6.7e-21 74.9 12.2 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EJP69018.1 - 1e-05 25.6 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PI3_PI4_kinase PF00454.27 EJP69019.1 - 2.1e-39 135.8 0.0 7.8e-37 127.4 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EJP69019.1 - 5.8e-24 84.5 0.0 1.3e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.26 EJP69020.1 - 2.2e-29 102.3 0.1 4.9e-29 101.2 0.1 1.5 1 1 0 1 1 1 1 Proteasome subunit YTH PF04146.15 EJP69021.1 - 4.7e-59 199.0 0.1 8e-59 198.3 0.1 1.4 1 0 0 1 1 1 1 YT521-B-like domain HSP20 PF00011.21 EJP69022.1 - 8.1e-17 61.3 0.6 6.9e-11 42.2 0.0 2.6 3 0 0 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EJP69022.1 - 5.3e-05 22.7 0.0 0.05 13.2 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Rad51 PF08423.11 EJP69023.1 - 1.3e-127 424.3 0.0 1.7e-127 424.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EJP69023.1 - 3.8e-09 36.4 0.0 5.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EJP69023.1 - 2e-08 34.0 0.0 2.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EJP69023.1 - 9.7e-07 29.3 1.4 2.6e-06 27.9 0.3 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EJP69023.1 - 8.1e-06 25.3 0.0 1.7e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EJP69023.1 - 0.0065 15.8 0.0 0.026 13.8 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 EJP69023.1 - 0.043 13.8 0.2 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain AAA_24 PF13479.6 EJP69023.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 EJP69023.1 - 0.2 10.8 0.2 0.99 8.5 0.1 1.9 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.8 EJP69024.1 - 3.5e-137 458.3 0.0 4.9e-137 457.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Vps26 PF03643.15 EJP69025.1 - 1.3e-128 427.8 0.8 1.5e-128 427.6 0.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EJP69025.1 - 0.00069 19.7 1.0 1.1 9.4 0.0 3.6 1 1 3 4 4 4 2 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 EJP69025.1 - 0.066 13.3 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Ribosomal_L6 PF00347.23 EJP69026.1 - 9.9e-27 93.4 10.1 5.7e-13 49.4 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4690 PF15756.5 EJP69027.1 - 0.063 13.9 1.4 0.19 12.3 1.4 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 EJP69027.1 - 0.16 12.2 0.3 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 Glycophorin A V-ATPase_H_N PF03224.14 EJP69029.1 - 1e-72 245.2 0.0 1.4e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EJP69029.1 - 2.6e-36 124.3 0.0 1.4e-35 121.9 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 EJP69029.1 - 0.0015 18.8 0.1 0.19 12.1 0.0 3.1 2 0 0 2 2 2 1 HEAT repeats Umbravirus_LDM PF04817.12 EJP69029.1 - 0.13 11.6 0.3 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family Adaptin_N PF01602.20 EJP69029.1 - 0.16 10.5 0.1 0.53 8.8 0.1 1.9 2 1 0 2 2 2 0 Adaptin N terminal region RIX1 PF08167.12 EJP69029.1 - 0.31 10.8 6.7 0.84 9.3 0.0 3.9 2 2 3 5 5 5 0 rRNA processing/ribosome biogenesis GCV_T PF01571.21 EJP69030.1 - 1.8e-80 270.0 0.0 2.4e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EJP69030.1 - 2e-22 78.9 0.4 1e-21 76.6 0.5 2.2 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Aminotran_3 PF00202.21 EJP69031.1 - 3.1e-110 368.6 0.0 3.5e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III AA_permease PF00324.21 EJP69032.1 - 4.8e-105 351.9 42.1 5.7e-105 351.7 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP69032.1 - 1.4e-28 99.9 46.7 1.8e-28 99.6 46.7 1.1 1 0 0 1 1 1 1 Amino acid permease Metallophos PF00149.28 EJP69033.1 - 1.5e-08 35.4 0.7 1.5e-08 35.4 0.7 2.0 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase NST1 PF13945.6 EJP69033.1 - 0.23 11.5 7.5 9.1 6.3 2.6 3.2 3 0 0 3 3 3 0 Salt tolerance down-regulator PBP1_TM PF14812.6 EJP69033.1 - 0.61 10.5 22.7 0.73 10.2 2.2 3.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SR-25 PF10500.9 EJP69033.1 - 0.87 9.2 22.0 1.7 8.2 0.4 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein YL1 PF05764.13 EJP69033.1 - 1.2 9.2 18.5 0.77 9.8 3.2 2.4 2 1 0 2 2 2 0 YL1 nuclear protein AP3D1 PF06375.11 EJP69033.1 - 7.8 6.7 26.6 5.5 7.2 0.5 3.4 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 DUF4604 PF15377.6 EJP69033.1 - 9.2 6.7 25.3 3 8.2 4.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) DUF1765 PF08578.10 EJP69035.1 - 4.2e-42 143.5 9.0 5.6e-42 143.2 8.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) PGM_PMM_I PF02878.16 EJP69036.1 - 1.5e-16 60.4 0.2 8.3e-08 32.0 0.0 3.7 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EJP69036.1 - 2.5e-11 43.6 1.0 2e-10 40.7 1.2 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 EJP69036.1 - 0.00038 21.0 1.3 0.016 15.8 1.0 3.5 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EJP69036.1 - 0.0089 16.2 0.0 0.031 14.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 6PGD PF00393.19 EJP69037.1 - 3.2e-128 427.1 0.0 3.9e-128 426.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EJP69037.1 - 6.4e-50 169.4 0.0 9.9e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EJP69037.1 - 0.05 13.8 0.2 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ANT PF03374.14 EJP69037.1 - 0.1 12.9 0.1 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain F420_oxidored PF03807.17 EJP69037.1 - 0.12 13.0 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sas6_CC PF18594.1 EJP69037.1 - 0.17 11.7 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain ABC_tran PF00005.27 EJP69038.1 - 6.8e-36 123.8 0.0 3.9e-18 66.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP69038.1 - 9.9e-15 54.9 12.6 1.8e-10 40.9 2.7 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region Dynamin_N PF00350.23 EJP69038.1 - 1.4e-05 25.2 0.1 0.0018 18.4 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 EJP69038.1 - 2.7e-05 24.6 0.1 0.39 11.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EJP69038.1 - 5.2e-05 23.3 0.1 0.099 12.7 0.2 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EJP69038.1 - 0.0005 19.7 0.2 0.24 11.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP69038.1 - 0.00087 19.2 0.0 2.1 8.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EJP69038.1 - 0.0033 17.7 0.4 1.2 9.4 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EJP69038.1 - 0.061 13.1 7.4 0.055 13.3 0.3 3.0 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system ResB PF05140.14 EJP69038.1 - 0.15 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 ResB-like family AAA_PrkA PF08298.11 EJP69038.1 - 0.17 10.8 0.0 12 4.6 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain AAA_23 PF13476.6 EJP69038.1 - 1.1 9.7 8.7 24 5.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain Elongin_A PF06881.11 EJP69039.1 - 3.9e-28 98.0 0.5 3.9e-28 98.0 0.5 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TFIIF_alpha PF05793.12 EJP69039.1 - 1.5 7.3 8.9 2.5 6.6 8.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Dicty_REP PF05086.12 EJP69039.1 - 2.6 5.9 4.9 3.9 5.3 4.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ubiquitin PF00240.23 EJP69040.1 - 3e-26 91.0 0.3 3.4e-26 90.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EJP69040.1 - 2.4e-15 56.1 0.4 2.6e-15 56.0 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EJP69040.1 - 0.00097 19.5 0.1 0.0014 19.0 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EJP69040.1 - 0.024 14.6 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EJP69040.1 - 0.03 14.3 0.6 2.3 8.4 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain ThiS PF02597.20 EJP69040.1 - 0.058 14.0 0.1 0.14 12.8 0.1 1.6 1 1 0 1 1 1 0 ThiS family Rad60-SLD_2 PF13881.6 EJP69040.1 - 0.14 12.3 0.0 0.39 10.8 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Band_7 PF01145.25 EJP69041.1 - 4.4e-21 75.7 2.7 6.7e-21 75.1 2.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_11 PF08241.12 EJP69042.1 - 3.2e-12 46.9 0.0 6.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP69042.1 - 3e-06 27.8 0.0 8.2e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP69042.1 - 0.00059 19.7 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP69042.1 - 0.021 15.6 0.0 0.065 14.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain VGCC_beta4Aa_N PF12052.8 EJP69042.1 - 0.12 12.5 0.1 0.49 10.5 0.1 2.1 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Ubie_methyltran PF01209.18 EJP69042.1 - 0.25 10.6 0.0 0.48 9.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SUI1 PF01253.22 EJP69043.1 - 9e-24 83.8 0.3 9e-24 83.8 0.3 2.1 3 0 0 3 3 3 1 Translation initiation factor SUI1 TnpV PF14198.6 EJP69043.1 - 0.07 13.1 0.5 0.12 12.4 0.5 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Img2 PF05046.14 EJP69043.1 - 0.087 13.1 0.0 0.22 11.8 0.0 1.8 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) MscS_TM PF12794.7 EJP69043.1 - 0.24 10.2 2.6 0.3 9.9 2.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nbl1_Borealin_N PF10444.9 EJP69044.1 - 1.1e-20 73.0 0.8 1.9e-20 72.2 0.8 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 EJP69045.1 - 5.6e-27 94.5 0.4 1.1e-26 93.6 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EJP69045.1 - 4.1e-13 49.9 0.2 5.5e-13 49.5 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EJP69045.1 - 9.3e-09 35.4 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EJP69045.1 - 0.011 15.6 1.4 0.036 14.0 1.4 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Sybindin PF04099.12 EJP69046.1 - 1.4e-51 174.2 0.0 1.6e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EJP69046.1 - 4.4e-07 30.1 0.0 6.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RNA_pol_Rpb4 PF03874.16 EJP69047.1 - 8.5e-26 90.7 5.1 1.1e-25 90.4 5.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 TFR_dimer PF04253.15 EJP69047.1 - 0.055 13.6 0.4 0.6 10.2 0.4 2.2 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain Spexin PF15171.6 EJP69047.1 - 0.083 13.1 1.1 0.12 12.6 0.2 1.7 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin CHD5 PF04420.14 EJP69047.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 CHD5-like protein dsDNA_bind PF01984.20 EJP69047.1 - 0.21 11.8 2.9 0.22 11.8 0.2 2.2 2 1 0 2 2 2 0 Double-stranded DNA-binding domain DUF4328 PF14219.6 EJP69048.1 - 0.00031 20.4 0.2 0.00064 19.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) CcmD PF04995.14 EJP69048.1 - 0.042 13.9 0.7 0.087 12.9 0.7 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FixQ PF05545.11 EJP69048.1 - 0.19 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Gemini_mov PF01708.16 EJP69048.1 - 0.95 9.3 6.7 1.2 8.9 0.2 3.1 2 2 0 2 2 2 0 Geminivirus putative movement protein QWRF PF04484.12 EJP69048.1 - 9.5 5.9 11.7 15 5.2 11.7 1.4 1 0 0 1 1 1 0 QWRF family CPL PF08144.11 EJP69049.1 - 1.3e-42 145.5 0.2 5.7e-40 137.0 0.0 4.0 4 1 0 4 4 4 1 CPL (NUC119) domain UPF0122 PF04297.14 EJP69049.1 - 0.42 10.9 3.2 1.4 9.2 0.0 2.9 3 0 0 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like RWD PF05773.22 EJP69050.1 - 7.2e-22 77.9 0.0 1.2e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EJP69050.1 - 3.4e-05 24.2 9.0 4e-05 24.0 7.7 1.8 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF2852 PF11014.8 EJP69050.1 - 0.0032 17.6 4.5 0.0047 17.1 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2852) Muted PF14942.6 EJP69050.1 - 5 7.5 12.4 0.63 10.4 2.6 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TPR_12 PF13424.6 EJP69051.1 - 9.1e-14 51.5 1.7 4.8e-06 26.8 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP69051.1 - 1.3e-10 41.7 7.0 0.0023 18.4 0.1 4.2 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP69051.1 - 9.1e-10 37.9 2.6 0.012 15.7 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJP69051.1 - 8.4e-09 35.9 4.8 0.00023 21.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP69051.1 - 2.9e-08 33.2 1.5 0.44 10.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP69051.1 - 7.7e-08 32.5 11.0 0.58 11.1 0.1 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EJP69051.1 - 8.2e-08 31.9 0.0 0.037 14.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP69051.1 - 2.8e-07 30.7 0.0 0.17 12.1 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EJP69051.1 - 2.1e-06 27.4 2.4 2.1 8.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP69051.1 - 6.8e-06 25.7 1.5 0.061 12.7 0.0 2.6 2 1 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 EJP69051.1 - 4e-05 23.2 0.0 5.3 7.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJP69051.1 - 0.0024 17.5 0.2 6 6.6 0.0 4.1 4 0 0 4 4 4 1 TPR repeat TPR_6 PF13174.6 EJP69051.1 - 0.0091 16.6 4.7 14 6.5 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EJP69051.1 - 0.45 11.3 10.8 4.1 8.3 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EJP69051.1 - 2.5 8.3 10.1 3.2 8.0 0.2 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Lum_binding PF00677.17 EJP69052.1 - 2.2e-45 152.6 0.3 2.3e-22 78.8 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.15 EJP69053.1 - 1.4e-25 90.3 0.0 2.3e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EJP69053.1 - 0.0021 18.4 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF3662 PF12401.8 EJP69053.1 - 0.057 13.8 0.0 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) Methyltransf_25 PF13649.6 EJP69054.1 - 5.6e-11 43.0 0.1 1.7e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EJP69054.1 - 8.3e-10 38.5 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EJP69054.1 - 9.8e-10 38.4 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP69054.1 - 3.9e-07 30.6 0.0 1e-06 29.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EJP69054.1 - 6.6e-06 25.3 0.1 8.4e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 EJP69054.1 - 3.4e-05 23.7 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EJP69054.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP69054.1 - 0.00073 20.2 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJP69054.1 - 0.0013 18.4 0.1 0.0024 17.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EJP69054.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 EJP69054.1 - 0.008 16.0 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 EJP69054.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EJP69054.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ribosomal_S8e PF01201.22 EJP69055.1 - 3.1e-46 156.9 5.2 5.5e-46 156.1 4.7 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L21p PF00829.21 EJP69056.1 - 1.7e-13 50.7 0.0 2.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 EJP69057.1 - 1e-46 159.4 0.0 1.6e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69057.1 - 3.4e-21 75.7 0.0 4.9e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP69057.1 - 0.0073 15.7 0.0 0.026 13.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EJP69057.1 - 0.033 14.1 0.3 0.68 9.8 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family PsaA_PsaB PF00223.19 EJP69057.1 - 0.087 11.0 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein RIO1 PF01163.22 EJP69057.1 - 0.11 12.1 0.3 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 RIO1 family MFS_1 PF07690.16 EJP69058.1 - 1.4e-36 126.1 35.4 2.4e-36 125.4 35.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 EJP69058.1 - 8.4e-13 47.9 1.5 1.6e-12 47.0 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M20 PF01546.28 EJP69059.1 - 3.5e-27 95.5 0.2 5.4e-27 94.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EJP69059.1 - 8.7e-05 22.3 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 EJP69059.1 - 0.00086 19.2 0.1 0.002 18.0 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain NAD_binding_10 PF13460.6 EJP69062.1 - 7.4e-07 29.2 0.2 1.2e-06 28.5 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EJP69062.1 - 3.9e-06 26.6 0.0 6.6e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Per1 PF04080.13 EJP69063.1 - 1.9e-105 352.2 8.5 2.3e-105 352.0 8.5 1.1 1 0 0 1 1 1 1 Per1-like family Ceramidase PF05875.12 EJP69063.1 - 2.4 7.5 11.3 14 5.0 8.6 2.7 1 1 0 2 2 2 0 Ceramidase MerC PF03203.14 EJP69063.1 - 3.2 8.2 9.8 7.3 7.1 5.2 2.9 2 1 1 3 3 3 0 MerC mercury resistance protein HLH PF00010.26 EJP69064.1 - 3e-13 49.5 0.2 5.1e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 EJP69065.1 - 1 8.9 7.0 0.3 10.7 1.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Aldedh PF00171.22 EJP69066.1 - 4.9e-107 358.3 0.2 6e-107 358.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoD PF09423.10 EJP69067.1 - 7.6e-06 25.2 0.3 0.0043 16.1 0.0 2.8 3 0 0 3 3 3 2 PhoD-like phosphatase Pkinase PF00069.25 EJP69068.1 - 5.5e-17 62.0 0.0 7.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69068.1 - 2.4e-16 59.8 0.0 5.3e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP69068.1 - 1.9e-05 24.7 0.5 0.023 14.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family PSI_PSAK PF01241.18 EJP69068.1 - 0.00077 19.4 0.0 0.93 9.5 0.0 2.4 2 0 0 2 2 2 2 Photosystem I psaG / psaK RIO1 PF01163.22 EJP69068.1 - 0.021 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EJP69068.1 - 0.1 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIF_beta_N PF17683.1 EJP69069.1 - 6.4e-31 107.8 0.1 2.1e-30 106.2 0.0 1.9 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EJP69069.1 - 1.5e-28 98.7 0.1 2.8e-28 97.8 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain HAD PF12710.7 EJP69069.1 - 1.1e-11 45.5 5.7 5.6e-11 43.2 5.7 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP69069.1 - 0.0011 19.3 1.8 0.0029 17.9 1.8 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tau95 PF09734.9 EJP69069.1 - 0.0096 16.7 0.2 0.018 15.9 0.2 1.5 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain EspB_PE PF18625.1 EJP69070.1 - 0.0091 16.4 1.5 0.029 14.8 0.2 2.2 3 0 0 3 3 3 1 ESX-1 secreted protein B PE domain Mod_r PF07200.13 EJP69070.1 - 0.018 15.1 2.2 0.17 12.0 0.2 2.3 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Syntaxin-6_N PF09177.11 EJP69070.1 - 0.026 15.1 0.4 0.17 12.5 0.1 2.5 2 2 0 2 2 2 0 Syntaxin 6, N-terminal TolA_bind_tri PF16331.5 EJP69070.1 - 0.035 14.2 0.2 0.035 14.2 0.2 2.3 3 0 0 3 3 3 0 TolA binding protein trimerisation NPV_P10 PF05531.12 EJP69070.1 - 0.099 13.1 1.9 7.2 7.2 0.0 3.2 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.10 EJP69070.1 - 0.52 10.1 3.7 22 5.0 0.0 3.7 3 1 1 4 4 4 0 DASH complex subunit Dam1 DASH_Dad2 PF08654.10 EJP69070.1 - 0.9 10.0 4.1 65 4.0 0.1 3.6 2 1 2 4 4 4 0 DASH complex subunit Dad2 Cu_amine_oxid PF01179.20 EJP69071.1 - 1.1e-159 531.7 0.0 1.7e-159 531.1 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain CHORD PF04968.12 EJP69071.1 - 5.7e-47 158.3 20.1 7.9e-25 87.4 5.3 2.9 3 0 0 3 3 3 2 CHORD CS PF04969.16 EJP69071.1 - 7.7e-10 39.7 0.0 1.7e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 CS domain Cu_amine_oxidN2 PF02727.16 EJP69071.1 - 0.00085 19.5 0.1 0.0019 18.4 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 EJP69071.1 - 0.015 15.7 0.5 0.035 14.5 0.0 1.8 2 0 0 2 2 2 0 Copper amine oxidase, N3 domain DUF3602 PF12223.8 EJP69072.1 - 3.8e-23 81.9 4.8 3.8e-23 81.9 4.8 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Sporozoite_P67 PF05642.11 EJP69072.1 - 0.27 9.3 2.7 0.3 9.1 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATG22 PF11700.8 EJP69073.1 - 6.8e-177 588.9 15.4 9.4e-175 581.8 10.9 2.0 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like TMEM132D_C PF15706.5 EJP69073.1 - 0.18 11.6 0.8 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term BAH PF01426.18 EJP69074.1 - 0.00044 20.1 0.0 0.00088 19.1 0.0 1.5 1 1 0 1 1 1 1 BAH domain PHD PF00628.29 EJP69074.1 - 0.0021 17.9 1.4 0.0052 16.7 1.4 1.6 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 EJP69074.1 - 0.09 13.0 0.7 0.24 11.6 0.7 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 EJP69074.1 - 0.12 12.6 0.4 0.3 11.4 0.4 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain F_actin_cap_B PF01115.17 EJP69075.1 - 5.4e-102 340.5 0.0 6.3e-102 340.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Epimerase PF01370.21 EJP69076.1 - 1.3e-16 60.8 0.0 1.7e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EJP69076.1 - 1.3e-08 34.3 0.0 1.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EJP69076.1 - 0.0093 15.0 0.0 0.039 13.0 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EJP69076.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 KR domain CBS PF00571.28 EJP69078.1 - 6.3e-07 29.7 0.0 0.03 14.8 0.0 3.3 2 1 1 3 3 3 3 CBS domain Maf_N PF08383.11 EJP69078.1 - 0.23 11.3 0.3 0.23 11.3 0.3 1.8 2 0 0 2 2 2 0 Maf N-terminal region Mito_carr PF00153.27 EJP69079.1 - 5.7e-49 164.0 5.0 5.6e-19 67.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.29 EJP69080.1 - 1.1e-39 136.5 0.0 2e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJP69080.1 - 5e-18 65.8 0.1 5e-18 65.8 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SRP-alpha_N PF04086.13 EJP69080.1 - 0.083 12.8 29.3 0.024 14.6 23.4 2.6 2 1 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_C98 PF15499.6 EJP69080.1 - 2.3 7.6 11.5 0.14 11.6 0.7 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Glyco_transf_22 PF03901.17 EJP69081.1 - 3.5e-38 131.9 15.4 5.1e-38 131.4 15.4 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PP2C PF00481.21 EJP69082.1 - 1.8e-54 185.1 0.0 5.9e-54 183.4 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.7 EJP69082.1 - 1.1e-37 127.4 61.6 0.00039 20.8 0.0 11.7 10 1 1 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EJP69082.1 - 2.1e-37 126.7 54.0 6.7e-08 32.2 1.5 9.3 3 3 6 10 10 10 10 Leucine rich repeat Guanylate_cyc PF00211.20 EJP69082.1 - 1.1e-28 100.1 0.0 8.9e-28 97.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 EJP69082.1 - 9.4e-20 70.1 0.2 2.6e-19 68.6 0.2 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_6 PF13516.6 EJP69082.1 - 0.00097 19.0 42.3 3.4 8.0 0.3 11.9 13 0 0 13 13 13 2 Leucine Rich repeat LRR_9 PF14580.6 EJP69082.1 - 0.032 13.8 18.3 0.18 11.3 0.4 4.4 2 1 2 4 4 4 0 Leucine-rich repeat LRR_1 PF00560.33 EJP69082.1 - 0.066 13.8 51.2 20 6.2 0.0 15.6 17 2 0 17 17 17 0 Leucine Rich Repeat RA PF00788.23 EJP69082.1 - 0.071 13.7 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain DLH PF01738.18 EJP69084.1 - 9.7e-06 25.3 0.2 0.00024 20.7 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EJP69084.1 - 7.9e-05 23.4 0.0 0.0001 23.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP69084.1 - 0.05 12.9 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Holin_BhlA PF10960.8 EJP69086.1 - 0.019 14.9 1.8 0.51 10.3 0.2 2.3 2 0 0 2 2 2 0 BhlA holin family Tmemb_9 PF05434.11 EJP69086.1 - 0.024 14.5 0.3 0.024 14.5 0.3 1.5 2 0 0 2 2 2 0 TMEM9 Antigen_Bd37 PF11641.8 EJP69086.1 - 0.083 12.4 1.7 0.097 12.2 1.7 1.1 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein PPP1R35_C PF15503.6 EJP69086.1 - 0.15 11.9 4.5 0.19 11.6 4.5 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Cytochrom_B562 PF07361.11 EJP69086.1 - 0.16 12.6 10.7 0.58 10.8 1.3 2.0 1 1 1 2 2 2 0 Cytochrome b562 TBCA PF02970.16 EJP69086.1 - 0.48 10.8 11.4 0.45 10.9 2.7 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A Sec16_N PF12935.7 EJP69086.1 - 0.52 10.4 9.0 0.62 10.2 9.0 1.0 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Alpha-amylase PF00128.24 EJP69088.1 - 3.8e-118 394.9 0.2 7e-118 394.0 0.2 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EJP69088.1 - 1.9e-08 34.3 0.0 4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 EJP69088.1 - 0.0026 18.2 0.0 0.0072 16.8 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain SpuA_C PF18033.1 EJP69088.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 SpuA C-terminal Dus PF01207.17 EJP69089.1 - 4.4e-31 108.1 0.2 8.7e-22 77.6 0.0 3.2 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) IBR PF01485.21 EJP69090.1 - 4.8e-06 26.7 41.4 0.0015 18.7 4.7 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain DUF719 PF05334.13 EJP69090.1 - 0.4 10.9 0.1 0.4 10.9 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF719) Nup54_57_C PF18570.1 EJP69090.1 - 0.85 9.3 5.5 2.8 7.6 0.7 3.1 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Tugs PF17840.1 EJP69090.1 - 2 8.7 10.2 5.5 7.3 1.8 3.8 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain FAA_hydrolase PF01557.18 EJP69091.1 - 1.8e-65 220.7 0.0 2.1e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PNP_UDP_1 PF01048.20 EJP69092.1 - 3e-11 43.0 0.0 5.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_hydro_31 PF01055.26 EJP69093.1 - 5.8e-150 500.3 8.3 8e-150 499.9 8.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EJP69093.1 - 2.2e-32 111.7 0.0 4.2e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EJP69093.1 - 2.4e-12 47.0 0.4 1.1e-11 44.9 0.4 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Rieske PF00355.26 EJP69094.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain MFS_1 PF07690.16 EJP69096.1 - 1.3e-37 129.6 37.1 1.8e-37 129.1 37.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP69096.1 - 4.9e-12 45.1 9.8 7.6e-12 44.4 9.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EJP69096.1 - 1.3e-08 34.2 5.8 1.3e-08 34.2 5.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Cupin_5 PF06172.11 EJP69097.1 - 9.8e-36 123.0 0.1 1.3e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Cupin_5 PF06172.11 EJP69099.1 - 3.1e-49 166.7 0.0 3.7e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) TetR_C_22 PF17928.1 EJP69099.1 - 0.16 12.3 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PWI PF01480.17 EJP69100.1 - 1.4e-14 54.1 0.2 2.8e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 PWI domain Ribosomal_S21 PF01165.20 EJP69101.1 - 4.1e-08 32.8 2.1 6.6e-08 32.2 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 DUF2464 PF10240.9 EJP69101.1 - 0.31 10.6 1.1 0.41 10.2 1.1 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 Totivirus_coat PF05518.11 EJP69101.1 - 6.9 4.6 9.6 8 4.4 9.6 1.2 1 0 0 1 1 1 0 Totivirus coat protein PAD PF03068.15 EJP69102.1 - 2.8e-112 375.5 0.1 1.9e-111 372.8 0.1 1.9 1 1 0 1 1 1 1 Protein-arginine deiminase (PAD) P3A PF08727.11 EJP69102.1 - 0.059 12.8 0.2 0.14 11.5 0.2 1.6 1 0 0 1 1 1 0 Poliovirus 3A protein like HAUS6_N PF14661.6 EJP69103.1 - 4.1e-56 190.1 0.3 4.1e-56 190.1 0.3 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus GST_C PF00043.25 EJP69104.1 - 5.9e-08 32.8 0.0 1.2e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP69104.1 - 3.8e-07 30.2 0.0 8.1e-07 29.2 0.0 1.5 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EJP69104.1 - 3.8e-06 27.1 0.0 1.1e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EJP69104.1 - 6e-06 26.6 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP69104.1 - 6.4e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP69104.1 - 0.00046 20.2 0.6 0.0013 18.7 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF4419 PF14388.6 EJP69105.1 - 5.4e-96 321.6 0.0 6.4e-96 321.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Mannitol_dh_C PF08125.13 EJP69106.1 - 1.9e-38 132.3 0.1 3e-38 131.7 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EJP69106.1 - 7.8e-19 68.3 0.3 2.8e-18 66.5 0.0 2.0 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 EJP69106.1 - 0.0023 17.5 0.4 0.014 15.0 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF445 PF04286.12 EJP69106.1 - 0.047 13.5 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PGI PF00342.19 EJP69107.1 - 1.6e-225 749.3 0.6 1.9e-225 749.1 0.6 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 EJP69108.1 - 1.1e-68 231.5 0.0 1.5e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69108.1 - 1.4e-32 113.0 0.0 2e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EJP69108.1 - 7.4e-09 36.2 0.2 2e-08 34.8 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EJP69108.1 - 3.6e-05 22.9 0.0 5.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 EJP69108.1 - 0.0021 18.3 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EJP69108.1 - 0.028 13.7 0.0 0.08 12.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EJP69108.1 - 0.099 12.3 0.1 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EJP69108.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Coatomer_WDAD PF04053.14 EJP69109.1 - 2.7e-177 590.3 0.0 8.9e-177 588.6 0.0 1.8 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 EJP69109.1 - 3.1e-36 122.7 12.0 4.7e-06 27.2 0.2 9.8 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP69109.1 - 1.2e-07 31.9 0.1 2.6 8.4 0.0 6.3 3 2 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP69109.1 - 4.7e-05 22.2 2.4 0.12 11.0 0.0 4.0 1 1 3 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EJP69109.1 - 0.014 15.4 0.0 12 6.0 0.0 3.8 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF1681 PF07933.14 EJP69110.1 - 1.3e-54 183.9 0.0 1.9e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) FAM104 PF15434.6 EJP69110.1 - 1.6 9.3 6.4 0.37 11.4 1.4 2.1 2 0 0 2 2 2 0 Family 104 SR-25 PF10500.9 EJP69110.1 - 6.3 6.3 14.4 0.61 9.7 5.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Acyltransf_C PF16076.5 EJP69111.1 - 0.042 13.9 3.3 0.16 12.1 0.0 2.4 2 0 0 2 2 2 0 Acyltransferase C-terminus CP_ATPgrasp_2 PF14403.6 EJP69111.1 - 0.057 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Vfa1 PF08432.10 EJP69111.1 - 0.099 13.0 6.2 0.11 12.9 1.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Radical_SAM PF04055.21 EJP69112.1 - 5.5e-09 36.6 0.0 8.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EJP69112.1 - 0.00043 20.6 0.0 0.00069 19.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EJP69112.1 - 0.071 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Apolipoprotein PF01442.18 EJP69113.1 - 9.4e-05 22.4 2.7 0.0003 20.7 2.7 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EJP69113.1 - 0.0054 16.8 1.7 0.013 15.6 1.7 1.6 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) ATP-synt_B PF00430.18 EJP69113.1 - 0.0085 16.2 5.6 0.015 15.4 5.6 1.4 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) YtxH PF12732.7 EJP69113.1 - 0.34 11.5 4.6 20 5.8 4.6 2.6 1 1 0 1 1 1 0 YtxH-like protein HK97-gp10_like PF04883.12 EJP69113.1 - 1.9 9.5 8.2 36 5.4 5.5 3.4 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component LEA_4 PF02987.16 EJP69113.1 - 3.4 7.8 7.6 0.57 10.3 1.1 2.8 2 1 1 3 3 3 0 Late embryogenesis abundant protein DUF883 PF05957.13 EJP69113.1 - 8.2 7.1 13.4 0.31 11.7 4.5 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) RSN1_7TM PF02714.15 EJP69114.1 - 7.3e-80 268.2 28.4 7.3e-80 268.2 28.4 2.5 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EJP69114.1 - 3.9e-43 146.9 1.4 3.9e-43 146.9 1.4 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EJP69114.1 - 1.8e-35 122.8 0.1 2.8e-35 122.1 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EJP69114.1 - 1.2e-30 105.5 0.8 3.1e-30 104.2 0.8 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF5409 PF17421.2 EJP69114.1 - 0.14 12.9 3.1 10 6.9 0.0 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5409) Acetyltransf_10 PF13673.7 EJP69115.1 - 2.9e-09 36.9 0.0 1e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP69115.1 - 3e-09 37.1 0.0 5.1e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP69115.1 - 1.9e-07 31.4 0.0 5.3e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP69115.1 - 3.5e-05 23.9 0.0 0.0031 17.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EJP69115.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Ion_trans_N PF08412.10 EJP69116.1 - 0.025 14.2 0.1 0.07 12.7 0.1 1.7 1 0 0 1 1 1 0 Ion transport protein N-terminal Mid2 PF04478.12 EJP69116.1 - 0.029 14.2 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor CcmD PF04995.14 EJP69116.1 - 0.63 10.2 2.0 2.2 8.5 2.0 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PBP1_TM PF14812.6 EJP69116.1 - 4.9 7.6 8.0 1.3 9.5 0.5 3.9 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI-PLC-X PF00388.19 EJP69117.1 - 0.00097 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Yip1 PF04893.17 EJP69117.1 - 0.17 11.6 3.5 0.26 11.0 3.5 1.2 1 0 0 1 1 1 0 Yip1 domain Use1 PF09753.9 EJP69117.1 - 0.2 11.3 0.2 0.33 10.6 0.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 Glyco_hydro_18 PF00704.28 EJP69118.1 - 5.6e-24 85.4 1.0 2.6e-23 83.2 1.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 WSC PF01822.19 EJP69119.1 - 1.2e-09 38.3 9.0 1.2e-09 38.3 9.0 2.0 2 0 0 2 2 2 1 WSC domain Podoplanin PF05808.11 EJP69119.1 - 0.00045 20.4 2.4 0.00089 19.4 2.4 1.4 1 0 0 1 1 1 1 Podoplanin Yip1 PF04893.17 EJP69119.1 - 0.04 13.6 0.1 0.057 13.1 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain DUF2207 PF09972.9 EJP69119.1 - 0.091 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5305 PF17231.2 EJP69119.1 - 0.11 11.9 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Apt1 PF10351.9 EJP69119.1 - 1.6 7.5 7.4 2.7 6.7 7.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain An_peroxidase PF03098.15 EJP69120.1 - 1.2e-36 126.4 0.0 1.3e-27 96.7 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EJP69120.1 - 4.7e-10 38.8 0.0 1.3e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.9 EJP69121.1 - 4.8e-61 206.6 9.8 5.5e-40 137.5 2.5 4.0 2 1 1 3 3 3 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Telomere_Sde2_2 PF13297.6 EJP69121.1 - 0.035 13.8 2.0 3.8 7.2 0.1 3.0 2 1 0 2 2 2 0 Telomere stability C-terminal Solute_trans_a PF03619.16 EJP69122.1 - 8.9e-84 281.1 23.5 1.1e-83 280.9 23.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Polysacc_synt_C PF14667.6 EJP69122.1 - 1.4 9.0 16.0 7.5 6.6 3.1 3.1 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain THOC2_N PF16134.5 EJP69123.1 - 9.4e-246 817.4 0.0 1.3e-245 816.9 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EJP69123.1 - 4.7e-91 305.1 0.0 7.7e-91 304.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EJP69123.1 - 4.3e-28 97.2 0.1 9.5e-28 96.1 0.1 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.20 EJP69124.1 - 2.4e-44 151.9 0.0 1.3e-43 149.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP69124.1 - 0.0028 18.3 3.3 0.0056 17.3 3.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.24 EJP69125.1 - 1.4e-45 156.1 8.2 5.4e-45 154.1 8.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP69125.1 - 1.1e-23 83.8 25.5 1.6e-23 83.2 25.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FAM177 PF14774.6 EJP69127.1 - 0.019 15.3 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 FAM177 family DUF3324 PF11797.8 EJP69132.1 - 0.074 13.0 0.1 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) DUF4764 PF15961.5 EJP69133.1 - 7.1 5.2 8.4 0.4 9.3 2.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) HD_3 PF13023.6 EJP69134.1 - 8.4e-48 162.4 0.0 1.1e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EJP69134.1 - 1.1e-08 35.0 0.0 2.5e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme SCIMP PF15050.6 EJP69135.1 - 0.075 13.5 1.8 0.17 12.3 1.8 1.6 1 0 0 1 1 1 0 SCIMP protein DNA_pol3_a_NII PF11490.8 EJP69135.1 - 0.48 10.3 8.5 1.1 9.1 8.5 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II TFIIA PF03153.13 EJP69135.1 - 1.1 9.2 21.1 1.5 8.7 21.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 EJP69135.1 - 1.7 8.8 5.9 3.3 7.9 5.9 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 EJP69135.1 - 4.8 7.2 5.0 3.7 7.5 3.0 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rhodanese PF00581.20 EJP69136.1 - 8.9e-11 42.3 0.0 1.2e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Herpes_UL43 PF05072.13 EJP69136.1 - 0.072 12.2 0.1 0.097 11.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein Myb_DNA-binding PF00249.31 EJP69137.1 - 4.9e-09 36.2 0.0 3.7e-08 33.4 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 EJP69137.1 - 1.3e-07 31.9 0.0 4.2e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.17 EJP69137.1 - 1.8e-07 30.8 4.8 3.6e-07 29.9 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF2054 PF10218.9 EJP69137.1 - 0.027 14.6 0.7 0.064 13.3 0.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) C1_2 PF03107.16 EJP69137.1 - 1 9.7 4.5 2.5 8.5 4.5 1.7 1 0 0 1 1 1 0 C1 domain GalP_UDP_transf PF01087.22 EJP69138.1 - 5e-70 235.7 0.3 4.9e-68 229.2 0.1 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EJP69138.1 - 1.1e-59 200.9 0.0 2.4e-59 199.8 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 EJP69138.1 - 0.00013 22.7 0.0 0.00049 20.8 0.0 2.0 2 0 0 2 2 2 1 HIT domain DUF4921 PF16268.5 EJP69138.1 - 0.0074 15.2 0.1 0.51 9.1 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4921) Erg28 PF03694.13 EJP69139.1 - 6.1e-45 152.1 0.0 7.2e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 Erg28 like protein IMS PF00817.20 EJP69140.1 - 2e-38 131.8 0.0 3.5e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EJP69140.1 - 8.3e-11 42.6 0.0 1.3e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain HHH_5 PF14520.6 EJP69140.1 - 0.012 16.2 0.0 0.033 14.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF726 PF05277.12 EJP69141.1 - 1e-90 304.2 0.2 1.4e-90 303.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) FoP_duplication PF13865.6 EJP69141.1 - 4.2 8.0 7.9 9.1 6.9 7.9 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DENN PF02141.21 EJP69142.1 - 9.6e-56 188.7 0.0 1.5e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 EJP69142.1 - 4.2e-15 55.5 0.3 8e-15 54.6 0.3 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 EJP69142.1 - 2.3e-14 53.9 0.0 6.1e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.16 EJP69142.1 - 0.00054 20.2 5.3 0.00099 19.4 5.3 1.4 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 EJP69142.1 - 0.0033 17.3 6.2 0.0071 16.2 6.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 EJP69142.1 - 0.026 14.4 5.5 0.063 13.2 5.5 1.7 1 0 0 1 1 1 0 PHD-finger SPA PF08616.10 EJP69142.1 - 0.047 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Zf_RING PF16744.5 EJP69142.1 - 0.073 13.2 2.2 0.16 12.1 2.2 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger DUF974 PF06159.13 EJP69143.1 - 2.1e-82 276.6 0.0 2.6e-82 276.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) CcmH PF03918.14 EJP69143.1 - 0.16 11.3 0.1 0.45 9.8 0.1 1.8 1 0 0 1 1 1 0 Cytochrome C biogenesis protein KH_1 PF00013.29 EJP69144.1 - 3.2e-09 36.5 0.0 8.6e-08 31.9 0.0 2.4 2 0 0 2 2 2 1 KH domain DUF2277 PF10041.9 EJP69144.1 - 1.2 9.5 3.9 0.35 11.2 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) ALS_ss_C PF10369.9 EJP69145.1 - 4.3e-14 52.5 0.0 3.6e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EJP69145.1 - 2.2e-13 49.7 0.1 3.9e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EJP69145.1 - 8.5e-08 31.9 0.0 2.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EJP69145.1 - 0.074 13.1 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 ACT domain OTCace PF00185.24 EJP69146.1 - 9.9e-44 149.2 0.0 1.5e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EJP69146.1 - 5.2e-42 143.4 0.0 9.2e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain COesterase PF00135.28 EJP69147.1 - 4.5e-75 253.5 0.0 6.5e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EJP69147.1 - 0.0013 18.7 0.2 0.12 12.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ntox22 PF15527.6 EJP69147.1 - 0.0069 16.4 0.3 0.018 15.1 0.3 1.7 1 0 0 1 1 1 1 Bacterial toxin 22 Drf_FH1 PF06346.12 EJP69147.1 - 0.4 10.4 9.7 0.75 9.5 9.7 1.4 1 0 0 1 1 1 0 Formin Homology Region 1 HET PF06985.11 EJP69149.1 - 1e-08 35.7 6.2 9.6e-06 26.0 1.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PS_Dcarbxylase PF02666.15 EJP69150.1 - 1.5e-51 174.8 0.1 1.9e-51 174.4 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 EJP69150.1 - 0.016 15.1 0.1 1 9.4 0.1 2.6 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Gp5_C PF06715.12 EJP69150.1 - 0.037 14.1 0.2 0.037 14.1 0.2 2.1 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) Biotin_lipoyl_2 PF13533.6 EJP69150.1 - 0.1 12.4 0.9 0.3 11.0 0.5 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like Peptidase_M23 PF01551.22 EJP69150.1 - 0.16 12.2 0.1 0.89 9.8 0.1 2.1 2 0 0 2 2 2 0 Peptidase family M23 Pkinase PF00069.25 EJP69151.1 - 1.7e-25 89.9 0.0 9.9e-24 84.1 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69151.1 - 5.2e-07 29.2 0.0 0.087 12.1 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EJP69151.1 - 0.0092 15.9 0.1 0.031 14.2 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EJP69151.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJP69151.1 - 0.17 11.1 0.0 3.9 6.7 0.0 2.5 3 0 0 3 3 3 0 Kinase-like SHOCT PF09851.9 EJP69152.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Short C-terminal domain APH PF01636.23 EJP69153.1 - 5.2e-15 56.0 0.0 7.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP69153.1 - 0.00013 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase SE PF08491.10 EJP69153.1 - 0.055 12.5 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase RMI1_N PF08585.12 EJP69153.1 - 0.063 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein Pkinase PF00069.25 EJP69153.1 - 0.23 10.8 0.0 21 4.4 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Gly_transf_sug PF04488.15 EJP69154.1 - 1.4e-18 67.3 0.0 2.6e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3712 PF12505.8 EJP69155.1 - 6.7e-11 42.5 0.1 1.2e-07 32.1 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EJP69155.1 - 0.0011 19.5 0.2 27 5.4 0.1 3.9 3 0 0 3 3 3 3 Late embryogenesis abundant protein HATPase_c PF02518.26 EJP69156.1 - 3.7e-26 91.8 0.0 5.3e-25 88.1 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EJP69156.1 - 1.8e-25 89.3 0.0 3.3e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EJP69156.1 - 9.1e-13 48.1 0.0 2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EJP69156.1 - 0.00079 19.8 0.1 0.48 10.8 0.0 2.9 2 0 0 2 2 2 2 HAMP domain EzrA PF06160.12 EJP69156.1 - 0.085 11.0 3.1 0.044 12.0 0.2 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA YrhK PF14145.6 EJP69157.1 - 4 7.4 19.7 3.4 7.6 0.0 4.7 4 1 0 4 4 4 0 YrhK-like protein CDK2AP PF09806.9 EJP69158.1 - 0.039 14.0 2.2 0.068 13.2 1.5 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SUIM_assoc PF16619.5 EJP69158.1 - 6.1 7.0 13.1 0.98 9.5 4.6 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SART-1 PF03343.13 EJP69159.1 - 3.6e-176 587.4 51.9 4.3e-176 587.2 51.9 1.1 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.21 EJP69160.1 - 2.8e-99 332.9 0.0 4e-99 332.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EJP69160.1 - 1.9e-29 101.4 0.5 4e-29 100.4 0.5 1.6 1 0 0 1 1 1 1 Starch binding domain Cyclin PF08613.11 EJP69161.1 - 1.5e-30 106.7 3.7 1.9e-29 103.1 3.7 2.7 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EJP69161.1 - 0.0057 16.4 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Epimerase PF01370.21 EJP69162.1 - 5.4e-20 71.9 0.0 7e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP69162.1 - 8.7e-14 51.6 0.0 4.6e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EJP69162.1 - 8e-07 28.4 0.0 2.5e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EJP69162.1 - 1.1e-05 24.7 0.0 0.071 12.3 0.1 2.3 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EJP69162.1 - 0.00014 21.0 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EJP69162.1 - 0.00094 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EJP69162.1 - 0.0026 17.3 0.0 0.0049 16.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.23 EJP69162.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_17 PF00332.18 EJP69163.1 - 0.27 10.8 0.1 0.35 10.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Aa_trans PF01490.18 EJP69164.1 - 4.7e-39 134.2 21.1 6.5e-39 133.8 21.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans PF04082.18 EJP69165.1 - 7.5e-15 54.7 0.4 1.1e-14 54.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69166.1 - 3.6e-09 36.6 8.5 3.6e-09 36.6 8.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 EJP69168.1 - 2.8e-14 52.5 0.0 9.5e-14 50.7 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 EJP69168.1 - 2.7e-12 46.9 1.7 4.5e-11 43.0 0.2 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EJP69168.1 - 5.7e-11 42.2 0.0 8.4e-07 28.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP69168.1 - 2.4e-10 40.1 0.0 9e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP69168.1 - 2.8e-08 33.3 1.0 1.2e-05 24.6 0.1 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EJP69168.1 - 2.6e-07 30.6 0.0 0.001 18.7 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJP69168.1 - 3.3e-07 30.4 0.0 1.4e-06 28.4 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EJP69168.1 - 4.9e-05 22.8 0.0 0.2 10.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EJP69168.1 - 0.0047 15.7 0.0 0.13 11.0 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EJP69168.1 - 0.014 14.7 0.1 0.14 11.4 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EJP69168.1 - 0.029 13.4 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EJP69168.1 - 0.031 14.8 0.1 89 3.8 0.0 3.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP69168.1 - 0.034 13.4 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_10 PF13460.6 EJP69169.1 - 1.1e-20 74.4 0.2 1.7e-20 73.7 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EJP69169.1 - 3.5e-06 26.7 0.0 5.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EJP69169.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EJP69169.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 7tm_2 PF00002.24 EJP69170.1 - 5.9e-07 29.0 1.8 8.9e-07 28.4 1.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Peptidase_S10 PF00450.22 EJP69171.1 - 4.4e-80 270.1 0.0 6.1e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase C2 PF00168.30 EJP69173.1 - 5.1e-13 49.2 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain SUIM_assoc PF16619.5 EJP69173.1 - 0.0053 16.8 5.1 0.019 15.0 1.5 3.0 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 FKBP_C PF00254.28 EJP69175.1 - 5.2e-27 94.0 0.0 6e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N_2 PF18023.1 EJP69175.1 - 0.027 14.6 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 BDBT FKBP like N-terminal ThiF PF00899.21 EJP69176.1 - 2.7e-111 370.8 0.0 2.6e-76 256.2 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EJP69176.1 - 6.9e-91 304.6 1.7 1.1e-90 304.0 1.7 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EJP69176.1 - 1.7e-31 108.2 0.1 3.5e-31 107.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EJP69176.1 - 8.1e-26 90.0 1.6 1.1e-25 89.7 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 EJP69176.1 - 1.9e-21 76.5 0.1 3.8e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain Shikimate_DH PF01488.20 EJP69176.1 - 0.1 12.7 0.1 0.88 9.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GST_N_2 PF13409.6 EJP69177.1 - 6.5e-22 77.6 0.0 1.7e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP69177.1 - 3.3e-15 55.9 0.0 7.7e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EJP69177.1 - 0.00011 22.5 0.0 0.39 11.2 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EJP69177.1 - 0.00016 21.8 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP69177.1 - 0.00059 20.0 0.2 0.0025 18.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EJP69177.1 - 0.042 14.4 0.0 0.1 13.2 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3618 PF12277.8 EJP69178.1 - 0.034 14.4 3.5 0.034 14.4 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Phage_TAC_10 PF10963.8 EJP69178.1 - 0.085 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone Sulfatase PF00884.23 EJP69179.1 - 6.4e-16 58.6 1.2 1.6e-15 57.3 0.1 2.1 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 EJP69179.1 - 1.4e-06 28.2 0.1 2.6e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EJP69179.1 - 0.00033 20.1 0.1 0.00057 19.3 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily MFS_1 PF07690.16 EJP69180.1 - 2.4e-28 99.1 55.5 2.2e-17 63.0 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_10 PF13673.7 EJP69181.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP69181.1 - 0.0012 19.0 0.0 0.0019 18.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP69181.1 - 0.0039 17.6 0.0 0.0076 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EJP69183.1 - 4e-47 160.8 0.0 5.4e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69183.1 - 8.6e-27 94.0 0.0 1.4e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJP69183.1 - 0.0013 17.6 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EJP69183.1 - 0.0023 17.3 0.0 0.0085 15.4 0.1 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EJP69183.1 - 0.005 16.2 0.1 0.013 14.8 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.26 EJP69183.1 - 0.0051 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Sec1 PF00995.23 EJP69184.1 - 2.3e-116 390.4 0.0 2.6e-116 390.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Rx_N PF18052.1 EJP69184.1 - 0.37 11.1 1.4 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Rx N-terminal domain G-patch PF01585.23 EJP69185.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 G-patch domain Exo5 PF09810.9 EJP69186.1 - 2.4e-133 445.2 0.0 3e-133 444.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EJP69186.1 - 0.00045 20.2 1.0 0.8 9.6 0.0 3.8 3 1 0 3 3 3 2 PD-(D/E)XK nuclease superfamily F-box PF00646.33 EJP69187.1 - 1.6e-05 24.6 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EJP69187.1 - 0.0002 21.2 0.2 0.0003 20.6 0.2 1.3 1 0 0 1 1 1 1 F-box-like DHO_dh PF01180.21 EJP69190.1 - 1.6e-64 217.9 0.4 1.5e-55 188.5 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EJP69190.1 - 0.0015 17.7 0.9 0.15 11.0 0.7 2.5 2 0 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.17 EJP69190.1 - 0.0057 16.2 1.1 2.8 7.4 0.2 2.5 2 0 0 2 2 2 2 PcrB family Dak2 PF02734.17 EJP69190.1 - 0.014 15.3 1.5 0.028 14.3 0.2 2.0 2 0 0 2 2 2 0 DAK2 domain Fungal_trans PF04082.18 EJP69191.1 - 1.7e-09 37.1 0.0 4.4e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain YlbD_coat PF14071.6 EJP69191.1 - 0.12 12.6 0.8 1.9 8.8 1.3 2.5 2 0 0 2 2 2 0 Putative coat protein Abhydrolase_6 PF12697.7 EJP69193.1 - 0.016 15.8 9.6 0.036 14.7 6.8 3.0 2 2 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP69193.1 - 0.049 12.9 0.1 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EJP69193.1 - 0.05 13.1 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF676 PF05057.14 EJP69193.1 - 0.076 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 EJP69193.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Glyco_hydro_18 PF00704.28 EJP69195.1 - 8.2e-52 176.9 1.2 1.9e-51 175.7 1.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EJP69195.1 - 2.1e-06 28.1 9.3 2.1e-06 28.1 9.3 4.1 5 0 0 5 5 5 1 Chitin recognition protein LysM PF01476.20 EJP69195.1 - 0.077 13.1 0.0 19 5.4 0.0 3.2 3 0 0 3 3 3 0 LysM domain Glyco_hydro_20 PF00728.22 EJP69198.1 - 4.2e-26 92.2 0.1 1.1e-22 81.0 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 EJP69198.1 - 1.1e-08 35.8 0.1 2.9e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 His_Phos_2 PF00328.22 EJP69199.1 - 8e-18 64.9 0.0 7.1e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 EJP69199.1 - 0.034 13.8 0.1 0.79 9.4 0.0 2.8 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 EJP69200.1 - 1.1e-37 127.7 0.0 1.3e-11 44.1 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJP69200.1 - 5.5e-16 58.2 0.0 0.0091 15.8 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 EJP69200.1 - 3.6e-09 36.2 4.9 3.6e-09 36.2 4.9 3.6 4 0 0 4 4 4 1 Putative RRM domain DUF4523 PF15023.6 EJP69200.1 - 9.5e-06 25.5 0.0 0.096 12.5 0.0 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 EJP69200.1 - 9.9e-06 25.6 0.0 0.098 12.8 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif RRM_Rrp7 PF17799.1 EJP69200.1 - 0.004 17.0 0.1 0.66 9.8 0.0 3.9 3 1 2 5 5 5 1 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 EJP69200.1 - 0.019 15.0 0.0 0.43 10.7 0.1 2.7 3 0 0 3 3 3 0 RNA binding motif Nup35_RRM_2 PF14605.6 EJP69200.1 - 0.12 12.4 0.0 39 4.3 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 EJP69200.1 - 0.24 11.5 0.3 1.2 9.2 0.0 2.3 3 0 0 3 3 3 0 RNA binding domain Colipase PF01114.18 EJP69201.1 - 1.3 8.8 5.9 1.9 8.3 0.0 2.6 3 0 0 3 3 3 0 Colipase, N-terminal domain Popeye PF04831.13 EJP69201.1 - 4.1 7.6 8.9 1.5 9.0 5.7 1.7 2 0 0 2 2 2 0 Popeye protein conserved region Cullin PF00888.22 EJP69203.1 - 3.9e-169 564.2 0.0 4.7e-169 563.9 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EJP69203.1 - 1.5e-24 85.8 0.1 4e-24 84.4 0.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Asp PF00026.23 EJP69204.1 - 1.1e-24 87.5 0.0 6.4e-18 65.2 0.9 2.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Yae1_N PF09811.9 EJP69204.1 - 0.026 14.2 9.8 0.1 12.3 0.5 3.6 3 0 0 3 3 3 0 Essential protein Yae1, N terminal SKICH PF17751.1 EJP69205.1 - 0.046 14.3 0.3 0.059 13.9 0.3 1.2 1 0 0 1 1 1 0 SKICH domain PI3_PI4_kinase PF00454.27 EJP69206.1 - 1.8e-50 172.1 0.0 3.8e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EJP69206.1 - 2.6e-38 131.5 1.8 1.9e-37 128.7 0.0 3.0 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EJP69206.1 - 1.3e-11 44.1 0.0 4.2e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EJP69206.1 - 2.8e-07 30.1 3.4 6.8e-07 28.8 3.4 1.6 1 0 0 1 1 1 1 FAT domain FliS PF02561.14 EJP69206.1 - 0.067 13.5 0.0 0.36 11.1 0.0 2.3 1 0 0 1 1 1 0 Flagellar protein FliS Nup192 PF11894.8 EJP69207.1 - 0 1557.9 0.0 0 1557.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nefa_Nip30_N PF10187.9 EJP69207.1 - 0.37 11.2 1.7 1 9.8 1.7 1.7 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 zf-C3HC4_3 PF13920.6 EJP69208.1 - 1.4e-08 34.5 5.2 2.1e-08 33.9 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJP69208.1 - 3.2e-08 33.3 7.7 5.7e-08 32.5 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP69208.1 - 3.2e-07 30.6 6.2 5.5e-07 29.8 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EJP69208.1 - 6.2e-07 29.2 5.8 1.1e-06 28.4 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJP69208.1 - 1.2e-06 28.2 5.4 2.3e-06 27.4 5.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EJP69208.1 - 1.5e-05 24.8 6.6 2.6e-05 24.1 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EJP69208.1 - 1.7e-05 24.8 1.8 2.1e-05 24.5 0.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EJP69208.1 - 0.00019 21.4 2.1 0.00036 20.5 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EJP69208.1 - 0.00073 19.3 4.1 0.0014 18.4 4.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EJP69208.1 - 0.0013 19.0 2.7 0.0028 17.9 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EJP69208.1 - 0.0053 16.9 6.6 0.0089 16.2 6.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EJP69208.1 - 0.013 15.2 2.6 0.15 11.8 3.3 2.2 1 1 1 2 2 2 0 RING-like zinc finger Rad50_zn_hook PF04423.14 EJP69208.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-P11 PF03854.14 EJP69208.1 - 0.98 9.1 5.3 0.94 9.2 3.8 1.7 2 0 0 2 2 2 0 P-11 zinc finger TFIIA PF03153.13 EJP69208.1 - 5.1 7.0 6.5 6.6 6.6 6.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FANCL_C PF11793.8 EJP69208.1 - 6.7 7.0 6.3 61 3.9 6.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DNApol_Exo PF18136.1 EJP69209.1 - 4.5e-107 357.4 0.0 8.3e-107 356.5 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EJP69209.1 - 1.3e-54 185.7 0.0 2.2e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EJP69209.1 - 0.36 10.5 2.7 3.4 7.3 0.8 2.9 2 1 0 2 2 2 0 3'-5' exonuclease Kinetochor_Ybp2 PF08568.10 EJP69210.1 - 9.4e-91 305.2 0.0 1.1e-90 305.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Xlink PF00193.17 EJP69210.1 - 0.053 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Extracellular link domain G-patch_2 PF12656.7 EJP69211.1 - 8.1e-19 67.5 0.2 8.1e-19 67.5 0.2 2.8 3 1 0 3 3 3 1 G-patch domain DUF4598 PF15370.6 EJP69211.1 - 0.17 12.4 0.2 0.17 12.4 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4598) Myb_DNA-bind_6 PF13921.6 EJP69212.1 - 2.4e-16 59.7 0.2 7.4e-16 58.1 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 EJP69212.1 - 5.8e-13 49.0 0.2 5.8e-13 49.0 0.2 3.4 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 EJP69212.1 - 5e-05 23.4 0.2 0.00012 22.2 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Na_H_Exchanger PF00999.21 EJP69213.1 - 1e-75 254.9 41.4 1.3e-75 254.6 41.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Arf PF00025.21 EJP69214.1 - 1.3e-41 141.9 0.0 2e-41 141.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EJP69214.1 - 5.3e-15 55.4 0.0 1.3e-09 37.7 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EJP69214.1 - 3e-09 37.1 0.0 6e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJP69214.1 - 1.2e-08 34.8 0.0 5.6e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EJP69214.1 - 5.2e-08 32.5 0.0 6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EJP69214.1 - 4e-07 29.6 0.0 1.5e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EJP69214.1 - 0.00037 20.6 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJP69214.1 - 0.00038 20.1 0.5 0.0028 17.2 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RNase_PH PF01138.21 EJP69215.1 - 1.5e-23 83.7 0.0 2.3e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EJP69215.1 - 2.8e-08 33.7 0.0 5.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 EJP69216.1 - 3.8e-83 279.0 17.2 4.4e-83 278.8 17.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BNIP2 PF12496.8 EJP69216.1 - 0.16 12.4 9.7 0.048 14.1 7.0 1.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Nop14 PF04147.12 EJP69216.1 - 2.1 6.4 20.8 2.4 6.3 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF5401 PF17380.2 EJP69216.1 - 2.9 5.9 15.8 3.9 5.4 15.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SAPS PF04499.15 EJP69216.1 - 3 6.5 7.8 3.6 6.3 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 EJP69216.1 - 4 5.6 18.8 4.8 5.4 18.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FGGY_C PF02782.16 EJP69217.1 - 2.2e-23 83.0 0.0 4.3e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EJP69217.1 - 3.3e-13 49.8 0.0 7.5e-13 48.6 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.21 EJP69218.1 - 3e-51 174.0 4.7 4.1e-51 173.5 4.7 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EJP69218.1 - 0.021 14.9 0.9 0.054 13.6 0.1 2.2 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter SIR2 PF02146.17 EJP69219.1 - 5.9e-33 114.3 0.0 1.1e-32 113.4 0.0 1.4 1 1 0 1 1 1 1 Sir2 family DUF5321 PF17254.2 EJP69220.1 - 1.9e-58 196.4 1.6 2.7e-58 195.9 1.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Peptidase_C50 PF03568.17 EJP69221.1 - 1.3e-163 544.8 0.0 2.5e-162 540.5 0.0 2.3 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 EJP69221.1 - 2.9e-06 27.5 18.9 0.46 10.8 0.3 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP69221.1 - 8.2e-05 23.1 8.1 25 6.0 0.0 8.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 EJP69221.1 - 0.0038 17.2 4.1 5 7.4 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat CHAT PF12770.7 EJP69221.1 - 0.0053 16.2 3.4 0.074 12.4 0.0 4.0 3 1 0 3 3 3 1 CHAT domain TPR_1 PF00515.28 EJP69221.1 - 0.066 13.1 7.8 13 5.8 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EJP69221.1 - 0.11 12.7 20.7 0.78 10.0 0.1 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 EJP69221.1 - 0.23 12.1 5.8 20 6.0 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat SPO22 PF08631.10 EJP69221.1 - 0.27 10.7 7.4 0.53 9.7 0.4 3.8 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_10 PF13374.6 EJP69221.1 - 0.4 10.6 3.9 1.9e+02 2.1 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Antimicrobial_3 PF08025.11 EJP69221.1 - 0.67 9.9 2.2 3 7.8 0.1 3.1 4 0 0 4 4 4 0 Spider antimicrobial peptide TPR_8 PF13181.6 EJP69221.1 - 0.84 10.0 9.7 39 4.8 0.2 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat FAA_hydro_N_2 PF18288.1 EJP69221.1 - 0.86 10.1 3.2 2.2 8.7 0.1 3.4 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 DUF3439 PF11921.8 EJP69222.1 - 0.61 10.1 7.0 0.82 9.7 5.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Fungal_trans PF04082.18 EJP69223.1 - 2.1e-29 102.4 0.0 3.9e-29 101.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69223.1 - 1.4e-09 37.9 11.1 2.5e-09 37.1 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kri1 PF05178.12 EJP69224.1 - 1.1e-31 109.4 12.3 1.1e-31 109.4 12.3 5.8 6 2 1 7 7 7 1 KRI1-like family Kri1_C PF12936.7 EJP69224.1 - 6.8e-27 93.5 0.1 6.8e-27 93.5 0.1 4.4 3 1 1 4 4 4 1 KRI1-like family C-terminal Ras PF00071.22 EJP69225.1 - 5.6e-58 195.1 0.0 6.6e-58 194.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP69225.1 - 2.5e-34 118.1 0.0 3.6e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP69225.1 - 2.5e-13 49.8 0.0 3.5e-13 49.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EJP69225.1 - 1.8e-05 24.4 0.0 2.8e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EJP69225.1 - 2.2e-05 24.0 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJP69225.1 - 4.4e-05 23.5 0.0 7.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EJP69225.1 - 0.0009 19.7 0.0 0.0014 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EJP69225.1 - 0.048 13.6 0.3 1.9 8.4 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase zf-C3HC4_3 PF13920.6 EJP69226.1 - 0.0053 16.6 12.6 0.0084 16.0 12.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EJP69226.1 - 0.021 14.7 6.9 0.035 14.0 6.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 EJP69226.1 - 0.028 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain PI3_PI4_kinase PF00454.27 EJP69227.1 - 5e-33 115.0 0.0 1.3e-32 113.6 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 EJP69227.1 - 2.5e-20 72.2 0.1 5.2e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 EJP69227.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CXCR4_N PF12109.8 EJP69227.1 - 0.097 12.9 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal DUF3455 PF11937.8 EJP69227.1 - 0.14 12.6 0.6 0.53 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3455) PI3Ka PF00613.20 EJP69227.1 - 0.23 10.9 0.5 0.47 9.8 0.5 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CBFD_NFYB_HMF PF00808.23 EJP69228.1 - 2.5e-13 50.1 1.3 3.7e-13 49.5 1.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EJP69228.1 - 0.014 15.7 0.2 0.014 15.7 0.2 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EJP69228.1 - 0.17 12.0 1.0 0.3 11.2 1.0 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Abhydrolase_3 PF07859.13 EJP69229.1 - 1.5e-22 80.6 0.0 2.5e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EJP69229.1 - 1.5e-21 76.7 0.0 2.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF3605 PF12239.8 EJP69230.1 - 6.3e-55 185.7 0.0 7.6e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) TMEM208_SND2 PF05620.11 EJP69231.1 - 6.2e-50 169.3 0.1 6.8e-50 169.1 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF1467 PF07330.12 EJP69231.1 - 0.033 14.1 2.1 0.035 14.0 0.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1467) TPR_1 PF00515.28 EJP69232.1 - 1.7e-37 125.7 20.7 4.8e-08 32.5 0.0 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 EJP69232.1 - 1.4e-34 115.4 26.5 3.3e-06 26.8 0.0 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP69232.1 - 4.9e-31 106.8 16.6 8.5e-23 80.4 0.1 5.2 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EJP69232.1 - 1.5e-25 87.2 13.9 0.00043 20.3 0.0 10.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EJP69232.1 - 5.3e-21 73.5 24.2 0.0055 17.4 0.0 10.7 5 2 6 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EJP69232.1 - 1.5e-20 73.5 25.0 1.7e-09 38.1 0.3 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 EJP69232.1 - 3.2e-19 69.0 18.3 0.0012 19.0 0.9 8.5 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EJP69232.1 - 5e-19 68.6 17.2 0.00018 21.9 0.2 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 EJP69232.1 - 2.9e-17 61.3 9.9 0.029 14.4 0.0 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJP69232.1 - 3.1e-17 61.6 12.1 0.085 13.3 0.1 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EJP69232.1 - 1.4e-16 59.9 15.8 9.2e-06 25.3 1.1 8.0 6 1 3 9 9 8 4 TPR repeat TPR_6 PF13174.6 EJP69232.1 - 1.1e-11 44.5 15.7 0.018 15.6 0.0 9.9 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_15 PF13429.6 EJP69232.1 - 5.8e-07 29.0 14.0 0.0025 17.1 5.6 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJP69232.1 - 5e-05 23.4 18.9 0.089 13.0 0.1 6.6 5 2 2 7 7 7 2 Tetratricopeptide repeat DUF2225 PF09986.9 EJP69232.1 - 0.0063 16.3 1.4 0.23 11.1 0.8 3.0 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) PknG_TPR PF16918.5 EJP69232.1 - 0.019 13.7 6.0 0.12 11.1 0.6 3.0 2 1 1 3 3 3 0 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 EJP69232.1 - 0.066 13.6 4.9 0.65 10.4 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Muraidase PF11860.8 EJP69232.1 - 0.067 13.4 1.0 1.4 9.1 0.0 2.7 1 1 2 3 3 3 0 N-acetylmuramidase DUF5113 PF17140.4 EJP69232.1 - 0.2 11.5 0.7 0.61 9.9 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) Sel1 PF08238.12 EJP69232.1 - 0.27 12.0 3.0 5.5 7.8 0.1 4.3 5 0 0 5 5 4 0 Sel1 repeat MIT PF04212.18 EJP69232.1 - 0.47 10.6 5.6 54 4.0 0.4 5.0 3 2 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 EJP69232.1 - 6.9 7.6 10.3 1.9e+02 3.1 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EJP69232.1 - 7.7 6.5 15.2 23 5.0 0.1 6.3 6 1 1 7 7 6 0 Tetratricopeptide repeat CENP-T_C PF15511.6 EJP69233.1 - 2.9e-09 37.0 0.1 3.5e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EJP69233.1 - 9.2e-06 26.0 0.2 1.1e-05 25.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EJP69233.1 - 3.3e-05 24.0 0.1 4.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EJP69233.1 - 5.7e-05 23.3 0.1 9.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EJP69233.1 - 0.00028 21.2 0.1 0.00048 20.4 0.1 1.5 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EJP69233.1 - 0.0033 17.5 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit HIGH_NTase1_ass PF16581.5 EJP69233.1 - 0.028 14.4 0.0 0.032 14.2 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Bromo_TP PF07524.13 EJP69233.1 - 0.04 13.9 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Ribosomal_S17e PF00833.18 EJP69233.1 - 0.1 12.5 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal S17 Sedlin_N PF04628.13 EJP69234.1 - 2.5e-43 147.4 0.0 3e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EJP69234.1 - 0.00013 21.9 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 2 Sybindin-like family Corona_6B_7B PF03262.13 EJP69234.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein DUF4110 PF13422.6 EJP69234.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) L31 PF09784.9 EJP69235.1 - 1.4e-45 153.9 0.9 1.5e-45 153.8 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 RRM_1 PF00076.22 EJP69236.1 - 1.2e-15 57.0 0.0 1.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sipho_Gp157 PF05565.11 EJP69237.1 - 0.29 11.1 3.1 0.37 10.8 1.4 1.9 2 0 0 2 2 2 0 Siphovirus Gp157 EBP PF05241.12 EJP69238.1 - 7e-46 155.9 11.2 9.8e-46 155.4 11.2 1.2 1 0 0 1 1 1 1 Emopamil binding protein p450 PF00067.22 EJP69240.1 - 7.4e-58 196.4 0.0 9.8e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.6 EJP69241.1 - 1.9e-29 101.7 21.1 6.8e-09 35.9 1.0 7.7 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 EJP69241.1 - 1.3e-16 59.8 15.9 0.00031 20.5 0.1 8.8 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.14 EJP69241.1 - 2.9e-08 33.5 2.3 0.0021 18.5 0.6 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP69241.1 - 1.2e-06 28.1 8.6 1.2 9.3 0.0 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 EJP69241.1 - 1.3e-06 27.8 0.0 5e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.6 EJP69241.1 - 3.5e-06 27.6 3.0 0.00011 22.8 0.2 4.0 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP69241.1 - 4e-06 27.2 7.8 1.6 9.3 0.0 5.2 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP69241.1 - 6.2e-06 25.8 4.9 6.2e-06 25.8 4.9 2.7 2 1 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 EJP69241.1 - 4.1e-05 23.5 8.9 4.3 7.8 0.0 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EJP69241.1 - 5e-05 23.1 10.5 0.18 12.0 0.1 5.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJP69241.1 - 5.9e-05 23.6 5.8 0.3 12.0 0.1 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP69241.1 - 0.00041 20.0 9.1 1.8 8.6 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EJP69241.1 - 0.00051 20.5 0.8 0.49 11.2 0.0 3.8 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 EJP69241.1 - 0.00089 19.7 2.3 0.014 15.8 0.0 3.5 2 1 1 3 3 3 1 AAA ATPase domain NACHT PF05729.12 EJP69241.1 - 0.0081 16.1 0.2 0.33 10.9 0.0 3.7 4 1 0 4 4 4 1 NACHT domain Helo_like_N PF17111.5 EJP69241.1 - 0.014 14.8 0.8 0.15 11.4 0.8 2.3 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins HGD-D PF06050.13 EJP69241.1 - 0.036 13.8 0.3 0.29 10.8 0.0 2.6 3 1 0 3 3 3 0 2-hydroxyglutaryl-CoA dehydratase, D-component AAA_18 PF13238.6 EJP69241.1 - 0.11 13.1 0.0 1.3 9.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EJP69241.1 - 0.2 11.7 0.0 0.56 10.3 0.0 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ANAPC3 PF12895.7 EJP69241.1 - 0.72 10.1 7.6 12 6.2 0.0 4.6 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EJP69241.1 - 1.7 9.0 3.9 55 4.3 0.0 4.3 5 0 0 5 5 5 0 PPR repeat 5_nucleotid_C PF02872.18 EJP69242.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain PrpF PF04303.13 EJP69243.1 - 6.1e-80 268.9 0.0 7.1e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 PrpF protein GGACT PF06094.12 EJP69244.1 - 2.4e-07 31.4 0.0 3.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EJP69244.1 - 1.1e-06 29.0 0.0 4.7e-06 26.9 0.0 2.0 2 1 0 2 2 2 1 AIG2-like family Pkinase PF00069.25 EJP69245.1 - 2.6e-68 230.2 0.0 5.4e-68 229.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69245.1 - 2.9e-49 167.7 0.0 4.9e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EJP69245.1 - 4.3e-27 94.4 0.0 8.5e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 EJP69245.1 - 7.4e-16 58.0 0.1 1.6e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EJP69245.1 - 6.2e-15 55.4 0.1 1.2e-14 54.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EJP69245.1 - 1e-12 48.5 0.1 1.8e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 EJP69245.1 - 1.1e-06 28.2 0.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.16 EJP69245.1 - 0.0076 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_4 PF18017.1 EJP69245.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 EJP69245.1 - 0.024 13.4 0.0 0.066 12.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase SAM_Ste50p PF09235.10 EJP69245.1 - 0.075 13.3 1.3 0.19 12.0 1.3 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Sulfotransfer_3 PF13469.6 EJP69246.1 - 0.00011 22.6 0.0 0.00062 20.2 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase family Mhr1 PF12829.7 EJP69247.1 - 9.4e-32 109.0 0.0 1.6e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination AAA_2 PF07724.14 EJP69248.1 - 4e-46 157.3 0.0 2.3e-44 151.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EJP69248.1 - 1.2e-31 108.6 4.2 1.2e-31 108.6 4.2 4.2 4 0 0 4 4 3 1 AAA lid domain AAA PF00004.29 EJP69248.1 - 3e-26 92.4 0.7 5.4e-14 52.7 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EJP69248.1 - 1.2e-23 83.0 2.5 2e-23 82.2 0.8 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EJP69248.1 - 1.1e-14 54.6 0.2 3.6e-09 36.7 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EJP69248.1 - 1e-12 48.8 9.3 2.3e-06 28.1 0.1 5.2 4 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 EJP69248.1 - 1e-11 45.3 0.0 0.00035 20.8 0.0 4.0 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EJP69248.1 - 8.8e-09 35.3 0.0 2.1e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 EJP69248.1 - 1.2e-06 28.5 5.9 2.4e-05 24.3 0.1 4.5 4 0 0 4 4 4 1 Clp amino terminal domain, pathogenicity island component AAA_7 PF12775.7 EJP69248.1 - 1.6e-06 27.8 0.0 0.0063 16.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EJP69248.1 - 2.6e-06 28.0 1.5 0.14 12.7 0.0 4.2 4 1 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 EJP69248.1 - 7.5e-06 25.8 0.0 0.056 13.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EJP69248.1 - 7.5e-06 26.0 0.0 0.093 12.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EJP69248.1 - 8.8e-06 25.9 0.1 0.26 11.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 EJP69248.1 - 3.6e-05 24.1 0.2 0.37 11.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 EJP69248.1 - 4.2e-05 23.0 0.1 0.12 11.8 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EJP69248.1 - 5.3e-05 23.0 0.0 0.07 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EJP69248.1 - 6.5e-05 23.0 5.1 0.071 13.0 0.3 4.5 4 1 0 4 4 4 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EJP69248.1 - 7.8e-05 23.0 0.0 0.45 10.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 EJP69248.1 - 0.00011 22.2 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EJP69248.1 - 0.00018 21.3 0.1 7 6.4 0.0 4.2 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EJP69248.1 - 0.00031 20.7 0.1 0.37 10.7 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase AAA_19 PF13245.6 EJP69248.1 - 0.00037 20.8 1.2 0.31 11.4 0.1 4.1 5 1 0 5 5 3 1 AAA domain T2SSE PF00437.20 EJP69248.1 - 0.00049 19.2 1.3 0.0053 15.9 0.5 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.11 EJP69248.1 - 0.00084 19.2 0.0 4 7.3 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EJP69248.1 - 0.0011 19.0 0.0 0.0041 17.2 0.0 1.9 2 0 0 2 2 1 1 Torsin AAA_30 PF13604.6 EJP69248.1 - 0.0012 18.6 0.0 2.2 8.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EJP69248.1 - 0.0014 18.6 0.1 2.6 7.9 0.0 2.9 3 0 0 3 3 2 2 Rad17 P-loop domain ABC_tran PF00005.27 EJP69248.1 - 0.0033 18.0 3.2 0.76 10.3 0.0 3.5 3 1 0 3 3 2 1 ABC transporter Zeta_toxin PF06414.12 EJP69248.1 - 0.0037 16.6 0.0 0.55 9.5 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 EJP69248.1 - 0.0047 16.6 0.0 5.5 6.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.15 EJP69248.1 - 0.0048 16.9 0.0 0.57 10.2 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit NACHT PF05729.12 EJP69248.1 - 0.0049 16.8 0.0 0.61 10.0 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Roc PF08477.13 EJP69248.1 - 0.0094 16.2 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 EJP69248.1 - 0.015 15.3 0.2 55 3.8 0.0 3.7 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 EJP69248.1 - 0.024 14.5 0.0 0.78 9.6 0.0 2.9 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 EJP69248.1 - 0.047 13.2 2.3 3.4 7.2 0.0 3.4 3 1 1 4 4 3 0 AAA domain ATP_bind_1 PF03029.17 EJP69248.1 - 0.05 13.4 0.0 9.4 5.9 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein B2 PF11473.8 EJP69248.1 - 0.12 12.2 0.1 14 5.5 0.1 2.9 2 0 0 2 2 2 0 RNA binding protein B2 PduV-EutP PF10662.9 EJP69248.1 - 0.12 12.1 0.0 7.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 EJP69248.1 - 0.35 11.3 0.0 0.35 11.3 0.0 4.3 2 1 0 2 2 1 0 AAA domain V_ATPase_I PF01496.19 EJP69248.1 - 1.3 6.9 5.1 2.1 6.2 5.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sugarporin_N PF11471.8 EJP69248.1 - 4.9 7.2 8.5 13 5.8 0.2 2.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension CCDC53 PF10152.9 EJP69249.1 - 0.33 11.3 2.7 0.64 10.4 0.1 2.4 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex PIG-X PF08320.12 EJP69250.1 - 7.4e-66 222.1 0.0 1.2e-65 221.4 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Homeodomain PF00046.29 EJP69251.1 - 2.6e-06 27.2 2.6 1.7e-05 24.6 0.1 2.8 2 0 0 2 2 2 1 Homeodomain Rhodanese PF00581.20 EJP69251.1 - 0.057 13.9 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain Prefoldin_2 PF01920.20 EJP69251.1 - 0.25 11.3 1.3 0.47 10.4 1.3 1.4 1 0 0 1 1 1 0 Prefoldin subunit Homeobox_KN PF05920.11 EJP69253.1 - 3.6e-21 74.8 0.9 7.2e-21 73.8 0.9 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EJP69253.1 - 2.7e-08 33.5 2.9 3e-08 33.4 1.7 1.7 2 0 0 2 2 2 1 Homeodomain DNA_pol_E_B PF04042.16 EJP69253.1 - 0.061 12.7 0.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B Fungal_trans PF04082.18 EJP69254.1 - 2.2e-11 43.3 0.0 4.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69254.1 - 0.032 14.4 2.6 0.055 13.6 2.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 EJP69255.1 - 1.6e-73 247.9 0.4 2e-73 247.6 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP69255.1 - 2.2e-15 57.3 0.3 8.9e-13 48.9 0.2 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP69255.1 - 1.4e-07 32.0 0.1 0.1 13.2 0.0 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EJP69255.1 - 0.0041 16.9 0.0 0.2 11.4 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EJP69255.1 - 0.0084 16.6 0.0 5.1 7.7 0.0 3.8 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease ATP-synt_C PF00137.21 EJP69256.1 - 1.5e-26 92.5 26.3 6e-20 71.4 11.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SH PF01445.17 EJP69256.1 - 0.07 13.1 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Viral small hydrophobic protein DUF4577 PF15145.6 EJP69256.1 - 0.12 12.4 0.3 0.21 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF2975 PF11188.8 EJP69256.1 - 4.5 7.2 10.5 0.64 9.9 6.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) Pep3_Vps18 PF05131.14 EJP69257.1 - 4e-41 140.3 0.0 1.1e-40 138.9 0.0 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EJP69257.1 - 1.1e-08 35.0 6.8 6.6e-07 29.3 0.2 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EJP69257.1 - 0.00037 20.1 0.1 0.00073 19.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF2175 PF09943.9 EJP69257.1 - 0.00054 20.2 0.3 0.0031 17.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.6 EJP69257.1 - 0.00071 19.4 0.7 0.0016 18.2 0.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP69257.1 - 0.0031 17.4 0.3 0.0031 17.4 0.3 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Vps39_2 PF10367.9 EJP69257.1 - 0.0042 17.5 0.0 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 EJP69257.1 - 0.0094 16.3 0.5 0.024 14.9 0.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EJP69257.1 - 0.076 13.3 0.3 0.21 11.9 0.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EJP69257.1 - 0.21 11.6 0.5 0.64 10.1 0.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 EJP69257.1 - 0.48 10.5 6.2 0.097 12.7 1.9 2.1 2 0 0 2 2 2 0 Zinc-finger zf-RING_11 PF17123.5 EJP69257.1 - 0.61 9.9 10.6 0.048 13.4 4.5 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 EJP69257.1 - 1.6 8.6 3.7 0.48 10.3 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PDT PF00800.18 EJP69258.1 - 2.1e-57 193.9 0.0 2.6e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EJP69258.1 - 0.00035 20.3 0.0 0.00098 18.9 0.0 1.8 1 0 0 1 1 1 1 ACT domain MFS_1 PF07690.16 EJP69259.1 - 3.4e-25 88.7 30.2 3.4e-25 88.7 30.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP69259.1 - 7.9e-10 38.2 32.2 1.7e-08 33.8 32.2 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.18 EJP69259.1 - 0.22 11.5 0.4 0.36 10.8 0.4 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase DUF1992 PF09350.10 EJP69260.1 - 5.4e-20 71.3 0.3 2.1e-19 69.4 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DUF2383 PF09537.10 EJP69260.1 - 0.039 14.3 1.8 67 3.9 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF2383) DUF5356 PF17309.2 EJP69260.1 - 0.062 13.3 1.9 0.14 12.2 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5356) Sugar_tr PF00083.24 EJP69261.1 - 1.1e-81 275.1 19.2 1.2e-81 274.9 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP69261.1 - 1.8e-12 46.9 28.8 1.6e-09 37.1 9.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EJP69261.1 - 0.00097 18.1 4.2 0.00097 18.1 4.2 2.3 2 0 0 2 2 2 1 MFS_1 like family Aminotran_1_2 PF00155.21 EJP69262.1 - 7.4e-93 311.6 0.0 8.7e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ku_C PF03730.14 EJP69263.1 - 0.072 13.8 0.1 0.072 13.8 0.1 2.8 3 2 0 3 3 3 0 Ku70/Ku80 C-terminal arm Ribosomal_L28 PF00830.19 EJP69264.1 - 2.3e-11 43.7 0.5 3.9e-11 43.0 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Trp_syntA PF00290.20 EJP69265.1 - 1e-82 276.9 0.0 1.7e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EJP69265.1 - 3.5e-47 161.2 1.6 5.9e-47 160.5 1.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme STN PF07660.14 EJP69265.1 - 0.22 11.3 1.0 21 5.0 0.1 2.5 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain DUF3679 PF12438.8 EJP69266.1 - 0.15 11.8 7.3 4.1 7.2 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) MCPsignal PF00015.21 EJP69266.1 - 0.16 11.8 1.4 24 4.7 0.4 2.9 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.12 EJP69266.1 - 0.23 11.5 3.2 11 6.1 0.1 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EJP69266.1 - 0.58 10.4 12.2 0.37 11.1 0.3 4.9 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Abhydrolase_9_N PF15420.6 EJP69266.1 - 4.5 7.2 14.0 0.91 9.5 5.0 3.0 3 1 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Atg8 PF02991.16 EJP69267.1 - 2.4e-51 172.3 0.2 2.8e-51 172.0 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EJP69267.1 - 3.9e-06 27.2 0.0 4.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 EJP69268.1 - 1.7e-142 473.5 0.3 2e-142 473.2 0.3 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Amidohydro_3 PF07969.11 EJP69268.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family SWIM PF04434.17 EJP69269.1 - 0.015 14.9 4.0 0.55 10.0 0.1 2.6 2 0 0 2 2 2 0 SWIM zinc finger MitMem_reg PF13012.6 EJP69270.1 - 6.4e-38 129.6 0.3 1.3e-37 128.6 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EJP69270.1 - 1.1e-29 102.8 0.1 2.8e-29 101.5 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mak10 PF04112.13 EJP69270.1 - 0.061 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA_bind_2 PF13725.6 EJP69270.1 - 0.16 11.6 4.4 0.22 11.2 4.4 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain RP-C_C PF11800.8 EJP69270.1 - 0.45 10.6 3.7 0.77 9.8 3.7 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Connexin PF00029.19 EJP69270.1 - 0.72 9.6 1.9 1 9.1 1.9 1.2 1 0 0 1 1 1 0 Connexin GMC_oxred_N PF00732.19 EJP69271.1 - 9.8e-63 212.3 0.0 1.6e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP69271.1 - 2.5e-30 105.9 0.0 3.9e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EJP69271.1 - 0.00027 20.1 0.4 0.033 13.3 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EJP69271.1 - 0.00075 19.2 1.4 0.034 13.7 0.4 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HHH_5 PF14520.6 EJP69271.1 - 0.021 15.4 0.4 0.34 11.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Lycopene_cycl PF05834.12 EJP69271.1 - 0.021 13.9 0.2 0.034 13.2 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EJP69271.1 - 0.042 14.1 0.4 0.11 12.7 0.4 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EJP69271.1 - 0.11 11.6 0.2 0.18 10.8 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EJP69271.1 - 0.14 11.4 2.1 2.6 7.2 1.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADK PF00406.22 EJP69272.1 - 1.1e-57 194.4 0.0 1.4e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EJP69272.1 - 2.3e-23 83.1 0.3 5e-23 82.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EJP69272.1 - 2.3e-17 62.6 0.0 5.2e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EJP69272.1 - 2.3e-05 25.0 0.0 5e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EJP69272.1 - 0.00051 20.2 0.0 0.00098 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EJP69272.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 EJP69272.1 - 0.24 11.8 1.1 8.2 6.9 0.1 3.0 3 0 0 3 3 3 0 Csm1 N-terminal domain HOOK PF05622.12 EJP69273.1 - 5.9e-11 41.3 60.7 5.9e-11 41.3 60.7 2.3 1 1 1 2 2 2 2 HOOK protein Tk-SP_N-pro PF18237.1 EJP69274.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Tk-SP N-propeptide domain Transferase PF02458.15 EJP69275.1 - 3.8e-05 22.5 0.0 0.74 8.4 0.0 3.1 3 0 0 3 3 3 3 Transferase family adh_short_C2 PF13561.6 EJP69276.1 - 7.9e-56 189.2 0.2 9.8e-56 188.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP69276.1 - 2.3e-49 167.5 0.2 3e-49 167.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP69276.1 - 1.7e-10 41.1 0.5 5e-10 39.6 0.5 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP69276.1 - 4.1e-06 26.4 0.0 5.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EJP69276.1 - 0.035 13.2 0.4 0.091 11.8 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 EJP69276.1 - 0.058 13.4 0.5 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_transf_5 PF08323.11 EJP69276.1 - 0.086 12.5 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain NAD_binding_7 PF13241.6 EJP69276.1 - 0.095 13.1 0.1 0.29 11.6 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding ADH_N PF08240.12 EJP69277.1 - 1.5e-27 95.7 1.5 2.5e-27 94.9 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP69277.1 - 8.2e-17 61.4 1.6 1.5e-16 60.6 1.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EJP69277.1 - 3e-08 33.4 2.0 0.0027 17.2 0.2 2.5 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EJP69277.1 - 0.00017 21.0 2.6 0.00017 21.0 2.6 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EJP69277.1 - 0.00025 20.3 1.1 0.00036 19.7 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EJP69277.1 - 0.0064 16.9 0.8 0.015 15.7 0.8 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.6 EJP69277.1 - 0.0073 17.4 0.1 0.022 15.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase HI0933_like PF03486.14 EJP69277.1 - 0.014 14.1 1.7 0.021 13.6 1.7 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 EJP69277.1 - 0.025 14.1 4.5 0.071 12.7 0.4 3.1 2 1 2 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 EJP69277.1 - 0.04 14.0 0.6 0.078 13.0 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EJP69277.1 - 0.052 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EJP69277.1 - 0.069 13.4 0.8 0.38 11.0 0.6 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EJP69277.1 - 0.071 13.0 2.3 0.11 12.3 2.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EJP69277.1 - 0.41 9.7 3.3 0.6 9.1 3.1 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A Aldo_ket_red PF00248.21 EJP69278.1 - 1.3e-44 152.6 0.0 1.6e-42 145.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 EJP69279.1 - 2.3e-68 230.4 0.0 3.1e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69279.1 - 1.4e-31 109.7 0.0 1.9e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP69279.1 - 0.00071 19.0 0.2 0.0012 18.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EJP69279.1 - 0.00087 18.3 0.1 0.0014 17.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EJP69279.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EJP69279.1 - 0.025 14.5 0.2 0.046 13.6 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EJP69279.1 - 0.087 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.11 EJP69279.1 - 0.099 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.19 EJP69279.1 - 0.13 12.0 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.15 EJP69280.1 - 3.2e-72 243.0 0.0 6.2e-72 242.1 0.0 1.5 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EJP69280.1 - 1.1e-24 86.3 0.0 3.7e-24 84.5 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EJP69280.1 - 3.5e-18 66.1 0.1 7.4e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EJP69280.1 - 8.8e-17 60.9 5.6 1.6e-16 60.1 5.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EJP69280.1 - 4.4e-08 32.9 0.5 1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EJP69280.1 - 0.025 14.0 0.3 0.051 13.0 0.3 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cadherin_C_2 PF16492.5 EJP69281.1 - 0.12 13.2 0.0 0.14 12.9 0.0 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Sec23_trunk PF04811.15 EJP69282.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Zn_clus PF00172.18 EJP69282.1 - 1.4 9.1 10.6 0.096 12.8 5.3 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain IBN_N PF03810.19 EJP69283.1 - 1.5e-06 28.0 5.1 3.1e-06 27.0 0.1 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EJP69283.1 - 1e-05 25.7 0.4 0.002 18.2 0.0 3.8 4 0 0 4 4 4 1 Exportin 1-like protein MOR2-PAG1_N PF14222.6 EJP69283.1 - 0.029 13.3 0.1 0.46 9.4 0.0 2.4 2 0 0 2 2 2 0 Cell morphogenesis N-terminal IPPT PF01715.17 EJP69283.1 - 0.081 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 IPP transferase DUF1917 PF08939.10 EJP69285.1 - 7e-72 242.5 0.0 8.5e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Acetyltransf_1 PF00583.25 EJP69286.1 - 5.9e-19 68.4 0.0 8e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP69286.1 - 8.1e-11 42.0 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP69286.1 - 9e-09 35.7 0.0 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP69286.1 - 2.4e-08 33.8 0.0 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EJP69286.1 - 2.1e-06 27.8 0.0 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EJP69286.1 - 1.2e-05 26.0 0.0 1.5e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EJP69286.1 - 7.8e-05 22.4 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EJP69286.1 - 0.0022 18.1 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 EJP69286.1 - 0.064 13.1 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LCAT PF02450.15 EJP69287.1 - 1.5e-103 347.0 0.0 1.9e-103 346.