# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RPN7 PF10602.9 EMC90818.1 - 3.8e-24 85.3 0.0 6e-12 45.6 0.0 2.6 2 1 0 2 2 2 2 26S proteasome subunit RPN7 PCI PF01399.27 EMC90818.1 - 8.3e-10 39.1 0.0 1.5e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF3716 PF12511.8 EMC90819.1 - 9.6e-09 35.2 7.7 1.8e-08 34.3 7.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Chromo PF00385.24 EMC90819.1 - 0.00013 21.8 0.3 0.084 12.8 0.0 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Neur_chan_memb PF02932.16 EMC90819.1 - 1.9 8.5 4.0 0.37 10.8 0.5 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-XS PF03470.14 EMC90820.1 - 0.02 15.1 0.2 0.02 15.1 0.2 2.9 4 0 0 4 4 4 0 XS zinc finger domain TMEM154 PF15102.6 EMC90822.1 - 1.1e-05 25.3 0.1 2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family RCR PF12273.8 EMC90822.1 - 0.00018 22.1 0.4 0.002 18.7 0.0 2.2 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.11 EMC90822.1 - 0.0056 16.6 1.0 0.011 15.7 1.0 1.5 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein DUF1180 PF06679.12 EMC90822.1 - 0.019 15.4 0.6 0.05 14.0 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4381 PF14316.6 EMC90822.1 - 0.026 14.8 0.3 0.058 13.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF443 PF04276.12 EMC90822.1 - 0.036 13.9 0.1 0.051 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) BatD PF13584.6 EMC90822.1 - 0.086 11.6 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4711 PF15829.5 EMC90822.1 - 0.19 11.7 0.5 0.33 10.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) CFEM PF05730.11 EMC90822.1 - 2.6 8.2 12.7 6.1 7.0 12.6 1.7 1 1 0 1 1 1 0 CFEM domain TIL PF01826.17 EMC90822.1 - 5.9 7.2 8.9 3.6 7.9 2.7 2.2 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain BTB PF00651.31 EMC90823.1 - 0.00012 22.3 0.0 0.00026 21.2 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain AhpC-TSA_2 PF13911.6 EMC90825.1 - 1.2e-18 67.3 0.0 1.7e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EMC90825.1 - 0.00077 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family NB-ARC PF00931.22 EMC90827.1 - 0.001 18.3 0.1 0.0016 17.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain BTB PF00651.31 EMC90829.1 - 1e-07 32.2 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HrpJ PF07201.11 EMC90830.1 - 0.016 15.6 1.4 0.026 14.8 1.4 1.3 1 0 0 1 1 1 0 HrpJ-like domain F-box-like_2 PF13013.6 EMC90830.1 - 0.091 12.7 0.3 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 F-box-like domain MFS_1 PF07690.16 EMC90831.1 - 6.7e-21 74.6 50.0 3.6e-20 72.2 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC90831.1 - 3.1e-16 59.3 25.7 7.7e-13 48.1 5.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter S1-P1_nuclease PF02265.16 EMC90833.1 - 4e-67 226.7 0.4 4.6e-67 226.5 0.4 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Abhydrolase_3 PF07859.13 EMC90834.1 - 1.7e-36 126.1 0.0 2.1e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EMC90834.1 - 4.1e-05 23.3 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 Putative esterase DLH PF01738.18 EMC90834.1 - 5.7e-05 22.8 0.0 0.00066 19.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family COesterase PF00135.28 EMC90834.1 - 0.00083 18.3 0.0 0.068 12.0 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 EMC90834.1 - 0.0054 16.2 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EMC90834.1 - 0.0063 16.1 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EMC90834.1 - 0.015 14.0 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 EMC90834.1 - 0.51 10.9 7.5 1 9.9 7.4 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3237 PF11578.8 EMC90835.1 - 6.1e-28 97.5 0.0 3.8e-26 91.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) PA_decarbox PF05870.11 EMC90836.1 - 3.6e-07 29.9 0.2 4.8e-07 29.5 0.2 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) PQ-loop PF04193.14 EMC90837.1 - 2.6e-36 123.2 5.3 6.2e-18 64.3 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Comm PF15957.5 EMC90837.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Commissureless ADH_N PF08240.12 EMC90839.1 - 1.1e-29 102.5 0.2 2.1e-29 101.6 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC90839.1 - 7.5e-21 74.5 0.1 1.1e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMC90839.1 - 2.2e-08 33.9 0.1 6.2e-08 32.4 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EMC90839.1 - 1.5e-06 27.7 0.3 2.6e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EMC90839.1 - 9.7e-06 26.7 0.0 1.9e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_10 PF13237.6 EMC90839.1 - 0.0069 16.5 1.7 0.25 11.5 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain ADH_N_assoc PF13823.6 EMC90839.1 - 1.9 8.5 3.8 0.46 10.4 0.6 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Peptidase_S28 PF05577.12 EMC90840.1 - 7.6e-44 150.2 4.3 8e-43 146.8 4.3 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Asp PF00026.23 EMC90841.1 - 5.9e-48 163.9 2.2 8.9e-48 163.3 2.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMC90841.1 - 2.9e-10 40.7 7.0 2.1e-09 37.9 1.9 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EMC90841.1 - 0.0099 16.4 0.1 0.76 10.4 0.1 3.6 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease NPR3 PF03666.13 EMC90843.1 - 0.74 8.5 3.8 1.2 7.8 3.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SKG6 PF08693.10 EMC90844.1 - 0.076 12.4 2.2 0.25 10.8 2.2 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cytochrom_B561 PF03188.16 EMC90845.1 - 1.8e-08 34.6 8.0 3.2e-08 33.8 8.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EMC90845.1 - 0.0012 18.6 2.3 0.0012 18.6 2.3 2.2 1 1 2 3 3 3 1 Domain of unknown function (DUF2427) Ni_hydr_CYTB PF01292.20 EMC90845.1 - 0.049 13.2 10.0 0.93 9.1 10.0 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF418 PF04235.12 EMC90845.1 - 0.17 11.8 6.7 0.25 11.3 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) DUF373 PF04123.13 EMC90845.1 - 0.17 11.3 1.2 0.22 10.9 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4079 PF13301.6 EMC90845.1 - 3.4 7.8 11.1 1.1 9.4 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) CDH-cyt PF16010.5 EMC90846.1 - 2.8e-17 63.0 0.1 4e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Sugar_tr PF00083.24 EMC90847.1 - 1.4e-108 363.7 20.8 1.4e-108 363.7 20.7 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMC90847.1 - 4.6e-20 71.8 49.4 4.3e-18 65.4 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMC90847.1 - 0.007 14.7 0.7 0.007 14.7 0.7 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Phage_T4_gp36 PF03903.13 EMC90848.1 - 0.014 15.4 0.1 0.071 13.1 0.0 2.1 2 1 0 2 2 2 0 Phage T4 tail fibre SLX9 PF15341.6 EMC90853.1 - 2.9e-31 108.6 2.6 4e-31 108.1 2.6 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Zn_ribbon_SprT PF17283.2 EMC90856.1 - 0.055 13.4 13.3 0.29 11.1 0.3 3.2 1 1 2 3 3 3 0 SprT-like zinc ribbon domain C1_2 PF03107.16 EMC90856.1 - 0.059 13.7 7.3 0.071 13.4 7.3 1.1 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 EMC90856.1 - 0.13 12.4 7.8 0.37 11.0 7.8 1.7 1 1 0 1 1 1 0 B-box zinc finger Zn-ribbon_8 PF09723.10 EMC90856.1 - 0.33 11.1 8.9 1.8 8.8 0.1 3.0 2 1 0 2 2 2 0 Zinc ribbon domain ECH_2 PF16113.5 EMC90858.1 - 0.09 12.3 0.1 0.09 12.3 0.1 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase MoeA_C PF03454.15 EMC90859.1 - 0.04 14.1 0.9 0.057 13.6 0.1 1.6 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) RNA_ligase PF09414.10 EMC90866.1 - 0.0062 16.9 0.0 0.038 14.3 0.0 2.0 1 1 0 1 1 1 1 RNA ligase Peroxidase_2 PF01328.17 EMC90870.1 - 2.5e-42 145.5 0.0 3.2e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF4188 PF13826.6 EMC90873.1 - 3.8e-33 114.3 0.0 6.6e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EMC90873.1 - 0.031 13.7 1.4 0.043 13.2 1.4 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase Nucleo_P87 PF07267.11 EMC90874.1 - 3.7 6.3 5.4 6.4 5.5 5.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PapG_C PF03628.13 EMC90877.1 - 0.09 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 PapG chaperone-binding domain GDPD PF03009.17 EMC90878.1 - 2.5e-30 106.1 0.0 3e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Transformer PF06495.11 EMC90883.1 - 0.21 11.7 14.8 0.31 11.1 14.8 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein GREB1 PF15782.5 EMC90883.1 - 0.89 6.6 31.0 0.85 6.7 31.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 EMC90883.1 - 1.8 7.6 37.7 1.8 7.5 37.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SOBP PF15279.6 EMC90883.1 - 3.4 8.2 21.8 4.4 7.8 21.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Pilosulin PF17499.2 EMC90883.1 - 3.9 7.7 22.6 1.4 9.2 5.3 2.9 2 1 1 3 3 3 0 Ant venom peptides Hid1 PF12722.7 EMC90883.1 - 6.3 4.8 31.2 7.3 4.6 31.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Trypan_PARP PF05887.11 EMC90883.1 - 8.5 6.4 33.5 2.7 8.0 23.3 2.7 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.13 EMC90883.1 - 9.8 6.1 41.6 13 5.6 41.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBM_6 PF03422.15 EMC90884.1 - 0.014 15.7 0.7 6.6 7.1 0.0 2.2 1 1 1 2 2 2 0 Carbohydrate binding module (family 6) ALMT PF11744.8 EMC90885.1 - 0.023 13.5 1.6 0.031 13.1 1.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter GBP_C PF02841.14 EMC90885.1 - 0.037 13.4 8.4 0.062 12.7 8.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF1682 PF07946.14 EMC90885.1 - 0.04 13.1 13.2 0.07 12.3 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Helicase_C PF00271.31 EMC90885.1 - 0.062 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain NARP1 PF12569.8 EMC90885.1 - 6.5 5.5 14.3 9.8 4.9 14.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Plasmodium_HRP PF05403.11 EMC90886.1 - 0.34 10.7 20.9 0.59 9.9 20.9 1.3 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) COX7B PF05392.11 EMC90892.1 - 0.25 11.1 1.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB GramPos_pilinD1 PF16555.5 EMC90897.1 - 0.19 11.9 0.4 0.39 10.9 0.4 1.4 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain DUF3827 PF12877.7 EMC90899.1 - 0.082 11.3 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Noelin-1 PF12308.8 EMC90899.1 - 7.4 6.6 7.0 7.2 6.7 3.8 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein Spem1 PF15670.5 EMC90901.1 - 0.32 10.5 4.3 0.14 11.7 1.8 1.6 2 0 0 2 2 2 0 Spermatid maturation protein 1 Hol_Tox PF16935.5 EMC90905.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative Holin-like Toxin (Hol-Tox) Peptidase_C48 PF02902.19 EMC90913.1 - 3.9e-12 46.5 0.1 5.7e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zinc_ribbon_12 PF11331.8 EMC90914.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.1 2 1 1 3 3 3 0 Probable zinc-ribbon domain Ebola_NP PF05505.12 EMC90914.1 - 0.16 10.2 1.5 0.2 9.9 1.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein PKcGMP_CC PF16808.5 EMC90915.1 - 5.8e-06 26.1 15.4 0.068 13.0 1.3 5.2 5 0 0 5 5 5 2 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 EMC90915.1 - 0.014 15.7 12.1 0.014 15.7 12.1 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 EMC90915.1 - 0.045 13.1 13.8 0.11 11.9 3.9 2.1 1 1 1 2 2 2 0 FAM76 protein BBP1_C PF15272.6 EMC90915.1 - 0.075 12.8 14.8 0.6 9.9 1.5 3.1 1 1 3 4 4 4 0 Spindle pole body component BBP1, C-terminal Fib_alpha PF08702.10 EMC90915.1 - 0.089 13.0 6.6 0.24 11.6 2.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 EMC90915.1 - 0.43 10.6 11.0 2.6 8.1 0.7 3.4 1 1 1 3 3 3 0 FlxA-like protein DUF4315 PF14193.6 EMC90915.1 - 0.71 9.9 5.7 0.55 10.3 1.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) Lebercilin PF15619.6 EMC90915.1 - 0.74 9.4 20.6 0.42 10.2 15.0 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EMC90915.1 - 0.97 8.2 15.2 0.82 8.5 9.2 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EMC90915.1 - 0.99 9.7 15.6 21 5.5 0.1 4.5 2 2 2 4 4 4 0 ABC transporter C-terminal domain SlyX PF04102.12 EMC90915.1 - 1 10.0 18.4 1.1 9.9 0.3 4.4 3 2 1 4 4 4 0 SlyX Jnk-SapK_ap_N PF09744.9 EMC90915.1 - 1.3 9.2 14.6 5.3 7.3 0.5 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CLZ PF16526.5 EMC90915.1 - 1.7 9.0 7.2 0.53 10.7 1.7 2.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CEP209_CC5 PF16574.5 EMC90915.1 - 1.9 8.7 13.7 0.078 13.1 5.7 2.4 2 1 1 3 3 3 0 Coiled-coil region of centrosome protein CE290 DUF641 PF04859.12 EMC90915.1 - 2.1 8.7 8.1 3.1 8.2 0.7 3.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FapA PF03961.13 EMC90915.1 - 3 6.3 5.7 3.7 6.1 4.8 1.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A UPF0231 PF06062.11 EMC90915.1 - 3.2 8.0 11.5 4.1 7.7 1.3 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0231) DHR10 PF18595.1 EMC90915.1 - 3.7 7.6 23.8 0.17 11.9 2.8 3.5 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain ZapB PF06005.12 EMC90915.1 - 3.8 8.0 16.3 0.4 11.1 1.6 3.5 2 1 1 3 3 3 0 Cell division protein ZapB Pox_A_type_inc PF04508.12 EMC90915.1 - 3.9 7.5 8.7 7.9 6.5 0.2 4.1 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat JIP_LZII PF16471.5 EMC90915.1 - 5.5 7.2 8.5 17 5.7 0.6 3.1 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 EMC90915.1 - 6.7 6.8 19.7 0.3 11.1 5.9 3.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.14 EMC90915.1 - 7.7 6.3 7.4 6.4 6.5 0.2 3.1 2 1 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EMC90915.1 - 7.8 6.6 8.0 14 5.7 0.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 EMC90915.1 - 9.9 6.2 15.4 8.6e+02 -0.1 15.4 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EMC90922.1 - 0.17 11.4 19.3 0.36 10.4 16.8 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit FAM76 PF16046.5 EMC90922.1 - 2.6 7.3 7.6 6.1 6.1 7.6 1.7 1 0 0 1 1 1 0 FAM76 protein Tup_N PF08581.10 EMC90925.1 - 0.023 15.0 3.9 0.054 13.8 3.9 1.6 1 0 0 1 1 1 0 Tup N-terminal DUF3614 PF12267.8 EMC90925.1 - 0.024 15.2 3.3 0.046 14.2 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) STN1_2 PF09170.10 EMC90925.1 - 0.025 14.8 0.7 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 SPATA19 PF15212.6 EMC90925.1 - 0.16 12.2 3.2 0.3 11.3 3.2 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial DUF4778 PF16008.5 EMC90925.1 - 0.17 11.9 4.8 0.26 11.3 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF1365 PF07103.11 EMC90926.1 - 0.075 12.7 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) DUF4553 PF15090.6 EMC90927.1 - 0.43 9.5 32.3 0.61 9.0 32.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) SWI-SNF_Ssr4 PF08549.10 EMC90927.1 - 3.3 6.3 21.0 4.2 5.9 21.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Macoilin PF09726.9 EMC90927.1 - 3.5 6.1 29.6 4.6 5.7 29.6 1.1 1 0 0 1 1 1 0 Macoilin family CDC27 PF09507.10 EMC90927.1 - 8 5.7 41.9 12 5.1 41.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PT PF04886.12 EMC90930.1 - 0.35 10.4 8.9 3.4 7.3 0.2 2.2 2 0 0 2 2 2 0 PT repeat GalKase_gal_bdg PF10509.9 EMC90934.1 - 0.031 13.8 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Galactokinase galactose-binding signature Peptidase_C48 PF02902.19 EMC90943.1 - 6.4e-06 26.2 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PI3K_P85_iSH2 PF16454.5 EMC90943.1 - 0.047 13.3 0.2 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ubiquitin PF00240.23 EMC90944.1 - 3.1e-09 36.4 0.0 0.00027 20.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.6 EMC90944.1 - 1.1e-06 29.0 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.10 EMC90944.1 - 0.072 13.8 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ALP_N PF17989.1 EMC90946.1 - 0.16 12.1 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Actin like proteins N terminal domain Zn_clus PF00172.18 EMC90950.1 - 4.1e-05 23.6 7.7 8.8e-05 22.6 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C48 PF02902.19 EMC90953.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF5542 PF17696.1 EMC90954.1 - 0.13 12.4 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DUF5056 PF16479.5 EMC90958.1 - 0.21 11.9 0.8 0.6 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) DUF5438 PF17506.2 EMC90958.1 - 0.35 11.2 2.6 0.76 10.1 0.7 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5438) CBM64 PF18666.1 EMC90964.1 - 0.039 14.0 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate-binding module 64 GLTT PF01744.20 EMC90970.1 - 0.0034 17.1 2.6 0.055 13.2 0.1 3.0 3 0 0 3 3 3 2 GLTT repeat (6 copies) Ribosomal_S19e PF01090.19 EMC90977.1 - 0.16 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e Peptidase_C48 PF02902.19 EMC90981.1 - 6.7e-05 22.8 0.1 7.2e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain S6OS1 PF15676.5 EMC90981.1 - 0.042 12.3 0.0 0.046 12.2 0.0 1.0 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Peptidase_C48 PF02902.19 EMC90987.1 - 5.7e-07 29.6 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TetR_C_34 PF17929.1 EMC90987.1 - 0.0085 16.2 0.2 0.021 14.9 0.2 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF4279 PF14106.6 EMC90987.1 - 0.025 14.8 0.7 1.4 9.2 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) MIS13 PF08202.11 EMC90987.1 - 0.085 12.1 0.7 0.17 11.1 0.2 1.7 1 1 0 2 2 2 0 Mis12-Mtw1 protein family YojJ PF10372.9 EMC90987.1 - 0.3 11.2 0.8 1.7 8.8 0.1 2.4 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus ExsD PF16806.5 EMC90987.1 - 0.36 10.7 3.9 0.15 11.9 0.7 1.8 1 1 1 2 2 2 0 Antiactivator protein ExsD ATG16 PF08614.11 EMC90987.1 - 7.9 6.6 9.2 6.4 6.9 5.4 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) K_channel_TID PF07941.11 EMC91000.1 - 0.00011 22.5 0.7 0.00011 22.5 0.7 2.8 3 1 1 4 4 4 1 Potassium channel Kv1.4 tandem inactivation domain PetM PF08041.11 EMC91002.1 - 0.1 12.2 0.3 0.1 12.2 0.3 1.6 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 DUF4083 PF13314.6 EMC91005.1 - 0.16 11.9 0.6 0.39 10.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Dynamin_N PF00350.23 EMC91006.1 - 3.3e-09 37.0 0.6 6.7e-08 32.8 0.0 2.8 1 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EMC91006.1 - 3.5e-06 27.1 0.1 0.01 15.9 0.0 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMC91006.1 - 0.00063 19.7 1.3 0.016 15.1 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 EMC91006.1 - 0.0055 17.2 0.2 0.34 11.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EMC91006.1 - 0.011 16.1 0.6 0.04 14.3 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain HcyBio PF01837.16 EMC91006.1 - 0.022 13.6 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation AAA_33 PF13671.6 EMC91006.1 - 0.036 14.2 1.2 0.13 12.4 0.0 2.6 4 0 0 4 4 4 0 AAA domain Mucin_bdg PF03272.13 EMC91006.1 - 0.085 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module AAA_22 PF13401.6 EMC91006.1 - 0.59 10.4 2.3 4.4 7.6 0.0 3.3 4 1 0 4 4 4 0 AAA domain Importin_rep_6 PF18829.1 EMC91006.1 - 2.6 8.2 6.4 0.43 10.7 0.1 2.8 3 0 0 3 3 3 0 Importin repeat 6 JmjC PF02373.22 EMC91010.1 - 3.8e-24 85.3 0.1 9.9e-24 84.0 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EMC91010.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Cupin domain SIR2 PF02146.17 EMC91022.1 - 2.8e-25 89.2 0.0 3.9e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF2635 PF10948.8 EMC91024.1 - 0.093 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) DUF2378 PF09536.10 EMC91025.1 - 0.12 12.2 0.0 0.77 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) Peptidase_C48 PF02902.19 EMC91038.1 - 6.4e-05 22.9 0.3 0.00015 21.7 0.3 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cas_Cas5d PF09704.10 EMC91040.1 - 0.093 12.6 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) adh_short_C2 PF13561.6 EMC91053.1 - 9.8e-68 228.2 3.6 1.1e-67 228.0 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC91053.1 - 5.2e-53 179.4 1.0 6.5e-53 179.1 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC91053.1 - 7e-11 42.4 0.7 9.8e-11 41.9 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC91053.1 - 0.0013 18.2 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EMC91053.1 - 0.0094 15.9 0.1 0.023 14.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1776 PF08643.10 EMC91053.1 - 0.032 13.6 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fungal_trans_2 PF11951.8 EMC91054.1 - 3e-58 197.5 0.0 4.2e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Far-17a_AIG1 PF04750.14 EMC91055.1 - 1.1e-56 191.4 10.2 1.3e-56 191.2 10.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Glyco_transf_8 PF01501.20 EMC91056.1 - 0.0044 16.6 1.3 0.74 9.3 0.0 3.1 3 1 0 3 3 3 2 Glycosyl transferase family 8 Bul1_N PF04425.12 EMC91056.1 - 0.029 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Bul1 N terminus PmbA_TldD PF01523.16 EMC91056.1 - 0.13 12.1 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase AP1AR PF15745.5 EMC91056.1 - 0.14 11.8 4.7 0.22 11.1 4.7 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein MFS_1 PF07690.16 EMC91057.1 - 6e-24 84.6 26.9 6e-24 84.6 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.8 EMC91057.1 - 9.1 6.3 5.6 1.4 9.0 0.1 2.3 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FMO-like PF00743.19 EMC91058.1 - 2.5e-41 141.7 0.0 1e-24 86.9 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMC91058.1 - 3.6e-16 59.3 0.0 5.2e-11 42.4 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC91058.1 - 3.1e-10 39.8 0.0 8.5e-10 38.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC91058.1 - 2.8e-07 30.7 0.3 0.00018 21.6 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMC91058.1 - 1.2e-06 28.6 0.0 2.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC91058.1 - 3.6e-06 26.8 0.6 0.0062 16.2 0.6 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EMC91058.1 - 3.9e-06 26.3 0.0 3.5e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EMC91058.1 - 4.1e-06 26.2 0.3 0.00014 21.2 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) MCRA PF06100.11 EMC91058.1 - 0.0001 21.3 0.4 0.32 9.7 0.2 2.2 2 0 0 2 2 2 2 MCRA family HI0933_like PF03486.14 EMC91058.1 - 0.00083 18.2 0.1 0.14 10.9 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMC91058.1 - 0.0046 16.1 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 EMC91058.1 - 0.006 15.9 0.1 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EMC91058.1 - 0.01 15.1 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 EMC91058.1 - 0.16 12.0 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase SprT-like PF10263.9 EMC91059.1 - 7.3e-08 32.3 0.1 1.1e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 SprT-like family BSP PF04450.12 EMC91059.1 - 0.0044 16.8 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase of plants and bacteria FGAR-AT_N PF18076.1 EMC91059.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal SprT-like PF10263.9 EMC91060.1 - 4.4e-07 29.8 0.0 8.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Sulfatase PF00884.23 EMC91063.1 - 1.5e-45 155.9 5.3 5.4e-23 81.8 0.5 2.5 2 1 1 3 3 3 2 Sulfatase Phosphodiest PF01663.22 EMC91063.1 - 3.2e-08 33.6 0.7 2.6e-07 30.5 0.7 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EMC91063.1 - 0.0021 18.3 4.9 0.078 13.3 0.2 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4976) UL45 PF05473.12 EMC91064.1 - 0.072 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DAGAT PF03982.13 EMC91065.1 - 8.1e-90 300.7 0.0 1e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Stk19 PF10494.9 EMC91066.1 - 9.3e-79 264.6 0.0 1.2e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 PLDc_2 PF13091.6 EMC91067.1 - 1.9e-22 79.6 0.0 1.2e-12 47.9 0.1 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EMC91067.1 - 0.0015 18.6 0.4 0.07 13.3 0.1 3.0 2 0 0 2 2 2 1 Phospholipase D Active site motif FMO-like PF00743.19 EMC91068.1 - 9.3e-14 50.7 0.0 6.5e-10 38.0 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMC91068.1 - 1.8e-13 50.4 0.0 5.8e-12 45.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMC91068.1 - 5.4e-13 48.9 0.0 2.5e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC91068.1 - 2.6e-08 33.5 0.0 2.3e-06 27.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC91068.1 - 2.1e-07 31.1 1.0 2.8e-05 24.2 0.3 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EMC91068.1 - 1.9e-05 24.4 0.0 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC91068.1 - 0.0016 18.6 0.1 0.0046 17.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC91068.1 - 0.0031 18.0 0.1 10 6.7 0.0 3.6 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC91068.1 - 0.0057 15.4 0.0 0.35 9.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EMC91068.1 - 0.0067 15.5 0.2 0.05 12.7 0.1 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EMC91068.1 - 0.013 14.7 0.0 0.087 12.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.15 EMC91068.1 - 0.034 12.7 0.0 0.55 8.7 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 EMC91068.1 - 0.075 12.1 0.0 1 8.3 0.0 2.0 1 1 1 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 EMC91068.1 - 0.09 12.1 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF4147 PF13660.6 EMC91068.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Pkinase PF00069.25 EMC91069.1 - 4.2e-62 209.9 0.0 5.1e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC91069.1 - 4.4e-32 111.4 0.0 5.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC91069.1 - 0.00036 19.9 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EMC91069.1 - 0.047 12.6 0.0 0.11 11.4 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EMC91069.1 - 0.05 12.4 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EMC91069.1 - 0.055 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family IGR PF09597.10 EMC91070.1 - 2.4e-25 88.4 0.0 4.8e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 IGR protein motif GIT_SHD PF08518.11 EMC91071.1 - 0.00093 18.8 1.7 0.31 10.7 0.0 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF2242 PF10001.9 EMC91071.1 - 0.33 11.1 1.5 0.82 9.9 1.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) adh_short PF00106.25 EMC91072.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Kinesin PF00225.23 EMC91073.1 - 6.5e-93 311.3 0.0 2.8e-92 309.2 0.0 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMC91073.1 - 5.1e-21 75.2 0.0 1.3e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding PKcGMP_CC PF16808.5 EMC91073.1 - 0.011 15.6 0.8 0.011 15.6 0.8 3.3 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 EMC91073.1 - 1 8.7 10.9 0.76 9.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4051 PF13260.6 EMC91074.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DHQ_synthase PF01761.20 EMC91075.1 - 2.7e-52 177.5 0.0 4e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EMC91075.1 - 5.1e-11 42.8 0.0 8.1e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EMC91075.1 - 0.0066 15.3 0.0 0.01 14.7 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.17 EMC91076.1 - 6.9e-12 45.0 0.0 9.4e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EMC91076.1 - 1.1e-09 39.3 0.0 2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 EMC91076.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase HCV_NS5a_C PF12941.7 EMC91077.1 - 0.056 13.3 0.2 0.097 12.5 0.2 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region Metallophos PF00149.28 EMC91078.1 - 1e-12 49.0 0.2 1.8e-12 48.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RNase_H PF00075.24 EMC91080.1 - 1.3e-14 54.6 0.0 3.4e-14 53.2 0.0 1.6 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EMC91080.1 - 0.0038 17.0 0.0 0.053 13.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like Glyco_transf_34 PF05637.12 EMC91082.1 - 3.6e-16 59.6 0.6 1.1e-12 48.3 0.6 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EMC91082.1 - 0.0069 16.0 0.1 0.034 13.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 EMC91082.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Cytochrom_C1 PF02167.15 EMC91083.1 - 2.1e-94 315.3 0.0 2.6e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EMC91083.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EMC91083.1 - 0.15 13.2 0.1 1.3 10.2 0.0 2.5 3 0 0 3 3 3 0 Cytochrome c Methyltransf_11 PF08241.12 EMC91084.1 - 7.5e-25 87.4 0.0 1.2e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC91084.1 - 1.2e-23 83.5 0.0 1.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC91084.1 - 2.9e-23 82.4 0.0 5.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC91084.1 - 3.6e-18 65.8 0.0 5.1e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMC91084.1 - 8.3e-17 61.8 0.0 1.3e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC91084.1 - 6e-15 55.5 0.0 8.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC91084.1 - 4e-08 33.0 0.0 7.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EMC91084.1 - 3e-05 23.3 0.0 4.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 EMC91084.1 - 0.0006 19.6 0.0 0.00091 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EMC91084.1 - 0.00063 19.4 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 EMC91084.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EMC91084.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EMC91084.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Bmt2 PF11968.8 EMC91084.1 - 0.0028 17.6 0.0 0.0085 16.0 0.0 1.7 1 1 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 CheR PF01739.18 EMC91084.1 - 0.0032 17.0 0.0 1.1 8.7 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 EMC91084.1 - 0.0037 16.7 0.0 0.0091 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 EMC91084.1 - 0.005 16.9 0.0 0.0077 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EMC91084.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 EMC91084.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF938 PF06080.12 EMC91084.1 - 0.031 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_29 PF03141.16 EMC91084.1 - 0.047 12.3 0.0 0.078 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 EMC91084.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Acetyltransf_10 PF13673.7 EMC91085.1 - 7.6e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC91085.1 - 1.2e-05 25.5 0.0 3.8e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC91085.1 - 3.9e-05 24.0 0.0 8.1e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC91085.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 EMC91085.1 - 0.036 14.1 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_M20 PF01546.28 EMC91087.1 - 2.8e-27 95.8 0.2 4e-27 95.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMC91087.1 - 3.1e-19 68.9 0.0 7.7e-19 67.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMC91087.1 - 0.00011 21.9 0.0 0.04 13.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 PP_M1 PF03012.14 EMC91088.1 - 0.052 13.1 0.2 0.052 13.1 0.2 1.6 2 0 0 2 2 2 0 Phosphoprotein TetR_C_24 PF17932.1 EMC91089.1 - 0.054 13.8 0.0 0.79 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_2 PF07724.14 EMC91089.1 - 0.094 12.8 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HisG PF01634.18 EMC91093.1 - 5.7e-55 185.7 0.0 8e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EMC91093.1 - 2.5e-28 98.0 0.1 5.9e-28 96.8 0.1 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain Cellulase PF00150.18 EMC91094.1 - 4.2e-18 65.8 2.9 5.7e-18 65.3 2.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EMC91094.1 - 4.3e-05 22.8 0.0 0.00024 20.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Sugar_tr PF00083.24 EMC91096.1 - 3.2e-75 253.7 23.9 3.8e-75 253.5 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC91096.1 - 8.3e-31 107.2 62.0 1.4e-23 83.4 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.11 EMC91096.1 - 0.034 13.9 11.0 0.018 14.8 7.7 2.2 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Fungal_trans PF04082.18 EMC91097.1 - 6.4e-17 61.4 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC91097.1 - 7.4e-06 26.0 7.9 1.4e-05 25.1 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1772 PF08592.11 EMC91098.1 - 1.9e-31 109.2 0.3 3e-31 108.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DLH PF01738.18 EMC91099.1 - 2.7e-20 72.9 0.0 3.3e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EMC91099.1 - 0.0077 15.7 0.9 0.89 9.0 0.1 2.5 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EMC91099.1 - 0.052 13.2 0.7 0.14 11.8 0.4 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 EMC91099.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3141 PF11339.8 EMC91099.1 - 0.12 10.8 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DnaJ PF00226.31 EMC91100.1 - 8.5e-12 45.0 0.2 1.4e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 DnaJ domain PRA1 PF03208.19 EMC91101.1 - 4.2e-38 130.2 1.2 5.1e-38 129.9 1.2 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 EMC91101.1 - 0.23 10.2 0.9 0.25 10.1 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPC25 PF06703.11 EMC91101.1 - 0.37 10.6 1.8 0.69 9.7 0.3 2.2 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) RhoGAP PF00620.27 EMC91102.1 - 2.4e-41 141.1 0.1 4.5e-41 140.2 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EMC91102.1 - 1e-15 58.1 0.0 1.9e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EMC91102.1 - 0.0002 21.7 0.0 0.00049 20.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EMC91102.1 - 0.036 14.3 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain NTP_transf_9 PF04248.12 EMC91103.1 - 3.1e-46 155.2 0.2 1.1e-31 108.6 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Pkinase PF00069.25 EMC91104.1 - 9.6e-39 133.3 0.0 5.1e-28 98.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ribonuc_2-5A PF06479.12 EMC91104.1 - 1.1e-38 132.3 0.0 2.7e-38 131.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EMC91104.1 - 2.6e-20 72.8 0.0 2.6e-19 69.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 EMC91104.1 - 3.7e-05 23.4 0.2 0.0023 17.5 0.1 2.8 1 1 2 3 3 3 1 PQQ-like domain PQQ PF01011.21 EMC91104.1 - 0.00017 21.4 1.7 0.17 11.8 0.0 3.8 4 0 0 4 4 4 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 EMC91104.1 - 0.00055 18.8 0.0 0.017 13.9 0.0 2.3 1 1 1 2 2 2 1 Fungal protein kinase TSGP1 PF07771.11 EMC91104.1 - 2.2 8.5 5.2 4.9 7.3 5.2 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 APH PF01636.23 EMC91104.1 - 3.6 7.4 9.2 0.16 11.9 0.3 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family Orn_Arg_deC_N PF02784.16 EMC91106.1 - 9.8e-80 267.5 0.0 1.4e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EMC91106.1 - 4.2e-19 68.6 0.0 1.9e-17 63.3 0.0 2.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Chitin_synth_1N PF08407.11 EMC91106.1 - 0.049 13.6 0.1 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Chitin synthase N-terminal DUF5423 PF17461.2 EMC91106.1 - 1 8.2 5.4 1.6 7.5 5.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) zf-C3HC4_3 PF13920.6 EMC91107.1 - 4.4e-09 36.1 9.9 1.2e-08 34.7 7.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC91107.1 - 2.9e-08 33.4 8.7 2.9e-08 33.4 8.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC91107.1 - 6.8e-08 32.2 8.3 6.8e-08 32.2 8.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC91107.1 - 2e-07 31.3 9.0 2e-07 31.3 9.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EMC91107.1 - 5.8e-07 29.4 7.1 1.2e-06 28.4 7.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EMC91107.1 - 5.8e-07 29.6 9.8 5.8e-07 29.6 9.8 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMC91107.1 - 2.6e-06 27.3 8.8 2.6e-06 27.3 8.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EMC91107.1 - 9.1e-05 22.2 8.3 0.00039 20.2 5.3 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EMC91107.1 - 0.00023 21.0 2.8 0.00045 20.0 2.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EMC91107.1 - 0.0037 17.4 5.3 0.008 16.3 5.3 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 Papo_T_antigen PF02380.15 EMC91107.1 - 0.013 15.7 1.8 0.02 15.0 1.8 1.4 1 0 0 1 1 1 0 T-antigen specific domain DUF1272 PF06906.11 EMC91107.1 - 0.015 15.4 8.2 0.053 13.6 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) U-box PF04564.15 EMC91107.1 - 0.026 14.7 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 U-box domain DZR PF12773.7 EMC91107.1 - 0.1 12.6 12.1 3.3 7.8 7.3 2.8 1 1 1 2 2 2 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EMC91107.1 - 0.12 12.1 8.0 0.56 9.9 8.1 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FYVE PF01363.21 EMC91107.1 - 0.19 11.9 7.2 2.4 8.3 7.2 2.7 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.6 EMC91107.1 - 0.24 11.2 12.3 6.1 6.7 8.8 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain GAGA PF09237.11 EMC91107.1 - 0.48 10.3 3.3 0.67 9.8 0.9 2.3 2 0 0 2 2 2 0 GAGA factor zf-RING_7 PF02591.15 EMC91107.1 - 0.5 10.6 12.4 0.69 10.2 0.1 3.8 4 0 0 4 4 3 0 C4-type zinc ribbon domain zf-rbx1 PF12678.7 EMC91107.1 - 0.59 10.5 14.4 0.071 13.4 8.8 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain zinc-ribbons_6 PF07191.12 EMC91107.1 - 1.2 9.1 10.1 2.1 8.4 6.1 2.4 2 1 0 2 2 2 0 zinc-ribbons Ribosomal_S27e PF01667.17 EMC91107.1 - 1.7 8.4 0.0 1.7 8.4 0.0 3.2 4 0 0 4 4 4 0 Ribosomal protein S27 RecR PF02132.15 EMC91107.1 - 2.6 7.7 10.0 16 5.1 3.6 3.3 3 1 0 3 3 3 0 RecR protein HypA PF01155.19 EMC91107.1 - 4.6 7.3 8.2 39 4.3 5.8 2.9 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ArfGap PF01412.18 EMC91108.1 - 2.4e-37 127.6 1.1 5.1e-37 126.5 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 EMC91108.1 - 0.00075 19.4 0.1 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UPF0242 PF06785.11 EMC91109.1 - 1 9.4 4.6 1.7 8.7 4.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NatB_MDM20 PF09797.9 EMC91110.1 - 3.8e-35 121.5 0.1 3.3e-34 118.5 0.0 2.1 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Hemerythrin PF01814.23 EMC91110.1 - 0.049 14.3 0.2 0.45 11.1 0.0 2.6 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF416 PF04222.12 EMC91110.1 - 0.097 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Fis1_TPR_C PF14853.6 EMC91110.1 - 0.14 12.2 0.5 6.1 7.0 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Methyltransf_16 PF10294.9 EMC91111.1 - 4.6e-45 153.5 0.0 5.5e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EMC91111.1 - 4.8e-08 32.9 0.0 6.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC91111.1 - 4.6e-05 24.0 0.0 7.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EMC91111.1 - 0.0012 18.2 0.0 0.0052 16.1 0.0 1.6 1 1 1 2 2 2 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EMC91111.1 - 0.0014 19.4 0.0 0.0023 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC91111.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EMC91111.1 - 0.014 16.0 0.0 0.024 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF202 PF02656.15 EMC91113.1 - 2.6e-15 56.6 2.5 2.6e-15 56.6 2.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Peptidase_M18 PF02127.15 EMC91114.1 - 1.2e-161 538.4 0.0 4.5e-161 536.4 0.0 1.7 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Ribosomal_S28e PF01200.18 EMC91116.1 - 3.5e-31 107.0 2.3 3.9e-31 106.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Fungal_trans_2 PF11951.8 EMC91118.1 - 1.7e-11 43.6 0.0 2.7e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_4 PF01063.19 EMC91119.1 - 1.5e-20 74.0 0.0 1.9e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Evr1_Alr PF04777.13 EMC91120.1 - 9.1e-27 93.5 0.1 1.1e-26 93.2 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Abhydrolase_1 PF00561.20 EMC91121.1 - 2.8e-12 46.8 0.1 6.5e-11 42.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold EXS PF03124.14 EMC91122.1 - 1.7e-91 307.0 14.5 2e-91 306.8 14.5 1.0 1 0 0 1 1 1 1 EXS family Fe-ADH PF00465.19 EMC91123.1 - 1.1e-68 231.7 0.0 1.5e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMC91123.1 - 2.5e-05 24.1 0.0 0.0056 16.4 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase TMEM171 PF15471.6 EMC91125.1 - 0.37 9.7 4.6 1.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF5345 PF17280.2 EMC91125.1 - 0.82 9.7 2.1 20 5.3 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) GMC_oxred_N PF00732.19 EMC91126.1 - 1.7e-65 221.3 0.0 2.3e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC91126.1 - 2.1e-31 109.4 0.0 3.9e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMC91126.1 - 7.7e-06 25.2 0.4 1.2e-05 24.5 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMC91126.1 - 0.00053 19.2 0.3 0.0041 16.3 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EMC91126.1 - 0.0026 17.0 0.2 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EMC91126.1 - 0.0031 17.2 2.3 0.024 14.2 2.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC91126.1 - 0.0042 17.3 0.1 0.013 15.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GDI PF00996.18 EMC91126.1 - 0.021 13.4 0.1 2.3 6.6 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor DUF5023 PF16426.5 EMC91126.1 - 0.041 13.5 0.3 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5023) Pyr_redox_2 PF07992.14 EMC91126.1 - 0.083 12.1 0.1 0.55 9.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PARP PF00644.20 EMC91128.1 - 1.7e-06 27.7 0.0 2.2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Zn_clus PF00172.18 EMC91129.1 - 7.6e-08 32.4 8.0 1.3e-07 31.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 EMC91130.1 - 1.4e-115 386.2 0.0 9.2e-111 370.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III Beta_elim_lyase PF01212.21 EMC91130.1 - 0.013 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EMC91130.1 - 0.028 13.6 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_hydro_30 PF02055.16 EMC91131.1 - 7.5e-12 44.9 0.0 7.5e-12 44.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 EMC91131.1 - 1.5e-07 31.5 2.4 5.2e-07 29.8 2.4 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 EMC91131.1 - 4.3e-05 22.9 0.0 7.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 MFS_1 PF07690.16 EMC91132.1 - 3.4e-26 92.0 34.4 5.4e-26 91.4 34.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC91132.1 - 3.3e-18 65.8 6.8 3.3e-18 65.8 6.8 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter FAD_binding_3 PF01494.19 EMC91133.1 - 3.1e-27 95.7 0.0 5.5e-27 94.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC91133.1 - 7e-11 42.3 6.5 4.6e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC91133.1 - 3.9e-07 29.6 0.0 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMC91133.1 - 2.4e-05 23.8 0.5 0.00059 19.2 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EMC91133.1 - 0.00013 20.8 0.4 0.04 12.6 1.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMC91133.1 - 0.00053 19.2 4.9 0.0009 18.4 4.9 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMC91133.1 - 0.00061 20.0 3.6 0.00087 19.5 2.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMC91133.1 - 0.0049 16.0 1.4 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 EMC91133.1 - 0.03 13.7 2.1 0.046 13.1 2.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMC91133.1 - 0.033 13.1 1.6 0.79 8.5 0.7 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 EMC91133.1 - 0.038 14.5 0.2 5.3 7.7 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EMC91133.1 - 0.039 13.0 0.0 0.69 8.9 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 EMC91133.1 - 0.051 12.6 1.2 0.08 12.0 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMC91133.1 - 0.087 12.1 0.3 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GspH PF12019.8 EMC91133.1 - 0.12 12.9 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 Type II transport protein GspH 3HCDH_N PF02737.18 EMC91133.1 - 0.2 11.5 0.3 0.32 10.8 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3500 PF12006.8 EMC91134.1 - 3.8e-94 315.5 0.0 4.5e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) AAA PF00004.29 EMC91135.1 - 5e-53 179.0 0.0 1.6e-42 145.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EMC91135.1 - 7.4e-26 90.4 0.8 2e-25 89.0 0.8 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EMC91135.1 - 9e-13 47.8 2.3 1e-06 28.4 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EMC91135.1 - 7.9e-10 39.4 8.0 0.00011 22.6 0.3 4.8 3 2 1 4 4 3 2 AAA ATPase domain NACHT PF05729.12 EMC91135.1 - 6.3e-09 36.0 0.5 4e-06 26.8 0.1 3.1 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 EMC91135.1 - 5.3e-06 26.3 0.0 0.013 15.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMC91135.1 - 1.5e-05 25.2 0.0 0.007 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 EMC91135.1 - 4e-05 23.6 0.1 0.091 12.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EMC91135.1 - 4.1e-05 23.9 1.6 0.24 11.7 0.2 4.1 2 2 1 3 3 3 2 AAA domain AAA_7 PF12775.7 EMC91135.1 - 0.00012 21.6 0.0 0.0081 15.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 EMC91135.1 - 0.00016 21.7 0.1 0.97 9.4 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EMC91135.1 - 0.00022 21.0 0.1 0.21 11.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EMC91135.1 - 0.00039 20.5 0.0 0.71 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EMC91135.1 - 0.00054 19.3 0.0 0.18 11.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 EMC91135.1 - 0.00066 19.9 0.0 0.22 11.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMC91135.1 - 0.00066 20.2 0.1 1.9 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EMC91135.1 - 0.002 18.4 0.0 0.6 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EMC91135.1 - 0.0024 17.6 0.0 0.16 11.7 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 EMC91135.1 - 0.0058 15.9 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 EMC91135.1 - 0.011 15.1 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 EMC91135.1 - 0.011 16.1 0.0 4.8 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EMC91135.1 - 0.015 15.8 0.3 6 7.4 0.0 2.9 3 0 0 3 3 2 0 ABC transporter DUF2075 PF09848.9 EMC91135.1 - 0.021 14.1 0.0 4.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.22 EMC91135.1 - 0.029 14.5 0.0 6.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase ATPase_2 PF01637.18 EMC91135.1 - 0.033 14.1 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EMC91135.1 - 0.04 13.3 0.2 0.76 9.1 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMC91135.1 - 0.051 13.1 5.8 1.3 8.6 0.0 4.3 4 1 1 5 5 5 0 AAA domain Sigma54_activ_2 PF14532.6 EMC91135.1 - 0.053 13.6 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 EMC91135.1 - 0.066 12.7 0.1 12 5.2 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein Cytidylate_kin2 PF13189.6 EMC91135.1 - 0.074 13.2 0.1 8.7 6.4 0.0 3.0 3 0 0 3 3 2 0 Cytidylate kinase-like family PEX-2N PF09263.10 EMC91135.1 - 0.079 13.3 2.7 3.7 7.9 0.9 3.2 2 1 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal AAA_17 PF13207.6 EMC91135.1 - 0.1 13.1 0.1 2.3 8.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 EMC91135.1 - 0.13 12.3 0.1 1.7 8.7 0.0 2.8 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain AAA_19 PF13245.6 EMC91135.1 - 0.14 12.4 0.1 2 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EMC91135.1 - 0.17 11.1 0.0 12 5.0 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.19 EMC91135.1 - 0.24 11.0 0.5 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thioredoxin_7 PF13899.6 EMC91136.1 - 2.6e-15 56.3 0.0 6.2e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EMC91136.1 - 1.1e-13 50.8 0.2 2.9e-13 49.4 0.2 1.8 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EMC91136.1 - 5.8e-07 29.6 0.0 1.9e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 UBX domain Thioredox_DsbH PF03190.15 EMC91136.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 PepSY_TM PF03929.16 EMC91136.1 - 0.62 9.7 0.0 0.62 9.7 0.0 1.9 2 1 0 2 2 2 0 PepSY-associated TM region ERAP1_C PF11838.8 EMC91137.1 - 4.4e-87 292.6 4.5 5.6e-86 288.9 0.7 2.5 2 1 1 3 3 3 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EMC91137.1 - 6.3e-83 277.6 0.2 1.1e-82 276.9 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EMC91137.1 - 1.9e-54 184.7 1.1 6.7e-54 182.9 0.9 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EMC91137.1 - 0.021 14.8 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF1081 PF06448.11 EMC91137.1 - 0.062 13.7 0.6 0.13 12.6 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1081) 4HBT_3 PF13622.6 EMC91138.1 - 4.6e-53 181.0 0.2 5.3e-53 180.8 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EMC91138.1 - 0.00019 21.7 0.1 0.00039 20.7 0.1 1.6 1 0 0 1 1 1 1 Thioesterase superfamily ArfGap PF01412.18 EMC91139.1 - 5.1e-35 120.1 3.6 1.2e-34 118.9 0.0 2.9 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EMC91139.1 - 6.4e-17 62.1 15.5 6.4e-17 62.1 15.5 1.5 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 EMC91139.1 - 1.4e-11 44.8 0.0 6.2e-11 42.7 0.0 2.1 1 0 0 1 1 1 1 PH domain HIG_1_N PF04588.13 EMC91140.1 - 0.074 13.3 0.1 0.074 13.3 0.1 1.8 2 0 0 2 2 2 0 Hypoxia induced protein conserved region MFS_1 PF07690.16 EMC91141.1 - 8.5e-31 107.2 21.8 8.5e-31 107.2 21.8 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily NAD_Gly3P_dh_N PF01210.23 EMC91142.1 - 2e-45 154.6 0.0 6.2e-45 153.0 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EMC91142.1 - 2.7e-42 144.4 0.0 4.1e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Methyltransf_25 PF13649.6 EMC91143.1 - 7.4e-06 26.6 0.0 1.5e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC91143.1 - 0.031 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EMC91143.1 - 0.07 13.9 0.0 0.23 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EMC91143.1 - 0.094 13.4 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FSA_C PF10479.9 EMC91144.1 - 2.7 6.0 12.4 5.1 5.1 12.4 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Fcf1 PF04900.12 EMC91145.1 - 2.3e-35 121.0 0.3 7.3e-35 119.3 0.1 1.9 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EMC91145.1 - 7.6e-12 45.6 0.4 1.7e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 PIN like domain DUF4706 PF15797.5 EMC91145.1 - 0.028 14.9 0.1 0.15 12.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) Formyl_trans_N PF00551.19 EMC91147.1 - 5e-41 140.4 0.0 5.9e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Pro-kuma_activ PF09286.11 EMC91148.1 - 7.6e-39 133.2 0.0 3.4e-36 124.7 0.0 2.3 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMC91148.1 - 0.0046 16.3 0.2 0.0075 15.6 0.2 1.3 1 0 0 1 1 1 1 Subtilase family RPAP3_C PF13877.6 EMC91148.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Halogen_Hydrol PF10112.9 EMC91149.1 - 0.21 11.6 0.1 0.23 11.5 0.1 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Questin_oxidase PF14027.6 EMC91151.1 - 7.6e-98 328.2 0.1 9.8e-98 327.8 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like 4PPT_N PF17837.1 EMC91152.1 - 0.028 14.5 0.1 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain Lactamase_B_5 PF14597.6 EMC91152.1 - 0.058 12.9 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Proteasome PF00227.26 EMC91154.1 - 2.8e-46 157.4 1.1 1.7e-32 112.4 0.0 2.6 2 1 1 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 EMC91154.1 - 5.6e-12 45.1 1.0 6.3e-12 44.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_Tnp_IS1595 PF12760.7 EMC91155.1 - 0.94 9.5 4.1 0.44 10.5 0.6 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF3543 PF12063.8 EMC91157.1 - 1.3e-84 283.5 0.1 2.3e-84 282.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EMC91157.1 - 1.5e-59 201.5 0.0 2.6e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC91157.1 - 4.6e-39 134.3 0.0 7.7e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMC91157.1 - 0.021 13.6 0.0 0.062 12.1 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EMC91157.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pex2_Pex12 PF04757.14 EMC91158.1 - 9.4e-44 149.7 5.7 1.2e-43 149.4 5.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 EMC91158.1 - 5.2e-11 42.7 10.2 1e-10 41.7 10.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMC91158.1 - 1.7e-09 37.3 11.0 3e-09 36.6 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC91158.1 - 2.4e-09 36.9 8.3 3.9e-09 36.2 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMC91158.1 - 2.5e-09 36.8 7.0 3.9e-09 36.2 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC91158.1 - 8.6e-08 32.1 8.9 1.7e-07 31.1 8.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMC91158.1 - 6.8e-07 29.2 6.6 1.2e-06 28.4 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EMC91158.1 - 9.5e-07 29.0 8.7 1.9e-06 28.1 8.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EMC91158.1 - 8.5e-06 25.5 8.0 1.4e-05 24.8 8.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EMC91158.1 - 3e-05 24.1 9.2 5.2e-05 23.3 9.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EMC91158.1 - 0.0017 18.2 2.5 0.0034 17.2 2.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 EMC91158.1 - 0.0081 16.0 2.2 0.018 14.9 2.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 EMC91158.1 - 0.022 14.9 6.6 0.04 14.0 6.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EMC91158.1 - 0.022 14.8 7.0 0.042 13.9 7.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EMC91158.1 - 0.025 14.4 6.7 0.052 13.3 6.7 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EMC91158.1 - 0.079 12.7 2.5 0.17 11.7 2.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 EMC91158.1 - 0.52 10.4 5.9 0.9 9.6 5.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EMC91158.1 - 1.6 8.4 6.8 3.5 7.3 6.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 EMC91158.1 - 4.2 7.7 7.5 4.6 7.5 6.1 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain HAD PF12710.7 EMC91159.1 - 0.00034 21.1 0.2 0.27 11.6 0.1 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Fer2_3 PF13085.6 EMC91160.1 - 7.2e-32 109.6 0.0 1.1e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EMC91160.1 - 4.8e-09 36.6 6.4 4.8e-09 36.6 6.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMC91160.1 - 7.8e-08 32.7 7.8 7.8e-08 32.7 7.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMC91160.1 - 1.1e-06 28.6 3.8 1.1e-06 28.6 3.8 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EMC91160.1 - 0.009 15.9 0.3 0.009 15.9 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 EMC91160.1 - 0.015 15.9 5.6 0.015 15.9 5.6 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EMC91160.1 - 0.065 13.4 2.7 0.69 10.1 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 EMC91160.1 - 0.2 11.6 2.5 0.22 11.4 0.4 2.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain AA_permease PF00324.21 EMC91161.1 - 5.1e-114 381.5 37.8 6.2e-114 381.2 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMC91161.1 - 3e-34 118.6 38.1 4e-34 118.2 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.12 EMC91161.1 - 0.025 14.9 0.2 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) F-box-like PF12937.7 EMC91162.1 - 8.9e-08 31.9 0.6 2.4e-07 30.5 0.6 1.8 1 0 0 1 1 1 1 F-box-like TPR_1 PF00515.28 EMC91162.1 - 2.9e-07 30.0 4.9 0.00042 20.0 0.8 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC91162.1 - 8.4e-06 25.5 11.1 0.0061 16.6 0.3 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat LRR_8 PF13855.6 EMC91162.1 - 8.7e-06 25.4 3.4 0.00059 19.6 0.0 4.1 3 1 1 4 4 4 1 Leucine rich repeat TPR_11 PF13414.6 EMC91162.1 - 3.1e-05 23.6 1.5 0.0012 18.4 0.2 2.3 2 0 0 2 2 2 1 TPR repeat F-box PF00646.33 EMC91162.1 - 0.00046 20.0 1.2 0.0026 17.6 0.1 2.6 2 0 0 2 2 2 1 F-box domain TPR_16 PF13432.6 EMC91162.1 - 0.0074 16.9 2.4 0.022 15.4 2.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat LRR_6 PF13516.6 EMC91162.1 - 0.01 15.8 3.3 1.6 9.0 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 EMC91162.1 - 0.029 14.8 14.3 0.073 13.5 0.0 5.3 5 1 3 8 8 6 0 Leucine Rich repeats (2 copies) TPR_9 PF13371.6 EMC91162.1 - 0.038 14.1 2.3 0.15 12.3 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC91162.1 - 0.046 14.0 0.7 0.1 12.8 0.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EMC91162.1 - 0.11 12.8 8.0 3.7 7.9 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMC91162.1 - 0.18 12.7 7.8 9.2 7.4 0.3 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 EMC91163.1 - 3.9e-16 58.9 30.8 3.9e-16 58.9 30.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.32 EMC91165.1 - 3e-25 88.0 6.8 3.6e-06 27.6 0.2 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 EMC91165.1 - 0.01 14.5 2.5 0.034 12.8 0.1 2.8 1 1 3 4 4 4 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EMC91165.1 - 0.099 13.0 0.1 5.1 7.5 0.0 3.2 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RhoGAP PF00620.27 EMC91166.1 - 9.4e-17 61.2 0.0 2.1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 EMC91166.1 - 1.3e-10 41.2 0.0 2.5e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EMC91166.1 - 1.5e-09 38.0 0.0 3.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Syntaxin PF00804.25 EMC91166.1 - 0.093 12.4 0.3 0.41 10.3 0.1 2.1 2 0 0 2 2 2 0 Syntaxin YTH PF04146.15 EMC91167.1 - 2.3e-60 203.3 0.0 3.2e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 EMC91167.1 - 1.1e-05 25.2 0.0 3e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CotJB PF12652.7 EMC91168.1 - 0.13 12.5 0.1 0.51 10.6 0.0 1.8 2 0 0 2 2 2 0 CotJB protein PI3_PI4_kinase PF00454.27 EMC91169.1 - 1.4e-38 133.1 0.0 2.8e-36 125.6 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EMC91169.1 - 1.8e-25 89.5 0.0 4.4e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pyr_redox_2 PF07992.14 EMC91170.1 - 6.3e-46 156.9 0.0 7.8e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC91170.1 - 1.5e-12 47.9 0.0 1.4e-09 38.3 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC91170.1 - 4.7e-05 22.6 0.0 0.87 8.6 0.0 3.6 2 2 1 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.6 EMC91170.1 - 0.091 13.0 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain But2 PF09792.9 EMC91171.1 - 7.9e-45 152.7 1.5 1.9e-44 151.5 1.5 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_hydro_17 PF00332.18 EMC91171.1 - 9.4e-06 25.4 0.8 1.2e-05 25.1 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 zf-CSL PF05207.13 EMC91172.1 - 2.4e-19 68.8 0.4 3.6e-19 68.2 0.4 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EMC91172.1 - 7.7e-15 54.8 0.2 1.2e-14 54.2 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.6 EMC91173.1 - 4.5e-05 23.9 10.9 1.8 9.6 0.0 6.7 7 2 1 8 8 8 3 Tetratricopeptide repeat Suf PF05843.14 EMC91173.1 - 0.00014 22.0 7.4 0.0012 18.9 0.5 2.7 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EMC91173.1 - 0.0057 17.1 0.0 0.17 12.4 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat EF-hand_12 PF17901.1 EMC91173.1 - 0.068 13.6 0.5 0.068 13.6 0.5 2.0 2 1 0 2 2 2 0 EF-hand fold domain TPR_9 PF13371.6 EMC91173.1 - 0.65 10.2 4.6 20 5.4 0.9 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 EMC91174.1 - 2.8e-90 303.3 26.6 3.5e-90 303.1 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC91174.1 - 1.5e-29 103.0 37.0 1.8e-28 99.5 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMC91174.1 - 1.1e-07 30.6 4.2 1.1e-07 30.6 4.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EMC91174.1 - 0.003 16.5 16.7 0.046 12.6 6.7 2.4 2 1 0 2 2 2 2 MFS_1 like family UAF_Rrn10 PF05234.11 EMC91176.1 - 0.22 11.8 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 UAF complex subunit Rrn10 WD40 PF00400.32 EMC91177.1 - 4.6e-17 62.1 8.2 4.7e-07 30.4 0.7 5.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC91177.1 - 4e-10 39.9 0.0 0.016 15.5 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC91177.1 - 0.05 12.2 0.1 0.25 9.9 0.0 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 SRR1 PF07985.12 EMC91178.1 - 0.099 12.7 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 SRR1 Cupin_2 PF07883.11 EMC91179.1 - 1.8e-06 27.6 0.1 0.02 14.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 EMC91179.1 - 6.3e-06 25.9 0.1 9.7e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 EMC91179.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family Acetyltransf_1 PF00583.25 EMC91180.1 - 9.4e-05 22.6 0.0 0.00015 22.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC91180.1 - 0.00056 19.8 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC91180.1 - 0.00088 19.7 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GCD14 PF08704.10 EMC91181.1 - 1.3e-60 205.1 0.0 3.2e-60 203.9 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit APOBEC4 PF18775.1 EMC91181.1 - 0.051 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 APOBEC4 GST_N_3 PF13417.6 EMC91182.1 - 7.2e-11 42.3 0.0 1.9e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMC91182.1 - 4e-09 36.6 0.0 8.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMC91182.1 - 1.8e-05 24.8 0.0 2.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMC91182.1 - 0.00047 20.1 0.0 0.00077 19.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC91182.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMC91182.1 - 0.0062 17.1 0.0 0.013 16.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peroxin-22 PF12827.7 EMC91183.1 - 0.21 11.5 0.0 0.33 10.9 0.0 1.4 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family Hexapep PF00132.24 EMC91184.1 - 1.6e-08 33.9 9.1 8.9e-05 22.1 3.1 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EMC91184.1 - 0.00054 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 EMC91184.1 - 0.0033 15.6 3.0 0.25 9.5 0.8 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 EMC91184.1 - 0.031 13.8 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Fucokinase PF07959.12 EMC91184.1 - 0.27 10.1 0.2 0.4 9.6 0.2 1.2 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 EMC91184.1 - 0.4 10.5 10.9 0.098 12.4 2.1 3.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase WD40 PF00400.32 EMC91185.1 - 1.3e-17 63.8 13.5 0.00012 22.8 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC91185.1 - 1.1e-07 32.1 0.0 0.0025 18.1 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EMC91186.1 - 6.9e-13 48.2 0.0 3.7e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMC91186.1 - 5.1e-06 26.1 0.0 5.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Autophagy_act_C PF03987.15 EMC91187.1 - 1.6e-13 51.0 0.2 2.4e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain SKG6 PF08693.10 EMC91190.1 - 8.2e-06 25.1 0.4 1.7e-05 24.1 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 EMC91190.1 - 0.0026 17.6 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 EMC91190.1 - 0.0032 18.3 0.0 0.0068 17.3 0.0 1.6 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 EMC91190.1 - 0.045 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.9 EMC91190.1 - 0.066 12.0 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PNP_phzG_C PF10590.9 EMC91191.1 - 5e-22 77.7 3.7 1.6e-21 76.1 2.4 2.3 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EMC91191.1 - 2.1e-17 63.1 0.0 3.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EMC91191.1 - 0.00085 19.9 0.2 0.0015 19.1 0.2 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Zn_clus PF00172.18 EMC91193.1 - 5.1e-10 39.3 7.7 9e-10 38.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMC91193.1 - 3.4e-08 32.7 1.5 8.9e-08 31.3 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain MgsA_C PF12002.8 EMC91194.1 - 1.5e-56 190.9 0.2 2.5e-56 190.2 0.2 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EMC91194.1 - 1.9e-21 76.2 0.2 4.2e-21 75.1 0.2 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EMC91194.1 - 9.1e-15 55.3 0.0 2.4e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMC91194.1 - 5.6e-10 39.2 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EMC91194.1 - 3.1e-05 23.7 0.0 0.0008 19.2 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EMC91194.1 - 7.2e-05 22.8 0.2 0.0038 17.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC91194.1 - 0.00011 22.7 0.0 0.02 15.3 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 EMC91194.1 - 0.00011 22.0 0.0 0.00039 20.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EMC91194.1 - 0.00012 21.5 0.1 0.22 10.9 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EMC91194.1 - 0.00021 21.6 0.0 0.00054 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EMC91194.1 - 0.0021 18.2 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 EMC91194.1 - 0.003 17.6 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMC91194.1 - 0.0041 17.4 0.2 0.0079 16.5 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMC91194.1 - 0.012 15.3 0.2 0.029 14.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMC91194.1 - 0.015 15.7 0.5 0.046 14.1 0.4 1.7 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 EMC91194.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SKI PF01202.22 EMC91194.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase TIP49 PF06068.13 EMC91194.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ResIII PF04851.15 EMC91194.1 - 0.032 14.3 0.3 1.1 9.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 EMC91194.1 - 0.051 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EMC91194.1 - 0.063 13.0 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EMC91194.1 - 0.085 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EMC91194.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EMC91194.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain FKBP_C PF00254.28 EMC91195.1 - 1.4e-24 86.2 0.1 1.6e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.19 EMC91196.1 - 3.1e-14 53.6 0.1 4.3e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 PHP domain Pkinase PF00069.25 EMC91197.1 - 4.1e-72 242.7 0.0 5.3e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC91197.1 - 5.1e-35 121.0 0.0 6.6e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EMC91197.1 - 2.6e-15 56.5 0.2 4.8e-15 55.7 0.2 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EMC91197.1 - 1.3e-11 44.4 0.0 4.7e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMC91197.1 - 2.4e-06 26.6 0.0 4.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EMC91197.1 - 7.5e-06 26.2 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 EMC91197.1 - 0.0091 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 EMC91197.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EMC91197.1 - 0.039 12.9 0.1 0.058 12.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Acyl-CoA_dh_N PF02771.16 EMC91198.1 - 6.6e-18 65.4 0.0 1.8e-17 64.0 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EMC91198.1 - 0.00052 20.2 0.0 0.00086 19.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain p450 PF00067.22 EMC91199.1 - 7.5e-73 245.8 0.0 9.1e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.21 EMC91200.1 - 1.1e-11 44.7 0.0 1.9e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase CMD PF02627.20 EMC91201.1 - 1.2e-08 34.9 0.2 2.5e-08 33.9 0.3 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Beta-prism_lec PF16458.5 EMC91201.1 - 0.079 12.9 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 Beta-prism lectin NIT PF08376.10 EMC91202.1 - 0.00043 20.8 2.4 0.087 13.3 0.0 2.4 2 0 0 2 2 2 2 Nitrate and nitrite sensing PAPA-1 PF04795.12 EMC91204.1 - 1.9e-08 35.0 7.0 1.9e-08 35.0 7.0 3.0 2 1 0 2 2 2 1 PAPA-1-like conserved region YL1 PF05764.13 EMC91204.1 - 4.7 7.3 34.9 0.61 10.2 18.0 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Pex14_N PF04695.13 EMC91205.1 - 2.6e-24 86.6 4.7 2.6e-24 86.6 4.7 3.5 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region NleF_casp_inhib PF16809.5 EMC91205.1 - 0.032 14.1 0.4 11 5.9 0.1 2.9 3 0 0 3 3 3 0 NleF caspase inhibitor UPF0086 PF01868.16 EMC91206.1 - 2.2e-29 101.2 0.2 3.6e-29 100.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 M16C_assoc PF08367.11 EMC91208.1 - 1.6e-75 253.5 0.0 3.4e-75 252.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EMC91208.1 - 9.8e-33 113.7 0.0 8.4e-23 81.3 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMC91208.1 - 5e-09 36.3 0.0 1.8e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF1387 PF07139.11 EMC91208.1 - 0.074 12.8 0.5 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Taxilin PF09728.9 EMC91209.1 - 4e-82 275.9 60.2 4e-82 275.9 60.2 1.5 2 0 0 2 2 2 1 Myosin-like coiled-coil protein zf-C4H2 PF10146.9 EMC91209.1 - 0.0058 17.0 3.8 0.0058 17.0 3.8 3.3 2 1 1 3 3 3 1 Zinc finger-containing protein ATG16 PF08614.11 EMC91209.1 - 0.0063 16.8 11.5 0.0063 16.8 11.5 3.5 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Abhydrolase_1 PF00561.20 EMC91210.1 - 2.6e-06 27.3 0.0 7.2e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC91210.1 - 2.9e-06 26.7 0.0 0.00012 21.4 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 EMC91210.1 - 4.2e-06 26.5 0.0 5.8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EMC91210.1 - 2.9e-05 23.7 0.0 0.036 13.5 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EMC91210.1 - 4.8e-05 24.1 0.1 0.00015 22.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.11 EMC91210.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF1749 PF08538.10 EMC91210.1 - 0.019 14.0 0.0 0.056 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) BAAT_C PF08840.11 EMC91210.1 - 0.037 13.9 0.0 0.061 13.2 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LCAT PF02450.15 EMC91210.1 - 0.061 12.5 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pilus_CpaD PF09476.10 EMC91210.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) eRF1_1 PF03463.15 EMC91210.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 1 DEAD PF00270.29 EMC91211.1 - 1.6e-48 164.8 0.0 4e-48 163.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC91211.1 - 4.8e-32 110.6 0.0 1.3e-31 109.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC91211.1 - 0.0004 20.4 0.0 0.00073 19.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EMC91211.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 EMC91211.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Mnd1 PF03962.15 EMC91213.1 - 1.5e-23 82.8 0.1 3.2e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain Macoilin PF09726.9 EMC91213.1 - 9.6e-05 21.1 1.8 0.00012 20.8 1.8 1.0 1 0 0 1 1 1 1 Macoilin family TFIIE_beta PF02186.15 EMC91213.1 - 0.039 14.2 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 TFIIE beta subunit core domain Spc7 PF08317.11 EMC91213.1 - 0.21 10.4 5.6 0.65 8.8 1.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Cnn_1N PF07989.11 EMC91213.1 - 0.23 11.6 4.4 0.085 13.0 1.0 2.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 AMP-binding PF00501.28 EMC91214.1 - 2.1e-67 227.6 0.0 2.7e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC91214.1 - 8.2e-06 26.7 0.0 1.6e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 EMC91215.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EMC91215.1 - 0.0023 18.4 0.1 0.0058 17.1 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EMC91215.1 - 0.0064 16.1 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Pepsin-I3 PF06394.13 EMC91215.1 - 0.021 15.0 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain hDGE_amylase PF14701.6 EMC91216.1 - 3.6e-178 593.2 0.0 4.7e-178 592.8 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EMC91216.1 - 3.5e-116 388.3 0.0 5.6e-116 387.6 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EMC91216.1 - 1.5e-84 283.6 0.0 2.5e-84 282.9 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EMC91216.1 - 2.4e-30 104.5 0.1 7.9e-30 102.8 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 EMC91216.1 - 0.02 14.5 0.1 0.048 13.2 0.1 1.6 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Peptidase_M16_C PF05193.21 EMC91218.1 - 2e-26 93.1 0.0 3.4e-22 79.3 0.0 3.4 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMC91218.1 - 9e-08 32.2 0.1 3.1e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Ribosomal_S13 PF00416.22 EMC91220.1 - 2.3e-18 66.8 0.5 5.8e-16 59.1 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.21 EMC91221.1 - 1.2e-49 168.7 0.4 1.5e-49 168.3 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short PF00106.25 EMC91222.1 - 3.3e-32 111.5 0.0 4.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC91222.1 - 8.4e-19 68.1 0.0 1.2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC91222.1 - 1.9e-05 24.7 0.0 3.9e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMC91222.1 - 0.017 14.5 0.0 0.13 11.7 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EMC91222.1 - 0.09 12.3 0.1 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family DAP3 PF10236.9 EMC91223.1 - 2.1e-87 293.2 0.0 2.6e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 TsaE PF02367.17 EMC91223.1 - 0.012 15.6 0.2 5.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EMC91223.1 - 0.041 14.3 0.2 0.11 12.8 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain LRR_8 PF13855.6 EMC91224.1 - 1.1e-09 38.0 3.0 1.1e-09 38.0 3.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EMC91224.1 - 1e-05 25.7 9.0 0.00029 21.2 1.0 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMC91224.1 - 0.02 15.4 3.8 7.2 7.6 0.1 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat DnaJ PF00226.31 EMC91225.1 - 3.2e-19 68.8 3.2 3.2e-19 68.8 3.2 1.5 2 0 0 2 2 2 1 DnaJ domain Bacteriocin_IIc PF10439.9 EMC91225.1 - 0.0044 17.1 2.4 0.0082 16.2 2.4 1.4 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide TPR_19 PF14559.6 EMC91226.1 - 1.2e-07 32.1 2.1 2e-07 31.4 0.1 2.5 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMC91226.1 - 0.00011 22.0 0.4 0.00044 20.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EMC91226.1 - 0.00013 22.1 0.7 0.00086 19.4 0.5 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMC91226.1 - 0.00028 21.4 4.0 0.027 15.3 0.7 4.2 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EMC91226.1 - 0.0011 19.2 0.3 0.023 15.0 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMC91226.1 - 0.0011 18.9 1.2 0.0098 15.9 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMC91226.1 - 0.0012 18.5 0.0 0.096 12.4 0.0 3.6 3 2 1 4 4 4 1 TPR repeat TPR_1 PF00515.28 EMC91226.1 - 0.002 17.9 1.0 0.0072 16.1 0.1 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMC91226.1 - 0.0033 17.7 0.2 0.038 14.4 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC91226.1 - 0.0084 16.3 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EMC91226.1 - 0.017 15.3 1.2 0.035 14.3 0.0 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMC91226.1 - 0.022 15.1 0.6 1 9.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 EMC91226.1 - 0.039 13.0 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) DpnII PF04556.12 EMC91226.1 - 0.049 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 DpnII restriction endonuclease DUF5113 PF17140.4 EMC91226.1 - 0.071 12.9 0.2 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) TPR_16 PF13432.6 EMC91226.1 - 0.17 12.5 4.8 0.27 11.9 0.5 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Adaptin_N PF01602.20 EMC91227.1 - 7.3e-83 278.9 0.0 1.4e-82 278.0 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EMC91227.1 - 2.2e-07 31.1 0.0 8.4e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EMC91227.1 - 0.019 15.2 0.1 14 6.3 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 EMC91227.1 - 0.069 13.7 2.8 32 5.2 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 EMC91227.1 - 0.14 12.6 10.2 2.5 8.5 0.0 4.5 4 1 0 4 4 4 0 HEAT repeats Fungal_trans_2 PF11951.8 EMC91229.1 - 5.6e-84 282.2 0.0 7.3e-84 281.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC91229.1 - 1.8e-06 28.0 9.0 3.9e-06 26.9 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.23 EMC91230.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SAM_2 PF07647.17 EMC91231.1 - 1.2e-08 34.9 0.2 2.2e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EMC91231.1 - 1.3e-06 28.7 0.3 4e-06 27.2 0.3 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 EMC91231.1 - 1.1e-05 25.9 0.0 2.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EMC91231.1 - 0.085 13.3 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain SAM_3 PF18016.1 EMC91231.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) WBS_methylT PF12589.8 EMC91232.1 - 1.2e-13 51.6 5.9 2.3e-13 50.7 5.9 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EMC91232.1 - 1.6e-11 44.7 0.0 3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC91232.1 - 3.6e-10 40.4 0.0 8.9e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC91232.1 - 1.6e-05 25.5 0.0 5.1e-05 24.0 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EMC91232.1 - 3.7e-05 23.6 0.0 7.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EMC91232.1 - 0.0018 18.0 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC91232.1 - 0.0065 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMC91232.1 - 0.0097 15.2 0.0 0.034 13.5 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EMC91232.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EMC91232.1 - 0.029 14.4 0.1 0.063 13.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EMC91232.1 - 0.059 12.9 1.2 4.7 6.7 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_33 PF10017.9 EMC91232.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF3724 PF12521.8 EMC91232.1 - 0.13 12.2 0.1 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) MetW PF07021.12 EMC91232.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Erv26 PF04148.13 EMC91233.1 - 4.6e-93 310.7 0.1 5.3e-93 310.6 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 PhoR PF11808.8 EMC91233.1 - 10 6.6 13.9 27 5.3 0.0 3.5 4 0 0 4 4 4 0 Phosphate regulon sensor protein PhoR Perm-CXXC PF15629.6 EMC91234.1 - 1.7 8.9 20.8 41 4.6 0.0 7.9 8 0 0 8 8 8 0 Permuted single zf-CXXC unit DUF2306 PF10067.9 EMC91235.1 - 0.054 13.7 1.7 0.086 13.0 1.7 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2306) Peptidase_C48 PF02902.19 EMC91237.1 - 4.8e-16 59.2 0.2 3.5e-15 56.4 0.2 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 EMC91237.1 - 0.03 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) Iso_dh PF00180.20 EMC91238.1 - 2.1e-85 287.0 0.0 2.6e-85 286.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DSBA PF01323.20 EMC91239.1 - 3.4e-14 53.1 0.0 3.8e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain UCH PF00443.29 EMC91240.1 - 1.8e-26 93.2 0.0 2.6e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EMC91240.1 - 8e-09 35.7 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EMC91240.1 - 0.046 13.3 0.1 0.096 12.3 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Goodbye PF17109.5 EMC91241.1 - 3.7e-21 75.8 0.1 2.7e-20 73.0 0.0 2.5 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EMC91241.1 - 0.022 14.7 2.3 0.15 11.9 0.0 3.1 2 1 1 3 3 3 0 NACHT domain AAA_25 PF13481.6 EMC91241.1 - 0.031 13.8 0.1 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMC91241.1 - 0.045 14.1 2.1 0.094 13.1 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EMC91241.1 - 0.17 12.2 0.2 2.2 8.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF5327 PF17261.2 EMC91241.1 - 3 8.6 8.5 0.55 11.0 3.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) TPR_14 PF13428.6 EMC91242.1 - 4.7e-05 23.9 4.0 4.2 8.4 0.0 5.0 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMC91242.1 - 0.00022 21.8 0.5 0.95 10.2 0.0 4.5 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMC91242.1 - 0.0017 18.8 0.4 0.44 11.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMC91242.1 - 0.0047 16.9 7.2 0.025 14.6 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMC91242.1 - 0.025 14.7 5.1 10 6.5 0.2 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4363 PF14276.6 EMC91242.1 - 0.11 12.6 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) TPR_10 PF13374.6 EMC91242.1 - 0.35 10.8 6.2 2.5 8.1 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMC91242.1 - 0.49 10.3 2.5 9.2 6.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5502 PF17606.2 EMC91244.1 - 0.07 13.8 0.0 0.11 13.3 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5502) Aldo_ket_red PF00248.21 EMC91245.1 - 1.3e-43 149.3 0.0 4e-30 105.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family P3A PF08727.11 EMC91245.1 - 2.7e-05 23.5 0.1 0.0065 15.8 0.1 2.3 2 0 0 2 2 2 2 Poliovirus 3A protein like IF-2B PF01008.17 EMC91246.1 - 9.8e-76 254.6 0.4 1.3e-75 254.3 0.4 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family AIG2_2 PF13772.6 EMC91247.1 - 9e-06 26.0 0.5 8e-05 23.0 0.5 2.1 1 1 0 1 1 1 1 AIG2-like family GATA-N PF05349.12 EMC91247.1 - 0.03 14.6 0.5 0.12 12.7 0.4 1.9 1 1 1 2 2 2 0 GATA-type transcription activator, N-terminal OTT_1508_deam PF14441.6 EMC91249.1 - 7.2e-14 51.5 1.1 1.9e-13 50.2 1.1 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase EF-hand_4 PF12763.7 EMC91250.1 - 2.7e-25 88.3 0.0 1.7e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 EMC91250.1 - 4.3e-06 26.4 0.7 4.3e-06 26.4 0.7 3.1 3 0 0 3 3 3 1 WH2 motif DUF1720 PF08226.11 EMC91250.1 - 9.8e-06 25.9 184.6 0.00074 19.9 49.9 8.5 6 2 1 8 8 8 4 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 EMC91250.1 - 0.00024 20.4 0.0 0.084 12.5 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EMC91250.1 - 0.00033 21.1 0.8 0.23 11.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EMC91250.1 - 0.028 14.3 0.2 49 4.2 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain EF-hand_8 PF13833.6 EMC91250.1 - 0.14 12.0 0.1 2.5 8.0 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair HCNGP PF07818.13 EMC91251.1 - 3.7e-19 69.2 0.0 7.6e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 HCNGP-like protein K_channel_TID PF07941.11 EMC91251.1 - 5.1 7.6 7.0 0.49 10.9 1.6 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Proteasome PF00227.26 EMC91252.1 - 1.2e-28 99.9 0.0 1.4e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit eIF3_subunit PF08597.10 EMC91253.1 - 1.6e-70 237.7 20.9 2e-70 237.5 20.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit p450 PF00067.22 EMC91253.1 - 0.065 12.0 0.0 0.065 12.0 0.0 1.6 2 0 0 2 2 2 0 Cytochrome P450 Rrn6 PF10214.9 EMC91253.1 - 0.15 10.5 5.1 0.18 10.3 5.1 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Folliculin PF11704.8 EMC91253.1 - 5.1 6.9 8.0 5.5 6.8 0.9 2.4 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Clathrin PF00637.20 EMC91254.1 - 4.7e-200 655.5 26.3 8.9e-32 109.9 0.1 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EMC91254.1 - 1.7e-32 111.1 4.0 5.9e-32 109.4 1.8 3.1 2 1 1 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 EMC91254.1 - 1.6e-30 103.9 0.8 7.8e-09 35.4 0.0 6.8 7 0 0 7 7 6 4 Clathrin propeller repeat Vps39_1 PF10366.9 EMC91254.1 - 2.7e-05 24.4 5.7 2.9 8.2 0.0 6.1 5 1 1 6 6 5 1 Vacuolar sorting protein 39 domain 1 Clathrin-link PF09268.10 EMC91254.1 - 0.00083 18.7 0.1 0.0022 17.3 0.1 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_14 PF13428.6 EMC91254.1 - 0.0029 18.3 21.8 2.2 9.3 0.1 9.9 11 0 0 11 11 9 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EMC91254.1 - 0.0055 15.8 3.1 0.11 11.5 0.2 3.6 4 0 0 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.6 EMC91254.1 - 0.015 15.3 8.3 12 6.1 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMC91254.1 - 0.23 11.9 4.5 44 4.8 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMC91254.1 - 0.47 10.8 0.0 0.47 10.8 0.0 5.7 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMC91254.1 - 0.92 9.8 0.0 0.92 9.8 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMC91254.1 - 5.5 7.0 9.3 3.8 7.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat HhH-GPD PF00730.25 EMC91255.1 - 9.5e-07 29.2 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein WD40 PF00400.32 EMC91256.1 - 7.4e-50 165.9 17.6 1.1e-05 26.1 0.0 13.7 12 3 0 12 12 12 8 WD domain, G-beta repeat Utp13 PF08625.11 EMC91256.1 - 3.2e-48 163.2 1.5 5.2e-48 162.6 1.5 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EMC91256.1 - 2.3e-11 43.9 3.3 1 9.7 0.0 7.5 6 2 2 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC91256.1 - 5e-07 28.7 9.9 0.29 9.7 0.0 5.9 5 2 2 7 7 7 4 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EMC91256.1 - 0.016 14.2 2.3 0.091 11.7 0.1 3.0 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EMC91256.1 - 0.025 13.6 0.3 10 5.0 0.0 4.0 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EMC91256.1 - 0.031 13.0 3.7 8.3 5.0 0.0 4.4 6 1 1 7 7 7 0 Nup133 N terminal like Proteasome PF00227.26 EMC91257.1 - 3.7e-36 124.4 0.0 4.2e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit cobW PF02492.19 EMC91259.1 - 6.5e-36 123.6 0.1 9.2e-36 123.1 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EMC91259.1 - 2.8e-06 27.2 0.0 2.8e-06 27.2 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 EMC91259.1 - 0.00019 21.1 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EMC91259.1 - 0.00047 20.6 0.0 0.00089 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 EMC91259.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EMC91259.1 - 0.0018 18.6 0.2 0.0071 16.6 0.1 2.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EMC91259.1 - 0.0048 16.2 0.0 0.0095 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EMC91259.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 EMC91259.1 - 0.024 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 NTPase_1 PF03266.15 EMC91259.1 - 0.066 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 NTPase TrwB_AAD_bind PF10412.9 EMC91259.1 - 0.083 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.23 EMC91259.1 - 0.085 12.9 0.0 0.18 11.9 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EMC91259.1 - 0.12 12.9 0.1 0.34 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 EMC91259.1 - 0.12 12.1 0.4 0.35 10.6 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EMC91259.1 - 0.13 11.4 0.0 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain CobW_C PF07683.14 EMC91259.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain TPR_19 PF14559.6 EMC91259.1 - 0.19 12.3 0.6 1.4 9.4 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_11 PF13086.6 EMC91259.1 - 0.44 10.3 1.9 3.9 7.2 0.0 2.7 2 1 1 3 3 3 0 AAA domain Lipocalin_5 PF13924.6 EMC91260.1 - 5e-22 78.2 0.0 5.6e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Peptidase_U4 PF03419.13 EMC91261.1 - 4.1 6.6 9.1 1.9 7.7 1.2 2.2 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Lipase_3 PF01764.25 EMC91262.1 - 9.9e-28 96.8 0.0 1.4e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EMC91262.1 - 7.8e-05 23.4 0.2 0.0001 23.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3463 PF11946.8 EMC91262.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) Hydrolase_4 PF12146.8 EMC91262.1 - 0.16 11.2 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2026 PF09641.10 EMC91263.1 - 0.017 14.8 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) HTH_28 PF13518.6 EMC91263.1 - 0.58 10.3 4.2 1.3 9.2 4.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain RRS1 PF04939.12 EMC91266.1 - 5e-50 169.5 1.6 5.6e-50 169.4 1.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) LOR PF04525.12 EMC91267.1 - 2.2e-21 76.3 0.1 2.8e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 LURP-one-related Acyl-CoA_ox_N PF14749.6 EMC91270.1 - 0.021 15.4 0.1 0.037 14.6 0.1 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal ATP11 PF06644.11 EMC91271.1 - 3.2e-100 335.4 0.3 3.7e-100 335.2 0.3 1.0 1 0 0 1 1 1 1 ATP11 protein DUF4119 PF13494.6 EMC91271.1 - 0.027 14.6 0.0 0.081 13.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF3546 PF12066.8 EMC91271.1 - 0.39 10.9 4.7 0.21 11.8 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) AMP-binding PF00501.28 EMC91272.1 - 3.4e-105 352.1 0.0 4e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC91272.1 - 8.9e-17 61.8 1.7 1e-16 61.7 0.3 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NMO PF03060.15 EMC91273.1 - 2.4e-49 168.5 1.0 3.6e-49 167.9 1.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 EMC91273.1 - 5.2e-05 22.4 3.0 8e-05 21.8 3.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMC91273.1 - 0.00012 21.2 2.2 0.00061 18.9 2.2 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PEP_hydrolase PF09370.10 EMC91273.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like FAD_binding_3 PF01494.19 EMC91274.1 - 1.2e-16 60.9 0.1 1.2e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMC91274.1 - 0.00092 19.4 0.1 0.0023 18.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF1749 PF08538.10 EMC91275.1 - 5.2e-77 258.9 0.0 5.9e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EMC91275.1 - 5e-08 32.5 0.0 1.9e-07 30.6 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMC91275.1 - 1.9e-05 25.4 0.2 2.4e-05 25.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 EMC91275.1 - 0.00074 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 EMC91275.1 - 0.0037 17.2 0.1 0.0066 16.3 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase Cutinase PF01083.22 EMC91275.1 - 0.029 14.3 0.1 0.045 13.7 0.1 1.3 1 0 0 1 1 1 0 Cutinase Chlorophyllase2 PF12740.7 EMC91275.1 - 0.043 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EMC91275.1 - 0.14 11.7 0.0 0.44 10.2 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold EthD PF07110.11 EMC91276.1 - 0.04 15.1 0.0 0.33 12.1 0.1 2.2 2 0 0 2 2 2 0 EthD domain C2 PF00168.30 EMC91277.1 - 1.2e-15 57.6 0.0 2.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 EMC91278.1 - 8.6e-23 80.6 0.0 7.5e-11 42.