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EJP69287.1 - 0.087 13.4 0.7 0.33 11.5 0.3 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2013 PF09431.10 EJP69288.1 - 5.5e-52 175.6 0.4 1.3e-51 174.4 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) PH PF00169.29 EJP69289.1 - 2.1e-05 25.0 0.0 5.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.11 EJP69289.1 - 0.0073 14.3 0.7 0.01 13.8 0.7 1.1 1 0 0 1 1 1 1 Prominin Seryl_tRNA_N PF02403.22 EJP69289.1 - 0.29 11.4 1.9 0.73 10.1 1.9 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Gar1 PF04410.14 EJP69290.1 - 9.5e-40 135.9 0.0 1.2e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 EJP69291.1 - 2.6e-14 53.8 0.4 2.6e-14 53.8 0.4 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NPP1 PF05630.11 EJP69292.1 - 1.6e-53 181.7 0.0 1.9e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Metallopep PF12044.8 EJP69293.1 - 5e-116 387.8 0.0 6.3e-116 387.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 EJP69293.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain Whi5 PF08528.11 EJP69294.1 - 2.1e-10 40.0 0.2 4e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 Whi5 like CcmD PF04995.14 EJP69295.1 - 0.0076 16.3 1.6 0.02 15.0 1.6 1.6 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) LPG_synthase_TM PF03706.13 EJP69295.1 - 0.032 13.8 0.1 0.045 13.3 0.1 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region DUF4328 PF14219.6 EJP69295.1 - 1.4 8.4 5.9 1.7 8.1 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4328) RNase_T PF00929.24 EJP69297.1 - 0.00016 22.3 0.0 0.0093 16.5 0.0 2.2 1 1 0 1 1 1 1 Exonuclease BTK PF00779.19 EJP69297.1 - 0.053 13.3 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 BTK motif Ribosomal_L36 PF00444.18 EJP69297.1 - 2.3 8.5 6.5 5.9 7.2 6.5 1.7 1 0 0 1 1 1 0 Ribosomal protein L36 Peptidase_C14 PF00656.22 EJP69298.1 - 5.6e-61 206.6 0.0 7.8e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain PAT1 PF09770.9 EJP69298.1 - 4.5 5.4 15.9 6.3 4.9 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cnn_1N PF07989.11 EJP69299.1 - 9.9e-25 86.5 5.2 9.9e-25 86.5 5.2 14.8 8 5 6 16 16 15 1 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 EJP69299.1 - 2.2e-21 76.2 3.9 2.2e-21 76.2 3.9 4.8 4 0 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Bacillus_HBL PF05791.11 EJP69299.1 - 0.0006 19.7 4.1 0.0006 19.7 4.1 8.0 5 1 1 8 8 8 2 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.11 EJP69299.1 - 0.0015 18.8 12.2 0.0015 18.8 12.2 11.5 1 1 7 10 10 9 4 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 EJP69299.1 - 0.0025 17.7 7.9 0.0025 17.7 7.9 9.6 2 2 6 9 9 8 3 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 EJP69299.1 - 0.0026 16.5 19.7 0.0026 16.5 19.7 6.3 2 1 3 5 5 5 3 AAA domain Tropomyosin_1 PF12718.7 EJP69299.1 - 0.0088 16.2 25.2 0.0088 16.2 25.2 10.8 2 2 8 10 10 10 1 Tropomyosin like DUF1664 PF07889.12 EJP69299.1 - 0.011 15.8 84.6 0.034 14.2 2.0 10.6 5 4 7 12 12 12 0 Protein of unknown function (DUF1664) HALZ PF02183.18 EJP69299.1 - 0.016 15.4 0.3 0.016 15.4 0.3 11.4 10 1 2 12 12 12 0 Homeobox associated leucine zipper Fez1 PF06818.15 EJP69299.1 - 0.06 13.8 153.8 0.025 15.0 22.1 8.9 2 2 6 10 10 10 0 Fez1 DUF3450 PF11932.8 EJP69299.1 - 6.1 6.1 131.5 0.58 9.4 15.1 9.7 4 2 5 9 9 9 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EJP69299.1 - 8.9 6.5 90.2 0.013 15.7 6.6 9.3 3 3 4 9 9 9 0 Fibrinogen alpha/beta chain family Transglut_core2 PF13369.6 EJP69300.1 - 8.6e-16 57.9 0.0 2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 EJP69300.1 - 6.8e-07 29.1 0.6 6.8e-07 29.1 0.6 1.8 2 0 0 2 2 2 1 F-box-like YccV-like PF08755.11 EJP69300.1 - 1.3e-06 28.8 0.0 5.8e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.33 EJP69300.1 - 0.00012 21.9 0.2 0.00025 20.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain Peptidase_C12 PF01088.21 EJP69301.1 - 1.6e-60 204.5 0.0 2.2e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Transcript_VP30 PF11507.8 EJP69301.1 - 0.078 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 Glyco_hydro_42M PF08532.10 EJP69301.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain I-set PF07679.16 EJP69302.1 - 0.018 15.1 0.1 18 5.5 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin I-set domain DUF1918 PF08940.11 EJP69302.1 - 0.13 11.9 2.5 36 4.1 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1918) Nrap_D5 PF17406.2 EJP69303.1 - 6.2e-59 198.4 0.1 5.8e-58 195.2 0.1 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 EJP69303.1 - 1.1e-58 198.1 0.3 2.7e-58 196.9 0.2 1.7 1 1 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 EJP69303.1 - 8.2e-49 165.3 0.3 3.1e-46 156.9 0.2 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 EJP69303.1 - 7.9e-48 162.4 0.9 1.7e-47 161.3 0.9 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EJP69303.1 - 8.1e-42 143.0 0.0 1.5e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EJP69303.1 - 5.5e-32 110.8 0.0 2.1e-31 108.9 0.0 2.0 2 0 0 2 2 2 1 Nrap protein domain 6 CoA_trans PF01144.23 EJP69304.1 - 2.2e-97 324.7 1.0 1.1e-59 201.4 0.1 2.2 2 0 0 2 2 2 2 Coenzyme A transferase PP28 PF10252.9 EJP69305.1 - 7e-28 96.9 16.9 7e-28 96.9 16.9 3.1 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 SURF6 PF04935.12 EJP69306.1 - 6.4e-45 153.4 30.5 6.4e-45 153.4 30.5 4.3 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 EJP69306.1 - 8.5e-16 58.3 0.7 8.5e-16 58.3 0.7 7.5 6 2 0 6 6 6 2 60S ribosome biogenesis protein Rrp14 GPP34 PF05719.11 EJP69307.1 - 2.4e-68 230.2 0.2 3e-68 229.9 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) GTP_EFTU PF00009.27 EJP69309.1 - 5.8e-35 120.6 5.1 2.4e-33 115.3 5.1 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EJP69309.1 - 2.5e-26 91.9 0.1 7.9e-26 90.2 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EJP69309.1 - 4.2e-11 42.9 1.3 1e-10 41.7 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP69309.1 - 5.4e-07 29.7 1.8 2.7e-05 24.1 0.2 2.5 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU_D2 PF03144.25 EJP69309.1 - 1.6e-06 28.4 4.0 0.0003 21.1 0.9 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Arf PF00025.21 EJP69309.1 - 2.7e-05 23.7 0.0 6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 EJP69309.1 - 0.00016 21.3 0.4 0.00042 19.9 0.4 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 EJP69309.1 - 0.00025 21.2 0.9 0.00086 19.5 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase IF2_N PF04760.15 EJP69309.1 - 0.00044 20.0 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.9 EJP69309.1 - 0.00063 19.5 0.2 0.0016 18.2 0.2 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EJP69309.1 - 0.00077 18.9 0.2 0.0022 17.5 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 EJP69309.1 - 0.0009 19.1 2.0 0.0036 17.2 0.9 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Dynamin_N PF00350.23 EJP69309.1 - 0.16 12.0 2.4 8.7 6.4 0.0 3.5 3 1 1 4 4 4 0 Dynamin family Ribo_biogen_C PF04034.13 EJP69310.1 - 5.5e-50 168.4 0.0 7.8e-50 167.9 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EJP69310.1 - 7.8e-13 48.0 0.6 1.7e-12 46.9 0.6 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VHS PF00790.19 EJP69311.1 - 9.5e-46 155.2 0.0 4.2e-45 153.1 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EJP69311.1 - 2.3e-19 69.5 0.7 5.2e-19 68.3 0.1 2.0 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.20 EJP69311.1 - 7.7e-17 61.6 0.0 7.7e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 EJP69311.1 - 2.4e-07 30.2 0.0 7.2e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 GGA N-GAT domain DUF3829 PF12889.7 EJP69311.1 - 0.16 11.4 4.1 0.27 10.7 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Ecl1 PF12855.7 EJP69311.1 - 4 8.6 14.9 8.7 7.5 14.9 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins HUN PF08729.10 EJP69312.1 - 1.9e-07 31.0 0.2 3.9e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Pyrid_ox_like PF16242.5 EJP69313.1 - 4.3e-24 84.8 0.0 6.4e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EJP69313.1 - 1.5e-08 34.7 0.0 2.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase eIF2A PF08662.11 EJP69314.1 - 3e-78 262.1 0.0 1e-77 260.4 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EJP69314.1 - 0.0078 17.0 0.0 99 4.1 0.0 5.0 3 2 1 5 5 5 0 WD domain, G-beta repeat RPAP1_C PF08620.10 EJP69315.1 - 2e-26 91.9 0.0 2e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EJP69315.1 - 1.2e-18 66.6 4.1 1.2e-18 66.6 4.1 1.8 2 0 0 2 2 2 1 RPAP1-like, N-terminal Metallophos PF00149.28 EJP69317.1 - 2.7e-11 44.4 0.2 4.7e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP69317.1 - 3.2e-05 24.2 0.0 0.00021 21.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.16 EJP69318.1 - 1.2e-37 129.7 42.3 9.3e-37 126.8 37.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP69318.1 - 6.8e-08 31.8 11.0 6.8e-08 31.8 11.0 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter CP2 PF04516.15 EJP69319.1 - 2e-79 266.1 0.0 3.1e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 EJP69319.1 - 0.0055 15.5 0.1 0.011 14.5 0.1 1.4 1 0 0 1 1 1 1 Tektin family Cep57_MT_bd PF06657.13 EJP69319.1 - 0.083 13.4 1.0 0.51 10.8 0.5 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HTH_23 PF13384.6 EJP69319.1 - 0.11 12.3 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_4 PF13613.6 EJP69319.1 - 0.2 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DivIC PF04977.15 EJP69319.1 - 0.27 11.0 1.0 0.7 9.7 1.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Acetyltransf_1 PF00583.25 EJP69320.1 - 4.8e-09 36.5 0.0 7e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP69320.1 - 7.5e-07 29.1 0.0 2.1e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP69320.1 - 9.6e-07 29.1 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJP69320.1 - 0.00055 20.0 0.0 0.059 13.4 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain baeRF_family10 PF18854.1 EJP69320.1 - 0.0053 17.0 1.4 0.0096 16.2 1.4 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF4407 PF14362.6 EJP69320.1 - 0.016 14.6 0.5 0.02 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FR47 PF08445.10 EJP69320.1 - 0.027 14.5 0.0 0.065 13.2 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein RNA_pol_Rpc4 PF05132.14 EJP69320.1 - 0.59 10.6 3.2 0.95 9.9 3.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Macoilin PF09726.9 EJP69320.1 - 3 6.3 4.6 4 5.9 4.6 1.1 1 0 0 1 1 1 0 Macoilin family HAD_SAK_1 PF10307.9 EJP69321.1 - 1.1e-73 247.4 0.0 1.9e-73 246.6 0.0 1.4 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins W2 PF02020.18 EJP69322.1 - 1.2e-20 73.5 1.8 1.2e-20 73.5 1.8 2.0 2 0 0 2 2 1 1 eIF4-gamma/eIF5/eIF2-epsilon TPR_1 PF00515.28 EJP69322.1 - 3e-17 61.6 10.3 0.0013 18.4 0.2 7.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EJP69322.1 - 1.8e-14 52.7 1.3 0.048 13.9 0.2 6.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJP69322.1 - 3.8e-14 53.1 31.0 1.4e-06 28.9 0.2 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP69322.1 - 7.3e-14 51.8 1.6 7.3e-14 51.8 1.6 4.3 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EJP69322.1 - 3e-13 48.8 26.5 0.018 15.1 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EJP69322.1 - 4.4e-12 45.5 1.3 0.0057 16.3 0.0 5.0 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 EJP69322.1 - 1e-10 41.5 36.8 2.2e-05 24.9 0.8 8.6 8 1 1 9 9 7 4 Tetratricopeptide repeat Hexapep PF00132.24 EJP69322.1 - 3.8e-10 39.1 14.9 1.5e-06 27.7 5.9 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EJP69322.1 - 2.5e-08 33.5 15.1 9.6e-05 22.0 8.1 3.4 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase TPR_19 PF14559.6 EJP69322.1 - 8e-08 32.7 22.2 0.00073 20.0 0.3 7.4 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJP69322.1 - 1.8e-07 31.3 15.3 1.7 9.0 0.3 7.0 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJP69322.1 - 4e-05 23.7 0.0 6.9 7.3 0.0 5.2 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP69322.1 - 0.0011 18.8 12.4 6.9 6.9 0.9 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat NTP_transferase PF00483.23 EJP69322.1 - 0.0025 17.4 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EJP69322.1 - 0.0032 17.9 0.0 0.014 15.8 0.0 2.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 EJP69322.1 - 0.0042 15.3 1.0 0.0064 14.7 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EJP69322.1 - 0.082 11.8 1.0 0.29 10.0 1.0 1.8 1 1 0 1 1 1 0 L-fucokinase TPR_9 PF13371.6 EJP69322.1 - 0.29 11.3 17.4 0.56 10.4 0.6 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJP69322.1 - 3.5 8.5 14.4 35 5.3 0.0 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 EJP69323.1 - 9e-29 100.0 0.2 1.6e-28 99.2 0.2 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EJP69323.1 - 7.4e-24 84.1 0.0 1.9e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain NPV_P10 PF05531.12 EJP69323.1 - 0.077 13.5 0.7 0.17 12.4 0.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.12 EJP69323.1 - 0.081 13.3 2.7 0.16 12.4 2.7 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) YabA PF06156.13 EJP69323.1 - 0.13 12.9 1.7 0.25 12.0 1.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DNA_primase_S PF01896.19 EJP69324.1 - 9.4e-63 211.4 0.2 1.4e-62 210.9 0.2 1.3 1 0 0 1 1 1 1 DNA primase small subunit tRNA_m1G_MT PF01746.21 EJP69325.1 - 5.8e-26 91.4 0.1 4.8e-19 68.8 0.0 2.4 2 1 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Tim17 PF02466.19 EJP69326.1 - 0.00071 19.9 7.9 0.0037 17.6 7.0 2.1 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 EJP69326.1 - 4.7 7.4 9.8 0.13 12.4 1.0 2.3 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide MutS_V PF00488.21 EJP69327.1 - 5.4e-83 277.7 0.2 8.3e-83 277.1 0.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EJP69327.1 - 1.2e-36 126.7 1.0 1.4e-35 123.2 0.7 2.7 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EJP69327.1 - 1e-25 90.6 0.9 1.7e-23 83.4 0.0 2.9 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 EJP69327.1 - 1.3e-17 64.0 0.0 7.4e-17 61.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EJP69327.1 - 8.5e-13 48.5 2.1 5.2e-12 45.9 1.6 2.6 2 0 0 2 2 2 1 MutS family domain IV Clusterin PF01093.17 EJP69327.1 - 0.011 14.8 0.4 0.019 14.0 0.4 1.4 1 0 0 1 1 1 0 Clusterin AAA_27 PF13514.6 EJP69327.1 - 0.044 13.4 0.1 0.17 11.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EJP69327.1 - 0.054 13.8 0.0 0.42 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Aspzincin_M35 PF14521.6 EJP69328.1 - 8.3e-12 45.9 0.0 1.7e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EJP69328.1 - 1.8e-05 23.8 1.0 2.5e-05 23.3 1.0 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family DUF4344 PF14247.6 EJP69328.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase Zip PF02535.22 EJP69329.1 - 2.3e-30 106.0 37.1 7.9e-13 48.3 7.9 3.4 3 1 1 4 4 4 3 ZIP Zinc transporter Kinesin PF00225.23 EJP69331.1 - 9e-82 274.7 0.0 1.2e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EJP69331.1 - 1.2e-22 80.4 0.0 2.7e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Antimicrobial22 PF16047.5 EJP69331.1 - 0.047 13.6 0.5 0.77 9.7 0.1 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide AIM24 PF01987.17 EJP69332.1 - 8.4e-50 169.4 0.0 1e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.16 EJP69333.1 - 1e-31 110.2 74.2 9.6e-28 97.1 45.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_8 PF13855.6 EJP69334.1 - 0.019 14.7 5.1 3.4 7.5 0.1 4.5 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 EJP69334.1 - 0.079 12.9 0.0 0.29 11.0 0.0 2.0 1 1 0 1 1 1 0 F-box-like CBS PF00571.28 EJP69335.1 - 1.5e-34 118.2 8.2 1e-08 35.4 0.0 5.9 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 EJP69335.1 - 6.9e-09 35.5 0.0 2.4e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 PB1 domain PBP1_TM PF14812.6 EJP69335.1 - 2.3 8.6 11.2 0.061 13.7 3.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cpn60_TCP1 PF00118.24 EJP69336.1 - 5.2e-153 510.2 6.3 6e-153 510.0 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FtsA PF14450.6 EJP69336.1 - 0.057 13.8 0.9 0.17 12.3 0.9 2.1 1 1 0 1 1 1 0 Cell division protein FtsA PNTB_4TM PF12769.7 EJP69336.1 - 0.11 13.0 0.0 0.47 10.9 0.0 2.1 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch zf-H2C2 PF09337.10 EJP69337.1 - 4.2e-15 55.7 2.3 9.8e-15 54.5 2.3 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EJP69337.1 - 9.2e-11 41.7 0.3 2.2e-10 40.5 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EJP69337.1 - 5.3e-05 23.4 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EJP69337.1 - 0.0094 16.1 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP69337.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Ribosomal_S2 PF00318.20 EJP69338.1 - 2e-61 207.0 0.0 5.1e-60 202.4 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S2 zf-C2H2 PF00096.26 EJP69339.1 - 1.6e-10 40.9 15.2 6.2e-05 23.2 4.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP69339.1 - 1e-07 32.0 9.7 0.0011 19.3 1.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP69339.1 - 2.6e-05 24.7 18.3 0.028 15.3 3.9 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EJP69339.1 - 0.017 14.8 6.2 0.25 11.1 1.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EJP69339.1 - 0.36 10.9 9.0 8.3 6.5 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger AT_hook PF02178.19 EJP69339.1 - 1.6 8.8 4.5 6.2 7.0 4.5 2.1 1 0 0 1 1 1 0 AT hook motif Cpn60_TCP1 PF00118.24 EJP69340.1 - 1.2e-160 535.4 2.8 1.3e-160 535.3 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 EJP69340.1 - 0.066 11.7 0.0 0.092 11.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like PDCD2_C PF04194.13 EJP69341.1 - 2.8e-44 151.3 3.6 2.6e-43 148.1 0.0 3.1 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Ndc1_Nup PF09531.10 EJP69341.1 - 0.75 8.4 6.4 0.91 8.1 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CSN8_PSD8_EIF3K PF10075.9 EJP69342.1 - 4.3e-38 130.5 0.0 6.4e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family FliG_M PF14841.6 EJP69342.1 - 0.098 12.9 0.0 1.7 8.9 0.0 2.6 3 0 0 3 3 3 0 FliG middle domain DUF4358 PF14270.6 EJP69342.1 - 0.12 12.6 0.3 24 5.3 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4358) DNA_ligase_A_M PF01068.21 EJP69343.1 - 6.4e-51 172.9 0.1 2.9e-48 164.2 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EJP69343.1 - 1.6e-34 119.7 0.0 3.2e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EJP69343.1 - 8.7e-18 64.8 0.1 6.6e-17 61.9 0.0 2.7 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EJP69343.1 - 0.0011 19.4 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 EJP69343.1 - 0.13 12.1 0.0 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Adaptin_N PF01602.20 EJP69344.1 - 2e-136 455.7 5.0 2.7e-136 455.2 5.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EJP69344.1 - 3.9e-62 209.1 3.6 9.8e-60 201.3 0.3 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJP69344.1 - 2e-16 60.1 0.9 1.8e-06 28.2 0.0 5.2 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.22 EJP69344.1 - 1.6e-12 46.6 4.8 0.0025 17.9 0.0 6.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 EJP69344.1 - 1.9e-05 25.0 0.1 0.29 11.7 0.0 5.0 3 1 1 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 EJP69344.1 - 0.00083 19.3 2.6 0.16 11.9 0.0 3.2 3 1 0 3 3 3 2 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 EJP69344.1 - 0.0016 18.6 0.6 0.065 13.4 0.0 3.6 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EJP69344.1 - 0.049 13.7 1.2 18 5.5 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EJP69344.1 - 0.059 12.9 0.1 2.1 7.9 0.0 3.0 3 1 1 4 4 4 0 CLASP N terminal BolA PF01722.18 EJP69345.1 - 3.7e-19 68.8 0.0 9.4e-19 67.5 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 EJP69346.1 - 8.4e-56 189.3 0.0 1e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) baeRF_family3 PF18845.1 EJP69346.1 - 0.17 12.1 0.6 0.36 11.1 0.2 1.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 Vps51 PF08700.11 EJP69347.1 - 2.6e-26 91.5 0.7 3.6e-26 91.0 0.0 1.6 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 EJP69347.1 - 0.00019 20.2 0.1 0.00024 19.9 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 EJP69347.1 - 0.0071 16.5 0.2 0.017 15.3 0.2 1.7 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Amidase PF01425.21 EJP69348.1 - 7.8e-06 25.1 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Amidase OPT PF03169.15 EJP69349.1 - 3.5e-141 471.9 38.2 4e-141 471.7 38.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Med12-LCEWAV PF12145.8 EJP69349.1 - 0.3 9.9 0.0 0.41 9.5 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain PPR_3 PF13812.6 EJP69349.1 - 0.52 10.4 2.0 0.97 9.6 0.1 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain RMI1_N PF08585.12 EJP69350.1 - 5.8e-56 189.7 0.0 6.6e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_1 PF00515.28 EJP69351.1 - 8.5e-33 110.8 22.2 0.0011 18.6 0.1 13.8 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_2 PF07719.17 EJP69351.1 - 7.1e-31 103.8 50.4 0.0011 19.0 0.2 16.7 19 0 0 19 19 16 9 Tetratricopeptide repeat TPR_16 PF13432.6 EJP69351.1 - 1.8e-30 105.3 27.2 0.00023 21.8 0.0 12.9 12 1 1 13 13 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 EJP69351.1 - 3.8e-28 97.8 27.0 0.00019 21.9 0.4 10.2 9 1 2 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 EJP69351.1 - 2.4e-24 83.5 28.8 0.14 12.4 0.0 14.4 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_14 PF13428.6 EJP69351.1 - 2.5e-23 80.7 33.4 0.026 15.3 0.0 15.8 14 4 4 18 18 14 6 Tetratricopeptide repeat TPR_11 PF13414.6 EJP69351.1 - 9.4e-20 70.0 24.3 0.0027 17.3 0.0 10.4 11 0 0 11 11 11 6 TPR repeat TPR_12 PF13424.6 EJP69351.1 - 1.2e-15 57.5 42.5 0.00068 19.9 0.2 12.7 12 2 3 15 15 13 6 Tetratricopeptide repeat TPR_17 PF13431.6 EJP69351.1 - 2.6e-14 52.5 14.3 0.13 12.7 0.0 13.9 17 0 0 17 17 16 3 Tetratricopeptide repeat TPR_7 PF13176.6 EJP69351.1 - 9.6e-13 47.2 27.4 0.0067 16.4 0.0 12.9 14 2 2 16 16 13 3 Tetratricopeptide repeat TPR_6 PF13174.6 EJP69351.1 - 9e-11 41.7 24.9 0.015 15.9 0.0 13.9 16 0 0 16 16 12 2 Tetratricopeptide repeat TPR_22 PF18833.1 EJP69351.1 - 2.2e-07 30.9 0.0 6.4e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EJP69351.1 - 1.1e-06 28.7 11.6 1.4 9.1 0.3 7.3 8 1 0 8 8 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EJP69351.1 - 8.2e-06 25.5 13.8 0.13 12.2 0.0 8.8 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EJP69351.1 - 2.2e-05 24.0 18.7 5.2e-05 22.8 0.2 5.5 5 2 0 5 5 5 1 MalT-like TPR region TPR_20 PF14561.6 EJP69351.1 - 0.0011 19.2 16.2 2.5 8.5 0.1 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP69351.1 - 0.0014 18.8 22.6 0.26 11.6 0.0 8.6 6 4 2 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 EJP69351.1 - 0.0046 17.6 9.2 11 6.9 0.1 6.7 6 1 0 6 6 6 0 Sel1 repeat HemY_N PF07219.13 EJP69351.1 - 0.0053 16.9 16.8 0.11 12.7 0.0 7.2 6 2 1 7 7 7 1 HemY protein N-terminus ChAPs PF09295.10 EJP69351.1 - 0.0087 15.1 0.8 4.5 6.2 0.0 3.9 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 EJP69351.1 - 0.034 14.2 8.7 32 4.7 0.0 7.1 9 0 0 9 9 7 0 Fis1 C-terminal tetratricopeptide repeat TPPII_N PF12583.8 EJP69351.1 - 0.046 14.3 0.0 7.3 7.2 0.0 3.4 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal DUF627 PF04781.12 EJP69351.1 - 0.11 12.5 5.2 14 5.8 1.3 3.9 3 1 0 3 3 2 0 Protein of unknown function (DUF627) PIN_9 PF18477.1 EJP69351.1 - 0.56 10.5 2.0 1.1 9.6 0.7 2.1 2 0 0 2 2 1 0 PIN like domain TPR_4 PF07721.14 EJP69351.1 - 0.71 10.7 13.3 3.8e+02 2.2 0.0 8.2 9 0 0 9 9 7 0 Tetratricopeptide repeat Glyco_hydro_5_C PF18564.1 EJP69352.1 - 2.8e-19 69.4 0.0 8.5e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EJP69352.1 - 1.8e-11 44.0 3.4 1.8e-07 30.9 1.1 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EJP69352.1 - 0.0015 17.9 0.2 0.088 12.1 0.1 2.1 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.19 EJP69352.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Pkinase PF00069.25 EJP69353.1 - 3.2e-62 210.3 0.0 5e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69353.1 - 2.4e-47 161.4 0.0 3.7e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP69353.1 - 6.9e-10 38.7 0.0 2.5e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EJP69353.1 - 0.0019 17.6 0.1 0.009 15.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EJP69353.1 - 0.0091 14.8 0.0 0.023 13.5 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EJP69353.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.20 EJP69354.1 - 3.9e-170 566.7 0.0 4.7e-170 566.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 EJP69354.1 - 0.031 13.8 0.9 0.47 9.9 0.3 2.6 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 Fig1 PF12351.8 EJP69355.1 - 6.1e-53 179.5 6.0 6.1e-53 179.5 6.0 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EJP69355.1 - 2.5e-07 30.5 12.9 4e-07 29.9 12.7 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 EJP69355.1 - 0.0026 16.9 7.4 0.0026 16.9 7.4 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) RINT1_TIP1 PF04437.13 EJP69356.1 - 3.6e-175 583.6 0.0 4.8e-175 583.2 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family HTH_53 PF18606.1 EJP69356.1 - 0.62 9.8 3.9 2.9 7.6 0.4 3.4 3 0 0 3 3 3 0 Zap helix turn helix N-terminal domain Mito_carr PF00153.27 EJP69357.1 - 6.5e-56 186.3 4.1 1.4e-19 69.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein GFA PF04828.14 EJP69357.1 - 6e-11 42.5 4.8 1.7e-06 28.3 0.5 2.8 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 EJP69357.1 - 0.0091 15.9 2.8 0.13 12.2 0.1 3.0 2 1 0 2 2 2 1 Nudix N-terminal NOB1_Zn_bind PF08772.11 EJP69357.1 - 0.048 13.8 3.0 0.57 10.4 0.0 2.9 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 EJP69357.1 - 0.39 10.5 4.0 0.8 9.5 0.5 2.9 2 0 0 2 2 2 0 zinc-ribbon domain Sec34 PF04136.15 EJP69358.1 - 1.1e-47 161.7 1.5 3.9e-47 159.9 1.5 2.1 1 0 0 1 1 1 1 Sec34-like family DUF512 PF04459.12 EJP69358.1 - 0.043 13.1 0.2 1.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF512) RCC1 PF00415.18 EJP69360.1 - 1.9e-25 89.3 2.7 9.8e-05 22.9 0.0 6.6 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EJP69360.1 - 1.6e-13 50.1 14.6 1.6e-08 34.1 0.0 7.1 8 0 0 8 8 8 2 Regulator of chromosome condensation (RCC1) repeat DUF1459 PF07312.11 EJP69360.1 - 0.057 13.6 0.1 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) Y_phosphatase PF00102.27 EJP69361.1 - 4.4e-46 157.4 0.0 6.1e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EJP69361.1 - 0.00042 20.1 0.1 0.0013 18.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EJP69361.1 - 0.0011 19.1 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EJP69361.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4914 PF16260.5 EJP69361.1 - 0.12 10.4 0.0 0.36 8.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4914) Prefoldin PF02996.17 EJP69364.1 - 5.9e-35 119.8 0.1 5.9e-35 119.8 0.1 2.0 3 0 0 3 3 3 1 Prefoldin subunit APG17 PF04108.12 EJP69364.1 - 0.006 15.7 2.7 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 Autophagy protein Apg17 FlaC_arch PF05377.11 EJP69364.1 - 0.0085 16.5 1.1 0.68 10.4 0.1 3.0 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 EJP69364.1 - 0.0088 16.0 9.7 0.015 15.2 0.0 3.2 1 1 1 3 3 3 1 Prefoldin subunit End3 PF12761.7 EJP69364.1 - 0.051 13.8 0.0 0.051 13.8 0.0 2.6 1 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 DUF1664 PF07889.12 EJP69364.1 - 0.067 13.2 0.5 6.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) VanZ PF04892.12 EJP69365.1 - 2.9e-09 37.6 3.3 4.6e-09 37.0 3.3 1.3 1 0 0 1 1 1 1 VanZ like family YfhO PF09586.10 EJP69365.1 - 0.02 13.2 0.8 0.024 12.9 0.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Phage_holin_2_4 PF16082.5 EJP69365.1 - 0.11 12.3 1.6 0.3 10.8 0.0 2.3 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like RseC_MucC PF04246.12 EJP69365.1 - 0.33 10.9 0.7 10 6.0 0.0 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC LapA_dom PF06305.11 EJP69365.1 - 4.3 7.2 5.4 12 5.7 0.0 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1993 PF09351.10 EJP69366.1 - 9.8e-42 142.8 0.0 1.1e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DinB PF05163.12 EJP69366.1 - 0.076 12.9 0.2 0.63 10.0 0.2 2.0 1 1 0 1 1 1 0 DinB family Amidase PF01425.21 EJP69367.1 - 3.2e-83 280.2 0.0 3.9e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Bromodomain PF00439.25 EJP69368.1 - 1.9e-19 69.5 0.2 4.7e-19 68.2 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EJP69368.1 - 2.2e-09 37.2 0.0 4.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.6 EJP69368.1 - 1.8 9.0 18.0 0.5 10.8 7.0 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MscL PF01741.18 EJP69369.1 - 3.7e-20 72.4 0.7 4.6e-20 72.1 0.7 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL MFS_1 PF07690.16 EJP69371.1 - 1.6e-36 126.0 32.9 1.6e-36 126.0 32.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP69371.1 - 7.6e-13 48.1 4.8 7.6e-13 48.1 4.8 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 EJP69371.1 - 0.18 12.0 5.5 0.11 12.8 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) MscL PF01741.18 EJP69371.1 - 0.29 11.4 1.8 1.8 8.9 0.1 2.7 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL DUF2976 PF11190.8 EJP69371.1 - 1.2 9.0 5.3 14 5.5 0.7 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) Rax2 PF12768.7 EJP69372.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Glyco_hydro_76 PF03663.14 EJP69373.1 - 6e-126 420.8 9.5 7.5e-126 420.5 9.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EJP69373.1 - 0.14 11.2 6.8 3.8 6.5 0.2 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.21 EJP69374.1 - 8.5e-62 209.4 0.0 1e-61 209.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EJP69374.1 - 0.039 12.8 0.0 0.059 12.2 0.0 1.3 1 1 0 1 1 1 0 Allinase DUF4911 PF16256.5 EJP69374.1 - 0.11 12.5 0.0 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4911) MitoNEET_N PF10660.9 EJP69375.1 - 0.006 16.6 0.7 0.006 16.6 0.7 2.2 3 0 0 3 3 3 1 Iron-containing outer mitochondrial membrane protein N-terminus DUF3619 PF12279.8 EJP69375.1 - 0.08 13.3 0.1 0.38 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Lipase_GDSL PF00657.22 EJP69377.1 - 7.5e-09 35.8 0.0 9.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EJP69377.1 - 2.5e-05 24.8 0.6 4.5e-05 23.9 0.6 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PNP_phzG_C PF10590.9 EJP69378.1 - 3.6e-20 71.8 2.2 9e-20 70.5 2.2 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EJP69378.1 - 6.5e-18 64.7 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin_N PF00134.23 EJP69379.1 - 4e-07 29.8 0.0 3.8e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Utp14 PF04615.13 EJP69381.1 - 0.011 14.3 18.9 0.013 14.2 18.9 1.0 1 0 0 1 1 1 0 Utp14 protein Presenilin PF01080.17 EJP69381.1 - 0.037 12.8 17.5 0.047 12.5 17.5 1.2 1 0 0 1 1 1 0 Presenilin Acatn PF13000.7 EJP69381.1 - 0.056 11.9 0.6 0.081 11.4 0.2 1.4 1 1 0 1 1 1 0 Acetyl-coenzyme A transporter 1 LAP1C PF05609.12 EJP69381.1 - 0.31 10.1 13.3 0.35 9.9 13.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 EJP69381.1 - 0.34 10.1 8.0 0.48 9.6 8.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 EJP69381.1 - 0.38 9.7 17.0 0.49 9.4 17.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 EJP69381.1 - 0.84 9.1 14.8 0.93 9.0 14.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 EJP69381.1 - 1.5 7.3 14.6 1.6 7.2 14.6 1.0 1 0 0 1 1 1 0 Macoilin family Suf PF05843.14 EJP69381.1 - 3.5 7.5 11.3 4.2 7.3 11.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Raftlin PF15250.6 EJP69381.1 - 4.6 5.9 15.2 5.9 5.5 15.2 1.1 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.16 EJP69381.1 - 6.3 6.8 12.8 25 4.8 12.8 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 EJP69381.1 - 7.4 6.5 15.6 11 6.0 15.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 EJP69381.1 - 8 6.2 17.6 12 5.6 17.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Metallophos PF00149.28 EJP69382.1 - 1.7e-31 110.3 0.1 2.5e-22 80.4 0.0 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EJP69382.1 - 0.17 12.3 0.1 0.45 11.0 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain SUIM_assoc PF16619.5 EJP69383.1 - 0.01 15.9 11.0 0.3 11.2 3.1 2.9 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_S58 PF03576.14 EJP69384.1 - 5.5e-114 380.7 6.7 9.1e-114 380.0 6.7 1.3 1 0 0 1 1 1 1 Peptidase family S58 Cupredoxin_1 PF13473.6 EJP69384.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 Cupredoxin-like domain AFG1_ATPase PF03969.16 EJP69385.1 - 8.2e-96 321.0 0.0 6.5e-91 304.9 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EJP69385.1 - 0.00059 20.3 0.0 0.26 11.6 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 EJP69385.1 - 0.0017 18.4 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 EJP69385.1 - 0.0051 16.7 0.0 1.5 8.6 0.1 2.6 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 EJP69385.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EJP69385.1 - 0.038 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EJP69385.1 - 0.05 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EJP69385.1 - 0.056 14.0 0.0 1.7 9.1 0.0 2.7 3 0 0 3 3 3 0 ABC transporter APS_kinase PF01583.20 EJP69385.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SH3_9 PF14604.6 EJP69386.1 - 1.7e-11 43.8 0.0 2.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EJP69386.1 - 3.7e-07 29.6 0.0 5.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EJP69386.1 - 5.8e-05 22.7 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain TNFR_16_TM PF18422.1 EJP69386.1 - 0.025 14.5 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF5305 PF17231.2 EJP69386.1 - 0.066 12.6 0.2 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Podoplanin PF05808.11 EJP69386.1 - 0.27 11.4 7.1 1 9.4 7.1 1.9 1 1 0 1 1 1 0 Podoplanin TFIIIC_delta PF12657.7 EJP69387.1 - 4.1e-18 66.0 0.0 1.7e-17 64.0 0.0 2.1 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-LITAF-like PF10601.9 EJP69387.1 - 9.3e-18 64.3 7.8 2.4e-17 62.9 7.8 1.7 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-TFIIIC PF12660.7 EJP69387.1 - 1.4e-08 34.6 0.7 1.4e-08 34.6 0.7 2.2 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex DUF899 PF05988.12 EJP69388.1 - 1.8e-67 227.0 0.1 2.1e-67 226.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.21 EJP69388.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Peptidase_C13 PF01650.18 EJP69389.1 - 3.7e-41 141.3 0.2 4.8e-41 141.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family TEX12 PF15219.6 EJP69389.1 - 0.11 12.8 0.6 0.71 10.2 0.1 2.4 2 0 0 2 2 2 0 Testis-expressed 12 VSP PF03302.13 EJP69390.1 - 0.016 14.1 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.11 EJP69390.1 - 0.027 14.6 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Podoplanin POB3_N PF17292.2 EJP69390.1 - 0.078 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 POB3-like N-terminal PH domain LapA_dom PF06305.11 EJP69390.1 - 0.31 10.9 0.6 1.5 8.7 0.3 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain His_Phos_1 PF00300.22 EJP69391.1 - 1.6e-06 28.0 0.2 0.0071 16.0 0.0 3.5 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Mcm10 PF09332.11 EJP69391.1 - 0.071 12.5 1.7 0.11 12.0 1.7 1.1 1 0 0 1 1 1 0 Mcm10 replication factor adh_short PF00106.25 EJP69392.1 - 1.3e-83 279.2 12.3 4e-44 150.4 2.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EJP69392.1 - 3.9e-68 229.5 1.8 4.4e-36 124.6 0.2 2.7 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EJP69392.1 - 9.9e-33 112.3 0.0 2.3e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EJP69392.1 - 1.8e-29 102.9 2.8 1.2e-13 51.3 0.2 2.8 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 EJP69392.1 - 0.00014 22.0 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase FAM25 PF15825.5 EJP69392.1 - 0.044 14.1 5.0 0.71 10.3 1.1 2.8 2 0 0 2 2 2 0 FAM25 family PglL_A PF15864.5 EJP69392.1 - 1.3 8.8 6.6 10 6.0 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase SRP54 PF00448.22 EJP69393.1 - 2.4e-07 30.6 0.0 3.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PRK PF00485.18 EJP69393.1 - 1.7e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.14 EJP69393.1 - 3.6e-05 23.2 0.0 8.1e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 KAP family P-loop domain MeaB PF03308.16 EJP69393.1 - 7.9e-05 21.8 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EJP69393.1 - 9.4e-05 22.9 0.0 0.00013 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EJP69393.1 - 0.00059 19.2 0.0 0.00087 18.6 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.19 EJP69393.1 - 0.00085 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EJP69393.1 - 0.0026 17.5 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EJP69393.1 - 0.0031 17.2 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase APS_kinase PF01583.20 EJP69393.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase MobB PF03205.14 EJP69393.1 - 0.0089 15.9 0.0 0.022 14.6 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B LpxK PF02606.14 EJP69393.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase CBP_BcsQ PF06564.12 EJP69393.1 - 0.032 13.7 0.5 0.055 12.9 0.1 1.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ TsaE PF02367.17 EJP69393.1 - 0.036 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EJP69393.1 - 0.042 14.4 0.0 0.1 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain CbiA PF01656.23 EJP69393.1 - 0.046 13.8 0.3 0.072 13.1 0.3 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EJP69393.1 - 0.049 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EJP69393.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJP69393.1 - 0.071 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EJP69393.1 - 0.073 13.6 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EJP69393.1 - 0.083 12.8 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 EJP69393.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EJP69393.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 EJP69393.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 EJP69393.1 - 0.21 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EJP69393.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ECM11 PF15463.6 EJP69394.1 - 4.7e-38 130.8 3.4 4.7e-38 130.8 3.4 2.9 3 0 0 3 3 3 1 Extracellular mutant protein 11 CDC45 PF02724.14 EJP69395.1 - 1.3e-245 816.6 0.0 1.9e-245 816.1 0.0 1.4 1 1 0 1 1 1 1 CDC45-like protein CSRNP_N PF16019.5 EJP69395.1 - 0.42 10.5 1.9 0.88 9.4 1.9 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus NPR3 PF03666.13 EJP69395.1 - 5.1 5.8 5.1 9.1 4.9 5.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RHS_repeat PF05593.14 EJP69397.1 - 4.4e-05 23.9 46.2 0.027 15.0 0.1 13.2 13 2 2 15 15 15 5 RHS Repeat RNase_P_Rpp14 PF01900.19 EJP69398.1 - 2.1e-38 130.7 0.0 2.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 EJP69399.1 - 6.3e-77 258.6 0.2 9.8e-77 258.0 0.0 1.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EJP69399.1 - 0.0045 16.0 0.2 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 EJP69399.1 - 0.013 15.5 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EJP69399.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EJP69399.1 - 0.096 11.9 1.0 0.39 10.0 0.0 2.4 3 1 1 4 4 4 0 Zeta toxin AAA_33 PF13671.6 EJP69399.1 - 0.22 11.7 0.3 0.55 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EJP69399.1 - 0.6 10.5 0.1 0.6 10.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EJP69399.1 - 0.87 10.1 2.6 2.2 8.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain cNMP_binding PF00027.29 EJP69400.1 - 4.4e-28 97.2 3.2 1.3e-15 57.2 0.1 5.8 6 0 0 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 EJP69400.1 - 1.1e-15 58.3 6.2 1.3e-14 54.9 6.2 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Pyridoxal_deC PF00282.19 EJP69401.1 - 4.5e-94 315.2 0.0 1.3e-93 313.7 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain EMP70 PF02990.16 EJP69402.1 - 5.3e-205 682.0 1.7 6.9e-205 681.6 1.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 EJP69402.1 - 5.6e-08 32.1 6.2 5.6e-08 32.1 6.2 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Bul1_C PF04426.12 EJP69403.1 - 3.4e-07 30.0 0.0 3.1e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Bul1 C terminus Bul1_N PF04425.12 EJP69403.1 - 4.2e-05 22.5 0.8 0.013 14.3 0.2 2.8 2 1 1 3 3 3 2 Bul1 N terminus Arrestin_N PF00339.29 EJP69403.1 - 0.053 13.6 0.2 0.16 12.0 0.2 1.9 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 EJP69403.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein tRNA-synt_1 PF00133.22 EJP69404.1 - 1.4e-149 499.1 0.0 2.1e-149 498.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EJP69404.1 - 2.2e-20 72.8 0.0 4.4e-13 48.7 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EJP69404.1 - 1.5e-12 47.7 0.0 2.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 EJP69404.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 EJP69404.1 - 0.16 11.8 3.4 0.4 10.6 3.4 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Tom37 PF10568.9 EJP69409.1 - 5.5e-37 126.9 0.2 1.1e-36 125.8 0.1 1.6 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EJP69409.1 - 4.5e-07 30.5 0.0 2.3e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EJP69409.1 - 5.6e-06 26.1 0.0 1.9e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PIG-U PF06728.13 EJP69410.1 - 1.1e-120 403.2 22.8 1.3e-120 403.0 22.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 EJP69410.1 - 2.2 8.0 6.2 3.5 7.3 5.2 1.7 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 EJP69411.1 - 1.2e-120 402.2 0.0 1.2e-120 402.2 0.0 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus Nop53 PF07767.11 EJP69411.1 - 0.0015 18.0 30.6 0.0015 18.0 30.6 1.7 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) BRCT_2 PF16589.5 EJP69411.1 - 0.0028 18.1 0.1 0.01 16.2 0.1 2.0 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF4719 PF15843.5 EJP69411.1 - 0.25 11.4 0.4 0.51 10.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) SDA1 PF05285.12 EJP69411.1 - 0.26 10.6 39.2 0.016 14.7 34.0 1.7 2 0 0 2 2 2 0 SDA1 SGT1 PF07093.11 EJP69411.1 - 0.54 8.6 18.0 0.85 8.0 18.0 1.2 1 0 0 1 1 1 0 SGT1 protein Astro_capsid_p PF12226.8 EJP69411.1 - 5.9 5.9 29.7 0.022 13.9 20.1 1.8 2 1 1 3 3 3 0 Turkey astrovirus capsid protein RRN9 PF10680.9 EJP69412.1 - 1.8e-18 66.6 0.2 1.8e-18 66.6 0.2 2.6 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.26 EJP69412.1 - 0.14 12.7 0.2 0.33 11.5 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Kinesin PF00225.23 EJP69413.1 - 1.3e-109 366.2 0.9 1.3e-109 366.2 0.9 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EJP69413.1 - 1.6e-26 93.1 0.4 6.9e-26 91.0 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 EJP69413.1 - 2.2e-05 24.9 0.8 2.2e-05 24.9 0.8 5.3 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 EJP69413.1 - 2.4 8.2 32.3 0.8 9.7 0.3 6.4 2 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 EJP69414.1 - 1.9e-49 168.5 50.0 2.7e-48 164.7 51.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJP69414.1 - 1.3e-22 80.0 15.4 1.3e-22 80.0 15.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EJP69414.1 - 1.9e-15 56.7 7.9 1.9e-15 56.7 7.9 3.4 2 1 0 3 3 3 2 Sugar (and other) transporter UPF0183 PF03676.14 EJP69415.1 - 3.9e-59 200.9 0.0 1.1e-33 117.1 0.0 3.5 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) DUF3712 PF12505.8 EJP69416.1 - 3.2e-16 59.7 0.6 7.4e-16 58.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EJP69416.1 - 0.0033 17.9 0.3 0.039 14.5 0.1 2.3 2 0 0 2 2 2 1 Late embryogenesis abundant protein HECT PF00632.25 EJP69416.1 - 0.023 14.2 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Presenilin PF01080.17 EJP69416.1 - 0.053 12.3 1.6 0.078 11.7 1.6 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EJP69416.1 - 0.11 11.1 1.1 0.13 10.8 1.1 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 EJP69416.1 - 0.22 9.8 2.0 0.3 9.3 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 EJP69416.1 - 8 5.1 7.2 12 4.5 7.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BTB PF00651.31 EJP69417.1 - 2e-13 50.5 0.0 6.8e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain zf-dskA_traR PF01258.17 EJP69417.1 - 0.0059 16.5 0.7 0.01 15.7 0.7 1.4 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger DUF2127 PF09900.9 EJP69417.1 - 0.033 14.4 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) zinc_ribbon_4 PF13717.6 EJP69417.1 - 2.3 8.2 6.4 15 5.6 6.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain F-box-like PF12937.7 EJP69418.1 - 3.4e-05 23.7 0.2 8.2e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP69418.1 - 0.0079 16.1 0.5 0.022 14.6 0.5 1.8 1 0 0 1 1 1 1 F-box domain FAD-oxidase_C PF02913.19 EJP69422.1 - 2.5e-42 145.3 0.1 1.2e-29 103.7 0.0 2.3 2 0 0 2 2 2 2 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EJP69422.1 - 1.1e-35 122.3 0.0 2.6e-35 121.2 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Metal_resist PF13801.6 EJP69422.1 - 0.023 14.9 0.3 12 6.2 0.0 2.8 3 0 0 3 3 3 0 Heavy-metal resistance Clr5 PF14420.6 EJP69423.1 - 1.7e-21 76.2 0.5 1.7e-21 76.2 0.5 2.7 3 0 0 3 3 3 1 Clr5 domain ECH_1 PF00378.20 EJP69424.1 - 1.2e-39 136.1 0.0 1.6e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP69424.1 - 5.6e-22 78.7 0.1 1.2e-20 74.3 0.1 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase DAN PF03045.15 EJP69424.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 DAN domain MAJIN PF15077.6 EJP69425.1 - 0.13 12.0 5.9 0.29 10.9 5.9 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein Selenoprotein_S PF06936.11 EJP69425.1 - 1.4 8.7 8.8 2.3 8.0 8.8 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) DPPIV_N PF00930.21 EJP69426.1 - 6e-22 77.9 0.0 4.3e-20 71.8 0.0 2.4 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region VHL PF01847.16 EJP69426.1 - 0.029 14.3 0.5 0.074 13.0 0.1 1.9 2 0 0 2 2 2 0 VHL beta domain Glyco_tranf_2_3 PF13641.6 EJP69427.1 - 1.2e-24 87.4 0.0 1.8e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EJP69427.1 - 5.4e-06 26.3 0.0 1.5e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EJP69427.1 - 5.7e-06 25.9 0.0 1.3e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 RdgC PF04381.12 EJP69427.1 - 0.23 10.7 0.5 0.36 10.1 0.5 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC GWT1 PF06423.12 EJP69429.1 - 1.5e-42 145.2 3.1 1.5e-42 145.2 3.1 2.2 2 1 1 3 3 3 1 GWT1 DUF4818 PF16089.5 EJP69429.1 - 0.28 11.7 4.0 3.7 8.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4818) APH PF01636.23 EJP69430.1 - 1.7e-22 80.5 0.0 2.4e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EJP69430.1 - 2.6e-05 23.9 0.0 0.0053 16.4 0.0 2.1 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.20 EJP69430.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 EJP69430.1 - 0.037 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 EJP69431.1 - 1e-60 205.3 0.0 1.7e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69431.1 - 5.1e-35 121.0 0.0 1.3e-29 103.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EJP69431.1 - 3.9e-06 26.4 0.0 0.00073 18.9 0.0 2.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EJP69431.1 - 4.9e-06 26.7 0.0 9.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EJP69431.1 - 0.027 13.4 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EJP69431.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 EJP69432.1 - 2.2e-33 115.7 0.0 1e-16 61.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP69432.1 - 1.1e-11 44.9 26.4 2.1e-09 37.4 0.8 3.8 2 2 1 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 EJP69432.1 - 3.3e-06 27.1 0.1 3.3 7.4 0.0 4.2 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EJP69432.1 - 0.00059 20.3 0.0 0.048 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EJP69432.1 - 0.00082 19.2 0.2 0.016 14.9 0.1 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase SMC_N PF02463.19 EJP69432.1 - 0.0065 15.9 0.1 6.8 6.0 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EJP69432.1 - 0.0073 15.4 0.0 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EJP69432.1 - 0.021 14.9 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EJP69432.1 - 0.049 13.9 0.6 1.2 9.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EJP69432.1 - 0.055 13.7 0.2 1.3 9.3 0.1 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EJP69432.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Dynamin_N PF00350.23 EJP69432.1 - 0.068 13.2 0.5 0.38 10.8 0.1 2.3 2 0 0 2 2 2 0 Dynamin family AAA PF00004.29 EJP69432.1 - 0.082 13.3 0.3 0.57 10.6 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EJP69432.1 - 0.17 12.1 0.1 0.91 9.8 0.1 2.2 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EJP69432.1 - 0.19 11.0 0.0 0.95 8.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Glyco_hydro_42 PF02449.15 EJP69433.1 - 0.00017 21.0 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase Na_Ca_ex PF01699.24 EJP69434.1 - 7.4e-38 129.9 39.8 2.6e-20 72.9 19.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3087 PF11286.8 EJP69434.1 - 0.16 11.5 0.3 0.43 10.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF872 PF05915.12 EJP69434.1 - 7.2 6.8 7.2 5.4 7.2 0.1 3.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) SPRY PF00622.28 EJP69435.1 - 8.7e-06 25.8 0.6 2.9e-05 24.2 0.0 2.0 2 1 0 2 2 2 1 SPRY domain PPP4R2 PF09184.11 EJP69436.1 - 1.6e-05 24.7 0.0 1.6e-05 24.7 0.0 4.0 3 1 0 4 4 4 2 PPP4R2 TFIIA PF03153.13 EJP69436.1 - 0.34 10.8 31.4 0.15 12.1 24.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ORC6 PF05460.13 EJP69436.1 - 3.1 7.0 26.4 0.27 10.5 10.5 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) AAA_23 PF13476.6 EJP69437.1 - 6.2e-16 59.5 136.9 4.5e-13 50.2 73.4 7.9 1 1 0 2 2 1 1 AAA domain AAA_21 PF13304.6 EJP69437.1 - 7e-08 32.6 0.7 0.00013 21.9 0.6 4.0 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EJP69437.1 - 1.8e-06 28.1 0.0 8.5e-06 25.9 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EJP69437.1 - 0.0022 17.7 0.0 0.0069 16.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain ARTD15_N PF18084.1 EJP69437.1 - 0.023 14.9 2.8 0.23 11.7 0.1 4.0 3 1 0 3 3 3 0 ARTD15 N-terminal domain AAA_16 PF13191.6 EJP69437.1 - 0.054 13.9 0.0 0.054 13.9 0.0 6.1 4 2 0 4 4 2 0 AAA ATPase domain ABC_tran PF00005.27 EJP69437.1 - 0.083 13.4 0.0 0.083 13.4 0.0 7.7 3 2 1 4 4 2 0 ABC transporter AAA_33 PF13671.6 EJP69437.1 - 0.1 12.8 0.0 0.1 12.8 0.0 4.6 5 1 0 5 5 5 0 AAA domain AAA_22 PF13401.6 EJP69437.1 - 0.19 12.0 0.1 0.19 12.0 0.1 5.1 3 2 0 3 3 2 0 AAA domain SMC_N PF02463.19 EJP69437.1 - 3.3 7.1 62.7 53 3.1 62.7 3.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 EJP69437.1 - 6.6 5.2 126.3 0.19 10.4 0.1 7.2 1 1 2 6 6 6 0 AAA domain GATA PF00320.27 EJP69438.1 - 6e-16 57.8 5.4 1.1e-15 57.0 5.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 EJP69438.1 - 7.8e-12 45.3 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EJP69438.1 - 3.3e-05 23.8 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EJP69438.1 - 0.0034 17.6 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 PAS fold Zn-ribbon_8 PF09723.10 EJP69438.1 - 0.0091 16.1 0.2 0.021 14.9 0.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain PAS_11 PF14598.6 EJP69438.1 - 0.042 14.0 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain SH3_4 PF06347.13 EJP69438.1 - 0.078 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain TF_Zn_Ribbon PF08271.12 EJP69438.1 - 0.19 11.3 0.8 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 EJP69438.1 - 5 7.1 5.9 0.84 9.6 0.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Fungal_trans PF04082.18 EJP69439.1 - 1.2e-16 60.5 0.3 3.2e-16 59.2 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Macoilin PF09726.9 EJP69440.1 - 6.3 5.2 8.6 6.3 5.2 8.6 1.1 1 0 0 1 1 1 0 Macoilin family Amidase PF01425.21 EJP69441.1 - 6.6e-58 196.7 0.1 1.6e-57 195.5 0.1 1.6 1 1 0 1 1 1 1 Amidase tRNA-synt_1d PF00750.19 EJP69442.1 - 5.8e-102 341.2 4.4 8.3e-102 340.7 4.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EJP69442.1 - 5.8e-31 107.1 0.2 2.1e-30 105.3 0.2 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EJP69442.1 - 0.0073 16.9 0.0 0.022 15.3 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF2203 PF09969.9 EJP69442.1 - 2.2 9.0 4.9 1.1 10.0 0.3 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) FMO-like PF00743.19 EJP69443.1 - 2.4e-36 125.3 0.0 1.6e-22 79.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP69443.1 - 6.4e-13 48.6 0.6 2.7e-08 33.5 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP69443.1 - 6.1e-11 42.1 0.1 2.2e-10 40.2 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP69443.1 - 3.6e-08 33.0 0.1 2e-05 23.9 0.1 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 EJP69443.1 - 6.2e-08 32.8 0.0 1.7e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EJP69443.1 - 1.7e-07 31.4 0.7 0.00035 20.6 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EJP69443.1 - 1.9e-07 31.0 4.9 0.0017 18.0 0.3 3.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EJP69443.1 - 2e-07 30.5 0.7 8.3e-06 25.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) MCRA PF06100.11 EJP69443.1 - 6.1e-05 22.0 0.0 0.00039 19.3 0.0 1.9 2 0 0 2 2 2 1 MCRA family FAD_binding_2 PF00890.24 EJP69443.1 - 0.024 13.7 1.3 0.061 12.4 1.2 1.7 1 1 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 EJP69443.1 - 0.052 12.8 0.1 0.45 9.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EJP69443.1 - 0.14 10.8 0.7 0.27 9.9 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Luteo_P1-P2 PF08467.10 EJP69443.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Shikimate_DH PF01488.20 EJP69443.1 - 0.21 11.6 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RabGAP-TBC PF00566.18 EJP69444.1 - 0.036 13.7 0.3 0.036 13.7 0.3 1.6 2 0 0 2 2 2 0 Rab-GTPase-TBC domain CLTH PF10607.9 EJP69445.1 - 5.9e-32 110.6 0.0 2.5e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EJP69445.1 - 2.6e-07 30.5 4.5 4.9e-07 29.7 4.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EJP69445.1 - 0.0001 22.2 4.0 0.00018 21.4 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EJP69445.1 - 0.00013 21.8 4.1 0.00023 21.0 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EJP69445.1 - 0.00045 19.7 0.1 0.00077 18.9 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 EJP69445.1 - 0.0011 18.8 4.9 0.0019 18.0 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EJP69445.1 - 0.0011 18.7 5.6 0.0022 17.8 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP69445.1 - 0.0015 18.8 4.9 0.0027 18.0 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJP69445.1 - 0.042 13.7 5.4 0.1 12.5 5.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EJP69445.1 - 0.23 11.3 3.7 0.54 10.1 3.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cwf_Cwc_15 PF04889.12 EJP69445.1 - 0.28 10.9 5.4 0.41 10.3 5.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C3HC4_4 PF15227.6 EJP69445.1 - 1 9.6 5.8 2.1 8.6 5.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PG_binding_1 PF01471.18 EJP69446.1 - 0.018 15.2 0.0 2.7 8.3 0.0 3.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Baculo_PEP_C PF04513.12 EJP69446.1 - 0.026 14.6 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EJP69446.1 - 0.062 12.2 2.1 0.099 11.5 2.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1192 PF06698.11 EJP69446.1 - 0.07 13.2 0.2 0.23 11.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Tropomyosin_1 PF12718.7 EJP69446.1 - 0.085 13.0 2.4 0.1 12.7 0.8 1.8 1 1 1 2 2 2 0 Tropomyosin like FPP PF05911.11 EJP69446.1 - 0.25 9.5 4.7 0.37 8.9 4.7 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Jnk-SapK_ap_N PF09744.9 EJP69446.1 - 0.25 11.6 3.0 0.44 10.7 3.0 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 EJP69446.1 - 3.9 8.2 7.8 3.8 8.2 2.0 3.1 3 0 0 3 3 3 0 SlyX zf-Tim10_DDP PF02953.15 EJP69447.1 - 2.5e-20 71.9 1.9 2.9e-20 71.7 1.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Zn_clus PF00172.18 EJP69449.1 - 5.7e-06 26.4 9.7 5.7e-06 26.4 9.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP69449.1 - 0.00017 20.7 1.0 0.00061 18.9 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain GATase PF00117.28 EJP69451.1 - 1.4e-07 31.5 0.0 6.6e-05 22.8 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferase class-I PAD PF03068.15 EJP69452.1 - 1.3e-110 370.1 0.0 2.8e-110 369.0 0.0 1.5 1 1 0 1 1 1 1 Protein-arginine deiminase (PAD) EF-hand_5 PF13202.6 EJP69452.1 - 0.083 12.4 0.1 0.34 10.5 0.1 2.1 1 0 0 1 1 1 0 EF hand Glyco_hydro_47 PF01532.20 EJP69453.1 - 2e-110 369.8 0.0 2.6e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.27 EJP69454.1 - 1.7e-17 63.4 0.0 2.3e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EJP69454.1 - 0.0042 16.5 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Na_Ca_ex PF01699.24 EJP69455.1 - 6.6e-30 104.1 27.0 2.6e-15 56.7 9.6 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CD225 PF04505.12 EJP69455.1 - 0.32 11.1 3.3 0.37 11.0 0.2 2.8 2 1 0 2 2 2 0 Interferon-induced transmembrane protein DUF420 PF04238.12 EJP69455.1 - 7.9 6.8 10.4 1.9 8.8 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF420) Na_Ca_ex PF01699.24 EJP69456.1 - 2.2e-14 53.7 36.4 3.3e-08 33.6 11.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 EJP69457.1 - 5.1e-34 117.4 44.5 8e-20 71.3 16.1 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cad PF03596.13 EJP69458.1 - 4.8e-26 91.9 4.5 4.8e-26 91.9 4.5 1.4 2 0 0 2 2 2 1 Cadmium resistance transporter DUF3188 PF11384.8 EJP69458.1 - 0.0083 15.8 0.2 3.8 7.3 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3188) DUF2053 PF09767.9 EJP69458.1 - 0.2 11.8 4.8 1.8 8.7 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2053) Lgl_C PF08596.10 EJP69460.1 - 3.4e-120 401.4 0.0 5.3e-120 400.7 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EJP69460.1 - 9.4e-06 26.3 0.5 0.0074 17.1 0.1 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP69460.1 - 0.012 15.9 0.0 1.1 9.6 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Piwi PF02171.17 EJP69461.1 - 1.2e-82 277.6 0.0 1.8e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EJP69461.1 - 1e-17 65.0 0.1 2.6e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 EJP69461.1 - 3.9e-13 49.4 0.0 7.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 EJP69461.1 - 5.1e-12 45.3 0.0 2.5e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EJP69461.1 - 1.5e-09 38.0 0.0 3.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EJP69461.1 - 0.00061 20.0 0.1 0.0017 18.6 0.1 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Suf PF05843.14 EJP69462.1 - 2.6e-82 277.2 10.8 4.3e-82 276.4 0.3 4.3 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EJP69462.1 - 0.0001 22.8 0.8 0.2 12.6 0.0 5.4 5 1 2 7 7 7 1 Tetratricopeptide repeat HrpJ PF07201.11 EJP69462.1 - 0.25 11.6 5.4 2.5 8.4 0.0 4.0 4 1 0 4 4 4 0 HrpJ-like domain ASF1_hist_chap PF04729.13 EJP69463.1 - 4.7e-73 244.2 0.1 6.1e-73 243.8 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RasGAP PF00616.19 EJP69464.1 - 3e-59 200.2 0.2 1.1e-58 198.3 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EJP69464.1 - 3.9e-30 104.8 4.6 3.9e-30 104.8 4.6 2.4 2 0 0 2 2 2 1 RasGAP C-terminus Redoxin PF08534.10 EJP69465.1 - 5.3e-24 84.6 0.0 6.2e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EJP69465.1 - 2.4e-05 24.3 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family IBR PF01485.21 EJP69466.1 - 7.3e-23 80.6 45.7 3.9e-12 46.2 6.4 4.7 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EJP69466.1 - 0.00054 19.8 5.4 0.00054 19.8 5.4 5.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP69466.1 - 0.0018 18.6 6.8 0.0018 18.6 6.8 4.6 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJP69466.1 - 0.012 15.4 5.0 0.012 15.4 5.0 5.0 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) KCT2 PF17818.1 EJP69466.1 - 0.018 15.2 3.5 0.029 14.5 2.7 1.7 2 0 0 2 2 2 0 Keratinocyte-associated gene product zf-RING_UBOX PF13445.6 EJP69466.1 - 0.018 15.0 4.3 0.018 15.0 4.3 4.7 4 0 0 4 4 4 0 RING-type zinc-finger XPG_N PF00752.17 EJP69467.1 - 1.9e-24 86.1 0.0 3.5e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EJP69467.1 - 9.6e-24 83.6 0.0 2.4e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EJP69467.1 - 0.00017 21.2 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing HHH_5 PF14520.6 EJP69467.1 - 0.013 16.1 0.1 2.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 EJP69467.1 - 0.022 15.4 0.0 0.071 13.7 0.0 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Tma16 PF11176.8 EJP69468.1 - 3.4e-43 147.0 1.0 3.9e-43 146.8 1.0 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Tropomyosin_1 PF12718.7 EJP69468.1 - 0.0093 16.1 1.4 0.021 15.0 1.2 1.6 1 1 0 1 1 1 1 Tropomyosin like DUF932 PF06067.11 EJP69468.1 - 0.092 12.5 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Rhomboid PF01694.22 EJP69469.1 - 3.3e-19 69.4 9.5 3.3e-19 69.4 9.5 1.6 2 0 0 2 2 2 1 Rhomboid family SIR2 PF02146.17 EJP69470.1 - 1.8e-25 89.9 0.0 4.6e-25 88.6 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Organ_specific PF10950.8 EJP69470.1 - 0.011 16.4 0.3 0.05 14.3 0.3 2.1 1 0 0 1 1 1 0 Organ specific protein ATP-synt_G PF04718.15 EJP69471.1 - 2.2e-33 115.0 0.1 3.6e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Collagen_mid PF15984.5 EJP69471.1 - 0.0009 19.0 0.4 0.0013 18.5 0.4 1.2 1 0 0 1 1 1 1 Bacterial collagen, middle region Methyltransf_23 PF13489.6 EJP69472.1 - 1.5e-17 64.0 0.0 3e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EJP69472.1 - 7.9e-07 29.3 0.0 9.5e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EJP69472.1 - 4.3e-06 27.3 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP69472.1 - 0.00039 20.3 0.0 0.0011 18.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EJP69472.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EJP69472.1 - 0.0079 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EJP69472.1 - 0.042 13.2 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EJP69472.1 - 0.047 14.3 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EJP69472.1 - 0.067 12.9 0.0 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EJP69472.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EJP69472.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.12 EJP69472.1 - 0.21 12.3 0.0 0.69 10.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain TFIIA PF03153.13 EJP69473.1 - 3.3e-87 294.2 8.1 4.6e-87 293.7 8.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 EJP69473.1 - 0.24 10.7 6.6 0.35 10.1 6.6 1.2 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.10 EJP69473.1 - 0.98 10.1 9.8 2.9 8.6 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CENP-B_dimeris PF09026.10 EJP69473.1 - 8.4 6.9 16.9 0.91 9.9 9.8 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ANAPC4_WD40 PF12894.7 EJP69474.1 - 6.3e-18 64.9 5.3 6.6e-06 26.3 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJP69474.1 - 1.9e-16 60.1 17.7 0.00033 21.4 0.1 6.5 6 1 1 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EJP69474.1 - 2.5e-06 26.7 0.0 0.00033 19.7 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EJP69474.1 - 3e-06 27.3 0.2 0.0014 18.5 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.6 EJP69475.1 - 7.3e-29 99.5 9.7 1.3e-08 34.7 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EJP69475.1 - 6.3e-24 83.4 3.4 7.6e-05 22.9 0.0 4.9 3 1 2 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EJP69475.1 - 1.4e-22 79.2 1.6 5.6e-06 26.2 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 EJP69475.1 - 5.7e-21 73.8 0.2 0.00022 20.8 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EJP69475.1 - 4.4e-19 68.3 6.0 2.3e-07 30.9 0.1 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EJP69475.1 - 5.5e-19 67.3 2.9 0.001 18.9 0.0 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 EJP69475.1 - 8.8e-08 32.4 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 EJP69476.1 - 2.3e-05 24.6 10.6 0.11 13.0 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EJP69476.1 - 0.00011 22.4 1.9 0.039 14.1 0.1 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EJP69476.1 - 0.0004 21.0 11.7 0.37 11.8 0.8 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP69476.1 - 0.015 15.6 2.2 0.94 9.9 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EJP69476.1 - 0.081 13.4 13.2 0.099 13.1 1.0 3.5 4 0 0 4 4 4 0 Zinc-finger double domain HIG_1_N PF04588.13 EJP69477.1 - 2.7e-05 24.3 1.5 2.7e-05 24.3 1.5 2.6 3 0 0 3 3 3 1 Hypoxia induced protein conserved region Kelch_1 PF01344.25 EJP69478.1 - 1.1e-40 136.9 21.7 8.3e-10 38.1 0.7 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EJP69478.1 - 6.6e-37 124.9 17.7 1.6e-07 31.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EJP69478.1 - 1.8e-34 117.3 11.4 2.5e-07 30.8 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 EJP69478.1 - 3.2e-32 110.3 21.7 2.3e-06 27.5 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EJP69478.1 - 3.3e-32 109.7 16.5 3.4e-06 27.1 0.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EJP69478.1 - 4.2e-31 105.7 17.3 8.9e-09 35.0 0.3 6.5 6 0 0 6 6 6 6 Kelch motif Spt20 PF12090.8 EJP69478.1 - 0.21 11.2 26.1 0.33 10.5 26.1 1.2 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 EJP69478.1 - 5 5.3 22.1 6.6 4.9 22.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dus PF01207.17 EJP69479.1 - 1.2e-39 136.3 0.0 5.9e-28 97.8 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 EJP69479.1 - 0.096 12.8 10.9 0.38 10.9 2.2 2.6 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 EJP69479.1 - 0.66 10.0 7.5 6.8 6.7 0.5 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EJP69479.1 - 7 6.6 16.0 0.43 10.4 6.2 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Peroxin-13_N PF04088.13 EJP69480.1 - 1.9e-49 167.7 0.0 3e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EJP69480.1 - 1.1e-10 41.1 0.0 1.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EJP69480.1 - 2.4e-08 33.5 0.0 4.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP69480.1 - 5.9e-06 26.0 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain LigD_N PF13298.6 EJP69481.1 - 1.2e-35 122.0 0.1 2.1e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Syntaxin-18_N PF10496.9 EJP69482.1 - 3.4e-10 40.0 1.1 3.7e-09 36.7 0.2 2.6 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EJP69482.1 - 0.00092 19.2 0.0 0.0078 16.2 0.0 2.5 3 0 0 3 3 3 1 SNARE domain Aminotran_1_2 PF00155.21 EJP69484.1 - 4.5e-85 286.0 0.0 5.1e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 EJP69485.1 - 1.8e-23 83.0 21.3 3.1e-23 82.3 21.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Totivirus_coat PF05518.11 EJP69486.1 - 2.6 6.0 8.3 3.2 5.7 8.3 1.2 1 0 0 1 1 1 0 Totivirus coat protein NMD3 PF04981.13 EJP69487.1 - 6e-79 264.9 3.4 1e-78 264.2 3.4 1.4 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 EJP69487.1 - 4.2 7.5 10.2 8e+02 0.2 10.2 2.8 1 1 0 1 1 1 0 Double zinc ribbon RRM_1 PF00076.22 EJP69488.1 - 2.7e-05 23.9 0.0 0.0033 17.2 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.11 EJP69488.1 - 0.054 12.9 0.2 0.054 12.9 0.2 1.9 2 0 0 2 2 2 0 AAR2 protein DUF3827 PF12877.7 EJP69488.1 - 0.67 8.3 9.9 0.03 12.7 4.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) CDC45 PF02724.14 EJP69488.1 - 7.5 4.7 10.4 0.31 9.3 3.6 1.8 2 0 0 2 2 2 0 CDC45-like protein Aldedh PF00171.22 EJP69489.1 - 1e-132 443.0 0.0 1.1e-132 442.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EJP69489.1 - 0.00072 18.7 0.2 0.003 16.7 0.2 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EJP69489.1 - 0.054 12.9 0.0 6.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF588 PF04535.12 EJP69490.1 - 0.061 13.1 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF588) GHMP_kinases_N PF00288.26 EJP69492.1 - 4.8e-16 58.8 4.0 4.8e-16 58.8 4.0 2.2 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EJP69492.1 - 1.1e-07 32.1 0.0 1.1e-07 32.1 0.0 1.9 2 1 0 2 2 2 1 GHMP kinases C terminal PPR_2 PF13041.6 EJP69493.1 - 4.7e-45 151.6 12.1 1.6e-08 34.6 0.0 15.1 10 5 8 18 18 18 9 PPR repeat family PPR_3 PF13812.6 EJP69493.1 - 9.2e-32 108.9 0.0 0.0023 18.0 0.0 11.0 8 4 3 12 12 12 8 Pentatricopeptide repeat domain PPR PF01535.20 EJP69493.1 - 2e-25 87.2 25.4 0.00055 20.0 0.0 13.1 17 0 0 17 17 17 5 PPR repeat PPR_1 PF12854.7 EJP69493.1 - 2.6e-23 81.4 1.1 1.4e-07 31.1 0.0 11.4 12 0 0 12 12 12 4 PPR repeat PPR_long PF17177.4 EJP69493.1 - 4.2e-17 62.2 15.2 7.8e-05 22.1 0.0 7.3 3 2 5 8 8 8 6 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EJP69493.1 - 0.027 14.9 0.0 1.7 9.1 0.0 3.6 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 EJP69493.1 - 0.03 14.2 0.8 2.3 8.1 0.1 3.4 2 1 0 3 3 3 0 Mitochondrial ATPase expression DEAD PF00270.29 EJP69494.1 - 1.2e-44 152.2 0.1 1.9e-44 151.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP69494.1 - 5.7e-20 71.7 0.0 2e-19 70.0 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EJP69494.1 - 1.4e-16 60.5 0.1 2.7e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EJP69494.1 - 0.00019 21.5 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Collagen_mid PF15984.5 EJP69495.1 - 0.0064 16.3 4.5 0.0064 16.3 4.5 2.2 1 1 1 2 2 2 2 Bacterial collagen, middle region Chlorosome_CsmC PF11098.8 EJP69495.1 - 0.084 12.9 4.9 0.12 12.3 4.9 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C COPI_assoc PF08507.10 EJP69496.1 - 1.2e-29 103.0 7.4 1.4e-29 102.8 7.4 1.0 1 0 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.9 EJP69496.1 - 2.7 7.4 4.3 0.45 9.9 0.3 1.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF4538 PF15061.6 EJP69496.1 - 7 6.5 10.2 1.5 8.6 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4538) GTP_EFTU PF00009.27 EJP69497.1 - 2e-44 151.4 0.0 3.7e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EJP69497.1 - 8.5e-20 70.6 0.0 1.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EJP69497.1 - 9.9e-14 51.1 0.0 7.4e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EJP69497.1 - 0.0022 18.3 0.1 0.0093 16.3 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 2 DUF3290 PF11694.8 EJP69498.1 - 0.00069 19.6 0.1 0.00086 19.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) Actin PF00022.19 EJP69499.1 - 8.4e-149 495.6 0.0 4e-148 493.4 0.0 1.8 1 1 0 1 1 1 1 Actin GerD PF17898.1 EJP69499.1 - 0.012 15.6 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain Met_gamma_lyase PF06838.11 EJP69499.1 - 0.14 10.7 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase SUN PF03856.13 EJP69501.1 - 6e-73 245.3 12.3 1.2e-72 244.3 12.3 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) PCI PF01399.27 EJP69502.1 - 0.082 13.4 0.0 1.9 9.1 0.0 2.4 2 0 0 2 2 2 0 PCI domain Thiolase_N PF00108.23 EJP69503.1 - 9.5e-87 290.6 0.9 9.5e-87 290.6 0.9 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EJP69503.1 - 1.8e-39 134.2 1.1 1.8e-39 134.2 1.1 1.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EJP69503.1 - 7e-05 22.5 1.7 0.00023 20.8 0.7 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EJP69503.1 - 0.13 12.2 4.0 1.6 8.7 0.0 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 EJP69504.1 - 2.7e-52 176.1 0.1 3.1e-52 176.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP69504.1 - 0.00091 18.9 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EJP69504.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain Myb_DNA-binding PF00249.31 EJP69506.1 - 0.017 15.3 1.8 0.04 14.1 1.8 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain PDZ_1 PF12812.7 EJP69507.1 - 3.7e-56 187.1 0.1 3.4e-36 123.1 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EJP69507.1 - 2.3e-22 80.5 1.7 1.3e-20 74.8 0.3 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 EJP69507.1 - 1.4e-15 56.8 0.1 9.9e-06 25.3 0.1 4.4 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 EJP69507.1 - 2.9e-14 53.2 0.4 8.6e-06 26.0 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 EJP69507.1 - 5.5e-08 33.1 0.1 0.0026 18.1 0.0 4.2 4 0 0 4 4 4 2 PDZ domain Trypsin PF00089.26 EJP69507.1 - 4.5e-05 23.4 0.1 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 EJP69507.1 - 0.00026 20.9 0.8 0.29 11.1 0.1 4.1 4 0 0 4 4 4 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 EJP69507.1 - 0.0088 15.7 0.0 0.03 14.0 0.0 2.0 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S29 PF02907.15 EJP69507.1 - 0.048 13.4 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 EJP69507.1 - 0.27 9.8 0.2 0.68 8.5 0.1 1.6 2 0 0 2 2 2 0 Peptidase S46 Ist1 PF03398.14 EJP69508.1 - 2.1e-60 203.4 4.0 2.6e-60 203.1 4.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Clat_adaptor_s PF01217.20 EJP69509.1 - 1.9e-55 186.7 1.7 2.4e-55 186.4 1.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ArAE_2_N PF10337.9 EJP69510.1 - 1.3e-14 54.1 17.6 3.2e-13 49.6 0.3 3.6 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EJP69510.1 - 8.5e-11 42.1 37.0 1.9e-09 37.7 16.1 2.6 2 1 0 2 2 2 2 Fusaric acid resistance protein-like ALMT PF11744.8 EJP69510.1 - 8e-08 31.5 14.1 8e-08 31.5 14.1 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 EJP69510.1 - 0.006 16.4 0.1 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 TFIID-18kDa PF02269.16 EJP69511.1 - 3.2e-28 97.6 1.1 1.7e-27 95.3 0.2 2.4 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Herpes_ori_bp PF02399.15 EJP69511.1 - 0.064 11.3 0.0 0.081 11.0 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Tim29 PF10171.9 EJP69511.1 - 0.14 11.6 0.0 0.6 9.6 0.0 1.9 2 0 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 LCM PF04072.14 EJP69512.1 - 4.1e-24 85.6 0.0 1.3e-23 84.0 0.0 1.8 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase Hydantoinase_B PF02538.14 EJP69513.1 - 1.9e-213 709.6 0.6 2.4e-213 709.3 0.6 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EJP69513.1 - 4.1e-105 351.2 0.0 8.8e-105 350.1 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EJP69513.1 - 3.6e-58 196.2 0.5 1.4e-56 191.0 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Big_3_5 PF16640.5 EJP69513.1 - 0.11 12.7 0.5 0.78 10.0 0.2 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Fungal_trans PF04082.18 EJP69514.1 - 4.3e-19 68.6 0.2 2.8e-18 65.9 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tcp11 PF05794.13 EJP69514.1 - 0.14 11.2 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 T-complex protein 11 MFS_1 PF07690.16 EJP69515.1 - 2e-32 112.5 25.4 2.7e-32 112.1 25.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Holin_9 PF16936.5 EJP69515.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.7 2 1 0 2 2 2 0 Putative holin Mito_carr PF00153.27 EJP69516.1 - 0.0023 17.8 0.2 0.23 11.4 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Kinesin PF00225.23 EJP69517.1 - 3.4e-114 381.2 0.1 9.7e-114 379.7 0.1 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EJP69517.1 - 1.8e-26 92.9 0.0 7e-26 91.0 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding DnaJ PF00226.31 EJP69518.1 - 1.3e-20 73.3 0.7 2.8e-20 72.2 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain cobW PF02492.19 EJP69519.1 - 1e-43 149.0 0.6 1.6e-43 148.4 0.6 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NOT2_3_5 PF04153.18 EJP69519.1 - 5.4e-25 88.0 2.1 1.2e-24 86.9 2.1 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CUE PF02845.16 EJP69519.1 - 2.5e-08 33.4 0.0 4.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain RsgA_GTPase PF03193.16 EJP69519.1 - 4.7e-05 23.4 0.2 0.32 10.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Septin PF00735.18 EJP69519.1 - 0.0019 17.5 1.6 0.19 11.0 0.3 2.2 2 0 0 2 2 2 2 Septin GTP_EFTU PF00009.27 EJP69519.1 - 0.022 14.3 0.2 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 EJP69519.1 - 0.032 14.7 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJP69519.1 - 0.073 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EJP69519.1 - 0.081 12.6 0.2 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EJP69519.1 - 0.11 11.5 0.1 0.24 10.4 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EJP69519.1 - 0.14 12.5 0.0 0.48 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 EJP69519.1 - 0.19 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 EJP69519.1 - 0.4 10.1 1.9 0.3 10.5 0.2 1.6 2 0 0 2 2 2 0 PhoH-like protein MeaB PF03308.16 EJP69519.1 - 0.52 9.2 6.2 2.3 7.1 0.1 2.9 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mob1_phocein PF03637.17 EJP69520.1 - 1.7e-22 80.3 0.3 2.4e-22 79.7 0.3 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 EJP69520.1 - 0.16 12.2 3.8 0.33 11.3 3.8 1.5 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Zn_clus PF00172.18 EJP69521.1 - 3.6e-07 30.2 8.5 3.6e-07 30.2 8.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP69521.1 - 5.3e-05 22.2 4.5 0.00015 20.7 0.7 2.7 2 1 0 3 3 3 1 Fungal specific transcription factor domain MOSC PF03473.17 EJP69522.1 - 2.1e-24 86.0 0.0 3.3e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EJP69522.1 - 6.5e-10 38.9 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SMC_N PF02463.19 EJP69523.1 - 7.6e-69 231.5 6.2 4.9e-68 228.9 6.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EJP69523.1 - 5.5e-23 81.5 2.8 1.7e-21 76.7 0.2 3.3 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EJP69523.1 - 5.3e-09 36.3 7.8 0.00017 21.5 0.2 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EJP69523.1 - 1.1e-05 26.1 30.4 1.1e-05 26.1 30.4 6.9 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 EJP69523.1 - 0.00012 21.7 0.1 0.0003 20.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tup_N PF08581.10 EJP69523.1 - 0.004 17.4 7.5 0.004 17.4 7.5 8.2 6 2 3 9 9 9 1 Tup N-terminal HIP1_clath_bdg PF16515.5 EJP69523.1 - 0.0043 17.6 6.2 0.0043 17.6 6.2 9.1 3 2 6 9 9 9 1 Clathrin-binding domain of Huntingtin-interacting protein 1 FDX-ACB PF03147.14 EJP69523.1 - 2.2 8.8 10.0 0.59 10.6 1.1 4.1 4 0 0 4 4 4 0 Ferredoxin-fold anticodon binding domain INCENP_ARK-bind PF03941.15 EJP69524.1 - 9.9e-21 73.4 1.1 9.9e-21 73.4 1.1 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region DEAD PF00270.29 EJP69525.1 - 1.2e-41 142.4 0.0 1.7e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP69525.1 - 1e-20 74.1 0.0 7.2e-20 71.4 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EJP69525.1 - 0.00019 20.8 0.0 0.00038 19.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EJP69525.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EJP69525.1 - 0.062 13.6 0.2 0.29 11.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 EJP69526.1 - 2e-15 56.9 13.1 0.0025 18.6 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP69526.1 - 0.0036 17.6 0.1 2.1 8.7 0.0 3.8 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain 2OG-FeII_Oxy_2 PF13532.6 EJP69527.1 - 1.4e-33 116.7 0.0 2e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EJP69527.1 - 2.4e-09 37.1 5.8 4.8e-09 36.2 5.8 1.5 1 0 0 1 1 1 1 GRF zinc finger RibD_C PF01872.17 EJP69528.1 - 1.1e-33 116.7 0.0 1.3e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain LIP PF03583.14 EJP69529.1 - 1.4e-50 172.2 0.0 2e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase PfkB PF00294.24 EJP69531.1 - 3.3e-61 207.2 0.1 3.9e-61 207.0 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF515 PF04415.12 EJP69531.1 - 4.3 5.6 4.3 4 5.7 3.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) UQ_con PF00179.26 EJP69533.1 - 6e-08 32.4 0.2 5.7e-07 29.3 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme BRE PF06113.12 EJP69533.1 - 0.15 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Zn_clus PF00172.18 EJP69534.1 - 3.6e-09 36.6 11.2 6.2e-09 35.8 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ccdc124 PF06244.12 EJP69535.1 - 4e-31 108.3 14.1 6.1e-30 104.4 14.1 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Elf4 PF07011.11 EJP69535.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Early Flowering 4 domain DUF3235 PF11574.8 EJP69535.1 - 0.91 10.4 0.0 0.91 10.4 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) MFS_1 PF07690.16 EJP69536.1 - 9.2e-39 133.4 11.2 9.2e-39 133.4 11.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP69536.1 - 2.4e-09 36.6 1.6 2.4e-09 36.6 1.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EJP69536.1 - 0.013 14.3 16.1 0.04 12.8 3.3 2.7 1 1 2 3 3 3 0 MFS_1 like family Fungal_trans PF04082.18 EJP69537.1 - 3.5e-31 108.2 0.0 5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69537.1 - 2.1e-08 34.1 10.4 3.5e-08 33.4 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NicO PF03824.16 EJP69538.1 - 0.059 12.7 0.2 0.079 12.3 0.2 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein IHO1 PF15771.5 EJP69538.1 - 0.55 8.9 4.6 0.68 8.6 4.6 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Dioxygenase_C PF00775.21 EJP69539.1 - 1.8e-36 125.3 0.0 3e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EJP69539.1 - 7.8e-26 89.7 0.1 1.4e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EJP69539.1 - 0.01 16.1 0.0 0.043 14.1 0.0 2.0 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DAO PF01266.24 EJP69541.1 - 8.5e-61 206.5 9.0 1.4e-60 205.8 9.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJP69541.1 - 0.00031 20.1 0.2 0.054 12.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP69541.1 - 0.0013 18.9 1.0 0.0042 17.3 1.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SlyX PF04102.12 EJP69541.1 - 0.0025 18.4 5.1 0.71 10.5 0.3 2.6 2 0 0 2 2 2 2 SlyX Thi4 PF01946.17 EJP69541.1 - 0.0083 15.4 0.3 0.022 14.0 0.3 1.6 1 0 0 1 1 1 1 Thi4 family SKA2 PF16740.5 EJP69541.1 - 0.037 13.8 2.6 1.6 8.6 0.5 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF2046 PF09755.9 EJP69541.1 - 0.048 12.9 1.0 0.24 10.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) NAD_binding_9 PF13454.6 EJP69541.1 - 0.11 12.5 0.8 1.4 8.9 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EJP69541.1 - 0.11 13.1 0.1 0.27 11.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EJP69541.1 - 0.11 11.0 0.4 1 7.8 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) TMCO5 PF14992.6 EJP69541.1 - 0.25 10.9 1.1 0.41 10.2 1.1 1.4 1 1 0 1 1 1 0 TMCO5 family DUF2188 PF09954.9 EJP69541.1 - 0.47 10.6 3.0 24 5.2 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) Mitofilin PF09731.9 EJP69541.1 - 1.1 8.0 6.4 1.9 7.3 6.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2415 PF10313.9 EJP69542.1 - 6.4e-12 45.2 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 EJP69542.1 - 0.00098 19.4 0.0 4 7.8 0.0 3.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 EJP69543.1 - 1.6e-265 882.0 14.3 1.9e-265 881.7 14.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJP69543.1 - 1.3e-13 50.4 3.6 1.5e-11 43.7 0.8 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EJP69543.1 - 0.00085 19.1 0.1 0.0027 17.5 0.1 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EJP69543.1 - 0.015 14.6 1.2 0.29 10.3 0.0 2.8 2 1 1 3 3 3 0 StbA protein Big_3_4 PF13754.6 EJP69543.1 - 0.066 12.9 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function SMBP PF16785.5 EJP69543.1 - 0.91 9.8 6.9 0.44 10.8 4.1 2.0 2 0 0 2 2 2 0 Small metal-binding protein SRP68 PF16969.5 EJP69545.1 - 6.9e-203 675.7 2.4 7.8e-203 675.5 2.4 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Mis14 PF08641.12 EJP69545.1 - 0.0046 17.3 1.2 0.0072 16.6 0.0 1.8 2 0 0 2 2 2 1 Kinetochore protein Mis14 like PhnG PF06754.12 EJP69545.1 - 0.057 13.4 1.9 0.16 11.9 1.5 1.9 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG PMEI PF04043.15 EJP69545.1 - 3.6 7.9 5.7 3.3 8.0 0.4 2.8 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor SNF2_N PF00176.23 EJP69546.1 - 4e-72 242.9 0.1 1.2e-71 241.3 0.0 1.8 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP69546.1 - 2.9e-13 50.1 0.0 1.1e-12 48.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP69546.1 - 1.4e-06 28.2 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 EJP69546.1 - 4.4e-05 23.4 3.4 8.4e-05 22.5 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EJP69546.1 - 0.00046 20.2 0.0 0.0028 17.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 EJP69546.1 - 0.0048 16.9 0.7 0.011 15.7 0.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EJP69546.1 - 0.044 13.6 4.5 0.027 14.3 1.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJP69546.1 - 0.097 12.5 0.2 0.097 12.5 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJP69546.1 - 0.3 11.5 3.4 0.69 10.3 3.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EJP69546.1 - 1 9.3 7.5 0.088 12.7 2.3 1.9 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJP69546.1 - 2.1 8.3 6.4 6.1 6.8 6.4 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 GCP_N_terminal PF17681.1 EJP69547.1 - 1.4e-62 212.1 0.0 2.7e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EJP69547.1 - 1.5e-60 205.3 2.3 1.5e-60 205.3 2.3 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal CLZ PF16526.5 EJP69547.1 - 0.82 10.1 2.7 1.1 9.7 0.7 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Proteasome PF00227.26 EJP69548.1 - 8.6e-55 185.2 0.2 1.1e-54 184.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJP69548.1 - 5e-11 42.1 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 EJP69549.1 - 7.5e-25 87.5 0.0 2.5e-13 49.6 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69549.1 - 4.8e-08 33.0 10.2 8.9e-08 32.1 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP69549.1 - 4.5e-05 22.6 0.2 7.7e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ntox21 PF15526.6 EJP69549.1 - 0.0024 18.1 0.1 0.006 16.9 0.1 1.7 1 0 0 1 1 1 1 Novel toxin 21 Ldl_recept_a PF00057.18 EJP69549.1 - 1.5 9.1 4.4 3.1 8.1 4.4 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A p450 PF00067.22 EJP69550.1 - 2e-61 208.2 0.0 2.7e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Frag1 PF10277.9 EJP69551.1 - 1.5e-40 139.1 8.4 1.5e-40 139.1 8.4 2.5 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 EJP69551.1 - 0.025 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.11 EJP69552.1 - 2.6e-26 91.5 0.3 2e-25 88.6 0.2 2.3 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EJP69552.1 - 0.0062 17.3 6.5 0.21 12.5 0.2 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat DUF1744 PF08490.12 EJP69553.1 - 1.8e-153 510.9 0.0 2.8e-153 510.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EJP69553.1 - 1.5e-76 257.7 0.2 2.3e-76 257.1 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EJP69553.1 - 4e-15 55.5 0.1 1.2e-12 47.3 0.2 3.1 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EJP69553.1 - 4.4e-08 33.1 0.2 1.3e-07 31.5 0.2 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EJP69553.1 - 2.9e-06 27.4 0.1 5.3e-05 23.3 0.0 2.8 2 1 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.8 EJP69554.1 - 2e-35 120.6 1.0 2e-35 120.6 1.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) SARAF PF06682.12 EJP69554.1 - 0.0062 16.2 0.1 0.013 15.2 0.1 1.5 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CCB1 PF12046.8 EJP69554.1 - 0.064 12.6 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B Aldose_epim PF01263.20 EJP69556.1 - 3e-57 194.2 0.0 3.9e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2981 PF11200.8 EJP69557.1 - 5.7 6.6 7.0 11 5.7 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Gpi1 PF05024.15 EJP69558.1 - 5.8e-77 258.0 6.5 1.2e-76 256.9 6.5 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.12 EJP69558.1 - 3.7e-25 88.0 3.6 7.1e-25 87.0 3.6 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) 7tm_1 PF00001.21 EJP69558.1 - 0.014 14.7 0.4 0.052 12.9 0.1 2.0 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) COX17 PF05051.13 EJP69558.1 - 0.021 15.2 0.6 0.044 14.1 0.6 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EJP69558.1 - 0.046 13.7 2.7 0.091 12.8 0.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TBCC PF07986.12 EJP69559.1 - 4e-28 97.6 0.0 6.3e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EJP69559.1 - 1.4e-07 32.0 0.1 2.4e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain F_actin_bind PF08919.10 EJP69559.1 - 0.01 15.9 0.1 1.3 9.1 0.1 2.3 1 1 1 2 2 2 0 F-actin binding FNIP_M PF14637.6 EJP69559.1 - 0.056 13.4 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain DUF5082 PF16888.5 EJP69559.1 - 0.068 13.5 0.8 0.24 11.7 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Mucin-like PF16058.5 EJP69559.1 - 0.23 11.5 1.2 0.42 10.7 1.2 1.3 1 0 0 1 1 1 0 Mucin-like NPV_P10 PF05531.12 EJP69559.1 - 0.45 11.0 2.0 1.8 9.1 0.7 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.13 EJP69560.1 - 5.9e-17 61.5 0.0 2.4e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF4140 PF13600.6 EJP69560.1 - 0.032 14.7 1.3 0.16 12.4 1.3 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CODH_A_N PF18537.1 EJP69560.1 - 0.038 14.0 0.4 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Spc29 PF17082.5 EJP69560.1 - 0.06 13.2 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 DPM3 PF08285.11 EJP69560.1 - 0.24 11.6 0.5 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) iPGM_N PF06415.13 EJP69561.1 - 6.7e-75 251.2 0.0 9.2e-75 250.