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain COX8 PF02285.15 EMC91278.1 - 0.16 11.9 0.3 0.35 10.8 0.3 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII EMC3_TMCO1 PF01956.16 EMC91278.1 - 0.63 9.7 2.9 0.79 9.4 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Med7 PF05983.11 EMC91279.1 - 0.00053 20.1 0.1 0.00091 19.4 0.1 1.3 1 0 0 1 1 1 1 MED7 protein DUF5490 PF17593.2 EMC91279.1 - 0.13 12.3 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5490) Zn_clus PF00172.18 EMC91279.1 - 1.7 8.8 7.1 5.8 7.1 7.1 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mitoc_mL59 PF18126.1 EMC91280.1 - 2.6e-44 150.6 1.9 3.3e-44 150.3 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 zf-LYAR PF08790.11 EMC91281.1 - 2.7e-14 52.8 3.6 2.7e-14 52.8 3.6 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Glyco_hydro_3_C PF01915.22 EMC91282.1 - 4.5e-43 147.6 0.0 8.5e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMC91282.1 - 6.8e-36 124.2 0.0 1.1e-35 123.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMC91282.1 - 7.8e-20 70.8 0.1 1.5e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ABM PF03992.16 EMC91283.1 - 2.8e-07 30.6 0.0 3.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Aa_trans PF01490.18 EMC91284.1 - 8.8e-84 281.6 36.5 1e-83 281.4 36.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EMC91284.1 - 0.0015 17.6 17.1 0.0015 17.6 17.1 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family EIAV_Rev PF11129.8 EMC91284.1 - 0.026 14.7 0.2 0.053 13.7 0.2 1.5 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus GFA PF04828.14 EMC91285.1 - 2.3e-20 72.7 0.6 2.3e-20 72.7 0.6 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Securin PF04856.13 EMC91286.1 - 0.005 16.8 0.0 0.061 13.3 0.0 2.4 1 1 0 1 1 1 1 Securin sister-chromatid separation inhibitor HrpB7 PF09486.10 EMC91286.1 - 9 6.7 18.9 0.33 11.3 0.9 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Tropomyosin_1 PF12718.7 EMC91287.1 - 1.9e-51 174.0 31.3 2.2e-51 173.8 31.3 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EMC91287.1 - 2.5e-08 33.6 29.0 1.3e-05 24.7 4.4 2.8 1 1 0 2 2 2 2 Tropomyosin ADIP PF11559.8 EMC91287.1 - 0.0013 18.8 26.9 0.03 14.4 12.0 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 EMC91287.1 - 0.0032 17.5 30.5 0.11 12.6 17.8 2.6 1 1 2 3 3 3 2 BRE1 E3 ubiquitin ligase ERM PF00769.19 EMC91287.1 - 0.0045 16.8 31.6 0.011 15.6 9.5 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 EMC91287.1 - 0.0046 17.0 27.8 0.0056 16.7 1.6 3.0 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 EMC91287.1 - 0.0046 17.0 5.2 0.0046 17.0 5.2 2.2 1 1 1 2 2 2 1 Laminin Domain II DUF1664 PF07889.12 EMC91287.1 - 0.0058 16.7 16.7 0.019 15.0 2.9 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EMC91287.1 - 0.0073 15.6 25.8 0.24 10.7 9.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 EMC91287.1 - 0.0083 16.6 10.2 1.9 9.0 0.2 3.3 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein HOOK PF05622.12 EMC91287.1 - 0.0085 14.3 25.0 0.013 13.7 25.0 1.3 1 0 0 1 1 1 1 HOOK protein bZIP_1 PF00170.21 EMC91287.1 - 0.0087 16.1 25.1 0.54 10.4 2.1 4.8 3 1 2 5 5 5 1 bZIP transcription factor TMF_DNA_bd PF12329.8 EMC91287.1 - 0.009 16.0 31.0 0.015 15.3 13.0 3.2 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding HMMR_N PF15905.5 EMC91287.1 - 0.0095 15.4 25.8 0.013 15.0 25.8 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal KLRAQ PF10205.9 EMC91287.1 - 0.011 15.9 21.6 0.073 13.3 11.3 2.8 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein ATG16 PF08614.11 EMC91287.1 - 0.016 15.4 27.3 0.82 9.9 9.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 EMC91287.1 - 0.017 15.5 1.3 0.017 15.5 1.3 3.7 1 1 2 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TACC_C PF05010.14 EMC91287.1 - 0.021 14.6 23.7 0.6 9.9 18.1 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 EMC91287.1 - 0.023 14.0 28.8 0.15 11.4 27.6 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 EMC91287.1 - 0.026 14.9 32.3 0.037 14.4 11.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 EMC91287.1 - 0.027 13.4 29.4 0.14 11.0 16.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 EMC91287.1 - 0.031 14.5 23.6 1.3 9.3 17.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 EMC91287.1 - 0.036 14.5 20.0 0.7 10.3 7.2 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) HMMR_C PF15908.5 EMC91287.1 - 0.042 14.1 1.8 0.042 14.1 1.8 2.5 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal APG6_N PF17675.1 EMC91287.1 - 0.051 14.1 32.8 0.39 11.2 13.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DHR10 PF18595.1 EMC91287.1 - 0.055 13.5 31.1 0.18 11.9 8.9 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4201 PF13870.6 EMC91287.1 - 0.059 13.1 23.9 0.14 11.9 23.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) UPF0242 PF06785.11 EMC91287.1 - 0.067 13.3 28.7 0.14 12.2 10.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 EMC91287.1 - 0.07 13.0 24.7 0.92 9.3 9.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EzrA PF06160.12 EMC91287.1 - 0.087 11.0 22.8 0.12 10.6 5.5 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Taxilin PF09728.9 EMC91287.1 - 0.088 12.0 27.6 0.49 9.5 27.6 2.1 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Cast PF10174.9 EMC91287.1 - 0.097 10.9 22.9 0.12 10.6 22.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HrpB7 PF09486.10 EMC91287.1 - 0.12 12.8 17.1 0.17 12.3 17.1 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Filament PF00038.21 EMC91287.1 - 0.12 11.9 25.1 0.79 9.2 8.1 2.0 1 1 1 2 2 2 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 EMC91287.1 - 0.14 12.4 28.2 0.68 10.1 16.6 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 EMC91287.1 - 0.2 12.0 23.8 0.46 10.8 3.6 3.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MAD PF05557.13 EMC91287.1 - 0.21 9.9 27.1 0.24 9.7 27.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein CENP-H PF05837.12 EMC91287.1 - 0.27 11.7 24.7 1.4 9.4 12.2 2.7 1 1 2 3 3 3 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 EMC91287.1 - 0.29 11.2 32.4 1.7 8.7 11.8 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EMC91287.1 - 0.3 11.7 17.4 1.3 9.7 5.3 3.5 1 1 2 3 3 3 0 SlyX HAP1_N PF04849.13 EMC91287.1 - 0.33 10.1 24.8 1 8.5 24.8 1.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Seryl_tRNA_N PF02403.22 EMC91287.1 - 0.45 10.8 24.5 1.5 9.1 0.2 3.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.6 EMC91287.1 - 0.48 10.0 28.1 2.9 7.5 8.0 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease VGPC1_C PF16799.5 EMC91287.1 - 0.49 10.4 15.3 0.82 9.7 7.0 3.8 3 1 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF5595 PF18077.1 EMC91287.1 - 0.57 10.3 19.9 0.43 10.7 7.5 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5595) DUF2203 PF09969.9 EMC91287.1 - 0.62 10.8 17.2 0.52 11.0 3.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2730 PF10805.8 EMC91287.1 - 0.64 10.1 13.1 0.47 10.6 4.4 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) FH2 PF02181.23 EMC91287.1 - 0.83 8.7 18.7 0.38 9.8 3.9 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain Fmp27_WPPW PF10359.9 EMC91287.1 - 0.86 8.4 23.9 0.65 8.8 11.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TRAF_BIRC3_bd PF16673.5 EMC91287.1 - 0.87 9.4 17.4 1.4 8.8 2.0 3.7 1 1 3 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Nup88 PF10168.9 EMC91287.1 - 0.9 7.3 19.2 1.1 7.0 19.2 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF812 PF05667.11 EMC91287.1 - 0.9 8.3 29.0 0.68 8.8 12.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) SOGA PF11365.8 EMC91287.1 - 0.95 10.6 20.6 4.9 8.3 5.3 3.1 1 1 2 3 3 3 0 Protein SOGA Alanine_zipper PF11839.8 EMC91287.1 - 1 9.8 10.8 0.53 10.7 1.5 3.4 1 1 3 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein KASH_CCD PF14662.6 EMC91287.1 - 1.1 9.1 27.7 0.63 9.8 7.5 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4200 PF13863.6 EMC91287.1 - 1.1 9.7 30.5 1.3 9.5 16.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) T3SSipB PF16535.5 EMC91287.1 - 1.1 9.7 19.4 1.6 9.2 8.4 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB LPP PF04728.13 EMC91287.1 - 1.2 9.6 12.3 34 4.9 0.2 4.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper FPP PF05911.11 EMC91287.1 - 1.6 6.9 25.2 22 3.0 25.2 1.9 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 EMC91287.1 - 1.6 9.2 25.0 5.7 7.3 25.1 1.7 1 1 0 1 1 1 0 Fez1 OmpH PF03938.14 EMC91287.1 - 1.6 9.1 28.6 5.3 7.4 14.5 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 EMC91287.1 - 1.9 8.6 18.0 1.2 9.3 4.1 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 EMC91287.1 - 2.1 8.3 30.2 1.6 8.7 4.4 3.5 1 1 1 2 2 1 0 Axonemal dynein light chain Dynamitin PF04912.14 EMC91287.1 - 2.1 7.6 22.8 4.7 6.4 21.9 1.9 1 1 0 1 1 1 0 Dynamitin DUF3584 PF12128.8 EMC91287.1 - 2.1 5.8 23.3 2.8 5.3 23.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mod_r PF07200.13 EMC91287.1 - 2.2 8.4 24.2 0.35 11.0 10.0 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BST2 PF16716.5 EMC91287.1 - 2.4 8.8 23.2 0.45 11.1 4.7 3.4 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Cep57_CLD_2 PF14197.6 EMC91287.1 - 2.4 8.3 22.1 0.33 11.1 1.0 4.3 2 2 0 3 3 3 0 Centrosome localisation domain of PPC89 KELK PF15796.5 EMC91287.1 - 2.5 8.6 29.3 0.35 11.4 2.3 3.9 2 2 2 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Vps5 PF09325.10 EMC91287.1 - 3.1 7.3 22.2 0.12 11.9 6.8 2.9 1 1 2 3 3 3 0 Vps5 C terminal like IFT46_B_C PF12317.8 EMC91287.1 - 3.3 7.4 13.2 0.2 11.4 5.0 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Leu_zip PF15294.6 EMC91287.1 - 3.6 7.0 23.6 8.2 5.9 23.3 1.5 1 1 0 1 1 1 0 Leucine zipper Uds1 PF15456.6 EMC91287.1 - 3.8 7.7 22.5 20 5.3 3.6 3.2 1 1 1 2 2 2 0 Up-regulated During Septation bZIP_2 PF07716.15 EMC91287.1 - 3.8 7.7 30.5 1.3 9.1 3.6 5.1 2 2 3 5 5 5 0 Basic region leucine zipper ZapB PF06005.12 EMC91287.1 - 4.3 7.8 32.3 15 6.1 5.5 3.9 1 1 1 2 2 1 0 Cell division protein ZapB DUF4407 PF14362.6 EMC91287.1 - 4.3 6.6 21.2 9.1 5.5 21.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Rootletin PF15035.6 EMC91287.1 - 4.4 7.3 26.3 60 3.6 26.4 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMCO5 PF14992.6 EMC91287.1 - 4.6 6.7 24.4 12 5.4 24.4 1.6 1 1 0 1 1 1 0 TMCO5 family YabA PF06156.13 EMC91287.1 - 4.6 7.9 22.4 1.2e+04 -3.0 22.7 2.9 1 1 0 1 1 0 0 Initiation control protein YabA Lectin_N PF03954.14 EMC91287.1 - 4.8 6.9 12.9 1.6 8.4 2.2 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 EMC91287.1 - 5.1 6.2 21.2 0.61 9.3 9.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein Atg14 PF10186.9 EMC91287.1 - 5.7 5.9 23.2 0.39 9.8 9.1 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5320 PF17253.2 EMC91287.1 - 6 8.0 17.0 1.6 9.9 1.1 3.1 2 1 1 3 3 2 0 Family of unknown function (DUF5320) HemX PF04375.14 EMC91287.1 - 6.2 6.0 21.8 11 5.2 9.6 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF948 PF06103.11 EMC91287.1 - 6.6 7.1 12.3 4.5 7.6 1.8 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Swi5 PF07061.11 EMC91287.1 - 6.8 6.8 25.1 5.7 7.1 0.4 4.0 1 1 2 3 3 3 0 Swi5 FAM76 PF16046.5 EMC91287.1 - 8.3 5.7 21.9 1.4e+02 1.6 20.7 1.9 1 1 0 1 1 1 0 FAM76 protein V_ATPase_I PF01496.19 EMC91287.1 - 8.5 4.1 21.7 0.67 7.8 6.6 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family AcylCoA_dehyd_C PF12186.8 EMC91287.1 - 8.7 6.5 14.2 0.28 11.3 1.2 3.1 1 1 3 4 4 4 0 Acyl-CoA dehydrogenase C terminal CRT10 PF08728.10 EMC91287.1 - 9.2 4.3 12.6 10 4.1 12.6 1.0 1 0 0 1 1 1 0 CRT10 Nop25 PF09805.9 EMC91288.1 - 2e-37 128.7 11.2 2e-37 128.7 11.2 2.5 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.12 EMC91289.1 - 0.00068 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DAHP_synth_1 PF00793.20 EMC91290.1 - 8.1e-101 336.5 0.1 1e-100 336.1 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF1013 PF06242.11 EMC91290.1 - 0.12 12.5 0.2 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) RGM_N PF06535.12 EMC91291.1 - 0.062 13.5 0.2 0.11 12.7 0.2 1.5 1 1 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus DUF2834 PF11196.8 EMC91294.1 - 1.1e-05 25.6 14.9 0.0013 19.0 1.6 3.7 3 1 0 4 4 4 2 Protein of unknown function (DUF2834) FMO-like PF00743.19 EMC91295.1 - 1.6e-15 56.6 0.1 2.5e-13 49.3 0.2 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMC91295.1 - 2.1e-10 40.7 0.0 4.6e-09 36.4 0.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC91295.1 - 1.1e-07 31.4 0.0 0.0038 16.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC91295.1 - 1.7e-05 24.6 0.0 0.00057 19.6 0.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EMC91295.1 - 1.9e-05 24.0 0.1 0.00049 19.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMC91295.1 - 0.0071 15.6 0.1 0.7 9.1 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC91295.1 - 0.014 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EMC91295.1 - 0.045 13.7 0.0 0.79 9.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding LBR_tudor PF09465.10 EMC91295.1 - 0.11 12.4 1.1 0.41 10.5 0.1 2.5 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain Shikimate_DH PF01488.20 EMC91295.1 - 0.11 12.6 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GerD PF17898.1 EMC91295.1 - 0.13 12.2 0.0 3.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Spore germination GerD central core domain Diphthami_syn_2 PF01902.17 EMC91296.1 - 6e-19 68.4 0.0 1.8e-17 63.6 0.0 2.2 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EMC91296.1 - 2.3e-13 50.2 0.0 1.1e-06 28.7 0.0 3.2 3 0 0 3 3 3 2 Endoribonuclease L-PSP SelB-wing_1 PF09105.10 EMC91296.1 - 0.066 13.2 0.0 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Glyco_hydro_79C PF16862.5 EMC91297.1 - 1.6e-23 83.5 0.1 3.8e-23 82.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Frag1 PF10277.9 EMC91298.1 - 8.9e-47 159.4 14.8 1e-46 159.2 14.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLAC1 PF03595.17 EMC91298.1 - 3.5e-05 23.2 10.6 4.6e-05 22.8 10.6 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1345 PF07077.11 EMC91298.1 - 0.49 10.1 7.0 2.1 8.0 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF973 PF06157.11 EMC91298.1 - 0.62 9.1 9.5 1.5 7.8 9.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Ribosomal_L36e PF01158.18 EMC91299.1 - 1.9e-43 146.6 5.3 2.2e-43 146.4 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 EMC91299.1 - 0.027 14.5 0.1 0.03 14.4 0.1 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide HTH_38 PF13936.6 EMC91299.1 - 0.041 13.6 0.1 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain LemA PF04011.12 EMC91299.1 - 0.068 13.0 0.2 0.082 12.8 0.2 1.1 1 0 0 1 1 1 0 LemA family MRP-L28 PF09812.9 EMC91299.1 - 0.14 12.3 1.9 0.18 12.0 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 PITH PF06201.13 EMC91300.1 - 1.9e-38 132.0 0.0 2.9e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EMC91300.1 - 1.5e-28 98.7 0.0 3.1e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMC91300.1 - 2.2e-06 28.1 0.4 2.5e-05 24.7 0.4 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMC91300.1 - 3.6e-06 27.2 0.0 0.004 17.5 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EMC91300.1 - 2.9e-05 23.6 0.0 5.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EMC91300.1 - 0.0026 17.5 0.3 4.8 6.9 0.0 2.9 2 1 1 3 3 3 2 Redoxin Thioredoxin_9 PF14595.6 EMC91300.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 EMC91300.1 - 0.017 15.0 0.1 0.051 13.5 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family TUG-UBL1 PF11470.8 EMC91301.1 - 3e-24 85.0 0.1 5.9e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 EMC91301.1 - 1.1e-07 31.8 0.0 2.3e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 Raf-like Ras-binding domain UBX PF00789.20 EMC91301.1 - 0.00064 19.9 0.0 0.0037 17.4 0.0 2.3 2 0 0 2 2 2 1 UBX domain UN_NPL4 PF11543.8 EMC91301.1 - 0.0087 16.5 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-C2H2 PF00096.26 EMC91302.1 - 1.4e-12 47.3 14.2 6.7e-07 29.4 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC91302.1 - 2.4e-08 34.1 11.5 0.00041 21.0 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMC91302.1 - 3e-06 27.4 5.1 0.012 15.9 1.1 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EMC91302.1 - 4.1e-06 27.0 14.2 2.9e-05 24.3 6.5 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 EMC91302.1 - 1.9e-05 24.9 4.7 0.0063 16.9 0.3 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EMC91302.1 - 0.0021 18.0 9.6 0.081 13.0 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 EMC91302.1 - 0.0036 17.2 4.3 0.11 12.4 0.7 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 EMC91302.1 - 0.0039 16.8 3.6 0.79 9.4 0.7 2.6 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-UBR PF02207.20 EMC91302.1 - 0.12 12.5 1.7 0.27 11.4 1.7 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) LIM PF00412.22 EMC91302.1 - 0.2 11.9 4.2 0.53 10.6 4.2 1.7 1 0 0 1 1 1 0 LIM domain zf-C2H2_11 PF16622.5 EMC91302.1 - 0.28 11.0 9.4 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_UBZ PF18439.1 EMC91302.1 - 1.3 8.6 3.4 2.4 7.8 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 EMC91302.1 - 1.4 9.1 3.9 5.5 7.2 0.5 2.7 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 EMC91302.1 - 2.1 8.9 7.2 10 6.7 0.8 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 EMC91302.1 - 3.1 8.5 6.4 31 5.3 2.7 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 EMC91302.1 - 4 7.5 7.3 1.8 8.6 2.9 2.5 1 1 1 2 2 2 0 BED zinc finger Hid1 PF12722.7 EMC91302.1 - 8.1 4.4 6.2 11 4.0 6.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NAD_binding_4 PF07993.12 EMC91304.1 - 1.9e-44 151.8 0.0 3.2e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EMC91304.1 - 7.5e-22 77.5 0.0 1.5e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EMC91304.1 - 3.6e-08 33.2 0.0 6.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMC91304.1 - 1.9e-06 28.1 0.0 8.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 EMC91304.1 - 0.023 14.6 0.2 0.055 13.4 0.2 1.6 1 0 0 1 1 1 0 KR domain G-patch_2 PF12656.7 EMC91305.1 - 9.3e-24 83.3 0.6 9.3e-24 83.3 0.6 2.3 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 EMC91305.1 - 0.0014 18.5 3.1 0.0044 16.9 3.1 1.8 1 0 0 1 1 1 1 G-patch domain Glyco_transf_8 PF01501.20 EMC91306.1 - 0.012 15.1 0.4 0.02 14.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 8 MutS_V PF00488.21 EMC91310.1 - 1.3e-72 243.8 0.1 2.6e-72 242.8 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMC91310.1 - 8.2e-34 117.5 2.9 8.2e-34 117.5 2.9 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EMC91310.1 - 3.4e-30 104.6 0.0 8.9e-30 103.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EMC91310.1 - 5.1e-10 39.8 0.1 1.2e-08 35.3 0.0 3.2 3 0 0 3 3 3 1 MutS domain II DUF4911 PF16256.5 EMC91310.1 - 0.00053 19.9 0.1 0.0016 18.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4911) MutS_IV PF05190.18 EMC91310.1 - 0.0009 19.6 0.2 0.0043 17.4 0.2 2.3 1 0 0 1 1 1 1 MutS family domain IV DUF5437 PF17505.2 EMC91311.1 - 0.053 13.6 0.3 0.073 13.1 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5437) Velvet PF11754.8 EMC91312.1 - 8.9e-83 278.1 0.0 8.9e-83 278.1 0.0 2.3 3 0 0 3 3 3 1 Velvet factor APG5 PF04106.12 EMC91313.1 - 2.6e-65 220.2 0.0 3.5e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 Lactonase PF10282.9 EMC91314.1 - 1.8e-19 70.2 0.0 2.3e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 EMC91314.1 - 0.071 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Arylesterase WD40 PF00400.32 EMC91316.1 - 1.1e-21 76.7 19.3 8e-07 29.7 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 EMC91316.1 - 1.6e-18 66.9 0.6 3.1e-18 66.0 0.6 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EMC91316.1 - 0.011 14.4 5.6 0.067 11.8 3.5 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 INSIG PF07281.12 EMC91317.1 - 4.7e-72 242.1 1.3 5.9e-72 241.8 1.3 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) AICARFT_IMPCHas PF01808.18 EMC91318.1 - 1.5e-90 303.6 0.0 2.2e-90 303.1 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EMC91318.1 - 1.6e-23 82.7 0.0 2.7e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Myb_DNA-bind_6 PF13921.6 EMC91319.1 - 1.3e-15 57.3 0.0 0.00054 20.2 0.0 5.6 5 1 1 6 6 6 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMC91319.1 - 1.1e-14 54.4 0.2 0.00016 21.8 0.0 5.1 5 0 0 5 5 5 2 Myb-like DNA-binding domain HTH_38 PF13936.6 EMC91319.1 - 8.6e-11 41.4 2.0 0.00088 19.0 0.0 5.7 6 0 0 6 6 6 2 Helix-turn-helix domain GcrA PF07750.11 EMC91319.1 - 4.5e-06 27.2 0.3 0.039 14.4 0.1 3.4 3 1 0 3 3 3 2 GcrA cell cycle regulator HTH_23 PF13384.6 EMC91319.1 - 0.0002 21.1 2.6 1.7 8.6 0.0 4.8 4 1 1 5 5 5 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EMC91319.1 - 0.00068 19.3 0.5 18 5.1 0.0 4.9 6 0 0 6 6 6 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 EMC91319.1 - 0.0038 17.0 0.2 0.98 9.3 0.1 3.5 4 0 0 4 4 4 1 AsnC-type helix-turn-helix domain GerE PF00196.19 EMC91319.1 - 0.03 13.9 0.2 0.63 9.6 0.1 3.1 4 1 1 5 5 5 0 Bacterial regulatory proteins, luxR family HTH_Tnp_Tc3_1 PF11427.8 EMC91319.1 - 0.036 13.9 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 Tc3 transposase Sigma70_r4 PF04545.16 EMC91319.1 - 0.11 12.1 0.2 17 5.1 0.0 3.7 3 1 0 3 3 3 0 Sigma-70, region 4 PMM PF03332.13 EMC91320.1 - 1e-101 339.4 0.1 1.2e-101 339.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EMC91320.1 - 2e-05 24.4 0.0 8.4e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EMC91320.1 - 0.0014 18.2 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.13 EMC91320.1 - 0.039 13.2 0.1 0.055 12.7 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Trehalose_PPase PF02358.16 EMC91320.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase eIF2_C PF09173.11 EMC91321.1 - 2.9e-34 117.2 0.6 6.2e-34 116.1 0.6 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EMC91321.1 - 9e-23 80.8 0.1 6.4e-22 78.0 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EMC91321.1 - 4.6e-12 46.1 0.2 1e-11 45.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EMC91321.1 - 0.0019 18.1 0.1 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EMC91321.1 - 0.0056 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EMC91321.1 - 0.16 12.0 0.0 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 EMC91321.1 - 0.16 12.0 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Cpn60_TCP1 PF00118.24 EMC91322.1 - 4.2e-142 474.2 8.5 4.8e-142 474.0 8.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EMC91322.1 - 0.094 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat ADH_zinc_N PF00107.26 EMC91324.1 - 1e-26 93.5 0.8 1.6e-26 92.8 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC91324.1 - 9e-15 55.9 0.0 1.8e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EMC91324.1 - 0.0001 22.1 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.12 EMC91324.1 - 0.0048 16.8 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.19 EMC91325.1 - 6.4e-51 173.0 0.0 7.6e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMC91325.1 - 1.4e-31 109.8 0.1 1.8e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC91325.1 - 2.1e-15 57.0 0.0 6e-15 55.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMC91325.1 - 9.8e-14 51.1 0.0 6.6e-07 28.8 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EMC91325.1 - 1.8e-10 40.4 0.0 2.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EMC91325.1 - 7e-08 31.9 0.0 1.1e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EMC91325.1 - 2e-07 31.1 0.2 6.7e-07 29.4 0.2 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EMC91325.1 - 1.3e-05 24.7 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC91325.1 - 0.00058 19.5 0.0 0.0015 18.1 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EMC91325.1 - 0.00063 19.7 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sugar_tr PF00083.24 EMC91326.1 - 9.1e-67 225.9 26.1 1.1e-66 225.5 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC91326.1 - 4.7e-19 68.5 34.9 1.3e-16 60.5 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_3 PF13302.7 EMC91327.1 - 5.9e-25 88.6 0.0 7.4e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMC91327.1 - 3e-05 23.7 0.4 0.45 10.2 0.3 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC91327.1 - 5.9e-05 22.9 0.0 0.34 10.9 0.0 2.2 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.25 EMC91327.1 - 0.00031 21.0 0.0 0.011 16.0 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC91327.1 - 0.00071 20.0 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC91327.1 - 0.046 13.7 0.0 4.4 7.3 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 EMC91328.1 - 2.9e-60 204.2 40.6 6.9e-40 137.4 19.3 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EMC91328.1 - 5.7e-45 153.2 0.3 3.6e-27 95.5 0.0 3.5 3 0 0 3 3 3 2 ABC transporter MMR_HSR1 PF01926.23 EMC91328.1 - 5.9e-06 26.4 1.2 0.091 12.9 0.2 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EMC91328.1 - 7.3e-06 25.4 1.8 0.00055 19.3 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin SMC_N PF02463.19 EMC91328.1 - 1.7e-05 24.3 0.1 0.8 9.1 0.1 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMC91328.1 - 2.2e-05 24.9 0.3 0.2 12.0 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EMC91328.1 - 0.0011 18.9 0.8 1.1 9.0 0.0 3.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMC91328.1 - 0.0024 17.6 5.0 0.15 11.9 0.5 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMC91328.1 - 0.0074 16.2 2.7 1.2 9.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 EMC91328.1 - 0.012 15.8 0.2 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 EMC91328.1 - 0.099 11.6 1.5 5.8 5.8 0.3 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EMC91328.1 - 0.15 12.4 2.2 18 5.6 0.5 3.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EMC91328.1 - 0.15 11.4 0.1 9.8 5.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EMC91328.1 - 0.31 10.6 2.3 2.1 7.8 0.2 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EMC91328.1 - 0.31 10.8 2.7 10 5.8 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EMC91328.1 - 0.72 9.5 4.7 8.4 6.1 0.2 2.6 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EMC91329.1 - 4.7e-14 53.0 0.0 1.1e-13 51.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMC91329.1 - 0.014 15.8 0.1 0.23 11.8 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EMC91329.1 - 0.021 15.1 0.0 0.076 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMC91329.1 - 0.051 14.0 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EMC91329.1 - 0.059 13.2 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain Glyco_hydro_16 PF00722.21 EMC91329.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 zf-H2C2_2 PF13465.6 EMC91330.1 - 3.1e-13 49.5 16.8 9.8e-08 32.1 2.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EMC91330.1 - 8e-10 38.6 24.9 0.0059 17.0 8.2 3.8 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC91330.1 - 1.4e-06 28.6 21.5 0.028 15.2 6.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMC91330.1 - 9.1e-06 25.5 19.0 0.0052 16.8 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 EMC91330.1 - 0.0044 17.3 6.2 0.0086 16.3 6.2 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 EMC91330.1 - 0.029 14.2 0.3 0.086 12.7 0.3 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 EMC91330.1 - 0.2 12.0 8.4 3.7 7.9 2.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 EMC91330.1 - 0.21 11.9 1.7 0.54 10.6 1.7 1.7 1 1 0 1 1 1 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 EMC91330.1 - 0.24 11.5 7.1 0.23 11.6 2.2 2.6 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 EMC91330.1 - 0.39 10.8 8.3 1.9 8.6 7.5 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-CHCC PF10276.9 EMC91330.1 - 0.47 10.5 7.3 1.1 9.3 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-C2HE PF16278.5 EMC91330.1 - 0.48 10.9 15.3 0.72 10.3 0.8 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 EMC91330.1 - 0.66 9.9 6.6 0.28 11.1 0.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GAGA PF09237.11 EMC91330.1 - 1 9.2 8.6 0.44 10.4 1.5 2.8 1 1 2 3 3 3 0 GAGA factor zf-BED PF02892.15 EMC91330.1 - 8.9 6.4 11.5 11 6.1 6.6 2.9 1 1 1 2 2 2 0 BED zinc finger Glyco_hydro_76 PF03663.14 EMC91332.1 - 7e-45 154.1 28.7 1.1e-44 153.4 28.7 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMC91332.1 - 0.0021 17.2 6.5 0.011 14.9 0.0 2.8 1 1 1 3 3 3 1 Glycosyl Hydrolase Family 88 FMO-like PF00743.19 EMC91333.1 - 3e-14 52.4 0.0 3.2e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMC91333.1 - 4.7e-11 42.8 0.0 1.2e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMC91333.1 - 5.8e-11 42.2 0.0 1.5e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC91333.1 - 6.6e-10 38.7 0.0 1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC91333.1 - 8.9e-09 34.9 0.0 4.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 EMC91333.1 - 1.2e-08 35.0 0.1 0.00013 21.7 0.0 4.0 4 1 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMC91333.1 - 3.8e-06 27.4 0.1 0.057 14.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC91333.1 - 6e-06 25.6 0.0 0.018 14.2 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EMC91333.1 - 0.00019 20.6 0.0 0.0086 15.2 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein Mqo PF06039.15 EMC91333.1 - 0.00039 19.1 0.1 0.088 11.3 0.0 2.6 3 0 0 3 3 3 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 EMC91333.1 - 0.0019 18.2 0.0 0.31 11.0 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EMC91333.1 - 0.0034 17.5 0.0 0.053 13.6 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EMC91333.1 - 0.01 14.9 0.0 0.12 11.4 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 EMC91333.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding ApbA PF02558.16 EMC91333.1 - 0.1 12.3 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_transf_20 PF00982.21 EMC91334.1 - 8.6e-156 519.3 0.1 1.5e-155 518.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EMC91334.1 - 2.3e-39 134.9 0.1 9.3e-39 132.9 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase GPW_gp25 PF04965.14 EMC91334.1 - 0.0014 18.4 0.0 0.078 12.8 0.1 2.8 2 0 0 2 2 2 1 Gene 25-like lysozyme Sulfotransfer_4 PF17784.1 EMC91334.1 - 0.031 14.1 1.0 4 7.2 0.0 3.0 3 0 0 3 3 3 0 Sulfotransferase domain Cyclin PF08613.11 EMC91335.1 - 3.3e-40 138.1 9.7 6.1e-25 88.5 0.4 3.0 3 1 0 3 3 3 2 Cyclin DUF2524 PF10732.9 EMC91335.1 - 0.1 12.9 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Proteasome PF00227.26 EMC91336.1 - 9.7e-47 158.9 0.2 1.1e-46 158.7 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit SNF2_N PF00176.23 EMC91337.1 - 3.6e-65 220.0 0.0 9.9e-65 218.5 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 EMC91337.1 - 1.7e-10 40.6 9.0 3.4e-10 39.6 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC91337.1 - 4e-10 39.4 9.9 9.3e-10 38.2 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC91337.1 - 2.8e-08 33.5 10.4 5.9e-08 32.4 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC91337.1 - 1.3e-07 31.9 11.4 2.7e-07 30.8 11.4 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EMC91337.1 - 1.8e-07 30.9 7.0 3.7e-07 29.9 7.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EMC91337.1 - 4.3e-06 26.6 8.5 1e-05 25.4 8.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMC91337.1 - 3.4e-05 23.7 10.9 6.5e-05 22.8 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EMC91337.1 - 0.00013 22.2 9.7 0.00034 20.8 9.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 EMC91337.1 - 0.00016 22.0 0.0 0.00092 19.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 EMC91337.1 - 0.00061 19.9 9.8 0.0016 18.6 9.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 EMC91337.1 - 0.014 15.3 1.2 0.028 14.4 0.6 1.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Pico_P2A PF00947.19 EMC91337.1 - 0.11 12.5 0.4 0.23 11.5 0.4 1.5 1 0 0 1 1 1 0 Picornavirus core protein 2A KxDL PF10241.9 EMC91337.1 - 0.41 10.9 3.9 22 5.4 0.2 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein zf-Di19 PF05605.12 EMC91337.1 - 3.8 7.9 8.7 15 6.0 0.1 3.8 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-P11 PF03854.14 EMC91337.1 - 5.8 6.7 7.9 11 5.7 7.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 EMC91337.1 - 5.9 6.6 10.3 12 5.6 10.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type MFS_1 PF07690.16 EMC91338.1 - 4.6e-21 75.1 23.1 1e-18 67.4 16.7 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Trm112p PF03966.16 EMC91339.1 - 3.5e-14 53.1 0.1 5.7e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 EMC91339.1 - 0.012 16.1 0.2 0.023 15.2 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF2554 PF10829.8 EMC91339.1 - 0.35 11.3 1.2 0.47 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) Rad60-SLD PF11976.8 EMC91342.1 - 8.3e-15 54.4 0.1 5.9e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TmoB PF06234.12 EMC91342.1 - 0.0018 18.4 0.9 0.0097 16.0 0.1 2.3 2 0 0 2 2 2 1 Toluene-4-monooxygenase system protein B (TmoB) TUG-UBL1 PF11470.8 EMC91342.1 - 0.0019 18.3 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain ubiquitin PF00240.23 EMC91342.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Ufm1 PF03671.14 EMC91342.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein MAP17 PF15807.5 EMC91342.1 - 1.7 8.9 6.5 2.6 8.3 4.0 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Methyltransf_11 PF08241.12 EMC91343.1 - 4.9e-18 65.6 0.0 8.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC91343.1 - 6.7e-16 58.8 0.0 1.4e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC91343.1 - 3.7e-09 36.3 0.0 6.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMC91343.1 - 1.9e-08 35.0 0.0 4.8e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC91343.1 - 1.9e-08 34.3 0.0 4.9e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC91343.1 - 9.9e-07 28.7 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EMC91343.1 - 0.00023 21.1 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 EMC91343.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.12 EMC91343.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase zf-C3HC4_3 PF13920.6 EMC91345.1 - 1.1e-05 25.2 9.5 1.1e-05 25.2 9.5 3.6 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) THOC7 PF05615.13 EMC91346.1 - 0.67 10.2 7.2 1.3 9.3 7.2 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 ApoLp-III PF07464.11 EMC91346.1 - 4.7 7.3 9.8 18 5.4 9.7 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Herpes_gI PF01688.17 EMC91348.1 - 0.028 14.3 2.8 0.13 12.2 0.1 2.5 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein I Arrestin_N PF00339.29 EMC91349.1 - 7.5e-16 58.5 0.0 4.9e-15 55.9 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EMC91349.1 - 2.9e-05 24.5 0.0 0.016 15.7 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Response_reg PF00072.24 EMC91350.1 - 2.9e-20 72.5 0.3 8.3e-20 71.0 0.3 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EMC91350.1 - 1.2e-18 67.6 0.0 2.4e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMC91350.1 - 6.7e-05 22.8 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain FmiP_Thoc5 PF09766.9 EMC91351.1 - 2.4e-27 96.2 12.9 3e-27 95.9 12.9 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF4140 PF13600.6 EMC91351.1 - 0.45 11.0 12.2 2.6 8.5 2.6 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) BRE1 PF08647.11 EMC91351.1 - 2.1 8.5 15.5 1.7 8.8 5.8 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase NMO PF03060.15 EMC91352.1 - 1.9e-26 93.3 4.4 2.8e-19 69.7 2.3 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EMC91352.1 - 1.8e-06 27.3 1.9 3.7e-06 26.2 1.7 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMC91352.1 - 1.3e-05 24.4 0.4 9.1e-05 21.6 0.4 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMC91352.1 - 0.046 12.9 3.0 0.024 13.8 0.6 1.6 2 0 0 2 2 2 0 Conserved region in glutamate synthase RabGAP-TBC PF00566.18 EMC91353.1 - 3.1e-34 118.5 0.0 5.3e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EMC91353.1 - 5.2e-06 25.0 1.4 5.2e-06 25.0 1.4 1.9 2 0 0 2 2 2 1 SBE2, cell-wall formation HlyIII PF03006.20 EMC91355.1 - 2.1e-61 207.5 18.4 2.6e-61 207.2 18.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related p450 PF00067.22 EMC91356.1 - 2e-52 178.5 0.0 2.6e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RSN1_7TM PF02714.15 EMC91357.1 - 5e-73 245.8 21.9 5e-73 245.8 21.9 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMC91357.1 - 3.6e-37 127.5 1.0 3.6e-37 127.5 1.0 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMC91357.1 - 2.8e-35 122.1 0.0 5.3e-35 121.2 0.0 1.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter AAA PF00004.29 EMC91359.1 - 3.4e-29 101.9 0.0 6.6e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMC91359.1 - 1e-06 29.2 0.0 2.7e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMC91359.1 - 4.7e-06 26.9 0.2 2.5e-05 24.6 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 EMC91359.1 - 7e-06 26.6 0.0 3.3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMC91359.1 - 3.7e-05 23.9 0.1 7.5e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMC91359.1 - 0.00034 20.2 0.1 0.11 12.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EMC91359.1 - 0.00039 20.2 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA_14 PF13173.6 EMC91359.1 - 0.00054 20.0 0.0 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMC91359.1 - 0.00061 20.1 0.3 0.0011 19.3 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Sigma54_activat PF00158.26 EMC91359.1 - 0.0009 19.0 0.1 0.0021 17.8 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_17 PF13207.6 EMC91359.1 - 0.0016 18.9 0.0 0.0046 17.4 0.0 1.8 1 1 1 2 2 1 1 AAA domain NACHT PF05729.12 EMC91359.1 - 0.0019 18.2 0.0 0.004 17.1 0.0 1.8 1 1 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.21 EMC91359.1 - 0.0032 16.9 0.0 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EMC91359.1 - 0.0041 17.1 0.0 2.3 8.1 0.0 2.3 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EMC91359.1 - 0.0052 17.3 0.0 0.009 16.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EMC91359.1 - 0.0056 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 EMC91359.1 - 0.0072 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EMC91359.1 - 0.0087 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 EMC91359.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EMC91359.1 - 0.013 15.8 0.0 0.055 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EMC91359.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EMC91359.1 - 0.02 14.7 0.0 0.057 13.2 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EMC91359.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EMC91359.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMC91359.1 - 0.032 14.3 0.0 0.09 12.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_2 PF07724.14 EMC91359.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATP_bind_1 PF03029.17 EMC91359.1 - 0.054 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 EMC91359.1 - 0.06 12.5 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF815) KTI12 PF08433.10 EMC91359.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.6 EMC91359.1 - 0.067 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EMC91359.1 - 0.078 11.6 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMC91359.1 - 0.08 12.7 0.0 0.22 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMC91359.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ADK PF00406.22 EMC91359.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase CLP1_P PF16575.5 EMC91359.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Ploopntkinase3 PF18751.1 EMC91359.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 EMC91359.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 EMC91359.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 EMC91359.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SKI PF01202.22 EMC91359.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.22 EMC91359.1 - 0.18 10.9 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Myb_DNA-bind_6 PF13921.6 EMC91360.1 - 9.7e-11 41.8 8.5 1e-10 41.7 4.7 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 EMC91360.1 - 1.4e-08 34.9 2.0 1.4e-08 34.9 2.0 5.0 6 0 0 6 6 6 1 HSA Myb_DNA-binding PF00249.31 EMC91360.1 - 0.0093 16.1 1.7 0.022 14.9 1.7 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.32 EMC91361.1 - 3.8e-10 40.2 0.1 0.27 12.2 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC91361.1 - 0.00025 21.3 0.0 18 5.7 0.0 5.1 5 2 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain N-SET PF11764.8 EMC91362.1 - 1.3e-53 181.7 0.8 1.3e-53 181.7 0.8 3.1 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EMC91362.1 - 5.8e-26 89.9 0.0 1.4e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 EMC91362.1 - 2.2e-20 73.7 6.5 2.1e-19 70.5 0.1 3.6 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.22 EMC91362.1 - 0.00058 19.6 0.3 0.0076 16.0 0.1 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4962 PF16332.5 EMC91362.1 - 0.23 9.9 0.9 0.41 9.1 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) DMRL_synthase PF00885.19 EMC91363.1 - 7.7e-53 178.1 0.0 1.5e-52 177.2 0.0 1.4 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase eIF2A PF08662.11 EMC91364.1 - 6.5e-38 130.6 5.1 2.1e-35 122.4 0.4 4.3 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EMC91364.1 - 4.8e-07 29.5 0.0 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EMC91364.1 - 0.0029 18.4 1.6 1.2 10.1 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EMC91364.1 - 0.0033 16.6 0.0 0.62 9.0 0.0 2.9 2 1 1 3 3 3 3 Coatomer WD associated region RRM_2 PF04059.12 EMC91364.1 - 0.021 15.0 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif 2 DUF3883 PF13020.6 EMC91365.1 - 8.6e-06 25.7 0.0 2.7e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 EMC91365.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AlaDh_PNT_N PF05222.15 EMC91366.1 - 1.2e-28 100.1 0.0 2.4e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EMC91366.1 - 0.0002 20.8 0.0 0.0005 19.4 0.0 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 EMC91367.1 - 1.2e-67 228.0 0.0 1.7e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC91367.1 - 6.6e-43 146.9 0.0 9.2e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC91367.1 - 7.8e-11 41.8 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EMC91367.1 - 4.4e-06 25.9 0.2 9.3e-06 24.8 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMC91367.1 - 0.0088 15.4 0.1 0.029 13.7 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMC91367.1 - 0.01 15.8 2.5 1.3 8.9 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 EMC91367.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Cucumo_2B PF03263.13 EMC91367.1 - 0.2 12.1 0.8 0.49 10.9 0.8 1.6 1 0 0 1 1 1 0 Cucumovirus protein 2B PRP3 PF08572.10 EMC91367.1 - 1.1 9.0 4.9 2.4 7.8 4.9 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) AP_endonuc_2 PF01261.24 EMC91368.1 - 2.2e-39 135.1 0.0 3.3e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MADF_DNA_bdg PF10545.9 EMC91368.1 - 0.26 11.6 1.7 0.75 10.2 0.4 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Methyltransf_25 PF13649.6 EMC91369.1 - 9.8e-08 32.6 0.1 4.2e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC91369.1 - 2e-07 31.7 0.0 3.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC91369.1 - 3.1e-07 30.9 0.1 8.4e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC91369.1 - 0.00064 19.6 0.0 0.0018 18.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC91369.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC91369.1 - 0.0041 16.7 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain AAA_16 PF13191.6 EMC91371.1 - 3.2e-12 47.1 2.0 3.3e-10 40.6 1.9 3.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EMC91371.1 - 4.6e-12 46.4 0.1 1.4e-10 41.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EMC91371.1 - 5.2e-11 43.1 0.0 5e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 EMC91371.1 - 2e-06 27.7 0.1 2.3e-05 24.3 0.1 2.4 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_5 PF07728.14 EMC91371.1 - 5.3e-06 26.5 0.0 0.00022 21.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EMC91371.1 - 3e-05 24.4 0.9 0.0061 16.9 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_7 PF12775.7 EMC91371.1 - 0.0001 21.9 0.0 0.0045 16.5 0.0 2.3 1 1 1 2 2 2 1 P-loop containing dynein motor region AAA_lid_10 PF17872.1 EMC91371.1 - 0.00012 22.2 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_30 PF13604.6 EMC91371.1 - 0.00018 21.3 0.0 0.0017 18.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EMC91371.1 - 0.00037 20.4 0.1 0.0013 18.6 0.1 1.9 1 1 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.21 EMC91371.1 - 0.0044 16.4 0.0 0.4 10.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EMC91371.1 - 0.0069 16.2 0.4 0.27 11.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 EMC91371.1 - 0.0096 15.6 0.0 0.033 13.9 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA12 PF10443.9 EMC91371.1 - 0.0097 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein DUF815 PF05673.13 EMC91371.1 - 0.01 15.0 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EMC91371.1 - 0.011 15.6 0.0 0.034 14.1 0.0 1.9 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 EMC91371.1 - 0.023 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EMC91371.1 - 0.027 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 EMC91371.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase ATPase_2 PF01637.18 EMC91371.1 - 0.039 13.9 0.0 0.31 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EMC91371.1 - 0.06 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EMC91371.1 - 0.065 13.4 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 EMC91371.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase KTI12 PF08433.10 EMC91371.1 - 0.082 12.3 0.0 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 EMC91371.1 - 0.092 13.3 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EMC91371.1 - 0.15 11.7 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_32 PF13654.6 EMC91371.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EMC91371.1 - 0.2 10.8 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2700 PF10912.8 EMC91372.1 - 0.0018 18.3 0.1 0.63 10.1 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2700) Yip1 PF04893.17 EMC91372.1 - 0.018 14.7 0.5 0.033 13.9 0.5 1.4 1 0 0 1 1 1 0 Yip1 domain DUF4271 PF14093.6 EMC91372.1 - 0.026 14.5 0.3 0.026 14.5 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF3464 PF11947.8 EMC91372.1 - 0.028 14.1 4.0 0.45 10.3 1.2 2.5 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 DUF1772 PF08592.11 EMC91372.1 - 0.068 13.5 3.6 0.091 13.1 2.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF1218 PF06749.12 EMC91372.1 - 0.14 12.7 1.6 0.35 11.4 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) DUF3611 PF12263.8 EMC91372.1 - 0.5 10.2 6.1 0.75 9.7 0.8 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3611) MARVEL PF01284.23 EMC91372.1 - 2.3 8.2 8.6 6.7 6.7 7.8 2.3 1 1 0 1 1 1 0 Membrane-associating domain zf-TFIIB PF13453.6 EMC91374.1 - 0.83 9.0 5.0 0.21 10.9 0.5 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C2H2_3 PF13878.6 EMC91374.1 - 3.4 7.6 4.4 3.8 7.4 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Cys_knot PF00007.22 EMC91374.1 - 7.7 6.9 15.6 5.5 7.3 2.1 3.4 2 1 1 3 3 3 0 Cystine-knot domain IBR PF01485.21 EMC91374.1 - 8.5 6.7 8.6 29 5.0 0.1 3.2 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain CENP-L PF13092.6 EMC91375.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 Enolase_C PF00113.22 EMC91377.1 - 3.9e-154 512.2 0.1 5.4e-154 511.7 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EMC91377.1 - 6.5e-58 194.6 0.4 1.1e-57 193.9 0.4 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EMC91377.1 - 1.7e-06 27.8 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EMC91377.1 - 0.0067 15.6 1.5 0.024 13.8 0.2 2.2 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus AAA PF00004.29 EMC91378.1 - 9.7e-43 145.8 0.0 1.7e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EMC91378.1 - 7.4e-11 41.8 0.1 3.7e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EMC91378.1 - 3.5e-10 39.5 0.2 8e-10 38.4 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EMC91378.1 - 7.2e-08 33.0 0.0 6.2e-05 23.5 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EMC91378.1 - 1.9e-06 27.9 0.1 3.5e-05 23.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMC91378.1 - 2.7e-06 27.6 0.0 8.7e-06 26.0 0.0 1.9 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EMC91378.1 - 8.2e-06 25.6 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMC91378.1 - 0.00016 21.9 0.1 0.0063 16.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EMC91378.1 - 0.00042 19.6 0.0 0.00087 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EMC91378.1 - 0.00079 20.0 0.0 0.0029 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EMC91378.1 - 0.0015 18.1 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EMC91378.1 - 0.0022 17.3 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EMC91378.1 - 0.0031 17.7 0.0 0.0095 16.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 EMC91378.1 - 0.0037 16.7 0.0 0.0078 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EMC91378.1 - 0.0044 17.0 0.0 0.0091 16.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EMC91378.1 - 0.0058 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EMC91378.1 - 0.0073 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EMC91378.1 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EMC91378.1 - 0.012 15.4 0.0 0.038 13.7 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 EMC91378.1 - 0.013 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMC91378.1 - 0.018 14.8 0.0 0.06 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 EMC91378.1 - 0.03 13.7 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 KaiC Prot_ATP_OB_N PF17758.1 EMC91378.1 - 0.038 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_30 PF13604.6 EMC91378.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMC91378.1 - 0.057 13.3 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EMC91378.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EMC91378.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMC91378.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMC91378.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 EMC91378.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EMC91378.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 COesterase PF00135.28 EMC91380.1 - 1.1e-65 222.5 0.2 2.5e-65 221.3 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC91380.1 - 1.9e-07 31.1 0.1 4.1e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold MOSC PF03473.17 EMC91381.1 - 1.7e-30 105.7 0.0 3.9e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 EMC91381.1 - 2e-26 92.8 0.0 3.9e-26 91.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 EMC91381.1 - 3.4e-23 81.8 0.0 6.7e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SHR3_chaperone PF08229.11 EMC91382.1 - 1.2e-79 265.7 0.0 1.7e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 EMC91382.1 - 0.055 13.4 1.1 0.22 11.5 0.1 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5453) MCU PF04678.13 EMC91382.1 - 0.22 11.6 0.6 0.6 10.2 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial calcium uniporter LSM PF01423.22 EMC91383.1 - 1.6e-21 75.8 0.0 1.8e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.20 EMC91384.1 - 9.5e-15 54.7 0.0 1.1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease PPTA PF01239.22 EMC91385.1 - 5.3e-40 134.0 28.3 7.6e-10 38.2 0.4 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat PALP PF00291.25 EMC91386.1 - 1.3e-58 198.7 2.0 1.6e-58 198.5 2.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Polyoma_coat2 PF00761.20 EMC91386.1 - 0.11 12.1 0.3 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein Proteasome PF00227.26 EMC91387.1 - 2e-40 138.3 0.0 2.4e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit OPT PF03169.15 EMC91390.1 - 5.1e-89 299.6 44.0 7.8e-89 299.0 44.0 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Mpv17_PMP22 PF04117.12 EMC91390.1 - 1.1 9.6 6.5 0.16 12.2 1.3 2.5 2 0 0 2 2 2 0 Mpv17 / PMP22 family Prenyltrans PF00432.21 EMC91392.1 - 6.1e-29 99.5 16.7 4e-07 29.6 0.1 6.1 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EMC91392.1 - 0.001 18.3 0.0 0.082 12.0 0.0 2.1 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EMC91392.1 - 0.0023 17.1 0.0 1.2 8.2 0.0 2.9 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 EMC91392.1 - 0.08 11.9 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 A-macroglobulin TED domain AA_permease PF00324.21 EMC91393.1 - 5.2e-150 500.2 33.3 6.1e-150 500.0 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMC91393.1 - 5.7e-42 144.0 35.1 7.3e-42 143.7 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 EMC91394.1 - 1.5e-06 28.0 0.1 1.5e-06 28.0 0.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EMC91394.1 - 0.0037 17.1 0.3 0.0074 16.2 0.3 1.5 1 0 0 1 1 1 1 F-box domain tRNA-synt_1g PF09334.11 EMC91395.1 - 1.9e-80 270.5 0.0 2.3e-78 263.7 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EMC91395.1 - 4.1e-16 58.4 1.3 1.4e-09 36.8 0.0 3.8 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EMC91395.1 - 6.9e-05 22.3 0.0 0.035 13.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EMC91395.1 - 0.045 13.7 0.0 1.5 8.8 0.0 2.4 1 1 1 2 2 2 0 Anticodon-binding domain of tRNA WW PF00397.26 EMC91396.1 - 3.4e-11 43.0 0.2 8.9e-11 41.7 0.2 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 EMC91396.1 - 0.016 14.3 0.0 0.062 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoD-like phosphatase Peptidase_M48_N PF16491.5 EMC91397.1 - 2.6e-60 203.4 5.1 2.6e-60 203.4 5.1 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EMC91397.1 - 4.6e-42 144.0 0.0 6.8e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EMC91397.1 - 0.0036 16.5 0.2 0.01 15.0 0.2 1.5 1 1 0 1 1 1 1 BlaR1 peptidase M56 zf-C2H2_3 PF13878.6 EMC91398.1 - 0.38 10.6 8.8 16 5.5 0.7 3.8 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO Attractin PF08037.11 EMC91398.1 - 3.1 7.9 8.1 4.9 7.2 0.3 2.8 1 1 1 2 2 2 0 Attractin family Ribosomal_L34 PF00468.17 EMC91400.1 - 2.8e-18 65.6 12.7 4.8e-18 64.8 12.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 zf-U11-48K PF05253.12 EMC91400.1 - 0.17 11.9 0.3 0.25 11.3 0.3 1.3 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger Syja_N PF02383.18 EMC91401.1 - 2.1e-75 254.0 0.0 2.9e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EMC91401.1 - 4e-08 33.1 0.0 7.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sec10 PF07393.11 EMC91403.1 - 1.2e-144 483.5 0.0 2.2e-144 482.6 0.0 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 EMC91403.1 - 4.7e-07 29.5 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMC91403.1 - 9e-07 28.7 0.1 2.5e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like Hydrolase_4 PF12146.8 EMC91404.1 - 3.6e-16 59.2 0.0 2.3e-10 40.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMC91404.1 - 9.6e-09 35.2 0.0 7.1e-07 29.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC91404.1 - 3e-06 28.0 0.0 1.2e-05 26.1 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 EMC91404.1 - 1.7e-05 23.7 0.0 0.14 10.8 0.1 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 EMC91404.1 - 0.00064 19.7 0.0 0.023 14.6 0.0 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EMC91404.1 - 0.001 18.6 0.0 0.0042 16.6 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EMC91404.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 EMC91404.1 - 0.0017 17.4 0.1 0.0024 16.9 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 EMC91404.1 - 0.0019 17.8 0.1 0.13 11.8 0.0 2.9 3 1 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EMC91404.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EMC91404.1 - 0.012 15.4 0.0 0.29 10.9 0.0 2.3 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EMC91404.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EMC91404.1 - 0.081 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein MCM PF00493.23 EMC91405.1 - 5.8e-103 342.8 0.0 8.6e-103 342.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMC91405.1 - 5.3e-32 110.3 0.4 9.8e-32 109.5 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 EMC91405.1 - 4.4e-20 72.2 0.1 9.6e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 EMC91405.1 - 1.9e-18 66.6 0.2 5.7e-18 65.1 0.2 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EMC91405.1 - 1.3e-06 28.0 0.0 9.5e-05 21.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMC91405.1 - 3.8e-06 26.9 0.0 1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EMC91405.1 - 0.0016 18.3 0.0 0.0046 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 EMC91405.1 - 0.047 14.3 0.3 0.2 12.3 0.2 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 EMC91405.1 - 0.071 13.0 0.1 0.25 11.2 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMC91405.1 - 0.077 12.7 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF5133 PF17196.4 EMC91405.1 - 0.17 12.1 0.5 2 8.7 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) zf-HYPF PF07503.12 EMC91405.1 - 1.2 9.0 3.2 1.4 8.7 0.2 2.5 2 0 0 2 2 2 0 HypF finger bZIP_1 PF00170.21 EMC91406.1 - 0.048 13.7 3.7 0.1 12.7 3.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor Oxidored_molyb PF00174.19 EMC91406.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain Methyltransf_12 PF08242.12 EMC91408.1 - 3.7e-15 56.5 0.0 1.1e-14 55.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC91408.1 - 7.2e-12 45.9 0.0 2.3e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC91408.1 - 3.4e-10 40.0 0.0 5.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC91408.1 - 2.5e-06 28.0 0.0 8.8e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 EMC91408.1 - 8.2e-05 23.6 0.0 0.00017 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EMC91408.1 - 0.00013 21.2 0.0 0.025 13.8 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 EMC91408.1 - 0.002 18.0 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC91408.1 - 0.0068 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Polyketide_cyc PF03364.20 EMC91409.1 - 2e-18 66.8 0.0 3.1e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EMC91409.1 - 0.00027 21.2 0.1 0.52 10.6 0.0 2.3 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Bax1-I PF01027.20 EMC91410.1 - 1.3e-53 181.9 29.0 1.5e-53 181.7 29.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SfLAP PF11139.8 EMC91410.1 - 0.015 14.7 0.8 0.015 14.7 0.8 2.8 3 1 0 3 3 3 0 Sap, sulfolipid-1-addressing protein DUF3754 PF12576.8 EMC91410.1 - 0.16 11.9 0.7 0.41 10.6 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Transport_MerF PF11431.8 EMC91410.1 - 0.17 11.8 2.2 1.5 8.8 0.1 3.3 3 0 0 3 3 3 0 Membrane transport protein MerF DUF5504 PF17608.2 EMC91410.1 - 2.2 8.4 15.5 1.4 9.0 4.9 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5504) Ecm29 PF13001.7 EMC91411.1 - 1.8e-153 511.8 0.0 3.7e-152 507.5 0.0 2.6 2 0 0 2 2 2 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 EMC91411.1 - 1.8e-05 25.2 0.0 0.0037 17.8 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EMC91411.1 - 8.5e-05 22.5 9.1 0.44 11.0 0.0 8.2 10 0 0 10 10 10 1 HEAT repeat R3H PF01424.22 EMC91411.1 - 0.078 13.0 1.0 0.33 11.0 0.3 2.5 2 0 0 2 2 2 0 R3H domain V4R PF02830.18 EMC91411.1 - 0.16 12.0 0.0 0.54 10.3 0.0 2.0 1 0 0 1 1 1 0 V4R domain Fungal_trans_2 PF11951.8 EMC91412.1 - 1.1e-11 44.2 0.9 1.7e-11 43.6 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC91412.1 - 2.2e-06 27.7 10.3 4.4e-06 26.7 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain M20_dimer PF07687.14 EMC91413.1 - 6.9e-20 71.0 0.0 1.5e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EMC91413.1 - 9.7e-16 58.1 0.2 2.3e-11 43.8 0.1 2.4 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 R3H PF01424.22 EMC91414.1 - 1.7e-16 60.0 0.1 3.3e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EMC91414.1 - 3.8e-06 26.8 52.4 4.8e-05 23.3 12.3 14.7 16 4 1 17 17 17 7 NF-X1 type zinc finger Pro_isomerase PF00160.21 EMC91415.1 - 2.9e-50 170.6 0.1 7.5e-50 169.3 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EMC91415.1 - 6.4e-07 30.0 0.0 0.12 13.3 0.1 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EMC91415.1 - 8.8e-05 21.6 0.7 0.056 12.4 0.1 3.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EMC91415.1 - 0.00052 20.3 0.0 0.27 11.6 0.0 3.9 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain ADK PF00406.22 EMC91416.1 - 1e-45 155.5 0.0 1.4e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EMC91416.1 - 9.1e-39 133.0 0.3 1.4e-38 132.4 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMC91416.1 - 1.1e-09 38.9 0.0 1.5e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EMC91416.1 - 8.3e-07 28.9 0.4 0.033 13.9 0.2 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EMC91416.1 - 1.7e-05 25.0 0.2 0.00022 21.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 EMC91416.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Hydin_ADK PF17213.3 EMC91416.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Viral_helicase1 PF01443.18 EMC91416.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EMC91416.1 - 0.32 10.3 2.1 1.7 7.9 2.1 2.0 1 1 0 1 1 1 0 Zeta toxin RhoGEF PF00621.20 EMC91419.1 - 5e-37 127.9 0.0 4.5e-36 124.8 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 EMC91419.1 - 1.5e-14 54.2 0.1 1.5e-14 54.2 0.1 2.9 3 0 0 3 3 3 1 BAR domain CREPT PF16566.5 EMC91419.1 - 0.043 14.0 0.1 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Abhydrolase_3 PF07859.13 EMC91420.1 - 6.6e-15 55.5 0.0 7.2e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EMC91420.1 - 1.6e-05 24.1 0.0 1.6e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 EMC91420.1 - 3e-05 23.1 0.0 3e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 EMC91420.1 - 0.00011 21.2 0.1 0.00043 19.3 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EMC91420.1 - 0.0056 17.3 0.0 0.0062 17.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EMC91420.1 - 0.0059 16.1 0.1 0.043 13.3 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EMC91420.1 - 0.034 13.8 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EMC91420.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 EMC91420.1 - 0.14 11.8 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.12 EMC91420.1 - 0.15 10.7 0.0 0.25 10.0 0.0 1.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) AzlD PF05437.12 EMC91422.1 - 0.019 15.1 8.9 0.019 15.1 8.9 1.7 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF1129 PF06570.11 EMC91422.1 - 3.3 7.2 5.4 3.6 7.0 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF2070 PF09843.9 EMC91422.1 - 4.1 5.6 10.4 4.8 5.3 10.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ilm1 PF10311.9 EMC91423.1 - 6.3e-57 191.8 0.9 7.1e-57 191.6 0.9 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Peptidase_M19 PF01244.21 EMC91424.1 - 7.2e-96 321.1 0.0 8.5e-96 320.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) SUV3_C PF12513.8 EMC91424.1 - 0.08 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal UPF0242 PF06785.11 EMC91425.1 - 0.011 15.8 12.9 0.011 15.8 12.9 3.0 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YmgD PF16456.5 EMC91425.1 - 0.14 12.2 3.6 0.34 11.0 0.5 2.9 2 1 1 3 3 3 0 YmgD protein Tup_N PF08581.10 EMC91425.1 - 2.9 8.2 19.3 2.7 8.4 1.4 3.7 3 1 0 3 3 3 0 Tup N-terminal Exonuc_VII_L PF02601.15 EMC91425.1 - 5.4 6.5 24.2 1.2 8.6 9.2 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2563 PF10817.8 EMC91425.1 - 7.9 7.1 7.2 8.1 7.1 0.2 3.5 2 2 3 5 5 5 0 Protein of unknown function (DUF2563) MFS_1 PF07690.16 EMC91426.1 - 1.9e-48 165.2 35.9 1.9e-48 165.2 35.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC91426.1 - 8.8e-10 38.0 15.4 8.8e-10 38.0 15.4 3.2 2 2 0 2 2 2 1 Sugar (and other) transporter LapA_dom PF06305.11 EMC91426.1 - 0.0021 17.8 9.4 3.1 7.7 1.3 4.4 4 0 0 4 4 4 3 Lipopolysaccharide assembly protein A domain GWT1 PF06423.12 EMC91426.1 - 0.098 12.8 5.0 2.7 8.1 0.1 3.5 3 1 0 3 3 3 0 GWT1 GST_C_3 PF14497.6 EMC91429.1 - 1.6e-06 28.2 0.0 4.7e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMC91429.1 - 1.8e-06 28.2 0.0 7.9e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMC91429.1 - 5.5e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMC91429.1 - 8e-05 22.9 0.0 0.00019 21.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMC91429.1 - 8.5e-05 22.9 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMC91429.1 - 0.00059 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNA_pol_L_2 PF13656.6 EMC91430.1 - 8.4e-27 92.8 0.0 1.3e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EMC91430.1 - 1.9e-11 43.2 0.0 1.6e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Alpha-amylase PF00128.24 EMC91434.1 - 5.1e-36 124.9 0.0 8.6e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EMC91434.1 - 0.045 13.9 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Sugar_tr PF00083.24 EMC91435.1 - 8.9e-83 278.6 21.6 1.1e-82 278.4 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC91435.1 - 1.7e-17 63.4 39.8 8.7e-12 44.6 20.0 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Coatomer_E PF04733.14 EMC91435.1 - 0.022 14.2 0.2 0.051 13.0 0.0 1.6 2 0 0 2 2 2 0 Coatomer epsilon subunit MFS_1_like PF12832.7 EMC91435.1 - 0.76 8.6 15.3 0.0088 14.9 6.0 2.0 2 0 0 2 2 2 0 MFS_1 like family Zn_clus PF00172.18 EMC91436.1 - 4.9e-08 33.0 10.3 7.5e-08 32.4 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.21 EMC91437.1 - 6.1e-164 546.6 0.2 7e-164 546.4 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AflR PF08493.10 EMC91437.1 - 0.11 12.0 0.4 0.17 11.3 0.4 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein ABC_tran PF00005.27 EMC91438.1 - 2.1e-49 167.5 0.2 2.4e-28 99.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMC91438.1 - 2.6e-29 102.7 10.6 2.6e-29 102.7 10.6 2.5 3 0 0 3 3 3 1 ABC transporter transmembrane region AAA_21 PF13304.6 EMC91438.1 - 9.5e-06 25.6 4.5 0.64 9.8 0.0 3.5 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMC91438.1 - 1.2e-05 24.9 7.3 0.022 14.2 0.1 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMC91438.1 - 1.3e-05 25.6 2.2 0.011 16.1 0.4 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EMC91438.1 - 1.8e-05 25.0 0.6 0.059 13.6 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMC91438.1 - 3.7e-05 23.4 3.3 0.072 12.8 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMC91438.1 - 7.7e-05 22.6 0.4 0.13 12.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EMC91438.1 - 0.0003 20.5 0.2 0.22 11.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMC91438.1 - 0.00053 20.1 0.1 0.22 11.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EMC91438.1 - 0.0017 17.8 0.7 0.87 8.9 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family cobW PF02492.19 EMC91438.1 - 0.011 15.4 1.9 2.9 7.4 0.1 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EMC91438.1 - 0.014 14.5 0.2 2.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 EMC91438.1 - 0.017 15.7 0.2 5.3 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMC91438.1 - 0.039 13.5 0.1 5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 EMC91438.1 - 0.044 13.5 0.6 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EMC91438.1 - 0.046 13.9 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMC91438.1 - 0.053 13.4 2.6 3.7 7.5 0.1 3.0 3 0 0 3 3 3 0 NACHT domain ATP-synt_ab PF00006.25 EMC91438.1 - 0.088 12.5 0.1 1.7 8.3 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 EMC91438.1 - 0.12 11.9 3.5 2.3 7.8 0.2 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EMC91438.1 - 0.2 11.6 1.3 3.8 7.5 0.1 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.14 EMC91438.1 - 0.35 10.7 1.3 3.3 7.6 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 EMC91438.1 - 0.96 9.5 2.8 21 5.1 0.4 2.4 2 0 0 2 2 2 0 Dynamin family Sod_Fe_C PF02777.18 EMC91439.1 - 3.9e-15 55.9 0.0 3.4e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMC91439.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain VirE3 PF06661.11 EMC91439.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 VirE3 Cnd2 PF05786.14 EMC91440.1 - 2.1e-286 952.6 1.2 2.6e-286 952.3 1.2 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EMC91440.1 - 0.022 15.0 0.0 0.076 13.2 0.0 1.9 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Na_Ca_ex PF01699.24 EMC91441.1 - 6.2e-50 169.1 47.0 2.3e-29 102.3 18.3 3.1 4 0 0 4 4 4 2 Sodium/calcium exchanger protein MAP17 PF15807.5 EMC91441.1 - 4.1 7.7 4.1 0.99 9.6 0.1 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4267 PF14087.6 EMC91442.1 - 2.2e-18 66.3 3.8 2.8e-18 66.0 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) PglL_A PF15864.5 EMC91442.1 - 8.8 6.2 8.4 14 5.5 0.8 3.3 3 0 0 3 3 3 0 Protein glycosylation ligase G-patch PF01585.23 EMC91443.1 - 3.2e-05 23.7 0.0 0.00032 20.5 0.0 2.7 2 1 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EMC91443.1 - 0.079 13.1 1.6 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 G-patch domain LAP1C PF05609.12 EMC91443.1 - 2.1 7.3 17.8 2.9 6.9 17.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 EMC91443.1 - 6 3.9 12.7 7.1 3.6 12.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Acetyltransf_3 PF13302.7 EMC91444.1 - 5.1e-19 69.3 0.0 6.8e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMC91444.1 - 4e-12 46.5 0.0 1.2e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC91444.1 - 1.5e-11 44.6 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC91444.1 - 9.6e-08 32.3 0.0 1.6e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC91444.1 - 3.2e-07 30.3 0.0 4.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMC91444.1 - 1.2e-06 28.3 0.0 3.8e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC91444.1 - 0.00074 19.4 0.1 0.0013 18.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Glyco_hydro_10 PF00331.20 EMC91445.1 - 5.9e-80 268.8 2.1 6.9e-80 268.6 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GST_N_3 PF13417.6 EMC91446.1 - 3e-17 62.8 0.0 5.4e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMC91446.1 - 1.6e-11 44.4 0.0 5.8e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMC91446.1 - 5.2e-11 42.7 0.0 4.3e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMC91446.1 - 6.9e-09 35.6 0.1 1.3e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC91446.1 - 7.1e-09 35.8 0.0 1.5e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMC91446.1 - 1e-05 25.7 0.0 2.2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMC91446.1 - 1.9e-05 25.2 0.0 3.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EMC91446.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RSN1_7TM PF02714.15 EMC91447.1 - 2.8e-82 276.1 16.3 2.8e-82 276.1 16.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMC91447.1 - 5.6e-39 133.4 2.4 5.6e-39 133.4 2.4 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMC91447.1 - 8.8e-24 84.7 0.0 1.4e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EMC91447.1 - 5e-18 65.1 0.1 1.1e-17 64.0 0.1 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter 7tm_1 PF00001.21 EMC91447.1 - 0.084 12.2 0.8 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) E1-E2_ATPase PF00122.20 EMC91448.1 - 1.8e-53 180.8 4.4 5.6e-52 175.9 0.7 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMC91448.1 - 8.8e-47 159.2 5.7 8.8e-47 159.2 5.7 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMC91448.1 - 2.4e-22 80.3 0.4 1.1e-21 78.1 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMC91448.1 - 5.7e-21 74.4 0.0 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMC91448.1 - 2.5e-16 59.1 0.0 7e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMC91448.1 - 1e-08 35.3 1.7 1.8e-06 27.9 0.8 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMC91448.1 - 2.9e-07 31.1 0.0 1.2e-06 29.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad60-SLD PF11976.8 EMC91451.1 - 0.026 14.3 0.0 3.4 7.6 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like 14-3-3 PF00244.20 EMC91452.1 - 1e-107 358.7 0.8 1.2e-107 358.5 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 EMC91452.1 - 0.0038 15.7 0.9 0.0063 15.0 0.9 1.3 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP5 MFS_1 PF07690.16 EMC91453.1 - 2.3e-37 128.7 54.0 2.3e-37 128.7 54.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Ndc1_Nup PF09531.10 EMC91453.1 - 4.7 5.8 7.7 10 4.6 7.7 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DEAD PF00270.29 EMC91455.1 - 5.3e-45 153.3 0.0 5.7e-44 150.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC91455.1 - 4.4e-30 104.3 0.1 6.3e-29 100.6 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC91455.1 - 0.0027 17.7 0.0 0.0061 16.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRAI PF00697.22 EMC91455.1 - 0.03 14.1 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Rad60-SLD PF11976.8 EMC91456.1 - 0.0016 18.2 0.0 0.02 14.7 0.0 2.8 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EMC91456.1 - 0.016 14.9 0.0 0.061 13.1 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family DUF1640 PF07798.11 EMC91457.1 - 4e-57 193.1 7.8 4.8e-57 192.8 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LMBR1 PF04791.16 EMC91457.1 - 0.00021 20.3 1.1 0.00022 20.3 1.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein XhlA PF10779.9 EMC91457.1 - 0.98 9.7 4.8 0.19 12.0 0.5 2.1 3 0 0 3 3 3 0 Haemolysin XhlA DUF3602 PF12223.8 EMC91458.1 - 1.6e-18 67.1 6.8 6.9e-18 65.0 1.5 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) GHMP_kinases_N PF00288.26 EMC91459.1 - 1.7e-14 53.8 1.1 4.1e-14 52.6 0.1 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMC91459.1 - 1.3e-09 38.3 0.1 3.3e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EMC91459.1 - 0.011 15.2 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature zf-SCNM1 PF15803.5 EMC91460.1 - 0.081 12.6 3.2 0.15 11.8 1.8 2.2 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 Prenyltrans PF00432.21 EMC91461.1 - 1.1e-60 201.0 12.8 3.5e-12 45.8 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EMC91461.1 - 0.00011 21.5 0.0 3.1 6.8 0.0 4.3 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain RhoGAP PF00620.27 EMC91462.1 - 9.7e-29 100.2 0.0 1.5e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF3915 PF13054.6 EMC91462.1 - 0.052 13.5 2.7 0.2 11.6 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Rrn6 PF10214.9 EMC91462.1 - 0.17 10.4 6.1 0.24 9.9 6.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Mitofilin PF09731.9 EMC91462.1 - 3.7 6.3 13.8 5.6 5.7 13.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SnoaL_2 PF12680.7 EMC91463.1 - 6.2e-06 26.8 0.5 9.9e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 EMC91463.1 - 0.0057 16.5 0.1 0.033 14.0 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase ADH_zinc_N PF00107.26 EMC91465.1 - 9.9e-22 77.3 0.3 9.9e-22 77.3 0.3 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC91465.1 - 7.1e-14 51.6 3.3 1.4e-13 50.7 3.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_32 PF13679.6 EMC91465.1 - 0.005 16.8 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EMC91465.1 - 0.08 14.0 0.9 0.15 13.2 0.3 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Pam17 PF08566.10 EMC91467.1 - 2.9e-56 189.8 0.0 3.3e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 UCR_Fe-S_N PF10399.9 EMC91467.1 - 0.014 14.7 0.2 0.014 14.7 0.2 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Pex24p PF06398.11 EMC91468.1 - 0.18 10.8 0.0 0.2 10.6 0.0 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Patatin PF01734.22 EMC91470.1 - 9.3e-22 78.2 0.0 1.5e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase MFS_1 PF07690.16 EMC91471.1 - 1.7e-31 109.4 29.4 2.9e-31 108.7 29.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SIS PF01380.22 EMC91474.1 - 1.1e-56 190.3 0.1 9e-31 106.4 0.0 2.2 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EMC91474.1 - 2.2e-17 63.5 0.0 4.5e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EMC91474.1 - 2.4e-11 43.6 0.0 6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EMC91474.1 - 0.00071 18.6 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 EMC91474.1 - 0.14 12.1 0.1 1 9.4 0.0 2.5 3 1 1 4 4 4 0 SIS domain CFEM PF05730.11 EMC91475.1 - 1.3e-09 38.0 11.0 1.3e-09 38.0 11.0 2.3 2 1 0 2 2 2 1 CFEM domain Lactamase_B_2 PF12706.7 EMC91476.1 - 2.1e-15 56.8 0.1 4.5e-15 55.7 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMC91476.1 - 1.5e-12 47.7 0.2 6.6e-12 45.6 0.2 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMC91476.1 - 0.0027 17.8 6.7 0.042 13.8 4.7 2.8 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily Ribosomal_L38e PF01781.18 EMC91477.1 - 8.5e-34 115.5 2.6 1.1e-33 115.1 2.6 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family Mtr2 PF10429.9 EMC91478.1 - 0.00031 20.7 0.0 0.001 19.0 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.20 EMC91478.1 - 0.00066 20.2 0.2 0.011 16.3 0.2 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain AAA_23 PF13476.6 EMC91479.1 - 0.08 13.4 4.1 0.15 12.6 4.1 1.5 1 0 0 1 1 1 0 AAA domain Ish1 PF10281.9 EMC91480.1 - 1.1e-06 28.8 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein Glyco_hydro_47 PF01532.20 EMC91481.1 - 3.7e-166 553.6 0.3 4.9e-166 553.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FA_desaturase PF00487.24 EMC91481.1 - 2 8.2 5.5 15 5.3 0.2 2.3 2 0 0 2 2 2 0 Fatty acid desaturase Ferritin_2 PF13668.6 EMC91483.1 - 3.4e-06 27.3 0.2 7.3e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Ferritin-like domain HET PF06985.11 EMC91485.1 - 3.9e-13 50.0 4.6 2.6e-12 47.3 4.6 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Proteasome PF00227.26 EMC91486.1 - 3.6e-28 98.3 0.1 7e-28 97.4 0.1 1.6 1 1 0 1 1 1 1 Proteasome subunit MDM31_MDM32 PF08118.11 EMC91487.1 - 3.7e-236 784.9 0.2 3.7e-235 781.5 0.2 1.9 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_8 PF17903.1 EMC91488.1 - 1.7e-08 34.4 0.0 3.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EMC91488.1 - 0.0063 16.3 0.3 0.014 15.2 0.3 1.6 1 0 0 1 1 1 1 KH domain Abhydrolase_5 PF12695.7 EMC91490.1 - 0.00087 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EMC91490.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Ubie_methyltran PF01209.18 EMC91491.1 - 0.00028 20.3 0.0 0.0054 16.1 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EMC91491.1 - 0.0068 17.0 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC91491.1 - 0.0097 16.6 0.0 0.021 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_28 PF00295.17 EMC91492.1 - 3.2e-42 144.8 1.8 2.1e-41 142.1 1.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 SpmSyn_N PF17950.1 EMC91493.1 - 0.083 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal Toxin_6 PF05453.12 EMC91494.1 - 0.12 12.9 3.4 0.26 11.8 3.4 1.6 1 0 0 1 1 1 0 BmTXKS1/BmP02 toxin family CN_hydrolase PF00795.22 EMC91495.1 - 6.8e-28 97.7 0.0 9.1e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EMC91495.1 - 5.5e-24 84.6 0.0 1.6e-23 83.1 0.0 1.7 1 1 0 1 1 1 1 NAD synthase CPSase_L_D2 PF02786.17 EMC91496.1 - 1.9e-81 272.6 0.0 2.9e-81 272.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EMC91496.1 - 7.3e-70 234.8 0.1 1.2e-69 234.0 0.1 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EMC91496.1 - 6.4e-37 126.5 0.0 1.3e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EMC91496.1 - 1.5e-30 105.4 0.0 4.1e-30 104.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EMC91496.1 - 1.3e-29 103.5 0.0 3.8e-29 102.1 0.0 1.7 2 0 0 2 2 2 1 HMGL-like Biotin_lipoyl PF00364.22 EMC91496.1 - 7.8e-18 64.1 5.7 9.8e-18 63.8 4.1 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EMC91496.1 - 2.1e-10 40.5 0.0 4.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EMC91496.1 - 3.1e-09 36.5 1.3 1.4e-06 28.0 0.4 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EMC91496.1 - 7.8e-07 28.8 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EMC91496.1 - 3.9e-05 23.8 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EMC91496.1 - 0.00033 20.3 0.1 0.0042 16.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 EMC91496.1 - 0.00035 21.2 0.3 0.54 11.0 0.1 3.0 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EMC91496.1 - 0.0025 17.0 0.3 0.17 11.1 0.1 2.6 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GARS_A PF01071.19 EMC91496.1 - 0.0097 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EMC91496.1 - 0.011 15.4 0.0 0.061 12.9 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain GCV_H PF01597.19 EMC91496.1 - 0.16 11.9 0.8 0.68 9.8 0.7 2.1 1 1 1 2 2 2 0 Glycine cleavage H-protein RnfC_N PF13375.6 EMC91496.1 - 0.16 12.0 0.9 0.95 9.5 0.9 2.2 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain ATPgrasp_Ter PF15632.6 EMC91496.1 - 0.17 11.6 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon CMAS PF02353.20 EMC91497.1 - 2.4e-61 207.5 0.1 2.9e-61 207.2 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EMC91497.1 - 5.6e-11 42.6 0.0 9.9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC91497.1 - 7.5e-09 36.2 0.0 1.4e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC91497.1 - 8.3e-09 36.0 0.0 1.5e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC91497.1 - 0.0012 19.5 0.0 0.0026 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMC91497.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EMC91497.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 EMC91497.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 EMC91497.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 WD40 PF00400.32 EMC91498.1 - 2e-57 189.8 29.5 2.4e-10 40.8 0.6 9.2 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC91498.1 - 3.5e-21 75.3 1.5 0.0026 18.0 0.0 6.3 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMC91498.1 - 6.8e-07 28.5 1.2 0.42 9.5 0.0 4.8 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EMC91498.1 - 5.9e-06 25.2 1.8 0.14 10.8 0.3 3.6 3 1 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EMC91498.1 - 4.5e-05 23.4 0.0 0.047 13.6 0.0 3.8 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 EMC91498.1 - 0.00056 20.4 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.6 EMC91498.1 - 0.017 14.5 0.1 4.4 6.6 0.0 3.3 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EMC91498.1 - 0.085 12.8 1.6 17 5.5 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 EMC91498.1 - 0.13 11.0 0.0 2.5 6.8 0.0 2.4 1 1 0 1 1 1 0 Nup133 N terminal like DUF1652 PF07865.11 EMC91498.1 - 0.13 12.1 0.0 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) TFIIIC_delta PF12657.7 EMC91498.1 - 1.3 8.9 3.5 18 5.2 0.2 3.8 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term MutS_V PF00488.21 EMC91499.1 - 7.4e-64 215.2 0.7 1.3e-63 214.5 0.7 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMC91499.1 - 7.9e-31 107.8 5.0 7.9e-31 107.8 5.0 2.2 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EMC91499.1 - 5.3e-11 43.0 0.2 2e-10 41.0 0.2 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EMC91499.1 - 5.5e-08 33.0 0.3 5.5e-08 33.0 0.3 2.3 2 1 1 3 3 3 1 MutS family domain IV AAA_27 PF13514.6 EMC91499.1 - 0.0074 15.9 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Y_phosphatase3 PF13350.6 EMC91500.1 - 3.9e-46 157.9 0.0 5.4e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EMC91500.1 - 1.4e-09 37.7 0.1 7.5e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EMC91500.1 - 0.00027 20.6 0.0 0.00069 19.2 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 EMC91500.1 - 0.00087 19.1 0.0 0.0045 16.8 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EMC91500.1 - 0.021 13.7 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Init_tRNA_PT PF04179.12 EMC91500.1 - 0.06 13.6 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Kv2channel PF03521.14 EMC91500.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel Eisosome1 PF12757.7 EMC91501.1 - 2.5e-40 137.6 19.6 2.5e-40 137.6 19.6 3.6 4 0 0 4 4 4 1 Eisosome protein 1 Robl_LC7 PF03259.17 EMC91501.1 - 0.27 11.0 1.0 5.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Roadblock/LC7 domain DNA_pol3_a_NII PF11490.8 EMC91501.1 - 2.9 7.8 9.2 10 6.0 9.2 1.9 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II PCI PF01399.27 EMC91502.1 - 5.5e-14 52.6 0.3 1.3e-13 51.3 0.1 1.8 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 EMC91502.1 - 3.5e-13 49.0 2.3 9.3e-13 47.6 2.3 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix DUF2508 PF10704.9 EMC91502.1 - 0.093 12.9 0.2 16 5.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) REV PF00424.18 EMC91502.1 - 2.1 8.4 10.6 0.46 10.5 4.5 3.0 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) DNA_pol_E_B PF04042.16 EMC91503.1 - 2.1e-44 151.4 0.0 3.1e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EMC91503.1 - 5.5e-37 126.8 0.0 8.7e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DUF2277 PF10041.9 EMC91503.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) Dsl1_C PF11989.8 EMC91504.1 - 5.1e-07 29.6 0.7 1e-06 28.6 0.1 1.9 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.13 EMC91504.1 - 0.00098 17.8 0.1 0.0015 17.1 0.1 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Tropomyosin_1 PF12718.7 EMC91504.1 - 0.016 15.3 4.7 0.016 15.3 4.7 2.8 3 1 0 3 3 3 0 Tropomyosin like Hrs_helical PF12210.8 EMC91504.1 - 0.11 13.1 2.1 10 6.7 0.0 3.0 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate IL28A PF15177.6 EMC91504.1 - 0.22 11.3 1.1 0.74 9.6 1.1 1.9 1 0 0 1 1 1 0 Interleukin-28A AAA_13 PF13166.6 EMC91504.1 - 1.1 7.8 3.9 1.7 7.2 3.9 1.2 1 0 0 1 1 1 0 AAA domain LUC7 PF03194.15 EMC91504.1 - 2.3 7.8 6.1 4.6 6.8 4.2 2.2 2 1 0 2 2 2 0 LUC7 N_terminus Macoilin PF09726.9 EMC91504.1 - 6.2 5.2 6.8 20 3.5 5.4 2.0 2 0 0 2 2 2 0 Macoilin family Acetyltransf_1 PF00583.25 EMC91505.1 - 4.5e-06 26.9 0.0 7.8e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC91505.1 - 1e-05 25.9 0.0 2.2e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMC91505.1 - 0.00024 21.2 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 EMC91505.1 - 0.00096 19.1 0.0 0.0024 17.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC91505.1 - 0.02 15.0 0.0 0.088 12.9 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain HMGL-like PF00682.19 EMC91506.1 - 1.2e-78 264.3 1.9 2e-78 263.6 1.9 1.3 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.20 EMC91506.1 - 0.048 12.5 0.0 9.2 5.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Phage_holin_6_1 PF09682.10 EMC91506.1 - 0.66 10.4 3.4 21 5.6 0.1 3.6 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) MPC PF03650.13 EMC91507.1 - 8.4e-24 83.8 0.0 1.2e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF5610 PF18433.1 EMC91507.1 - 0.05 14.1 1.8 0.49 10.9 1.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5610) DUF883 PF05957.13 EMC91507.1 - 0.12 13.0 1.0 0.17 12.5 1.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) CAP PF00188.26 EMC91508.1 - 2.2e-07 31.8 0.5 3.6e-07 31.1 0.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mucin PF01456.17 EMC91508.1 - 0.33 10.9 18.6 0.41 10.6 18.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_L5_C PF00673.21 EMC91509.1 - 6.1e-22 77.6 0.0 8.7e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EMC91509.1 - 9.7e-19 67.5 0.1 2.7e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 EMC91510.1 - 7.3e-17 60.8 0.0 1.1e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain CMD PF02627.20 EMC91511.1 - 0.02 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family DUF2757 PF10955.8 EMC91511.1 - 0.079 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) SWIB PF02201.18 EMC91512.1 - 3.2e-29 100.6 0.1 5.9e-29 99.8 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EMC91512.1 - 1.1e-13 50.8 0.7 1.1e-13 50.8 0.7 2.1 2 0 0 2 2 2 1 DEK C terminal domain SRP-alpha_N PF04086.13 EMC91512.1 - 0.69 9.8 13.8 0.95 9.3 13.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.16 EMC91513.1 - 6.6e-19 68.0 54.8 2.3e-17 63.0 45.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PAF-AH_p_II PF03403.13 EMC91514.1 - 2e-33 115.5 0.0 2.8e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 EMC91514.1 - 0.0026 18.4 0.0 0.0072 16.9 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EMC91514.1 - 0.0059 15.5 0.0 0.022 13.7 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EMC91514.1 - 0.043 13.1 0.7 2 7.6 0.0 2.5 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EMC91514.1 - 0.072 12.9 0.0 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold kleA_kleC PF17383.2 EMC91516.1 - 0.039 14.3 1.8 0.039 14.3 1.8 1.8 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A PAT1 PF09770.9 EMC91517.1 - 1.3e-298 993.1 41.9 9.1e-297 987.0 41.9 2.1 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.16 EMC91518.1 - 3.7e-128 427.3 10.6 4.7e-128 427.0 10.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAP1 PF08601.10 EMC91518.1 - 0.12 12.0 4.7 0.47 10.1 4.1 1.9 2 0 0 2 2 2 0 Transcription factor PAP1 EGF_3 PF12947.7 EMC91518.1 - 0.17 12.1 2.1 0.35 11.1 2.1 1.5 1 0 0 1 1 1 0 EGF domain TMEM61 PF15105.6 EMC91519.1 - 0.073 12.9 0.3 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 TMEM61 protein family F-box PF00646.33 EMC91520.1 - 3.7e-07 29.9 0.5 3.8e-06 26.6 0.3 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EMC91520.1 - 0.00066 19.5 0.2 0.002 18.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like GCP_N_terminal PF17681.1 EMC91522.1 - 2e-28 99.9 0.1 3.6e-28 99.1 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EMC91522.1 - 3e-26 92.6 1.6 5e-26 91.9 1.6 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Mito_carr PF00153.27 EMC91523.1 - 2.7e-68 226.0 6.8 1.1e-23 82.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EMC91523.1 - 4e-21 72.9 0.6 5.8e-05 22.3 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EMC91523.1 - 1.1e-19 70.7 2.1 7.9e-09 35.8 0.8 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EMC91523.1 - 8.3e-17 59.6 4.4 0.00039 20.1 0.8 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EMC91523.1 - 2.7e-16 58.2 4.2 0.00025 20.4 0.2 3.4 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 EMC91523.1 - 4.5e-10 39.9 0.1 0.0012 19.1 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EMC91523.1 - 1.8e-06 27.7 3.4 0.0037 17.1 0.1 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EMC91523.1 - 0.0007 19.5 1.8 0.91 9.5 0.2 3.3 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EMC91523.1 - 0.024 14.5 2.7 7.5 6.5 0.1 3.2 3 1 0 3 3 3 0 EF hand Response_reg PF00072.24 EMC91524.1 - 4.5e-22 78.3 0.1 1.6e-21 76.6 0.1 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EMC91524.1 - 6.2e-21 75.0 0.0 1.1e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMC91524.1 - 8.6e-09 35.3 0.3 5.3e-08 32.8 0.2 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EMC91524.1 - 2.6e-06 27.6 0.0 1.3e-05 25.4 0.0 2.2 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 EMC91524.1 - 0.00022 21.2 0.0 0.00075 19.5 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EMC91524.1 - 0.00032 20.7 0.0 0.00088 19.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.6 EMC91524.1 - 0.00051 20.3 0.0 0.014 15.7 0.0 3.1 3 1 0 3 3 3 1 GAF domain PAS_4 PF08448.10 EMC91524.1 - 0.0024 18.1 0.0 0.66 10.3 0.0 3.2 2 1 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 EMC91524.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3112 PF11309.8 EMC91525.1 - 2e-12 47.0 10.9 1.7e-09 37.4 0.8 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) zf-ZPR1 PF03367.13 EMC91527.1 - 7.6e-110 363.9 0.0 1.1e-56 191.2 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.10 EMC91527.1 - 1 9.5 7.6 14 5.9 0.1 4.1 4 0 0 4 4 4 0 Zinc ribbon domain Rpr2 PF04032.16 EMC91528.1 - 5.8e-11 42.5 0.8 5.8e-11 42.5 0.8 1.5 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 EMC91528.1 - 0.13 12.3 1.6 0.34 11.0 1.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon tRNA_int_end_N2 PF12928.7 EMC91529.1 - 6.1e-24 84.0 0.0 1.2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EMC91529.1 - 0.0083 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain DBR1 PF05011.13 EMC91530.1 - 8.7e-39 133.1 0.0 1.3e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain HET PF06985.11 EMC91533.1 - 3.5e-05 24.2 0.7 0.01 16.2 0.0 2.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Toxin_18 PF08087.11 EMC91533.1 - 0.13 12.3 0.9 0.21 11.6 0.9 1.3 1 0 0 1 1 1 0 Conotoxin O-superfamily TPR_14 PF13428.6 EMC91534.1 - 1.7e-12 47.0 22.6 0.44 11.5 0.0 11.3 11 2 2 13 13 11 3 Tetratricopeptide repeat Suf PF05843.14 EMC91534.1 - 1.4e-09 38.4 11.3 0.083 12.9 0.1 6.3 4 2 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EMC91534.1 - 2.5e-09 36.6 4.0 0.022 14.9 0.0 6.2 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMC91534.1 - 2.7e-07 30.8 6.9 3.6 8.0 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMC91534.1 - 7.5e-06 25.4 5.7 9.9e-05 21.7 0.8 3.9 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMC91534.1 - 3.4e-05 24.3 5.4 1.4 9.5 0.0 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EMC91534.1 - 0.00051 20.0 16.5 1.7 8.7 0.0 7.1 7 2 2 9 9 9 3 Mad3/BUB1 homology region 1 RPN7 PF10602.9 EMC91534.1 - 0.0061 16.3 0.1 0.13 11.9 0.0 2.9 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 EMC91534.1 - 0.013 15.6 15.1 0.15 12.2 0.0 7.0 10 0 0 10 10 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMC91534.1 - 0.024 14.5 12.6 0.21 11.5 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EMC91534.1 - 0.085 12.0 15.0 0.73 8.9 0.2 5.9 2 2 2 5 5 5 0 NRDE-2, necessary for RNA interference SHNi-TPR PF10516.9 EMC91534.1 - 0.095 12.2 0.8 0.89 9.1 0.0 2.8 3 0 0 3 3 3 0 SHNi-TPR TPR_6 PF13174.6 EMC91534.1 - 0.11 13.1 7.4 13 6.7 0.0 5.7 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMC91534.1 - 0.2 12.1 6.4 11 6.7 0.0 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMC91534.1 - 0.4 11.4 3.1 56 4.8 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMC91534.1 - 0.57 10.3 6.5 1.7 8.9 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMC91534.1 - 3.2 8.5 10.1 4.1 8.1 0.0 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Pantoate_ligase PF02569.15 EMC91535.1 - 2e-93 312.4 0.0 2.4e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Sugar_tr PF00083.24 EMC91537.1 - 4.3e-88 296.2 22.0 5.2e-88 295.9 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC91537.1 - 8.7e-22 77.5 40.8 3e-15 56.0 18.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMC91537.1 - 0.0022 16.4 11.7 0.64 8.2 0.1 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EMC91538.1 - 1.9e-96 323.7 22.0 2.3e-96 323.4 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC91538.1 - 1.2e-25 90.2 23.6 1.3e-24 86.8 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NaeI PF09126.10 EMC91538.1 - 0.0014 17.9 0.0 0.002 17.4 0.0 1.1 1 0 0 1 1 1 1 Restriction endonuclease NaeI Glyco_hydro_72 PF03198.14 EMC91539.1 - 6.8e-111 370.5 0.5 8.6e-111 370.2 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EMC91539.1 - 0.022 14.2 0.0 1.2 8.5 0.0 2.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Hamartin PF04388.12 EMC91540.1 - 2.5e-22 79.4 31.8 1.9e-20 73.2 31.8 3.9 1 1 0 1 1 1 1 Hamartin protein YabA PF06156.13 EMC91540.1 - 0.26 11.9 0.0 0.26 11.9 0.0 4.7 2 1 3 5 5 5 0 Initiation control protein YabA GTP-bdg_N PF13167.6 EMC91540.1 - 0.64 10.7 3.8 2.5 8.9 0.9 2.6 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal Asp-B-Hydro_N PF05279.11 EMC91540.1 - 5.8 6.9 17.9 13 5.8 17.9 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribonuclease_3 PF00636.26 EMC91542.1 - 1.3e-38 131.8 0.0 2e-18 66.9 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 EMC91542.1 - 4.5e-24 84.4 0.0 3.6e-23 81.5 0.0 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 EMC91542.1 - 4.7e-23 81.7 0.0 2.1e-11 44.1 0.0 3.1 2 1 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 EMC91542.1 - 8e-16 58.4 0.0 2.2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC91542.1 - 4.5e-13 49.6 0.0 1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMC91542.1 - 5.5e-12 45.8 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMC91542.1 - 0.016 15.5 0.0 0.062 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain dsrm PF00035.26 EMC91542.1 - 0.02 15.6 0.0 16 6.3 0.0 2.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif TAP42 PF04177.12 EMC91543.1 - 4.9e-106 354.5 4.3 5.6e-106 354.3 4.3 1.0 1 0 0 1 1 1 1 TAP42-like family Terminase_4 PF05119.12 EMC91543.1 - 0.057 13.9 0.1 0.13 12.7 0.1 1.7 1 0 0 1 1 1 0 Phage terminase, small subunit PAPS_reduct PF01507.19 EMC91544.1 - 7.4e-28 97.8 0.0 4.3e-19 69.2 0.0 2.6 2 1 1 3 3 3 2 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.25 EMC91545.1 - 9.1e-22 77.7 0.0 1.5e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EMC91545.1 - 1.4e-10 41.5 7.5 4.2e-05 24.2 0.5 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT PF02985.22 EMC91545.1 - 3.4e-06 26.9 6.4 0.029 14.6 0.1 6.2 6 0 0 6 6 6 1 HEAT repeat Kinase-like PF14531.6 EMC91545.1 - 2.4e-05 23.8 0.0 4.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 EMC91545.1 - 3.2e-05 23.3 0.0 5.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 EMC91545.1 - 0.0032 17.7 0.1 0.36 11.2 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 EMC91545.1 - 0.0061 16.9 5.1 0.1 13.0 0.0 4.1 4 1 1 5 5 5 1 HEAT repeats DUF4051 PF13260.6 EMC91545.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Citrate_synt PF00285.21 EMC91547.1 - 2.5e-21 76.1 0.0 2.2e-17 63.2 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EMC91547.1 - 2.2e-13 50.7 0.0 9.5e-13 48.7 0.0 2.1 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 EMC91547.1 - 0.006 16.4 0.4 0.11 12.3 0.1 2.3 1 1 1 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 EMC91547.1 - 0.026 14.3 0.8 1.2 9.0 0.0 3.1 2 1 1 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 EMC91549.1 - 1.1e-86 288.9 0.0 1.5e-86 288.4 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EMC91549.1 - 2.7e-08 33.6 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 EMC91549.1 - 0.12 10.5 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) 3HCDH_N PF02737.18 EMC91550.1 - 1.8e-33 116.0 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EMC91550.1 - 1e-18 67.7 0.0 2.2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 EMC91550.1 - 0.0098 15.3 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EMC91550.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SGL PF08450.12 EMC91550.1 - 0.016 14.8 0.2 2.3 7.7 0.0 2.7 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_b PF00058.17 EMC91550.1 - 0.017 15.6 0.6 4.2 7.9 0.2 3.6 3 1 0 3 3 3 0 Low-density lipoprotein receptor repeat class B F420_oxidored PF03807.17 EMC91550.1 - 0.021 15.4 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EMC91550.1 - 0.031 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_1 PF00175.21 EMC91551.1 - 4e-29 101.5 0.0 6.7e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMC91551.1 - 4.9e-27 94.2 0.0 8.3e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EMC91551.1 - 2.3e-18 66.1 0.1 5e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EMC91551.1 - 1.5e-05 25.1 0.0 0.0029 17.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EMC91551.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain p450 PF00067.22 EMC91552.1 - 7.4e-70 236.0 0.0 9.1e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_ribbon_17 PF17120.5 EMC91553.1 - 0.0019 17.7 2.3 0.0019 17.7 2.3 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EMC91553.1 - 0.0052 16.6 19.6 0.094 12.6 8.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC91553.1 - 0.044 13.7 19.7 0.21 11.5 3.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC91553.1 - 0.14 12.5 19.0 0.76 10.2 3.4 2.5 2 0 0 2 2 2 0 Ring finger domain Zn_Tnp_IS91 PF14319.6 EMC91553.1 - 0.39 10.8 14.7 0.25 11.4 2.5 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_5 PF14634.6 EMC91553.1 - 7 6.7 19.4 7.1 6.7 5.7 2.8 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMC91553.1 - 7.5 6.7 14.7 7 6.8 2.1 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Siva PF05458.12 EMC91553.1 - 8.4 6.0 17.7 4.7 6.9 6.0 2.5 2 0 0 2 2 2 0 Cd27 binding protein (Siva) RNA_pol PF00940.19 EMC91554.1 - 1.7e-184 613.5 0.0 2.4e-184 613.0 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EMC91554.1 - 1.7e-88 297.3 7.1 2.8e-88 296.5 1.5 2.5 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal MBF1 PF08523.10 EMC91554.1 - 4.3 7.9 8.7 7 7.2 2.0 3.1 3 0 0 3 3 3 0 Multiprotein bridging factor 1 BCIP PF13862.6 EMC91555.1 - 4.1e-68 229.2 0.1 5.2e-68 228.9 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CAMP_factor PF07373.11 EMC91556.1 - 0.011 15.4 0.9 0.025 14.2 0.9 1.7 1 0 0 1 1 1 0 CAMP factor (Cfa) IMS_C PF11799.8 EMC91556.1 - 0.083 13.6 2.3 0.52 11.0 0.1 2.7 3 0 0 3 3 3 0 impB/mucB/samB family C-terminal domain DivIVA PF05103.13 EMC91556.1 - 1.5 8.9 12.4 0.22 11.6 0.9 3.3 2 1 1 3 3 3 0 DivIVA protein MAS20 PF02064.15 EMC91557.1 - 4.1e-44 149.8 0.2 4.8e-44 149.6 0.2 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor DUF429 PF04250.13 EMC91557.1 - 0.0047 16.7 2.2 1.1 8.9 1.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF429) DUF4129 PF13559.6 EMC91557.1 - 0.0078 16.5 0.3 0.048 13.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) betaPIX_CC PF16523.5 EMC91557.1 - 0.026 14.4 1.7 0.038 13.8 1.7 1.2 1 0 0 1 1 1 0 betaPIX coiled coil ELFV_dehydrog PF00208.21 EMC91557.1 - 0.087 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Exo84_C PF16528.5 EMC91558.1 - 9.2e-52 175.8 0.0 7.1e-51 172.9 0.0 2.1 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EMC91558.1 - 8.4e-17 61.0 2.7 2.8e-16 59.4 2.7 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 EMC91558.1 - 0.086 12.6 0.1 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 COG2 PF06148.11 EMC91558.1 - 1.2 9.2 4.0 0.58 10.2 0.4 2.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 LSM PF01423.22 EMC91560.1 - 1.5e-15 56.7 0.0 1.9e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain His_Phos_2 PF00328.22 EMC91561.1 - 5.1e-12 45.8 0.2 8e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Phage_Coat_B PF05356.11 EMC91561.1 - 0.02 14.8 0.3 0.086 12.8 0.3 2.1 1 0 0 1 1 1 0 Phage Coat protein B SmpA_OmlA PF04355.13 EMC91561.1 - 0.089 12.6 0.1 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 SmpA / OmlA family Clathrin PF00637.20 EMC91562.1 - 4.2e-22 78.6 2.6 6.2e-21 74.8 0.5 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 EMC91562.1 - 7.3e-18 64.5 0.1 1.7e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EMC91562.1 - 9.5e-07 28.8 4.1 2.2e-06 27.6 4.1 1.7 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EMC91562.1 - 0.00027 20.7 5.9 0.00058 19.6 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC91562.1 - 0.0031 17.5 5.4 0.0066 16.4 5.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMC91562.1 - 0.0044 17.0 3.3 0.011 15.8 3.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EMC91562.1 - 0.0046 17.3 5.8 0.0092 16.3 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.6 EMC91562.1 - 0.012 15.3 0.3 0.049 13.3 0.3 2.1 1 0 0 1 1 1 0 TPR repeat zf-ANAPC11 PF12861.7 EMC91562.1 - 0.014 15.5 0.6 0.038 14.0 0.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_14 PF13428.6 EMC91562.1 - 0.062 14.1 1.5 5.8 8.0 0.1 3.7 3 1 0 3 3 2 0 Tetratricopeptide repeat Mcl1_mid PF12341.8 EMC91562.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region zf-rbx1 PF12678.7 EMC91562.1 - 0.099 12.9 3.4 0.23 11.8 3.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Pyr_excise PF03013.14 EMC91562.1 - 0.13 12.3 1.0 0.32 11.0 1.0 1.7 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Zn_Tnp_IS91 PF14319.6 EMC91562.1 - 0.2 11.7 1.2 0.58 10.2 1.2 1.8 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-C2H2_3 PF13878.6 EMC91562.1 - 0.3 10.9 1.8 0.38 10.6 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C3HC4 PF00097.25 EMC91562.1 - 0.36 10.7 5.9 0.74 9.7 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EMC91562.1 - 0.91 9.8 5.1 0.4 10.9 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMC91562.1 - 1.1 9.7 4.4 4.8 7.6 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PHD PF00628.29 EMC91562.1 - 1.2 9.0 4.0 2.6 8.0 4.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 EMC91562.1 - 4.5 7.5 4.9 11 6.3 4.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ANAPC3 PF12895.7 EMC91562.1 - 9.9 6.5 7.8 43 4.4 0.4 3.7 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DDHD PF02862.17 EMC91564.1 - 7e-26 91.8 0.0 4.5e-16 59.7 0.0 2.7 1 1 1 2 2 2 2 DDHD domain Abhydrolase_6 PF12697.7 EMC91564.1 - 0.0094 16.6 0.3 0.0094 16.6 0.3 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF202 PF02656.15 EMC91565.1 - 6.9e-15 55.2 1.8 6.9e-15 55.2 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2569 PF10754.9 EMC91565.1 - 0.028 14.9 1.8 0.039 14.4 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) NrsF PF06532.11 EMC91565.1 - 0.039 13.7 7.6 0.062 13.0 7.6 1.3 1 0 0 1 1 1 0 Negative regulator of sigma F CopD PF05425.13 EMC91565.1 - 0.12 12.8 6.1 0.86 10.0 3.7 2.1 2 0 0 2 2 2 0 Copper resistance protein D COX4_pro_2 PF07835.12 EMC91565.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.7 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF4231 PF14015.6 EMC91565.1 - 0.7 10.4 5.3 4.5 7.8 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Cofilin_ADF PF00241.20 EMC91566.1 - 1.6e-20 73.1 0.1 2e-20 72.8 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ras PF00071.22 EMC91567.1 - 2.7e-58 196.1 0.2 3.2e-58 195.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC91567.1 - 5.2e-19 68.6 0.0 7.9e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC91567.1 - 1.4e-07 31.2 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMC91567.1 - 1.9e-05 24.3 0.1 0.0001 21.9 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMC91567.1 - 2.2e-05 24.4 0.0 0.12 12.2 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMC91567.1 - 0.0002 21.4 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EMC91567.1 - 0.0021 18.0 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EMC91567.1 - 0.024 14.1 0.1 0.074 12.6 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B CbiA PF01656.23 EMC91567.1 - 0.12 12.5 0.1 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 EMC91567.1 - 0.14 11.4 0.1 0.29 10.3 0.1 1.5 1 1 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 EMC91567.1 - 0.17 11.6 1.2 3.5 7.3 0.2 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Ser_hydrolase PF06821.13 EMC91567.1 - 0.21 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Bac_rhamnosid6H PF17389.2 EMC91568.1 - 1.9e-125 418.7 0.3 2.4e-125 418.3 0.3 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EMC91568.1 - 2.4e-50 170.7 0.1 8.4e-50 168.9 0.0 1.9 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 EMC91568.1 - 6.1e-28 96.8 0.0 1.4e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 EMC91568.1 - 1.6e-16 59.8 0.9 2.1e-10 40.2 0.1 3.4 3 0 0 3 3 3 2 Bacterial alpha-L-rhamnosidase C-terminal domain Sugar_tr PF00083.24 EMC91569.1 - 2.4e-61 208.0 27.6 2.8e-61 207.8 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC91569.1 - 9.6e-16 57.6 33.6 9.6e-16 57.6 33.6 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Fip1 PF05182.13 EMC91571.1 - 2e-18 65.6 2.0 3.3e-18 64.9 2.0 1.3 1 0 0 1 1 1 1 Fip1 motif YL1 PF05764.13 EMC91571.1 - 0.1 12.7 4.6 0.14 12.3 4.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nucleoporin_FG PF13634.6 EMC91572.1 - 5.1e-27 94.5 101.7 1.5e-13 51.4 35.4 3.5 1 1 2 3 3 3 3 Nucleoporin FG repeat region Ribosomal_L26 PF16906.5 EMC91574.1 - 8.1e-36 122.4 4.1 1.1e-35 122.0 4.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EMC91574.1 - 1.4e-06 28.0 1.4 1.4e-06 28.0 1.4 2.0 2 0 0 2 2 2 1 KOW motif DUF1223 PF06764.11 EMC91574.1 - 0.012 15.6 0.2 0.015 15.3 0.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) Ost4 PF10215.9 EMC91577.1 - 1.4e-19 69.6 1.9 1.7e-19 69.3 1.9 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase DFRP_C PF16543.5 EMC91578.1 - 1.2e-26 93.0 7.2 1.2e-26 93.0 7.2 4.0 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 EMC91578.1 - 8e-06 26.5 13.0 1.6e-05 25.6 2.6 3.4 3 2 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 EMC91578.1 - 2.3e-05 24.1 10.2 0.00017 21.3 3.0 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 EMC91578.1 - 0.00019 21.2 1.5 0.00019 21.2 1.5 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cwf_Cwc_15 PF04889.12 EMC91578.1 - 0.00087 19.1 11.6 0.00087 19.1 11.6 2.8 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein zf-CCCH_3 PF15663.5 EMC91578.1 - 0.0017 18.5 0.2 0.26 11.5 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 EMC91578.1 - 0.0023 17.9 7.7 0.0023 17.9 7.7 3.2 4 0 0 4 4 4 1 Zinc finger domain NT-C2 PF10358.9 EMC91578.1 - 0.2 11.4 2.2 0.71 9.6 0.4 2.5 2 1 1 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins zf-CCCH_2 PF14608.6 EMC91578.1 - 2.4 8.7 17.4 1.4 9.5 6.0 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-TRAF PF02176.18 EMC91581.1 - 1.5e-08 35.2 14.4 0.0029 18.2 4.0 4.1 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4 PF00097.25 EMC91581.1 - 4.2e-07 29.7 11.3 4.2e-07 29.7 11.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC91581.1 - 5.3e-07 29.9 13.4 5.3e-07 29.9 13.4 3.2 2 1 1 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EMC91581.1 - 1.4e-06 28.3 12.8 1.4e-06 28.3 12.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMC91581.1 - 1.2e-05 25.1 10.8 1.2e-05 25.1 10.8 2.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMC91581.1 - 2.2e-05 24.2 13.9 2.2e-05 24.2 13.9 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMC91581.1 - 0.00015 21.6 11.0 0.00015 21.6 11.0 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMC91581.1 - 0.0023 18.2 8.5 0.0023 18.2 8.5 3.2 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EMC91581.1 - 0.0027 17.7 5.8 0.0027 17.7 5.8 2.6 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EMC91581.1 - 0.011 15.6 6.9 0.015 15.1 5.4 2.1 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 EMC91581.1 - 0.014 15.3 7.9 0.014 15.3 7.9 3.2 1 1 2 3 3 3 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EMC91581.1 - 0.016 15.4 13.6 0.016 15.4 13.6 3.0 4 0 0 4 4 2 0 zinc finger of C3HC4-type, RING ANAPC4 PF12896.7 EMC91581.1 - 0.043 13.3 0.2 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 zf-TRAF_2 PF15965.5 EMC91581.1 - 2.6 8.6 24.3 5.3 7.6 6.7 3.6 1 1 2 3 3 3 0 TRAF-like zinc-finger DUF92 PF01940.16 EMC91582.1 - 4.1e-77 258.8 9.1 4.9e-77 258.5 9.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF5489 PF17592.2 EMC91582.1 - 0.014 15.9 2.0 0.014 15.9 2.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5489) CENP-T_C PF15511.6 EMC91583.1 - 5e-06 26.6 0.0 6.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EMC91583.1 - 0.00014 22.1 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 EMC91583.1 - 0.01 16.0 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Histone PF00125.24 EMC91583.1 - 0.017 15.5 0.1 0.021 15.2 0.1 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EMC91583.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.10 EMC91583.1 - 0.15 12.3 0.5 0.42 10.9 0.5 1.8 1 1 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Svf1_C PF17187.4 EMC91584.1 - 2.8e-55 186.6 0.0 5.9e-55 185.6 0.0 1.5 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EMC91584.1 - 7.4e-53 179.0 0.0 1e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Pkinase PF00069.25 EMC91585.1 - 5.8e-60 202.9 0.9 1.1e-59 202.0 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC91585.1 - 5.2e-35 121.0 0.0 8.6e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EMC91585.1 - 1.9e-29 101.5 16.5 1.8e-15 56.8 4.5 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EMC91585.1 - 2.2e-19 69.1 30.2 2.1e-11 43.5 9.9 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EMC91585.1 - 3.9e-13 49.9 0.7 1.3e-12 48.2 0.7 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 EMC91585.1 - 0.021 14.5 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EMC91585.1 - 0.036 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.6 EMC91585.1 - 0.67 10.1 9.8 0.31 11.2 1.4 2.8 2 1 0 2 2 2 0 Up-regulated During Septation Acetyltransf_7 PF13508.7 EMC91586.1 - 0.00077 19.8 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC91586.1 - 0.00088 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC91586.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC91586.1 - 0.018 15.3 0.0 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 EMC91586.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Kei1 PF08552.11 EMC91588.1 - 9.7e-57 191.9 5.9 1.2e-56 191.6 5.9 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ion_trans PF00520.31 EMC91588.1 - 0.009 15.3 0.1 0.064 12.5 0.0 2.0 2 0 0 2 2 2 1 Ion transport protein Peptidase_M56 PF05569.11 EMC91588.1 - 0.066 12.4 0.1 0.066 12.4 0.1 2.0 2 1 1 3 3 3 0 BlaR1 peptidase M56 CobS PF02654.15 EMC91588.1 - 0.28 11.3 13.3 0.071 13.3 6.3 2.1 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase Ras PF00071.22 EMC91589.1 - 2.8e-57 192.8 0.1 3.6e-57 192.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC91589.1 - 4.3e-36 123.8 0.1 6.4e-36 123.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC91589.1 - 2e-15 56.7 0.1 2.4e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMC91589.1 - 2.2e-05 24.5 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EMC91589.1 - 3.3e-05 23.4 0.1 5.2e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EMC91589.1 - 0.00026 20.9 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EMC91589.1 - 0.0004 19.8 0.1 0.00049 19.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMC91589.1 - 0.00082 19.0 0.0 0.0051 16.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EMC91589.1 - 0.0025 17.3 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B TIR_2 PF13676.6 EMC91589.1 - 0.015 15.9 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 EMC91589.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 EMC91589.1 - 0.21 10.7 0.9 10 5.2 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Nop53 PF07767.11 EMC91590.1 - 9.1e-99 331.5 16.6 1.3e-98 331.0 16.6 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) MatE PF01554.18 EMC91591.1 - 2.4e-59 199.6 25.4 2.6e-36 124.7 9.2 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EMC91591.1 - 5.4e-06 26.5 10.4 5.4e-06 26.5 10.4 3.4 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Nuf2 PF03800.14 EMC91593.1 - 2.8e-42 144.1 0.1 8e-42 142.7 0.1 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EMC91593.1 - 1.6e-29 102.3 19.8 1.6e-29 102.3 19.8 3.6 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain Citrate_bind PF16114.5 EMC91593.1 - 0.17 11.4 0.5 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding DUF4763 PF15960.5 EMC91593.1 - 0.4 9.9 30.0 1.1 8.5 2.6 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) Laminin_II PF06009.12 EMC91593.1 - 3.7 7.6 26.6 0.48 10.4 2.3 3.5 1 1 2 3 3 3 0 Laminin Domain II FUSC PF04632.12 EMC91593.1 - 6.5 5.2 28.5 13 4.2 20.3 2.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family Fez1 PF06818.15 EMC91593.1 - 9.2 6.7 47.4 9.2 6.7 22.8 2.3 1 1 1 2 2 2 0 Fez1 Metallophos PF00149.28 EMC91595.1 - 6.4e-35 121.5 0.2 8.1e-35 121.2 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMC91595.1 - 0.071 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 EMC91595.1 - 0.16 12.4 0.2 0.41 11.1 0.2 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Adaptin_N PF01602.20 EMC91597.1 - 6.9e-93 312.0 0.2 1.1e-92 311.3 0.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EMC91597.1 - 1.7e-14 54.2 3.0 5.4e-12 46.0 0.2 3.7 2 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMC91597.1 - 2e-12 47.3 8.7 6.7e-05 23.2 0.1 5.4 3 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 EMC91597.1 - 1e-09 37.8 6.2 0.0082 16.3 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat Cohesin_HEAT PF12765.7 EMC91597.1 - 0.00018 21.7 4.7 0.25 11.7 0.1 3.1 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 EMC91597.1 - 0.0034 17.5 0.2 2.8 8.1 0.0 3.8 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EMC91597.1 - 0.016 15.7 6.0 17 6.0 0.1 5.2 5 0 0 5 5 5 0 HEAT-like repeat RasGEF_N_2 PF14663.6 EMC91597.1 - 0.02 15.3 0.6 7.3 7.0 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TetR_C_22 PF17928.1 EMC91597.1 - 0.078 13.3 0.5 12 6.2 0.0 3.7 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_125 PF06824.11 EMC91598.1 - 5.9e-180 598.6 0.0 7e-180 598.3 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) RRM_1 PF00076.22 EMC91600.1 - 3.8e-24 84.3 5.1 9.3e-12 44.6 0.4 3.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMC91600.1 - 0.0018 17.8 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 EMC91600.1 - 0.013 15.2 0.2 0.033 13.9 0.0 1.7 1 1 0 1 1 1 0 Calcipressin MFS_1 PF07690.16 EMC91601.1 - 1.5e-44 152.4 12.9 2.8e-41 141.6 10.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMC91601.1 - 0.00037 19.9 13.5 0.0023 17.3 5.8 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EMC91601.1 - 0.00059 18.3 0.0 0.0047 15.3 0.0 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EMC91601.1 - 0.0008 18.4 6.3 1.9 7.3 3.7 3.3 2 1 1 3 3 3 3 MFS_1 like family SNF2_N PF00176.23 EMC91603.1 - 9.3e-55 185.7 0.1 3.2e-54 184.0 0.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EMC91603.1 - 3e-11 43.6 0.0 6.9e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMC91603.1 - 1.2e-09 38.5 0.0 3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EMC91603.1 - 1.7e-05 24.7 6.3 3.1e-05 23.8 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EMC91603.1 - 0.001 18.9 4.9 0.0017 18.2 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC91603.1 - 0.0015 18.3 6.9 0.0042 16.9 6.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SWI2_SNF2 PF18766.1 EMC91603.1 - 0.0017 18.0 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-RING_UBOX PF13445.6 EMC91603.1 - 0.002 18.1 3.2 0.0042 17.1 3.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EMC91603.1 - 0.054 13.4 2.9 0.11 12.3 2.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EMC91603.1 - 0.22 11.4 3.7 0.56 10.1 3.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMC91603.1 - 4.3 7.6 6.5 11 6.3 6.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PKD_channel PF08016.12 EMC91604.1 - 0.0058 15.4 20.1 0.21 10.2 20.1 2.2 1 1 0 1 1 1 1 Polycystin cation channel Synaptobrevin PF00957.21 EMC91605.1 - 4.5e-31 106.5 0.0 6.1e-31 106.1 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EMC91605.1 - 9.3e-28 96.1 0.0 1.4e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF5542 PF17696.1 EMC91605.1 - 0.026 14.6 0.5 0.047 13.8 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5542) SRP-alpha_N PF04086.13 EMC91605.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Tautomerase_3 PF14832.6 EMC91606.1 - 4.5e-12 46.4 0.0 8.2e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme TMA7 PF09072.10 EMC91606.1 - 0.14 13.0 0.4 0.42 11.5 0.3 1.9 1 1 0 1 1 1 0 Translation machinery associated TMA7 eIF-1a PF01176.19 EMC91607.1 - 5.8e-15 54.9 0.0 8.1e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 EMC91608.1 - 9.1e-148 492.5 12.0 1.1e-147 492.2 12.0 1.0 1 0 0 1 1 1 1 ALG3 protein adh_short PF00106.25 EMC91609.1 - 4.3e-30 104.6 0.0 8.9e-23 80.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC91609.1 - 2.9e-19 69.6 0.0 8e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC91609.1 - 4.1e-12 46.4 0.4 2.8e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 EMC91609.1 - 0.004 16.4 0.0 0.011 14.9 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EMC91609.1 - 0.0082 15.3 0.0 0.035 13.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMC91609.1 - 0.018 14.9 0.1 0.25 11.2 0.1 2.3 2 1 0 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 EMC91609.1 - 0.022 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 EMC91609.1 - 0.022 14.2 0.0 0.055 12.9 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family IF-2B PF01008.17 EMC91610.1 - 3.3e-50 170.9 0.0 4.2e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 EMC91610.1 - 0.027 14.4 0.2 3 7.8 0.0 2.6 3 0 0 3 3 3 0 DeoR C terminal sensor domain Cpn60_TCP1 PF00118.24 EMC91611.1 - 7.3e-150 499.8 12.5 8.3e-150 499.6 12.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 EMC91611.1 - 0.053 13.0 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Telomere recombination ATP-synt_Eps PF04627.13 EMC91611.1 - 1.1 9.3 2.9 1.3 9.0 0.3 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Dcc1 PF09724.9 EMC91612.1 - 1.2e-30 107.0 0.0 1.5e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Hemerythrin PF01814.23 EMC91613.1 - 4.7e-11 43.4 3.5 6.7e-11 42.9 3.5 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain SH3_9 PF14604.6 EMC91614.1 - 7.9e-06 25.6 0.1 1.8e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMC91614.1 - 1.2e-05 24.8 0.3 2.4e-05 23.9 0.3 1.4 1 0 0 1 1 1 1 SH3 domain DUF4690 PF15756.5 EMC91614.1 - 1.9 9.1 7.2 0.27 11.9 2.4 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF4674 PF15719.5 EMC91615.1 - 0.006 16.6 0.3 0.0066 16.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4674) PPR_3 PF13812.6 EMC91616.1 - 0.0011 19.0 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EMC91616.1 - 0.014 15.6 0.0 0.054 13.7 0.0 2.1 3 0 0 3 3 3 0 PPR repeat family PPR_1 PF12854.7 EMC91616.1 - 1 9.1 2.4 0.72 9.6 0.2 1.9 2 0 0 2 2 2 0 PPR repeat TetR_C_6 PF13977.6 EMC91616.1 - 1.6 9.0 6.5 3 8.1 0.7 3.1 3 0 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal Pkinase PF00069.25 EMC91617.1 - 1.7e-30 106.3 0.0 1.9e-18 66.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMC91617.1 - 1.6e-13 50.6 0.0 2e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMC91617.1 - 0.02 13.7 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase RabGAP-TBC PF00566.18 EMC91618.1 - 1.3e-36 126.2 0.0 1.7e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FAD_binding_3 PF01494.19 EMC91619.1 - 7.7e-72 242.4 0.0 9.6e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMC91619.1 - 6.6e-35 120.6 0.0 1.3e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EMC91619.1 - 0.0011 18.3 0.2 0.057 12.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC91619.1 - 0.0069 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC91619.1 - 0.023 14.3 0.4 0.47 10.0 0.1 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 EMC91619.1 - 0.027 14.0 0.1 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EMC91619.1 - 0.034 14.7 0.0 0.16 12.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_43 PF04616.14 EMC91620.1 - 7.8e-23 81.2 0.5 1.1e-22 80.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Radical_SAM PF04055.21 EMC91621.1 - 3.3e-10 40.6 0.0 1.3e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EMC91621.1 - 0.00021 21.6 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMC91621.1 - 0.071 13.3 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain MAGI_u1 PF16663.5 EMC91621.1 - 0.12 12.5 0.2 4.8 7.3 0.0 2.7 3 0 0 3 3 3 0 Unstructured region on MAGI DUF1054 PF06335.12 EMC91621.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) tRNA_int_endo PF01974.17 EMC91622.1 - 4.3e-15 55.6 0.0 9.1e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Toprim_2 PF13155.6 EMC91622.1 - 0.048 14.1 0.3 0.092 13.2 0.3 1.5 1 0 0 1 1 1 0 Toprim-like Sugar_tr PF00083.24 EMC91624.1 - 2e-92 310.5 23.4 2.5e-92 310.1 23.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC91624.1 - 1.4e-12 47.3 47.5 5.6e-09 35.4 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 EMC91626.1 - 1.1e-35 123.0 0.0 1.9e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC91626.1 - 5.1e-20 71.9 0.0 1.5e-18 67.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC91626.1 - 0.0013 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EMC91626.1 - 0.095 13.0 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Anp1 PF03452.14 EMC91627.1 - 1.2e-110 369.0 0.0 1.9e-110 368.4 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glyco_tranf_2_4 PF13704.6 EMC91627.1 - 0.017 15.6 0.1 0.056 14.0 0.1 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF3040 PF11239.8 EMC91627.1 - 0.059 13.6 0.5 1.8 8.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Rad54_N PF08658.10 EMC91627.1 - 0.67 10.1 3.2 1.4 9.1 3.2 1.5 1 1 0 1 1 1 0 Rad54 N terminal CR6_interact PF10147.9 EMC91627.1 - 2.3 7.9 13.5 4.2 7.0 13.5 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF5401 PF17380.2 EMC91627.1 - 4.2 5.3 20.3 6.1 4.8 20.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) CLTH PF10607.9 EMC91629.1 - 1.9e-31 109.0 0.0 2.4e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EMC91629.1 - 8.8e-08 31.8 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 LisH baeRF_family12 PF18856.1 EMC91629.1 - 0.059 14.0 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 PRK PF00485.18 EMC91630.1 - 1.2e-58 198.1 0.0 1.6e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EMC91630.1 - 7.2e-35 120.3 0.0 1.2e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CPT PF07931.12 EMC91630.1 - 1.1e-05 25.4 0.0 2.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 EMC91630.1 - 6.4e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EMC91630.1 - 0.00073 20.1 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMC91630.1 - 0.0041 17.3 0.0 0.05 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EMC91630.1 - 0.016 15.7 0.1 0.038 14.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 EMC91630.1 - 0.03 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.29 EMC91630.1 - 0.034 14.6 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EMC91630.1 - 0.035 14.5 0.2 0.37 11.2 0.2 2.3 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 EMC91630.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IBR PF01485.21 EMC91631.1 - 8.5e-17 61.1 20.6 5.9e-11 42.4 5.3 3.9 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Paramyxo_NS_C PF02725.14 EMC91631.1 - 0.061 13.4 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Non-structural protein C PhnA_Zn_Ribbon PF08274.12 EMC91631.1 - 0.55 10.2 0.1 0.55 10.2 0.1 5.0 5 0 0 5 5 5 0 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.6 EMC91631.1 - 0.65 9.8 0.1 0.65 9.8 0.1 4.6 5 1 1 6 6 6 0 zinc-ribbon domain Elf1 PF05129.13 EMC91631.1 - 0.82 9.8 21.8 2.9 8.0 0.7 3.5 3 1 0 3 3 3 0 Transcription elongation factor Elf1 like DUF4385 PF14328.6 EMC91632.1 - 6.7e-54 181.9 0.3 8.9e-54 181.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) DUF3350 PF11830.8 EMC91632.1 - 0.0095 16.2 0.8 0.018 15.4 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3350) MFS_1 PF07690.16 EMC91633.1 - 1.5e-08 34.0 37.6 4.6e-07 29.1 11.6 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily Radical_SAM PF04055.21 EMC91634.1 - 1.8e-22 80.5 0.0 9.5e-22 78.1 0.0 2.1 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 EMC91634.1 - 2e-22 79.3 0.0 4.5e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 EMC91634.1 - 1.9e-11 44.3 0.0 4.6e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EMC91634.1 - 0.087 13.1 0.1 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin domain IBR PF01485.21 EMC91635.1 - 0.6 10.4 30.8 0.044 14.0 9.1 3.4 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain TFCD_C PF12612.8 EMC91636.1 - 1.7e-16 60.6 0.8 6.5e-14 52.2 0.5 3.7 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal PUL PF08324.11 EMC91636.1 - 0.0022 17.3 1.0 0.013 14.8 0.1 2.7 2 1 1 3 3 3 1 PUL domain Vac14_Fab1_bd PF12755.7 EMC91636.1 - 0.023 15.3 0.1 0.39 11.3 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EMC91636.1 - 0.024 14.7 0.0 0.7 9.9 0.0 3.4 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EMC91636.1 - 0.055 13.7 14.1 0.63 10.5 0.1 6.4 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 EMC91636.1 - 0.25 11.7 17.1 3.2 8.2 0.1 5.7 6 0 0 6 6 6 0 HEAT repeats DUF2267 PF10025.9 EMC91636.1 - 0.39 11.0 5.6 0.12 12.7 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) CDC27 PF09507.10 EMC91637.1 - 6.9e-81 272.8 30.8 3.5e-80 270.5 30.8 1.8 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Ribosomal_S25 PF03297.15 EMC91637.1 - 2.5 8.4 6.5 4.6 7.5 0.0 3.0 3 0 0 3 3 3 0 S25 ribosomal protein MOR2-PAG1_N PF14222.6 EMC91638.1 - 3e-191 637.1 0.0 4.9e-191 636.4 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EMC91638.1 - 2.2e-90 302.9 0.0 5.7e-90 301.6 0.0 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EMC91638.1 - 5.4e-31 107.2 2.0 2.9e-14 51.8 0.1 3.2 1 1 2 3 3 3 3 Cell morphogenesis central region HEAT PF02985.22 EMC91638.1 - 0.07 13.4 0.4 18 5.9 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat TRF PF08558.10 EMC91642.1 - 5.3e-53 180.1 0.0 6.8e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EMC91642.1 - 0.0013 18.8 0.1 0.0028 17.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.14 EMC91642.1 - 0.014 16.1 0.0 0.12 13.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.6 EMC91642.1 - 0.12 12.7 0.1 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4272 PF14094.6 EMC91643.1 - 0.096 11.9 0.6 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4272) Pex2_Pex12 PF04757.14 EMC91644.1 - 9.4e-51 172.6 3.8 1.2e-50 172.2 3.8 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EMC91644.1 - 0.0012 18.7 0.3 0.0017 18.1 0.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC91644.1 - 0.0015 18.4 0.7 0.0024 17.6 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMC91644.1 - 0.0041 17.3 0.5 0.0067 16.6 0.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EMC91644.1 - 0.0042 16.9 0.3 0.0068 16.3 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC91644.1 - 0.0043 17.4 0.4 0.0069 16.7 0.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EMC91644.1 - 0.014 15.4 0.3 0.026 14.6 0.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-piccolo PF05715.13 EMC91644.1 - 0.27 11.4 0.7 0.46 10.7 0.7 1.3 1 0 0 1 1 1 0 Piccolo Zn-finger DASH_Dad1 PF08649.10 EMC91645.1 - 2.6e-25 88.4 1.9 3e-25 88.1 1.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EMC91645.1 - 0.07 13.1 0.4 0.092 12.7 0.4 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 ATP_bind_3 PF01171.20 EMC91646.1 - 1.6e-39 135.6 0.0 2.1e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family VWA PF00092.28 EMC91646.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 2 0 0 2 2 2 0 von Willebrand factor type A domain zf-B_box PF00643.24 EMC91647.1 - 4.7 7.4 13.9 0.27 11.4 6.5 2.7 3 0 0 3 3 3 0 B-box zinc finger Pkinase PF00069.25 EMC91648.1 - 1.2e-47 162.5 0.0 2.6e-47 161.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC91648.1 - 1.6e-20 73.5 0.0 3.1e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMC91648.1 - 0.013 15.5 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMC91648.1 - 0.014 14.3 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain EURL PF06937.11 EMC91648.1 - 0.077 12.4 0.6 0.14 11.5 0.6 1.3 1 0 0 1 1 1 0 EURL protein Kinase-like PF14531.6 EMC91648.1 - 0.11 11.8 0.2 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Acetyltransf_1 PF00583.25 EMC91649.1 - 1.4e-10 41.4 0.1 2.3e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC91649.1 - 0.00017 21.6 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC91649.1 - 0.00067 19.7 0.3 0.0016 18.6 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC91649.1 - 0.0011 19.3 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EMC91649.1 - 0.0015 18.2 0.1 0.0032 17.2 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EMC91649.1 - 0.0028 17.8 0.2 0.009 16.1 0.1 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Pho86 PF11124.8 EMC91649.1 - 0.034 13.6 0.6 1.6 8.1 0.1 2.1 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 DUF1768 PF08719.11 EMC91650.1 - 8.9e-22 78.0 0.2 1.1e-21 77.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) MFS_1 PF07690.16 EMC91651.1 - 2.9e-25 89.0 63.6 1.4e-18 66.9 30.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMC91651.1 - 2.1e-06 27.3 34.2 2.8e-06 26.9 34.2 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Tfb4 PF03850.14 EMC91652.1 - 7.7e-99 330.6 0.0 9.2e-99 330.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF4796 PF16044.5 EMC91652.1 - 0.09 12.4 0.5 0.16 11.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Glyco_hydro_35 PF01301.19 EMC91653.1 - 5.6e-89 298.9 0.0 8.8e-89 298.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EMC91653.1 - 1.9e-63 213.6 2.3 1.9e-63 213.6 1.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EMC91653.1 - 3.4e-56 188.7 8.8 4.3e-31 107.9 0.3 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EMC91653.1 - 2.9e-20 71.6 0.2 8.5e-20 70.1 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Asparaginase_2 PF01112.18 EMC91654.1 - 7.7e-44 149.9 3.2 1.5e-29 103.0 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.19 EMC91655.1 - 6.5e-88 295.1 0.0 2.2e-85 286.7 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EMC91655.1 - 0.0084 15.0 0.0 0.47 9.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Fungal_trans PF04082.18 EMC91656.1 - 8e-18 64.4 0.0 1.5e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC91656.1 - 1.5e-05 25.0 6.9 3e-05 24.0 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRMT5 PF05185.16 EMC91657.1 - 3.7e-66 222.2 0.0 5.9e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 EMC91657.1 - 5.6e-65 219.1 0.0 8e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 EMC91657.1 - 5.4e-56 189.2 0.0 8.9e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain DUF4999 PF16390.5 EMC91657.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function G-patch PF01585.23 EMC91658.1 - 9.8e-08 31.8 0.1 1.8e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EMC91658.1 - 0.058 13.5 0.5 0.12 12.5 0.5 1.5 1 0 0 1 1 1 0 G-patch domain SNARE PF05739.19 EMC91659.1 - 4e-09 36.3 0.6 7.6e-09 35.4 0.6 1.5 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EMC91659.1 - 1.3e-05 25.0 5.9 3.5e-05 23.6 5.9 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 XhlA PF10779.9 EMC91659.1 - 0.0035 17.5 1.7 0.0086 16.3 0.1 2.3 2 0 0 2 2 2 1 Haemolysin XhlA Sec20 PF03908.13 EMC91659.1 - 0.011 15.7 1.0 0.16 11.9 0.1 2.6 2 1 1 3 3 3 0 Sec20 Fusion_gly PF00523.18 EMC91659.1 - 0.075 11.3 0.2 0.1 10.8 0.2 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 CorA PF01544.18 EMC91659.1 - 0.09 12.1 0.3 0.09 12.1 0.3 3.0 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein EMP24_GP25L PF01105.24 EMC91659.1 - 0.18 11.8 5.3 0.21 11.5 1.1 2.4 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FAM167 PF11652.8 EMC91659.1 - 2.5 8.6 5.7 2.9 8.5 0.9 3.0 2 1 1 3 3 3 0 FAM167 Spc24 PF08286.11 EMC91659.1 - 3.4 7.9 6.2 13 6.0 0.3 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Myb_Cef PF11831.8 EMC91660.1 - 2.9e-47 161.2 1.8 2.9e-47 161.2 1.8 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EMC91660.1 - 1.7e-20 72.9 3.2 2.5e-09 37.2 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC91660.1 - 4e-19 68.6 3.2 3.7e-12 46.3 0.9 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain IBN_N PF03810.19 EMC91662.1 - 2.4e-09 37.0 0.1 9.4e-09 35.1 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EMC91662.1 - 7.1e-06 26.1 0.0 0.0021 18.1 0.0 2.9 2 0 0 2 2 2 2 Exportin 1-like protein CAS_CSE1 PF03378.15 EMC91662.1 - 0.11 11.0 0.0 0.21 10.0 0.0 1.4 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus RIX1 PF08167.12 EMC91662.1 - 0.11 12.2 0.2 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EMC91662.1 - 1.6 9.4 6.3 5.1 7.7 0.5 4.6 4 0 0 4 4 4 0 HEAT-like repeat HORMA PF02301.18 EMC91664.1 - 2.4e-12 46.9 0.0 3.1e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 HORMA domain MatP PF06303.12 EMC91665.1 - 0.093 13.3 1.7 0.32 11.6 0.1 2.6 3 0 0 3 3 3 0 MatP N-terminal domain F-box-like PF12937.7 EMC91665.1 - 0.096 12.6 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 F-box-like Amidohydro_1 PF01979.20 EMC91666.1 - 3.7e-40 138.3 0.0 4.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMC91666.1 - 4e-14 53.0 0.3 6.8e-11 42.3 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Acyltransferase PF01553.21 EMC91667.1 - 1.3e-15 57.2 0.0 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase PAXNEB PF05625.11 EMC91669.1 - 2.7e-102 342.7 0.0 3.1e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein DUF775 PF05603.12 EMC91670.1 - 1.7e-66 223.6 0.0 1.9e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF4743 PF15916.5 EMC91671.1 - 2.1e-13 50.3 0.0 3.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EMC91671.1 - 4.1e-10 39.8 0.3 8.2e-10 38.8 0.3 1.5 1 0 0 1 1 1 1 NUDIX domain TRI5 PF06330.11 EMC91673.1 - 9.1e-149 495.2 2.4 1.1e-148 495.0 2.4 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.22 EMC91674.1 - 4.7e-52 177.3 0.0 6.1e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Herpes_BMRF2 PF04633.12 EMC91674.1 - 0.076 12.2 0.4 3.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus BMRF2 protein Npa1 PF11707.8 EMC91675.1 - 1.5e-89 300.7 0.4 3.4e-88 296.3 0.1 2.2 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EMC91675.1 - 9e-57 191.9 0.3 2.4e-56 190.5 0.3 1.8 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 HEAT_2 PF13646.6 EMC91675.1 - 2.2 8.7 5.2 13 6.3 0.2 3.6 3 0 0 3 3 3 0 HEAT repeats Met_10 PF02475.16 EMC91677.1 - 0.0018 18.1 0.0 0.0045 16.8 0.0 1.7 1 1 0 1 1 1 1 Met-10+ like-protein EF-hand_6 PF13405.6 EMC91678.1 - 3.3e-05 23.5 0.5 0.064 13.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EMC91678.1 - 0.00023 21.6 0.3 0.00057 20.3 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EMC91678.1 - 0.00096 18.5 0.1 0.0029 17.1 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EMC91678.1 - 0.043 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair IML1 PF12257.8 EMC91679.1 - 4e-79 265.7 1.3 2.7e-78 263.0 1.3 2.0 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EMC91679.1 - 1.3e-21 76.4 0.2 2.8e-21 75.3 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF72 PF01904.18 EMC91679.1 - 0.036 14.2 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF72 GST_N_2 PF13409.6 EMC91680.1 - 5.3e-21 74.7 0.0 1.4e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMC91680.1 - 2.2e-14 53.2 0.0 5.5e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC91680.1 - 5.1e-08 33.0 0.1 2.1e-07 31.0 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMC91680.1 - 3.9e-06 27.2 0.1 8.4e-05 22.9 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMC91680.1 - 0.00012 22.2 0.6 0.00063 19.9 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMC91680.1 - 0.0034 17.9 0.0 0.006 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 EMC91681.1 - 0.00015 21.5 0.0 0.0041 16.9 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF604 PF04646.12 EMC91682.1 - 9.2e-10 38.3 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EMC91682.1 - 2.9e-07 30.2 0.0 5.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_90 PF05686.12 EMC91683.1 - 1.4e-23 83.5 2.0 1.9e-23 83.1 2.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 BCL9 PF11502.8 EMC91683.1 - 0.1 12.4 2.0 0.63 9.9 0.1 2.5 2 0 0 2 2 2 0 B-cell lymphoma 9 protein HAD PF12710.7 EMC91684.1 - 5e-25 89.0 0.0 7.5e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EMC91684.1 - 0.00077 18.9 0.0 0.0067 15.9 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 EMC91684.1 - 0.032 13.8 0.1 0.16 11.4 0.0 2.1 2 1 1 3 3 3 0 Pyrimidine 5'-nucleotidase (UMPH-1) P3A PF08727.11 EMC91684.1 - 0.15 11.5 0.0 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Poliovirus 3A protein like She9_MDM33 PF05546.11 EMC91685.1 - 3.5e-54 183.6 3.1 5.9e-54 182.9 3.1 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family CpXC PF14353.6 EMC91685.1 - 0.016 15.2 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 CpXC protein Sec8_exocyst PF04048.14 EMC91685.1 - 0.26 11.2 4.5 4.2 7.3 0.4 3.1 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain IATP PF04568.12 EMC91685.1 - 0.28 11.6 2.4 20 5.7 1.3 2.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF1681 PF07933.14 EMC91686.1 - 7.8e-53 178.2 0.0 1e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Ribosom_S12_S23 PF00164.25 EMC91687.1 - 9.9e-32 108.9 0.8 1.3e-31 108.5 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 EMC91687.1 - 0.062 14.0 0.0 0.16 12.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S12 RNase_T PF00929.24 EMC91689.1 - 1e-11 45.6 0.0 1.9e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EMC91689.1 - 0.0071 16.1 0.0 0.039 13.7 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease ANAPC15 PF15243.6 EMC91689.1 - 7.7 7.0 10.1 25 5.3 4.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 MOZ_SAS PF01853.18 EMC91690.1 - 1.4e-80 269.2 0.0 2e-80 268.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EMC91690.1 - 2e-24 84.9 1.8 4e-24 84.0 1.8 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EMC91690.1 - 3.1e-23 81.4 0.1 6.2e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EMC91690.1 - 0.00036 20.9 0.0 0.0008 19.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC91690.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Chromo PF00385.24 EMC91690.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-U1 PF06220.12 EMC91690.1 - 0.28 11.0 3.1 0.69 9.7 3.1 1.6 1 0 0 1 1 1 0 U1 zinc finger HAND PF09110.11 EMC91690.1 - 0.43 11.3 6.9 0.17 12.6 2.7 2.3 2 0 0 2 2 2 0 HAND IBR PF01485.21 EMC91691.1 - 7.5e-16 58.1 22.7 2.4e-09 37.3 3.2 3.3 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DpnI PF06044.12 EMC91691.1 - 0.0034 17.0 7.3 0.12 12.0 0.1 2.2 2 0 0 2 2 2 2 Dam-replacing family DEAD PF00270.29 EMC91692.1 - 2.4e-49 167.5 0.0 5.7e-49 166.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC91692.1 - 1.2e-22 80.3 0.0 1.4e-21 76.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EMC91692.1 - 2.5e-21 75.7 5.3 2.5e-21 75.7 5.3 2.4 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 EMC91692.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RPA_C PF08784.11 EMC91693.1 - 1.1e-16 61.4 0.9 2.2e-16 60.4 0.9 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EMC91693.1 - 7.1e-06 25.9 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain BOF PF04076.13 EMC91693.1 - 0.015 15.4 0.1 0.05 13.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial OB fold (BOF) protein CDC24_OB3 PF17244.2 EMC91693.1 - 0.16 11.6 0.1 0.26 11.0 0.1 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 adh_short PF00106.25 EMC91694.1 - 4.3e-25 88.3 0.0 5.3e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC91694.1 - 1.9e-20 73.5 0.0 2.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC91694.1 - 2.7e-08 33.9 0.1 4.9e-08 33.1 0.1 1.4 1 1 0 1 1 1 1 KR domain DUF460 PF04312.13 EMC91694.1 - 0.045 13.5 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) NAD_binding_10 PF13460.6 EMC91694.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF866 PF05907.13 EMC91696.1 - 2e-66 222.7 1.1 2.3e-66 222.5 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Rubredoxin_2 PF18073.1 EMC91696.1 - 0.52 10.1 5.4 2.5 7.9 0.4 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF4379 PF14311.6 EMC91696.1 - 0.8 10.1 5.6 0.29 11.5 1.7 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain zf-DNL PF05180.12 EMC91696.1 - 4.1 7.4 5.6 67 3.5 0.1 3.0 2 1 0 2 2 2 0 DNL zinc finger Zn_ribbon_SprT PF17283.2 EMC91696.1 - 5.4 7.0 7.7 64 3.6 7.7 2.2 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Pyr_redox_2 PF07992.14 EMC91698.1 - 5.2e-39 134.2 0.0 7.4e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC91698.1 - 5.4e-11 42.9 0.0 4.6e-08 33.5 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EMC91698.1 - 4.1e-06 26.0 0.1 1.2e-05 24.5 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EMC91698.1 - 1.7e-05 24.4 0.3 6.8e-05 22.5 0.3 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EMC91698.1 - 9.9e-05 22.7 0.1 0.00033 21.1 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EMC91698.1 - 0.0002 20.7 0.4 0.00048 19.5 0.4 1.7 1 0 0 1 1 1 1 EF hand DNA_pol3_tau_5 PF12170.8 EMC91698.1 - 0.14 12.2 0.4 0.33 11.0 0.4 1.6 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha Aldedh PF00171.22 EMC91699.1 - 7.1e-122 407.2 0.0 8e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMC91699.1 - 4.7e-06 25.9 0.0 8.7e-06 25.0 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pinin_SDK_N PF04697.13 EMC91700.1 - 0.65 10.6 3.4 5.7 7.6 0.4 2.6 3 0 0 3 3 3 0 pinin/SDK conserved region LRR_9 PF14580.6 EMC91702.1 - 2.5e-60 203.0 0.0 3.7e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EMC91702.1 - 1.7e-07 31.4 9.3 7.9e-07 29.3 2.0 3.7 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMC91702.1 - 5.6e-06 26.0 1.1 5.6e-06 26.0 1.1 2.4 2 0 0 2 2 2 1 Leucine rich repeat Gp-FAR-1 PF05823.12 EMC91702.1 - 0.016 15.6 0.6 0.028 14.8 0.6 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DIM1 PF02966.16 EMC91703.1 - 4.8e-69 230.3 0.6 5.4e-69 230.1 0.6 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EMC91703.1 - 0.0002 21.3 0.0 0.00026 20.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EMC91703.1 - 0.011 16.0 1.0 0.024 14.9 1.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Clr2_transil PF16761.5 EMC91704.1 - 1e-24 87.1 0.1 1.9e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EMC91704.1 - 2.1e-10 41.6 1.4 2.4e-09 38.1 0.0 2.7 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 SNF2_N PF00176.23 EMC91705.1 - 1.6e-55 188.2 0.1 2.5e-55 187.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC91705.1 - 1e-14 54.8 0.1 2.1e-12 47.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC91705.1 - 1.3e-07 31.7 0.0 3.7e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EMC91705.1 - 5e-06 25.9 0.0 8.7e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 EMC91705.1 - 0.00016 21.5 8.8 0.00016 21.5 8.8 2.8 2 1 1 3 3 3 1 PHD-finger Zf_RING PF16744.5 EMC91705.1 - 3.7 7.7 17.0 12 6.1 1.9 3.4 3 0 0 3 3 3 0 KIAA1045 RING finger MoCF_biosynth PF00994.24 EMC91708.1 - 8.1e-34 116.3 0.0 1.5e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 EMC91708.1 - 0.062 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain FAD_syn PF06574.12 EMC91708.1 - 0.081 12.8 0.0 6 6.7 0.0 2.2 2 0 0 2 2 2 0 FAD synthetase RSN1_7TM PF02714.15 EMC91709.1 - 5.6e-89 298.1 18.6 5.6e-89 298.1 18.6 2.4 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMC91709.1 - 1.7e-37 128.6 1.9 1.7e-37 128.6 1.9 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMC91709.1 - 3.5e-35 121.8 0.0 6.3e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EMC91709.1 - 3.3e-30 104.1 0.1 6.3e-30 103.2 0.1 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF3377 PF11857.8 EMC91709.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3377) NHS PF15273.6 EMC91711.1 - 0.027 13.6 1.0 0.033 13.3 1.0 1.1 1 0 0 1 1 1 0 NHS-like GATase PF00117.28 EMC91712.1 - 4e-42 144.1 0.0 8.3e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 EMC91712.1 - 5.8e-32 109.6 0.0 1.5e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 EMC91712.1 - 6.3e-10 38.6 0.0 1.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EMC91712.1 - 8.2e-08 32.3 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 EMC91712.1 - 0.0001 21.9 0.1 0.0008 19.0 0.1 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 EMC91712.1 - 0.00016 21.4 0.0 0.00094 18.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 EMC91712.1 - 0.00022 20.1 0.3 0.00086 18.2 0.1 1.9 2 0 0 2 2 2 1 tRNA methyl transferase Arginosuc_synth PF00764.19 EMC91712.1 - 0.00092 18.6 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.20 EMC91712.1 - 0.013 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.19 EMC91712.1 - 0.032 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiF PF00899.21 EMC91714.1 - 6e-13 48.7 0.0 1.6e-12 47.3 0.0 1.7 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 EMC91714.1 - 0.0014 18.7 0.3 2.5 8.3 0.0 3.7 4 0 0 4 4 4 2 Ubiquitin-activating enzyme E1 four-helix bundle PAG PF15347.6 EMC91714.1 - 0.073 12.1 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched DUF2277 PF10041.9 EMC91714.1 - 0.091 13.1 0.0 0.78 10.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) Rib_5-P_isom_A PF06026.14 EMC91715.1 - 6.1e-43 146.4 0.0 8.4e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) GATA PF00320.27 EMC91716.1 - 6.2e-33 112.1 16.9 5.5e-17 61.1 4.7 2.1 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 EMC91716.1 - 9.4e-07 28.8 1.4 0.0041 17.2 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 EMC91716.1 - 1.3e-06 27.8 5.7 0.0038 16.7 0.6 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.7 EMC91716.1 - 2.4e-06 27.5 3.0 1.8e-05 24.6 3.1 2.2 1 1 0 1 1 1 1 Double zinc ribbon eIF-5_eIF-2B PF01873.17 EMC91716.1 - 9.4e-05 22.3 3.6 0.065 13.1 0.2 2.4 2 0 0 2 2 2 2 Domain found in IF2B/IF5 ArfGap PF01412.18 EMC91716.1 - 0.00014 21.9 2.3 0.046 13.8 0.0 2.1 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf TDP43_N PF18694.1 EMC91716.1 - 0.00068 19.4 0.2 0.099 12.5 0.0 2.1 2 0 0 2 2 2 1 Transactive response DNA-binding protein N-terminal domain OrfB_Zn_ribbon PF07282.11 EMC91716.1 - 0.00098 19.0 5.3 0.11 12.4 0.7 2.2 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 EMC91716.1 - 0.0011 19.0 6.0 0.21 11.8 0.7 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RRPl_C4 PF17026.5 EMC91716.1 - 0.002 18.2 1.9 0.024 14.7 2.4 2.0 1 1 1 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type zf-Sec23_Sec24 PF04810.15 EMC91716.1 - 0.0022 18.0 5.4 0.016 15.3 0.2 2.5 2 1 0 2 2 2 1 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 EMC91716.1 - 0.007 15.7 9.7 6 6.4 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_L32p PF01783.23 EMC91716.1 - 0.015 15.5 11.6 0.65 10.3 2.1 4.1 2 2 0 2 2 2 0 Ribosomal L32p protein family HypA PF01155.19 EMC91716.1 - 0.017 15.1 3.4 0.16 12.0 1.4 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 EMC91716.1 - 0.02 15.7 4.5 0.047 14.5 1.9 2.5 1 1 2 3 3 3 0 zinc-ribbon family DUF2387 PF09526.10 EMC91716.1 - 0.03 14.5 0.2 1.2 9.4 0.1 2.1 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Rubredoxin_2 PF18073.1 EMC91716.1 - 0.033 13.9 9.7 8.3 6.2 0.1 4.2 4 0 0 4 4 4 0 Rubredoxin metal binding domain zf-CHY PF05495.12 EMC91716.1 - 0.033 14.7 1.3 0.19 12.2 0.5 2.2 1 1 1 2 2 2 0 CHY zinc finger zinc_ribbon_2 PF13240.6 EMC91716.1 - 0.077 12.7 12.7 0.74 9.6 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.13 EMC91716.1 - 0.1 12.7 5.4 3.2 7.9 0.1 3.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 EMC91716.1 - 0.32 11.4 6.2 5.7 7.4 2.7 3.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar Prim_Zn_Ribbon PF08273.12 EMC91716.1 - 0.39 11.0 11.2 5.4 7.4 2.8 3.2 2 2 0 2 2 2 0 Zinc-binding domain of primase-helicase DNA_RNApol_7kD PF03604.13 EMC91716.1 - 0.51 10.1 9.3 5.1 6.9 0.0 3.7 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit FYVE PF01363.21 EMC91716.1 - 1.2 9.4 5.2 6.1 7.1 0.8 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_3 PF13878.6 EMC91716.1 - 1.2 9.0 10.3 6.3 6.7 0.0 3.7 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-RING_7 PF02591.15 EMC91716.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.4 4 0 0 4 4 4 0 C4-type zinc ribbon domain Nudix_N_2 PF14803.6 EMC91716.1 - 4.5 7.3 14.8 2.8 8.0 1.4 3.9 4 1 0 4 4 3 0 Nudix N-terminal zf-RING_5 PF14634.6 EMC91716.1 - 5.1 7.1 10.6 36 4.4 0.3 3.5 2 2 0 2 2 2 0 zinc-RING finger domain zf-RRN7 PF11781.8 EMC91716.1 - 7.8 6.3 13.6 2.8 7.7 3.3 3.5 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Tnp_zf-ribbon_2 PF13842.6 EMC91716.1 - 7.9 7.4 10.1 18 6.2 0.7 3.5 2 2 1 3 3 3 0 DDE_Tnp_1-like zinc-ribbon Ribosomal_S27e PF01667.17 EMC91716.1 - 9.2 6.1 8.6 3.6 7.4 0.4 2.9 3 1 0 3 3 3 0 Ribosomal protein S27 Zn_ribbon_recom PF13408.6 EMC91716.1 - 9.8 6.8 11.5 15 6.2 2.1 2.9 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain COPI_assoc PF08507.10 EMC91717.1 - 1.9e-31 108.8 5.7 2.3e-31 108.6 5.7 1.0 1 0 0 1 1 1 1 COPI associated protein DUF3681 PF12442.8 EMC91717.1 - 0.095 13.2 4.3 0.067 13.7 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) CBP_BcsF PF11120.8 EMC91717.1 - 0.3 11.2 0.2 0.3 11.2 0.2 2.4 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF DUF202 PF02656.15 EMC91717.1 - 0.7 10.4 11.7 0.82 10.2 6.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3096 PF11295.8 EMC91717.1 - 3 7.6 12.0 1.8 8.3 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) FUSC-like PF12805.7 EMC91717.1 - 5.3 6.0 4.7 2.4 7.2 2.6 1.4 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS DAO PF01266.24 EMC91718.1 - 1e-36 127.2 3.0 1.2e-36 127.0 3.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC91718.1 - 2.4e-05 24.5 0.1 6e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMC91718.1 - 8.3e-05 21.9 1.2 0.00011 21.5 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EMC91718.1 - 0.00027 20.2 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC91718.1 - 0.0012 18.1 1.5 0.0015 17.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC91718.1 - 0.0023 16.9 0.1 0.017 14.0 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 EMC91718.1 - 0.0082 15.4 0.1 0.11 11.7 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 EMC91718.1 - 0.025 15.1 0.1 0.059 13.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EMC91718.1 - 0.027 14.7 0.1 0.27 11.5 0.1 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 EMC91718.1 - 0.15 11.5 0.0 0.89 9.0 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus OTU PF02338.19 EMC91719.1 - 7.2e-11 42.7 0.0 1.6e-10 41.6 0.0 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EMC91719.1 - 0.0034 16.9 0.4 3.6 6.9 0.8 2.8 2 1 1 3 3 3 2 Peptidase C65 Otubain ProRS-C_1 PF09180.11 EMC91721.1 - 1.8e-23 82.5 0.2 3.8e-23 81.5 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EMC91721.1 - 8.7e-18 64.9 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMC91721.1 - 1.3e-14 54.1 0.0 3.8e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Rieske PF00355.26 EMC91722.1 - 2.9e-11 43.2 0.0 1.2e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EMC91722.1 - 2.6e-08 34.2 0.1 7.2e-08 32.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Macro PF01661.21 EMC91723.1 - 7.2e-21 74.4 0.0 1.7e-20 73.2 0.0 1.6 1 1 0 1 1 1 1 Macro domain HEAT_2 PF13646.6 EMC91725.1 - 7.9e-29 99.9 3.8 2.2e-14 53.6 1.1 3.5 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 EMC91725.1 - 7e-19 66.5 4.3 0.0033 17.9 0.3 6.7 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EMC91725.1 - 1.6e-05 24.7 5.6 1.1 9.7 0.0 6.1 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EMC91725.1 - 0.005 17.3 6.2 0.89 10.1 0.0 4.8 2 2 5 7 7 7 2 HEAT-like repeat Arm PF00514.23 EMC91725.1 - 0.13 12.4 0.0 9.7 6.4 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Nipped-B_C PF12830.7 EMC91726.1 - 1.4e-52 178.4 6.2 5.3e-49 166.8 0.9 3.8 3 1 1 4 4 4 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EMC91726.1 - 2e-06 28.0 2.6 7.1e-05 23.0 0.4 3.1 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 EMC91726.1 - 6e-06 26.4 4.6 0.0037 17.3 0.1 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EMC91726.1 - 0.00066 19.7 4.8 0.36 11.2 0.1 5.5 5 0 0 5 5 5 1 HEAT repeat Sin_N PF04801.13 EMC91727.1 - 4.6e-32 111.8 0.4 2.5e-31 109.3 0.3 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region Pox_Ag35 PF03286.14 EMC91727.1 - 0.0079 16.0 2.2 0.013 15.3 2.2 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein PNTB PF02233.16 EMC91728.1 - 9.2e-173 575.4 25.3 9.2e-173 575.4 25.3 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EMC91728.1 - 1.1e-73 247.1 0.2 1.1e-73 247.1 0.2 2.6 4 0 0 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EMC91728.1 - 4.5e-38 130.6 0.0 2e-37 128.5 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EMC91728.1 - 2.4e-30 104.8 3.5 2.4e-30 104.8 3.5 5.2 5 1 0 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EMC91728.1 - 7.8e-05 22.1 0.0 0.72 9.2 0.0 3.4 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 EMC91728.1 - 0.002 17.9 0.2 0.0083 15.9 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CP_ATPgrasp_1 PF04174.13 EMC91728.1 - 0.0061 15.6 0.3 0.045 12.8 0.0 2.1 2 0 0 2 2 2 1 A circularly permuted ATPgrasp NAD_binding_8 PF13450.6 EMC91728.1 - 0.46 10.7 6.8 0.1 12.9 0.4 3.4 3 1 1 4 4 4 0 NAD(P)-binding Rossmann-like domain SKG6 PF08693.10 EMC91729.1 - 7.8e-05 22.0 0.6 0.00018 20.9 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 EMC91729.1 - 0.0093 16.4 6.3 0.0093 16.4 6.3 1.9 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 EMC91729.1 - 0.091 13.7 0.0 0.15 13.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EMC91729.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 EMC91729.1 - 0.34 10.9 1.4 0.63 10.0 1.4 1.3 1 0 0 1 1 1 0 Syndecan domain Ank_2 PF12796.7 EMC91730.1 - 0.014 16.0 0.0 0.024 15.2 0.0 1.4 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) MMS1_N PF10433.9 EMC91732.1 - 1e-133 446.6 0.0 5.2e-133 444.2 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EMC91732.1 - 1.6e-75 254.4 0.0 2.7e-72 243.8 0.0 3.0 3 0 0 3 3 3 2 CPSF A subunit region HPS3_N PF14761.6 EMC91732.1 - 0.021 14.4 1.1 1e+02 2.3 0.0 5.4 7 0 0 7 7 7 0 Hermansky-Pudlak syndrome 3 LVIVD PF08309.11 EMC91732.1 - 0.065 12.6 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 LVIVD repeat DEAD PF00270.29 EMC91733.1 - 1.3e-41 142.3 0.0 4.5e-41 140.5 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC91733.1 - 2.8e-20 72.7 0.0 2.5e-19 69.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMC91733.1 - 1.4e-16 60.4 1.0 9e-16 57.9 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EMC91733.1 - 1.3e-05 25.2 0.0 2.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATP-synt_D PF01813.17 EMC91734.1 - 1.8e-71 240.1 1.1 2.3e-71 239.7 1.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D APG6_N PF17675.1 EMC91734.1 - 0.0036 17.8 2.3 0.0036 17.8 2.3 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF4300 PF14133.6 EMC91734.1 - 0.024 14.3 0.1 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) CLP1_P PF16575.5 EMC91734.1 - 0.15 11.9 0.6 0.34 10.7 0.6 1.7 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Ribosomal_L6e PF01159.19 EMC91734.1 - 0.42 11.2 3.8 1.3 9.6 3.8 1.8 1 0 0 1 1 1 0 Ribosomal protein L6e Mig-14 PF07395.11 EMC91734.1 - 0.62 9.4 4.6 0.19 11.1 0.4 1.9 2 0 0 2 2 2 0 Mig-14 DASH_Spc19 PF08287.11 EMC91734.1 - 4.2 7.2 9.8 9 6.2 5.3 2.3 2 1 0 2 2 2 0 Spc19 GMC_oxred_N PF00732.19 EMC91735.1 - 6e-61 206.4 0.0 1e-60 205.7 0.0 1.3 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC91735.1 - 4.2e-29 101.9 0.0 7.7e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EMC91735.1 - 5.8e-05 23.2 0.6 0.00014 22.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC91735.1 - 0.00015 21.5 0.7 0.00037 20.2 0.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMC91735.1 - 0.00056 19.1 0.1 0.00086 18.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMC91735.1 - 0.00076 18.7 0.2 0.0018 17.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EMC91735.1 - 0.0023 17.2 0.1 0.0047 16.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EMC91735.1 - 0.0024 17.2 0.1 0.97 8.6 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC91735.1 - 0.0098 15.1 0.3 0.041 13.1 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC91735.1 - 0.11 11.2 0.4 0.31 9.7 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein ESR1_C PF12743.7 EMC91736.1 - 2.8 7.8 8.0 7.7 6.4 8.0 1.8 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal PEMT PF04191.13 EMC91737.1 - 1.2e-58 196.1 7.3 5.4e-36 123.2 0.5 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 EMC91737.1 - 0.01 15.6 0.1 0.051 13.4 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 EMC91737.1 - 0.11 13.1 0.1 2.2 8.9 0.1 2.4 1 1 0 1 1 1 0 SKICH domain Mpv17_PMP22 PF04117.12 EMC91737.1 - 0.14 12.4 6.4 0.21 11.9 4.4 2.4 2 0 0 2 2 2 0 Mpv17 / PMP22 family NIR_SIR PF01077.22 EMC91738.1 - 6.5e-52 175.2 0.1 2.8e-45 153.7 0.1 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EMC91738.1 - 3.5e-32 110.1 0.1 4.5e-15 55.3 0.1 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EMC91738.1 - 1.9e-27 96.3 0.0 3.8e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EMC91738.1 - 2.6e-09 37.2 0.0 6.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CTNNBL PF08216.11 EMC91740.1 - 2.9e-38 130.2 0.1 8.2e-38 128.8 0.1 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear MMS19_C PF12460.8 EMC91740.1 - 0.0051 16.0 1.8 0.13 11.3 0.1 2.5 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Mo25 PF08569.11 EMC91740.1 - 0.019 14.3 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Mo25-like HEAT_2 PF13646.6 EMC91740.1 - 0.028 14.8 2.5 0.11 12.8 0.9 2.9 1 1 1 2 2 2 0 HEAT repeats BetR PF08667.10 EMC91740.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 BetR domain Putative_PNPOx PF01243.20 EMC91741.1 - 0.0035 17.5 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AtuA PF07287.11 EMC91742.1 - 7.2e-132 439.4 0.1 8.6e-132 439.1 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Asp PF00026.23 EMC91743.1 - 3.5e-71 240.2 6.0 4.8e-71 239.8 6.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMC91743.1 - 1.7e-06 28.4 5.8 0.015 15.5 0.4 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMC91743.1 - 0.00048 20.7 1.8 0.11 13.1 0.5 3.2 2 1 0 2 2 2 2 Aspartyl protease Peptidase_C48 PF02902.19 EMC91744.1 - 3.7e-13 49.8 0.0 6.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MAT1 PF06391.13 EMC91744.1 - 0.011 15.6 10.3 0.011 15.6 10.3 2.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DASH_Dad3 PF08656.10 EMC91752.1 - 3.3e-28 97.6 0.3 4.3e-28 97.2 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.25 EMC91753.1 - 4.4e-72 242.6 0.0 2e-71 240.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC91753.1 - 3.4e-30 105.2 0.0 4e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EMC91753.1 - 4.3e-06 26.3 0.1 0.55 9.5 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 EMC91753.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMC91753.1 - 0.023 13.5 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EMC91753.1 - 0.024 14.6 0.0 0.36 10.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arrestin_C PF02752.22 EMC91754.1 - 3e-14 53.6 0.0 8.7e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Polysacc_deac_1 PF01522.21 EMC91754.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase Pro_isomerase PF00160.21 EMC91755.1 - 9.5e-48 162.4 0.0 1.1e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Skp1_POZ PF03931.15 EMC91756.1 - 5.1e-08 33.0 0.0 6.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain ThiF PF00899.21 EMC91757.1 - 4.5e-70 235.8 0.0 7.8e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EMC91757.1 - 4.4e-10 40.0 0.2 1.9e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EMC91757.1 - 7.4e-10 39.2 0.1 8.4e-05 22.6 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin-activating enzyme active site Q_salvage PF10343.9 EMC91758.1 - 1.6e-114 382.3 0.0 6.8e-74 249.0 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family SLT PF01464.20 EMC91759.1 - 0.046 13.4 0.1 0.085 12.5 0.1 1.6 1 1 0 1 1 1 0 Transglycosylase SLT domain Rad60-SLD_2 PF13881.6 EMC91760.1 - 1.9e-10 40.8 0.0 3.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UMP1 PF05348.11 EMC91763.1 - 2.2e-39 134.4 0.0 2.9e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 HET PF06985.11 EMC91766.1 - 2.1e-18 67.1 0.0 2.3e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SipA_VBS PF17985.1 EMC91766.1 - 0.076 12.9 0.2 15 5.7 0.1 2.3 2 0 0 2 2 2 0 SipA vinculin binding site NMD3 PF04981.13 EMC91767.1 - 2.4e-79 266.2 1.1 3.2e-79 265.8 1.1 1.2 1 0 0 1 1 1 1 NMD3 family Nif11 PF07862.11 EMC91767.1 - 0.031 14.6 1.6 0.054 13.8 0.1 2.2 2 0 0 2 2 2 0 Nif11 domain HypA PF01155.19 EMC91767.1 - 0.056 13.5 2.8 1.6 8.8 0.2 2.7 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Plasmid_RAQPRD PF09686.10 EMC91767.1 - 0.061 13.5 0.7 0.45 10.8 0.5 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) HscB_4_cys PF18256.1 EMC91767.1 - 0.079 12.8 0.5 0.19 11.5 0.5 1.7 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif DZR PF12773.7 EMC91767.1 - 0.86 9.7 6.7 0.93 9.6 1.2 2.7 1 1 1 2 2 2 0 Double zinc ribbon PAP2 PF01569.21 EMC91768.1 - 4.5e-18 65.3 6.0 1.7e-17 63.5 6.0 2.0 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EMC91768.1 - 0.0033 17.1 6.5 0.0081 15.9 6.5 1.8 1 1 0 1 1 1 1 PAP2 superfamily RNA12 PF10443.9 EMC91768.1 - 0.073 11.8 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 RNA12 protein Ras PF00071.22 EMC91769.1 - 1.3e-48 164.6 0.0 1.7e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC91769.1 - 3.6e-20 72.4 0.0 6.5e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC91769.1 - 3e-05 23.5 0.0 5.4e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EMC91769.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EMC91769.1 - 0.042 13.3 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_6 PF12774.7 EMC91770.1 - 2.8e-125 417.6 0.1 1.1e-123 412.4 0.0 3.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EMC91770.1 - 1.6e-118 396.3 2.6 1.6e-118 396.3 2.6 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EMC91770.1 - 1.7e-100 337.3 0.1 1.7e-100 337.3 0.1 4.1 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 EMC91770.1 - 8.1e-74 247.5 0.3 8.1e-74 247.5 0.3 4.2 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 EMC91770.1 - 2.3e-68 230.3 0.0 7.5e-68 228.7 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 EMC91770.1 - 1.1e-41 143.0 3.7 1.9e-41 142.2 3.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 EMC91770.1 - 1.3e-41 142.1 0.0 4.8e-36 124.0 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 EMC91770.1 - 4.8e-30 104.3 0.1 7e-11 42.3 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EMC91770.1 - 4.5e-28 97.7 0.0 7.8e-25 87.3 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EMC91770.1 - 6.5e-28 97.6 0.0 1.4e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EMC91770.1 - 2.6e-18 66.6 0.0 0.0066 16.7 0.0 7.1 5 1 1 6 6 6 3 AAA domain Dynein_AAA_lid PF17852.1 EMC91770.1 - 2e-15 57.0 0.0 1.9e-14 53.8 0.0 2.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EMC91770.1 - 5.9e-13 49.4 0.0 0.0017 18.8 0.0 5.0 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EMC91770.1 - 1.4e-10 41.5 1.5 0.091 12.9 0.0 6.0 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.6 EMC91770.1 - 3.1e-09 37.4 0.1 0.24 11.9 0.0 5.3 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 EMC91770.1 - 1.9e-07 30.4 0.0 0.0042 16.2 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_16 PF13191.6 EMC91770.1 - 3.8e-06 27.4 11.4 7 7.0 0.0 8.7 10 0 0 10 10 7 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EMC91770.1 - 6.7e-06 25.6 0.1 1.8 7.8 0.1 4.5 4 0 0 4 4 4 2 FtsK/SpoIIIE family AAA_29 PF13555.6 EMC91770.1 - 0.00011 21.9 0.1 3.1 7.6 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EMC91770.1 - 0.00019 21.2 0.7 22 4.7 0.0 5.0 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.6 EMC91770.1 - 0.00022 21.0 0.7 6 6.5 0.0 4.5 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EMC91770.1 - 0.00024 21.6 0.6 6.5 7.3 0.0 4.8 4 0 0 4 4 3 0 ABC transporter Mg_chelatase PF01078.21 EMC91770.1 - 0.00028 20.3 3.3 0.45 9.9 0.0 4.5 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMC91770.1 - 0.00032 20.3 0.2 0.75 9.3 0.0 5.1 4 1 1 5 5 5 1 AAA domain AAA_lid_1 PF17857.1 EMC91770.1 - 0.00041 20.5 0.0 0.0055 16.9 0.0 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_19 PF13245.6 EMC91770.1 - 0.00058 20.2 1.8 0.2 12.0 0.0 4.8 5 0 0 5 5 4 1 AAA domain IstB_IS21 PF01695.17 EMC91770.1 - 0.00077 19.2 1.7 0.42 10.3 0.0 5.1 5 0 0 5 5 5 1 IstB-like ATP binding protein Rad17 PF03215.15 EMC91770.1 - 0.0016 18.4 0.1 5.8 6.8 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain RNA_helicase PF00910.22 EMC91770.1 - 0.018 15.5 0.4 23 5.4 0.0 4.3 4 0 0 4 4 4 0 RNA helicase RsgA_GTPase PF03193.16 EMC91770.1 - 0.035 14.0 0.0 12 5.7 0.0 3.4 3 0 0 3 3 3 0 RsgA GTPase DUF3867 PF12983.7 EMC91770.1 - 0.36 10.9 3.0 24 4.9 0.1 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3867) PduV-EutP PF10662.9 EMC91770.1 - 0.5 10.1 4.3 15 5.3 0.0 4.2 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Taxilin PF09728.9 EMC91770.1 - 0.94 8.6 20.4 0.015 14.5 12.6 2.0 2 0 0 2 2 1 0 Myosin-like coiled-coil protein Spc7 PF08317.11 EMC91770.1 - 3.5 6.4 30.7 0.93 8.3 10.3 3.9 3 0 0 3 3 3 0 Spc7 kinetochore protein BRE1 PF08647.11 EMC91770.1 - 7.5 6.7 20.7 0.041 14.0 2.6 4.5 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Halogen_Hydrol PF10112.9 EMC91770.1 - 9.2 6.2 7.9 2.2 8.3 3.1 2.5 2 0 0 2 2 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SAPIS-gp6 PF16722.5 EMC91771.1 - 0.48 10.9 3.5 0.3 11.5 0.3 2.2 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Methyltransf_33 PF10017.9 EMC91772.1 - 2.2e-94 316.1 0.1 3.1e-94 315.6 0.1 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EMC91772.1 - 4.4e-15 56.0 1.0 2.9e-13 50.0 1.0 2.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EMC91772.1 - 0.024 15.2 1.4 0.066 13.7 1.2 1.9 1 1 0 1 1 1 0 DinB superfamily DUF1598 PF07643.11 EMC91772.1 - 0.04 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) Ribosomal_L23 PF00276.20 EMC91774.1 - 6.5e-06 26.4 0.0 2e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 DUF4786 PF16027.5 EMC91774.1 - 0.038 14.6 0.2 0.049 14.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) Sec7 PF01369.20 EMC91775.1 - 2.8e-65 219.4 0.1 4.4e-65 218.8 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EMC91775.1 - 4.1e-19 69.0 0.0 2.5e-18 66.5 0.0 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EMC91775.1 - 0.17 11.8 0.2 30 4.6 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Zn_clus PF00172.18 EMC91776.1 - 5e-05 23.3 10.2 7.3e-05 22.8 10.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 EMC91776.1 - 0.0017 18.6 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold Sec1 PF00995.23 EMC91777.1 - 6.4e-114 382.3 0.0 7.5e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Alpha-E PF04168.12 EMC91777.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. SUV3_C PF12513.8 EMC91778.1 - 3.4e-18 65.3 0.0 7.8e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EMC91778.1 - 1.5e-10 41.4 0.1 3.3e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EMC91778.1 - 5e-06 26.3 0.0 9.5e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Fungal_trans PF04082.18 EMC91779.1 - 7.6e-27 94.0 0.0 1.4e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC91779.1 - 6.8e-09 35.7 8.1 1.1e-08 35.0 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMC91779.1 - 0.025 13.4 0.9 0.04 12.7 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain GILT PF03227.16 EMC91781.1 - 1.4e-19 70.3 0.1 2.4e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) LptF_LptG PF03739.14 EMC91781.1 - 0.0033 16.3 0.1 0.0045 15.9 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG WD40 PF00400.32 EMC91784.1 - 5.3e-29 99.8 14.6 3.2e-06 27.8 0.1 6.8 7 0 0 7 7 6 5 WD domain, G-beta repeat Nup160 PF11715.8 EMC91784.1 - 4.1e-08 32.3 6.2 0.0027 16.4 0.0 4.8 3 2 1 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EMC91784.1 - 3.8e-07 30.3 0.0 1.1 9.6 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Phage_GP20 PF06810.11 EMC91784.1 - 0.0056 16.5 7.4 0.0097 15.7 7.4 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF5046 PF16465.5 EMC91784.1 - 0.028 13.9 0.3 0.64 9.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) Laminin_II PF06009.12 EMC91784.1 - 0.19 11.8 1.5 0.38 10.8 1.5 1.4 1 0 0 1 1 1 0 Laminin Domain II SKA1 PF07160.12 EMC91784.1 - 0.34 10.7 4.5 0.53 10.1 4.5 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Macoilin PF09726.9 EMC91784.1 - 0.61 8.6 5.3 0.88 8.1 5.3 1.1 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 EMC91784.1 - 0.62 10.1 9.6 0.96 9.5 9.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 EMC91784.1 - 0.94 10.0 15.3 3.1 8.3 15.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Nup88 PF10168.9 EMC91784.1 - 1.1 7.0 5.2 1.6 6.5 5.2 1.1 1 0 0 1 1 1 0 Nuclear pore component AATF-Che1 PF13339.6 EMC91784.1 - 2.5 8.8 5.8 3.8 8.2 4.1 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Spc7 PF08317.11 EMC91784.1 - 3.8 6.3 11.4 6.5 5.5 11.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein IBR PF01485.21 EMC91787.1 - 5.8e-05 23.2 37.2 0.00017 21.8 5.8 3.5 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EMC91787.1 - 4.7 7.6 38.4 0.45 10.9 13.3 4.5 3 2 1 4 4 4 0 Ring finger domain ParA PF10609.9 EMC91788.1 - 3.6e-95 318.1 0.0 4.3e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EMC91788.1 - 2.1e-08 34.3 0.0 7e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMC91788.1 - 7.2e-05 22.8 0.0 0.00024 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EMC91788.1 - 0.0001 21.6 0.5 0.0015 17.7 0.2 2.3 1 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 EMC91788.1 - 0.0067 16.3 0.0 0.75 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMC91788.1 - 0.0068 16.0 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMC91788.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 EMC91788.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.3 1 1 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 EMC91788.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 EMC91788.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Fer4_NifH PF00142.18 EMC91788.1 - 0.03 13.8 0.0 0.62 9.5 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.22 EMC91788.1 - 0.063 13.7 0.1 0.16 12.4 0.1 1.8 1 1 0 1 1 1 0 RNA helicase TsaE PF02367.17 EMC91788.1 - 0.08 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EMC91788.1 - 0.088 13.2 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DnaB_C PF03796.15 EMC91788.1 - 0.17 11.2 0.1 0.25 10.7 0.1 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 EMC91788.1 - 0.18 10.8 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4094 PF13334.6 EMC91790.1 - 0.045 14.2 0.9 0.12 12.8 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) GSCFA PF08885.11 EMC91790.1 - 0.045 13.4 1.9 0.082 12.6 0.5 2.0 2 0 0 2 2 2 0 GSCFA family ABC_tran_CTD PF16326.5 EMC91790.1 - 0.048 13.9 4.8 1.7 9.0 0.3 3.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain JAKMIP_CC3 PF16034.5 EMC91790.1 - 0.073 13.0 4.5 0.14 12.1 4.5 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain TBCA PF02970.16 EMC91790.1 - 0.14 12.5 2.2 0.28 11.6 2.2 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A LsmAD PF06741.13 EMC91790.1 - 0.18 12.3 0.6 0.49 11.0 0.6 1.7 1 0 0 1 1 1 0 LsmAD domain XhlA PF10779.9 EMC91790.1 - 0.65 10.3 2.3 3.2 8.0 1.1 2.1 1 1 1 2 2 2 0 Haemolysin XhlA DUF4764 PF15961.5 EMC91790.1 - 3.3 6.3 9.9 0.25 10.0 3.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) MFS_1 PF07690.16 EMC91793.1 - 2.2e-19 69.6 45.3 1.3e-16 60.5 45.7 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PsbJ PF01788.17 EMC91793.1 - 1.3 9.0 9.7 8.9 6.3 1.9 3.1 2 0 0 2 2 2 0 PsbJ ThiF PF00899.21 EMC91794.1 - 8.2e-111 369.2 0.0 7.8e-76 254.6 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EMC91794.1 - 2.9e-94 315.7 1.1 2.9e-94 315.7 1.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EMC91794.1 - 7.1e-33 112.6 0.1 1.6e-32 111.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EMC91794.1 - 2e-30 105.3 0.2 4.3e-30 104.3 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EMC91794.1 - 3e-26 91.4 0.5 1e-25 89.7 0.5 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 EMC91794.1 - 0.00097 19.6 0.0 0.045 14.2 0.0 3.1 3 0 0 3 3 3 1 Putative NAD(P)-binding Cyclin_N PF00134.23 EMC91795.1 - 6.3e-15 55.0 0.2 2.5e-13 49.9 0.4 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EMC91795.1 - 0.0074 16.3 0.3 0.017 15.2 0.3 1.7 1 1 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 EMC91795.1 - 0.021 15.2 2.2 0.085 13.2 0.3 2.8 2 2 0 2 2 2 0 Cyclin C-terminal domain CHCH PF06747.13 EMC91795.1 - 0.16 12.1 0.3 0.37 11.0 0.3 1.7 1 0 0 1 1 1 0 CHCH domain zf-RING_6 PF14835.6 EMC91795.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Cyclin_C PF02984.19 EMC91795.1 - 0.53 10.4 3.0 8.9 6.4 0.0 3.1 2 1 1 3 3 3 0 Cyclin, C-terminal domain DUF4452 PF14618.6 EMC91797.1 - 5.5e-63 211.9 17.1 1.2e-62 210.8 17.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4452) ADH_zinc_N PF00107.26 EMC91799.1 - 3.3e-30 104.7 1.0 5.2e-30 104.1 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC91799.1 - 4.6e-16 60.1 0.0 8.3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC91799.1 - 3.6e-09 36.5 0.0 1.2e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EMC91799.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF3337 PF11816.8 EMC91801.1 - 1.4e-52 178.0 0.0 3.5e-43 147.4 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 EMC91801.1 - 2e-20 72.8 16.7 3.3e-05 24.5 0.2 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC91801.1 - 0.036 14.4 0.2 4.3 7.7 0.1 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC91801.1 - 0.071 11.7 4.3 0.034 12.8 1.3 2.0 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.11 EMC91801.1 - 0.086 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 EMC91801.1 - 0.091 11.7 0.0 0.47 9.4 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Amidase PF01425.21 EMC91802.1 - 2.1e-68 231.3 0.0 3.3e-68 230.7 0.0 1.3 1 1 0 1 1 1 1 Amidase WD40 PF00400.32 EMC91804.1 - 1e-50 168.6 10.6 6.5e-08 33.1 0.1 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC91804.1 - 2e-27 95.3 0.1 3.1e-06 27.4 0.0 6.