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EJP69561.1 - 3e-67 226.6 0.0 3.5e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EJP69561.1 - 0.0001 22.0 0.0 0.00036 20.3 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EJP69561.1 - 0.00011 21.8 0.0 0.00044 19.7 0.0 2.0 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.24 EJP69561.1 - 0.024 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Toprim_N PF08275.11 EJP69562.1 - 0.02 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain FRQ PF09421.10 EJP69563.1 - 0 1281.0 43.8 0 1280.6 43.8 1.0 1 0 0 1 1 1 1 Frequency clock protein Prenylcys_lyase PF07156.14 EJP69564.1 - 4.2e-83 279.4 0.0 5.7e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EJP69564.1 - 5.5e-11 42.5 0.1 1.4e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EJP69564.1 - 1.4e-08 34.5 0.0 8.6e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 EJP69564.1 - 3.3e-07 30.2 0.2 6.6e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EJP69564.1 - 9.9e-05 22.4 0.1 0.00035 20.6 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 EJP69564.1 - 0.0018 17.2 0.0 0.18 10.5 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox_2 PF07992.14 EJP69564.1 - 0.0028 16.9 0.1 0.0065 15.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP69564.1 - 0.031 13.5 0.0 0.074 12.3 0.0 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EJP69564.1 - 0.072 11.8 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EJP69564.1 - 0.16 12.5 0.0 13 6.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase VID27 PF08553.10 EJP69565.1 - 1e-191 636.6 0.6 1.3e-191 636.2 0.6 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EJP69565.1 - 6.4e-76 254.0 0.2 6.4e-76 254.0 0.2 3.2 3 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 EJP69565.1 - 7.7e-41 138.8 0.2 2.2e-40 137.3 0.1 1.8 2 0 0 2 2 2 1 VID27 PH-like domain Nop14 PF04147.12 EJP69565.1 - 2.1 6.5 11.6 3.7 5.7 11.6 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EJP69565.1 - 9.6 4.4 8.3 15 3.7 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein HET PF06985.11 EJP69566.1 - 1.2e-19 71.1 0.0 3.7e-19 69.5 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_transf_20 PF00982.21 EJP69567.1 - 2.9e-196 652.7 0.0 3.4e-196 652.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EJP69567.1 - 0.062 13.0 0.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain DNA_pol_A_exo1 PF01612.20 EJP69568.1 - 1.7e-39 135.4 0.2 2.4e-39 134.8 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EJP69568.1 - 2.4e-27 95.4 0.5 7.7e-27 93.8 0.5 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 EJP69568.1 - 1e-10 41.4 0.0 2.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain YL1 PF05764.13 EJP69568.1 - 0.046 13.8 18.5 0.088 12.9 18.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DRY_EERY PF09750.9 EJP69568.1 - 0.11 12.8 4.8 0.23 11.7 4.8 1.6 1 0 0 1 1 1 0 Alternative splicing regulator CDC45 PF02724.14 EJP69568.1 - 0.73 8.1 15.9 1.4 7.1 15.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.10 EJP69568.1 - 4.2 7.4 6.4 7.8 6.5 6.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ATP-synt_C PF00137.21 EJP69569.1 - 1.5e-10 41.2 13.2 1.5e-10 41.2 13.2 1.6 2 0 0 2 2 2 1 ATP synthase subunit C DnaJ PF00226.31 EJP69570.1 - 5.3e-06 26.5 0.1 2.3e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 DnaJ domain DUF3759 PF12585.8 EJP69571.1 - 0.44 10.6 5.1 0.26 11.3 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3759) YtxH PF12732.7 EJP69572.1 - 1.8 9.1 11.8 1.7e+02 2.8 11.8 2.5 1 1 0 1 1 1 0 YtxH-like protein Alanine_zipper PF11839.8 EJP69572.1 - 3.3 8.1 13.9 2.8 8.4 12.0 1.9 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein CsbD PF05532.12 EJP69572.1 - 4.6 7.2 20.0 32 4.5 15.9 2.9 2 1 0 2 2 2 0 CsbD-like GatB_N PF02934.15 EJP69573.1 - 1.7e-96 322.8 0.0 2.3e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EJP69573.1 - 3.4e-08 33.5 0.0 1e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 GatB domain FerA PF08165.11 EJP69574.1 - 0.0032 17.4 0.1 0.0072 16.2 0.1 1.5 1 0 0 1 1 1 1 FerA (NUC095) domain CC2-LZ PF16516.5 EJP69574.1 - 1.6 9.1 3.9 5.7 7.4 3.9 1.8 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Clathrin PF00637.20 EJP69576.1 - 7.9e-21 74.4 0.5 5.9e-20 71.6 0.2 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.9 EJP69576.1 - 0.00027 21.2 0.2 0.0092 16.3 0.3 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.6 EJP69576.1 - 0.034 14.2 2.1 9 6.6 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RXT2_N PF08595.11 EJP69576.1 - 0.48 10.4 16.6 0.031 14.3 10.7 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal zf-RING_2 PF13639.6 EJP69576.1 - 0.56 10.6 1.5 1.3 9.5 0.2 2.1 2 0 0 2 2 2 0 Ring finger domain NOA36 PF06524.12 EJP69576.1 - 6.2 6.0 25.9 14 4.9 25.9 1.6 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 EJP69576.1 - 8.8 5.6 8.8 25 4.2 8.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 EJP69576.1 - 9.2 4.2 28.1 15 3.5 28.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi ANAPC1 PF12859.7 EJP69577.1 - 5.7e-37 127.2 0.4 5.7e-37 127.2 0.4 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EJP69577.1 - 0.0018 18.6 0.2 3.9 8.1 0.1 4.2 4 0 0 4 4 4 2 Proteasome/cyclosome repeat eIF3_N PF09440.10 EJP69578.1 - 3.5e-45 153.7 0.4 7e-45 152.7 0.4 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EJP69578.1 - 2.8e-12 47.1 0.0 7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain Img2 PF05046.14 EJP69579.1 - 4e-21 75.1 0.0 5.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 EJP69579.1 - 0.022 15.3 0.0 0.033 14.7 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor SUI1 ARID PF01388.21 EJP69580.1 - 1.6e-17 63.9 0.0 1.6e-17 63.9 0.0 2.7 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain HicA_toxin PF07927.12 EJP69582.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, ABC_membrane_2 PF06472.15 EJP69583.1 - 1.4e-90 303.3 1.0 3.1e-90 302.2 0.1 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EJP69583.1 - 5.6e-16 59.3 0.0 1.4e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 EJP69583.1 - 0.0085 16.6 0.4 0.59 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EJP69583.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EJP69583.1 - 0.014 15.7 1.0 0.023 15.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EJP69583.1 - 0.018 15.5 0.0 0.051 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EJP69583.1 - 0.025 14.3 0.0 0.082 12.6 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EJP69583.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EJP69583.1 - 0.061 12.8 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EJP69583.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NIF PF03031.18 EJP69584.1 - 6.8e-54 181.9 0.1 9.5e-54 181.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.16 EJP69584.1 - 2.7e-18 65.7 1.9 5e-18 64.9 1.9 1.5 1 0 0 1 1 1 1 Sec61beta family Glyco_transf_28 PF03033.20 EJP69585.1 - 9.6e-20 71.0 0.2 1.3e-11 44.6 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EJP69585.1 - 3.7e-06 26.0 0.0 6.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 EJP69585.1 - 9.5e-06 25.9 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 EJP69585.1 - 0.078 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Serglycin PF04360.12 EJP69585.1 - 0.12 12.3 8.2 0.29 11.1 8.2 1.6 1 0 0 1 1 1 0 Serglycin RAP80_UIM PF18282.1 EJP69585.1 - 2.2 8.1 10.0 4.8 7.0 0.3 3.0 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif zinc_ribbon_15 PF17032.5 EJP69586.1 - 0.00016 22.4 0.1 0.00023 21.8 0.1 1.3 1 0 0 1 1 1 1 zinc-ribbon family Pro-rich PF15240.6 EJP69586.1 - 0.093 13.0 45.6 0.12 12.7 45.6 1.1 1 0 0 1 1 1 0 Proline-rich RNase_P_p30 PF01876.16 EJP69587.1 - 1.1e-57 195.0 0.0 1.9e-57 194.2 0.0 1.4 2 0 0 2 2 2 1 RNase P subunit p30 DUF1295 PF06966.12 EJP69589.1 - 7.6e-56 189.3 1.2 9.4e-56 189.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EJP69589.1 - 1.6e-05 24.9 2.5 0.00012 22.1 0.0 2.9 1 1 2 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EJP69589.1 - 9e-05 22.8 0.1 0.00036 20.9 0.0 2.2 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EJP69589.1 - 0.00064 20.1 0.1 0.0028 18.0 0.0 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EJP69589.1 - 0.0032 16.3 0.3 0.0071 15.2 0.1 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Chi-conotoxin PF16981.5 EJP69589.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily PIG-P PF08510.12 EJP69589.1 - 0.092 12.7 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 PIG-P GFA PF04828.14 EJP69590.1 - 0.00066 20.0 0.9 0.00066 20.0 0.9 2.2 2 1 1 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme HCV_NS5a_1a PF08300.13 EJP69590.1 - 4.3 7.5 7.7 2.5 8.3 4.0 2.3 2 1 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain Med8 PF10232.9 EJP69591.1 - 6.2e-41 140.5 9.9 1.1e-40 139.6 9.9 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 CENP-B_dimeris PF09026.10 EJP69591.1 - 0.047 14.1 16.2 0.099 13.0 16.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SGT1 PF07093.11 EJP69591.1 - 0.079 11.4 1.6 0.092 11.2 1.6 1.2 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 EJP69591.1 - 0.085 11.1 11.2 0.11 10.7 11.2 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EJP69591.1 - 0.18 11.1 6.7 0.22 10.8 6.7 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 EJP69591.1 - 0.19 11.4 10.8 0.3 10.8 10.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 EJP69591.1 - 0.29 10.8 6.4 0.56 9.9 6.4 1.5 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 EJP69591.1 - 0.32 10.6 7.4 0.4 10.2 7.4 1.2 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.13 EJP69591.1 - 0.42 10.5 12.1 1.3 8.8 11.8 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.8 EJP69591.1 - 0.48 10.6 14.4 0.66 10.2 14.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 EJP69591.1 - 0.62 10.1 7.7 1.4 9.0 7.7 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 EJP69591.1 - 0.67 9.3 12.8 0.86 9.0 12.8 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EJP69591.1 - 0.88 8.6 19.0 1.2 8.2 19.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 EJP69591.1 - 0.95 7.7 10.1 1.3 7.2 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EJP69591.1 - 1.2 8.3 17.1 1.7 7.9 17.1 1.1 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 EJP69591.1 - 1.6 8.5 6.0 2.4 7.9 6.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Pes-10 PF07149.11 EJP69591.1 - 2.2 7.2 12.0 2.2 7.3 11.0 1.4 2 0 0 2 2 2 0 Pes-10 Sporozoite_P67 PF05642.11 EJP69591.1 - 4.3 5.3 7.3 5.7 4.9 7.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4637 PF15470.6 EJP69591.1 - 5.6 6.7 10.1 11 5.7 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) GCIP PF13324.6 EJP69591.1 - 8.5 5.9 8.9 1.6 8.3 4.7 1.9 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting Sulfatase PF00884.23 EJP69592.1 - 5.8e-57 193.4 0.1 7.5e-57 193.1 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EJP69592.1 - 2.4e-25 88.1 1.1 5e-25 87.1 0.2 2.1 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EJP69592.1 - 2.8e-10 40.3 1.1 8e-09 35.5 0.3 2.5 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EJP69592.1 - 1e-05 24.4 0.0 1.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 EJP69592.1 - 0.013 15.8 0.8 0.019 15.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) DUF1501 PF07394.12 EJP69592.1 - 0.026 13.6 0.1 0.044 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4994 PF16385.5 EJP69592.1 - 0.047 13.6 0.1 1.2 9.1 0.1 2.4 1 1 0 1 1 1 0 Domain of unknown function Ribosomal_L27e PF01777.18 EJP69592.1 - 0.051 13.9 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L27e protein family RasGAP_C PF03836.15 EJP69593.1 - 2.7e-49 166.9 5.0 1e-48 165.0 5.0 2.1 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.19 EJP69593.1 - 2.9e-47 161.1 0.0 6.7e-47 159.9 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 EJP69593.1 - 3.3e-14 51.3 41.5 0.0089 15.7 1.4 12.9 13 0 0 13 13 13 6 IQ calmodulin-binding motif CH PF00307.31 EJP69593.1 - 5.1e-11 42.7 0.1 3e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF4936 PF16290.5 EJP69593.1 - 1.8 9.3 4.3 22 5.8 0.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) DUF155 PF02582.14 EJP69594.1 - 1.2e-53 181.8 0.0 2.2e-53 180.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 EJP69594.1 - 0.21 11.4 0.9 0.46 10.3 0.9 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator TPT PF03151.16 EJP69595.1 - 8.4e-33 113.9 14.5 1e-32 113.7 14.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EJP69595.1 - 4e-08 32.8 19.0 5.4e-08 32.4 19.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EJP69595.1 - 2e-05 24.8 31.9 0.00025 21.2 9.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3074 PF11274.8 EJP69597.1 - 1.4e-40 139.3 0.2 1.4e-40 139.3 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) DivIVA PF05103.13 EJP69597.1 - 6.2 6.9 7.0 0.41 10.7 1.3 1.9 2 0 0 2 2 2 0 DivIVA protein TAFII55_N PF04658.13 EJP69598.1 - 1.1e-51 174.8 0.1 1.1e-51 174.8 0.1 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region FlxA PF14282.6 EJP69598.1 - 0.063 13.3 2.1 0.22 11.5 2.1 2.0 1 0 0 1 1 1 0 FlxA-like protein Atg14 PF10186.9 EJP69598.1 - 0.094 11.8 1.3 0.17 10.9 1.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SDA1 PF05285.12 EJP69598.1 - 1.1 8.6 28.7 0.053 12.9 22.4 1.8 2 0 0 2 2 2 0 SDA1 RXT2_N PF08595.11 EJP69598.1 - 8.8 6.3 20.1 2.2 8.3 7.9 3.2 3 0 0 3 3 3 0 RXT2-like, N-terminal Kinesin PF00225.23 EJP69600.1 - 5.1e-95 318.2 0.1 5.1e-95 318.2 0.1 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EJP69600.1 - 3.3e-21 75.8 0.0 7.5e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PKcGMP_CC PF16808.5 EJP69600.1 - 0.093 12.6 7.9 0.058 13.3 0.4 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Stk19 PF10494.9 EJP69601.1 - 1.3e-60 205.1 0.0 1.6e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Sulfate_transp PF00916.20 EJP69602.1 - 3.1e-56 190.8 14.4 4.5e-56 190.2 14.4 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EJP69602.1 - 1.5e-14 53.8 0.0 4.2e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain STAS PF01740.21 EJP69602.1 - 3e-09 36.5 0.0 7.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.11 EJP69603.1 - 6.3e-12 45.9 0.0 9e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 EJP69603.1 - 0.07 13.9 0.0 0.57 11.0 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliT EF1_GNE PF00736.19 EJP69604.1 - 9.3e-34 115.5 1.8 1.4e-33 114.9 1.8 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EJP69604.1 - 3.9e-15 56.0 6.6 3.9e-15 56.0 6.6 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 EJP69604.1 - 0.00028 21.0 0.3 0.0024 18.0 0.1 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP69604.1 - 0.00037 20.6 0.1 0.0014 18.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Proteasom_Rpn13 PF04683.13 EJP69605.1 - 1.1e-24 86.8 0.0 1.7e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EJP69605.1 - 1.8e-10 41.0 0.6 4e-09 36.6 0.6 2.2 1 1 0 1 1 1 1 UCH-binding domain RRM_1 PF00076.22 EJP69606.1 - 9.7e-14 51.0 0.0 3.5e-05 23.6 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP69606.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RRM_3 PF08777.11 EJP69606.1 - 0.025 14.6 1.4 0.86 9.7 0.0 3.3 4 0 0 4 4 4 0 RNA binding motif DUF3405 PF11885.8 EJP69607.1 - 3.5e-224 745.2 0.2 4.2e-224 744.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.24 EJP69608.1 - 3.7e-45 154.1 0.0 4.3e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arf PF00025.21 EJP69609.1 - 1.8e-79 265.2 0.2 2.1e-79 265.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EJP69609.1 - 1.7e-14 54.0 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EJP69609.1 - 2.2e-14 53.3 0.0 2.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EJP69609.1 - 2.7e-13 49.8 1.5 2e-09 37.1 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EJP69609.1 - 3.3e-13 49.5 0.0 3.7e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EJP69609.1 - 1.7e-10 40.6 0.0 2.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJP69609.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EJP69609.1 - 0.0099 15.2 1.0 0.029 13.7 1.0 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_2 PF07724.14 EJP69610.1 - 1.2e-43 149.2 0.0 1.2e-42 146.0 0.0 2.5 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EJP69610.1 - 4e-36 123.1 3.1 4e-36 123.1 3.1 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EJP69610.1 - 8.9e-25 86.6 0.2 3e-24 84.9 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EJP69610.1 - 9.5e-19 68.1 0.0 7.3e-10 39.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EJP69610.1 - 1.6e-12 47.6 0.2 1.9e-08 34.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EJP69610.1 - 5.1e-10 40.0 3.4 0.00095 19.6 0.0 4.2 2 2 2 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 EJP69610.1 - 1.2e-06 28.3 0.5 0.00049 19.8 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 EJP69610.1 - 1.4e-05 24.5 0.1 0.0032 16.9 0.1 3.5 3 1 0 3 3 2 1 Bacterial TniB protein AAA_22 PF13401.6 EJP69610.1 - 1.6e-05 25.2 7.1 0.041 14.2 0.1 4.1 3 2 0 3 3 3 2 AAA domain NACHT PF05729.12 EJP69610.1 - 9.7e-05 22.3 0.1 0.52 10.2 0.1 2.7 2 1 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 EJP69610.1 - 0.00011 21.8 0.0 0.58 9.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 EJP69610.1 - 0.00013 22.0 0.4 0.65 10.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 EJP69610.1 - 0.00024 21.1 9.1 0.31 10.9 0.1 4.1 3 3 2 5 5 3 2 ATPase domain predominantly from Archaea ERM PF00769.19 EJP69610.1 - 0.0012 18.7 7.7 0.0022 17.9 7.7 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_18 PF13238.6 EJP69610.1 - 0.0013 19.3 0.8 0.29 11.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EJP69610.1 - 0.0013 18.5 0.3 1.7 8.4 0.0 2.7 2 1 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 EJP69610.1 - 0.0023 18.5 1.9 0.28 11.7 0.0 3.3 3 0 0 3 3 3 1 ABC transporter CENP-F_leu_zip PF10473.9 EJP69610.1 - 0.0025 17.9 12.9 0.0064 16.5 12.9 1.7 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UvrD-helicase PF00580.21 EJP69610.1 - 0.0031 17.1 1.8 0.2 11.1 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_24 PF13479.6 EJP69610.1 - 0.0049 16.6 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EJP69610.1 - 0.0075 16.6 0.0 1.2 9.5 0.0 2.9 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 EJP69610.1 - 0.0096 15.3 0.1 2.5 7.4 0.0 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 EJP69610.1 - 0.014 15.0 0.0 0.66 9.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EJP69610.1 - 0.015 15.2 1.3 1.7 8.5 0.0 2.9 3 0 0 3 3 2 0 RsgA GTPase AAA_28 PF13521.6 EJP69610.1 - 0.015 15.6 0.5 9.2 6.5 0.0 3.4 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 EJP69610.1 - 0.015 15.3 0.3 8 6.5 0.0 3.0 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EJP69610.1 - 0.017 14.8 0.0 0.58 9.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EJP69610.1 - 0.02 15.1 0.1 3.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EJP69610.1 - 0.041 13.0 1.0 0.81 8.8 0.4 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 EJP69610.1 - 0.042 13.6 0.0 0.98 9.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 EJP69610.1 - 0.057 13.4 2.9 10 6.1 0.0 3.6 3 1 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EJP69610.1 - 0.058 13.6 0.0 19 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DNA_topoisoIV PF00521.20 EJP69610.1 - 0.061 12.2 2.5 0.095 11.6 2.5 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A PhoH PF02562.16 EJP69610.1 - 0.062 12.8 0.1 1.6 8.1 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 EJP69610.1 - 0.077 12.3 0.4 2.4 7.4 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin DUF4407 PF14362.6 EJP69610.1 - 0.092 12.1 1.2 0.15 11.4 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1154 PF06631.11 EJP69610.1 - 0.11 12.5 2.9 1.7 8.7 2.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1154) DUF1640 PF07798.11 EJP69610.1 - 0.12 12.4 6.5 0.26 11.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_19 PF13245.6 EJP69610.1 - 0.14 12.5 2.3 0.99 9.7 0.0 3.1 3 1 1 4 4 3 0 AAA domain OEP PF02321.18 EJP69610.1 - 0.16 11.8 3.7 0.33 10.8 3.7 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein Cob_adeno_trans PF01923.18 EJP69610.1 - 0.34 11.0 2.8 0.93 9.6 2.8 1.7 1 0 0 1 1 1 0 Cobalamin adenosyltransferase UPF0242 PF06785.11 EJP69610.1 - 0.4 10.8 7.8 0.84 9.7 7.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3782 PF12644.7 EJP69610.1 - 0.61 10.3 5.1 1.6 9.0 3.7 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3782) Atg14 PF10186.9 EJP69610.1 - 0.64 9.0 5.5 1.1 8.3 5.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CR6_interact PF10147.9 EJP69610.1 - 1.2 8.9 10.0 2.2 7.9 10.0 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 FAM76 PF16046.5 EJP69610.1 - 2.3 7.5 5.3 3.7 6.8 5.3 1.2 1 0 0 1 1 1 0 FAM76 protein GrpE PF01025.19 EJP69610.1 - 3.6 7.2 9.9 9.3 5.9 9.9 1.6 1 0 0 1 1 1 0 GrpE FapA PF03961.13 EJP69610.1 - 3.8 6.0 8.5 7.3 5.1 8.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 EJP69610.1 - 4.5 7.5 15.8 0.89 9.8 11.1 2.4 3 0 0 3 3 1 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.6 EJP69610.1 - 5.9 7.3 21.6 3e+02 1.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain DUF4061 PF13270.6 EJP69610.1 - 7.3 7.0 7.6 3.3 8.1 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DUF4337 PF14235.6 EJP69610.1 - 7.7 6.6 5.4 14 5.8 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) APG6_N PF17675.1 EJP69610.1 - 9.2 6.8 16.2 24 5.4 16.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_L6e PF01159.19 EJP69611.1 - 2.1e-38 131.3 0.2 2.1e-38 131.3 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Peptidase_M49 PF03571.15 EJP69612.1 - 4e-241 801.2 0.0 4.8e-241 800.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Glucosamine_iso PF01182.20 EJP69612.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AAA_33 PF13671.6 EJP69613.1 - 1.6e-12 47.8 0.0 2.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 EJP69613.1 - 2.5e-11 44.0 0.0 3.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EJP69613.1 - 1.2e-09 38.8 0.0 3.8e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EJP69613.1 - 1.5e-05 25.5 0.0 3.9e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EJP69613.1 - 4.2e-05 23.9 0.1 6.7e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EJP69613.1 - 7.3e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 EJP69613.1 - 0.00012 22.6 0.0 0.00017 22.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJP69613.1 - 0.00033 21.1 0.0 0.00069 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EJP69613.1 - 0.00044 20.2 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain dNK PF01712.19 EJP69613.1 - 0.0011 18.9 0.0 1 9.2 0.0 2.4 2 1 0 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 EJP69613.1 - 0.0038 17.5 0.0 0.0063 16.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EJP69613.1 - 0.0041 17.1 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 EJP69613.1 - 0.0051 16.8 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Thymidylate_kin PF02223.17 EJP69613.1 - 0.0059 16.3 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase Ploopntkinase1 PF18748.1 EJP69613.1 - 0.0059 16.2 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 ATPase_2 PF01637.18 EJP69613.1 - 0.0083 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EJP69613.1 - 0.0095 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EJP69613.1 - 0.0098 15.9 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP69613.1 - 0.0099 16.2 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EJP69613.1 - 0.01 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 EJP69613.1 - 0.012 15.7 0.0 0.1 12.7 0.0 2.3 1 1 0 1 1 1 0 Cytidylate kinase-like family Parvo_NS1 PF01057.17 EJP69613.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 EJP69613.1 - 0.018 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.18 EJP69613.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 EJP69613.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.6 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.20 EJP69613.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.3 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_23 PF13476.6 EJP69613.1 - 0.035 14.6 0.0 0.057 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EJP69613.1 - 0.037 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EJP69613.1 - 0.043 13.5 0.0 0.084 12.6 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EJP69613.1 - 0.047 14.1 0.0 0.075 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EJP69613.1 - 0.048 14.2 0.0 0.086 13.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter CoaE PF01121.20 EJP69613.1 - 0.051 13.3 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase PhoH PF02562.16 EJP69613.1 - 0.059 12.8 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 EJP69613.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EJP69613.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 EJP69613.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 EJP69613.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EJP69613.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region 2-oxoacid_dh PF00198.23 EJP69614.1 - 1.6e-75 253.5 0.2 2.1e-75 253.1 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EJP69614.1 - 6.5e-18 64.3 0.1 1.4e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EJP69614.1 - 1.3e-13 51.1 0.3 3e-13 49.8 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain ATP-synt_10 PF05176.14 EJP69615.1 - 7.6e-74 248.2 0.0 9.9e-74 247.8 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein TetR_C_31 PF17940.1 EJP69615.1 - 0.08 13.2 0.3 0.42 10.8 0.1 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain V-SNARE_C PF12352.8 EJP69616.1 - 1e-12 48.1 6.3 1.1e-12 48.1 0.1 2.8 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF5082 PF16888.5 EJP69616.1 - 0.027 14.8 3.1 0.6 10.4 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 EJP69616.1 - 0.11 11.6 5.3 0.13 11.3 5.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EJP69616.1 - 0.13 11.1 10.2 0.041 12.8 7.6 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Not3 PF04065.15 EJP69616.1 - 0.26 10.7 3.8 1.7 8.1 2.0 2.0 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Peptidase_M3_N PF08439.10 EJP69616.1 - 1.2 9.5 4.8 23 5.3 0.1 3.7 3 1 2 5 5 5 0 Oligopeptidase F Snapin_Pallidin PF14712.6 EJP69616.1 - 2.7 8.5 8.1 0.67 10.4 4.2 2.0 3 0 0 3 3 3 0 Snapin/Pallidin FliJ PF02050.16 EJP69616.1 - 3.4 7.9 9.6 0.35 11.1 4.2 2.1 3 0 0 3 3 3 0 Flagellar FliJ protein Ribosomal_L29 PF00831.23 EJP69617.1 - 2.2e-17 62.8 0.2 2.2e-17 62.8 0.2 2.4 2 2 0 2 2 2 1 Ribosomal L29 protein zf-H2C2_2 PF13465.6 EJP69618.1 - 3e-24 84.3 21.8 1.6e-06 28.3 0.1 7.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 EJP69618.1 - 1.9e-17 62.6 55.5 0.00023 21.4 0.4 8.8 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EJP69618.1 - 1.2e-10 41.2 22.4 0.0007 19.5 1.2 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EJP69618.1 - 1.6e-10 40.9 55.3 0.0024 18.6 1.3 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-met PF12874.7 EJP69618.1 - 0.0025 18.1 20.7 0.39 11.2 0.5 6.6 6 0 0 6 6 6 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EJP69618.1 - 0.0075 16.0 18.5 0.091 12.5 0.2 4.7 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EJP69618.1 - 0.46 10.4 15.0 0.26 11.3 0.2 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 EJP69618.1 - 0.85 9.7 8.1 17 5.5 0.0 4.4 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 EJP69618.1 - 1.2 9.0 8.1 66 3.4 0.0 4.9 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) LRR_12 PF18837.1 EJP69619.1 - 0.23 11.1 0.6 0.34 10.6 0.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeat ABC_export PF16962.5 EJP69620.1 - 2 6.7 2.4 2.4 6.5 2.4 1.0 1 0 0 1 1 1 0 Putative ABC exporter DEAD PF00270.29 EJP69621.1 - 3e-50 170.4 0.0 2.5e-49 167.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP69621.1 - 2.3e-27 95.5 0.0 1.3e-26 93.1 0.0 2.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain IMS PF00817.20 EJP69622.1 - 5e-43 146.7 0.0 9.2e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EJP69622.1 - 4.3e-14 53.2 0.1 9.9e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EJP69622.1 - 0.00018 21.7 0.0 0.00047 20.3 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Rep_fac_C PF08542.11 EJP69622.1 - 0.15 12.5 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain SUIM_assoc PF16619.5 EJP69623.1 - 0.00078 19.5 2.6 0.0021 18.1 2.6 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 SARAF PF06682.12 EJP69623.1 - 2 7.9 5.6 5 6.7 5.6 1.6 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.8 EJP69623.1 - 9.6 5.7 14.0 0.08 12.5 5.5 1.8 2 0 0 2 2 2 0 Spt20 family AP_endonuc_2 PF01261.24 EJP69624.1 - 1.6e-28 99.6 0.0 2.1e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SDH_C PF18317.1 EJP69625.1 - 1.4e-06 27.9 0.1 2.8e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_dh_N PF08501.11 EJP69625.1 - 8.2e-05 22.8 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 EJP69625.1 - 0.043 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GARS_N PF02844.15 EJP69625.1 - 0.074 13.8 0.1 1 10.2 0.1 2.4 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain zf-CGNR PF11706.8 EJP69625.1 - 0.18 11.7 0.4 0.18 11.7 0.4 1.9 2 0 0 2 2 2 0 CGNR zinc finger Sugar_tr PF00083.24 EJP69626.1 - 1.5e-132 442.7 23.8 1.8e-132 442.5 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP69626.1 - 3.8e-23 82.0 36.9 3.8e-23 82.0 36.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PNKP-ligase_C PF16536.5 EJP69626.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, C-terminal region CR6_interact PF10147.9 EJP69627.1 - 2.8e-05 23.9 1.2 4.9e-05 23.1 1.2 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 EphA2_TM PF14575.6 EJP69627.1 - 0.078 13.9 0.0 0.18 12.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 EJP69627.1 - 0.87 9.4 4.5 2.4 7.9 0.0 2.2 1 1 0 2 2 2 0 Transmembrane protein 51 Flavodoxin_2 PF02525.17 EJP69628.1 - 2.8e-07 30.4 0.0 3.6e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EJP69628.1 - 5.5e-07 29.5 0.0 7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 EJP69628.1 - 0.00035 20.8 0.0 0.02 15.1 0.1 2.3 1 1 1 2 2 2 1 Flavodoxin Raf1_N PF18578.1 EJP69630.1 - 0.028 14.9 0.0 0.028 14.9 0.0 2.0 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain FAM131 PF15010.6 EJP69630.1 - 0.39 10.6 9.5 0.53 10.1 9.5 1.1 1 0 0 1 1 1 0 Putative cell signalling DUF1387 PF07139.11 EJP69630.1 - 2 8.0 10.2 3 7.5 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CDK5_activator PF03261.15 EJP69630.1 - 2.1 7.8 13.5 2.8 7.4 13.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF3176 PF11374.8 EJP69632.1 - 1.2e-23 83.3 0.4 2.7e-23 82.2 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Arginase PF00491.21 EJP69633.1 - 5.7e-82 275.4 0.8 7e-82 275.1 0.8 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EJP69633.1 - 0.055 13.7 0.4 0.083 13.1 0.4 1.3 1 0 0 1 1 1 0 UPF0489 domain WD40 PF00400.32 EJP69634.1 - 5.8e-29 99.7 5.2 5.1e-07 30.3 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP69634.1 - 2.2e-15 56.7 0.0 3.2e-06 27.3 0.0 3.7 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJP69634.1 - 0.00034 20.6 0.0 0.27 11.1 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cornichon PF03311.14 EJP69635.1 - 4.7e-50 169.0 13.2 5.4e-50 168.8 13.2 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M24 PF00557.24 EJP69636.1 - 3e-49 167.6 0.2 3.6e-49 167.3 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EJP69636.1 - 2e-18 66.4 10.6 2e-18 66.4 10.6 1.7 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EJP69636.1 - 0.0022 18.1 7.3 0.0022 18.1 7.3 2.2 2 0 0 2 2 2 1 MYND finger FAD_binding_3 PF01494.19 EJP69637.1 - 8.5e-17 61.4 0.0 2.7e-16 59.8 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EJP69637.1 - 8.2e-06 25.3 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJP69637.1 - 1.2e-05 25.4 0.0 4.8e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP69637.1 - 8.4e-05 23.1 0.0 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP69637.1 - 0.0021 17.7 0.0 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EJP69637.1 - 0.0054 16.1 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EJP69637.1 - 0.0064 15.2 0.0 0.0099 14.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EJP69637.1 - 0.0077 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EJP69637.1 - 0.02 14.3 0.5 0.039 13.3 0.1 1.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase SE PF08491.10 EJP69637.1 - 0.057 12.5 0.1 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.18 EJP69637.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S8 PF00410.19 EJP69638.1 - 4.1e-14 52.6 0.0 2.8e-12 46.7 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 Helo_like_N PF17111.5 EJP69640.1 - 0.00036 20.0 2.5 0.00073 19.0 2.5 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 EJP69640.1 - 0.011 16.3 0.1 0.52 10.9 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Ank PF00023.30 EJP69640.1 - 0.021 15.3 1.1 0.39 11.2 0.1 3.5 3 0 0 3 3 2 0 Ankyrin repeat SesA PF17107.5 EJP69640.1 - 0.054 13.7 4.7 0.18 12.0 1.2 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1664 PF07889.12 EJP69640.1 - 0.059 13.4 0.8 0.46 10.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EJP69640.1 - 0.22 10.8 5.2 0.57 9.5 4.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 EJP69640.1 - 0.23 11.5 13.6 1.6 8.8 5.2 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 EJP69640.1 - 0.26 11.7 5.3 0.85 10.0 3.8 2.2 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 EJP69640.1 - 0.3 10.4 5.0 0.74 9.1 4.4 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EJP69640.1 - 1.4 8.4 9.4 0.64 9.5 1.3 3.0 3 0 0 3 3 3 0 Intermediate filament protein Syntaxin-6_N PF09177.11 EJP69640.1 - 1.5 9.4 4.6 3.7 8.2 1.8 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 EJP69640.1 - 3.7 6.4 7.7 1.4 7.7 2.8 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EJP69640.1 - 9.1 5.8 8.5 19 4.7 4.5 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Iso_dh PF00180.20 EJP69641.1 - 7.2e-100 334.5 0.0 1.1e-99 333.9 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.11 EJP69641.1 - 0.1 12.7 0.6 0.26 11.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) GTP_EFTU PF00009.27 EJP69642.1 - 2.5e-58 196.8 0.2 4.3e-58 196.1 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EJP69642.1 - 1e-31 109.2 0.0 2.2e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EJP69642.1 - 1.1e-31 108.7 0.1 2.4e-31 107.6 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EJP69642.1 - 4.3e-22 78.0 0.0 9.1e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EJP69642.1 - 1.7e-13 50.7 0.0 3.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EJP69642.1 - 1.2e-06 28.4 0.0 2.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EJP69642.1 - 0.094 12.8 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Asp PF00026.23 EJP69643.1 - 8.7e-67 225.8 7.0 1.1e-66 225.4 7.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP69643.1 - 7.2e-14 52.4 3.4 2e-13 51.0 1.0 2.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJP69643.1 - 1.2e-06 29.0 0.4 0.011 16.3 0.1 3.7 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EJP69643.1 - 0.00081 19.9 0.0 1.2 9.7 0.0 3.4 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EJP69643.1 - 0.06 13.1 0.0 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal GLTT PF01744.20 EJP69643.1 - 3.6 7.5 7.6 0.14 12.0 0.7 2.3 3 0 0 3 3 3 0 GLTT repeat (6 copies) Aminotran_1_2 PF00155.21 EJP69644.1 - 4.6e-41 141.2 0.0 5.6e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EJP69644.1 - 6.2e-07 28.7 0.0 9.1e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 EJP69644.1 - 9e-07 28.0 0.0 1.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 EJP69644.1 - 3e-05 22.7 0.0 4.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EJP69644.1 - 0.00047 19.5 0.0 0.00077 18.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Putative_PNPOx PF01243.20 EJP69645.1 - 7.8e-19 67.7 0.0 1.2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EJP69645.1 - 6.1e-13 48.6 2.6 1.2e-12 47.7 2.6 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 EJP69645.1 - 1.7e-05 25.3 0.0 3.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase IFT57 PF10498.9 EJP69645.1 - 0.11 11.5 1.0 0.15 11.0 1.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FAD_binding_4 PF01565.23 EJP69646.1 - 7.2e-21 74.4 3.5 1.2e-20 73.7 3.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP69646.1 - 0.0023 18.0 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ADH_zinc_N PF00107.26 EJP69648.1 - 8.7e-28 96.9 1.2 1.5e-27 96.1 1.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP69648.1 - 9e-17 62.4 0.0 2.3e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP69648.1 - 1.8e-09 37.4 0.0 4.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EJP69648.1 - 0.0025 18.1 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain XPC-binding PF09280.11 EJP69648.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 XPC-binding domain MFS_1 PF07690.16 EJP69649.1 - 9.3e-36 123.5 35.1 9.3e-36 123.5 35.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MIP PF00230.20 EJP69650.1 - 4e-45 154.3 14.8 5e-45 154.0 14.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sec61_beta PF03911.16 EJP69650.1 - 0.27 11.3 3.6 1.8 8.7 0.1 2.6 2 0 0 2 2 2 0 Sec61beta family ABC2_membrane PF01061.24 EJP69651.1 - 6.5e-38 130.3 19.2 6.5e-38 130.3 19.2 2.1 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EJP69651.1 - 2.6e-23 83.0 0.0 4.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EJP69651.1 - 1.1e-05 25.5 0.3 0.14 12.0 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EJP69651.1 - 7.7e-05 22.0 25.3 7.7e-05 22.0 25.3 2.6 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.6 EJP69651.1 - 0.005 16.6 0.2 0.011 15.5 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EJP69651.1 - 0.0078 15.7 0.0 0.16 11.4 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EJP69651.1 - 0.012 15.8 0.0 0.096 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EJP69651.1 - 0.014 16.0 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EJP69651.1 - 0.015 15.3 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EJP69651.1 - 0.033 13.8 0.1 0.076 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EJP69651.1 - 0.057 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ThrE PF06738.12 EJP69651.1 - 0.096 12.0 4.3 0.31 10.4 4.3 1.8 1 0 0 1 1 1 0 Putative threonine/serine exporter AAA_23 PF13476.6 EJP69651.1 - 0.12 12.9 0.3 0.22 12.0 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EJP69651.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF3419 PF11899.8 EJP69653.1 - 1.4e-162 541.3 0.0 1.9e-162 540.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EJP69653.1 - 2.9e-13 50.0 0.0 7.6e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP69653.1 - 9.4e-10 39.1 0.0 2e-07 31.6 0.0 3.3 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP69653.1 - 3.4e-09 37.4 0.0 1.7e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP69653.1 - 1.6e-07 30.9 0.0 0.00031 20.2 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EJP69653.1 - 2.4e-07 31.3 0.0 8.7e-05 23.1 0.0 3.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP69653.1 - 1.8e-06 27.9 0.0 5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EJP69653.1 - 0.00058 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EJP69653.1 - 0.045 13.2 0.0 0.26 10.7 0.0 2.2 3 0 0 3 3 3 0 Putative methyltransferase CybS PF05328.12 EJP69654.1 - 2.7e-51 172.7 0.0 3.4e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit LrgB PF04172.16 EJP69654.1 - 0.0025 17.4 0.2 0.0041 16.7 0.2 1.3 1 0 0 1 1 1 1 LrgB-like family tRNA-synt_1b PF00579.25 EJP69655.1 - 8e-75 251.9 0.2 1.5e-74 251.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EJP69655.1 - 6e-45 151.9 0.0 2.2e-44 150.1 0.0 1.9 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain NPR2 PF06218.11 EJP69656.1 - 1.5e-123 412.9 0.0 1.1e-101 340.8 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Ribosomal_60s PF00428.19 EJP69656.1 - 0.2 12.2 4.1 0.47 11.1 3.7 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ubiquitin PF00240.23 EJP69657.1 - 5.2e-18 64.6 0.0 7.5e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EJP69657.1 - 8.9e-06 25.5 0.5 2.2e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 EJP69657.1 - 0.00056 20.0 0.0 0.00093 19.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 EJP69657.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EJP69657.1 - 0.011 16.2 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain STI1 PF17830.1 EJP69657.1 - 0.02 14.8 11.2 0.69 9.9 6.4 2.9 2 0 0 2 2 2 0 STI1 domain HOIP-UBA PF16678.5 EJP69657.1 - 0.024 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 EJP69657.1 - 0.034 14.1 3.8 0.075 13.0 3.8 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain ADH_zinc_N PF00107.26 EJP69658.1 - 4.8e-26 91.3 0.0 9.1e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP69658.1 - 1.2e-07 32.8 0.0 2.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP69658.1 - 2.6e-05 24.0 0.0 0.00023 21.0 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EJP69658.1 - 0.00068 19.9 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Molydop_binding PF01568.21 EJP69658.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain PAGK PF15284.6 EJP69658.1 - 0.11 12.4 0.3 0.85 9.6 0.1 2.5 2 1 1 3 3 3 0 Phage-encoded virulence factor IBN_N PF03810.19 EJP69659.1 - 4.9e-09 36.0 0.1 3e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EJP69659.1 - 1e-06 28.9 1.2 1.2e-05 25.4 0.0 3.2 4 0 0 4 4 4 1 Exportin 1-like protein Cse1 PF08506.10 EJP69659.1 - 0.0015 17.5 0.7 0.016 14.1 0.0 2.1 2 0 0 2 2 2 1 Cse1 tRNA-synt_2b PF00587.25 EJP69660.1 - 4.7e-35 121.2 0.0 7.1e-31 107.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EJP69660.1 - 3.9e-06 26.9 0.0 1e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Anticodon binding domain HLH PF00010.26 EJP69661.1 - 1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Maf PF02545.14 EJP69662.1 - 3.8e-48 163.5 0.0 4.4e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Bromodomain PF00439.25 EJP69663.1 - 7.3e-28 96.5 0.4 3.5e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 Bromodomain CDC45 PF02724.14 EJP69663.1 - 0.0087 14.4 7.4 0.013 13.8 7.4 1.2 1 0 0 1 1 1 1 CDC45-like protein Clusterin PF01093.17 EJP69663.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Clusterin CobT PF06213.12 EJP69663.1 - 0.21 10.9 10.7 0.36 10.2 10.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT T2SSM PF04612.12 EJP69664.1 - 0.00035 20.7 0.1 0.21 11.6 0.0 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein M DUF3844 PF12955.7 EJP69665.1 - 8.1e-37 125.6 1.0 1.8e-36 124.5 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EJP69665.1 - 1.7 9.1 14.3 0.18 12.2 9.6 1.9 2 0 0 2 2 2 0 EGF-like domain Fungal_trans PF04082.18 EJP69666.1 - 0.0046 16.0 0.0 0.0089 15.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rhodanese PF00581.20 EJP69667.1 - 8.1e-07 29.5 0.0 1.1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain LSM PF01423.22 EJP69668.1 - 1.9e-21 75.5 0.3 2.1e-21 75.4 0.3 1.0 1 0 0 1 1 1 1 LSM domain FUSC PF04632.12 EJP69669.1 - 0.19 10.3 3.5 0.28 9.7 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Macoilin PF09726.9 EJP69669.1 - 0.84 8.1 12.0 0.013 14.1 3.9 1.8 2 0 0 2 2 2 0 Macoilin family p450 PF00067.22 EJP69670.1 - 2.4e-51 175.0 0.0 3.5e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 STI1 PF17830.1 EJP69671.1 - 1.6e-37 127.2 18.1 5.5e-20 71.0 4.9 2.8 2 0 0 2 2 2 2 STI1 domain TPR_1 PF00515.28 EJP69671.1 - 2.3e-37 125.3 25.5 7.1e-06 25.6 0.3 9.7 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 EJP69671.1 - 4.7e-29 98.1 29.4 0.00093 19.1 0.1 9.8 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 EJP69671.1 - 1.8e-14 53.7 12.2 2.1e-10 40.8 0.7 5.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJP69671.1 - 2.7e-14 52.6 15.6 0.0056 16.3 0.3 7.4 5 2 3 8 8 8 5 TPR repeat TPR_16 PF13432.6 EJP69671.1 - 5.4e-13 49.4 7.3 0.00049 20.7 0.0 6.0 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EJP69671.1 - 9.7e-12 44.7 3.9 1.3 10.0 0.0 8.0 4 3 5 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJP69671.1 - 3.3e-11 42.5 31.4 0.00026 21.0 0.4 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EJP69671.1 - 3.6e-11 43.4 8.0 0.0021 18.6 0.0 6.2 5 2 1 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJP69671.1 - 2.5e-10 40.0 2.2 1.3 9.5 0.1 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJP69671.1 - 7.5e-10 38.1 3.4 0.025 14.6 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJP69671.1 - 8.1e-07 29.1 0.0 0.04 14.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EJP69671.1 - 0.00088 19.1 11.0 0.38 10.7 0.1 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP69671.1 - 0.0055 16.9 3.2 0.29 11.4 1.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 EJP69671.1 - 0.036 13.5 0.1 7.1 6.2 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR TPR_6 PF13174.6 EJP69671.1 - 0.71 10.6 20.2 1.4 9.7 0.1 7.2 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF5113 PF17140.4 EJP69671.1 - 0.87 9.4 7.6 30 4.4 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) MIT PF04212.18 EJP69671.1 - 3 8.0 15.5 2.6 8.2 0.2 5.7 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 EJP69671.1 - 4.8 7.3 9.0 24 5.0 0.1 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat Zip PF02535.22 EJP69672.1 - 6.1e-57 193.3 0.1 8.6e-57 192.8 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter MFS_1 PF07690.16 EJP69673.1 - 5.2e-24 84.8 43.9 1e-23 83.9 33.1 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 EJP69673.1 - 0.055 13.9 0.2 0.055 13.9 0.2 3.0 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 Hemerythrin PF01814.23 EJP69674.1 - 6.9e-06 26.7 1.6 1.1e-05 26.1 1.6 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Ctr PF04145.15 EJP69675.1 - 1.9e-32 112.9 0.4 2.2e-32 112.7 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Fungal_trans_2 PF11951.8 EJP69676.1 - 1.5e-41 142.5 0.0 1.9e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69676.1 - 1.3e-06 28.4 6.2 2.3e-06 27.6 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRIQK PF15168.6 EJP69676.1 - 0.18 11.7 0.5 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family MARVEL PF01284.23 EJP69678.1 - 2.4e-05 24.4 13.3 3.4e-05 23.9 13.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain ENTH PF01417.20 EJP69679.1 - 3.5e-45 153.1 0.0 5.1e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EJP69679.1 - 0.00093 18.3 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 ANTH domain Pro_isomerase PF00160.21 EJP69680.1 - 3.2e-42 144.5 0.3 3.6e-42 144.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.12 EJP69681.1 - 9.9e-102 340.8 0.0 1.2e-101 340.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 EJP69681.1 - 0.0045 17.6 0.4 0.082 13.6 0.0 2.8 3 1 1 4 4 4 1 Replication protein A C terminal HTH_36 PF13730.6 EJP69681.1 - 0.0062 16.5 0.0 0.49 10.4 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain Ribosomal_S25 PF03297.15 EJP69681.1 - 0.008 16.4 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.20 EJP69681.1 - 0.045 14.1 0.0 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator B-block_TFIIIC PF04182.12 EJP69681.1 - 0.049 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MarR PF01047.22 EJP69681.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 MarR family EndIII_4Fe-2S PF10576.9 EJP69681.1 - 0.43 11.0 2.1 1 9.8 2.1 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Hist_deacetyl PF00850.19 EJP69682.1 - 2.9e-82 276.6 0.0 4.9e-82 275.8 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.21 EJP69683.1 - 5.9e-33 113.3 0.0 1e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EJP69683.1 - 2.2e-11 44.2 0.4 4.8e-11 43.1 0.4 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EJP69683.1 - 1.6e-06 27.9 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Carb_bind PF10645.9 EJP69684.1 - 3.9e-13 49.4 7.1 3.9e-13 49.4 7.1 2.4 2 1 0 2 2 2 1 Carbohydrate binding Pkinase PF00069.25 EJP69685.1 - 5e-69 232.6 0.0 1.1e-68 231.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69685.1 - 1.3e-32 113.1 0.0 5.2e-31 107.9 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP69685.1 - 0.001 18.4 0.3 1.5 8.1 0.1 2.7 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EJP69685.1 - 0.0017 17.2 0.2 0.014 14.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EJP69685.1 - 0.008 16.1 0.2 0.23 11.4 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 EJP69685.1 - 0.036 13.6 0.6 0.071 12.7 0.6 1.5 1 0 0 1 1 1 0 RIO1 family Ndc1_Nup PF09531.10 EJP69685.1 - 0.13 10.9 0.5 0.21 10.2 0.4 1.6 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DSPc PF00782.20 EJP69686.1 - 9.1e-06 25.5 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EJP69686.1 - 0.011 15.8 0.1 0.044 13.9 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 EJP69686.1 - 0.035 13.7 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EJP69686.1 - 0.038 14.0 0.3 0.15 12.0 0.1 2.1 2 1 0 2 2 2 0 Tyrosine phosphatase family DUF442 PF04273.13 EJP69686.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative phosphatase (DUF442) MFS_1 PF07690.16 EJP69687.1 - 6.1e-28 97.7 31.6 6.1e-28 97.7 31.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5316 PF17247.2 EJP69687.1 - 2.1 8.4 4.6 41 4.3 2.6 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5316) Tetraspanin PF00335.20 EJP69687.1 - 6.5 6.4 8.2 8.5 6.0 3.1 2.7 3 0 0 3 3 3 0 Tetraspanin family DUF1275 PF06912.11 EJP69688.1 - 2.2e-47 161.5 10.9 2.6e-47 161.3 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.6 EJP69688.1 - 0.49 10.0 10.5 1 9.0 0.1 3.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) Cupin_1 PF00190.22 EJP69689.1 - 1.8e-40 138.0 0.0 3.4e-19 68.9 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EJP69689.1 - 5e-26 90.2 1.0 8.2e-13 47.9 0.2 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EJP69689.1 - 1.4e-09 37.5 0.0 0.00069 19.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EJP69689.1 - 5.9e-08 32.7 0.2 0.00064 19.6 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EJP69689.1 - 0.00011 22.1 0.0 0.025 14.5 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.14 EJP69689.1 - 0.019 15.1 0.3 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.12 EJP69689.1 - 0.025 14.2 0.0 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase GPI PF06560.11 EJP69689.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DUF3931 PF13082.6 EJP69689.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) Sulfate_transp PF00916.20 EJP69690.1 - 1.2e-90 304.0 16.3 1.5e-90 303.7 16.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EJP69690.1 - 1e-11 44.5 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain Amino_oxidase PF01593.24 EJP69691.1 - 7.7e-30 104.6 0.4 6.5e-28 98.2 0.4 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJP69691.1 - 9.4e-10 38.6 0.2 6.8e-09 35.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EJP69691.1 - 5.5e-09 35.2 0.9 0.00035 19.4 0.6 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EJP69691.1 - 1.2e-07 31.2 0.8 2.1e-07 30.4 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EJP69691.1 - 3.5e-06 26.3 0.0 0.017 14.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 EJP69691.1 - 5e-06 25.9 0.1 8.5e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EJP69691.1 - 7.7e-06 25.5 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EJP69691.1 - 1.5e-05 24.8 4.0 5.2e-05 23.0 4.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EJP69691.1 - 0.00012 21.5 0.0 0.00023 20.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EJP69691.1 - 0.00094 18.4 0.1 0.0021 17.2 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EJP69691.1 - 0.0016 17.8 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP69691.1 - 0.0018 17.6 0.0 0.0096 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EJP69691.1 - 0.029 13.7 2.5 0.032 13.5 0.8 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EJP69691.1 - 0.072 13.7 0.2 0.26 11.8 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP69691.1 - 0.073 13.1 0.1 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Peptidase_S9 PF00326.21 EJP69692.1 - 1.3e-41 142.4 0.0 1.9e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EJP69692.1 - 5.2e-08 32.8 0.9 8.1e-05 22.3 0.7 2.6 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EJP69692.1 - 9e-08 31.7 1.5 0.01 15.1 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP69692.1 - 0.0025 17.5 1.6 1.1 8.8 1.2 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 EJP69692.1 - 0.0049 16.8 0.1 0.019 14.9 0.1 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EJP69692.1 - 0.009 15.6 0.0 0.031 13.8 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 EJP69692.1 - 0.015 15.4 0.0 0.34 11.0 0.0 2.6 2 0 0 2 2 2 0 TAP-like protein LIP PF03583.14 EJP69692.1 - 0.05 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase FSH1 PF03959.13 EJP69692.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LPD7 PF18821.1 EJP69692.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 Tannase PF07519.11 EJP69692.1 - 0.093 11.6 0.0 0.66 8.8 0.0 2.0 2 0 0 2 2 2 0 Tannase and feruloyl esterase PD40 PF07676.12 EJP69692.1 - 0.11 12.5 0.1 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.16 EJP69692.1 - 0.11 12.3 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Egh16-like PF11327.8 EJP69693.1 - 2.4e-54 184.6 11.7 2.4e-54 184.6 11.7 2.1 2 0 0 2 2 2 1 Egh16-like virulence factor STELLO PF03385.17 EJP69694.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 STELLO glycosyltransferases Pkinase PF00069.25 EJP69695.1 - 2.1e-33 115.8 0.0 3e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69695.1 - 4.4e-17 62.2 0.0 1.2e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP69695.1 - 0.0014 18.0 0.0 0.0032 16.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJP69695.1 - 0.023 14.6 0.0 0.087 12.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Herpes_capsid PF06112.11 EJP69696.1 - 0.33 11.0 7.5 0.59 10.2 7.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Slx4 PF09494.10 EJP69697.1 - 5.3e-24 83.9 0.1 9.5e-24 83.1 0.1 1.4 1 0 0 1 1 1 1 Slx4 endonuclease NUDIX PF00293.28 EJP69697.1 - 4.1e-07 30.1 0.0 8.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S21e PF01249.18 EJP69698.1 - 4.4e-40 135.7 0.2 9e-40 134.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S21e FAD_binding_7 PF03441.14 EJP69699.1 - 2.1e-83 278.8 0.3 2.1e-83 278.8 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EJP69699.1 - 4.5e-38 130.8 0.2 7.7e-38 130.1 0.2 1.4 1 0 0 1 1 1 1 DNA photolyase Acetyltransf_1 PF00583.25 EJP69700.1 - 2.9e-08 34.0 0.0 3.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJP69700.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EJP69700.1 - 0.014 16.0 0.0 0.02 15.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain XLF PF09302.11 EJP69701.1 - 5.1e-51 173.4 0.0 9.2e-51 172.5 0.0 1.4 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Forkhead PF00250.18 EJP69702.1 - 4.7e-19 68.4 0.3 1e-18 67.4 0.3 1.5 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 EJP69703.1 - 1.1e-58 198.2 6.9 1.9e-58 197.5 6.9 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EJP69703.1 - 1.6e-51 173.4 8.2 1.1e-49 167.5 1.9 2.4 1 1 1 2 2 2 2 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 EJP69703.1 - 0.0097 16.3 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Pneumo_att_G PF05539.11 EJP69703.1 - 0.066 12.8 2.3 0.13 11.9 2.3 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G HJURP_mid PF12346.8 EJP69703.1 - 0.27 11.7 12.3 0.055 13.9 1.9 3.0 3 0 0 3 3 3 0 Holliday junction recognition protein-associated repeat Fungal_trans PF04082.18 EJP69704.1 - 8.1e-21 74.2 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69704.1 - 2.9e-09 36.9 11.0 5.3e-09 36.1 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UAA PF08449.11 EJP69705.1 - 5e-10 39.1 18.6 6.3e-10 38.8 18.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EJP69705.1 - 9.5e-05 22.6 9.4 9.5e-05 22.6 9.4 2.2 2 0 0 2 2 2 1 EamA-like transporter family Ribosomal_L14 PF00238.19 EJP69706.1 - 6.2e-33 113.5 0.0 7.3e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Herpes_UL14 PF03580.14 EJP69707.1 - 0.038 14.2 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DUF5427 PF10310.9 EJP69708.1 - 6.3e-172 572.7 0.2 8.9e-172 572.2 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Sugar_tr PF00083.24 EJP69709.1 - 1.2e-78 265.0 14.3 1.4e-78 264.7 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP69709.1 - 3.9e-30 105.0 28.2 7.9e-26 90.8 20.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EJP69709.1 - 4.2e-07 28.9 17.6 0.0012 17.5 4.7 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein DUF4118 PF13493.6 EJP69709.1 - 0.0068 16.2 0.4 0.0068 16.2 0.4 3.5 2 1 0 3 3 3 1 Domain of unknown function (DUF4118) L27_N PF09060.10 EJP69709.1 - 0.2 11.7 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 L27_N Ras PF00071.22 EJP69710.1 - 5.7e-41 139.8 0.0 1.9e-40 138.1 0.0 1.9 2 1 0 2 2 2 1 Ras family Roc PF08477.13 EJP69710.1 - 3.4e-29 101.5 0.0 1.1e-28 99.9 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mannosidase_ig PF17786.1 EJP69710.1 - 3.2e-13 50.1 0.2 1.5e-12 48.0 0.1 2.2 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EJP69710.1 - 4.3e-12 46.7 0.0 1.4e-11 45.0 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Arf PF00025.21 EJP69710.1 - 3.5e-10 39.6 0.0 1.5e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ig_mannosidase PF17753.1 EJP69710.1 - 0.00012 21.8 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 EJP69710.1 - 0.00021 21.3 0.0 0.00057 19.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain MMR_HSR1 PF01926.23 EJP69710.1 - 0.0024 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EJP69710.1 - 0.0036 16.7 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Glyco_hydro_2_C PF02836.17 EJP69710.1 - 0.022 13.9 0.1 0.047 12.8 0.1 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain PduV-EutP PF10662.9 EJP69710.1 - 0.026 14.3 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EJP69710.1 - 0.047 13.4 0.0 0.75 9.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EJP69710.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EJP69710.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EJP69710.1 - 0.055 14.0 0.0 0.51 10.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 EJP69710.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain adh_short PF00106.25 EJP69711.1 - 4.5e-35 120.9 0.1 5.4e-35 120.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP69711.1 - 1e-29 103.8 0.1 1.2e-29 103.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP69711.1 - 1e-09 38.6 0.6 2.5e-09 37.3 0.6 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EJP69711.1 - 0.037 13.0 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EJP69711.1 - 0.037 13.9 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 EJP69711.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EJP69712.1 - 3.1e-45 153.7 0.0 3.2e-44 150.4 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJP69712.1 - 8.2e-06 25.5 0.0 1.9e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EJP69712.1 - 0.062 13.5 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zip PF02535.22 EJP69713.1 - 1.6e-58 198.5 3.2 1.9e-58 198.3 3.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter NPP1 PF05630.11 EJP69714.1 - 1.6e-05 25.1 1.2 3.6e-05 24.0 1.2 1.5 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) Avl9 PF09794.9 EJP69715.1 - 1.1e-140 468.6 0.0 1.5e-140 468.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EJP69715.1 - 3.2e-05 23.8 0.0 0.0014 18.5 0.0 2.4 1 1 0 1 1 1 1 Stabilization of polarity axis Cullin PF00888.22 EJP69716.1 - 2e-190 634.5 13.3 2.5e-190 634.2 13.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EJP69716.1 - 7.6e-26 89.9 2.9 2.8e-25 88.1 2.9 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 EJP69716.1 - 0.0014 19.1 0.6 0.016 15.7 0.4 2.8 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal MARVEL PF01284.23 EJP69717.1 - 0.86 9.6 3.7 1.3 9.1 3.7 1.3 1 0 0 1 1 1 0 Membrane-associating domain Methyltransf_23 PF13489.6 EJP69718.1 - 1.2e-08 34.9 0.1 1e-07 31.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP69718.1 - 9.6e-07 28.7 0.0 5.7e-06 26.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP69718.1 - 7.4e-06 26.5 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP69718.1 - 0.00018 22.2 0.0 0.00046 20.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP69718.1 - 0.0055 17.4 0.0 0.028 15.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJP69718.1 - 0.21 10.9 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EJP69718.1 - 0.25 11.2 0.0 8 6.2 0.0 2.1 1 1 1 2 2 2 0 Hypothetical methyltransferase WD40 PF00400.32 EJP69719.1 - 3.9e-21 75.0 7.2 3.2e-05 24.6 0.1 5.1 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 EJP69719.1 - 1.1e-05 24.3 6.1 0.42 9.2 0.1 4.2 2 2 2 4 4 4 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EJP69719.1 - 0.0005 20.3 0.0 6.7 7.1 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EJP69719.1 - 0.064 12.0 0.0 0.4 9.4 0.0 2.1 2 1 0 2 2 2 0 Nup133 N terminal like APG6_N PF17675.1 EJP69719.1 - 0.81 10.2 4.0 1.6 9.2 4.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 EJP69719.1 - 1.9 8.8 5.8 3.3 8.0 3.5 2.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Sec34 PF04136.15 EJP69720.1 - 0.00072 19.5 2.5 0.061 13.2 0.1 2.3 2 0 0 2 2 2 1 Sec34-like family DUF4200 PF13863.6 EJP69720.1 - 0.0027 18.1 7.8 0.25 11.7 3.9 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) CENP-Q PF13094.6 EJP69720.1 - 0.0046 17.2 7.9 0.0046 17.2 7.9 3.5 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin_1 PF12718.7 EJP69720.1 - 0.0074 16.4 5.5 0.43 10.7 0.1 2.4 2 0 0 2 2 2 1 Tropomyosin like TMF_DNA_bd PF12329.8 EJP69720.1 - 0.016 15.2 1.0 0.016 15.2 1.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ax_dynein_light PF10211.9 EJP69720.1 - 0.017 15.1 10.2 0.96 9.4 4.7 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain YabA PF06156.13 EJP69720.1 - 0.052 14.2 5.5 0.95 10.1 0.1 2.5 2 0 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 EJP69720.1 - 0.056 13.2 11.6 0.96 9.3 6.2 2.4 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 EJP69720.1 - 0.073 13.4 3.7 5 7.5 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 EJP69720.1 - 0.1 12.4 8.3 0.97 9.2 4.1 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 Snf7 PF03357.21 EJP69720.1 - 0.1 12.2 7.5 0.22 11.1 7.5 1.6 1 0 0 1 1 1 0 Snf7 SHE3 PF17078.5 EJP69720.1 - 0.12 12.1 6.7 1.3 8.7 0.8 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.5 EJP69720.1 - 0.16 12.1 5.2 6.4 6.9 0.1 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation bZIP_1 PF00170.21 EJP69720.1 - 0.18 12.0 11.3 0.86 9.7 0.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor LMBR1 PF04791.16 EJP69720.1 - 0.25 10.2 1.7 0.34 9.8 1.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HIP1_clath_bdg PF16515.5 EJP69720.1 - 0.29 11.7 12.4 0.46 11.1 5.6 2.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5082 PF16888.5 EJP69720.1 - 0.38 11.0 5.6 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Cnn_1N PF07989.11 EJP69720.1 - 0.41 10.8 7.7 3.1 8.0 0.4 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 EJP69720.1 - 0.47 10.4 6.8 2.6 8.0 0.5 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Snapin_Pallidin PF14712.6 EJP69720.1 - 0.49 10.8 9.0 0.37 11.2 1.0 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Sec20 PF03908.13 EJP69720.1 - 0.52 10.3 4.2 1.1 9.2 0.4 2.5 2 0 0 2 2 2 0 Sec20 GAS PF13851.6 EJP69720.1 - 0.68 9.3 11.8 1.1 8.6 5.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 EJP69720.1 - 0.7 10.2 9.7 3.3 8.0 0.4 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 BRE1 PF08647.11 EJP69720.1 - 0.82 9.8 11.5 0.26 11.4 4.6 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase WDCP PF15390.6 EJP69720.1 - 0.95 7.8 3.2 1.7 7.0 3.2 1.4 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SlyX PF04102.12 EJP69720.1 - 1 10.1 9.6 8.3 7.1 0.4 3.2 3 0 0 3 3 3 0 SlyX OmpH PF03938.14 EJP69720.1 - 2.3 8.5 8.8 4.9 7.5 8.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rootletin PF15035.6 EJP69720.1 - 2.4 8.2 13.5 2.8 7.9 3.6 2.7 3 0 0 3 3 2 0 Ciliary rootlet component, centrosome cohesion Fungal_TACC PF12709.7 EJP69720.1 - 4 8.0 7.9 5.2 7.6 0.2 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins SOGA PF11365.8 EJP69720.1 - 4 8.6 10.0 2.7 9.2 2.6 3.0 2 1 1 3 3 2 0 Protein SOGA ADIP PF11559.8 EJP69720.1 - 4.2 7.4 17.6 0.55 10.3 0.6 2.9 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding Med9 PF07544.13 EJP69720.1 - 4.4 7.5 9.7 14 5.8 0.6 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4446 PF14584.6 EJP69720.1 - 4.7 7.2 6.4 9 6.3 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DivIVA PF05103.13 EJP69720.1 - 6.8 6.8 15.8 0.23 11.6 8.9 2.1 2 1 0 2 2 1 0 DivIVA protein Prefoldin PF02996.17 EJP69720.1 - 6.9 6.6 8.8 7.7 6.5 0.3 2.6 3 0 0 3 3 2 0 Prefoldin subunit KxDL PF10241.9 EJP69720.1 - 7.8 6.8 13.4 4.5 7.6 3.7 2.8 3 0 0 3 3 2 0 Uncharacterized conserved protein Cupin_8 PF13621.6 EJP69721.1 - 6.4e-32 111.3 0.0 1.1e-31 110.5 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EJP69721.1 - 5.6e-07 29.3 0.0 7.5e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 EJP69721.1 - 0.00095 19.6 0.0 0.0081 16.6 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Arg_decarbox_C PF17944.1 EJP69721.1 - 0.03 14.9 0.6 3.1 8.4 0.1 2.9 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Cupin_2 PF07883.11 EJP69721.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Aconitase PF00330.20 EJP69722.1 - 4.1e-161 537.1 0.0 5.2e-161 536.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EJP69722.1 - 5.1e-41 140.1 0.0 9e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2418 PF10332.9 EJP69723.1 - 4.6e-36 123.2 0.3 2.5e-35 120.9 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 EJP69724.1 - 5.9e-34 116.3 0.1 6.7e-34 116.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 EJP69725.1 - 1.1e-28 100.3 0.2 1.3e-28 100.1 0.2 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EJP69725.1 - 0.00037 20.9 0.0 0.00069 20.0 0.0 1.4 1 1 0 1 1 1 1 ML-like domain Alph_Pro_TM PF09608.10 EJP69725.1 - 0.079 12.8 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) PHD PF00628.29 EJP69726.1 - 4.7e-08 32.8 9.5 1.6e-07 31.1 9.2 2.0 2 0 0 2 2 2 1 PHD-finger SET PF00856.28 EJP69726.1 - 5.2e-06 26.9 0.0 3.6e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 SET domain Glycos_transf_4 PF00953.21 EJP69727.1 - 2.3e-30 105.7 7.7 2.3e-30 105.7 7.7 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 MFS_1 PF07690.16 EJP69728.1 - 7.8e-47 159.9 34.2 7.8e-47 159.9 34.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP69728.1 - 3.3e-10 39.4 22.3 5e-10 38.8 22.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EJP69728.1 - 0.0051 15.3 4.6 0.0074 14.7 4.6 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Transglut_core PF01841.19 EJP69729.1 - 1.5e-08 35.0 0.1 3.4e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 EJP69729.1 - 0.14 13.2 0.3 0.14 13.2 0.3 2.3 2 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase F-box PF00646.33 EJP69730.1 - 9.9e-05 22.1 0.3 0.00025 20.8 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EJP69730.1 - 0.00022 21.0 0.4 0.00054 19.8 0.4 1.7 1 0 0 1 1 1 1 F-box-like Fea1 PF07692.11 EJP69730.1 - 0.0053 15.9 0.5 0.0089 15.1 0.5 1.3 1 0 0 1 1 1 1 Low iron-inducible periplasmic protein Iso_dh PF00180.20 EJP69731.1 - 1.5e-99 333.4 0.0 1.8e-99 333.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EJP69731.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Sec5 PF15469.6 EJP69732.1 - 1.6e-37 129.2 0.3 1.1e-36 126.4 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 EJP69732.1 - 8.3e-05 22.6 0.2 8.3e-05 22.6 0.2 3.2 3 0 0 3 3 3 1 Vps51/Vps67 HEPN_SAV2148 PF18725.1 EJP69732.1 - 0.12 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 SAV2148-like HEPN zf-BED PF02892.15 EJP69733.1 - 0.18 11.9 1.0 0.47 10.5 1.0 1.7 1 0 0 1 1 1 0 BED zinc finger Zn_clus PF00172.18 EJP69733.1 - 4.5 7.5 13.3 0.13 12.4 6.5 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.15 EJP69734.1 - 1.8e-06 26.9 0.1 0.032 12.9 0.0 3.0 3 0 0 3 3 3 3 Transferase family PAS_12 PF18095.1 EJP69734.1 - 0.016 14.8 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain Glyco_hydro_92 PF07971.12 EJP69735.1 - 4.4e-135 451.2 1.0 5.4e-135 450.9 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EJP69735.1 - 3.3e-43 148.3 2.8 9e-43 146.9 2.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Fungal_trans_2 PF11951.8 EJP69736.1 - 6.8e-09 35.0 0.0 1.2e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Solute_trans_a PF03619.16 EJP69737.1 - 1.3e-98 329.8 12.4 1.5e-98 329.5 12.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HMG14_17 PF01101.18 EJP69737.1 - 2.2 9.3 12.9 5.9 7.9 12.9 1.7 1 1 0 1 1 1 0 HMG14 and HMG17 GTP_EFTU PF00009.27 EJP69739.1 - 9.8e-68 227.5 0.2 1.5e-67 227.0 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EJP69739.1 - 1.3e-31 108.9 0.0 4.3e-31 107.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EJP69739.1 - 3.4e-21 75.1 0.0 7.7e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EJP69739.1 - 1.9e-13 50.6 0.1 8.4e-13 48.5 0.1 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EJP69739.1 - 7.4e-12 45.2 0.0 1.9e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EJP69739.1 - 0.00026 21.0 0.2 0.00061 19.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EJP69739.1 - 0.19 11.5 0.2 0.71 9.6 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PWI PF01480.17 EJP69740.1 - 3.3e-10 40.1 0.0 7.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EJP69740.1 - 1.7e-07 31.0 0.3 8.6e-06 25.5 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EJP69740.1 - 3e-05 23.9 0.0 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EJP69740.1 - 0.0001 22.1 4.8 0.00022 21.1 4.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.11 EJP69740.1 - 0.00015 22.0 0.2 0.53 10.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) RRM_occluded PF16842.5 EJP69740.1 - 0.00089 19.1 0.0 0.065 13.1 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EJP69740.1 - 0.0076 16.5 1.6 0.028 14.6 0.0 2.4 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 EJP69740.1 - 0.036 14.1 0.1 0.036 14.1 0.1 2.5 3 0 0 3 3 3 0 RNA binding motif zf_CCCH_4 PF18345.1 EJP69740.1 - 0.045 13.8 3.5 0.11 12.6 3.5 1.7 1 0 0 1 1 1 0 Zinc finger domain RRM_5 PF13893.6 EJP69740.1 - 0.084 12.5 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EssA PF10661.9 EJP69740.1 - 1.5 8.7 5.5 2.7 7.8 5.5 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA PEARLI-4 PF05278.12 EJP69740.1 - 3.3 7.2 8.0 5.8 6.4 8.0 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF3425 PF11905.8 EJP69741.1 - 6.3e-13 48.8 2.7 3.6e-09 36.7 0.1 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3425) MTHFR PF02219.17 EJP69742.1 - 1.9e-110 368.7 0.0 3.3e-110 367.9 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Lactamase_B PF00753.27 EJP69743.1 - 5.6e-21 75.5 1.4 8.9e-21 74.8 1.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EJP69743.1 - 0.00017 21.1 0.7 0.00025 20.6 0.7 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF202 PF02656.15 EJP69744.1 - 7.1e-17 61.6 0.5 1.3e-16 60.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fungal_trans PF04082.18 EJP69745.1 - 7.2e-11 41.6 0.0 1.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69745.1 - 1e-09 38.4 7.2 1.7e-09 37.6 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 EJP69746.1 - 6.7e-07 29.5 0.0 5.1e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pyr_redox_2 PF07992.14 EJP69748.1 - 9.2e-10 38.2 0.0 4.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP69748.1 - 0.00069 19.6 0.0 0.099 12.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EJP69748.1 - 0.0018 17.9 0.6 0.032 13.8 0.6 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Aminotran_1_2 PF00155.21 EJP69748.1 - 0.059 12.5 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II K_oxygenase PF13434.6 EJP69748.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Sacchrp_dh_NADP PF03435.18 EJP69748.1 - 0.16 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 EJP69748.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 ThiF family Rhodanese PF00581.20 EJP69749.1 - 2.1e-16 60.4 0.0 1.6e-08 35.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Lactamase_B PF00753.27 EJP69750.1 - 7.3e-16 58.8 1.1 1.5e-15 57.8 1.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EJP69750.1 - 5e-05 22.9 0.1 7.6e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1442 PF07279.11 EJP69750.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) MFS_1 PF07690.16 EJP69752.1 - 3.7e-28 98.5 17.6 3.7e-28 98.5 17.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EJP69752.1 - 0.044 12.1 0.0 0.069 11.4 0.0 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CENP-B_dimeris PF09026.10 EJP69752.1 - 0.39 11.1 7.5 2 8.9 0.2 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Homeobox_KN PF05920.11 EJP69754.1 - 9.4e-17 60.6 1.4 2.3e-16 59.4 1.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 EJP69754.1 - 2e-15 56.6 9.1 8.8e-07 28.9 0.1 4.9 4 1 0 4 4 4 2 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 EJP69754.1 - 6.6e-06 25.9 0.7 1.4e-05 24.8 0.7 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 EJP69754.1 - 0.0017 18.7 13.5 0.041 14.3 3.9 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP69754.1 - 0.0033 18.1 3.8 0.0033 18.1 3.8 5.1 4 0 0 4 4 4 1 C2H2-type zinc finger A2L_zn_ribbon PF08792.10 EJP69754.1 - 0.11 12.3 0.0 0.35 10.6 0.0 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain Zn_clus PF00172.18 EJP69754.1 - 0.31 11.2 3.5 0.86 9.8 3.5 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Vac17 PF17321.2 EJP69754.1 - 0.77 9.1 2.6 0.5 9.8 0.4 1.7 2 0 0 2 2 2 0 Vacuole-related protein 17 GATA PF00320.27 EJP69755.1 - 6.8e-31 105.6 15.4 6.4e-16 57.7 2.7 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EJP69755.1 - 3.4e-06 26.5 4.6 0.015 14.8 0.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 EJP69755.1 - 4.4e-05 23.5 2.2 0.22 11.6 0.2 2.9 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 EJP69755.1 - 0.00049 20.2 5.2 0.29 11.3 0.4 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 EJP69755.1 - 0.011 15.6 12.6 0.14 12.1 1.3 2.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 EJP69755.1 - 0.017 15.2 6.3 1.4 9.1 0.1 2.9 3 0 0 3 3 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 EJP69755.1 - 0.022 14.7 4.5 1.1 9.1 0.5 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.7 EJP69755.1 - 0.022 14.7 11.2 1 9.4 0.5 3.1 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EJP69755.1 - 0.084 12.3 11.1 1.8 8.1 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain TDP43_N PF18694.1 EJP69755.1 - 0.2 11.5 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain zf-CHY PF05495.12 EJP69755.1 - 0.42 11.1 3.8 3.9 8.0 0.2 2.5 2 0 0 2 2 2 0 CHY zinc finger zinc_ribbon_2 PF13240.6 EJP69755.1 - 4 7.3 12.2 7.7 6.4 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain SPRY PF00622.28 EJP69756.1 - 0.0046 17.1 0.0 0.037 14.1 0.0 2.3 2 0 0 2 2 2 1 SPRY domain SMC_Nse1 PF07574.13 EJP69757.1 - 1.9e-68 230.2 1.0 4e-68 229.2 1.0 1.6 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EJP69757.1 - 3e-15 56.2 8.2 6.3e-15 55.2 8.2 1.6 1 0 0 1 1 1 1 RING-like domain SCIMP PF15050.6 EJP69757.1 - 0.04 14.4 0.4 15 6.1 0.0 2.9 3 0 0 3 3 3 0 SCIMP protein zf-HC5HC2H PF13771.6 EJP69757.1 - 4.6 7.6 10.2 0.12 12.6 2.0 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain Clr2 PF10383.9 EJP69758.1 - 5.9e-10 40.1 0.5 5.3e-09 37.0 0.0 2.6 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 EJP69758.1 - 4.8e-06 27.3 3.4 4.8e-06 27.3 3.4 2.3 2 1 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 DUF4050 PF13259.6 EJP69758.1 - 0.11 12.8 2.5 0.2 12.0 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) TFIIA PF03153.13 EJP69758.1 - 0.55 10.2 14.4 0.77 9.7 14.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EJP69758.1 - 6.2 5.4 6.4 8.9 4.9 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2867 PF11066.8 EJP69759.1 - 0.088 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) Siva PF05458.12 EJP69759.1 - 9.9 5.8 16.1 4.6 6.9 4.0 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Ank_2 PF12796.7 EJP69760.1 - 2.3e-31 108.2 8.8 1.9e-11 44.4 0.3 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP69760.1 - 8.3e-25 86.8 1.3 4.6e-07 30.3 0.0 6.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EJP69760.1 - 2.3e-20 72.1 20.3 0.039 14.4 0.0 10.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EJP69760.1 - 8.4e-20 68.8 9.1 0.1 13.2 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat NACHT PF05729.12 EJP69760.1 - 5e-12 46.0 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 EJP69760.1 - 2.1e-09 37.4 7.3 0.22 11.9 0.0 6.6 3 2 3 7 7 7 5 Ankyrin repeats (many copies) F-box-like PF12937.7 EJP69760.1 - 1.9e-08 34.1 0.1 3.8e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like PNP_UDP_1 PF01048.20 EJP69760.1 - 7.4e-07 28.7 0.8 3.6e-06 26.4 0.8 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily F-box PF00646.33 EJP69760.1 - 2.8e-06 27.0 0.0 5.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain AAA_16 PF13191.6 EJP69760.1 - 0.028 14.8 0.0 0.093 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Asp PF00026.23 EJP69763.1 - 2.2e-10 40.5 1.1 4.2e-10 39.6 1.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Mucin PF01456.17 EJP69763.1 - 0.00059 19.8 0.5 0.00059 19.8 0.5 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein SKG6 PF08693.10 EJP69763.1 - 0.0057 16.0 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4381 PF14316.6 EJP69763.1 - 0.082 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 EJP69763.1 - 0.15 13.0 0.0 0.45 11.4 0.0 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3382 PF11862.8 EJP69763.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Adeno_E3_CR2 PF02439.15 EJP69763.1 - 0.23 11.3 0.0 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Flavodoxin_1 PF00258.25 EJP69764.1 - 1.5e-28 99.8 0.0 2.7e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EJP69764.1 - 3.9e-24 85.5 0.0 5.6e-22 78.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 EJP69764.1 - 3.6e-10 40.4 0.0 2.3e-07 31.4 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 EJP69764.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_5 PF12724.7 EJP69764.1 - 0.23 11.7 0.0 6.3 7.0 0.0 2.4 1 1 1 2 2 2 0 Flavodoxin domain NOA36 PF06524.12 EJP69764.1 - 4.3 6.6 5.8 8.1 5.7 5.8 1.4 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 EJP69765.1 - 3.6e-31 106.8 0.2 2.8e-15 55.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP69765.1 - 2e-05 24.6 0.0 0.02 15.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EJP69765.1 - 0.00097 18.7 0.0 0.95 9.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EJP69765.1 - 0.067 13.2 0.3 8.1 6.5 0.1 2.7 3 0 0 3 3 3 0 DbpA RNA binding domain DUF4783 PF16022.5 EJP69765.1 - 0.078 13.1 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) ArfGap PF01412.18 EJP69766.1 - 2.8e-32 111.3 0.3 5.8e-32 110.2 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ETF PF01012.21 EJP69767.1 - 7.1e-44 149.9 2.2 8.5e-44 149.6 2.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CPSase_L_D2 PF02786.17 EJP69768.1 - 1.7e-113 377.3 0.2 2.3e-84 282.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EJP69768.1 - 2.2e-48 163.3 0.0 5.1e-48 162.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EJP69768.1 - 1.6e-46 158.5 0.0 4.3e-46 157.1 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EJP69768.1 - 3.4e-45 153.7 0.0 7.5e-45 152.6 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EJP69768.1 - 1.2e-38 132.1 0.0 3.3e-38 130.8 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EJP69768.1 - 2e-28 99.5 0.0 3.9e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EJP69768.1 - 6.7e-23 80.7 0.0 6.9e-22 77.5 0.0 2.7 3 0 0 3 3 3 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EJP69768.1 - 4.5e-17 62.3 0.7 1.2e-07 31.5 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EJP69768.1 - 2e-16 60.1 0.1 4.5e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EJP69768.1 - 1e-10 41.5 0.0 1.8e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DJ-1_PfpI PF01965.24 EJP69768.1 - 1.2e-05 25.2 0.1 0.028 14.2 0.0 3.9 4 0 0 4 4 3 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 EJP69768.1 - 1.3e-05 25.3 0.5 0.066 13.3 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EJP69768.1 - 1.6e-05 24.8 2.2 0.00069 19.4 0.3 2.8 2 1 0 2 2 2 1 Peptidase C26 RimK PF08443.11 EJP69768.1 - 0.00024 20.8 0.0 0.079 12.5 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.19 EJP69768.1 - 0.00097 19.0 1.9 1 9.1 0.1 3.0 4 0 0 4 4 4 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 EJP69768.1 - 0.037 14.3 0.3 1.6 9.0 0.0 3.4 3 0 0 3 3 3 0 TrkA-N domain GATase PF00117.28 EJP69769.1 - 1.4e-46 158.7 0.0 1.8e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EJP69769.1 - 1.8e-45 153.9 0.0 5e-45 152.5 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EJP69769.1 - 1.4e-05 25.0 0.2 0.0017 18.2 0.1 2.8 1 1 1 2 2 2 2 Peptidase C26 DJ-1_PfpI PF01965.24 EJP69769.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family SAP PF02037.27 EJP69770.1 - 1.1e-11 44.1 0.4 1.8e-11 43.5 0.4 1.3 1 0 0 1 1 1 1 SAP domain GREB1 PF15782.5 EJP69770.1 - 8.9 3.3 4.9 11 3.0 4.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HNH_2 PF13391.6 EJP69771.1 - 4.8e-05 23.4 0.1 0.00012 22.2 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease WD40 PF00400.32 EJP69772.1 - 9.8e-33 111.7 7.2 1.7e-07 31.8 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP69772.1 - 7e-10 39.1 1.0 0.00013 22.2 0.1 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EJP69772.1 - 2.9e-05 23.0 0.1 0.014 14.2 0.0 2.5 1 1 1 2 2 2 2 Nup133 N terminal like WD40_like PF17005.5 EJP69772.1 - 0.00016 21.1 0.1 1.1 8.5 0.0 3.5 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 EJP69772.1 - 0.0075 15.0 0.2 2.3 6.8 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EJP69772.1 - 0.059 12.3 0.0 0.18 10.7 0.0 1.8 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS_1 PF07690.16 EJP69773.1 - 3e-12 46.1 8.6 3e-12 46.1 8.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP69773.1 - 0.002 17.1 2.5 0.003 16.5 2.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EJP69773.1 - 0.13 10.6 2.5 0.17 10.2 2.5 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Gasdermin PF04598.12 EJP69775.1 - 0.02 14.4 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Gasdermin pore forming domain AbiEi_3 PF11459.8 EJP69775.1 - 0.097 12.4 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system DJ-1_PfpI PF01965.24 EJP69776.1 - 1.3e-10 41.4 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EJP69776.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like Hamartin PF04388.12 EJP69777.1 - 5.1e-15 55.2 45.3 1.9e-13 50.0 45.1 3.7 1 1 0 1 1 1 1 Hamartin protein RMP PF14996.6 EJP69777.1 - 2.9 8.1 9.2 0.24 11.6 3.6 2.1 2 0 0 2 2 2 0 Retinal Maintenance Spc7 PF08317.11 EJP69777.1 - 8.8 5.1 38.9 0.37 9.6 18.1 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Glyco_hydro_17 PF00332.18 EJP69778.1 - 6e-07 29.3 0.8 1.2e-06 28.3 0.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 SOG2 PF10428.9 EJP69778.1 - 1.2 8.2 9.3 1.7 7.7 9.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Zip PF02535.22 EJP69779.1 - 2.5e-54 184.7 7.5 7.8e-54 183.1 7.5 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Phage_holin_Dp1 PF16938.5 EJP69779.1 - 0.13 12.5 0.5 0.37 11.0 0.5 1.8 1 0 0 1 1 1 0 Putative phage holin Dp-1 Terpene_synth_C PF03936.16 EJP69780.1 - 0.032 13.6 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain Syja_N PF02383.18 EJP69782.1 - 3.8e-86 289.3 0.0 4.9e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Fibritin_C PF07921.12 EJP69782.1 - 0.17 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Fibritin C-terminal region Oxidored_FMN PF00724.20 EJP69783.1 - 6.6e-85 285.4 0.0 8e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ras PF00071.22 EJP69784.1 - 9e-58 194.4 0.1 1e-57 194.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJP69784.1 - 7.6e-36 123.0 0.1 1.2e-35 122.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP69784.1 - 1.7e-14 53.6 0.0 2.1e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJP69784.1 - 1.2e-06 28.1 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EJP69784.1 - 1.3e-06 28.1 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EJP69784.1 - 1.6e-06 28.2 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP69784.1 - 4.9e-05 23.3 0.6 0.17 11.8 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EJP69784.1 - 0.026 14.9 0.1 0.051 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 EJP69784.1 - 0.093 11.9 0.1 0.71 9.0 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 EJP69784.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Mitofilin PF09731.9 EJP69785.1 - 3.4e-144 482.1 24.8 4.6e-125 418.9 21.3 2.2 2 0 0 2 2 2 2 Mitochondrial inner membrane protein DUF3987 PF13148.6 EJP69785.1 - 0.6 9.1 6.4 0.12 11.3 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) Synaptobrevin PF00957.21 EJP69785.1 - 7.5 6.4 6.1 1.8 8.4 0.9 2.7 3 0 0 3 3 3 0 Synaptobrevin Mur_ligase_C PF02875.21 EJP69786.1 - 0.00032 20.9 0.3 0.043 14.1 0.1 3.4 2 1 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 EJP69786.1 - 0.045 13.7 0.0 7.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Mur ligase middle domain Mur_ligase_M PF08245.12 EJP69787.1 - 0.037 14.0 0.0 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 Mur ligase middle domain Mur_ligase_C PF02875.21 EJP69787.1 - 0.096 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain GPHH PF16905.5 EJP69787.1 - 0.18 11.6 0.1 1.3 8.9 0.1 2.5 2 1 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Lactamase_B_2 PF12706.7 EJP69788.1 - 2.4e-05 23.9 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EJP69788.1 - 0.00067 19.7 0.0 0.0024 17.9 0.0 1.9 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EJP69788.1 - 0.022 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain GFA PF04828.14 EJP69789.1 - 2.7e-12 46.8 10.3 4.3e-07 30.2 0.0 2.8 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Prefoldin_3 PF13758.6 EJP69790.1 - 1.1e-28 99.1 2.7 3.6e-28 97.5 2.7 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 EJP69790.1 - 1.6e-16 60.9 0.0 1.6e-16 60.9 0.0 5.2 5 1 0 5 5 5 1 Domain of unknown function (DUF3835) NPV_P10 PF05531.12 EJP69790.1 - 0.086 13.3 6.5 5.5 7.5 1.5 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_GPO PF05929.11 EJP69790.1 - 0.76 9.3 0.0 0.76 9.3 0.0 2.8 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Csm1_N PF18504.1 EJP69790.1 - 1.1 9.7 9.7 3.8 7.9 0.4 3.4 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF3562 PF12085.8 EJP69791.1 - 0.038 13.6 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) NolB PF17398.2 EJP69791.1 - 0.069 13.5 0.8 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Nodulation protein NolB Pex19 PF04614.12 EJP69791.1 - 0.07 12.9 0.4 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Pex19 protein family Ribosomal_S17_N PF16205.5 EJP69792.1 - 3.3e-33 113.9 0.2 5.4e-33 113.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EJP69792.1 - 1e-26 92.8 1.6 1.6e-26 92.2 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 Spc7_N PF15402.6 EJP69793.1 - 1.1e-145 487.3 86.7 4.9e-114 382.5 48.4 3.6 2 1 1 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EJP69793.1 - 1.4e-121 405.1 1.5 1.4e-121 405.1 1.5 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EJP69793.1 - 5.8e-21 74.3 1.8 1.1e-20 73.5 1.8 1.5 1 0 0 1 1 1 1 Spc7_C2 Sec34 PF04136.15 EJP69793.1 - 6.3 6.7 6.9 19 5.1 0.1 3.0 3 0 0 3 3 3 0 Sec34-like family Atg14 PF10186.9 EJP69795.1 - 6.6e-66 222.6 0.0 8.4e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 IKKbetaNEMObind PF12179.8 EJP69795.1 - 0.005 16.8 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 I-kappa-kinase-beta NEMO binding domain CSN4_RPN5_eIF3a PF18420.1 EJP69795.1 - 0.14 12.4 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain Formyl_trans_N PF00551.19 EJP69796.1 - 2e-32 112.4 0.0 2.5e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF3807 PF12720.7 EJP69797.1 - 7.2e-40 137.2 4.5 7.2e-40 137.2 4.