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 EMC91804.1 - 3.6e-11 43.6 1.7 6.1e-08 33.1 0.0 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 EMC91804.1 - 6.5e-07 29.4 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.11 EMC91804.1 - 1.4e-06 28.3 0.0 0.2 11.5 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 EMC91804.1 - 1.9e-06 28.4 0.1 5.3e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ge1_WD40 PF16529.5 EMC91804.1 - 1.1e-05 24.6 0.0 1.3 7.9 0.0 5.2 1 1 5 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EMC91804.1 - 2e-05 24.1 0.0 2.5 7.3 0.0 4.6 3 1 3 6 6 6 2 WD40-like domain PD40 PF07676.12 EMC91804.1 - 0.00029 20.7 0.6 30 4.7 0.0 6.1 7 0 0 7 7 6 0 WD40-like Beta Propeller Repeat APS_kinase PF01583.20 EMC91804.1 - 0.0011 18.9 0.1 0.002 18.0 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Nbas_N PF15492.6 EMC91804.1 - 0.0023 17.3 0.1 15 4.8 0.1 4.3 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal NB-ARC PF00931.22 EMC91804.1 - 0.0039 16.4 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 EMC91804.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMC91804.1 - 0.036 14.6 0.0 0.12 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMC91804.1 - 0.036 14.4 0.0 0.14 12.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_22 PF13401.6 EMC91804.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EMC91804.1 - 0.059 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 EMC91804.1 - 0.067 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EMC91804.1 - 0.12 12.3 0.0 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 NTPase Ret2_MD PF18528.1 EMC91804.1 - 0.15 12.4 0.0 30 5.1 0.0 3.7 4 1 1 5 5 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Thymidylate_kin PF02223.17 EMC91804.1 - 0.17 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase Proteasome_A_N PF10584.9 EMC91804.1 - 0.17 11.6 0.2 13 5.6 0.0 3.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature FAD_binding_3 PF01494.19 EMC91806.1 - 3.6e-12 46.2 0.0 5.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC91806.1 - 0.034 13.4 0.2 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EMC91806.1 - 0.23 10.4 0.1 2.9 6.9 0.0 2.2 2 1 0 2 2 2 0 Squalene epoxidase Thr_synth_N PF14821.6 EMC91807.1 - 2.6e-29 101.2 0.0 7.1e-29 99.8 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EMC91807.1 - 2.3e-17 63.4 0.0 5.5e-17 62.1 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme BLUF PF04940.12 EMC91807.1 - 0.12 12.5 0.0 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 Sensors of blue-light using FAD DUF3402 PF11882.8 EMC91808.1 - 7.2 5.6 7.1 9 5.3 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Abhydrolase_6 PF12697.7 EMC91809.1 - 0.03 14.9 0.0 0.038 14.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family CorA PF01544.18 EMC91810.1 - 0.002 17.5 5.4 0.029 13.7 5.4 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Myb_DNA-binding PF00249.31 EMC91812.1 - 0.028 14.6 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain PHD PF00628.29 EMC91813.1 - 3e-07 30.2 5.1 6.4e-07 29.2 5.1 1.6 1 0 0 1 1 1 1 PHD-finger APH PF01636.23 EMC91813.1 - 1.9e-05 24.7 1.1 0.0047 16.9 1.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EMC91813.1 - 7.2e-05 22.3 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EMC91813.1 - 0.00013 21.6 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.11 EMC91813.1 - 0.008 15.8 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) zf-HC5HC2H PF13771.6 EMC91813.1 - 0.092 13.0 1.4 0.22 11.8 1.4 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 EMC91813.1 - 0.16 11.5 1.0 0.38 10.3 1.0 1.6 1 0 0 1 1 1 0 PHD-finger ROKNT PF08067.11 EMC91813.1 - 0.21 11.9 1.3 0.52 10.6 1.3 1.6 1 0 0 1 1 1 0 ROKNT (NUC014) domain Pyridox_oxase_2 PF12766.7 EMC91814.1 - 1.2e-19 70.7 0.0 2.4e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SET PF00856.28 EMC91815.1 - 1.7e-13 51.3 0.1 6.5e-13 49.4 0.0 2.1 2 1 0 2 2 2 1 SET domain PAM2 PF07145.15 EMC91815.1 - 0.04 13.6 0.4 0.11 12.2 0.4 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Myc_target_1 PF15179.6 EMC91815.1 - 5.7 6.8 9.6 14 5.6 9.5 1.7 1 1 0 1 1 1 0 Myc target protein 1 RIO1 PF01163.22 EMC91816.1 - 1.4e-39 135.7 0.0 3.3e-39 134.4 0.0 1.6 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EMC91816.1 - 1.2e-31 108.8 0.0 2.4e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 EMC91816.1 - 1.2e-05 24.7 0.1 0.012 15.0 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMC91816.1 - 1.4e-05 25.1 2.9 0.087 12.7 0.0 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family CDC45 PF02724.14 EMC91816.1 - 6.9 4.8 7.1 9.3 4.4 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pmp3 PF01679.17 EMC91817.1 - 4e-20 71.7 7.9 5.1e-20 71.4 7.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Voltage_CLC PF00654.20 EMC91818.1 - 1.2e-89 301.1 26.4 1.2e-89 301.1 26.4 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EMC91818.1 - 7.8e-12 45.5 0.1 3.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain RPN1_RPN2_N PF17781.1 EMC91819.1 - 2.8e-120 401.4 2.6 4.3e-120 400.8 2.6 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EMC91819.1 - 6.4e-27 93.4 0.0 1.1e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EMC91819.1 - 5.6e-16 58.1 24.2 1.9e-07 31.2 0.6 8.0 9 1 0 9 9 9 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EMC91819.1 - 4.9e-08 33.2 1.0 0.0056 17.0 0.0 4.9 5 1 1 6 6 6 3 HEAT repeats OB_NTP_bind PF07717.16 EMC91820.1 - 1.8e-24 85.9 0.0 5.1e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EMC91820.1 - 2.8e-18 66.1 0.1 6.4e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMC91820.1 - 4.3e-10 39.9 0.0 1.1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMC91820.1 - 8.1e-08 32.2 0.3 1.7e-07 31.2 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMC91820.1 - 3.2e-05 24.2 0.0 9.3e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EMC91820.1 - 0.00097 18.8 0.4 0.004 16.8 0.4 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EMC91820.1 - 0.0045 16.7 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMC91820.1 - 0.0047 17.3 0.2 0.0097 16.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EMC91820.1 - 0.005 16.8 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_7 PF12775.7 EMC91820.1 - 0.058 12.9 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EMC91820.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EMC91820.1 - 0.077 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMC91820.1 - 0.12 12.8 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Glyco_transf_17 PF04724.13 EMC91821.1 - 1.8e-49 168.6 0.3 6.1e-48 163.6 0.3 2.6 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF72 PF01904.18 EMC91821.1 - 0.057 13.5 0.1 0.16 12.1 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function DUF72 Joubert PF15392.6 EMC91822.1 - 0.11 12.2 3.5 0.12 12.1 3.5 1.0 1 0 0 1 1 1 0 Joubert syndrome-associated zf-U1 PF06220.12 EMC91823.1 - 0.028 14.2 0.3 0.058 13.2 0.3 1.5 1 0 0 1 1 1 0 U1 zinc finger HET PF06985.11 EMC91824.1 - 1.6e-25 90.1 0.0 2.8e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EMC91825.1 - 1.5e-33 115.3 4.7 5e-07 30.2 0.0 6.9 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC91825.1 - 3.6e-23 81.6 4.0 0.00077 20.0 0.2 7.9 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMC91825.1 - 6.9e-22 77.2 8.3 7.1e-05 23.0 0.1 7.6 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EMC91825.1 - 4.7e-21 74.2 11.7 0.0059 17.0 0.0 11.4 11 0 0 11 11 11 4 Ankyrin repeat Ank_3 PF13606.6 EMC91825.1 - 9.4e-21 71.7 7.8 0.019 15.5 0.0 10.3 11 0 0 11 11 10 5 Ankyrin repeat NACHT PF05729.12 EMC91825.1 - 6.3e-07 29.5 0.0 1.8e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMC91825.1 - 0.00025 21.4 0.0 0.0013 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC91825.1 - 0.00092 19.6 0.2 0.00092 19.6 0.2 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 EMC91825.1 - 0.024 15.1 0.0 0.075 13.5 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMC91825.1 - 0.033 14.6 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Zn_Tnp_IS91 PF14319.6 EMC91825.1 - 2.1 8.5 7.3 26 4.9 4.5 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain Peptidase_S41 PF03572.18 EMC91826.1 - 2.2e-06 27.4 0.0 5.4e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Bromodomain PF00439.25 EMC91826.1 - 0.089 12.9 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 Bromodomain WD40 PF00400.32 EMC91828.1 - 0.22 12.5 0.6 14 6.7 0.1 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat NICE-1 PF15845.5 EMC91830.1 - 0.028 15.2 4.7 0.49 11.2 1.6 2.2 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family MFS_1 PF07690.16 EMC91832.1 - 5.7e-42 143.9 34.8 5.7e-42 143.9 34.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC91832.1 - 4.6e-14 52.1 5.5 4.6e-14 52.1 5.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMC91832.1 - 4.9e-09 35.1 2.0 7.2e-09 34.6 2.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4179 PF13786.6 EMC91832.1 - 0.65 10.5 2.9 22 5.6 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) OATP PF03137.20 EMC91832.1 - 0.81 7.9 5.6 3.3 5.9 5.5 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Mito_carr PF00153.27 EMC91833.1 - 1.4e-47 159.6 7.9 1.8e-19 69.5 0.2 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EMC91833.1 - 0.0022 17.2 1.1 0.094 11.9 0.1 2.4 2 1 0 2 2 2 2 Gammaproteobacterial serine protease Pro-kuma_activ PF09286.11 EMC91834.1 - 3.3e-38 131.2 0.3 7e-38 130.1 0.1 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMC91834.1 - 6.2e-06 25.7 0.7 9.8e-06 25.0 0.7 1.2 1 0 0 1 1 1 1 Subtilase family Metallophos PF00149.28 EMC91835.1 - 3.3e-34 119.2 0.0 1.4e-29 104.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EMC91835.1 - 0.0093 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain LRR_4 PF12799.7 EMC91837.1 - 4.2e-20 71.5 29.9 0.00019 21.8 2.6 7.6 7 0 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMC91837.1 - 9.5e-19 66.9 28.9 6.2e-09 35.5 3.5 6.5 4 2 3 7 7 7 5 Leucine rich repeat LRR_9 PF14580.6 EMC91837.1 - 2.5e-05 23.9 7.5 0.082 12.4 0.7 3.9 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EMC91837.1 - 0.00039 20.2 17.9 2 8.7 0.4 7.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EMC91837.1 - 0.77 10.5 24.5 20 6.2 0.3 8.6 9 1 0 9 9 9 0 Leucine Rich Repeat Lon_C PF05362.13 EMC91839.1 - 1.8e-68 230.1 0.6 3.7e-68 229.1 0.6 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EMC91839.1 - 6.8e-31 107.8 0.1 1.6e-30 106.5 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EMC91839.1 - 2.9e-24 86.0 0.0 1.8e-23 83.5 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMC91839.1 - 2.2e-08 34.2 0.0 9.5e-08 32.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EMC91839.1 - 1.7e-07 31.1 0.0 3.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EMC91839.1 - 3.6e-05 24.2 0.0 3.6e-05 24.2 0.0 3.0 4 1 0 4 4 3 1 AAA ATPase domain TIP49 PF06068.13 EMC91839.1 - 5.2e-05 22.6 0.1 9.8e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EMC91839.1 - 6.8e-05 22.7 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EMC91839.1 - 0.00011 22.1 0.0 0.0004 20.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMC91839.1 - 0.00032 20.5 0.2 0.0018 18.0 0.0 2.3 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMC91839.1 - 0.00036 20.7 0.0 0.0011 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMC91839.1 - 0.00053 20.3 0.0 0.0062 16.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMC91839.1 - 0.0014 18.8 0.0 0.0043 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMC91839.1 - 0.012 15.4 0.6 0.086 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMC91839.1 - 0.016 14.8 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EMC91839.1 - 0.02 14.3 0.1 0.051 12.9 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EMC91839.1 - 0.032 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EMC91839.1 - 0.035 14.5 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 EMC91839.1 - 0.035 13.5 0.0 0.091 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 EMC91839.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMC91839.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMC91839.1 - 0.05 14.2 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMC91839.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EMC91839.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EMC91839.1 - 0.058 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_PrkA PF08298.11 EMC91839.1 - 0.073 12.0 0.1 0.75 8.6 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain Zeta_toxin PF06414.12 EMC91839.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EMC91839.1 - 0.13 12.8 0.0 0.13 12.8 0.0 3.0 1 1 1 2 2 1 0 AAA domain AAA_24 PF13479.6 EMC91839.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MT-A70 PF05063.14 EMC91840.1 - 1.6e-30 106.3 0.0 2.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Mito_carr PF00153.27 EMC91841.1 - 2.5e-60 200.4 1.8 1.5e-21 76.1 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Smg4_UPF3 PF03467.15 EMC91842.1 - 5.7e-34 117.6 0.0 5.7e-34 117.6 0.0 2.2 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 EMC91842.1 - 0.0026 17.5 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GREB1 PF15782.5 EMC91842.1 - 8.6 3.3 9.5 10 3.0 9.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MIP PF00230.20 EMC91843.1 - 1e-48 166.0 16.9 1.2e-48 165.9 16.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Kinesin PF00225.23 EMC91845.1 - 1e-89 300.8 6.6 1.2e-89 300.6 0.0 3.7 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EMC91845.1 - 5.8e-19 68.5 11.6 5.7e-16 58.8 0.0 5.3 5 1 1 6 6 6 2 Microtubule binding Spc29 PF17082.5 EMC91845.1 - 0.0024 17.8 11.8 0.0024 17.8 11.8 7.1 5 2 1 7 7 7 1 Spindle Pole Component 29 ERM PF00769.19 EMC91845.1 - 0.0026 17.6 28.1 0.0026 17.6 28.1 8.6 4 1 3 7 7 7 1 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 EMC91845.1 - 0.012 15.6 0.4 0.012 15.6 0.4 13.2 11 2 2 13 13 13 0 TATA element modulatory factor 1 DNA binding Phage_TAC_12 PF12363.8 EMC91845.1 - 0.024 15.1 1.5 0.1 13.1 1.5 2.1 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Ribosomal_S5_C PF03719.15 EMC91846.1 - 3.9e-21 74.3 0.1 8.8e-21 73.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EMC91846.1 - 7.3e-17 61.1 0.1 1.6e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Het-C PF07217.11 EMC91847.1 - 2e-262 871.8 0.0 2.4e-262 871.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C CAF20 PF17052.5 EMC91848.1 - 0.12 12.5 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Cap associated factor XAP5 PF04921.14 EMC91849.1 - 5.8e-84 281.8 0.0 8.1e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 XAP5, circadian clock regulator Dicty_REP PF05086.12 EMC91849.1 - 1.2 7.0 7.0 1.6 6.6 7.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.11 EMC91849.1 - 8.7 4.3 10.0 0.27 9.3 3.4 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen HAD_2 PF13419.6 EMC91850.1 - 2.8e-14 53.6 0.0 4.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMC91850.1 - 8.3e-06 26.2 0.0 1.1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC91850.1 - 0.0007 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Snf7 PF03357.21 EMC91851.1 - 1.1e-22 80.5 4.6 1.9e-22 79.7 4.6 1.4 1 0 0 1 1 1 1 Snf7 CRR7 PF12095.8 EMC91851.1 - 0.26 11.8 3.1 0.83 10.1 0.1 2.9 2 1 2 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 CS PF04969.16 EMC91852.1 - 8.3e-08 33.1 0.1 1.4e-07 32.4 0.1 1.4 1 0 0 1 1 1 1 CS domain HSP20 PF00011.21 EMC91852.1 - 0.037 14.2 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family TPR_1 PF00515.28 EMC91853.1 - 1.6e-09 37.2 0.0 0.0011 18.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC91853.1 - 6.8e-07 28.9 0.0 0.07 13.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMC91853.1 - 1.7e-06 28.2 0.0 4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMC91853.1 - 3.6e-05 23.3 0.0 0.00012 21.7 0.0 1.9 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.6 EMC91853.1 - 0.00048 20.1 0.0 0.012 15.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMC91853.1 - 0.0019 18.1 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat RXT2_N PF08595.11 EMC91853.1 - 0.0051 16.9 0.9 0.0051 16.9 0.9 1.9 2 0 0 2 2 2 1 RXT2-like, N-terminal TPR_19 PF14559.6 EMC91853.1 - 0.011 16.2 0.0 0.011 16.2 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 EMC91853.1 - 0.3 11.5 7.4 0.72 10.3 7.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EMC91853.1 - 1.8 8.2 4.2 0.96 9.1 0.5 2.1 2 0 0 2 2 2 0 FAM176 family TT_ORF2 PF02957.15 EMC91853.1 - 2 9.4 10.6 0.088 13.7 1.9 2.6 3 0 0 3 3 3 0 TT viral ORF2 NOA36 PF06524.12 EMC91853.1 - 5.4 6.3 6.5 9.9 5.4 6.5 1.4 1 0 0 1 1 1 0 NOA36 protein Mre11_DNA_bind PF04152.14 EMC91854.1 - 1.4e-53 181.6 1.5 1.4e-53 181.6 1.5 2.2 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EMC91854.1 - 3.1e-14 53.9 1.3 6e-14 53.0 1.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMC91854.1 - 0.00018 21.8 0.0 0.0017 18.6 0.0 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF4449 PF14613.6 EMC91854.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4449) Abhydrolase_3 PF07859.13 EMC91855.1 - 8.1e-50 169.6 0.1 9.8e-50 169.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC91855.1 - 0.00037 19.5 0.2 0.0024 16.8 0.1 2.1 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EMC91855.1 - 0.005 16.3 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EMC91855.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase adh_short_C2 PF13561.6 EMC91857.1 - 4.9e-47 160.4 0.1 6.3e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC91857.1 - 1.9e-39 135.1 0.2 2.5e-39 134.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC91857.1 - 7.5e-09 35.7 0.1 1.2e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMC91857.1 - 0.0015 18.0 0.0 0.0031 16.9 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMC91857.1 - 0.0021 17.6 0.1 0.0048 16.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC91857.1 - 0.0026 17.0 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMC91857.1 - 0.027 13.9 0.1 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMC91857.1 - 0.056 12.5 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain FimA PF16970.5 EMC91857.1 - 0.067 13.4 0.2 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 Type-1 fimbrial protein, A THF_DHG_CYH_C PF02882.19 EMC91857.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain tRNA_bind PF01588.20 EMC91860.1 - 6.4e-22 77.5 0.3 2e-21 75.9 0.0 2.0 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C_2 PF13410.6 EMC91860.1 - 3.9e-08 33.2 0.0 8.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC91860.1 - 1.1e-05 25.6 0.0 1.1e-05 25.6 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EMC91860.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NUDIX PF00293.28 EMC91862.1 - 3.6e-26 91.7 0.0 5.4e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MCM PF00493.23 EMC91863.1 - 8.1e-102 339.1 0.3 1.2e-101 338.5 0.3 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMC91863.1 - 8.1e-39 132.3 0.3 1.5e-38 131.5 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EMC91863.1 - 1.7e-31 108.6 1.1 3.6e-31 107.6 1.1 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EMC91863.1 - 7.7e-25 87.1 0.2 1.7e-24 86.0 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMC91863.1 - 7.4e-22 77.9 0.1 3.1e-21 75.9 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMC91863.1 - 3.2e-08 33.2 0.0 8.2e-07 28.6 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EMC91863.1 - 0.00044 20.1 0.0 0.0028 17.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMC91863.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EMC91863.1 - 0.011 15.8 0.0 0.03 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Linker_histone PF00538.19 EMC91863.1 - 0.076 13.4 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 linker histone H1 and H5 family RRM_1 PF00076.22 EMC91864.1 - 8.1e-29 99.3 0.0 1.9e-14 53.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EMC91864.1 - 0.00065 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 ETC_C1_NDUFA4 PF04800.12 EMC91865.1 - 2.2e-35 120.8 3.6 3e-35 120.3 3.6 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 EMC91866.1 - 6.2e-38 129.2 0.1 6.9e-38 129.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 EMC91866.1 - 0.0058 17.0 0.1 0.0064 16.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Ammonium_transp PF00909.21 EMC91868.1 - 1.4e-110 369.7 22.3 1.7e-110 369.5 22.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family FAD_binding_1 PF00667.20 EMC91869.1 - 2.8e-62 210.2 0.0 4.4e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EMC91869.1 - 1.2e-32 113.0 1.6 3.2e-32 111.7 1.6 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EMC91869.1 - 9.2e-22 77.8 0.0 6.5e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Acetyltransf_7 PF13508.7 EMC91870.1 - 0.00016 22.0 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC91870.1 - 0.01 16.1 0.1 0.022 15.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC91870.1 - 0.034 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMC91870.1 - 0.044 13.9 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EMC91870.1 - 0.07 13.2 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Vg_Tdu PF07545.14 EMC91872.1 - 0.14 12.0 0.2 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Vestigial/Tondu family Glyco_hydro_1 PF00232.18 EMC91873.1 - 2e-103 346.2 0.5 2.4e-103 346.0 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Mersacidin PF16934.5 EMC91873.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) PPR_3 PF13812.6 EMC91874.1 - 4.3e-37 126.0 0.0 0.00014 21.8 0.0 9.5 6 3 4 10 10 10 8 Pentatricopeptide repeat domain PPR_2 PF13041.6 EMC91874.1 - 1e-35 121.7 0.0 1.8e-08 34.4 0.0 12.8 11 4 5 16 16 16 7 PPR repeat family PPR PF01535.20 EMC91874.1 - 3.9e-21 73.8 12.3 0.0027 17.8 0.1 13.2 16 0 0 16 16 16 4 PPR repeat PPR_1 PF12854.7 EMC91874.1 - 1.8e-17 62.7 0.0 8.6e-06 25.4 0.0 9.2 9 0 0 9 9 9 3 PPR repeat PPR_long PF17177.4 EMC91874.1 - 2.1e-14 53.4 11.3 1.8e-07 30.8 0.0 6.7 4 3 3 7 7 7 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EMC91874.1 - 2.6e-07 31.0 0.0 9.2e-06 26.1 0.0 3.5 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) APP_E2 PF12925.7 EMC91874.1 - 0.031 14.0 2.1 3.6 7.3 0.1 3.5 4 0 0 4 4 4 0 E2 domain of amyloid precursor protein MukF_C PF17193.4 EMC91874.1 - 0.059 13.5 0.4 9.4 6.4 0.0 3.1 3 0 0 3 3 3 0 MukF C-terminal domain TPR_14 PF13428.6 EMC91874.1 - 1.3 10.0 9.7 62 4.8 0.0 6.8 6 2 1 7 7 7 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 EMC91875.1 - 3.6e-17 62.4 1.3 9e-17 61.1 1.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMC91875.1 - 8.1e-09 35.7 0.0 2.2e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Mfa1 PF17445.2 EMC91875.1 - 6.6 6.8 6.6 13 5.9 0.4 3.2 3 0 0 3 3 3 0 Mating factor A1 Amidohydro_2 PF04909.14 EMC91877.1 - 3.3e-50 171.5 0.1 4e-50 171.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase OmdA PF13376.6 EMC91877.1 - 0.15 12.1 0.7 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated adh_short_C2 PF13561.6 EMC91878.1 - 2.6e-51 174.5 1.2 3.9e-51 173.9 1.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC91878.1 - 2.7e-43 147.7 0.8 2.7e-43 147.7 0.8 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMC91878.1 - 9.8e-08 32.1 0.6 3.2e-07 30.4 0.6 1.7 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 EMC91878.1 - 0.094 13.4 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PQ-loop PF04193.14 EMC91881.1 - 2.4e-17 62.5 6.0 3.1e-10 39.7 1.0 3.2 4 1 0 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 EMC91881.1 - 0.016 16.0 0.8 0.043 14.6 0.4 1.9 1 1 1 2 2 2 0 ER lumen protein retaining receptor Oxidored_q3 PF00499.20 EMC91881.1 - 0.088 12.5 4.0 0.34 10.6 1.6 2.8 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2070 PF09843.9 EMC91881.1 - 0.091 11.0 2.9 0.12 10.7 2.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2207 PF09972.9 EMC91881.1 - 5.4 5.7 7.7 0.6 8.8 1.3 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) UNC45-central PF11701.8 EMC91882.1 - 3.4e-39 134.2 0.7 2.4e-37 128.2 0.7 3.2 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central PaaX PF07848.12 EMC91882.1 - 0.052 13.8 0.4 0.16 12.2 0.2 1.9 2 0 0 2 2 2 0 PaaX-like protein MFS_1 PF07690.16 EMC91884.1 - 2.4e-19 69.5 51.8 1.6e-11 43.8 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Esterase_phd PF10503.9 EMC91884.1 - 0.092 12.2 0.2 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase TPR_21 PF09976.9 EMC91884.1 - 0.19 11.4 0.1 0.3 10.8 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF3099 PF11298.8 EMC91884.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3099) PEN-2 PF10251.9 EMC91884.1 - 3.3 8.2 7.4 0.72 10.3 0.1 3.1 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase CPSase_L_D2 PF02786.17 EMC91885.1 - 1.6e-112 374.1 0.1 7.3e-84 280.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 EMC91885.1 - 1.1e-47 162.3 0.0 2.7e-47 161.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EMC91885.1 - 1.8e-45 154.6 0.0 3.3e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.22 EMC91885.1 - 4.4e-44 149.4 0.0 9.1e-44 148.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 EMC91885.1 - 2.2e-40 137.8 0.2 5.7e-40 136.5 0.2 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EMC91885.1 - 3.1e-30 105.3 0.0 6.5e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 EMC91885.1 - 5.3e-19 68.6 0.2 1.3e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EMC91885.1 - 9.2e-17 61.0 0.0 4e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 EMC91885.1 - 8.1e-16 58.1 0.0 5e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EMC91885.1 - 2.7e-10 40.1 0.0 0.00043 20.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EMC91885.1 - 3.1e-07 30.6 0.2 0.033 14.2 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 EMC91885.1 - 1.5e-05 24.9 0.2 0.015 15.1 0.0 4.1 4 0 0 4 4 4 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 EMC91885.1 - 7.2e-05 22.6 0.1 0.0064 16.3 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 Phage_attach PF05354.11 EMC91885.1 - 0.0041 17.0 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 1 Phage Head-Tail Attachment GARS_A PF01071.19 EMC91885.1 - 0.0049 16.7 0.1 1.5 8.6 0.0 2.8 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EMC91885.1 - 0.0073 15.9 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ID PF18543.1 EMC91885.1 - 0.11 12.5 0.0 15 5.7 0.0 3.1 3 0 0 3 3 3 0 Intracellular delivery domain HET PF06985.11 EMC91886.1 - 1.4e-29 103.3 1.9 2.4e-29 102.5 1.9 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4336 PF14234.6 EMC91890.1 - 0.039 13.1 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Abhydrolase_3 PF07859.13 EMC91891.1 - 3.3e-37 128.4 0.0 4.3e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC91891.1 - 0.027 13.3 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Peptidase_S9 PF00326.21 EMC91891.1 - 0.15 11.5 0.0 21 4.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family HD PF01966.22 EMC91892.1 - 7.4e-07 29.4 0.4 1.2e-06 28.7 0.4 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EMC91892.1 - 0.00048 19.7 0.1 0.001 18.6 0.1 1.6 1 1 1 2 2 2 1 HDOD domain HD_4 PF13328.6 EMC91892.1 - 0.0055 16.5 0.1 0.0084 15.9 0.1 1.3 1 0 0 1 1 1 1 HD domain MIOX PF05153.15 EMC91892.1 - 0.0062 16.1 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase DUF732 PF05305.14 EMC91892.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF732) Pyr_redox_2 PF07992.14 EMC91893.1 - 9.3e-14 51.3 0.0 2.2e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMC91893.1 - 6.6e-08 31.4 0.0 1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMC91893.1 - 2.7e-07 30.1 0.0 4e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC91893.1 - 3.4e-07 30.4 0.0 1e-05 25.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMC91893.1 - 0.00013 21.2 0.0 0.0017 17.5 0.0 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 EMC91893.1 - 0.00018 20.7 0.0 0.0025 17.0 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMC91893.1 - 0.084 12.9 1.3 0.34 10.9 0.0 2.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMC91893.1 - 0.1 13.2 0.0 21 5.7 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PhyH PF05721.13 EMC91894.1 - 7.4e-24 85.2 0.0 1e-23 84.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 EMC91894.1 - 0.0027 18.6 0.0 0.005 17.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EMC91894.1 - 0.0031 17.9 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.24 EMC91895.1 - 2.7e-38 132.0 32.2 4.4e-25 88.4 11.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMC91895.1 - 1.6e-22 79.9 36.8 1.1e-11 44.2 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PDR_CDR PF06422.12 EMC91895.1 - 0.23 11.4 1.3 2.1 8.3 0.3 2.5 2 0 0 2 2 2 0 CDR ABC transporter zf-HIT PF04438.16 EMC91896.1 - 5.6e-09 35.7 13.3 9.1e-09 35.0 13.3 1.4 1 0 0 1 1 1 1 HIT zinc finger DENN PF02141.21 EMC91897.1 - 3.2e-39 134.8 0.1 5.4e-39 134.1 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EMC91897.1 - 2e-05 25.2 0.0 6.4e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.11 EMC91897.1 - 0.0089 16.5 5.0 0.034 14.7 5.0 2.0 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF724 PF05266.14 EMC91897.1 - 5.1 6.9 10.4 14 5.5 10.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) zf-RING_5 PF14634.6 EMC91898.1 - 4.7e-08 32.9 5.5 8.3e-08 32.1 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EMC91898.1 - 0.00015 21.6 4.7 0.00025 20.8 4.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EMC91898.1 - 0.0002 21.7 2.6 0.00038 20.7 2.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EMC91898.1 - 0.00061 19.6 5.4 0.0012 18.7 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF641 PF04859.12 EMC91898.1 - 0.00089 19.6 1.4 0.0022 18.3 0.1 2.0 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) DUF4472 PF14739.6 EMC91898.1 - 0.0009 19.9 6.7 0.0012 19.5 6.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) zf-RING_UBOX PF13445.6 EMC91898.1 - 0.0025 17.8 0.6 0.0053 16.8 0.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EMC91898.1 - 0.0029 17.4 5.6 0.0054 16.6 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC91898.1 - 0.0042 16.9 3.0 0.017 14.9 3.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Lebercilin PF15619.6 EMC91898.1 - 0.0056 16.4 7.7 0.0077 15.9 7.7 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease CENP-H PF05837.12 EMC91898.1 - 0.012 16.0 5.5 0.019 15.3 5.5 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-RING_6 PF14835.6 EMC91898.1 - 0.016 15.1 2.1 0.031 14.1 2.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TMF_TATA_bd PF12325.8 EMC91898.1 - 0.02 15.1 4.8 0.03 14.5 4.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 EMC91898.1 - 0.023 15.3 4.3 0.037 14.7 4.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DZR PF12773.7 EMC91898.1 - 0.036 14.1 3.5 0.13 12.4 3.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon Mito_carr PF00153.27 EMC91898.1 - 0.087 12.8 0.2 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial carrier protein zf-C3HC4_4 PF15227.6 EMC91898.1 - 0.13 12.5 4.0 0.22 11.7 3.5 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Exonuc_VII_L PF02601.15 EMC91898.1 - 0.13 11.8 3.0 0.15 11.6 3.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 EMC91898.1 - 0.13 12.6 10.5 0.21 11.9 10.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 EMC91898.1 - 0.22 12.1 10.0 0.32 11.5 10.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 EMC91898.1 - 0.22 10.1 3.5 0.28 9.7 3.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A IBR PF01485.21 EMC91898.1 - 0.53 10.6 5.6 6.8 7.0 3.1 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 EMC91898.1 - 1.2 9.3 5.9 2.5 8.3 5.9 1.6 1 0 0 1 1 1 0 FYVE zinc finger DASH_Dam1 PF08653.10 EMC91898.1 - 1.4 8.7 4.2 10 6.0 0.3 3.1 1 1 2 3 3 3 0 DASH complex subunit Dam1 Ribosomal_S19 PF00203.21 EMC91899.1 - 2.3e-27 94.7 0.0 2.7e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 adh_short PF00106.25 EMC91901.1 - 4.9e-14 52.3 0.0 5.2e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMC91901.1 - 8.2e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMC91901.1 - 3.3e-05 23.5 0.0 0.00015 21.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMC91901.1 - 7.9e-05 22.2 0.1 0.00035 20.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC91901.1 - 0.027 13.9 0.2 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ABC_tran PF00005.27 EMC91902.1 - 8.3e-20 71.7 0.0 4.3e-10 40.3 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMC91902.1 - 4.8e-07 29.9 2.0 0.0027 17.5 0.1 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EMC91902.1 - 8.8e-05 22.7 0.1 0.12 12.6 0.1 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EMC91902.1 - 0.022 15.3 0.8 0.038 14.5 0.8 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMC91902.1 - 0.096 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EMC91902.1 - 0.16 12.2 0.3 0.98 9.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMC91902.1 - 0.17 11.4 0.7 13 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain NAD_binding_2 PF03446.15 EMC91903.1 - 1.6e-38 132.4 0.2 2.5e-38 131.7 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMC91903.1 - 1.2e-25 90.1 0.0 1.9e-24 86.3 0.0 2.3 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EMC91903.1 - 5.4e-05 23.7 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 EMC91903.1 - 0.0035 18.2 0.0 0.0063 17.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.19 EMC91903.1 - 0.0061 17.2 0.1 0.014 16.1 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain TRAPPC-Trs85 PF12739.7 EMC91905.1 - 8.9e-115 383.9 0.1 5e-113 378.1 0.1 2.1 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Tti2 PF10521.9 EMC91906.1 - 4.7e-64 216.6 2.5 9.6e-64 215.6 2.5 1.5 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 EMC91906.1 - 2.1e-22 79.9 3.0 3.2e-21 76.1 3.0 2.5 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EMC91906.1 - 1.1e-06 28.3 0.0 3.4e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EMC91906.1 - 0.00071 19.6 0.1 0.0021 18.1 0.0 1.8 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative Fungal_trans PF04082.18 EMC91907.1 - 4e-44 150.6 0.0 6.3e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC91907.1 - 1.5e-08 34.6 7.6 3.1e-08 33.6 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup54 PF13874.6 EMC91909.1 - 0.011 15.9 2.8 0.013 15.6 2.8 1.0 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF5333 PF17267.2 EMC91909.1 - 0.019 15.1 0.5 0.1 12.8 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5333) Uso1_p115_C PF04871.13 EMC91909.1 - 0.022 15.1 1.1 0.024 15.0 1.1 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Glutaminase PF04960.15 EMC91909.1 - 0.17 11.0 0.2 0.18 10.9 0.2 1.0 1 0 0 1 1 1 0 Glutaminase bZIP_1 PF00170.21 EMC91909.1 - 0.2 11.8 9.1 0.75 9.9 9.1 1.9 1 1 0 1 1 1 0 bZIP transcription factor TPR_12 PF13424.6 EMC91910.1 - 2.3e-26 91.9 18.3 2.4e-10 40.6 2.7 4.6 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 EMC91910.1 - 4.3e-18 64.6 13.2 3.3e-06 26.8 0.2 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMC91910.1 - 3.6e-14 53.0 8.5 5.6e-06 26.8 1.1 5.3 3 1 2 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 EMC91910.1 - 6.1e-11 42.0 0.2 1.2e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 NB-ARC domain HET PF06985.11 EMC91910.1 - 3.6e-10 40.4 5.9 2.7e-08 34.3 1.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_4 PF07721.14 EMC91910.1 - 1.6e-09 37.5 10.8 0.0027 18.2 0.2 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC91910.1 - 1.7e-09 37.8 3.8 0.023 14.9 0.1 4.8 2 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EMC91910.1 - 1.1e-08 35.1 5.7 0.28 11.9 0.3 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMC91910.1 - 2.2e-08 33.6 3.5 0.29 11.5 0.1 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMC91910.1 - 1e-07 32.2 12.6 0.02 15.7 2.6 6.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC91910.1 - 5.3e-07 29.3 5.2 0.1 12.7 0.2 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMC91910.1 - 2.7e-06 27.4 2.1 0.21 12.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 EMC91910.1 - 7.6e-06 26.3 0.1 5.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_20 PF14561.6 EMC91910.1 - 1.2e-05 25.5 13.3 0.78 10.1 0.3 5.5 2 1 3 5 5 5 3 Tetratricopeptide repeat AAA_16 PF13191.6 EMC91910.1 - 5.3e-05 23.7 0.5 5.3e-05 23.7 0.5 2.9 3 1 0 3 3 1 1 AAA ATPase domain NACHT PF05729.12 EMC91910.1 - 0.0026 17.7 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_1 PF00515.28 EMC91910.1 - 0.0027 17.5 3.4 14 5.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 EMC91910.1 - 0.0035 17.5 0.0 5.4 7.5 0.0 4.9 4 0 0 4 4 4 1 PPR repeat TPR_16 PF13432.6 EMC91910.1 - 0.0036 17.9 10.6 0.018 15.7 3.5 4.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMC91910.1 - 0.01 15.8 7.1 31 4.9 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TniB PF05621.11 EMC91910.1 - 0.068 12.6 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Alkyl_sulf_dimr PF14863.6 EMC91910.1 - 0.83 10.1 3.4 10 6.6 0.6 3.3 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation YfdX PF10938.8 EMC91910.1 - 0.86 9.5 8.0 0.42 10.5 0.1 3.7 3 2 0 3 3 3 0 YfdX protein DnaJ PF00226.31 EMC91911.1 - 1.1e-15 57.5 1.9 1.5e-15 57.0 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain Jak1_Phl PF17887.1 EMC91911.1 - 0.58 10.1 6.5 1.1 9.2 6.5 1.5 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain AAA_11 PF13086.6 EMC91911.1 - 1.6 8.5 8.4 0.27 11.0 4.6 1.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EMC91912.1 - 1.1e-45 155.5 0.0 1.9e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC91912.1 - 1.3e-25 89.9 0.0 4.1e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMC91912.1 - 1.2e-20 73.4 0.1 4.5e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EMC91912.1 - 0.00022 21.3 0.0 0.00045 20.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EMC91912.1 - 0.034 13.5 0.0 0.034 13.5 0.0 4.1 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Mlh1_C PF16413.5 EMC91913.1 - 8e-95 317.3 0.0 1.3e-94 316.6 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EMC91913.1 - 6e-33 113.0 0.1 1e-32 112.3 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EMC91913.1 - 4.1e-12 46.1 0.0 8.3e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EMC91913.1 - 6.3e-08 33.1 0.0 1.6e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peroxidase_2 PF01328.17 EMC91914.1 - 1.1e-46 159.7 0.0 1.5e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Na_Ca_ex PF01699.24 EMC91915.1 - 2.1e-43 147.9 38.1 2.6e-23 82.7 13.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.12 EMC91915.1 - 0.05 13.8 3.9 0.34 11.1 0.0 3.5 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) RsfS PF02410.15 EMC91917.1 - 9.2e-13 48.5 0.0 1.1e-11 45.0 0.0 2.3 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation DUF924 PF06041.11 EMC91918.1 - 7.4e-36 124.0 0.0 9e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF2306 PF10067.9 EMC91919.1 - 3.7e-15 56.4 12.2 3.7e-15 56.4 12.2 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) GDC-P PF02347.16 EMC91919.1 - 0.11 11.3 0.3 0.15 10.8 0.3 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Glycos_transf_1 PF00534.20 EMC91920.1 - 5.4e-31 107.4 0.0 1.9e-28 99.1 0.0 2.7 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMC91920.1 - 1.9e-15 57.3 0.1 5.1e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EMC91920.1 - 8.3e-14 52.2 0.0 5.6e-13 49.5 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EMC91920.1 - 8.9e-06 26.0 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMC91920.1 - 0.00019 21.9 0.6 0.00064 20.2 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Asp PF00026.23 EMC91921.1 - 1.1e-44 153.1 0.2 1.6e-44 152.6 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EMC91921.1 - 0.00016 22.3 0.3 0.34 11.6 0.2 3.6 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 EMC91921.1 - 0.017 15.4 0.2 0.39 10.9 0.2 2.8 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EMC91921.1 - 0.032 14.8 0.1 14 6.3 0.1 3.2 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease RRM_1 PF00076.22 EMC91922.1 - 1.4e-14 53.6 0.0 2.8e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EMC91922.1 - 0.00015 22.3 4.0 0.00015 22.3 4.0 3.3 2 2 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EMC91922.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Aldedh PF00171.22 EMC91923.1 - 2.2e-187 623.2 1.2 2.5e-187 623.0 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMC91923.1 - 0.15 11.4 0.2 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF3533 PF12051.8 EMC91924.1 - 1.5e-111 373.0 13.3 1.7e-111 372.8 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) VIT1 PF01988.19 EMC91924.1 - 0.065 13.1 0.8 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 VIT family DUF1746 PF08508.10 EMC91924.1 - 0.24 11.8 2.4 0.44 10.9 1.3 2.0 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Oxidored_FMN PF00724.20 EMC91925.1 - 8.3e-37 127.2 0.0 1.4e-36 126.4 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_C37 PF05416.12 EMC91928.1 - 1.1 7.7 5.0 1.3 7.4 5.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase NPR3 PF03666.13 EMC91928.1 - 1.9 7.2 7.8 2.1 7.1 7.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EMC91928.1 - 2.9 6.6 5.0 3.4 6.3 5.0 1.1 1 0 0 1 1 1 0 Presenilin IPK PF03770.16 EMC91930.1 - 8.4e-59 198.8 0.3 3.9e-58 196.6 0.0 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase MSA-2c PF12238.8 EMC91930.1 - 0.061 13.3 1.3 0.14 12.2 1.3 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c tRNA_U5-meth_tr PF05958.11 EMC91931.1 - 1.5e-14 53.8 0.0 1e-13 51.1 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EMC91931.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC91931.1 - 3.9e-06 27.5 0.0 8.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EMC91931.1 - 5.3e-06 26.1 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EMC91931.1 - 0.00017 21.1 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EMC91931.1 - 0.00088 19.9 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC91931.1 - 0.0077 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EMC91931.1 - 0.014 16.1 0.0 0.041 14.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EMC91931.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EMC91931.1 - 0.042 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein AviRa PF11599.8 EMC91931.1 - 0.097 12.1 0.0 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 RRNA methyltransferase AviRa TRM PF02005.16 EMC91931.1 - 0.17 11.0 0.2 0.52 9.4 0.0 1.9 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase MFS_1 PF07690.16 EMC91932.1 - 8.5e-33 113.7 27.3 8.5e-33 113.7 27.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4244 PF14029.6 EMC91932.1 - 3.2 7.3 5.6 8.7 5.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) NAD_binding_9 PF13454.6 EMC91933.1 - 0.1 12.5 0.5 0.22 11.5 0.5 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding zinc_ribbon_15 PF17032.5 EMC91933.1 - 0.86 10.4 9.1 2.2 9.1 7.6 2.1 2 0 0 2 2 2 0 zinc-ribbon family Fungal_trans_2 PF11951.8 EMC91934.1 - 9.9e-13 47.6 1.6 5e-12 45.3 1.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC91934.1 - 8.6e-07 29.0 12.7 1.4e-06 28.3 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syja_N PF02383.18 EMC91935.1 - 2.4e-75 253.8 0.1 4.7e-75 252.9 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain DNA_pol_delta_4 PF04081.13 EMC91936.1 - 1.7e-37 128.7 0.3 1.7e-37 128.7 0.3 2.1 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 DcpS PF05652.12 EMC91937.1 - 4.8e-32 110.9 0.0 7.8e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EMC91937.1 - 4.3e-29 101.3 0.1 6.2e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding ECH_1 PF00378.20 EMC91938.1 - 3.8e-46 157.4 0.0 4e-45 154.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMC91938.1 - 3.6e-24 85.9 1.2 3.1e-21 76.2 0.6 2.7 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EMC91938.1 - 0.016 15.1 0.1 0.043 13.8 0.0 1.6 1 1 1 2 2 2 0 Peptidase family S49 Condensation PF00668.20 EMC91939.1 - 5e-11 41.9 0.3 7.7e-07 28.1 0.5 3.0 2 1 0 2 2 2 2 Condensation domain DUF1890 PF09001.11 EMC91939.1 - 0.15 12.5 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) AMP-binding PF00501.28 EMC91940.1 - 5.1e-76 256.0 0.0 6.6e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC91940.1 - 1.8e-15 57.6 0.2 4e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EMC91940.1 - 0.0017 17.3 0.0 0.0047 15.8 0.0 1.6 2 0 0 2 2 2 1 GH3 auxin-responsive promoter GATase PF00117.28 EMC91942.1 - 2.3e-11 43.8 0.0 3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EMC91942.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GDA1_CD39 PF01150.17 EMC91943.1 - 1.7e-106 356.5 0.0 2.4e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family MmlI PF09448.10 EMC91943.1 - 0.044 14.2 0.0 0.087 13.3 0.0 1.4 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase KGG PF10685.9 EMC91944.1 - 2.2e-22 78.6 12.7 3e-09 36.8 0.1 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif adh_short PF00106.25 EMC91945.1 - 5.5e-53 179.3 0.0 7.3e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC91945.1 - 3.3e-37 128.3 0.0 4e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC91945.1 - 1.2e-13 51.4 0.0 1.7e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMC91945.1 - 0.00016 20.9 0.1 0.00097 18.4 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 EMC91945.1 - 0.057 12.7 1.1 2.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 EMC91945.1 - 0.062 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 EMC91946.1 - 5.7e-25 87.8 0.0 9.5e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC91946.1 - 8.8e-17 62.4 0.0 1.5e-16 61.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC91946.1 - 1.4e-06 28.2 0.0 3.3e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EMC91946.1 - 0.0035 17.2 0.0 0.0078 16.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 EMC91946.1 - 0.04 13.4 0.1 0.075 12.5 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_25 PF13649.6 EMC91946.1 - 0.16 12.7 0.1 0.35 11.6 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Arb1 PF09692.10 EMC91947.1 - 1.2e-126 423.2 0.0 1.4e-126 422.9 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.17 EMC91947.1 - 6.1e-16 58.2 0.0 4.1e-15 55.6 0.0 2.2 2 0 0 2 2 2 1 La domain IPK PF03770.16 EMC91948.1 - 5.5e-53 179.8 0.0 7.3e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase CoA_transf_3 PF02515.17 EMC91949.1 - 5.4e-107 358.1 0.0 6.1e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III CLP1_P PF16575.5 EMC91950.1 - 3.3e-35 121.6 0.0 5.3e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EMC91950.1 - 4.3e-27 94.2 0.1 7.2e-27 93.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EMC91950.1 - 9.3e-27 93.8 0.0 1.5e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_16 PF13191.6 EMC91950.1 - 0.0001 22.7 0.0 0.00029 21.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EMC91950.1 - 0.00015 21.9 0.0 0.43 10.6 0.0 2.7 3 0 0 3 3 3 2 Dynamin family ATP_bind_1 PF03029.17 EMC91950.1 - 0.00041 20.2 0.0 0.0034 17.2 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EMC91950.1 - 0.0029 17.7 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 EMC91950.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_28 PF13521.6 EMC91950.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ion_trans PF00520.31 EMC91951.1 - 0.00046 19.5 18.8 0.00046 19.5 18.8 2.4 2 1 0 2 2 2 1 Ion transport protein PNTB_4TM PF12769.7 EMC91951.1 - 0.043 14.3 0.3 0.13 12.8 0.3 1.8 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch zf-C2H2 PF00096.26 EMC91952.1 - 8.3e-11 41.7 14.2 0.00094 19.5 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC91952.1 - 8.7e-08 32.4 12.4 0.011 16.5 2.0 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMC91952.1 - 2e-06 28.0 11.2 0.0031 17.9 1.8 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 EMC91952.1 - 0.00028 21.2 1.4 2.9 8.4 0.6 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMC91952.1 - 0.00076 19.7 5.8 0.76 10.1 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EMC91952.1 - 0.00092 19.1 4.9 0.0027 17.6 0.6 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 EMC91952.1 - 0.0035 17.9 1.5 0.0035 17.9 1.5 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain zf_ZIC PF18366.1 EMC91952.1 - 1.2 9.3 6.6 2.4 8.4 0.3 3.0 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-RRPl_C4 PF17026.5 EMC91953.1 - 0.0022 18.1 4.1 0.011 15.9 0.3 2.1 1 1 1 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type PI31_Prot_N PF11566.8 EMC91955.1 - 1.6e-54 184.1 0.0 2.1e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EMC91955.1 - 5e-17 62.8 17.1 5e-17 62.8 17.1 2.8 2 1 0 2 2 2 1 PI31 proteasome regulator zf-C3HC4_2 PF13923.6 EMC91958.1 - 2e-11 43.5 10.5 3.7e-11 42.7 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC91958.1 - 3e-09 36.7 8.1 6.6e-09 35.7 8.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMC91958.1 - 1.1e-08 34.9 10.8 2.7e-08 33.7 10.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EMC91958.1 - 1.8e-08 34.1 9.9 3.6e-08 33.1 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC91958.1 - 7.3e-07 29.4 11.0 1.5e-06 28.4 11.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMC91958.1 - 7.6e-07 28.9 7.6 1.5e-06 28.0 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMC91958.1 - 8e-06 25.9 9.3 1.7e-05 24.9 9.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Mob_synth_C PF06463.13 EMC91958.1 - 4.4e-05 23.4 1.2 0.0001 22.3 1.2 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_6 PF14835.6 EMC91958.1 - 4.5e-05 23.2 2.6 7.4e-05 22.5 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EMC91958.1 - 5.6e-05 22.9 7.3 5.6e-05 22.9 7.3 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EMC91958.1 - 0.0002 21.6 7.2 0.0007 19.8 7.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain SAP PF02037.27 EMC91958.1 - 0.00047 19.8 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_10 PF16685.5 EMC91958.1 - 0.00047 20.2 2.8 0.00047 20.2 2.8 2.0 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EMC91958.1 - 0.0054 16.5 7.3 0.055 13.3 7.8 2.2 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain U-box PF04564.15 EMC91958.1 - 0.019 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-P11 PF03854.14 EMC91958.1 - 0.027 14.1 5.0 0.08 12.6 5.1 1.7 1 1 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 EMC91958.1 - 0.038 14.0 1.9 0.12 12.4 1.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 EMC91958.1 - 0.2 11.7 7.1 0.52 10.4 7.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Rubredoxin_2 PF18073.1 EMC91958.1 - 1.1 9.0 5.8 0.15 11.8 1.0 2.0 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn_ribbon_17 PF17120.5 EMC91958.1 - 7.4 6.3 8.8 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Snf7 PF03357.21 EMC91959.1 - 5.3e-21 75.0 19.9 1.1e-20 74.0 19.9 1.4 1 0 0 1 1 1 1 Snf7 SKIP_SNW PF02731.15 EMC91959.1 - 5.1 6.8 12.2 0.41 10.3 4.1 2.3 2 0 0 2 2 2 0 SKIP/SNW domain Atg14 PF10186.9 EMC91959.1 - 5.8 5.9 17.7 0.64 9.0 10.8 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Thioredoxin PF00085.20 EMC91960.1 - 2.7e-28 98.0 0.1 3.1e-28 97.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMC91960.1 - 0.00014 22.3 0.5 0.0018 18.7 0.5 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EMC91960.1 - 0.001 18.8 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EMC91960.1 - 0.0014 18.9 0.0 0.013 15.8 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EMC91960.1 - 0.002 17.5 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EMC91960.1 - 0.029 14.6 0.2 0.04 14.1 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like Disulph_isomer PF06491.11 EMC91960.1 - 0.032 14.3 0.0 0.069 13.2 0.0 1.6 1 1 0 1 1 1 0 Disulphide isomerase Phosducin PF02114.16 EMC91960.1 - 0.1 11.5 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Phosducin KilA-N PF04383.13 EMC91961.1 - 0.0023 17.8 0.0 0.048 13.5 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Rho_GDI PF02115.17 EMC91962.1 - 8e-62 208.5 0.5 9.2e-62 208.3 0.5 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Fumerase_C PF05683.12 EMC91962.1 - 0.0037 16.6 0.3 0.0062 15.9 0.3 1.4 1 1 0 1 1 1 1 Fumarase C-terminus ANAPC4_WD40 PF12894.7 EMC91963.1 - 0.0023 18.2 0.0 0.16 12.3 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EMC91963.1 - 0.084 12.2 0.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 CPSF A subunit region Cupin_8 PF13621.6 EMC91964.1 - 1e-36 127.0 0.0 1.8e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 EMC91964.1 - 2.2e-21 76.7 0.0 3.8e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EMC91964.1 - 5.3e-08 32.7 9.5 0.038 14.0 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Cupin_4 PF08007.12 EMC91964.1 - 7.4e-08 32.2 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_5 PF13854.6 EMC91964.1 - 2.2e-07 30.7 0.2 0.0024 17.8 0.0 3.8 4 1 0 4 4 4 2 Kelch motif DSPc PF00782.20 EMC91965.1 - 2.9e-29 101.6 0.0 1.9e-20 73.0 0.0 2.8 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMC91965.1 - 3.5e-06 26.7 0.0 0.00061 19.4 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EMC91965.1 - 0.021 15.0 0.1 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 EMC91965.1 - 0.063 13.0 1.9 4.5 6.9 0.0 2.9 3 1 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) adh_short PF00106.25 EMC91966.1 - 3.8e-34 117.9 0.0 4.6e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC91966.1 - 5.5e-21 75.2 0.0 7.5e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC91966.1 - 2e-09 37.6 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMC91966.1 - 7.2e-05 22.8 0.3 0.00026 20.9 0.3 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC91966.1 - 0.00012 21.7 0.1 0.00077 19.0 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC91966.1 - 0.014 14.5 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MoeA_N PF03453.17 EMC91967.1 - 5.5e-40 136.7 2.2 8.3e-40 136.1 2.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EMC91967.1 - 9e-31 106.5 0.2 5.6e-26 90.9 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_C PF03454.15 EMC91967.1 - 5.2e-18 65.0 0.0 1.5e-17 63.5 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF1533 PF07550.11 EMC91967.1 - 0.22 11.4 0.0 0.43 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) ATP-synt_C PF00137.21 EMC91968.1 - 6.2e-26 90.5 24.4 1e-14 54.6 10.0 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 EMC91968.1 - 0.05 12.9 2.3 0.083 12.2 0.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 TFIIA_gamma_C PF02751.14 EMC91969.1 - 1.5e-25 89.0 1.2 2.3e-25 88.5 1.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EMC91969.1 - 1.2e-23 82.8 0.1 1.7e-23 82.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain EamA PF00892.20 EMC91970.1 - 0.0029 17.8 14.7 0.03 14.5 14.7 2.0 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EMC91970.1 - 0.011 15.8 2.1 0.014 15.4 2.1 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 Git3 PF11710.8 EMC91971.1 - 1.2e-51 175.4 13.0 1.2e-51 175.4 13.0 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EMC91971.1 - 2.6e-25 88.3 2.7 5.6e-25 87.2 2.7 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EMC91971.1 - 0.00013 21.4 2.0 0.00025 20.5 1.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_C12 PF01088.21 EMC91972.1 - 3.2e-55 187.2 0.0 4e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 GDP_Man_Dehyd PF16363.5 EMC91973.1 - 3.7e-52 177.8 0.0 5.1e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMC91973.1 - 3.8e-48 164.1 0.0 4.9e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMC91973.1 - 6.4e-18 64.7 0.0 9.1e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMC91973.1 - 4.5e-15 55.5 0.0 3.1e-13 49.5 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EMC91973.1 - 1.5e-12 47.2 0.0 2.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EMC91973.1 - 6.4e-10 38.8 0.0 2.2e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMC91973.1 - 2e-07 31.1 0.0 3.9e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EMC91973.1 - 2.2e-05 23.8 0.1 0.0013 17.9 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 EMC91973.1 - 3e-05 23.7 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EMC91973.1 - 0.0027 17.6 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC91973.1 - 0.05 13.2 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Sad1_UNC PF07738.13 EMC91974.1 - 3.8e-08 33.4 0.0 0.0049 16.9 0.0 2.7 2 1 1 3 3 3 2 Sad1 / UNC-like C-terminal DUF4988 PF16378.5 EMC91974.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function HET PF06985.11 EMC91975.1 - 3.3e-15 56.7 0.0 6.1e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP_bind_1 PF03029.17 EMC91976.1 - 3.8e-61 207.0 0.0 5.4e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EMC91976.1 - 0.0036 17.7 0.0 0.02 15.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMC91976.1 - 0.0062 17.1 0.0 0.019 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMC91976.1 - 0.028 14.2 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EMC91976.1 - 0.041 13.5 0.1 3.6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EMC91976.1 - 0.048 13.1 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 EMC91976.1 - 0.056 13.7 0.1 0.2 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMC91976.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMC91976.1 - 0.078 13.1 0.0 0.29 11.2 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase FAD_binding_8 PF08022.12 EMC91977.1 - 7.5e-18 64.6 0.0 1.7e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMC91977.1 - 2.3e-16 60.3 0.0 4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EMC91977.1 - 2.1e-11 44.0 6.1 4.9e-11 42.8 6.1 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 EMC91977.1 - 4.6e-06 27.0 0.1 1.1e-05 25.7 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EMC91977.1 - 0.0002 21.1 0.3 0.0004 20.2 0.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EMC91977.1 - 0.00063 19.5 0.2 0.0019 18.0 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EMC91977.1 - 0.00068 19.0 0.4 0.0014 18.0 0.4 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EMC91977.1 - 0.011 15.3 0.1 0.022 14.3 0.1 1.6 1 0 0 1 1 1 0 EF hand FAD_binding_3 PF01494.19 EMC91980.1 - 4.2e-69 233.4 0.0 5.5e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMC91980.1 - 0.1 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 4HBT PF03061.22 EMC91981.1 - 1.2e-07 32.0 0.0 1.5e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EMC91981.1 - 0.00046 19.6 0.1 0.00066 19.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 EMC91981.1 - 0.00077 19.9 0.0 0.00097 19.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily ADH_N PF08240.12 EMC91982.1 - 8.7e-29 99.6 1.5 1.5e-28 98.9 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC91982.1 - 5.4e-12 45.8 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMC91982.1 - 1e-08 34.9 0.5 6.1e-06 25.9 0.5 2.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AdoHcyase_NAD PF00670.21 EMC91982.1 - 0.015 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_2 PF07992.14 EMC91982.1 - 0.068 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 EMC91983.1 - 1.5e-07 31.9 13.1 2.3e-05 24.8 7.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 EMC91984.1 - 2.8e-13 50.1 3.0 0.0046 17.8 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat NUC153 PF08159.12 EMC91985.1 - 2.7e-18 65.4 13.8 1.3e-14 53.6 1.0 3.5 3 0 0 3 3 3 3 NUC153 domain CBFD_NFYB_HMF PF00808.23 EMC91986.1 - 2.3e-12 47.0 0.5 4e-12 46.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 EMC91986.1 - 0.00048 20.2 0.7 0.0025 17.9 0.1 2.1 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Histone PF00125.24 EMC91986.1 - 0.0055 17.1 0.2 0.0055 17.1 0.2 1.8 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Csc2 PF18320.1 EMC91986.1 - 0.044 12.7 0.4 0.054 12.5 0.4 1.2 1 0 0 1 1 1 0 Csc2 Crispr Cwf_Cwc_15 PF04889.12 EMC91986.1 - 0.15 11.8 15.8 0.21 11.3 15.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 EMC91986.1 - 0.52 9.9 13.9 0.63 9.6 13.9 1.1 1 0 0 1 1 1 0 PPP4R2 RNase_PH PF01138.21 EMC91987.1 - 1.1e-26 93.9 0.0 2.1e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 OTT_1508_deam PF14441.6 EMC91990.1 - 5.2e-19 68.0 6.1 7.6e-19 67.5 6.1 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase YorP PF09629.10 EMC91990.1 - 0.084 13.1 0.3 0.18 12.0 0.3 1.5 1 0 0 1 1 1 0 YorP protein dsrm PF00035.26 EMC91992.1 - 0.00053 20.6 0.0 0.00082 20.0 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Avian_gp85 PF03708.14 EMC91993.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 DNA_Packaging_2 PF11123.8 EMC91994.1 - 0.013 15.7 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 DNA packaging protein FAD-SLDH PF12318.8 EMC91994.1 - 0.047 13.8 0.5 0.078 13.0 0.5 1.4 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase WD40 PF00400.32 EMC91997.1 - 0.00018 22.2 9.1 0.29 12.1 0.0 6.6 7 0 0 7 7 7 1 WD domain, G-beta repeat Lactonase PF10282.9 EMC91997.1 - 0.0013 18.1 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 EMC91997.1 - 0.003 17.4 0.1 4 7.5 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EMC91997.1 - 0.0086 16.3 0.0 0.085 13.2 0.0 2.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMC91997.1 - 0.29 10.1 0.0 4.8 6.0 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cpn10 PF00166.21 EMC91998.1 - 2.4e-31 107.6 0.0 2.7e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit HET PF06985.11 EMC91999.1 - 7e-13 49.2 0.0 8.2e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_76 PF03663.14 EMC92001.1 - 3.3e-105 352.6 21.5 5.6e-105 351.8 21.5 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4462 PF14692.6 EMC92001.1 - 0.037 13.5 0.2 0.07 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) F-box PF00646.33 EMC92003.1 - 1e-08 34.8 0.1 4.1e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EMC92003.1 - 1.1e-07 31.7 0.0 4.3e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 F-box-like Metallophos PF00149.28 EMC92004.1 - 1.2e-37 130.4 0.4 1.9e-37 129.7 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMC92004.1 - 0.003 18.0 0.1 0.0058 17.0 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EMC92004.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RNase_H2_suC PF08615.11 EMC92005.1 - 3.4e-26 92.1 0.0 4.1e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.20 EMC92006.1 - 2.9e-65 220.3 0.0 2.1e-64 217.5 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EMC92006.1 - 9.5e-11 42.3 0.0 1.8e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC92006.1 - 1.6e-10 41.5 0.0 3.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC92006.1 - 1.9e-09 37.6 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC92006.1 - 1.2e-07 31.6 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC92006.1 - 5.9e-06 27.0 0.0 1.2e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EMC92006.1 - 0.0076 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF938 PF06080.12 EMC92006.1 - 0.016 15.0 0.0 0.073 12.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 EMC92006.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EMC92006.1 - 0.05 13.3 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.7 EMC92006.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EMC92008.1 - 2.7e-14 53.6 0.1 6.7e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC92008.1 - 5.1e-14 52.7 0.1 1e-13 51.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC92008.1 - 2.9e-08 33.7 0.0 4.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC92008.1 - 4.6e-08 33.7 0.0 8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC92008.1 - 6.6e-08 32.2 0.0 1.3e-07 31.2 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EMC92008.1 - 3.9e-06 26.7 0.0 6.2e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC92008.1 - 0.0001 21.9 0.1 0.00015 21.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EMC92008.1 - 0.00046 20.0 0.1 0.00091 19.0 0.1 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EMC92008.1 - 0.0019 17.7 0.1 0.0026 17.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EMC92008.1 - 0.0052 16.8 0.0 0.0075 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EMC92008.1 - 0.0068 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EMC92008.1 - 0.018 14.1 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 EMC92008.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 EMC92008.1 - 0.04 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.12 EMC92008.1 - 0.056 12.5 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.17 EMC92008.1 - 0.15 11.5 0.1 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase Metallophos PF00149.28 EMC92009.1 - 5.2e-32 112.0 0.1 3e-22 80.1 0.0 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase Rootletin PF15035.6 EMC92010.1 - 0.033 14.2 3.1 0.054 13.5 3.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3416 PF11896.8 EMC92010.1 - 0.68 10.2 7.0 5.3 7.3 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3416) HAUS6_N PF14661.6 EMC92010.1 - 2.4 7.7 5.7 5.4 6.5 5.6 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MFS_1 PF07690.16 EMC92011.1 - 5.9e-41 140.6 56.2 5.9e-41 140.6 56.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC92011.1 - 1.1e-12 47.2 26.8 1.5e-12 46.8 26.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMC92011.1 - 1.4e-06 27.5 10.6 1.4e-06 27.5 10.6 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter DUF2530 PF10745.9 EMC92011.1 - 0.027 14.7 1.9 0.027 14.7 1.9 5.7 5 1 0 5 5 5 0 Protein of unknown function (DUF2530) Zn_clus PF00172.18 EMC92012.1 - 1.2e-05 25.3 9.5 2.7e-05 24.2 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC92012.1 - 0.03 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 EMC92013.1 - 4.6e-38 131.1 0.0 5.2e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 EMC92014.1 - 3.3e-20 72.6 0.0 4.6e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC92014.1 - 5.1e-14 52.6 0.0 9.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMC92014.1 - 0.00012 22.4 0.3 0.00027 21.2 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EMC92014.1 - 0.00013 22.4 0.0 0.00038 20.9 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMC92014.1 - 0.00028 21.0 0.0 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EMC92014.1 - 0.0032 17.0 0.0 0.0078 15.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EMC92014.1 - 0.0065 16.6 0.1 0.014 15.5 0.0 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EMC92014.1 - 0.026 13.7 0.1 0.051 12.7 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein KR PF08659.10 EMC92014.1 - 0.03 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 KR domain FA_hydroxylase PF04116.13 EMC92017.1 - 2.9e-24 85.9 13.9 5.5e-24 85.0 10.9 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily LysM PF01476.20 EMC92018.1 - 0.0014 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 EMC92018.1 - 0.0017 18.1 0.1 0.0032 17.3 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain zf-C3HC4_3 PF13920.6 EMC92018.1 - 0.088 12.7 9.7 0.075 12.9 6.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC92018.1 - 0.13 12.2 12.2 0.15 12.1 10.2 2.0 2 0 0 2 2 2 0 zinc-RING finger domain TAP_C PF03943.13 EMC92018.1 - 0.17 11.6 1.3 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 TAP C-terminal domain zinc_ribbon_2 PF13240.6 EMC92018.1 - 0.31 10.8 4.2 0.61 9.9 4.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_2 PF13639.6 EMC92018.1 - 1.2 9.6 12.4 2.6 8.4 12.4 1.6 1 1 0 1 1 1 0 Ring finger domain Dus PF01207.17 EMC92019.1 - 8.3e-61 205.8 0.0 1.2e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) p450 PF00067.22 EMC92021.1 - 8.5e-28 97.3 0.0 1.9e-19 69.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 NAD_binding_10 PF13460.6 EMC92022.1 - 3.3e-39 134.7 2.0 4.3e-39 134.3 2.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC92022.1 - 9.6e-11 41.6 0.0 1.3e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EMC92022.1 - 1.5e-09 37.8 0.5 3.3e-09 36.6 0.5 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EMC92022.1 - 0.0002 20.6 0.1 0.00037 19.7 0.0 1.6 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EMC92022.1 - 0.0045 16.0 0.0 0.0057 15.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_transf_4 PF13439.6 EMC92022.1 - 0.0063 16.5 0.0 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 RmlD_sub_bind PF04321.17 EMC92022.1 - 0.012 14.7 0.1 0.017 14.2 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain Glyco_trans_4_4 PF13579.6 EMC92022.1 - 0.013 15.9 0.0 0.042 14.3 0.0 1.8 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Ligase_CoA PF00549.19 EMC92022.1 - 0.028 14.3 0.4 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 CoA-ligase GDP_Man_Dehyd PF16363.5 EMC92022.1 - 0.049 13.0 0.1 0.1 12.0 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_transf_5 PF08323.11 EMC92022.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 Starch synthase catalytic domain DUF1593 PF07632.11 EMC92022.1 - 0.079 12.4 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1593) Peptidase_M24 PF00557.24 EMC92023.1 - 8.5e-52 175.9 0.0 1.2e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EMC92023.1 - 5.3e-24 84.3 0.0 1.5e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Alba PF01918.21 EMC92023.1 - 0.18 11.6 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Alba HSP70 PF00012.20 EMC92026.1 - 2.8e-57 194.2 11.5 6.9e-55 186.4 0.0 2.8 3 1 0 3 3 3 2 Hsp70 protein Interferon PF00143.19 EMC92026.1 - 0.0091 16.2 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Interferon alpha/beta domain MreB_Mbl PF06723.13 EMC92026.1 - 0.11 11.2 0.0 0.3 9.9 0.0 1.7 1 0 0 1 1 1 0 MreB/Mbl protein Flavin_Reduct PF01613.18 EMC92027.1 - 4.5e-17 62.5 0.0 6.3e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_1 PF00561.20 EMC92028.1 - 8.8e-09 35.4 0.0 2.9e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold PAP_central PF04928.17 EMC92029.1 - 1.9e-97 325.2 0.0 2.6e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EMC92029.1 - 1e-54 184.7 0.0 1.5e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EMC92029.1 - 1.1e-08 35.3 0.0 3.2e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EMC92029.1 - 0.023 14.8 0.0 0.24 11.5 0.0 2.2 1 1 1 2 2 2 0 Polymerase beta, Nucleotidyltransferase GFA PF04828.14 EMC92030.1 - 1.2e-25 89.6 0.0 1.7e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.8 EMC92030.1 - 0.031 14.5 0.0 0.054 13.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) RNA_POL_M_15KD PF02150.16 EMC92030.1 - 0.075 12.9 2.8 0.24 11.3 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Tfb5 PF06331.12 EMC92031.1 - 1.2e-18 66.8 3.6 1.3e-18 66.7 3.6 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 adh_short_C2 PF13561.6 EMC92032.1 - 3.5e-44 151.1 0.1 4.3e-44 150.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC92032.1 - 2.2e-36 125.2 0.3 9.5e-36 123.1 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMC92032.1 - 7.7e-07 29.2 0.1 1.2e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 EMC92033.1 - 1.7e-26 93.0 48.3 2.1e-25 89.4 37.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMC92033.1 - 0.00034 19.2 4.1 0.00034 19.2 4.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4202 PF13875.6 EMC92034.1 - 1.1e-76 256.9 1.1 1.2e-76 256.8 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF2102 PF09875.9 EMC92034.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) PilM_2 PF11104.8 EMC92034.1 - 0.082 11.9 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Mannosidase_ig PF17786.1 EMC92035.1 - 5.8e-19 68.5 0.3 1.5e-18 67.2 0.3 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EMC92035.1 - 1.1e-09 39.0 0.2 2.8e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EMC92035.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain DUF1582 PF07621.11 EMC92036.1 - 0.018 15.0 0.3 0.037 14.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) Arf PF00025.21 EMC92038.1 - 1.3e-40 138.7 0.0 4e-26 91.5 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 EMC92038.1 - 3e-14 53.0 0.0 2.5e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EMC92038.1 - 2e-10 40.9 0.0 7.8e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EMC92038.1 - 6.5e-09 35.6 0.0 3.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.12 EMC92038.1 - 2.1e-07 30.6 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMC92038.1 - 4.4e-06 26.2 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EMC92038.1 - 6.4e-05 22.6 0.0 0.0052 16.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMC92038.1 - 7.7e-05 22.7 0.0 0.0002 21.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EMC92038.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 EMC92038.1 - 0.032 13.8 0.0 0.08 12.5 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EMC92038.1 - 0.057 12.8 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ribosomal_S25 PF03297.15 EMC92039.1 - 1e-35 121.9 3.3 1.1e-35 121.8 3.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 EMC92039.1 - 0.0035 17.2 0.1 0.0045 16.8 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EMC92039.1 - 0.01 15.4 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 EMC92039.1 - 0.016 15.0 0.2 0.022 14.5 0.2 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EMC92039.1 - 0.034 14.1 0.1 0.047 13.6 0.1 1.2 1 0 0 1 1 1 0 HTH domain DUF365 PF04033.12 EMC92039.1 - 0.077 13.3 0.3 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Aldo_ket_red PF00248.21 EMC92040.1 - 1.1e-28 100.2 0.0 5e-28 98.1 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Methyltr_RsmB-F PF01189.17 EMC92041.1 - 1e-16 61.2 0.2 2.1e-10 40.6 0.1 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Abhydrolase_6 PF12697.7 EMC92042.1 - 2.1e-18 67.8 0.5 2.6e-18 67.5 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC92042.1 - 5.7e-18 65.1 0.0 7.8e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMC92042.1 - 2.5e-15 56.9 0.1 1.9e-11 44.1 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 EMC92042.1 - 2.6e-06 26.2 0.0 5.1e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_4 PF08386.10 EMC92042.1 - 0.00056 20.0 0.0 0.0014 18.7 0.0 1.7 1 1 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 EMC92042.1 - 0.0014 18.2 0.0 0.022 14.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EMC92042.1 - 0.0021 17.7 0.1 0.0075 15.9 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.14 EMC92042.1 - 0.016 14.0 0.0 0.5 9.0 0.0 2.1 2 0 0 2 2 2 0 Ndr family DLH PF01738.18 EMC92042.1 - 0.083 12.4 0.0 0.48 10.0 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 EMC92042.1 - 0.15 11.7 0.4 0.23 11.1 0.4 1.3 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 EMC92042.1 - 0.15 10.7 0.1 0.26 9.9 0.0 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.7 EMC92042.1 - 0.18 11.5 0.0 2.7 7.7 0.0 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase family NdhN PF11909.8 EMC92042.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N FliD_N PF02465.18 EMC92043.1 - 0.16 12.7 1.7 0.19 12.5 0.2 1.9 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus NDUF_B4 PF07225.12 EMC92044.1 - 0.00012 22.0 0.1 0.00013 21.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) IPI_T4 PF11634.8 EMC92045.1 - 0.088 12.8 0.0 12 6.0 0.0 2.7 3 0 0 3 3 3 0 Nuclease inhibitor from bacteriophage T4 GMC_oxred_N PF00732.19 EMC92046.1 - 2.7e-42 145.1 0.1 2.5e-41 142.0 0.2 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC92046.1 - 3.9e-29 102.0 0.6 9e-29 100.9 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMC92046.1 - 1.2e-08 34.5 0.7 1.6e-07 30.8 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC92046.1 - 1.3e-06 27.9 0.1 8.1e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC92046.1 - 3.5e-06 26.5 0.1 7.2e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC92046.1 - 1.2e-05 25.1 2.9 0.016 14.8 0.5 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC92046.1 - 3.4e-05 24.0 0.4 0.00018 21.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMC92046.1 - 0.00056 19.2 0.5 0.0015 17.9 0.5 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EMC92046.1 - 0.0026 17.2 2.3 0.0039 16.6 2.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC92046.1 - 0.0048 15.7 0.2 0.0048 15.7 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EMC92046.1 - 0.008 15.3 0.1 0.034 13.2 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMC92046.1 - 0.012 14.9 0.0 0.46 9.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC92046.1 - 0.064 13.8 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EMC92046.1 - 0.067 13.6 0.0 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 EMC92046.1 - 0.085 12.2 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 EMC92046.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EMC92046.1 - 0.15 11.3 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMC92046.1 - 0.21 11.2 1.7 0.37 10.3 1.7 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FYVE PF01363.21 EMC92047.1 - 9.6e-15 54.5 11.0 1.3e-14 54.1 10.3 1.5 1 1 1 2 2 2 2 FYVE zinc finger MIF PF01187.18 EMC92049.1 - 5.2e-14 52.5 0.0 6.9e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Sec63 PF02889.16 EMC92051.1 - 3e-15 56.1 0.0 2.1e-14 53.3 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 EMC92051.1 - 1.1e-13 51.1 0.1 2.7e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 EMC92052.1 - 4.1e-22 78.8 0.0 7.5e-21 74.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EMC92052.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EMC92052.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mg_trans_NIPA PF05653.14 EMC92053.1 - 3.7e-102 341.4 15.6 4.4e-102 341.2 15.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EMC92053.1 - 8.5e-05 22.7 6.3 8.5e-05 22.7 6.3 3.4 3 1 0 3 3 3 1 EamA-like transporter family FAD_binding_3 PF01494.19 EMC92057.1 - 1.7e-16 60.4 1.3 2.7e-11 43.3 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EMC92057.1 - 4.5e-09 35.9 0.0 0.00028 20.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC92057.1 - 5.4e-06 25.7 0.5 1e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EMC92057.1 - 1.6e-05 24.5 0.4 0.00015 21.3 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC92057.1 - 2.6e-05 23.1 0.5 0.0029 16.4 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EMC92057.1 - 5.1e-05 23.0 2.1 0.0087 15.7 0.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMC92057.1 - 0.00059 19.2 0.4 0.0036 16.6 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC92057.1 - 0.00094 19.4 0.2 0.0024 18.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC92057.1 - 0.0011 19.5 1.0 1.7 9.3 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMC92057.1 - 0.0012 18.1 0.1 0.0018 17.4 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EMC92057.1 - 0.048 13.0 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EMC92057.1 - 0.051 12.6 0.5 0.17 10.9 0.5 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein DUF4129 PF13559.6 EMC92057.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Thi4 PF01946.17 EMC92057.1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EMC92057.1 - 0.51 9.1 3.5 1.1 8.0 0.5 2.1 1 1 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.16 EMC92058.1 - 2e-29 102.6 26.1 2e-29 102.6 26.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.21 EMC92058.1 - 0.0011 18.0 7.9 0.0017 17.2 7.2 1.7 1 1 0 1 1 1 1 POT family Sars6 PF12133.8 EMC92058.1 - 0.068 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus ISK_Channel PF02060.15 EMC92058.1 - 0.42 10.3 1.3 0.74 9.5 0.1 1.9 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Ribosomal_S7 PF00177.21 EMC92060.1 - 6.7e-36 123.2 2.2 8.6e-36 122.8 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF676 PF05057.14 EMC92061.1 - 0.035 13.6 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EMC92061.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 EMC92061.1 - 0.18 10.9 0.0 0.43 9.7 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Glyco_hydro_3 PF00933.21 EMC92062.1 - 3e-23 82.7 0.0 5.8e-23 81.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EMC92062.1 - 0.00031 20.7 0.0 0.00064 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain CHASE8 PF17152.4 EMC92062.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Periplasmic sensor domain BTB_2 PF02214.22 EMC92064.1 - 3e-07 30.7 0.1 0.0012 19.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain GST_N PF02798.20 EMC92066.1 - 1.6e-08 34.8 0.0 2.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMC92066.1 - 1.5e-06 28.6 0.0 2.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMC92066.1 - 3.2e-05 24.2 0.0 0.00013 22.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMC92066.1 - 0.00014 22.0 0.0 0.00025 21.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMC92066.1 - 0.00027 20.9 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMC92066.1 - 0.0025 18.4 0.0 0.0044 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC92066.1 - 0.027 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PIGA PF08288.12 EMC92067.1 - 3.1e-42 143.1 0.7 3.1e-42 143.1 0.7 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EMC92067.1 - 2.3e-26 92.8 1.3 4.3e-26 91.9 1.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EMC92067.1 - 6.1e-23 81.2 0.0 9.9e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMC92067.1 - 1.6e-20 73.9 0.1 4.2e-20 72.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMC92067.1 - 3.7e-11 43.7 0.0 7.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EMC92067.1 - 0.0015 18.8 0.0 0.0044 17.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EMC92067.1 - 0.0084 16.1 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like DEAD PF00270.29 EMC92068.1 - 1.7e-29 102.8 0.1 5.3e-13 49.1 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC92068.1 - 1.1e-12 48.3 0.1 2.5e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC92068.1 - 2.3e-05 24.4 0.0 0.00011 22.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF515 PF04415.12 EMC92071.1 - 0.0022 16.5 9.1 0.0026 16.2 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF515) CCDC24 PF15669.5 EMC92071.1 - 0.37 10.6 4.4 0.5 10.2 4.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family BES1_N PF05687.13 EMC92071.1 - 1 9.8 5.7 1.4 9.3 5.7 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal RAP1 PF07218.11 EMC92071.1 - 1.3 7.2 6.5 1.4 7.1 6.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PD40 PF07676.12 EMC92073.1 - 5e-05 23.1 1.1 0.056 13.4 0.1 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EMC92073.1 - 5.4e-05 23.4 0.0 1.2 9.5 0.0 4.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EMC92073.1 - 0.00016 19.8 0.0 0.04 11.9 0.0 2.8 3 0 0 3 3 3 2 IKI3 family WD40 PF00400.32 EMC92073.1 - 0.0035 18.1 4.4 6.4 7.8 0.2 5.4 4 1 1 5 5 5 1 WD domain, G-beta repeat BP28CT PF08146.12 EMC92075.1 - 2.5e-36 124.9 1.9 1.9e-35 122.1 0.6 3.4 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EMC92075.1 - 2.6e-22 79.3 1.1 2.6e-22 79.3 1.1 5.3 6 1 0 6 6 6 2 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 EMC92075.1 - 3.5e-06 26.8 6.2 0.56 10.6 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 EMC92075.1 - 3.7 6.0 6.6 3.1 6.3 0.3 3.5 4 0 0 4 4 4 0 Adaptin N terminal region HEAT_EZ PF13513.6 EMC92075.1 - 9.6 6.8 10.2 8 7.1 0.0 5.9 8 0 0 8 8 8 0 HEAT-like repeat NRDE-2 PF08424.10 EMC92076.1 - 1.2e-83 280.9 1.7 6.4e-83 278.5 0.0 2.8 4 0 0 4 4 4 1 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 EMC92076.1 - 0.0022 18.1 0.0 0.026 14.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMC92076.1 - 0.0037 18.0 11.9 0.091 13.6 0.1 7.1 7 2 1 8 8 8 1 Tetratricopeptide repeat DUF3906 PF13046.6 EMC92076.1 - 0.017 15.2 0.7 0.045 13.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) TPR_19 PF14559.6 EMC92076.1 - 0.081 13.4 1.8 2.1 8.9 0.1 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMC92076.1 - 7.9 6.9 5.5 58 4.2 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ELO PF01151.18 EMC92077.1 - 1.4e-75 254.0 5.9 1.8e-75 253.7 5.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family RTX PF02382.15 EMC92077.1 - 0.045 13.4 0.9 0.076 12.7 0.9 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein UPF0270 PF06794.12 EMC92077.1 - 0.19 11.8 0.1 0.34 11.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) adh_short PF00106.25 EMC92078.1 - 1.6e-25 89.7 0.1 3.4e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC92078.1 - 1.6e-12 47.5 0.0 1.2e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC92078.1 - 5.1e-08 33.0 0.1 7.6e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC92078.1 - 0.0023 17.4 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC92078.1 - 0.14 11.5 0.0 0.75 9.1 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EMC92078.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 EMC92081.1 - 1.5e-27 96.3 0.0 2.4e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EMC92081.1 - 2e-25 89.8 0.0 2.9e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EMC92081.1 - 0.0034 17.9 0.0 0.0098 16.5 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EMC92081.1 - 0.026 13.9 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EMC92081.1 - 0.064 13.5 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EMC92081.1 - 0.091 12.3 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EF-hand_1 PF00036.32 EMC92082.1 - 6.4e-27 91.1 12.4 2.6e-07 29.7 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EMC92082.1 - 1.1e-23 83.4 14.1 2.4e-14 53.5 1.5 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EMC92082.1 - 1.4e-20 71.3 6.0 4.6e-05 23.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EMC92082.1 - 4.4e-18 63.9 9.8 2.2e-06 26.9 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EMC92082.1 - 4.1e-13 49.0 11.9 0.00016 21.5 0.8 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EMC92082.1 - 1.1e-06 29.0 0.1 0.0035 17.6 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EMC92082.1 - 6.4e-06 26.1 7.9 0.0028 17.6 0.4 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EMC92082.1 - 0.071 13.3 0.6 0.29 11.4 0.5 2.2 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_9 PF14658.6 EMC92082.1 - 0.077 13.3 0.2 2.4 8.6 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain DUF1770 PF08589.10 EMC92083.1 - 6.4e-34 116.9 0.6 9.1e-34 116.4 0.6 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Sulfotransfer_3 PF13469.6 EMC92085.1 - 3.9e-05 24.1 0.9 0.26 11.6 0.1 3.2 3 1 0 3 3 3 2 Sulfotransferase family SAP18 PF06487.12 EMC92087.1 - 1.3e-36 125.9 0.0 1.5e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 EMC92088.1 - 7.4e-52 175.2 0.0 7.4e-52 175.2 0.0 1.9 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EMC92088.1 - 3.3e-11 42.5 1.6 3.3e-11 42.5 1.6 3.2 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like PLDc_2 PF13091.6 EMC92090.1 - 4.6e-18 65.4 0.0 9.8e-13 48.1 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EMC92090.1 - 0.012 15.8 0.0 4.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif Na_H_Exchanger PF00999.21 EMC92091.1 - 2.1e-61 207.8 15.1 2.4e-61 207.7 15.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-U1 PF06220.12 EMC92095.1 - 2.7e-23 81.4 4.7 3.6e-23 81.0 4.7 1.2 1 0 0 1 1 1 1 U1 zinc finger Actin_micro PF17003.5 EMC92095.1 - 0.074 12.2 0.3 0.074 12.2 0.3 1.0 1 0 0 1 1 1 0 Putative actin-like family Fungal_trans PF04082.18 EMC92099.1 - 3.8e-15 55.7 2.8 5.3e-15 55.2 1.1 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EMC92099.1 - 3.1e-05 24.2 13.0 0.018 15.5 2.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC92099.1 - 0.0036 18.0 7.9 0.59 11.1 2.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger GTP_EFTU PF00009.27 EMC92100.1 - 2.4e-50 170.8 0.0 4.1e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EMC92100.1 - 5.1e-41 139.2 3.6 9.2e-41 138.3 3.