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3807) DUF1041 PF06292.17 EJP69797.1 - 0.034 14.5 1.0 0.034 14.5 1.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) Pkinase PF00069.25 EJP69798.1 - 4.2e-63 213.2 0.2 4.9e-63 213.0 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69798.1 - 3.3e-19 69.2 0.0 4.5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP69798.1 - 4.1e-10 40.0 0.0 1.6e-06 28.2 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EJP69798.1 - 0.007 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EJP69798.1 - 0.024 14.0 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EJP69798.1 - 0.031 13.9 0.8 0.068 12.7 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase OSTbeta PF15048.6 EJP69799.1 - 0.033 14.3 3.5 0.094 12.9 3.5 1.8 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein VIT1 PF01988.19 EJP69799.1 - 8.2 6.2 6.3 27 4.6 6.3 1.9 1 0 0 1 1 1 0 VIT family APG6 PF04111.12 EJP69800.1 - 4.1e-69 232.1 0.0 7.6e-69 231.2 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EJP69800.1 - 5.9e-34 117.5 13.6 9.1e-34 116.8 13.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF4472 PF14739.6 EJP69800.1 - 0.026 15.2 5.1 0.026 15.2 5.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) TMF_TATA_bd PF12325.8 EJP69800.1 - 0.15 12.3 10.1 0.8 9.9 9.4 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ALC PF17527.2 EJP69800.1 - 0.32 10.6 2.6 0.56 9.8 2.2 1.5 1 1 0 1 1 1 0 Phage ALC protein DUF724 PF05266.14 EJP69800.1 - 0.54 10.1 8.5 0.88 9.4 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EJP69800.1 - 0.73 9.9 8.6 1.2 9.2 8.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Uds1 PF15456.6 EJP69800.1 - 2.6 8.2 13.6 0.18 12.0 7.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Seryl_tRNA_N PF02403.22 EJP69800.1 - 4.5 7.5 10.5 6.6 7.0 9.8 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ABC_tran PF00005.27 EJP69801.1 - 2.6e-53 180.2 0.0 8.1e-31 107.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP69801.1 - 6.2e-30 104.8 21.5 2.8e-25 89.5 7.9 3.0 4 0 0 4 4 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP69801.1 - 1e-09 38.2 0.0 2.8e-06 26.9 0.0 3.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EJP69801.1 - 0.00085 19.3 0.5 0.24 11.3 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EJP69801.1 - 0.0012 18.9 0.2 0.4 10.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EJP69801.1 - 0.0024 18.3 0.3 1.3 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EJP69801.1 - 0.005 17.1 1.2 9.8 6.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain Zip PF02535.22 EJP69801.1 - 0.0076 15.5 1.1 0.71 9.0 0.0 2.8 2 0 0 2 2 2 1 ZIP Zinc transporter T2SSE PF00437.20 EJP69801.1 - 0.0079 15.3 0.0 0.7 8.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EJP69801.1 - 0.0087 15.6 0.0 0.27 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.7 EJP69801.1 - 0.0095 14.9 0.1 1.3 7.9 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.6 EJP69801.1 - 0.015 15.0 0.6 6.1 6.7 0.2 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EJP69801.1 - 0.02 14.4 0.2 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EJP69801.1 - 0.04 13.6 0.1 2.3 7.9 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 EJP69801.1 - 0.12 12.9 4.3 2.9 8.3 0.1 3.4 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EJP69801.1 - 0.13 11.9 0.0 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 EJP69801.1 - 0.14 11.1 1.4 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.6 EJP69801.1 - 0.14 12.4 0.7 26 5.1 0.1 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EJP69801.1 - 0.15 11.7 0.2 14 5.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 EJP69801.1 - 0.31 10.2 0.0 0.31 10.2 0.0 2.4 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 EJP69801.1 - 0.97 9.5 3.8 31 4.6 0.6 3.2 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain CENP-B_dimeris PF09026.10 EJP69801.1 - 1 9.8 6.2 3.2 8.2 6.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4834 PF16118.5 EJP69801.1 - 1.3 10.0 0.0 1.3 10.0 0.0 2.8 3 0 0 3 3 1 0 Domain of unknown function (DUF4834) DUF3464 PF11947.8 EJP69801.1 - 1.6 8.5 3.8 3.6 7.3 0.2 2.7 3 0 0 3 3 2 0 Photosynthesis affected mutant 68 BIRC6 PF12356.8 EJP69801.1 - 1.8 7.9 3.9 4.4 6.7 3.9 1.6 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 FAM176 PF14851.6 EJP69801.1 - 2.5 7.7 10.3 0.088 12.5 0.9 2.6 2 0 0 2 2 2 0 FAM176 family DUF87 PF01935.17 EJP69801.1 - 3.2 7.8 13.3 0.29 11.2 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain CPSF100_C PF13299.6 EJP69801.1 - 6 7.0 6.5 0.82 9.8 0.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal WD40 PF00400.32 EJP69802.1 - 1e-17 64.2 10.7 0.0011 19.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP69802.1 - 2.2e-13 50.3 0.0 0.053 13.8 0.2 5.4 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJP69802.1 - 0.00016 21.6 0.1 0.2 11.5 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 EJP69803.1 - 5e-50 170.4 23.4 4.6e-49 167.2 22.0 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP69803.1 - 1.8e-09 37.0 23.5 1.9e-09 36.9 3.9 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 EJP69803.1 - 0.2 9.9 4.4 0.15 10.3 0.9 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HemY_N PF07219.13 EJP69803.1 - 0.44 10.8 0.1 0.44 10.8 0.1 3.7 5 0 0 5 5 5 0 HemY protein N-terminus DUF1077 PF06417.12 EJP69804.1 - 2e-49 166.5 5.7 2.5e-49 166.2 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 EJP69805.1 - 1.8e-120 403.0 7.2 2.9e-120 402.3 6.9 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 EJP69805.1 - 6.4e-53 179.1 0.1 6.4e-53 179.1 0.1 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJP69805.1 - 8.9e-16 58.1 8.1 3.2e-08 33.8 0.6 5.0 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 EJP69805.1 - 8.6e-10 38.0 5.1 0.0053 16.9 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EJP69805.1 - 0.0005 20.5 9.8 7.7 7.1 0.4 6.3 7 0 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 EJP69805.1 - 0.0066 16.0 2.0 0.35 10.4 0.0 2.9 3 1 0 3 3 3 1 CLASP N terminal RTP1_C1 PF10363.9 EJP69805.1 - 0.022 15.0 1.2 5.8 7.1 0.0 3.6 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EJP69805.1 - 0.054 13.6 4.5 5.5 7.2 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 EJP69805.1 - 0.063 13.0 1.3 8 6.2 0.1 2.8 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 EJP69805.1 - 0.22 11.4 2.8 1 9.2 0.9 2.7 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Rad60-SLD_2 PF13881.6 EJP69806.1 - 4.4e-11 42.9 0.0 7.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EJP69806.1 - 0.00052 19.7 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EJP69806.1 - 0.0017 18.9 0.0 0.003 18.1 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.11 EJP69807.1 - 2.3e-43 147.2 0.0 2.9e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.27 EJP69808.1 - 4.4e-23 82.3 0.0 9.3e-10 39.1 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EJP69808.1 - 7.9e-07 29.2 4.7 0.028 14.3 0.2 3.6 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EJP69808.1 - 2.9e-05 24.2 1.7 0.0086 16.3 0.1 2.6 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EJP69808.1 - 0.00015 22.4 0.0 0.14 12.7 0.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJP69808.1 - 0.00017 21.3 0.1 0.28 10.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP69808.1 - 0.0013 19.0 0.0 0.73 10.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EJP69808.1 - 0.0021 18.3 0.1 1.9 8.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EJP69808.1 - 0.0043 17.4 0.1 3 8.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EJP69808.1 - 0.014 15.2 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EJP69808.1 - 0.018 15.2 0.0 5.7 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 EJP69808.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_18 PF13238.6 EJP69808.1 - 0.025 15.1 0.0 4.1 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EJP69808.1 - 0.036 13.7 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 EJP69808.1 - 0.043 13.6 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 EJP69808.1 - 0.052 12.9 0.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EJP69808.1 - 0.057 12.7 0.0 13 5.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 EJP69808.1 - 0.086 12.6 0.1 0.94 9.2 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SMC_N PF02463.19 EJP69808.1 - 0.094 12.1 0.0 2.9 7.3 0.1 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain TniB PF05621.11 EJP69808.1 - 0.14 11.5 0.0 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 EJP69808.1 - 0.16 11.9 0.1 16 5.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 EJP69808.1 - 0.16 12.0 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.21 EJP69808.1 - 0.16 11.4 0.0 5.6 6.4 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_15 PF13175.6 EJP69808.1 - 0.19 11.4 0.0 7.5 6.2 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF202 PF02656.15 EJP69809.1 - 1.3e-17 64.0 2.5 4.1e-17 62.4 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MARVEL PF01284.23 EJP69809.1 - 0.015 15.3 0.1 0.039 14.0 0.1 1.7 1 1 0 1 1 1 0 Membrane-associating domain DUF2427 PF10348.9 EJP69809.1 - 0.091 12.6 2.2 0.12 12.2 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) HEAT PF02985.22 EJP69811.1 - 0.065 13.5 0.2 0.66 10.4 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Mlh1_C PF16413.5 EJP69812.1 - 9.1e-100 333.5 0.0 1.5e-99 332.8 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EJP69812.1 - 8.9e-33 112.5 0.1 1.4e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EJP69812.1 - 5.7e-11 42.4 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EJP69812.1 - 4.2e-05 24.0 0.0 8.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CENP-B_dimeris PF09026.10 EJP69812.1 - 0.025 15.0 8.0 0.063 13.7 8.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EJP69812.1 - 0.6 9.8 8.1 1.2 8.8 8.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 EJP69812.1 - 1 8.4 10.1 1.7 7.7 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 EJP69812.1 - 5 5.1 7.8 9.3 4.2 7.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 EJP69812.1 - 8.1 6.7 7.8 25 5.2 7.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EJP69812.1 - 8.9 5.5 10.8 15 4.8 10.8 1.2 1 0 0 1 1 1 0 NOA36 protein zf-CCHC_2 PF13696.6 EJP69813.1 - 0.0067 16.2 2.8 0.016 15.0 2.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EJP69813.1 - 0.025 14.6 4.3 0.099 12.8 4.3 2.1 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EJP69813.1 - 0.65 10.0 5.6 0.74 9.8 0.5 3.2 3 0 0 3 3 3 0 Zinc knuckle HET PF06985.11 EJP69814.1 - 2e-31 109.3 0.0 3.4e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-dskA_traR PF01258.17 EJP69817.1 - 0.063 13.2 0.4 0.063 13.2 0.4 1.7 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger SelR PF01641.18 EJP69817.1 - 0.072 13.2 1.1 0.18 11.9 1.1 1.6 1 0 0 1 1 1 0 SelR domain F-box PF00646.33 EJP69817.1 - 0.084 12.8 1.0 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 F-box domain DUF982 PF06169.12 EJP69818.1 - 0.13 12.3 1.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF982) DUF202 PF02656.15 EJP69820.1 - 0.67 10.4 5.5 22 5.6 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) EST1_DNA_bind PF10373.9 EJP69821.1 - 0.036 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Calici_MSP PF05752.11 EJP69823.1 - 0.021 14.6 0.0 0.07 12.9 0.0 1.8 1 1 0 1 1 1 0 Calicivirus minor structural protein Chromo PF00385.24 EJP69824.1 - 4.7e-06 26.4 1.1 0.051 13.5 0.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Rsd_AlgQ PF04353.13 EJP69824.1 - 0.05 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF3886 PF13025.6 EJP69824.1 - 0.15 12.3 13.6 0.41 10.9 13.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Sas10_Utp3 PF04000.15 EJP69824.1 - 1.3 9.7 3.9 1.1 10.0 0.7 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family R2K_3 PF14243.6 EJP69825.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 F-box PF00646.33 EJP69826.1 - 0.00075 19.3 0.0 0.0021 17.9 0.0 1.9 1 0 0 1 1 1 1 F-box domain Baculo_PEP_C PF04513.12 EJP69827.1 - 3.1e-05 24.0 7.5 0.016 15.3 0.3 3.7 1 1 3 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 EJP69827.1 - 0.00017 21.5 3.7 0.0093 15.9 0.2 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain RRF PF01765.19 EJP69827.1 - 0.0041 17.1 0.7 0.16 11.9 0.1 2.3 2 0 0 2 2 2 1 Ribosome recycling factor DUF2884 PF11101.8 EJP69827.1 - 0.0086 15.6 2.2 0.24 10.9 0.3 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2884) IL13 PF03487.13 EJP69827.1 - 0.043 13.6 3.1 0.098 12.4 0.5 2.3 2 0 0 2 2 2 0 Interleukin-13 Collagen_mid PF15984.5 EJP69827.1 - 0.05 13.3 5.5 0.21 11.3 3.6 2.4 2 1 0 2 2 2 0 Bacterial collagen, middle region Fzo_mitofusin PF04799.13 EJP69827.1 - 0.054 13.1 4.7 3 7.4 1.1 2.6 2 0 0 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.10 EJP69827.1 - 0.055 13.6 3.5 7.5 6.7 0.8 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4456 PF14644.6 EJP69827.1 - 0.068 12.9 0.5 0.26 11.0 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4456) AIP3 PF03915.13 EJP69827.1 - 0.074 12.1 2.0 0.64 9.1 0.2 2.0 2 0 0 2 2 2 0 Actin interacting protein 3 CsbD PF05532.12 EJP69827.1 - 0.094 12.6 0.1 0.26 11.2 0.1 1.7 2 0 0 2 2 1 0 CsbD-like BshC PF10079.9 EJP69827.1 - 0.15 10.8 1.2 8.1 5.1 0.1 2.1 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC DUF2205 PF10224.9 EJP69827.1 - 0.17 11.9 0.6 0.67 10.0 0.1 2.2 2 0 0 2 2 2 0 Short coiled-coil protein Sipho_Gp157 PF05565.11 EJP69827.1 - 0.39 10.7 2.0 4.6 7.2 0.1 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 HsbA PF12296.8 EJP69827.1 - 0.55 10.7 5.7 1.6 9.1 1.5 3.0 2 1 1 3 3 3 0 Hydrophobic surface binding protein A KxDL PF10241.9 EJP69827.1 - 0.55 10.5 5.4 5.5 7.3 0.2 3.0 3 1 0 3 3 3 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 EJP69827.1 - 0.56 10.8 5.7 22 5.7 0.3 3.2 2 2 1 3 3 3 0 Syntaxin 6, N-terminal Mis12 PF05859.12 EJP69827.1 - 0.66 10.0 2.6 6.2 6.9 0.4 2.4 2 1 0 2 2 2 0 Mis12 protein DUF3813 PF12758.7 EJP69827.1 - 0.68 10.3 3.6 1.9 8.9 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3813) RapA_C PF12137.8 EJP69827.1 - 1.3 8.0 6.9 0.39 9.7 0.3 2.5 2 1 1 3 3 3 0 RNA polymerase recycling family C-terminal DLP_helical PF18709.1 EJP69827.1 - 1.5 7.9 4.9 0.97 8.6 0.8 2.2 1 1 1 2 2 2 0 Dynamin-like helical domain DHR10 PF18595.1 EJP69827.1 - 1.7 8.7 7.1 0.17 12.0 0.8 2.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain NACHT PF05729.12 EJP69828.1 - 9.2e-10 38.7 0.2 1.9e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EJP69828.1 - 0.00025 21.3 0.0 0.00082 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP69828.1 - 0.0014 19.0 0.3 0.0042 17.5 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain XPC-binding PF09280.11 EJP69828.1 - 0.065 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 XPC-binding domain AAA_33 PF13671.6 EJP69828.1 - 0.082 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EJP69828.1 - 0.082 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EJP69828.1 - 0.091 13.2 0.0 0.29 11.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RHSP PF07999.11 EJP69828.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon hot spot protein ABC_tran PF00005.27 EJP69828.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EJP69828.1 - 0.25 11.1 0.5 0.62 9.8 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dimer_Tnp_hAT PF05699.14 EJP69829.1 - 2.5e-19 68.9 0.0 5.5e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3435 PF11917.8 EJP69830.1 - 5.9e-06 25.5 1.6 5.9e-06 25.5 1.6 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF3435) DUF3435 PF11917.8 EJP69831.1 - 9.3e-20 70.9 0.2 1.3e-19 70.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) COesterase PF00135.28 EJP69833.1 - 5.8e-85 286.1 0.0 8.1e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EJP69833.1 - 0.0035 17.2 0.1 0.018 14.9 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EJP69833.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family HET PF06985.11 EJP69834.1 - 7.1e-14 52.4 2.2 1.7e-10 41.4 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_8 PF08022.12 EJP69835.1 - 2.5e-09 37.2 0.0 4.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EJP69835.1 - 7.2e-09 35.9 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EJP69835.1 - 0.0042 17.2 10.8 0.03 14.5 8.5 2.5 1 1 1 2 2 2 2 Ferric reductase like transmembrane component DUF4405 PF14358.6 EJP69835.1 - 0.093 13.3 2.3 0.36 11.4 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Pkinase PF00069.25 EJP69836.1 - 1.7e-08 34.2 0.0 2.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP69836.1 - 8.7e-06 25.2 0.1 1.2e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3723 PF12520.8 EJP69837.1 - 5.5e-171 569.7 0.1 1e-170 568.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) DUF3958 PF13125.6 EJP69838.1 - 0.2 11.9 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) FAD_binding_4 PF01565.23 EJP69840.1 - 6.1e-17 61.7 0.8 1.2e-16 60.7 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP69840.1 - 1e-09 38.3 2.0 1.4e-09 37.8 0.2 2.2 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 EJP69840.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding SF3a60_bindingd PF12108.8 EJP69840.1 - 0.063 13.2 0.9 0.11 12.4 0.9 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain TM_PBP2_N PF16296.5 EJP69840.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters Zn_clus PF00172.18 EJP69841.1 - 1.2e-05 25.3 11.6 2.5e-05 24.3 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EJP69843.1 - 1.3e-06 28.4 16.2 2.1e-06 27.7 16.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1929 PF09118.11 EJP69844.1 - 6.9e-21 74.4 0.0 1.4e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 EJP69844.1 - 7.3e-20 71.4 2.2 1.7e-19 70.2 2.2 1.6 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.6 EJP69844.1 - 6.7e-13 48.4 3.0 0.0049 17.1 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EJP69844.1 - 7.6e-08 31.8 1.5 1.2e-05 24.8 0.1 4.2 5 0 0 5 5 5 1 Kelch motif Glyoxal_oxid_N PF07250.11 EJP69844.1 - 4.6e-06 26.0 0.1 0.016 14.4 0.1 2.5 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 EJP69844.1 - 5.1e-06 26.3 3.3 0.0039 17.1 0.2 5.0 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.6 EJP69844.1 - 0.00016 21.6 4.0 1.6 8.8 0.0 5.0 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF5000 PF16391.5 EJP69844.1 - 0.00074 19.7 0.2 0.88 9.7 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function EGF_Tenascin PF18720.1 EJP69844.1 - 0.28 11.3 1.4 1.1 9.4 1.4 2.0 1 0 0 1 1 1 0 Tenascin EGF domain Ank_2 PF12796.7 EJP69845.1 - 1.6e-17 63.8 0.0 1.2e-12 48.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP69845.1 - 2.1e-09 37.7 0.0 0.00046 20.7 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP69845.1 - 6.5e-09 35.9 0.0 0.00072 19.8 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EJP69845.1 - 6.7e-08 32.6 0.0 0.14 12.7 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EJP69845.1 - 4.1e-06 26.7 0.0 0.013 15.9 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat DUF2817 PF10994.8 EJP69845.1 - 0.046 13.1 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) DUF3435 PF11917.8 EJP69846.1 - 9.3e-35 120.3 0.1 1.8e-22 79.9 0.0 3.5 2 1 1 3 3 3 3 Protein of unknown function (DUF3435) Phage_int_SAM_5 PF13102.6 EJP69846.1 - 1e-05 25.8 1.5 0.00037 20.8 1.0 2.7 2 0 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 EJP69846.1 - 0.0073 16.8 1.5 0.018 15.5 0.4 2.3 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Retrotrans_gag PF03732.17 EJP69846.1 - 0.21 11.9 1.1 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein CsbD PF05532.12 EJP69849.1 - 1.5e-15 56.8 22.8 3.1e-10 39.8 3.3 3.8 2 1 1 3 3 3 2 CsbD-like Abhydrolase_6 PF12697.7 EJP69850.1 - 1.1e-18 68.6 3.1 1.1e-18 68.6 3.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP69850.1 - 3.1e-14 52.8 0.0 4.1e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP69850.1 - 2.9e-08 33.7 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EJP69850.1 - 0.00026 20.5 0.0 0.0056 16.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 EJP69850.1 - 0.00075 19.7 0.0 0.0011 19.1 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 EJP69850.1 - 0.0015 18.4 0.1 0.0028 17.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EJP69850.1 - 0.011 15.5 0.0 0.74 9.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 EJP69850.1 - 0.027 14.4 0.0 8.8 6.2 0.0 2.9 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal X PF00739.19 EJP69850.1 - 0.043 13.9 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Trans-activation protein X Abhydrolase_4 PF08386.10 EJP69850.1 - 0.13 12.3 0.0 1.7 8.8 0.0 2.1 1 1 1 2 2 2 0 TAP-like protein Aminotran_5 PF00266.19 EJP69851.1 - 8.5e-93 311.2 0.0 1e-92 311.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EJP69851.1 - 1e-05 25.0 0.1 1.8e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EJP69851.1 - 4e-05 23.1 0.2 0.00024 20.5 0.1 2.2 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EJP69851.1 - 0.019 13.5 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 EJP69851.1 - 0.043 12.5 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.18 EJP69852.1 - 2.5e-68 230.3 8.6 3.1e-68 230.0 8.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EJP69852.1 - 1.7e-14 53.1 0.4 3.1e-14 52.3 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EJP69852.1 - 8.8e-13 47.9 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJP69852.1 - 2.3e-08 33.6 0.1 1e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain TMPIT PF07851.13 EJP69852.1 - 0.17 11.1 5.8 0.83 8.8 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein BRE1 PF08647.11 EJP69852.1 - 5.1 7.2 10.0 2 8.5 0.7 2.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase MOSC PF03473.17 EJP69853.1 - 7.3e-26 90.7 0.0 2.7e-25 88.9 0.0 2.0 2 1 0 2 2 2 1 MOSC domain Fer2 PF00111.27 EJP69853.1 - 1.1e-12 47.7 0.4 2.4e-12 46.6 0.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 EJP69853.1 - 1.4e-09 37.7 0.0 3.3e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 EJP69853.1 - 7.7e-05 23.3 0.1 0.0012 19.5 0.1 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain RRP7 PF12923.7 EJP69854.1 - 5.3e-28 97.5 16.9 5.3e-28 97.5 16.9 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EJP69854.1 - 9.2e-14 51.6 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain DUF3113 PF11310.8 EJP69854.1 - 0.013 15.4 0.2 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) CDRT4 PF15213.6 EJP69854.1 - 0.47 11.1 6.6 0.43 11.2 0.1 2.3 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein Alpha_kinase PF02816.18 EJP69854.1 - 1.3 9.1 4.1 22 5.1 3.0 2.3 1 1 1 2 2 2 0 Alpha-kinase family ADIP PF11559.8 EJP69855.1 - 4.4e-38 130.8 23.3 4.8e-38 130.6 9.5 3.2 3 0 0 3 3 3 2 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EJP69855.1 - 0.00051 19.6 4.5 0.00051 19.6 4.5 3.8 4 0 0 4 4 4 1 Golgin subfamily A member 5 PhoU PF01895.19 EJP69855.1 - 0.0074 16.7 8.0 2.2 8.8 0.0 3.8 2 1 1 3 3 3 2 PhoU domain Prominin PF05478.11 EJP69855.1 - 6.3 4.6 5.8 1.7 6.5 1.1 1.9 2 0 0 2 2 2 0 Prominin RPE65 PF03055.15 EJP69856.1 - 3.7e-103 346.2 0.0 4.7e-103 345.9 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF92 PF01940.16 EJP69856.1 - 5.2e-82 274.8 7.8 7.9e-82 274.2 7.8 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF92 Gln-synt_C PF00120.24 EJP69857.1 - 1.7e-18 66.8 0.0 1.3e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EJP69857.1 - 1.1e-11 44.3 0.0 2.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ASFV_J13L PF05568.11 EJP69858.1 - 2.3 7.9 11.8 2.6 7.8 11.8 1.0 1 0 0 1 1 1 0 African swine fever virus J13L protein FAM199X PF15814.5 EJP69858.1 - 3.2 6.7 8.3 3 6.8 8.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X FSA_C PF10479.9 EJP69858.1 - 5.8 4.9 13.1 6.1 4.9 13.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Herpes_capsid PF06112.11 EJP69858.1 - 8.5 6.4 20.3 10 6.2 20.3 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ADH_N_2 PF16884.5 EJP69859.1 - 2.2e-28 98.3 0.0 4.7e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EJP69859.1 - 5.2e-21 75.0 0.0 8.7e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP69859.1 - 7.6e-09 36.7 0.2 1.7e-08 35.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EJP69859.1 - 0.13 12.0 0.0 6.6 6.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) MFS_1 PF07690.16 EJP69860.1 - 9e-29 100.5 46.6 2.6e-28 98.9 45.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Orf78 PF06024.12 EJP69860.1 - 0.034 14.5 0.1 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 Orf78 (ac78) DUF4064 PF13273.6 EJP69860.1 - 2.4 8.5 8.2 0.62 10.4 0.3 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF5367 PF17329.2 EJP69860.1 - 6.3 7.0 10.7 0.8 9.9 0.5 3.8 3 1 0 3 3 3 0 Family of unknown function (DUF5367) Fringe PF02434.16 EJP69861.1 - 0.0025 17.3 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 EJP69861.1 - 0.0036 17.2 3.4 0.012 15.5 3.4 1.9 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EJP69861.1 - 0.12 12.3 0.5 0.25 11.3 0.5 1.4 1 0 0 1 1 1 0 PAN domain Acetyltransf_1 PF00583.25 EJP69862.1 - 5.1e-06 26.7 0.0 8.8e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP69862.1 - 5.2e-06 26.8 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP69862.1 - 4.4e-05 23.4 0.0 7.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 EJP69863.1 - 2e-36 125.8 0.2 2.5e-36 125.4 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP69863.1 - 1.5e-10 41.5 0.6 2.1e-08 34.6 0.8 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP69863.1 - 1.3e-06 27.9 0.0 5.1e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EJP69863.1 - 6.4e-05 22.3 0.4 0.00032 20.0 0.3 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EJP69863.1 - 0.00054 18.9 0.5 0.39 9.5 0.5 3.0 2 1 1 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.6 EJP69863.1 - 0.00064 19.7 1.9 0.6 10.1 0.0 3.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EJP69863.1 - 0.0029 17.3 1.2 11 5.5 1.3 3.6 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 EJP69863.1 - 0.0032 16.7 1.5 1.8 7.7 0.0 2.9 3 0 0 3 3 3 2 Thi4 family Lycopene_cycl PF05834.12 EJP69863.1 - 0.0053 15.9 1.6 0.93 8.5 0.8 2.4 1 1 1 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 EJP69863.1 - 0.0097 14.7 1.1 0.8 8.3 1.0 3.1 2 1 1 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 EJP69863.1 - 0.01 16.1 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EJP69863.1 - 0.039 13.2 0.4 0.18 11.1 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DNA_processg_A PF02481.15 EJP69863.1 - 0.07 12.4 0.2 0.16 11.2 0.2 1.5 1 0 0 1 1 1 0 DNA recombination-mediator protein A UPF0227 PF05728.12 EJP69863.1 - 0.084 12.8 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF4147 PF13660.6 EJP69863.1 - 0.15 11.6 1.2 0.33 10.4 0.3 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) GIDA PF01134.22 EJP69863.1 - 1.3 8.0 8.7 2.6 7.0 4.2 3.0 2 1 1 3 3 3 0 Glucose inhibited division protein A Methyltransf_25 PF13649.6 EJP69864.1 - 1.1e-06 29.2 0.0 2.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP69864.1 - 2.4e-05 24.3 0.0 3.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EJP69864.1 - 6.2e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EJP69864.1 - 0.00018 22.2 0.0 0.00062 20.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP69864.1 - 0.0015 18.4 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EJP69864.1 - 0.0016 18.2 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase GCD14 PF08704.10 EJP69864.1 - 0.0044 16.7 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.6 EJP69864.1 - 0.0049 17.9 0.0 0.01 16.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJP69864.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 EJP69864.1 - 0.013 15.1 0.0 0.044 13.4 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Fibrillarin PF01269.17 EJP69864.1 - 0.039 13.1 0.0 0.085 12.0 0.0 1.4 2 0 0 2 2 2 0 Fibrillarin Ubie_methyltran PF01209.18 EJP69864.1 - 0.043 13.1 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EJP69864.1 - 0.14 12.8 0.0 0.37 11.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain ABC_membrane PF00664.23 EJP69866.1 - 1.3e-41 143.1 11.7 1.7e-41 142.7 11.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EJP69866.1 - 2e-34 119.1 0.0 1e-33 116.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EJP69866.1 - 7.2e-05 22.3 0.0 0.057 12.8 0.0 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EJP69866.1 - 9.5e-05 22.8 0.0 0.00025 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EJP69866.1 - 0.00082 19.4 0.0 0.0056 16.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EJP69866.1 - 0.0011 19.2 0.0 0.0035 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EJP69866.1 - 0.0016 18.4 0.0 0.0084 16.0 0.0 2.1 3 0 0 3 3 3 1 RsgA GTPase AAA_21 PF13304.6 EJP69866.1 - 0.0018 18.1 0.1 0.047 13.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 EJP69866.1 - 0.0063 16.5 0.0 0.036 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EJP69866.1 - 0.011 16.1 0.0 0.075 13.5 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EJP69866.1 - 0.016 15.4 0.1 0.084 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EJP69866.1 - 0.019 14.7 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EJP69866.1 - 0.027 14.7 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EJP69866.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EJP69866.1 - 0.04 13.5 0.1 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Kinesin PF00225.23 EJP69866.1 - 0.045 12.7 0.1 0.075 11.9 0.1 1.2 1 0 0 1 1 1 0 Kinesin motor domain AAA_18 PF13238.6 EJP69866.1 - 0.052 14.1 0.0 0.17 12.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EJP69866.1 - 0.054 12.8 0.1 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EJP69866.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EJP69866.1 - 0.072 13.6 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EJP69866.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EJP69866.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EJP69866.1 - 0.14 12.0 0.1 0.58 10.1 0.0 2.1 3 0 0 3 3 2 0 NACHT domain FMO-like PF00743.19 EJP69868.1 - 2.7e-48 164.7 0.0 2.7e-38 131.7 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJP69868.1 - 1.2e-11 44.5 0.1 6.3e-11 42.1 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP69868.1 - 4.7e-08 32.6 0.0 4e-07 29.6 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJP69868.1 - 2.4e-06 27.6 0.0 9e-05 22.5 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EJP69868.1 - 5.4e-05 22.5 0.7 9.7e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 EJP69868.1 - 0.00011 21.6 0.1 0.27 10.6 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 EJP69868.1 - 0.00052 19.7 2.1 0.044 13.4 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 EJP69868.1 - 0.00054 20.2 0.1 0.0015 18.7 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EJP69868.1 - 0.0035 17.4 1.0 2.5 8.1 0.0 2.6 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EJP69868.1 - 0.068 13.7 2.9 0.33 11.6 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EJP69868.1 - 0.075 12.4 0.1 0.25 10.7 0.1 1.8 2 0 0 2 2 2 0 ThiF family IlvN PF07991.12 EJP69868.1 - 0.097 12.2 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EJP69868.1 - 0.1 12.8 0.5 4.7 7.5 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 EJP69868.1 - 0.27 11.1 1.6 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Myb_DNA-binding PF00249.31 EJP69869.1 - 1.6e-15 57.0 8.6 2.1e-07 31.0 0.2 4.5 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP69869.1 - 1.1e-10 41.6 9.6 5.1e-07 29.8 0.3 4.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain AAA_16 PF13191.6 EJP69869.1 - 6e-09 36.5 1.8 1.5e-08 35.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EJP69869.1 - 1.1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Fungal_trans_2 PF11951.8 EJP69871.1 - 1.1e-36 126.5 4.5 3.9e-26 91.8 2.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69871.1 - 8.4e-09 35.4 10.9 1.8e-08 34.3 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 EJP69871.1 - 0.13 12.2 7.4 0.52 10.3 7.4 2.1 1 0 0 1 1 1 0 AT hook motif Dabb PF07876.12 EJP69873.1 - 9.5e-24 83.9 0.0 1.1e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4390 PF14334.6 EJP69873.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) zf-rbx1 PF12678.7 EJP69874.1 - 8.4e-10 38.8 0.8 1.7e-09 37.8 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EJP69874.1 - 2.6e-08 34.1 1.6 2.6e-08 34.1 1.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EJP69874.1 - 2e-07 30.8 0.7 3.2e-07 30.1 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP69874.1 - 2.4e-06 27.4 1.2 4.7e-06 26.5 1.2 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EJP69874.1 - 2.8e-06 27.2 0.9 2e-05 24.5 0.1 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EJP69874.1 - 2e-05 24.3 7.5 3.7e-05 23.5 2.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJP69874.1 - 0.0003 20.6 3.9 0.00074 19.3 3.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EJP69874.1 - 0.00056 19.7 1.4 0.00056 19.7 1.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EJP69874.1 - 0.0015 18.1 1.3 0.0015 18.1 1.3 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EJP69874.1 - 0.0046 17.0 1.0 0.024 14.7 1.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EJP69874.1 - 0.012 15.4 0.6 0.012 15.4 0.6 3.0 3 0 0 3 3 3 0 RING-like zinc finger zf-C3H2C3 PF17122.5 EJP69874.1 - 0.27 11.3 4.9 2.8 8.0 1.9 2.8 2 0 0 2 2 2 0 Zinc-finger HSBP1 PF06825.12 EJP69875.1 - 2.9e-16 59.0 0.3 3.4e-16 58.8 0.3 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 EJP69875.1 - 0.0015 18.4 0.4 0.0057 16.5 0.4 1.8 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin CLZ PF16526.5 EJP69875.1 - 0.003 17.9 0.9 0.11 12.9 0.1 1.7 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 EJP69875.1 - 0.0049 16.9 0.2 0.006 16.6 0.2 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 EJP69875.1 - 0.015 14.6 0.3 0.016 14.5 0.3 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin Peptidase_C50 PF03568.17 EJP69875.1 - 0.037 13.2 0.0 0.037 13.2 0.0 1.0 1 0 0 1 1 1 0 Peptidase family C50 NIT PF08376.10 EJP69875.1 - 0.056 13.9 0.1 0.063 13.7 0.1 1.0 1 0 0 1 1 1 0 Nitrate and nitrite sensing HR1 PF02185.16 EJP69875.1 - 0.057 13.5 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Hr1 repeat DNA_repr_REX1B PF14966.6 EJP69875.1 - 0.068 13.8 0.0 0.09 13.4 0.0 1.1 1 0 0 1 1 1 0 DNA repair REX1-B MtrG PF04210.13 EJP69875.1 - 0.12 12.2 0.2 3.3 7.7 0.0 2.0 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G UPF0184 PF03670.13 EJP69875.1 - 0.2 12.1 3.8 0.39 11.1 3.8 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Thioredoxin PF00085.20 EJP69876.1 - 1.5e-58 195.1 0.5 5.2e-29 100.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EJP69876.1 - 2e-24 86.3 1.1 2e-24 86.3 1.1 2.2 3 0 0 3 3 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EJP69876.1 - 8.1e-19 68.1 0.0 3.7e-10 39.6 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EJP69876.1 - 3.1e-17 63.0 0.1 1.5e-08 35.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EJP69876.1 - 2.1e-10 40.6 0.0 0.0002 21.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EJP69876.1 - 2.1e-08 34.3 0.0 0.0015 18.8 0.0 3.5 2 2 0 2 2 2 2 Thioredoxin-like HyaE PF07449.11 EJP69876.1 - 1.8e-07 31.1 0.0 0.014 15.3 0.0 3.1 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EJP69876.1 - 2.4e-07 30.7 0.1 0.012 15.5 0.0 2.4 1 1 1 2 2 2 2 AhpC/TSA family ERp29_N PF07912.13 EJP69876.1 - 2.9e-07 30.7 0.2 0.018 15.2 0.1 2.3 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.6 EJP69876.1 - 9.5e-06 25.6 1.5 0.099 12.6 0.1 3.1 2 1 2 4 4 3 3 Thioredoxin-like domain TraF PF13728.6 EJP69876.1 - 7.4e-05 22.7 0.0 0.4 10.5 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 EJP69876.1 - 0.00015 21.5 0.5 0.32 10.7 0.2 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.6 EJP69876.1 - 0.00022 21.2 0.0 0.52 10.4 0.0 3.0 3 0 0 3 3 2 2 Thioredoxin domain Thioredoxin_9 PF14595.6 EJP69876.1 - 0.00033 20.4 0.0 0.089 12.6 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin CbiA PF01656.23 EJP69876.1 - 0.0024 17.9 0.1 0.02 15.0 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Flagellin_IN PF07196.13 EJP69876.1 - 0.0054 16.9 0.4 12 6.2 0.1 3.4 3 0 0 3 3 3 0 Flagellin hook IN motif Glutaredoxin PF00462.24 EJP69876.1 - 0.0079 16.4 3.2 2.7 8.3 0.5 3.5 2 2 0 2 2 2 1 Glutaredoxin Thioredoxin_5 PF13743.6 EJP69876.1 - 0.046 13.4 1.0 9.8 5.8 0.0 3.1 3 1 1 4 4 4 0 Thioredoxin Band_7_C PF16200.5 EJP69876.1 - 0.21 11.7 1.7 0.65 10.1 1.3 2.1 2 0 0 2 2 1 0 C-terminal region of band_7 Thioredoxin_4 PF13462.6 EJP69876.1 - 2.5 8.2 6.0 29 4.8 0.1 3.3 3 2 2 5 5 5 0 Thioredoxin Ribosomal_S14 PF00253.21 EJP69877.1 - 4e-15 55.3 3.3 4.4e-15 55.2 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e ZZ PF00569.17 EJP69877.1 - 0.17 11.7 4.3 2.1 8.3 4.3 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type GTP_EFTU PF00009.27 EJP69878.1 - 4.7e-57 192.7 0.1 6.2e-57 192.3 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EJP69878.1 - 2e-25 89.3 0.0 3.7e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EJP69878.1 - 4.5e-17 62.2 2.3 1.1e-16 60.9 2.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EJP69878.1 - 1.5e-05 25.0 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP69878.1 - 0.0017 18.3 0.1 0.0046 16.9 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EJP69878.1 - 0.036 13.7 0.2 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EJP69878.1 - 0.1 12.4 0.1 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PGA2 PF07543.12 EJP69879.1 - 8.4e-37 126.2 3.0 1e-36 126.0 3.0 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 zinc_ribbon_9 PF14369.6 EJP69880.1 - 0.11 12.7 1.9 5.7 7.3 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon DUF4428 PF14471.6 EJP69880.1 - 0.49 10.4 1.1 1.8 8.6 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Kelch_3 PF13415.6 EJP69882.1 - 0.3 11.4 1.9 3.5 8.0 0.1 3.3 2 0 0 2 2 2 0 Galactose oxidase, central domain Linker_histone PF00538.19 EJP69883.1 - 4.1e-27 94.3 0.1 4.1e-27 94.3 0.1 1.8 2 1 0 2 2 2 1 linker histone H1 and H5 family RR_TM4-6 PF06459.12 EJP69883.1 - 0.3 10.9 6.0 0.34 10.7 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TSSC4 PF15264.6 EJP69883.1 - 2.2 8.5 9.1 5.5 7.3 0.3 2.2 1 1 1 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 Sec23_trunk PF04811.15 EJP69884.1 - 2.3e-52 178.0 0.0 3.7e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EJP69884.1 - 1.2e-24 86.1 0.0 2.1e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EJP69884.1 - 6.5e-17 62.1 0.0 1.2e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EJP69884.1 - 1.5e-14 53.7 4.9 3.7e-14 52.5 4.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EJP69884.1 - 1.3e-06 28.2 0.0 3.5e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.9 EJP69885.1 - 1.8e-06 28.4 0.0 2.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) tRNA-synt_2 PF00152.20 EJP69886.1 - 5.9e-82 275.3 0.0 8.8e-82 274.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJP69886.1 - 1.8e-09 37.4 0.0 3.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Gti1_Pac2 PF09729.9 EJP69887.1 - 3.2e-44 151.2 2.8 4e-37 128.0 0.2 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family Lactamase_B_6 PF16661.5 EJP69888.1 - 2.2e-63 213.2 0.0 3.8e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EJP69888.1 - 4.4e-31 108.4 4.3 4.4e-31 108.4 4.3 2.9 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 EJP69888.1 - 3.7e-16 58.8 0.0 1e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 EJP69888.1 - 1.6e-15 57.3 0.0 6.5e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain SYS1 PF09801.9 EJP69889.1 - 2.1e-46 157.6 7.2 2.5e-46 157.4 7.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network TPPK_C PF12555.8 EJP69889.1 - 0.029 14.4 2.3 0.029 14.4 2.3 2.9 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal COX6B PF02297.17 EJP69890.1 - 5.1e-19 68.3 0.4 6.5e-19 67.9 0.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb PIP5K PF01504.18 EJP69891.1 - 6.9e-103 343.6 0.1 1.3e-102 342.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MFS_1 PF07690.16 EJP69892.1 - 9.1e-06 24.8 19.1 0.00033 19.7 5.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1618 PF07762.14 EJP69893.1 - 0.0054 17.3 0.5 0.0078 16.8 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1618) Acyl-CoA_dh_1 PF00441.24 EJP69894.1 - 1.4e-24 87.0 0.3 2.2e-24 86.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EJP69894.1 - 1.8e-24 86.6 0.1 3.6e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EJP69894.1 - 2.3e-16 59.8 0.0 4.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EJP69894.1 - 1.1e-05 25.7 0.2 1.9e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 EJP69895.1 - 8e-53 177.9 0.0 8.9e-53 177.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP69895.1 - 0.0036 17.0 0.0 0.0045 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EJP69895.1 - 0.034 14.4 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EJP69895.1 - 0.044 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.12 EJP69896.1 - 2.8e-33 115.3 0.0 5.1e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EJP69896.1 - 2.9e-18 66.0 0.2 1.4e-17 63.8 0.0 2.3 3 0 0 3 3 3 1 FAD-binding domain Ferric_reduct PF01794.19 EJP69896.1 - 6.4e-18 65.1 10.4 6.4e-18 65.1 10.4 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EJP69896.1 - 0.11 13.1 0.0 0.45 11.2 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Ribonuclease_T2 PF00445.18 EJP69897.1 - 8.1e-44 150.0 0.2 1.2e-43 149.5 0.2 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family SKG6 PF08693.10 EJP69898.1 - 0.016 14.6 0.7 0.016 14.6 0.7 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DAP10 PF07213.11 EJP69898.1 - 0.038 13.9 0.4 0.038 13.9 0.4 2.2 2 0 0 2 2 2 0 DAP10 membrane protein Tmemb_40 PF10160.9 EJP69898.1 - 2.2 7.7 3.9 3.1 7.2 3.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein MFS_1 PF07690.16 EJP69899.1 - 3e-36 125.1 28.2 1.5e-35 122.8 28.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2863 PF11062.8 EJP69899.1 - 0.046 12.1 0.0 0.066 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) DUF3784 PF12650.7 EJP69899.1 - 1.8 8.8 7.5 54 4.1 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) DUF3357 PF11837.8 EJP69900.1 - 0.21 12.0 3.4 3.2 8.3 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF515 PF04415.12 EJP69900.1 - 2.2 6.6 3.7 3 6.2 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Zn_clus PF00172.18 EJP69901.1 - 3.6e-10 39.8 10.5 6.2e-10 39.0 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP69901.1 - 0.019 13.8 3.1 0.02 13.7 1.7 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Ank_2 PF12796.7 EJP69902.1 - 1.2e-24 86.7 2.4 2.9e-11 43.8 1.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP69902.1 - 4.8e-21 74.8 0.5 2.5e-07 31.1 0.1 5.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJP69902.1 - 1.6e-13 50.6 0.4 0.0016 18.7 0.1 5.0 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EJP69902.1 - 4.9e-13 48.9 16.3 0.019 15.4 0.1 6.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 EJP69902.1 - 1.1e-11 43.8 2.1 0.89 10.3 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat NdhS PF11623.8 EJP69902.1 - 0.79 9.4 4.2 1.3 8.8 0.1 3.0 2 1 2 4 4 4 0 NAD(P)H dehydrogenase subunit S FLgD_tudor PF13861.6 EJP69902.1 - 8.8 6.6 7.9 9.9 6.5 0.2 3.3 3 1 0 3 3 3 0 FlgD Tudor-like domain Rhomboid PF01694.22 EJP69904.1 - 3.2e-32 111.6 9.4 3.2e-32 111.6 9.4 1.9 3 0 0 3 3 3 1 Rhomboid family HCV_NS2 PF01538.18 EJP69904.1 - 0.052 13.2 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 HPP PF04982.13 EJP69904.1 - 0.058 13.6 0.6 0.13 12.4 0.6 1.5 1 0 0 1 1 1 0 HPP family ASFV_J13L PF05568.11 EJP69904.1 - 5.5 6.7 5.8 1.8 8.3 0.3 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein DNA_pol_B PF00136.21 EJP69905.1 - 1.8e-148 495.1 3.1 2.5e-148 494.6 3.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EJP69905.1 - 6.7e-79 265.5 0.0 1.5e-78 264.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EJP69905.1 - 3.3e-17 62.7 6.7 7.3e-17 61.6 6.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 EJP69905.1 - 0.0011 19.0 1.2 0.0082 16.1 0.2 2.9 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 EJP69905.1 - 0.002 17.1 2.3 0.057 12.3 0.1 2.4 1 1 0 2 2 2 2 DNA polymerase type B, organellar and viral C1_1 PF00130.22 EJP69905.1 - 0.01 15.7 1.0 0.01 15.7 1.0 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_pol_B_exo2 PF10108.9 EJP69905.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB ELFV_dehydrog PF00208.21 EJP69906.1 - 3.4e-83 279.1 5.9 4.2e-83 278.8 5.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EJP69906.1 - 4.4e-51 172.2 0.0 7.4e-51 171.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Qn_am_d_aIV PF09100.10 EJP69906.1 - 0.053 13.3 0.2 0.097 12.5 0.2 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV D-ser_dehydrat PF14031.6 EJP69906.1 - 0.1 13.3 0.1 1.7 9.4 0.0 2.4 2 0 0 2 2 2 0 Putative serine dehydratase domain NAD_binding_7 PF13241.6 EJP69906.1 - 0.1 13.0 0.4 0.25 11.8 0.2 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EJP69906.1 - 0.13 11.6 0.1 0.51 9.7 0.1 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_transf_3 PF02515.17 EJP69907.1 - 1.6e-67 228.3 0.0 4.5e-67 226.8 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III Dynamin_M PF01031.20 EJP69908.1 - 3.2e-102 341.6 0.3 5.4e-102 340.8 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EJP69908.1 - 9.9e-57 191.6 0.0 2e-56 190.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EJP69908.1 - 9e-30 102.7 6.6 2.1e-29 101.5 6.6 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EJP69908.1 - 8.3e-06 25.9 0.2 0.00012 22.1 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EJP69908.1 - 1 9.0 4.4 6.2 6.4 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain WD40 PF00400.32 EJP69909.1 - 6.6e-20 71.1 9.0 0.0013 19.5 0.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP69909.1 - 4e-10 39.9 0.6 0.012 15.8 0.0 5.3 4 3 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 EJP69909.1 - 0.0068 16.4 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat PD40 PF07676.12 EJP69909.1 - 0.031 14.2 0.1 16 5.5 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CAS_CSE1 PF03378.15 EJP69911.1 - 1.5e-167 557.6 0.0 3.6e-167 556.4 0.0 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EJP69911.1 - 3.2e-152 506.7 3.5 4.4e-152 506.2 3.5 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EJP69911.1 - 6.7e-13 48.4 0.1 4.1e-12 45.8 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EJP69911.1 - 1 9.4 3.3 31 4.6 0.0 4.2 6 0 0 6 6 6 0 Exportin 1-like protein DUF3384 PF11864.8 EJP69912.1 - 1.1e-144 483.0 2.6 1.1e-144 483.0 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EJP69912.1 - 1e-55 188.2 0.0 4.6e-55 186.1 0.0 2.1 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.16 EJP69912.1 - 5.8e-39 134.2 4.7 5.7e-35 121.1 0.1 4.0 4 0 0 4 4 4 3 Tuberin Borrelia_P83 PF05262.11 EJP69913.1 - 0.033 12.7 4.2 0.038 12.5 4.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF3_subunit PF08597.10 EJP69913.1 - 0.16 11.9 19.0 0.24 11.3 19.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AP3D1 PF06375.11 EJP69913.1 - 0.36 11.1 17.7 0.59 10.4 17.7 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 CDC45 PF02724.14 EJP69913.1 - 0.54 8.5 8.2 0.67 8.2 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 EJP69913.1 - 0.54 9.0 8.2 0.71 8.6 8.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4820 PF16091.5 EJP69913.1 - 0.65 9.3 7.7 0.99 8.7 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PBP_sp32 PF07222.12 EJP69913.1 - 0.66 9.4 5.9 0.91 8.9 5.9 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sec62 PF03839.16 EJP69913.1 - 0.79 9.2 9.9 1.2 8.6 9.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 EJP69913.1 - 1.4 8.0 3.6 1.8 7.7 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Afi1 PF07792.12 EJP69913.1 - 2.8 8.4 7.9 4.8 7.7 7.9 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 EJP69913.1 - 3.4 7.4 13.9 4.9 6.9 13.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 EJP69913.1 - 4.8 7.0 13.4 8.9 6.1 13.4 1.5 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 EJP69913.1 - 5.5 5.6 9.4 7.7 5.2 9.4 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_E_B PF04042.16 EJP69915.1 - 7.8e-46 156.1 0.0 1.2e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EJP69915.1 - 6.7e-39 133.0 0.0 1.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain ABC_tran PF00005.27 EJP69916.1 - 7.1e-15 55.7 0.0 4.8e-14 53.1 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EJP69916.1 - 7.3e-10 39.1 0.4 0.00019 21.3 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 EJP69916.1 - 0.00067 17.3 0.1 0.00088 16.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 EJP69916.1 - 0.00098 18.8 0.1 0.0029 17.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP69916.1 - 0.0032 17.9 0.5 0.0085 16.5 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EJP69916.1 - 0.0042 16.5 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJP69916.1 - 0.0076 16.8 0.0 0.011 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EJP69916.1 - 0.016 15.6 0.2 0.19 12.2 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EJP69916.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EJP69916.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EJP69916.1 - 0.029 14.6 1.3 0.043 14.1 0.5 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EJP69916.1 - 0.036 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EJP69916.1 - 0.079 13.2 0.1 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EJP69916.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EJP69916.1 - 0.15 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EJP69916.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EJP69916.1 - 0.21 11.0 0.3 0.35 10.3 0.3 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.12 EJP69916.1 - 0.21 11.5 0.2 0.37 10.7 0.2 1.3 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 EJP69916.1 - 0.23 11.5 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Dynamin family CENP-I PF07778.11 EJP69919.1 - 1e-36 126.8 0.3 4.2e-35 121.4 0.0 2.5 2 1 0 2 2 2 1 Mis6 PKHD_C PF18331.1 EJP69919.1 - 0.023 14.8 0.2 1.5 9.0 0.1 2.8 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain PALP PF00291.25 EJP69921.1 - 1.1e-67 228.6 0.2 1.4e-67 228.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4679 PF15728.5 EJP69921.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) CENP-S PF15630.6 EJP69922.1 - 7.9e-35 119.1 0.4 1.1e-34 118.7 0.0 1.4 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 EJP69922.1 - 1.9e-06 27.9 0.1 3.1e-06 27.3 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EJP69922.1 - 0.0038 17.2 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated TFIID-18kDa PF02269.16 EJP69922.1 - 0.0042 17.1 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Lon_2 PF13337.6 EJP69922.1 - 0.016 13.8 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease DUF2773 PF10971.8 EJP69922.1 - 0.062 13.4 0.1 0.088 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) WSC PF01822.19 EJP69923.1 - 3.5e-52 174.5 45.2 6.9e-18 64.6 9.0 3.7 3 0 0 3 3 3 3 WSC domain peroxidase PF00141.23 EJP69923.1 - 5.8e-21 75.2 0.0 1.1e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Moricin PF06451.11 EJP69923.1 - 0.67 9.8 2.6 2.9 7.8 0.0 3.2 4 0 0 4 4 4 0 Moricin Gly-zipper_Omp PF13488.6 EJP69924.1 - 0.01 15.8 5.7 0.021 14.8 5.7 1.5 1 0 0 1 1 1 0 Glycine zipper MGC-24 PF05283.11 EJP69924.1 - 0.014 15.8 4.2 0.014 15.8 4.2 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mid2 PF04478.12 EJP69924.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Romo1 PF10247.9 EJP69924.1 - 0.027 14.8 0.9 0.058 13.8 0.9 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 SKG6 PF08693.10 EJP69924.1 - 0.033 13.6 0.1 0.11 12.0 0.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CYYR1 PF10873.8 EJP69924.1 - 0.051 14.0 0.5 0.11 13.0 0.5 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF4366 PF14283.6 EJP69924.1 - 0.17 12.0 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Phage_HK97_TLTM PF06120.11 EJP69924.1 - 0.18 11.0 0.2 0.27 10.4 0.2 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Gram_pos_anchor PF00746.21 EJP69924.1 - 1.8 8.6 3.9 5.4 7.1 3.9 1.9 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Macoilin PF09726.9 EJP69924.1 - 3.3 6.1 4.0 4.3 5.8 4.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF2236 PF09995.9 EJP69925.1 - 5.1e-44 151.2 2.9 6.2e-44 150.9 1.7 1.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) UPF0242 PF06785.11 EJP69926.1 - 0.0019 18.4 3.1 0.0034 17.5 3.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 EJP69926.1 - 0.032 13.1 5.8 0.079 11.8 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) GvpL_GvpF PF06386.11 EJP69926.1 - 0.056 13.4 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DLP_helical PF18709.1 EJP69926.1 - 0.085 12.0 3.9 0.15 11.3 3.9 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain DUF3713 PF12506.8 EJP69926.1 - 0.14 12.4 1.3 0.4 11.0 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3713) GBP_C PF02841.14 EJP69926.1 - 0.2 11.0 7.8 0.38 10.1 7.8 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DGCR6 PF07324.11 EJP69926.1 - 0.26 10.9 4.8 0.48 10.0 4.8 1.4 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Spc7 PF08317.11 EJP69926.1 - 0.27 10.0 9.3 0.16 10.8 6.9 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 EJP69926.1 - 0.32 9.5 5.1 0.46 9.0 5.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 EJP69926.1 - 5.2 6.2 7.4 9 5.4 7.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein HSP70 PF00012.20 EJP69927.1 - 4.8e-07 28.3 0.0 1.6e-06 26.6 0.0 1.8 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EJP69927.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein APH PF01636.23 EJP69928.1 - 7.1e-08 32.7 0.0 1.6e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2866 PF11065.8 EJP69928.1 - 0.38 10.8 1.8 2.5 8.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) MIS13 PF08202.11 EJP69929.1 - 0.01 15.2 0.3 0.011 15.0 0.3 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF3717 PF12512.8 EJP69929.1 - 0.016 15.1 0.2 0.037 13.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) DUF4164 PF13747.6 EJP69929.1 - 0.019 15.3 3.0 0.084 13.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 EJP69929.1 - 0.1 13.0 0.2 6.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4263 PF14082.6 EJP69929.1 - 0.11 12.8 2.0 8.8 6.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4263) XhlA PF10779.9 EJP69929.1 - 0.14 12.3 0.8 2.6 8.3 0.2 2.0 2 0 0 2 2 2 0 Haemolysin XhlA CENP-H PF05837.12 EJP69929.1 - 0.59 10.6 5.6 2.8 8.4 1.2 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PHO4 PF01384.20 EJP69930.1 - 2.8e-99 332.3 19.0 3.3e-99 332.1 19.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family MARVEL PF01284.23 EJP69931.1 - 6e-06 26.3 14.0 1.1e-05 25.5 14.0 1.5 1 0 0 1 1 1 1 Membrane-associating domain DUF3402 PF11882.8 EJP69932.1 - 2.4e-213 709.4 0.0 3.2e-213 709.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EJP69932.1 - 4.5e-96 321.4 0.0 7.1e-96 320.8 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein CorA PF01544.18 EJP69932.1 - 0.11 11.8 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2011 PF09428.10 EJP69933.1 - 1.1e-22 80.1 0.8 8.3e-22 77.3 0.0 2.2 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) NDT80_PhoG PF05224.12 EJP69934.1 - 7.8e-36 124.0 0.0 1.2e-35 123.4 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family IBR PF01485.21 EJP69935.1 - 1.6e-19 69.9 39.5 3.2e-14 52.9 5.1 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EJP69935.1 - 5.4e-16 58.9 0.0 1.1e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EJP69935.1 - 0.0054 17.0 10.4 0.0054 17.0 10.4 3.9 3 1 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 EJP69935.1 - 0.0063 16.5 8.1 0.0063 16.5 8.1 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 EJP69935.1 - 0.024 14.4 7.6 0.082 12.7 7.6 2.0 1 0 0 1 1 1 0 RING-like zinc finger PAP2 PF01569.21 EJP69936.1 - 7.2e-13 48.5 8.0 2e-12 47.0 5.9 2.3 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EJP69936.1 - 0.0018 18.4 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 2 Divergent PAP2 family Chorion_2 PF03964.15 EJP69936.1 - 0.023 15.5 0.0 0.059 14.2 0.0 1.5 1 1 0 1 1 1 0 Chorion family 2 DUF3963 PF13124.6 EJP69937.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3963) Grg1 PF11034.8 EJP69938.1 - 2.7e-31 107.6 12.5 3e-31 107.4 12.5 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Phe_tRNA-synt_N PF02912.18 EJP69938.1 - 0.02 14.8 0.5 0.031 14.2 0.4 1.4 1 1 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain EBP PF05241.12 EJP69939.1 - 5.6e-70 234.4 7.8 6.5e-70 234.2 7.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein TMEM208_SND2 PF05620.11 EJP69939.1 - 0.07 12.9 6.9 2.4 7.9 1.9 2.5 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 DUF4680 PF15730.5 EJP69939.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) NAD_kinase PF01513.21 EJP69940.1 - 3e-69 233.5 0.0 6.6e-69 232.3 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase PfkB PF00294.24 EJP69941.1 - 1e-15 57.9 0.0 1.9e-12 47.1 0.0 2.4 2 1 0 2 2 2 2 pfkB family carbohydrate kinase PI31_Prot_N PF11566.8 EJP69941.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal Las1 PF04031.13 EJP69944.1 - 3.9e-60 202.4 2.5 7.6e-60 201.5 2.5 1.5 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 EJP69944.1 - 1.3e-21 76.9 0.2 4e-21 75.3 0.2 1.9 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EJP69944.1 - 6e-17 62.3 1.3 1.9e-15 57.4 1.3 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily EF-hand_9 PF14658.6 EJP69944.1 - 0.01 16.2 0.0 0.27 11.6 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain DUF1236 PF06823.12 EJP69944.1 - 0.011 15.6 0.1 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Ribosomal_60s PF00428.19 EJP69944.1 - 0.025 15.2 5.9 0.6 10.7 0.7 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lactamase_B_2 PF12706.7 EJP69944.1 - 0.1 12.1 0.6 0.75 9.3 0.6 2.3 1 1 0 1 1 1 0 Beta-lactamase superfamily domain EF-hand_7 PF13499.6 EJP69944.1 - 0.11 13.0 0.0 0.66 10.5 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair IF4E PF01652.18 EJP69945.1 - 1.5e-36 125.6 0.2 2e-36 125.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E APH PF01636.23 EJP69946.1 - 2.2e-13 50.7 1.5 5.3e-13 49.4 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP69946.1 - 0.0001 22.0 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase HTH_Tnp_Tc5 PF03221.16 EJP69946.1 - 0.00038 20.4 0.1 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain RIO1 PF01163.22 EJP69946.1 - 0.014 15.0 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.17 EJP69946.1 - 0.026 13.8 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase CVNH PF08881.10 EJP69947.1 - 1.7e-13 51.1 0.1 3.4e-13 50.1 0.1 1.6 2 0 0 2 2 2 1 CVNH domain Med13_C PF06333.12 EJP69948.1 - 1.9 7.7 5.8 0.11 11.8 0.4 1.6 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Cwf_Cwc_15 PF04889.12 EJP69948.1 - 5.4 6.7 8.2 0.3 10.8 0.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Kinesin PF00225.23 EJP69949.1 - 8.8e-116 386.5 0.0 1.7e-115 385.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EJP69949.1 - 4.1e-26 91.7 0.8 8.9e-26 90.6 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding GAS PF13851.6 EJP69949.1 - 0.013 14.8 9.8 0.015 14.7 8.4 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EJP69949.1 - 0.021 13.7 9.2 0.034 13.0 8.6 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Noggin PF05806.12 EJP69949.1 - 0.053 13.4 1.7 4.7 7.1 0.5 2.7 2 0 0 2 2 2 0 Noggin DUF3037 PF11236.8 EJP69949.1 - 0.081 13.4 5.1 0.26 11.7 5.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Tau95 PF09734.9 EJP69949.1 - 0.33 11.8 4.6 0.28 12.0 2.6 2.0 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF87 PF01935.17 EJP69949.1 - 0.77 9.8 0.0 0.77 9.8 0.0 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain TBCC_N PF16752.5 EJP69949.1 - 1.2 9.6 10.8 9.8 6.7 9.5 2.9 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain YabA PF06156.13 EJP69949.1 - 3.5 8.3 13.1 20 5.9 0.0 4.0 4 1 1 5 5 5 0 Initiation control protein YabA AT_hook PF02178.19 EJP69950.1 - 0.045 13.6 1.7 0.045 13.6 1.7 7.1 7 1 0 7 7 7 0 AT hook motif zf-C2HE PF16278.5 EJP69951.1 - 8.5e-20 71.0 0.0 1.5e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 EJP69951.1 - 3.7e-14 53.2 2.3 2.9e-13 50.4 2.3 2.1 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EJP69951.1 - 1.6e-13 51.1 6.4 3.7e-06 27.4 3.3 2.7 3 0 0 3 3 3 2 Scavenger mRNA decapping enzyme C-term binding HA2 PF04408.23 EJP69952.1 - 9.4e-18 64.5 0.4 1.3e-16 60.8 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EJP69952.1 - 4.4e-15 56.0 0.0 9.2e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EJP69952.1 - 4e-14 52.7 0.0 8.6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EJP69952.1 - 4.2e-11 42.9 0.1 7.9e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 EJP69952.1 - 2.7e-05 24.4 0.2 5e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 RWD domain DND1_DSRM PF14709.7 EJP69952.1 - 0.005 17.1 0.1 0.015 15.5 0.1 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 ResIII PF04851.15 EJP69952.1 - 0.0063 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EJP69952.1 - 0.013 15.7 2.3 0.11 12.8 2.1 2.5 2 1 0 2 2 1 0 AAA domain ATPase PF06745.13 EJP69952.1 - 0.016 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EJP69952.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EJP69952.1 - 0.053 13.1 0.1 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EJP69952.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein dsRBD2 PF17842.1 EJP69952.1 - 0.071 13.3 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 AAA_23 PF13476.6 EJP69952.1 - 0.087 13.3 0.7 0.27 11.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 EJP69952.1 - 0.097 12.5 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_16 PF13191.6 EJP69952.1 - 0.19 12.1 0.4 1.2 9.5 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Arm PF00514.23 EJP69953.1 - 1.9e-97 316.7 15.6 6.4e-14 51.4 0.3 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EJP69953.1 - 1.3e-27 96.1 1.8 1.3e-27 96.1 1.8 1.8 2 0 0 2 2 1 1 Importin beta binding domain Arm_3 PF16186.5 EJP69953.1 - 1.7e-24 85.1 5.4 3.8e-24 84.0 4.9 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 EJP69953.1 - 6.7e-23 80.8 6.2 7.4e-09 35.9 0.1 6.2 5 1 0 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 EJP69953.1 - 1.6e-19 70.1 0.1 2.1e-08 34.4 0.0 5.1 2 2 2 4 4 4 4 HEAT repeats HEAT PF02985.22 EJP69953.1 - 1.9e-18 65.0 2.5 1.7e-05 24.7 0.0 7.1 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 EJP69953.1 - 4.1e-08 33.0 0.0 0.037 13.5 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 EJP69953.1 - 2e-05 23.4 0.0 0.00043 19.0 0.0 2.5 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 EJP69953.1 - 0.0002 21.5 0.0 6 7.0 0.0 4.3 3 2 1 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.16 EJP69953.1 - 0.00038 20.8 0.3 1.7 9.6 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 EJP69953.1 - 0.0022 18.1 0.0 3.8 7.5 0.0 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 EJP69953.1 - 0.013 15.7 5.5 3.1 8.1 0.0 4.8 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 EJP69953.1 - 0.079 12.8 0.0 7.2 6.5 0.0 3.2 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain PP2C_C PF07830.13 EJP69953.1 - 0.1 13.1 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain POT1PC PF16686.5 EJP69954.1 - 3.7e-46 156.8 0.0 8e-46 155.7 0.0 1.6 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EJP69954.1 - 4.9e-12 45.9 0.0 9.9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 STAG PF08514.11 EJP69955.1 - 5.4e-35 119.7 0.2 2.7e-34 117.5 0.2 2.3 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 EJP69955.1 - 0.002 18.5 0.3 6 7.3 0.1 4.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EJP69955.1 - 0.02 15.1 0.0 27 5.4 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat MFS_1 PF07690.16 EJP69956.1 - 4.4e-16 58.8 61.0 1.1e-12 47.6 62.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP69956.1 - 6.1e-08 31.5 27.1 7.9e-08 31.2 26.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UreD PF01774.17 EJP69957.1 - 8.3e-76 254.6 0.0 1e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein BiPBP_C PF06832.12 EJP69957.1 - 0.12 12.5 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family RNA_pol_Rpc4 PF05132.14 EJP69958.1 - 3.4e-34 118.4 0.0 3.4e-34 118.4 0.0 2.9 2 1 0 2 2 2 1 RNA polymerase III RPC4 NOA36 PF06524.12 EJP69958.1 - 5.9 6.1 6.2 12 5.1 6.2 1.4 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_3 PF07859.13 EJP69960.1 - 3.7e-08 33.5 0.1 8.9e-08 32.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP69960.1 - 3.9e-05 24.3 1.8 7.9e-05 23.4 1.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP69960.1 - 0.00048 19.5 0.1 0.0061 15.9 0.0 2.3 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJP69960.1 - 0.0072 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EJP69960.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DUF3089 PF11288.8 EJP69960.1 - 0.048 13.2 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2974 PF11187.8 EJP69960.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF915 PF06028.11 EJP69960.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Zn_clus PF00172.18 EJP69961.1 - 0.00075 19.6 12.3 0.0013 18.8 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 EJP69961.1 - 0.014 14.8 0.1 0.039 13.4 0.1 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ Cyclin_N PF00134.23 EJP69963.1 - 4.8e-42 142.7 0.6 3.9e-41 139.7 0.2 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EJP69963.1 - 8.9e-35 119.4 0.1 2.7e-34 117.8 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Mito_carr PF00153.27 EJP69964.1 - 5.6e-72 237.8 0.4 2.4e-25 88.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EJP69964.1 - 3e-15 56.4 5.2 4.3e-08 33.5 0.3 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EJP69964.1 - 3e-13 48.3 5.3 8.4e-07 28.1 0.1 5.5 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EJP69964.1 - 3.1e-13 48.5 1.7 2.3e-06 27.1 0.1 5.7 6 0 0 6 6 6 2 EF-hand domain EF-hand_5 PF13202.6 EJP69964.1 - 5.3e-09 35.2 0.2 4.1e-06 26.0 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EJP69964.1 - 1.1e-07 31.5 2.9 2.6 8.0 0.1 5.3 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 EJP69964.1 - 0.11 12.8 0.2 25 5.3 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain Ribosomal_60s PF00428.19 EJP69966.1 - 0.07 13.7 4.9 0.17 12.5 4.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Dyp_perox PF04261.12 EJP69966.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Dyp-type peroxidase family PQ-loop PF04193.14 EJP69967.1 - 5.7e-32 109.3 9.8 1.4e-15 56.8 3.0 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF5368 PF17336.2 EJP69967.1 - 0.018 15.2 0.2 0.038 14.2 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5368) tRNA-synt_1 PF00133.22 EJP69968.1 - 8.9e-51 172.9 0.0 4.7e-10 38.3 0.0 6.1 3 1 3 6 6 6 6 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EJP69968.1 - 6e-41 140.0 0.0 1.3e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EJP69968.1 - 4.5e-28 98.1 0.0 8.6e-20 70.8 0.0 4.5 4 1 1 5 5 5 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EJP69968.1 - 3.2e-12 46.7 0.0 6.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EJP69968.1 - 0.0019 17.6 0.0 0.55 9.5 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 EJP69968.1 - 0.16 10.9 0.2 0.53 9.2 0.1 1.8 1 1 1 2 2 2 0 tRNA synthetases class I (R) zf-ribbon_3 PF13248.6 EJP69968.1 - 0.49 9.9 2.7 6.5 6.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain MTHFR PF02219.17 EJP69969.1 - 3.1e-96 322.1 0.0 4.7e-96 321.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TFIIF_alpha PF05793.12 EJP69970.1 - 9 4.8 7.4 13 4.2 7.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PQ-loop PF04193.14 EJP69971.1 - 7.7e-18 64.0 1.2 5.4e-12 45.3 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EJP69971.1 - 0.094 13.5 4.7 0.37 11.6 4.7 2.0 1 1 0 1 1 1 0 ER lumen protein retaining receptor Phage_holin_5_2 PF16079.5 EJP69971.1 - 0.14 12.5 0.8 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V UPF0542 PF15086.6 EJP69971.1 - 0.3 11.0 3.4 8.6 6.4 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 HemY_N PF07219.13 EJP69971.1 - 0.54 10.5 2.9 15 5.9 0.2 2.4 2 0 0 2 2 2 0 HemY protein N-terminus GCP_N_terminal PF17681.1 EJP69972.1 - 3.4e-33 115.6 0.0 4.8e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EJP69972.1 - 9.3e-30 104.1 0.0 1.6e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 EJP69972.1 - 4.8e-09 35.1 0.0 6.1e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.16 EJP69973.1 - 1.8e-110 369.2 10.7 2.2e-110 368.9 10.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.32 EJP69974.1 - 5.5e-23 80.8 4.2 2.8e-06 28.0 0.3 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP69974.1 - 1.1e-07 32.1 0.0 0.29 11.5 0.0 4.9 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 EJP69975.1 - 7.1e-12 44.9 0.5 2.8e-11 43.0 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP69975.1 - 2.7e-07 30.6 8.4 5.2e-07 29.7 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCCL PF03815.19 EJP69976.1 - 2.7e-19 69.1 0.0 4.9e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 LCCL domain DUF212 PF02681.14 EJP69976.1 - 0.0064 16.6 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 Divergent PAP2 family TGT PF01702.18 EJP69977.1 - 3.4e-76 256.7 0.0 4.3e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Alk_phosphatase PF00245.20 EJP69978.1 - 1.9e-69 234.6 0.1 1.6e-68 231.6 0.1 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EJP69978.1 - 3.5e-07 29.9 0.0 6.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EJP69978.1 - 3.8e-05 23.4 0.3 8.2e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EJP69978.1 - 0.0098 14.5 0.4 0.019 13.6 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 EJP69978.1 - 0.057 12.8 0.2 2.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF1501 PF07394.12 EJP69978.1 - 0.079 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Phage_terminase PF10668.9 EJP69978.1 - 0.21 11.6 1.1 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 Phage terminase small subunit CutC PF03932.14 EJP69979.1 - 3e-35 121.5 0.0 8.7e-35 120.0 0.0 1.6 1 1 0 1 1 1 1 CutC family FMN_dh PF01070.18 EJP69979.1 - 0.0039 16.3 4.1 0.0066 15.5 4.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Peptidase_S10 PF00450.22 EJP69981.1 - 2.6e-67 228.1 0.0 4.1e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase OPT PF03169.15 EJP69982.1 - 3.2e-175 584.3 55.8 3.7e-175 584.1 55.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DoxX PF07681.12 EJP69982.1 - 0.034 14.7 0.1 0.034 14.7 0.1 2.9 3 0 0 3 3 3 0 DoxX TetR_C_31 PF17940.1 EJP69982.1 - 0.23 11.7 0.0 0.44 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Glyco_transf_90 PF05686.12 EJP69983.1 - 6.6e-11 41.7 0.1 3.7e-10 39.3 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 90 DUF4245 PF14030.6 EJP69983.1 - 0.47 10.4 2.1 6.5 6.7 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4245) SPRY PF00622.28 EJP69984.1 - 5.5e-18 65.2 0.0 1.2e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 SPRY domain Exo_endo_phos PF03372.23 EJP69988.1 - 2e-08 34.1 0.4 3e-08 33.5 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Zn_clus PF00172.18 EJP69990.1 - 5.7e-08 32.8 8.1 1.1e-07 31.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP69990.1 - 0.0062 15.4 1.3 0.17 10.7 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain AAA_6 PF12774.7 EJP69990.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Zn_clus PF00172.18 EJP69992.1 - 1.4e-07 31.5 11.2 2.2e-07 30.9 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP69992.1 - 1.2e-05 24.3 0.6 1.9e-05 23.6 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_EZ PF13513.6 EJP69994.1 - 2.7e-33 114.0 19.3 3e-14 53.1 0.1 10.7 9 3 2 11 11 11 6 HEAT-like repeat HEAT PF02985.22 EJP69994.1 - 9.9e-26 87.6 11.5 2.7e-06 27.2 0.0 10.2 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 EJP69994.1 - 5.8e-19 68.3 0.5 9.2e-05 22.8 0.0 6.8 5 1 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 EJP69994.1 - 1.4e-08 34.9 0.0 0.35 10.9 0.0 4.7 3 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EJP69994.1 - 2.1e-08 33.9 0.3 4.5e-07 29.7 0.1 3.4 2 1 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.8 EJP69994.1 - 1.1e-07 31.3 7.8 0.17 10.9 0.0 4.6 4 1 1 5 5 5 4 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EJP69994.1 - 3.4e-07 30.7 0.0 0.18 12.4 0.0 5.3 5 1 2 7 7 7 2 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EJP69994.1 - 0.00041 20.5 0.1 0.11 12.7 0.0 4.0 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EJP69994.1 - 0.00072 19.5 1.1 1.5 9.0 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 EJP69994.1 - 0.0015 18.4 0.1 4.5 7.2 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF3437) HEAT_PBS PF03130.16 EJP69994.1 - 1.6 9.6 5.3 77 4.4 0.0 5.4 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat PAC4 PF16093.5 EJP69995.1 - 6.8e-21 74.2 0.3 9.4e-21 73.8 0.3 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 EJP69996.1 - 1.8e-95 319.2 0.0 2.3e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 EJP69996.1 - 0.00029 21.5 0.0 0.0039 17.9 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP69996.1 - 0.0043 16.9 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP69996.1 - 0.0054 17.4 0.0 0.029 15.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJP69996.1 - 0.035 13.9 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain adh_short_C2 PF13561.6 EJP69997.1 - 3.9e-48 164.0 0.3 5.2e-48 163.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP69997.1 - 2.1e-41 141.5 0.0 5e-41 140.3 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EJP69997.1 - 2.1e-12 47.3 0.1 3.4e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Dicty_CAR PF05462.11 EJP69999.1 - 6.3e-10 38.7 9.3 6.3e-10 38.7 9.3 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 EJP69999.1 - 9.7e-08 31.6 4.0 1.3e-07 31.3 4.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 EJP69999.1 - 0.00078 19.3 13.2 0.0019 18.0 13.2 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 EJP69999.1 - 0.048 12.7 13.5 30 3.5 13.5 2.3 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region Methyltransf_25 PF13649.6 EJP70000.1 - 0.071 13.8 0.0 0.21 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EJP70000.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Xan_ur_permease PF00860.20 EJP70001.1 - 1.2e-25 90.1 28.4 4.7e-24 84.8 26.2 2.9 2 1 0 2 2 2 1 Permease family MFS_MOT1 PF16983.5 EJP70001.1 - 0.0053 17.1 15.4 0.0061 16.9 3.9 2.9 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily DUF4956 PF16316.5 EJP70001.1 - 5 6.8 5.7 0.79 9.4 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) Peptidase_C12 PF01088.21 EJP70002.1 - 7.4e-65 218.6 0.0 9.2e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EJP70002.1 - 1.1e-10 41.2 0.5 1.9e-10 40.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases DUF2407 PF10302.9 EJP70003.1 - 5.9e-05 23.6 0.0 0.0002 21.9 0.0 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EJP70003.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PS_Dcarbxylase PF02666.15 EJP70004.1 - 4.7e-78 261.3 0.0 7.3e-77 257.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase SUIM_assoc PF16619.5 EJP70004.1 - 0.026 14.6 4.2 0.051 13.6 2.9 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Biotin_lipoyl PF00364.22 EJP70004.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme Cyt_b-c1_8 PF10890.8 EJP70004.1 - 0.15 12.5 0.1 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 FAD_binding_1 PF00667.20 EJP70005.1 - 4.9e-42 144.0 0.0 6.9e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EJP70005.1 - 1.1e-09 38.9 0.0 3.4e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain P5-ATPase PF12409.8 EJP70006.1 - 5.8e-38 129.8 0.0 2.2e-37 127.9 0.0 2.1 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EJP70006.1 - 2.2e-28 99.0 0.1 5.8e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EJP70006.1 - 9.8e-15 55.4 0.0 7.6e-09 36.2 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EJP70006.1 - 9.5e-06 25.4 5.5 9.5e-06 25.4 5.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EJP70006.1 - 0.003 17.2 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EJP70006.1 - 0.011 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) NAP PF00956.18 EJP70007.1 - 8.2e-99 330.2 8.7 8.2e-99 330.2 8.7 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Pro_dh PF01619.18 EJP70009.1 - 1.4e-69 234.9 0.0 1.7e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase CGI-121 PF08617.10 EJP70010.1 - 1.4e-52 178.1 0.6 1.6e-52 177.9 0.6 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.18 EJP70011.1 - 5.1e-11 42.1 0.0 8.5e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP70011.1 - 2.5e-08 33.9 5.7 4e-08 33.2 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EJP70012.1 - 9.8e-48 163.0 0.0 1.2e-47 162.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FeS_assembly_P PF01883.19 EJP70012.1 - 0.083 13.1 0.6 0.25 11.6 0.1 2.1 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein zf-C2H2_4 PF13894.6 EJP70013.1 - 2e-08 34.4 2.3 0.0022 18.7 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP70013.1 - 4.9e-07 29.8 3.0 0.0043 17.4 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type LicD PF04991.13 EJP70013.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.3 1 1 0 1 1 1 0 LicD family Ima1_N PF09779.9 EJP70013.1 - 0.13 13.1 0.8 0.22 12.4 0.8 1.8 1 1 0 1 1 1 0 Ima1 N-terminal domain zf-C2H2_11 PF16622.5 EJP70013.1 - 0.14 11.9 0.8 0.31 10.8 0.8 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 EJP70013.1 - 0.16 12.3 0.3 1.1 9.6 0.3 2.2 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 EJP70013.1 - 0.18 12.2 1.7 3.8 7.9 0.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EJP70013.1 - 0.29 11.5 2.7 4.8 7.6 0.9 2.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EJP70013.1 - 0.56 10.3 3.9 12 6.0 0.6 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger CMAS PF02353.20 EJP70014.1 - 7.7e-57 192.7 0.1 9.4e-57 192.4 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EJP70014.1 - 2.6e-08 33.9 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EJP70014.1 - 2.7e-05 23.8 0.0 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 EJP70014.1 - 3.2e-05 24.5 0.0 7.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP70014.1 - 0.00034 21.3 0.0 0.0008 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EJP70014.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SH3_3 PF08239.11 EJP70014.1 - 0.036 14.4 0.1 8.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain Kinesin PF00225.23 EJP70016.1 - 8.7e-117 389.8 0.1 1.2e-116 389.3 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EJP70016.1 - 1.1e-27 96.8 0.0 2.4e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 EJP70016.1 - 0.0021 18.3 1.8 0.0021 18.3 1.8 2.0 2 0 0 2 2 2 1 Herpesvirus UL14-like protein Fungal_trans PF04082.18 EJP70017.1 - 2.1e-07 30.2 0.2 3.4e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP70017.1 - 8.4e-06 25.8 10.7 1.4e-05 25.1 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LPD5 PF18799.1 EJP70017.1 - 0.29 11.5 2.0 0.58 10.6 2.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 Aminotran_5 PF00266.19 EJP70018.1 - 1.1e-08 34.4 0.0 2.6e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EJP70018.1 - 0.05 12.9 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EJP70018.1 - 0.14 10.6 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.18 EJP70019.1 - 5.9e-142 473.5 0.0 7.2e-142 473.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 EJP70019.1 - 0.00038 19.3 0.0 0.074 11.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) 5_nucleotid_C PF02872.18 EJP70020.1 - 4.2e-31 108.3 0.0 9.4e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EJP70020.1 - 3.2e-15 57.2 1.1 6e-15 56.3 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 EJP70020.1 - 0.00026 20.4 0.5 0.00044 19.7 0.5 1.3 1 0 0 1 1 1 1 YmdB-like protein p450 PF00067.22 EJP70021.1 - 9.7e-20 70.7 0.0 1.6e-19 70.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF2183 PF09949.9 EJP70022.1 - 3.6e-33 113.8 0.1 1.6e-32 111.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) S36_mt PF10937.8 EJP70023.1 - 2.5e-43 148.3 1.1 2.9e-43 148.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF4695 PF15766.5 EJP70023.1 - 0.087 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) AA_permease PF00324.21 EJP70024.1 - 1.2e-141 472.6 44.8 1.4e-141 472.4 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP70024.1 - 5.6e-40 137.5 46.6 7.6e-40 137.0 46.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1741 PF08427.10 EJP70025.1 - 7.5e-89 297.4 0.1 1.5e-88 296.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) RasGEF PF00617.19 EJP70026.1 - 2.5e-52 177.7 0.0 4.3e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EJP70026.1 - 1.1e-17 64.2 0.1 3.8e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 EJP70026.1 - 1.8e-08 34.1 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EJP70026.1 - 2e-05 24.1 0.0 4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SQS_PSY PF00494.19 EJP70026.1 - 0.084 12.4 0.1 2 7.9 0.0 2.6 1 1 1 2 2 2 0 Squalene/phytoene synthase MFS_1 PF07690.16 EJP70027.1 - 1.3e-17 63.8 26.0 1.3e-17 63.8 26.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EJP70027.1 - 6.8e-13 48.6 4.8 6.8e-13 48.6 4.8 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 FUSC PF04632.12 EJP70027.1 - 0.087 11.3 1.7 0.16 10.5 1.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3493 PF11998.8 EJP70027.1 - 0.14 12.3 2.7 6.7 7.0 2.1 3.0 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 SLATT_5 PF18160.1 EJP70027.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 NEMP PF10225.9 EJP70027.1 - 0.23 11.1 3.2 0.47 10.1 3.2 1.5 1 0 0 1 1 1 0 NEMP family Abhydrolase_1 PF00561.20 EJP70028.1 - 5.3e-10 39.4 0.0 7.5e-08 32.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP70028.1 - 2.3e-09 38.2 9.2 3.2e-09 37.7 9.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP70028.1 - 6.3e-07 28.9 0.0 2.8e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Glyco_hydro_16 PF00722.21 EJP70029.1 - 7.5e-09 35.3 0.0 1.3e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 bZIP_1 PF00170.21 EJP70030.1 - 3.3e-07 30.3 4.0 7.9e-07 29.1 4.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor ComFB PF10719.9 EJP70030.1 - 0.18 11.9 0.7 0.35 11.0 0.7 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB Stm1_N PF09598.10 EJP70032.1 - 4e-10 40.4 3.0 4e-10 40.4 3.0 4.3 4 1 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 EJP70032.1 - 2.9e-05 24.9 7.7 2.9e-05 24.9 7.7 2.9 3 2 0 3 3 3 1 Hyaluronan / mRNA binding family WW PF00397.26 EJP70033.1 - 5.2e-09 36.0 1.3 1.1e-08 35.0 1.3 1.5 1 0 0 1 1 1 1 WW domain WRW PF10206.9 EJP70033.1 - 0.032 14.6 0.2 0.064 13.6 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Selenoprotein_S PF06936.11 EJP70033.1 - 0.5 10.2 6.3 0.96 9.2 5.3 1.9 2 0 0 2 2 2 0 Selenoprotein S (SelS) RIX1 PF08167.12 EJP70034.1 - 3.7e-56 189.9 0.6 7.9e-56 188.8 0.6 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis ORC_WH_C PF18137.1 EJP70034.1 - 9 6.4 6.2 24 5.0 6.2 1.7 1 1 0 1 1 1 0 Origin recognition complex winged helix C-terminal TPR_14 PF13428.6 EJP70035.1 - 7.8e-11 41.9 12.3 0.0024 18.5 0.0 7.0 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJP70035.1 - 2.8e-10 39.5 7.4 0.033 14.3 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJP70035.1 - 2.3e-07 31.2 2.7 0.026 15.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJP70035.1 - 7.4e-07 29.1 0.3 0.036 14.4 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJP70035.1 - 3.5e-06 26.8 2.7 0.099 12.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJP70035.1 - 2.2e-05 24.1 0.7 0.51 10.2 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP70035.1 - 0.00012 22.3 5.5 1.5 9.2 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EJP70035.1 - 0.00023 21.3 0.7 0.21 11.8 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP70035.1 - 0.00058 20.5 11.4 0.11 13.1 0.1 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EJP70035.1 - 0.02 14.1 0.2 0.28 10.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EJP70035.1 - 0.027 14.5 0.3 4.9 7.4 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJP70035.1 - 0.045 14.4 1.3 1.6 9.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Cytochrom_C_2 PF01322.20 EJP70035.1 - 0.11 13.4 0.1 18 6.2 0.0 3.0 1 1 1 2 2 2 0 Cytochrome C' TPR_4 PF07721.14 EJP70035.1 - 0.2 12.4 7.6 7.1 7.6 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2207 PF09972.9 EJP70036.1 - 1.5 7.5 5.4 2.4 6.8 5.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) APC_u15 PF16636.5 EJP70036.1 - 1.9 9.0 18.8 0.14 12.6 5.8 3.0 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Xpo1 PF08389.12 EJP70037.1 - 5.3e-36 123.9 4.6 1.2e-35 122.7 0.2 3.5 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 EJP70037.1 - 0.0027 17.8 0.2 4.7 7.7 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat DUF4844 PF16133.5 EJP70037.1 - 0.046 14.3 0.4 6.3 7.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) CNOT11 PF10155.9 EJP70037.1 - 0.16 12.1 1.2 20 5.3 0.2 3.1 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Scm3 PF10384.9 EJP70037.1 - 0.26 11.1 0.9 5.5 6.8 0.0 3.0 3 0 0 3 3 3 0 Centromere protein Scm3 DUF1539 PF07560.11 EJP70037.1 - 0.46 10.6 3.3 14 5.8 0.0 4.6 5 1 1 6 6 6 0 Domain of Unknown Function (DUF1539) RTA1 PF04479.13 EJP70039.1 - 1.1e-64 217.9 15.5 1.1e-64 217.9 15.5 1.4 2 0 0 2 2 2 1 RTA1 like protein Peptidase_M18 PF02127.15 EJP70040.1 - 1.6e-164 547.9 0.0 5.3e-164 546.1 0.0 1.7 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EJP70040.1 - 0.0019 17.3 0.1 0.031 13.3 0.1 2.3 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Whi5 PF08528.11 EJP70041.1 - 8.7e-10 38.0 0.0 1.5e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Sporozoite_P67 PF05642.11 EJP70041.1 - 0.0027 15.9 5.7 0.0027 15.9 5.7 1.6 1 1 1 2 2 2 1 Sporozoite P67 surface antigen CBM_5_12 PF02839.14 EJP70044.1 - 0.14 12.8 0.4 0.14 12.8 0.4 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain SGL PF08450.12 EJP70045.1 - 1.4e-59 201.6 0.0 1.8e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Fea1 PF07692.11 EJP70045.1 - 0.062 12.3 0.0 0.088 11.8 0.0 1.1 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein Arylesterase PF01731.20 EJP70045.1 - 0.19 12.0 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 Arylesterase ATP-synt_DE_N PF02823.16 EJP70046.1 - 4.3e-19 68.2 0.0 6.4e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Fimbrial_PilY2 PF14481.6 EJP70046.1 - 0.067 12.8 0.1 0.91 9.2 0.0 2.1 1 1 1 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 DUF2457 PF10446.9 EJP70048.1 - 2.8e-164 547.7 38.5 2.8e-164 547.7 38.5 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) TFIIA PF03153.13 EJP70048.1 - 0.0041 17.2 19.3 0.0041 17.2 19.3 2.5 2 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EJP70048.1 - 8 4.6 28.9 1.8 6.7 16.4 2.2 2 0 0 2 2 2 0 CDC45-like protein Arf PF00025.21 EJP70049.1 - 4.1e-64 215.2 0.0 4.5e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EJP70049.1 - 2.6e-09 36.7 0.0 8.9e-06 25.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EJP70049.1 - 2.4e-07 30.4 0.0 3.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EJP70049.1 - 3.3e-07 30.4 0.0 4.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EJP70049.1 - 4.1e-07 30.2 0.0 1.3e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJP70049.1 - 7.5e-07 28.9 0.0 9.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EJP70049.1 - 6.5e-05 22.4 0.0 7.