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EMC92100.1 - 2.4e-19 69.1 0.0 5.8e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMC92100.1 - 1.1e-07 32.2 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMC92100.1 - 3.5e-05 23.8 0.1 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EMC92100.1 - 6.6e-05 22.6 0.0 0.00028 20.5 0.0 1.9 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 EMC92100.1 - 0.00083 19.4 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1_Xtn PF16897.5 EMC92100.1 - 0.0043 17.1 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RF3_C PF16658.5 EMC92100.1 - 0.011 15.5 0.0 0.038 13.8 0.0 1.9 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EMC92100.1 - 0.016 14.7 0.0 0.033 13.6 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EMC92100.1 - 0.042 14.0 0.0 0.96 9.7 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Snurportin1 PF11538.8 EMC92100.1 - 0.17 12.1 3.4 0.41 10.9 3.4 1.6 1 0 0 1 1 1 0 Snurportin1 HORMA PF02301.18 EMC92101.1 - 2.4e-29 102.4 0.6 2.8e-29 102.2 0.6 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EMC92101.1 - 0.00097 19.1 1.7 0.0044 17.0 1.7 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 AhpC-TSA_2 PF13911.6 EMC92101.1 - 0.0034 17.5 0.0 0.0063 16.6 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF3437 PF11919.8 EMC92101.1 - 0.12 12.3 0.6 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) RICH PF05062.12 EMC92101.1 - 0.13 12.6 3.1 1.7 9.0 0.2 2.4 2 0 0 2 2 2 0 RICH domain Glyco_trans_2_3 PF13632.6 EMC92102.1 - 1.2e-49 168.9 1.5 1.2e-49 168.9 1.5 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMC92102.1 - 1e-06 28.7 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMC92102.1 - 0.00023 21.1 0.1 0.00043 20.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMC92102.1 - 0.0097 15.4 0.0 0.036 13.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Amidohydro_2 PF04909.14 EMC92103.1 - 1.6e-06 28.1 0.5 8.9e-06 25.7 0.2 1.9 1 1 1 2 2 2 2 Amidohydrolase GFA PF04828.14 EMC92105.1 - 4.6e-22 78.2 0.6 6.4e-22 77.7 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 EMC92105.1 - 0.083 13.1 0.0 0.083 13.1 0.0 2.2 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.11 EMC92105.1 - 0.1 12.8 1.9 7.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-PHD-like PF15446.6 EMC92106.1 - 1.5e-66 223.1 15.1 1.5e-66 223.1 15.1 2.0 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 EMC92106.1 - 8.8e-52 176.0 0.0 1.4e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 EMC92106.1 - 3.3e-27 94.1 1.6 7.5e-27 93.0 1.6 1.7 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 EMC92106.1 - 3.8e-18 65.9 0.0 7.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EMC92106.1 - 1.6e-05 24.7 0.9 0.12 12.3 0.2 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 EMC92106.1 - 9.4e-05 21.7 0.2 0.00029 20.1 0.2 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EMC92106.1 - 0.00029 20.9 0.0 0.00059 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 EMC92106.1 - 0.00043 20.1 17.1 0.00051 19.9 8.2 3.1 2 1 1 3 3 3 1 PHD-finger DUF1087 PF06465.13 EMC92106.1 - 0.0054 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) PHD_2 PF13831.6 EMC92106.1 - 4.7 6.9 15.6 0.73 9.4 7.9 3.2 2 1 0 2 2 2 0 PHD-finger SnAC PF14619.6 EMC92106.1 - 7.6 7.2 9.0 0.82 10.3 0.1 3.4 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex SpoU_methylase PF00588.19 EMC92107.1 - 3.8e-24 85.5 0.0 7.1e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EMC92107.1 - 9e-10 38.7 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding HTH_39 PF14090.6 EMC92107.1 - 0.0031 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain GST_N_2 PF13409.6 EMC92108.1 - 4.3e-08 33.3 0.1 7.6e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMC92108.1 - 8.9e-08 32.4 0.1 1.8e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMC92108.1 - 3.2e-05 24.1 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMC92108.1 - 0.00036 20.5 0.0 0.00068 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC92108.1 - 0.024 14.8 0.0 0.054 13.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LMWPc PF01451.21 EMC92110.1 - 7.3e-32 110.7 0.0 8.7e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MFS_1 PF07690.16 EMC92111.1 - 6.2e-44 150.4 21.9 6.4e-41 140.5 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC92111.1 - 6.5e-14 51.6 3.6 6.5e-14 51.6 3.6 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EMC92111.1 - 9.3e-09 34.2 6.1 9.3e-09 34.2 6.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ICL PF00463.21 EMC92112.1 - 2.7e-294 976.5 1.0 3e-294 976.4 1.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EMC92112.1 - 4.9e-11 42.5 0.2 1.2e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.16 EMC92113.1 - 2e-43 148.7 66.4 1.1e-40 139.7 35.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC92113.1 - 2.3e-13 49.8 9.0 2.3e-13 49.8 9.0 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EMC92113.1 - 6e-06 25.8 14.7 0.00057 19.3 6.7 2.5 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EMC92113.1 - 0.016 13.6 16.7 0.056 11.7 3.0 3.7 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4131 PF13567.6 EMC92113.1 - 0.024 14.3 0.4 0.024 14.3 0.4 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF4381 PF14316.6 EMC92113.1 - 0.51 10.6 2.8 3.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TPMT PF05724.11 EMC92114.1 - 6.6e-35 120.8 0.0 2.5e-33 115.6 0.0 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 EMC92114.1 - 1.8e-09 38.1 0.0 3.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC92114.1 - 5.6e-09 36.0 0.0 7.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC92114.1 - 1.8e-07 31.8 0.0 5.3e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC92114.1 - 4.6e-07 30.5 0.0 1.2e-06 29.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC92114.1 - 5.1e-07 29.6 0.0 1.2e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EMC92114.1 - 0.0013 19.0 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TehB PF03848.14 EMC92114.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB AtuA PF07287.11 EMC92116.1 - 1.7e-127 424.9 0.3 2.1e-127 424.7 0.3 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA FAD_binding_4 PF01565.23 EMC92116.1 - 0.041 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HSP70 PF00012.20 EMC92117.1 - 4.9e-11 41.5 0.6 2.1e-09 36.1 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EMC92117.1 - 0.017 14.0 0.1 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Myc_N PF01056.18 EMC92118.1 - 0.063 13.2 0.4 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region PEX11 PF05648.14 EMC92119.1 - 4.3e-13 49.3 0.2 1.8e-12 47.2 0.2 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NmrA PF05368.13 EMC92120.1 - 2.1e-14 53.7 0.0 4.5e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EMC92120.1 - 1.1e-09 38.4 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding YL1 PF05764.13 EMC92121.1 - 0.0088 16.2 5.2 0.015 15.4 5.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein DUF2631 PF10939.8 EMC92121.1 - 0.047 13.5 0.3 1.2 9.0 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) DUF3719 PF12516.8 EMC92121.1 - 0.063 13.0 1.2 0.15 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) DUF1472 PF07339.12 EMC92121.1 - 0.083 13.4 1.0 0.22 12.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1472) Voltage_CLC PF00654.20 EMC92121.1 - 0.24 10.6 3.6 0.51 9.5 0.0 2.3 2 1 0 2 2 2 0 Voltage gated chloride channel DUF883 PF05957.13 EMC92121.1 - 0.35 11.5 3.4 7 7.3 0.0 4.1 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF5345 PF17280.2 EMC92121.1 - 7 6.7 8.8 4.8 7.2 0.4 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5345) AalphaY_MDB PF04611.12 EMC92122.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.0 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Csc2 PF18320.1 EMC92122.1 - 0.13 11.2 0.0 0.14 11.1 0.0 1.0 1 0 0 1 1 1 0 Csc2 Crispr bZIP_1 PF00170.21 EMC92123.1 - 3e-08 33.7 5.7 3e-08 33.7 5.7 2.3 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EMC92123.1 - 0.00017 21.6 5.6 0.00017 21.6 5.6 2.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMC92123.1 - 0.0073 16.8 7.8 0.0073 16.8 7.8 3.1 2 1 1 3 3 3 1 bZIP Maf transcription factor UPF0565 PF10561.9 EMC92123.1 - 0.048 12.9 2.4 0.08 12.1 2.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Peptidase_C98 PF15499.6 EMC92123.1 - 1.3 8.5 4.2 1.7 8.0 4.2 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase BCAS2 PF05700.11 EMC92127.1 - 4e-47 160.6 0.2 4.8e-47 160.3 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) AMPK1_CBM PF16561.5 EMC92128.1 - 3.1e-21 75.4 0.3 5.9e-21 74.5 0.3 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EMC92128.1 - 0.11 12.9 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) RNA_pol_Rpb1_1 PF04997.12 EMC92129.1 - 1.1e-80 271.3 0.0 1.9e-80 270.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EMC92129.1 - 1e-78 264.5 0.0 1.8e-78 263.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMC92129.1 - 2.1e-70 236.2 0.1 3.7e-70 235.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EMC92129.1 - 4.1e-35 121.1 0.0 1e-34 119.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EMC92129.1 - 5.8e-29 100.2 0.1 1.4e-28 99.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FHA PF00498.26 EMC92130.1 - 2.7e-14 53.2 0.0 5.9e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EMC92130.1 - 0.041 14.2 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain F-box-like PF12937.7 EMC92131.1 - 0.06 13.2 1.1 0.11 12.5 0.2 1.9 2 0 0 2 2 2 0 F-box-like FYVE PF01363.21 EMC92131.1 - 0.098 12.8 10.9 0.23 11.6 8.6 2.7 2 1 0 2 2 2 0 FYVE zinc finger IBR PF01485.21 EMC92131.1 - 0.28 11.4 5.5 4.9 7.5 0.3 3.1 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-C2HC5 PF06221.13 EMC92131.1 - 2.8 8.0 11.2 2 8.5 3.2 3.2 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-B_box PF00643.24 EMC92131.1 - 5.4 7.3 8.0 0.72 10.1 0.9 2.6 2 0 0 2 2 2 0 B-box zinc finger Pkinase PF00069.25 EMC92132.1 - 2.7e-25 89.2 0.0 3.2e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92132.1 - 7e-15 55.0 0.0 8.4e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC92132.1 - 0.054 12.8 0.1 0.53 9.5 0.1 2.0 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EMC92132.1 - 0.064 12.0 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Oxysterol_BP PF01237.18 EMC92133.1 - 1.2e-114 383.1 0.0 7.6e-114 380.4 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EMC92133.1 - 1e-35 121.8 0.1 1e-35 121.8 0.1 2.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EMC92133.1 - 5.3e-06 26.9 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF3602 PF12223.8 EMC92134.1 - 2.8e-12 47.1 10.1 6.9e-11 42.6 0.3 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Actin PF00022.19 EMC92135.1 - 6e-125 417.0 0.0 3.8e-124 414.4 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EMC92135.1 - 0.0059 15.5 0.0 2.9 6.6 0.0 2.8 2 1 0 2 2 2 2 MreB/Mbl protein zf-C2H2_4 PF13894.6 EMC92136.1 - 0.02 15.7 2.5 1.3 10.0 0.2 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMC92136.1 - 0.047 14.2 5.0 0.39 11.3 0.2 2.7 2 1 0 2 2 2 0 Zinc finger, C2H2 type Proteasome PF00227.26 EMC92138.1 - 1.8e-49 167.8 0.1 2.7e-49 167.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMC92138.1 - 4.2e-12 45.5 0.2 7.1e-12 44.8 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Amidase_5 PF05382.13 EMC92138.1 - 0.084 12.8 0.0 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase Ribophorin_II PF05817.14 EMC92138.1 - 0.2 10.2 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II DUF2373 PF10180.9 EMC92139.1 - 1.9e-22 78.8 0.5 3.2e-22 78.1 0.5 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Amidase PF01425.21 EMC92140.1 - 1.1e-31 110.4 1.0 1.7e-31 109.7 1.0 1.3 1 0 0 1 1 1 1 Amidase Aft1_HRR PF11787.8 EMC92143.1 - 1.2e-25 90.4 7.2 1.2e-25 90.4 7.2 3.9 4 1 0 4 4 4 1 Aft1 HRR domain Aft1_HRA PF11786.8 EMC92143.1 - 4.4e-21 75.0 10.5 4.4e-21 75.0 10.5 2.7 2 0 0 2 2 2 1 Aft1 HRA domain bZIP_1 PF00170.21 EMC92143.1 - 1.8e-13 50.3 3.4 3e-13 49.7 3.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 EMC92143.1 - 8.5e-11 42.1 9.2 8.5e-11 42.1 9.2 4.3 6 0 0 6 6 6 2 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 EMC92143.1 - 4.3e-06 26.7 5.9 7.4e-06 25.9 5.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMC92143.1 - 0.002 18.6 1.9 0.0048 17.4 1.9 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Nnf1 PF03980.14 EMC92143.1 - 0.2 12.0 3.5 0.55 10.6 3.5 1.8 1 1 0 1 1 1 0 Nnf1 GCP_C_terminal PF04130.13 EMC92145.1 - 7.6e-97 324.5 0.0 1.2e-96 323.8 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EMC92145.1 - 5.9e-81 272.4 0.0 2.3e-80 270.5 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Chitin_synth_1 PF01644.17 EMC92146.1 - 7.4e-74 247.1 0.8 1.1e-73 246.6 0.8 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EMC92146.1 - 8.9e-30 102.5 0.1 1.6e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EMC92146.1 - 8.4e-21 74.2 10.4 3.7e-18 65.5 0.0 3.2 1 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EMC92146.1 - 7.1e-09 35.9 1.5 7.1e-09 35.9 1.5 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 RNA_ligase PF09414.10 EMC92146.1 - 0.025 14.9 0.1 0.046 14.0 0.1 1.5 1 0 0 1 1 1 0 RNA ligase DUF4199 PF13858.6 EMC92146.1 - 3.4 8.0 20.5 0.036 14.5 10.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Chorion_3 PF05387.11 EMC92148.1 - 0.23 11.1 2.6 0.22 11.1 2.6 1.1 1 0 0 1 1 1 0 Chorion family 3 UQ_con PF00179.26 EMC92149.1 - 7.4e-38 129.4 0.0 9.8e-38 129.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMC92149.1 - 0.023 14.4 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B MOSC PF03473.17 EMC92150.1 - 1.2e-27 96.6 0.0 1.7e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EMC92150.1 - 7.9e-16 58.0 0.0 1.3e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain fn3 PF00041.21 EMC92151.1 - 0.064 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain GFA PF04828.14 EMC92151.1 - 0.97 9.8 8.2 0.055 13.8 2.5 1.8 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme L_HMGIC_fpl PF10242.9 EMC92152.1 - 5.6e-05 23.4 5.3 0.0001 22.6 5.3 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein UPF0242 PF06785.11 EMC92152.1 - 0.22 11.6 1.5 0.21 11.6 0.3 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ceramidase_alk PF04734.13 EMC92154.1 - 3.1e-200 666.1 0.0 3.6e-200 665.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EMC92154.1 - 1.1e-58 197.8 0.0 1.9e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal PATR PF12951.7 EMC92154.1 - 0.31 11.2 2.3 11 6.2 0.1 3.4 3 0 0 3 3 3 0 Passenger-associated-transport-repeat Peptidase_S10 PF00450.22 EMC92156.1 - 1.7e-76 258.3 0.0 2.1e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MRP-L20 PF12824.7 EMC92157.1 - 4.6e-54 183.0 9.1 5.9e-54 182.6 9.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 EMC92157.1 - 0.00013 22.0 0.6 0.00027 21.0 0.4 1.6 1 1 0 1 1 1 1 Neugrin HTH_32 PF13565.6 EMC92157.1 - 0.02 15.5 1.5 0.02 15.5 1.5 2.8 2 1 1 3 3 3 0 Homeodomain-like domain MRJP PF03022.16 EMC92158.1 - 1.4e-06 27.9 0.0 1.5e-05 24.5 0.0 2.3 1 1 1 2 2 2 1 Major royal jelly protein SGL PF08450.12 EMC92158.1 - 0.007 16.0 0.7 3.6 7.1 0.0 3.4 2 2 1 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region Con-6 PF10346.9 EMC92159.1 - 1.1e-29 102.2 8.1 7.5e-15 54.7 2.3 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Ketoacyl-synt_C PF02801.22 EMC92160.1 - 0.083 12.9 0.0 0.088 12.8 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Cyt-b5 PF00173.28 EMC92161.1 - 1.8e-19 69.7 0.1 1.8e-19 69.7 0.1 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EMC92161.1 - 6.1e-13 49.3 19.7 6.1e-13 49.3 19.7 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EMC92161.1 - 0.0046 17.2 0.2 0.012 15.8 0.2 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region COX14 PF14880.6 EMC92161.1 - 0.16 11.8 1.8 0.93 9.4 0.1 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly ATP-synt_I PF03899.15 EMC92161.1 - 0.23 11.8 1.7 0.4 11.1 0.2 1.9 2 0 0 2 2 2 0 ATP synthase I chain UbiA PF01040.18 EMC92161.1 - 4.1 6.6 15.0 3 7.0 4.9 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family CPBP PF02517.16 EMC92161.1 - 4.5 7.7 15.4 4.5 7.7 3.7 2.4 1 1 1 2 2 2 0 CPBP intramembrane metalloprotease Tubulin_3 PF14881.6 EMC92164.1 - 1.3e-75 253.0 0.0 1.9e-75 252.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EMC92164.1 - 5.2e-42 142.9 0.0 2.7e-41 140.6 0.0 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EMC92164.1 - 0.0001 22.6 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Mucin PF01456.17 EMC92166.1 - 0.072 13.1 27.1 0.11 12.5 27.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 EMC92166.1 - 1.1 9.4 16.4 1.4 9.1 16.4 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus SOG2 PF10428.9 EMC92166.1 - 6.2 5.9 24.5 7.3 5.7 24.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PSI_8 PF00796.18 EMC92169.1 - 5.5 6.9 7.6 31 4.5 0.3 3.6 3 0 0 3 3 3 0 Photosystem I reaction centre subunit VIII Cyt-b5 PF00173.28 EMC92170.1 - 1.2e-10 41.3 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rhabdo_M1 PF03342.13 EMC92170.1 - 0.053 12.9 0.3 8.9 5.6 0.1 2.1 2 0 0 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Thaumatin PF00314.17 EMC92171.1 - 2.8e-67 226.5 8.7 5e-67 225.7 8.7 1.4 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EMC92171.1 - 0.015 14.6 2.2 0.016 14.5 0.1 1.9 2 0 0 2 2 2 0 Beta-1,3-glucanase Polyketide_cyc2 PF10604.9 EMC92172.1 - 1.2e-06 28.8 0.5 1.5e-06 28.6 0.5 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4520 PF15016.6 EMC92172.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Presenilin PF01080.17 EMC92173.1 - 2.6 6.7 3.3 2.9 6.6 3.3 1.0 1 0 0 1 1 1 0 Presenilin TruD PF01142.18 EMC92174.1 - 2.4e-63 214.4 0.0 2.6e-59 201.1 0.0 3.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Peptidase_S10 PF00450.22 EMC92175.1 - 2.4e-126 422.5 0.1 3.3e-126 422.1 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EMC92175.1 - 6.5e-15 55.8 2.4 1.7e-14 54.4 2.4 1.7 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Cation_efflux PF01545.21 EMC92176.1 - 6.3e-14 52.2 9.4 7.9e-14 51.8 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMC92176.1 - 2.1e-11 43.8 0.6 4.4e-11 42.8 0.6 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF2235 PF09994.9 EMC92178.1 - 3.4e-76 256.3 0.0 5.1e-76 255.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) p450 PF00067.22 EMC92179.1 - 1.7e-76 257.8 0.0 2.2e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adap_comp_sub PF00928.21 EMC92181.1 - 1.1e-16 61.0 0.0 1.6e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMC92181.1 - 7e-08 32.5 0.1 1.2e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EMC92181.1 - 0.016 14.6 0.1 0.038 13.4 0.1 1.6 1 1 0 1 1 1 0 Muniscin C-terminal mu homology domain RPM2 PF08579.11 EMC92181.1 - 0.028 14.8 0.1 0.054 13.9 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 EMC92182.1 - 1.2e-21 76.8 0.6 2.1e-21 76.0 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) ANAPC4 PF12896.7 EMC92184.1 - 2.6e-52 177.3 0.1 3.9e-52 176.7 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EMC92184.1 - 1.8e-14 53.8 0.0 3.9e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain VPR PF00522.18 EMC92184.1 - 0.071 13.2 0.3 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 VPR/VPX protein GAT PF03127.14 EMC92185.1 - 7.9e-16 58.1 0.8 1.3e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 EMC92185.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 VHS domain FAD_binding_3 PF01494.19 EMC92186.1 - 6e-89 298.7 0.0 8e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMC92186.1 - 1e-51 175.3 0.0 1.9e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EMC92186.1 - 0.00057 19.1 0.1 0.00094 18.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMC92186.1 - 0.00083 18.2 0.3 0.0013 17.5 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EMC92186.1 - 0.00087 18.6 0.1 0.0016 17.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC92186.1 - 0.0012 18.1 0.9 0.0026 17.0 0.2 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMC92186.1 - 0.0028 16.8 0.2 0.0074 15.4 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EMC92186.1 - 0.015 14.6 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EMC92186.1 - 0.055 13.7 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Gtr1_RagA PF04670.12 EMC92187.1 - 2.5e-53 180.8 0.0 3.2e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Nbs1_C PF08599.10 EMC92187.1 - 2.1 8.5 4.3 22 5.3 0.3 2.6 3 0 0 3 3 3 0 DNA damage repair protein Nbs1 SDA1 PF05285.12 EMC92188.1 - 5.9e-97 325.2 36.3 7.5e-97 324.9 28.2 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EMC92188.1 - 5.5e-21 74.6 0.2 1.4e-20 73.3 0.2 1.8 1 0 0 1 1 1 1 NUC130/3NT domain ANAPC_CDC26 PF10471.9 EMC92188.1 - 0.49 11.3 5.7 11 6.9 5.6 3.3 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Prefoldin_2 PF01920.20 EMC92189.1 - 8.8e-21 73.9 2.0 1.2e-20 73.4 2.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit KRAP_IP3R_bind PF14722.6 EMC92189.1 - 0.011 15.5 0.3 0.02 14.6 0.2 1.6 1 1 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Seryl_tRNA_N PF02403.22 EMC92189.1 - 0.012 15.9 6.3 2.6 8.3 4.5 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4854 PF16146.5 EMC92189.1 - 0.012 15.9 1.0 0.018 15.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) bZIP_1 PF00170.21 EMC92189.1 - 0.015 15.4 0.3 0.015 15.4 0.3 2.6 2 1 0 2 2 2 0 bZIP transcription factor DUF5082 PF16888.5 EMC92189.1 - 0.016 15.5 5.2 0.024 14.9 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Prefoldin PF02996.17 EMC92189.1 - 0.018 14.9 4.6 0.11 12.4 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit SKA1 PF07160.12 EMC92189.1 - 0.029 14.2 2.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Cluap1 PF10234.9 EMC92189.1 - 0.033 13.6 5.6 0.3 10.4 3.8 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Snapin_Pallidin PF14712.6 EMC92189.1 - 0.034 14.5 5.0 0.96 9.9 0.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin PI3K_P85_iSH2 PF16454.5 EMC92189.1 - 0.042 13.4 8.8 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4337 PF14235.6 EMC92189.1 - 0.046 13.8 3.2 0.046 13.8 2.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FlaC_arch PF05377.11 EMC92189.1 - 0.052 13.9 4.4 0.2 12.1 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 EMC92189.1 - 0.068 13.6 5.2 1.6 9.2 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ubiq_cyt_C_chap PF03981.12 EMC92189.1 - 0.092 12.8 0.2 0.17 11.9 0.0 1.5 2 0 0 2 2 1 0 Ubiquinol-cytochrome C chaperone AKNA PF12443.8 EMC92189.1 - 0.11 13.2 3.8 0.28 11.8 0.1 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor PspA_IM30 PF04012.12 EMC92189.1 - 0.11 12.0 6.8 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 PspA/IM30 family DUF3338 PF11819.8 EMC92189.1 - 0.12 12.3 6.1 2.4 8.2 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) Laminin_II PF06009.12 EMC92189.1 - 0.13 12.3 1.9 0.35 10.9 1.9 1.7 1 1 0 1 1 1 0 Laminin Domain II Rx_N PF18052.1 EMC92189.1 - 0.16 12.3 8.3 2.1 8.7 0.3 2.5 1 1 1 2 2 2 0 Rx N-terminal domain DUF1664 PF07889.12 EMC92189.1 - 0.18 11.8 2.9 1.2 9.1 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 EMC92189.1 - 0.18 12.2 0.4 0.18 12.2 0.4 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) 5_nucleotid PF05761.14 EMC92189.1 - 0.26 10.1 1.7 0.34 9.8 1.7 1.2 1 0 0 1 1 1 0 5' nucleotidase family LPP PF04728.13 EMC92189.1 - 0.31 11.4 2.3 1.2 9.6 0.3 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper V_ATPase_I PF01496.19 EMC92189.1 - 0.61 7.9 2.8 0.81 7.5 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 EMC92189.1 - 0.64 8.6 6.9 2.3 6.7 6.9 1.7 1 1 0 1 1 1 0 Flagellar Assembly Protein A Tektin PF03148.14 EMC92189.1 - 0.8 8.4 11.2 0.1 11.3 0.4 2.0 1 1 1 2 2 2 0 Tektin family zf-CpG_bind_C PF12269.8 EMC92189.1 - 1.3 8.7 8.5 11 5.7 5.6 2.0 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain BST2 PF16716.5 EMC92189.1 - 1.7 9.3 7.8 6.2 7.5 0.1 2.4 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 EMP24_GP25L PF01105.24 EMC92189.1 - 3 7.8 6.4 21 5.0 6.4 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4559 PF15112.6 EMC92189.1 - 5.5 6.6 8.0 5.6 6.5 3.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Atg14 PF10186.9 EMC92189.1 - 6.9 5.6 8.5 1.3e+02 1.5 8.5 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MFS_1 PF07690.16 EMC92190.1 - 2.7e-35 121.9 36.9 2.7e-35 121.9 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC92190.1 - 1.9e-14 53.4 7.9 1.9e-14 53.4 7.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EMC92190.1 - 9.2e-06 25.2 2.8 9.2e-06 25.2 2.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EMC92190.1 - 2 6.6 8.9 4.7 5.4 7.1 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATG27 PF09451.10 EMC92192.1 - 4.4e-95 318.5 0.0 5e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EMC92192.1 - 4.9e-05 23.4 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EMC92192.1 - 0.11 11.5 0.1 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 Mannose-6-phosphate receptor Syja_N PF02383.18 EMC92193.1 - 1.1e-89 301.0 0.0 1.7e-89 300.3 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EMC92193.1 - 9.6e-39 131.7 0.0 2.1e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase Cupin_2 PF07883.11 EMC92194.1 - 8.1e-14 51.1 0.3 1.9e-13 49.9 0.3 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EMC92194.1 - 2.3e-07 30.6 0.0 2.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.8 EMC92194.1 - 0.0022 18.2 0.0 0.0077 16.4 0.0 1.8 1 1 0 1 1 1 1 Mif2/CENP-C like Cupin_3 PF05899.12 EMC92194.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Phage_Gp17 PF17549.2 EMC92194.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Gene Product 17 SNF2_N PF00176.23 EMC92195.1 - 1e-61 208.6 0.0 1.5e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC92195.1 - 5.7e-15 55.6 0.0 1.2e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC92195.1 - 6.8e-10 39.2 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EMC92195.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 EMC92195.1 - 0.0055 15.9 0.0 0.017 14.3 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PDZ_5 PF17817.1 EMC92196.1 - 0.13 12.6 0.1 13 6.1 0.0 2.7 2 0 0 2 2 2 0 PDZ domain PfkB PF00294.24 EMC92199.1 - 5.6e-70 236.0 0.0 6.7e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EMC92199.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DAHP_snth_FXD PF18152.1 EMC92199.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain RSN1_7TM PF02714.15 EMC92200.1 - 1e-82 277.6 30.8 1.8e-82 276.8 30.8 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EMC92200.1 - 2.3e-41 141.2 0.6 2.3e-41 141.2 0.6 3.3 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EMC92200.1 - 1.2e-28 100.5 2.0 9.5e-16 58.5 0.0 3.3 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EMC92200.1 - 2.1e-13 50.2 1.8 6.3e-10 39.1 0.0 3.0 2 1 1 3 3 3 2 Extracellular tail, of 10TM putative phosphate transporter Zip PF02535.22 EMC92200.1 - 0.96 8.6 4.4 4.1 6.5 4.4 2.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAD_binding_3 PF01494.19 EMC92201.1 - 3.9e-09 36.2 1.6 4.8e-05 22.8 0.3 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EMC92201.1 - 0.017 14.3 0.0 0.071 12.3 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC92201.1 - 0.16 12.5 0.1 0.47 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNR_inhib PF08591.10 EMC92202.1 - 6.4e-25 88.5 0.0 1.3e-24 87.5 0.0 1.6 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor HEAT PF02985.22 EMC92203.1 - 3.6e-19 67.2 11.2 1.8e-05 24.6 0.0 10.4 11 0 0 11 11 10 2 HEAT repeat HEAT_EZ PF13513.6 EMC92203.1 - 7.4e-14 51.9 16.9 1e-10 41.9 0.0 8.8 6 3 5 11 11 10 1 HEAT-like repeat HEAT_2 PF13646.6 EMC92203.1 - 8.6e-12 45.3 15.2 0.00084 19.7 0.1 7.7 3 2 4 7 7 7 3 HEAT repeats IBN_N PF03810.19 EMC92203.1 - 3.4e-11 42.9 4.7 1.5e-09 37.6 0.4 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain DRIM PF07539.12 EMC92203.1 - 2.6e-08 32.7 3.1 0.00013 20.5 0.0 4.6 2 1 2 4 4 4 2 Down-regulated in metastasis CLASP_N PF12348.8 EMC92203.1 - 2.6e-07 30.4 1.1 0.18 11.3 0.0 4.9 5 0 0 5 5 5 3 CLASP N terminal Arm PF00514.23 EMC92203.1 - 2.1e-06 27.5 4.1 1 9.5 0.0 5.6 5 1 0 5 5 4 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EMC92203.1 - 4.1e-06 25.6 0.3 0.044 12.3 0.0 3.9 2 1 0 2 2 2 1 Adaptin N terminal region RIX1 PF08167.12 EMC92203.1 - 5.4e-05 23.0 2.7 0.071 12.8 0.1 4.4 2 1 1 3 3 3 2 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 EMC92203.1 - 5.4e-05 23.1 2.4 0.23 11.3 0.0 4.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 EMC92203.1 - 0.00082 19.0 0.9 2.5 7.5 0.0 4.0 3 1 1 4 4 4 1 Tti2 family Cnd1 PF12717.7 EMC92203.1 - 0.00082 19.4 0.4 0.0098 16.0 0.0 3.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 EMC92203.1 - 0.015 15.0 0.1 6.9 6.4 0.0 3.8 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) HEAT_PBS PF03130.16 EMC92203.1 - 0.025 15.2 5.2 10 7.1 0.0 6.1 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat ATP12 PF07542.11 EMC92205.1 - 5.3e-42 142.9 0.0 5.3e-42 142.9 0.0 2.2 3 0 0 3 3 3 1 ATP12 chaperone protein GvpK PF05121.12 EMC92205.1 - 0.062 13.3 1.0 0.084 12.9 0.1 1.7 2 0 0 2 2 2 0 Gas vesicle protein K Fungal_trans PF04082.18 EMC92206.1 - 4.8e-25 88.1 0.0 1.1e-23 83.6 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC92206.1 - 3.9e-07 30.1 7.3 6.9e-07 29.3 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5031 PF16434.5 EMC92206.1 - 0.15 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) DUF1989 PF09347.10 EMC92207.1 - 9.7e-66 220.5 0.0 1.2e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Sulfotransfer_4 PF17784.1 EMC92208.1 - 6.7e-62 209.1 0.0 8.2e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Thioredoxin_8 PF13905.6 EMC92208.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like PHD PF00628.29 EMC92212.1 - 0.00041 20.2 8.4 0.003 17.4 8.4 2.1 1 1 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 EMC92212.1 - 0.016 15.4 3.9 0.03 14.5 3.5 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 EMC92212.1 - 0.11 12.6 0.9 0.21 11.7 0.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 EMC92212.1 - 0.39 11.0 5.1 0.92 9.8 5.1 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_4 PF16866.5 EMC92212.1 - 0.5 10.5 6.2 0.52 10.4 2.8 2.7 1 1 2 3 3 3 0 PHD-finger zf-PHD-like PF15446.6 EMC92212.1 - 0.61 9.7 5.9 0.99 9.0 3.8 2.2 1 1 2 3 3 3 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 EMC92212.1 - 1.6 8.9 5.4 5.2 7.2 5.4 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger Insulin_TMD PF17870.1 EMC92213.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment VSP PF03302.13 EMC92213.1 - 5.3 5.8 8.7 0.45 9.3 3.5 1.6 1 1 0 2 2 2 0 Giardia variant-specific surface protein SBDS_C PF09377.10 EMC92215.1 - 2.3e-44 150.1 0.0 4.6e-44 149.1 0.0 1.5 1 1 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EMC92215.1 - 2.5e-31 107.6 0.1 4.9e-31 106.6 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UBX PF00789.20 EMC92216.1 - 3e-12 46.6 0.0 8.6e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EMC92216.1 - 2e-10 40.3 0.7 4.5e-10 39.2 0.7 1.6 1 0 0 1 1 1 1 UBA-like domain DUF1682 PF07946.14 EMC92216.1 - 0.004 16.4 8.6 0.1 11.8 9.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) BNIP3 PF06553.12 EMC92216.1 - 1.2 8.8 5.2 2.8 7.6 5.2 1.5 1 0 0 1 1 1 0 BNIP3 Presenilin PF01080.17 EMC92216.1 - 2.1 7.0 3.3 3.6 6.3 3.3 1.3 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 EMC92216.1 - 3 7.2 6.7 5.4 6.4 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4449 PF14613.6 EMC92216.1 - 8.1 6.5 7.4 14 5.8 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Pan3_PK PF18101.1 EMC92217.1 - 2.2e-55 186.4 0.1 1.3e-38 132.1 0.0 2.3 2 0 0 2 2 2 2 Pan3 Pseudokinase domain Pkinase PF00069.25 EMC92217.1 - 5.2e-06 26.0 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92217.1 - 0.031 13.6 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3632 PF12311.8 EMC92218.1 - 8.6e-37 127.2 5.0 8.6e-37 127.2 5.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3632) SRP19 PF01922.17 EMC92219.1 - 2.2e-33 115.0 0.0 3e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein Pkinase PF00069.25 EMC92220.1 - 3e-47 161.2 0.0 8e-47 159.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92220.1 - 1.2e-14 54.2 0.0 7e-14 51.7 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase NeA_P2 PF12312.8 EMC92220.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein CPSF73-100_C PF11718.8 EMC92221.1 - 3.4e-80 268.7 0.0 4.7e-80 268.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EMC92221.1 - 1.2e-29 102.8 0.0 2.3e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EMC92221.1 - 7.5e-21 75.0 0.8 1.4e-20 74.2 0.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EMC92221.1 - 3.6e-17 62.4 0.1 7e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EMC92221.1 - 1.3e-12 47.5 0.0 2.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EMC92221.1 - 1.1e-06 28.4 1.0 4.9e-06 26.2 1.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMC92221.1 - 1.7e-05 24.7 0.4 0.0001 22.2 0.2 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EMC92221.1 - 0.0012 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative beta-lactamase-like family PQ-loop PF04193.14 EMC92223.1 - 2.7e-09 36.7 11.8 0.00017 21.3 0.1 3.3 2 1 1 3 3 3 2 PQ loop repeat DUF2070 PF09843.9 EMC92223.1 - 0.0036 15.7 8.0 0.0045 15.4 8.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) TMEM132D_C PF15706.5 EMC92223.1 - 0.39 10.5 9.1 0.43 10.4 1.3 3.2 3 1 1 4 4 4 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Phage_holin_2_3 PF16080.5 EMC92223.1 - 1.2 8.9 11.0 1.5 8.6 0.4 3.5 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Activator-TraM PF11657.8 EMC92224.1 - 0.045 13.6 0.3 0.045 13.6 0.3 1.9 1 1 1 2 2 2 0 Transcriptional activator TraM DUF4484 PF14831.6 EMC92224.1 - 0.55 10.2 8.6 0.021 14.8 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Catalase PF00199.19 EMC92225.1 - 9.1e-05 21.7 0.4 0.017 14.2 0.4 2.1 2 0 0 2 2 2 2 Catalase DUF630 PF04783.12 EMC92225.1 - 0.076 13.2 0.1 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF630) DUF4305 PF14146.6 EMC92226.1 - 0.43 10.8 3.3 1.2 9.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) ALO PF04030.14 EMC92227.1 - 3.9e-82 276.0 1.2 5.7e-82 275.4 1.2 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EMC92227.1 - 2.1e-30 105.3 0.0 3.8e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain His_Phos_1 PF00300.22 EMC92228.1 - 3.4e-09 36.7 0.0 1.7e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) T4-gp15_tss PF16724.5 EMC92228.1 - 0.088 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 T4-like virus Myoviridae tail sheath stabiliser SPX PF03105.19 EMC92228.1 - 1.3 8.9 3.2 1.5 8.7 3.2 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 EMC92228.1 - 5.2 6.2 12.4 7.3 5.7 12.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein GST_C_3 PF14497.6 EMC92230.1 - 2.8e-07 30.6 0.0 4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMC92230.1 - 7.5e-07 29.5 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMC92230.1 - 3.5e-05 24.0 0.0 7.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMC92230.1 - 4.2e-05 23.5 0.0 8.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMC92230.1 - 0.0022 18.6 0.0 0.0035 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC92230.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EMC92230.1 - 0.054 13.3 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain MoaC PF01967.21 EMC92231.1 - 3.4e-51 172.9 0.9 5.6e-51 172.2 0.9 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EMC92231.1 - 2.6e-35 121.2 0.0 2.1e-34 118.2 0.0 2.2 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EMC92231.1 - 1.7e-26 93.6 0.0 3.1e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EMC92231.1 - 1.6e-06 28.5 0.0 3.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMC92231.1 - 0.0044 17.1 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Acetyltransf_10 PF13673.7 EMC92232.1 - 2.7e-07 30.6 0.0 0.0044 17.0 0.0 2.5 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC92232.1 - 0.00016 21.9 0.0 0.00035 20.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 EMC92232.1 - 0.0016 19.1 0.0 0.014 16.1 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC92232.1 - 0.0034 17.8 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMC92232.1 - 0.0079 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DD_K PF12121.8 EMC92234.1 - 0.76 9.9 3.9 4.3 7.5 0.2 2.7 2 0 0 2 2 2 0 Dermaseptin PAC4 PF16093.5 EMC92235.1 - 1.2e-25 89.5 0.1 1.7e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF3739 PF12545.8 EMC92235.1 - 0.055 13.9 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 Filamentous haemagglutinin family outer membrane protein N2227 PF07942.12 EMC92236.1 - 2.3e-88 295.9 0.0 2.8e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Aminotran_3 PF00202.21 EMC92237.1 - 8e-81 271.8 0.0 1.1e-80 271.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DUF4834 PF16118.5 EMC92238.1 - 0.11 13.5 0.2 0.16 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Exo_endo_phos PF03372.23 EMC92239.1 - 2e-07 30.8 0.1 3.6e-07 29.9 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EMC92239.1 - 0.029 14.2 0.0 0.96 9.3 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Asp PF00026.23 EMC92240.1 - 1.3e-69 235.0 13.3 1.6e-69 234.7 13.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMC92240.1 - 1.4e-05 25.4 5.0 0.0012 19.1 3.5 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMC92240.1 - 3e-05 24.6 1.8 0.076 13.7 0.4 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EMC92240.1 - 0.0019 18.0 0.1 0.0091 15.8 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal PDEase_II PF02112.15 EMC92241.1 - 3.3e-49 167.8 0.0 9.7e-44 149.8 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EMC92241.1 - 0.0012 18.4 0.3 0.0036 16.8 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMC92241.1 - 0.19 11.7 3.9 0.42 10.6 3.9 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Metallophos PF00149.28 EMC92242.1 - 5.9e-18 66.1 0.0 1.1e-17 65.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EMC92242.1 - 6.6e-14 52.5 0.1 2.1e-13 50.9 0.1 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EMC92242.1 - 2.2e-13 50.6 1.2 2.2e-13 50.6 1.2 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EMC92242.1 - 7.9e-05 23.1 0.1 0.00027 21.4 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain AA_permease_2 PF13520.6 EMC92243.1 - 1.5e-59 201.9 49.3 1.9e-59 201.6 49.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC92243.1 - 6.3e-22 77.8 42.7 8.6e-22 77.4 42.7 1.1 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.27 EMC92245.1 - 8.4e-43 144.2 7.3 2.8e-15 56.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein K_oxygenase PF13434.6 EMC92246.1 - 8.4e-18 64.6 0.0 3.1e-12 46.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMC92246.1 - 7.3e-09 35.3 0.0 0.0001 21.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC92246.1 - 1e-08 34.8 0.0 0.015 14.6 0.0 3.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC92246.1 - 4.5e-06 26.2 0.0 0.007 15.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EMC92246.1 - 3.9e-05 23.4 5.8 0.0057 16.3 1.0 3.8 2 2 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMC92246.1 - 0.00051 20.1 2.7 0.54 10.2 0.1 3.7 3 2 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EMC92246.1 - 0.0016 17.5 0.0 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMC92246.1 - 0.0018 18.5 0.3 0.07 13.4 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EMC92246.1 - 0.0039 17.2 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EMC92246.1 - 0.0056 15.8 0.1 0.12 11.5 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 EMC92246.1 - 0.012 14.4 0.0 0.78 8.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EMC92246.1 - 0.026 15.1 0.0 9.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC92246.1 - 0.032 13.5 0.0 0.079 12.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EMC92246.1 - 0.2 11.9 0.4 1.2 9.5 0.0 2.4 3 0 0 3 3 3 0 TrkA-N domain Peptidase_S10 PF00450.22 EMC92247.1 - 6.5e-101 338.8 1.4 7.9e-101 338.5 1.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ANAPC10 PF03256.16 EMC92248.1 - 6.1e-41 140.1 0.0 6.6e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 EMC92248.1 - 0.14 12.3 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 PITH domain Alpha-amylase PF00128.24 EMC92249.1 - 7e-23 81.7 0.0 4.9e-20 72.4 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Zn_clus PF00172.18 EMC92251.1 - 1.6e-07 31.3 11.5 2.4e-07 30.7 11.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMC92251.1 - 2e-07 30.2 3.6 3.8e-07 29.3 3.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain A_deaminase PF00962.22 EMC92252.1 - 2.8e-74 250.4 0.0 3.3e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase HMGL-like PF00682.19 EMC92255.1 - 5.4e-78 262.2 0.0 6.1e-77 258.7 0.0 2.0 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 EMC92255.1 - 1.1e-20 73.8 0.4 1.2e-19 70.6 0.4 2.3 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain HSP20 PF00011.21 EMC92257.1 - 4.9e-12 45.9 0.3 6.7e-12 45.5 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EMC92257.1 - 0.006 16.1 0.2 0.041 13.4 0.2 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EMC92257.1 - 0.17 13.0 0.1 0.36 11.9 0.0 1.5 2 0 0 2 2 2 0 CS domain PP2C PF00481.21 EMC92260.1 - 4.1e-37 128.2 0.0 1.7e-30 106.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EMC92260.1 - 9.7e-06 25.4 0.0 2.8e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Epimerase PF01370.21 EMC92261.1 - 1.7e-11 44.1 0.0 3.7e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC92261.1 - 1.7e-08 34.6 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMC92261.1 - 2e-08 33.8 0.0 0.00067 18.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EMC92261.1 - 3.1e-08 33.0 0.0 5.7e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EMC92261.1 - 7.2e-07 29.0 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EMC92261.1 - 8.7e-07 28.6 0.1 2.8e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMC92261.1 - 0.012 14.8 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.25 EMC92261.1 - 0.028 13.9 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 EMC92261.1 - 0.086 11.9 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain PhoD PF09423.10 EMC92262.1 - 6.6e-112 374.0 5.1 8.4e-112 373.7 5.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EMC92262.1 - 1.2e-30 105.8 0.4 3.1e-30 104.5 0.1 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EMC92262.1 - 0.0067 17.0 0.9 0.0067 17.0 0.9 2.9 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain CENP-X PF09415.10 EMC92263.1 - 1.2e-25 89.6 0.3 1.2e-25 89.6 0.3 1.7 2 0 0 2 2 2 1 CENP-S associating Centromere protein X Mis12 PF05859.12 EMC92265.1 - 2.4e-43 147.4 0.8 5e-43 146.4 0.8 1.5 1 0 0 1 1 1 1 Mis12 protein T2SSM PF04612.12 EMC92265.1 - 0.46 10.5 11.1 0.62 10.1 4.6 2.4 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M VWA PF00092.28 EMC92266.1 - 7.6e-06 26.3 0.0 3.1e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EMC92266.1 - 0.00013 22.6 0.0 0.00021 21.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain FTR1 PF03239.14 EMC92269.1 - 1.2e-86 290.7 6.8 1.4e-86 290.4 6.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Acetate_kinase PF00871.17 EMC92269.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Acetokinase family Peptidase_U4 PF03419.13 EMC92269.1 - 2 7.6 8.5 0.032 13.5 0.7 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Cu-oxidase_2 PF07731.14 EMC92270.1 - 1.1e-46 157.9 6.2 4.2e-39 133.4 0.6 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMC92270.1 - 1e-42 144.9 6.5 3.7e-39 133.4 1.1 3.2 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EMC92270.1 - 1.1e-40 139.4 0.7 1.9e-34 119.1 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EMC92270.1 - 0.0006 19.9 0.0 0.76 9.9 0.0 3.4 2 1 1 3 3 3 2 Cupredoxin-like domain OMPdecase PF00215.24 EMC92271.1 - 2e-77 259.8 0.0 2.3e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family IMPa_N_2 PF18650.1 EMC92272.1 - 0.098 11.9 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain PHD PF00628.29 EMC92274.1 - 0.0079 16.1 11.2 0.013 15.4 11.2 1.3 1 0 0 1 1 1 1 PHD-finger LPP20 PF02169.16 EMC92276.1 - 1.1 9.6 4.6 4.7 7.6 4.6 2.1 1 0 0 1 1 1 0 LPP20 lipoprotein DUF29 PF01724.16 EMC92276.1 - 3.2 8.0 9.0 3.5 7.9 6.8 2.2 1 1 0 1 1 1 0 Domain of unknown function DUF29 Glycos_transf_1 PF00534.20 EMC92277.1 - 6.2e-18 64.9 0.0 1.1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMC92277.1 - 2.2e-11 44.3 0.0 4.9e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EMC92277.1 - 1.1e-05 25.7 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Chitin_bind_4 PF00379.23 EMC92277.1 - 0.098 13.2 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Insect cuticle protein Iso_dh PF00180.20 EMC92278.1 - 6.8e-93 311.6 0.0 7.7e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SMBP PF16785.5 EMC92279.1 - 0.15 12.3 0.2 0.15 12.3 0.2 3.0 2 1 0 2 2 2 0 Small metal-binding protein Fez1 PF06818.15 EMC92279.1 - 0.16 12.4 34.2 0.37 11.2 18.9 2.6 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 EMC92279.1 - 0.31 9.9 30.7 0.049 12.5 11.4 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein OmpH PF03938.14 EMC92279.1 - 1.5 9.2 30.7 0.68 10.3 0.7 3.7 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Occludin_ELL PF07303.13 EMC92279.1 - 4.3 8.1 15.6 3.4 8.5 8.3 3.5 3 1 1 4 4 4 0 Occludin homology domain Atg14 PF10186.9 EMC92279.1 - 5.9 5.9 26.6 0.14 11.2 14.1 2.5 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 HJURP_C PF12347.8 EMC92281.1 - 0.0051 16.8 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat CEP63 PF17045.5 EMC92281.1 - 0.0061 16.5 2.1 0.0069 16.3 2.1 1.0 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Dynamitin PF04912.14 EMC92281.1 - 0.011 15.1 1.6 0.013 14.8 1.6 1.1 1 0 0 1 1 1 0 Dynamitin ZapB PF06005.12 EMC92281.1 - 0.033 14.6 0.9 0.55 10.7 0.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB GTP-bdg_M PF16360.5 EMC92281.1 - 0.039 14.5 0.0 0.068 13.8 0.0 1.5 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region HALZ PF02183.18 EMC92281.1 - 0.06 13.6 1.6 0.06 13.6 1.6 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 EMC92281.1 - 0.09 12.6 1.9 4.6 7.1 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Cep57_CLD_2 PF14197.6 EMC92281.1 - 0.41 10.8 3.1 11 6.2 0.1 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TAF4 PF05236.14 EMC92284.1 - 0.00014 21.7 0.0 0.00014 21.7 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Acetyltransf_4 PF13420.7 EMC92286.1 - 6.5e-05 23.1 0.0 0.34 11.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC92286.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Arf PF00025.21 EMC92287.1 - 1.4e-65 220.0 1.6 1.6e-65 219.8 1.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMC92287.1 - 3.4e-12 46.6 0.2 4.8e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EMC92287.1 - 4.4e-12 45.8 1.2 8.5e-07 28.4 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EMC92287.1 - 1e-11 44.7 0.0 1.2e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EMC92287.1 - 4e-09 36.2 0.0 4.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMC92287.1 - 2.3e-08 33.7 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EMC92287.1 - 4.4e-07 30.0 0.0 6.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMC92287.1 - 0.00079 19.0 0.1 0.021 14.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EMC92287.1 - 0.013 15.0 0.5 0.038 13.5 0.5 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF2617 PF10936.8 EMC92287.1 - 0.064 13.3 0.1 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF2617 6PF2K PF01591.18 EMC92287.1 - 0.11 11.7 0.1 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Gelsolin PF00626.22 EMC92288.1 - 1.6e-08 34.3 0.0 0.083 12.8 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat Aldolase_II PF00596.21 EMC92288.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain CN_hydrolase PF00795.22 EMC92289.1 - 9.2e-27 94.0 0.0 1.9e-26 93.0 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Gene66 PF02053.15 EMC92289.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Gene 66 (IR5) protein Cellulase PF00150.18 EMC92290.1 - 8.7e-53 179.6 0.1 1.3e-52 179.0 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EMC92290.1 - 1.3e-11 44.3 12.5 1.3e-11 44.3 12.5 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain CDP-OH_P_transf PF01066.21 EMC92291.1 - 2.8e-11 44.0 0.4 2.8e-11 44.0 0.4 2.2 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase AAA_2 PF07724.14 EMC92292.1 - 3.1e-47 160.9 0.0 1.7e-45 155.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EMC92292.1 - 7e-34 115.9 1.0 7e-34 115.9 1.0 5.1 3 1 2 5 5 5 1 AAA lid domain AAA PF00004.29 EMC92292.1 - 4.8e-27 95.0 0.0 1.9e-14 54.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EMC92292.1 - 1.4e-24 86.0 0.3 4.8e-24 84.2 0.3 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EMC92292.1 - 2.1e-15 56.9 0.3 2e-09 37.6 0.0 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMC92292.1 - 3.3e-13 50.1 0.1 4.4e-05 23.8 0.0 4.5 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EMC92292.1 - 4.1e-13 50.1 5.9 2e-06 28.3 0.1 5.1 3 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 EMC92292.1 - 5.6e-09 35.9 0.0 3.8e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 EMC92292.1 - 2.5e-06 28.1 0.2 0.081 13.5 0.0 3.7 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EMC92292.1 - 4.1e-06 27.0 0.0 0.089 13.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EMC92292.1 - 4.6e-06 26.7 0.0 0.11 12.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EMC92292.1 - 4.9e-06 26.4 0.0 0.12 12.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EMC92292.1 - 5.4e-06 26.0 0.0 0.02 14.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 EMC92292.1 - 1e-05 25.0 0.2 0.13 11.6 0.0 3.5 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EMC92292.1 - 3.9e-05 24.0 0.1 0.5 10.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EMC92292.1 - 8.3e-05 22.9 0.0 0.58 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 EMC92292.1 - 9.1e-05 22.3 0.0 0.67 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EMC92292.1 - 0.00028 20.8 0.0 1.4 8.8 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EMC92292.1 - 0.00028 20.9 0.0 0.4 10.7 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EMC92292.1 - 0.00036 20.5 7.2 0.06 13.2 0.2 4.8 4 1 0 4 4 4 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 EMC92292.1 - 0.00039 19.6 0.2 0.018 14.1 0.0 3.0 3 1 0 3 3 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EMC92292.1 - 0.0004 20.3 0.7 0.4 10.6 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 EMC92292.1 - 0.00044 20.0 0.0 0.51 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EMC92292.1 - 0.001 19.4 0.6 0.24 11.7 0.2 3.5 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EMC92292.1 - 0.0011 18.8 2.7 3.5 7.4 1.0 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 EMC92292.1 - 0.0013 18.4 0.0 0.99 9.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EMC92292.1 - 0.0024 18.4 2.9 0.93 10.0 0.0 3.6 4 0 0 4 4 2 1 ABC transporter Clp_N PF02861.20 EMC92292.1 - 0.0041 17.2 0.5 0.84 9.8 0.0 3.7 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component Roc PF08477.13 EMC92292.1 - 0.005 17.0 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EMC92292.1 - 0.0052 16.1 0.0 0.79 9.0 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin Torsin PF06309.11 EMC92292.1 - 0.0057 16.8 0.0 0.083 13.0 0.0 2.6 3 0 0 3 3 3 1 Torsin NACHT PF05729.12 EMC92292.1 - 0.0057 16.6 0.0 0.37 10.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 EMC92292.1 - 0.0099 15.8 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 1 NTPase SRP54 PF00448.22 EMC92292.1 - 0.011 15.3 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ResIII PF04851.15 EMC92292.1 - 0.013 15.5 0.0 4.7 7.2 0.0 3.8 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 EMC92292.1 - 0.033 14.1 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 EMC92292.1 - 0.048 13.4 0.0 9 6.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 EMC92292.1 - 0.069 12.7 2.6 2.7 7.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EMC92292.1 - 0.12 12.1 0.0 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GAS PF13851.6 EMC92292.1 - 0.14 11.5 17.7 0.43 9.9 17.7 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 EMC92292.1 - 0.27 9.1 8.5 0.47 8.3 8.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 EMC92292.1 - 0.51 10.8 0.0 0.51 10.8 0.0 4.9 4 1 0 4 4 3 0 AAA domain Sigma70_r1_1 PF03979.14 EMC92292.1 - 4.5 7.4 11.8 4.3 7.5 1.4 3.8 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 Amidase PF01425.21 EMC92294.1 - 1.5e-95 320.8 0.0 1.9e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 Amidase His_Phos_2 PF00328.22 EMC92295.1 - 1.4e-19 70.7 0.0 6.9e-19 68.4 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPR_2 PF13041.6 EMC92296.1 - 5.3e-27 93.8 0.7 1.4e-10 41.2 0.1 6.2 6 1 1 7 7 7 4 PPR repeat family PPR_3 PF13812.6 EMC92296.1 - 6.5e-14 51.8 0.0 9.9e-07 28.8 0.0 4.7 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 EMC92296.1 - 5.2e-12 45.2 1.5 3.9e-06 26.8 0.3 5.5 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 EMC92296.1 - 8e-09 35.1 0.0 0.00021 20.9 0.0 5.2 6 0 0 6 6 6 2 PPR repeat SH3_9 PF14604.6 EMC92296.1 - 0.032 14.1 0.1 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain DUF3517 PF12030.8 EMC92296.1 - 0.094 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) PPR_long PF17177.4 EMC92296.1 - 0.1 12.0 0.0 39 3.5 0.0 3.9 5 0 0 5 5 5 0 Pentacotripeptide-repeat region of PRORP SH3_1 PF00018.28 EMC92296.1 - 0.17 11.5 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 SH3 domain Spt20 PF12090.8 EMC92297.1 - 1.6e-34 119.5 0.0 1.6e-34 119.5 0.0 8.2 2 1 1 3 3 3 1 Spt20 family Lactamase_B_4 PF13691.6 EMC92298.1 - 1.1e-22 79.5 0.1 2e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EMC92298.1 - 1.6e-12 47.4 0.1 4.3e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMC92298.1 - 0.019 14.9 0.1 0.72 9.8 0.0 2.5 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily M_domain PF12938.7 EMC92298.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 M domain of GW182 RRM_1 PF00076.22 EMC92299.1 - 5.3e-45 151.1 1.6 1.3e-20 73.0 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EMC92299.1 - 5.5e-20 72.2 0.2 4.1e-19 69.5 0.2 2.6 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 EMC92299.1 - 0.00028 20.9 2.4 0.044 13.8 0.0 3.7 4 0 0 4 4 4 1 RNA binding motif RRM_7 PF16367.5 EMC92299.1 - 0.0055 16.8 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EMC92299.1 - 0.0065 16.1 0.0 0.15 11.7 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC92299.1 - 0.0073 16.1 0.0 0.21 11.4 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EMC92299.1 - 0.021 14.8 0.1 0.46 10.5 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EMC92299.1 - 1.4 9.1 5.9 1.5 9.0 0.2 3.6 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Alpha-mann_mid PF09261.11 EMC92302.1 - 0.039 14.1 0.0 7.2 6.8 0.0 2.2 1 1 1 2 2 2 0 Alpha mannosidase middle domain DUF3328 PF11807.8 EMC92303.1 - 1.5e-34 119.7 0.0 2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CdvA PF18822.1 EMC92305.1 - 0.014 15.2 0.6 0.034 14.0 0.6 1.6 1 0 0 1 1 1 0 CdvA-like coiled-coil domain T3SS_needle_E PF08988.10 EMC92305.1 - 0.087 13.0 1.7 1.5 9.0 0.0 2.8 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DUF2789 PF10982.8 EMC92305.1 - 0.16 12.2 0.7 0.43 10.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) CP12 PF02672.15 EMC92305.1 - 0.28 11.9 1.2 0.55 11.0 0.6 1.7 2 0 0 2 2 2 0 CP12 domain MFS_1 PF07690.16 EMC92306.1 - 5.1e-33 114.5 30.5 5.1e-33 114.5 30.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC92306.1 - 4.8e-16 58.7 4.1 4.8e-16 58.7 4.1 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMC92306.1 - 0.0025 16.3 6.3 0.0025 16.3 6.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_S13 PF00416.22 EMC92307.1 - 4.4e-55 185.5 2.7 5.1e-55 185.3 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EMC92307.1 - 0.0066 15.3 0.0 0.016 14.0 0.0 1.5 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) zf-Mss51 PF13824.6 EMC92309.1 - 7.3e-27 93.2 5.6 1.4e-26 92.4 5.6 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 MMS1_N PF10433.9 EMC92310.1 - 6.9e-102 341.6 0.0 8.8e-102 341.2 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EMC92310.1 - 6.1e-88 295.2 0.0 4.3e-87 292.4 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region EF1G PF00647.19 EMC92311.1 - 1e-44 150.9 0.1 2e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EMC92311.1 - 9.9e-12 45.0 0.0 2.9e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMC92311.1 - 1.3e-11 44.6 2.1 1.8e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMC92311.1 - 7.4e-05 23.1 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMC92311.1 - 0.00014 21.8 0.1 0.0005 20.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMC92311.1 - 0.00053 20.1 0.0 0.0018 18.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RR_TM4-6 PF06459.12 EMC92311.1 - 0.05 13.4 1.6 0.064 13.1 1.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 EMC92311.1 - 0.71 9.5 4.1 1.5 8.5 3.3 1.9 2 0 0 2 2 2 0 FAM176 family Pox_Ag35 PF03286.14 EMC92311.1 - 1.2 8.9 9.1 1.9 8.2 9.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_S9 PF00380.19 EMC92312.1 - 9.1e-42 142.4 0.3 9.1e-42 142.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 HMG_box PF00505.19 EMC92313.1 - 4.9e-15 55.7 2.1 1.1e-14 54.6 2.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMC92313.1 - 0.027 15.0 0.6 0.027 15.0 0.6 1.8 2 0 0 2 2 2 0 HMG-box domain Mtc PF03820.17 EMC92314.1 - 1.5e-125 418.4 0.0 1.9e-125 418.0 0.0 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier PS_Dcarbxylase PF02666.15 EMC92315.1 - 5.2e-77 257.9 0.0 7.9e-76 254.1 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 EMC92315.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit CAP_N PF01213.19 EMC92316.1 - 0.014 14.9 0.9 0.014 14.9 0.9 2.5 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal SAD_SRA PF02182.17 EMC92317.1 - 1.8e-10 40.7 0.0 1.5e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 SAD/SRA domain DUF3884 PF13024.6 EMC92317.1 - 0.086 12.4 0.1 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) Cation_ATPase_C PF00689.21 EMC92318.1 - 1.1e-38 132.7 5.2 1.1e-38 132.7 5.2 3.0 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EMC92318.1 - 1.3e-38 132.3 0.3 1.3e-38 132.3 0.3 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EMC92318.1 - 7e-25 88.6 0.7 6.3e-14 52.8 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMC92318.1 - 1.8e-17 63.2 0.0 3.4e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMC92318.1 - 1.3e-09 37.6 0.0 5.4e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMC92318.1 - 4.6e-05 23.3 0.2 8.9e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMC92318.1 - 0.068 13.6 0.1 0.34 11.3 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EMC92318.1 - 0.19 11.5 4.7 0.35 10.7 0.6 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2231 PF09990.9 EMC92318.1 - 0.72 10.3 7.1 0.06 13.8 1.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) TMEM43 PF07787.12 EMC92318.1 - 4.5 6.6 9.4 0.27 10.6 1.5 2.4 2 0 0 2 2 2 0 Transmembrane protein 43 PAP2 PF01569.21 EMC92319.1 - 5.7e-27 94.1 3.4 9.1e-27 93.5 3.4 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EMC92319.1 - 0.0034 17.1 12.2 0.029 14.0 10.2 2.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EMC92319.1 - 0.022 15.3 0.1 0.022 15.3 0.1 2.2 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RdRP PF05183.12 EMC92320.1 - 6.2e-113 378.5 0.0 8.2e-113 378.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Haem_degrading PF03928.14 EMC92321.1 - 5.6e-37 126.4 0.1 6.7e-37 126.2 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading TCTP PF00838.17 EMC92322.1 - 1.6e-67 227.0 3.3 1.8e-67 226.8 3.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ribosomal_S8 PF00410.19 EMC92323.1 - 2.1e-21 76.2 0.2 3.1e-21 75.6 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Desmo_N PF06771.11 EMC92323.1 - 0.13 12.6 0.1 4.9 7.6 0.1 2.3 1 1 0 1 1 1 0 Viral Desmoplakin N-terminus MtrF PF09472.10 EMC92324.1 - 0.21 11.0 0.5 0.39 10.1 0.5 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) MHYT PF03707.16 EMC92324.1 - 0.33 11.2 4.5 0.4 10.9 0.2 2.5 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Stevor PF17410.2 EMC92324.1 - 1.4 8.4 5.6 0.17 11.4 1.4 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame NAM-associated PF14303.6 EMC92324.1 - 1.8 9.2 4.7 2.8 8.6 4.7 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Gly_transf_sug PF04488.15 EMC92325.1 - 2.6e-11 44.0 0.0 6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif His_Phos_1 PF00300.22 EMC92326.1 - 5.6e-21 75.1 0.0 7.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L22 PF00237.19 EMC92327.1 - 2.2e-42 143.5 0.2 3.7e-42 142.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.17 EMC92328.1 - 7.3e-105 349.1 0.0 9.1e-105 348.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EMC92328.1 - 2.4e-06 27.4 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EMC92328.1 - 0.0055 16.4 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EMC92328.1 - 0.0064 16.3 0.1 0.0094 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ferric_reduct PF01794.19 EMC92330.1 - 2.9e-23 82.4 12.0 9e-23 80.7 12.0 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMC92330.1 - 4.2e-16 59.4 0.0 1.3e-13 51.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMC92330.1 - 6.5e-09 35.8 0.0 7.1e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain DUF4405 PF14358.6 EMC92330.1 - 0.034 14.7 6.0 0.24 12.0 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) SdpI PF13630.6 EMC92330.1 - 0.068 13.3 1.9 0.24 11.6 1.9 1.9 1 0 0 1 1 1 0 SdpI/YhfL protein family NAD_binding_1 PF00175.21 EMC92330.1 - 0.074 13.7 0.1 0.24 12.1 0.1 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Pkinase PF00069.25 EMC92331.1 - 6e-51 173.3 0.0 5.1e-48 163.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92331.1 - 1.5e-29 103.1 0.0 2.7e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC92331.1 - 0.00042 19.7 0.0 0.00064 19.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EMC92331.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EMC92331.1 - 0.054 12.3 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Mem_trans PF03547.18 EMC92333.1 - 6.3e-49 166.4 0.0 1.2e-48 165.4 0.0 1.5 1 1 0 1 1 1 1 Membrane transport protein MscS_TM PF12794.7 EMC92333.1 - 0.07 12.0 7.3 0.42 9.4 0.6 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Fungal_trans PF04082.18 EMC92334.1 - 2.7e-21 75.8 0.0 5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC92334.1 - 1.1e-07 31.8 13.1 2.2e-07 30.9 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1043 PF06295.12 EMC92334.1 - 0.25 11.4 3.3 0.85 9.6 3.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) VIR_N PF15912.5 EMC92334.1 - 7.4 6.1 8.2 17 4.9 8.2 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Pyridoxal_deC PF00282.19 EMC92335.1 - 3.7e-79 266.1 0.0 5e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EMC92335.1 - 3.6e-05 22.9 0.0 5.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Vps39_2 PF10367.9 EMC92336.1 - 3e-06 27.6 0.0 1.6e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EMC92336.1 - 0.0043 17.3 0.1 0.64 10.3 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.6 EMC92336.1 - 0.055 13.8 1.9 3.6 7.9 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMC92336.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat CASP_C PF08172.12 EMC92337.1 - 6e-90 301.0 0.1 6e-90 301.0 0.1 4.2 2 1 3 5 5 3 1 CASP C terminal HALZ PF02183.18 EMC92337.1 - 0.066 13.4 0.2 0.066 13.4 0.2 7.2 6 2 0 6 6 6 0 Homeobox associated leucine zipper DivIC PF04977.15 EMC92337.1 - 0.083 12.7 0.1 0.048 13.4 0.7 7.5 7 2 1 8 8 8 0 Septum formation initiator GAS PF13851.6 EMC92337.1 - 0.15 11.4 58.7 1.6 8.0 0.7 6.4 5 2 1 6 6 6 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EMC92337.1 - 0.25 11.8 0.1 0.25 11.8 0.1 7.0 5 3 0 5 5 5 0 Cell division protein ZapB YabA PF06156.13 EMC92337.1 - 1.2 9.8 0.0 1.2 9.8 0.0 6.4 4 2 2 6 6 6 0 Initiation control protein YabA Filament PF00038.21 EMC92337.1 - 1.4 8.4 47.5 0.43 10.1 4.1 5.4 2 2 3 5 5 5 0 Intermediate filament protein GTP-bdg_M PF16360.5 EMC92337.1 - 1.8 9.2 24.8 4.1 8.1 2.9 5.7 4 1 1 5 5 5 0 GTP-binding GTPase Middle Region Fib_alpha PF08702.10 EMC92337.1 - 3.7 7.7 26.9 0.45 10.7 6.4 4.5 5 0 0 5 5 5 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EMC92337.1 - 3.9 7.5 28.1 0.43 10.6 0.1 5.9 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EMC92337.1 - 3.9 8.1 0.0 3.9 8.1 0.0 8.2 6 2 3 9 9 9 0 SlyX PRKG1_interact PF15898.5 EMC92337.1 - 5.7 7.9 54.9 0.28 12.1 0.6 6.4 5 1 1 6 6 6 0 cGMP-dependent protein kinase interacting domain DUF3455 PF11937.8 EMC92338.1 - 1e-41 142.9 0.1 1.5e-41 142.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EMC92338.1 - 0.26 11.5 4.3 0.24 11.6 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) AMP-binding PF00501.28 EMC92339.1 - 9.7e-60 202.3 0.4 1.5e-22 79.8 0.6 4.5 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 EMC92339.1 - 7.4e-09 36.4 0.0 2.2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain EST1_DNA_bind PF10373.9 EMC92340.1 - 1.4e-44 152.7 0.0 2.4e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EMC92340.1 - 7.1e-17 62.3 0.2 2.1e-16 60.8 0.2 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 FA_hydroxylase PF04116.13 EMC92341.1 - 1.5e-19 70.7 18.0 1.5e-19 70.7 18.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-C2H2 PF00096.26 EMC92342.1 - 0.0069 16.8 11.1 0.43 11.1 0.2 3.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC92342.1 - 1.7 9.7 8.5 3.7 8.6 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger PALP PF00291.25 EMC92343.1 - 5.2e-63 213.2 1.2 5.9e-63 213.0 0.4 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme DUF2000 PF09391.10 EMC92343.1 - 0.1 12.5 0.1 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2000) Sec1 PF00995.23 EMC92345.1 - 2.5e-129 433.2 0.0 2.8e-129 433.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HCV_core PF01542.18 EMC92345.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus core protein BRCT_3 PF18428.1 EMC92345.1 - 0.17 12.0 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF1043 PF06295.12 EMC92345.1 - 0.86 9.6 3.4 1.5 8.9 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) zf_CCCH_4 PF18345.1 EMC92347.1 - 8.4e-07 28.8 2.2 1.6e-06 28.0 2.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EMC92347.1 - 0.00022 20.9 0.7 0.0004 20.1 0.7 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 EMC92347.1 - 0.00058 20.5 0.9 0.0015 19.2 0.1 2.2 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 EMC92347.1 - 0.00092 19.1 1.6 0.0015 18.3 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Angiomotin_C PF12240.8 EMC92347.1 - 0.031 13.8 1.6 0.049 13.2 0.0 2.2 2 0 0 2 2 2 0 Angiomotin C terminal zf-CCCH_2 PF14608.6 EMC92347.1 - 0.079 13.5 0.6 0.14 12.7 0.6 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger TRAPP PF04051.16 EMC92347.1 - 0.083 12.6 0.1 0.89 9.3 0.1 2.2 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component Aldedh PF00171.22 EMC92348.1 - 4.5e-110 368.3 0.8 5.5e-110 368.0 0.8 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sdh5 PF03937.16 EMC92349.1 - 9.3e-15 54.4 0.6 3.4e-14 52.6 0.5 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase DEAD PF00270.29 EMC92354.1 - 1.5e-48 164.9 0.1 3.6e-47 160.4 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC92354.1 - 1.4e-23 83.4 0.0 2.4e-22 79.4 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMC92354.1 - 2e-19 69.6 0.1 3.9e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Golgin_A5 PF09787.9 EMC92354.1 - 0.22 10.9 4.4 0.48 9.8 4.4 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 F-box_4 PF15966.5 EMC92355.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 EMC92355.1 - 0.036 14.0 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 0 F-box-like Glyco_hydro_15 PF00723.21 EMC92356.1 - 1.8e-59 201.7 0.2 2.7e-59 201.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF2475 PF10629.9 EMC92356.1 - 0.41 10.9 3.8 1.7 8.9 1.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) FAD_binding_3 PF01494.19 EMC92358.1 - 1.1e-28 100.5 0.0 1.6e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EMC92358.1 - 1e-06 28.0 0.0 2.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EMC92358.1 - 5.4e-05 23.4 0.9 0.00013 22.2 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMC92358.1 - 0.00021 20.7 1.1 0.1 11.8 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC92358.1 - 0.00028 20.6 0.9 0.0053 16.4 0.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EMC92358.1 - 0.00051 19.4 0.0 0.086 12.1 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EMC92358.1 - 0.0019 17.5 0.4 0.016 14.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC92358.1 - 0.0065 17.0 0.5 0.016 15.7 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC92358.1 - 0.012 14.7 0.4 0.026 13.6 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EMC92358.1 - 0.43 9.6 2.3 6.3 5.7 0.2 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein SH2_2 PF14633.6 EMC92360.1 - 2.4e-82 275.5 1.7 4e-82 274.8 0.0 2.3 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 EMC92360.1 - 1.3e-31 109.4 0.0 5e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 EMC92360.1 - 2.3e-31 108.6 0.8 8.2e-31 106.8 0.8 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EMC92360.1 - 9.8e-30 103.0 0.0 2.3e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 EMC92360.1 - 1.9e-18 66.8 33.2 1.9e-18 66.8 33.2 5.0 5 0 0 5 5 5 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 EMC92360.1 - 1.1e-05 26.3 1.5 1.1e-05 26.3 1.5 3.7 3 1 0 3 3 3 1 HHH domain S1 PF00575.23 EMC92360.1 - 0.0003 21.1 0.1 0.00074 19.8 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 EMC92360.1 - 0.0026 17.8 0.0 0.0066 16.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 EMC92360.1 - 0.0029 17.8 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 EMC92360.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain ATPase_gene1 PF09527.10 EMC92361.1 - 0.028 14.6 0.3 0.062 13.5 0.3 1.5 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter FTHFS PF01268.19 EMC92362.1 - 1.3e-253 842.2 0.0 2.1e-253 841.6 0.0 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EMC92362.1 - 9.5e-67 223.3 0.9 9.5e-67 223.3 0.9 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EMC92362.1 - 6.7e-37 126.3 0.7 1.4e-36 125.3 0.7 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Helicase_C_4 PF13871.6 EMC92362.1 - 0.0076 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue OCD_Mu_crystall PF02423.15 EMC92362.1 - 0.041 12.8 0.1 0.088 11.7 0.1 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family WD40 PF00400.32 EMC92363.1 - 6.4e-26 90.1 0.4 5.9e-06 26.9 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC92363.1 - 2.1e-11 43.9 0.0 0.03 14.6 0.0 5.5 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC92363.1 - 0.023 13.4 0.1 0.29 9.7 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Kelch_1 PF01344.25 EMC92363.1 - 0.083 12.5 0.6 0.74 9.4 0.3 2.2 2 0 0 2 2 2 0 Kelch motif WD40_like PF17005.5 EMC92363.1 - 0.085 12.2 0.0 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain Sugar_tr PF00083.24 EMC92365.1 - 2.8e-87 293.5 16.6 3.4e-87 293.2 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC92365.1 - 1.5e-15 57.0 41.6 4.7e-12 45.5 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_76 PF03663.14 EMC92366.1 - 5.5e-113 378.2 23.2 1.4e-112 376.9 23.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4536 PF15055.6 EMC92367.1 - 1.2e-05 25.4 2.6 2.2e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) Pkinase PF00069.25 EMC92369.1 - 7.8e-67 225.4 0.0 9.6e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92369.1 - 1.1e-31 110.1 0.0 1.5e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMC92369.1 - 0.0069 15.4 0.0 0.025 13.5 0.0 1.9 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EMC92369.1 - 0.049 13.0 0.1 0.1 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMC92369.1 - 0.059 13.3 0.8 0.17 11.8 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family Zn_clus PF00172.18 EMC92370.1 - 3.3e-09 36.7 11.1 4.9e-09 36.2 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 EMC92373.1 - 1e-16 61.2 0.0 3.8e-05 23.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EMC92373.1 - 0.0017 18.5 0.0 0.0054 16.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC92373.1 - 0.16 11.2 0.0 5.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_12 PF13424.6 EMC92374.1 - 3.9e-11 43.1 10.1 0.0027 18.0 0.8 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMC92374.1 - 0.00042 20.2 12.2 0.028 14.5 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EMC92374.1 - 0.0023 17.7 0.6 0.0023 17.7 0.6 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMC92374.1 - 0.0039 17.1 0.4 3.7 7.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMC92374.1 - 0.041 14.1 5.3 10 6.6 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMC92374.1 - 0.044 14.6 11.6 8.1 7.6 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMC92374.1 - 0.045 13.6 7.5 1.2 9.0 0.6 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EMC92374.1 - 0.072 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 SRAP PF02586.14 EMC92375.1 - 1.1e-78 263.8 0.0 1.8e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) G_glu_transpept PF01019.21 EMC92376.1 - 3.2e-141 471.6 0.0 3.6e-141 471.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glyco_transf_4 PF13439.6 EMC92376.1 - 0.0012 18.9 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 RRM_1 PF00076.22 EMC92377.1 - 1.5e-48 162.5 1.5 1.5e-15 56.8 0.4 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC92377.1 - 4.3e-17 61.7 0.1 1.1e-12 47.6 0.0 3.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EMC92377.1 - 3.2e-07 30.3 0.0 0.38 10.8 0.0 4.0 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EMC92377.1 - 4.2e-05 23.5 0.2 3.2 7.8 0.1 4.4 4 0 0 4 4 4 2 RNA binding motif NRDE-2 PF08424.10 EMC92377.1 - 0.00031 20.0 2.5 0.0028 16.9 0.4 3.0 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EMC92377.1 - 0.00036 21.1 4.9 5.8 8.0 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Ribosomal_L22 PF00237.19 EMC92378.1 - 1.5e-24 86.2 0.0 6.9e-24 84.1 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e Hydrolase PF00702.26 EMC92379.1 - 2.5e-09 37.8 0.0 7.7e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMC92379.1 - 4.8e-07 30.0 0.2 5.4e-05 23.4 0.2 2.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC92379.1 - 1.5e-06 28.2 0.1 2.4e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like ORMDL PF04061.14 EMC92380.1 - 1.6e-58 196.3 5.0 1.9e-58 196.1 5.0 1.0 1 0 0 1 1 1 1 ORMDL family DUF2208 PF09973.9 EMC92380.1 - 0.025 14.2 0.7 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) RRM_1 PF00076.22 EMC92381.1 - 1.8e-08 34.1 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trypan_PARP PF05887.11 EMC92381.1 - 6.5e-08 32.6 7.2 6.5e-08 32.6 7.2 1.9 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) zf-CCHC PF00098.23 EMC92381.1 - 2.3e-05 24.3 10.9 0.007 16.4 2.5 2.3 2 0 0 2 2 2 2 Zinc knuckle TonB_N PF16031.5 EMC92381.1 - 0.00022 21.7 9.9 0.00076 20.0 9.9 1.9 1 0 0 1 1 1 1 TonB polyproline region zf-CCHC_5 PF14787.6 EMC92381.1 - 0.11 12.3 5.0 2.8 7.7 0.3 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger HypA PF01155.19 EMC92381.1 - 0.21 11.6 0.3 0.76 9.8 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_3 PF13917.6 EMC92381.1 - 0.55 10.2 5.4 0.73 9.9 0.5 2.4 1 1 1 2 2 2 0 Zinc knuckle CN_hydrolase PF00795.22 EMC92382.1 - 1.1e-45 156.0 0.0 1.3e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NDUFA12 PF05071.16 EMC92383.1 - 5.1e-10 40.1 7.4 1.5e-09 38.5 7.4 2.0 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ArsA_ATPase PF02374.15 EMC92384.1 - 2.1e-106 355.5 0.0 2.4e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EMC92384.1 - 1.7e-14 54.1 0.2 1.8e-13 50.8 0.0 2.4 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 EMC92384.1 - 4.5e-13 49.4 0.0 1.1e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EMC92384.1 - 3e-06 26.9 0.1 6.1e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EMC92384.1 - 3.7e-06 26.7 0.1 0.00036 20.2 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ParA PF10609.9 EMC92384.1 - 6.1e-06 25.9 0.7 5.5e-05 22.7 0.2 2.6 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EMC92384.1 - 0.00025 20.6 0.1 0.0013 18.2 0.0 2.0 2 1 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EMC92384.1 - 0.0019 17.8 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EMC92384.1 - 0.0043 16.3 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.16 EMC92384.1 - 0.0082 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein PIF1 PF05970.14 EMC92384.1 - 0.079 12.1 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase NB-ARC PF00931.22 EMC92384.1 - 0.13 11.4 0.0 0.32 10.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Matrilin_ccoil PF10393.9 EMC92384.1 - 0.13 12.1 0.2 12 5.9 0.0 2.6 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Med8 PF10232.9 EMC92384.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 IstB_IS21 PF01695.17 EMC92384.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MRC1 PF09444.10 EMC92385.1 - 3.7e-22 79.4 19.6 3.7e-22 79.4 19.6 7.5 7 2 3 10 10 10 1 MRC1-like domain PPR_2 PF13041.6 EMC92386.1 - 3.6e-08 33.5 0.0 9.3e-05 22.5 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 EMC92386.1 - 0.0048 16.9 0.0 6.7 6.9 0.0 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 EMC92386.1 - 0.19 12.0 0.0 1.8 9.0 0.0 2.7 3 0 0 3 3 3 0 PPR repeat MFS_MOT1 PF16983.5 EMC92387.1 - 5.6e-62 207.0 35.5 8.2e-33 113.1 9.3 3.0 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily DUF2104 PF09877.9 EMC92387.1 - 0.0052 17.0 0.6 0.022 15.0 0.6 2.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2104) CNPase PF05881.12 EMC92388.1 - 0.078 12.5 0.1 0.09 12.3 0.1 1.1 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) DUF4227 PF14004.6 EMC92388.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DUF1365 PF07103.11 EMC92389.1 - 2e-65 220.8 0.1 3e-65 220.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MFS_1 PF07690.16 EMC92391.1 - 5e-35 121.0 42.9 5e-35 121.0 42.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TAF8_C PF10406.9 EMC92393.1 - 1.9e-20 73.1 4.2 3.3e-20 72.4 2.7 2.2 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EMC92393.1 - 2.8e-08 33.7 0.0 5.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated adh_short_C2 PF13561.6 EMC92395.1 - 1.6e-51 175.1 1.0 1.9e-51 174.9 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC92395.1 - 1.7e-38 132.1 0.7 1.9e-38 131.9 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC92395.1 - 7e-14 52.1 0.4 1.3e-13 51.3 0.4 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EMC92395.1 - 0.024 14.9 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EMC92395.1 - 0.085 12.3 0.0 0.24 10.8 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NPAT_C PF15712.5 EMC92395.1 - 0.089 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 NPAT C terminus DHquinase_II PF01220.19 EMC92395.1 - 0.13 11.9 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Dehydroquinase class II UTP15_C PF09384.10 EMC92396.1 - 6.5e-46 155.7 0.1 9.7e-46 155.1 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EMC92396.1 - 2e-11 44.2 12.8 0.0044 17.8 0.3 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC92396.1 - 2.6e-05 24.5 0.6 0.97 9.8 0.0 4.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain adh_short PF00106.25 EMC92397.1 - 1.3e-35 122.6 0.0 1.7e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC92397.1 - 2.2e-21 76.5 0.0 2.6e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC92397.1 - 2e-06 27.9 0.0 3.1e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC92397.1 - 5.7e-05 22.7 0.0 0.00035 20.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMC92397.1 - 0.00071 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMC92397.1 - 0.0048 16.8 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 EMC92397.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 EMC92397.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.16 EMC92398.1 - 3.2e-43 148.0 40.4 3.2e-43 148.0 40.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4017 PF13209.6 EMC92398.1 - 1.1 9.2 7.8 0.16 11.9 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) Opy2 PF09463.10 EMC92399.1 - 1.1e-08 35.2 22.8 1.9e-08 34.5 22.8 1.4 1 0 0 1 1 1 1 Opy2 protein MAP17 PF15807.5 EMC92399.1 - 0.00068 19.9 0.1 0.0016 18.7 0.1 1.5 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Syndecan PF01034.20 EMC92399.1 - 0.045 13.7 0.2 0.08 12.9 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain MGC-24 PF05283.11 EMC92399.1 - 0.052 14.0 0.0 0.052 14.0 0.0 4.1 2 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 EMC92399.1 - 0.11 13.4 0.0 0.23 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 EMC92399.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2347 PF09804.9 EMC92400.1 - 3.3e-84 282.8 0.0 5e-84 282.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EMC92400.1 - 4.4e-31 108.6 9.7 1.9e-18 67.3 1.8 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4484) SPA PF08616.10 EMC92400.1 - 5.6e-05 23.1 0.0 9.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis T4SS_TraI PF16932.5 EMC92400.1 - 0.06 12.5 0.1 0.097 11.8 0.1 1.3 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer Aminotran_1_2 PF00155.21 EMC92401.1 - 2.2e-14 53.4 0.0 4e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EMC92401.1 - 0.13 11.0 0.0 1.6 7.4 0.0 2.2 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.7 EMC92403.1 - 1e-91 306.6 21.7 4e-83 278.5 9.6 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EMC92403.1 - 2.6e-09 36.6 4.3 0.00085 19.0 0.1 3.6 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase NosD PF05048.13 EMC92403.1 - 0.00016 21.0 4.7 0.00016 21.0 4.7 2.6 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Period_C PF12114.8 EMC92403.1 - 0.27 10.8 1.0 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DEAD PF00270.29 EMC92404.1 - 6.9e-48 162.7 0.0 1.1e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC92404.1 - 8.8e-28 96.9 1.1 2.1e-27 95.6 0.3 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EMC92404.1 - 4.9e-05 22.3 2.7 0.00021 20.2 0.2 2.7 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Glyoxalase PF00903.25 EMC92404.1 - 0.045 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AAA_22 PF13401.6 EMC92404.1 - 0.27 11.5 1.3 1.3 9.3 0.1 2.5 3 0 0 3 3 3 0 AAA domain FAD_binding_4 PF01565.23 EMC92405.1 - 3.4e-25 88.4 0.0 7e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 EMC92405.1 - 2.3e-13 50.3 0.0 5.5e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain 4HBT_3 PF13622.6 EMC92406.1 - 3.1e-86 289.7 0.7 4.1e-86 289.3 0.7 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMC92406.1 - 1.8e-26 92.6 0.0 2e-12 47.1 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Stomoxyn PF11585.8 EMC92408.1 - 8.2 6.5 18.5 4.7 7.3 1.1 3.6 3 0 0 3 3 3 0 Insect antimicrobial peptide, stomoxyn LSM PF01423.22 EMC92409.1 - 2.7e-19 68.6 0.5 4.4e-19 67.9 0.5 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMC92409.1 - 0.03 14.5 0.0 0.043 14.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Zn_clus PF00172.18 EMC92410.1 - 0.55 10.4 12.8 1.8 8.8 12.8 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin_micro PF17003.5 EMC92412.1 - 0.086 12.0 1.8 0.12 11.5 1.8 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2 PF00096.26 EMC92412.1 - 6.9 7.3 12.7 0.12 12.8 3.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC92412.1 - 9 7.4 7.8 3.2 8.8 3.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Choline_kinase PF01633.20 EMC92414.1 - 2.9e-60 203.5 0.0 4.4e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EMC92414.1 - 6.9e-16 57.7 0.0 1.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EMC92414.1 - 1.1e-06 28.7 3.0 1.1e-06 28.7 3.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family GIDA_assoc PF13932.6 EMC92414.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 GidA associated domain DUF5622 PF18533.1 EMC92414.1 - 0.12 12.5 0.2 0.33 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5622) MFS_1 PF07690.16 EMC92415.1 - 1.8e-33 115.9 73.4 4.9e-33 114.5 47.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC92415.1 - 7.9e-12 44.8 18.5 7.9e-12 44.8 18.5 2.8 1 1 0 2 2 2 1 Sugar (and other) transporter DUF3185 PF11381.8 EMC92415.1 - 1.6 8.8 9.7 2.3 8.3 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Abhydrolase_3 PF07859.13 EMC92416.1 - 3.4e-34 118.5 0.0 5.2e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMC92416.1 - 0.00039 19.4 0.0 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 EMC92416.1 - 0.0053 16.3 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 EMC92416.1 - 0.023 14.2 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pox_T4_N PF04491.12 EMC92417.1 - 0.064 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus AIM3 PF17096.5 EMC92418.1 - 0.0037 18.2 2.5 0.0037 18.2 2.5 4.4 5 0 0 5 5 5 1 Altered inheritance of mitochondria protein 3 DUF1737 PF08410.10 EMC92418.1 - 0.19 11.6 0.1 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) Catalase PF00199.19 EMC92419.1 - 2.7e-152 507.3 0.1 5.6e-152 506.3 0.0 1.5 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.12 EMC92419.1 - 6.3e-15 55.1 0.1 1.5e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Phage_holin_3_6 PF07332.11 EMC92421.1 - 0.027 14.5 2.2 0.048 13.7 2.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TrbC PF04956.13 EMC92421.1 - 0.06 13.6 2.2 3 8.1 0.4 2.3 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF1614 PF07758.11 EMC92421.1 - 0.074 13.1 0.2 0.074 13.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) COesterase PF00135.28 EMC92424.1 - 5e-55 187.3 0.0 7.1e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC92424.1 - 8.9e-05 22.4 0.0 0.13 12.1 0.0 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold Pro_isomerase PF00160.21 EMC92425.1 - 1.9e-46 158.2 0.1 2.9e-46 157.6 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EMC92425.1 - 2.7e-07 30.2 7.6 0.00085 19.3 0.9 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMC92425.1 - 0.00015 21.4 10.8 0.004 16.9 0.6 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMC92425.1 - 0.00021 21.8 5.8 0.0016 19.0 2.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMC92425.1 - 0.0052 17.1 0.4 0.57 10.5 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMC92425.1 - 0.023 15.3 0.7 0.67 10.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMC92425.1 - 0.024 15.4 2.3 0.27 12.2 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EMC92425.1 - 0.031 14.3 0.8 0.077 13.0 0.3 1.8 1 1 1 2 2 2 0 Putative TPR-like repeat TPR_8 PF13181.6 EMC92425.1 - 0.032 14.4 2.6 0.035 14.3 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EMC92425.1 - 0.73 9.9 5.1 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain RasGAP PF00616.19 EMC92427.1 - 9.5e-31 107.1 0.1 2.7e-19 69.7 0.0 3.1 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EMC92427.1 - 7.7e-05 22.9 0.0 0.0016 18.7 0.0 2.8 2 1 0 2 2 2 1 C2 domain SmaI PF17411.2 EMC92427.1 - 0.042 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease Abhydrolase_6 PF12697.7 EMC92428.1 - 2.8e-14 54.3 0.3 3.8e-14 53.8 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC92428.1 - 0.00049 19.4 0.0 0.0014 18.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMC92428.1 - 0.00069 19.3 0.3 0.0024 17.6 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC92428.1 - 0.023 14.2 0.0 5.6 6.4 0.3 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.14 EMC92428.1 - 0.057 12.1 0.1 0.095 11.4 0.1 1.3 1 0 0 1 1 1 0 Ndr family Med1 PF10744.9 EMC92429.1 - 1.1e-61 209.2 0.0 1.4e-61 208.8 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 SPX PF03105.19 EMC92430.1 - 0.033 14.1 2.6 0.04 13.8 2.6 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EMC92430.1 - 0.041 12.7 0.5 0.045 12.6 0.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pex14_N PF04695.13 EMC92430.1 - 1.2 9.8 6.3 16 6.1 4.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.11 EMC92430.1 - 1.9 6.5 11.9 2.8 5.9 11.