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EJP70049.1 - 0.012 15.1 0.1 0.34 10.4 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 EJP70049.1 - 0.13 11.8 0.0 9.7 5.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CENP-M PF11111.8 EJP70049.1 - 0.16 11.2 0.0 0.44 9.7 0.0 1.6 2 0 0 2 2 2 0 Centromere protein M (CENP-M) DUF3336 PF11815.8 EJP70050.1 - 7.8e-52 174.7 0.9 1.2e-51 174.1 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EJP70050.1 - 3.6e-15 56.7 0.3 3.6e-15 56.7 0.3 3.1 2 2 0 2 2 2 1 Patatin-like phospholipase DUF3833 PF12915.7 EJP70050.1 - 0.14 11.7 1.1 0.28 10.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) DnaJ PF00226.31 EJP70051.1 - 5.2e-15 55.3 4.6 6e-15 55.1 2.1 2.3 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.16 EJP70051.1 - 8.9e-09 34.9 0.0 2.3e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 Sec63 Brl domain DUF2347 PF09804.9 EJP70052.1 - 1.4e-104 349.7 0.0 1.8e-104 349.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EJP70052.1 - 9.3e-67 225.1 1.1 1.9e-66 224.1 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 EJP70052.1 - 0.00014 21.8 0.0 0.00038 20.4 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EJP70052.1 - 0.00028 19.7 0.0 0.0056 15.4 0.0 2.5 2 1 0 3 3 3 1 Transport protein Avl9 DUF4611 PF15387.6 EJP70052.1 - 0.13 12.5 0.5 0.54 10.5 0.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Acyltransferase PF01553.21 EJP70053.1 - 1.1e-31 109.2 0.0 1.6e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase MFS_1 PF07690.16 EJP70054.1 - 1.1e-30 106.7 49.8 5.2e-26 91.4 40.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.12 EJP70054.1 - 0.87 9.6 11.5 0.13 12.3 5.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) DUF4045 PF13254.6 EJP70055.1 - 3.7e-86 290.4 46.8 3.7e-86 290.4 46.8 6.7 3 2 0 3 3 3 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EJP70055.1 - 1.6e-08 34.3 0.0 0.0096 15.8 0.0 3.8 3 0 0 3 3 3 3 Gelsolin repeat Arf PF00025.21 EJP70056.1 - 5e-67 224.7 1.1 7.8e-67 224.1 1.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EJP70056.1 - 1.9e-11 44.2 0.5 5.3e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJP70056.1 - 2e-11 43.7 0.0 1.1e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Ras family G-alpha PF00503.20 EJP70056.1 - 3.2e-11 43.0 0.8 2.5e-06 26.9 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EJP70056.1 - 1.3e-08 34.5 0.0 2.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EJP70056.1 - 5.1e-08 32.6 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EJP70056.1 - 1.1e-07 32.0 0.0 1.2e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Acetyltransf_7 PF13508.7 EJP70056.1 - 0.00028 21.2 0.0 0.00071 20.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP70056.1 - 0.001 19.3 0.0 0.01 16.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family GTP_EFTU PF00009.27 EJP70056.1 - 0.017 14.7 0.0 0.62 9.6 0.0 2.9 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain zf_C2H2_ZHX PF18387.1 EJP70056.1 - 0.1 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain SCO1-SenC PF02630.14 EJP70058.1 - 0.057 13.3 0.8 10 6.1 0.1 2.6 2 0 0 2 2 2 0 SCO1/SenC DUF3584 PF12128.8 EJP70058.1 - 1.7 6.1 31.7 75 0.6 33.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3453 PF11935.8 EJP70059.1 - 2.5e-68 230.1 0.2 7.9e-68 228.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) HEAT_EZ PF13513.6 EJP70059.1 - 0.31 11.6 1.3 5.3 7.7 0.4 3.2 2 0 0 2 2 2 0 HEAT-like repeat Coiled-coil_56 PF09813.9 EJP70060.1 - 3e-06 27.2 0.0 3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 MFS_1 PF07690.16 EJP70061.1 - 9e-46 156.4 34.1 1.2e-45 156.0 34.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sds3 PF08598.11 EJP70061.1 - 1e-13 51.8 1.8 1e-13 51.8 1.8 2.3 2 1 0 2 2 2 1 Sds3-like Sugar_tr PF00083.24 EJP70061.1 - 6.6e-13 48.3 10.7 1.7e-12 47.0 10.7 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EJP70061.1 - 5e-06 25.1 4.1 5e-06 25.1 4.1 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 EJP70061.1 - 2.9e-05 22.7 3.9 4.7e-05 22.0 3.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EJP70064.1 - 3.1e-22 79.0 29.6 3.1e-22 79.0 29.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_2 PF00891.18 EJP70065.1 - 2.6e-23 82.4 0.0 7e-23 81.0 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EJP70065.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 EJP70065.1 - 0.0081 16.2 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain His_Phos_2 PF00328.22 EJP70066.1 - 9.2e-06 25.2 0.6 0.00029 20.3 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) adh_short_C2 PF13561.6 EJP70067.1 - 1.8e-40 138.9 0.8 2.4e-40 138.6 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP70067.1 - 2.3e-34 118.5 1.1 3e-34 118.2 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP70067.1 - 5.6e-13 49.2 0.2 7.9e-13 48.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP70067.1 - 0.036 13.5 0.5 0.073 12.5 0.1 1.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP70067.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pkinase PF00069.25 EJP70068.1 - 4.8e-67 226.1 0.0 8.7e-67 225.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70068.1 - 1.1e-35 123.1 0.0 2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJP70068.1 - 0.0002 21.4 0.0 0.00055 19.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP70068.1 - 0.00025 20.5 0.1 0.00074 18.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EJP70068.1 - 0.011 15.1 0.4 0.19 11.0 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EJP70068.1 - 0.023 13.5 0.0 0.048 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Prominin PF05478.11 EJP70068.1 - 0.033 12.2 1.1 0.061 11.3 1.1 1.3 1 0 0 1 1 1 0 Prominin Seadorna_VP7 PF07387.11 EJP70068.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FtsX_ECD PF18075.1 EJP70068.1 - 0.066 13.9 0.2 0.61 10.7 0.0 2.7 2 0 0 2 2 2 0 FtsX extracellular domain Mer2 PF09074.10 EJP70068.1 - 0.2 11.4 3.1 2.9 7.7 0.1 2.5 2 0 0 2 2 2 0 Mer2 EzrA PF06160.12 EJP70068.1 - 0.23 9.6 2.5 6.9 4.7 0.1 2.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA dCMP_cyt_deam_1 PF00383.23 EJP70069.1 - 1.4e-09 37.7 1.1 5e-08 32.7 1.1 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EJP70069.1 - 0.00066 19.3 1.9 0.13 11.9 0.1 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_2 PF08211.12 EJP70069.1 - 0.025 14.8 6.4 0.79 9.9 3.5 3.0 2 1 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Tantalus PF15386.6 EJP70070.1 - 0.43 10.7 1.8 6.3 7.0 0.0 3.1 3 0 0 3 3 3 0 Drosophila Tantalus-like MADF_DNA_bdg PF10545.9 EJP70071.1 - 0.037 14.3 1.7 0.92 9.9 0.1 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1993 PF09351.10 EJP70071.1 - 0.054 13.6 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) PBECR5 PF18814.1 EJP70071.1 - 0.09 12.7 0.3 0.15 12.0 0.3 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 HSP70 PF00012.20 EJP70072.1 - 0.067 11.4 0.0 1.1 7.4 0.0 2.2 2 1 0 2 2 2 0 Hsp70 protein WD40 PF00400.32 EJP70073.1 - 4.5e-54 179.2 11.9 7.2e-10 39.3 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP70073.1 - 3e-20 72.3 0.0 0.0034 17.7 0.0 6.7 3 3 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP70073.1 - 1e-08 34.5 0.2 0.035 13.1 0.0 4.8 3 3 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EJP70073.1 - 3.1e-05 23.9 0.0 0.0017 18.2 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EJP70073.1 - 3.4e-05 22.7 0.3 0.82 8.2 0.0 3.7 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 EJP70073.1 - 0.0092 15.9 0.4 47 4.1 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 EJP70073.1 - 0.023 13.8 0.0 1.7 7.6 0.0 3.4 4 1 1 5 5 5 0 VID27 C-terminal WD40-like domain Frtz PF11768.8 EJP70073.1 - 0.084 11.2 0.0 0.71 8.1 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 EJP70073.1 - 0.13 11.6 1.0 5.1 6.3 0.0 3.5 3 1 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Ndc1_Nup PF09531.10 EJP70073.1 - 5.1 5.7 9.0 7.1 5.2 9.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIF_alpha PF05793.12 EJP70073.1 - 6.1 5.3 15.4 8.5 4.8 15.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GPI-anchored PF10342.9 EJP70074.1 - 1.3e-19 70.7 0.3 1.3e-19 70.7 0.3 3.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAP1 PF08601.10 EJP70074.1 - 0.0036 17.1 17.4 0.0044 16.8 17.4 1.2 1 0 0 1 1 1 1 Transcription factor PAP1 GREB1 PF15782.5 EJP70074.1 - 0.13 9.4 8.2 0.16 9.1 8.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Miff PF05644.11 EJP70074.1 - 0.31 10.6 2.9 0.37 10.4 2.9 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Macoilin PF09726.9 EJP70074.1 - 5.6 5.4 12.2 6.7 5.1 12.2 1.1 1 0 0 1 1 1 0 Macoilin family Tmemb_cc2 PF10267.9 EJP70074.1 - 8.9 5.3 7.8 12 4.9 7.8 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MFS_1 PF07690.16 EJP70075.1 - 1.1e-26 93.7 21.0 1.4e-26 93.3 21.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily THF_DHG_CYH PF00763.23 EJP70076.1 - 4.4e-24 85.0 0.2 6.7e-24 84.4 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EJP70076.1 - 5.7e-14 51.7 0.0 1.3e-08 34.4 0.0 2.8 3 0 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Apq12 PF12716.7 EJP70078.1 - 1.9e-10 40.5 14.2 3.3e-10 39.8 14.2 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.17 EJP70079.1 - 5.7e-72 242.4 0.0 1.1e-71 241.4 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EJP70079.1 - 0.00075 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EJP70079.1 - 0.0021 18.1 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJP70079.1 - 0.007 16.9 0.1 0.039 14.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EJP70079.1 - 0.0074 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 EJP70079.1 - 0.0083 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 EJP70079.1 - 0.0085 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJP70079.1 - 0.013 15.7 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EJP70079.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EJP70079.1 - 0.024 14.5 0.1 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CbiA PF01656.23 EJP70079.1 - 0.034 14.2 0.0 0.038 14.0 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 EJP70079.1 - 0.038 14.5 0.0 0.078 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.7 EJP70079.1 - 0.071 12.0 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain GTP_EFTU PF00009.27 EJP70079.1 - 0.072 12.6 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EJP70079.1 - 0.095 13.1 0.3 0.52 10.7 0.0 2.2 2 1 1 3 3 3 0 AAA ATPase domain Cytidylate_kin PF02224.18 EJP70079.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase SRP54 PF00448.22 EJP70079.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EJP70079.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase S-AdoMet_synt_C PF02773.16 EJP70080.1 - 2.2e-66 222.0 0.4 4.7e-66 221.0 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EJP70080.1 - 8.6e-45 151.9 0.0 1.8e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EJP70080.1 - 7.5e-44 148.4 0.5 1.6e-43 147.4 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EJP70080.1 - 0.038 12.8 0.3 0.41 9.4 0.1 2.1 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) PI-PLC-X PF00388.19 EJP70081.1 - 3.4e-10 39.7 0.0 5.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MaoC_dehydratas PF01575.19 EJP70083.1 - 1.7e-22 79.3 0.0 4.4e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EJP70083.1 - 1.1e-08 35.3 0.0 3.4e-06 27.2 0.0 2.6 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase LRR_8 PF13855.6 EJP70084.1 - 2.1e-12 46.6 2.4 0.00032 20.4 2.1 3.8 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EJP70084.1 - 3.3e-11 43.2 9.7 0.0018 18.6 3.2 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) CAP_GLY PF01302.25 EJP70084.1 - 1.5e-10 40.9 0.1 3e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_6 PF13516.6 EJP70084.1 - 1.1e-08 34.4 1.0 1.7 8.9 0.5 6.2 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 EJP70084.1 - 7.8e-05 22.3 1.1 0.042 13.3 0.1 3.4 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 EJP70084.1 - 0.1 13.2 8.4 44 5.2 0.1 5.6 5 2 1 6 6 6 0 Leucine Rich Repeat CENP-B_dimeris PF09026.10 EJP70084.1 - 0.4 11.1 5.5 0.96 9.9 5.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-CCCH PF00642.24 EJP70085.1 - 9.3e-09 35.0 19.2 3.3e-07 30.0 2.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EJP70085.1 - 0.00019 21.2 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EJP70085.1 - 0.012 15.6 2.9 0.012 15.6 2.9 3.3 3 0 0 3 3 3 0 Zinc finger domain Torus PF16131.5 EJP70085.1 - 0.036 14.8 6.6 0.33 11.7 0.8 2.7 2 1 0 3 3 3 0 Torus domain SCRG1 PF15224.6 EJP70085.1 - 0.49 10.5 0.1 0.49 10.5 0.1 2.4 2 1 0 2 2 2 0 Scrapie-responsive protein 1 zf-CCCH_3 PF15663.5 EJP70085.1 - 0.55 10.5 6.1 0.35 11.1 1.3 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Oxysterol_BP PF01237.18 EJP70086.1 - 4.5e-86 289.0 0.8 1.7e-83 280.5 0.8 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Dus PF01207.17 EJP70088.1 - 4.9e-42 144.1 0.3 2.1e-41 142.0 0.3 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ApoO PF09769.9 EJP70089.1 - 5.1e-41 139.7 0.1 1.3e-40 138.4 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O Na_H_antiporter PF03553.14 EJP70089.1 - 0.074 12.3 0.2 2.6 7.2 0.5 2.2 1 1 1 2 2 2 0 Na+/H+ antiporter family Ferric_reduct PF01794.19 EJP70090.1 - 3.1e-21 75.8 16.7 9.2e-21 74.3 16.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EJP70090.1 - 3.8e-05 23.7 0.0 0.00033 20.7 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 EJP70090.1 - 9.2e-05 22.6 0.1 0.24 11.5 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EJP70090.1 - 0.003 18.2 0.0 0.0053 17.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Peptidase_M3 PF01432.20 EJP70091.1 - 8.5e-119 397.8 0.0 1.6e-118 396.9 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 EJP70091.1 - 0.057 13.1 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like NOA36 PF06524.12 EJP70092.1 - 0.25 10.6 6.6 0.42 9.9 6.6 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EJP70092.1 - 0.75 9.5 11.1 0.13 12.0 7.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EJP70092.1 - 4.4 7.8 13.0 12 6.3 13.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EJP70092.1 - 4.5 6.9 7.8 0.25 11.0 1.4 2.2 2 0 0 2 2 2 0 FAM176 family FAD_binding_3 PF01494.19 EJP70093.1 - 2e-37 129.2 0.0 5.2e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EJP70093.1 - 1.9e-05 24.1 0.5 3.3e-05 23.3 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP70093.1 - 0.0011 18.1 0.2 0.0028 16.8 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EJP70093.1 - 0.0022 17.1 0.2 0.33 9.9 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 EJP70093.1 - 0.0036 16.6 0.1 0.006 15.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EJP70093.1 - 0.012 15.9 0.1 0.032 14.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EJP70093.1 - 0.018 13.8 0.1 0.027 13.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 EJP70093.1 - 0.059 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP70093.1 - 0.11 12.1 0.4 0.25 10.9 0.4 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase AMP-binding PF00501.28 EJP70094.1 - 1.1e-60 205.4 0.0 1.7e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EJP70094.1 - 3.2e-11 42.6 0.1 4.9e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Condensation domain AMP-binding_C PF13193.6 EJP70094.1 - 4.8e-11 43.5 0.1 1.3e-10 42.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 EJP70094.1 - 0.0045 17.3 0.1 0.018 15.4 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site p450 PF00067.22 EJP70096.1 - 1.1e-47 162.8 0.0 1.5e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EJP70097.1 - 1.2e-11 44.7 0.0 2.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP70097.1 - 5.4e-06 26.3 0.0 8.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PDZ_6 PF17820.1 EJP70097.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 PDZ domain ketoacyl-synt PF00109.26 EJP70098.1 - 2.1e-71 240.5 0.0 4.8e-71 239.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EJP70098.1 - 6.6e-47 159.7 1.1 1.7e-46 158.4 0.2 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EJP70098.1 - 1.1e-46 159.9 0.1 2.5e-46 158.7 0.1 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EJP70098.1 - 7.2e-43 146.9 0.0 1.2e-42 146.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EJP70098.1 - 1.3e-31 109.1 0.0 3e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EJP70098.1 - 1.6e-13 51.1 0.1 9.5e-13 48.6 0.1 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EJP70098.1 - 2.2e-07 30.5 0.0 4.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 EJP70098.1 - 9e-07 29.2 1.0 3.5e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EJP70098.1 - 3.1e-06 26.7 0.1 6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 EJP70098.1 - 0.00015 21.4 0.1 0.00015 21.4 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 EJP70098.1 - 0.17 11.7 0.0 0.7 9.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain AAA_11 PF13086.6 EJP70100.1 - 4.4e-60 203.7 0.1 4.3e-59 200.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EJP70100.1 - 1.7e-54 184.5 0.0 3.2e-54 183.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP70100.1 - 1.3e-11 44.6 0.0 2.1e-10 40.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP70100.1 - 3.9e-08 33.7 0.0 1.3e-07 32.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 EJP70100.1 - 7.8e-07 29.2 0.0 2.5e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EJP70100.1 - 1.2e-06 28.0 0.0 7.4e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EJP70100.1 - 8e-06 25.8 0.0 0.7 9.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EJP70100.1 - 5.9e-05 23.4 0.3 0.0027 18.0 0.3 2.7 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EJP70100.1 - 8.3e-05 22.2 0.0 0.00029 20.5 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EJP70100.1 - 0.0014 19.0 0.1 0.0042 17.5 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 EJP70100.1 - 0.0015 18.4 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 EJP70100.1 - 0.0018 17.4 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 EJP70100.1 - 0.0043 16.7 0.7 0.52 9.8 0.0 3.5 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EJP70100.1 - 0.014 15.1 0.0 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EJP70100.1 - 0.027 13.9 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Flavi_DEAD PF07652.14 EJP70100.1 - 0.028 14.4 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_24 PF13479.6 EJP70100.1 - 0.031 14.0 0.0 0.14 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain UvrD_C PF13361.6 EJP70100.1 - 0.037 13.4 0.3 1.9 7.8 0.0 2.8 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.29 EJP70100.1 - 0.041 14.3 1.2 0.16 12.4 0.5 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EJP70100.1 - 0.048 14.2 0.0 0.17 12.4 0.0 2.1 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EJP70100.1 - 0.055 13.5 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EJP70100.1 - 0.12 12.3 0.5 7.2 6.5 0.0 2.6 2 0 0 2 2 2 0 NTPase 4HB_MCP_1 PF12729.7 EJP70100.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ATPase_2 PF01637.18 EJP70100.1 - 0.15 11.9 0.3 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Diphthami_syn_2 PF01902.17 EJP70101.1 - 1.2e-24 87.0 0.0 9.2e-24 84.2 0.0 2.3 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EJP70101.1 - 3.9e-10 39.8 0.0 0.00049 20.1 0.0 3.4 3 0 0 3 3 3 3 Endoribonuclease L-PSP zf-C2H2 PF00096.26 EJP70102.1 - 5e-13 48.7 11.0 1.6e-06 28.2 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP70102.1 - 4.6e-09 36.3 11.1 1.7e-07 31.4 4.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP70102.1 - 3.2e-08 33.7 10.0 0.0014 19.3 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EJP70102.1 - 7e-07 29.4 3.9 0.00025 21.3 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EJP70102.1 - 4.2e-06 26.9 4.6 0.003 17.8 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EJP70102.1 - 9e-06 25.6 8.3 0.0036 17.3 0.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EJP70102.1 - 0.0059 16.2 3.2 0.62 9.8 0.2 2.4 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 EJP70102.1 - 0.024 14.6 1.5 0.024 14.6 1.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf_UBZ PF18439.1 EJP70102.1 - 0.041 13.5 1.6 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 EJP70102.1 - 0.14 12.8 1.6 4.5 8.0 0.2 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 EJP70102.1 - 0.33 10.8 5.4 7.4 6.4 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Actin_micro PF17003.5 EJP70102.1 - 0.9 8.7 2.2 4.3 6.4 2.3 1.8 1 1 0 1 1 1 0 Putative actin-like family Zn-ribbon_8 PF09723.10 EJP70102.1 - 1.5 9.0 4.9 8.1 6.7 0.6 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 EJP70102.1 - 6.3 7.3 7.1 68 4.0 7.1 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 EJP70102.1 - 8 6.5 7.4 9.8 6.2 2.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type NmrA PF05368.13 EJP70103.1 - 8.3e-20 71.3 0.0 1e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP70103.1 - 8.7e-07 29.0 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EJP70103.1 - 0.052 13.4 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 KR domain ADK PF00406.22 EJP70104.1 - 1.3e-44 151.9 0.0 1.8e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EJP70104.1 - 3.8e-35 121.3 0.0 2.2e-34 118.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EJP70104.1 - 1.6e-07 31.9 0.0 2.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EJP70104.1 - 1.7e-05 25.0 0.8 0.00024 21.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EJP70104.1 - 0.0016 18.2 0.1 0.43 10.2 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase Glyco_hydro_16 PF00722.21 EJP70105.1 - 1.2e-42 145.3 0.5 1.8e-42 144.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I PF01028.20 EJP70106.1 - 6.6e-98 326.6 5.3 1.8e-97 325.1 5.3 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EJP70106.1 - 8.1e-92 306.5 5.2 8.1e-92 306.5 5.2 3.7 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EJP70106.1 - 3.3e-31 107.0 0.4 1e-30 105.4 0.4 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.19 EJP70107.1 - 3.3e-79 266.5 4.5 4e-79 266.3 4.5 1.0 1 0 0 1 1 1 1 ATP synthase DUF1480 PF07351.13 EJP70107.1 - 0.13 12.5 0.0 10 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1480) Amino_oxidase PF01593.24 EJP70108.1 - 6.1e-83 279.6 0.0 5.3e-71 240.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 EJP70108.1 - 9.2e-12 45.1 0.1 2e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 EJP70108.1 - 1e-08 35.3 0.0 3e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 EJP70108.1 - 3.9e-06 27.4 2.8 1.2e-05 25.8 2.8 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EJP70108.1 - 3.2e-05 24.3 4.0 3.2e-05 24.3 4.0 2.2 2 1 0 2 2 2 1 HMG (high mobility group) box Pyr_redox_2 PF07992.14 EJP70108.1 - 0.00072 18.9 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP70108.1 - 0.0019 17.8 0.1 0.004 16.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EJP70108.1 - 0.16 11.9 0.0 0.78 9.7 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sec1 PF00995.23 EJP70109.1 - 1.2e-127 427.6 0.0 1.3e-127 427.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UQ_con PF00179.26 EJP70110.1 - 2.4e-25 88.8 0.0 3e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP70110.1 - 0.00043 20.0 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EJP70110.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.25 EJP70111.1 - 3.1e-69 233.3 0.0 4e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70111.1 - 1.3e-34 119.7 0.0 2e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP70111.1 - 7.8e-07 28.7 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJP70111.1 - 0.00079 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EJP70111.1 - 0.01 15.4 0.2 0.033 13.7 0.1 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL G2BR PF18442.1 EJP70111.1 - 0.05 13.2 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Med11 PF10280.9 EJP70112.1 - 0.041 14.4 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 Mediator complex protein tRNA-synt_His PF13393.6 EJP70113.1 - 1.8e-38 132.6 0.0 4.7e-32 111.5 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EJP70113.1 - 2.9e-12 46.6 0.0 5.4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EJP70113.1 - 0.00065 19.3 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 EJP70113.1 - 0.0041 17.1 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EJP70113.1 - 0.013 14.6 0.0 0.056 12.5 0.0 2.1 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Abhydrolase_1 PF00561.20 EJP70114.1 - 2.6e-15 56.8 0.6 7.3e-15 55.3 0.2 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP70114.1 - 1.2e-13 51.0 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP70114.1 - 1.1e-09 39.3 0.6 1.7e-09 38.7 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EJP70114.1 - 0.02 14.8 0.1 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DLH PF01738.18 EJP70114.1 - 0.033 13.7 0.0 0.58 9.7 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF676 PF05057.14 EJP70114.1 - 0.056 12.9 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_2 PF01674.18 EJP70114.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_5 PF12695.7 EJP70114.1 - 0.17 11.7 0.1 3.9 7.2 0.1 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase family zf-C2H2 PF00096.26 EJP70115.1 - 4.8e-12 45.6 6.1 1.2e-05 25.5 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 EJP70115.1 - 1.8e-11 43.6 0.3 3.1e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 EJP70115.1 - 1.4e-07 31.8 13.0 0.00029 21.4 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.18 EJP70115.1 - 4.9e-06 26.6 10.5 1.3e-05 25.3 10.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 EJP70115.1 - 0.0024 18.2 3.5 0.59 10.7 0.4 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 EJP70115.1 - 0.0073 16.7 2.4 0.12 12.8 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EJP70115.1 - 0.0089 16.3 1.1 0.14 12.5 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.16 EJP70116.1 - 2.9e-31 108.7 27.8 2.9e-31 108.7 27.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP70116.1 - 3e-18 65.9 9.5 3e-18 65.9 9.5 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter FYVE PF01363.21 EJP70117.1 - 1.1e-20 73.5 1.5 1.1e-20 73.5 1.5 2.8 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EJP70117.1 - 6e-07 29.7 23.2 8.9e-07 29.1 3.9 3.4 3 0 0 3 3 3 2 Ring finger domain zf-RING_11 PF17123.5 EJP70117.1 - 0.00031 20.4 3.9 0.00031 20.4 3.9 2.6 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EJP70117.1 - 0.00042 20.1 3.4 0.00042 20.1 3.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EJP70117.1 - 0.0078 16.0 1.5 0.021 14.7 0.2 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_UBOX PF13445.6 EJP70117.1 - 0.01 15.8 4.3 0.01 15.8 4.3 3.5 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING-like PF08746.11 EJP70117.1 - 0.015 15.5 2.0 0.015 15.5 2.0 2.6 3 0 0 3 3 2 0 RING-like domain Elf1 PF05129.13 EJP70117.1 - 0.018 15.0 6.3 0.038 14.0 0.8 3.0 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.7 EJP70117.1 - 0.32 11.0 8.6 4.5 7.4 4.1 2.9 2 0 0 2 2 2 0 Double zinc ribbon zf-piccolo PF05715.13 EJP70117.1 - 0.36 11.0 15.3 0.095 12.9 5.6 3.0 3 0 0 3 3 3 0 Piccolo Zn-finger FYVE_2 PF02318.16 EJP70117.1 - 0.45 10.7 9.6 0.11 12.7 2.0 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger C2 PF00168.30 EJP70118.1 - 9.5e-89 292.5 0.1 5.9e-24 84.3 0.0 5.4 5 0 0 5 5 5 5 C2 domain Proteasome PF00227.26 EJP70119.1 - 8e-46 155.9 0.1 9.9e-46 155.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M22 PF00814.25 EJP70120.1 - 1.1e-42 146.7 0.2 2e-38 132.7 0.2 3.2 1 1 0 1 1 1 1 Glycoprotease family Glyco_transf_34 PF05637.12 EJP70122.1 - 3e-67 226.8 0.2 4e-67 226.4 0.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family E2 PF08199.11 EJP70122.1 - 0.3 11.1 3.9 0.62 10.0 3.9 1.5 1 0 0 1 1 1 0 Bacteriophage E2-like protein Glyco_hydro_16 PF00722.21 EJP70123.1 - 4.3e-08 32.8 0.5 1e-07 31.6 0.1 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 RNA_pol_Rpb1_1 PF04997.12 EJP70124.1 - 1.5e-82 277.5 0.2 2.3e-82 276.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EJP70124.1 - 1e-76 257.9 0.3 1.8e-76 257.1 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EJP70124.1 - 4.3e-72 241.7 0.0 7.8e-72 240.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EJP70124.1 - 6.1e-35 120.5 0.0 1.1e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EJP70124.1 - 9.6e-30 102.7 0.0 2.7e-29 101.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TFIID_30kDa PF03540.13 EJP70124.1 - 0.05 13.5 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit zf-ribbon_3 PF13248.6 EJP70124.1 - 0.15 11.5 2.8 2.5 7.6 0.9 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S14 PF00253.21 EJP70124.1 - 0.24 11.2 2.7 1.1 9.1 0.7 2.6 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e MAPEG PF01124.18 EJP70125.1 - 2.2e-17 63.2 1.1 2.5e-17 63.0 1.1 1.0 1 0 0 1 1 1 1 MAPEG family MFS_2 PF13347.6 EJP70126.1 - 2.9e-10 39.3 11.2 1.3e-09 37.2 4.6 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein Phage_holin_2_4 PF16082.5 EJP70126.1 - 3.3 7.5 7.7 8.8 6.1 0.3 3.9 4 0 0 4 4 4 0 Bacteriophage holin family, superfamily II-like Pkinase PF00069.25 EJP70127.1 - 2.2e-56 191.2 0.0 3.1e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70127.1 - 2.8e-31 108.7 0.0 8.4e-30 103.9 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EJP70127.1 - 0.0067 15.5 0.0 0.0094 15.0 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 EJP70127.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EJP70127.1 - 0.09 12.1 0.8 0.16 11.3 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJP70127.1 - 0.23 10.7 0.3 3.1 7.0 0.1 2.1 2 0 0 2 2 2 0 Kinase-like HSP70 PF00012.20 EJP70128.1 - 6.6e-10 37.8 0.1 4.4e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 EJP70128.1 - 0.00035 21.0 0.0 0.055 13.9 0.0 2.5 2 0 0 2 2 2 2 Cell division protein FtsA SARAF PF06682.12 EJP70128.1 - 0.034 13.8 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SET PF00856.28 EJP70129.1 - 1.9e-07 31.6 0.0 4.8e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 SET domain ArAE_2_N PF10337.9 EJP70130.1 - 6.6e-87 292.5 1.1 1.3e-86 291.5 1.1 1.5 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EJP70130.1 - 8.1e-47 160.0 0.0 7.8e-46 156.7 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EJP70130.1 - 1.3e-05 25.3 19.0 1.3e-05 25.3 19.0 4.4 3 2 1 4 4 4 1 Fusaric acid resistance protein-like DUF2513 PF10711.9 EJP70130.1 - 0.043 14.1 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) FAD_binding_2 PF00890.24 EJP70133.1 - 6e-123 411.0 5.0 7.6e-123 410.7 5.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EJP70133.1 - 5.3e-44 149.3 0.4 8e-44 148.7 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EJP70133.1 - 2.7e-06 26.8 0.9 0.003 16.8 0.4 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP70133.1 - 0.00011 21.5 0.1 0.12 11.6 0.1 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EJP70133.1 - 0.00012 21.4 1.0 0.045 12.8 1.9 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EJP70133.1 - 0.003 16.8 0.1 0.003 16.8 0.1 2.3 3 0 0 3 3 3 1 FAD binding domain DUF600 PF04634.12 EJP70133.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF600 DAO PF01266.24 EJP70133.1 - 0.2 11.2 2.4 0.27 10.8 1.5 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EJP70133.1 - 0.76 8.4 2.7 0.97 8.1 0.3 2.2 3 0 0 3 3 3 0 HI0933-like protein Peptidase_S8 PF00082.22 EJP70134.1 - 7.5e-42 143.6 4.9 1.3e-41 142.8 4.9 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EJP70134.1 - 1.7e-11 44.8 0.1 3.1e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 EJP70134.1 - 0.00014 21.7 1.1 0.0013 18.6 0.1 2.7 2 0 0 2 2 2 1 FlgD Ig-like domain NUDIX PF00293.28 EJP70135.1 - 1.9e-05 24.7 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EJP70135.1 - 0.00037 20.4 0.0 0.0006 19.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) Bromodomain PF00439.25 EJP70136.1 - 6e-27 93.5 0.0 9.3e-15 54.5 0.0 2.8 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 EJP70136.1 - 1.3e-15 57.3 0.5 3.3e-15 56.0 0.5 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF1690 PF07956.11 EJP70136.1 - 0.1 13.1 0.6 0.39 11.1 0.6 2.0 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Utp12 PF04003.12 EJP70137.1 - 9e-24 83.9 0.6 1.5e-23 83.2 0.1 1.6 2 0 0 2 2 2 1 Dip2/Utp12 Family SDA1 PF05285.12 EJP70137.1 - 8 5.8 33.7 2.7 7.3 24.2 2.1 2 0 0 2 2 2 0 SDA1 PRP4 PF08799.11 EJP70139.1 - 0.32 10.6 4.4 3.1 7.4 0.2 3.5 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like AA_permease PF00324.21 EJP70140.1 - 3.8e-101 339.1 40.4 4.3e-101 338.9 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP70140.1 - 2.2e-26 92.7 41.8 2.8e-26 92.3 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease ketoacyl-synt PF00109.26 EJP70141.1 - 3.2e-70 236.6 0.0 6.4e-70 235.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EJP70141.1 - 6.2e-65 218.5 0.5 1.9e-64 216.9 0.2 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EJP70141.1 - 6.9e-55 186.8 0.7 2.6e-54 184.9 0.1 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EJP70141.1 - 2e-37 127.8 0.0 1e-36 125.5 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EJP70141.1 - 3e-36 125.2 0.0 4.9e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EJP70141.1 - 6.4e-20 71.7 0.0 2e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EJP70141.1 - 3.4e-19 69.1 1.2 3.8e-18 65.7 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EJP70141.1 - 9.3e-18 65.6 0.0 3.5e-17 63.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EJP70141.1 - 2.6e-17 63.0 0.0 1.8e-16 60.3 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 EJP70141.1 - 2.8e-11 43.4 0.0 6.8e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 EJP70141.1 - 1.4e-07 31.4 0.6 6.2e-07 29.3 0.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 EJP70141.1 - 2.5e-05 23.6 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EJP70141.1 - 0.00012 21.6 0.0 0.00033 20.2 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 EJP70141.1 - 0.00014 21.3 0.1 0.00037 19.9 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EJP70141.1 - 0.00016 22.0 0.1 0.00039 20.7 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 EJP70141.1 - 0.0056 16.5 0.5 0.016 15.0 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GDP_Man_Dehyd PF16363.5 EJP70141.1 - 0.0077 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_3 PF03447.16 EJP70141.1 - 0.022 15.4 0.0 0.069 13.8 0.0 1.9 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain FSH1 PF03959.13 EJP70142.1 - 3.4e-27 95.5 0.0 1.1e-26 93.8 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) UDPGT PF00201.18 EJP70143.1 - 8.5e-08 31.4 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EJP70143.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_hydro_125 PF06824.11 EJP70144.1 - 6.9e-138 460.0 0.1 2e-81 274.1 0.0 2.1 1 1 1 2 2 2 2 Metal-independent alpha-mannosidase (GH125) Fungal_trans PF04082.18 EJP70145.1 - 1.2e-08 34.4 0.1 1.8e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EJP70146.1 - 3.9e-33 114.8 26.8 3.9e-33 114.8 26.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribonuclease PF00545.20 EJP70147.1 - 1.4e-10 41.7 0.2 4.1e-10 40.3 0.0 1.7 1 1 1 2 2 2 1 ribonuclease Glyco_transf_54 PF04666.13 EJP70148.1 - 3.6e-13 49.0 0.0 1.6e-06 27.2 0.0 3.0 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF2754 PF10953.8 EJP70148.1 - 0.024 14.9 0.5 0.074 13.3 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) RSN1_TM PF13967.6 EJP70148.1 - 0.33 10.7 2.4 0.46 10.2 1.3 1.8 1 1 1 2 2 2 0 Late exocytosis, associated with Golgi transport Tmemb_170 PF10190.9 EJP70148.1 - 0.44 10.9 4.0 2.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Putative transmembrane protein 170 Phage_holin_3_6 PF07332.11 EJP70148.1 - 1.9 8.5 6.4 0.66 10.0 0.1 2.7 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DPBB_1 PF03330.18 EJP70149.1 - 3.9e-07 30.2 0.2 6.7e-07 29.5 0.2 1.4 1 1 0 1 1 1 1 Lytic transglycolase NiFe_hyd_SSU_C PF14720.6 EJP70149.1 - 0.064 13.6 0.0 0.092 13.1 0.0 1.3 1 0 0 1 1 1 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Cnn_1N PF07989.11 EJP70150.1 - 2.3e-08 34.1 6.5 2.3e-08 34.1 6.5 2.1 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Malate_DH PF12434.8 EJP70150.1 - 0.053 13.6 0.1 0.24 11.4 0.1 2.2 1 0 0 1 1 1 0 Malate dehydrogenase enzyme SKA1 PF07160.12 EJP70150.1 - 1.9 8.3 7.9 0.15 11.9 2.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 PRKCSH PF07915.13 EJP70151.1 - 1.1e-16 61.6 1.9 2.3e-16 60.6 0.0 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Methyltr_RsmB-F PF01189.17 EJP70152.1 - 3.4e-15 56.2 0.0 3e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F SDA1 PF05285.12 EJP70152.1 - 9.7 5.5 29.5 1.4 8.3 23.2 2.1 2 0 0 2 2 2 0 SDA1 DUF1996 PF09362.10 EJP70153.1 - 9.5e-64 215.6 0.2 1.5e-63 214.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EJP70153.1 - 5.3e-17 61.8 11.4 1.8e-16 60.1 11.4 2.0 1 0 0 1 1 1 1 WSC domain Velvet PF11754.8 EJP70154.1 - 8.7e-54 183.1 0.1 5.5e-32 111.7 0.0 2.1 1 1 1 2 2 2 2 Velvet factor SUZ PF12752.7 EJP70155.1 - 0.17 12.7 2.1 0.37 11.6 2.1 1.6 1 0 0 1 1 1 0 SUZ domain BES1_N PF05687.13 EJP70155.1 - 0.4 11.1 3.9 0.81 10.1 3.9 1.5 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal SPX PF03105.19 EJP70155.1 - 0.49 10.3 4.7 0.6 10.0 4.7 1.1 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 EJP70155.1 - 1.4 8.5 17.8 2.5 7.6 17.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EJP70155.1 - 1.4 6.9 14.4 1.8 6.5 14.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ABC_membrane PF00664.23 EJP70156.1 - 3.5e-105 351.6 36.7 5.9e-54 183.6 11.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP70156.1 - 2.8e-65 219.0 0.0 1.6e-31 109.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP70156.1 - 5.8e-14 52.1 0.0 3.3e-05 23.4 0.0 3.9 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP70156.1 - 3.4e-07 29.9 0.7 0.0029 17.3 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EJP70156.1 - 2.3e-06 26.7 3.1 0.0089 14.9 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EJP70156.1 - 3.2e-06 27.2 0.0 0.11 12.4 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EJP70156.1 - 2.3e-05 24.7 2.4 0.12 12.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJP70156.1 - 3.4e-05 24.3 3.4 0.12 12.8 0.2 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EJP70156.1 - 7.8e-05 23.1 1.3 0.86 10.0 0.1 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EJP70156.1 - 0.00013 21.6 0.1 0.21 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EJP70156.1 - 0.002 18.0 1.4 2 8.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EJP70156.1 - 0.0026 18.0 2.0 3.4 8.0 0.2 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EJP70156.1 - 0.0028 17.4 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 EJP70156.1 - 0.0041 16.6 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EJP70156.1 - 0.0043 17.3 0.6 0.38 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EJP70156.1 - 0.0051 16.8 1.7 13 5.8 0.0 4.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EJP70156.1 - 0.0072 16.1 2.6 6.3 6.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain G-alpha PF00503.20 EJP70156.1 - 0.012 14.9 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 EJP70156.1 - 0.016 15.7 0.0 6.5 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EJP70156.1 - 0.022 14.8 0.6 11 6.1 0.3 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 EJP70156.1 - 0.03 13.6 0.0 4.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EJP70156.1 - 0.031 14.4 0.0 14 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EJP70156.1 - 0.083 12.8 0.1 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain PRK PF00485.18 EJP70156.1 - 0.1 12.3 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EJP70156.1 - 0.11 12.2 0.1 8.8 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EJP70156.1 - 6.1 7.3 6.8 56 4.1 0.1 3.9 4 0 0 4 4 3 0 AAA domain SGL PF08450.12 EJP70157.1 - 0.035 13.7 0.0 0.18 11.4 0.0 2.0 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region SARAF PF06682.12 EJP70158.1 - 1.1e-104 350.7 4.8 1.3e-104 350.4 4.8 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis BRE1 PF08647.11 EJP70159.1 - 4.2e-27 94.1 7.3 4.2e-27 94.1 7.3 6.6 5 1 1 6 6 6 2 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.25 EJP70159.1 - 1.3e-08 34.6 10.3 2.2e-08 33.8 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJP70159.1 - 1.7e-08 34.2 7.4 2.6e-08 33.6 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJP70159.1 - 3.7e-08 33.1 7.2 6.2e-08 32.4 7.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EJP70159.1 - 2.4e-07 30.6 5.8 4.7e-07 29.7 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EJP70159.1 - 3.4e-07 30.0 8.5 5.8e-07 29.2 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP70159.1 - 1.4e-06 28.1 9.5 2.3e-06 27.5 9.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EJP70159.1 - 4.3e-06 26.9 8.4 7.1e-06 26.3 8.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EJP70159.1 - 0.011 15.8 6.9 0.022 14.9 6.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING JIP_LZII PF16471.5 EJP70159.1 - 0.017 15.3 2.7 0.017 15.3 2.7 7.5 6 2 2 8 8 8 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 EJP70159.1 - 0.024 14.7 1.9 0.024 14.7 1.9 9.4 5 3 5 11 11 11 0 bZIP transcription factor zf-RING_6 PF14835.6 EJP70159.1 - 0.028 14.3 3.1 0.06 13.2 3.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EJP70159.1 - 0.13 12.0 6.6 0.56 10.0 6.9 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EJP70159.1 - 0.27 11.0 4.6 0.65 9.8 4.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 EJP70159.1 - 0.34 11.2 7.8 5.4 7.4 7.8 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain kleA_kleC PF17383.2 EJP70159.1 - 0.64 10.4 0.0 0.64 10.4 0.0 5.5 3 2 3 6 6 6 0 Uncharacterized KorC regulated protein A DUF2935 PF11155.8 EJP70159.1 - 1.5 9.2 7.1 39 4.6 1.2 4.4 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) FYVE PF01363.21 EJP70159.1 - 1.6 8.9 11.5 14 5.9 11.3 2.3 1 1 1 2 2 2 0 FYVE zinc finger TSC22 PF01166.18 EJP70159.1 - 3.4 8.1 28.2 1.6 9.1 1.2 7.4 5 2 2 7 7 7 0 TSC-22/dip/bun family GIT_CC PF16559.5 EJP70159.1 - 7.7 6.5 21.2 3 7.8 0.6 5.7 6 0 0 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor Myb_DNA-bind_7 PF15963.5 EJP70160.1 - 1.3e-23 82.7 0.1 1.3e-23 82.7 0.1 2.1 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EJP70160.1 - 0.00015 21.9 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain UBA PF00627.31 EJP70161.1 - 4e-26 90.5 6.8 1.3e-13 50.5 0.5 2.8 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 EJP70161.1 - 1.1e-25 89.2 12.9 2.3e-25 88.1 12.9 1.6 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 EJP70161.1 - 4.4e-17 61.6 0.1 1.4e-09 37.6 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EJP70161.1 - 0.00062 19.5 0.1 0.023 14.5 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EJP70161.1 - 0.0032 17.3 0.0 3.5 7.5 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Clathrin_H_link PF13838.6 EJP70161.1 - 0.013 15.4 0.2 0.013 15.4 0.2 3.2 2 1 1 3 3 3 0 Clathrin-H-link WIYLD PF10440.9 EJP70161.1 - 0.023 14.5 0.5 0.31 10.9 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Ubiquitin_2 PF14560.6 EJP70161.1 - 0.1 13.1 0.0 0.31 11.5 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain MCM_N PF14551.6 EJP70161.1 - 0.18 12.4 0.3 0.7 10.5 0.0 2.1 2 0 0 2 2 2 0 MCM N-terminal domain TFIIA PF03153.13 EJP70161.1 - 0.27 11.2 8.7 0.36 10.8 8.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NmrA PF05368.13 EJP70163.1 - 3.3e-15 56.3 0.0 9.7e-15 54.7 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP70163.1 - 2.6e-07 30.7 0.1 6.7e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EJP70163.1 - 0.0075 15.7 0.1 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EJP70163.1 - 0.032 14.3 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Enterotoxin_a PF01375.17 EJP70164.1 - 1e-17 64.6 0.1 2.1e-16 60.3 0.1 2.1 1 1 0 1 1 1 1 Heat-labile enterotoxin alpha chain FAD_binding_7 PF03441.14 EJP70165.1 - 1.6e-75 253.0 0.1 2.2e-75 252.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EJP70165.1 - 4.8e-37 127.5 0.0 9e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase TPR_16 PF13432.6 EJP70166.1 - 0.00058 20.5 14.2 0.0012 19.4 0.9 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJP70166.1 - 0.00094 19.4 2.1 0.052 13.9 0.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP70166.1 - 0.0015 18.8 0.0 0.0047 17.1 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EJP70166.1 - 0.0042 17.1 0.5 0.12 12.5 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJP70166.1 - 0.0063 17.0 2.6 0.017 15.6 1.3 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EJP70166.1 - 0.091 12.7 2.1 0.19 11.6 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ETF_alpha PF00766.19 EJP70166.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain TPR_8 PF13181.6 EJP70166.1 - 0.19 12.0 0.9 2.1 8.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EJP70166.1 - 0.21 12.3 0.0 0.21 12.3 0.0 3.7 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EJP70166.1 - 0.29 12.0 10.6 0.34 11.8 0.1 4.1 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJP70166.1 - 0.38 11.5 5.1 12 6.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EJP70166.1 - 0.81 9.6 3.6 6.9 6.7 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 EJP70167.1 - 8.5e-17 61.6 1.1 8.5e-17 61.6 1.1 3.9 3 1 1 4 4 4 1 U3 snoRNA associated AIM3 PF17096.5 EJP70167.1 - 0.031 15.2 6.5 0.031 15.2 6.5 3.0 1 1 2 3 3 3 0 Altered inheritance of mitochondria protein 3 CDC45 PF02724.14 EJP70167.1 - 0.32 9.2 20.3 0.46 8.7 20.2 1.4 1 1 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EJP70167.1 - 3.6 7.3 24.9 2.3 7.9 8.1 2.3 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NADH-u_ox-rdase PF10785.9 EJP70168.1 - 0.03 15.0 0.0 0.054 14.2 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PH_10 PF15411.6 EJP70169.1 - 3.5e-28 98.3 0.2 5.7e-28 97.6 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EJP70169.1 - 6.8e-14 52.5 0.0 1.2e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EJP70169.1 - 4.4e-09 36.5 0.4 3.8e-08 33.4 0.4 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 EJP70169.1 - 0.00061 20.1 5.8 0.0011 19.3 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EJP70169.1 - 0.0049 16.8 5.5 0.0081 16.1 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EJP70169.1 - 0.0093 15.6 3.5 0.0093 15.6 3.5 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 EJP70169.1 - 0.019 15.3 2.8 0.042 14.1 2.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 EJP70169.1 - 0.026 14.8 4.5 0.045 14.1 4.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.6 EJP70169.1 - 0.032 14.1 5.1 0.06 13.2 5.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 EJP70169.1 - 0.13 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 PH domain zf-C3HC4 PF00097.25 EJP70169.1 - 0.17 11.8 5.8 0.3 11.0 5.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJP70169.1 - 0.17 11.7 4.7 0.35 10.7 4.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger DUF1147 PF06615.11 EJP70169.1 - 0.34 11.0 1.8 0.54 10.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) zf-C3H2C3 PF17122.5 EJP70169.1 - 1.2 9.2 5.3 2.7 8.1 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger PHD PF00628.29 EJP70169.1 - 3.7 7.5 4.6 7.1 6.6 4.6 1.5 1 0 0 1 1 1 0 PHD-finger Cpn60_TCP1 PF00118.24 EJP70170.1 - 1.2e-154 515.6 8.2 1.3e-154 515.4 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2204 PF09970.9 EJP70170.1 - 0.021 14.5 0.2 7.1 6.2 0.0 2.9 3 0 0 3 3 3 0 Nucleotidyl transferase of unknown function (DUF2204) PrpR_N PF06506.11 EJP70170.1 - 0.064 12.8 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Propionate catabolism activator HMG_box PF00505.19 EJP70171.1 - 0.00013 22.3 0.7 0.00032 21.0 0.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box CCDC106 PF15794.5 EJP70171.1 - 0.00036 20.3 2.2 0.00036 20.3 2.2 2.1 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 HMG_box_2 PF09011.10 EJP70171.1 - 0.0062 17.1 1.6 0.0062 17.1 1.6 1.9 2 0 0 2 2 2 1 HMG-box domain LCD1 PF09798.9 EJP70171.1 - 0.53 8.7 3.9 0.6 8.6 3.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein SlyX PF04102.12 EJP70171.1 - 0.78 10.4 7.1 3 8.5 0.2 3.2 2 1 1 3 3 3 0 SlyX DUF155 PF02582.14 EJP70172.1 - 5.3e-54 183.0 0.6 8.1e-54 182.4 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Sacchrp_dh_NADP PF03435.18 EJP70172.1 - 1.1e-16 61.2 0.1 3.4e-16 59.7 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EJP70172.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L37ae PF01780.19 EJP70173.1 - 5.4e-40 135.4 10.4 6.1e-40 135.2 10.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EJP70173.1 - 0.0045 17.1 1.1 0.0064 16.6 1.1 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EJP70173.1 - 0.011 15.6 4.7 0.02 14.9 4.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Sgf11 PF08209.11 EJP70173.1 - 0.049 13.2 1.1 0.24 11.0 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Elf1 PF05129.13 EJP70173.1 - 0.054 13.5 2.9 0.095 12.8 2.8 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 EJP70173.1 - 0.081 13.4 1.0 0.54 10.8 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.15 EJP70173.1 - 0.087 12.9 5.4 0.097 12.7 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 EJP70173.1 - 0.12 12.8 2.6 2 8.8 0.1 2.1 1 1 1 2 2 2 0 C1 domain zf-rbx1 PF12678.7 EJP70174.1 - 7e-09 35.8 18.0 4.2e-07 30.2 4.1 3.2 3 1 0 3 3 2 2 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EJP70174.1 - 2.4e-08 34.2 18.0 2.6e-07 30.9 0.4 3.7 3 1 0 3 3 3 1 Ring finger domain PHD PF00628.29 EJP70174.1 - 2.9e-08 33.5 7.2 2.9e-08 33.5 7.2 2.7 2 1 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EJP70174.1 - 6.2e-06 25.7 2.6 6.2e-06 25.7 2.6 2.3 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.6 EJP70174.1 - 2.1e-05 24.3 0.9 2.1e-05 24.3 0.9 2.9 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EJP70174.1 - 2.1e-05 24.3 1.2 2.1e-05 24.3 1.2 3.1 2 2 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EJP70174.1 - 0.00014 21.8 7.3 0.0074 16.3 0.2 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EJP70174.1 - 0.00034 20.5 0.6 0.00034 20.5 0.6 3.5 4 1 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EJP70174.1 - 0.00053 19.8 0.6 0.00053 19.8 0.6 3.8 3 1 2 5 5 4 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EJP70174.1 - 0.001 18.7 1.1 0.001 18.7 1.1 2.7 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EJP70174.1 - 0.0015 18.4 0.8 0.0015 18.4 0.8 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EJP70174.1 - 0.0036 17.1 0.6 3.8 7.4 0.4 2.6 2 0 0 2 2 2 2 Rad50 zinc hook motif Prok-RING_1 PF14446.6 EJP70174.1 - 0.011 15.6 2.5 0.011 15.6 2.5 2.8 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 zf-RING_6 PF14835.6 EJP70174.1 - 0.023 14.6 0.4 0.023 14.6 0.4 2.1 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-PHD-like PF15446.6 EJP70174.1 - 0.028 14.1 3.8 0.028 14.0 0.8 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.6 EJP70174.1 - 0.036 14.1 0.8 0.036 14.1 0.8 3.7 2 2 0 2 2 1 0 RING-type zinc-finger G10 PF01125.17 EJP70174.1 - 0.045 13.5 0.8 8.9 6.1 0.1 2.4 2 0 0 2 2 2 0 G10 protein zf-HC5HC2H PF13771.6 EJP70174.1 - 0.35 11.1 4.3 0.14 12.5 0.3 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING_4 PF14570.6 EJP70174.1 - 0.88 9.4 4.6 2 8.3 1.7 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_9 PF13901.6 EJP70174.1 - 0.98 9.4 9.5 7.1 6.6 0.3 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_3 PF13922.6 EJP70174.1 - 1.5 9.2 6.3 0.52 10.7 1.6 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx RINGv PF12906.7 EJP70174.1 - 5.5 7.2 10.5 0.54 10.4 3.0 2.7 2 0 0 2 2 2 0 RING-variant domain C1_2 PF03107.16 EJP70174.1 - 6.1 7.3 8.3 0.76 10.1 1.2 2.7 2 1 0 2 2 2 0 C1 domain zf-HC5HC2H_2 PF13832.6 EJP70174.1 - 8.4 6.6 8.4 1.3 9.3 2.8 2.4 1 1 1 2 2 2 0 PHD-zinc-finger like domain MRP-L46 PF11788.8 EJP70175.1 - 9.8e-24 84.4 0.0 1.5e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 VitD-bind_III PF09164.10 EJP70175.1 - 2.3 8.3 3.8 24 5.0 0.0 2.8 3 0 0 3 3 3 0 Vitamin D binding protein, domain III SMC_N PF02463.19 EJP70176.1 - 2.3e-62 210.3 15.1 4.6e-62 209.3 15.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EJP70176.1 - 2.1e-26 92.5 0.0 1.4e-25 89.8 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EJP70176.1 - 1.9e-20 74.3 0.6 1.9e-20 74.3 0.6 7.1 2 2 3 5 5 5 1 AAA domain AAA_15 PF13175.6 EJP70176.1 - 2.8e-19 70.1 39.2 5.5e-17 62.5 0.6 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EJP70176.1 - 1.9e-17 64.0 2.7 5.7e-09 36.2 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EJP70176.1 - 0.00054 20.1 0.0 0.0019 18.4 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EJP70176.1 - 0.0031 18.1 0.1 0.053 14.0 0.1 6.4 3 2 1 4 4 4 2 ABC transporter AAA_29 PF13555.6 EJP70176.1 - 0.0039 16.9 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 EJP70176.1 - 0.0067 15.8 8.9 0.0067 15.8 8.9 7.4 4 3 2 7 7 7 1 Growth-arrest specific micro-tubule binding PCI PF01399.27 EJP70176.1 - 0.041 14.4 1.1 0.54 10.8 0.6 3.1 2 1 1 3 3 3 0 PCI domain MFS_1 PF07690.16 EJP70177.1 - 4.3e-28 98.2 23.2 4.3e-28 98.2 23.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP70177.1 - 6.4e-09 35.2 2.9 1.6e-08 33.9 2.9 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter Folate_carrier PF01770.18 EJP70177.1 - 0.002 16.9 0.0 0.0048 15.7 0.0 1.6 1 0 0 1 1 1 1 Reduced folate carrier PQ-loop PF04193.14 EJP70178.1 - 1.3e-29 101.7 12.3 4.7e-15 55.1 0.1 2.7 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 EJP70178.1 - 0.01 15.8 0.5 4.5 7.4 0.1 3.1 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange GFO_IDH_MocA PF01408.22 EJP70179.1 - 1.1e-18 68.1 0.1 1.8e-18 67.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EJP70179.1 - 0.035 14.7 0.2 0.11 13.1 0.1 1.9 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CDC37_N PF03234.14 EJP70180.1 - 7.1e-46 156.3 0.4 7.1e-46 156.3 0.4 3.4 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EJP70180.1 - 5.7e-36 123.0 0.1 5.7e-36 123.0 0.1 2.4 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EJP70180.1 - 8.1e-33 112.5 10.7 3e-32 110.7 4.6 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain TPR_15 PF13429.6 EJP70180.1 - 0.0067 15.7 0.9 0.0067 15.7 0.9 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat LPD39 PF18858.1 EJP70180.1 - 0.038 14.1 7.4 9.4 6.3 0.1 4.3 4 0 0 4 4 4 0 Large polyvalent protein associated domain 39 MecA_N PF05223.11 EJP70180.1 - 0.069 13.4 0.5 0.3 11.4 0.5 2.1 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain ACC_epsilon PF13822.6 EJP70180.1 - 5.8 7.7 8.4 1.6 9.4 1.1 2.6 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit DUF3535 PF12054.8 EJP70181.1 - 5.1e-130 434.6 0.0 4.5e-129 431.5 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EJP70181.1 - 3.9e-67 226.5 0.0 1.1e-66 224.9 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP70181.1 - 2.2e-19 69.8 0.0 7.6e-19 68.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EJP70181.1 - 2.7e-17 61.4 3.1 0.0034 17.5 0.0 8.8 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 EJP70181.1 - 9.5e-10 38.7 3.0 0.00024 21.4 0.0 7.0 7 0 0 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EJP70181.1 - 1.6e-08 35.0 0.6 0.31 11.7 0.0 4.1 2 1 0 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EJP70181.1 - 0.00023 21.6 10.3 2 9.0 0.0 7.5 8 0 0 8 8 8 2 HEAT-like repeat UME PF08064.13 EJP70181.1 - 0.0079 16.1 3.0 12 5.9 0.0 5.1 5 2 2 7 7 7 1 UME (NUC010) domain CLASP_N PF12348.8 EJP70181.1 - 0.039 13.5 0.5 10 5.6 0.0 3.1 2 1 0 2 2 2 0 CLASP N terminal Adaptin_N PF01602.20 EJP70181.1 - 0.044 12.3 3.7 0.076 11.6 0.2 2.8 3 0 0 3 3 3 0 Adaptin N terminal region Thiamine_BP PF01910.17 EJP70183.1 - 3.3e-32 110.2 1.3 3.9e-32 110.0 1.3 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Polysacc_deac_1 PF01522.21 EJP70183.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF1682 PF07946.14 EJP70184.1 - 1.1e-110 369.9 0.9 1.3e-110 369.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) ThrE PF06738.12 EJP70185.1 - 3.1e-62 210.1 27.4 8.1e-62 208.7 3.6 2.4 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EJP70185.1 - 9.4e-11 42.0 14.2 9.4e-11 42.0 14.2 2.7 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF2651 PF10852.8 EJP70185.1 - 0.21 12.2 4.8 0.59 10.8 4.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) Haspin_kinase PF12330.8 EJP70188.1 - 2.4e-35 122.2 0.0 3.7e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain SET PF00856.28 EJP70188.1 - 5.7e-08 33.3 0.2 1.8e-07 31.7 0.0 1.9 2 1 0 2 2 2 1 SET domain Pex26 PF07163.12 EJP70189.1 - 0.00011 21.6 3.2 0.00011 21.6 3.2 2.0 1 1 1 2 2 2 1 Pex26 protein CDC45 PF02724.14 EJP70189.1 - 0.15 10.3 9.8 0.19 10.0 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 EJP70189.1 - 2.1 7.1 5.5 2.7 6.7 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5401 PF17380.2 EJP70189.1 - 9.6 4.1 22.9 14 3.6 22.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) PHF5 PF03660.14 EJP70190.1 - 8.5e-53 177.0 9.7 9.6e-53 176.8 9.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EJP70190.1 - 0.31 8.8 6.4 0.33 8.8 6.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EJP70190.1 - 2.4 8.3 15.7 5.7 7.0 2.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 EJP70191.1 - 8e-33 113.3 11.1 8e-33 113.3 11.1 2.5 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 EJP70191.1 - 0.0013 19.0 9.3 0.0013 19.0 9.3 3.4 2 1 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Abhydrolase_1 PF00561.20 EJP70192.1 - 4.4e-23 82.3 0.0 1.2e-22 80.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP70192.1 - 1.2e-17 65.3 2.2 1.4e-17 65.0 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP70192.1 - 5.9e-13 48.6 0.1 3.3e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EJP70192.1 - 0.18 11.9 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein PhoLip_ATPase_C PF16212.5 EJP70193.1 - 8.8e-84 281.2 18.7 8.8e-84 281.2 18.7 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EJP70193.1 - 1.6e-27 94.9 5.3 4.8e-27 93.5 5.3 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EJP70193.1 - 5.1e-12 45.7 0.0 4.4e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EJP70193.1 - 2.5e-11 44.3 3.1 3.5e-06 27.4 1.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EJP70193.1 - 2.1e-07 30.6 0.1 5.3e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EJP70193.1 - 0.0021 17.8 0.5 0.0097 15.7 0.4 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Mt_ATP-synt_B PF05405.14 EJP70193.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ecl1 PF12855.7 EJP70194.1 - 1.1e-28 101.6 24.8 1.1e-28 101.6 24.8 2.1 1 1 1 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 EJP70194.1 - 0.0049 16.9 1.3 0.0091 16.1 1.3 1.4 1 0 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 EJP70194.1 - 0.032 13.7 5.4 0.076 12.5 5.4 1.5 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 EJP70194.1 - 2.4 8.4 6.4 21 5.3 6.4 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) PHC2_SAM_assoc PF16616.5 EJP70195.1 - 0.68 10.8 9.7 11 6.9 4.1 2.2 1 1 1 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 SYF2 PF08231.12 EJP70197.1 - 2.5e-55 187.2 15.2 2.5e-55 187.2 15.2 1.8 2 0 0 2 2 2 1 SYF2 splicing factor Epimerase PF01370.21 EJP70198.1 - 3.2e-07 30.1 0.0 5.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP70198.1 - 7.8e-07 29.2 0.0 1.1e-05 25.4 0.0 2.6 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EJP70198.1 - 4.6e-05 22.6 0.0 0.00019 20.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EJP70198.1 - 0.0082 15.3 0.7 0.042 13.0 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EJP70198.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EJP70198.1 - 0.035 13.2 0.0 0.12 11.5 0.0 1.9 3 0 0 3 3 3 0 RmlD substrate binding domain YEATS PF03366.16 EJP70199.1 - 4.3e-29 100.3 0.2 6.9e-29 99.7 0.2 1.3 1 0 0 1 1 1 1 YEATS family Amidase PF01425.21 EJP70200.1 - 3.1e-100 336.3 0.0 5.5e-100 335.4 0.0 1.4 1 1 0 1 1 1 1 Amidase Nucleoside_tran PF01733.18 EJP70201.1 - 7.9e-43 147.0 0.1 2e-42 145.7 0.0 1.6 1 1 1 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 EJP70201.1 - 9.5e-05 21.5 33.5 0.025 13.5 3.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1345 PF07077.11 EJP70201.1 - 0.019 14.7 7.8 0.065 12.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) Ins_P5_2-kin PF06090.12 EJP70202.1 - 2.3e-34 119.3 0.0 1.6e-33 116.5 0.0 2.0 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Tmemb_cc2 PF10267.9 EJP70203.1 - 0.13 11.4 3.0 0.17 11.0 3.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein HET PF06985.11 EJP70204.1 - 6.7e-22 78.4 4.0 8e-22 78.2 0.1 2.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) His_biosynth PF00977.21 EJP70205.1 - 2.8e-36 125.1 0.0 3.4e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 EJP70205.1 - 0.029 13.7 0.1 0.63 9.3 0.1 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase Ribul_P_3_epim PF00834.19 EJP70205.1 - 0.057 12.8 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family PH PF00169.29 EJP70206.1 - 3.5e-09 37.1 0.0 1.2e-08 35.4 0.0 1.9 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 EJP70206.1 - 2.2e-08 34.6 0.2 8.3e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Cell division protein anillin PH_11 PF15413.6 EJP70206.1 - 0.018 15.4 0.0 0.06 13.8 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain DUF1899 PF08953.11 EJP70207.1 - 2.8e-35 120.0 0.0 5.9e-35 119.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EJP70207.1 - 8.2e-20 70.4 0.2 1.6e-19 69.5 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EJP70207.1 - 1.4e-15 57.4 2.8 0.00068 20.4 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP70207.1 - 4.7e-08 33.2 0.0 0.00058 20.1 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP70207.1 - 0.00041 19.1 0.1 0.57 8.8 0.0 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 SlyX PF04102.12 EJP70207.1 - 1.1 9.9 7.7 0.46 11.1 4.5 1.9 2 0 0 2 2 2 0 SlyX CorA PF01544.18 EJP70208.1 - 1.6e-10 40.8 0.6 1.6e-10 40.8 0.6 2.3 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein Cwf_Cwc_15 PF04889.12 EJP70208.1 - 0.00018 21.3 8.8 0.00037 20.3 8.8 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FixP_N PF14715.6 EJP70208.1 - 0.035 13.8 0.2 0.035 13.8 0.2 2.7 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Ni_hydr_CYTB PF01292.20 EJP70208.1 - 1.1 8.8 7.8 2.5 7.6 7.8 1.6 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2614 PF11023.8 EJP70208.1 - 3.1 7.9 6.5 0.7 10.0 0.9 2.3 2 1 0 2 2 2 0 Zinc-ribbon containing domain STE PF02200.16 EJP70209.1 - 4.4e-56 188.0 0.2 8.1e-56 187.2 0.2 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EJP70209.1 - 1.1e-10 41.3 13.8 2.7e-06 27.5 0.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP70209.1 - 2.8e-09 37.0 3.1 2.8e-09 37.0 3.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP70209.1 - 3.2e-07 30.6 11.9 0.0005 20.7 0.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EJP70209.1 - 6.9e-05 22.7 0.5 6.9e-05 22.7 0.5 3.4 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP70209.1 - 0.018 15.3 3.6 0.1 12.9 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 EJP70209.1 - 0.055 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon zf_UBZ PF18439.1 EJP70209.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EJP70209.1 - 0.12 12.7 3.4 0.21 11.9 3.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF4602 PF15375.6 EJP70210.1 - 3.7e-08 33.8 14.2 4.3e-08 33.6 2.8 3.1 3 1 0 3 3 3 2 Domain of unknown function (DUF4602) Lin-8 PF03353.15 EJP70210.1 - 0.099 12.2 5.0 0.14 11.7 5.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 EJP70210.1 - 0.34 10.3 23.0 0.55 9.6 23.0 1.4 1 1 0 1 1 1 0 SDA1 STG PF15809.5 EJP70210.1 - 1.1 9.3 4.8 4.4 7.3 0.5 2.2 1 1 1 2 2 2 0 Simian taste bud-specific gene product family BCNT PF07572.12 EJP70211.1 - 1.9e-22 79.1 0.8 4e-22 78.1 0.8 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development SPT6_acidic PF14632.6 EJP70211.1 - 0.021 15.4 12.7 0.044 14.4 11.7 2.1 1 1 0 1 1 1 0 Acidic N-terminal SPT6 WD40 PF00400.32 EJP70212.1 - 2.3e-09 37.7 14.4 0.0027 18.5 0.4 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Cwf_Cwc_15 PF04889.12 EJP70212.1 - 4.7 6.9 12.2 0.053 13.2 1.9 2.5 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein SNF2_N PF00176.23 EJP70213.1 - 1.2e-73 247.9 0.3 1.2e-73 247.9 0.3 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP70213.1 - 1e-21 77.3 0.4 5.1e-18 65.4 0.0 3.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Bromodomain PF00439.25 EJP70213.1 - 2.6e-19 69.1 0.3 6.3e-19 67.8 0.3 1.7 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 EJP70213.1 - 7e-17 61.5 12.1 7e-17 61.5 12.1 5.1 5 0 0 5 5 5 1 HSA SnAC PF14619.6 EJP70213.1 - 8.7e-15 55.1 0.5 8.7e-15 55.1 0.5 4.3 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 EJP70213.1 - 5.7e-11 42.0 5.9 5.7e-11 42.0 5.9 2.3 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 EJP70213.1 - 4.6e-10 39.8 0.0 4.6e-10 39.8 0.0 4.2 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit RBR PF17208.3 EJP70213.1 - 0.0028 18.3 9.2 0.0028 18.3 9.2 2.5 1 1 1 2 2 2 1 RNA binding Region Abhydrolase_6 PF12697.7 EJP70214.1 - 0.0041 17.8 3.5 0.036 14.6 3.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EJP70214.1 - 0.0081 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EJP70214.1 - 0.025 14.3 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 EJP70214.1 - 0.061 12.6 0.4 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EJP70214.1 - 0.062 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PTPLA PF04387.14 EJP70215.1 - 1.3e-51 174.7 15.2 1.3e-51 174.7 15.2 1.9 2 1 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Peptidase_M1 PF01433.20 EJP70216.1 - 2.3e-74 249.6 2.5 3.6e-74 249.0 2.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EJP70216.1 - 2.4e-56 191.6 0.2 1.3e-54 185.9 0.0 2.5 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EJP70216.1 - 2.4e-42 145.2 0.5 4.1e-42 144.5 0.1 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain LBP_BPI_CETP PF01273.25 EJP70216.1 - 0.04 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain DIOX_N PF14226.6 EJP70217.1 - 7.6e-21 75.1 0.0 3.9e-20 72.8 0.0 2.0 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EJP70217.1 - 6.2e-19 68.4 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.14 EJP70218.1 - 2.1e-27 96.7 0.0 4.3e-27 95.6 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 EJP70218.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase DnaJ PF00226.31 EJP70219.1 - 2.7e-15 56.2 0.2 2.7e-15 56.2 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain BAF1_ABF1 PF04684.13 EJP70219.1 - 0.19 10.7 14.4 0.25 10.4 14.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF5401 PF17380.2 EJP70219.1 - 0.39 8.7 30.1 0.56 8.2 30.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Dynamin_N PF00350.23 EJP70219.1 - 0.7 9.9 4.4 26 4.8 5.1 2.7 2 1 0 2 2 2 0 Dynamin family Presenilin PF01080.17 EJP70219.1 - 3.1 6.5 13.6 3.6 6.2 13.6 1.1 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 EJP70219.1 - 4.6 6.3 25.7 7.8 5.5 25.7 1.4 1 0 0 1 1 1 0 SprA-related family V_ATPase_I PF01496.19 EJP70219.1 - 6.2 4.6 10.3 6.9 4.4 10.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.9 EJP70219.1 - 7.9 5.8 26.2 3.8 6.9 0.2 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 CRT10 PF08728.10 EJP70219.1 - 8.7 4.4 6.7 11 4.0 6.7 1.1 1 0 0 1 1 1 0 CRT10 Amidohydro_1 PF01979.20 EJP70220.1 - 1.5e-53 182.3 0.1 1.8e-53 182.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EJP70220.1 - 2.8e-11 43.6 0.7 1.2e-07 31.6 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family DUF2235 PF09994.9 EJP70221.1 - 3e-67 227.0 0.0 7.9e-66 222.3 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BppU_IgG PF18667.1 EJP70221.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain zf-C2H2 PF00096.26 EJP70222.1 - 0.029 14.8 0.1 0.029 14.8 0.1 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP70222.1 - 0.059 14.2 1.4 0.082 13.8 0.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger GCV_T PF01571.21 EJP70223.1 - 4.2e-08 32.9 0.0 0.00036 20.0 0.0 2.3 1 1 1 2 2 2 2 Aminomethyltransferase folate-binding domain TFIIE-A_C PF11521.8 EJP70224.1 - 0.015 15.6 3.4 0.015 15.6 3.4 3.4 2 1 1 3 3 3 0 C-terminal general transcription factor TFIIE alpha BUD22 PF09073.10 EJP70224.1 - 0.11 11.8 16.0 0.14 11.5 16.0 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EJP70224.1 - 0.71 8.1 16.3 0.68 8.1 15.4 1.3 1 1 0 1 1 1 0 CDC45-like protein DUF4724 PF15852.5 EJP70224.1 - 1.3 9.5 5.9 14 6.2 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) DEAD PF00270.29 EJP70225.1 - 2.3e-40 138.2 0.0 5.5e-40 137.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP70225.1 - 1.2e-30 106.2 0.0 2.3e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP70225.1 - 3.7e-05 23.8 0.0 8.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EJP70225.1 - 0.0064 15.2 0.0 0.0096 14.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 EJP70225.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 EJP70225.1 - 0.14 12.4 0.1 1.5 9.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 EJP70226.1 - 6.2e-62 209.4 0.0 7.4e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70226.1 - 2.2e-33 115.6 0.0 3.1e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP70226.1 - 6.1e-06 25.8 0.0 9.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EJP70226.1 - 0.00052 18.9 0.0 0.00073 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase TruD PF01142.18 EJP70227.1 - 2.4e-55 188.1 0.0 1.1e-53 182.6 0.0 2.4 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) MarR_2 PF12802.7 EJP70227.1 - 0.017 15.0 0.0 0.79 9.7 0.0 3.0 3 0 0 3 3 3 0 MarR family Rotamase_3 PF13616.6 EJP70228.1 - 5.9e-16 59.1 1.1 1.1e-15 58.1 0.1 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.21 EJP70228.1 - 1.5e-13 51.5 0.0 1.5e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EJP70228.1 - 0.0013 19.5 0.2 0.0015 19.4 0.2 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Ribosomal_L7Ae PF01248.26 EJP70229.1 - 2.5e-28 97.7 1.0 3.1e-28 97.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S8 PF00410.19 EJP70230.1 - 8.4e-22 77.5 0.1 1.3e-21 76.9 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Fungal_trans_2 PF11951.8 EJP70232.1 - 2e-08 33.5 0.9 2e-08 33.5 0.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain SPX PF03105.19 EJP70232.1 - 0.13 12.2 9.1 0.2 11.6 9.1 1.3 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EJP70232.1 - 0.16 10.8 7.9 0.18 10.6 7.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Fungal_trans PF04082.18 EJP70233.1 - 3.4e-14 52.5 0.0 5.1e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PsbT PF01405.17 EJP70233.1 - 0.059 13.2 0.5 0.13 12.1 0.5 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre T protein ABC2_membrane PF01061.24 EJP70234.1 - 3.2e-82 275.0 40.6 3.6e-45 154.0 10.3 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EJP70234.1 - 6.5e-40 136.8 0.0 9.1e-19 68.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EJP70234.1 - 8.4e-25 86.5 0.4 2.1e-23 82.0 0.0 2.8 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 EJP70234.1 - 2.4e-07 30.2 30.2 4.1e-05 22.9 11.1 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 EJP70234.1 - 3.2e-07 30.9 0.3 0.00081 19.8 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EJP70234.1 - 3.1e-06 26.9 0.0 0.00085 18.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EJP70234.1 - 2.8e-05 24.1 0.1 0.00064 19.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 EJP70234.1 - 3.7e-05 24.2 0.0 8.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_29 PF13555.6 EJP70234.1 - 5.7e-05 22.8 0.1 0.0085 15.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EJP70234.1 - 0.00079 19.7 0.0 0.89 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EJP70234.1 - 0.0011 19.2 0.0 0.47 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EJP70234.1 - 0.0047 16.5 1.2 0.61 9.7 0.5 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EJP70234.1 - 0.0065 16.7 1.0 0.77 10.0 0.6 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EJP70234.1 - 0.01 15.7 0.5 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EJP70234.1 - 0.014 15.9 0.0 3.6 8.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 EJP70234.1 - 0.015 15.0 0.5 2 8.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EJP70234.1 - 0.018 14.8 0.0 0.97 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DnaB_C PF03796.15 EJP70234.1 - 0.025 13.9 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA PF00004.29 EJP70234.1 - 0.049 14.0 0.0 8.7 6.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EJP70234.1 - 0.15 12.6 0.1 0.3 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EJP70234.1 - 0.18 11.1 0.0 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 EJP70234.1 - 0.19 11.5 0.4 4.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.19 EJP70234.1 - 0.19 11.1 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EJP70234.1 - 0.22 11.6 0.2 17 5.5 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase CAP59_mtransfer PF11735.8 EJP70235.1 - 3.6e-59 200.4 0.0 4.8e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_transf_90 PF05686.12 EJP70236.1 - 2.3e-11 43.2 9.8 1.3e-08 34.2 5.3 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 Paf1 PF03985.13 EJP70237.1 - 1.4e-104 350.5 5.7 1.5e-104 350.3 5.7 1.0 1 0 0 1 1 1 1 Paf1 Rer1 PF03248.13 EJP70238.1 - 4.1e-79 264.2 8.8 4.8e-79 264.0 8.8 1.0 1 0 0 1 1 1 1 Rer1 family DUF4131 PF13567.6 EJP70238.1 - 0.069 12.8 2.2 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Na_Pi_cotrans PF02690.15 EJP70238.1 - 0.72 10.0 5.0 0.68 10.0 0.4 2.0 2 0 0 2 2 2 0 Na+/Pi-cotransporter Ank_2 PF12796.7 EJP70239.1 - 2e-11 44.3 0.1 7e-08 33.0 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP70239.1 - 2.8e-09 37.3 0.4 0.28 11.8 0.0 5.3 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EJP70239.1 - 1e-07 32.1 1.5 0.0039 17.6 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 EJP70239.1 - 1.2e-06 28.3 2.1 0.004 17.5 0.0 4.8 5 1 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EJP70239.1 - 7.7e-06 26.1 0.1 0.0015 18.8 0.0 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) ECH_1 PF00378.20 EJP70240.1 - 4.2e-78 262.1 0.1 4.8e-78 261.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJP70240.1 - 1.6e-35 123.2 0.3 1.5e-34 120.0 0.3 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4522 PF15022.6 EJP70240.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) SH3_1 PF00018.28 EJP70241.1 - 1.1e-05 24.9 0.0 3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP70241.1 - 0.00039 20.2 0.3 0.00039 20.2 0.3 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EJP70241.1 - 0.077 12.7 1.2 0.19 11.4 0.1 2.2 2 0 0 2 2 2 0 Variant SH3 domain PALP PF00291.25 EJP70242.1 - 2.6e-67 227.3 0.5 3.4e-67 226.9 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L19 PF01245.20 EJP70244.1 - 1.4e-11 44.3 0.0 2.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 CH PF00307.31 EJP70245.1 - 1.3e-46 157.3 0.3 1.9e-22 79.5 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EJP70245.1 - 1.7e-23 82.5 0.1 6.2e-23 80.7 0.1 2.1 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EJP70245.1 - 6.2e-12 45.2 1.4 1.4e-06 28.1 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_8 PF13833.6 EJP70245.1 - 0.0002 21.2 0.2 0.55 10.1 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair CH_2 PF06294.11 EJP70245.1 - 0.00037 20.5 0.0 0.019 15.0 0.0 3.3 3 0 0 3 3 3 1 CH-like domain in sperm protein EF-hand_6 PF13405.6 EJP70245.1 - 0.00044 20.0 0.4 0.0045 16.8 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EJP70245.1 - 0.0013 19.2 1.2 0.0064 16.9 1.2 2.3 1 0 0 1 1 1 1 EF-hand domain pair YjcZ PF13990.6 EJP70245.1 - 0.026 13.9 0.7 1.8 7.8 0.0 2.4 1 1 1 2 2 2 0 YjcZ-like protein Spectrin PF00435.21 EJP70245.1 - 0.045 14.2 4.1 6 7.4 1.1 2.8 2 0 0 2 2 2 0 Spectrin repeat EF-hand_1 PF00036.32 EJP70245.1 - 0.054 13.1 0.4 0.76 9.5 0.0 2.7 2 0 0 2 2 2 0 EF hand Fib_alpha PF08702.10 EJP70245.1 - 0.11 12.7 0.6 2.9 8.0 0.1 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4508 PF14969.6 EJP70245.1 - 0.26 11.6 3.6 3.3 8.0 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) EHN PF06441.12 EJP70246.1 - 8.2e-36 122.7 0.2 3e-35 120.9 0.0 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus MID_pPIWI_RE PF18157.1 EJP70246.1 - 0.16 12.3 0.1 0.88 9.9 0.0 2.0 2 0 0 2 2 2 0 MID domain of pPIWI_RE FAD-oxidase_C PF02913.19 EJP70247.1 - 9.6e-61 205.6 0.0 1.3e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EJP70247.1 - 1.3e-36 125.4 0.4 2.6e-36 124.4 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 EJP70248.1 - 2.7e-05 24.2 11.9 4.8e-05 23.4 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP70248.1 - 0.0018 17.2 0.1 0.0027 16.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Prenyltransf PF01255.19 EJP70250.1 - 3.5e-05 23.5 0.0 0.00015 21.4 0.0 1.8 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase TetR_C_7 PF14246.6 EJP70250.1 - 0.1 12.7 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Proteasome PF00227.26 EJP70251.1 - 1e-55 188.2 0.3 1.5e-55 187.7 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJP70251.1 - 1.1e-11 44.2 0.4 3.6e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ERCC3_RAD25_C PF16203.5 EJP70252.1 - 1.5e-120 401.0 0.2 2.4e-120 400.3 0.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EJP70252.1 - 7e-34 116.7 0.0 5.1e-33 113.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP70252.1 - 9.2e-15 55.1 0.0 1.8e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EJP70252.1 - 1.2e-11 44.9 0.0 2.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EJP70252.1 - 2.1e-07 30.0 0.0 2.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rep_fac_C PF08542.11 EJP70252.1 - 0.16 12.4 0.0 0.59 10.6 0.0 1.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain TrkH PF02386.16 EJP70253.1 - 6.5e-135 450.4 1.8 6.5e-135 450.4 1.8 1.6 2 0 0 2 2 2 1 Cation transport protein NPDC1 PF06809.11 EJP70253.1 - 0.01 14.9 0.3 0.018 14.1 0.3 1.3 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) VPS9 PF02204.18 EJP70254.1 - 4.3e-25 87.9 0.0 8.4e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EJP70254.1 - 0.066 13.5 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) AMP-binding PF00501.28 EJP70255.1 - 1.4e-71 241.3 0.0 1.7e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP70255.1 - 4e-19 69.4 0.1 1.1e-18 67.9 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ICL PF00463.21 EJP70256.1 - 1.1e-296 984.5 0.8 1.2e-296 984.3 0.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EJP70256.1 - 2.3e-11 43.6 0.2 5.5e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.18 EJP70258.1 - 2.6e-188 627.0 0.0 3.1e-188 626.8 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EJP70258.1 - 7.2e-16 57.6 0.2 1.2e-15 56.9 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Yippee-Mis18 PF03226.14 EJP70259.1 - 1.9e-19 69.8 0.0 2.9e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C3HC PF07967.13 EJP70259.1 - 0.056 13.5 0.1 8.8 6.4 0.2 2.2 2 0 0 2 2 2 0 C3HC zinc finger-like Rsm1 PF08600.10 EJP70259.1 - 0.083 13.1 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Rsm1-like RIG-I_C-RD PF11648.8 EJP70259.1 - 0.16 12.2 1.0 0.41 10.9 0.1 1.9 2 0 0 2 2 2 0 C-terminal domain of RIG-I DUF678 PF05077.12 EJP70259.1 - 0.71 10.0 3.8 2.7 8.2 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF678) Ank_2 PF12796.7 EJP70260.1 - 1.1e-62 208.6 0.9 1.2e-15 57.8 0.0 4.3 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 EJP70260.1 - 2.9e-39 131.8 4.4 1.4e-05 25.3 0.1 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EJP70260.1 - 1.5e-38 130.7 0.3 3.3e-09 37.1 0.0 6.2 3 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP70260.1 - 2.1e-38 125.9 1.0 8.9e-05 22.6 0.0 7.9 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EJP70260.1 - 9.8e-34 115.0 3.2 7.7e-07 29.3 0.1 6.9 2 1 5 7 7 7 6 Ankyrin repeats (many copies) F-box-like PF12937.7 EJP70260.1 - 0.0031 17.4 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJP70260.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain Peptidase_M20 PF01546.28 EJP70263.1 - 1.1e-32 113.4 0.1 1.5e-32 113.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJP70263.1 - 5.3e-11 42.4 0.0 9.8e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MatE PF01554.18 EJP70264.1 - 0.0001 22.0 26.0 0.0031 17.2 7.2 3.9 3 1 1 4 4 4 2 MatE DWNN PF08783.11 EJP70265.1 - 2.9e-30 104.4 0.4 6e-30 103.3 0.1 1.7 2 0 0 2 2 1 1 DWNN domain zf-CCHC_2 PF13696.6 EJP70265.1 - 1.8e-08 34.1 6.8 1.8e-08 34.1 6.8 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EJP70265.1 - 0.00059 19.8 1.9 0.0011 18.9 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 EJP70265.1 - 0.00067 19.4 9.4 0.00067 19.4 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EJP70265.1 - 0.0019 18.0 5.5 0.0041 16.9 5.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 EJP70265.1 - 0.0067 16.7 7.0 0.0067 16.7 7.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-CCHC_3 PF13917.6 EJP70265.1 - 0.045 13.7 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-RING_6 PF14835.6 EJP70265.1 - 0.099 12.5 2.7 0.2 11.5 2.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 EJP70265.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-C3HC4 PF00097.25 EJP70265.1 - 0.22 11.4 8.9 0.47 10.4 8.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP70265.1 - 0.41 10.6 12.9 0.065 13.2 7.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EJP70265.1 - 0.73 10.0 8.0 2.1 8.6 8.0 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FYVE_2 PF02318.16 EJP70265.1 - 1.1 9.4 4.5 0.73 10.1 2.3 1.8 2 0 0 2 2 1 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 EJP70265.1 - 2.8 7.9 10.8 0.26 11.2 5.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ArsA_ATPase PF02374.15 EJP70266.1 - 1.4e-108 362.7 0.0 1.7e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 EJP70266.1 - 1.5e-12 47.7 0.0 2.5e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EJP70266.1 - 1.5e-12 47.8 0.0 4.7e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EJP70266.1 - 6.9e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EJP70266.1 - 3.1e-05 23.6 0.2 0.00021 20.8 0.0 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EJP70266.1 - 0.00012 21.6 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 EJP70266.1 - 0.00015 21.5 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EJP70266.1 - 0.05 13.2 0.2 0.084 12.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EJP70266.1 - 0.057 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 EJP70266.1 - 0.071 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EJP70266.1 - 0.074 13.6 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Transthyretin PF00576.21 EJP70268.1 - 2.1e-35 121.8 0.0 2.4e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 EJP70268.1 - 0.0008 19.6 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain FAST_2 PF08368.12 EJP70268.1 - 0.049 14.4 0.0 0.081 13.7 0.0 1.3 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 DUF4597 PF15366.6 EJP70269.1 - 0.033 13.9 1.5 0.08 12.7 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) APH PF01636.23 EJP70270.1 - 3.2e-09 37.1 0.2 6.8e-09 36.0 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP70270.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase CDC50 PF03381.15 EJP70271.1 - 3e-100 335.3 0.1 3.7e-100 335.0 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.11 EJP70272.1 - 6e-55 185.6 0.2 6e-55 185.6 0.2 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EJP70272.1 - 1.8e-52 177.4 0.6 7.3e-52 175.4 0.6 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EJP70272.1 - 6.6e-26 91.3 0.0 1.2e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EJP70272.1 - 2.5e-15 56.7 1.4 6.8e-15 55.2 0.2 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 EJP70272.1 - 0.18 12.0 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Arm-DNA-bind_4 PF14657.6 EJP70272.1 - 5.5 6.8 7.1 2.9 7.7 1.6 2.8 2 0 0 2 2 2 0 Arm DNA-binding domain CMD PF02627.20 EJP70273.1 - 1.1e-07 31.8 0.2 6.5e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family MMTV_SAg PF01054.17 EJP70274.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Gcn1_N PF12074.8 EJP70274.1 - 0.065 12.5 0.5 1.6 8.0 0.3 2.0 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal CYYR1 PF10873.8 EJP70274.1 - 0.086 13.3 0.9 0.16 12.4 0.9 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF327 PF03885.13 EJP70274.1 - 0.14 12.1 0.2 0.22 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF327) COPIIcoated_ERV PF07970.12 EJP70275.1 - 1.7e-85 286.3 0.0 4.8e-85 284.9 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EJP70275.1 - 2e-30 105.0 0.0 4.2e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.12 EJP70276.1 - 2.9e-10 40.5 6.3 0.0054 17.4 0.1 3.8 4 0 0 4 4 4 3 Sel1 repeat Proteasome PF00227.26 EJP70277.1 - 8.6e-48 162.4 0.1 1.1e-47 162.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EJP70277.1 - 1.8e-10 40.0 0.2 1.8e-10 40.0 0.2 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Herpes_gE PF02480.16 EJP70279.1 - 0.018 13.8 0.1 0.023 13.4 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1180 PF06679.12 EJP70279.1 - 0.43 11.0 6.2 0.45 10.9 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) CAP59_mtransfer PF11735.8 EJP70280.1 - 6.2e-71 238.9 0.0 7.8e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ANAPC4_WD40 PF12894.7 EJP70281.1 - 0.00045 20.5 0.0 0.0027 18.0 0.0 2.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain NUP214 PF16755.5 EJP70281.1 - 0.0022 17.3 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Nucleoporin_FG PF13634.6 EJP70281.1 - 0.013 16.3 9.6 0.013 16.3 9.6 8.5 4 1 2 7 7 7 0 Nucleoporin FG repeat region WD40 PF00400.32 EJP70281.1 - 0.75 10.8 3.4 0.39 11.7 0.2 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat RNA_pol_A_bac PF01000.26 EJP70282.1 - 2.2e-25 89.2 0.0 4.3e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EJP70282.1 - 5.2e-20 70.6 0.0 7.2e-20 70.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.21 EJP70283.1 - 1.2e-60 204.9 0.0 2.4e-60 203.9 0.0 1.3 1 1 0 1 1 1 1 ThiF family E2_bind PF08825.10 EJP70283.1 - 4.5e-29 100.4 0.1 7.7e-29 99.7 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 EJP70283.1 - 0.00047 20.7 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 EJP70283.1 - 0.23 11.5 0.5 1.6 8.8 0.0 2.2 2 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 EJP70283.1 - 0.28 11.1 0.7 12 5.7 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Telomere_reg-2 PF10193.9 EJP70284.1 - 9.3e-38 129.0 0.0 3.5e-37 127.2 0.0 2.1 1 0 0 1 1 1 1 Telomere length regulation protein SYCE1 PF15233.6 EJP70284.1 - 0.0092 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 AlaE PF06610.13 EJP70284.1 - 0.11 12.5 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 L-alanine exporter Pkinase PF00069.25 EJP70285.1 - 3.3e-56 190.6 0.0 4.6e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70285.1 - 1.6e-40 139.1 0.0 2.3e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJP70285.1 - 0.0019 17.2 0.1 0.13 11.2 0.0 2.3 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EJP70285.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJP70285.1 - 0.032 14.2 0.0 0.17 11.8 0.0 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP70285.1 - 0.075 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EJP70285.1 - 0.08 11.7 0.1 0.24 10.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 EJP70285.1 - 0.17 11.5 0.0 1.9 8.1 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HrpB7 PF09486.10 EJP70286.1 - 0.17 12.3 9.4 0.3 11.5 9.4 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4746 PF15928.5 EJP70286.1 - 0.56 9.6 6.0 0.81 9.1 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 EJP70286.1 - 8.7 5.2 11.7 13 4.6 11.7 1.2 1 0 0 1 1 1 0 Paf1 APH PF01636.23 EJP70287.1 - 1.7e-44 152.5 0.0 6e-44 150.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EJP70287.1 - 7.3e-07 28.8 0.0 1.9e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EJP70287.1 - 4.7e-06 26.3 0.0 7.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EJP70287.1 - 0.0013 18.1 0.0 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EJP70287.1 - 0.0095 15.6 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Fructosamin_kin PF03881.14 EJP70287.1 - 0.012 14.9 0.0 0.15 11.2 0.0 2.1 1 1 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.25 EJP70287.1 - 0.016 14.5 0.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 EJP70287.1 - 0.055 12.3 0.0 0.12 11.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) CBFB_NFYA PF02045.15 EJP70288.1 - 1.1e-27 96.4 6.1 2.5e-27 95.2 6.1 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 EJP70288.1 - 0.026 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein Metallophos PF00149.28 EJP70291.1 - 7.8e-08 33.1 0.0 1.6e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJP70291.1 - 4.7e-05 23.7 0.0 0.00034 20.8 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1996 PF09362.10 EJP70292.1 - 9.5e-67 225.4 0.5 1.1e-66 225.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Mu-like_gpT PF10124.9 EJP70292.1 - 0.054 12.8 0.3 0.29 10.4 0.1 1.9 2 0 0 2 2 2 0 Mu-like prophage major head subunit gpT Laminin_I PF06008.14 EJP70293.1 - 6.2 6.4 6.1 7.1 6.2 0.4 2.1 1 1 0 2 2 2 0 Laminin Domain I PMM PF03332.13 EJP70294.1 - 9.4e-104 346.0 0.0 1.1e-103 345.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EJP70294.1 - 0.01 15.6 0.0 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP70294.1 - 0.15 12.4 0.0 6 7.2 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase WW PF00397.26 EJP70295.1 - 9e-12 44.9 0.2 2.5e-11 43.5 0.2 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 EJP70295.1 - 3.7e-05 22.9 0.2 0.00033 19.8 0.2 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase MutS_V PF00488.21 EJP70296.1 - 8.5e-71 237.9 0.2 1.5e-70 237.0 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EJP70296.1 - 2.6e-35 122.4 1.6 2.6e-35 122.4 1.6 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EJP70296.1 - 3.3e-29 101.4 0.0 7e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EJP70296.1 - 9.8e-10 38.8 0.0 2.7e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EJP70296.1 - 0.00079 19.7 0.0 0.0037 17.6 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV DUF4911 PF16256.5 EJP70296.1 - 0.0071 16.3 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) AAA_27 PF13514.6 EJP70296.1 - 0.062 12.9 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Prenyltrans PF00432.21 EJP70298.1 - 1.3e-60 200.7 2.4 6.4e-13 48.2 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EJP70298.1 - 1.8e-06 27.3 0.0 0.053 12.6 0.0 3.8 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EJP70298.1 - 4.4e-06 26.0 0.0 0.00069 18.8 0.0 2.9 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain Pkinase PF00069.25 EJP70299.1 - 3.5e-13 49.5 0.0 5.8e-12 45.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70299.1 - 4.8e-12 45.7 0.0 6.1e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RhoGAP PF00620.27 EJP70300.1 - 1.2e-28 99.9 0.0 1.9e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.12 EJP70301.1 - 7e-58 195.1 0.1 8.2e-58 194.8 0.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 EJP70302.1 - 1e-78 264.6 0.0 1.3e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EJP70302.1 - 0.00065 20.1 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EJP70302.1 - 0.017 15.1 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EJP70302.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EJP70302.1 - 0.15 11.8 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 EJP70303.1 - 4.1e-104 346.6 0.0 6.9e-104 345.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJP70303.1 - 9.3e-31 106.3 0.7 1.6e-30 105.6 0.7 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EJP70303.1 - 4.5e-21 75.1 1.4 9.9e-21 74.0 1.4 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EJP70303.1 - 1.9e-19 70.1 1.3 1.9e-19 70.1 1.3 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EJP70303.1 - 4.6e-08 32.7 0.1 9.4e-06 25.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EJP70303.1 - 7.6e-06 26.0 0.1 5.2e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EJP70303.1 - 0.0068 16.2 0.1 0.024 14.5 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 EJP70303.1 - 0.0092 16.6 0.4 0.0092 16.6 0.4 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 EJP70303.1 - 0.017 15.0 0.0 0.057 13.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJP70303.1 - 0.13 11.9 0.0 0.67 9.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 EJP70304.1 - 2.3e-56 189.9 0.0 5.1e-43 146.7 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EJP70304.1 - 5.7e-28 97.1 0.1 1.5e-27 95.8 0.1 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EJP70304.1 - 1.1e-13 50.8 0.1 1.2e-08 34.6 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EJP70304.1 - 2.7e-10 40.9 5.9 4.1e-05 24.0 0.2 4.3 2 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EJP70304.1 - 9.6e-09 35.6 0.0 0.00027 21.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EJP70304.1 - 8.4e-07 28.7 0.0 2.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EJP70304.1 - 9.3e-07 29.2 2.3 0.0066 16.7 0.1 3.8 3 2 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EJP70304.1 - 1.6e-06 28.7 0.4 0.0031 18.1 0.3 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EJP70304.1 - 6.4e-06 26.2 0.3 0.014 15.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 EJP70304.1 - 1.4e-05 25.1 1.0 0.0049 16.8 0.0 3.3 3 1 0 3 3 3 1 NACHT domain TsaE PF02367.17 EJP70304.1 - 1.5e-05 25.0 0.2 0.018 15.0 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EJP70304.1 - 1.8e-05 24.9 0.0 0.25 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EJP70304.1 - 1.9e-05 24.5 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EJP70304.1 - 3.3e-05 23.3 0.0 0.039 13.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EJP70304.1 - 0.00012 22.1 0.0 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EJP70304.1 - 0.00054 20.0 0.2 0.02 14.8 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EJP70304.1 - 0.0019 17.6 0.2 0.93 8.8 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EJP70304.1 - 0.002 17.4 0.1 0.56 9.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 EJP70304.1 - 0.0023 18.3 0.1 4.7 7.6 0.0 3.0 3 0 0 3 3 2 0 RNA helicase PEX-2N PF09263.10 EJP70304.1 - 0.0025 18.1 0.4 0.69 10.3 0.1 2.9 2 1 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal Sigma54_activat PF00158.26 EJP70304.1 - 0.003 17.3 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 EJP70304.1 - 0.004 17.4 0.1 1.2 9.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EJP70304.1 - 0.0042 16.8 0.1 3 7.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 EJP70304.1 - 0.01 16.3 0.1 2.9 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 EJP70304.1 - 0.01 16.0 0.3 1.3 9.1 0.2 2.6 2 0 0 2 2 2 0 Shikimate kinase ABC_tran PF00005.27 EJP70304.1 - 0.013 16.0 0.1 3.5 8.1 0.0 3.1 3 0 0 3 3 2 0 ABC transporter APS_kinase PF01583.20 EJP70304.1 - 0.018 14.9 0.5 0.059 13.3 0.1 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 EJP70304.1 - 0.021 14.4 3.7 9 5.8 0.2 3.7 2 2 1 4 4 4 0 AAA domain ATPase PF06745.13 EJP70304.1 - 0.021 14.2 0.0 3 7.1 0.0 2.4 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 EJP70304.1 - 0.025 14.7 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 EJP70304.1 - 0.028 14.6 0.0 9.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family NB-ARC PF00931.22 EJP70304.1 - 0.036 13.3 1.3 14 4.8 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain Viral_helicase1 PF01443.18 EJP70304.1 - 0.042 13.6 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 EJP70304.1 - 0.042 13.3 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 EJP70304.1 - 0.046 13.0 0.0 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 EJP70304.1 - 0.054 12.7 0.1 0.57 9.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EJP70304.1 - 0.056 13.2 0.2 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EJP70304.1 - 0.084 12.8 0.1 0.82 9.6 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_3 PF07726.11 EJP70304.1 - 0.097 12.5 0.0 8.7 6.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EJP70304.1 - 0.15 11.0 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EJP70304.1 - 0.48 10.0 2.2 3.1 7.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Inositol_P PF00459.25 EJP70305.1 - 6.9e-40 137.3 0.1 4e-39 134.8 0.1 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family SNF2_N PF00176.23 EJP70306.1 - 1e-53 182.3 0.0 1.6e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EJP70306.1 - 1.3e-26 92.2 5.0 9e-17 60.7 0.8 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EJP70306.1 - 5.8e-19 68.5 0.0 1.4e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 EJP70306.1 - 2.5e-17 63.1 0.4 1.1e-16 61.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 EJP70306.1 - 8.9e-09 34.9 0.1 3.8e-08 32.8 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EJP70306.1 - 0.00013 22.0 0.0 0.00064 19.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 EJP70306.1 - 0.00021 21.6 2.1 0.00021 21.6 2.1 4.6 3 1 1 4 4 4 1 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 EJP70306.1 - 0.013 16.1 1.1 0.013 16.1 1.1 2.7 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 AAA_22 PF13401.6 EJP70306.1 - 0.094 13.0 0.0 0.33 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJP70307.1 - 3.6e-32 111.8 0.0 1.4e-15 58.0 0.0 2.8 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 EJP70307.1 - 4.2e-12 45.7 4.4 4.2e-12 45.7 4.4 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 EJP70307.1 - 4.9e-11 42.5 1.0 0.00027 20.4 0.1 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP70307.1 - 3.7e-09 36.8 10.5 0.22 11.3 1.8 4.6 3 2 2 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EJP70307.1 - 1.1e-05 25.4 0.1 0.16 11.7 0.0 3.4 3 1 1 4 4 4 2 AAA ATPase domain Fer4 PF00037.27 EJP70307.1 - 1.1e-05 25.0 2.7 1.1e-05 25.0 2.7 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_16 PF13191.6 EJP70307.1 - 1.1e-05 25.8 0.0 0.03 14.7 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EJP70307.1 - 1.8e-05 25.0 0.0 0.0033 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EJP70307.1 - 3.2e-05 24.4 0.1 0.043 14.2 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Fer4_10 PF13237.6 EJP70307.1 - 9.7e-05 22.4 8.5 0.0051 16.9 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Rad17 PF03215.15 EJP70307.1 - 0.00014 21.8 0.0 0.013 15.4 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_23 PF13476.6 EJP70307.1 - 0.00021 21.9 0.0 0.049 14.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EJP70307.1 - 0.00027 20.9 0.0 0.65 9.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 EJP70307.1 - 0.00033 20.5 0.1 0.097 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 EJP70307.1 - 0.00048 20.2 10.1 0.00097 19.2 10.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.6 EJP70307.1 - 0.00061 20.3 0.1 1.6 9.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EJP70307.1 - 0.0009 19.6 0.0 0.39 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 EJP70307.1 - 0.0013 18.4 0.1 1.7 8.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EJP70307.1 - 0.0025 17.7 1.3 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 EJP70307.1 - 0.0035 17.1 0.6 3.2 7.4 0.0 2.9 3 0 0 3 3 3 1 Thymidylate kinase Fer4_6 PF12837.7 EJP70307.1 - 0.0035 17.3 1.7 0.0035 17.3 1.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 EJP70307.1 - 0.0038 17.4 0.1 0.53 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EJP70307.1 - 0.0044 16.7 2.7 0.13 11.8 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_7 PF12838.7 EJP70307.1 - 0.0049 17.4 6.5 0.012 16.1 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain NB-ARC PF00931.22 EJP70307.1 - 0.0073 15.5 0.0 0.6 9.3 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain TsaE PF02367.17 EJP70307.1 - 0.0084 16.1 0.1 0.077 13.0 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 EJP70307.1 - 0.0094 14.6 2.2 0.012 14.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 EJP70307.1 - 0.018 14.5 0.2 0.37 10.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EJP70307.1 - 0.021 14.8 0.5 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EJP70307.1 - 0.027 14.7 0.6 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EJP70307.1 - 0.037 13.7 0.1 4 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 EJP70307.1 - 0.041 14.0 10.2 0.092 12.9 10.2 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EJP70307.1 - 0.099 13.6 0.2 0.099 13.6 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain VirE PF05272.11 EJP70307.1 - 0.12 12.1 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E PduV-EutP PF10662.9 EJP70307.1 - 0.13 12.0 3.9 0.72 9.6 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EJP70307.1 - 0.21 11.6 1.1 35 4.4 0.0 3.2 3 1 0 3 3 2 0 AAA domain MukB PF04310.12 EJP70307.1 - 0.24 11.1 0.5 25 4.6 0.0 2.6 3 0 0 3 3 2 0 MukB N-terminal MMR_HSR1 PF01926.23 EJP70307.1 - 0.41 10.7 1.5 31 4.7 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EJP70307.1 - 0.43 10.5 2.2 6.5 6.6 0.1 2.5 2 0 0 2 2 2 0 NTPase Fer4_2 PF12797.7 EJP70307.1 - 1.2 9.4 10.2 0.33 11.1 1.0 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.19 EJP70308.1 - 1.3e-42 143.7 14.1 4.9e-12 45.8 0.2 5.7 5 0 0 5 5 5 5 FF domain WW PF00397.26 EJP70308.1 - 5.3e-17 61.6 18.2 7e-09 35.6 4.5 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EJP70308.1 - 0.0053 17.4 9.8 16 6.3 0.0 4.7 2 1 2 4 4 4 2 p190-A and -B Rho GAPs FF domain Lipin_mid PF16876.5 EJP70308.1 - 0.12 12.6 0.9 4 7.6 0.1 2.7 1 1 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Glyco_hyd_101C PF17451.2 EJP70308.1 - 1.5 9.1 7.1 16 5.8 1.6 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 EJP70309.1 - 3.3e-107 358.6 0.0 5.9e-107 357.7 0.0 1.4 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 SLD3 PF08639.10 EJP70310.1 - 1.9e-157 525.3 7.6 1.9e-157 525.3 7.6 2.5 3 0 0 3 3 3 1 DNA replication regulator SLD3 Dicty_REP PF05086.12 EJP70310.1 - 0.056 11.4 0.1 0.089 10.8 0.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Homeodomain PF00046.29 EJP70311.1 - 4.4e-15 55.3 3.1 9.2e-15 54.2 3.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EJP70311.1 - 0.0047 16.8 1.2 0.011 15.6 1.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Podoplanin PF05808.11 EJP70311.1 - 1.2 9.2 3.8 7.7 6.6 0.1 3.1 3 1 1 4 4 4 0 Podoplanin HET PF06985.11 EJP70312.1 - 1.5e-27 96.7 0.0 4.3e-27 95.2 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 EJP70312.1 - 0.094 12.8 0.3 0.31 11.2 0.3 2.0 1 0 0 1 1 1 0 WW domain AAA_12 PF13087.6 EJP70313.1 - 1.1e-18 67.6 0.0 3.5e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EJP70313.1 - 1.4e-16 61.1 0.0 3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP70313.1 - 1.1e-05 25.2 0.0 0.21 11.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EJP70313.1 - 0.0001 22.7 0.0 0.00056 20.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJP70313.1 - 0.012 16.0 0.4 0.098 13.0 0.3 2.7 2 1 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.9 EJP70313.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 EJP70313.1 - 0.029 13.6 0.1 0.054 12.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EJP70313.1 - 0.035 13.9 0.0 1.2 8.8 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EJP70313.1 - 0.12 12.3 1.9 14 5.6 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 EJP70313.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PBP PF01161.20 EJP70314.1 - 9.1e-15 55.1 0.0 1e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FAD_binding_4 PF01565.23 EJP70315.1 - 1.3e-17 63.9 2.0 2.6e-17 62.9 2.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EJP70315.1 - 0.0024 17.9 0.0 0.0079 16.3 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like EXS PF03124.14 EJP70316.1 - 7.8e-115 383.7 7.6 8.9e-115 383.5 7.6 1.0 1 0 0 1 1 1 1 EXS family NUDIX PF00293.28 EJP70318.1 - 5.6e-08 32.9 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Ctr PF04145.15 EJP70319.1 - 1.1e-31 110.5 3.0 1.8e-31 109.8 3.0 1.3 1 1 0 1 1 1 1 Ctr copper transporter family 3-HAO PF06052.12 EJP70320.1 - 8.2e-62 207.3 0.0 9.2e-62 207.1 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EJP70320.1 - 4e-06 26.4 0.0 5.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 EJP70320.1 - 0.00033 20.9 0.1 0.00044 20.5 0.1 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_1 PF00190.22 EJP70320.1 - 0.00055 19.6 0.1 0.00074 19.2 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EJP70320.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_4 PF08007.12 EJP70320.1 - 0.035 13.6 0.0 0.069 12.6 0.0 1.4 1 1 0 1 1 1 0 Cupin superfamily protein FAA_hydrolase PF01557.18 EJP70321.1 - 1.3e-51 175.4 0.0 1.6e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cullin PF00888.22 EJP70322.1 - 2.6e-192 640.8 3.0 3.1e-192 640.5 3.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EJP70322.1 - 1.9e-25 88.7 0.1 6.9e-25 86.9 0.1 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain LSM PF01423.22 EJP70323.1 - 1.1e-16 60.2 0.0 1.4e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EJP70323.1 - 0.00045 20.3 0.0 0.00064 19.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 EJP70323.1 - 3.7 6.3 3.9 4.6 5.9 3.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MTS PF05175.14 EJP70324.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Peptidase_S9 PF00326.21 EJP70326.1 - 3.9e-20 72.2 0.3 6.7e-20 71.5 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EJP70326.1 - 5.5e-05 22.8 0.1 0.0001 21.9 0.1 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 EJP70326.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EJP70326.1 - 0.0083 16.8 0.2 0.02 15.5 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJP70326.1 - 0.011 15.0 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PD40 PF07676.12 EJP70326.1 - 0.022 14.7 0.7 0.53 10.3 0.1 3.0 2 1 1 3 3 3 0 WD40-like Beta Propeller Repeat DRMBL PF07522.14 EJP70328.1 - 2.2e-34 117.9 0.0 4.1e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EJP70328.1 - 6.7e-07 29.0 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LSM PF01423.22 EJP70329.1 - 6e-18 64.3 0.4 8.2e-18 63.9 0.4 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EJP70329.1 - 0.0044 16.6 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Hfq protein DUF2469 PF10611.9 EJP70329.1 - 0.08 13.5 0.0 0.098 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) Rax2 PF12768.7 EJP70330.1 - 9.4e-68 227.9 0.0 7.3e-67 225.0 0.0 2.5 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Kelch_6 PF13964.6 EJP70330.1 - 0.0024 18.1 0.3 0.31 11.4 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 EJP70330.1 - 0.011 15.3 3.1 0.31 10.7 0.1 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 EJP70330.1 - 4 7.8 6.9 1.6 9.1 0.3 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain SNase PF00565.17 EJP70331.1 - 1.8e-24 86.2 0.0 2.7e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue P34-Arc PF04045.14 EJP70332.1 - 6.6e-101 337.0 0.4 7.9e-101 336.8 0.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Protamine_3 PF08188.11 EJP70332.1 - 0.12 12.6 1.2 0.22 11.7 1.2 1.4 1 0 0 1 1 1 0 Spermatozal protamine family WD40 PF00400.32 EJP70333.1 - 1e-49 165.4 34.0 8.6e-06 26.4 0.5 11.8 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 EJP70333.1 - 6.5e-19 68.2 0.1 1.5e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EJP70333.1 - 1.7e-17 63.5 3.3 0.013 15.8 0.0 8.5 4 2 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EJP70333.1 - 2.2e-05 24.0 0.0 2.2 7.6 0.0 3.6 3 0 0 3 3 3 3 WD40-like domain eIF2A PF08662.11 EJP70333.1 - 0.00016 21.6 0.1 0.26 11.1 0.0 4.6 4 2 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EJP70333.1 - 0.00055 19.0 1.7 1 8.2 0.0 4.4 4 2 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EJP70333.1 - 0.00067 18.4 6.9 0.27 9.9 0.0 5.6 5 2 0 6 6 6 1 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 EJP70333.1 - 0.0032 16.8 0.0 1.6 7.9 0.0 3.1 3 0 0 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus NINJA_B PF16136.5 EJP70333.1 - 0.054 13.9 0.7 0.13 12.6 0.7 1.6 1 0 0 1 1 1 0 Putative nuclear localisation signal Frtz PF11768.8 EJP70333.1 - 0.057 11.7 0.1 0.65 8.3 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 EJP70333.1 - 0.16 11.6 0.2 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EJP70333.1 - 0.18 10.5 4.5 23 3.6 0.0 4.6 4 1 0 5 5 5 0 Nup133 N terminal like zf-C2H2 PF00096.26 EJP70334.1 - 6.3e-10 39.0 11.6 2.4e-05 24.5 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJP70334.1 - 4.7e-09 36.3 13.7 4e-05 23.8 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJP70334.1 - 9.7e-07 29.1 10.6 0.0014 19.3 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EJP70334.1 - 6.2e-06 26.4 1.3 1.9e-05 24.9 1.3 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EJP70334.1 - 6.8e-05 22.8 8.5 0.00013 21.9 2.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP70334.1 - 0.00066 19.9 4.2 0.0008 19.6 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EJP70334.1 - 0.048 14.0 2.1 0.061 13.7 1.3 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 EJP70334.1 - 0.48 10.4 4.4 13 5.8 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EJP70334.1 - 0.51 10.1 9.8 2.2 8.1 0.5 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type SF3b1 PF08920.10 EJP70336.1 - 3e-20 72.9 3.4 1e-19 71.2 3.4 1.9 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EJP70336.1 - 9.1e-13 48.4 7.3 0.1 13.0 0.1 7.8 4 3 2 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 EJP70336.1 - 2e-12 47.3 1.5 0.016 15.7 0.0 7.6 7 1 1 8 8 7 2 HEAT-like repeat HEAT PF02985.22 EJP70336.1 - 3.2e-10 39.4 8.2 0.74 10.2 0.0 9.1 9 0 0 9 9 9 4 HEAT repeat Cnd1 PF12717.7 EJP70336.1 - 6.9e-08 32.7 0.3 1.6 8.8 0.0 6.2 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EJP70336.1 - 2e-05 23.4 0.7 0.0088 14.6 0.1 3.5 2 2 2 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EJP70336.1 - 3.7e-05 24.2 0.2 1.8 9.2 0.0 5.6 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 EJP70336.1 - 6.2e-05 22.7 0.5 0.9 9.2 0.0 4.6 3 1 1 5 5 5 2 NUC173 domain DUF3385 PF11865.8 EJP70336.1 - 7.9e-05 22.6 1.0 0.02 14.8 0.0 4.9 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) UNC45-central PF11701.8 EJP70336.1 - 0.0022 18.0 0.0 0.0075 16.2 0.0 1.9 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central DRIM PF07539.12 EJP70336.1 - 0.0066 14.8 0.3 2.5 6.3 0.1 3.9 2 1 2 4 4 4 2 Down-regulated in metastasis CLASP_N PF12348.8 EJP70336.1 - 0.011 15.3 0.1 1.8 8.1 0.0 3.8 5 0 0 5 5 5 0 CLASP N terminal MMS19_C PF12460.8 EJP70336.1 - 0.12 11.4 0.0 11 5.0 0.0 3.5 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal OGG_N PF07934.12 EJP70337.1 - 5.5e-22 78.1 0.0 1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EJP70337.1 - 4.7e-17 62.4 0.0 8.2e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EJP70337.1 - 7.4e-05 22.4 0.0 0.00018 21.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.22 EJP70338.1 - 3.3e-29 100.5 0.1 1.4e-12 47.2 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S13_N PF08069.12 EJP70339.1 - 4.6e-30 103.4 0.1 7.9e-30 102.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EJP70339.1 - 3.6e-15 55.9 0.1 5.5e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EJP70339.1 - 0.018 14.9 0.1 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.13 EJP70340.1 - 2.2e-14 52.9 0.0 3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.11 EJP70341.1 - 9.4e-24 83.6 0.0 2.2e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Macoilin PF09726.9 EJP70342.1 - 4.9 5.6 5.9 5.7 5.4 5.9 1.1 1 0 0 1 1 1 0 Macoilin family Na_Ca_ex PF01699.24 EJP70343.1 - 4.5e-50 169.5 38.9 1.5e-27 96.4 17.5 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MARVEL PF01284.23 EJP70343.1 - 2.8 8.0 27.7 0.42 10.6 0.1 4.7 2 2 2 4 4 4 0 Membrane-associating domain Cnd2 PF05786.14 EJP70344.1 - 1.7e-302 1005.9 4.8 2.1e-302 1005.5 4.8 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EJP70344.1 - 0.028 14.6 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal HMG_box PF00505.19 EJP70345.1 - 6.2e-15 55.4 0.8 6.2e-15 55.4 0.8 2.6 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EJP70345.1 - 6e-12 46.0 1.0 6e-12 46.0 1.0 2.1 2 0 0 2 2 2 1 HMG-box domain SAM_1 PF00536.30 EJP70345.1 - 1.2e-10 41.7 0.0 2.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EJP70345.1 - 9.3e-09 35.3 0.3 2.1e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) 4HB_MCP_1 PF12729.7 EJP70345.1 - 1.1 8.8 4.1 1.7 8.2 4.1 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction adh_short_C2 PF13561.6 EJP70346.1 - 9e-55 185.8 3.0 1e-54 185.6 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP70346.1 - 2.9e-43 147.6 0.6 3.6e-43 147.3 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP70346.1 - 5.4e-10 39.5 1.0 6.8e-10 39.1 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJP70346.1 - 0.0011 18.5 0.1 0.012 15.1 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJP70346.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DLH PF01738.18 EJP70347.1 - 0.0006 19.4 0.1 0.0078 15.8 0.1 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EJP70347.1 - 0.00076 19.1 0.5 0.0012 18.5 0.5 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EJP70347.1 - 0.0022 17.3 0.1 0.0045 16.3 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 EJP70347.1 - 0.027 13.2 0.1 0.066 11.9 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 EJP70347.1 - 0.041 13.8 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 EJP70347.1 - 0.13 10.8 0.2 0.19 10.2 0.2 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF3425 PF11905.8 EJP70348.1 - 1.7e-16 60.3 1.8 1.7e-16 60.3 1.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Dscam_C PF12355.8 EJP70348.1 - 0.009 17.0 0.9 0.023 15.6 0.9 1.7 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal HAMP PF00672.25 EJP70349.1 - 1.8e-39 133.9 14.5 2.1e-08 34.4 0.1 7.2 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 EJP70349.1 - 5.4e-31 107.4 0.8 2.1e-30 105.5 0.2 2.3 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EJP70349.1 - 7.6e-27 93.7 0.3 8.9e-26 90.3 0.2 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EJP70349.1 - 1.7e-16 60.0 0.6 1.7e-16 60.0 0.6 3.7 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain Fib_alpha PF08702.10 EJP70349.1 - 0.0052 17.0 27.6 0.52 10.5 0.9 6.2 6 0 0 6 6 6 2 Fibrinogen alpha/beta chain family DUF4279 PF14106.6 EJP70349.1 - 0.0085 16.3 0.0 66 3.8 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4279) DUF948 PF06103.11 EJP70349.1 - 0.014 15.6 40.7 2 8.8 3.1 9.1 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF948) GLE1 PF07817.13 EJP70349.1 - 0.036 13.3 2.9 7.6 5.7 0.1 3.8 3 1 1 4 4 4 0 GLE1-like protein GatB_Yqey PF02637.18 EJP70349.1 - 0.079 12.8 4.1 0.19 11.6 0.1 3.5 4 0 0 4 4 4 0 GatB domain GhoS PF11080.8 EJP70349.1 - 0.097 12.7 5.1 0.47 10.5 0.1 3.3 3 0 0 3 3 3 0 Endoribonuclease GhoS PMC2NT PF08066.12 EJP70349.1 - 0.13 13.0 4.1 3.4 8.4 1.6 4.4 3 1 1 4 4 4 0 PMC2NT (NUC016) domain BORCS6 PF10157.9 EJP70349.1 - 0.95 9.7 8.6 7.2 6.8 0.1 4.8 3 2 2 5 5 5 0 BLOC-1-related complex sub-unit 6 DUF883 PF05957.13 EJP70349.1 - 1.4 9.6 15.3 3.5 8.3 0.2 5.7 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF4795 PF16043.5 EJP70349.1 - 3 7.4 22.2 0.97 9.0 4.2 5.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4795) SNARE_assoc PF09335.11 EJP70350.1 - 3.4e-13 50.1 8.0 3.4e-13 50.1 8.0 2.1 3 0 0 3 3 3 1 SNARE associated Golgi protein Rhomboid PF01694.22 EJP70350.1 - 0.19 11.7 11.1 0.044 13.8 6.0 2.1 2 0 0 2 2 2 0 Rhomboid family Preseq_ALAS PF09029.10 EJP70351.1 - 4.2 7.9 5.8 47 4.5 0.0 3.0 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence Abhydrolase_1 PF00561.20 EJP70352.1 - 4.4e-13 49.5 0.0 7.8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP70352.1 - 4.9e-09 35.8 0.0 8.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP70352.1 - 0.00034 21.3 0.4 0.004 17.8 0.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EJP70352.1 - 0.0019 17.7 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EJP70352.1 - 0.005 16.5 0.1 0.046 13.3 0.1 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.12 EJP70352.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Med10 PF09748.9 EJP70353.1 - 1.7e-51 173.2 0.1 2.1e-51 173.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 EJP70353.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) TALPID3 PF15324.6 EJP70353.1 - 7.5 4.1 9.4 12 3.4 9.4 1.3 1 0 0 1 1 1 0 Hedgehog signalling target TPR_1 PF00515.28 EJP70354.1 - 2.5e-35 118.9 10.8 3.1e-06 26.8 0.2 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EJP70354.1 - 1.6e-34 115.2 10.8 7.7e-05 22.5 0.0 8.6 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 EJP70354.1 - 2.7e-29 100.6 10.9 4.2e-09 36.0 0.1 7.1 5 2 2 7 7 7 4 TPR repeat DnaJ PF00226.31 EJP70354.1 - 1.3e-27 95.7 4.4 1.9e-27 95.1 2.9 2.2 2 0 0 2 2 1 1 DnaJ domain TPR_19 PF14559.6 EJP70354.1 - 3.6e-23 81.8 9.3 8e-06 26.3 0.0 6.0 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 EJP70354.1 - 3.9e-20 72.2 8.3 2.4e-07 31.3 0.9 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EJP70354.1 - 1.4e-19 68.6 3.5 0.012 15.7 0.6 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EJP70354.1 - 1.3e-17 63.0 11.0 0.002 18.8 0.0 8.2 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EJP70354.1 - 1.3e-14 54.2 8.4 0.0002 21.6 0.1 6.1 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EJP70354.1 - 2.2e-13 49.6 8.8 0.011 16.1 0.1 6.0 7 0 0 7 7 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EJP70354.1 - 4.5e-12 46.0 1.4 0.00023 21.3 0.0 3.9 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EJP70354.1 - 4.1e-11 42.9 4.7 0.0002 21.4 0.2 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EJP70354.1 - 9.4e-09 35.4 9.1 1 10.1 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 EJP70354.1 - 7.8e-08 31.9 4.0 0.018 14.3 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJP70354.1 - 7.5e-07 28.8 1.8 7 6.9 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF627 PF04781.12 EJP70354.1 - 0.011 15.8 0.9 5.3 7.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF627) ChAPs PF09295.10 EJP70354.1 - 0.036 13.1 0.1 3.6 6.5 0.0 2.6 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 EJP70354.1 - 0.045 14.1 3.1 3.3 8.1 0.0 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat RRM_3 PF08777.11 EJP70354.1 - 0.046 13.8 0.5 0.96 9.5 0.0 2.5 2 1 0 2 2 2 0 RNA binding motif SRP_TPR_like PF17004.5 EJP70354.1 - 0.048 13.7 1.9 0.74 9.9 0.3 2.9 2 1 0 3 3 2 0 Putative TPR-like repeat Coatomer_E PF04733.14 EJP70354.1 - 0.053 12.9 0.4 18 4.6 0.0 3.2 2 1 2 4 4 4 0 Coatomer epsilon subunit TPR_10 PF13374.6 EJP70354.1 - 0.1 12.5 7.9 9.1 6.3 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat OST_P2 PF18235.1 EJP70354.1 - 0.11 12.5 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Oligosaccharyltransferase Peripheral 2 domain SHNi-TPR PF10516.9 EJP70354.1 - 0.23 11.0 2.7 4.8 6.7 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.18 EJP70354.1 - 2.6 8.2 8.7 4.6 7.4 0.1 3.8 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain EF-hand_6 PF13405.6 EJP70355.1 - 3.6e-12 45.2 0.0 5.2e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EJP70355.1 - 1.2e-10 40.1 1.0 0.00016 21.0 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EJP70355.1 - 9.7e-09 35.6 0.4 2.4e-08 34.3 0.4 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EJP70355.1 - 9e-08 31.9 0.2 0.0071 16.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EJP70355.1 - 4.5e-07 29.1 2.6 0.0024 17.3 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EJP70355.1 - 0.18 12.2 0.0 30 5.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Afi1 PF07792.12 EJP70356.1 - 1.9e-47 161.0 1.4 1.9e-47 161.0 1.4 1.7 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 EJP70356.1 - 7.8e-36 122.5 0.0 1.5e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EJP70356.1 - 3.4e-08 32.6 0.0 0.0094 14.7 0.0 3.8 3 1 1 4 4 4 2 Transport protein Avl9 DUF1168 PF06658.12 EJP70356.1 - 0.00087 19.1 6.7 0.002 18.0 6.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Nop53 PF07767.11 EJP70356.1 - 0.0055 16.2 3.2 0.0098 15.3 3.2 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF2347 PF09804.9 EJP70356.1 - 0.18 11.3 0.0 0.93 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DNA_pol_phi PF04931.13 EJP70356.1 - 2.2 6.3 9.9 3.5 5.6 9.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 EJP70356.1 - 3.4 7.6 9.5 5.9 6.8 9.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFAP1 PF06991.11 EJP70356.1 - 5.3 6.8 13.9 0.98 9.2 9.7 1.8 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing NOA36 PF06524.12 EJP70356.1 - 5.4 6.3 17.0 9.2 5.5 17.0 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EJP70356.1 - 7.6 6.5 8.8 18 5.3 8.8 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 EJP70356.1 - 7.9 4.9 8.3 13 4.2 8.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Esterase PF00756.20 EJP70357.1 - 2.5e-42 145.2 0.0 3e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EJP70357.1 - 0.001 18.4 0.0 0.0054 16.0 0.1 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP70357.1 - 0.032 14.8 1.4 0.056 14.0 1.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EJP70357.1 - 0.041 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 EJP70357.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) RNA_pol_Rpb6 PF01192.22 EJP70359.1 - 4.5e-16 58.5 0.1 9e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 MFS_1 PF07690.16 EJP70359.1 - 2.4e-14 53.1 27.2 3.6e-14 52.5 27.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 EJP70360.1 - 3.6e-29 99.6 56.0 0.00013 22.2 2.2 10.4 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP70360.1 - 1.2e-19 69.3 63.9 0.002 18.8 2.3 10.8 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EJP70360.1 - 5.3e-15 55.1 52.6 0.00025 21.3 0.2 10.7 11 0 0 11 11 11 5 Zinc-finger double domain FOXP-CC PF16159.5 EJP70360.1 - 1.6e-09 38.2 37.2 0.011 16.4 1.7 7.4 6 1 1 7 7 7 4 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 EJP70360.1 - 5.3e-06 26.6 16.1 0.0084 16.4 2.9 4.6 2 1 2 4 4 4 3 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 EJP70360.1 - 1.4e-05 25.8 20.3 0.0017 19.0 0.4 4.7 1 1 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats Ogr_Delta PF04606.12 EJP70360.1 - 0.0064 16.4 2.4 1.7 8.7 0.3 3.1 2 0 0 2 2 2 2 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 EJP70360.1 - 0.0091 15.7 0.0 0.0091 15.7 0.0 5.3 6 0 0 6 6 5 1 zinc-finger C2H2-type zinc_ribbon_10 PF10058.9 EJP70360.1 - 0.014 15.2 0.5 3.6 7.4 0.0 3.6 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-H2C2_5 PF13909.6 EJP70360.1 - 0.021 14.5 1.2 0.021 14.5 1.2 8.7 11 1 0 11 11 10 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EJP70360.1 - 0.34 11.0 0.0 0.34 11.0 0.0 6.8 9 0 0 9 9 9 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP70360.1 - 0.62 10.4 29.3 1.7 9.0 0.0 8.3 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 EJP70360.1 - 0.76 9.5 20.2 0.11 12.1 0.3 5.3 5 1 2 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 EJP70360.1 - 0.79 10.1 42.9 0.078 13.3 4.6 6.9 4 2 4 8 8 7 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EJP70360.1 - 1 9.9 0.0 1 9.9 0.0 6.4 7 0 0 7 7 6 0 Zinc-finger of C2H2 type zinc_ribbon_5 PF13719.6 EJP70360.1 - 2.2 8.1 10.9 4.3 7.2 0.2 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 EJP70360.1 - 7.6 6.5 8.3 4 7.4 0.1 4.2 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) Zip PF02535.22 EJP70361.1 - 4.1e-31 108.4 8.6 3.9e-21 75.6 3.8 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter MFS_1 PF07690.16 EJP70361.1 - 0.0028 16.7 18.2 0.011 14.7 10.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TPR_12 PF13424.6 EJP70361.1 - 0.0095 16.2 1.2 0.015 15.5 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3984 PF13136.6 EJP70362.1 - 6.9e-55 186.8 30.9 1.1e-53 182.8 30.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) CENP-B_dimeris PF09026.10 EJP70362.1 - 5.6 7.4 11.5 0.69 10.3 5.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain IKI3 PF04762.12 EJP70363.1 - 2.5e-292 972.3 0.0 3.2e-292 972.0 0.0 1.1 1 0 0 1 1 1 1 IKI3 family SGTA_dimer PF16546.5 EJP70363.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Homodimerisation domain of SGTA AIP3 PF03915.13 EJP70364.1 - 1.2e-150 502.2 6.2 1.2e-150 502.2 6.2 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 DUF1664 PF07889.12 EJP70364.1 - 0.00035 20.6 5.9 0.11 12.6 0.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) Wtap PF17098.5 EJP70364.1 - 0.0059 16.6 2.1 0.013 15.5 0.0 2.6 3 0 0 3 3 3 1 WTAP/Mum2p family Lectin_N PF03954.14 EJP70364.1 - 0.011 15.5 4.8 0.016 14.9 0.2 3.2 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain T7SS_ESX_EspC PF10824.8 EJP70364.1 - 0.041 14.4 3.5 1.3 9.5 0.8 3.7 2 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm EMP24_GP25L PF01105.24 EJP70364.1 - 0.22 11.4 1.8 0.59 10.0 0.0 2.6 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD Syntaxin_2 PF14523.6 EJP70364.1 - 0.23 11.9 9.6 30 5.1 0.1 4.6 5 0 0 5 5 5 0 Syntaxin-like protein NPV_P10 PF05531.12 EJP70364.1 - 0.35 11.3 8.8 0.58 10.7 0.2 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EJP70364.1 - 0.49 10.6 8.9 3.7 7.7 0.5 3.9 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family CHDCT2 PF08074.11 EJP70364.1 - 9 6.4 8.8 5.4 7.2 0.0 3.8 3 1 1 4 4 4 0 CHDCT2 (NUC038) domain Peptidase_C12 PF01088.21 EJP70365.1 - 2.8e-51 174.3 0.0 3.1e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Sugar_tr PF00083.24 EJP70366.1 - 3.9e-106 355.6 15.2 4.7e-106 355.4 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP70366.1 - 1.5e-23 83.3 35.5 1.5e-23 83.3 35.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 EJP70366.1 - 0.083 11.6 4.0 0.17 10.6 0.2 2.3 2 0 0 2 2 2 0 LacY proton/sugar symporter DUF3188 PF11384.8 EJP70366.1 - 3.4 7.4 8.4 0.31 10.8 2.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) MFS_1 PF07690.16 EJP70367.1 - 3.1e-39 134.9 41.4 3.1e-39 134.9 41.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EJP70368.1 - 2.9e-66 224.1 0.0 3.6e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4653 PF15546.6 EJP70369.1 - 0.2 11.3 2.0 0.34 10.5 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Secretin_N_2 PF07655.13 EJP70370.1 - 4.3 8.0 8.1 80 3.9 9.5 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain ABC_tran PF00005.27 EJP70372.1 - 3.6e-31 108.5 0.0 7.8e-31 107.4 0.1 1.5 2 0 0 2 2 1 1 ABC transporter AAA_22 PF13401.6 EJP70372.1 - 2e-05 24.9 0.5 7e-05 23.1 0.5 1.8 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 EJP70372.1 - 0.00027 21.1 0.3 0.00066 19.8 0.1 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 EJP70372.1 - 0.00039 20.5 0.1 0.0008 19.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EJP70372.1 - 0.00056 19.6 0.1 0.0014 18.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 EJP70372.1 - 0.0012 17.9 0.1 0.025 13.6 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.22 EJP70372.1 - 0.0012 18.0 0.4 0.022 14.0 0.4 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EJP70372.1 - 0.0014 19.0 0.6 0.0024 18.3 0.6 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EJP70372.1 - 0.002 18.6 0.1 0.22 11.9 0.1 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 EJP70372.1 - 0.0022 17.5 0.2 0.37 10.2 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJP70372.1 - 0.0078 16.1 0.4 0.11 12.3 0.2 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 EJP70372.1 - 0.0079 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.7 EJP70372.1 - 0.012 14.6 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain RsgA_GTPase PF03193.16 EJP70372.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 EJP70372.1 - 0.025 14.7 0.4 0.051 13.6 0.4 1.5 1 0 0 1 1 1 0 Dynamin family MeaB PF03308.16 EJP70372.1 - 0.029 13.3 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EJP70372.1 - 0.049 14.1 0.0 0.084 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EJP70372.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EJP70372.1 - 0.05 13.3 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EJP70372.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EJP70372.1 - 0.071 13.4 0.3 0.18 12.0 0.3 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EJP70372.1 - 0.076 12.9 1.4 0.45 10.4 1.4 2.1 1 1 0 1 1 1 0 NACHT domain Pox_A32 PF04665.12 EJP70372.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 EJP70372.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Fanconi_A PF03511.14 EJP70372.1 - 0.089 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein TrwB_AAD_bind PF10412.9 EJP70372.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 EJP70372.1 - 0.14 11.9 0.2 0.5 10.1 0.2 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase Ploopntkinase3 PF18751.1 EJP70372.1 - 0.15 12.0 0.0 0.68 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AIG1 PF04548.16 EJP70372.1 - 0.15 11.3 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 EJP70372.1 - 0.18 12.0 0.0 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EJP70372.1 - 0.21 11.4 0.1 0.45 10.2 0.1 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 EJP70372.1 - 0.24 11.1 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain M60-like_N PF17291.2 EJP70374.1 - 7e-11 42.0 0.0 1.8e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 N-terminal domain of M60-like peptidases Peptidase_M60 PF13402.6 EJP70374.1 - 1.3e-08 34.7 0.0 1.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like ABC_membrane PF00664.23 EJP70375.1 - 5.6e-85 285.3 36.8 1.7e-45 155.9 12.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP70375.1 - 1.4e-60 203.8 0.1 8.4e-29 100.8 0.0 3.4 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJP70375.1 - 8.8e-14 51.5 8.0 5.5e-06 26.0 2.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EJP70375.1 - 2e-07 31.1 0.0 0.018 15.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EJP70375.1 - 4.3e-07 29.6 2.3 0.0016 18.2 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP70375.1 - 5e-07 30.3 0.8 0.058 13.8 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EJP70375.1 - 2.1e-06 28.0 0.8 0.17 12.2 0.0 3.8 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 EJP70375.1 - 3.2e-06 26.2 0.2 0.032 13.0 0.0 3.3 3 0 0 3 3 3 1 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 EJP70375.1 - 0.00013 21.7 0.1 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 EJP70375.1 - 0.00014 21.6 0.6 0.14 11.8 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 EJP70375.1 - 0.00021 20.8 0.4 0.74 9.3 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_23 PF13476.6 EJP70375.1 - 0.00024 21.7 0.2 0.086 13.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 EJP70375.1 - 0.00034 20.4 0.2 0.44 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EJP70375.1 - 0.00041 20.2 1.1 1.3 8.8 0.1 3.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EJP70375.1 - 0.0006 19.4 0.8 1.2 8.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 EJP70375.1 - 0.011 15.0 0.1 3.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 EJP70375.1 - 0.014 15.6 0.1 4.8 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dala_Dala_lig_N PF01820.21 EJP70375.1 - 0.015 15.8 0.0 8.4 6.9 0.0 2.8 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus MMR_HSR1 PF01926.23 EJP70375.1 - 0.016 15.3 0.1 3 8.0 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EJP70375.1 - 0.018 15.6 0.0 8.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EJP70375.1 - 0.019 15.0 0.6 10 6.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EJP70375.1 - 0.019 15.2 1.6 2.8 8.2 0.3 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EJP70375.1 - 0.035 14.0 0.2 7 6.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_10 PF12846.7 EJP70375.1 - 0.087 11.7 0.6 0.23 10.3 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.17 EJP70375.1 - 0.093 12.8 1.3 1.1 9.3 0.1 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_33 PF13671.6 EJP70375.1 - 0.14 12.4 0.1 10 6.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EJP70375.1 - 0.15 11.8 0.1 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EJP70375.1 - 0.16 11.2 0.4 6.5 5.8 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain DUF815 PF05673.13 EJP70375.1 - 0.16 11.1 0.2 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) APS_kinase PF01583.20 EJP70375.1 - 0.25 11.2 0.8 18 5.2 0.0 2.7 3 0 0 3 3 2 0 Adenylylsulphate kinase PhoH PF02562.16 EJP70375.1 - 0.32 10.4 3.0 6.3 6.2 0.0 3.2 4 0 0 4 4 4 0 PhoH-like protein HNH_2 PF13391.6 EJP70376.1 - 0.00021 21.4 0.1 0.00043 20.3 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Fe_hyd_lg_C PF02906.14 EJP70377.1 - 1.1e-49 169.4 0.0 3.7e-49 167.6 0.0 1.9 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.7 EJP70378.1 - 4.2e-05 24.2 5.4 4.2e-05 24.2 5.4 3.1 2 1 1 3 3 3 1 SUZ domain Pkinase PF00069.25 EJP70381.1 - 5.4e-70 235.8 0.0 7.1e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70381.1 - 1.9e-31 109.3 0.0 2.6e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EJP70381.1 - 1.1e-14 54.9 0.2 5.5e-14 52.6 0.2 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EJP70381.1 - 3.6e-09 36.4 0.1 8.8e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 EJP70381.1 - 3.1e-08 33.8 0.0 6e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 EJP70381.1 - 0.0026 16.8 0.5 0.0043 16.1 0.1 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EJP70381.1 - 0.013 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EJP70381.1 - 0.022 14.4 0.2 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EJP70381.1 - 0.072 12.7 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP_sub_h PF10775.9 EJP70382.1 - 2.6e-23 81.8 0.9 3.6e-23 81.3 0.9 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h CDH-cyt PF16010.5 EJP70383.1 - 1.9e-19 70.1 0.4 3.6e-19 69.2 0.4 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 EJP70383.1 - 1.5e-07 31.1 6.7 2.7e-07 30.3 6.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Pkinase PF00069.25 EJP70384.1 - 5.7e-68 229.1 0.0 7e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70384.1 - 1.3e-31 109.8 0.0 1.7e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EJP70384.1 - 0.00035 21.2 0.1 0.00088 19.9 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EJP70384.1 - 0.0011 18.0 0.2 0.0015 17.6 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EJP70384.1 - 0.015 14.1 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EJP70384.1 - 0.071 12.4 0.1 0.18 11.1 0.0 1.7 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 EJP70384.1 - 0.09 12.7 0.3 2.7 7.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cyclin_N PF00134.23 EJP70385.1 - 4.3e-10 39.4 0.1 1.1e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain WD40 PF00400.32 EJP70386.1 - 8.4e-39 130.9 21.0 1.8e-09 38.1 1.6 7.9 7 1 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 EJP70386.1 - 8.4e-16 57.2 2.8 1.5e-15 56.4 2.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EJP70386.1 - 3e-13 49.9 1.7 0.061 13.6 0.0 5.9 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJP70386.1 - 0.0053 15.8 0.0 10 4.9 0.0 4.4 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EJP70386.1 - 0.026 13.8 0.0 0.48 9.7 0.0 2.7 3 1 0 3 3 3 0 WD40-like domain ABC_tran PF00005.27 EJP70387.1 - 5.8e-46 156.4 0.0 4.3e-27 95.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EJP70387.1 - 1.2e-19 71.0 11.6 2e-09 37.5 0.0 4.2 3 1 1 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 EJP70387.1 - 1.1e-08 34.8 1.4 0.0059 16.1 0.1 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EJP70387.1 - 1.6e-05 24.9 0.0 0.01 15.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EJP70387.1 - 1.8e-05 24.4 0.8 0.041 13.5 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJP70387.1 - 4e-05 23.3 0.3 0.43 10.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EJP70387.1 - 4.2e-05 24.0 0.2 0.095 13.1 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EJP70387.1 - 0.00045 20.3 0.4 0.52 10.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EJP70387.1 - 0.00047 20.1 2.3 5.8 6.6 0.1 4.1 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EJP70387.1 - 0.00057 20.2 1.6 1.6 9.0 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EJP70387.1 - 0.0012 19.4 0.7 0.17 12.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EJP70387.1 - 0.0013 19.2 0.1 4.1 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EJP70387.1 - 0.002 17.4 0.5 0.24 10.7 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 EJP70387.1 - 0.0029 17.4 1.1 2.6 7.7 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_33 PF13671.6 EJP70387.1 - 0.0031 17.7 0.1 2 8.6 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 EJP70387.1 - 0.0076 16.7 0.1 1.7 9.1 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EJP70387.1 - 0.0077 16.2 3.9 0.92 9.4 0.2 3.1 3 0 0 3 3 3 1 NACHT domain CbiA PF01656.23 EJP70387.1 - 0.011 15.8 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EJP70387.1 - 0.012 15.3 0.3 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJP70387.1 - 0.012 15.9 0.5 9.2 6.7 0.0 3.0 3 0 0 3 3 2 0 RNA helicase ATPase PF06745.13 EJP70387.1 - 0.019 14.3 0.4 5 6.4 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 EJP70387.1 - 0.02 14.6 5.4 3.2 7.4 2.4 3.1 2 1 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EJP70387.1 - 0.046 13.1 0.0 3.6 6.8 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DUF2075 PF09848.9 EJP70387.1 - 0.067 12.4 0.7 1.9 7.7 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 EJP70387.1 - 0.08 11.9 0.7 0.54 9.2 0.2 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EJP70387.1 - 0.16 12.0 5.1 0.17 11.9 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 EJP70387.1 - 0.16 11.9 0.8 4.7 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 EJP70387.1 - 0.26 10.7 2.1 13 5.1 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein NB-ARC PF00931.22 EJP70387.1 - 0.53 9.4 2.0 11 5.1 0.1 3.1 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.15 EJP70387.1 - 3.5 7.5 6.0 13 5.7 0.1 3.3 3 0 0 3 3 3 0 NTPase 2OG-FeII_Oxy_3 PF13640.6 EJP70388.1 - 9.4e-11 42.5 0.0 1.9e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3328 PF11807.8 EJP70389.1 - 1.6e-41 142.5 0.0 1.9e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 2-Hacid_dh_C PF02826.19 EJP70390.1 - 2e-39 134.8 0.0 5.3e-39 133.4 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJP70390.1 - 8.5e-19 67.5 0.0 9.6e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.18 EJP70390.1 - 0.0077 16.1 1.0 0.03 14.2 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 EJP70390.1 - 0.016 15.7 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Ciart PF15673.5 EJP70390.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor F420_oxidored PF03807.17 EJP70390.1 - 0.028 15.0 1.9 0.33 11.6 0.6 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EJP70390.1 - 0.11 12.0 0.3 0.31 10.6 0.0 1.9 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain LSM PF01423.22 EJP70391.1 - 1.5e-15 56.6 0.0 2e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain IU_nuc_hydro PF01156.19 EJP70392.1 - 1.2e-55 189.3 0.0 2e-55 188.5 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Spt20 PF12090.8 EJP70395.1 - 0.31 10.6 7.0 0.43 10.2 7.0 1.1 1 0 0 1 1 1 0 Spt20 family MAM33 PF02330.16 EJP70397.1 - 1.9e-73 246.9 0.2 2.4e-73 246.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Oxysterol_BP PF01237.18 EJP70398.1 - 2.9e-51 174.5 0.0 3.6e-49 167.6 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein PUF PF00806.19 EJP70399.1 - 7.6e-12 44.2 0.0 0.54 10.0 0.0 7.0 8 0 0 8 8 8 4 Pumilio-family RNA binding repeat AMP-binding PF00501.28 EJP70400.1 - 9.3e-86 288.0 0.1 1.2e-85 287.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP70400.1 - 9.4e-16 58.6 0.2 9.4e-16 58.6 0.2 2.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain PaaB PF06243.11 EJP70400.1 - 0.077 13.2 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 Phenylacetic acid degradation B Spt20 PF12090.8 EJP70402.1 - 3.3 7.3 13.7 6.9 6.2 13.7 1.5 1 0 0 1 1 1 0 Spt20 family OTT_1508_deam PF14441.6 EJP70403.1 - 8e-14 51.4 0.1 8e-14 51.4 0.1 2.3 2 0 0 2 2 2 1 OTT_1508-like deaminase zf-HIT PF04438.16 EJP70403.1 - 0.0047 16.8 12.7 0.0047 16.8 12.7 2.5 3 0 0 3 3 3 1 HIT zinc finger zf-MYND PF01753.18 EJP70403.1 - 0.091 12.9 23.1 0.028 14.5 18.3 2.6 2 0 0 2 2 2 0 MYND finger Pyridoxal_deC PF00282.19 EJP70404.1 - 4.8e-75 252.6 0.0 6.7e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EJP70404.1 - 0.00033 19.7 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EJP70404.1 - 0.0033 16.8 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Ras PF00071.22 EJP70406.1 - 5.1e-40 136.7 0.0 3.7e-26 91.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EJP70406.1 - 1.7e-12 47.6 0.1 3.5e-12 46.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP70406.1 - 0.00021 20.8 0.0 0.00093 18.7 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJP70406.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1117 PF06547.12 EJP70406.1 - 0.084 13.4 0.6 0.4 11.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) PRK PF00485.18 EJP70406.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EJP70406.1 - 0.15 12.4 0.1 0.22 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 EJP70406.1 - 0.23 11.0 0.1 3 7.3 0.0 2.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AMMECR1 PF01871.17 EJP70408.1 - 4.3e-45 153.3 0.0 5.2e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Cytomega_UL20A PF05984.12 EJP70409.1 - 0.011 16.0 0.1 0.012 15.9 0.1 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein WD40 PF00400.32 EJP70411.1 - 1.9e-57 189.9 22.3 2.3e-09 37.7 0.5 8.9 8 2 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP70411.1 - 5.7e-10 39.4 0.1 0.0016 18.7 0.0 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP70411.1 - 9.7e-05 21.2 0.5 0.0069 15.1 0.1 3.4 3 1 0 3 3 3 1 Nucleoporin Nup120/160 bZIP_2 PF07716.15 EJP70411.1 - 0.013 15.6 0.7 0.092 12.8 0.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper ADIP PF11559.8 EJP70411.1 - 0.054 13.6 0.9 0.09 12.9 0.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 EJP70411.1 - 0.065 13.3 0.6 0.19 11.9 0.4 1.8 2 0 0 2 2 2 0 bZIP transcription factor Nucleoporin_N PF08801.11 EJP70411.1 - 0.13 10.9 0.0 17 4.0 0.0 2.9 3 0 0 3 3 3 0 Nup133 N terminal like eIF2A PF08662.11 EJP70411.1 - 0.16 11.8 0.0 0.75 9.6 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Abhydrolase_1 PF00561.20 EJP70412.1 - 1.3e-08 34.8 0.0 1.2e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP70412.1 - 0.00051 19.4 0.0 0.0079 15.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP70412.1 - 0.0017 19.0 0.3 0.0025 18.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EJP70412.1 - 0.047 13.2 0.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cytadhesin_P30 PF07271.11 EJP70413.1 - 0.00061 19.4 0.3 0.001 18.7 0.3 1.3 1 0 0 1 1 1 1 Cytadhesin P30/P32 Shisa PF13908.6 EJP70413.1 - 0.0021 18.3 0.0 0.0021 18.3 0.0 2.5 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator TMIE PF16038.5 EJP70413.1 - 0.0025 17.6 0.4 0.0047 16.7 0.4 1.4 1 0 0 1 1 1 1 TMIE protein DUF4448 PF14610.6 EJP70413.1 - 0.0054 16.5 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3377 PF11857.8 EJP70413.1 - 0.029 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2681 PF10883.8 EJP70413.1 - 0.033 14.6 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EphA2_TM PF14575.6 EJP70413.1 - 0.053 14.4 0.0 0.095 13.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LST1 PF05083.13 EJP70413.1 - 0.083 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 LST-1 protein PqiA PF04403.13 EJP70413.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Paraquat-inducible protein A TMEM154 PF15102.6 EJP70413.1 - 0.36 10.7 0.0 0.36 10.7 0.0 2.8 2 1 1 3 3 3 0 TMEM154 protein family Cerato-platanin PF07249.12 EJP70414.1 - 0.0026 17.9 0.2 0.0059 16.7 0.2 1.7 2 0 0 2 2 2 1 Cerato-platanin Pkinase PF00069.25 EJP70415.1 - 5.8e-08 32.4 0.0 8.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EJP70415.1 - 9.7e-05 22.0 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EJP70415.1 - 0.00018 21.5 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EJP70415.1 - 0.00058 19.2 0.0 0.00072 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP70415.1 - 0.0045 16.4 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EJP70415.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family HTH_41 PF14502.6 EJP70415.1 - 0.037 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain EcKinase PF02958.20 EJP70415.1 - 0.042 13.1 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Seadorna_VP7 PF07387.11 EJP70415.1 - 0.075 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_16 PF00722.21 EJP70416.1 - 2.5e-09 36.9 0.1 3.6e-08 33.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EJP70416.1 - 7e-06 24.7 0.4 0.021 13.3 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Cellulase PF00150.18 EJP70417.1 - 1.1e-44 153.0 0.0 1.5e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAM117 PF15388.6 EJP70417.1 - 0.047 13.1 4.9 0.072 12.5 4.9 1.2 1 0 0 1 1 1 0 Protein Family FAM117 Glyco_hydro_1 PF00232.18 EJP70417.1 - 0.14 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 MSA-2c PF12238.8 EJP70417.1 - 0.18 11.8 2.7 0.27 11.2 2.7 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c MFS_1 PF07690.16 EJP70419.1 - 2.2e-24 86.1 20.4 2.8e-24 85.7 20.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 EJP70420.1 - 0.0079 16.6 2.7 0.0079 16.6 2.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EJP70420.1 - 0.035 14.2 5.4 0.42 10.7 3.5 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-RanBP PF00641.18 EJP70420.1 - 0.064 12.6 1.0 0.13 11.6 1.0 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-C2H2_4 PF13894.6 EJP70420.1 - 1.4 9.9 19.0 0.2 12.6 2.0 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger CAP59_mtransfer PF11735.8 EJP70422.1 - 3.7e-86 288.7 0.0 4.6e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PMT PF02366.18 EJP70423.1 - 2.3e-82 276.2 16.4 3.4e-82 275.7 16.4 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EJP70423.1 - 5.9e-66 221.9 6.7 5.9e-66 221.9 6.7 2.7 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EJP70423.1 - 1.1e-23 84.1 2.1 5.7e-23 81.7 0.5 1.7 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 EJP70423.1 - 0.00035 20.8 7.6 0.00035 20.8 7.6 2.8 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Fascin PF06268.13 EJP70423.1 - 0.067 13.4 0.0 0.8 9.9 0.0 2.3 2 0 0 2 2 2 0 Fascin domain Ribonuc_L-PSP PF01042.21 EJP70424.1 - 1.1e-38 131.9 0.0 1.4e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.32 EJP70425.1 - 7.5e-17 61.4 14.2 0.00056 20.7 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP70425.1 - 8.6e-08 32.4 0.0 0.05 13.9 0.0 4.5 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Diphthamide_syn PF01866.17 EJP70428.1 - 2.7e-86 289.7 0.0 3.3e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein FAD_binding_3 PF01494.19 EJP70429.1 - 5.5e-15 55.5 0.0 1.6e-14 54.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EJP70429.1 - 0.002 18.3 0.2 0.0046 17.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP70429.1 - 0.029 13.6 0.0 4.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP70429.1 - 0.032 13.8 0.6 0.72 9.4 0.6 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase PAS PF00989.25 EJP70429.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold K_oxygenase PF13434.6 EJP70429.1 - 0.18 10.9 0.0 8 5.5 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MutS_V PF00488.21 EJP70430.1 - 9.6e-67 224.7 0.4 2.6e-66 223.3 0.4 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EJP70430.1 - 1.3e-41 143.0 0.3 2.9e-41 141.8 0.3 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EJP70430.1 - 2.6e-32 111.4 0.2 5.4e-32 110.4 0.2 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EJP70430.1 - 2.4e-14 53.8 0.0 9.5e-14 51.8 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EJP70430.1 - 4.6e-13 49.3 0.5 1.2e-12 48.0 0.5 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 EJP70430.1 - 0.0058 16.2 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EJP70430.1 - 0.0076 16.8 1.6 0.051 14.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EJP70430.1 - 0.094 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EJP70430.1 - 0.67 9.7 7.8 0.14 12.0 0.2 2.6 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system 3HCDH_N PF02737.18 EJP70431.1 - 2.3e-28 99.3 0.0 3.4e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EJP70431.1 - 1.6e-13 51.1 0.0 3.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldl_recept_b PF00058.17 EJP70431.1 - 1.9e-05 25.0 1.1 2.9 8.4 0.0 4.6 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B NAD_Gly3P_dh_N PF01210.23 EJP70431.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3237 PF11578.8 EJP70431.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) GMC_oxred_N PF00732.19 EJP70432.1 - 4.6e-30 105.0 0.0 8.1e-30 104.2 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EJP70432.1 - 7.7e-17 62.2 0.2 1.4e-16 61.3 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EJP70432.1 - 0.00063 18.9 2.8 0.004 16.3 3.2 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EJP70432.1 - 0.00096 19.3 0.3 0.0029 17.8 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EJP70432.1 - 0.0012 18.1 0.2 0.0023 17.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EJP70432.1 - 0.0019 17.5 0.4 0.003 16.9 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EJP70432.1 - 0.0031 16.3 1.3 0.014 14.1 0.8 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EJP70432.1 - 0.0052 15.9 0.2 0.0083 15.2 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EJP70432.1 - 0.0061 15.8 0.2 0.047 12.9 1.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP70432.1 - 0.016 14.5 0.4 0.077 12.2 0.6 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJP70432.1 - 0.028 14.0 8.2 0.32 10.5 6.7 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EJP70432.1 - 0.27 10.3 1.2 0.4 9.7 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AMP-binding PF00501.28 EJP70433.1 - 7.8e-35 120.3 0.5 1.1e-34 119.8 0.5 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP70433.1 - 1.7e-11 45.0 1.0 1.8e-11 44.8 0.2 1.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EJP70435.1 - 1.6e-31 109.6 63.3 8.2e-21 74.3 31.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 EJP70435.1 - 0.0081 15.6 0.5 0.0081 15.6 0.5 2.5 2 0 0 2 2 2 1 ATP1G1/PLM/MAT8 family GD_AH_C PF04295.13 EJP70435.1 - 0.21 10.4 0.1 0.3 9.8 0.1 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus APH PF01636.23 EJP70436.1 - 6.1e-45 154.0 0.0 9.8e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EJP70436.1 - 0.00019 20.9 0.0 0.00063 19.1 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase Kdo PF06293.14 EJP70436.1 - 0.00043 19.7 0.0 0.001 18.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EJP70436.1 - 0.0011 18.7 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 EJP70436.1 - 0.0023 17.2 0.0 0.081 12.1 0.0 2.3 1 1 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.11 EJP70436.1 - 0.16 10.8 0.0 2.2 7.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) NMO PF03060.15 EJP70437.1 - 2e-23 83.3 0.4 2.9e-22 79.5 0.2 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 EJP70437.1 - 4.1e-05 22.7 0.0 7e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain MFS_1 PF07690.16 EJP70438.1 - 5.1e-33 114.4 17.8 5.1e-33 114.4 17.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EJP70438.1 - 9.4e-09 35.0 1.2 9.4e-09 35.0 1.2 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Trp_oprn_chp PF09534.10 EJP70438.1 - 0.00026 20.8 2.5 0.53 10.1 1.4 2.3 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Peptidase_M1 PF01433.20 EJP70438.1 - 0.17 11.4 0.3 0.93 9.0 0.3 2.0 1 1 0 1 1 1 0 Peptidase family M1 domain Peptidase_M43 PF05572.13 EJP70439.1 - 1.4e-14 54.3 0.2 3.9e-14 52.8 0.2 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EJP70439.1 - 1.6e-06 28.4 0.0 3.3e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EJP70439.1 - 0.0021 18.6 0.0 0.0069 16.9 0.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EJP70439.1 - 0.0051 16.7 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 Matrixin Exonuc_X-T_C PF08411.10 EJP70439.1 - 0.0078 15.4 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease C-terminal DUF4953 PF16313.5 EJP70439.1 - 0.014 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 EJP70439.1 - 0.06 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 EJP70439.1 - 0.23 10.0 0.2 0.3 9.6 0.2 1.1 1 0 0 1 1 1 0 Putative peptidase family Zn_clus PF00172.18 EJP70441.1 - 1.9e-06 27.9 9.6 3.1e-06 27.2 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP70441.1 - 0.019 14.0 0.1 0.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain DNAPolymera_Pol PF11590.8 EJP70441.1 - 6.6 6.7 5.5 1e+02 2.9 0.0 3.5 4 0 0 4 4 4 0 DNA polymerase catalytic subunit Pol Fungal_trans PF04082.18 EJP70442.1 - 5.7e-23 81.3 0.1 5.7e-23 81.3 0.1 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP70442.1 - 1.6e-05 24.9 1.5 4e-05 23.7 1.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrpF PF04303.13 EJP70443.1 - 3.8e-95 319.0 1.2 5.8e-88 295.3 0.4 2.0 2 0 0 2 2 2 2 PrpF protein EFP_N PF08207.12 EJP70443.1 - 0.032 14.3 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain VIT PF08487.10 EJP70444.1 - 6.3e-11 42.5 8.4 1e-09 38.6 5.3 3.3 3 1 0 3 3 3 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 EJP70444.1 - 5.6e-09 36.6 0.2 1.5e-08 35.2 0.2 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EJP70444.1 - 1.7e-08 34.9 0.7 1.1e-07 32.3 0.7 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EJP70444.1 - 1e-06 28.8 0.0 0.0023 17.9 0.0 2.5 1 1 1 2 2 2 2 von Willebrand factor type A domain VIT_2 PF13757.6 EJP70444.1 - 0.041 13.8 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 EJP70444.1 - 0.13 11.6 0.2 0.31 10.4 0.2 1.5 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Phos_pyr_kin PF08543.12 EJP70446.1 - 4.2e-18 65.6 0.4 9.4e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase DUF5047 PF16466.5 EJP70446.1 - 0.039 14.3 0.1 0.43 10.9 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5047) DUF3328 PF11807.8 EJP70447.1 - 2.6e-45 154.9 0.0 3.2e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EJP70448.1 - 6.7e-25 88.2 0.0 1.1e-24 87.4 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Transferase PF02458.15 EJP70449.1 - 1.2e-07 30.7 0.0 7.6e-05 21.5 0.0 2.9 2 1 0 2 2 2 2 Transferase family CM_2 PF01817.21 EJP70450.1 - 1e-06 29.0 0.0 2.2e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 Chorismate mutase type II ApoLp-III PF07464.11 EJP70452.1 - 0.00014 21.9 4.2 0.0072 16.4 0.9 2.1 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Alpha-E PF04168.12 EJP70452.1 - 0.0057 16.5 1.4 0.0071 16.2 1.4 1.1 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. DUF1539 PF07560.11 EJP70452.1 - 0.047 13.8 0.2 0.077 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) CSRNP_N PF16019.5 EJP70452.1 - 0.26 11.2 2.5 0.51 10.2 2.5 1.5 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4164 PF13747.6 EJP70452.1 - 2.9 8.2 11.4 0.23 11.8 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TipAS PF07739.13 EJP70452.1 - 3.3 8.3 10.4 6.1 7.4 0.7 2.2 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain RL PF17797.1 EJP70454.1 - 0.00081 19.3 1.8 34 4.5 0.1 5.3 5 0 0 5 5 5 1 RL domain PSII_Pbs31 PF18240.1 EJP70454.1 - 0.017 15.6 0.0 1.9 8.9 0.0 3.6 5 0 0 5 5 5 0 Photosystem II Psb31 protein NADH_dhqG_C PF09326.11 EJP70454.1 - 1.2 9.9 12.1 30 5.4 0.1 4.5 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal APG6_N PF17675.1 EJP70456.1 - 0.35 11.4 3.2 0.63 10.6 3.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Connexin PF00029.19 EJP70457.1 - 0.0027 17.5 0.6 0.0039 17.0 0.6 1.3 1 0 0 1 1 1 1 Connexin EOS1 PF12326.8 EJP70457.1 - 0.15 12.0 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein RNA_pol_Rpc4 PF05132.14 EJP70457.1 - 4.2 7.8 12.7 0.32 11.4 8.0 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 SR-25 PF10500.9 EJP70457.1 - 6.2 6.4 37.2 9.3 5.8 37.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Coilin_N PF15862.5 EJP70457.1 - 8.8 6.1 23.1 18 5.1 23.1 1.4 1 0 0 1 1 1 0 Coilin N-terminus 7TM_GPCR_Srv PF10323.9 EJP70459.1 - 0.017 14.5 0.0 0.064 12.6 0.0 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv FAD_binding_4 PF01565.23 EJP70460.1 - 6.1e-24 84.3 0.0 9.3e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 EJP70460.1 - 8.4e-15 55.1 0.0 1.4e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DUF997 PF06196.12 EJP70460.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF997) adh_short PF00106.25 EJP70461.1 - 3e-24 85.6 0.0 6.6e-24 84.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJP70461.1 - 2.6e-16 59.9 0.0 6.4e-16 58.6 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase IDO PF01231.18 EJP70461.1 - 2.3e-08 33.3 1.5 1.6e-07 30.5 1.5 2.0 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Zn_clus PF00172.18 EJP70462.1 - 0.01 16.0 9.6 0.018 15.2 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_31 PF13847.6 EJP70463.1 - 9.2e-08 32.0 0.0 1.5e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP70463.1 - 4.2e-07 30.6 0.0 1e-06 29.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJP70463.1 - 2.8e-05 24.8 0.0 8.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EJP70463.1 - 6.9e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EJP70463.1 - 8.4e-05 22.5 0.0 0.00023 21.0 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJP70463.1 - 0.00012 22.7 0.0 0.00024 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EJP70463.1 - 0.0005 19.6 0.0 0.00098 18.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 EJP70463.1 - 0.00064 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EJP70463.1 - 0.002 18.3 0.0 0.0037 17.4 0.0 1.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EJP70463.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 EJP70463.1 - 0.054 13.2 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 EJP70463.1 - 0.057 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 EJP70463.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MFS_1 PF07690.16 EJP70464.1 - 4.1e-41 141.1 37.5 5.4e-41 140.7 37.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP70464.1 - 6.4e-12 45.1 7.4 6.4e-12 45.1 7.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP70464.1 - 1.2e-07 30.6 7.3 2.6e-07 29.5 3.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EJP70464.1 - 0.00093 17.7 2.1 0.0017 16.8 1.1 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Tmemb_18A PF09771.9 EJP70464.1 - 0.16 12.4 0.3 0.51 10.7 0.3 1.8 1 0 0 1 1 1 0 Transmembrane protein 188 DUF5087 PF17006.5 EJP70464.1 - 0.64 9.5 2.4 1.1 8.8 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) Oxidored_molyb PF00174.19 EJP70465.1 - 2.5e-45 154.2 0.0 6.5e-45 152.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EJP70465.1 - 3.5e-20 72.4 2.7 6.4e-20 71.6 2.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Glyco_hydro_127 PF07944.12 EJP70465.1 - 0.15 10.5 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Fungal_trans_2 PF11951.8 EJP70466.1 - 1.1e-13 50.7 4.0 1.9e-13 50.0 4.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3HCDH_N PF02737.18 EJP70467.1 - 5e-40 137.3 0.0 7.1e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EJP70467.1 - 2.4e-08 34.5 0.0 4.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 EJP70467.1 - 0.00041 19.8 0.0 0.00075 18.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EJP70467.1 - 0.02 15.4 0.0 0.12 13.0 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EJP70467.1 - 0.032 14.4 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.16 EJP70468.1 - 2.6e-36 125.3 25.1 2.6e-36 125.3 25.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EJP70468.1 - 0.00055 19.3 6.6 0.00055 19.3 6.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ABM PF03992.16 EJP70470.1 - 4.1e-05 23.6 0.3 0.00019 21.5 0.1 2.1 3 0 0 3 3 3 1 Antibiotic biosynthesis monooxygenase Polysacc_deac_1 PF01522.21 EJP70471.1 - 4.5e-21 75.0 0.0 6.7e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 EJP70471.1 - 0.0011 18.1 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase GFRP PF06399.13 EJP70471.1 - 0.025 14.5 0.1 0.28 11.1 0.0 2.6 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) AAA_33 PF13671.6 EJP70472.1 - 4.3e-09 36.7 0.0 7.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EJP70472.1 - 4.8e-08 32.5 0.0 9.3e-08 31.6 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EJP70472.1 - 0.0004 20.9 0.0 0.00075 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EJP70472.1 - 0.02 14.8 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase Zn_clus PF00172.18 EJP70475.1 - 2.2e-08 34.0 7.0 4.9e-08 33.0 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP70475.1 - 0.048 12.5 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain WD40 PF00400.32 EJP70476.1 - 3.4e-13 49.8 10.6 0.011 16.6 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP70476.1 - 1.7e-06 28.3 1.2 0.0067 16.7 0.2 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJP70476.1 - 1.3e-05 24.1 1.8 2.2e-05 23.3 0.2 2.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EJP70476.1 - 0.017 14.1 0.4 0.044 12.7 0.1 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HA2 PF04408.23 EJP70477.1 - 3.5e-22 78.7 0.0 3.5e-22 78.7 0.0 3.1 4 0 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EJP70477.1 - 4.8e-20 71.7 0.0 1.5e-19 70.1 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EJP70477.1 - 1.9e-14 53.9 0.0 4.4e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP70477.1 - 9.5e-10 38.5 0.1 1.7e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJP70477.1 - 2.9e-06 27.6 0.1 7.9e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJP70477.1 - 0.00025 20.8 0.2 0.00099 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EJP70477.1 - 0.00025 21.4 0.2 0.00063 20.1 0.2 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EJP70477.1 - 0.0021 17.4 0.0 0.0021 17.4 0.0 2.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 EJP70477.1 - 0.0064 16.5 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ATPase PF06745.13 EJP70477.1 - 0.0064 15.9 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 KaiC SRP54 PF00448.22 EJP70477.1 - 0.008 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 EJP70477.1 - 0.012 15.6 0.4 0.31 11.0 0.4 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 EJP70477.1 - 0.02 14.0 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EJP70477.1 - 0.03 14.0 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJP70477.1 - 0.044 14.3 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter GAD PF02938.14 EJP70477.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 GAD domain AAA_14 PF13173.6 EJP70477.1 - 0.054 13.5 0.4 0.7 9.9 0.4 2.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EJP70477.1 - 0.062 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 EJP70477.1 - 0.063 13.4 0.0 0.38 10.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain PAX PF00292.18 EJP70477.1 - 0.067 13.1 0.0 13 5.7 0.0 2.8 2 0 0 2 2 2 0 'Paired box' domain AAA_29 PF13555.6 EJP70477.1 - 0.2 11.4 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EJP70477.1 - 0.63 10.5 0.0 0.63 10.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain Trp_oprn_chp PF09534.10 EJP70477.1 - 7.1 6.4 9.4 11 5.7 2.0 2.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Hep_59 PF07052.11 EJP70478.1 - 2.3e-07 31.5 0.2 2.3e-07 31.5 0.2 2.8 2 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 zf-UDP PF14569.6 EJP70479.1 - 0.17 12.0 4.6 0.36 11.0 4.6 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-B_box PF00643.24 EJP70479.1 - 3.3 8.0 11.3 1.8 8.8 6.9 2.7 1 1 0 1 1 1 0 B-box zinc finger Ribosomal_S27 PF01599.19 EJP70479.1 - 4.3 7.6 10.0 0.38 11.0 5.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S27a Lactamase_B_3 PF13483.6 EJP70484.1 - 0.005 16.7 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EF-hand_1 PF00036.32 EJP70485.1 - 1.2e-22 77.7 6.2 4.4e-06 25.9 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 EJP70485.1 - 6.9e-21 74.5 5.3 6.5e-08 32.9 0.0 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EJP70485.1 - 7.3e-20 69.1 5.8 0.00022 20.9 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EJP70485.1 - 3e-17 62.2 8.9 1.2e-08 34.6 0.1 4.9 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 EJP70485.1 - 3.5e-13 48.4 3.5 0.00079 18.8 0.2 4.3 4 0 0 4 4 4 3 EF hand Ndc1_Nup PF09531.10 EJP70485.1 - 0.044 12.5 1.2 0.044 12.5 1.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EF-hand_9 PF14658.6 EJP70485.1 - 0.16 12.3 2.6 1 9.7 0.0 3.2 4 1 0 4 4 4 0 EF-hand domain SPX PF03105.19 EJP70485.1 - 1.8 8.4 11.1 2.3 8.1 11.1 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 EJP70485.1 - 4.7 6.3 14.2 6.2 5.9 14.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 EJP70485.1 - 7.3 6.5 14.9 10 6.0 14.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ChaC PF04752.12 EJP70486.1 - 2.2e-36 125.6 0.0 3.4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein Kdo PF06293.14 EJP70486.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 EJP70486.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 EJP70486.1 - 0.065 13.2 0.0 5.4 6.9 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP70486.1 - 0.067 12.8 0.0 7.7 6.0 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 EJP70486.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain RRM_1 PF00076.22 EJP70487.1 - 2.5e-22 78.5 0.0 3.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP70487.1 - 0.00065 19.8 0.0 0.0014 18.7 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif PAP_PilO PF06864.12 EJP70487.1 - 0.032 13.1 0.1 0.032 13.1 0.1 1.4 2 0 0 2 2 2 0 Pilin accessory protein (PilO) RRM_occluded PF16842.5 EJP70487.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif HpcH_HpaI PF03328.14 EJP70488.1 - 9.1e-38 129.6 0.3 5.2e-20 71.5 0.2 2.8 2 1 1 3 3 3 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EJP70488.1 - 6.4e-14 51.8 0.0 6.7e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.12 EJP70489.1 - 2.1e-42 144.4 3.9 2.6e-42 144.1 3.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) SKG6 PF08693.10 EJP70490.1 - 0.0042 16.4 3.4 0.01 15.2 3.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4690 PF15756.5 EJP70490.1 - 0.0052 17.4 0.0 0.022 15.3 0.0 2.1 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Gram_pos_anchor PF00746.21 EJP70490.1 - 0.036 14.0 3.1 0.075 13.0 3.1 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF726 PF05277.12 EJP70491.1 - 3.8e-126 420.7 2.6 5.5e-126 420.1 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fcf1 PF04900.12 EJP70492.1 - 2.1e-30 105.0 0.1 3.8e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 EJP70492.1 - 0.00093 17.6 13.7 0.0015 16.9 13.7 1.3 1 0 0 1 1 1 1 CDC45-like protein Myf5 PF12232.8 EJP70492.1 - 0.17 12.6 0.0 0.44 11.3 0.0 1.7 1 0 0 1 1 1 0 Myogenic determination factor 5 Presenilin PF01080.17 EJP70492.1 - 2.8 6.6 8.6 3.8 6.2 8.6 1.1 1 0 0 1 1 1 0 Presenilin SpoIIE PF07228.12 EJP70494.1 - 2.2e-05 24.5 0.0 6.2e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EJP70494.1 - 0.0003 20.5 0.1 0.00052 19.7 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EJP70494.1 - 0.00074 19.2 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF5641 PF18701.1 EJP70494.1 - 0.08 13.1 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5641) APOC4 PF15119.6 EJP70494.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein C4 PH PF00169.29 EJP70495.1 - 2.6e-07 31.1 0.0 1.9e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 EJP70495.1 - 0.0019 18.5 0.0 0.0058 17.0 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Peptidase_S9_N PF02897.15 EJP70495.1 - 0.028 13.2 0.1 0.04 12.7 0.1 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Pkinase PF00069.25 EJP70496.1 - 2.2e-59 201.0 0.0 4.3e-59 200.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70496.1 - 3.4e-29 101.9 0.0 5.7e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EJP70496.1 - 9.3e-11 41.9 0.1 2.3e-08 34.2 0.0 3.1 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 EJP70496.1 - 0.0064 16.8 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EJP70496.1 - 0.013 14.8 0.7 0.11 11.8 0.1 2.6 2 1 0 2 2 2 0 Kinase-like RIO1 PF01163.22 EJP70496.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EJP70496.1 - 0.063 12.0 0.2 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EJP70496.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4658 PF15555.6 EJP70496.1 - 0.18 11.9 2.8 0.37 10.9 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Pox_ser-thr_kin PF05445.11 EJP70496.1 - 0.22 10.4 0.1 0.34 9.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EJP70496.1 - 0.4 10.5 3.1 0.47 10.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DZR PF12773.7 EJP70497.1 - 3.1 7.9 11.8 2.4 8.3 7.2 2.5 1 1 1 2 2 2 0 Double zinc ribbon STT3 PF02516.14 EJP70498.1 - 5.5e-142 474.1 35.4 7.2e-137 457.3 33.5 2.3 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.12 EJP70499.1 - 2.1e-22 79.2 0.2 2.4e-22 79.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain ABC_trans_N PF14510.6 EJP70499.1 - 0.057 14.0 0.2 0.077 13.6 0.2 1.2 1 0 0 1 1 1 0 ABC-transporter N-terminal VIT1 PF01988.19 EJP70499.1 - 0.17 11.8 0.1 0.19 11.6 0.1 1.1 1 0 0 1 1 1 0 VIT family WD40 PF00400.32 EJP70500.1 - 7.3e-08 33.0 10.0 0.79 10.7 1.6 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat RRM_1 PF00076.22 EJP70501.1 - 8.5e-17 60.7 0.0 1.3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EJP70501.1 - 0.00028 21.4 22.1 0.00028 21.4 22.1 3.7 3 1 0 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 MarR PF01047.22 EJP70502.1 - 0.039 13.9 0.2 0.9 9.5 0.0 2.6 2 0 0 2 2 2 0 MarR family EcsC PF12787.7 EJP70502.1 - 0.07 12.8 0.1 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 EcsC protein family Cnd1 PF12717.7 EJP70502.1 - 0.13 12.3 0.0 0.63 10.1 0.0 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DEAD PF00270.29 EJP70503.1 - 5.2e-49 166.4 0.0 1.1e-48 165.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP70503.1 - 9.2e-28 96.8 0.0 6.4e-27 94.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP70503.1 - 0.00022 21.3 0.0 0.0005 20.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 EJP70503.1 - 0.015 15.8 2.6 0.015 15.8 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) UTP25 PF06862.12 EJP70503.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Mitoc_mL59 PF18126.1 EJP70504.1 - 1.3e-40 138.7 1.4 1.5e-40 138.5 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 EJP70505.1 - 1.1e-17 63.5 1.0 1.6e-17 62.9 1.0 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EJP70505.1 - 4.1e-11 42.8 0.1 7.3e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain 14-3-3 PF00244.20 EJP70506.1 - 5.4e-101 336.7 8.6 3.5e-90 301.4 1.8 2.0 1 1 1 2 2 2 2 14-3-3 protein IATP PF04568.12 EJP70507.1 - 1.6e-37 127.9 2.8 1.8e-37 127.7 2.8 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF2205 PF10224.9 EJP70507.1 - 0.073 13.1 4.7 0.096 12.7 4.7 1.2 1 0 0 1 1 1 0 Short coiled-coil protein XhlA PF10779.9 EJP70507.1 - 0.12 12.6 2.0 0.17 12.1 2.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF1003 PF06210.11 EJP70507.1 - 1.4 9.1 4.1 2.3 8.3 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) Nsp1_C PF05064.13 EJP70508.1 - 1.9e-38 130.9 3.0 2.5e-38 130.5 1.6 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EJP70508.1 - 8.4e-15 55.4 167.8 5.8e-11 43.1 25.0 7.6 1 1 6 7 7 7 5 Nucleoporin FG repeat region ERM PF00769.19 EJP70508.1 - 0.08 12.8 8.1 0.12 12.2 8.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4201 PF13870.6 EJP70508.1 - 0.13 11.9 5.9 2.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.12 EJP70508.1 - 0.17 11.9 0.7 1.3 9.1 0.1 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAS20 PF02064.15 EJP70508.1 - 0.92 9.6 2.8 1.9 8.6 2.8 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor V-SNARE PF05008.15 EJP70508.1 - 1.3 9.5 9.9 1.7 9.1 1.1 3.1 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus BRE1 PF08647.11 EJP70508.1 - 1.3 9.1 7.7 1.1 9.3 2.2 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HIP1_clath_bdg PF16515.5 EJP70508.1 - 1.6 9.4 8.0 8.4 7.1 0.3 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EJP70508.1 - 1.8 8.6 5.5 17 5.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 EJP70508.1 - 2.8 6.5 8.8 4.5 5.8 2.1 2.0 1 1 1 2 2 2 0 AAA domain Laminin_II PF06009.12 EJP70508.1 - 3.9 7.5 6.6 18 5.3 0.4 2.4 2 0 0 2 2 2 0 Laminin Domain II Uso1_p115_C PF04871.13 EJP70508.1 - 5.8 7.3 10.4 0.98 9.8 4.3 2.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region MIP-T3_C PF17749.1 EJP70508.1 - 7.4 6.5 8.3 8.1 6.4 0.1 3.0 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF724 PF05266.14 EJP70508.1 - 9 6.1 10.2 3.2 7.5 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF5102 PF17104.5 EJP70509.1 - 8.2e-112 374.0 1.4 8.2e-112 374.0 1.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF5102) DUF4521 PF15021.6 EJP70509.1 - 0.89 9.4 5.7 1.4 8.8 5.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4521) eIF2_C PF09173.11 EJP70510.1 - 2.6e-34 117.3 0.5 6e-34 116.2 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EJP70510.1 - 4.1e-22 78.7 0.5 3.7e-21 75.6 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EJP70510.1 - 8.3e-10 38.9 0.3 1.9e-09 37.7 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EJP70510.1 - 0.0081 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJP70510.1 - 0.012 15.5 0.2 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EJP70510.1 - 0.013 15.5 0.7 0.048 13.7 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 EJP70510.1 - 0.076 12.2 0.1 0.15 11.2 0.0 1.4 2 0 0 2 2 2 0 G-protein alpha subunit Glyco_trans_2_3 PF13632.6 EJP70511.1 - 6.6e-20 71.9 1.0 6.6e-20 71.9 1.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 MASE5 PF17178.4 EJP70511.1 - 0.2 11.5 4.7 9.4 6.0 0.0 3.1 3 0 0 3 3 3 0 Membrane-associated sensor Anp1 PF03452.14 EJP70512.1 - 1.8e-109 365.2 0.0 2.4e-109 364.8 0.0 1.2 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EJP70512.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Chi-conotoxin PF16981.5 EJP70512.1 - 0.25 11.6 0.3 0.7 10.2 0.3 1.7 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily UQ_con PF00179.26 EJP70513.1 - 4.5e-33 113.9 0.0 6.9e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP70513.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 EJP70513.1 - 0.22 11.4 0.8 0.48 10.3 0.0 1.9 3 0 0 3 3 3 0 UEV domain SelP_N PF04592.14 EJP70513.1 - 2.1 7.7 7.7 4 6.8 7.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SRR1 PF07985.12 EJP70514.1 - 0.00081 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 SRR1 PRA1 PF03208.19 EJP70515.1 - 2.4e-35 121.2 0.3 3.1e-35 120.9 0.3 1.1 1 0 0 1 1 1 1 PRA1 family protein Renin_r PF07850.14 EJP70515.1 - 0.07 13.7 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 Renin receptor-like protein ELMO_CED12 PF04727.13 EJP70516.1 - 1.7e-46 158.6 0.1 3.2e-46 157.6 0.1 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 EJP70516.1 - 8.9e-41 139.6 0.0 1.8e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EJP70516.1 - 2.3e-12 47.1 0.0 4.9e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Cutinase PF01083.22 EJP70517.1 - 5.6e-42 143.7 0.6 6.5e-42 143.5 0.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EJP70517.1 - 1.6e-05 24.6 0.2 2.3e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EJP70517.1 - 0.0002 21.3 0.0 0.00099 19.0 0.0 1.8 1 1 1 2 2 2 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 EJP70517.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 EJP70517.1 - 0.062 13.1 0.0 0.091 12.5 0.0 1.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EJP70517.1 - 0.11 13.1 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 EJP70517.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Homeodomain PF00046.29 EJP70518.1 - 9.6e-14 51.0 2.5 1.9e-13 50.0 2.5 1.5 1 0 0 1 1 1 1 Homeodomain NAD_kinase PF01513.21 EJP70519.1 - 1.1e-80 271.0 0.0 1.5e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 EJP70520.1 - 3.1e-14 53.6 0.0 5.