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Amidase PF01425.21 EMC92431.1 - 1.8e-91 307.4 0.0 2.3e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 Amidase RRM_1 PF00076.22 EMC92433.1 - 4.9e-24 83.9 0.1 4.4e-13 48.8 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC92433.1 - 8.5e-05 22.6 0.0 0.14 12.3 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EMC92433.1 - 0.0024 17.8 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RNA12 PF10443.9 EMC92433.1 - 0.12 11.1 2.2 0.18 10.5 2.2 1.2 1 0 0 1 1 1 0 RNA12 protein DUF4569 PF15133.6 EMC92433.1 - 1.7 8.3 5.5 2.4 7.8 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) HSP90 PF00183.18 EMC92433.1 - 2 7.2 9.3 4 6.2 9.3 1.4 1 0 0 1 1 1 0 Hsp90 protein Merozoite_SPAM PF07133.11 EMC92433.1 - 9.9 6.1 20.0 1.5 8.7 12.7 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Ino80_Iec3 PF14612.6 EMC92434.1 - 3.9e-63 214.3 0.2 1.7e-62 212.2 0.0 1.8 2 0 0 2 2 2 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling CDT1_C PF16679.5 EMC92434.1 - 0.16 12.5 2.7 3.1 8.3 0.7 2.4 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Spt20 PF12090.8 EMC92434.1 - 0.55 9.8 10.3 0.91 9.1 10.3 1.3 1 0 0 1 1 1 0 Spt20 family Uso1_p115_C PF04871.13 EMC92434.1 - 2.3 8.6 12.6 0.19 12.1 7.5 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Glyco_tran_28_C PF04101.16 EMC92435.1 - 5.3e-19 68.8 0.1 1.3e-18 67.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.9 EMC92436.1 - 6.6e-42 142.9 0.0 8.7e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Zn_clus PF00172.18 EMC92438.1 - 0.7 10.1 5.2 1.2 9.3 5.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AIM24 PF01987.17 EMC92440.1 - 2.3e-49 167.9 0.3 2.8e-49 167.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Aldo_ket_red PF00248.21 EMC92441.1 - 6.5e-67 225.8 0.0 7.4e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family eIF-5_eIF-2B PF01873.17 EMC92442.1 - 1.4e-41 141.1 0.2 2.2e-41 140.4 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EMC92442.1 - 0.11 12.0 0.8 0.22 11.0 0.8 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 EMC92442.1 - 2 8.8 7.6 1.3 9.4 0.4 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.12 EMC92442.1 - 2.6 7.9 5.9 24 4.8 3.9 2.8 2 1 1 3 3 3 0 HypF finger DUF678 PF05077.12 EMC92442.1 - 3.4 7.8 14.2 5.5 7.2 0.2 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF678) Spore_coat_CotO PF14153.6 EMC92442.1 - 8.6 6.2 11.2 15 5.4 11.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO IFRD PF05004.13 EMC92445.1 - 8.2e-84 281.3 6.8 1e-83 281.0 6.8 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) FAA_hydro_N_2 PF18288.1 EMC92445.1 - 0.041 14.3 0.1 0.13 12.7 0.1 1.8 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 SMYLE_N PF18615.1 EMC92445.1 - 0.13 11.8 1.1 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain HCBP_related PF06594.11 EMC92445.1 - 0.56 10.2 1.9 23 5.0 0.2 3.0 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Sigma70_r1_1 PF03979.14 EMC92445.1 - 0.75 9.9 8.9 0.55 10.3 5.7 2.3 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 WD40 PF00400.32 EMC92446.1 - 6.7e-45 150.2 24.1 5e-09 36.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC92446.1 - 3.4e-09 36.9 0.5 0.051 13.9 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC92446.1 - 1.7e-06 27.0 4.6 0.031 12.9 0.0 4.8 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EMC92446.1 - 0.0023 16.9 0.0 14 4.5 0.0 3.9 1 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EMC92446.1 - 0.015 14.7 0.0 0.75 9.1 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PD40 PF07676.12 EMC92446.1 - 0.034 14.1 0.1 22 5.1 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PAN_4 PF14295.6 EMC92447.1 - 3.8e-11 42.7 9.1 2.8e-06 27.1 2.2 2.5 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 EMC92447.1 - 0.0013 18.8 6.0 0.13 12.4 1.3 2.6 2 0 0 2 2 2 2 PAN-like domain PAN_3 PF08277.12 EMC92447.1 - 0.088 12.6 7.5 0.62 9.9 1.2 2.4 2 0 0 2 2 2 0 PAN-like domain Thionin PF00321.17 EMC92447.1 - 6.1 7.4 9.1 2.6 8.6 1.4 2.9 2 0 0 2 2 2 0 Plant thionin DUF4588 PF15251.6 EMC92448.1 - 0.00016 21.5 3.9 0.00047 20.0 3.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) CH PF00307.31 EMC92449.1 - 5.1e-12 45.9 0.0 8.9e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Pox_A_type_inc PF04508.12 EMC92449.1 - 0.021 14.7 0.8 0.021 14.7 0.8 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Snf7 PF03357.21 EMC92450.1 - 1.1e-28 100.0 18.0 1.1e-28 100.0 18.0 2.5 1 1 1 2 2 2 1 Snf7 BBS2_N PF14781.6 EMC92450.1 - 0.13 12.1 0.7 0.3 11.0 0.7 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Ten1 PF12658.7 EMC92451.1 - 2.9e-27 95.0 0.0 3.4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 EMC92451.1 - 0.05 13.3 0.0 0.079 12.7 0.0 1.6 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit DUF218 PF02698.17 EMC92452.1 - 3.7e-06 27.0 0.0 4.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Chitin_synth_1 PF01644.17 EMC92453.1 - 1.7e-66 223.2 0.0 2.4e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EMC92453.1 - 4.1e-28 97.1 0.0 7e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EMC92453.1 - 3.2e-24 85.5 1.5 1.1e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EMC92453.1 - 3.7e-09 36.8 0.8 3.7e-09 36.8 0.8 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Adap_comp_sub PF00928.21 EMC92454.1 - 5.9e-58 196.3 0.0 7.2e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMC92454.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain NAD_binding_8 PF13450.6 EMC92455.1 - 1.7e-11 44.1 0.0 5.4e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EMC92455.1 - 7.5e-11 41.1 0.0 1.8e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMC92455.1 - 0.0044 16.2 0.0 0.023 13.9 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMC92455.1 - 0.035 14.1 0.2 3.7 7.5 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMC92455.1 - 0.076 12.2 0.0 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 EMC92456.1 - 4.3e-40 137.8 0.0 5.5e-38 130.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Terpene_synth_C PF03936.16 EMC92457.1 - 0.00023 20.6 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Aldedh PF00171.22 EMC92458.1 - 5.5e-74 249.3 0.0 6.6e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RDM PF11002.8 EMC92458.1 - 0.18 11.8 1.6 23 5.1 0.0 3.3 3 0 0 3 3 3 0 RFPL defining motif (RDM) Trehalase PF01204.18 EMC92459.1 - 5.4e-187 622.7 0.5 6.6e-187 622.4 0.5 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EMC92459.1 - 9.7e-15 54.0 0.7 9.7e-15 54.0 0.7 2.0 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain Pkinase PF00069.25 EMC92460.1 - 4.3e-62 209.9 0.0 5.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92460.1 - 7.1e-33 114.0 0.0 1e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMC92460.1 - 1.6e-05 23.9 0.0 2.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMC92460.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMC92460.1 - 0.021 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMC92460.1 - 0.033 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EMC92460.1 - 0.045 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EMC92460.1 - 0.14 11.8 0.0 0.33 10.5 0.0 1.5 2 0 0 2 2 2 0 RIO1 family peroxidase PF00141.23 EMC92461.1 - 2.6e-83 279.2 0.0 2.1e-43 148.7 0.0 2.4 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 EMC92461.1 - 0.0068 16.6 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain DUF2724 PF10893.8 EMC92461.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2724) TMEM234 PF10639.9 EMC92462.1 - 6.1e-29 100.4 0.1 8.9e-29 99.9 0.1 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 PhyH PF05721.13 EMC92463.1 - 1.2e-54 185.7 0.0 1.5e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Alpha-amylase PF00128.24 EMC92464.1 - 1.2e-54 186.1 1.2 1.7e-54 185.6 1.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EMC92464.1 - 3.7e-21 75.2 0.2 6.8e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 EMC92464.1 - 0.0044 16.2 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain TPR_1 PF00515.28 EMC92467.1 - 9.2e-39 129.7 30.1 0.00015 21.4 0.3 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EMC92467.1 - 3e-34 114.3 28.7 0.00042 20.2 0.1 11.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 EMC92467.1 - 1.1e-21 77.2 20.7 0.00031 21.3 0.0 7.6 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 EMC92467.1 - 1.4e-20 72.7 27.3 0.00054 19.6 0.1 8.6 7 2 3 10 10 10 7 TPR repeat TPR_17 PF13431.6 EMC92467.1 - 6.9e-19 66.8 10.9 0.00011 22.3 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMC92467.1 - 5.8e-18 63.6 28.2 0.024 14.8 0.1 9.9 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 EMC92467.1 - 2.3e-17 63.0 22.1 1.3e-05 25.4 0.0 7.6 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 EMC92467.1 - 2.2e-13 49.2 18.9 0.048 13.7 0.1 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMC92467.1 - 4.2e-13 49.6 20.0 1.9e-05 25.1 0.7 6.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EMC92467.1 - 2.5e-11 43.5 13.5 0.0028 17.7 0.3 6.3 5 1 1 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 EMC92467.1 - 1.7e-10 40.4 19.5 0.027 14.3 0.2 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EMC92467.1 - 7.8e-08 32.5 15.1 0.028 15.2 0.3 8.4 5 3 4 9 9 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EMC92467.1 - 2.4e-05 23.9 1.8 2.4e-05 23.9 1.8 2.8 2 1 0 3 3 3 1 MalT-like TPR region ANAPC3 PF12895.7 EMC92467.1 - 0.00026 21.2 22.3 0.064 13.5 0.5 5.8 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 EMC92467.1 - 0.0039 16.6 17.4 1.5 8.3 0.2 6.5 6 0 0 6 6 6 2 SHNi-TPR TPR_3 PF07720.12 EMC92467.1 - 0.091 12.8 18.3 2.1 8.4 0.3 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMC92467.1 - 0.12 13.0 26.0 3.5 8.5 0.0 8.8 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF3856 PF12968.7 EMC92467.1 - 0.19 11.8 9.6 5.4 7.1 0.0 4.9 4 1 1 5 5 5 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 EMC92467.1 - 0.55 11.0 7.1 1.7 9.5 0.0 4.3 4 0 0 4 4 4 0 Sel1 repeat MAS20 PF02064.15 EMC92467.1 - 5 7.2 14.3 26 4.9 0.1 5.4 4 1 2 6 6 6 0 MAS20 protein import receptor MIT PF04212.18 EMC92467.1 - 8.2 6.6 25.3 14 5.8 0.0 6.8 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain N_BRCA1_IG PF16158.5 EMC92468.1 - 2e-32 112.0 0.0 7.5e-32 110.1 0.0 2.1 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EMC92468.1 - 4.4e-21 74.4 50.2 3.9e-07 29.8 8.8 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 EMC92468.1 - 0.0077 16.5 35.1 0.013 15.8 4.0 4.5 4 0 0 4 4 4 3 C1 domain Btz PF09405.10 EMC92469.1 - 1.8e-20 73.5 5.6 1.8e-20 73.5 5.6 2.4 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding IHABP4_N PF16174.5 EMC92469.1 - 8.4 7.0 14.6 1.5 9.4 9.0 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal MFS_1 PF07690.16 EMC92470.1 - 1e-22 80.6 37.5 1e-22 80.6 37.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 EMC92470.1 - 0.0034 15.7 0.6 0.0034 15.7 0.6 1.9 2 0 0 2 2 2 1 BT1 family LELP1 PF15042.6 EMC92471.1 - 6.6 7.2 8.9 1.4 9.3 0.3 2.3 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 C2 PF00168.30 EMC92472.1 - 1.4e-15 57.5 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Asp PF00026.23 EMC92474.1 - 3.8e-07 29.8 0.3 5.5e-07 29.3 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.13 EMC92474.1 - 8.6e-05 21.6 0.1 0.00014 20.8 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein TMEM51 PF15345.6 EMC92474.1 - 0.00043 20.2 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 BatD PF13584.6 EMC92474.1 - 0.015 14.1 0.2 0.024 13.5 0.2 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF4017 PF13209.6 EMC92474.1 - 0.017 15.1 0.2 0.086 12.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) Amnionless PF14828.6 EMC92474.1 - 0.019 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4690 PF15756.5 EMC92474.1 - 0.027 15.0 0.8 0.1 13.2 0.1 2.3 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF2681 PF10883.8 EMC92474.1 - 0.03 14.7 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) TMEM154 PF15102.6 EMC92474.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Neurensin PF14927.6 EMC92474.1 - 0.045 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Neurensin SKG6 PF08693.10 EMC92474.1 - 0.073 12.5 1.7 0.17 11.3 1.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 EMC92474.1 - 0.077 13.9 0.0 0.17 12.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Oxidored_q2 PF00420.24 EMC92474.1 - 0.079 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Syndecan PF01034.20 EMC92474.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.11 EMC92474.1 - 0.088 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Podoplanin Stevor PF17410.2 EMC92474.1 - 0.25 10.8 0.0 0.46 10.0 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame VEGFR-2_TMD PF17988.1 EMC92474.1 - 0.54 9.7 2.1 0.96 8.9 2.1 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Med3 PF11593.8 EMC92476.1 - 3.1e-06 26.7 5.4 3.1e-06 26.7 5.4 6.0 4 2 0 4 4 4 1 Mediator complex subunit 3 fungal PUA PF01472.20 EMC92477.1 - 0.0016 18.4 0.4 0.82 9.7 0.1 2.7 1 1 2 3 3 3 2 PUA domain Aldolase PF01081.19 EMC92477.1 - 0.0075 15.7 2.5 0.01 15.3 2.5 1.2 1 0 0 1 1 1 1 KDPG and KHG aldolase A_amylase_inhib PF01356.19 EMC92477.1 - 0.29 11.2 5.4 2.1 8.4 0.4 2.5 1 1 1 2 2 2 0 Alpha amylase inhibitor Cytochrom_B558a PF05038.13 EMC92477.1 - 0.35 10.4 4.0 5.1 6.6 0.8 2.1 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit EMP24_GP25L PF01105.24 EMC92478.1 - 1.3e-43 149.1 0.0 1.5e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BTB PF00651.31 EMC92479.1 - 0.21 11.9 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain cNMP_binding PF00027.29 EMC92480.1 - 2.5e-41 139.6 0.1 3e-21 75.3 0.1 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EMC92480.1 - 3.5e-10 39.4 0.3 6.7e-10 38.5 0.3 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit CDT1_C PF16679.5 EMC92482.1 - 2.7e-15 56.6 0.5 9e-15 54.9 0.5 1.9 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Aminotran_4 PF01063.19 EMC92484.1 - 5.8e-23 81.9 0.0 9.6e-23 81.2 0.0 1.3 1 1 0 1 1 1 1 Amino-transferase class IV Gln-synt_C PF00120.24 EMC92485.1 - 4e-20 72.1 0.0 5e-16 58.6 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain TRP PF06011.12 EMC92486.1 - 3e-169 563.3 31.5 3.5e-169 563.0 31.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EMC92486.1 - 2.7e-39 134.7 0.6 4.4e-39 134.0 0.6 1.4 1 0 0 1 1 1 1 ML-like domain 2OG-FeII_Oxy_2 PF13532.6 EMC92488.1 - 1e-27 97.6 0.0 1.6e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EMC92488.1 - 3.7e-25 89.1 0.0 2.6e-24 86.3 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family DNA_pol_phi PF04931.13 EMC92488.1 - 9.7 4.1 8.4 13 3.7 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hydantoinase_B PF02538.14 EMC92489.1 - 1e-126 423.4 0.0 1.2e-125 419.8 0.0 2.2 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMC92489.1 - 3.8e-88 295.5 1.7 3.8e-88 295.5 1.7 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMC92489.1 - 1.6e-46 158.2 0.0 4.5e-44 150.3 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EMC92489.1 - 8.2e-05 21.4 0.3 0.04 12.5 0.2 2.3 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 EMC92489.1 - 0.037 13.5 0.3 0.75 9.2 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Ppx-GppA PF02541.16 EMC92489.1 - 0.36 10.2 3.3 0.23 10.9 0.1 2.0 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Apolipoprotein PF01442.18 EMC92489.1 - 3.2 7.6 7.1 2.2 8.1 1.4 2.8 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Amidase PF01425.21 EMC92490.1 - 8.8e-82 275.4 0.4 1.3e-59 202.4 0.0 2.2 2 0 0 2 2 2 2 Amidase COesterase PF00135.28 EMC92491.1 - 1.2e-35 123.4 0.3 1.4e-35 123.1 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC92491.1 - 0.00012 22.0 0.1 0.053 13.4 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sugar_tr PF00083.24 EMC92492.1 - 3.5e-74 250.3 24.9 4.3e-74 250.0 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC92492.1 - 3.3e-20 72.3 29.2 3.3e-20 72.3 29.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 EMC92493.1 - 7.4e-06 25.2 0.3 1.2e-05 24.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.20 EMC92494.1 - 2.1e-42 145.7 0.0 2.9e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EMC92494.1 - 2e-17 63.6 0.0 3.6e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Plus-3 PF03126.18 EMC92495.1 - 2.1e-32 111.9 0.0 7.5e-32 110.1 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain COQ7 PF03232.13 EMC92496.1 - 1.1e-68 230.4 0.4 1.3e-68 230.2 0.4 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EMC92496.1 - 0.00097 19.5 0.1 0.0019 18.6 0.1 1.6 1 1 0 1 1 1 1 Rubrerythrin UPF0184 PF03670.13 EMC92496.1 - 0.23 11.9 1.1 0.42 11.0 1.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) AAA_12 PF13087.6 EMC92499.1 - 5.7e-34 117.5 0.0 8.7e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMC92499.1 - 3.3e-18 66.4 0.1 3.1e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EMC92499.1 - 2.9e-08 33.7 0.0 3e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMC92499.1 - 6.2e-07 29.8 0.0 1.3e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EMC92499.1 - 3.4e-06 27.2 0.0 5.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EMC92499.1 - 4.7e-05 23.2 0.0 0.26 11.0 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EMC92499.1 - 0.00038 20.1 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EMC92499.1 - 0.0022 17.9 0.0 0.0077 16.1 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 EMC92499.1 - 0.0045 17.3 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EMC92499.1 - 0.0062 15.8 0.0 0.064 12.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EMC92499.1 - 0.0087 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 EMC92499.1 - 0.022 15.2 0.0 0.22 11.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMC92499.1 - 0.032 14.6 0.0 0.089 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EMC92499.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IlvN PF07991.12 EMC92500.1 - 1.6e-46 157.9 0.0 2.7e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EMC92500.1 - 1.8e-41 141.8 1.2 3e-41 141.1 1.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 EMC92500.1 - 0.032 14.8 0.0 0.087 13.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EMC92500.1 - 0.034 14.3 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CotJA PF11007.8 EMC92500.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) PLDc PF00614.22 EMC92501.1 - 6.7e-15 54.6 0.5 8.7e-07 28.9 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EMC92501.1 - 5e-14 52.3 0.0 7.3e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 EMC92501.1 - 9.6e-08 32.0 0.0 6.1e-07 29.4 0.0 2.3 2 1 0 2 2 2 1 PX domain PhoPQ_related PF10142.9 EMC92502.1 - 0.057 12.1 0.0 0.088 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PRELI PF04707.14 EMC92503.1 - 3.4e-21 75.7 0.0 4.4e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 PRELI-like family tRNA-synt_1b PF00579.25 EMC92504.1 - 1.4e-19 70.6 0.0 1.4e-18 67.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) SNF2_N PF00176.23 EMC92505.1 - 1e-75 254.6 0.1 2e-75 253.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EMC92505.1 - 2.2e-42 143.7 4.2 4.7e-40 136.2 0.3 3.0 2 0 0 2 2 2 2 SLIDE HAND PF09110.11 EMC92505.1 - 5e-33 114.2 0.4 5e-33 114.2 0.4 2.9 2 0 0 2 2 2 1 HAND Helicase_C PF00271.31 EMC92505.1 - 5.2e-18 65.4 0.1 4.5e-17 62.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC92505.1 - 3.1e-11 43.6 0.0 1.4e-10 41.4 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EMC92505.1 - 1.4e-05 24.5 0.2 5.1e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EMC92505.1 - 5.8e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EMC92505.1 - 0.00016 21.5 0.0 0.00079 19.2 0.0 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 EMC92505.1 - 0.0035 17.5 0.0 0.48 10.7 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Isochorismatase PF00857.20 EMC92505.1 - 0.0052 17.0 0.4 2.1 8.5 0.0 2.7 2 0 0 2 2 2 1 Isochorismatase family AAA_22 PF13401.6 EMC92505.1 - 0.0078 16.5 0.6 0.91 9.8 0.1 3.2 3 0 0 3 3 3 1 AAA domain DUF1086 PF06461.11 EMC92505.1 - 0.012 15.5 0.2 0.032 14.1 0.2 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) DEAD_2 PF06733.15 EMC92505.1 - 0.045 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 EMC92505.1 - 0.047 13.7 0.4 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain Ferric_reduct PF01794.19 EMC92507.1 - 5.5e-18 65.3 8.4 5.5e-18 65.3 8.4 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMC92507.1 - 4.9e-16 59.2 0.0 7.6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMC92507.1 - 1.2e-09 38.3 0.0 4.1e-09 36.5 0.0 2.0 2 1 0 2 2 2 1 FAD-binding domain DUF4337 PF14235.6 EMC92507.1 - 0.68 10.0 2.5 1.3 9.1 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2070 PF09843.9 EMC92507.1 - 0.87 7.8 7.0 1.2 7.3 7.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3147 PF11345.8 EMC92507.1 - 2.5 8.5 7.7 0.8 10.1 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) DUF3455 PF11937.8 EMC92508.1 - 1.2e-33 116.8 0.0 1.5e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) PCRF PF03462.18 EMC92513.1 - 5.9e-50 169.8 0.2 2.8e-49 167.6 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EMC92513.1 - 3.9e-32 110.6 3.8 3.9e-32 110.6 3.8 2.1 3 0 0 3 3 3 1 RF-1 domain Tup_N PF08581.10 EMC92513.1 - 0.1 12.9 1.3 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Tup N-terminal DUF3347 PF11827.8 EMC92513.1 - 0.56 10.4 2.0 0.55 10.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) TPX2 PF06886.11 EMC92513.1 - 0.64 10.3 5.4 1.9 8.8 5.4 1.8 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Transthyretin PF00576.21 EMC92515.1 - 2.2e-34 118.4 0.0 2.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family adh_short_C2 PF13561.6 EMC92516.1 - 3.4e-58 197.0 0.3 4e-58 196.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC92516.1 - 4.4e-41 140.5 0.7 5.2e-41 140.3 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EMC92516.1 - 0.0028 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SWIRM-assoc_3 PF16498.5 EMC92516.1 - 0.0035 17.5 0.3 0.012 15.8 0.3 1.9 1 0 0 1 1 1 1 SWIRM-associated domain at the C-terminal Polysacc_deac_1 PF01522.21 EMC92517.1 - 3.5e-24 85.1 0.0 4.8e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 EMC92517.1 - 0.0011 18.2 0.0 0.0031 16.7 0.0 1.7 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase Ribonuc_2-5A PF06479.12 EMC92517.1 - 0.055 13.7 0.1 0.64 10.2 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease 2-5A Peptidase_M20 PF01546.28 EMC92518.1 - 3.7e-31 108.4 0.0 1.1e-30 106.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMC92518.1 - 8.6e-14 51.4 0.0 1.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain FlaE PF07559.14 EMC92518.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Flagellar basal body protein FlaE Forkhead PF00250.18 EMC92520.1 - 9.7e-16 57.8 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain Pkinase PF00069.25 EMC92524.1 - 4.1e-75 252.5 0.0 5.6e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92524.1 - 1.1e-38 133.0 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EMC92524.1 - 1.1e-18 67.7 0.0 3.3e-07 30.8 0.0 3.5 3 0 0 3 3 3 3 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EMC92524.1 - 1.2e-14 54.1 0.1 2.5e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EMC92524.1 - 1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EMC92524.1 - 0.00044 19.9 0.5 0.0025 17.5 0.1 2.1 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 EMC92524.1 - 0.0027 16.7 0.2 0.0047 15.9 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMC92524.1 - 0.035 13.5 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 EMC92524.1 - 0.044 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 EMC92524.1 - 0.11 12.4 0.3 0.83 9.5 0.2 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family MARVEL PF01284.23 EMC92525.1 - 1.7e-20 73.5 10.0 2e-20 73.3 10.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF2304 PF10066.9 EMC92525.1 - 3.4 7.9 6.4 20 5.4 3.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Glyco_transf_28 PF03033.20 EMC92526.1 - 4e-17 62.6 0.2 1e-15 58.0 0.2 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EMC92526.1 - 8.1e-06 24.9 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EMC92526.1 - 0.0005 20.1 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SLATT_fungal PF18142.1 EMC92527.1 - 3.3e-10 40.0 0.3 4.8e-10 39.5 0.3 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SKG6 PF08693.10 EMC92530.1 - 6.7e-06 25.4 0.1 2.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain ATF7IP_BD PF16788.5 EMC92530.1 - 4 7.5 9.0 7.8 6.5 9.0 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain PhyH PF05721.13 EMC92531.1 - 2.3e-16 60.7 0.0 2.9e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EMC92531.1 - 0.046 14.1 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.24 EMC92532.1 - 2.6e-71 240.8 21.0 2.9e-71 240.7 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC92532.1 - 1.8e-12 46.9 26.6 1.8e-12 46.9 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tyr_Deacylase PF02580.16 EMC92533.1 - 2.7e-51 173.9 0.1 3.6e-51 173.5 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 EMC92534.1 - 2.7e-88 295.3 28.9 2.7e-88 295.3 28.9 1.5 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EMC92534.1 - 2.8e-41 140.6 9.5 7.7e-41 139.2 9.5 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.11 EMC92534.1 - 0.005 16.9 3.9 0.0084 16.1 0.7 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) CorA PF01544.18 EMC92534.1 - 0.0064 15.8 3.5 0.0064 15.8 3.5 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Syntaxin_2 PF14523.6 EMC92534.1 - 0.0077 16.6 3.7 0.0077 16.6 3.7 2.7 2 1 0 2 2 2 1 Syntaxin-like protein DUF2373 PF10180.9 EMC92534.1 - 0.031 14.1 1.5 0.081 12.8 1.5 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Sec5 PF15469.6 EMC92534.1 - 1.6 8.5 11.4 0.084 12.7 1.5 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 Cep57_MT_bd PF06657.13 EMC92534.1 - 3.7 8.1 10.2 7.1 7.2 1.8 3.0 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2524 PF10732.9 EMC92534.1 - 6.4 7.2 7.9 0.27 11.6 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) MFS_1 PF07690.16 EMC92535.1 - 1.1e-18 67.3 38.7 1.1e-18 67.3 38.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MIG-14_Wnt-bd PF06664.12 EMC92535.1 - 0.0042 16.3 1.9 0.027 13.7 0.5 2.2 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion ADH_N PF08240.12 EMC92536.1 - 1.1e-21 76.7 0.7 2.2e-21 75.8 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC92536.1 - 5.9e-13 48.9 0.0 9.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMC92536.1 - 6.2e-05 22.4 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMC92536.1 - 0.0067 15.8 0.0 0.0095 15.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EMC92536.1 - 0.031 14.1 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SAP PF02037.27 EMC92539.1 - 0.00091 18.9 0.1 0.0018 18.0 0.1 1.5 1 0 0 1 1 1 1 SAP domain WSK PF03832.13 EMC92539.1 - 0.082 12.6 0.1 0.082 12.6 0.1 2.2 3 0 0 3 3 3 0 WSK motif LTXXQ PF07813.12 EMC92540.1 - 0.15 12.8 1.4 0.18 12.6 1.4 1.2 1 0 0 1 1 1 0 LTXXQ motif family protein DUF3886 PF13025.6 EMC92540.1 - 0.19 11.9 3.4 0.46 10.7 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) ECR1_N PF14382.6 EMC92542.1 - 3.5e-13 49.1 0.2 8e-13 48.0 0.2 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EMC92542.1 - 2.2e-06 27.9 0.1 4.9e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 KH domain Apolipoprotein PF01442.18 EMC92544.1 - 0.0023 17.8 4.8 0.0038 17.1 4.8 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EMC92544.1 - 0.032 14.3 5.3 0.046 13.8 5.3 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) V-ATPase_G PF03179.15 EMC92544.1 - 0.048 14.2 5.6 0.07 13.7 5.6 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit BshC PF10079.9 EMC92544.1 - 0.18 10.5 3.2 0.21 10.3 3.2 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC HCV_NS4a PF01006.20 EMC92544.1 - 0.23 11.2 0.6 0.38 10.5 0.6 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a RRF PF01765.19 EMC92544.1 - 0.27 11.2 7.8 0.47 10.4 7.8 1.4 1 1 0 1 1 1 0 Ribosome recycling factor DUF883 PF05957.13 EMC92544.1 - 0.33 11.6 6.6 1.2 9.7 6.6 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Pilin PF00114.19 EMC92544.1 - 0.58 11.1 5.5 2.7 9.0 5.5 1.9 1 1 0 1 1 1 0 Pilin (bacterial filament) Arm-DNA-bind_3 PF13356.6 EMC92544.1 - 0.76 10.2 4.0 13 6.2 0.4 2.7 1 1 1 2 2 2 0 Arm DNA-binding domain DivIVA PF05103.13 EMC92544.1 - 0.92 9.6 7.5 0.37 10.9 1.5 2.0 1 1 1 2 2 2 0 DivIVA protein Pex24p PF06398.11 EMC92545.1 - 7.9e-07 28.4 7.8 1.4e-06 27.5 7.8 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin V_ATPase_I PF01496.19 EMC92545.1 - 7.9 4.3 9.0 0.18 9.7 2.0 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Nop14 PF04147.12 EMC92546.1 - 4.8 5.3 19.1 0.11 10.7 12.6 1.4 2 0 0 2 2 2 0 Nop14-like family ZZ PF00569.17 EMC92548.1 - 1e-05 25.2 6.2 1.7e-05 24.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SH3_1 PF00018.28 EMC92549.1 - 4.7e-15 54.9 0.0 7.5e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMC92549.1 - 4.6e-11 42.4 0.0 7.5e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMC92549.1 - 3.2e-08 33.1 0.0 5.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4004 PF13171.6 EMC92549.1 - 0.23 11.7 0.2 0.47 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4004) Iso_dh PF00180.20 EMC92550.1 - 1.1e-75 255.0 0.0 1.2e-75 254.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3253 PF11625.8 EMC92551.1 - 1.7e-13 50.6 0.0 1.9e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) AMP-binding PF00501.28 EMC92553.1 - 5.9e-08 31.7 0.0 6.5e-08 31.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme TrbE PF11100.8 EMC92554.1 - 0.25 11.6 0.3 0.25 11.6 0.3 1.6 2 0 0 2 2 2 0 Conjugal transfer protein TrbE Oxysterol_BP PF01237.18 EMC92555.1 - 2.3e-53 181.3 0.0 2.3e-46 158.3 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein FliG_N PF14842.6 EMC92555.1 - 0.12 13.0 0.0 0.3 11.6 0.0 1.6 2 0 0 2 2 2 0 FliG N-terminal domain ECH_1 PF00378.20 EMC92556.1 - 1.5e-38 132.5 0.0 4.2e-37 127.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMC92556.1 - 1.2e-26 94.0 0.0 2.6e-25 89.6 0.0 1.8 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase stn_TNFRSF12A PF12191.8 EMC92557.1 - 0.0076 16.5 2.2 0.016 15.4 1.3 1.9 1 1 1 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain GT87 PF09594.10 EMC92557.1 - 0.025 14.3 0.9 0.036 13.8 0.9 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 BatD PF13584.6 EMC92557.1 - 0.055 12.3 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF2207 PF09972.9 EMC92557.1 - 0.18 10.5 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GAPT PF11770.8 EMC92557.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) RCR PF12273.8 EMC92557.1 - 0.19 12.4 2.1 0.61 10.7 2.1 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red RNase_T PF00929.24 EMC92560.1 - 4.5e-28 98.9 0.0 5.1e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Sec63 PF02889.16 EMC92561.1 - 2e-136 453.2 0.0 1.3e-80 270.3 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EMC92561.1 - 9e-53 178.6 0.5 1.2e-26 93.6 0.6 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EMC92561.1 - 4e-22 79.0 0.0 1.3e-11 44.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMC92561.1 - 4e-17 62.5 0.0 7.5e-07 29.5 0.0 4.8 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EMC92561.1 - 4.4e-10 40.0 0.1 0.00012 22.3 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EMC92561.1 - 2.5e-07 30.6 0.4 0.01 15.6 0.4 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EMC92561.1 - 2.3e-06 28.0 0.8 0.0017 18.7 0.8 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EMC92561.1 - 5.3e-05 23.7 0.0 1.9 8.9 0.0 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 EMC92561.1 - 0.029 14.5 0.0 0.095 12.9 0.0 1.9 1 0 0 1 1 1 0 N-terminal helicase PWI domain IstB_IS21 PF01695.17 EMC92561.1 - 0.048 13.4 0.2 15 5.3 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein TniB PF05621.11 EMC92561.1 - 0.053 12.9 0.4 17 4.8 0.1 3.6 3 0 0 3 3 3 0 Bacterial TniB protein PhoH PF02562.16 EMC92561.1 - 0.086 12.3 0.1 7.1 6.0 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein Actin PF00022.19 EMC92562.1 - 6.2e-49 166.7 0.0 1.8e-27 96.0 0.0 2.4 2 1 0 2 2 2 2 Actin DUF3040 PF11239.8 EMC92562.1 - 1.8 8.9 3.2 0.8 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) 3HCDH_N PF02737.18 EMC92563.1 - 3.8e-50 170.3 0.1 6e-50 169.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EMC92563.1 - 1.5e-30 105.7 0.0 2.6e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 EMC92563.1 - 0.0038 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EMC92563.1 - 0.014 14.6 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EMC92563.1 - 0.05 13.8 0.2 0.1 12.7 0.2 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 EMC92563.1 - 0.1 12.2 0.8 0.37 10.3 0.8 1.9 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EMC92563.1 - 0.21 11.8 0.7 0.62 10.3 0.0 2.1 3 0 0 3 3 3 0 TrkA-N domain FAD_binding_3 PF01494.19 EMC92565.1 - 3.2e-07 29.9 0.6 1.3e-06 27.9 0.6 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EMC92565.1 - 0.018 14.1 0.0 0.071 12.2 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 EMC92565.1 - 0.044 13.0 0.0 0.44 9.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC92565.1 - 0.064 13.5 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC92565.1 - 0.072 12.7 0.0 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf-Sec23_Sec24 PF04810.15 EMC92565.1 - 0.14 12.3 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Na_H_antiporter PF03553.14 EMC92566.1 - 0.12 11.5 0.2 0.2 10.8 0.2 1.3 1 0 0 1 1 1 0 Na+/H+ antiporter family Lactamase_B PF00753.27 EMC92568.1 - 2.8e-10 40.5 0.9 8.2e-10 39.0 0.9 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMC92568.1 - 0.047 13.2 0.3 0.11 12.0 0.3 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain YL1_C PF08265.11 EMC92569.1 - 9.2e-16 57.3 0.9 1.7e-15 56.5 0.9 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ribosomal_S9 PF00380.19 EMC92570.1 - 4.2e-33 114.4 0.2 4.8e-33 114.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SMC_Nse1 PF07574.13 EMC92571.1 - 3.3e-64 216.4 0.2 4e-64 216.1 0.2 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EMC92571.1 - 4.8e-13 49.2 8.7 8.4e-13 48.4 8.7 1.4 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 EMC92571.1 - 0.00017 21.5 1.2 0.00029 20.8 1.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EMC92571.1 - 0.00062 20.0 6.4 0.0011 19.2 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain C1_1 PF00130.22 EMC92571.1 - 0.029 14.2 1.6 0.029 14.2 1.6 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 EMC92571.1 - 0.86 9.9 4.3 2 8.8 4.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EMC92571.1 - 1.6 8.7 4.7 4 7.4 4.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC92571.1 - 2.4 8.2 6.7 5.6 7.0 6.7 1.7 1 1 0 1 1 1 0 zinc-RING finger domain TIMELESS PF04821.14 EMC92572.1 - 7.6e-89 297.6 1.3 1.9e-88 296.4 1.3 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 EMC92572.1 - 1.5e-15 57.4 0.0 1.5e-15 57.4 0.0 4.6 2 1 1 3 3 3 1 Timeless protein C terminal region F-box PF00646.33 EMC92573.1 - 0.034 14.0 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EMC92573.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like K_oxygenase PF13434.6 EMC92574.1 - 2.1e-106 355.9 0.0 2.6e-106 355.6 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMC92574.1 - 6.9e-06 25.5 0.0 0.00025 20.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC92574.1 - 1.6e-05 24.9 0.0 0.0029 17.6 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMC92574.1 - 0.00013 21.4 0.0 0.0029 16.9 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.6 EMC92574.1 - 0.16 11.5 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) ABC_membrane PF00664.23 EMC92576.1 - 1.3e-79 267.7 22.0 9.9e-43 146.7 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMC92576.1 - 4.9e-61 205.2 0.0 2.4e-31 109.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMC92576.1 - 4.7e-10 39.3 5.5 0.0011 18.5 0.0 4.1 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMC92576.1 - 1.2e-06 28.6 0.9 0.56 10.0 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 EMC92576.1 - 2.3e-06 26.7 0.5 0.028 13.2 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EMC92576.1 - 5.7e-05 23.1 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EMC92576.1 - 6.7e-05 22.7 0.1 0.015 15.0 0.0 3.3 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMC92576.1 - 7e-05 23.3 4.1 0.0055 17.1 0.3 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMC92576.1 - 0.0019 18.5 0.5 0.27 11.5 0.1 3.6 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.6 EMC92576.1 - 0.0054 16.5 3.4 1.5 8.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EMC92576.1 - 0.0088 15.3 0.1 1.3 8.2 0.0 2.5 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.6 EMC92576.1 - 0.024 14.8 0.1 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMC92576.1 - 0.035 13.7 2.7 3.4 7.2 0.5 3.4 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EMC92576.1 - 0.038 13.7 0.0 1.4 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.15 EMC92576.1 - 0.17 11.8 0.0 7.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 EMC92576.1 - 0.21 12.0 0.2 22 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EMC92576.1 - 0.23 11.6 0.4 38 4.4 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase HTH_Tnp_1 PF01527.20 EMC92576.1 - 1.5 9.2 3.1 78 3.7 0.0 3.7 4 0 0 4 4 4 0 Transposase AMP-binding PF00501.28 EMC92577.1 - 2.1e-227 754.7 0.0 8e-84 281.7 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EMC92577.1 - 2.9e-189 629.5 0.0 6.2e-37 127.4 0.0 7.7 6 2 0 6 6 6 6 Condensation domain PP-binding PF00550.25 EMC92577.1 - 1.3e-54 182.4 7.4 1.9e-09 37.7 0.2 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EMC92577.1 - 4.4e-12 46.8 0.0 0.02 15.8 0.0 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EMC92577.1 - 0.025 13.2 0.0 2.5 6.7 0.0 3.5 4 0 0 4 4 4 0 Transferase family Sigma54_DBD PF04552.13 EMC92577.1 - 0.12 12.1 0.1 0.44 10.2 0.1 1.9 1 0 0 1 1 1 0 Sigma-54, DNA binding domain DUF190 PF02641.15 EMC92577.1 - 0.17 12.2 0.2 4.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized ACR, COG1993 AAA_33 PF13671.6 EMC92577.1 - 8.6 6.5 6.7 4.5 7.4 1.1 2.9 2 1 0 2 2 2 0 AAA domain PGM_PMM_I PF02878.16 EMC92579.1 - 8e-15 54.8 0.9 4.3e-07 29.7 0.0 2.7 2 1 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EMC92579.1 - 8.3e-09 35.5 1.0 5.1e-08 33.0 0.1 2.8 4 0 0 4 4 4 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 EMC92579.1 - 1.2e-06 29.1 0.4 5.2e-05 23.8 0.1 2.9 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EMC92579.1 - 0.0021 18.2 0.1 0.0047 17.1 0.1 1.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III AAA PF00004.29 EMC92580.1 - 3.4e-59 199.0 0.0 3.7e-41 140.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMC92580.1 - 4.8e-14 51.9 2.1 4.6e-06 26.3 0.5 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EMC92580.1 - 3.4e-10 40.6 0.9 0.00017 22.0 0.0 4.5 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EMC92580.1 - 8.2e-08 32.6 1.3 0.017 15.4 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_7 PF12775.7 EMC92580.1 - 8.9e-07 28.6 0.0 0.0041 16.6 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region DUF815 PF05673.13 EMC92580.1 - 1.2e-05 24.6 0.0 0.013 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_5 PF07728.14 EMC92580.1 - 1.2e-05 25.3 0.1 0.0046 17.0 0.0 3.3 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMC92580.1 - 0.00016 21.9 0.0 0.00054 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EMC92580.1 - 0.00018 21.0 0.0 0.19 11.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EMC92580.1 - 0.00019 21.2 0.0 0.044 13.5 0.0 3.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Bac_DnaA PF00308.18 EMC92580.1 - 0.00023 21.1 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial dnaA protein Sigma54_activat PF00158.26 EMC92580.1 - 0.00029 20.6 0.0 0.018 14.7 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 EMC92580.1 - 0.00059 19.5 0.1 0.35 10.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 EMC92580.1 - 0.0028 17.6 0.6 5.6 6.9 0.0 3.6 2 1 1 3 3 3 1 NACHT domain TIP49 PF06068.13 EMC92580.1 - 0.0034 16.7 0.0 0.018 14.3 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain DAP3 PF10236.9 EMC92580.1 - 0.0066 15.7 0.0 0.06 12.5 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 CDC48_N PF02359.18 EMC92580.1 - 0.0082 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RNA_helicase PF00910.22 EMC92580.1 - 0.01 16.2 0.0 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 EMC92580.1 - 0.012 15.0 0.0 0.29 10.5 0.0 2.9 3 1 0 4 4 4 0 Bacterial TniB protein DUF5038 PF16441.5 EMC92580.1 - 0.013 15.6 0.1 0.041 13.9 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5038) ABC_tran PF00005.27 EMC92580.1 - 0.019 15.5 0.1 1.7 9.1 0.1 3.0 3 1 0 3 3 2 0 ABC transporter AAA_3 PF07726.11 EMC92580.1 - 0.023 14.6 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EMC92580.1 - 0.043 13.8 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Rad17 PF03215.15 EMC92580.1 - 0.044 13.7 0.0 0.36 10.7 0.0 2.4 2 1 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EMC92580.1 - 0.055 13.5 0.0 0.53 10.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 EMC92580.1 - 0.057 13.5 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EMC92580.1 - 0.071 12.8 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EMC92580.1 - 0.091 12.7 0.4 27 4.6 0.0 3.5 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EMC92580.1 - 0.13 12.0 0.1 12 5.5 0.0 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein ATPase PF06745.13 EMC92580.1 - 0.14 11.4 0.0 29 3.9 0.0 3.0 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.22 EMC92580.1 - 0.21 10.7 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Arm PF00514.23 EMC92582.1 - 0.0077 16.3 0.1 0.047 13.7 0.1 2.5 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 EMC92582.1 - 0.025 14.6 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central Ric8 PF10165.9 EMC92582.1 - 0.13 11.2 0.0 0.33 9.9 0.0 1.7 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn DPM3 PF08285.11 EMC92583.1 - 3e-38 129.9 0.0 3.3e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1349 PF07081.11 EMC92585.1 - 2.3e-33 115.4 0.0 2.7e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Brr6_like_C_C PF10104.9 EMC92586.1 - 2.1e-48 163.5 5.3 2.9e-48 163.0 5.3 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Dynamin_N PF00350.23 EMC92587.1 - 2.7e-27 95.9 0.6 1.2e-26 93.8 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EMC92587.1 - 5.9e-25 88.1 0.0 3.6e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 EMC92587.1 - 5.6e-05 23.2 0.8 5.6e-05 23.2 0.8 2.5 2 1 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EMC92587.1 - 0.0023 18.0 0.1 0.046 13.8 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase VASP_tetra PF08776.11 EMC92587.1 - 0.13 11.8 0.8 0.37 10.4 0.8 1.7 1 0 0 1 1 1 0 VASP tetramerisation domain Adaptin_N PF01602.20 EMC92589.1 - 4.7e-124 414.8 9.9 5.8e-124 414.5 9.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EMC92589.1 - 5.8e-40 136.0 0.0 1.3e-39 134.8 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EMC92589.1 - 2.2e-16 60.1 0.0 4.3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EMC92589.1 - 0.00019 21.5 3.0 0.083 12.9 0.0 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMC92589.1 - 0.0042 17.4 0.3 3.8 8.0 0.0 4.6 4 2 1 5 5 5 1 HEAT repeats RTP1_C1 PF10363.9 EMC92589.1 - 0.05 13.8 0.6 0.6 10.3 0.3 2.9 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 EMC92589.1 - 0.26 11.7 4.3 9 6.7 0.2 3.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TFIIB PF00382.19 EMC92590.1 - 1.5e-30 105.1 2.6 7.4e-19 67.6 0.2 3.3 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EMC92590.1 - 8.3e-21 74.2 5.4 8.3e-21 74.2 5.4 3.9 3 1 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 EMC92590.1 - 0.026 14.2 0.2 0.2 11.4 0.0 2.2 1 1 1 2 2 2 0 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.12 EMC92590.1 - 0.49 10.0 3.2 1.2 8.7 3.2 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Fucose_iso_N2 PF07882.12 EMC92590.1 - 0.83 9.2 3.9 38 3.8 0.6 3.3 3 0 0 3 3 3 0 L-fucose isomerase, second N-terminal domain DUF664 PF04978.12 EMC92590.1 - 0.93 9.9 4.7 3.7 7.9 4.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF664) BTB PF00651.31 EMC92591.1 - 5.9e-05 23.3 0.0 0.0018 18.5 0.0 2.1 1 1 1 2 2 2 2 BTB/POZ domain PHD PF00628.29 EMC92592.1 - 1.7e-11 43.8 7.3 2.6e-11 43.2 7.3 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EMC92592.1 - 0.00022 21.1 3.3 0.00022 21.1 3.3 1.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 EMC92592.1 - 0.0025 17.4 1.7 0.0052 16.4 1.7 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 EMC92592.1 - 0.015 14.8 7.4 0.068 12.7 7.4 2.1 1 1 0 1 1 1 0 PHD-finger FYVE_2 PF02318.16 EMC92592.1 - 0.074 13.3 1.2 0.12 12.6 1.2 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 EMC92592.1 - 0.096 12.6 4.2 0.13 12.2 1.0 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-piccolo PF05715.13 EMC92592.1 - 0.15 12.2 3.6 0.29 11.3 3.6 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RRPl_C4 PF17026.5 EMC92592.1 - 1.7 8.8 4.3 16 5.7 4.3 2.0 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type PHD_4 PF16866.5 EMC92592.1 - 4.9 7.3 7.7 14 5.9 7.7 1.8 1 1 0 1 1 1 0 PHD-finger BTB PF00651.31 EMC92593.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain zf-BED PF02892.15 EMC92595.1 - 0.017 15.1 0.2 0.046 13.8 0.2 1.6 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.6 EMC92595.1 - 0.1 13.5 9.3 0.31 12.0 2.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EMC92595.1 - 0.87 9.8 3.9 0.64 10.2 0.2 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 EMC92595.1 - 2.4 8.8 8.9 0.9 10.1 0.5 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EMC92595.1 - 5.3 6.9 5.8 0.52 10.1 0.5 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF4689 PF15755.5 EMC92600.1 - 0.12 12.0 3.8 0.15 11.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) Lum_binding PF00677.17 EMC92603.1 - 2.5e-45 152.4 3.5 6.7e-23 80.5 0.4 2.2 2 0 0 2 2 2 2 Lumazine binding domain CoA_transf_3 PF02515.17 EMC92604.1 - 7e-119 397.2 0.0 7.9e-119 397.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Mac PF12464.8 EMC92604.1 - 0.17 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Maltose acetyltransferase Bud13 PF09736.9 EMC92605.1 - 9.1e-48 162.3 11.7 9.1e-48 162.3 11.7 2.9 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DNA_binding_1 PF01035.20 EMC92606.1 - 7.5e-24 83.7 0.1 1e-23 83.3 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain F-box PF00646.33 EMC92607.1 - 1.8e-05 24.5 0.2 5.4e-05 23.0 0.2 1.8 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMC92607.1 - 0.0038 17.1 0.2 0.0038 17.1 0.2 2.5 3 0 0 3 3 3 1 F-box-like AMP-binding PF00501.28 EMC92608.1 - 3.5e-79 266.4 0.0 4.8e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC92608.1 - 1.6e-13 51.4 0.3 3.5e-13 50.3 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sep15_SelM PF08806.11 EMC92608.1 - 0.092 12.9 0.2 0.88 9.8 0.1 2.4 2 0 0 2 2 2 0 Sep15/SelM redox domain adh_short PF00106.25 EMC92609.1 - 0.0017 17.9 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC92609.1 - 0.074 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 KR domain Abhydrolase_3 PF07859.13 EMC92610.1 - 1.8e-37 129.2 0.4 1.3e-27 97.1 0.3 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMC92610.1 - 5.5e-14 51.8 0.0 8.1e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EMC92610.1 - 0.0059 15.5 0.5 0.053 12.4 0.5 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC92611.1 - 4.8e-46 157.3 0.0 1.1e-45 156.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC92611.1 - 6.4e-08 31.9 0.1 1.5e-07 30.7 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 EMC92611.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EMC92611.1 - 0.17 11.4 0.3 0.49 9.8 0.0 1.9 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF1772 PF08592.11 EMC92612.1 - 1.6e-13 51.1 0.2 1.9e-13 50.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) COX2-transmemb PF09125.10 EMC92612.1 - 0.11 12.3 0.5 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane TALPID3 PF15324.6 EMC92612.1 - 0.23 9.1 0.0 0.26 8.9 0.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target YiaAB PF05360.14 EMC92612.1 - 0.33 11.2 0.3 0.33 11.2 0.3 2.1 3 0 0 3 3 3 0 yiaA/B two helix domain RRM_1 PF00076.22 EMC92613.1 - 1.5e-08 34.3 0.0 2.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMC92613.1 - 1.8e-06 27.8 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EMC92613.1 - 0.00019 21.2 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EMC92613.1 - 0.035 14.1 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif PAP2 PF01569.21 EMC92614.1 - 0.028 14.2 0.6 0.072 12.9 0.6 1.7 1 0 0 1 1 1 0 PAP2 superfamily Lipoxygenase PF00305.19 EMC92615.1 - 0.26 9.7 0.1 0.34 9.3 0.1 1.1 1 0 0 1 1 1 0 Lipoxygenase Fungal_TACC PF12709.7 EMC92616.1 - 1.6e-08 34.9 22.6 3.4e-08 33.8 1.7 4.0 4 0 0 4 4 4 3 Fungal Transforming acidic coiled-coil (TACC) proteins RFXA_RFXANK_bdg PF15289.6 EMC92616.1 - 8.4 6.7 9.3 1.5 9.1 5.0 2.0 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain DbpA PF03880.15 EMC92617.1 - 0.0057 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain PKD_channel PF08016.12 EMC92617.1 - 0.099 11.3 0.2 0.14 10.8 0.2 1.1 1 0 0 1 1 1 0 Polycystin cation channel Phage_holin_3_6 PF07332.11 EMC92617.1 - 0.16 12.0 3.1 0.3 11.1 3.1 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ATP-grasp_2 PF08442.10 EMC92620.1 - 1.9e-75 252.8 2.0 1.9e-75 252.8 2.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EMC92620.1 - 3.1e-26 92.0 0.4 8.2e-26 90.7 0.4 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EMC92620.1 - 1.2e-09 37.9 0.5 3.7e-09 36.4 0.5 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EMC92620.1 - 0.0004 20.2 1.0 0.034 13.9 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EMC92620.1 - 0.0049 16.5 0.0 0.29 10.7 0.0 3.1 3 0 0 3 3 3 1 RimK-like ATP-grasp domain VID27_N PF17748.1 EMC92620.1 - 0.033 14.0 0.8 0.058 13.2 0.8 1.3 1 0 0 1 1 1 0 VID27 N-terminal region adh_short PF00106.25 EMC92621.1 - 2.9e-44 150.9 0.1 3.6e-44 150.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC92621.1 - 2.5e-31 109.0 0.0 2.8e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC92621.1 - 2.1e-12 47.3 0.7 2.7e-12 47.0 0.7 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMC92621.1 - 1.2e-05 25.3 0.5 2.2e-05 24.4 0.5 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC92621.1 - 0.00036 20.1 0.4 0.0028 17.2 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC92621.1 - 0.0052 16.0 0.0 0.0079 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 EMC92621.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain DUF1776 PF08643.10 EMC92621.1 - 0.2 11.0 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DAO PF01266.24 EMC92622.1 - 8.1e-48 163.8 2.6 9.3e-48 163.6 2.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMC92622.1 - 4.3e-06 27.2 0.0 0.014 15.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC92622.1 - 0.00023 20.5 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC92622.1 - 0.00044 20.4 1.9 0.00097 19.3 0.1 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 EMC92622.1 - 0.0011 17.8 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 MCRA family ApbA PF02558.16 EMC92622.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EMC92622.1 - 0.089 11.6 0.1 0.4 9.5 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase LuxS PF02664.15 EMC92622.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) Sacchrp_dh_NADP PF03435.18 EMC92622.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TPR_1 PF00515.28 EMC92626.1 - 2.8e-13 49.1 5.2 2.1e-06 27.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMC92626.1 - 1e-12 47.1 3.3 0.00021 21.2 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 EMC92626.1 - 5.7e-11 42.2 0.1 1e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.6 EMC92626.1 - 5.3e-10 39.4 0.3 2.2e-06 27.8 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMC92626.1 - 3.5e-08 33.0 0.2 0.00063 19.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMC92626.1 - 1.2e-07 31.9 0.7 0.67 10.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMC92626.1 - 3.1e-05 23.5 0.5 0.00043 19.9 0.2 2.8 1 1 1 2 2 2 1 TPR repeat TPR_9 PF13371.6 EMC92626.1 - 0.001 19.2 1.3 0.69 10.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMC92626.1 - 0.0051 16.7 0.1 0.49 10.5 0.1 3.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMC92626.1 - 0.013 15.8 0.2 3.2 8.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMC92626.1 - 0.29 11.8 0.1 0.29 11.8 0.1 3.3 3 1 1 4 4 2 0 Tetratricopeptide repeat LON_substr_bdg PF02190.16 EMC92627.1 - 5.2e-25 88.5 0.0 8.8e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EMC92627.1 - 3.7e-12 45.9 20.0 1.7e-09 37.3 11.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC92627.1 - 7.5e-11 41.9 22.2 2.2e-07 30.8 8.5 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 EMC92627.1 - 3.8e-10 39.5 19.8 1.2e-06 28.3 10.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC92627.1 - 4.6e-10 39.3 22.4 2.7e-06 27.2 9.3 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EMC92627.1 - 8.5e-10 38.6 19.6 4.7e-07 29.9 6.0 2.9 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EMC92627.1 - 1.2e-09 37.8 20.0 1.8e-07 30.9 8.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC92627.1 - 5.5e-08 33.0 22.5 1.9e-06 28.1 10.0 2.6 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 EMC92627.1 - 3.7e-07 29.9 16.4 6.3e-05 22.8 7.9 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EMC92627.1 - 0.00087 19.4 7.6 0.00087 19.4 7.6 2.5 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 EMC92627.1 - 0.0046 17.1 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.6 EMC92627.1 - 0.0076 16.0 5.6 0.0076 16.0 5.6 3.5 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EMC92627.1 - 0.019 14.6 8.5 0.019 14.6 8.5 2.8 2 1 1 3 3 3 0 P-11 zinc finger zf-RING_6 PF14835.6 EMC92627.1 - 0.044 13.7 10.6 0.24 11.3 2.1 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 EMC92627.1 - 3 7.8 7.5 0.17 11.8 0.4 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) HMA PF00403.26 EMC92628.1 - 3.4e-12 46.6 0.0 5.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EMC92628.1 - 2.3e-11 44.0 0.0 3.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.18 EMC92629.1 - 5.1e-46 156.0 0.0 6.3e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 EMC92630.1 - 2.1e-81 270.7 0.9 2.4e-43 147.5 0.6 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.6 EMC92631.1 - 3.4e-119 398.2 4.2 4.4e-119 397.8 0.1 3.1 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EMC92631.1 - 2.6e-38 130.0 0.2 1.1e-35 121.5 0.1 4.4 3 1 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EMC92631.1 - 1.4e-37 128.4 0.0 1.4e-34 118.7 0.0 4.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EMC92631.1 - 5.6e-30 103.4 1.7 2.1e-27 95.1 0.1 4.0 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EMC92631.1 - 2e-11 43.8 15.5 4.7e-11 42.6 15.0 2.0 1 1 0 1 1 1 1 Hr1 repeat MRPL52 PF18699.1 EMC92631.1 - 0.25 11.6 8.4 0.68 10.2 8.4 1.8 1 0 0 1 1 1 0 Mitoribosomal protein mL52 TFIIA PF03153.13 EMC92631.1 - 0.51 10.3 12.5 0.94 9.4 12.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 EMC92632.1 - 1.9e-24 86.3 26.0 1.9e-24 86.3 26.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mannosyl_trans3 PF11051.8 EMC92633.1 - 8.6e-55 186.0 0.0 1.6e-36 126.1 0.0 2.7 2 1 1 3 3 3 2 Mannosyltransferase putative CN_hydrolase PF00795.22 EMC92635.1 - 1.5e-24 86.8 0.1 2e-24 86.4 0.1 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Band_7_C PF16200.5 EMC92635.1 - 0.056 13.5 0.5 0.21 11.7 0.0 2.3 3 1 0 3 3 3 0 C-terminal region of band_7 Paf67 PF10255.9 EMC92636.1 - 4.3e-156 520.0 0.1 5e-156 519.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EMC92636.1 - 0.0021 18.0 0.0 0.012 15.7 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMC92636.1 - 0.016 15.0 0.0 0.084 12.7 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMC92636.1 - 0.13 12.6 0.2 4.9 7.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MRP-S27 PF10037.9 EMC92637.1 - 0.036 12.9 0.0 0.038 12.9 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 HET PF06985.11 EMC92640.1 - 4.1e-20 72.6 0.0 4.7e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ala_racemase_N PF01168.20 EMC92641.1 - 2.8e-25 89.3 0.1 3.5e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MAPEG PF01124.18 EMC92642.1 - 8.2e-17 61.3 0.7 1e-16 61.0 0.7 1.2 1 0 0 1 1 1 1 MAPEG family Longin PF13774.6 EMC92643.1 - 2.8e-14 52.9 0.0 4.9e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EMC92643.1 - 3e-11 43.0 0.1 5.1e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin RCC1 PF00415.18 EMC92644.1 - 8e-33 112.8 24.5 6.4e-09 36.3 0.7 7.4 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMC92644.1 - 1.2e-23 82.4 29.4 9.2e-08 31.7 1.5 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 EMC92645.1 - 5.7e-11 42.4 0.0 6.4e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Rad9 Phos_pyr_kin PF08543.12 EMC92647.1 - 7.8e-80 267.8 0.5 1.3e-79 267.0 0.5 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EMC92647.1 - 4.5e-54 183.5 1.0 6.6e-54 182.9 1.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EMC92647.1 - 8e-06 25.4 0.1 5.5e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase zf-C2H2 PF00096.26 EMC92649.1 - 0.1 13.1 0.2 0.21 12.1 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type U79_P34 PF03064.16 EMC92649.1 - 0.44 9.9 4.5 0.63 9.4 4.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Rrn6 PF10214.9 EMC92649.1 - 0.96 7.9 7.4 1.2 7.6 7.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1682 PF07946.14 EMC92649.1 - 0.99 8.5 8.5 1.2 8.3 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DEAD PF00270.29 EMC92651.1 - 2.7e-50 170.5 0.0 2.4e-49 167.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC92651.1 - 1.2e-31 109.3 0.0 6.4e-31 107.0 0.0 2.2 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC92651.1 - 5.6e-05 23.2 0.0 0.00031 20.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EMC92651.1 - 0.0013 19.0 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Helicase_C_2 PF13307.6 EMC92651.1 - 0.0075 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain UTP25 PF06862.12 EMC92651.1 - 0.015 14.1 0.1 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF2313 PF10076.9 EMC92651.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) TT_ORF2 PF02957.15 EMC92652.1 - 0.046 14.6 0.3 0.062 14.2 0.3 1.4 1 1 0 1 1 1 0 TT viral ORF2 Utp21 PF04192.12 EMC92653.1 - 1.4e-70 237.4 0.0 2.1e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EMC92653.1 - 2.3e-12 47.2 20.5 0.1 13.5 0.0 9.6 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC92653.1 - 1.1e-11 44.9 0.0 0.69 10.3 0.0 7.2 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EMC92653.1 - 0.071 13.1 0.5 1.9 8.5 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_trans_2_3 PF13632.6 EMC92654.1 - 1.9e-51 174.8 0.6 1.9e-51 174.8 0.6 2.6 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMC92654.1 - 0.0021 17.9 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.21 EMC92656.1 - 6.3e-18 64.9 0.3 9.8e-18 64.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WSC PF01822.19 EMC92658.1 - 6.2e-79 260.2 90.1 1.1e-17 64.0 11.5 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 EMC92658.1 - 2.7e-23 82.4 0.0 1.1e-21 77.1 0.0 2.6 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EMC92658.1 - 2.7e-20 72.5 0.1 6.1e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF4718 PF15842.5 EMC92658.1 - 7.1 6.4 5.3 0.76 9.5 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Tom6 PF17112.5 EMC92659.1 - 3.3e-06 26.5 0.0 3.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal Dus PF01207.17 EMC92665.1 - 1.3e-55 188.7 0.0 1.8e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Glycos_transf_2 PF00535.26 EMC92666.1 - 1.4e-31 109.6 0.0 1.8e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMC92666.1 - 6.6e-09 36.0 0.0 5.1e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMC92666.1 - 1.4e-05 24.7 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cyclin_N PF00134.23 EMC92667.1 - 0.00026 20.7 0.0 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EMC92667.1 - 0.067 13.2 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Sugar_tr PF00083.24 EMC92668.1 - 1.8e-66 224.9 27.3 2.1e-66 224.7 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC92668.1 - 2e-09 36.9 45.3 3.4e-08 32.8 38.6 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMC92668.1 - 0.0042 16.0 17.8 0.0052 15.7 5.7 2.6 3 0 0 3 3 3 2 MFS_1 like family Ferritin_2 PF13668.6 EMC92669.1 - 1.4e-18 67.4 0.0 2.7e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain TRM PF02005.16 EMC92670.1 - 1.7e-111 373.0 0.0 6.1e-95 318.6 0.0 2.0 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 EMC92670.1 - 0.014 15.0 0.0 0.044 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EMC92670.1 - 0.036 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 EMC92670.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein ISN1 PF06437.11 EMC92671.1 - 4.5e-196 651.6 0.0 5e-196 651.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Med17 PF10156.9 EMC92672.1 - 4.8e-86 289.3 0.0 6.8e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.20 EMC92673.1 - 1e-193 641.9 0.6 4.1e-107 357.7 0.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 EMC92673.1 - 0.041 13.5 0.2 0.23 11.1 0.1 2.3 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain PI3_PI4_kinase PF00454.27 EMC92674.1 - 4.5e-52 177.4 0.0 8e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 EMC92674.1 - 1.1e-27 96.0 1.8 5.2e-27 93.8 0.7 2.9 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 EMC92674.1 - 1.8e-26 93.2 1.3 3.2e-26 92.4 1.3 1.4 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 EMC92674.1 - 5e-13 48.6 0.0 1.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 FATC domain MS_channel PF00924.18 EMC92675.1 - 1.7e-15 57.2 3.2 3e-15 56.3 3.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EMC92675.1 - 4.3e-05 22.8 0.1 0.00011 21.5 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EMC92675.1 - 0.0021 17.8 0.0 0.0076 16.1 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EMC92675.1 - 0.003 18.0 0.0 0.008 16.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EMC92675.1 - 0.027 14.0 0.1 0.066 12.7 0.1 1.6 1 0 0 1 1 1 0 EF hand Metallophos PF00149.28 EMC92676.1 - 2.2e-18 67.5 0.6 3.8e-18 66.8 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EMC92676.1 - 6.9e-16 58.9 0.4 6.9e-16 58.9 0.4 2.6 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EMC92676.1 - 1.9e-15 57.2 8.9 1.9e-15 57.2 8.9 2.9 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EMC92676.1 - 0.0064 17.0 0.4 0.0064 17.0 0.4 2.6 3 0 0 3 3 3 1 PhoD-like phosphatase, N-terminal domain Hexokinase_2 PF03727.16 EMC92677.1 - 1.1e-56 192.0 0.0 1.4e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EMC92677.1 - 6.1e-19 68.7 0.0 8.4e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.16 EMC92678.1 - 2.4e-10 39.9 32.6 4.1e-10 39.1 32.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMC92678.1 - 2.2e-09 37.2 9.5 2.2e-09 37.2 9.5 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Glucosamine_iso PF01182.20 EMC92679.1 - 8.5e-20 71.6 0.0 1.4e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ATG22 PF11700.8 EMC92680.1 - 4.5e-133 444.4 29.3 5.1e-133 444.2 29.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EMC92680.1 - 3.3e-10 39.4 36.9 2.3e-07 30.1 7.2 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Cadherin_C_2 PF16492.5 EMC92680.1 - 0.03 15.1 0.4 0.14 12.9 0.0 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Aquarius_N PF16399.5 EMC92681.1 - 1.8e-293 975.6 0.0 2.1e-293 975.3 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EMC92681.1 - 6.7e-26 91.2 0.0 1.9e-25 89.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EMC92681.1 - 5.1e-25 88.8 0.0 3.9e-24 85.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMC92681.1 - 3.2e-09 36.8 0.6 0.0014 18.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EMC92681.1 - 2.6e-07 31.1 0.2 1.5e-06 28.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EMC92681.1 - 5.7e-05 23.2 0.0 0.00019 21.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 EMC92681.1 - 0.0002 21.1 0.1 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 EMC92681.1 - 0.0062 16.9 8.3 0.008 16.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 EMC92681.1 - 0.027 14.9 0.0 0.21 12.0 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EMC92681.1 - 0.06 12.9 0.0 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EMC92681.1 - 0.096 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase DnaB_C PF03796.15 EMC92681.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain UvrD-helicase PF00580.21 EMC92681.1 - 0.14 11.7 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_5 PF07728.14 EMC92681.1 - 0.15 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EMC92681.1 - 0.17 12.1 0.7 10 6.4 0.0 3.4 3 1 1 4 4 4 0 AAA domain Usp PF00582.26 EMC92682.1 - 1.7e-22 80.5 0.0 2.1e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family ABA_GPCR PF12430.8 EMC92683.1 - 1.8e-55 187.5 0.7 1.8e-55 187.5 0.7 2.1 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EMC92683.1 - 4.5e-24 84.3 0.2 6.6e-23 80.6 0.0 2.7 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF1501 PF07394.12 EMC92683.1 - 0.15 11.0 0.5 0.22 10.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) FAD_binding_3 PF01494.19 EMC92684.1 - 4.5e-22 78.8 0.4 2.1e-21 76.5 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC92684.1 - 1.6e-07 31.2 0.7 7.1e-06 25.8 0.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC92684.1 - 3.4e-05 24.0 0.5 8.4e-05 22.7 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EMC92684.1 - 0.00015 20.9 0.0 0.001 18.2 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 EMC92684.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EMC92684.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2007 PF09413.10 EMC92684.1 - 0.038 14.2 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Lycopene_cycl PF05834.12 EMC92684.1 - 0.038 13.0 0.8 2.1 7.3 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein TrkA_N PF02254.18 EMC92684.1 - 0.091 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 EMC92684.1 - 0.12 12.3 0.2 0.3 11.1 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EMC92684.1 - 0.14 10.8 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 EMC92684.1 - 0.14 11.8 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.18 EMC92685.1 - 3.3e-09 36.2 0.0 6.4e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC92685.1 - 0.065 13.4 1.9 0.16 12.1 1.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EMC92686.1 - 2.9e-29 101.9 1.7 8.4e-19 67.8 0.2 3.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC92686.1 - 1.5e-23 83.6 1.1 2.1e-14 53.7 0.0 2.9 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC92686.1 - 0.00022 21.2 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 KR domain WGG PF10273.9 EMC92687.1 - 9.1e-31 106.4 0.7 1.4e-30 105.8 0.7 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Phage_Gp17 PF17549.2 EMC92687.1 - 0.065 13.3 2.8 0.13 12.3 2.8 1.4 1 0 0 1 1 1 0 Gene Product 17 RRP7 PF12923.7 EMC92687.1 - 0.1 12.7 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain COPI_C PF06957.11 EMC92687.1 - 1.6 7.4 3.1 2 7.1 3.1 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EMC92688.1 - 3.7e-05 24.4 7.4 0.0041 17.9 0.0 6.1 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC92688.1 - 0.00035 20.8 0.2 41 4.6 0.0 5.7 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_N PF01194.17 EMC92689.1 - 3.5e-29 100.9 0.3 4.4e-29 100.6 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF1610 PF07754.11 EMC92689.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Acetyltransf_1 PF00583.25 EMC92690.1 - 3.4e-06 27.3 0.0 6.8e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC92690.1 - 3.9e-06 26.8 0.0 6.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC92690.1 - 9.1e-06 26.0 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC92690.1 - 0.014 15.5 0.0 0.046 13.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC92690.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein zf-PARP PF00645.18 EMC92692.1 - 6e-23 81.5 0.7 1.7e-22 80.0 0.7 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CHZ PF09649.10 EMC92693.1 - 0.11 12.0 0.9 0.11 12.0 0.9 2.0 2 0 0 2 2 2 0 Histone chaperone domain CHZ Abhydrolase_3 PF07859.13 EMC92694.1 - 8.3e-41 140.2 0.0 3.3e-40 138.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMC92694.1 - 2.3e-06 26.7 0.0 4.7e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Cation_efflux PF01545.21 EMC92695.1 - 1.1e-06 28.5 12.7 3.8e-06 26.8 12.9 1.6 1 1 1 2 2 2 1 Cation efflux family PIG-Y PF15159.6 EMC92696.1 - 1e-21 77.6 6.9 1.6e-21 77.0 6.9 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y MIF4G PF02854.19 EMC92697.1 - 4.1e-51 173.6 0.1 4.7e-51 173.4 0.1 1.0 1 0 0 1 1 1 1 MIF4G domain SPO22 PF08631.10 EMC92697.1 - 0.003 17.1 0.1 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like Neisseria_TspB PF05616.13 EMC92697.1 - 0.021 13.4 0.0 0.029 12.8 0.0 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF496 PF04363.12 EMC92697.1 - 0.031 14.3 0.2 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Eno-Rase_FAD_bd PF07055.12 EMC92697.1 - 0.061 13.7 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain DUF2097 PF09870.9 EMC92697.1 - 0.13 12.5 0.1 0.36 11.1 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) Homeodomain PF00046.29 EMC92698.1 - 2.3e-17 62.6 4.3 2.7e-17 62.4 3.0 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EMC92698.1 - 0.0049 16.7 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain efThoc1 PF11957.8 EMC92699.1 - 2.7e-119 399.1 0.0 3e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor NINJA_B PF16136.5 EMC92700.1 - 0.77 10.2 8.2 0.71 10.3 1.8 3.1 3 0 0 3 3 3 0 Putative nuclear localisation signal DUF2458 PF10454.9 EMC92702.1 - 3.2e-32 111.5 0.2 4.4e-32 111.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) COX14 PF14880.6 EMC92703.1 - 6.3e-13 48.4 0.1 1.8e-12 46.9 0.1 1.8 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Aminotran_5 PF00266.19 EMC92704.1 - 1.8e-09 37.0 0.0 3.2e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMC92704.1 - 0.013 14.8 0.7 0.016 14.5 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family ATG11 PF10377.9 EMC92705.1 - 2.9e-38 130.9 0.0 2.9e-38 130.9 0.0 3.8 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.12 EMC92705.1 - 1.4e-05 24.5 12.6 6.4e-05 22.2 7.6 5.8 2 2 2 4 4 4 3 Autophagy protein Apg17 TMF_TATA_bd PF12325.8 EMC92705.1 - 0.011 16.0 1.2 0.011 16.0 1.2 7.6 7 1 1 8 8 8 0 TATA element modulatory factor 1 TATA binding PGM_PMM_I PF02878.16 EMC92706.1 - 2.4e-33 114.8 0.1 3.6e-33 114.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EMC92706.1 - 2e-25 89.2 0.0 3.9e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EMC92706.1 - 2.3e-15 57.1 0.1 6.8e-15 55.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EMC92706.1 - 4.8e-08 33.1 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Fe-S_biosyn PF01521.20 EMC92707.1 - 8.5e-12 45.3 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pectinesterase PF01095.19 EMC92708.1 - 7.1e-21 74.2 0.8 1e-18 67.1 0.3 2.1 2 0 0 2 2 2 2 Pectinesterase DUF1996 PF09362.10 EMC92709.1 - 2e-57 194.9 0.1 2.3e-57 194.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NDT80_PhoG PF05224.12 EMC92710.1 - 1.6e-32 113.2 0.0 2.6e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.21 EMC92711.1 - 7.3e-63 212.8 0.0 9.6e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 EMC92711.1 - 0.00039 20.6 0.0 0.0033 17.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 EMC92711.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Amidohydro_1 PF01979.20 EMC92712.1 - 6.7e-14 51.9 0.0 8.5e-13 48.3 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMC92712.1 - 2.2e-11 43.9 0.0 8.7e-08 32.1 0.1 2.7 3 0 0 3 3 3 2 Amidohydrolase family ABC1 PF03109.16 EMC92713.1 - 6.1e-21 74.8 0.0 1.7e-11 44.3 0.0 2.4 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.22 EMC92713.1 - 0.0028 17.3 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Ten1 PF12658.7 EMC92713.1 - 0.065 13.2 0.0 12 5.9 0.0 2.3 1 1 1 2 2 2 0 Telomere capping, CST complex subunit Raf1_HTH PF18579.1 EMC92713.1 - 0.093 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain APH PF01636.23 EMC92713.1 - 0.11 12.3 0.2 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Reovirus_L2 PF06016.11 EMC92714.1 - 0.013 12.8 0.0 0.015 12.5 0.0 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) Tfb2 PF03849.14 EMC92716.1 - 7.4e-137 456.1 0.0 9e-137 455.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EMC92716.1 - 9.7e-16 58.0 0.4 1.9e-15 57.0 0.4 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EMC92716.1 - 0.00012 22.2 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HMG_CoA_synt_C PF08540.10 EMC92718.1 - 2.4e-106 355.4 0.4 3.1e-106 355.1 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EMC92718.1 - 1.8e-92 308.0 0.1 3.2e-92 307.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF4731 PF15875.5 EMC92719.1 - 0.047 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) dCMP_cyt_deam_1 PF00383.23 EMC92720.1 - 2.5e-26 91.5 0.0 3.5e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMC92720.1 - 1.8e-19 69.8 0.0 2.1e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EMC92720.1 - 0.00086 19.4 0.5 0.027 14.6 0.5 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 EMC92720.1 - 0.0011 19.1 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EMC92720.1 - 0.022 14.9 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 NAD1 PF18778.1 EMC92720.1 - 0.058 13.5 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 EMC92720.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 Pkinase PF00069.25 EMC92721.1 - 6.3e-51 173.3 0.0 1.5e-50 172.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92721.1 - 1.6e-23 83.3 0.3 3.1e-23 82.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EMC92721.1 - 0.0036 17.3 0.1 0.0036 17.3 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMC92721.1 - 0.0088 15.7 0.1 0.036 13.7 0.1 1.9 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EMC92721.1 - 0.23 11.0 1.0 0.42 10.2 0.2 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF1765 PF08578.10 EMC92722.1 - 1.1e-41 142.1 2.7 4.3e-41 140.3 2.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Coat_F PF07875.12 EMC92722.1 - 0.11 12.7 0.3 0.67 10.2 0.2 2.2 2 0 0 2 2 2 0 Coat F domain HlyIII PF03006.20 EMC92723.1 - 2.6e-64 217.0 9.4 3.4e-64 216.6 9.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF2235 PF09994.9 EMC92724.1 - 1.4e-77 260.9 0.0 1.8e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ndc80_HEC PF03801.13 EMC92725.1 - 8.2e-55 184.6 0.9 1.4e-54 183.8 0.1 1.8 2 0 0 2 2 2 1 HEC/Ndc80p family PHM7_cyt PF14703.6 EMC92725.1 - 0.016 15.4 5.8 0.52 10.5 0.0 3.6 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Spc7 PF08317.11 EMC92725.1 - 0.42 9.4 48.4 0.062 12.2 18.3 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 EMC92725.1 - 2.7 7.8 28.8 0.38 10.6 4.4 3.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF812 PF05667.11 EMC92725.1 - 5.6 5.7 37.1 1.6 7.6 19.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) FAT PF02259.23 EMC92726.1 - 8.7e-126 419.8 0.2 1.8e-125 418.7 0.2 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EMC92726.1 - 2.6e-74 250.2 0.1 5.8e-74 249.1 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EMC92726.1 - 8.9e-64 214.3 9.2 4.2e-60 202.3 0.1 5.9 5 2 1 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EMC92726.1 - 4.3e-44 148.9 5.1 1.2e-42 144.4 0.0 4.2 3 1 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EMC92726.1 - 4.6e-14 52.6 15.2 0.0033 17.8 0.1 9.3 8 1 1 9 9 9 4 HEAT repeats FATC PF02260.20 EMC92726.1 - 4.8e-14 51.9 0.2 2.3e-13 49.7 0.1 2.3 2 0 0 2 2 2 1 FATC domain Cnd1 PF12717.7 EMC92726.1 - 7.7e-10 39.1 3.7 0.011 15.8 0.1 6.6 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EMC92726.1 - 1.5e-09 37.3 18.4 1.6 9.2 0.0 12.3 13 0 0 13 13 13 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EMC92726.1 - 6.1e-06 26.8 5.7 6.6 7.4 0.0 7.7 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EMC92726.1 - 8.1e-05 22.3 5.1 0.37 10.3 0.0 4.5 4 1 2 6 6 6 2 CLASP N terminal Adaptin_N PF01602.20 EMC92726.1 - 0.00021 20.0 7.8 0.1 11.2 0.0 5.2 5 1 1 6 6 6 2 Adaptin N terminal region HEAT_EZ PF13513.6 EMC92726.1 - 0.00021 21.7 19.5 0.77 10.3 0.1 10.2 11 1 1 12 12 10 2 HEAT-like repeat ParcG PF10274.9 EMC92726.1 - 0.0021 18.2 8.5 0.23 11.6 0.1 5.2 5 0 0 5 5 5 1 Parkin co-regulated protein Mad3_BUB1_I PF08311.12 EMC92726.1 - 0.059 13.3 0.2 0.22 11.5 0.2 1.9 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 TPR_19 PF14559.6 EMC92726.1 - 0.18 12.3 1.1 4.7 7.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RICTOR_N PF14664.6 EMC92726.1 - 0.19 10.6 1.6 7.4 5.4 0.1 3.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term Peptidase_S24 PF00717.23 EMC92727.1 - 1.2e-07 31.6 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF1768 PF08719.11 EMC92728.1 - 7.6e-55 185.6 0.4 8.6e-55 185.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) FCH PF00611.23 EMC92729.1 - 1.7e-15 57.0 0.0 1.3e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Flavodoxin_3 PF12641.7 EMC92729.1 - 0.12 12.0 1.1 5.6 6.6 1.0 2.4 2 0 0 2 2 2 0 Flavodoxin domain Vps5 PF09325.10 EMC92729.1 - 0.48 9.9 5.8 0.96 8.9 1.5 2.5 2 0 0 2 2 2 0 Vps5 C terminal like IBR PF01485.21 EMC92730.1 - 1.8e-19 69.7 28.2 2.2e-10 40.6 7.0 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EMC92730.1 - 0.85 9.7 19.3 0.8 9.8 0.3 3.7 3 1 0 3 3 3 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EMC92730.1 - 2.7 7.9 30.5 0.091 12.7 2.9 4.0 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Cg6151-P PF10233.9 EMC92731.1 - 3.3e-42 143.3 17.9 4e-42 143.1 17.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.13 EMC92731.1 - 0.11 12.0 5.5 0.078 12.5 1.1 2.2 2 1 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Dpy19 PF10034.9 EMC92731.1 - 0.78 7.9 10.9 0.94 7.6 10.9 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF2721 PF11026.8 EMC92731.1 - 7.8 6.4 17.7 2.3 8.1 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) IBN_N PF03810.19 EMC92732.1 - 3.4e-14 52.5 0.0 4.7e-12 45.7 0.0 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 EMC92732.1 - 4.9e-05 22.3 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Cse1 Sigma70_ner PF04546.13 EMC92732.1 - 0.0052 16.7 2.0 0.013 15.3 2.0 1.7 1 0 0 1 1 1 1 Sigma-70, non-essential region RTP1_C1 PF10363.9 EMC92732.1 - 0.048 13.8 0.7 0.7 10.1 0.2 2.9 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 EMC92732.1 - 0.6 10.2 5.0 1.1 9.4 0.1 3.8 5 1 0 5 5 5 0 Exportin 1-like protein SDA1 PF05285.12 EMC92732.1 - 3.4 7.0 8.5 5.2 6.4 8.5 1.2 1 0 0 1 1 1 0 SDA1 HEAT_EZ PF13513.6 EMC92732.1 - 6.3 7.4 7.5 23 5.6 0.5 4.9 5 0 0 5 5 5 0 HEAT-like repeat MFS_1 PF07690.16 EMC92733.1 - 1.5e-21 76.7 50.9 3.7e-20 72.2 40.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC92733.1 - 3e-09 36.2 2.6 3e-09 36.2 2.6 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Vps35 PF03635.17 EMC92735.1 - 0 1017.3 0.1 0 1017.1 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Swi3 PF07962.12 EMC92737.1 - 1.3e-30 105.2 0.3 2e-30 104.6 0.3 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 MRC1 PF09444.10 EMC92737.1 - 0.16 12.5 7.6 0.037 14.5 4.0 1.8 2 0 0 2 2 2 0 MRC1-like domain Pkinase PF00069.25 EMC92738.1 - 4e-67 226.4 0.0 5.2e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92738.1 - 2e-31 109.2 0.0 2.8e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMC92738.1 - 0.0082 15.1 0.3 0.012 14.6 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EMC92738.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Glyco_hydro_47 PF01532.20 EMC92739.1 - 2.5e-135 451.9 0.0 2.9e-135 451.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fungal_trans PF04082.18 EMC92740.1 - 0.00017 20.7 0.1 0.00033 19.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain YfcL PF08891.11 EMC92740.1 - 0.0054 17.0 0.4 0.026 14.9 0.1 2.2 2 0 0 2 2 2 1 YfcL protein HTH_32 PF13565.6 EMC92741.1 - 5e-07 30.2 0.8 0.0056 17.3 0.0 2.8 2 1 1 3 3 3 2 Homeodomain-like domain HTH_7 PF02796.15 EMC92741.1 - 5.3e-05 23.2 0.0 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EMC92741.1 - 0.11 12.3 0.1 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain PAX PF00292.18 EMC92741.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain Trp_repressor PF01371.19 EMC92741.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein DHquinase_II PF01220.19 EMC92743.1 - 4.5e-62 207.8 0.0 5.1e-62 207.6 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Dioxygenase_C PF00775.21 EMC92744.1 - 1.7e-39 135.1 0.0 2.3e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EMC92744.1 - 3.4e-31 106.9 0.0 5.9e-31 106.1 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus GP120 PF00516.18 EMC92746.1 - 0.13 10.9 0.9 0.17 10.4 0.5 1.3 1 1 0 1 1 1 0 Envelope glycoprotein GP120 SnoaL_4 PF13577.6 EMC92747.1 - 1.7e-06 28.2 0.3 2.8e-06 27.5 0.3 1.4 1 0 0 1 1 1 1 SnoaL-like domain Ras PF00071.22 EMC92748.1 - 1.5e-49 167.7 0.0 9.5e-48 161.9 0.0 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EMC92748.1 - 2.1e-21 76.4 0.0 1.7e-19 70.2 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Shikimate_dh_N PF08501.11 EMC92748.1 - 3.9e-17 62.3 0.0 8.4e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 EMC92748.1 - 9.3e-16 58.8 0.0 1.6e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EMC92748.1 - 7.5e-11 42.4 0.0 1.5e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 EMC92748.1 - 7.7e-07 28.8 0.2 1.6e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EMC92748.1 - 2.6e-06 27.6 0.0 1e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Arf PF00025.21 EMC92748.1 - 3.1e-05 23.5 0.0 5.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 EMC92748.1 - 0.00064 20.1 0.0 0.48 10.8 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMC92748.1 - 0.064 13.1 0.1 0.59 10.0 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 EMC92748.1 - 0.097 13.2 0.0 18 5.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 EMC92748.1 - 0.12 12.4 0.0 9 6.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EMC92748.1 - 0.13 11.6 0.1 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMC92748.1 - 0.22 10.9 0.0 0.81 9.1 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NST1 PF13945.6 EMC92750.1 - 2e-50 171.6 3.4 2e-50 171.6 3.4 5.3 3 2 2 5 5 5 1 Salt tolerance down-regulator ADH_zinc_N PF00107.26 EMC92751.1 - 1.2e-16 60.9 0.0 3e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC92751.1 - 0.15 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Abhydrolase_1 PF00561.20 EMC92756.1 - 6.8e-16 58.7 0.2 3.9e-15 56.2 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC92756.1 - 9.4e-15 55.8 5.7 1.3e-14 55.4 5.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 EMC92756.1 - 0.064 13.6 0.1 0.064 13.6 0.1 1.8 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Mgm101p PF06420.12 EMC92757.1 - 7.5e-84 279.4 0.0 9.8e-84 279.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.9 EMC92758.1 - 2.5e-146 487.6 0.0 3.3e-146 487.2 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EMC92758.1 - 1e-20 74.0 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pex24p PF06398.11 EMC92759.1 - 4e-85 286.0 0.5 5.2e-85 285.6 0.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pam16 PF03656.13 EMC92760.1 - 5.5e-35 120.2 0.9 6.6e-35 119.9 0.9 1.0 1 0 0 1 1 1 1 Pam16 HA2 PF04408.23 EMC92762.1 - 4.7e-16 59.0 0.0 1.6e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMC92762.1 - 6.3e-16 58.7 0.0 1.7e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMC92762.1 - 2.1e-11 44.0 0.0 6.3e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EMC92762.1 - 3.5e-07 30.2 0.0 8.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EMC92762.1 - 0.00017 21.9 0.0 0.01 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain dsrm PF00035.26 EMC92762.1 - 0.00034 21.2 1.1 0.089 13.5 0.0 3.7 3 0 0 3 3 3 1 Double-stranded RNA binding motif FtsK_SpoIIIE PF01580.18 EMC92762.1 - 0.001 18.4 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 EMC92762.1 - 0.057 13.7 0.0 0.27 11.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMC92762.1 - 0.095 13.2 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain BCS1_N PF08740.11 EMC92763.1 - 4.5e-41 140.9 0.3 7.1e-41 140.2 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EMC92763.1 - 4.1e-19 69.3 0.0 7.7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMC92763.1 - 5.9e-05 23.1 0.0 0.00016 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC92763.1 - 0.00029 21.3 0.0 0.00095 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EMC92763.1 - 0.0054 16.9 0.0 0.019 15.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EMC92763.1 - 0.0059 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 EMC92763.1 - 0.0081 15.8 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EMC92763.1 - 0.0082 15.3 0.0 0.015 14.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) ATPase PF06745.13 EMC92763.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.12 EMC92763.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EMC92763.1 - 0.028 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMC92763.1 - 0.032 14.8 0.0 0.075 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMC92763.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EMC92763.1 - 0.073 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EMC92763.1 - 0.074 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EMC92763.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 EMC92763.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EMC92763.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 EMC92763.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_17 PF13207.6 EMC92763.1 - 0.15 12.5 0.2 4.4 7.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF2922 PF11148.8 EMC92764.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) PRTP PF01366.18 EMC92765.1 - 0.46 8.5 1.6 0.54 8.2 1.6 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Dak2 PF02734.17 EMC92767.1 - 0.13 12.1 2.3 0.36 10.7 2.3 1.7 1 0 0 1 1 1 0 DAK2 domain P16-Arc PF04699.14 EMC92768.1 - 2.4e-48 164.4 0.0 2.8e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UQ_con PF00179.26 EMC92769.1 - 5.2e-19 68.3 0.0 7.9e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PDH PF02153.17 EMC92770.1 - 7.7e-15 54.6 0.0 1.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 EMC92770.1 - 1.2e-06 29.0 0.1 4.9e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EMC92770.1 - 4.4e-06 26.9 0.1 8.5e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EMC92770.1 - 0.00041 19.8 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMC92770.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EMC92770.1 - 0.0027 17.3 0.0 0.0062 16.2 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EMC92770.1 - 0.018 15.3 0.0 0.045 14.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.9 EMC92770.1 - 0.11 12.4 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Rossmann-like domain CFEM PF05730.11 EMC92772.1 - 3.1e-10 40.0 7.4 6.1e-10 39.1 7.4 1.5 1 0 0 1 1 1 1 CFEM domain p450 PF00067.22 EMC92773.1 - 1.2e-66 225.4 0.1 2e-66 224.7 0.0 1.3 2 0 0 2 2 2 1 Cytochrome P450 Lactamase_B_2 PF12706.7 EMC92774.1 - 6.5e-31 107.4 0.1 2.1e-29 102.5 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMC92774.1 - 1.2e-10 41.5 0.0 2.6e-10 40.5 0.0 1.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMC92774.1 - 0.00069 19.7 1.2 0.016 15.2 0.5 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Colicin_Pyocin PF01320.18 EMC92775.1 - 0.47 10.6 2.2 51 4.1 0.1 3.0 3 0 0 3 3 3 0 Colicin immunity protein / pyocin immunity protein Thiolase_N PF00108.23 EMC92778.1 - 6e-79 265.1 0.3 8e-79 264.6 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMC92778.1 - 6.9e-44 148.4 0.4 2.2e-43 146.8 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMC92778.1 - 0.00078 19.1 0.5 0.003 17.2 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Polysacc_deac_2 PF04748.13 EMC92778.1 - 0.13 11.4 0.0 0.33 10.1 0.0 1.7 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF3245 PF11595.8 EMC92779.1 - 1.1e-15 58.4 9.8 1.1e-15 58.4 9.8 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) CBFD_NFYB_HMF PF00808.23 EMC92780.1 - 4.4e-14 52.5 5.2 1.4e-12 47.7 5.2 2.2 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 EMC92780.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.5 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 EMC92780.1 - 0.0054 17.1 0.2 0.013 15.9 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 EF-hand_14 PF17959.1 EMC92780.1 - 0.094 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain Mid2 PF04478.12 EMC92781.1 - 0.01 15.7 0.1 0.01 15.7 0.1 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 EMC92781.1 - 0.016 14.6 0.1 0.054 12.9 0.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Acetyltransf_1 PF00583.25 EMC92782.1 - 9.7e-14 51.6 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC92782.1 - 4.4e-13 49.3 0.0 1.2e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC92782.1 - 8e-12 45.4 0.0 1.8e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC92782.1 - 1.5e-10 41.2 0.0 6.4e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC92782.1 - 1.4e-06 28.2 0.1 2.6e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EMC92782.1 - 0.034 14.3 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 EMC92782.1 - 0.039 13.9 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Fungal_trans PF04082.18 EMC92783.1 - 1.1e-08 34.5 0.1 2e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC92783.1 - 2e-06 27.8 6.6 3.2e-06 27.1 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5329 PF17263.2 EMC92783.1 - 0.021 15.0 0.2 0.065 13.4 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5329) TFR_dimer PF04253.15 EMC92784.1 - 1.6e-26 92.8 0.0 3.8e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EMC92784.1 - 4.1e-12 46.2 0.0 9.6e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EMC92784.1 - 1.6e-08 34.4 0.0 4.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 PA domain GFO_IDH_MocA PF01408.22 EMC92785.1 - 1.9e-12 48.0 0.0 4.4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMC92785.1 - 0.0002 21.3 0.0 0.00079 19.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain HTH_psq PF05225.16 EMC92785.1 - 0.017 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain GARS_N PF02844.15 EMC92785.1 - 0.19 12.5 0.0 30 5.5 0.0 3.2 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain Cyto_heme_lyase PF01265.17 EMC92786.1 - 9.4e-123 409.4 0.3 1.1e-122 409.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Ribonucleas_3_3 PF14622.6 EMC92787.1 - 1.3e-07 31.8 0.0 1.8e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EMC92787.1 - 6.9e-05 23.4 0.0 0.00022 21.8 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Aim21 PF11489.8 EMC92790.1 - 2e-153 513.0 69.5 3.3e-150 502.4 69.5 2.2 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 21 Inositol_P PF00459.25 EMC92793.1 - 4.2e-72 242.9 0.0 4.8e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family HSF_DNA-bind PF00447.17 EMC92794.1 - 8.1e-27 93.7 0.3 3.1e-26 91.8 0.3 1.9 1 1 0 1 1 1 1 HSF-type DNA-binding Sugar_tr PF00083.24 EMC92795.1 - 5.2e-66 223.4 9.4 5.8e-66 223.2 9.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC92795.1 - 1e-08 34.5 23.8 1.6e-06 27.3 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMC92795.1 - 0.00093 17.9 11.4 0.00093 17.9 11.4 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein EMP70 PF02990.16 EMC92795.1 - 0.063 11.9 9.2 0.022 13.4 6.5 1.5 1 1 1 2 2 2 0 Endomembrane protein 70 Pex14_N PF04695.13 EMC92796.1 - 1.3e-38 133.1 0.6 1.3e-38 133.1 0.6 3.1 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GrpE PF01025.19 EMC92796.1 - 0.02 14.5 6.8 0.034 13.8 6.8 1.3 1 0 0 1 1 1 0 GrpE UPF0242 PF06785.11 EMC92796.1 - 0.039 14.0 2.9 0.072 13.2 2.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Halogen_Hydrol PF10112.9 EMC92796.1 - 0.066 13.2 0.1 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Jnk-SapK_ap_N PF09744.9 EMC92796.1 - 0.076 13.2 8.3 0.16 12.2 8.3 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HTH_IclR PF09339.10 EMC92796.1 - 0.18 11.6 0.8 0.49 10.2 0.1 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain LMBR1 PF04791.16 EMC92796.1 - 0.24 10.3 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CLZ PF16526.5 EMC92796.1 - 0.36 11.2 7.6 0.67 10.3 0.7 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4208 PF13907.6 EMC92796.1 - 0.44 11.0 2.8 0.87 10.1 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) AAA_lid_9 PF17871.1 EMC92796.1 - 0.86 9.6 6.7 0.61 10.0 3.6 2.2 1 1 1 2 2 2 0 AAA lid domain zf-C4H2 PF10146.9 EMC92796.1 - 1.6 9.0 11.4 0.21 11.9 1.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Surp PF01805.20 EMC92797.1 - 8.5e-07 28.9 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Surp module Pkinase PF00069.25 EMC92798.1 - 2.6e-62 210.6 0.0 3.5e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92798.1 - 1.5e-28 99.8 0.0 2.2e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMC92798.1 - 5.6e-05 22.6 0.1 9.8e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMC92798.1 - 0.0031 16.5 0.0 0.005 15.8 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EMC92798.1 - 0.038 13.3 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EMC92798.1 - 0.045 13.3 0.0 0.045 13.3 0.0 1.5 2 0 0 2 2 2 0 RIO1 family FHIPEP PF00771.20 EMC92798.1 - 0.081 11.4 0.4 0.13 10.7 0.4 1.3 1 1 0 1 1 1 0 FHIPEP family Casc1_N PF15927.5 EMC92798.1 - 0.087 12.5 9.1 0.17 11.6 9.1 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus APH PF01636.23 EMC92798.1 - 0.096 12.6 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_28 PF02636.17 EMC92799.1 - 2.1e-76 257.0 0.0 2.7e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Myb_DNA-bind_6 PF13921.6 EMC92799.1 - 3.5e-05 24.0 0.9 9.8e-05 22.5 0.3 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMC92799.1 - 6.4e-05 23.1 1.4 8.7e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain adh_short PF00106.25 EMC92800.1 - 1.8e-32 112.4 0.0 2.5e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC92800.1 - 2.9e-23 82.7 0.0 3.9e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC92800.1 - 4.6e-07 29.9 0.0 2.4e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 KR domain HAT PF02184.16 EMC92800.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat Peptidase_C12 PF01088.21 EMC92801.1 - 1.7e-47 161.9 0.0 1.9e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Complex1_LYR PF05347.15 EMC92804.1 - 0.0021 18.1 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Herpes_UL17 PF04559.12 EMC92804.1 - 0.027 13.3 0.4 0.034 13.0 0.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein RAC_head PF16717.5 EMC92805.1 - 2.8e-31 108.4 3.4 2.8e-31 108.4 3.4 3.8 3 1 1 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 EMC92805.1 - 2.5e-19 69.2 0.3 1.3e-18 66.9 0.3 2.4 1 0 0 1 1 1 1 DnaJ domain V_ATPase_I PF01496.19 EMC92805.1 - 2.1 6.2 12.1 3.4 5.5 12.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Yip1 PF04893.17 EMC92808.1 - 3.2e-06 27.0 16.7 2.2e-05 24.2 16.7 2.2 1 1 0 1 1 1 1 Yip1 domain HRI1 PF16815.5 EMC92810.1 - 5.6e-68 229.1 1.6 6.3e-68 228.9 1.6 1.0 1 0 0 1 1 1 1 Protein HRI1 HET PF06985.11 EMC92811.1 - 1e-34 120.0 3.7 1.2e-34 119.8 3.7 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cadherin_C PF01049.17 EMC92811.1 - 0.058 13.7 0.0 0.065 13.6 0.0 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic region Bac_surface_Ag PF01103.23 EMC92812.1 - 1.1e-43 150.0 0.1 1.4e-43 149.6 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Peripla_BP_2 PF01497.18 EMC92812.1 - 0.035 13.7 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Glyco_hydro_1 PF00232.18 EMC92813.1 - 1.2e-105 353.6 3.6 1.8e-105 353.0 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 CBM_10 PF02013.16 EMC92813.1 - 0.77 10.3 2.6 1.3 9.5 0.6 2.2 2 0 0 2 2 2 0 Cellulose or protein binding domain AMP-binding PF00501.28 EMC92814.1 - 1.3e-65 221.7 0.0 3.1e-65 220.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EMC92814.1 - 7.3e-64 215.4 0.0 1.1e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EMC92814.1 - 1.4e-09 38.2 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EMC92814.1 - 1.1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMC92814.1 - 7.9e-07 28.4 0.0 1.9e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMC92814.1 - 9.7e-06 25.6 0.0 0.0001 22.3 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding AMP-binding_C PF13193.6 EMC92814.1 - 0.0079 17.1 0.0 0.78 10.8 0.0 3.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 EMC92814.1 - 0.034 13.3 0.0 1.2 8.2 0.0 2.6 3 0 0 3 3 3 0 RmlD substrate binding domain IBR PF01485.21 EMC92815.1 - 1.9e-14 53.6 45.0 5.5e-08 32.9 12.2 3.4 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-CCHC PF00098.23 EMC92815.1 - 0.00072 19.5 3.3 0.00072 19.5 3.3 3.8 4 0 0 4 4 4 1 Zinc knuckle zf-RING_4 PF14570.6 EMC92815.1 - 0.44 10.4 34.7 0.071 12.9 3.5 4.0 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain Cyt-b5 PF00173.28 EMC92817.1 - 2.5e-12 46.7 0.0 3.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myotoxins PF00819.17 EMC92818.1 - 0.014 15.7 1.3 0.043 14.1 0.1 2.1 2 0 0 2 2 2 0 Myotoxin, crotamine RRM_1 PF00076.22 EMC92821.1 - 1.3e-07 31.3 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMC92821.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.10 EMC92822.1 - 4.1e-30 103.9 0.4 6.9e-30 103.2 0.4 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EMC92822.1 - 1.1e-20 74.1 0.0 1.9e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC92822.1 - 1.7e-18 67.1 0.0 3.1e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC92822.1 - 4.1e-18 65.6 0.0 6.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMC92822.1 - 1.9e-13 50.3 0.0 3.4e-13 49.5 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EMC92822.1 - 1.3e-11 44.6 0.0 2.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC92822.1 - 3.6e-10 39.6 0.0 5.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMC92822.1 - 1.1e-08 35.7 0.0 3.2e-08 34.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.19 EMC92822.1 - 1.6e-05 24.8 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 EMC92822.1 - 1.9e-05 23.5 0.0 2.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 EMC92822.1 - 0.0002 20.9 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EMC92822.1 - 0.0079 15.8 0.0 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EMC92822.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 EMC92822.1 - 0.022 14.8 0.1 0.052 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 EMC92822.1 - 0.048 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 EMC92822.1 - 0.056 12.7 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain UPF0020 PF01170.18 EMC92822.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 EMC92822.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pterin_4a PF01329.19 EMC92823.1 - 3.1e-26 91.4 1.4 3.7e-26 91.1 1.4 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase BKACE PF05853.12 EMC92823.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme DUF3016 PF11454.8 EMC92824.1 - 0.14 11.9 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) NYN PF01936.18 EMC92825.1 - 7.4e-07 29.7 0.0 1.1e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 EMC92825.1 - 0.0082 15.9 0.0 0.025 14.4 0.0 1.8 2 0 0 2 2 2 1 OST-HTH/LOTUS domain Transket_pyr PF02779.24 EMC92826.1 - 7.5e-49 165.8 0.0 1.3e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMC92826.1 - 6.1e-35 119.8 0.1 2.3e-34 118.0 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DNA_pol_B PF00136.21 EMC92827.1 - 3.4e-114 382.1 0.5 5.1e-114 381.5 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EMC92827.1 - 2.5e-61 206.7 0.0 5.4e-61 205.6 0.0 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EMC92827.1 - 1.1e-41 143.1 0.0 2.7e-41 141.9 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EMC92827.1 - 5.9e-24 83.9 7.6 5.9e-24 83.9 7.6 3.4 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal VWA_N2 PF16164.5 EMC92827.1 - 0.0095 16.1 0.2 0.025 14.7 0.2 1.7 1 0 0 1 1 1 1 VWA N-terminal DNA_pol_B_2 PF03175.13 EMC92827.1 - 0.02 13.8 0.1 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral Tnp_DNA_bind PF14706.6 EMC92827.1 - 0.094 12.6 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Transposase DNA-binding DUF1744 PF08490.12 EMC92827.1 - 0.098 11.2 0.4 0.19 10.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1744) NTP_transf_9 PF04248.12 EMC92828.1 - 1.6e-32 111.2 0.1 2.2e-32 110.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Oxidored_FMN PF00724.20 EMC92829.1 - 7.3e-80 268.8 0.0 8.3e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.24 EMC92830.1 - 4.7e-16 58.7 13.4 7.6e-10 38.2 11.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter EbsA PF17255.2 EMC92830.1 - 0.31 11.4 2.1 0.84 10.0 2.2 1.6 2 0 0 2 2 2 0 EbsA-like protein alpha-hel2 PF14456.6 EMC92831.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 adh_short_C2 PF13561.6 EMC92833.1 - 4.8e-49 167.0 4.2 3.5e-41 141.3 1.8 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC92833.1 - 1.3e-45 155.3 1.4 1.7e-45 154.9 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC92833.1 - 3.8e-14 53.0 0.2 5.4e-14 52.5 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMC92833.1 - 0.00072 19.5 0.5 0.0012 18.8 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EMC92833.1 - 0.0043 16.4 0.1 0.0073 15.6 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 EMC92833.1 - 0.0071 16.4 0.3 0.013 15.6 0.3 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMC92833.1 - 0.068 12.7 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Arginosuc_synth PF00764.19 EMC92834.1 - 2.7e-157 524.1 0.0 3.1e-157 523.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EMC92834.1 - 0.019 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EMC92834.1 - 0.057 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase MARVEL PF01284.23 EMC92835.1 - 0.0072 16.4 8.4 0.012 15.6 8.4 1.4 1 1 0 1 1 1 1 Membrane-associating domain Ish1 PF10281.9 EMC92836.1 - 1.1e-59 198.4 17.6 1.2e-13 51.1 0.1 5.4 5 0 0 5 5 5 5 Putative stress-responsive nuclear envelope protein HeH PF12949.7 EMC92836.1 - 1.3e-07 31.2 0.0 0.085 12.6 0.0 4.2 4 0 0 4 4 4 3 HeH/LEM domain SAP PF02037.27 EMC92836.1 - 3.3e-05 23.5 0.0 0.28 11.0 0.0 3.8 3 0 0 3 3 3 1 SAP domain Slx4 PF09494.10 EMC92836.1 - 0.0002 21.2 1.0 0.37 10.8 0.1 3.3 4 0 0 4 4 4 2 Slx4 endonuclease TryThrA_C PF12319.8 EMC92836.1 - 0.38 10.2 19.2 1.4 8.4 9.3 3.4 1 1 2 3 3 3 0 Tryptophan-Threonine-rich plasmodium antigen C terminal ApoLp-III PF07464.11 EMC92836.1 - 3.2 7.9 7.4 1.7 8.7 0.5 3.1 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Actin PF00022.19 EMC92837.1 - 3.5e-27 95.1 0.0 9e-14 50.9 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EMC92837.1 - 2.2e-05 23.4 0.0 4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Actin_micro PF17003.5 EMC92837.1 - 0.00084 18.6 0.1 0.031 13.5 0.1 2.1 2 0 0 2 2 2 1 Putative actin-like family FtsA PF14450.6 EMC92837.1 - 0.021 15.3 0.0 0.068 13.6 0.0 1.9 3 0 0 3 3 3 0 Cell division protein FtsA NTF2 PF02136.20 EMC92839.1 - 5.2e-31 107.7 0.4 5.8e-31 107.6 0.4 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 EMC92839.1 - 0.08 13.3 0.0 0.09 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) RNA_pol_3_Rpc31 PF11705.8 EMC92840.1 - 1.9e-31 110.1 15.7 2.4e-31 109.8 15.7 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Tub_N PF16322.5 EMC92840.1 - 0.2 12.0 4.0 0.31 11.4 4.0 1.3 1 1 0 1 1 1 0 Tubby N-terminal PPP4R2 PF09184.11 EMC92840.1 - 2 8.0 9.5 2.4 7.7 9.5 1.2 1 0 0 1 1 1 0 PPP4R2 Epimerase PF01370.21 EMC92843.1 - 1.6e-18 67.0 0.0 2.2e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC92843.1 - 1.2e-10 41.3 0.3 5.6e-10 39.1 0.1 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMC92843.1 - 2.1e-10 40.1 0.0 3.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMC92843.1 - 7.4e-10 38.4 0.1 2.3e-08 33.5 0.0 2.6 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EMC92843.1 - 2.9e-05 24.1 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMC92843.1 - 0.00042 20.3 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMC92843.1 - 0.0016 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EMC92843.1 - 0.0025 17.4 0.1 0.022 14.3 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EMC92843.1 - 0.0065 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EMC92843.1 - 0.018 14.2 0.0 0.054 12.6 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 EMC92843.1 - 0.17 12.0 0.3 0.38 10.9 0.3 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Arf PF00025.21 EMC92844.1 - 4.5e-73 244.4 0.0 5e-73 244.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMC92844.1 - 1.3e-13 51.2 0.0 1.8e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMC92844.1 - 1.6e-11 44.0 0.0 1.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EMC92844.1 - 1.3e-10 41.1 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EMC92844.1 - 8.4e-10 38.3 0.2 5.2e-06 25.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EMC92844.1 - 1.7e-08 34.1 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMC92844.1 - 5e-06 26.6 0.0 8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMC92844.1 - 0.0057 16.2 0.0 0.3 10.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EMC92844.1 - 0.026 14.0 0.6 0.079 12.5 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 EMC92844.1 - 0.07 13.7 0.1 0.12 13.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF2892 PF11127.8 EMC92848.1 - 0.21 11.7 0.2 0.21 11.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) adh_short_C2 PF13561.6 EMC92849.1 - 6.2e-53 179.8 0.0 7.1e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC92849.1 - 1.8e-46 158.1 0.0 2.3e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC92849.1 - 1.2e-08 35.0 0.0 2.3e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC92849.1 - 1e-06 28.4 0.0 2e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMC92849.1 - 2.2e-05 24.0 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EMC92849.1 - 0.031 13.7 0.2 0.059 12.8 0.1 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EMC92849.1 - 0.037 13.9 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EMC92849.1 - 0.063 12.4 0.0 0.27 10.3 0.0 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain FMN_dh PF01070.18 EMC92850.1 - 1.7e-120 402.2 0.0 2.1e-120 401.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EMC92850.1 - 3.4e-22 78.4 0.0 6.5e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EMC92850.1 - 6.7e-08 32.1 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EMC92850.1 - 7.8e-05 21.8 0.3 0.00046 19.3 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMC92850.1 - 0.011 15.1 0.2 0.02 14.3 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 EMC92850.1 - 0.023 14.2 0.8 0.6 9.5 0.1 2.4 1 1 1 2 2 2 0 Histidine biosynthesis protein Cytotoxic PF09000.10 EMC92850.1 - 0.15 12.4 0.1 0.39 11.1 0.1 1.7 1 0 0 1 1 1 0 Cytotoxic G3P_antiterm PF04309.12 EMC92850.1 - 0.17 11.3 0.0 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator FGGY_C PF02782.16 EMC92851.1 - 2.1e-50 171.2 0.2 3.4e-50 170.5 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EMC92851.1 - 2.6e-23 82.8 0.4 2.1e-19 70.1 0.0 3.0 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EMC92851.1 - 0.00022 20.8 0.1 0.0016 18.0 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Acetyltransf_3 PF13302.7 EMC92853.1 - 1.8e-05 25.4 0.1 2e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC92853.1 - 0.0036 17.5 0.0 0.0047 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC92853.1 - 0.092 13.2 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GFO_IDH_MocA PF01408.22 EMC92855.1 - 6.8e-18 65.6 0.1 9.6e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold FAD_binding_3 PF01494.19 EMC92856.1 - 1.6e-20 73.7 0.0 2.2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EMC92856.1 - 9.4e-05 21.6 0.0 0.00022 20.4 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 EMC92856.1 - 0.0071 16.3 2.1 0.49 10.4 0.3 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EMC92856.1 - 0.014 15.0 3.0 0.95 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC92856.1 - 0.13 12.5 1.6 0.36 11.1 0.5 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC92856.1 - 3.5 6.8 5.0 27 3.8 2.1 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADC PF06314.11 EMC92857.1 - 0.00095 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) adh_short_C2 PF13561.6 EMC92858.1 - 4.8e-47 160.5 0.0 6.6e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC92858.1 - 1.1e-40 139.2 0.0 1.4e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC92858.1 - 9.9e-12 45.1 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC92858.1 - 0.0012 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EMC92858.1 - 0.017 15.3 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ferritin_2 PF13668.6 EMC92860.1 - 5e-12 46.2 0.0 8.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DAGK_cat PF00781.24 EMC92861.1 - 6.3e-14 51.7 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Glyco_hydro_5_C PF18564.1 EMC92861.1 - 0.14 12.7 0.0 2.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Glycoside hydrolase family 5 C-terminal domain FeoB_associated PF12669.7 EMC92862.1 - 0.18 12.2 1.9 0.34 11.3 1.9 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein XPG_I_2 PF12813.7 EMC92863.1 - 1.2e-32 113.3 0.0 1.8e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing DUF1691 PF07950.11 EMC92864.1 - 4e-35 120.8 6.6 4.6e-31 107.7 4.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.8 EMC92865.1 - 4.9e-05 23.5 1.1 4.9e-05 23.5 1.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC92865.1 - 0.0012 19.2 2.3 0.0064 16.8 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 EMC92865.1 - 0.11 12.6 2.7 0.19 11.8 2.7 1.3 1 0 0 1 1 1 0 DBF zinc finger TANGO2 PF05742.12 EMC92866.1 - 5.2e-67 226.5 0.0 5.9e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 TB2_DP1_HVA22 PF03134.19 EMC92867.1 - 1.3e-21 76.3 7.5 1.9e-21 75.8 7.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF5542 PF17696.1 EMC92867.1 - 0.23 11.6 2.5 0.65 10.2 2.5 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DUF4078 PF13300.6 EMC92868.1 - 5.4e-29 100.3 17.0 5.4e-29 100.3 17.0 3.0 5 0 0 5 5 5 1 Domain of unknown function (DUF4078) Homoserine_dh PF00742.19 EMC92869.1 - 2.3e-52 177.4 0.0 5.4e-52 176.2 0.0 1.5 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EMC92869.1 - 1.9e-15 57.5 0.0 3.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain RSN1_7TM PF02714.15 EMC92870.1 - 1e-68 231.6 16.3 1e-68 231.6 16.3 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EMC92870.1 - 3.2e-43 148.0 0.4 4.6e-43 147.5 0.4 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EMC92870.1 - 1.5e-39 135.3 2.7 1.5e-39 135.3 2.7 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport CALCOCO1 PF07888.11 EMC92870.1 - 0.0017 17.3 2.3 0.0024 16.8 2.3 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like SNARE_assoc PF09335.11 EMC92870.1 - 0.055 14.0 0.1 0.055 14.0 0.1 4.0 2 2 1 4 4 4 0 SNARE associated Golgi protein TMF_TATA_bd PF12325.8 EMC92870.1 - 0.06 13.6 1.2 0.18 12.0 0.2 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YMF19 PF02326.15 EMC92870.1 - 0.065 14.0 0.4 0.065 14.0 0.4 2.8 2 0 0 2 2 2 0 Plant ATP synthase F0 AAA_13 PF13166.6 EMC92870.1 - 0.11 11.2 0.6 0.18 10.4 0.6 1.3 1 0 0 1 1 1 0 AAA domain DUF4064 PF13273.6 EMC92870.1 - 0.16 12.3 0.2 0.16 12.3 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) CDC45 PF02724.14 EMC92871.1 - 0.33 9.2 5.2 0.51 8.6 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EMC92871.1 - 0.93 7.6 14.0 1.3 7.1 14.0 1.1 1 0 0 1 1 1 0 Nop14-like family Aldo_ket_red PF00248.21 EMC92872.1 - 1.1e-50 172.5 0.0 3.2e-50 171.0 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.6 EMC92873.1 - 1.4e-21 76.5 0.0 2.7e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC92873.1 - 1.5e-18 66.6 0.0 3.5e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EMC92873.1 - 0.038 14.1 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMC92873.1 - 0.044 14.1 0.1 1.1 9.5 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase AlkA_N PF06029.11 EMC92875.1 - 0.0019 18.5 0.1 0.029 14.6 0.0 2.4 2 0 0 2 2 2 1 AlkA N-terminal domain LRR_8 PF13855.6 EMC92875.1 - 0.0092 15.7 5.0 0.0092 15.7 5.0 2.6 2 0 0 2 2 2 1 Leucine rich repeat F-box-like PF12937.7 EMC92875.1 - 0.056 13.3 0.3 0.15 11.9 0.3 1.8 1 1 0 1 1 1 0 F-box-like CUE PF02845.16 EMC92877.1 - 8.5e-12 44.5 0.0 1.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain RRM_1 PF00076.22 EMC92879.1 - 8.2e-24 83.2 0.0 3.8e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC92879.1 - 0.0004 20.2 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif ETF_QO PF05187.13 EMC92880.1 - 8.9e-48 160.7 0.4 1.4e-47 160.1 0.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EMC92880.1 - 1.4e-08 34.7 0.1 0.00042 20.0 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC92880.1 - 2.7e-06 27.5 0.0 2e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMC92880.1 - 1.3e-05 24.5 0.8 0.0075 15.4 0.6 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EMC92880.1 - 1.3e-05 24.5 0.0 4.3e-05 22.9 0.0 1.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC92880.1 - 0.00016 21.0 0.0 0.0072 15.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EMC92880.1 - 0.00033 20.2 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC92880.1 - 0.00043 19.1 0.3 0.00063 18.6 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 EMC92880.1 - 0.00052 19.0 0.0 0.2 10.5 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EMC92880.1 - 0.00061 19.1 0.1 0.0018 17.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EMC92880.1 - 0.00075 20.0 0.2 2.2 8.9 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC92880.1 - 0.0066 16.4 0.3 0.017 15.1 0.3 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMC92880.1 - 0.0076 15.5 0.2 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 EMC92880.1 - 0.025 15.1 1.0 0.09 13.4 1.0 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 EMC92880.1 - 0.052 12.6 0.2 0.078 12.0 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EMC92880.1 - 0.1 11.6 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EMC92880.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_23 PF13489.6 EMC92886.1 - 1.3e-23 83.7 0.0 1.8e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC92886.1 - 1.4e-08 35.3 0.0 3.9e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC92886.1 - 7.2e-06 26.6 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC92886.1 - 0.00026 21.7 0.0 0.00089 20.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC92886.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC92886.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 EMC92886.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme CbiG_C PF01890.16 EMC92886.1 - 0.16 12.5 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus DAO PF01266.24 EMC92887.1 - 5.8e-42 144.5 0.7 6.8e-42 144.3 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMC92887.1 - 4.1e-07 30.1 0.3 0.021 14.8 0.3 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMC92887.1 - 1.1e-06 28.1 0.0 0.03 13.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC92887.1 - 1.1e-05 25.6 0.0 2.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EMC92887.1 - 0.00039 19.6 0.0 0.0026 16.9 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EMC92887.1 - 0.004 16.0 0.0 0.74 8.6 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 EMC92887.1 - 0.0062 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EMC92887.1 - 0.089 13.4 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC92887.1 - 0.25 10.4 0.0 0.51 9.4 0.0 1.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TBP PF00352.21 EMC92888.1 - 1.4e-67 223.7 0.1 8.1e-33 112.2 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EMC92888.1 - 3.1e-05 24.0 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EMC92888.1 - 0.11 12.3 0.1 0.62 9.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) COesterase PF00135.28 EMC92889.1 - 1.5e-59 202.3 0.1 1.8e-59 202.0 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC92889.1 - 0.00013 21.8 0.4 0.00079 19.3 0.0 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC92889.1 - 0.00033 20.2 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tagatose_6_P_K PF08013.11 EMC92890.1 - 0.14 10.8 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Not1 PF04054.15 EMC92891.1 - 8.4e-106 354.0 0.0 2.5e-105 352.4 0.0 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EMC92891.1 - 1.6e-84 282.8 3.1 1.6e-84 282.8 3.1 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EMC92891.1 - 9e-48 161.9 1.8 2.2e-47 160.7 1.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 EMC92891.1 - 5.4e-36 123.9 0.3 1.5e-35 122.5 0.3 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 EMC92891.1 - 1.5e-34 118.8 0.0 4.2e-34 117.4 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Spc29 PF17082.5 EMC92892.1 - 0.025 14.4 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 ALS2CR8 PF15299.6 EMC92893.1 - 2.5 8.0 11.7 5.9 6.7 11.7 1.7 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 CFEM PF05730.11 EMC92894.1 - 7.5e-05 22.7 5.5 7.5e-05 22.7 5.5 3.6 3 0 0 3 3 3 1 CFEM domain MFS_1 PF07690.16 EMC92895.1 - 3.4e-32 111.7 10.7 1.4e-16 60.4 5.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC92895.1 - 3.8e-06 26.0 11.9 0.00014 20.8 2.4 3.1 1 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EMC92895.1 - 0.00018 20.5 8.6 0.00018 20.5 8.6 2.3 1 1 0 2 2 2 2 MFS_1 like family DUF3007 PF11460.8 EMC92895.1 - 0.069 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) OATP PF03137.20 EMC92895.1 - 0.069 11.4 4.3 0.14 10.4 0.0 3.0 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EMC92895.1 - 0.47 8.8 9.7 0.027 12.9 0.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DAHP_synth_1 PF00793.20 EMC92896.1 - 5.5e-99 330.5 0.0 6.9e-99 330.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Got1 PF04178.12 EMC92897.1 - 1.4e-14 54.4 13.8 1.7e-14 54.2 13.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.8 EMC92897.1 - 0.025 14.8 1.6 0.025 14.8 1.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Peptidase_C32 PF05411.12 EMC92897.1 - 0.087 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase CPP1-like PF11833.8 EMC92897.1 - 0.7 9.5 5.3 0.84 9.3 5.3 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF373 PF04123.13 EMC92897.1 - 2.2 7.6 6.8 2.3 7.6 4.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Lipase_3 PF01764.25 EMC92898.1 - 1.5e-05 24.9 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EMC92898.1 - 0.0053 16.0 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EMC92898.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EMC92898.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF908 PF06012.12 EMC92898.1 - 0.86 9.0 5.7 1.3 8.3 5.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) VPS9 PF02204.18 EMC92899.1 - 6.1e-26 90.6 0.0 1.1e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EMC92899.1 - 0.085 13.2 0.0 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) Oxidored-like PF09791.9 EMC92900.1 - 3.2e-25 87.5 2.8 5e-25 86.9 2.8 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal AMP-binding PF00501.28 EMC92901.1 - 3.8e-84 282.7 0.1 6e-84 282.1 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC92901.1 - 9.5e-15 55.3 2.3 1.6e-13 51.4 0.6 3.4 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain DUF4079 PF13301.6 EMC92902.1 - 0.033 14.3 1.3 0.11 12.7 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) PhoLip_ATPase_C PF16212.5 EMC92902.1 - 1 9.0 6.3 0.59 9.8 4.2 1.5 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal dCMP_cyt_deam_1 PF00383.23 EMC92903.1 - 8.6e-09 35.2 0.3 4.3e-06 26.5 0.0 2.7 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region GMC_oxred_N PF00732.19 EMC92904.1 - 3.4e-41 141.5 0.0 5.2e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC92904.1 - 2.9e-33 115.4 0.0 5.1e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMC92904.1 - 2.9e-06 26.6 7.2 0.00028 20.1 7.2 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EMC92904.1 - 5.7e-06 25.6 0.0 0.0026 16.9 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 EMC92904.1 - 9.7e-06 25.4 3.2 0.00021 21.0 1.3 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC92904.1 - 2.4e-05 23.7 1.2 3.3e-05 23.3 0.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC92904.1 - 0.0004 20.6 2.1 0.0011 19.1 2.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMC92904.1 - 0.00093 18.0 0.4 0.0013 17.5 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EMC92904.1 - 0.0015 17.8 2.3 0.26 10.5 1.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC92904.1 - 0.054 12.4 0.9 0.082 11.7 0.9 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 EMC92904.1 - 0.059 13.9 1.5 0.13 12.8 1.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC92904.1 - 0.062 12.5 0.2 0.12 11.6 0.2 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EMC92904.1 - 0.063 13.5 0.8 0.13 12.6 0.8 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 EMC92904.1 - 0.081 12.0 1.2 0.13 11.3 0.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 EMC92904.1 - 0.085 12.1 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EMC92904.1 - 0.33 10.3 2.7 0.57 9.5 1.7 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase TauD PF02668.16 EMC92905.1 - 9.2e-45 153.5 0.3 1.2e-44 153.2 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EMC92905.1 - 1.3e-06 29.0 0.4 6.7e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 EMC92905.1 - 0.00081 18.6 0.1 0.015 14.4 0.0 2.0 2 0 0 2 2 2 1 CsiD Big_4 PF07532.11 EMC92905.1 - 0.019 14.7 0.1 0.091 12.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) AAA PF00004.29 EMC92906.1 - 1.1e-39 135.9 0.0 2.1e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EMC92906.1 - 1.4e-19 69.8 0.2 2.9e-19 68.8 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EMC92906.1 - 3.3e-09 36.4 0.0 9.4e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EMC92906.1 - 9.6e-05 22.4 0.1 0.00044 20.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC92906.1 - 0.00012 22.5 2.5 0.016 15.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EMC92906.1 - 0.0003 20.6 0.0 0.00082 19.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMC92906.1 - 0.00041 20.5 0.3 0.0027 17.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMC92906.1 - 0.0032 17.7 2.2 0.085 13.1 0.0 3.0 2 1 0 3 3 3 1 AAA domain PhoH PF02562.16 EMC92906.1 - 0.0034 16.9 0.2 0.072 12.5 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EMC92906.1 - 0.0063 15.9 0.1 0.02 14.3 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EMC92906.1 - 0.011 15.0 1.0 0.02 14.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EMC92906.1 - 0.012 15.8 0.0 0.034 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain JIP_LZII PF16471.5 EMC92906.1 - 0.015 15.4 2.1 0.047 13.9 2.1 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II CLZ PF16526.5 EMC92906.1 - 0.023 15.0 3.9 0.033 14.5 1.7 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IstB_IS21 PF01695.17 EMC92906.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EMC92906.1 - 0.14 11.7 0.0 0.41 10.1 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EMC92906.1 - 0.36 10.6 0.0 0.36 10.6 0.0 3.0 2 2 1 3 3 2 0 AAA domain 4HBT PF03061.22 EMC92907.1 - 5.5e-09 36.2 0.0 1.9e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily ADH_zinc_N PF00107.26 EMC92908.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EMC92908.1 - 0.027 14.2 1.0 0.032 14.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) THF_DHG_CYH_C PF02882.19 EMC92908.1 - 0.044 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_3 PF01494.19 EMC92909.1 - 4.1e-16 59.2 5.3 3.1e-15 56.3 5.3 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMC92909.1 - 2.4e-05 24.5 1.1 8.2e-05 22.8 1.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC92909.1 - 5.1e-05 23.0 2.5 0.0053 16.4 1.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC92909.1 - 0.00054 19.3 0.8 0.054 12.7 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC92909.1 - 0.0016 17.4 3.8 0.22 10.3 0.0 2.6 2 1 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 EMC92909.1 - 0.0093 16.0 3.7 0.12 12.3 0.9 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EMC92909.1 - 0.017 14.4 0.3 0.22 10.8 0.0 2.7 3 1 1 4 4 4 0 Flavin containing amine oxidoreductase SE PF08491.10 EMC92909.1 - 0.041 12.9 0.0 0.073 12.1 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase GIDA PF01134.22 EMC92909.1 - 0.062 12.4 0.9 0.11 11.5 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EMC92909.1 - 0.091 11.5 0.2 0.15 10.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EMC92909.1 - 0.28 11.8 1.8 0.63 10.6 1.8 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC92909.1 - 0.79 8.7 5.6 0.74 8.8 2.8 2.1 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_11 PF00457.17 EMC92910.1 - 1.4e-53 181.2 12.1 1.5e-53 181.1 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 adh_short_C2 PF13561.6 EMC92912.1 - 1.3e-49 168.9 0.0 1.5e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC92912.1 - 2.9e-47 160.7 0.0 3.7e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC92912.1 - 1.6e-13 50.9 0.2 2.3e-13 50.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC92912.1 - 6.8e-06 25.7 0.1 1.2e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC92912.1 - 4.7e-05 22.9 0.2 8.4e-05 22.1 0.1 1.6 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMC92912.1 - 0.0036 17.2 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMC92912.1 - 0.0044 17.3 0.1 0.0069 16.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EMC92912.1 - 0.006 15.7 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ABC_tran PF00005.27 EMC92913.1 - 2.8e-33 115.3 0.0 6.5e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EMC92913.1 - 1.2e-25 90.7 4.4 2.5e-25 89.7 4.4 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EMC92913.1 - 1.6e-05 24.5 0.0 0.00015 21.3 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EMC92913.1 - 0.005 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 EMC92913.1 - 0.0053 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EMC92913.1 - 0.0068 16.7 0.5 0.075 13.3 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EMC92913.1 - 0.021 14.6 0.5 0.17 11.7 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EMC92913.1 - 0.026 14.2 0.0 0.058 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMC92913.1 - 0.027 14.9 0.5 0.12 12.7 0.5 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 EMC92913.1 - 0.062 12.2 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_21 PF13304.6 EMC92913.1 - 0.076 12.8 0.2 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EMC92913.1 - 0.087 12.4 0.1 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EMC92913.1 - 0.18 11.9 0.0 0.42 10.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase UPF0715 PF17094.5 EMC92913.1 - 0.9 10.1 6.7 0.38 11.3 0.8 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0715) Glyco_tranf_2_3 PF13641.6 EMC92914.1 - 2.3e-22 80.0 0.1 3.5e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMC92914.1 - 1.5e-12 47.6 0.0 3.3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EMC92914.1 - 3.4e-09 36.4 0.0 2.4e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_64 PF09258.10 EMC92914.1 - 0.0031 16.8 0.2 0.0052 16.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_trans_2_3 PF13632.6 EMC92914.1 - 0.01 15.7 4.7 0.019 14.9 4.7 1.5 1 1 0 1 1 1 0 Glycosyl transferase family group 2 DUF1324 PF07038.11 EMC92914.1 - 0.14 12.4 0.9 0.34 11.2 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) GalKase_gal_bdg PF10509.9 EMC92915.1 - 3.1e-21 74.7 0.0 5.9e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EMC92915.1 - 1.9e-14 53.6 1.8 4.5e-14 52.4 1.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMC92915.1 - 2.7e-14 53.3 0.0 8.2e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal MttA_Hcf106 PF02416.16 EMC92915.1 - 0.005 16.1 0.0 0.021 14.1 0.0 2.1 1 0 0 1 1 1 1 mttA/Hcf106 family Cytomega_TRL10 PF06084.11 EMC92917.1 - 0.19 11.8 2.9 0.23 11.5 2.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Pkinase PF00069.25 EMC92918.1 - 3.4e-17 62.7 0.0 4.5e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92918.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase FA_hydroxylase PF04116.13 EMC92919.1 - 1.7e-26 93.2 17.2 1.7e-26 93.2 17.2 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily NCA2 PF08637.10 EMC92921.1 - 2.3e-110 368.3 0.1 4.3e-110 367.5 0.0 1.5 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Ras PF00071.22 EMC92922.1 - 7.4e-66 220.7 0.1 8.9e-66 220.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC92922.1 - 7.1e-34 116.6 0.5 1.3e-33 115.7 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC92922.1 - 1.3e-13 50.8 0.1 1.7e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMC92922.1 - 4e-06 26.5 0.1 7.4e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMC92922.1 - 7.9e-05 22.1 0.1 9.3e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EMC92922.1 - 0.0022 17.9 0.7 1.7 8.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMC92922.1 - 0.0033 17.5 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMC92922.1 - 0.051 13.1 0.0 0.26 10.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 EMC92922.1 - 0.08 13.4 0.0 7.4 7.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMC92922.1 - 0.089 13.1 0.1 1.1 9.6 0.0 2.2 1 1 0 2 2 2 0 AAA domain TMA7 PF09072.10 EMC92923.1 - 3.8e-16 59.7 18.0 4.1e-16 59.5 18.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF4407 PF14362.6 EMC92923.1 - 0.85 8.9 3.7 0.83 8.9 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UCH PF00443.29 EMC92924.1 - 3.4e-34 118.5 0.0 4.3e-30 105.1 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC92924.1 - 2.9e-08 33.7 0.2 2.7e-07 30.5 0.2 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase InaF-motif PF15018.6 EMC92924.1 - 1 9.3 4.4 0.87 9.5 0.5 2.2 2 0 0 2 2 2 0 TRP-interacting helix NAD_binding_10 PF13460.6 EMC92925.1 - 1.7e-09 37.8 0.0 7.6e-08 32.5 0.0 2.3 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EMC92925.1 - 6.8e-07 29.0 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EMC92925.1 - 0.02 15.0 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 EMC92925.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EMC92925.1 - 0.096 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cyclin_N PF00134.23 EMC92926.1 - 1.1e-13 51.1 0.9 4.8e-13 49.0 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EMC92926.1 - 0.43 10.7 5.2 11 6.2 0.9 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Ribosomal_L9_N PF01281.19 EMC92927.1 - 1.2e-12 47.2 0.0 2.4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EMC92927.1 - 0.0095 16.4 0.0 0.029 14.8 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L9, C-terminal domain DUF3136 PF11334.8 EMC92928.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Pkinase PF00069.25 EMC92932.1 - 6.4e-52 176.5 0.0 8.1e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92932.1 - 1.3e-30 106.6 0.0 1.5e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC92932.1 - 0.00017 21.0 0.0 0.00093 18.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EMC92932.1 - 0.0088 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMC92932.1 - 0.026 13.5 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EMC92932.1 - 0.055 12.8 0.1 0.082 12.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EMC92932.1 - 0.095 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 EMC92933.1 - 7.5e-50 169.7 0.0 1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92933.1 - 3.9e-23 82.1 0.0 8.6e-23 80.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EMC92933.1 - 0.023 14.6 0.5 2.5 7.9 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EMC92933.1 - 0.035 13.1 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pribosyltran PF00156.27 EMC92934.1 - 9.5e-09 35.0 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain LRR_4 PF12799.7 EMC92936.1 - 3e-28 97.4 29.9 0.00048 20.5 0.1 9.7 6 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMC92936.1 - 6.2e-28 96.3 36.0 1.3e-07 31.2 1.3 9.1 4 3 3 9 9 9 7 Leucine rich repeat LRR_6 PF13516.6 EMC92936.1 - 1.1e-08 34.4 25.8 5.6 7.3 0.0 12.0 13 0 0 13 13 13 4 Leucine Rich repeat LRR_1 PF00560.33 EMC92936.1 - 1.3e-08 34.2 25.9 4.4 8.2 0.6 13.2 12 1 1 13 13 13 2 Leucine Rich Repeat LRR_9 PF14580.6 EMC92936.1 - 0.00057 19.4 14.5 0.098 12.2 0.4 4.8 2 2 3 5 5 5 4 Leucine-rich repeat SlyX PF04102.12 EMC92937.1 - 0.064 13.9 5.2 0.073 13.7 0.3 3.2 2 0 0 2 2 2 0 SlyX DUF3491 PF11996.8 EMC92937.1 - 0.12 10.2 0.1 0.16 9.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) DUF2353 PF09789.9 EMC92937.1 - 0.56 9.5 9.4 2.1 7.6 1.0 3.0 3 0 0 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) GRIP PF01465.20 EMC92941.1 - 4.9e-14 52.0 0.1 1.4e-13 50.5 0.1 1.9 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 EMC92941.1 - 0.0025 16.8 30.0 0.0025 16.8 30.0 10.2 3 2 5 9 9 9 6 Spc7 kinetochore protein GAS PF13851.6 EMC92941.1 - 0.0063 15.9 8.6 0.0063 15.9 8.6 11.4 3 3 8 11 11 11 8 Growth-arrest specific micro-tubule binding DUF383 PF04063.14 EMC92942.1 - 9e-66 221.2 0.0 8.6e-65 218.0 0.0 2.3 3 1 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EMC92942.1 - 4.9e-23 80.7 0.7 9.5e-23 79.8 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) PAP_assoc PF03828.19 EMC92943.1 - 7.6e-20 70.9 0.0 1.9e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EMC92943.1 - 5.4e-06 26.6 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EMC92943.1 - 0.044 13.9 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 EMC92943.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm PRCC PF10253.9 EMC92943.1 - 2.4 8.9 6.4 1.2 9.9 0.8 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Hva1_TUDOR PF11160.8 EMC92945.1 - 3.9e-16 59.0 3.5 3.9e-16 59.0 3.5 2.6 2 1 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain zf-HYPF PF07503.12 EMC92946.1 - 0.15 11.9 1.0 0.28 11.0 1.0 1.5 1 0 0 1 1 1 0 HypF finger Pkinase PF00069.25 EMC92947.1 - 3.1e-69 233.3 0.0 4.1e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC92947.1 - 5.8e-32 111.0 0.0 8e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EMC92947.1 - 1.8e-13 50.9 0.4 8e-13 48.9 0.4 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EMC92947.1 - 7.2e-09 35.9 0.0 3.6e-08 33.6 0.0 2.2 3 0 0 3 3 3 1 C2 domain Kinase-like PF14531.6 EMC92947.1 - 9.1e-09 35.0 0.1 6.8e-08 32.2 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EMC92947.1 - 0.00095 18.2 0.1 0.0019 17.2 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EMC92947.1 - 0.0023 17.6 0.2 0.92 9.1 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EMC92947.1 - 0.0033 17.4 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EMC92947.1 - 0.04 13.3 0.1 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EMC92947.1 - 0.15 11.6 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MaoC_dehydratas PF01575.19 EMC92948.1 - 9.9e-25 86.5 0.0 2.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EMC92948.1 - 3.3e-06 27.3 0.0 0.0004 20.5 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase ECH_1 PF00378.20 EMC92950.1 - 3.7e-75 252.5 0.0 4.6e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMC92950.1 - 7.6e-36 124.3 0.1 3.2e-33 115.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 EMC92951.1 - 9.7e-76 253.3 4.6 1.1e-75 253.1 4.6 1.0 1 0 0 1 1 1 1 Rer1 family Oxidored_q4 PF00507.19 EMC92951.1 - 0.047 13.8 1.3 0.047 13.8 1.3 1.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF3419 PF11899.8 EMC92952.1 - 7e-156 519.2 0.0 9e-156 518.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EMC92952.1 - 1.2e-10 41.4 0.0 8.8e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC92952.1 - 1.4e-09 38.6 0.0 4.1e-08 33.9 0.0 3.3 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC92952.1 - 6.3e-08 33.2 0.0 3.3e-06 27.7 0.0 3.6 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC92952.1 - 5.8e-06 26.9 0.0 0.0013 19.4 0.0 3.9 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC92952.1 - 2e-05 24.4 0.0 9.2e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC92952.1 - 0.007 15.7 0.0 0.27 10.5 0.0 2.7 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EMC92952.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EMC92952.1 - 0.063 12.7 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase Orn_Arg_deC_N PF02784.16 EMC92952.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain NADH_u_ox_C PF12853.7 EMC92953.1 - 1.9e-26 91.9 0.0 3.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 EMC92953.1 - 4.8e-24 84.9 0.0 9.3e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Cyclin PF08613.11 EMC92954.1 - 1.8e-14 54.4 0.1 4.5e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EMC92954.1 - 3.4e-06 26.8 0.1 7e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain UFD1 PF03152.14 EMC92956.1 - 1.4e-26 93.0 0.0 3.5e-13 49.4 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EMC92956.1 - 3.1e-06 27.3 0.2 3.1e-06 27.3 0.2 2.3 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DNA_RNApol_7kD PF03604.13 EMC92956.1 - 0.0067 16.1 0.3 3 7.6 0.1 3.1 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit Elf1 PF05129.13 EMC92956.1 - 0.13 12.3 1.0 9.9 6.3 0.0 3.0 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like XAF1_C PF18608.1 EMC92956.1 - 0.29 10.7 5.6 0.13 11.9 0.4 2.6 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain zinc_ribbon_4 PF13717.6 EMC92956.1 - 2.2 8.3 5.5 1.2 9.1 0.0 3.2 4 0 0 4 4 4 0 zinc-ribbon domain zf_C2HC_14 PF18574.1 EMC92956.1 - 6.2 6.7 6.2 0.53 10.1 0.8 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain CRC_subunit PF08624.10 EMC92957.1 - 1.4e-51 174.5 0.0 2e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit BTB PF00651.31 EMC92958.1 - 1.2e-07 32.0 0.0 5.1e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 EMC92958.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain UQ_con PF00179.26 EMC92959.1 - 2.1e-40 137.6 0.0 2.4e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMC92959.1 - 0.00035 20.3 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMC92959.1 - 0.0005 20.3 0.0 0.00067 19.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EMC92959.1 - 0.046 13.6 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain RabGAP-TBC PF00566.18 EMC92960.1 - 4.2e-34 118.1 0.0 1.6e-31 109.7 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF2439 PF10382.9 EMC92960.1 - 0.084 13.2 0.4 0.16 12.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) Ferric_reduct PF01794.19 EMC92964.1 - 4.1e-20 72.2 9.3 4.1e-20 72.2 9.3 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMC92964.1 - 1.3e-09 38.4 0.0 0.00014 22.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMC92964.1 - 6.3e-09 35.9 0.0 2.3e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EMC92964.1 - 0.00041 21.0 0.0 0.00074 20.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ribosomal_L30_N PF08079.12 EMC92965.1 - 1.2e-27 95.9 19.7 1.2e-27 95.9 19.7 1.8 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EMC92965.1 - 4e-17 61.8 2.7 4e-17 61.8 2.7 2.1 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e CSRNP_N PF16019.5 EMC92965.1 - 0.011 15.7 3.6 0.016 15.2 3.6 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FRG1 PF06229.12 EMC92965.1 - 0.22 11.2 6.8 0.36 10.5 6.8 1.3 1 0 0 1 1 1 0 FRG1-like domain adh_short_C2 PF13561.6 EMC92966.1 - 3.4e-32 111.9 0.0 1.1e-31 110.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC92966.1 - 1.7e-25 89.6 0.0 2.3e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC92966.1 - 0.13 12.1 0.1 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 KR domain RINGv PF12906.7 EMC92967.1 - 1.6e-05 25.0 6.4 3e-05 24.1 6.4 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EMC92967.1 - 3e-05 24.1 3.2 5.4e-05 23.3 3.2 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EMC92967.1 - 0.13 12.6 9.3 0.26 11.6 9.3 1.5 1 1 0 1 1 1 0 Ring finger domain SNF2_N PF00176.23 EMC92968.1 - 1.2e-66 224.8 0.1 2.3e-66 223.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC92968.1 - 1.9e-19 70.0 0.0 4.4e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC92968.1 - 1.7e-06 28.1 0.0 5.9e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 EMC92968.1 - 0.037 14.2 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain Snapin_Pallidin PF14712.6 EMC92968.1 - 0.054 13.9 1.9 0.14 12.6 1.9 1.7 1 0 0 1 1 1 0 Snapin/Pallidin ERCC3_RAD25_C PF16203.5 EMC92968.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CENP-F_leu_zip PF10473.9 EMC92968.1 - 1.3 9.0 9.0 1.1 9.2 5.8 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_11 PF13086.6 EMC92968.1 - 4.6 6.9 0.0 4.6 6.9 0.0 3.6 5 0 0 5 5 5 0 AAA domain bZIP_1 PF00170.21 EMC92969.1 - 1.8e-07 31.1 7.7 3.4e-07 30.3 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMC92969.1 - 4.6e-06 26.6 10.3 9.6e-06 25.6 10.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Eapp_C PF10238.9 EMC92969.1 - 0.076 13.1 0.5 0.18 11.8 0.5 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein bZIP_Maf PF03131.17 EMC92969.1 - 0.085 13.4 8.2 0.27 11.8 8.2 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF61 PF01886.16 EMC92970.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF61 Fumble PF03630.14 EMC92972.1 - 3.2e-143 476.9 0.2 4.1e-143 476.5 0.2 1.1 1 0 0 1 1 1 1 Fumble Rtf2 PF04641.12 EMC92973.1 - 4e-57 193.6 0.5 4.9e-57 193.3 0.5 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EMC92973.1 - 9.1e-06 25.4 0.0 0.00041 20.1 0.0 2.5 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EMC92973.1 - 0.03 14.3 0.2 0.071 13.2 0.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EMC92973.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain GMC_oxred_N PF00732.19 EMC92974.1 - 5e-51 173.8 0.0 6.5e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC92974.1 - 7.6e-36 123.8 0.0 1.2e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMC92974.1 - 1.5e-05 24.3 0.0 0.047 12.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EMC92974.1 - 6.5e-05 23.1 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMC92974.1 - 0.00014 21.0 0.0 0.00026 20.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EMC92974.1 - 0.00016 21.3 0.1 0.018 14.6 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC92974.1 - 0.012 14.9 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC92974.1 - 0.018 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 EMC92974.1 - 0.041 14.4 0.0 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMC92974.1 - 0.076 12.3 0.0 0.76 9.1 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Aldedh PF00171.22 EMC92975.1 - 3.2e-153 510.6 0.0 3.8e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NCD1 PF04904.13 EMC92975.1 - 0.14 12.2 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Myb_DNA-binding PF00249.31 EMC92976.1 - 0.0051 17.0 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aldo_ket_red PF00248.21 EMC92977.1 - 7.8e-59 199.3 0.0 1.1e-58 198.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C3HC4_3 PF13920.6 EMC92978.1 - 0.58 10.1 6.4 0.49 10.3 3.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0016 PF01169.19 EMC92979.1 - 5.4e-42 142.0 24.7 5.1e-21 74.8 7.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF3357 PF11837.8 EMC92979.1 - 0.15 12.6 6.7 0.19 12.2 0.2 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Glyco_hydro_92 PF07971.12 EMC92980.1 - 4.5e-134 447.9 2.9 5.5e-134 447.6 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMC92980.1 - 6.4e-54 183.4 4.3 9e-54 182.9 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain I-EGF_1 PF18372.1 EMC92980.1 - 0.23 11.6 0.5 0.49 10.5 0.5 1.5 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 F-box-like PF12937.7 EMC92982.1 - 0.00046 20.0 0.2 0.0015 18.4 0.2 2.0 1 0 0 1 1 1 1 F-box-like NOB1_Zn_bind PF08772.11 EMC92982.1 - 0.14 12.4 1.8 0.32 11.2 1.8 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Seipin PF06775.14 EMC92983.1 - 4.6e-58 196.6 0.8 6.3e-58 196.1 0.8 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) UPF0242 PF06785.11 EMC92984.1 - 2 8.5 5.4 11 6.1 5.4 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3584 PF12128.8 EMC92985.1 - 0.0058 14.2 0.7 0.0074 13.9 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Cep57_CLD_2 PF14197.6 EMC92985.1 - 0.019 15.1 0.3 0.052 13.6 0.3 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 EMC92985.1 - 0.27 11.2 4.5 0.47 10.5 2.1 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Na_Ca_ex PF01699.24 EMC92986.1 - 2.3e-21 76.3 36.6 1.1e-14 54.6 14.1 3.6 4 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 EMC92986.1 - 1.6e-14 54.4 10.7 1.6e-14 54.4 10.7 5.0 5 0 0 5 5 5 1 Inner membrane component domain Nop14 PF04147.12 EMC92986.1 - 1.1 7.4 9.2 1.5 7.0 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 EMC92986.1 - 1.2 8.7 5.7 2.5 7.7 5.7 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TFIIF_alpha PF05793.12 EMC92986.1 - 9.7 4.6 14.5 18 3.8 14.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA PF00004.29 EMC92987.1 - 7.6e-44 149.3 0.0 1.2e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMC92987.1 - 9.1e-15 54.2 0.4 3e-14 52.6 0.1 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EMC92987.1 - 9.8e-08 32.1 0.0 2.5e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMC92987.1 - 1.3e-07 31.9 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EMC92987.1 - 1.3e-06 28.9 0.1 8.3e-05 23.0 0.1 2.9 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EMC92987.1 - 1.2e-05 25.2 1.1 3.3e-05 23.8 1.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EMC92987.1 - 2.1e-05 24.8 0.2 0.0056 17.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMC92987.1 - 5.5e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EMC92987.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EMC92987.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMC92987.1 - 0.0024 18.4 0.0 0.018 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EMC92987.1 - 0.0026 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EMC92987.1 - 0.0036 17.1 0.0 0.0095 15.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EMC92987.1 - 0.0057 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 EMC92987.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EMC92987.1 - 0.0098 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EMC92987.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EMC92987.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EMC92987.1 - 0.021 14.5 0.0 0.09 12.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Prot_ATP_OB_N PF17758.1 EMC92987.1 - 0.022 14.4 0.0 0.078 12.6 0.0 2.0 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_7 PF12775.7 EMC92987.1 - 0.026 14.0 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EMC92987.1 - 0.03 13.9 0.1 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EMC92987.1 - 0.033 13.6 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein HR1 PF02185.16 EMC92987.1 - 0.034 14.2 0.9 0.082 13.0 0.9 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_14 PF13173.6 EMC92987.1 - 0.035 14.1 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMC92987.1 - 0.036 14.5 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EMC92987.1 - 0.04 13.6 0.0 0.096 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EMC92987.1 - 0.06 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EMC92987.1 - 0.093 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PrsW-protease PF13367.6 EMC92988.1 - 1.5e-08 34.3 8.1 1.5e-08 34.3 8.1 2.1 1 1 1 2 2 2 1 PrsW family intramembrane metalloprotease CMD PF02627.20 EMC92988.1 - 0.02 14.9 2.1 0.076 13.1 1.9 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family DJ-1_PfpI PF01965.24 EMC92990.1 - 8.6e-09 35.4 0.0 1.6e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family XH PF03469.14 EMC92991.1 - 0.0015 18.4 2.4 0.3 11.0 0.0 3.7 3 1 1 4 4 4 1 XH domain Elf4 PF07011.11 EMC92991.1 - 0.0061 16.4 0.4 0.025 14.5 0.2 2.1 2 0 0 2 2 2 1 Early Flowering 4 domain CarD_CdnL_TRCF PF02559.16 EMC92991.1 - 0.02 15.6 3.2 0.095 13.4 0.0 3.4 2 1 1 4 4 4 0 CarD-like/TRCF domain RB_A PF01858.17 EMC92991.1 - 0.16 11.8 2.3 5.3 6.8 0.1 3.1 3 0 0 3 3 3 0 Retinoblastoma-associated protein A domain DUF883 PF05957.13 EMC92991.1 - 0.71 10.5 10.9 1.2e+02 3.4 0.0 5.4 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EMC92991.1 - 4.9 7.7 14.1 21 5.7 0.0 5.1 4 2 0 4 4 4 0 YtxH-like protein SWIRM-assoc_2 PF16496.5 EMC92992.1 - 0.3 9.9 3.2 0.46 9.3 3.2 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal zf-RING_2 PF13639.6 EMC92993.1 - 3.6e-11 43.2 4.6 5.7e-11 42.6 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EMC92993.1 - 1.8e-09 37.1 1.5 3.3e-09 36.3 1.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EMC92993.1 - 3.6e-07 29.9 2.6 5.8e-07 29.3 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC92993.1 - 7.8e-07 28.8 4.2 1.2e-06 28.2 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMC92993.1 - 1.1e-05 25.6 5.9 3.7e-05 23.9 5.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EMC92993.1 - 1.7e-05 24.6 3.9 2.9e-05 23.8 3.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EMC92993.1 - 0.00039 20.3 1.6 0.0006 19.7 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMC92993.1 - 0.0021 18.0 3.8 0.0041 17.1 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMC92993.1 - 0.0035 17.4 0.5 0.0089 16.1 0.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EMC92993.1 - 0.018 14.9 1.3 0.031 14.1 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EMC92993.1 - 0.078 12.8 3.4 0.13 12.0 3.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Peptidase_C6 PF00851.18 EMC92993.1 - 0.11 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Helper component proteinase PHD PF00628.29 EMC92993.1 - 0.62 10.0 2.3 1.1 9.2 2.3 1.4 1 0 0 1 1 1 0 PHD-finger adh_short PF00106.25 EMC92994.1 - 1.2e-20 73.8 0.5 5.3e-20 71.7 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC92994.1 - 5e-16 59.0 0.2 1.6e-15 57.3 0.1 1.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC92994.1 - 7.8e-09 35.7 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC92994.1 - 0.0006 19.3 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMC92994.1 - 0.00084 18.6 0.4 0.007 15.6 0.0 1.9 1 1 0 2 2 2 1 Male sterility protein Pyr_redox_3 PF13738.6 EMC92994.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BTB PF00651.31 EMC92995.1 - 0.034 14.4 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain PRMT5 PF05185.16 EMC92996.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase MFS_1 PF07690.16 EMC92997.1 - 1.4e-24 86.8 23.7 1.4e-24 86.8 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC92997.1 - 1.1e-11 44.2 6.8 1.1e-11 44.2 6.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Ras PF00071.22 EMC92998.1 - 2.9e-40 137.5 0.0 1.4e-37 128.8 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EMC92998.1 - 1.7e-30 105.7 0.0 2.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC92998.1 - 3.2e-11 43.0 0.0 5.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMC92998.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EMC92998.1 - 0.0027 18.1 0.0 0.0038 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 EMC92998.1 - 0.0096 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 EMC92998.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EMC92998.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Septin NACHT PF05729.12 EMC92998.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EMC92998.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EMC92998.1 - 0.14 12.1 0.1 0.37 10.7 0.1 1.8 1 1 1 2 2 2 0 RsgA GTPase TniB PF05621.11 EMC92998.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 EMC92998.1 - 0.23 10.9 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Rubredoxin_2 PF18073.1 EMC92999.1 - 4.2 7.2 5.5 9.9 6.0 0.4 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain AXE1 PF05448.12 EMC93000.1 - 0.0086 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) bZIP_1 PF00170.21 EMC93002.1 - 5.8e-09 35.9 12.3 2.2e-08 34.1 12.3 1.9 1 1 0 1 1 1 1 bZIP transcription factor CNTF PF01110.17 EMC93002.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ciliary neurotrophic factor DUF501 PF04417.12 EMC93002.1 - 0.12 12.2 0.2 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) bZIP_2 PF07716.15 EMC93002.1 - 0.9 9.7 15.5 76 3.5 15.5 2.4 1 1 0 1 1 1 0 Basic region leucine zipper DUF4653 PF15546.6 EMC93004.1 - 0.079 12.6 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Fungal_trans PF04082.18 EMC93006.1 - 8.3e-15 54.5 0.0 1.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93006.1 - 5.8e-08 32.7 11.2 9.1e-08 32.1 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFA PF04828.14 EMC93007.1 - 6.2e-20 71.3 7.8 8e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NTP_transf_2 PF01909.23 EMC93008.1 - 2.6e-09 37.2 0.0 6.5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EMC93008.1 - 6.5e-09 35.9 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase UBA_2 PF08587.11 EMC93008.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Metallophos PF00149.28 EMC93010.1 - 4.1e-10 40.5 4.4 9.4e-10 39.3 4.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EMC93010.1 - 0.037 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain eIF-3c_N PF05470.12 EMC93011.1 - 6.1e-165 549.9 24.7 6.1e-165 549.9 24.7 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EMC93011.1 - 2e-14 53.9 1.3 9.5e-14 51.8 0.1 2.9 3 0 0 3 3 3 1 PCI domain Rhamno_transf PF11316.8 EMC93011.1 - 0.031 13.7 0.0 0.072 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative rhamnosyl transferase CDC45 PF02724.14 EMC93011.1 - 0.16 10.2 13.5 0.26 9.5 13.5 1.3 1 0 0 1 1 1 0 CDC45-like protein TraT PF05818.12 EMC93011.1 - 3.3 7.4 5.3 7 6.3 5.3 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein IBR PF01485.21 EMC93012.1 - 2.2e-11 43.8 20.2 3.6e-07 30.3 5.8 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain RRM_1 PF00076.22 EMC93012.1 - 0.048 13.5 0.0 15 5.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1543 PF07566.12 EMC93012.1 - 0.081 12.7 0.1 0.25 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) Med11 PF10280.9 EMC93013.1 - 0.086 13.3 2.6 0.14 12.7 2.2 1.6 1 1 0 1 1 1 0 Mediator complex protein Na_Ca_ex PF01699.24 EMC93014.1 - 3.3e-38 131.0 44.7 4.8e-19 68.8 14.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4746 PF15928.5 EMC93014.1 - 1.2 8.4 6.4 5.4 6.3 6.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) WW_FCH_linker PF16623.5 EMC93014.1 - 5.4 7.8 6.6 0.8 10.5 1.5 2.3 2 0 0 2 2 2 0 Unstructured linker region between on GAS7 protein DUF3087 PF11286.8 EMC93014.1 - 6.6 6.2 6.3 0.44 10.0 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) SpoIIIAH PF12685.7 EMC93014.1 - 6.6 6.5 12.7 35 4.1 12.7 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF4407 PF14362.6 EMC93014.1 - 7.1 5.9 6.8 21 4.4 6.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Actin PF00022.19 EMC93015.1 - 4.2e-25 88.2 0.0 3.1e-20 72.2 0.0 3.0 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.13 EMC93015.1 - 0.014 14.2 0.0 4.4 6.0 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Amidohydro_1 PF01979.20 EMC93016.1 - 4.5e-77 259.7 0.0 5.1e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMC93016.1 - 3.6e-11 43.2 1.0 5.2e-11 42.7 0.2 1.8 2 1 0 2 2 2 1 Amidohydrolase family Toxin_29 PF08116.11 EMC93016.1 - 0.081 12.9 0.3 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 PhTx neurotoxin family A_deaminase PF00962.22 EMC93016.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase Mob_synth_C PF06463.13 EMC93016.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C DUF1449 PF07290.11 EMC93017.1 - 0.046 13.3 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) GAF_2 PF13185.6 EMC93017.1 - 0.13 12.6 2.0 2.2 8.6 0.0 2.8 2 1 1 3 3 3 0 GAF domain Nop14 PF04147.12 EMC93017.1 - 6.2 4.9 6.9 8.3 4.5 6.9 1.0 1 0 0 1 1 1 0 Nop14-like family ATP_sub_h PF10775.9 EMC93018.1 - 4.7e-27 93.8 2.0 7e-27 93.2 2.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h TFIIB PF00382.19 EMC93019.1 - 1.5e-35 121.1 0.0 9.9e-19 67.2 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EMC93019.1 - 8e-12 44.5 0.2 1.3e-11 43.8 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_5 PF01022.20 EMC93019.1 - 0.0012 18.7 0.0 0.17 11.7 0.0 3.0 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family zf-ribbon_3 PF13248.6 EMC93019.1 - 0.26 10.7 0.1 0.26 10.7 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain His_Phos_2 PF00328.22 EMC93021.1 - 2.3e-106 356.4 1.6 3.7e-106 355.7 1.6 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EMC93021.1 - 8.8e-37 125.1 0.0 1.9e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EMC93021.1 - 3.3e-05 23.6 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ProQ PF04352.13 EMC93021.1 - 0.11 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 ProQ/FINO family Acyl-CoA_dh_1 PF00441.24 EMC93022.1 - 3.1e-34 118.4 0.6 5.2e-34 117.6 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EMC93022.1 - 4.9e-18 65.0 0.1 1.9e-17 63.1 0.1 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EMC93022.1 - 1.7e-17 63.4 0.3 3.4e-17 62.4 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMC93022.1 - 3.3e-08 34.2 0.5 1.3e-07 32.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMC93022.1 - 1.6e-06 28.4 0.0 3.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF5106 PF17127.4 EMC93022.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Metallophos PF00149.28 EMC93025.1 - 6.3e-13 49.7 1.7 1.3e-12 48.7 1.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMC93025.1 - 4.4e-06 27.0 0.0 1.1e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Anoctamin PF04547.12 EMC93026.1 - 9.3e-113 377.4 1.9 1.2e-112 377.1 1.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Noc2 PF03715.13 EMC93026.1 - 0.043 13.1 0.3 0.071 12.4 0.3 1.2 1 0 0 1 1 1 0 Noc2p family adh_short PF00106.25 EMC93027.1 - 8.6e-25 87.3 0.2 1e-24 87.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93027.1 - 1.7e-22 80.1 0.1 2.2e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMC93027.1 - 0.0018 17.8 0.2 0.5 9.8 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 EMC93027.1 - 0.0024 17.8 0.2 0.0056 16.6 0.2 1.6 1 1 1 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EMC93027.1 - 0.0033 16.9 0.8 0.63 9.4 0.1 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase His_biosynth PF00977.21 EMC93027.1 - 0.024 14.1 0.0 0.53 9.7 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein DCX PF03607.17 EMC93027.1 - 0.15 12.1 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 Doublecortin Wzz PF02706.15 EMC93027.1 - 0.16 12.3 0.4 0.28 11.5 0.4 1.3 1 0 0 1 1 1 0 Chain length determinant protein Cyclase PF04199.13 EMC93029.1 - 3.4e-13 50.0 0.0 4.7e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DSHCT PF08148.12 EMC93030.1 - 2.7e-50 170.3 0.2 7.8e-50 168.7 0.2 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EMC93030.1 - 4.6e-40 136.5 0.0 9.3e-40 135.6 0.0 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EMC93030.1 - 1.5e-26 94.0 0.0 2.5e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EMC93030.1 - 6.5e-18 65.1 0.0 1.4e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC93030.1 - 1.7e-06 28.3 0.0 5.4e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC93030.1 - 3.7e-05 23.8 0.0 9.3e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FDF PF09532.10 EMC93031.1 - 2.7 8.9 8.5 1.5 9.8 2.7 3.4 2 0 0 2 2 2 0 FDF domain PRKCSH-like PF12999.7 EMC93032.1 - 8.4e-43 146.2 6.2 2.4e-23 82.8 0.3 3.1 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EMC93032.1 - 1.1e-33 116.1 0.4 2.8e-33 114.8 0.1 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EMC93032.1 - 3.2e-10 40.9 0.1 1.4e-09 38.8 0.1 2.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Phage_GP20 PF06810.11 EMC93032.1 - 0.68 9.7 6.8 3.2 7.5 0.0 3.1 2 1 0 3 3 3 0 Phage minor structural protein GP20 FAM184 PF15665.5 EMC93032.1 - 0.81 9.4 8.6 0.94 9.2 5.2 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B TPR_MLP1_2 PF07926.12 EMC93032.1 - 1.4 9.0 10.2 8.7 6.4 0.3 3.4 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EMC93032.1 - 1.8 8.8 12.9 7.8 6.7 1.7 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 EMC93032.1 - 1.8 8.2 3.8 2.5 7.8 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Sec2p PF06428.11 EMC93032.1 - 1.9 8.5 4.6 14 5.7 0.4 3.0 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.20 EMC93032.1 - 9.3 6.3 8.9 6.6 6.7 1.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit Acetyltransf_3 PF13302.7 EMC93033.1 - 0.031 15.0 0.0 0.89 10.2 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3086 PF11285.8 EMC93033.1 - 1.6 7.7 7.8 3.1 6.8 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Peptidase_S10 PF00450.22 EMC93035.1 - 2.1e-83 281.1 0.2 3.3e-83 280.4 0.2 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Ribosomal_L50 PF10501.9 EMC93038.1 - 4.5e-19 68.6 0.0 7.6e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S ChAPs PF09295.10 EMC93042.1 - 1.7e-151 504.7 0.0 2.2e-151 504.4 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EMC93042.1 - 6.1e-05 23.5 4.3 0.23 12.0 0.0 3.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMC93042.1 - 0.00026 21.6 0.5 1.6 9.8 0.0 4.9 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC93042.1 - 0.0011 18.9 1.7 19 5.7 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat SOG2 PF10428.9 EMC93042.1 - 0.25 10.5 1.5 0.35 10.0 1.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TPR_11 PF13414.6 EMC93043.1 - 0.06 13.0 1.9 24 4.7 2.6 3.4 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 EMC93043.1 - 0.57 11.2 7.9 28 5.9 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3292 PF11696.8 EMC93045.1 - 1.4e-300 998.4 0.0 1.6e-300 998.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Profilin PF00235.19 EMC93045.1 - 3.2e-42 143.8 0.1 7.1e-42 142.7 0.1 1.6 1 0 0 1 1 1 1 Profilin RRM_1 PF00076.22 EMC93046.1 - 4.8e-13 48.7 0.0 5.2e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMC93046.1 - 0.022 14.3 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_like PF13242.6 EMC93048.1 - 6.1e-08 32.6 0.0 9.6e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EMC93048.1 - 0.019 15.0 0.0 0.061 13.4 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF676 PF05057.14 EMC93049.1 - 6.1e-40 137.1 0.0 7.1e-26 91.1 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) DUF1729 PF08354.10 EMC93050.1 - 2.2e-160 533.4 0.0 3.7e-160 532.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EMC93050.1 - 2e-87 293.7 0.1 2.6e-86 290.0 0.0 2.6 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 EMC93050.1 - 2.1e-50 170.3 0.0 6.3e-50 168.8 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 EMC93050.1 - 4.9e-40 137.8 0.0 1.7e-39 136.0 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EMC93050.1 - 7e-38 129.0 0.0 1.7e-37 127.7 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 EMC93050.1 - 1.8e-34 118.5 0.0 6.3e-34 116.8 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 EMC93050.1 - 9e-24 84.1 0.0 3.5e-23 82.2 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 EMC93050.1 - 0.063 12.6 0.3 1.5 8.2 0.3 2.6 2 1 0 2 2 2 0 Nitronate monooxygenase FAS_I_H PF18314.1 EMC93051.1 - 1.3e-78 263.3 0.2 3.4e-78 261.9 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EMC93051.1 - 2e-74 249.3 0.0 3.8e-74 248.4 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EMC93051.1 - 1.3e-20 74.1 0.0 2.5e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EMC93051.1 - 4.8e-18 65.4 0.0 1.1e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EMC93051.1 - 7.4e-11 42.1 0.0 2.5e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EMC93051.1 - 2e-06 27.4 0.6 6e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMC93051.1 - 0.0011 18.9 0.0 0.0032 17.4 0.0 1.8 1 0 0 1 1 1 1 KR domain Bac_rhamnosid6H PF17389.2 EMC93052.1 - 4.9e-09 35.9 0.0 7.8e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 EMC93052.1 - 0.00024 20.1 0.3 0.00035 19.5 0.3 1.1 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid_C PF17390.2 EMC93052.1 - 0.002 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 EMC93052.1 - 0.15 12.1 0.0 0.42 10.6 0.0 1.8 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain RCC1 PF00415.18 EMC93053.1 - 1.6e-58 195.1 4.6 7.6e-09 36.1 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMC93053.1 - 4e-33 112.5 31.7 5.4e-08 32.4 0.7 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.16 EMC93054.1 - 4.4e-20 71.9 84.2 9.7e-18 64.2 50.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 EMC93057.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2524 PF10732.9 EMC93058.1 - 0.0068 16.7 1.0 0.03 14.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2524) DUF2894 PF11445.8 EMC93058.1 - 0.04 14.4 0.6 0.059 13.8 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) Nic96 PF04097.14 EMC93060.1 - 1.4e-201 671.2 0.1 2.1e-201 670.7 0.1 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 EMC93060.1 - 4.8e-16 59.4 59.5 9.7e-12 45.6 27.6 4.4 2 1 2 4 4 4 3 Nucleoporin FG repeat region Amidase PF01425.21 EMC93063.1 - 8.4e-119 397.5 0.1 1e-118 397.2 0.1 1.0 1 0 0 1 1 1 1 Amidase DUF1180 PF06679.12 EMC93064.1 - 0.86 10.0 5.4 0.93 9.9 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Y_phosphatase PF00102.27 EMC93065.1 - 2.1e-54 184.6 0.2 8.6e-52 176.0 0.1 3.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EMC93065.1 - 4.4e-10 40.0 0.0 1.3e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 EMC93065.1 - 0.018 14.9 0.4 0.041 13.7 0.4 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EMC93065.1 - 0.026 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family TPR_19 PF14559.6 EMC93067.1 - 2.2e-10 40.9 1.3 3.4e-05 24.3 0.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMC93067.1 - 1.6e-06 28.3 3.1 0.0017 18.6 0.3 3.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMC93067.1 - 4.7e-05 23.8 0.4 0.4 11.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMC93067.1 - 0.00097 19.1 0.1 2.6 8.4 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMC93067.1 - 0.0016 19.0 5.0 0.037 14.7 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EMC93067.1 - 0.0035 17.0 0.3 0.13 11.9 0.1 2.4 1 1 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 EMC93067.1 - 0.017 15.5 0.4 1.9 9.1 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC93067.1 - 0.054 13.7 0.1 2.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EMC93067.1 - 0.087 13.5 1.9 95 4.1 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMC93067.1 - 2.1 9.4 9.2 13 6.9 0.1 4.9 2 1 3 5 5 5 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.18 EMC93068.1 - 1.1e-55 187.9 0.1 4.4e-55 185.9 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMC93068.1 - 1.6e-46 157.9 0.3 2e-44 151.1 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMC93068.1 - 6.6e-41 139.3 0.3 1.7e-40 137.9 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EMC93068.1 - 0.019 14.7 0.8 0.029 14.1 0.0 1.6 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Ustilago_mating PF05722.12 EMC93070.1 - 0.039 13.5 1.0 0.046 13.2 1.0 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Auto_anti-p27 PF06677.12 EMC93070.1 - 0.11 12.7 0.2 0.24 11.6 0.2 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ECSCR PF15820.5 EMC93071.1 - 6.4 6.7 5.9 0.7 9.7 0.2 2.1 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator RraA-like PF03737.15 EMC93072.1 - 3.3e-33 115.0 0.0 4.1e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA zinc_ribbon_10 PF10058.9 EMC93073.1 - 2.5e-20 71.9 0.2 4.4e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Cep57_CLD_2 PF14197.6 EMC93073.1 - 0.082 13.0 0.1 0.082 13.0 0.1 2.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Ima1_N PF09779.9 EMC93073.1 - 0.2 12.5 3.1 0.48 11.3 0.4 2.5 1 1 1 2 2 2 0 Ima1 N-terminal domain Rubredoxin_2 PF18073.1 EMC93073.1 - 2.5 7.9 9.3 0.25 11.1 3.0 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Haem_degrading PF03928.14 EMC93074.1 - 2.6e-31 108.1 0.3 3e-31 107.9 0.3 1.0 1 0 0 1 1 1 1 Haem-degrading HET PF06985.11 EMC93075.1 - 2.5e-24 86.3 0.0 4.3e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_97 PF10566.9 EMC93076.1 - 8.1e-50 169.7 0.0 1.1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 GH97_N PF14508.6 EMC93076.1 - 5.1e-25 88.3 0.0 8.1e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl-hydrolase 97 N-terminal GH97_C PF14509.6 EMC93076.1 - 2.6e-10 40.4 0.0 9.7e-09 35.3 0.0 2.5 1 1 0 1 1 1 1 Glycosyl-hydrolase 97 C-terminal, oligomerisation DASH_Duo1 PF08651.10 EMC93078.1 - 6.4e-31 106.0 2.5 9.9e-31 105.4 2.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF745 PF05335.13 EMC93078.1 - 0.0094 15.7 6.3 0.0094 15.7 6.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF745) HSM3_N PF18795.1 EMC93078.1 - 0.018 14.5 0.1 0.026 14.0 0.1 1.1 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain DASH_Dad2 PF08654.10 EMC93078.1 - 0.49 10.9 10.2 0.46 10.9 8.2 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad2 Spt5_N PF11942.8 EMC93078.1 - 1.7 9.7 14.4 3.1 8.9 0.9 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Exonuc_VII_L PF02601.15 EMC93078.1 - 8.3 5.9 13.6 10 5.6 13.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dermcidin PF15291.6 EMC93079.1 - 0.0089 16.6 0.4 0.011 16.2 0.4 1.1 1 0 0 1 1 1 1 Dermcidin, antibiotic peptide MFS_1 PF07690.16 EMC93083.1 - 3.3e-27 95.3 28.9 3.3e-27 95.3 28.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxysterol_BP PF01237.18 EMC93084.1 - 8.9e-64 215.6 5.1 1.2e-61 208.6 5.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3445 PF11927.8 EMC93086.1 - 9e-80 267.5 0.0 1e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Aminotran_5 PF00266.19 EMC93087.1 - 2.5e-19 69.5 0.0 3.4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMC93087.1 - 0.0018 17.6 0.1 0.0058 16.0 0.1 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EMC93087.1 - 0.0021 16.7 0.0 0.0039 15.8 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF480 PF04337.12 EMC93088.1 - 0.2 11.8 5.8 7.5 6.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF480 TFIIA PF03153.13 EMC93088.1 - 0.23 11.4 14.2 0.27 11.2 14.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 EMC93088.1 - 0.75 8.7 21.6 1 8.3 21.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Snf7 PF03357.21 EMC93089.1 - 3.5e-13 49.5 13.6 4.5e-13 49.2 13.6 1.1 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 EMC93089.1 - 0.0047 16.6 0.3 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase Ist1 PF03398.14 EMC93089.1 - 0.028 14.3 3.9 0.05 13.5 3.9 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Pkinase_fungal PF17667.1 EMC93089.1 - 0.059 12.1 1.6 0.067 11.9 1.6 1.2 1 0 0 1 1 1 0 Fungal protein kinase YojJ PF10372.9 EMC93089.1 - 0.23 11.6 1.2 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Fes1 PF08609.10 EMC93089.1 - 2.6 9.0 11.7 17 6.4 0.5 2.8 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 SLAC1 PF03595.17 EMC93090.1 - 3e-84 283.1 49.0 3.4e-84 282.9 49.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Brix PF04427.18 EMC93091.1 - 5.4e-43 147.4 0.0 7.4e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 EMC93091.1 - 2.6 7.3 23.1 13 5.0 18.5 2.3 2 0 0 2 2 2 0 BUD22 DEAD PF00270.29 EMC93092.1 - 3.5e-46 157.2 0.0 5.3e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC93092.1 - 5.3e-30 104.0 0.0 1.4e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC93092.1 - 2.3e-05 24.5 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HET PF06985.11 EMC93094.1 - 6.5e-19 68.7 0.0 7.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GDC-P PF02347.16 EMC93095.1 - 1.6e-180 600.6 0.0 2e-166 554.1 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EMC93095.1 - 8.5e-08 31.8 0.1 2.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Beta-eliminating lyase Glyco_hydro_65N PF03636.15 EMC93096.1 - 1.1e-36 126.6 0.0 2.2e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 EMC93096.1 - 2.7e-27 95.6 0.8 5.8e-26 91.2 0.3 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 EMC93096.1 - 0.00058 19.7 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 EMC93096.1 - 0.0013 18.8 0.2 0.005 16.9 0.2 2.1 1 0 0 1 1 1 1 F5/8 type C domain FAD_binding_3 PF01494.19 EMC93097.1 - 2.2e-26 93.0 0.2 3.3e-26 92.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC93097.1 - 1.6e-10 40.7 1.1 0.0001 21.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC93097.1 - 1.3e-08 34.9 6.8 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMC93097.1 - 1.4e-08 34.1 0.6 0.048 12.5 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase HI0933_like PF03486.14 EMC93097.1 - 9.6e-07 27.8 3.6 0.0022 16.8 2.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMC93097.1 - 7.2e-06 25.3 7.1 9.7e-06 24.9 2.4 2.5 1 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 EMC93097.1 - 2.2e-05 24.6 1.1 6.5e-05 23.1 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC93097.1 - 0.0011 19.4 1.1 0.093 13.3 0.6 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMC93097.1 - 0.0019 17.6 0.0 0.65 9.2 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EMC93097.1 - 0.0036 16.6 3.1 0.0058 15.9 1.8 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMC93097.1 - 0.0067 15.6 1.1 0.011 14.8 1.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMC93097.1 - 0.013 14.9 0.8 0.028 13.8 0.8 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMC93097.1 - 0.031 13.6 0.4 0.058 12.7 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EMC93097.1 - 0.057 13.1 0.5 0.14 11.8 0.5 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EMC93097.1 - 0.083 12.1 0.4 0.16 11.2 0.4 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EMC93097.1 - 0.28 10.2 1.6 7.6 5.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein cNMP_binding PF00027.29 EMC93099.1 - 8.3e-30 102.7 0.2 9.1e-18 64.1 0.0 5.2 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 EMC93099.1 - 3.5e-18 66.5 2.5 1.5e-12 48.2 0.7 2.9 3 0 0 3 3 3 2 Patatin-like phospholipase Paf1 PF03985.13 EMC93100.1 - 1.7e-66 225.0 0.0 2.7e-66 224.4 0.0 1.2 1 1 0 1 1 1 1 Paf1 ATP_sub_h PF10775.9 EMC93100.1 - 0.044 13.8 0.1 0.044 13.8 0.1 2.0 2 0 0 2 2 2 0 ATP synthase complex subunit h zf-primase PF09329.11 EMC93101.1 - 6.2e-18 64.3 0.4 1.2e-17 63.5 0.4 1.5 1 0 0 1 1 1 1 Primase zinc finger Cwf_Cwc_15 PF04889.12 EMC93101.1 - 0.014 15.2 0.4 0.014 15.2 0.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TMEM247 PF15444.6 EMC93101.1 - 0.086 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 RNase_H2-Ydr279 PF09468.10 EMC93102.1 - 2.6e-25 89.5 0.1 2.1e-24 86.5 0.0 2.1 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EMC93102.1 - 2.2e-22 79.1 0.0 4.6e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain TTL PF03133.15 EMC93103.1 - 4.4e-55 186.9 0.0 6.2e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EMC93103.1 - 3.6e-05 23.1 0.0 0.00011 21.6 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 EMC93103.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Actin PF00022.19 EMC93104.1 - 5.9e-91 305.1 0.0 2.9e-89 299.5 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 EMC93104.1 - 0.045 14.2 0.0 0.12 12.8 0.0 1.9 1 1 0 1 1 1 0 Cell division protein FtsA PPR_2 PF13041.6 EMC93107.1 - 2.1e-20 72.6 0.2 1.8e-15 56.9 0.0 4.8 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.20 EMC93107.1 - 1.5e-07 31.1 0.4 2.4e-05 24.3 0.0 4.0 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 EMC93107.1 - 2.1e-05 24.0 0.0 0.0046 16.4 0.0 3.0 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EMC93107.1 - 0.00011 22.2 0.0 0.88 9.7 0.0 3.7 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EMC93107.1 - 0.00024 20.7 0.0 0.04 13.6 0.0 3.7 3 0 0 3 3 3 1 PPR repeat MRP-S27 PF10037.9 EMC93107.1 - 0.041 12.7 0.1 4 6.2 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Kinesin PF00225.23 EMC93108.1 - 4.3e-62 210.0 0.0 5.8e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMC93108.1 - 2e-10 40.8 0.1 2.3e-07 30.8 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding LprI PF07007.12 EMC93108.1 - 0.0013 19.4 7.0 0.0034 18.0 7.0 1.7 1 0 0 1 1 1 1 Lysozyme inhibitor LprI AAA_33 PF13671.6 EMC93108.1 - 1.5 9.0 5.5 0.68 10.