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EJP70520.1 - 0.021 14.8 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PTPA PF03095.15 EJP70521.1 - 2.3e-110 368.8 0.0 2.7e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Carb_kinase PF01256.17 EJP70523.1 - 7.7e-56 189.3 0.2 1.1e-55 188.8 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 EJP70523.1 - 0.00021 20.8 0.5 0.0006 19.3 0.1 1.8 1 1 1 2 2 2 1 Hydroxyethylthiazole kinase family ATP-synt_ab PF00006.25 EJP70524.1 - 1.5e-73 247.0 0.0 2.2e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EJP70524.1 - 3.2e-48 163.2 0.4 5.5e-48 162.4 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EJP70524.1 - 3.5e-15 56.3 2.8 8.4e-15 55.1 2.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RbcS PF12338.8 EJP70524.1 - 6.5 7.0 6.1 1.7 8.9 0.4 2.7 3 0 0 3 3 3 0 Ribulose-1,5-bisphosphate carboxylase small subunit Ribosomal_L5_C PF00673.21 EJP70525.1 - 2.8e-22 78.7 0.0 4.1e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EJP70525.1 - 5e-21 74.8 0.9 9.8e-21 73.9 0.0 2.0 3 0 0 3 3 3 1 Ribosomal protein L5 LSM PF01423.22 EJP70526.1 - 1.2e-16 60.1 0.0 1.6e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DnaJ PF00226.31 EJP70527.1 - 3.4e-20 71.9 0.8 5.3e-20 71.3 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EJP70527.1 - 0.036 14.4 1.5 0.053 13.8 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 EJP70527.1 - 0.25 11.5 5.9 0.42 10.8 5.9 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PITH PF06201.13 EJP70528.1 - 1.7e-36 125.7 0.0 2.5e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EJP70528.1 - 3.5e-10 39.8 0.0 6.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EJP70528.1 - 3e-05 23.5 0.1 6.5e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family HyaE PF07449.11 EJP70528.1 - 0.035 14.1 0.0 0.094 12.7 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 EJP70528.1 - 0.17 12.4 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain CorA PF01544.18 EJP70529.1 - 6.3e-12 45.4 3.3 5.6e-11 42.3 0.2 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF4231 PF14015.6 EJP70529.1 - 0.12 12.8 0.4 0.3 11.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) RhoGAP PF00620.27 EJP70531.1 - 2.2e-45 154.2 0.6 4.8e-45 153.1 0.6 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EJP70531.1 - 4.6e-12 46.4 0.0 1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.24 EJP70531.1 - 0.064 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 PX domain RBD-FIP PF09457.10 EJP70531.1 - 0.73 9.8 2.2 38 4.3 0.0 2.5 2 0 0 2 2 2 0 FIP domain Zn_clus PF00172.18 EJP70532.1 - 0.00034 20.7 13.0 0.00057 20.0 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP70532.1 - 0.0048 16.0 0.0 0.015 14.3 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribonuc_P_40 PF08584.11 EJP70532.1 - 0.4 9.9 2.8 0.73 9.1 2.8 1.4 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit PAT1 PF09770.9 EJP70532.1 - 3.9 5.6 19.2 7.3 4.7 19.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 EJP70532.1 - 8.4 6.1 6.9 16 5.2 6.9 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain WLM PF08325.10 EJP70534.1 - 1.7e-29 103.3 0.2 5.3e-29 101.6 0.1 1.9 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 EJP70534.1 - 2.3e-05 24.5 1.7 4.6e-05 23.6 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 EJP70534.1 - 0.0092 15.3 2.1 0.025 13.9 2.1 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.7 EJP70534.1 - 0.45 10.6 9.1 0.85 9.7 9.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon Sulfate_transp PF00916.20 EJP70535.1 - 8.1e-111 370.4 19.9 1e-110 370.1 19.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EJP70535.1 - 6.9e-08 32.1 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EJP70535.1 - 0.00046 20.6 4.6 0.00046 20.6 4.6 2.9 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily RabGAP-TBC PF00566.18 EJP70536.1 - 5.9e-29 101.3 0.0 2.3e-24 86.3 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain HlyIII PF03006.20 EJP70537.1 - 7.5e-59 199.2 21.4 9.2e-59 198.9 21.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2894 PF11445.8 EJP70537.1 - 0.079 13.4 1.2 0.13 12.7 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) FmiP_Thoc5 PF09766.9 EJP70538.1 - 7.8e-31 107.7 11.6 1.2e-30 107.1 11.6 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 EJP70538.1 - 0.018 15.1 4.6 0.018 15.1 4.6 2.0 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus AROS PF15684.5 EJP70538.1 - 0.64 10.6 6.8 0.23 12.0 0.5 2.2 2 1 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 YabA PF06156.13 EJP70538.1 - 1.8 9.3 7.4 7.2 7.3 0.2 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Casc1_N PF15927.5 EJP70538.1 - 1.9 8.2 16.4 0.11 12.1 9.5 2.2 2 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DUF3958 PF13125.6 EJP70538.1 - 2.5 8.3 15.1 1.6 8.9 0.2 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3958) NPL PF17800.1 EJP70539.1 - 1.4e-34 118.8 2.5 1.4e-34 118.8 2.5 2.6 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 EJP70539.1 - 2.3e-30 104.8 0.2 7.8e-30 103.1 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 EJP70540.1 - 5.4e-42 144.0 0.0 1.9e-32 112.7 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70540.1 - 3e-17 62.8 0.0 2.2e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJP70540.1 - 0.00021 20.4 2.0 0.00055 19.0 2.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EJP70540.1 - 0.00026 21.0 0.8 0.0014 18.6 0.6 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP70540.1 - 0.025 13.9 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 EJP70540.1 - 0.083 11.8 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 EJP70541.1 - 9e-36 123.6 0.0 1.8e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70541.1 - 1.5e-12 47.4 0.0 6.4e-10 38.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EJP70541.1 - 0.00034 20.6 0.0 0.00073 19.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EJP70541.1 - 0.0035 16.7 0.0 0.5 9.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Glyco_hydro_38N PF01074.22 EJP70542.1 - 2.9e-88 296.0 0.1 4.3e-88 295.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EJP70542.1 - 1.3e-51 175.7 0.1 2.1e-51 175.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EJP70542.1 - 8.1e-29 99.6 0.1 2e-28 98.4 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EJP70542.1 - 4.2e-11 42.8 0.0 1.1e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EJP70542.1 - 0.11 11.7 0.0 0.61 9.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 MutS_V PF00488.21 EJP70543.1 - 1.7e-70 236.9 0.0 3.2e-70 236.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EJP70543.1 - 1.1e-47 162.8 4.9 1.8e-47 162.0 4.9 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EJP70543.1 - 4.5e-20 72.0 0.0 1.2e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EJP70543.1 - 2.7e-10 40.7 0.0 7e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 EJP70543.1 - 0.095 12.5 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L10 PF00466.20 EJP70544.1 - 1.1e-24 86.4 0.1 3.7e-24 84.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EJP70544.1 - 4.7e-22 77.8 0.0 9.2e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EJP70544.1 - 2.4e-17 63.3 3.7 2.4e-17 63.3 3.7 1.6 2 0 0 2 2 2 1 60s Acidic ribosomal protein CPSF_A PF03178.15 EJP70545.1 - 0.062 12.6 0.0 0.96 8.7 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region DnaJ_C PF01556.18 EJP70546.1 - 1.6e-34 119.2 0.1 2.1e-34 118.8 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJP70546.1 - 7.8e-26 90.0 1.8 1.6e-25 89.0 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EJP70546.1 - 2.2e-14 53.6 17.1 3.7e-14 52.8 17.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 EJP70546.1 - 0.058 13.4 7.4 0.18 11.9 6.7 2.1 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c AAA_30 PF13604.6 EJP70546.1 - 0.15 11.7 0.1 0.39 10.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain zinc-ribbons_6 PF07191.12 EJP70546.1 - 0.39 10.7 8.3 4.6 7.3 2.1 2.3 2 0 0 2 2 2 0 zinc-ribbons Anti-TRAP PF15777.5 EJP70546.1 - 0.46 10.5 15.4 0.75 9.8 2.3 3.0 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EJP70546.1 - 0.6 10.1 9.8 0.45 10.6 2.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Paired_CXXCH_1 PF09699.10 EJP70546.1 - 0.65 9.8 4.1 14 5.5 0.4 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 EJP70546.1 - 2.1 8.8 10.7 4.3 7.9 3.4 2.5 1 1 1 2 2 2 0 Cytochrome c3 Cytochrom_C PF00034.21 EJP70546.1 - 2.2 9.5 5.2 12 7.1 0.5 3.0 3 0 0 3 3 2 0 Cytochrome c DUF2614 PF11023.8 EJP70546.1 - 3.5 7.7 4.8 5 7.3 0.5 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 EJP70546.1 - 4.9 7.3 13.5 3.4 7.9 2.0 3.7 2 1 0 2 2 2 0 Zinc ribbon domain Cytochrome_CBB3 PF13442.6 EJP70546.1 - 5 7.5 12.8 2.5 8.5 3.0 3.2 2 1 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III CAP_GLY PF01302.25 EJP70547.1 - 7.2e-17 61.2 2.0 1.1e-16 60.5 2.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Med4 PF10018.9 EJP70547.1 - 0.0015 18.2 1.7 0.0015 18.2 1.7 3.2 3 0 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 Spc7 PF08317.11 EJP70547.1 - 0.0031 16.4 26.3 0.068 12.0 4.5 3.3 2 1 2 4 4 4 4 Spc7 kinetochore protein Glutaredoxin2_C PF04399.13 EJP70547.1 - 0.022 14.6 6.4 0.26 11.1 0.3 2.7 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain DP PF08781.10 EJP70547.1 - 0.035 14.0 0.7 0.035 14.0 0.7 2.3 3 0 0 3 3 2 0 Transcription factor DP YlbD_coat PF14071.6 EJP70547.1 - 0.11 12.8 3.3 2.8 8.2 0.2 2.6 2 0 0 2 2 2 0 Putative coat protein Sec2p PF06428.11 EJP70547.1 - 0.18 11.8 17.6 0.18 11.8 1.1 4.2 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p PEARLI-4 PF05278.12 EJP70547.1 - 0.27 10.8 9.9 0.99 8.9 4.0 2.6 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) MscS_porin PF12795.7 EJP70547.1 - 0.56 9.7 25.8 0.064 12.8 5.2 3.4 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Exonuc_VII_S PF02609.16 EJP70547.1 - 0.81 9.8 13.3 0.033 14.3 5.1 3.0 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF1970 PF09301.10 EJP70547.1 - 0.87 9.9 4.3 6 7.2 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) DUF812 PF05667.11 EJP70547.1 - 0.92 8.3 26.9 0.57 9.0 18.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 EJP70547.1 - 0.94 9.5 30.0 0.2 11.7 11.4 3.9 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EJP70547.1 - 1.1 9.4 25.6 4.3 7.4 1.1 3.5 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 EJP70547.1 - 1.2 9.5 18.3 2.2 8.7 0.3 4.4 4 1 0 4 4 4 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 EJP70547.1 - 1.4 9.0 16.4 2.9 8.0 2.8 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 EJP70547.1 - 1.6 9.2 23.6 4.5 7.7 0.0 4.9 4 1 1 5 5 5 0 Csm1 N-terminal domain Filament PF00038.21 EJP70547.1 - 1.6 8.2 31.3 5.2 6.6 19.7 2.9 2 1 0 2 2 2 0 Intermediate filament protein DivIC PF04977.15 EJP70547.1 - 1.8 8.4 23.1 0.084 12.7 1.9 5.3 5 1 1 6 6 6 0 Septum formation initiator Phage_GP20 PF06810.11 EJP70547.1 - 2.3 8.0 23.5 0.075 12.8 5.8 3.7 2 2 1 4 4 4 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 EJP70547.1 - 2.5 8.6 8.3 8.8 6.9 0.2 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 EJP70547.1 - 2.5 8.1 33.9 0.39 10.7 6.5 5.2 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 EJP70547.1 - 3.4 8.1 32.0 3.2 8.2 3.0 3.2 2 1 0 2 2 2 0 Fez1 BLOC1_2 PF10046.9 EJP70547.1 - 3.5 8.0 18.7 0.19 12.0 2.4 3.7 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF241 PF03087.14 EJP70547.1 - 3.6 7.4 17.1 0.47 10.3 4.2 3.4 2 1 0 3 3 3 0 Arabidopsis protein of unknown function Fib_alpha PF08702.10 EJP70547.1 - 5.5 7.2 19.8 1.7 8.9 4.1 3.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family XLF PF09302.11 EJP70547.1 - 9.2 6.4 11.7 43 4.2 0.3 3.6 2 1 1 4 4 4 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TMPIT PF07851.13 EJP70547.1 - 9.3 5.4 11.1 7.6 5.7 0.1 3.3 2 1 2 4 4 4 0 TMPIT-like protein tRNA-synt_1 PF00133.22 EJP70548.1 - 1.8e-221 736.6 1.3 4.2e-220 732.1 1.3 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EJP70548.1 - 2.6e-35 121.6 2.0 2.6e-35 121.6 2.0 2.8 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EJP70548.1 - 6.8e-16 58.0 0.1 3.6e-06 26.0 0.0 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EJP70548.1 - 9.3e-13 48.1 0.1 1.5e-09 37.6 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 EJP70548.1 - 1e-05 25.7 4.1 1e-05 25.7 4.1 3.0 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 EJP70548.1 - 0.089 12.1 0.0 0.63 9.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DEAD PF00270.29 EJP70550.1 - 2.5e-16 60.0 0.0 5.3e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJP70550.1 - 6.8e-06 26.4 0.0 2.4e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP70550.1 - 0.00025 21.1 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 EJP70550.1 - 0.0057 17.2 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain zf-HC5HC2H_2 PF13832.6 EJP70551.1 - 8.4e-21 74.2 1.4 8.4e-21 74.2 1.4 4.7 4 1 1 5 5 5 1 PHD-zinc-finger like domain BAH PF01426.18 EJP70551.1 - 1.8e-16 60.1 0.7 3.6e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 BAH domain zf-HC5HC2H PF13771.6 EJP70551.1 - 1.8e-16 60.2 2.7 1.8e-16 60.2 2.7 4.8 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 EJP70551.1 - 5.7e-12 45.4 52.5 9.4e-07 28.6 7.5 5.9 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 EJP70551.1 - 8.4e-08 31.6 5.1 8.4e-08 31.6 5.1 5.1 5 0 0 5 5 5 2 PHD-finger C1_1 PF00130.22 EJP70551.1 - 0.0018 18.1 2.0 0.0018 18.1 2.0 5.6 5 1 1 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EJP70551.1 - 0.021 14.7 30.3 0.019 14.9 1.8 4.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 SAM_PNT PF02198.16 EJP70552.1 - 0.056 13.4 0.0 0.086 12.8 0.0 1.3 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain MFS_1 PF07690.16 EJP70553.1 - 1.1e-39 136.4 42.3 1.1e-39 136.4 42.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EJP70553.1 - 9e-05 21.9 7.2 9e-05 21.9 7.2 3.1 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB PTR2 PF00854.21 EJP70553.1 - 0.0033 16.3 5.5 0.0087 14.9 5.2 1.9 1 1 1 2 2 2 1 POT family Nop14 PF04147.12 EJP70554.1 - 6.9e-295 980.8 23.3 8.5e-295 980.5 23.3 1.1 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 EJP70554.1 - 0.013 14.7 0.7 0.024 13.9 0.0 1.7 2 0 0 2 2 2 0 Noc2p family DUF3546 PF12066.8 EJP70555.1 - 1.6e-23 83.0 0.3 1.6e-23 83.0 0.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 EJP70555.1 - 4.2e-14 53.4 1.2 1.1e-13 52.0 1.2 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 EJP70555.1 - 2.8e-11 43.0 0.1 6.4e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Tsc35 PF15079.6 EJP70556.1 - 0.0012 18.5 0.4 0.002 17.8 0.4 1.3 1 0 0 1 1 1 1 Testis-specific protein 35 AAA PF00004.29 EJP70557.1 - 3e-40 137.7 0.0 5.4e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJP70557.1 - 2.2e-07 30.6 0.0 5.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EJP70557.1 - 9.7e-05 22.4 0.1 0.00063 19.8 0.0 2.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EJP70557.1 - 0.00015 22.0 0.0 0.0055 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EJP70557.1 - 0.00032 20.9 0.0 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EJP70557.1 - 0.00068 20.1 0.1 0.014 15.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EJP70557.1 - 0.0016 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EJP70557.1 - 0.0092 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EJP70557.1 - 0.024 14.9 0.0 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJP70557.1 - 0.033 13.7 0.0 0.096 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EJP70557.1 - 0.035 13.8 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJP70557.1 - 0.04 14.3 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EJP70557.1 - 0.045 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EJP70557.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EJP70557.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EJP70557.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 EJP70558.1 - 1.9e-148 495.2 16.3 2.1e-148 495.0 16.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.6 EJP70558.1 - 0.029 14.3 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) Orbi_VP2 PF00898.17 EJP70559.1 - 0.0013 16.6 3.2 0.0014 16.5 3.2 1.0 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP2 DUF3834 PF12916.7 EJP70559.1 - 0.0029 16.9 1.7 0.0035 16.6 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3834) GrpE PF01025.19 EJP70559.1 - 0.0032 17.1 8.2 0.0038 16.9 8.2 1.1 1 0 0 1 1 1 1 GrpE Methyltransf_29 PF03141.16 EJP70559.1 - 0.04 12.5 0.9 0.04 12.5 0.9 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase VWA_CoxE PF05762.14 EJP70559.1 - 0.041 13.3 1.7 0.043 13.2 1.7 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Vta1 PF04652.16 EJP70559.1 - 0.061 13.3 2.8 0.082 12.9 2.8 1.3 1 0 0 1 1 1 0 Vta1 like Raco_middle PF17651.1 EJP70559.1 - 0.13 12.0 2.1 0.19 11.4 1.8 1.5 1 1 0 1 1 1 0 RACo middle region DUF148 PF02520.17 EJP70559.1 - 0.27 11.4 6.8 0.69 10.0 6.7 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF148 MSC PF09402.10 EJP70559.1 - 0.52 9.7 4.6 0.63 9.4 4.6 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain ZYG-11_interact PF05884.12 EJP70559.1 - 0.72 9.2 3.2 0.84 9.0 3.2 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 COX17 PF05051.13 EJP70560.1 - 3.2e-21 75.4 6.7 3.9e-21 75.1 6.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF3712 PF12505.8 EJP70561.1 - 6.7e-22 78.1 0.0 1.2e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF2891 PF11199.8 EJP70561.1 - 0.044 12.7 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Cauli_VI PF01693.16 EJP70562.1 - 3.3e-20 72.1 2.0 9.4e-18 64.2 1.1 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin DUF1929 PF09118.11 EJP70563.1 - 1.1e-21 76.9 0.0 2.4e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 EJP70563.1 - 6.1e-21 74.9 1.7 1.7e-20 73.4 1.7 1.8 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.6 EJP70563.1 - 7e-13 48.4 2.5 0.00099 19.3 0.1 4.5 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EJP70563.1 - 8.8e-11 41.2 0.1 1.6e-06 27.6 0.1 4.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 EJP70563.1 - 3.7e-06 26.7 3.2 0.062 13.3 0.3 5.4 6 1 0 6 6 6 2 Kelch motif Glyoxal_oxid_N PF07250.11 EJP70563.1 - 4.7e-06 26.0 0.0 0.009 15.2 0.0 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_4 PF13418.6 EJP70563.1 - 0.00011 22.2 4.9 1.4 9.0 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain DUF5000 PF16391.5 EJP70563.1 - 0.052 13.7 0.1 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function FAD_binding_3 PF01494.19 EJP70565.1 - 3.9e-09 36.2 0.4 1.2e-06 28.0 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EJP70565.1 - 0.001 19.3 0.4 0.0021 18.2 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP70565.1 - 0.0013 18.0 1.1 0.0072 15.6 0.9 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJP70565.1 - 0.039 13.2 0.4 0.06 12.6 0.4 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EJP70565.1 - 0.052 13.5 0.4 0.23 11.4 0.4 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 EJP70565.1 - 0.066 12.8 1.2 0.96 9.0 0.9 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF3328 PF11807.8 EJP70566.1 - 5.5e-45 153.8 0.1 6.2e-45 153.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EJP70567.1 - 0.019 14.8 1.2 0.028 14.2 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) CDH-cyt PF16010.5 EJP70568.1 - 2.5e-16 59.9 0.0 3.9e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EJP70568.1 - 0.028 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 DOMON domain DUF3328 PF11807.8 EJP70569.1 - 2.1e-09 37.5 0.0 2.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 2OG-FeII_Oxy_3 PF13640.6 EJP70572.1 - 3.2e-10 40.7 0.0 7.1e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_S9 PF00326.21 EJP70573.1 - 1.2e-42 145.8 1.8 2.4e-42 144.8 1.8 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 EJP70573.1 - 1.8e-33 115.8 0.2 2.3e-30 105.6 0.0 2.2 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 EJP70573.1 - 6.6e-06 25.9 1.4 2e-05 24.3 0.4 2.2 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EJP70573.1 - 2.1e-05 24.2 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 EJP70573.1 - 0.00058 19.6 1.7 0.0011 18.7 1.1 1.9 2 1 0 2 2 2 1 Putative esterase Esterase_phd PF10503.9 EJP70573.1 - 0.011 15.3 0.3 0.019 14.4 0.3 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_4 PF08386.10 EJP70573.1 - 0.049 13.7 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 EJP70573.1 - 0.055 13.1 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EJP70573.1 - 0.13 11.5 0.5 7.2 5.8 0.0 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Cyclin_N PF00134.23 EJP70574.1 - 1.1e-37 128.5 0.2 4e-37 126.8 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EJP70574.1 - 5.8e-13 49.0 0.3 2.4e-12 47.0 0.3 2.1 1 1 0 1 1 1 1 Cyclin, C-terminal domain Collagen PF01391.18 EJP70575.1 - 5.4e-06 26.1 21.0 5.4e-06 26.1 21.0 1.7 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Cation_efflux PF01545.21 EJP70577.1 - 5.6e-53 179.6 0.8 9.9e-53 178.8 0.8 1.4 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EJP70577.1 - 0.048 13.8 0.2 0.097 12.8 0.2 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter BCLP PF12304.8 EJP70577.1 - 0.13 11.8 0.7 0.25 10.9 0.7 1.4 1 0 0 1 1 1 0 Beta-casein like protein Ribosomal_S5 PF00333.20 EJP70578.1 - 1.5e-27 95.4 1.2 4e-27 94.0 1.2 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EJP70578.1 - 5.6e-22 77.0 0.0 9e-22 76.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Rhodanese PF00581.20 EJP70579.1 - 1.9e-16 60.5 0.0 4.5e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain zf-ANAPC11 PF12861.7 EJP70580.1 - 2.7e-45 152.3 10.9 3.3e-45 152.1 10.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EJP70580.1 - 2.8e-21 75.5 12.2 4.9e-21 74.8 12.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EJP70580.1 - 4.7e-08 33.2 17.4 1.5e-06 28.4 17.4 2.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EJP70580.1 - 5.4e-05 23.1 10.9 0.0001 22.3 3.9 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EJP70580.1 - 9.5e-05 22.2 5.0 9.5e-05 22.2 5.0 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EJP70580.1 - 0.00015 21.8 1.8 0.00015 21.8 1.8 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EJP70580.1 - 0.00051 19.9 13.0 0.0011 18.7 8.5 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP70580.1 - 0.00073 19.4 14.6 0.0029 17.5 14.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EJP70580.1 - 0.00099 18.9 3.1 0.00099 18.9 3.1 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EJP70580.1 - 0.0024 18.0 16.2 0.032 14.4 16.2 2.8 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EJP70580.1 - 0.0095 15.5 11.8 0.12 12.0 11.8 2.3 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 EJP70580.1 - 0.011 15.6 4.9 0.018 14.8 4.9 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 EJP70580.1 - 0.028 14.4 15.8 0.53 10.3 16.3 2.4 1 1 1 2 2 2 0 zinc-RING finger domain Rad50_zn_hook PF04423.14 EJP70580.1 - 0.057 13.3 0.0 0.057 13.3 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2256 PF10013.9 EJP70580.1 - 0.27 11.4 0.3 0.27 11.4 0.3 3.2 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) RINGv PF12906.7 EJP70580.1 - 0.9 9.7 13.1 2.2 8.5 12.2 2.2 1 1 1 2 2 2 0 RING-variant domain zf-RING_11 PF17123.5 EJP70580.1 - 1.5 8.7 14.4 1.5 8.6 10.3 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-RING-like PF08746.11 EJP70580.1 - 2.3 8.6 13.8 3.6 8.0 11.5 2.2 1 1 1 2 2 2 0 RING-like domain DZR PF12773.7 EJP70580.1 - 3.1 7.9 12.5 2.2 8.3 5.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF393 PF04134.12 EJP70580.1 - 6.1 8.2 6.5 29 6.0 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function, DUF393 Pro_dh PF01619.18 EJP70582.1 - 1.4e-62 211.9 0.5 1.7e-62 211.6 0.5 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Flavin_Reduct PF01613.18 EJP70583.1 - 5e-16 59.1 0.1 2e-15 57.2 0.0 1.8 2 0 0 2 2 2 1 Flavin reductase like domain Fungal_trans PF04082.18 EJP70584.1 - 4.9e-11 42.2 0.1 8.9e-11 41.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 EJP70585.1 - 2.7e-57 194.1 0.0 3.7e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70585.1 - 1.3e-27 96.7 0.0 2.3e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP70585.1 - 8.7e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJP70585.1 - 0.0064 16.4 0.4 0.3 11.0 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EJP70585.1 - 0.0071 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 EJP70586.1 - 4.1e-47 159.4 0.0 5.1e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EJP70586.1 - 1.5e-05 24.7 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EJP70586.1 - 0.0056 16.5 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 EJP70586.1 - 0.0066 16.7 0.0 0.0096 16.2 0.0 1.5 1 1 0 1 1 1 1 RWD domain Ribosomal_L31e PF01198.19 EJP70587.1 - 8.4e-39 131.7 1.4 1.1e-38 131.3 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e RGS PF00615.19 EJP70588.1 - 6.5e-12 45.8 0.0 3.3e-10 40.3 0.0 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain PCI PF01399.27 EJP70589.1 - 2.9e-05 24.5 0.0 4.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 EJP70589.1 - 0.0036 17.2 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain E1-E2_ATPase PF00122.20 EJP70590.1 - 4.1e-49 166.5 0.4 1.2e-48 165.1 0.4 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 EJP70590.1 - 3.6e-42 142.6 4.7 1.3e-11 44.8 0.0 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EJP70590.1 - 3.5e-37 128.8 7.1 1e-36 127.2 7.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EJP70590.1 - 2e-05 24.5 1.5 0.00022 21.0 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP70590.1 - 0.02 15.3 0.6 0.27 11.6 0.1 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 EJP70590.1 - 0.052 13.6 2.3 4.5 7.3 0.0 4.4 5 0 0 5 5 5 0 B12 binding domain CM_2 PF01817.21 EJP70590.1 - 0.057 13.8 0.0 33 4.9 0.0 3.4 3 0 0 3 3 3 0 Chorismate mutase type II DSBA PF01323.20 EJP70590.1 - 0.075 12.8 1.1 12 5.6 0.2 3.3 3 0 0 3 3 3 0 DSBA-like thioredoxin domain DUF1656 PF07869.12 EJP70590.1 - 0.31 11.1 4.6 0.87 9.6 1.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) p450 PF00067.22 EJP70591.1 - 2.2e-73 247.6 0.0 2.6e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Corona_NS4 PF03905.13 EJP70592.1 - 0.011 15.8 0.1 0.024 14.7 0.1 1.6 1 0 0 1 1 1 0 Coronavirus non-structural protein NS4 BLOC1S3 PF15753.5 EJP70592.1 - 0.066 13.3 2.6 0.13 12.4 2.6 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Nop14 PF04147.12 EJP70592.1 - 0.11 10.6 1.4 0.17 10.1 1.4 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 EJP70592.1 - 0.38 10.4 7.2 0.15 11.8 3.4 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EJP70592.1 - 5.6 6.2 4.9 8.5 5.6 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EJP70592.1 - 7 4.6 9.8 10 4.1 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Fructosamin_kin PF03881.14 EJP70594.1 - 1.1e-12 47.7 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase TruB-C_2 PF09157.11 EJP70594.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal CHORD PF04968.12 EJP70595.1 - 1.9 9.3 7.6 0.93 10.3 0.2 2.8 2 1 0 2 2 2 0 CHORD CHORD PF04968.12 EJP70596.1 - 0.049 14.3 0.7 0.049 14.3 0.7 2.8 2 1 0 2 2 2 0 CHORD RRM_1 PF00076.22 EJP70597.1 - 3.7e-42 142.0 0.2 3.9e-20 71.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJP70597.1 - 4.8e-05 23.4 0.0 0.44 10.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 EJP70597.1 - 0.0014 18.5 0.0 0.009 15.8 0.0 2.3 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 EJP70597.1 - 0.0058 16.6 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 EJP70597.1 - 0.0064 16.1 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated NDUFB10 PF10249.9 EJP70598.1 - 0.0022 18.5 0.0 0.0028 18.2 0.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Ribosomal_L37 PF08561.10 EJP70599.1 - 4.9e-42 143.2 3.6 6e-42 142.9 3.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 WH2 PF02205.20 EJP70600.1 - 8.3e-09 35.0 0.1 8.3e-09 35.0 0.1 2.4 3 0 0 3 3 3 1 WH2 motif APH PF01636.23 EJP70602.1 - 4.7e-12 46.3 0.1 6.1e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EJP70602.1 - 8.6e-05 22.0 0.1 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EJP70602.1 - 0.004 16.8 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EJP70602.1 - 0.18 10.6 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Abhydrolase_1 PF00561.20 EJP70604.1 - 8.7e-19 68.2 0.1 1e-17 64.6 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP70604.1 - 8.4e-13 48.1 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJP70604.1 - 5e-12 46.9 0.0 6.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EJP70604.1 - 2.8e-06 26.3 0.0 6.9e-06 25.0 0.0 1.6 2 0 0 2 2 2 1 Ndr family Chlorophyllase2 PF12740.7 EJP70604.1 - 0.00012 21.1 0.0 0.00029 19.8 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF1057 PF06342.12 EJP70604.1 - 0.0024 17.0 0.0 0.0058 15.7 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase PF07224.11 EJP70604.1 - 0.0038 16.3 0.0 0.0084 15.1 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase UPF0227 PF05728.12 EJP70604.1 - 0.0098 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Esterase PF00756.20 EJP70604.1 - 0.028 14.0 0.1 0.062 12.9 0.0 1.5 1 1 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 EJP70604.1 - 0.038 13.7 0.3 0.075 12.7 0.3 1.5 1 1 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.13 EJP70604.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 1 1 2 2 2 0 Serine hydrolase Lipase_3 PF01764.25 EJP70604.1 - 0.051 13.4 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 EJP70604.1 - 0.058 12.7 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 EJP70604.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 EJP70604.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_A4 PF01828.17 EJP70605.1 - 4.9e-55 186.2 5.1 5.8e-55 186.0 5.1 1.0 1 0 0 1 1 1 1 Peptidase A4 family Fungal_trans PF04082.18 EJP70607.1 - 9.8e-13 47.7 0.1 2.3e-12 46.5 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP70607.1 - 2.8e-08 33.7 10.3 4.9e-08 33.0 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DJ-1_PfpI PF01965.24 EJP70608.1 - 8.5e-07 28.9 0.0 5e-05 23.2 0.0 2.8 2 1 0 2 2 2 1 DJ-1/PfpI family JmjC PF02373.22 EJP70609.1 - 7.8e-20 71.4 0.0 1e-18 67.8 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase GIT_SHD PF08518.11 EJP70610.1 - 4.7e-20 70.9 9.6 4.3e-13 48.6 1.5 3.0 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT DUF5136 PF17199.4 EJP70610.1 - 0.057 13.1 0.1 0.057 13.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5136) Lebercilin PF15619.6 EJP70610.1 - 0.23 11.1 30.9 0.91 9.2 11.7 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PCEMA1 PF07418.11 EJP70610.1 - 0.65 9.5 10.7 1.1 8.7 10.7 1.4 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 FUSC PF04632.12 EJP70610.1 - 1.3 7.5 20.5 0.26 9.8 15.0 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family FAM76 PF16046.5 EJP70610.1 - 1.9 7.8 14.9 0.06 12.7 5.0 2.2 2 0 0 2 2 2 0 FAM76 protein Herpes_UL25 PF01499.16 EJP70610.1 - 2.1 6.8 10.4 2.5 6.5 9.4 1.6 1 1 0 1 1 1 0 Herpesvirus UL25 family CLZ PF16526.5 EJP70610.1 - 6.2 7.3 25.0 0.35 11.3 1.6 3.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PSII_Pbs27 PF13326.6 EJP70610.1 - 8.3 6.7 8.8 2.8 8.3 1.3 2.4 1 1 0 2 2 2 0 Photosystem II Pbs27 Ssu72 PF04722.13 EJP70611.1 - 9e-87 289.6 0.0 1e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.28 EJP70612.1 - 3.8e-09 36.0 0.0 6.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP70612.1 - 8.5e-08 31.9 0.1 2e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJP70612.1 - 6.5e-06 25.7 0.0 9.7e-05 22.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Lactamase_B PF00753.27 EJP70613.1 - 7.1e-18 65.3 0.4 1e-17 64.8 0.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EJP70613.1 - 6.1e-07 29.2 0.4 8.5e-07 28.7 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PH PF00169.29 EJP70613.1 - 0.061 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 PH domain Tautomerase_3 PF14832.6 EJP70614.1 - 2.8e-43 147.4 0.0 3.2e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme CRF PF00473.17 EJP70614.1 - 0.025 14.6 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 Corticotropin-releasing factor family NAD_binding_1 PF00175.21 EJP70615.1 - 2.1e-31 108.8 0.0 3.4e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EJP70615.1 - 5.6e-25 87.6 0.0 1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EJP70615.1 - 8.3e-08 32.5 0.0 0.00099 19.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Cutinase PF01083.22 EJP70616.1 - 3.2e-31 108.7 1.3 4.6e-31 108.1 1.3 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EJP70616.1 - 0.0026 17.4 0.1 0.0042 16.7 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 EJP70616.1 - 0.029 14.2 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3089 PF11288.8 EJP70616.1 - 0.045 13.3 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) MARVEL PF01284.23 EJP70618.1 - 0.15 12.1 21.1 2.3 8.2 5.3 2.8 2 1 1 3 3 3 0 Membrane-associating domain TFR_dimer PF04253.15 EJP70619.1 - 7.8e-25 87.3 0.0 1.6e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EJP70619.1 - 6.1e-19 68.5 0.0 1.8e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EJP70619.1 - 2.1e-10 40.4 0.8 6.3e-10 39.0 0.1 2.2 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 EJP70619.1 - 0.087 12.3 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.16 EJP70620.1 - 2e-33 115.8 26.3 8.8e-28 97.2 19.1 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP70620.1 - 1.5e-10 40.5 1.4 1.5e-10 40.5 1.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP70620.1 - 0.0011 17.5 0.2 0.0023 16.4 0.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3246 PF11596.8 EJP70620.1 - 0.11 11.9 4.2 0.17 11.3 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 EJP70620.1 - 0.76 9.5 4.4 1.1 8.9 4.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SprT-like PF10263.9 EJP70621.1 - 2.3e-13 50.0 0.0 4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 SprT-like family F-box-like PF12937.7 EJP70622.1 - 4.2e-11 42.6 4.0 4.7e-11 42.4 2.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EJP70622.1 - 5.8e-10 38.8 0.5 1.3e-09 37.7 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EJP70622.1 - 0.0028 17.5 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 F-box Asp PF00026.23 EJP70625.1 - 3.7e-20 72.6 0.0 7.1e-20 71.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJP70625.1 - 0.00019 21.7 0.0 0.0038 17.5 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Epimerase PF01370.21 EJP70626.1 - 2.2e-11 43.7 0.0 6.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJP70626.1 - 8.8e-10 38.8 0.0 2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EJP70626.1 - 1.6e-05 24.6 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EJP70626.1 - 0.00015 21.3 0.1 0.0044 16.5 0.0 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EJP70626.1 - 0.0022 17.1 0.0 0.0061 15.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EJP70626.1 - 0.0069 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EJP70626.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 EJP70626.1 - 0.02 15.3 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EJP70626.1 - 0.11 11.7 0.0 0.78 8.8 0.0 2.3 2 1 0 2 2 2 0 Male sterility protein HSP70 PF00012.20 EJP70627.1 - 4.4e-225 748.4 6.1 4.9e-225 748.3 6.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJP70627.1 - 1e-15 57.4 0.4 7.9e-15 54.5 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EJP70627.1 - 0.00018 21.3 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EJP70627.1 - 0.005 16.4 0.1 1 8.8 0.0 2.7 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 EJP70627.1 - 0.16 12.4 4.8 6.1 7.3 0.1 3.4 3 2 0 3 3 3 0 Cell division protein FtsA IMUP PF15761.5 EJP70629.1 - 6.8 7.4 7.8 21 5.8 7.8 1.9 1 1 0 1 1 1 0 Immortalisation up-regulated protein RNA_pol_Rpb1_1 PF04997.12 EJP70630.1 - 7.1e-108 360.6 0.0 1.1e-107 360.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EJP70630.1 - 1.2e-99 333.1 0.0 2e-99 332.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EJP70630.1 - 1.4e-76 256.3 0.0 2.9e-76 255.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EJP70630.1 - 6.4e-58 195.8 0.2 1e-57 195.0 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EJP70630.1 - 1.2e-46 158.5 0.0 2.3e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EJP70630.1 - 2.1e-46 157.2 11.2 1.1e-45 155.0 10.6 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EJP70630.1 - 5.5e-36 122.8 0.2 1.2e-35 121.7 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EJP70630.1 - 0.0029 17.9 8.7 0.0029 17.9 8.7 14.1 8 4 4 14 14 14 6 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 EJP70631.1 - 4.1e-12 46.4 6.6 0.0037 18.1 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP70631.1 - 2.4e-10 40.6 0.3 0.0037 17.5 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJP70631.1 - 1.1e-05 25.4 0.1 0.021 14.7 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Thg1C PF14413.6 EJP70632.1 - 1.7e-50 170.2 0.6 2.4e-50 169.8 0.6 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 EJP70632.1 - 4.1e-50 169.0 0.0 5.9e-50 168.5 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase GAGA_bind PF06217.12 EJP70633.1 - 0.13 12.5 8.5 0.17 12.2 8.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SRP-alpha_N PF04086.13 EJP70633.1 - 0.28 11.1 20.4 0.41 10.5 20.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 EJP70633.1 - 1 8.1 12.8 1.2 7.8 12.8 1.1 1 0 0 1 1 1 0 Presenilin DUF2992 PF11208.8 EJP70633.1 - 1 9.6 26.3 1.6 8.9 26.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) SAPS PF04499.15 EJP70633.1 - 1.7 7.4 9.0 1.8 7.2 9.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ALMT PF11744.8 EJP70633.1 - 3.2 6.5 7.6 3.4 6.4 7.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter U79_P34 PF03064.16 EJP70633.1 - 4.1 6.7 17.6 5.4 6.3 17.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AAA_11 PF13086.6 EJP70633.1 - 5.2 6.8 13.2 6.3 6.5 13.2 1.1 1 0 0 1 1 1 0 AAA domain Rtf2 PF04641.12 EJP70633.1 - 7.2 5.9 19.0 11 5.3 19.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.7 EJP70633.1 - 8.8 4.3 9.4 9.7 4.2 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF726 PF05277.12 EJP70634.1 - 1.1e-114 382.9 0.1 1.7e-114 382.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PE-PPE PF08237.11 EJP70634.1 - 0.085 12.4 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 PE-PPE domain Thioesterase PF00975.20 EJP70634.1 - 0.098 12.8 0.0 0.098 12.8 0.0 1.9 3 0 0 3 3 3 0 Thioesterase domain Cutinase PF01083.22 EJP70634.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.7 EJP70634.1 - 0.39 11.3 8.3 0.062 13.9 1.7 2.3 1 1 0 2 2 2 0 Alpha/beta hydrolase family DUF1708 PF08101.11 EJP70635.1 - 2.5e-167 557.4 0.0 3.7e-167 556.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.19 EJP70636.1 - 6.3e-23 81.5 0.0 1.1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sel1 PF08238.12 EJP70637.1 - 7.1e-39 131.4 43.4 4.4e-08 33.5 0.1 11.8 11 2 0 11 11 11 9 Sel1 repeat Pax2_C PF12403.8 EJP70637.1 - 0.058 13.5 0.3 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Paired-box protein 2 C terminal TPR_17 PF13431.6 EJP70637.1 - 0.15 12.5 9.8 48 4.7 0.4 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat RCR PF12273.8 EJP70638.1 - 1.7e-07 31.9 14.6 6.1e-07 30.1 14.6 2.0 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red tRNA-synt_2c PF01411.19 EJP70640.1 - 3.1e-214 712.6 0.0 5e-214 711.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EJP70640.1 - 6.1e-17 61.5 0.1 1.4e-16 60.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EJP70640.1 - 1.1e-10 42.0 2.3 1.1e-10 42.0 2.3 1.9 2 0 0 2 2 2 1 DHHA1 domain Mitoc_L55 PF09776.9 EJP70640.1 - 0.076 12.8 0.5 68 3.2 0.0 3.6 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L55 Methyltransf_28 PF02636.17 EJP70641.1 - 1.4e-39 136.4 0.0 2.2e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EJP70641.1 - 0.0045 16.9 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PALP PF00291.25 EJP70642.1 - 1.3e-62 211.9 3.0 1.7e-62 211.5 3.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TFIIS_M PF07500.14 EJP70643.1 - 3.3e-26 92.0 0.5 3.3e-26 92.0 0.5 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EJP70643.1 - 6.1e-18 64.4 7.5 9.8e-18 63.7 7.5 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EJP70643.1 - 1.4e-11 44.2 0.7 5e-11 42.4 0.2 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain YkyA PF10368.9 EJP70643.1 - 3.8 7.1 9.4 0.37 10.4 1.9 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein XPG_N PF00752.17 EJP70644.1 - 1.2e-33 115.6 0.0 2.8e-33 114.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EJP70644.1 - 8.1e-27 93.4 0.0 2.5e-26 91.8 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 EJP70644.1 - 7.5e-05 22.4 1.2 0.00076 19.2 1.2 3.0 1 0 0 1 1 1 1 Ubiquitin interaction motif 5_3_exonuc PF01367.20 EJP70644.1 - 0.026 15.1 0.0 0.13 12.9 0.0 2.3 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold LSM PF01423.22 EJP70645.1 - 8.3e-11 41.4 0.0 9.7e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EJP70645.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain Pil1 PF13805.6 EJP70646.1 - 1.4e-124 414.9 0.3 1.7e-124 414.6 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 EZH2_N PF18601.1 EJP70647.1 - 3.5e-37 126.6 4.1 9.6e-37 125.2 3.8 2.0 2 0 0 2 2 2 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 EJP70647.1 - 1.1e-25 89.0 0.8 2e-25 88.1 0.8 1.5 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 EJP70647.1 - 5.3e-14 52.9 0.0 5.3e-14 52.9 0.0 3.7 3 3 0 3 3 3 1 SET domain preSET_CXC PF18264.1 EJP70647.1 - 7.9e-06 26.2 14.3 7.9e-06 26.2 14.3 3.6 2 1 1 3 3 3 1 CXC domain HTH_32 PF13565.6 EJP70647.1 - 3.2 8.4 7.1 0.22 12.2 0.7 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Bap31 PF05529.12 EJP70648.1 - 3.4e-49 166.2 8.6 5.4e-49 165.5 8.6 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EJP70648.1 - 3.4e-12 46.2 14.8 5.6e-12 45.5 14.8 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain ubiquitin PF00240.23 EJP70648.1 - 0.079 12.7 0.2 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin family HetR_C PF18460.1 EJP70648.1 - 0.082 12.8 0.2 0.89 9.5 0.1 2.1 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain DivIC PF04977.15 EJP70648.1 - 0.1 12.4 10.8 0.11 12.2 5.4 3.0 2 1 1 3 3 3 0 Septum formation initiator RhoGEF67_u2 PF16614.5 EJP70648.1 - 0.14 12.2 0.5 0.23 11.5 0.5 1.3 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 PhoLip_ATPase_C PF16212.5 EJP70648.1 - 1.7 8.3 8.7 0.81 9.4 6.1 1.6 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal Tad PF13400.6 EJP70648.1 - 2.7 8.4 3.9 2.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like SlyX PF04102.12 EJP70648.1 - 3.7 8.2 7.5 0.44 11.2 2.4 2.0 3 0 0 3 3 3 0 SlyX HHH PF00633.23 EJP70649.1 - 0.04 13.8 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Herpes_pp85 PF04637.12 EJP70649.1 - 0.64 8.4 4.2 1 7.7 4.2 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF2681 PF10883.8 EJP70649.1 - 1.3 9.4 8.6 4.1 7.9 5.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF4692 PF15763.5 EJP70649.1 - 3.7 8.0 7.9 0.37 11.3 0.5 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Fungal_trans_2 PF11951.8 EJP70650.1 - 5.2e-05 22.2 0.7 8.4e-05 21.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_1 PF00190.22 EJP70651.1 - 1.1e-10 41.3 0.3 3.8e-10 39.6 0.3 1.8 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EJP70651.1 - 0.0089 15.7 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 1 Cupin domain MFS_1 PF07690.16 EJP70652.1 - 1.5e-34 119.5 22.4 4.9e-33 114.5 23.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EJP70652.1 - 0.00059 19.2 4.2 0.00059 19.2 4.2 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 EJP70653.1 - 6.2e-11 41.8 26.2 1.8e-08 33.7 24.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EJP70653.1 - 4.3e-05 23.3 3.3 4.3e-05 23.3 3.3 2.2 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 LAB_N PF07578.11 EJP70653.1 - 0.037 14.1 5.8 0.083 13.0 1.7 2.8 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain F-box-like PF12937.7 EJP70654.1 - 0.026 14.4 2.9 0.49 10.3 0.1 2.4 2 0 0 2 2 2 0 F-box-like zf-met2 PF12907.7 EJP70655.1 - 5e-17 61.8 1.8 5e-17 61.8 1.8 1.4 2 0 0 2 2 2 1 Zinc-binding DIOX_N PF14226.6 EJP70656.1 - 4e-35 121.1 0.0 1.3e-33 116.2 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EJP70656.1 - 8e-12 45.5 0.0 1.8e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 EJP70657.1 - 3.3e-09 37.2 8.5 0.0076 17.1 0.5 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJP70657.1 - 0.0019 18.4 0.5 11 6.4 0.1 5.3 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_N PF01194.17 EJP70658.1 - 2.1e-29 101.6 1.0 2.6e-29 101.3 1.0 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EJP70658.1 - 0.021 15.0 0.2 0.034 14.4 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) MmgE_PrpD PF03972.14 EJP70658.1 - 0.2 10.1 0.0 0.21 10.1 0.0 1.0 1 0 0 1 1 1 0 MmgE/PrpD family CAF1A PF12253.8 EJP70661.1 - 0.28 11.4 3.3 0.44 10.7 1.3 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A NACHT_N PF17100.5 EJP70662.1 - 8.2e-52 176.2 1.6 2.3e-51 174.8 1.6 1.8 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 EJP70662.1 - 1.3e-07 31.7 0.1 2.6e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 EJP70662.1 - 7.6e-05 22.2 0.0 0.00022 20.8 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.6 EJP70662.1 - 9.4e-05 22.9 0.1 0.0003 21.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP70662.1 - 0.0059 16.9 0.0 0.019 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJP70662.1 - 0.024 15.0 0.4 0.55 10.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain CSTF2_hinge PF14327.6 EJP70662.1 - 0.055 13.9 0.2 0.14 12.6 0.2 1.7 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 PD40 PF07676.12 EJP70662.1 - 0.09 12.7 0.0 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PIG-P PF08510.12 EJP70663.1 - 4.9e-42 142.7 0.3 7.9e-42 142.0 0.3 1.3 1 0 0 1 1 1 1 PIG-P CPSF100_C PF13299.6 EJP70663.1 - 0.24 11.5 4.8 0.51 10.5 4.8 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 EJP70663.1 - 0.35 10.0 4.6 1.4 8.0 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DPM2 PF07297.12 EJP70663.1 - 3.5 8.0 7.5 6 7.3 7.5 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) BUD22 PF09073.10 EJP70663.1 - 4.6 6.5 18.7 0.98 8.7 0.7 2.1 2 0 0 2 2 2 0 BUD22 Vps8 PF12816.7 EJP70664.1 - 1.4e-72 243.4 0.9 5.7e-71 238.1 0.0 3.1 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_5 PF14634.6 EJP70664.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF4745 PF15923.5 EJP70664.1 - 0.012 15.6 0.2 0.044 13.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) zf-RING_UBOX PF13445.6 EJP70664.1 - 0.012 15.6 0.1 0.031 14.3 0.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 EJP70664.1 - 0.031 14.1 0.2 0.093 12.6 0.2 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 EJP70664.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 EJP70664.1 - 0.076 12.8 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3H2C3 PF17122.5 EJP70664.1 - 0.14 12.2 0.2 0.35 11.0 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 EJP70664.1 - 0.17 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain MgtE_N PF03448.17 EJP70664.1 - 0.82 10.3 3.1 1.7 9.3 0.6 2.8 3 0 0 3 3 3 0 MgtE intracellular N domain DUF3752 PF12572.8 EJP70665.1 - 4.1e-45 154.0 4.3 4.1e-45 154.0 4.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.6 EJP70666.1 - 2.2e-11 43.9 6.4 3.5e-11 43.2 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJP70666.1 - 5.3e-08 32.6 6.0 8.6e-08 31.9 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJP70666.1 - 5.7e-08 32.4 1.2 9.8e-08 31.6 1.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EJP70666.1 - 8.4e-08 32.0 4.2 1.4e-07 31.2 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EJP70666.1 - 1.5e-06 28.3 8.0 4.9e-06 26.7 8.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EJP70666.1 - 1e-05 25.4 3.4 1.6e-05 24.7 3.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EJP70666.1 - 0.0033 17.4 1.0 0.0033 17.4 1.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EJP70666.1 - 0.0043 17.1 5.1 0.014 15.4 5.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EJP70666.1 - 0.0054 16.6 2.8 0.009 15.9 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EJP70666.1 - 0.015 15.0 6.6 0.028 14.2 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EJP70666.1 - 0.18 11.7 4.7 0.39 10.6 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 EJP70666.1 - 0.2 11.6 5.6 0.37 10.7 5.6 1.5 1 0 0 1 1 1 0 PHD-finger OAD_gamma PF04277.13 EJP70666.1 - 0.39 11.4 8.0 0.65 10.6 0.0 3.8 3 1 0 3 3 2 0 Oxaloacetate decarboxylase, gamma chain FANCL_C PF11793.8 EJP70666.1 - 0.4 10.9 3.1 1.2 9.4 3.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EJP70666.1 - 0.54 9.9 4.4 1 9.0 4.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EJP70666.1 - 0.91 9.7 4.7 2.1 8.6 4.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Glyco_hydro_18 PF00704.28 EJP70667.1 - 5.9e-50 170.8 4.1 1.1e-49 169.9 4.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 EJP70667.1 - 7.7e-24 83.9 1.4 2e-23 82.6 0.1 2.6 3 0 0 3 3 3 1 Pathogen effector; putative necrosis-inducing factor Chitin_bind_1 PF00187.19 EJP70667.1 - 2.1e-05 24.9 9.2 2.1e-05 24.9 9.2 4.2 6 0 0 6 6 6 1 Chitin recognition protein LysM PF01476.20 EJP70667.1 - 0.0011 19.0 0.0 0.048 13.7 0.0 2.8 2 0 0 2 2 2 1 LysM domain rve_2 PF13333.6 EJP70667.1 - 0.21 11.8 0.1 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Integrase core domain Pro_isomerase PF00160.21 EJP70668.1 - 1.1e-40 139.5 0.1 1.4e-40 139.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TEA PF01285.18 EJP70670.1 - 1.2e-26 92.5 0.0 2.9e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain DUF3504 PF12012.8 EJP70670.1 - 0.077 12.9 1.0 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) RRM_1 PF00076.22 EJP70671.1 - 7.9e-75 246.7 1.3 5.9e-18 64.4 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJP70671.1 - 5.8e-07 29.3 0.0 0.46 10.4 0.0 4.4 5 0 0 5 5 5 3 Occluded RNA-recognition motif RRM_7 PF16367.5 EJP70671.1 - 4.9e-06 26.6 0.0 7.4 6.8 0.0 4.8 4 0 0 4 4 4 3 RNA recognition motif Limkain-b1 PF11608.8 EJP70671.1 - 2.1e-05 24.5 0.2 1.5 9.0 0.0 5.3 5 1 0 5 5 5 1 Limkain b1 RRM_3 PF08777.11 EJP70671.1 - 3e-05 24.0 0.3 3.6 7.7 0.0 4.5 4 1 0 4 4 4 2 RNA binding motif RRM_Rrp7 PF17799.1 EJP70671.1 - 7.8e-05 22.5 0.1 2.8 7.7 0.0 4.4 4 0 0 4 4 4 1 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 EJP70671.1 - 0.0013 18.7 0.0 3.5 7.7 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Smg4_UPF3 PF03467.15 EJP70671.1 - 0.0025 17.9 0.0 1.4 8.9 0.0 3.9 3 0 0 3 3 3 1 Smg-4/UPF3 family Glyco_tranf_2_3 PF13641.6 EJP70672.1 - 4.4e-19 69.3 0.0 6.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EJP70672.1 - 6.1e-18 65.4 0.3 6.1e-18 65.4 0.3 2.9 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EJP70672.1 - 4.3e-12 45.9 0.0 6.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EJP70672.1 - 7.7e-12 45.3 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 EJP70672.1 - 2.3e-09 36.4 4.7 1.3e-07 30.6 0.0 2.9 2 1 2 4 4 4 2 Cellulose synthase Chitin_synth_2 PF03142.15 EJP70672.1 - 0.019 13.6 0.1 0.019 13.6 0.1 2.2 2 2 1 3 3 3 0 Chitin synthase Glyco_hydro_12 PF01670.16 EJP70673.1 - 2.3e-15 57.2 5.9 3e-14 53.5 5.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Dynein_light PF01221.18 EJP70674.1 - 7.4e-40 135.2 1.2 8.3e-40 135.0 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 EJP70674.1 - 0.055 13.3 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 48 p450 PF00067.22 EJP70675.1 - 5.5e-62 210.0 0.0 1.1e-61 209.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Helicase_C PF00271.31 EJP70676.1 - 3.6e-26 91.7 0.0 5.2e-25 87.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP70676.1 - 1.3e-25 90.2 0.1 2.7e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 EJP70676.1 - 4.3e-05 23.6 0.1 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma70_ner PF04546.13 EJP70676.1 - 0.083 12.8 16.0 0.34 10.8 0.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region RNase_H2_suC PF08615.11 EJP70676.1 - 0.35 11.0 2.6 2 8.6 0.2 2.5 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) NAM-associated PF14303.6 EJP70676.1 - 0.41 11.4 0.1 0.41 11.4 0.1 2.7 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain TSA PF03249.13 EJP70676.1 - 0.97 8.1 5.0 11 4.6 0.1 2.1 2 0 0 2 2 2 0 Type specific antigen DUF4611 PF15387.6 EJP70676.1 - 4 7.7 15.5 0.45 10.8 8.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RasGAP PF00616.19 EJP70676.1 - 5.2 6.7 14.8 7.2 6.3 2.1 2.4 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase TRAP_alpha PF03896.16 EJP70676.1 - 7.8 5.6 12.0 0.17 11.1 3.8 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2401 PF10287.9 EJP70677.1 - 1.2e-87 293.3 0.2 1.7e-87 292.8 0.2 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EJP70677.1 - 1.9e-26 92.2 0.0 4.9e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) tRNA-synt_2 PF00152.20 EJP70678.1 - 1.2e-66 225.0 0.0 1.5e-54 185.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJP70678.1 - 1.6e-06 28.0 0.1 2.9e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EJP70678.1 - 5e-06 26.2 0.0 0.0018 17.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Actin PF00022.19 EJP70679.1 - 6.5e-148 492.7 0.0 7.4e-148 492.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EJP70679.1 - 6.3e-05 22.0 0.0 0.089 11.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein UDG PF03167.19 EJP70680.1 - 3.5e-20 72.5 0.0 5.8e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Fis1_TPR_N PF14852.6 EJP70680.1 - 0.18 11.5 0.9 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat DUF1117 PF06547.12 EJP70680.1 - 1.4 9.5 4.9 0.4 11.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) UDPGP PF01704.18 EJP70681.1 - 8e-56 189.4 0.0 1e-55 189.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EJP70681.1 - 0.027 14.8 0.0 0.094 13.1 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain Fer4_20 PF14691.6 EJP70681.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Raffinose_syn PF05691.12 EJP70682.1 - 1.4e-57 195.1 2.6 1.7e-54 184.9 2.6 3.2 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Peptidase_M16 PF00675.20 EJP70683.1 - 4.6e-57 192.2 0.4 1.4e-55 187.4 0.2 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EJP70683.1 - 4.4e-34 118.1 0.1 7.5e-33 114.1 0.0 2.5 3 0 0 3 3 3 1 Peptidase M16 inactive domain MTD PF01993.18 EJP70683.1 - 0.095 12.0 0.0 1.6 8.0 0.0 2.2 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase RbsD_FucU PF05025.13 EJP70683.1 - 0.14 12.6 0.1 0.87 10.0 0.0 2.2 2 0 0 2 2 2 0 RbsD / FucU transport protein family fn3 PF00041.21 EJP70684.1 - 2.6e-07 30.9 0.0 8.9e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain LNS2 PF08235.13 EJP70685.1 - 3.6e-94 314.5 0.0 5.1e-94 314.0 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EJP70685.1 - 8e-43 144.6 0.0 2.3e-42 143.1 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EJP70685.1 - 0.002 17.8 0.1 0.25 10.9 0.0 2.6 3 0 0 3 3 3 2 HAD superfamily, subfamily IIIB (Acid phosphatase) Histidinol_dh PF00815.20 EJP70686.1 - 2.9e-160 533.8 4.6 4.7e-160 533.1 4.6 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EJP70686.1 - 6.2e-24 83.6 0.0 1.7e-23 82.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EJP70686.1 - 4.7e-12 46.2 2.5 5.5e-12 46.0 0.8 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Cas_Csx9 PF09658.10 EJP70686.1 - 0.089 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) TFIID-31kDa PF02291.15 EJP70687.1 - 2.2e-42 144.0 0.0 2.8e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AMP-binding PF00501.28 EJP70688.1 - 2.1e-62 211.1 0.0 2.6e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP70688.1 - 7.3e-07 30.1 0.0 1.6e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_S8 PF00082.22 EJP70689.1 - 2.6e-26 92.6 13.1 4.1e-26 91.9 13.1 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJP70689.1 - 9.3e-20 71.1 0.0 1.7e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Vps53_N PF04100.12 EJP70690.1 - 1.2e-108 363.5 2.3 2.2e-108 362.6 2.3 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 EJP70690.1 - 2.8e-07 30.1 4.7 4.9e-07 29.3 4.7 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 EJP70690.1 - 1e-05 24.6 2.6 0.0011 17.9 0.0 3.2 3 1 0 3 3 3 1 RINT-1 / TIP-1 family DUF2451 PF10474.9 EJP70690.1 - 1.5e-05 24.9 0.2 3.6e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.11 EJP70690.1 - 0.015 14.2 8.7 0.01 14.8 6.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Zw10 PF06248.13 EJP70690.1 - 0.03 12.9 10.7 0.0048 15.5 6.2 1.8 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 FliG_N PF14842.6 EJP70690.1 - 0.041 14.4 0.4 0.41 11.2 0.1 2.7 2 0 0 2 2 2 0 FliG N-terminal domain DUF5082 PF16888.5 EJP70690.1 - 0.053 13.8 5.2 0.66 10.3 1.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF5481 PF17578.2 EJP70690.1 - 0.076 13.4 0.1 0.78 10.2 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5481) DUF3919 PF13057.6 EJP70690.1 - 0.099 12.2 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) SesA PF17107.5 EJP70690.1 - 0.23 11.6 3.9 0.82 9.9 1.3 3.0 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases XhlA PF10779.9 EJP70690.1 - 0.28 11.4 3.0 0.88 9.8 1.0 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 EJP70690.1 - 0.94 9.7 3.9 1.3 9.3 1.0 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 EJP70690.1 - 1.1 9.3 4.5 0.5 10.4 0.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Dynactin_p22 PF07426.11 EJP70690.1 - 1.2 9.0 7.6 11 5.9 7.6 2.5 1 1 0 1 1 1 0 Dynactin subunit p22 DivIC PF04977.15 EJP70690.1 - 3.7 7.4 7.1 19 5.1 0.1 3.3 3 0 0 3 3 3 0 Septum formation initiator COG2 PF06148.11 EJP70690.1 - 6.7 6.8 7.8 49 4.0 4.6 3.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 EJP70690.1 - 7 6.7 8.5 14 5.7 6.6 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pyr_redox_2 PF07992.14 EJP70691.1 - 1.2e-50 172.4 0.3 1.4e-50 172.2 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJP70691.1 - 1.1e-18 67.6 0.0 4.4e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJP70691.1 - 1.4e-18 67.2 0.5 7.1e-16 58.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EJP70691.1 - 1.4e-05 25.5 0.0 0.0059 17.0 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EJP70691.1 - 1.5e-05 25.1 0.1 0.03 14.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EJP70691.1 - 0.00012 21.4 0.0 0.00038 19.8 0.0 1.8 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EJP70691.1 - 0.00014 21.4 0.1 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EJP70691.1 - 0.00026 20.7 0.3 0.64 9.5 0.0 3.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.22 EJP70691.1 - 0.00048 19.3 4.7 0.14 11.2 0.1 4.1 3 2 1 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.6 EJP70691.1 - 0.0029 16.8 0.2 0.051 12.7 0.1 2.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EJP70691.1 - 0.0063 16.6 0.2 8.1 6.5 0.0 3.2 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EJP70691.1 - 0.016 13.9 0.2 2.5 6.7 0.1 3.0 3 1 1 4 4 4 0 HI0933-like protein NAD_binding_9 PF13454.6 EJP70691.1 - 0.018 15.0 0.1 2.8 7.9 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EJP70691.1 - 0.021 14.1 1.6 2.5 7.3 0.1 2.9 2 1 1 3 3 3 0 FAD binding domain FAD_binding_2 PF00890.24 EJP70691.1 - 0.024 13.7 5.0 0.14 11.2 0.3 3.3 3 1 1 4 4 4 0 FAD binding domain Trp_halogenase PF04820.14 EJP70691.1 - 0.11 11.4 0.1 0.46 9.3 0.0 2.0 3 0 0 3 3 3 0 Tryptophan halogenase Peptidase_M43 PF05572.13 EJP70692.1 - 6.8e-19 68.3 0.5 1e-18 67.7 0.5 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 EJP70692.1 - 0.00018 21.4 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 EJP70692.1 - 0.0004 20.6 1.4 0.00074 19.7 1.4 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.16 EJP70692.1 - 0.00071 19.7 0.1 0.0025 17.9 0.1 2.0 2 0 0 2 2 2 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.6 EJP70692.1 - 0.0037 16.9 0.1 0.0085 15.8 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EJP70692.1 - 0.0065 17.0 1.3 0.094 13.2 0.3 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EJP70692.1 - 0.0086 15.3 0.1 0.051 12.8 0.0 2.0 2 0 0 2 2 2 1 Met-zincin Peptidase_M66 PF10462.9 EJP70692.1 - 0.0093 15.0 0.2 0.015 14.3 0.1 1.5 1 1 0 1 1 1 1 Peptidase M66 Astacin PF01400.24 EJP70692.1 - 0.012 15.3 0.3 0.064 12.9 0.0 2.0 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.6 EJP70692.1 - 0.073 13.0 0.2 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like SIP PF04954.13 EJP70692.1 - 0.11 13.1 0.1 0.19 12.3 0.1 1.4 1 0 0 1 1 1 0 Siderophore-interacting protein IMPDH PF00478.25 EJP70693.1 - 2.6e-127 424.6 4.2 3e-127 424.4 4.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EJP70693.1 - 2e-14 53.7 0.1 5.7e-07 29.9 0.1 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EJP70693.1 - 1.8e-09 37.1 2.1 9.3e-08 31.5 1.1 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 EJP70693.1 - 2.4e-06 27.2 5.9 0.032 13.6 6.1 2.6 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 EJP70693.1 - 0.00083 18.9 4.3 0.01 15.3 2.3 2.7 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 EJP70693.1 - 0.022 14.0 3.0 0.16 11.3 0.7 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Acetyltransf_1 PF00583.25 EJP70694.1 - 2e-12 47.4 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EJP70694.1 - 4.7e-08 32.9 0.0 7.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EJP70694.1 - 1.2e-06 28.9 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJP70694.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EJP70694.1 - 0.0037 18.0 0.0 0.0055 17.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L36 PF00444.18 EJP70695.1 - 3.2e-22 78.4 10.9 4.2e-22 78.0 10.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_L35p PF01632.19 EJP70695.1 - 0.21 12.1 5.2 0.49 10.9 5.2 1.7 1 1 0 1 1 1 0 Ribosomal protein L35 Nudix_N_2 PF14803.6 EJP70696.1 - 0.2 11.6 1.4 0.42 10.6 1.4 1.6 1 0 0 1 1 1 0 Nudix N-terminal PH_6 PF15406.6 EJP70697.1 - 1.7e-34 118.4 2.9 1.7e-34 118.4 2.9 3.8 4 1 0 4 4 4 1 Pleckstrin homology domain PH PF00169.29 EJP70697.1 - 0.00013 22.4 0.0 0.00036 21.0 0.0 1.8 1 0 0 1 1 1 1 PH domain YHS PF04945.13 EJP70697.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 YHS domain HATPase_c PF02518.26 EJP70698.1 - 2e-23 83.0 0.2 3.8e-23 82.1 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EJP70698.1 - 3e-20 72.5 0.1 5.8e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 EJP70698.1 - 3.7e-12 46.5 0.0 1.6e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 EJP70698.1 - 3.3e-09 36.7 0.1 1.1e-08 35.1 0.1 2.0 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 EJP70698.1 - 7.6e-08 32.3 0.1 2.3e-07 30.7 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EJP70698.1 - 5.8e-06 26.5 0.0 3.8e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 EJP70698.1 - 6.4e-05 23.2 0.3 0.0002 21.6 0.3 1.8 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.6 EJP70698.1 - 0.0022 18.3 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 2 GAF domain HATPase_c_3 PF13589.6 EJP70698.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 EJP70698.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.9 1 0 0 1 1 1 0 PAS domain Aldedh PF00171.22 EJP70700.1 - 2.2e-166 553.9 0.5 2.5e-166 553.7 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 EJP70701.1 - 6e-34 117.3 1.2 8.2e-34 116.9 1.2 1.3 1 0 0 1 1 1 1 Ribosome recycling factor RAP1 PF07218.11 EJP70701.1 - 0.2 9.9 0.4 0.2 9.9 0.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Metallophos PF00149.28 EJP70703.1 - 1.9e-34 120.0 0.1 2.8e-34 119.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EJP70703.1 - 4.1e-16 59.1 0.0 7.5e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain MutS_I PF01624.20 EJP70703.1 - 0.13 12.5 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 MutS domain I Hydrolase_like PF13242.6 EJP70704.1 - 3.9e-05 23.6 0.1 7.6e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EJP70704.1 - 0.21 11.7 0.0 0.87 9.6 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SUR7 PF06687.12 EJP70705.1 - 4.2e-27 95.2 7.2 5.4e-27 94.8 7.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family LapA_dom PF06305.11 EJP70705.1 - 0.84 9.5 0.0 0.84 9.5 0.0 3.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain WD40 PF00400.32 EJP70706.1 - 2.7e-14 53.3 3.6 6.5e-05 23.6 0.0 8.1 9 0 0 9 9 9 3 WD domain, G-beta repeat ADH_N PF08240.12 EJP70708.1 - 7.9e-27 93.3 1.6 1.5e-26 92.4 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJP70708.1 - 8.9e-13 48.4 0.0 1.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EJP70708.1 - 2.8e-06 27.0 0.4 5.6e-05 22.7 0.4 2.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 EJP70708.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain S1-like PF14444.6 EJP70708.1 - 0.13 12.2 0.0 3.3 7.7 0.0 2.9 3 0 0 3 3 3 0 S1-like Rad60-SLD PF11976.8 EJP70709.1 - 1.2e-16 60.3 0.3 3.3e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EJP70709.1 - 0.00045 19.9 0.0 0.00092 18.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family CENP-Q PF13094.6 EJP70709.1 - 0.018 15.3 1.2 0.018 15.3 1.2 2.4 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit LSM PF01423.22 EJP70710.1 - 1.9e-19 69.1 0.2 2.2e-19 68.9 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EJP70710.1 - 0.00011 22.3 0.1 0.00012 22.1 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EJP70710.1 - 0.0015 18.6 0.1 0.0018 18.3 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Mrx7 PF10906.8 EJP70712.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 MIOREX complex component 7 Cys_Met_Meta_PP PF01053.20 EJP70713.1 - 1.2e-58 198.5 0.0 2.4e-58 197.5 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.18 EJP70714.1 - 0.026 13.6 0.1 0.043 12.8 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ring_hydroxyl_A PF00848.19 EJP70715.1 - 2.5e-20 73.4 4.7 1.6e-17 64.2 4.7 2.2 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EJP70715.1 - 7.8e-15 54.6 0.1 1.5e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.24 EJP70716.1 - 1.1e-43 150.2 0.4 1.3e-43 150.0 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EJP70716.1 - 3.2e-07 29.8 0.2 0.0037 16.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EJP70716.1 - 4.5e-07 30.0 0.2 2.6e-06 27.6 0.1 2.3 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP70716.1 - 5.5e-05 22.5 0.0 0.015 14.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJP70716.1 - 0.00014 21.0 0.0 0.11 11.5 0.0 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 EJP70716.1 - 0.0009 18.8 0.0 0.045 13.2 0.0 2.4 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 EJP70716.1 - 0.0034 16.7 0.0 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJP70716.1 - 0.004 16.4 0.1 0.0075 15.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EJP70716.1 - 0.016 14.5 0.1 0.043 13.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EJP70716.1 - 0.031 14.3 0.3 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EJP70716.1 - 0.034 14.7 0.1 0.11 13.1 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP70716.1 - 0.037 12.7 0.1 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 EJP70716.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EJP70716.1 - 0.1 12.9 0.2 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.23 EJP70716.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KH_1 PF00013.29 EJP70717.1 - 1.7e-42 143.0 5.9 1.5e-17 63.2 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EJP70717.1 - 7.2e-13 48.2 3.5 0.0022 17.8 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EJP70717.1 - 2.5e-07 30.5 2.0 0.17 11.7 0.1 3.5 3 1 0 3 3 3 3 KH domain MOEP19 PF16005.5 EJP70717.1 - 4.6e-05 23.3 0.0 0.073 13.1 0.0 3.2 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 EJP70717.1 - 0.00023 21.2 8.3 0.17 11.9 0.2 3.5 3 0 0 3 3 3 3 NusA-like KH domain CENP-K PF11802.8 EJP70718.1 - 6.2e-11 42.4 2.9 0.00047 19.8 0.0 2.4 2 1 0 2 2 2 2 Centromere-associated protein K Sec2p PF06428.11 EJP70718.1 - 0.53 10.3 9.3 2.2 8.3 1.9 2.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p KLRAQ PF10205.9 EJP70718.1 - 0.56 10.5 11.0 7.3 6.9 5.7 2.8 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein CDC37_N PF03234.14 EJP70718.1 - 3.9 8.4 7.9 1 10.2 2.2 2.6 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding Fez1 PF06818.15 EJP70718.1 - 4.5 7.7 10.8 17 5.8 10.8 2.1 1 1 0 1 1 1 0 Fez1 CDH-cyt PF16010.5 EJP70719.1 - 1.7e-08 34.4 1.7 3e-08 33.6 1.7 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 EJP70719.1 - 3.2e-05 23.6 2.4 3.2e-05 23.6 2.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 EJP70719.1 - 0.003 17.7 12.1 0.003 17.7 12.1 2.1 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EJP70719.1 - 0.75 9.9 17.2 1.6 8.9 13.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) dUTPase PF00692.19 EJP70720.1 - 1.3e-45 154.3 0.0 1.6e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 EJP70720.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.12 EJP70721.1 - 3e-12 46.4 0.0 6.2e-12 45.4 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EJP70721.1 - 1.9e-09 37.3 0.4 9.6e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase PCNA_N PF00705.18 EJP70722.1 - 2.5e-57 192.0 3.8 4.9e-57 191.1 3.8 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EJP70722.1 - 1.1e-49 167.8 0.0 6.4e-49 165.4 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EJP70722.1 - 1.6e-08 34.3 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EJP70722.1 - 4.7e-06 25.9 0.2 0.00018 20.7 0.2 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 EJP70722.1 - 0.00075 18.7 0.1 0.0023 17.1 0.1 1.7 2 0 0 2 2 2 1 Hus1-like protein DNA_pol3_beta_3 PF02768.15 EJP70722.1 - 0.093 12.6 0.1 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain AMA-1 PF02430.15 EJP70722.1 - 0.11 11.4 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Vezatin PF12632.7 EJP70723.1 - 1.3e-68 231.4 0.1 3e-68 230.2 0.0 1.6 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes DUF92 PF01940.16 EJP70723.1 - 0.042 13.2 0.5 0.077 12.4 0.5 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 DmsC PF04976.12 EJP70723.1 - 0.069 12.6 0.8 0.11 12.0 0.8 1.2 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) HAD_2 PF13419.6 EJP70724.1 - 1.4e-15 57.8 0.0 2.1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP70724.1 - 7.5e-11 42.7 0.1 9.2e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJP70724.1 - 0.00052 20.5 0.0 0.00061 20.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP70724.1 - 0.00068 19.6 0.1 0.0016 18.5 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EJP70724.1 - 0.00081 19.5 0.0 0.0019 18.3 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase D-ser_dehydrat PF14031.6 EJP70725.1 - 7.2e-21 74.7 0.1 3.4e-20 72.5 0.1 2.1 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EJP70725.1 - 3.1e-10 40.1 0.0 4.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HTH_1 PF00126.27 EJP70725.1 - 3 7.9 4.7 21 5.2 0.2 3.0 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family Zn_clus PF00172.18 EJP70726.1 - 0.00052 20.1 9.4 0.0012 19.0 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ig_C19orf38 PF17737.1 EJP70726.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Ig domain in C19orf38 (HIDE1) DUF4349 PF14257.6 EJP70728.1 - 1.5 8.2 10.2 0.54 9.7 1.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) zf-RING_2 PF13639.6 EJP70729.1 - 1.3e-10 41.4 3.8 2.1e-10 40.7 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EJP70729.1 - 3.8e-08 33.5 1.9 7e-08 32.7 1.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EJP70729.1 - 5.6e-08 32.5 4.4 2.5e-07 30.4 4.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EJP70729.1 - 5.1e-06 26.5 0.3 9.4e-06 25.6 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EJP70729.1 - 3.2e-05 23.9 1.4 5.5e-05 23.1 0.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EJP70729.1 - 5.6e-05 22.9 2.9 9.6e-05 22.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJP70729.1 - 7.1e-05 22.7 2.1 0.00011 22.1 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EJP70729.1 - 9.4e-05 22.2 1.5 0.00018 21.3 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJP70729.1 - 0.0005 19.9 2.0 0.00088 19.1 2.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EJP70729.1 - 0.0046 16.7 0.1 0.013 15.3 0.1 1.8 1 1 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 EJP70729.1 - 0.0055 16.5 0.6 0.011 15.5 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 EJP70729.1 - 0.013 15.7 3.4 0.29 11.3 3.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EJP70729.1 - 0.016 14.8 0.2 0.033 13.8 0.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 EJP70729.1 - 0.073 13.0 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EJP70729.1 - 0.16 12.1 3.5 0.5 10.6 3.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Cullin PF00888.22 EJP70730.1 - 1.7e-24 86.4 0.0 2.8e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EJP70730.1 - 1.4e-19 70.4 0.3 4.5e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 zf-C2H2 PF00096.26 EJP70732.1 - 0.00054 20.3 4.5 0.24 11.9 0.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJP70732.1 - 0.027 15.3 5.3 3.3 8.8 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger NR_Repeat PF14046.6 EJP70732.1 - 0.13 12.4 4.6 0.32 11.2 3.9 2.2 1 1 0 1 1 1 0 Nuclear receptor repeat Pkr1 PF08636.10 EJP70733.1 - 5.2e-32 109.8 5.4 6.7e-32 109.5 5.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 MFS_2 PF13347.6 EJP70734.1 - 9.3e-11 40.9 5.4 9.3e-11 40.9 5.4 2.5 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 EJP70734.1 - 0.00043 19.3 0.0 0.00092 18.2 0.0 2.0 1 1 0 1 1 1 1 MFS_1 like family Gram_pos_anchor PF00746.21 EJP70734.1 - 6.3 6.8 9.7 1.8 8.5 0.0 3.6 4 0 0 4 4 4 0 LPXTG cell wall anchor motif RhoGEF PF00621.20 EJP70735.1 - 1.2e-30 107.1 0.0 2.8e-30 105.9 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 EJP70735.1 - 4.8e-12 46.0 0.9 3.6e-11 43.2 0.3 2.4 2 0 0 2 2 2 1 BAR domain LPD13 PF18825.1 EJP70735.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 Telomerase_RBD PF12009.8 EJP70736.1 - 2.1e-42 144.4 0.1 4.4e-42 143.4 0.1 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EJP70736.1 - 2.2e-12 47.0 0.0 7.7e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT_2 PF13813.6 EJP70737.1 - 1.2e-14 54.4 3.9 1.2e-14 54.4 3.9 2.7 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family F-box PF00646.33 EJP70738.1 - 8.2e-06 25.6 0.1 1.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EJP70738.1 - 0.057 13.3 0.4 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 F-box Zn_clus PF00172.18 EJP70739.1 - 3e-05 24.1 11.5 8.8e-05 22.5 11.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 EJP70742.1 - 1.1e-65 217.6 3.8 1.4e-23 82.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJP70742.1 - 0.0039 16.4 0.3 0.028 13.6 0.1 2.4 3 0 0 3 3 3 1 Gammaproteobacterial serine protease IU_nuc_hydro PF01156.19 EJP70743.1 - 7.2e-81 272.1 0.1 8.3e-81 271.9 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 EJP70744.1 - 1.7e-08 34.4 8.3 1.7e-08 34.4 8.3 2.2 2 0 0 2 2 2 1 RED-like protein N-terminal region Lsm_interact PF05391.11 EJP70744.1 - 0.09 12.3 0.1 0.31 10.6 0.1 2.0 1 0 0 1 1 1 0 Lsm interaction motif Herpes_ICP4_C PF03585.14 EJP70744.1 - 0.17 10.6 1.4 0.34 9.6 0.3 1.9 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein C-terminal region DUF2924 PF11149.8 EJP70744.1 - 0.33 11.4 2.9 0.31 11.4 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2924) IMS PF00817.20 EJP70745.1 - 1.4e-36 125.8 0.0 2.4e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EJP70745.1 - 2.4e-27 95.2 0.4 5.1e-27 94.1 0.4 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EJP70745.1 - 6.5e-12 46.2 0.0 1.7e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 EJP70745.1 - 9.8e-12 43.9 7.5 3.8e-07 29.3 1.1 3.6 3 0 0 3 3 3 2 Ubiquitin binding region BRCT_2 PF16589.5 EJP70745.1 - 7e-08 32.8 0.0 2.7e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain mCpol PF18182.1 EJP70745.1 - 7.4e-05 23.1 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 minimal CRISPR polymerase domain IMS_HHH PF11798.8 EJP70745.1 - 0.00021 21.4 0.2 0.0054 17.0 0.1 3.0 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.26 EJP70745.1 - 0.0011 19.3 0.0 0.0032 17.8 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EJP70745.1 - 0.0033 17.7 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain HHH_5 PF14520.6 EJP70745.1 - 0.056 14.1 0.1 0.16 12.6 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain MgtE_N PF03448.17 EJP70745.1 - 0.075 13.6 0.1 4.4 8.0 0.0 3.0 2 0 0 2 2 2 0 MgtE intracellular N domain Cdd1 PF11731.8 EJP70745.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus WSC PF01822.19 EJP70746.1 - 4.5e-18 65.2 8.3 6.1e-18 64.8 8.3 1.2 1 0 0 1 1 1 1 WSC domain SHR3_chaperone PF08229.11 EJP70747.1 - 2.4e-69 232.1 0.0 2.7e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF202 PF02656.15 EJP70747.1 - 0.078 13.4 1.8 13 6.3 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Mito_carr PF00153.27 EJP70748.1 - 2.3e-58 194.1 0.1 1.5e-18 66.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.15 EJP70749.1 - 2e-27 95.9 10.4 3e-27 95.3 10.4 1.3 1 1 0 1 1 1 1 TspO/MBR family AAA_16 PF13191.6 EJP70750.1 - 4.4e-14 53.2 0.0 2.4e-13 50.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJP70750.1 - 2.6e-12 47.2 0.0 7.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EJP70750.1 - 6.9e-11 42.7 0.0 4.8e-10 40.0 0.0 2.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 EJP70750.1 - 8e-07 29.0 0.0 2.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 EJP70750.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 EJP70750.1 - 1.8e-05 25.1 0.1 8.1e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EJP70750.1 - 0.00047 19.6 0.0 0.0017 17.8 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein AAA_30 PF13604.6 EJP70750.1 - 0.00099 18.9 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EJP70750.1 - 0.0019 17.8 0.0 0.0067 16.0 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 EJP70750.1 - 0.0094 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EJP70750.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 EJP70750.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EJP70750.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EJP70750.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Torsin PF06309.11 EJP70750.1 - 0.035 14.2 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 Torsin KAP_NTPase PF07693.14 EJP70750.1 - 0.035 13.3 0.0 0.079 12.2 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Rad17 PF03215.15 EJP70750.1 - 0.043 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 EJP70750.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 EJP70750.1 - 0.088 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_32 PF13654.6 EJP70750.1 - 0.091 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain SseB_C PF14581.6 EJP70750.1 - 0.096 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 SseB protein C-terminal domain RNA12 PF10443.9 EJP70750.1 - 0.11 11.2 0.0 0.29 9.8 0.0 1.6 2 0 0 2 2 2 0 RNA12 protein ATPase PF06745.13 EJP70750.1 - 0.19 11.0 0.1 0.67 9.3 0.0 1.8 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 EJP70750.1 - 0.22 10.7 0.0 0.69 9.1 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain Arrestin_N PF00339.29 EJP70751.1 - 6.8e-16 58.6 0.0 3.1e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EJP70751.1 - 0.0028 18.1 0.0 0.09 13.2 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain HSCB_C PF07743.13 EJP70752.1 - 1.2e-18 67.3 3.5 2.4e-18 66.4 3.5 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EJP70752.1 - 0.00012 22.2 0.1 0.00024 21.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain VWA_N2 PF16164.5 EJP70752.1 - 1.9 8.7 5.5 12 6.2 2.2 2.3 2 0 0 2 2 2 0 VWA N-terminal FMN_dh PF01070.18 EJP70753.1 - 9.9e-108 360.2 0.0 1.3e-107 359.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EJP70753.1 - 2.4e-19 69.2 0.0 6.7e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EJP70753.1 - 6.7e-05 22.2 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EJP70753.1 - 0.00076 18.6 0.0 0.0066 15.5 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.11 EJP70753.1 - 0.031 14.1 0.1 0.047 13.5 0.1 1.1 1 0 0 1 1 1 0 ATP11 protein DUF3712 PF12505.8 EJP70754.1 - 2.1e-23 83.0 2.1 2.1e-23 83.0 2.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) MNHE PF01899.16 EJP70754.1 - 0.0019 17.9 1.0 0.02 14.7 0.3 2.2 2 0 0 2 2 2 1 Na+/H+ ion antiporter subunit HCNGP PF07818.13 EJP70755.1 - 7.6e-28 97.0 0.0 1.4e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein SPX PF03105.19 EJP70755.1 - 3.5 7.4 9.0 4.3 7.2 9.0 1.3 1 0 0 1 1 1 0 SPX domain FKBP_C PF00254.28 EJP70756.1 - 4e-17 62.3 0.1 1.3e-11 44.6 0.0 2.3 1 1 1 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4148 PF13663.6 EJP70756.1 - 0.037 14.2 0.5 0.053 13.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) RPEL PF02755.15 EJP70757.1 - 8.3e-19 66.7 0.4 4e-08 32.7 0.1 2.4 2 0 0 2 2 2 2 RPEL repeat Myosin_head PF00063.21 EJP70758.1 - 6.3e-236 784.8 4.3 7.5e-236 784.5 4.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EJP70758.1 - 2.1e-48 164.5 0.0 4e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EJP70758.1 - 1.7e-12 46.8 0.2 3.9e-12 45.6 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP70758.1 - 2.3e-09 36.9 0.1 5.9e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJP70758.1 - 8e-08 31.8 0.0 2.2e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 EJP70758.1 - 0.0084 15.8 10.2 0.17 11.8 2.4 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.12 EJP70758.1 - 0.016 14.8 0.6 5.6 6.5 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SepF PF04472.12 EJP70758.1 - 0.032 14.5 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Cell division protein SepF AAA_22 PF13401.6 EJP70758.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EJP70758.1 - 0.092 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EJP70758.1 - 0.14 12.0 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 NACHT domain SH3_3 PF08239.11 EJP70758.1 - 0.2 12.0 0.8 0.58 10.5 0.8 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain DHHC PF01529.20 EJP70759.1 - 2.1e-30 105.6 0.5 3.6e-30 104.8 0.5 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase PGBA_C PF15437.6 EJP70759.1 - 0.076 13.4 4.4 0.15 12.4 4.4 1.5 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Glyco_transf_90 PF05686.12 EJP70760.1 - 6.3e-09 35.2 0.0 0.0035 16.3 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 DUF4153 PF13687.6 EJP70760.1 - 0.015 15.0 1.3 0.015 15.0 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) SWIRM-assoc_2 PF16496.5 EJP70762.1 - 0.0035 16.3 0.1 0.0035 16.3 0.1 2.3 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal BRCT_2 PF16589.5 EJP70762.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EJP70762.1 - 0.067 13.2 0.1 4.4 7.3 0.1 2.4 2 0 0 2 2 2 0 twin BRCT domain Serglycin PF04360.12 EJP70763.1 - 0.0074 16.2 1.3 0.0085 16.0 1.3 1.2 1 0 0 1 1 1 1 Serglycin DUF4719 PF15843.5 EJP70763.1 - 0.24 11.5 1.3 0.24 11.5 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) RAP1 PF07218.11 EJP70763.1 - 5.2 5.2 6.0 5.4 5.2 6.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DAHP_synth_2 PF01474.16 EJP70764.1 - 2.6e-202 672.1 0.0 2.9e-202 672.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Aldose_epim PF01263.20 EJP70765.1 - 1.4e-41 142.8 0.0 1.7e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PSD2 PF07624.11 EJP70766.1 - 0.0058 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1585) Sugar_tr PF00083.24 EJP70767.1 - 1e-111 374.0 17.1 1.2e-111 373.7 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP70767.1 - 1.3e-23 83.5 21.1 1.7e-14 53.6 2.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Rif1_N PF12231.8 EJP70768.1 - 1e-139 465.7 6.0 2.5e-139 464.4 2.3 2.2 2 0 0 2 2 2 2 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 EJP70769.1 - 5.3e-125 418.1 0.0 6e-125 417.9 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Chromo PF00385.24 EJP70770.1 - 1e-16 60.6 4.7 1.8e-16 59.7 4.7 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MTBP_C PF14920.6 EJP70770.1 - 0.0045 16.8 8.3 0.0072 16.1 8.3 1.3 1 0 0 1 1 1 1 MDM2-binding ELM2 PF01448.24 EJP70770.1 - 0.12 13.2 2.2 0.35 11.7 2.2 1.9 1 0 0 1 1 1 0 ELM2 domain SOG2 PF10428.9 EJP70770.1 - 0.53 9.4 8.1 0.67 9.1 8.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Nucleo_P87 PF07267.11 EJP70770.1 - 9.3 5.0 10.6 11 4.8 10.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Afi1 PF07792.12 EJP70770.1 - 9.5 6.7 9.3 4 7.9 0.6 2.4 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 EJP70770.1 - 10 4.8 12.2 11 4.7 12.2 1.2 1 0 0 1 1 1 0 Presenilin DUF1772 PF08592.11 EJP70771.1 - 1.2e-26 93.6 4.2 1.6e-26 93.3 4.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Acetyltransf_3 PF13302.7 EJP70772.1 - 1.4e-32 113.3 0.0 1.7e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP70772.1 - 0.012 15.9 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Ribosomal_L18A PF01775.17 EJP70773.1 - 3.9e-54 181.9 0.4 5e-54 181.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 EJP70774.1 - 4.8e-11 43.1 0.0 1.9e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 PCI domain BTB PF00651.31 EJP70775.1 - 4.8e-06 26.8 0.0 1.9e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Abhydrolase_1 PF00561.20 EJP70776.1 - 1.1e-06 28.5 0.0 0.00034 20.3 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EJP70776.1 - 7.3e-06 26.0 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJP70776.1 - 0.00034 20.0 0.0 0.034 13.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EJP70776.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 EJP70776.1 - 0.038 13.6 0.0 0.07 12.7 0.0 1.4 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase LRR_4 PF12799.7 EJP70777.1 - 7.2e-30 102.5 23.4 5.4e-09 36.2 1.2 6.3 4 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EJP70777.1 - 2e-19 69.1 24.5 3.2e-07 30.0 2.3 5.8 3 2 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 EJP70777.1 - 9.2e-15 54.6 14.9 2.7e-05 23.7 0.9 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EJP70777.1 - 0.0004 20.2 18.4 0.48 10.6 0.3 6.8 8 0 0 8 8 8 2 Leucine Rich repeat Mog1 PF04603.12 EJP70777.1 - 0.038 14.4 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Ran-interacting Mog1 protein LRR_1 PF00560.33 EJP70777.1 - 0.085 13.5 20.7 15 6.6 0.0 7.7 9 1 0 9 9 9 0 Leucine Rich Repeat DUF3760 PF12586.8 EJP70777.1 - 0.12 12.6 3.9 17 5.7 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3760) Serglycin PF04360.12 EJP70777.1 - 0.26 11.2 0.8 0.5 10.3 0.8 1.4 1 0 0 1 1 1 0 Serglycin CUE PF02845.16 EJP70778.1 - 3.2e-11 42.7 0.1 5.8e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 CUE domain PHA_synth_III_E PF09712.10 EJP70778.1 - 0.026 13.6 0.2 0.054 12.6 0.2 1.4 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Ribosomal_S10 PF00338.22 EJP70779.1 - 2e-27 95.3 0.3 2.4e-27 95.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4469 PF14734.6 EJP70779.1 - 0.033 14.4 0.1 0.048 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold zf-CCCH_4 PF18044.1 EJP70780.1 - 3.6e-09 36.2 3.3 6.3e-09 35.4 3.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EJP70780.1 - 2e-06 27.6 7.4 4e-06 26.7 7.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EJP70780.1 - 4.8e-06 26.4 2.4 8.6e-06 25.5 2.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EJP70780.1 - 0.036 14.8 0.5 0.07 13.8 0.5 1.5 1 0 0 1 1 1 0 Torus domain Nucleoporin_FG PF13634.6 EJP70780.1 - 0.048 14.5 132.8 1.6 9.6 26.7 5.9 3 1 3 6 6 6 0 Nucleoporin FG repeat region zf-CCCH_2 PF14608.6 EJP70780.1 - 0.6 10.7 4.3 1.2 9.8 4.3 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Methyltransf_8 PF05148.15 EJP70781.1 - 7.6e-56 189.4 0.0 7.5e-54 182.9 0.0 2.9 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EJP70781.1 - 0.00089 19.9 0.0 0.0029 18.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP70781.1 - 0.0049 17.5 0.1 0.12 13.1 0.1 2.6 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EJP70781.1 - 0.0073 16.3 4.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EJP70781.1 - 0.0087 15.6 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain tRNA-synt_1g PF09334.11 EJP70781.1 - 0.03 13.1 0.1 0.14 10.8 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (M) Methyltransf_31 PF13847.6 EJP70781.1 - 0.064 13.1 0.1 1.5 8.6 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain ATXN-1_C PF12547.8 EJP70781.1 - 0.072 13.4 0.8 17 5.8 0.3 2.7 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator Zip PF02535.22 EJP70781.1 - 2.2 7.4 10.1 8.9 5.4 9.6 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4050 PF13259.6 EJP70781.1 - 2.5 8.4 10.9 21 5.4 10.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4050) NPR3 PF03666.13 EJP70781.1 - 7 5.3 12.8 10 4.8 12.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 EJP70781.1 - 7.4 4.7 10.5 10 4.3 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Asp_protease PF09668.10 EJP70782.1 - 5.1e-62 207.2 0.5 8.2e-62 206.5 0.5 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EJP70782.1 - 2.5e-24 85.6 4.8 3.2e-24 85.3 0.1 2.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EJP70782.1 - 9.9e-12 45.3 1.0 4.3e-11 43.3 0.1 2.5 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 EJP70782.1 - 8e-10 38.3 0.1 1.6e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EJP70782.1 - 1.1e-08 34.8 0.2 2.9e-08 33.4 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 EJP70782.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EJP70782.1 - 0.00036 20.8 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 EJP70782.1 - 0.0066 16.3 0.3 0.024 14.5 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 EJP70782.1 - 0.025 14.3 0.1 4.2 7.2 0.0 2.8 2 0 0 2 2 2 0 CUE domain UN_NPL4 PF11543.8 EJP70782.1 - 0.034 14.6 0.0 0.085 13.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UBA_4 PF14555.6 EJP70782.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Pribosyltran PF00156.27 EJP70783.1 - 2.3e-14 53.2 1.1 3.4e-14 52.7 1.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOG1_N PF17835.1 EJP70784.1 - 4.3e-49 166.5 0.1 4.3e-49 166.5 0.1 2.2 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EJP70784.1 - 1.3e-28 98.8 1.7 3.4e-28 97.4 1.7 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EJP70784.1 - 3.3e-26 90.8 0.3 6.7e-26 89.8 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EJP70784.1 - 2.1e-15 56.8 0.0 4.3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJP70784.1 - 1.9e-08 34.0 0.0 4.5e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EJP70784.1 - 0.0073 16.2 2.4 2 8.3 0.0 3.6 4 1 0 4 4 4 2 RsgA GTPase AAA_16 PF13191.6 EJP70784.1 - 0.0081 16.6 0.1 0.62 10.4 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain Dynamin_N PF00350.23 EJP70784.1 - 0.01 15.9 1.0 2.9 7.9 0.0 2.9 2 1 1 3 3 3 0 Dynamin family Roc PF08477.13 EJP70784.1 - 0.11 12.8 0.0 0.68 10.2 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GDI PF00996.18 EJP70785.1 - 5.1e-193 641.5 0.0 5.7e-193 641.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EJP70785.1 - 0.02 15.1 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP70785.1 - 0.083 13.5 0.2 0.55 10.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MRP-L47 PF06984.13 EJP70786.1 - 1.7e-22 79.3 1.3 2.7e-22 78.7 1.3 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 EJP70786.1 - 0.2 11.1 0.6 0.31 10.5 0.6 1.2 1 0 0 1 1 1 0 Clc-like Glyco_hydro_45 PF02015.16 EJP70787.1 - 8.2e-76 254.6 15.1 1e-75 254.3 15.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 zf-H2C2_2 PF13465.6 EJP70788.1 - 6e-06 26.4 11.7 7e-06 26.2 1.1 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 EJP70788.1 - 0.00023 21.4 4.1 0.00041 20.6 4.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EJP70788.1 - 0.00025 21.6 15.1 0.024 15.5 5.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJP70788.1 - 0.033 14.5 3.1 3.4 8.1 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EJP70788.1 - 0.067 13.7 14.6 0.14 12.6 7.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type TMEM144 PF07857.12 EJP70789.1 - 0.036 13.0 0.0 0.037 13.0 0.0 1.0 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters F-box PF00646.33 EJP70790.1 - 0.00036 20.3 0.5 0.0011 18.8 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EJP70790.1 - 0.013 15.4 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 F-box Ysc84 PF04366.12 EJP70791.1 - 4.3e-28 97.6 0.0 7.2e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator RXT2_N PF08595.11 EJP70791.1 - 8.7 6.4 8.3 1.8 8.6 1.2 2.6 2 1 0 2 2 2 0 RXT2-like, N-terminal Actin PF00022.19 EJP70792.1 - 1.7e-17 63.1 0.0 9.5e-15 54.1 0.0 2.5 3 0 0 3 3 3 2 Actin MatE PF01554.18 EJP70793.1 - 1.9e-55 186.9 27.6 3.1e-32 111.4 7.6 2.5 2 0 0 2 2 2 2 MatE Tyr-DNA_phospho PF06087.12 EJP70794.1 - 3e-113 378.9 0.0 3.5e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Thioredoxin PF00085.20 EJP70795.1 - 6.9e-41 138.4 0.1 3.8e-24 84.6 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EJP70795.1 - 1.9e-10 40.9 0.0 1e-05 25.5 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EJP70795.1 - 4.3e-08 33.4 0.2 0.0039 17.5 0.0 4.6 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 EJP70795.1 - 5.8e-06 25.9 0.0 0.14 11.5 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EJP70795.1 - 2.1e-05 24.9 1.2 0.22 12.0 0.1 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EJP70795.1 - 0.013 15.6 0.6 0.067 13.4 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin-like UBN_AB PF14075.6 EJP70795.1 - 0.025 14.3 0.8 0.047 13.4 0.8 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain PLDc PF00614.22 EJP70796.1 - 2.6e-14 52.7 0.3 1.2e-06 28.5 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EJP70796.1 - 1.2e-13 51.1 0.1 7.5e-06 25.9 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain Hid1 PF12722.7 EJP70796.1 - 0.36 8.9 10.0 0.59 8.2 10.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF908 PF06012.12 EJP70796.1 - 3 7.2 5.4 4.6 6.6 5.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Acetyltransf_10 PF13673.7 EJP70797.1 - 3e-07 30.4 0.0 5.6e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP70797.1 - 1.8e-06 27.8 0.1 3.4e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EJP70797.1 - 2.1e-06 27.9 0.0 2.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP70797.1 - 5.1e-05 23.6 0.0 7.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribonuclease_T2 PF00445.18 EJP70798.1 - 3.1e-38 131.8 0.5 4.6e-38 131.3 0.5 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Sec62 PF03839.16 EJP70799.1 - 1.6e-70 237.0 1.3 1.6e-70 237.0 1.3 1.8 2 0 0 2 2 2 1 Translocation protein Sec62 DUF4006 PF13179.6 EJP70799.1 - 0.33 10.9 1.2 1.1 9.2 1.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF4006) SelP_N PF04592.14 EJP70799.1 - 7.1 6.0 14.0 14 5.0 14.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Med21 PF11221.8 EJP70800.1 - 1.2e-45 155.3 6.8 1.4e-45 155.1 6.8 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF4455 PF14643.6 EJP70800.1 - 0.00038 19.2 4.5 0.00043 19.1 1.2 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4455) GAS PF13851.6 EJP70800.1 - 0.018 14.4 6.9 0.49 9.7 0.1 2.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Med9 PF07544.13 EJP70800.1 - 0.026 14.6 3.7 0.051 13.7 1.9 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Spore_III_AB PF09548.10 EJP70800.1 - 0.028 14.5 2.2 0.039 14.1 2.2 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) AHSP PF09236.10 EJP70800.1 - 0.33 11.4 2.3 1.1 9.8 0.6 2.4 2 1 0 2 2 2 0 Alpha-haemoglobin stabilising protein HAUS-augmin3 PF14932.6 EJP70800.1 - 0.81 9.2 8.3 2.9 7.4 3.4 2.1 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 EJP70800.1 - 1.3 9.1 8.9 1.5 8.9 6.9 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 EJP70800.1 - 2.2 8.8 11.4 6.6 7.3 11.4 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region HAD_2 PF13419.6 EJP70801.1 - 9.3e-11 42.1 0.0 1.3e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJP70801.1 - 5.2e-10 40.0 0.0 1.5e-08 35.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJP70801.1 - 0.0032 17.5 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like SWIRM-assoc_2 PF16496.5 EJP70802.1 - 3.7 6.3 8.2 5.7 5.7 8.2 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal KH_1 PF00013.29 EJP70803.1 - 2.1e-30 104.4 0.2 6.1e-07 29.2 0.0 6.7 7 0 0 7 7 7 5 KH domain ResIII PF04851.15 EJP70804.1 - 9.2e-24 84.3 0.0 1.5e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EJP70804.1 - 5.1e-14 52.6 0.1 2.5e-12 47.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJP70804.1 - 5e-12 45.9 0.0 1.1e-11 44.8 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EJP70804.1 - 0.00025 20.8 0.0 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EJP70804.1 - 0.012 15.9 0.0 0.052 13.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EJP70804.1 - 0.03 13.6 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EJP70804.1 - 0.067 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EJP70804.1 - 0.079 11.9 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ERCC3_RAD25_C PF16203.5 EJP70804.1 - 0.098 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Myb_DNA-binding PF00249.31 EJP70805.1 - 0.019 15.2 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Eaf7 PF07904.13 EJP70806.1 - 2.6e-27 95.3 0.1 2.6e-27 95.3 0.1 2.1 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 CDC27 PF09507.10 EJP70806.1 - 0.97 8.8 16.1 1.5 8.1 16.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.15 EJP70806.1 - 1.3 7.7 3.4 1.5 7.6 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Cwf_Cwc_15 PF04889.12 EJP70806.1 - 6.5 6.4 22.7 3.1 7.5 18.8 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GCP_C_terminal PF04130.13 EJP70807.1 - 1.9e-69 234.5 0.1 5.6e-69 233.0 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EJP70807.1 - 6.3e-28 98.3 0.4 1.3e-27 97.3 0.4 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Rab5-bind PF09311.11 EJP70807.1 - 0.069 12.5 0.0 0.91 8.8 0.0 2.3 2 0 0 2 2 2 0 Rabaptin-like protein ATG101 PF07855.12 EJP70807.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 Autophagy-related protein 101 Acetyltransf_1 PF00583.25 EJP70808.1 - 9.6e-09 35.5 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EJP70808.1 - 1.1e-08 35.8 0.0 1.4e-08 35.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EJP70808.1 - 0.00095 19.2 0.1 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 EJP70808.1 - 0.0086 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_10 PF13673.7 EJP70808.1 - 0.03 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJP70808.1 - 0.034 14.6 0.0 0.058 13.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA_SAD PF07973.14 EJP70809.1 - 8.1e-06 25.8 0.5 1.6e-05 24.9 0.5 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EJP70809.1 - 0.006 15.1 0.0 0.0072 14.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DASH_Ask1 PF08655.10 EJP70810.1 - 4.8e-31 106.4 0.2 7.6e-31 105.8 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Ploopntkinase2 PF18747.1 EJP70810.1 - 0.12 11.7 0.4 0.32 10.2 0.0 1.8 2 1 0 2 2 2 0 P-loop Nucleotide Kinase2 F-protein PF00469.20 EJP70810.1 - 10 5.7 6.7 11 5.6 0.0 2.8 2 1 1 3 3 3 0 Negative factor, (F-Protein) or Nef Pkinase PF00069.25 EJP70812.1 - 9e-09 35.1 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EJP70812.1 - 2.8e-07 30.7 0.1 8.2e-07 29.2 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EJP70812.1 - 2.8e-06 26.8 0.0 3.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EJP70812.1 - 4.7e-06 26.4 0.5 9e-06 25.4 0.4 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EJP70812.1 - 0.00036 19.9 0.1 0.00057 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EJP70812.1 - 0.00087 18.7 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Seadorna_VP7 PF07387.11 EJP70812.1 - 0.0077 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 EJP70812.1 - 0.014 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EJP70812.1 - 0.046 13.0 0.0 0.094 12.0 0.0 1.5 1 1 1 2 2 2 0 Kinase-like Peptidase_S8 PF00082.22 EJP70813.1 - 6.3e-33 114.3 11.2 1e-32 113.6 11.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJP70813.1 - 1.6e-09 38.3 0.2 1.4e-08 35.2 0.2 2.2 1 1 0 1 1 1 1 Peptidase inhibitor I9 Beta-lactamase PF00144.24 EJP70814.1 - 9e-54 182.9 2.0 2e-53 181.8 2.0 1.6 1 0 0 1 1 1 1 Beta-lactamase Transp_cyt_pur PF02133.15 EJP70814.1 - 1.3e-21 76.9 36.3 2.2e-21 76.1 36.3 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Beta-lactamase2 PF13354.6 EJP70814.1 - 0.02 14.5 0.3 0.39 10.3 0.3 2.3 1 1 0 1 1 1 0 Beta-lactamase enzyme family adh_short_C2 PF13561.6 EJP70816.1 - 2.8e-10 40.1 0.7 3.9e-10 39.7 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP70816.1 - 3.9e-05 23.2 0.0 0.00018 21.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase AdoMet_Synthase PF01941.19 EJP70816.1 - 0.053 12.3 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) adh_short_C2 PF13561.6 EJP70817.1 - 3.7e-24 85.6 0.1 4.6e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP70817.1 - 1.9e-22 79.7 0.0 2.4e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP70817.1 - 1.4e-06 28.3 0.1 2.6e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 KR domain SicP-binding PF09119.10 EJP70817.1 - 0.17 11.8 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 SicP binding MAPEG PF01124.18 EJP70818.1 - 5.7e-12 45.7 1.4 6.8e-12 45.4 1.4 1.2 1 0 0 1 1 1 1 MAPEG family Iron_permease PF04120.12 EJP70819.1 - 8.3e-34 116.1 4.5 6.4e-14 51.8 0.0 4.2 4 0 0 4 4 4 4 Low affinity iron permease V_ATPase_I PF01496.19 EJP70819.1 - 0.13 10.2 0.1 1.1 7.1 0.0 2.2 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family DUF4658 PF15555.6 EJP70819.1 - 0.34 11.1 2.3 28 4.9 0.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4658) DUF2839 PF10999.8 EJP70819.1 - 4.2 7.8 8.1 0.79 10.1 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Fungal_trans_2 PF11951.8 EJP70820.1 - 4.4e-07 29.0 3.0 7.1e-07 28.4 3.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EJP70821.1 - 1.3e-32 113.1 23.4 1.3e-32 113.1 23.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP70821.1 - 9.9e-11 41.1 5.8 9.9e-11 41.1 5.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DAO PF01266.24 EJP70822.1 - 1.5e-33 116.8 0.0 1.8e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EJP70822.1 - 0.00024 21.1 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EJP70822.1 - 0.0046 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJP70822.1 - 0.083 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJP70822.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RIBIOP_C PF04950.12 EJP70823.1 - 1.6e-92 310.0 1.5 2.5e-92 309.4 0.0 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EJP70823.1 - 2e-27 95.1 0.0 4.7e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EJP70823.1 - 1.4e-05 25.4 0.1 5.5e-05 23.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EJP70823.1 - 2e-05 25.1 0.1 8.8e-05 22.9 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain NACHT PF05729.12 EJP70823.1 - 0.00024 21.1 0.1 0.0012 18.8 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 EJP70823.1 - 0.0003 21.2 0.0 0.00087 19.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EJP70823.1 - 0.00068 19.7 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJP70823.1 - 0.00073 19.1 0.0 0.056 13.0 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EJP70823.1 - 0.0014 19.2 0.0 0.0014 19.2 0.0 2.4 3 0 0 3 3 1 1 ABC transporter AAA_33 PF13671.6 EJP70823.1 - 0.0024 18.1 1.3 0.0042 17.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.9 EJP70823.1 - 0.0032 17.2 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 EJP70823.1 - 0.0041 17.5 0.1 0.013 15.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EJP70823.1 - 0.0094 16.2 0.5 0.038 14.2 0.0 2.4 2 0 0 2 2 1 1 AAA domain cobW PF02492.19 EJP70823.1 - 0.0095 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EJP70823.1 - 0.011 15.7 0.0 0.066 13.1 0.0 2.2 3 0 0 3 3 2 0 RsgA GTPase AAA_30 PF13604.6 EJP70823.1 - 0.012 15.4 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EJP70823.1 - 0.016 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 EJP70823.1 - 0.02 15.3 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EJP70823.1 - 0.021 14.8 0.2 0.076 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EJP70823.1 - 0.024 15.2 10.2 0.046 14.3 0.0 4.1 3 1 1 4 4 3 0 AAA domain NB-ARC PF00931.22 EJP70823.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 EJP70823.1 - 0.03 13.9 0.0 0.078 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EJP70823.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EJP70823.1 - 0.04 14.1 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EJP70823.1 - 0.069 13.2 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EJP70823.1 - 0.079 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 EJP70823.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 EJP70823.1 - 0.14 12.0 0.2 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Reticulon PF02453.17 EJP70824.1 - 1.9e-34 118.9 2.4 2.4e-34 118.6 2.4 1.1 1 0 0 1 1 1 1 Reticulon zf-MYND PF01753.18 EJP70825.1 - 1.1e-09 38.2 11.2 2e-09 37.4 11.2 1.4 1 0 0 1 1 1 1 MYND finger RabGAP-TBC PF00566.18 EJP70826.1 - 5.4e-47 160.2 0.0 1.5e-46 158.8 0.0 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ATG16 PF08614.11 EJP70826.1 - 0.00094 19.5 7.0 0.00094 19.5 7.0 4.4 5 0 0 5 5 5 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EJP70826.1 - 0.0016 19.0 5.2 0.0016 19.0 5.2 5.1 4 1 1 5 5 5 1 Apg6 coiled-coil region FapA PF03961.13 EJP70826.1 - 0.009 14.7 0.6 0.009 14.7 0.6 1.9 2 0 0 2 2 2 1 Flagellar Assembly Protein A PRK PF00485.18 EJP70826.1 - 0.061 13.0 2.9 0.041 13.6 0.5 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Tup_N PF08581.10 EJP70826.1 - 0.31 11.4 5.8 2.1 8.7 5.8 2.5 1 0 0 1 1 1 0 Tup N-terminal HALZ PF02183.18 EJP70826.1 - 1.6 9.0 7.7 0.72 10.1 1.6 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Fzo_mitofusin PF04799.13 EJP70826.1 - 4.6 6.8 6.6 14 5.2 6.6 1.8 1 0 0 1 1 1 0 fzo-like conserved region Ion_trans PF00520.31 EJP70827.1 - 3.6e-05 23.1 29.8 7.9e-05 22.0 29.8 1.5 1 1 0 1 1 1 1 Ion transport protein TAP42 PF04177.12 EJP70830.1 - 3.4e-97 325.4 0.0 3.9e-97 325.2 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family DNA_topoisoIV PF00521.20 EJP70831.1 - 3.1e-123 411.8 0.3 1.3e-122 409.8 0.0 2.1 2 1 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EJP70831.1 - 2.9e-46 156.9 2.3 2.9e-46 156.9 2.3 2.2 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EJP70831.1 - 4.6e-26 91.3 1.9 1.1e-25 90.1 1.9 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EJP70831.1 - 4.4e-12 46.5 0.3 1.4e-11 44.9 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EJP70831.1 - 1.7e-06 28.1 0.0 8.1e-06 26.0 0.0 2.2 1 0 0 1 1 1 1 Toprim domain DUF2341 PF10102.9 EJP70831.1 - 0.076 13.6 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) DUF761 PF05553.11 EJP70833.1 - 0.18 11.4 3.0 0.33 10.5 1.3 2.0 2 0 0 2 2 2 0 Cotton fibre expressed protein MFS_1 PF07690.16 EJP70834.1 - 7.3e-35 120.5 25.8 1.4e-28 99.9 4.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP70834.1 - 2e-10 40.1 4.7 2e-10 40.1 4.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EJP70834.1 - 0.49 9.2 18.6 0.016 14.1 4.2 3.5 2 1 1 3 3 3 0 MFS_1 like family Metallophos PF00149.28 EJP70835.1 - 3.2e-36 125.7 0.0 5.5e-35 121.7 0.1 2.4 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase HIT PF01230.23 EJP70836.1 - 1.6e-19 70.4 0.1 2.3e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 HIT domain GalP_UDP_tr_C PF02744.17 EJP70836.1 - 0.0029 17.3 0.0 0.0042 16.8 0.0 1.1 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 EJP70836.1 - 0.0097 16.4 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MFS_1 PF07690.16 EJP70837.1 - 1.3e-29 103.2 26.3 2.1e-21 76.3 15.7 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJP70837.1 - 0.0092 14.4 0.5 0.016 13.6 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EJP70837.1 - 0.86 7.8 7.6 0.038 12.3 0.8 2.1 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Myb_Cef PF11831.8 EJP70838.1 - 4.8e-52 176.9 9.7 4.8e-52 176.9 9.7 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EJP70838.1 - 1.1e-23 83.2 3.9 3.3e-12 46.4 0.8 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJP70838.1 - 3.6e-20 72.0 3.4 1.4e-14 54.1 2.3 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EJP70838.1 - 0.051 13.7 2.3 0.11 12.6 0.0 2.8 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.16 EJP70839.1 - 5.3e-41 140.7 80.5 2.2e-37 128.8 52.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP70839.1 - 1.2e-11 44.1 17.3 6e-10 38.6 10.6 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EJP70839.1 - 0.00023 19.7 15.1 0.00033 19.2 15.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EJP70839.1 - 3 6.0 5.7 2.3 6.4 0.4 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATP-grasp_3 PF02655.14 EJP70840.1 - 0.014 15.4 0.0 0.033 14.3 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain Methyltransf_24 PF13578.6 EJP70841.1 - 8.5e-12 46.0 0.0 1.9e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EJP70841.1 - 8.2e-11 41.5 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 EJP70841.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.5 1 1 0 1 1 1 0 Cephalosporin hydroxylase K_channel_TID PF07941.11 EJP70841.1 - 6.8 7.2 9.8 0.14 12.6 2.9 1.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DHQ_synthase PF01761.20 EJP70842.1 - 2.6e-53 180.9 0.0 3.8e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EJP70842.1 - 4.8e-12 46.1 0.0 7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Hexokinase_2 PF03727.16 EJP70843.1 - 5.9e-45 153.6 0.0 8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EJP70843.1 - 8.5e-44 149.8 0.0 1.2e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Collagen PF01391.18 EJP70843.1 - 0.12 12.2 1.4 0.22 11.3 1.4 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) GILT PF03227.16 EJP70844.1 - 1.9e-18 66.6 0.0 3e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DcpS PF05652.12 EJP70845.1 - 2e-34 118.5 0.0 3.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EJP70845.1 - 7.3e-32 110.2 0.0 1.1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SH3_1 PF00018.28 EJP70846.1 - 3.2e-05 23.4 0.4 6.7e-05 22.4 0.4 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJP70846.1 - 0.00012 21.8 0.1 0.00023 20.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Yip1 PF04893.17 EJP70846.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain DUF4690 PF15756.5 EJP70846.1 - 0.021 15.4 1.0 0.062 13.9 0.0 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 EJP70846.1 - 0.035 14.3 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Podoplanin PF05808.11 EJP70846.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Mid2 PF04478.12 EJP70846.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3112 PF11309.8 EJP70847.1 - 2e-12 47.1 10.6 1.1e-08 34.8 0.1 2.7 2 2 0 3 3 3 2 Protein of unknown function (DUF3112) DUF2070 PF09843.9 EJP70847.1 - 1.6 6.9 11.9 2.7 6.2 11.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Archaeal_AmoA PF12942.7 EJP70847.1 - 1.8 8.2 11.1 0.52 10.0 0.4 3.2 1 1 2 3 3 3 0 Archaeal ammonia monooxygenase subunit A (AmoA) Metallophos PF00149.28 EJP70848.1 - 3.6e-38 132.1 0.5 5.7e-38 131.5 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EJP70848.1 - 0.018 15.5 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Exo84_C PF16528.5 EJP70849.1 - 1.4e-80 269.9 0.1 1.4e-80 269.9 0.1 2.3 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EJP70849.1 - 1.3e-12 47.6 0.6 1.3e-12 47.6 0.6 2.1 2 0 0 2 2 2 1 Vps51/Vps67 TSC22 PF01166.18 EJP70849.1 - 0.53 10.6 2.9 38 4.7 0.1 3.1 2 0 0 2 2 2 0 TSC-22/dip/bun family MAS20 PF02064.15 EJP70851.1 - 5.6e-35 120.3 0.6 7.1e-35 119.9 0.6 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor Protocadherin PF08374.11 EJP70851.1 - 0.037 14.0 0.1 0.05 13.6 0.1 1.2 1 0 0 1 1 1 0 Protocadherin Wyosine_form PF08608.12 EJP70852.1 - 1.7e-25 89.1 0.0 3.6e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EJP70852.1 - 3.6e-22 79.5 0.1 1.3e-21 77.7 0.1 2.0 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EJP70852.1 - 9.4e-10 38.9 0.1 6.5e-08 32.9 0.0 3.0 2 1 0 2 2 2 1 Flavodoxin CDO_I PF05995.12 EJP70853.1 - 5.7e-38 129.9 0.0 7.3e-38 129.5 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EJP70853.1 - 0.042 13.3 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 PCO_ADO SLAC1 PF03595.17 EJP70854.1 - 1.1e-93 314.0 47.5 1.3e-93 313.8 47.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel NCA2 PF08637.10 EJP70855.1 - 7.9e-108 360.0 0.3 1.9e-107 358.8 0.1 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.6 EJP70855.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 FA_hydroxylase PF04116.13 EJP70856.1 - 1.8e-26 93.1 16.6 1.8e-26 93.1 16.6 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.19 EJP70857.1 - 8.3e-24 83.6 0.2 1.4e-23 82.9 0.2 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase bZIP_1 PF00170.21 EJP70858.1 - 3.4e-08 33.5 7.4 8.9e-08 32.1 7.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor Actin PF00022.19 EJP70859.1 - 2.9e-55 187.5 0.0 1.3e-52 178.8 0.0 2.4 1 1 0 1 1 1 1 Actin Acylphosphatase PF00708.18 EJP70859.1 - 0.4 11.1 3.0 7.3 7.1 0.2 3.0 3 0 0 3 3 3 0 Acylphosphatase JHD PF17811.1 EJP70859.1 - 5.9 7.5 11.8 13 6.4 5.4 3.0 3 0 0 3 3 3 0 Jumonji helical domain DASH_Dad4 PF08650.10 EJP70860.1 - 4.1e-32 110.0 7.1 4.7e-32 109.8 7.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 EJP70860.1 - 0.055 13.6 0.5 0.071 13.3 0.5 1.2 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor YL1_C PF08265.11 EJP70861.1 - 8e-15 54.3 0.1 1.3e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CTD PF12815.7 EJP70861.1 - 0.74 10.4 7.1 3.5 8.2 7.0 2.1 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Got1 PF04178.12 EJP70862.1 - 7.9e-15 55.3 12.0 9.7e-15 55.0 12.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.6 EJP70862.1 - 0.13 12.1 12.6 0.079 12.8 5.3 2.8 2 1 1 3 3 3 0 YrhK-like protein SdpI PF13630.6 EJP70862.1 - 6 7.1 11.1 7.5 6.8 2.2 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family Profilin PF00235.19 EJP70863.1 - 6.4e-46 155.7 1.1 7.1e-46 155.6 1.1 1.0 1 0 0 1 1 1 1 Profilin NST1 PF13945.6 EJP70864.1 - 2.5 8.2 10.4 1.4 9.0 7.9 1.8 2 0 0 2 2 2 0 Salt tolerance down-regulator Synaptobrevin PF00957.21 EJP70865.1 - 2.1e-14 53.1 0.7 3.1e-14 52.5 0.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EJP70865.1 - 8e-13 48.2 0.0 1.8e-12 47.1 0.0 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain adh_short PF00106.25 EJP70866.1 - 2.8e-24 85.7 0.0 9.2e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EJP70866.1 - 1.9e-11 44.0 0.0 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP70866.1 - 0.032 14.2 0.0 0.081 12.8 0.0 1.6 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.6 EJP70866.1 - 0.11 12.4 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 EJP70866.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sec63 PF02889.16 EJP70867.1 - 1.9e-136 453.3 0.2 5e-80 268.4 0.1 2.6 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 EJP70867.1 - 2.4e-50 170.7 0.3 3.6e-25 88.7 0.3 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EJP70867.1 - 2.7e-22 79.6 0.0 4.2e-11 43.2 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EJP70867.1 - 1.3e-16 60.9 0.3 2.1e-06 28.0 0.0 4.8 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EJP70867.1 - 1.4e-06 28.6 0.6 0.11 12.7 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EJP70867.1 - 1.4e-05 25.0 0.1 0.18 11.5 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EJP70867.1 - 0.00012 21.8 0.1 0.07 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EJP70867.1 - 0.00014 22.2 0.5 0.027 14.8 0.4 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EJP70867.1 - 0.00034 21.0 0.2 3.2 8.2 0.0 4.5 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 EJP70867.1 - 0.0036 17.5 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 EJP70867.1 - 0.019 14.0 0.0 1.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EJP70867.1 - 0.13 12.0 0.5 21 4.8 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein TniB PF05621.11 EJP70867.1 - 0.14 11.6 1.1 20 4.5 0.1 3.5 3 0 0 3 3 3 0 Bacterial TniB protein RTA1 PF04479.13 EJP70868.1 - 5.3e-56 189.5 8.1 8.4e-56 188.9 8.1 1.3 1 0 0 1 1 1 1 RTA1 like protein Ni_hydr_CYTB PF01292.20 EJP70868.1 - 3.3 7.3 18.8 2.9 7.4 6.1 2.8 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Fungal_trans_2 PF11951.8 EJP70869.1 - 1.7e-05 23.9 0.2 2.4e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MARVEL PF01284.23 EJP70869.1 - 0.0031 17.6 10.7 0.0031 17.6 10.7 2.6 3 1 0 3 3 3 1 Membrane-associating domain Oxidored-like PF09791.9 EJP70869.1 - 0.13 12.0 0.8 0.55 9.9 0.1 2.3 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal Fungal_trans_2 PF11951.8 EJP70871.1 - 2.2e-06 26.7 0.2 4.9e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP70871.1 - 7.1e-05 22.8 15.0 0.00015 21.8 15.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Intimin_C PF07979.11 EJP70871.1 - 0.034 14.6 0.2 0.11 13.0 0.1 1.8 2 0 0 2 2 2 0 Intimin C-type lectin domain Ras PF00071.22 EJP70872.1 - 9.3e-40 135.9 0.0 2.5e-37 128.0 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EJP70872.1 - 1.9e-31 108.7 0.0 2.7e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJP70872.1 - 9.2e-12 44.8 0.0 1.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJP70872.1 - 2e-05 24.7 0.0 3.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EJP70872.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RTP1_C2 PF10304.9 EJP70872.1 - 0.032 13.9 0.3 0.064 13.0 0.3 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 FeoB_N PF02421.18 EJP70872.1 - 0.22 11.0 0.0 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B SUR7 PF06687.12 EJP70873.1 - 1.3e-09 38.0 0.5 1.4e-09 37.9 0.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EJP70873.1 - 0.00038 20.4 4.5 0.00058 19.8 4.5 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 NnrU PF07298.11 EJP70873.1 - 0.0095 15.5 0.5 0.015 14.8 0.5 1.2 1 0 0 1 1 1 1 NnrU protein SecE PF00584.20 EJP70873.1 - 1.2 9.1 5.3 0.38 10.7 1.5 2.1 1 1 1 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DUF2157 PF09925.9 EJP70873.1 - 1.7 8.5 8.4 6.6 6.5 7.7 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) SHMT PF00464.19 EJP70874.1 - 5.3e-207 687.2 0.0 6.2e-207 686.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EJP70874.1 - 0.00074 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EJP70874.1 - 0.025 13.9 0.0 0.039 13.2 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EJP70874.1 - 0.1 11.9 0.1 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ferric_reduct PF01794.19 EJP70875.1 - 4e-17 62.5 12.0 4e-17 62.5 12.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EJP70875.1 - 4.7e-13 49.5 0.0 7.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EJP70875.1 - 7.8e-07 29.2 0.0 2.4e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain Suc_Fer-like PF06999.12 EJP70875.1 - 0.00097 19.1 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like NAD_binding_1 PF00175.21 EJP70875.1 - 0.0091 16.6 0.1 5.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RRM_1 PF00076.22 EJP70876.1 - 1.4e-09 37.7 0.0 2.6e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJP70876.1 - 9.5e-07 28.5 0.0 3.2e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJP70876.1 - 0.041 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RF-1 PF00472.20 EJP70877.1 - 8.7e-14 51.5 0.1 1.5e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 RF-1 domain Pkinase PF00069.25 EJP70878.1 - 1.3e-71 241.1 0.0 1.6e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70878.1 - 9.6e-29 100.4 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJP70878.1 - 2.3e-07 30.4 0.0 4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EJP70878.1 - 8.2e-05 21.5 0.0 0.00015 20.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EJP70878.1 - 0.00056 19.9 0.1 0.00089 19.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EJP70878.1 - 0.00095 18.6 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAP2_3 PF14378.6 EJP70879.1 - 1.5e-24 86.7 12.6 1.5e-24 86.7 12.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EJP70879.1 - 9.7e-11 41.6 14.7 1.4e-10 41.0 8.4 2.7 2 1 0 2 2 2 2 PAP2 superfamily PAP2_C PF14360.6 EJP70879.1 - 5.3 7.6 9.8 1.4 9.5 1.8 3.0 2 1 0 3 3 3 0 PAP2 superfamily C-terminal RNA_polI_A34 PF08208.11 EJP70880.1 - 1.1e-40 139.9 9.2 1.1e-40 139.9 9.2 5.9 3 1 2 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 EJP70881.1 - 6.2e-27 94.6 0.0 1e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 EJP70881.1 - 0.00096 19.4 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EJP70881.1 - 0.0018 18.5 0.0 0.097 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EJP70881.1 - 0.0035 17.0 0.4 0.025 14.3 0.2 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 EJP70881.1 - 0.029 14.3 0.1 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 EJP70881.1 - 0.03 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EJP70881.1 - 0.032 14.8 0.1 0.17 12.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EJP70881.1 - 0.086 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EJP70881.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Fungal_trans PF04082.18 EJP70882.1 - 2.7e-11 43.0 5.1 5.4e-11 42.0 5.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain LisH_2 PF16045.5 EJP70882.1 - 0.13 11.3 0.5 0.28 10.2 0.5 1.6 1 0 0 1 1 1 0 LisH Cytochrom_B558a PF05038.13 EJP70884.1 - 0.023 14.3 0.3 0.072 12.6 0.2 1.8 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Glyco_hydro_16 PF00722.21 EJP70885.1 - 1.9e-06 27.5 0.4 4.3e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF3573 PF12097.8 EJP70885.1 - 0.0049 15.8 0.0 0.0067 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) Pex2_Pex12 PF04757.14 EJP70886.1 - 1.2e-37 129.7 0.7 1.7e-37 129.2 0.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EJP70886.1 - 0.00052 20.1 4.2 0.001 19.1 4.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EJP70886.1 - 0.0051 16.8 1.5 0.015 15.3 1.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EJP70886.1 - 0.0098 15.8 1.5 0.02 14.8 1.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJP70886.1 - 0.091 12.6 4.4 0.15 11.9 1.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.18 EJP70887.1 - 7.9e-08 32.3 10.2 1.6e-07 31.3 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EJP70887.1 - 0.039 12.8 0.5 0.062 12.1 0.5 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain zf-RING_2 PF13639.6 EJP70889.1 - 5.5e-09 36.2 8.7 9.4e-09 35.5 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJP70889.1 - 1.2e-06 28.2 7.4 2.1e-06 27.4 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJP70889.1 - 1.1e-05 25.2 7.6 1.9e-05 24.5 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJP70889.1 - 3.6e-05 23.4 9.7 7.5e-05 22.4 9.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EJP70889.1 - 0.00014 22.1 6.5 0.00049 20.3 6.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EJP70889.1 - 0.00023 21.2 2.7 0.00047 20.2 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EJP70889.1 - 0.00034 20.5 6.0 0.00054 19.9 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EJP70889.1 - 0.011 15.7 7.3 0.035 14.1 7.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EJP70889.1 - 0.035 13.7 4.1 0.063 12.9 4.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EJP70889.1 - 0.93 9.4 9.1 1.8 8.5 9.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EJP70889.1 - 3.8 7.5 9.4 7 6.6 9.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Het-C PF07217.11 EJP70890.1 - 2.1e-232 772.7 0.1 2.6e-232 772.4 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.18 EJP70890.1 - 0.0026 17.8 0.0 0.046 13.7 0.0 2.3 2 0 0 2 2 2 1 Zinc dependent phospholipase C HMG_box PF00505.19 EJP70891.1 - 8.8e-07 29.3 0.3 8.8e-07 29.3 0.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EJP70891.1 - 0.00024 21.7 2.2 0.00043 20.8 0.1 2.3 2 0 0 2 2 2 1 HMG-box domain Amidohydro_1 PF01979.20 EJP70892.1 - 1.7e-75 254.5 1.1 2.4e-75 254.0 0.5 1.5 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 EJP70892.1 - 2.7e-56 189.1 2.0 5.3e-56 188.2 2.0 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 EJP70892.1 - 7.3e-40 135.3 0.1 1.7e-39 134.1 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 EJP70892.1 - 1.1e-39 134.4 0.4 3.5e-39 132.8 0.1 2.0 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 EJP70892.1 - 8.7e-09 35.4 0.5 6.8e-07 29.1 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Ada3 PF10198.9 EJP70893.1 - 3.3e-57 192.3 0.1 3.3e-57 192.3 0.1 2.7 4 0 0 4 4 4 1 Histone acetyltransferases subunit 3 NGP1NT PF08153.12 EJP70894.1 - 4.5e-48 162.7 0.5 7.6e-48 162.0 0.5 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EJP70894.1 - 6.9e-17 61.6 0.1 9.2e-13 48.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EJP70894.1 - 2e-05 24.2 0.1 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EJP70894.1 - 0.00015 21.8 2.7 0.049 13.7 0.1 4.0 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.27 EJP70894.1 - 0.00023 20.8 0.2 0.23 11.0 0.0 3.8 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EJP70894.1 - 0.0038 17.1 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EJP70894.1 - 0.015 14.8 0.1 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 EJP70894.1 - 0.07 13.3 0.1 6.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BSP_II PF05432.11 EJP70894.1 - 0.12 12.1 13.1 0.23 11.1 13.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) But2 PF09792.9 EJP70895.1 - 1.2e-59 200.8 1.0 4e-59 199.1 0.2 2.1 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain CAP_N PF01213.19 EJP70895.1 - 0.13 11.7 1.3 0.19 11.2 1.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3918 PF13056.6 EJP70895.1 - 0.27 10.9 0.3 0.41 10.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) PRIMA1 PF16101.5 EJP70895.1 - 2.2 8.3 5.5 3.9 7.5 5.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CCDC53 PF10152.9 EJP70896.1 - 5.6 7.4 7.9 2e+02 2.3 7.9 2.1 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Opi1 PF08618.10 EJP70897.1 - 0.073 12.3 3.6 0.088 12.0 3.6 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 adh_short_C2 PF13561.6 EJP70898.1 - 1.7e-51 175.0 0.0 3e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP70898.1 - 2.6e-42 144.5 0.1 3.4e-42 144.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP70898.1 - 1.5e-11 44.5 0.1 2.2e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EJP70898.1 - 0.006 16.0 0.0 0.022 14.1 0.0 2.0 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Pyr_redox_2 PF07992.14 EJP70898.1 - 0.009 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 EJP70898.1 - 0.028 13.9 0.1 0.064 12.7 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 EJP70898.1 - 0.072 12.3 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Aa_trans PF01490.18 EJP70899.1 - 4.3e-74 249.7 24.2 5.3e-74 249.4 24.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PhoLip_ATPase_C PF16212.5 EJP70899.1 - 5.4 6.7 12.0 1.8 8.3 0.3 2.9 3 1 0 3 3 3 0 Phospholipid-translocating P-type ATPase C-terminal Hydrophobin_2 PF06766.11 EJP70900.1 - 1e-44 150.3 17.8 1.2e-28 98.8 9.5 2.5 2 0 0 2 2 2 2 Fungal hydrophobin PT PF04886.12 EJP70900.1 - 0.0014 18.1 17.8 0.0014 18.1 17.8 6.2 2 2 1 3 3 3 2 PT repeat adh_short_C2 PF13561.6 EJP70902.1 - 1.1e-56 192.1 0.7 1.2e-56 191.9 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EJP70902.1 - 2.9e-47 160.7 0.1 3.5e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EJP70902.1 - 3.8e-09 36.7 2.7 5.8e-09 36.1 2.7 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EJP70902.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 EJP70902.1 - 0.093 12.8 0.5 0.15 12.2 0.5 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AMP-binding PF00501.28 EJP70903.1 - 5.1e-97 325.1 0.0 6.5e-97 324.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP70903.1 - 5.3e-10 40.1 0.2 1.1e-09 39.1 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Spt5-NGN PF03439.13 EJP70905.1 - 8.7e-23 80.0 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 EJP70905.1 - 1.8e-22 79.7 29.2 8.5e-16 58.3 15.7 4.8 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 EJP70905.1 - 2.4e-20 73.4 12.5 2.4e-20 73.4 12.5 3.4 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EJP70905.1 - 0.00039 20.2 19.0 0.0041 17.0 1.7 5.1 5 0 0 5 5 5 2 KOW motif DUF3912 PF13051.6 EJP70905.1 - 0.056 13.7 0.2 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) ADH_zinc_N PF00107.26 EJP70906.1 - 1.5e-28 99.4 0.0 2.4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJP70906.1 - 9.1e-13 49.4 0.0 1.4e-12 48.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJP70906.1 - 8.6e-07 28.8 0.5 8.2e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 EJP70906.1 - 0.013 15.7 2.9 0.02 15.1 1.8 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal adh_short PF00106.25 EJP70906.1 - 0.25 10.8 1.4 0.38 10.2 0.8 1.6 1 1 1 2 2 2 0 short chain dehydrogenase WD40 PF00400.32 EJP70907.1 - 7.6e-13 48.7 8.8 1.2e-05 26.0 0.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ZapB PF06005.12 EJP70908.1 - 0.0022 18.4 1.6 0.0022 18.4 1.6 3.0 2 1 1 3 3 3 1 Cell division protein ZapB UL21a PF17636.2 EJP70908.1 - 0.056 13.5 0.2 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Viral Unique Long protein 21a Cep57_CLD PF14073.6 EJP70908.1 - 0.13 12.3 8.8 0.077 13.0 4.7 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Filament PF00038.21 EJP70908.1 - 0.13 11.8 6.7 0.075 12.6 2.5 2.2 2 0 0 2 2 2 0 Intermediate filament protein DUF1043 PF06295.12 EJP70908.1 - 0.17 11.9 0.5 0.47 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Syntaxin-6_N PF09177.11 EJP70908.1 - 0.21 12.1 3.0 4.1 8.0 0.5 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1843 PF08898.10 EJP70908.1 - 0.23 12.0 1.7 12 6.5 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Spc7 PF08317.11 EJP70908.1 - 0.82 8.5 10.3 0.16 10.8 4.3 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein Laminin_II PF06009.12 EJP70908.1 - 0.93 9.5 4.2 0.56 10.2 1.3 2.0 2 0 0 2 2 2 0 Laminin Domain II DUF29 PF01724.16 EJP70908.1 - 0.99 9.6 5.9 4.9 7.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF29 BLOC1_2 PF10046.9 EJP70908.1 - 1.1 9.6 4.3 20 5.6 0.3 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 EJP70908.1 - 1.2 8.9 6.3 1.1 9.1 2.3 2.6 2 1 0 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 EJP70908.1 - 1.4 9.0 5.4 0.83 9.7 2.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 EJP70908.1 - 1.4 8.7 4.4 1.6 8.5 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 EJP70908.1 - 1.6 8.7 11.2 0.56 10.2 4.1 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EJP70908.1 - 1.7 8.7 3.4 6.8 6.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 EJP70908.1 - 1.9 8.6 11.0 0.46 10.6 1.5 3.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain V_ATPase_I PF01496.19 EJP70908.1 - 2.3 6.0 3.8 2.2 6.1 2.6 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FAM184 PF15665.5 EJP70908.1 - 4.1 7.1 11.7 1.8 8.3 5.2 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B APG6_N PF17675.1 EJP70908.1 - 7 7.2 19.0 0.21 12.1 7.3 3.4 2 2 0 2 2 2 0 Apg6 coiled-coil region DUF1748 PF08520.10 EJP70909.1 - 9.9e-33 111.9 0.1 1.2e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MFS_1 PF07690.16 EJP70910.1 - 3e-11 42.8 33.9 3e-11 42.8 33.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TerC PF03741.16 EJP70910.1 - 0.0032 17.2 0.1 0.0032 17.2 0.1 2.6 2 1 0 2 2 2 1 Integral membrane protein TerC family PSDC PF12588.8 EJP70911.1 - 1.1e-43 148.6 0.6 9e-43 145.6 0.0 2.4 3 0 0 3 3 3 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EJP70911.1 - 3.5e-26 92.0 0.0 4.9e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DnaT PF17948.1 EJP70911.1 - 0.18 11.5 1.1 2.9 7.6 0.2 2.5 2 0 0 2 2 2 0 DnaT DNA-binding domain PK PF00224.21 EJP70913.1 - 7e-169 561.2 1.9 8.7e-169 560.9 1.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EJP70913.1 - 2.7e-36 124.3 0.0 6.3e-36 123.2 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EJP70913.1 - 0.00071 18.8 0.4 0.0059 15.8 0.2 2.2 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EJP70913.1 - 0.02 13.9 0.0 0.32 9.9 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain MFS_1 PF07690.16 EJP70914.1 - 6.8e-44 150.2 20.5 6.8e-44 150.2 20.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP70914.1 - 3.3e-11 42.7 0.9 3.3e-11 42.7 0.9 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EJP70914.1 - 0.00014 20.5 6.3 0.00021 19.9 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EJP70914.1 - 0.0025 16.2 0.7 0.0025 16.2 0.7 2.8 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Beta-lactamase PF00144.24 EJP70915.1 - 1.6e-45 155.8 0.8 2.1e-45 155.4 0.8 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EJP70915.1 - 4.1e-05 24.0 0.0 0.00015 22.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) Pkinase PF00069.25 EJP70916.1 - 1.6e-44 152.2 0.0 1.1e-43 149.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70916.1 - 1.2e-29 103.4 0.0 1.8e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP70916.1 - 0.01 15.2 0.1 0.09 12.1 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUP PF06516.11 EJP70917.1 - 4.5e-126 420.3 0.0 5.7e-126 420.0 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Cation_ATPase_C PF00689.21 EJP70918.1 - 4.5e-43 147.1 3.9 4.5e-43 147.1 3.9 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EJP70918.1 - 1.4e-32 112.6 0.3 1.4e-32 112.6 0.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EJP70918.1 - 1.3e-21 76.4 0.0 3.9e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EJP70918.1 - 1.9e-17 64.3 0.1 2.2e-16 60.8 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EJP70918.1 - 1e-08 34.7 0.0 2.6e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJP70918.1 - 2.8e-06 27.3 0.1 0.00015 21.6 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 EJP70918.1 - 0.027 14.5 3.1 0.12 12.4 0.4 2.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Lipoprotein_21 PF14041.6 EJP70918.1 - 0.27 11.4 1.1 1.9 8.7 0.3 2.4 2 0 0 2 2 2 0 LppP/LprE lipoprotein ABC_membrane PF00664.23 EJP70919.1 - 1.2e-74 251.5 21.4 2.6e-38 132.2 9.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EJP70919.1 - 2.8e-53 180.1 0.0 2.5e-25 89.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EJP70919.1 - 7e-17 62.2 0.0 0.00082 19.3 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJP70919.1 - 1.3e-11 44.4 0.0 0.019 14.4 0.0 4.3 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJP70919.1 - 1e-07 31.6 1.8 0.0047 16.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJP70919.1 - 4.2e-07 30.0 0.1 0.002 18.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EJP70919.1 - 6.4e-07 29.9 0.2 0.054 13.9 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EJP70919.1 - 6.8e-07 29.6 0.3 0.089 13.1 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EJP70919.1 - 5.8e-05 22.8 4.0 0.12 11.9 0.0 3.5 4 0 0 4 4 4 2 AAA domain ABC_ATPase PF09818.9 EJP70919.1 - 7e-05 21.8 0.5 0.0037 16.1 0.0 3.3 4 0 0 4 4 4 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 EJP70919.1 - 0.00017 20.9 0.3 0.024 13.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 EJP70919.1 - 0.00022 21.0 0.2 0.39 10.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EJP70919.1 - 0.00042 20.9 0.1 0.47 11.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EJP70919.1 - 0.00091 19.4 0.6 2.9 8.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EJP70919.1 - 0.0011 19.0 0.1 1.7 8.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EJP70919.1 - 0.0026 18.3 0.7 2.1 8.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 EJP70919.1 - 0.0039 16.9 0.4 5.1 6.7 0.0 3.2 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 EJP70919.1 - 0.0084 15.8 0.1 2.3 7.9 0.0 2.9 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EJP70919.1 - 0.0092 16.4 0.1 6.9 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EJP70919.1 - 0.011 16.1 0.2 17 5.9 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EJP70919.1 - 0.014 15.5 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EJP70919.1 - 0.031 13.5 0.7 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Ploopntkinase3 PF18751.1 EJP70919.1 - 0.032 14.2 0.7 2.1 8.3 0.0 2.9 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 EJP70919.1 - 0.035 14.0 0.1 3.8 7.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain APS_kinase PF01583.20 EJP70919.1 - 0.06 13.2 0.7 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase SbcCD_C PF13558.6 EJP70919.1 - 0.076 13.3 0.1 37 4.6 0.2 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EJP70919.1 - 0.077 12.5 0.2 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EJP70919.1 - 0.12 12.1 0.1 19 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EJP70919.1 - 0.3 11.3 1.7 1 9.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain Polysacc_synt_4 PF04669.13 EJP70920.1 - 2.5e-23 82.6 0.6 1e-21 77.4 0.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis MFS_1 PF07690.16 EJP70921.1 - 8.7e-31 107.1 20.7 8.7e-31 107.1 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1769 PF08588.10 EJP70922.1 - 3.5e-28 97.6 0.3 7.8e-28 96.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Ub-Mut7C PF14451.6 EJP70922.1 - 0.042 13.7 0.6 0.081 12.8 0.1 1.8 2 0 0 2 2 2 0 Mut7-C ubiquitin Cupin_2 PF07883.11 EJP70924.1 - 3.9e-11 42.5 0.1 6.3e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EJP70924.1 - 0.0075 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EJP70924.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 EJP70924.1 - 0.028 14.2 0.1 0.047 13.4 0.0 1.4 1 1 0 1 1 1 0 Cupin ARD PF03079.14 EJP70924.1 - 0.061 13.5 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family Cupin_3 PF05899.12 EJP70924.1 - 0.094 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF3506 PF12014.8 EJP70925.1 - 1e-51 174.6 0.0 2.3e-51 173.5 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 EJP70925.1 - 1.8e-05 24.5 2.0 1.8e-05 24.5 2.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EJP70925.1 - 0.0018 18.1 0.1 0.0052 16.6 0.1 1.9 1 1 0 1 1 1 1 F-box domain CTP_transf_like PF01467.26 EJP70926.1 - 0.016 15.4 0.1 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Cytidylyltransferase-like AHSA1 PF08327.11 EJP70927.1 - 5.3e-08 33.1 0.0 1.2e-07 32.0 0.0 1.6 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein RTA1 PF04479.13 EJP70928.1 - 0.11 12.1 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 RTA1 like protein Oxidored_molyb PF00174.19 EJP70929.1 - 3.6e-57 192.7 0.0 5.2e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EJP70929.1 - 1.3e-26 93.2 1.3 1.1e-15 57.8 0.1 3.2 3 1 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EJP70929.1 - 2.7e-13 49.9 0.1 5.9e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RPN2_C PF18004.1 EJP70930.1 - 1.1e-58 197.7 3.6 1.1e-58 197.7 3.6 1.6 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EJP70930.1 - 2.5e-40 134.9 15.7 1.1e-08 35.0 0.0 8.3 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EJP70930.1 - 2.1e-22 79.3 0.0 3.7e-14 52.9 0.0 5.4 3 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 EJP70930.1 - 8.6e-06 25.6 0.1 3.3 8.2 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 EJP70930.1 - 1.4e-05 25.5 0.3 0.019 15.4 0.0 5.0 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 EJP70930.1 - 0.0057 16.7 0.2 3 7.9 0.0 3.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 mRNA_triPase PF02940.15 EJP70931.1 - 9.1e-55 185.8 0.0 1.2e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Xan_ur_permease PF00860.20 EJP70932.1 - 9.2e-63 212.2 31.3 4.7e-61 206.6 31.3 2.1 1 1 0 1 1 1 1 Permease family BatD PF13584.6 EJP70933.1 - 0.0011 17.9 0.4 0.0012 17.8 0.4 1.0 1 0 0 1 1 1 1 Oxygen tolerance Trp_oprn_chp PF09534.10 EJP70933.1 - 0.0047 16.7 0.9 0.0058 16.5 0.9 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_holin_2_4 PF16082.5 EJP70933.1 - 0.0069 16.1 0.4 0.014 15.1 0.4 1.6 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like Consortin_C PF15281.6 EJP70933.1 - 0.018 15.0 0.7 0.031 14.3 0.6 1.6 1 1 0 1 1 1 0 Consortin C-terminus DUF4381 PF14316.6 EJP70933.1 - 0.021 15.1 0.5 0.021 15.1 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) STAC2_u1 PF16664.5 EJP70933.1 - 0.03 14.8 2.1 0.03 14.8 2.1 1.5 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF4834 PF16118.5 EJP70933.1 - 0.039 14.9 1.3 5.6 8.0 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Alpha_GJ PF03229.13 EJP70933.1 - 0.052 14.1 3.8 0.098 13.2 3.8 1.4 1 1 0 1 1 1 0 Alphavirus glycoprotein J Roughex PF06020.11 EJP70933.1 - 0.063 12.4 1.3 0.085 11.9 1.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2062 PF09835.9 EJP70933.1 - 0.13 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) EphA2_TM PF14575.6 EJP70933.1 - 0.15 13.0 0.7 2.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Annexin PF00191.20 EJP70935.1 - 5.4e-70 231.4 2.4 8.7e-19 67.4 0.0 4.4 4 1 0 4 4 4 4 Annexin DUF3574 PF12098.8 EJP70935.1 - 7.5e-05 22.5 0.1 0.37 10.6 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF3574) Acetyltransf_11 PF13720.6 EJP70935.1 - 0.055 13.9 2.3 9.3 6.8 0.0 3.6 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Minor_tail_Z PF06763.11 EJP70935.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) zf-C2H2_4 PF13894.6 EJP70937.1 - 0.032 15.1 4.1 1.2 10.2 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EJP70937.1 - 0.21 12.1 4.1 3.3 8.3 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type MSP1_C PF07462.11 EJP70937.1 - 5.3 5.6 5.1 9.3 4.8 5.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NOA36 PF06524.12 EJP70937.1 - 5.7 6.2 7.5 13 5.0 6.6 2.0 2 0 0 2 2 2 0 NOA36 protein SpoIIIAH PF12685.7 EJP70938.1 - 0.023 14.5 0.2 0.023 14.5 0.2 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein BTB PF00651.31 EJP70938.1 - 0.19 11.9 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain NOA36 PF06524.12 EJP70938.1 - 0.66 9.2 16.6 0.11 11.9 13.0 1.5 2 0 0 2 2 2 0 NOA36 protein Pox_Ag35 PF03286.14 EJP70938.1 - 0.95 9.2 10.2 0.14 11.9 2.4 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 EJP70938.1 - 1.5 9.0 16.8 0.076 13.3 10.2 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Ppx-GppA PF02541.16 EJP70940.1 - 2.9e-22 79.4 0.0 2.3e-21 76.5 0.0 2.2 2 1 0 2 2 2 1 Ppx/GppA phosphatase family Zn_clus PF00172.18 EJP70941.1 - 0.12 12.6 5.9 0.23 11.6 5.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.7 EJP70945.1 - 4.4e-05 23.7 0.4 0.42 11.1 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EJP70945.1 - 0.018 14.8 5.6 0.28 11.0 0.8 3.1 2 1 0 2 2 2 0 Leucine rich repeat F-box-like PF12937.7 EJP70945.1 - 0.15 12.0 5.9 0.084 12.8 2.7 2.4 2 1 0 2 2 2 0 F-box-like AICARFT_IMPCHas PF01808.18 EJP70946.1 - 3.1e-90 302.6 0.0 4.2e-90 302.2 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EJP70946.1 - 1.9e-23 82.5 0.0 3.6e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain SNF2_N PF00176.23 EJP70947.1 - 7.9e-34 116.9 0.0 1e-31 110.0 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EJP70947.1 - 6.7e-07 29.6 0.2 1.5e-06 28.6 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJP70947.1 - 0.014 15.4 0.0 4.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pro_Al_protease PF02983.14 EJP70947.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Alpha-lytic protease prodomain HECT_2 PF09814.9 EJP70949.1 - 9.6e-98 327.5 0.2 1.1e-97 327.3 0.2 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RIF5_SNase_1 PF18187.1 EJP70949.1 - 0.095 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 TbRIF5 SNase domain 1 DNA_RNApol_7kD PF03604.13 EJP70949.1 - 0.19 11.4 1.9 0.4 10.4 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S27e PF01667.17 EJP70949.1 - 0.42 10.4 1.8 3 7.6 0.3 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 Questin_oxidase PF14027.6 EJP70950.1 - 5.9e-64 216.7 0.3 9.3e-64 216.1 0.3 1.3 1 0 0 1 1 1 1 Questin oxidase-like Rad17 PF03215.15 EJP70950.1 - 1.4e-27 96.8 0.0 2.7e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EJP70950.1 - 0.00038 20.9 0.0 0.0018 18.7 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EJP70950.1 - 0.003 16.7 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EJP70950.1 - 0.0035 17.8 0.0 0.012 16.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EJP70950.1 - 0.0064 17.0 0.0 0.04 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EJP70950.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EJP70950.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EJP70950.1 - 0.023 14.6 0.1 0.29 11.0 0.1 2.8 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EJP70950.1 - 0.028 14.6 0.0 0.086 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EJP70950.1 - 0.035 14.4 0.2 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3885 PF13021.6 EJP70950.1 - 0.036 14.2 0.5 0.13 12.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) AAA_19 PF13245.6 EJP70950.1 - 0.054 13.8 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 EJP70950.1 - 0.056 13.7 0.1 8.1 6.7 0.0 3.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Viral_helicase1 PF01443.18 EJP70950.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EJP70950.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EJP70950.1 - 0.12 12.4 0.1 0.92 9.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Herpes_Helicase PF02689.14 EJP70950.1 - 0.15 9.9 0.0 0.34 8.8 0.0 1.5 2 0 0 2 2 2 0 Helicase Lipase_GDSL_2 PF13472.6 EJP70952.1 - 1.5e-18 67.8 0.0 1.8e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EJP70952.1 - 6.4e-08 32.8 0.0 1.3e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PCI PF01399.27 EJP70953.1 - 2.8e-11 43.9 0.0 9.3e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 EJP70953.1 - 0.0055 16.4 0.6 0.033 13.9 0.0 2.4 2 1 1 3 3 3 1 26S proteasome subunit RPN7 Pex14_N PF04695.13 EJP70954.1 - 0.68 10.6 11.7 0.81 10.3 11.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim17 PF02466.19 EJP70955.1 - 4.7e-12 46.3 0.5 8.1e-12 45.5 0.3 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 EJP70955.1 - 0.031 14.4 1.2 2.5 8.3 0.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5518) BPD_transp_2 PF02653.16 EJP70955.1 - 0.07 12.3 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component DNA_pol_B_palm PF14792.6 EJP70956.1 - 8e-30 103.4 0.0 1.7e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EJP70956.1 - 4.8e-24 84.3 0.7 2.3e-23 82.2 0.4 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 EJP70956.1 - 6.7e-20 71.2 0.1 5e-19 68.4 0.2 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EJP70956.1 - 5.3e-16 58.2 0.0 1.3e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 EJP70956.1 - 0.001 19.6 0.0 0.13 12.8 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRX_N PF13713.6 EJP70957.1 - 0.017 14.9 0.1 0.059 13.1 0.1 2.0 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain APC_N_CC PF16689.5 EJP70957.1 - 0.039 14.0 3.1 1.3 9.2 0.3 4.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain GIT_CC PF16559.5 EJP70957.1 - 0.072 13.0 0.2 0.072 13.0 0.2 5.2 5 1 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor FIVAR PF07554.13 EJP70957.1 - 3.7 8.4 9.4 0.17 12.7 0.7 3.2 3 0 0 3 3 3 0 FIVAR domain Pox_A_type_inc PF04508.12 EJP70957.1 - 8.7 6.4 9.5 3 7.9 0.1 5.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Med16 PF11635.8 EJP70958.1 - 2.9e-82 276.8 0.0 3.6e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 PP2C PF00481.21 EJP70959.1 - 3.8e-36 125.0 0.0 5.8e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EJP70959.1 - 1.9e-07 30.9 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C VHP PF02209.19 EJP70960.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Villin headpiece domain Sortilin-Vps10 PF15902.5 EJP70962.1 - 4.6e-290 961.7 17.0 2.4e-145 484.8 1.1 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EJP70962.1 - 4e-89 297.4 30.7 2.2e-45 155.1 10.9 2.7 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EJP70962.1 - 3.4e-07 29.3 46.3 0.65 10.2 0.1 12.4 12 0 0 12 12 12 4 BNR/Asp-box repeat BNR_2 PF13088.6 EJP70962.1 - 1.8e-06 27.5 11.0 0.17 11.1 1.1 6.7 5 3 2 7 7 7 3 BNR repeat-like domain CHB_HEX_C PF03174.13 EJP70962.1 - 0.0029 17.6 1.0 1 9.4 0.1 5.0 5 0 0 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF2561 PF10812.8 EJP70962.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) PSII_BNR PF14870.6 EJP70962.1 - 0.052 12.8 6.4 6.4 5.9 0.0 5.0 4 2 1 5 5 5 0 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 EJP70962.1 - 0.52 10.5 0.0 0.52 10.5 0.0 5.4 7 0 0 7 7 7 0 BNR-Asp box repeat F5_F8_type_C PF00754.25 EJP70962.1 - 1.3 9.2 15.5 5.1 7.2 0.1 6.7 7 1 1 8 8 8 0 F5/8 type C domain AA_permease PF00324.21 EJP70964.1 - 1.4e-138 462.5 33.1 1.7e-138 462.2 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJP70964.1 - 3.3e-35 121.8 35.6 4e-35 121.5 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_47 PF01532.20 EJP70965.1 - 5.1e-171 569.6 0.1 6.1e-171 569.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Autophagy_act_C PF03987.15 EJP70966.1 - 3.1e-14 53.3 0.3 5.5e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 EJP70967.1 - 1.3e-08 34.5 0.0 3.4e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJP70967.1 - 5.1e-05 22.9 0.0 8.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 EJP70967.1 - 0.00025 20.8 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.8 EJP70967.1 - 0.007 16.4 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 CCDC71L PF15374.6 EJP70967.1 - 0.017 14.4 0.1 0.023 14.0 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L SET_assoc PF11767.8 EJP70967.1 - 0.054 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 EJP70967.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ceramidase PF05875.12 EJP70968.1 - 2.4e-60 204.2 3.8 2.7e-60 204.0 3.8 1.0 1 0 0 1 1 1 1 Ceramidase PAS_9 PF13426.7 EJP70969.1 - 2.3e-14 53.5 0.0 3e-13 49.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EJP70969.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold AhpC-TSA PF00578.21 EJP70971.1 - 4.4e-31 107.4 0.0 5.6e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJP70971.1 - 1.2e-14 54.3 0.0 1.5e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EJP70971.1 - 2.6e-13 49.6 0.1 4.8e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_4 PF13418.6 EJP70972.1 - 3.1e-17 62.3 0.7 6e-07 29.4 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EJP70972.1 - 6.5e-16 58.0 0.9 2.7e-06 27.4 0.1 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 EJP70972.1 - 2.7e-15 56.0 1.6 1.1e-06 28.5 0.1 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 EJP70972.1 - 2.9e-14 52.9 10.6 5.4e-09 36.1 0.0 6.7 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EJP70972.1 - 3.5e-14 52.1 0.1 0.00013 21.4 0.0 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EJP70972.1 - 3.5e-09 36.3 1.7 0.00015 21.6 0.0 4.7 4 1 0 4 4 4 2 Kelch motif BTB PF00651.31 EJP70972.1 - 0.044 14.0 0.0 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 BTB/POZ domain AMP-binding PF00501.28 EJP70973.1 - 1.9e-63 214.5 0.0 3e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP70973.1 - 8.9e-07 29.8 0.2 2.3e-06 28.5 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIG-S PF10510.9 EJP70974.1 - 4.6e-160 533.9 0.0 5.5e-160 533.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Peptidase_S9 PF00326.21 EJP70976.1 - 0.00014 21.5 0.2 0.0006 19.3 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EJP70976.1 - 0.0017 17.7 0.1 1.5 8.0 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EJP70976.1 - 0.0036 16.9 0.0 0.0081 15.8 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Mucin PF01456.17 EJP70976.1 - 0.024 14.6 0.8 0.044 13.8 0.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.11 EJP70976.1 - 0.33 10.9 4.0 1.2 9.0 2.2 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Aldedh PF00171.22 EJP70977.1 - 3.3e-184 612.7 1.5 3.8e-184 612.5 1.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EJP70977.1 - 0.0021 17.5 0.0 0.12 11.8 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1487) AA_permease_2 PF13520.6 EJP70978.1 - 5.4e-57 193.5 42.8 6.8e-57 193.2 42.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJP70978.1 - 5e-20 71.6 33.2 7.1e-20 71.1 33.2 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 EJP70979.1 - 8.5e-155 515.7 0.0 1e-154 515.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EJP70979.1 - 1.2e-19 70.6 0.0 3.2e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EJP70979.1 - 1.7e-14 53.8 0.0 2.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Myb_DNA-bind_6 PF13921.6 EJP70980.1 - 0.0015 18.7 0.6 0.011 16.0 0.3 2.5 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EJP70980.1 - 0.0058 16.8 1.3 0.0086 16.2 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain UbiA PF01040.18 EJP70981.1 - 1.1e-60 205.1 13.6 1.1e-60 205.1 13.6 1.8 2 1 0 2 2 2 1 UbiA prenyltransferase family DUF3336 PF11815.8 EJP70981.1 - 1.3e-33 115.6 0.1 2.8e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EJP70981.1 - 3.8e-22 79.5 0.0 1.6e-21 77.5 0.0 2.1 1 0 0 1 1 1 1 Patatin-like phospholipase Spt20 PF12090.8 EJP70981.1 - 0.48 10.0 28.9 1.1 8.8 20.3 2.3 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 EJP70981.1 - 0.63 10.0 25.9 0.49 10.3 14.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 EJP70981.1 - 1.3 8.4 5.1 2.7 7.3 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SUIM_assoc PF16619.5 EJP70981.1 - 2.8 8.1 27.6 2.3 8.4 15.3 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 EJP70982.1 - 1.1e-48 166.0 0.0 2.9e-48 164.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJP70982.1 - 8e-19 67.9 0.0 3.6e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJP70982.1 - 0.0043 16.4 0.1 0.009 15.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJP70982.1 - 0.015 14.6 0.9 1.1 8.5 0.1 2.3 1 1 0 2 2 2 0 Kinase-like RIO1 PF01163.22 EJP70982.1 - 0.039 13.5 0.0 0.098 12.2 0.0 1.6 1 1 0 1 1 1 0 RIO1 family Njmu-R1 PF15053.6 EJP70983.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Mjmu-R1-like protein family Fasciclin PF02469.22 EJP70984.1 - 5.9e-42 142.9 0.0 3.3e-20 72.6 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain APH PF01636.23 EJP70985.1 - 3.5e-16 59.9 0.0 6.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJP70985.1 - 8.4e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Glyco_hydro_35 PF01301.19 EJP70986.1 - 1e-91 307.9 0.2 1.3e-91 307.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EJP70986.1 - 4.2e-09 36.2 0.3 6.7e-09 35.6 0.3 1.4 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 EJP70986.1 - 1e-07 32.5 0.1 0.00011 22.7 0.0 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain Ank_2 PF12796.7 EJP70987.1 - 1.2e-25 89.9 0.0 1.3e-11 44.9 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EJP70987.1 - 3e-23 81.2 0.5 3.6e-06 27.2 0.0 5.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EJP70987.1 - 4.9e-22 78.0 0.2 1.9e-14 53.8 0.0 3.9 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP70987.1 - 1.5e-17 61.9 0.1 4.6e-05 23.5 0.0 5.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EJP70987.1 - 1.5e-15 57.0 0.1 2.5e-07 30.9 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) NACHT PF05729.12 EJP70987.1 - 6.9e-11 42.4 0.0 2.1e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 EJP70987.1 - 0.0049 16.9 0.0 3.8 7.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF5535 PF17687.1 EJP70987.1 - 0.027 14.6 0.2 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5535) KAP_NTPase PF07693.14 EJP70987.1 - 0.031 13.5 0.1 0.091 12.0 0.1 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.6 EJP70987.1 - 0.036 14.4 0.1 0.19 12.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EJP70987.1 - 0.057 13.8 0.0 0.21 12.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Peptidase_C65 PF10275.9 EJP70987.1 - 0.22 11.0 0.6 0.56 9.6 0.1 1.8 2 0 0 2 2 2 0 Peptidase C65 Otubain HlyIII PF03006.20 EJP70988.1 - 5.8e-47 160.3 20.1 7.5e-47 159.9 20.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_S8 PF00082.22 EJP70989.1 - 1.2e-18 67.4 0.1 2.1e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 EJP70991.1 - 3.7e-58 194.1 5.0 9.1e-15 55.0 0.1 6.6 2 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJP70991.1 - 4.7e-49 164.2 11.5 2.1e-08 34.5 0.0 8.9 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJP70991.1 - 6.1e-41 133.7 7.6 0.00057 20.1 0.0 12.6 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 EJP70991.1 - 1.2e-38 130.6 15.6 3.3e-06 27.3 0.0 9.9 4 2 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 EJP70991.1 - 2.2e-29 100.6 21.0 0.00058 20.2 0.0 11.3 11 0 0 11 11 11 6 Ankyrin repeat Toxin_trans PF07952.12 EJP70993.1 - 0.00086 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain DUF4890 PF16231.5 EJP70993.1 - 1.7 9.1 5.5 1.8 9.1 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) SesA PF17107.5 EJP70994.1 - 0.027 14.6 0.1 0.032 14.4 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4229 PF14012.6 EJP70994.1 - 0.19 11.8 1.9 0.17 12.0 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Melibiase_2 PF16499.5 EJP70995.1 - 1.2e-51 175.6 0.6 2e-51 174.9 0.6 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EJP70995.1 - 4.8e-14 52.2 0.4 3.2e-13 49.5 0.0 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Ricin_B_lectin PF00652.22 EJP70995.1 - 7.5e-10 39.1 1.8 1.3e-09 38.4 1.8 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase PF02065.18 EJP70995.1 - 0.0043 16.1 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Melibiase Amidohydro_2 PF04909.14 EJP70996.1 - 1.5e-36 126.7 1.0 2e-36 126.3 1.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 EJP70997.1 - 2.9e-09 36.3 0.1 5.9e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJP70997.1 - 3.3e-05 23.9 7.6 6.9e-05 22.9 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 EJP70998.1 - 1e-14 54.6 2.2 1.2e-13 51.1 2.2 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EJP70998.1 - 1.4e-08 34.8 0.7 3.8e-08 33.4 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJP70998.1 - 3.3e-05 23.3 0.1 5.6e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJP70998.1 - 0.00027 20.2 2.4 0.0017 17.5 1.2 2.0 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 EJP70998.1 - 0.00033 20.3 4.7 0.00066 19.4 4.7 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJP70998.1 - 0.0015 19.1 1.0 0.0045 17.5 1.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EJP70998.1 - 0.0019 17.6 0.1 0.0029 17.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rossmann-like PF10727.9 EJP70998.1 - 0.0088 15.9 0.2 0.02 14.7 0.2 1.6 1 0 0 1 1 1 1 Rossmann-like domain GIDA PF01134.22 EJP70998.1 - 0.024 13.7 2.1 0.047 12.8 2.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EJP70998.1 - 0.13 11.5 0.6 0.72 9.0 1.7 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJP70998.1 - 0.33 9.6 1.3 0.51 9.0 1.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Dioxygenase_C PF00775.21 EJP70999.1 - 1.1e-49 168.4 0.0 1.6e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EJP70999.1 - 9.8e-28 95.8 0.1 1.6e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EJP70999.1 - 1.5e-06 28.4 0.0 1.8e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EJP70999.1 - 0.0092 16.3 0.1 0.13 12.6 0.0 2.2 2 0 0 2 2 2 1 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 EJP70999.1 - 0.013 15.4 0.0 1.8 8.6 0.0 3.3 4 0 0 4 4 4 0 CarboxypepD_reg-like domain DUF4198 PF10670.9 EJP70999.1 - 0.014 15.8 0.0 0.042 14.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) SdrD_B PF17210.3 EJP70999.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 SdrD B-like domain CoA_transf_3 PF02515.17 EJP71000.1 - 3.4e-43 148.2 0.2 9.4e-40 136.8 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Metal_resist PF13801.6 EJP71000.1 - 0.063 13.5 0.1 0.2 11.9 0.1 1.8 1 0 0 1 1 1 0 Heavy-metal resistance Dala_Dala_lig_C PF07478.13 EJP71001.1 - 4.5e-25 88.4 0.0 6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EJP71001.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EJP71001.1 - 0.025 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Sgf11_N PF18519.1 EJP71001.1 - 1.2 8.7 3.3 27 4.4 3.3 2.4 1 1 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain AMP-binding PF00501.28 EJP71002.1 - 5e-75 252.7 0.0 6.3e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJP71002.1 - 7e-16 59.0 2.0 2.6e-15 57.1 0.2 2.8 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Goodbye PF17109.5 EJP71003.1 - 1.8e-33 115.6 2.7 2.4e-33 115.1 0.3 2.6 3 0 0 3 3 2 1 fungal STAND N-terminal Goodbye domain TPR_1 PF00515.28 EJP71003.1 - 7.8e-12 44.5 6.2 1.7e-05 24.4 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJP71003.1 - 4.9e-11 42.7 7.5 2e-05 24.8 0.1 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJP71003.1 - 8.6e-11 41.1 10.0 0.00012 21.9 0.0 4.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJP71003.1 - 1.7e-09 37.1 6.9 0.00075 19.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 EJP71003.1 - 4.7e-06 27.1 0.1 5.5e-05 23.6 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain TPR_11 PF13414.6 EJP71003.1 - 0.00012 21.7 1.9 0.0049 16.5 0.0 3.0 2 0 0 2 2 2 1 TPR repeat NACHT PF05729.12 EJP71003.1 - 0.00037 20.4 0.0 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TPR_10 PF13374.6 EJP71003.1 - 0.00083 19.2 6.1 0.47 10.4 0.1 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.6 EJP71003.1 - 0.0023 18.2 0.0 0.021 15.1 0.0 2.6 2 1 1 3 3 3 1 AAA domain TPR_6 PF13174.6 EJP71003.1 - 0.0064 17.1 0.8 1.2 9.9 0.2 3.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJP71003.1 - 0.0073 16.9 0.8 0.93 10.2 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat GTA_TIM PF13547.6 EJP71003.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 GTA TIM-barrel-like domain IstB_IS21 PF01695.17 EJP71003.1 - 0.011 15.5 0.1 0.064 13.0 0.0 2.3 3 0 0 3 3 2 0 IstB-like ATP binding protein TPR_19 PF14559.6 EJP71003.1 - 0.017 15.6 3.9 0.024 15.1 0.6 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF2075 PF09848.9 EJP71003.1 - 0.019 14.2 0.0 0.043 13.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_14 PF13428.6 EJP71003.1 - 0.024 15.4 6.8 0.22 12.4 0.0 4.9 4 1 0 4 4 3 0 Tetratricopeptide repeat AAA_33 PF13671.6 EJP71003.1 - 0.028 14.6 0.0 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain TPR_7 PF13176.6 EJP71003.1 - 0.038 14.0 12.0 0.05 13.6 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat RNA_helicase PF00910.22 EJP71003.1 - 0.11 12.9 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase ANAPC3 PF12895.7 EJP71003.1 - 0.53 10.5 7.8 5 7.4 1.5 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DJ-1_PfpI PF01965.24 EJP71004.1 - 4.6e-18 65.6 0.0 5.6e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family LIP PF03583.14 EJP71005.1 - 3.1e-79 266.3 0.1 5.1e-79 265.6 0.1 1.3 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EJP71005.1 - 0.0044 16.5 0.1 0.032 13.7 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family MFS_1 PF07690.16 EJP71006.1 - 2.5e-11 43.1 50.6 3.8e-10 39.2 49.5 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily EHN PF06441.12 EJP71007.1 - 2.5e-35 121.1 0.1 3.9e-34 117.3 0.0 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EJP71007.1 - 4.3e-13 49.5 0.1 1.8e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJP71007.1 - 1.3e-06 29.2 2.6 1.3e-06 29.2 2.6 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Mito_carr PF00153.27 EJP71008.1 - 6e-53 176.8 2.8 1.2e-22 79.6 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Phage_tail_NK PF16532.5 EJP71008.1 - 0.084 12.5 0.2 13 5.4 0.0 3.0 2 1 1 3 3 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales DUF2370 PF10176.9 EJP71010.1 - 9.5e-90 300.2 1.0 2.1e-89 299.0 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2370) SLATT_fungal PF18142.1 EJP71011.1 - 3.8e-34 117.3 0.3 5.4e-34 116.8 0.3 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain PCMT PF01135.19 EJP71012.1 - 8.1e-56 189.1 0.0 1.1e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EJP71012.1 - 2.9e-05 23.9 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EJP71012.1 - 0.00093 19.2 0.0 0.0045 17.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJP71012.1 - 0.0064 17.2 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJP71012.1 - 0.0091 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.19 EJP71012.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Ubie_methyltran PF01209.18 EJP71012.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EJP71012.1 - 0.029 15.0 0.0 0.042 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.13 EJP71015.1 - 6.5e-15 55.3 0.0 8.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EJP71015.1 - 3.6e-12 46.6 0.2 1e-11 45.1 0.2 1.8 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EJP71015.1 - 0.079 12.4 0.2 0.37 10.2 0.0 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family HSBP1 PF06825.12 EJP71017.1 - 0.067 13.1 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CN_hydrolase PF00795.22 EJP71018.1 - 9.8e-48 162.7 0.0 1.1e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Nmad3 PF18754.1 EJP71018.1 - 0.2 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 APH PF01636.23 EJP71019.1 - 0.00032 20.7 0.0 0.0012 18.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EJP71019.1 - 0.00035 20.0 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Fer4 PF00037.27 EJP71020.1 - 1.7e-13 49.8 16.5 6.2e-08 32.1 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EJP71020.1 - 9.9e-13 48.5 10.2 1.6e-12 47.8 10.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EJP71020.1 - 2.7e-10 41.0 7.4 8.1e-05 23.5 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EJP71020.1 - 2.3e-09 37.3 31.7 6.9e-06 26.1 12.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 EJP71020.1 - 1.3e-08 34.8 21.0 2.6e-06 27.5 12.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EJP71020.1 - 4.1e-08 33.3 9.9 9e-08 32.2 10.0 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EJP71020.1 - 4e-07 30.4 18.9 0.00011 22.6 10.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EJP71020.1 - 1.6e-06 27.9 17.1 0.0004 20.3 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EJP71020.1 - 5e-06 26.3 11.8 0.0099 15.9 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EJP71020.1 - 9.3e-06 25.8 11.4 0.0003 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EJP71020.1 - 0.00041 20.8 12.0 0.067 13.8 13.0 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EJP71020.1 - 0.0058 16.8 5.4 0.59 10.4 0.4 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain ETF_QO PF05187.13 EJP71020.1 - 0.046 13.8 5.2 0.2 11.8 0.4 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 EJP71020.1 - 0.07 13.3 8.8 1.2 9.3 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EJP71020.1 - 0.076 13.6 15.2 0.75 10.4 4.3 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 EJP71020.1 - 0.25 12.4 15.5 0.43 11.6 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EJP71020.1 - 0.62 10.9 11.8 3.6 8.5 1.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Peptidase_M14 PF00246.24 EJP71021.1 - 3.3e-36 125.6 0.0 4.7e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase PP-binding PF00550.25 EJP71022.1 - 3.9e-12 46.4 0.1 5e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EJP71022.1 - 7.2e-05 22.9 0.2 9.8e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.24 EJP71023.1 - 9.8e-11 41.3 7.9 3.2e-05 23.7 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EJP71023.1 - 3.7e-10 39.4 10.7 1.4e-05 24.7 3.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EJP71023.1 - 4.8e-10 39.2 17.5 7.9e-05 22.6 4.4 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EJP71023.1 - 9.2e-09 36.0 5.3 0.00011 22.8 0.5 2.6 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EJP71023.1 - 4.6e-06 26.8 1.8 9.7e-06 25.8 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EJP71023.1 - 0.073 13.6 17.4 0.71 10.4 6.4 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Amidohydro_1 PF01979.20 EJP71025.1 - 7.9e-30 104.3 0.1 7e-29 101.2 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EJP71025.1 - 2.9e-13 50.1 0.0 1.2e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family bZIP_2 PF07716.15 EJP71026.1 - 1.4e-07 31.5 5.1 2.3e-07 30.8 5.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EJP71026.1 - 4.5e-05 23.5 5.3 6.4e-05 23.0 5.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EJP71026.1 - 0.001 19.5 6.0 0.0014 19.1 6.0 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Hamartin PF04388.12 EJP71026.1 - 0.028 13.1 0.9 0.031 13.0 0.9 1.0 1 0 0 1 1 1 0 Hamartin protein Pox_A_type_inc PF04508.12 EJP71026.1 - 0.11 12.3 1.0 0.29 11.0 0.3 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Transp_cyt_pur PF02133.15 EJP71027.1 - 1.8e-30 106.1 32.2 6.8e-30 104.2 32.2 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Helicase_C_2 PF13307.6 EJP71028.1 - 3.7e-61 206.3 0.0 9e-61 205.0 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EJP71028.1 - 4.5e-48 163.2 0.0 7.7e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EJP71028.1 - 0.0043 17.1 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EJP71028.1 - 0.078 12.7 0.1 0.56 10.0 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase Ribosomal_L27A PF00828.19 EJP71029.1 - 8.5e-21 75.0 0.0 1.1e-20 74.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 EJP71030.1 - 1.2e-41 142.9 0.0 6.6e-39 133.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJP71030.1 - 7.7e-15 54.9 0.0 1.9e-09 37.2 0.0 3.6 3 1 1 4 4 4 2 Protein tyrosine kinase APH PF01636.23 EJP71030.1 - 0.0015 18.5 0.3 0.16 11.9 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EJP71030.1 - 0.0019 17.0 0.0 0.0037 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EJP71030.1 - 0.064 12.9 0.0 0.79 9.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EJP71030.1 - 0.11 11.8 0.0 12 5.1 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Cnd1_N PF12922.7 EJP71031.1 - 5e-63 211.9 0.8 5.7e-62 208.5 0.5 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EJP71031.1 - 1.7e-48 164.7 7.0 2.1e-44 151.4 0.2 3.9 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJP71031.1 - 4e-10 40.0 0.9 0.00016 22.0 0.1 4.7 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EJP71031.1 - 1.1e-09 37.7 6.1 0.022 15.0 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 EJP71031.1 - 6.6e-06 26.3 0.1 0.068 13.4 0.0 3.6 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EJP71031.1 - 1.6e-05 25.3 4.3 0.026 15.0 0.1 5.0 4 0 0 4 4 4 1 HEAT-like repeat Cnd3 PF12719.7 EJP71031.1 - 0.0011 18.2 9.6 0.0023 17.2 0.4 4.1 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain MIEAP PF16026.5 EJP71031.1 - 0.037 14.2 2.5 0.052 13.8 0.2 2.5 3 0 0 3 3 3 0 Mitochondria-eating protein Ald_Xan_dh_C2 PF02738.18 EJP71031.1 - 0.091 11.2 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase NIF PF03031.18 EJP71032.1 - 2.7e-27 95.5 0.0 8e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EJP71032.1 - 1.5e-08 34.9 0.0 1.2e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EJP71032.1 - 0.00019 21.3 0.1 0.00077 19.4 0.0 2.1 2 1 1 3 3 3 1 twin BRCT domain BRCT_2 PF16589.5 EJP71032.1 - 0.00071 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EJP71032.1 - 0.0075 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EJP71032.1 - 0.017 15.2 1.6 0.021 14.9 0.3 1.8 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.22 EJP71032.1 - 0.042 13.7 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme Beta-lactamase PF00144.24 EJP71033.1 - 7.5e-47 160.2 0.0 3.9e-46 157.8 0.0 1.8 1 1 1 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 EJP71033.1 - 3.6e-09 37.0 0.0 5.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) adh_short PF00106.25 EJP71034.1 - 1e-19 70.8 0.0 7.9e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EJP71034.1 - 5.5e-13 49.0 0.1 2.7e-08 33.6 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJP71034.1 - 6.9e-09 35.9 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EJP71034.1 - 0.028 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EJP71034.1 - 0.048 13.1 0.0 0.072 12.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GRIM-19 PF06212.12 EJP71035.1 - 1e-24 86.9 0.1 3.4e-24 85.3 0.1 1.7 1 1 0 1 1 1 1 GRIM-19 protein GRAM PF02893.20 EJP71037.1 - 7.7e-33 112.8 3.3 3.8e-20 71.9 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 EJP71037.1 - 4e-28 98.2 0.0 7.5e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 EJP71037.1 - 7.8e-14 52.1 0.0 2.6e-13 50.4 0.0 2.0 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 EJP71037.1 - 2e-06 26.9 0.0 3.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 EJP71037.1 - 6.4e-05 23.3 1.2 0.00086 19.7 1.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EJP71037.1 - 6.8e-05 23.1 0.1 0.00015 22.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EJP71037.1 - 0.0061 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 EJP71037.1 - 0.071 13.5 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_6 PF15406.6 EJP71037.1 - 0.097 13.0 0.3 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Acetyltransf_10 PF13673.7 EJP71038.1 - 2.9e-13 49.8 0.0 3.9e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJP71038.1 - 3.5e-13 49.8 0.1 4.3e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJP71038.1 - 3.6e-12 46.5 0.1 5.7e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJP71038.1 - 5.6e-05 23.3 0.1 7.8e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJP71038.1 - 0.0041 17.1 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EJP71038.1 - 0.0055 16.8 0.0 0.0074 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40 PF00400.32 EJP71039.1 - 6.2e-08 33.2 10.7 0.14 13.1 0.0 4.9 4 1 0 4 4 4 4 WD domain, G-beta repeat PLAC8 PF04749.17 EJP71041.1 - 1.6e-22 80.3 14.0 2.1e-22 80.0 14.0 1.1 1 0 0 1 1 1 1 PLAC8 family GST_N_3 PF13417.6 EJP71042.1 - 1.4e-07 31.8 0.0 3.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJP71042.1 - 1.3e-06 28.6 0.1 3.3e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJP71042.1 - 0.0016 18.4 0.1 0.0028 17.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJP71042.1 - 0.022 14.9 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Beta-lactamase PF00144.24 EJP71043.1 - 1.3e-31 110.1 0.0 1.7e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 EJP71044.1 - 1.5e-26 93.2 51.2 1.6e-19 70.0 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJP71045.1 - 5.6e-129 430.9 32.1 6.5e-129 430.7 32.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJP71045.1 - 2.1e-24 86.1 38.9 3e-16 59.3 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OmpA_like PF16961.5 EJP71045.1 - 0.008 15.9 0.4 0.35 10.5 0.0 2.2 2 0 0 2 2 2 1 Putative OmpA-OmpF-like porin family Glyco_transf_20 PF00982.21 EJP71046.1 - 1.1e-145 485.9 0.0 1.6e-145 485.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EJP71046.1 - 7.2e-68 228.2 0.0 1.2e-67 227.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Zn_clus PF00172.18 EJP71047.1 - 6.3e-09 35.8 10.6 9.9e-09 35.2 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EJP71047.1 - 0.0044 16.1 0.2 0.024 13.7 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain UPF0688 PF15772.5 EJP71047.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 UPF0688 family zf-C2H2 PF00096.26 EJP71048.1 - 0.03 14.8 3.9 0.36 11.4 3.9 2.6 1 1 0 1 1 1 0 Zinc finger, C2H2 type DUF2434 PF10361.9 EJP71049.1 - 5.9e-135 448.9 10.6 7.5e-135 448.6 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Neur_chan_memb PF02932.16 EJP71049.1 - 0.19 11.8 0.1 0.61 10.1 0.0 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PHO4 PF01384.20 EJP71049.1 - 0.21 10.6 3.9 16 4.4 0.2 3.2 1 1 1 2 2 2 0 Phosphate transporter family COG5 PF10392.9 EJP71050.1 - 3.1e-35 121.2 9.6 5.3e-35 120.5 1.4 3.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 SRX PF09201.10 EJP71050.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit Uso1_p115_C PF04871.13 EJP71050.1 - 0.19 12.1 1.0 0.45 10.9 1.0 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Gelsolin PF00626.22 EJP71051.1 - 1.2e-35 121.2 0.1 4.4e-14 52.1 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Beauveria_bassiana_ARSEF_2860-ASM28067v1/GCA_000280675.1_ASM28067v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Beauveria_bassiana_ARSEF_2860-ASM28067v1/GCA_000280675.1_ASM28067v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Beauveria_bassiana_ARSEF_2860-ASM28067v1/GCA_000280675.1_ASM28067v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Beauveria_bassiana_ARSEF_2860-ASM28067v1/GCA_000280675.1_ASM28067v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 15:19:05 2019 # [ok]