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain AIPR PF10592.9 EMC93110.1 - 0.015 15.0 0.1 0.016 14.8 0.1 1.0 1 0 0 1 1 1 0 AIPR protein AAA_12 PF13087.6 EMC93114.1 - 3.1e-07 30.2 0.0 3.9e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMC93115.1 - 4.2e-05 23.5 0.0 5.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMC93115.1 - 6.3e-05 22.8 0.0 8.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EMC93115.1 - 0.00041 20.2 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 Helicase FtsK_SpoIIIE PF01580.18 EMC93115.1 - 0.0094 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.6 EMC93115.1 - 0.047 14.0 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EMC93115.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EMC93115.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TENA_THI-4 PF03070.16 EMC93117.1 - 0.053 13.3 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family DUF2434 PF10361.9 EMC93118.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) SHS2_Rpb7-N PF03876.17 EMC93119.1 - 5.3e-13 49.2 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EMC93119.1 - 1.6e-08 34.8 0.1 2.5e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EMC93119.1 - 0.00061 20.0 0.0 0.0068 16.6 0.0 2.2 2 1 1 3 3 3 1 RNA polymerase III subunit Rpc25 Amnionless PF14828.6 EMC93121.1 - 0.14 11.0 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 Amnionless SOG2 PF10428.9 EMC93121.1 - 0.55 9.4 23.9 0.79 8.8 23.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein KAR9 PF08580.10 EMC93121.1 - 0.74 8.3 17.6 1 7.8 17.6 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SIMPL PF04402.14 EMC93126.1 - 0.59 10.6 5.9 1.3 9.4 5.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Coiled-coil_56 PF09813.9 EMC93127.1 - 0.00017 21.6 0.0 0.00021 21.3 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 EMC93128.1 - 2.9e-66 223.4 0.2 4.3e-66 222.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) AAA_25 PF13481.6 EMC93128.1 - 0.02 14.5 0.0 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Methyltransf_23 PF13489.6 EMC93131.1 - 3.4e-12 46.5 0.0 7.3e-12 45.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC93131.1 - 3.6e-07 30.8 0.1 0.018 15.7 0.2 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EMC93131.1 - 1.7e-05 25.5 0.1 0.00063 20.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC93131.1 - 8.5e-05 23.1 0.0 0.0019 18.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC93131.1 - 0.00034 20.4 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain FtsJ PF01728.19 EMC93131.1 - 0.0055 16.8 0.0 0.044 13.9 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 EMC93133.1 - 2.5e-19 69.7 0.0 4.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC93133.1 - 2.6e-18 66.5 0.0 4.9e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC93133.1 - 1.1e-11 44.8 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC93133.1 - 9e-10 39.2 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC93133.1 - 1.4e-08 34.7 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC93133.1 - 2.4e-07 30.3 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMC93133.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 EMC93133.1 - 0.027 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_2 PF00891.18 EMC93133.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 EMC93133.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.6 EMC93133.1 - 0.077 14.0 0.0 0.34 12.0 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain PCMT PF01135.19 EMC93133.1 - 0.12 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EMC93133.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase RuvX PF03652.15 EMC93134.1 - 0.17 12.3 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction resolvase Glyco_hydro_2_N PF02837.18 EMC93135.1 - 2.9e-13 50.1 0.1 8.7e-13 48.5 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EMC93135.1 - 8.8e-11 41.5 0.0 1.1e-08 34.6 0.0 2.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EMC93135.1 - 6.7e-08 33.2 0.0 1.4e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Csm1 PF12539.8 EMC93136.1 - 1.4e-32 112.1 0.0 3.8e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Filament PF00038.21 EMC93136.1 - 0.0021 17.7 9.9 0.0021 17.7 9.9 1.5 2 0 0 2 2 2 1 Intermediate filament protein Bap31_Bap29_C PF18035.1 EMC93136.1 - 0.014 15.4 9.3 0.16 12.0 1.8 3.3 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Rootletin PF15035.6 EMC93136.1 - 0.02 15.0 12.1 0.047 13.7 12.1 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2407_C PF13373.6 EMC93136.1 - 0.024 14.8 0.3 0.059 13.5 0.3 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain Prominin PF05478.11 EMC93136.1 - 0.039 11.9 10.3 0.051 11.5 10.3 1.1 1 0 0 1 1 1 0 Prominin RasGAP_C PF03836.15 EMC93136.1 - 0.091 12.9 5.1 0.11 12.6 4.2 1.6 1 1 0 1 1 1 0 RasGAP C-terminus Spc7 PF08317.11 EMC93136.1 - 0.29 10.0 17.2 0.78 8.6 16.8 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein JIP_LZII PF16471.5 EMC93136.1 - 0.31 11.2 9.4 0.041 14.0 3.5 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II HAUS-augmin3 PF14932.6 EMC93136.1 - 0.48 10.0 12.7 0.83 9.2 12.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TetR PF13972.6 EMC93136.1 - 0.48 10.1 3.8 1.5 8.5 0.4 2.3 2 0 0 2 2 2 0 Bacterial transcriptional repressor CENP-F_leu_zip PF10473.9 EMC93136.1 - 0.49 10.4 13.9 0.2 11.7 10.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.12 EMC93136.1 - 0.58 8.6 3.8 0.85 8.1 3.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 EMC93136.1 - 0.69 10.6 12.1 0.1 13.2 2.7 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Spc24 PF08286.11 EMC93136.1 - 0.72 10.1 15.6 0.38 11.0 3.2 3.4 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 FAM76 PF16046.5 EMC93136.1 - 0.83 9.0 12.5 0.023 14.0 5.3 1.9 2 0 0 2 2 2 0 FAM76 protein Mod_r PF07200.13 EMC93136.1 - 0.92 9.6 15.0 0.09 12.9 5.2 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein STAT_alpha PF01017.20 EMC93136.1 - 1.1 9.1 9.5 7.4 6.4 9.6 2.0 1 1 0 1 1 1 0 STAT protein, all-alpha domain V_ATPase_I PF01496.19 EMC93136.1 - 1.1 7.1 8.1 2.1 6.2 8.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 EMC93136.1 - 1.2 9.5 16.0 0.55 10.6 4.1 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain Jnk-SapK_ap_N PF09744.9 EMC93136.1 - 2.4 8.3 15.2 2.1 8.6 4.0 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 EMC93136.1 - 2.5 8.2 19.0 4.4 7.4 16.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 EMC93136.1 - 3.9 7.9 12.8 3.4 8.0 2.1 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 EMC93136.1 - 5.3 7.3 23.6 0.46 10.7 5.0 3.4 3 1 1 4 4 3 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 EMC93136.1 - 5.8 5.7 4.6 7.4 5.3 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Lectin_N PF03954.14 EMC93136.1 - 7.4 6.3 6.9 4.4 7.1 3.9 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF5094 PF17015.5 EMC93136.1 - 8.4 6.5 0.0 8.4 6.5 0.0 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF5094) GGACT PF06094.12 EMC93137.1 - 2.9e-07 31.1 0.2 4e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EMC93137.1 - 3e-06 27.5 0.0 8e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 AIG2-like family ChaC PF04752.12 EMC93137.1 - 0.014 15.4 0.2 0.024 14.7 0.2 1.4 1 1 0 1 1 1 0 ChaC-like protein Abhydrolase_4 PF08386.10 EMC93137.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein IBR PF01485.21 EMC93138.1 - 0.0023 18.1 8.1 0.0023 18.1 8.1 4.6 3 2 2 5 5 5 2 IBR domain, a half RING-finger domain CUE PF02845.16 EMC93138.1 - 0.023 14.4 0.2 18 5.2 0.1 3.3 3 0 0 3 3 3 0 CUE domain KH_8 PF17903.1 EMC93139.1 - 3.5e-30 103.9 0.0 9.6e-30 102.5 0.0 1.8 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EMC93139.1 - 0.0031 17.3 0.0 0.011 15.5 0.0 2.0 1 1 1 2 2 2 1 KH domain CH_2 PF06294.11 EMC93139.1 - 0.053 13.7 0.2 5.9 7.1 0.1 2.4 2 0 0 2 2 2 0 CH-like domain in sperm protein DUF724 PF05266.14 EMC93140.1 - 0.26 11.1 0.1 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) SMP PF04927.12 EMC93141.1 - 4.4e-10 39.9 13.6 2.3e-05 24.8 0.1 3.4 3 0 0 3 3 3 2 Seed maturation protein Glyco_hydro_19 PF00182.19 EMC93141.1 - 0.015 15.2 0.0 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Chitinase class I BMFP PF04380.13 EMC93141.1 - 0.27 11.8 2.7 12 6.4 0.1 2.6 2 0 0 2 2 2 0 Membrane fusogenic activity Peptidase_M28 PF04389.17 EMC93142.1 - 1.4e-25 90.1 0.8 6.4e-25 88.0 0.8 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EMC93142.1 - 5.7e-05 22.9 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EMC93142.1 - 0.0018 17.4 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase PAN_4 PF14295.6 EMC93143.1 - 9.5e-06 25.4 0.2 2.5e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 PAN domain DUF2776 PF10951.8 EMC93143.1 - 0.01 15.1 1.2 0.01 15.1 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2776) Adeno_E3_CR2 PF02439.15 EMC93143.1 - 0.034 13.9 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EMC93143.1 - 0.1 12.0 2.7 0.25 10.8 2.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 EMC93143.1 - 0.1 13.5 0.0 0.23 12.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Apt1 PF10351.9 EMC93143.1 - 0.44 9.4 4.9 0.71 8.7 4.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 EMC93143.1 - 3 7.1 9.3 5.8 6.2 9.3 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PRKCSH PF07915.13 EMC93144.1 - 8.2e-16 58.8 2.3 1.3e-15 58.1 0.1 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EMC93144.1 - 0.004 16.9 0.0 0.08 12.6 0.0 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein TIP41 PF04176.13 EMC93147.1 - 4.5e-67 224.8 0.1 5.7e-67 224.5 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family AA_kinase PF00696.28 EMC93148.1 - 1.8e-39 135.8 1.0 2.5e-39 135.3 1.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EMC93148.1 - 3.6e-17 62.1 0.1 7.7e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 PUA domain HET PF06985.11 EMC93150.1 - 1.4e-31 109.8 1.2 2.2e-31 109.1 1.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sybindin PF04099.12 EMC93152.1 - 8.5e-46 155.4 0.0 1e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EMC93152.1 - 7.5e-05 22.9 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region UQ_con PF00179.26 EMC93153.1 - 7.4e-44 148.8 0.2 3.6e-29 101.2 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMC93153.1 - 2.6e-05 23.9 0.0 0.0037 16.9 0.0 2.5 2 0 0 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 EMC93153.1 - 0.005 16.7 0.0 0.035 14.0 0.0 2.2 2 0 0 2 2 2 1 UEV domain UFC1 PF08694.11 EMC93153.1 - 0.13 11.9 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Peptidase_S8 PF00082.22 EMC93156.1 - 3.9e-30 105.1 16.3 6.4e-30 104.4 16.1 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMC93156.1 - 0.0057 17.3 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Adhesin_P1_N PF18652.1 EMC93156.1 - 0.16 12.0 1.1 0.34 10.9 1.1 1.5 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain zf-C2H2 PF00096.26 EMC93157.1 - 0.019 15.4 3.3 6.8 7.4 0.2 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sina PF03145.16 EMC93157.1 - 0.088 12.7 0.5 0.21 11.5 0.5 1.6 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_4 PF13894.6 EMC93157.1 - 0.23 12.4 8.4 0.53 11.3 0.2 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger FAD_binding_3 PF01494.19 EMC93159.1 - 3.1e-19 69.4 1.0 4.4e-18 65.7 1.0 2.0 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EMC93159.1 - 3.7e-07 29.4 6.7 0.028 13.3 4.5 3.1 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EMC93159.1 - 1.9e-06 27.4 1.9 0.0019 17.5 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMC93159.1 - 1.5e-05 24.5 0.6 2.2e-05 24.0 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EMC93159.1 - 3e-05 23.8 15.0 0.0011 18.6 0.2 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC93159.1 - 3.8e-05 23.8 1.6 9.8e-05 22.5 1.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC93159.1 - 8.8e-05 23.0 1.4 0.0031 18.0 0.6 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMC93159.1 - 0.00037 19.7 0.5 0.0005 19.3 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EMC93159.1 - 0.00042 19.7 2.3 0.0093 15.3 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EMC93159.1 - 0.00089 18.1 7.6 0.029 13.1 6.5 2.1 2 0 0 2 2 2 1 HI0933-like protein Rossmann-like PF10727.9 EMC93159.1 - 0.0044 16.9 1.3 0.012 15.5 1.3 1.6 1 0 0 1 1 1 1 Rossmann-like domain NAD_binding_9 PF13454.6 EMC93159.1 - 0.045 13.7 3.2 0.92 9.5 3.2 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMC93159.1 - 0.2 10.9 5.8 17 4.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC93159.1 - 0.2 10.9 2.3 0.34 10.1 2.3 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EMC93159.1 - 0.28 10.2 10.5 0.17 11.0 8.4 1.7 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 EMC93163.1 - 4e-42 144.4 44.4 4e-42 144.4 44.4 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC93163.1 - 8.7e-12 44.6 9.6 8.7e-12 44.6 9.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMC93163.1 - 2.8e-09 35.9 22.0 3.8e-09 35.5 22.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EMC93163.1 - 1.1e-05 24.9 6.8 1.1e-05 24.9 6.8 2.5 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PUCC PF03209.15 EMC93163.1 - 0.044 12.8 25.2 0.25 10.3 8.7 2.4 2 0 0 2 2 2 0 PUCC protein OATP PF03137.20 EMC93163.1 - 0.17 10.1 11.3 0.092 11.0 2.1 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PCI PF01399.27 EMC93164.1 - 1.5e-15 57.6 0.0 6.3e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 EMC93164.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 EMC93164.1 - 0.027 15.0 0.1 8.6 6.9 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TFIIF_beta_N PF17683.1 EMC93165.1 - 3.3e-30 105.5 0.4 5.2e-30 104.9 0.4 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EMC93165.1 - 6.5e-29 99.9 0.2 1.2e-28 99.0 0.2 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 EMC93165.1 - 0.0024 18.7 0.1 0.005 17.7 0.1 1.8 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Cys_Met_Meta_PP PF01053.20 EMC93166.1 - 2.9e-137 457.3 0.0 3.3e-137 457.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMC93166.1 - 1.7e-07 30.7 0.0 3.5e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMC93166.1 - 2.2e-05 23.9 0.1 5.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EMC93166.1 - 0.00022 20.3 0.0 0.00039 19.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V TPP_enzyme_N PF02776.18 EMC93167.1 - 2.8e-43 147.5 0.9 8.6e-43 145.9 1.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMC93167.1 - 2.3e-37 128.2 1.1 1.1e-36 125.9 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMC93167.1 - 8.7e-24 83.8 0.0 1.7e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain UPF0029 PF01205.19 EMC93168.1 - 3.5e-21 75.5 0.7 1.5e-20 73.5 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 VWA_2 PF13519.6 EMC93169.1 - 5.8e-24 84.8 0.7 1.6e-23 83.4 0.0 2.0 2 1 1 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 EMC93169.1 - 5.9e-08 32.8 0.0 8e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 EMC93169.1 - 1.8e-06 28.3 0.1 2.8e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 EMC93169.1 - 0.11 12.4 0.3 0.11 12.4 0.3 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif Dynein_heavy PF03028.15 EMC93169.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain WRNPLPNID PF15017.6 EMC93169.1 - 6.7 7.7 6.9 3.1 8.7 1.0 2.4 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Nbl1_Borealin_N PF10444.9 EMC93170.1 - 0.0012 18.4 0.4 0.002 17.7 0.4 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal AAL_decarboxy PF03306.13 EMC93172.1 - 5e-80 267.9 0.2 5.6e-80 267.8 0.2 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase BTB PF00651.31 EMC93175.1 - 0.0031 17.7 0.0 0.015 15.5 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain Tannase PF07519.11 EMC93175.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase PAN_4 PF14295.6 EMC93176.1 - 0.0036 17.2 1.0 0.0036 17.2 1.0 1.5 2 0 0 2 2 2 1 PAN domain HATPase_c PF02518.26 EMC93177.1 - 8.7e-28 97.1 0.0 2.5e-27 95.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMC93177.1 - 3e-23 82.1 0.5 6e-23 81.2 0.5 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 EMC93177.1 - 3.3e-17 62.7 0.0 1.4e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EMC93177.1 - 5.1e-17 62.0 0.1 2.5e-12 47.0 0.0 3.1 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 EMC93177.1 - 2.9e-16 59.5 0.0 2.5e-07 30.7 0.0 3.1 2 1 2 4 4 4 2 PAS fold HisKA PF00512.25 EMC93177.1 - 3.9e-16 58.8 1.2 8.7e-16 57.7 0.3 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_10 PF13596.6 EMC93177.1 - 0.0031 18.1 0.0 0.086 13.4 0.0 2.5 2 0 0 2 2 2 1 PAS domain Sulfotransfer_4 PF17784.1 EMC93178.1 - 4e-61 206.6 0.0 4.9e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain DAO PF01266.24 EMC93179.1 - 5.5e-37 128.2 0.2 7.3e-37 127.7 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 EMC93179.1 - 8e-11 41.7 0.1 2e-09 37.3 0.0 2.9 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 EMC93179.1 - 2e-06 27.9 0.4 5.1e-06 26.6 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMC93179.1 - 2.4e-05 23.9 0.7 0.0026 17.2 0.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC93179.1 - 7e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC93179.1 - 0.00012 21.5 0.1 0.00018 20.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EMC93179.1 - 0.0014 18.0 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC93179.1 - 0.0022 17.1 0.1 0.0033 16.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EMC93179.1 - 0.0052 17.3 0.2 0.012 16.2 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC93179.1 - 0.0099 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EMC93179.1 - 0.097 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 EMC93179.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EMC93179.1 - 0.12 11.4 0.1 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A An_peroxidase PF03098.15 EMC93180.1 - 2.6e-120 402.5 0.0 3.1e-120 402.2 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Peroxidase_2 PF01328.17 EMC93181.1 - 9.3e-41 140.4 0.0 1.2e-40 140.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 3Beta_HSD PF01073.19 EMC93182.1 - 1.7e-53 181.5 0.0 2.2e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMC93182.1 - 3.8e-28 98.6 0.0 6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC93182.1 - 3.3e-18 66.2 0.3 2.7e-15 56.6 0.3 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMC93182.1 - 1.2e-11 44.3 0.0 2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EMC93182.1 - 2.4e-11 43.3 0.3 4.1e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EMC93182.1 - 4.4e-07 29.3 0.7 5.2e-06 25.8 0.7 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMC93182.1 - 5.7e-07 29.6 0.0 9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMC93182.1 - 1.2e-05 25.3 0.6 0.00017 21.6 0.6 2.2 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EMC93182.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family adh_short PF00106.25 EMC93182.1 - 0.025 14.0 0.0 0.052 13.0 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase FtsJ PF01728.19 EMC93182.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase HECT_2 PF09814.9 EMC93183.1 - 4.9e-54 183.6 0.0 5.5e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding KorB_C PF06613.11 EMC93184.1 - 0.16 12.0 0.1 0.43 10.6 0.1 1.7 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain zf-C2H2 PF00096.26 EMC93185.1 - 0.00014 22.1 5.6 0.00014 22.1 5.6 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EMC93185.1 - 0.0014 18.3 12.9 0.0091 15.7 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EMC93185.1 - 0.0035 17.3 1.0 0.0073 16.3 1.0 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EMC93185.1 - 0.0044 17.7 3.7 0.0044 17.7 3.7 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMC93185.1 - 1.1 9.8 16.8 0.47 11.0 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger double domain TGT PF01702.18 EMC93187.1 - 2.2e-139 464.5 0.0 2.6e-139 464.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Importin_rep_5 PF18816.1 EMC93188.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Importin repeat UBA PF00627.31 EMC93189.1 - 7.2e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 EMC93189.1 - 9.4e-07 28.5 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.6 EMC93189.1 - 0.002 17.9 0.1 0.0039 17.0 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBA_3 PF09288.10 EMC93189.1 - 0.0062 16.3 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain PRO8NT PF08082.11 EMC93189.1 - 0.023 14.6 1.3 0.035 14.0 1.3 1.2 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain YukD PF08817.10 EMC93189.1 - 0.056 14.1 0.1 0.36 11.6 0.0 2.3 2 1 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 EMC93189.1 - 0.084 12.7 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like NOG1_N PF17835.1 EMC93191.1 - 1.2e-47 161.8 0.0 1.2e-47 161.8 0.0 2.2 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EMC93191.1 - 8.3e-26 89.5 0.3 1.7e-25 88.5 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EMC93191.1 - 9.8e-26 89.5 3.1 2.6e-25 88.1 3.1 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EMC93191.1 - 1.1e-14 54.5 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMC93191.1 - 1.3e-07 31.2 0.0 2.7e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMC93191.1 - 0.0021 18.0 0.1 0.88 9.5 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 EMC93191.1 - 0.0032 16.9 0.1 0.0055 16.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 EMC93191.1 - 0.051 14.1 0.3 0.27 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMC93191.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.7 2 2 0 2 2 1 0 AAA ATPase domain Dynamin_N PF00350.23 EMC93191.1 - 0.31 11.1 7.4 3.8 7.5 0.0 3.1 3 1 1 4 4 4 0 Dynamin family DUF4407 PF14362.6 EMC93191.1 - 1.2 8.4 14.8 2.1 7.6 14.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_18 PF00704.28 EMC93193.1 - 3.4e-12 46.7 0.8 4.8e-12 46.2 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HLH PF00010.26 EMC93194.1 - 4e-15 55.5 0.7 9.2e-15 54.3 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4164 PF13747.6 EMC93194.1 - 0.12 12.6 0.6 0.34 11.2 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) UAA PF08449.11 EMC93195.1 - 6.6e-82 275.1 12.1 9.3e-82 274.6 12.1 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EMC93195.1 - 2e-06 27.2 0.3 2e-06 27.2 0.3 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter CRT-like PF08627.10 EMC93195.1 - 0.0057 15.6 0.6 0.0057 15.6 0.6 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like PikAIV_N PF18605.1 EMC93195.1 - 0.13 11.9 0.5 0.22 11.1 0.5 1.4 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain LapA_dom PF06305.11 EMC93195.1 - 0.28 11.0 1.9 0.76 9.6 0.1 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain EamA PF00892.20 EMC93195.1 - 6.3 7.0 28.6 6 7.0 5.9 3.5 2 2 1 3 3 3 0 EamA-like transporter family MS_channel PF00924.18 EMC93196.1 - 1.7e-22 80.0 1.2 2.6e-22 79.4 1.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 EMC93196.1 - 6.1e-05 22.3 0.0 0.00016 21.0 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EMC93196.1 - 0.00058 19.2 0.3 0.0013 18.1 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EMC93196.1 - 0.0014 18.4 0.0 0.0038 17.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EMC93196.1 - 0.0037 17.7 0.2 0.0089 16.5 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair Macoilin PF09726.9 EMC93196.1 - 0.38 9.3 2.3 0.6 8.6 2.3 1.2 1 0 0 1 1 1 0 Macoilin family Hva1_TUDOR PF11160.8 EMC93198.1 - 2.1e-16 59.8 0.3 2.1e-16 59.8 0.3 3.0 2 1 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Cyclin PF08613.11 EMC93199.1 - 4.6e-30 105.1 0.0 5.5e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EMC93199.1 - 8e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain HTH_3 PF01381.22 EMC93199.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix PWI PF01480.17 EMC93203.1 - 3e-07 30.6 0.0 5.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EMC93203.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S21 PF01165.20 EMC93204.1 - 4.1e-14 52.0 5.8 7.2e-14 51.2 5.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 TENA_THI-4 PF03070.16 EMC93205.1 - 6.8e-07 29.3 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Amidoligase_2 PF12224.8 EMC93206.1 - 1.2e-16 61.1 0.2 1.5e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme Fungal_trans PF04082.18 EMC93207.1 - 8.7e-30 103.6 0.0 1.9e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93207.1 - 1.6e-07 31.3 8.2 2.6e-07 30.7 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SARAF PF06682.12 EMC93207.1 - 5.6 6.5 13.6 0.05 13.2 1.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2781 PF10914.8 EMC93208.1 - 3.3e-42 144.4 13.1 3.8e-42 144.2 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) zf-C2H2 PF00096.26 EMC93209.1 - 4.6e-05 23.6 29.2 0.00038 20.8 3.1 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC93209.1 - 8.1e-05 23.1 22.8 0.13 13.2 2.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger Chorion_2 PF03964.15 EMC93209.1 - 0.011 16.5 5.5 2.5 9.0 2.6 2.5 2 0 0 2 2 2 0 Chorion family 2 zf-MYST PF17772.1 EMC93209.1 - 2.9 7.6 4.6 0.5 10.0 0.6 1.8 2 0 0 2 2 2 0 MYST family zinc finger domain SR-25 PF10500.9 EMC93209.1 - 3.2 7.3 13.1 0.57 9.8 5.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-C2H2_6 PF13912.6 EMC93209.1 - 4.5 7.4 19.5 2.4 8.3 2.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMC93209.1 - 5.4 7.6 22.3 4.1 8.0 4.5 4.3 4 0 0 4 4 4 0 Zinc-finger double domain Lipase_GDSL PF00657.22 EMC93212.1 - 2e-12 47.5 0.0 2.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EMC93212.1 - 8.1e-06 26.3 5.1 3.7e-05 24.2 5.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pro_isomerase PF00160.21 EMC93213.1 - 1.6e-46 158.4 0.0 1.8e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPT2 PF08243.11 EMC93214.1 - 9.7e-09 35.7 16.8 9.7e-09 35.7 16.8 2.2 2 0 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 EMC93215.1 - 4.3e-24 84.9 20.6 1.3e-22 80.2 20.6 2.0 1 1 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.21 EMC93216.1 - 1.9e-31 107.8 0.4 2.2e-31 107.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DPPIV_N PF00930.21 EMC93217.1 - 2.3e-106 355.5 0.5 3e-106 355.2 0.5 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EMC93217.1 - 7.9e-52 175.8 3.5 1.5e-51 174.9 3.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EMC93217.1 - 7.3e-05 22.5 2.5 0.00018 21.2 1.8 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EMC93217.1 - 0.0034 17.1 0.4 0.018 14.7 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC93217.1 - 0.013 14.8 0.5 0.18 11.0 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 EMC93217.1 - 0.047 13.2 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EMC93217.1 - 0.056 13.2 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EMC93217.1 - 0.12 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PD40 PF07676.12 EMC93217.1 - 0.21 11.5 8.3 10 6.2 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat p450 PF00067.22 EMC93219.1 - 6.4e-10 38.4 0.0 6.8e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Isochorismatase PF00857.20 EMC93220.1 - 5.5e-27 95.1 0.0 2.1e-26 93.1 0.0 2.0 2 1 0 2 2 2 1 Isochorismatase family DnaJ_C PF01556.18 EMC93221.1 - 9.6e-38 129.6 0.1 1.3e-37 129.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMC93221.1 - 1.3e-21 76.4 0.7 2.1e-21 75.8 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMC93221.1 - 4.6e-09 36.5 21.7 8.8e-09 35.6 21.7 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EMC93221.1 - 6.8 6.7 8.3 68 3.5 8.3 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA BRO1 PF03097.18 EMC93222.1 - 2.3e-134 448.1 5.0 2.3e-134 448.1 5.0 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EMC93222.1 - 5.4e-81 272.1 17.9 5.4e-81 272.1 17.9 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV GCP_N_terminal PF17681.1 EMC93222.1 - 0.024 14.3 2.1 0.058 13.0 2.1 1.6 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Takusan PF04822.13 EMC93222.1 - 0.17 11.8 7.5 0.068 13.1 1.7 3.0 2 0 0 2 2 2 0 Takusan DUF416 PF04222.12 EMC93222.1 - 0.32 10.4 5.2 0.27 10.6 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF416) ADK PF00406.22 EMC93222.1 - 0.43 10.7 3.8 0.98 9.5 3.8 1.6 1 0 0 1 1 1 0 Adenylate kinase Cortex-I_coil PF09304.10 EMC93222.1 - 0.46 10.7 9.6 0.061 13.5 4.0 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil LysM PF01476.20 EMC93223.1 - 0.00014 21.8 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 LysM domain FAD_binding_2 PF00890.24 EMC93224.1 - 3.2e-114 382.2 3.1 4.4e-114 381.8 3.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EMC93224.1 - 4.8e-39 133.3 0.3 7.2e-39 132.7 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EMC93224.1 - 0.00012 21.4 2.3 0.0024 17.1 0.5 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMC93224.1 - 0.00015 21.0 1.6 0.012 14.7 2.1 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 EMC93224.1 - 0.00035 19.9 0.7 0.079 12.2 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EMC93224.1 - 0.0039 16.5 0.5 0.0062 15.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMC93224.1 - 0.018 13.7 3.7 0.18 10.5 0.2 2.7 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 EMC93224.1 - 0.03 13.9 0.5 0.068 12.7 0.5 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMC93224.1 - 1.6 7.9 3.0 2 7.6 1.7 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amdase PF17645.1 EMC93226.1 - 5.7e-15 55.5 0.0 7.8e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 EMC93226.1 - 9.9e-06 25.6 0.0 1.8e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Sds3 PF08598.11 EMC93227.1 - 6.6e-18 65.5 4.3 1.6e-17 64.3 4.3 1.6 1 0 0 1 1 1 1 Sds3-like PEP-utilisers_N PF05524.13 EMC93227.1 - 5.6 7.2 6.7 33 4.7 0.2 3.4 4 0 0 4 4 4 0 PEP-utilising enzyme, N-terminal RRM_1 PF00076.22 EMC93228.1 - 1.7e-11 43.8 0.8 7.8e-10 38.4 0.0 3.5 5 0 0 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3619 PF12279.8 EMC93228.1 - 3.5 8.0 7.8 1.9 8.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) PMT PF02366.18 EMC93229.1 - 1e-83 280.7 17.8 1.6e-83 280.0 17.8 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMC93229.1 - 5.4e-69 231.8 4.6 5.4e-69 231.8 4.6 3.3 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMC93229.1 - 2.7e-16 59.9 0.1 4.8e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EMC93229.1 - 0.00039 20.7 8.2 0.00039 20.7 8.2 3.2 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Epimerase PF01370.21 EMC93230.1 - 1.9e-12 47.1 0.1 4.3e-12 46.0 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMC93230.1 - 8.4e-12 44.7 0.0 1.7e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMC93230.1 - 2.4e-10 40.6 0.1 4.3e-10 39.8 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMC93230.1 - 2.4e-08 33.5 0.0 7.2e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 EMC93230.1 - 3.1e-07 30.2 0.1 7.4e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EMC93230.1 - 3.5e-06 26.6 0.0 8e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMC93230.1 - 8.6e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EMC93230.1 - 0.00012 22.0 0.4 0.28 11.1 0.1 2.4 2 0 0 2 2 2 2 KR domain adh_short PF00106.25 EMC93230.1 - 0.093 12.2 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase ATP-synt_ab PF00006.25 EMC93231.1 - 2.9e-74 249.3 0.0 4.1e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EMC93231.1 - 6.2e-48 162.3 0.9 1.1e-47 161.5 0.9 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EMC93231.1 - 2.8e-15 56.6 4.5 3.8e-15 56.2 3.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 EMC93231.1 - 0.14 12.4 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RbcS PF12338.8 EMC93231.1 - 9.5 6.5 8.3 2.7 8.3 0.4 3.3 3 0 0 3 3 3 0 Ribulose-1,5-bisphosphate carboxylase small subunit DUF962 PF06127.11 EMC93232.1 - 1.7e-25 88.9 1.7 2.7e-25 88.3 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Questin_oxidase PF14027.6 EMC93233.1 - 1.4e-92 310.9 4.1 1.6e-92 310.6 4.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like SlyX PF04102.12 EMC93234.1 - 0.0012 19.4 0.1 0.59 10.8 0.0 2.1 2 0 0 2 2 2 2 SlyX DUF948 PF06103.11 EMC93234.1 - 0.02 15.1 0.4 0.17 12.2 0.4 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 EMC93234.1 - 0.097 12.7 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNase_T PF00929.24 EMC93235.1 - 4.6e-06 27.3 0.0 2e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Exonuclease YqeY PF09424.10 EMC93236.1 - 1.3e-21 77.2 9.3 1.7e-21 76.8 9.3 1.1 1 0 0 1 1 1 1 Yqey-like protein CM_2 PF01817.21 EMC93236.1 - 0.0078 16.5 1.2 0.021 15.1 0.8 1.9 2 0 0 2 2 2 1 Chorismate mutase type II Nucleoporin_N PF08801.11 EMC93237.1 - 2.5e-75 253.9 0.0 3.7e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EMC93237.1 - 3.2e-50 171.5 1.1 4.6e-50 171.0 1.1 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal WD40 PF00400.32 EMC93238.1 - 4.2e-11 43.2 13.7 0.003 18.3 0.3 4.8 4 1 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EMC93238.1 - 0.024 13.6 0.2 2.5 7.0 0.0 3.0 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glycos_transf_4 PF00953.21 EMC93239.1 - 3.6e-32 111.6 10.0 3.6e-32 111.6 10.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF3318 PF11780.8 EMC93239.1 - 0.078 12.9 0.3 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) Glyco_hydro_71 PF03659.14 EMC93240.1 - 3.9e-104 348.5 12.0 4.6e-104 348.2 12.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Amidase PF01425.21 EMC93241.1 - 2.9e-51 174.9 0.1 7.3e-46 157.0 0.2 2.4 2 1 0 2 2 2 2 Amidase Aldolase_II PF00596.21 EMC93242.1 - 5.5e-48 163.4 0.0 7e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain R3H-assoc PF13902.6 EMC93243.1 - 1.1e-26 93.8 7.9 2.7e-26 92.5 7.9 1.6 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 EMC93243.1 - 0.0028 17.6 1.2 0.035 14.1 0.0 2.7 3 0 0 3 3 3 1 R3H domain Med9 PF07544.13 EMC93243.1 - 0.56 10.3 4.5 1.6 8.9 4.5 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Gly-zipper_YMGG PF13441.6 EMC93244.1 - 0.27 11.0 10.1 0.71 9.7 10.1 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EMC93244.1 - 3.3 7.8 10.3 8.8 6.4 10.3 1.7 1 0 0 1 1 1 0 Glycine zipper NUFIP1 PF10453.9 EMC93247.1 - 8.2e-10 38.4 2.0 2e-09 37.1 2.0 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 EMC93247.1 - 1.6e-05 24.8 6.3 2.5e-05 24.2 6.3 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EMC93247.1 - 3.1e-05 23.7 5.0 4.8e-05 23.1 5.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EMC93247.1 - 0.00023 20.9 3.3 0.00039 20.1 3.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 EMC93247.1 - 0.023 15.4 0.0 0.056 14.1 0.0 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 EMC93247.1 - 0.033 14.7 3.0 0.058 13.9 3.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF4349 PF14257.6 EMC93247.1 - 0.046 13.2 0.1 0.079 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) RNA_pol_Rbc25 PF08292.12 EMC93248.1 - 1.8e-26 92.9 0.2 2.8e-26 92.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EMC93248.1 - 1.3e-14 54.3 0.1 2e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 zf-GRF PF06839.12 EMC93250.1 - 5.4e-09 36.0 6.8 1.1e-08 35.0 5.5 2.0 2 0 0 2 2 2 1 GRF zinc finger Sox_N PF12444.8 EMC93250.1 - 0.0036 18.4 1.7 1.6 9.9 0.4 2.8 2 0 0 2 2 2 2 Sox developmental protein N terminal Cut12 PF11500.8 EMC93250.1 - 0.092 12.7 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Fungal_trans PF04082.18 EMC93251.1 - 1.1e-26 93.5 0.0 1.5e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93251.1 - 8.8e-05 22.5 18.1 0.00016 21.7 18.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EMC93252.1 - 1.6e-31 109.5 29.3 1.6e-31 109.5 29.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0154 PF03672.13 EMC93252.1 - 0.19 11.8 1.4 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DHDPS PF00701.22 EMC93253.1 - 3.9e-37 127.5 0.0 4.7e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 EMC93253.1 - 0.026 14.5 0.1 0.059 13.4 0.1 1.6 1 0 0 1 1 1 0 PA domain Ntox21 PF15526.6 EMC93254.1 - 0.18 12.1 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Novel toxin 21 MFS_1 PF07690.16 EMC93255.1 - 3.9e-45 154.3 39.1 3.9e-45 154.3 39.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC93255.1 - 1.8e-08 33.7 36.0 1.2e-06 27.7 36.0 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EMC93255.1 - 0.038 12.3 10.8 0.15 10.3 2.8 3.4 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MTP18 PF10558.9 EMC93256.1 - 7.9e-78 260.3 0.1 9.8e-78 260.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Rad51 PF08423.11 EMC93257.1 - 8.6e-08 31.8 0.0 2e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 EMC93257.1 - 6e-06 25.9 0.0 9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EMC93257.1 - 0.0039 16.8 0.9 0.016 14.8 0.1 2.2 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 EMC93257.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 KaiC MOSC PF03473.17 EMC93258.1 - 2.7e-29 101.8 0.0 4.5e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EMC93258.1 - 2.4e-12 46.8 0.0 4.2e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Peptidase_S8 PF00082.22 EMC93259.1 - 0.06 12.6 0.1 0.069 12.4 0.1 1.1 1 0 0 1 1 1 0 Subtilase family CBP_BcsR PF10945.8 EMC93260.1 - 0.053 13.0 0.2 0.099 12.1 0.2 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR PALP PF00291.25 EMC93261.1 - 4.7e-61 206.8 0.0 6.6e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EMC93261.1 - 3.1e-11 43.6 0.1 1.8e-08 34.7 0.0 2.8 2 0 0 2 2 2 2 CBS domain Zeta_toxin PF06414.12 EMC93261.1 - 0.045 13.0 0.0 0.14 11.4 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin NAD_binding_2 PF03446.15 EMC93262.1 - 3.2e-26 92.4 0.1 4.8e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMC93262.1 - 4.8e-09 36.5 0.0 7.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EMC93262.1 - 3.1e-07 30.5 0.0 5.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EMC93262.1 - 6.1e-05 23.5 0.3 0.0002 21.9 0.1 2.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EMC93262.1 - 0.0034 17.0 0.1 0.0089 15.6 0.1 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 EMC93262.1 - 0.0047 16.8 0.2 0.0068 16.3 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding OCD_Mu_crystall PF02423.15 EMC93262.1 - 0.0081 15.1 0.4 0.02 13.9 0.2 1.6 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family ADH_zinc_N PF00107.26 EMC93262.1 - 0.028 14.4 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FIST_C PF10442.9 EMC93262.1 - 0.1 12.6 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 FIST C domain ETC_C1_NDUFA5 PF04716.14 EMC93265.1 - 1.7e-22 79.0 0.1 2.1e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Thioredoxin PF00085.20 EMC93266.1 - 8.7e-45 150.9 0.0 4.1e-25 87.8 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EMC93266.1 - 3.9e-10 39.9 0.0 0.00026 21.0 0.0 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMC93266.1 - 9.1e-06 25.9 0.0 0.19 12.1 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 EMC93266.1 - 0.0011 18.4 0.0 0.98 8.7 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family HyaE PF07449.11 EMC93266.1 - 0.019 15.0 0.0 7.6 6.5 0.0 2.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 EMC93266.1 - 0.072 13.3 0.7 0.66 10.2 0.1 2.8 2 0 0 2 2 2 0 Thioredoxin-like CENP-O PF09496.10 EMC93266.1 - 0.32 11.0 2.7 0.53 10.2 2.7 1.3 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Rot1 PF10681.9 EMC93268.1 - 2.4e-97 324.5 0.1 2.8e-97 324.3 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YadA_anchor PF03895.15 EMC93268.1 - 0.19 11.8 0.9 6.2 7.0 0.3 2.6 2 0 0 2 2 2 0 YadA-like membrane anchor domain 5-FTHF_cyc-lig PF01812.20 EMC93269.1 - 5.8e-39 133.9 0.0 7e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.22 EMC93270.1 - 8.5e-16 57.4 0.0 1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EMC93270.1 - 0.00023 20.8 0.1 0.00031 20.3 0.1 1.2 1 0 0 1 1 1 1 Hfq protein PhnA PF03831.14 EMC93270.1 - 0.12 12.3 0.1 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 PhnA domain Xpo1 PF08389.12 EMC93271.1 - 1.9e-30 105.9 7.1 1.4e-29 103.1 2.0 3.7 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EMC93271.1 - 2.2e-08 33.9 0.6 7e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EMC93271.1 - 0.00011 22.5 0.1 0.0022 18.4 0.0 3.3 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 EMC93271.1 - 0.00028 21.3 0.3 0.005 17.3 0.0 3.5 3 0 0 3 3 2 1 HEAT-like repeat Importin_rep_3 PF18806.1 EMC93271.1 - 0.0023 18.0 0.2 5 7.3 0.0 4.2 4 0 0 4 4 4 1 Importin 13 repeat Adaptin_N PF01602.20 EMC93271.1 - 0.0041 15.7 0.5 0.081 11.5 0.2 2.3 2 0 0 2 2 2 1 Adaptin N terminal region DRIM PF07539.12 EMC93271.1 - 0.0058 15.0 0.7 0.012 14.0 0.7 1.5 1 0 0 1 1 1 1 Down-regulated in metastasis DSHCT PF08148.12 EMC93271.1 - 0.018 14.7 0.3 0.061 13.0 0.1 1.9 1 1 0 1 1 1 0 DSHCT (NUC185) domain HEAT PF02985.22 EMC93271.1 - 0.021 15.0 0.4 65 4.2 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat GAT PF03127.14 EMC93271.1 - 0.039 14.3 3.4 1.9 8.9 0.0 3.7 3 0 0 3 3 3 0 GAT domain Death PF00531.22 EMC93271.1 - 2.3 8.5 8.7 0.89 9.8 0.1 3.8 5 0 0 5 5 4 0 Death domain Sugar_tr PF00083.24 EMC93272.1 - 6.4e-87 292.3 27.0 7.4e-87 292.1 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC93272.1 - 1.4e-16 60.4 42.5 1.1e-11 44.3 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMC93272.1 - 2.2e-06 26.5 15.9 0.0019 16.9 3.3 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein zf-UBR PF02207.20 EMC93273.1 - 0.026 14.7 2.1 0.06 13.5 2.1 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Complex1_49kDa PF00346.19 EMC93273.1 - 0.24 10.4 0.7 0.38 9.8 0.7 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SAP30_Sin3_bdg PF13867.6 EMC93275.1 - 6.1e-05 23.3 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Ground-like PF04155.18 EMC93275.1 - 0.034 14.8 0.0 0.065 13.9 0.0 1.4 1 0 0 1 1 1 0 Ground-like domain Dynamin_M PF01031.20 EMC93276.1 - 3e-107 358.1 0.0 5.7e-107 357.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EMC93276.1 - 6.2e-57 192.3 0.1 2.1e-56 190.6 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EMC93276.1 - 6.5e-32 109.5 2.3 1.6e-31 108.3 2.3 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EMC93276.1 - 0.0001 22.4 0.2 0.00081 19.4 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3042 PF11240.8 EMC93276.1 - 6 7.0 6.0 13 5.9 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) PBP PF01161.20 EMC93277.1 - 4e-16 59.5 0.0 4.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein F-box PF00646.33 EMC93278.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain LSM PF01423.22 EMC93280.1 - 1.4e-16 59.9 1.1 4.3e-16 58.4 0.6 2.0 2 0 0 2 2 2 1 LSM domain Methyltransf_11 PF08241.12 EMC93280.1 - 1.9e-08 34.9 0.0 5.7e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC93280.1 - 0.003 18.2 0.0 0.0089 16.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Caudo_TAP PF02413.17 EMC93280.1 - 0.31 11.2 3.4 7 6.8 0.0 2.6 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Ribul_P_3_epim PF00834.19 EMC93281.1 - 6e-49 166.1 0.0 1.5e-47 161.6 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EMC93281.1 - 0.0075 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 EMC93281.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.17 EMC93281.1 - 0.073 12.5 0.5 0.35 10.3 0.5 1.9 1 1 0 1 1 1 0 PcrB family TAFII55_N PF04658.13 EMC93282.1 - 8.5e-52 175.1 0.2 1.6e-51 174.2 0.2 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region AAA_lid_9 PF17871.1 EMC93282.1 - 0.39 10.6 9.2 0.37 10.7 2.6 3.1 2 1 1 3 3 3 0 AAA lid domain Bromo_TP PF07524.13 EMC93283.1 - 4.7e-09 36.1 0.0 6.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EMC93283.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AA_permease_2 PF13520.6 EMC93285.1 - 1.4e-47 162.5 40.4 1.9e-47 162.1 40.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC93285.1 - 2.3e-22 79.3 36.3 4.2e-22 78.4 36.3 1.4 1 1 0 1 1 1 1 Amino acid permease adh_short PF00106.25 EMC93287.1 - 1.1e-27 96.8 0.3 1.6e-23 83.2 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93287.1 - 9.8e-17 61.3 0.4 3.9e-15 56.0 0.4 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC93287.1 - 3e-05 24.0 0.1 5.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMC93287.1 - 0.083 12.3 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FAD_binding_3 PF01494.19 EMC93288.1 - 3.3e-82 276.6 0.0 4.1e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC93288.1 - 0.09 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC93288.1 - 0.96 9.7 3.0 2.5 8.4 3.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain cobW PF02492.19 EMC93289.1 - 1.8e-47 161.2 0.1 2.6e-47 160.7 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EMC93289.1 - 2.2e-05 24.4 0.3 0.24 11.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 EMC93289.1 - 0.00067 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_23 PF13476.6 EMC93289.1 - 0.0011 19.5 0.7 0.002 18.6 0.1 1.7 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 EMC93289.1 - 0.0056 15.7 0.5 2.1 7.2 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EMC93289.1 - 0.0092 15.5 1.2 1.2 8.7 1.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EMC93289.1 - 0.017 15.6 0.0 0.19 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EMC93289.1 - 0.02 15.0 0.0 0.042 13.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EMC93289.1 - 0.02 15.3 0.1 0.076 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 EMC93289.1 - 0.04 13.9 0.4 0.12 12.4 0.2 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 EMC93289.1 - 0.056 12.7 0.2 9.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Septin ATPase_2 PF01637.18 EMC93289.1 - 0.059 13.3 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EMC93289.1 - 0.083 12.6 0.1 0.083 12.6 0.1 2.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EMC93289.1 - 0.084 12.6 0.1 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMC93289.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMC93289.1 - 0.12 12.9 2.5 0.18 12.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 EMC93289.1 - 0.12 12.3 0.0 0.33 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EMC93289.1 - 0.18 11.6 0.1 9.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PAS_3 PF08447.12 EMC93291.1 - 2.9e-09 37.1 0.0 8.7e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EMC93291.1 - 1.3e-06 28.6 0.0 1.4e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EMC93291.1 - 0.00024 21.3 0.0 0.44 10.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 EMC93291.1 - 0.00046 20.2 0.0 0.02 14.9 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 EMC93291.1 - 0.032 14.4 0.0 0.092 12.9 0.0 1.7 2 0 0 2 2 2 0 PAS domain WD40 PF00400.32 EMC93292.1 - 9.1e-18 64.3 4.1 5.7e-07 30.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC93292.1 - 4e-05 23.8 0.0 1.4 9.3 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EMC93292.1 - 0.005 16.7 0.0 0.11 12.5 0.0 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Mob1_phocein PF03637.17 EMC93293.1 - 9.3e-23 81.1 0.1 1.5e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family Neur_chan_memb PF02932.16 EMC93293.1 - 9 6.3 5.5 17 5.4 5.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HET PF06985.11 EMC93295.1 - 1.4e-11 44.9 0.0 1.6e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DEAD PF00270.29 EMC93299.1 - 5.9e-26 91.3 0.0 1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC93299.1 - 6.4e-12 45.8 0.1 2e-11 44.2 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 EMC93299.1 - 1.3e-11 45.1 0.0 3.9e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.11 EMC93299.1 - 1.1e-05 25.9 0.0 2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 EMC93299.1 - 3.7e-05 23.8 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mannosyl_trans3 PF11051.8 EMC93301.1 - 3e-54 184.3 0.0 3.1e-34 118.6 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Aa_trans PF01490.18 EMC93302.1 - 9.7e-28 97.0 23.9 1.5e-27 96.4 23.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_47 PF01532.20 EMC93303.1 - 1.5e-116 390.1 0.0 1.7e-116 389.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HAUS6_N PF14661.6 EMC93304.1 - 9.2e-39 133.4 0.5 9.2e-39 133.4 0.5 1.7 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus TF_AP-2 PF03299.14 EMC93304.1 - 0.14 12.1 0.8 0.31 11.0 0.8 1.5 1 0 0 1 1 1 0 Transcription factor AP-2 Methyltransf_8 PF05148.15 EMC93305.1 - 1e-56 192.3 0.0 3.1e-55 187.4 0.0 2.8 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EMC93305.1 - 3.1e-05 24.5 0.0 0.00019 22.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC93305.1 - 0.00043 20.9 0.0 0.063 14.0 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EMC93305.1 - 0.028 14.4 0.3 0.21 11.6 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 EMC93305.1 - 0.078 12.8 0.0 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain HHV6-IE PF03753.13 EMC93305.1 - 0.16 9.4 0.1 0.24 8.8 0.1 1.2 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein BH4 PF02180.17 EMC93306.1 - 0.031 14.1 0.1 0.074 12.9 0.1 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 AAA PF00004.29 EMC93308.1 - 1.8e-36 125.5 0.0 2.8e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMC93308.1 - 4.7e-09 35.9 0.1 1.2e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EMC93308.1 - 3.8e-06 26.7 0.0 7.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMC93308.1 - 1.2e-05 25.8 0.2 0.00029 21.3 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EMC93308.1 - 4.3e-05 23.7 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMC93308.1 - 5.5e-05 23.2 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EMC93308.1 - 7.5e-05 22.9 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EMC93308.1 - 7.6e-05 22.7 0.1 0.00078 19.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMC93308.1 - 0.00011 22.4 0.2 0.0033 17.7 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMC93308.1 - 0.00025 21.6 0.0 0.00048 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMC93308.1 - 0.00057 19.5 0.1 0.033 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EMC93308.1 - 0.00076 18.9 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EMC93308.1 - 0.00082 18.8 0.0 1.3 8.4 0.0 2.7 2 1 1 3 3 3 2 Bacterial TniB protein RNA_helicase PF00910.22 EMC93308.1 - 0.001 19.4 0.0 0.0025 18.2 0.0 1.8 1 1 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 EMC93308.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 EMC93308.1 - 0.0038 17.2 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 EMC93308.1 - 0.0043 17.3 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMC93308.1 - 0.0064 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMC93308.1 - 0.0096 16.4 0.0 0.02 15.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EMC93308.1 - 0.012 15.5 0.1 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 EMC93308.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.6 EMC93308.1 - 0.029 14.2 0.1 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 EMC93308.1 - 0.039 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EMC93308.1 - 0.041 13.4 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EMC93308.1 - 0.045 13.0 0.1 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 EMC93308.1 - 0.046 13.8 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 EMC93308.1 - 0.052 13.4 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.13 EMC93308.1 - 0.061 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 EMC93308.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.6 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 EMC93308.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EMC93308.1 - 0.073 13.5 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EMC93308.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 EMC93308.1 - 0.088 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 EMC93308.1 - 0.091 12.1 0.0 0.58 9.5 0.0 2.0 1 1 1 2 2 2 0 KaiC Thymidylat_synt PF00303.19 EMC93309.1 - 1.4e-71 240.8 0.0 1.7e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Aldedh PF00171.22 EMC93310.1 - 5e-157 523.1 0.0 5.6e-157 522.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_6 PF12697.7 EMC93311.1 - 9.9e-11 42.7 0.0 2.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC93311.1 - 3.6e-09 36.7 0.0 0.00019 21.2 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC93311.1 - 4e-05 23.0 0.0 0.00057 19.2 0.1 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PBD PF00786.28 EMC93311.1 - 0.084 13.2 0.0 0.47 10.8 0.0 2.2 2 0 0 2 2 2 0 P21-Rho-binding domain FMN_dh PF01070.18 EMC93312.1 - 2.2e-110 369.0 0.0 2.5e-110 368.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EMC93312.1 - 0.00031 20.3 0.4 0.00051 19.5 0.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 EMC93312.1 - 0.00047 19.5 0.8 0.16 11.3 0.2 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EMC93312.1 - 0.00049 19.2 2.2 0.001 18.1 2.2 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMC93312.1 - 0.0029 16.8 0.1 0.0047 16.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase MRP-L47 PF06984.13 EMC93313.1 - 2e-18 66.3 0.1 2.9e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.18 EMC93315.1 - 3.1e-178 592.8 0.0 3.6e-178 592.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Cellulase PF00150.18 EMC93316.1 - 4.7e-16 59.1 0.0 6.4e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Adeno_E3_CR2 PF02439.15 EMC93318.1 - 0.1 12.4 0.3 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Fungal_trans PF04082.18 EMC93320.1 - 8e-64 215.2 0.5 1.3e-63 214.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EMC93320.1 - 0.0043 17.4 14.3 0.011 16.1 3.8 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC93320.1 - 0.064 13.7 10.8 0.43 11.1 3.1 3.0 2 0 0 2 2 2 0 Zinc-finger double domain HD_3 PF13023.6 EMC93322.1 - 7.1e-51 172.4 0.1 1e-50 171.9 0.1 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EMC93322.1 - 2.1e-12 47.2 0.0 2.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EMC93322.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 HD domain U-box PF04564.15 EMC93323.1 - 5.3e-20 71.4 0.1 1.3e-19 70.2 0.1 1.7 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 EMC93323.1 - 1.7e-08 34.0 5.7 0.00023 20.9 0.3 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC93323.1 - 3.1e-07 30.0 5.4 0.00039 20.3 0.3 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC93323.1 - 4.8e-06 26.7 0.9 0.083 13.1 0.1 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EMC93323.1 - 1e-05 25.9 0.9 0.0035 17.8 0.0 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMC93323.1 - 1.8e-05 24.3 0.4 0.00022 20.8 0.1 2.8 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EMC93323.1 - 2e-05 25.1 1.1 0.00081 20.0 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat zf-Nse PF11789.8 EMC93323.1 - 0.00041 20.1 0.1 0.0013 18.5 0.1 1.8 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_7 PF13176.6 EMC93323.1 - 0.00064 19.6 0.5 0.026 14.5 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMC93323.1 - 0.0013 19.0 7.2 0.17 12.2 0.1 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMC93323.1 - 0.0015 19.2 4.7 0.18 12.7 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 EMC93323.1 - 0.0021 18.8 1.8 0.0048 17.6 1.8 1.6 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain zf-NOSIP PF15906.5 EMC93323.1 - 0.016 15.3 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein RD3 PF14473.6 EMC93323.1 - 0.019 14.8 0.5 0.047 13.5 0.5 1.6 1 1 0 1 1 1 0 RD3 protein TPR_10 PF13374.6 EMC93323.1 - 0.024 14.5 0.1 0.024 14.5 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMC93323.1 - 0.03 14.5 0.8 2.3 8.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 EMC93323.1 - 0.058 13.1 0.4 0.058 13.1 0.4 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 EMC93323.1 - 0.082 13.3 5.4 0.14 12.6 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat PTS_IIA PF02255.16 EMC93323.1 - 2.4 8.3 7.9 0.93 9.6 0.5 2.8 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit SRPRB PF09439.10 EMC93324.1 - 3.5e-34 117.8 0.0 1.9e-33 115.4 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EMC93324.1 - 3.3e-07 29.9 0.0 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMC93324.1 - 4e-05 23.7 0.0 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EMC93324.1 - 0.00022 21.7 0.3 0.00055 20.4 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMC93324.1 - 0.00037 20.8 0.1 0.00076 19.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EMC93324.1 - 0.00041 19.9 0.0 0.0012 18.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 EMC93324.1 - 0.00079 18.9 0.0 0.0019 17.7 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein Gtr1_RagA PF04670.12 EMC93324.1 - 0.00082 18.8 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EMC93324.1 - 0.0025 18.0 0.0 0.0073 16.5 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EMC93324.1 - 0.0029 18.1 0.2 0.0061 17.1 0.2 1.6 1 1 0 1 1 1 1 ABC transporter cobW PF02492.19 EMC93324.1 - 0.0038 16.8 0.2 0.52 9.9 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EMC93324.1 - 0.004 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ras PF00071.22 EMC93324.1 - 0.0089 15.6 0.0 0.056 13.0 0.0 2.0 1 1 0 1 1 1 1 Ras family ATP_bind_1 PF03029.17 EMC93324.1 - 0.0094 15.8 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EMC93324.1 - 0.011 15.6 0.2 0.038 13.9 0.1 1.9 2 1 0 2 2 2 0 RsgA GTPase Septin PF00735.18 EMC93324.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 EMC93324.1 - 0.015 15.8 0.1 0.035 14.6 0.1 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMC93324.1 - 0.035 14.0 0.0 0.077 12.9 0.0 1.6 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.6 EMC93324.1 - 0.058 13.1 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EMC93324.1 - 0.06 13.8 0.5 0.19 12.1 0.5 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMC93324.1 - 0.07 13.1 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EMC93324.1 - 0.095 12.9 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EMC93324.1 - 0.098 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 EMC93324.1 - 0.098 12.7 0.6 0.24 11.4 0.3 1.6 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EMC93324.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EMC93324.1 - 0.17 11.6 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation adh_short PF00106.25 EMC93325.1 - 1.1e-22 80.4 0.2 3.6e-22 78.8 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93325.1 - 8.2e-12 45.2 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC93325.1 - 6.2e-05 23.0 0.1 9.2e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC93325.1 - 0.00038 20.0 0.0 0.00054 19.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC93325.1 - 0.025 13.7 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ATP-synt_DE_N PF02823.16 EMC93325.1 - 0.029 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain MTS_N PF08468.11 EMC93325.1 - 0.05 13.7 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Glyco_tran_WecB PF03808.13 EMC93325.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family NDT80_PhoG PF05224.12 EMC93326.1 - 7.7e-37 127.3 0.0 1.5e-36 126.4 0.0 1.5 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family NPM1-C PF16276.5 EMC93326.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain SH3_1 PF00018.28 EMC93327.1 - 1.3e-09 37.5 1.8 1.9e-09 37.0 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EMC93327.1 - 4.5e-08 32.8 0.2 1.8e-07 30.9 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EMC93327.1 - 3.6e-05 23.3 1.3 6.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain RPAP2_Rtr1 PF04181.13 EMC93328.1 - 1e-14 54.6 1.1 1.2e-13 51.1 0.8 2.6 2 1 0 2 2 2 1 Rtr1/RPAP2 family Pterin_bind PF00809.22 EMC93329.1 - 1.6e-78 263.8 0.3 7.4e-78 261.6 0.1 2.0 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.20 EMC93329.1 - 1.7e-36 125.1 0.0 3.6e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 EMC93330.1 - 9.4e-55 186.3 1.3 1.4e-54 185.8 1.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EMC93330.1 - 2e-10 40.2 4.1 1.9e-09 37.0 4.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EMC93330.1 - 6.6e-07 28.7 2.0 1.3e-06 27.7 2.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EMC93330.1 - 0.0032 16.7 2.6 0.0037 16.4 1.6 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EMC93330.1 - 0.079 12.1 0.3 0.14 11.3 0.3 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Syntaxin-18_N PF10496.9 EMC93331.1 - 2.8e-09 37.1 0.5 3.3e-08 33.6 0.1 3.0 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EMC93331.1 - 0.013 15.4 0.8 0.079 13.0 0.0 2.2 2 0 0 2 2 2 0 SNARE domain RNR_inhib PF08591.10 EMC93331.1 - 0.073 14.4 0.4 0.2 13.0 0.4 1.8 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor DprA_WH PF17782.1 EMC93331.1 - 0.2 11.8 4.0 0.24 11.6 0.2 2.9 2 1 1 3 3 3 0 DprA winged helix domain FUSC PF04632.12 EMC93331.1 - 0.52 8.8 6.1 1.7 7.1 0.1 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 EMC93331.1 - 1.8 8.7 8.9 0.83 9.8 2.4 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1542 PF07564.11 EMC93331.1 - 3.5 7.8 11.1 2.1 8.5 0.1 3.8 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1542) DUF3450 PF11932.8 EMC93331.1 - 8.4 5.6 11.9 5.1 6.3 3.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Aminotran_1_2 PF00155.21 EMC93332.1 - 1.6e-80 271.0 0.0 1.9e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PI3K_P85_iSH2 PF16454.5 EMC93333.1 - 0.016 14.8 0.0 0.086 12.4 0.0 1.9 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BLOC1_2 PF10046.9 EMC93333.1 - 0.05 13.9 0.3 0.12 12.7 0.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 EMC93333.1 - 0.083 12.5 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Intermediate filament protein Tropomyosin_1 PF12718.7 EMC93333.1 - 0.12 12.5 0.1 19 5.4 0.0 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF4254 PF14063.6 EMC93333.1 - 0.13 12.1 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) DUF4618 PF15397.6 EMC93333.1 - 0.13 11.7 0.2 0.23 10.8 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Lzipper-MIP1 PF14389.6 EMC93333.1 - 0.15 12.4 0.0 0.61 10.4 0.0 1.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Tropomyosin PF00261.20 EMC93333.1 - 0.16 11.3 0.0 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Tropomyosin Csm1_N PF18504.1 EMC93333.1 - 0.22 11.9 0.6 0.83 10.0 0.1 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain TolA_bind_tri PF16331.5 EMC93333.1 - 0.24 11.5 1.7 0.45 10.6 0.1 2.2 3 0 0 3 3 3 0 TolA binding protein trimerisation TIM PF00121.18 EMC93334.1 - 1.3e-51 175.3 0.0 1.5e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MTHFR PF02219.17 EMC93335.1 - 1.1e-110 369.5 0.0 1.4e-110 369.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PigN PF04987.14 EMC93337.1 - 6.3e-162 539.6 18.2 7.7e-162 539.3 18.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EMC93337.1 - 2.1e-09 37.4 2.9 5e-08 32.9 2.9 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMC93337.1 - 4.8e-07 29.5 0.3 2.2e-06 27.3 0.1 2.0 1 1 1 2 2 2 1 Sulfatase HET PF06985.11 EMC93338.1 - 1.9e-09 38.0 2.6 1.4e-05 25.5 0.1 2.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) ATP-synt_F PF01990.17 EMC93339.1 - 1.6e-31 108.5 0.1 1.8e-31 108.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 EMC93340.1 - 4.4e-27 95.1 0.3 4.9e-27 95.0 0.3 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EMC93340.1 - 0.00077 19.8 0.0 0.0014 19.0 0.0 1.5 1 1 0 1 1 1 1 ML-like domain Big_9 PF17963.1 EMC93340.1 - 0.094 13.5 0.0 0.23 12.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial Ig domain NPCBM_assoc PF10633.9 EMC93340.1 - 0.12 12.7 0.1 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Coatomer_WDAD PF04053.14 EMC93341.1 - 4.4e-167 556.7 0.0 1.1e-166 555.3 0.0 1.7 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EMC93341.1 - 4.5e-38 128.6 7.8 6.3e-06 26.8 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC93341.1 - 8.9e-08 32.3 0.0 3.5 8.0 0.0 6.4 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC93341.1 - 0.00021 20.1 1.9 0.25 9.9 0.1 3.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Pox_Rif PF03340.13 EMC93341.1 - 0.013 14.0 0.0 0.1 11.0 0.0 2.0 2 0 0 2 2 2 0 Poxvirus rifampicin resistance protein BBS2_Mid PF14783.6 EMC93341.1 - 0.02 14.9 0.0 8.3 6.5 0.0 3.5 1 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 EMC93341.1 - 0.032 14.1 0.0 25 4.7 0.0 3.7 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Methyltransf_2 PF00891.18 EMC93342.1 - 3.2e-27 95.2 0.0 5.5e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Get5_C PF18514.1 EMC93342.1 - 0.066 12.9 0.1 0.32 10.7 0.1 2.1 2 0 0 2 2 2 0 Get5 C-terminal domain Methyltransf_25 PF13649.6 EMC93342.1 - 0.079 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 EMC93344.1 - 3.8e-38 130.9 0.2 5.1e-38 130.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93344.1 - 2.9e-36 125.2 0.1 4.1e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC93344.1 - 2e-16 60.4 0.2 2.9e-16 59.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMC93344.1 - 0.0035 16.5 0.0 0.0044 16.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMC93344.1 - 0.0085 15.6 0.1 0.013 14.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Chlorophyllase PF07224.11 EMC93344.1 - 0.015 14.3 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase PhyH PF05721.13 EMC93346.1 - 1.4e-28 100.6 0.1 1.7e-28 100.3 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EMC93346.1 - 6.9e-05 23.2 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 EMC93346.1 - 0.083 13.8 0.1 0.22 12.5 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily HD PF01966.22 EMC93347.1 - 1.4e-08 35.0 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 EMC93347.1 - 0.00022 21.0 0.1 0.00035 20.3 0.1 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EMC93347.1 - 0.0077 15.7 0.1 0.03 13.8 0.1 1.8 1 1 0 1 1 1 1 HDOD domain MIOX PF05153.15 EMC93347.1 - 0.042 13.4 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase Zn_clus PF00172.18 EMC93348.1 - 1.7e-09 37.6 8.5 2.9e-09 36.9 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC93348.1 - 1.5e-05 24.2 0.1 2.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NOT2_3_5 PF04153.18 EMC93349.1 - 5.2e-22 78.3 0.0 5.2e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family CUE PF02845.16 EMC93350.1 - 9.3e-09 34.8 0.0 1.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 EMC93350.1 - 0.36 10.5 5.3 0.26 11.0 3.4 1.7 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) ATP_synt_H PF05493.13 EMC93351.1 - 1.9e-21 76.2 7.0 2.3e-21 76.0 7.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Yip1 PF04893.17 EMC93351.1 - 0.2 11.4 7.9 0.25 11.1 7.9 1.1 1 0 0 1 1 1 0 Yip1 domain Arv1 PF04161.13 EMC93352.1 - 9.7e-74 248.1 0.0 1.2e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family ACBP PF00887.19 EMC93353.1 - 7.9e-20 70.9 2.3 9e-20 70.7 2.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein SMC_N PF02463.19 EMC93354.1 - 8.3e-65 218.3 0.0 1.8e-64 217.2 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Ribosomal_S17e PF00833.18 EMC93354.1 - 8.5e-53 177.4 0.3 8.5e-53 177.4 0.3 3.0 2 0 0 2 2 2 1 Ribosomal S17 SMC_hinge PF06470.13 EMC93354.1 - 2.7e-19 69.6 0.9 1.5e-18 67.2 0.2 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EMC93354.1 - 6.5e-14 52.9 8.8 6.5e-14 52.9 8.8 6.4 2 2 1 5 5 5 1 AAA domain AAA_21 PF13304.6 EMC93354.1 - 2.8e-11 43.8 1.8 8.5e-05 22.5 0.2 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system GAS PF13851.6 EMC93354.1 - 0.00014 21.3 5.1 0.00014 21.3 5.1 7.4 3 2 3 7 7 7 2 Growth-arrest specific micro-tubule binding AAA_29 PF13555.6 EMC93354.1 - 0.00076 19.2 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 EMC93354.1 - 0.0057 16.8 10.1 0.0057 16.8 10.1 7.8 3 2 3 7 7 7 1 Tropomyosin like ABC_tran PF00005.27 EMC93354.1 - 0.29 11.6 19.7 1.5 9.3 0.1 5.3 4 1 0 4 4 4 0 ABC transporter NAT PF04768.13 EMC93355.1 - 3.6e-52 176.5 0.0 9.5e-52 175.1 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DotU PF09850.9 EMC93355.1 - 0.019 14.7 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Type VI secretion system protein DotU AA_kinase PF00696.28 EMC93355.1 - 0.042 13.4 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 Amino acid kinase family DUF3958 PF13125.6 EMC93355.1 - 0.13 12.5 0.1 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) LacAB_rpiB PF02502.18 EMC93356.1 - 9.3e-44 148.8 0.1 1.1e-43 148.6 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.8 EMC93356.1 - 0.029 14.5 0.3 0.072 13.2 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF2620 Gly_rich_SFCGS PF14272.6 EMC93356.1 - 0.057 13.4 0.8 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Glycine-rich SFCGS GST_N PF02798.20 EMC93357.1 - 4.1e-10 39.9 0.0 8.6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMC93357.1 - 1.5e-06 28.5 0.0 2.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMC93357.1 - 1.2e-05 25.4 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMC93357.1 - 0.00011 22.3 0.1 0.00019 21.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMC93357.1 - 0.0012 18.8 0.6 0.0026 17.8 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMC93357.1 - 0.0015 18.8 0.0 0.005 17.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Fe-ADH PF00465.19 EMC93358.1 - 3.5e-51 174.1 0.0 6.2e-51 173.3 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMC93358.1 - 1.1e-05 25.3 0.2 0.00048 19.9 0.0 2.5 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase Gpr1_Fun34_YaaH PF01184.19 EMC93359.1 - 9.3e-31 107.0 21.5 1.2e-30 106.7 21.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Zn_Tnp_IS91 PF14319.6 EMC93360.1 - 0.014 15.5 2.2 0.014 15.5 2.2 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain p450 PF00067.22 EMC93362.1 - 3.1e-45 154.8 0.0 3.9e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SH3BGR PF04908.15 EMC93364.1 - 6.8e-07 29.4 0.0 8.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 EMC93364.1 - 0.00025 21.2 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Aldo_ket_red PF00248.21 EMC93365.1 - 5.2e-47 160.5 0.0 5.9e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.21 EMC93366.1 - 1.4e-41 141.9 0.5 1.4e-41 141.9 0.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Tim17 PF02466.19 EMC93367.1 - 1.2e-12 48.2 1.1 2.2e-12 47.3 1.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tox-HDC PF15656.6 EMC93367.1 - 0.095 12.9 0.0 0.17 12.1 0.0 1.5 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature Pro-kuma_activ PF09286.11 EMC93369.1 - 1.4e-47 161.5 0.3 6.1e-46 156.2 0.2 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMC93369.1 - 0.0042 16.4 1.8 0.0068 15.7 1.8 1.4 1 0 0 1 1 1 1 Subtilase family Sigma70_r4 PF04545.16 EMC93369.1 - 0.1 12.1 0.2 4 7.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 CBFB_NFYA PF02045.15 EMC93373.1 - 9.5e-29 99.8 5.0 9.5e-29 99.8 5.0 1.6 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 EMC93373.1 - 0.03 13.4 0.1 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 Hus1-like protein Ribosomal_L37 PF08561.10 EMC93374.1 - 4.8e-25 88.4 5.4 2.9e-24 85.9 1.6 2.7 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L37 WD40 PF00400.32 EMC93376.1 - 2.3e-14 53.5 1.5 0.016 16.0 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC93376.1 - 0.0023 18.2 0.1 3.5 8.0 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Abhydro_lipase PF04083.16 EMC93378.1 - 2.4e-18 65.5 0.0 6.3e-18 64.1 0.0 1.8 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EMC93378.1 - 1.8e-08 34.4 0.0 4.2e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC93378.1 - 8.7e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 EMC93378.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) AAA PF00004.29 EMC93380.1 - 6.4e-46 156.0 0.0 1.3e-42 145.3 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMC93380.1 - 3.5e-05 24.3 0.2 0.025 15.0 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain AAA_lid_3 PF17862.1 EMC93380.1 - 6.4e-05 22.7 5.7 0.01 15.6 0.1 3.0 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 EMC93380.1 - 0.00015 21.5 0.0 0.00053 19.8 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EMC93380.1 - 0.0006 19.0 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 EMC93380.1 - 0.0022 18.1 0.0 0.0092 16.1 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMC93380.1 - 0.0029 17.9 0.0 0.044 14.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EMC93380.1 - 0.004 17.5 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.13 EMC93380.1 - 0.0056 15.9 0.1 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EMC93380.1 - 0.0069 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EMC93380.1 - 0.011 15.3 0.0 0.051 13.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMC93380.1 - 0.024 14.2 0.0 0.06 12.9 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EMC93380.1 - 0.025 14.0 0.5 0.057 12.8 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMC93380.1 - 0.025 14.6 0.0 0.12 12.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EMC93380.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 EMC93380.1 - 0.041 14.4 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EMC93380.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EMC93380.1 - 0.077 12.7 0.0 2.3 7.9 0.0 3.0 4 0 0 4 4 3 0 Sigma-54 interaction domain PhoH PF02562.16 EMC93380.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 EMC93380.1 - 0.12 12.4 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMC93380.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMC93380.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 EMC93381.1 - 1.1e-92 311.2 0.0 1.3e-92 311.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-3_zeta PF05091.12 EMC93382.1 - 4.5e-200 666.1 0.0 5.3e-200 665.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Abhydrolase_3 PF07859.13 EMC93384.1 - 2.6e-41 141.8 0.0 3.7e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EMC93384.1 - 0.0048 17.0 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain COesterase PF00135.28 EMC93384.1 - 0.037 12.9 0.1 0.056 12.3 0.1 1.3 1 1 0 1 1 1 0 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC93385.1 - 3.7e-57 193.6 0.1 4.8e-57 193.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMC93385.1 - 3.2e-12 46.0 0.0 4e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EMC93385.1 - 0.0088 15.5 0.8 0.52 9.7 0.4 2.8 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EMC93385.1 - 0.036 14.7 0.2 0.049 14.2 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0004 PF00919.20 EMC93385.1 - 0.16 12.1 0.0 1.1 9.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 adh_short_C2 PF13561.6 EMC93386.1 - 8.1e-52 176.1 0.1 1e-51 175.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC93386.1 - 5.4e-34 117.4 0.0 7.1e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC93386.1 - 1e-08 35.3 0.0 1.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC93386.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 EMC93388.1 - 2.9e-24 85.8 0.0 4.2e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC93388.1 - 6.9e-10 38.6 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.28 EMC93389.1 - 8.6e-37 124.5 7.4 2.4e-13 49.4 0.4 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EMC93389.1 - 7.6e-35 118.5 8.8 3.1e-13 49.4 0.3 4.2 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 EMC93389.1 - 4.8e-34 116.0 0.0 8e-34 115.3 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 EMC93389.1 - 2e-18 65.8 0.0 1.2e-07 31.3 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_10 PF17902.1 EMC93389.1 - 0.00035 20.6 0.1 3.4 7.8 0.0 3.5 3 0 0 3 3 3 2 SH3 domain SH3_3 PF08239.11 EMC93389.1 - 0.0084 16.4 3.2 0.66 10.3 0.4 3.2 3 0 0 3 3 3 1 Bacterial SH3 domain SAM_4 PF18017.1 EMC93389.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PKS_DE PF18369.1 EMC93391.1 - 0.07 13.7 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain SUI1 PF01253.22 EMC93392.1 - 4.4e-26 91.2 0.0 7.8e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pkinase PF00069.25 EMC93393.1 - 2e-46 158.5 0.0 3.6e-46 157.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC93393.1 - 3.3e-19 69.2 0.0 6.3e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EMC93393.1 - 0.0017 17.9 0.2 0.0068 16.0 0.0 1.9 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 EMC93393.1 - 0.0025 17.8 0.1 0.36 10.7 0.3 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EMC93393.1 - 0.0048 16.3 0.2 0.0078 15.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMC93393.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Draxin PF15550.6 EMC93394.1 - 0.024 14.5 0.2 0.03 14.2 0.2 1.1 1 0 0 1 1 1 0 Draxin Cytochrom_C_asm PF01578.20 EMC93394.1 - 0.033 14.0 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein Stevor PF17410.2 EMC93394.1 - 0.29 10.6 0.2 0.4 10.2 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Shisa PF13908.6 EMC93394.1 - 1 9.6 3.1 2.1 8.6 3.1 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Mito_carr PF00153.27 EMC93395.1 - 7e-65 215.0 0.5 4.6e-20 71.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMC93395.1 - 0.25 10.4 1.9 1.6 7.8 0.1 3.0 4 0 0 4 4 4 0 Gammaproteobacterial serine protease TauD PF02668.16 EMC93396.1 - 1.6e-44 152.8 2.4 7.9e-44 150.5 2.4 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CrgA PF06781.12 EMC93397.1 - 0.81 9.8 2.3 2.2 8.4 2.3 1.7 1 0 0 1 1 1 0 Cell division protein CrgA CorA PF01544.18 EMC93399.1 - 0.013 14.8 0.1 0.013 14.8 0.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein COesterase PF00135.28 EMC93400.1 - 4.1e-54 184.3 0.0 6.4e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC93400.1 - 1.3e-09 38.2 0.1 6.5e-09 36.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC93400.1 - 0.056 14.0 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EMC93400.1 - 0.13 11.0 0.0 1.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase DUF1772 PF08592.11 EMC93401.1 - 2e-21 76.8 4.3 2.4e-21 76.5 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) WD40 PF00400.32 EMC93402.1 - 1.3e-06 29.1 11.2 0.0037 18.1 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Kri1 PF05178.12 EMC93402.1 - 5.1 7.7 7.4 7.1 7.2 0.4 2.5 2 0 0 2 2 2 0 KRI1-like family ATP-synt_E PF05680.12 EMC93403.1 - 5.3e-19 68.4 1.1 6.9e-19 68.0 1.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF2229 PF09989.9 EMC93403.1 - 0.078 12.6 0.0 0.093 12.4 0.0 1.0 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF3818 PF12825.7 EMC93404.1 - 1.1e-124 415.9 0.0 1.6e-124 415.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EMC93404.1 - 6.7e-39 132.9 1.9 1.2e-38 132.0 1.9 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EMC93404.1 - 4e-11 42.9 1.9 6.3e-10 39.0 0.4 3.1 2 1 0 2 2 2 1 PX domain Mito_carr PF00153.27 EMC93405.1 - 3e-62 206.6 0.1 1.5e-22 79.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMC93405.1 - 0.00074 18.8 0.7 0.73 8.9 0.0 3.0 3 0 0 3 3 3 2 Gammaproteobacterial serine protease Antimicrobial_6 PF08036.11 EMC93405.1 - 0.04 14.0 0.4 2.8 8.1 0.2 2.4 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide Cgr1 PF03879.14 EMC93406.1 - 1e-31 109.5 32.3 1.1e-31 109.3 32.3 1.0 1 0 0 1 1 1 1 Cgr1 family zf-SAP30 PF13866.6 EMC93406.1 - 4 7.6 11.5 0.44 10.7 6.1 2.1 1 1 1 2 2 2 0 SAP30 zinc-finger Pannexin_like PF12534.8 EMC93406.1 - 4.8 6.2 6.7 5.3 6.0 6.7 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pex26 PF07163.12 EMC93406.1 - 9.2 5.5 10.4 11 5.2 10.4 1.1 1 0 0 1 1 1 0 Pex26 protein DUF1036 PF06282.11 EMC93407.1 - 0.071 13.6 0.2 0.17 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1036) adh_short PF00106.25 EMC93410.1 - 2.7e-39 134.6 0.6 4.5e-39 133.9 0.6 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93410.1 - 7.4e-37 127.1 0.1 1.2e-35 123.2 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC93410.1 - 4.1e-09 36.6 1.3 3.1e-08 33.7 0.1 2.2 2 0 0 2 2 2 1 KR domain HATPase_c PF02518.26 EMC93410.1 - 0.015 15.8 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox PF00070.27 EMC93410.1 - 0.046 14.3 1.1 0.13 12.8 0.3 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMC93410.1 - 0.14 12.0 0.3 0.27 11.1 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain A_deaminase PF00962.22 EMC93411.1 - 1.3e-122 409.3 0.2 1.9e-122 408.7 0.2 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Mt_ATP-synt_B PF05405.14 EMC93412.1 - 1.8e-50 170.7 5.1 2.2e-50 170.4 5.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Dak2 PF02734.17 EMC93412.1 - 0.13 12.1 1.1 0.41 10.5 1.1 1.9 1 1 0 1 1 1 0 DAK2 domain CBF PF03914.17 EMC93413.1 - 3.1e-36 125.0 0.6 1e-35 123.3 0.1 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Alpha-amylase PF00128.24 EMC93413.1 - 0.046 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Luteo_PO PF04662.13 EMC93413.1 - 0.067 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Luteovirus P0 protein Rad17 PF03215.15 EMC93418.1 - 6.6e-28 97.9 0.0 1.1e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EMC93418.1 - 0.011 15.5 0.3 0.021 14.6 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMC93418.1 - 0.012 16.1 0.0 0.032 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EMC93418.1 - 0.017 15.2 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EMC93418.1 - 0.017 15.5 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EMC93418.1 - 0.024 14.9 0.3 0.045 14.0 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EMC93418.1 - 0.031 14.7 0.0 0.058 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMC93418.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain 2OG-FeII_Oxy_2 PF13532.6 EMC93419.1 - 8.9e-27 94.6 0.0 1.2e-26 94.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ArfGap PF01412.18 EMC93421.1 - 0.021 14.9 1.3 0.027 14.5 1.3 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf NDUFB10 PF10249.9 EMC93422.1 - 0.00073 20.0 0.1 0.0008 19.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 EMC93422.1 - 0.055 14.2 0.0 0.094 13.4 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase FAM216B PF15107.6 EMC93422.1 - 0.11 12.4 0.5 0.14 12.0 0.5 1.5 1 1 0 1 1 1 0 FAM216B protein family BRO1 PF03097.18 EMC93423.1 - 8.9e-11 41.2 0.0 1.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Acetyltransf_1 PF00583.25 EMC93423.1 - 0.16 12.2 0.0 0.99 9.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family AA_permease_2 PF13520.6 EMC93424.1 - 5.7e-61 206.6 52.5 7e-61 206.3 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC93424.1 - 2.6e-12 46.1 38.4 3.8e-12 45.6 38.4 1.3 1 0 0 1 1 1 1 Amino acid permease Phage_holin_2_2 PF10746.9 EMC93424.1 - 0.34 10.6 4.2 0.24 11.1 0.1 2.7 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II ADH_N_2 PF16884.5 EMC93425.1 - 1.6e-25 89.1 0.0 2.5e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EMC93425.1 - 6.6e-20 71.4 0.1 9.9e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC93425.1 - 1.8e-05 25.8 0.0 3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.16 EMC93425.1 - 0.11 11.9 0.2 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DAO PF01266.24 EMC93428.1 - 2.5e-30 106.3 0.8 3.1e-30 106.0 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC93428.1 - 5.5e-06 26.5 1.5 8.2e-06 26.0 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMC93428.1 - 0.0032 16.8 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC93428.1 - 0.03 13.5 0.0 0.092 12.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC93428.1 - 0.034 13.2 0.3 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EMC93428.1 - 0.037 14.0 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EMC93428.1 - 0.043 13.1 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 EMC93428.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Sugar_tr PF00083.24 EMC93429.1 - 1.6e-70 238.2 27.9 1.9e-70 238.0 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC93429.1 - 8.1e-18 64.4 45.1 1.5e-12 47.1 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 EMC93430.1 - 4.8e-52 175.9 0.0 6.2e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMC93430.1 - 7.8e-16 58.0 0.0 9.1e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMC93430.1 - 5.6e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Asp_Glu_race PF01177.22 EMC93431.1 - 0.08 12.8 0.0 2.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase Aldolase_II PF00596.21 EMC93432.1 - 2.4e-48 164.6 0.0 3.2e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1338 PF07063.13 EMC93433.1 - 4.9e-109 364.5 0.1 5.7e-109 364.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Glyoxalase PF00903.25 EMC93433.1 - 0.056 13.7 0.0 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 EMC93434.1 - 8e-32 110.3 0.0 1.3e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93434.1 - 7.8e-08 32.3 8.1 1.6e-07 31.3 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF326 PF03860.16 EMC93434.1 - 0.057 13.4 0.5 0.2 11.7 0.5 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) Pkinase PF00069.25 EMC93435.1 - 1.6e-60 204.7 0.0 4e-60 203.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC93435.1 - 2e-34 119.1 0.0 5.6e-34 117.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EMC93435.1 - 8.7e-10 38.8 0.5 8.8e-09 35.6 0.1 2.8 3 0 0 3 3 3 1 FHA domain Kinase-like PF14531.6 EMC93435.1 - 0.00034 20.0 0.0 0.0025 17.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 EMC93435.1 - 0.00078 19.7 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EMC93435.1 - 0.043 13.2 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMC93435.1 - 0.052 12.3 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FMO-like PF00743.19 EMC93437.1 - 6.2e-13 48.0 0.8 5.9e-11 41.5 0.0 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMC93437.1 - 1.5e-11 44.1 0.0 1.8e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC93437.1 - 9e-11 41.9 0.2 4.3e-07 30.1 0.1 3.7 4 0 0 4 4 4 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMC93437.1 - 1.4e-05 24.5 0.0 7e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC93437.1 - 3e-05 24.0 0.1 0.14 12.1 0.0 3.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EMC93437.1 - 3.8e-05 23.0 0.0 0.00035 19.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EMC93437.1 - 0.00021 21.8 1.9 0.063 13.9 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMC93437.1 - 0.00045 19.4 0.2 0.2 10.6 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 EMC93437.1 - 0.014 15.0 1.2 0.26 10.8 0.0 2.7 2 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMC93437.1 - 0.017 14.2 0.3 0.065 12.3 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 EMC93437.1 - 0.061 13.0 0.5 12 5.6 0.0 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EMC93437.1 - 0.19 10.9 0.4 3.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Thi4 family DUF3591 PF12157.8 EMC93438.1 - 2.7e-167 556.9 4.8 3.7e-167 556.5 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 EMC93438.1 - 0.0031 17.3 1.6 0.0087 15.9 1.6 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EMC93438.1 - 0.0051 16.8 0.7 0.0094 16.0 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Peptidase_S28 PF05577.12 EMC93440.1 - 1.3e-44 152.8 6.5 2.2e-43 148.7 6.5 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 GYF PF02213.16 EMC93440.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.7 3 0 0 3 3 3 0 GYF domain Sec10 PF07393.11 EMC93441.1 - 3.5e-203 677.0 0.0 4.6e-203 676.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Sugarporin_N PF11471.8 EMC93442.1 - 5.9e-05 22.9 9.6 0.059 13.3 0.1 4.0 4 1 0 4 4 4 2 Maltoporin periplasmic N-terminal extension DUF465 PF04325.13 EMC93442.1 - 0.052 13.6 2.5 0.92 9.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF465) GAGA_bind PF06217.12 EMC93442.1 - 1.9 8.7 7.5 1.1 9.5 5.3 1.6 1 1 1 2 2 2 0 GAGA binding protein-like family DUF4770 PF15994.5 EMC93442.1 - 6.4 7.0 8.4 5.1 7.3 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) adh_short_C2 PF13561.6 EMC93443.1 - 7e-30 104.3 0.0 2.7e-29 102.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC93443.1 - 5.5e-24 84.7 0.0 9.2e-24 84.0 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC93443.1 - 2e-05 24.6 0.0 7.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 KR domain DUF4440 PF14534.6 EMC93444.1 - 0.021 15.2 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EMC93444.1 - 0.026 15.1 0.0 0.045 14.4 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain CAP160 PF07918.11 EMC93444.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 CAP160 repeat PIR PF00399.19 EMC93445.1 - 0.00025 20.5 5.3 0.0019 17.7 5.3 2.7 1 0 0 1 1 1 1 Yeast PIR protein repeat Sugar_tr PF00083.24 EMC93447.1 - 6.9e-27 94.4 20.1 6e-16 58.4 6.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter HSCB_C PF07743.13 EMC93449.1 - 5.7e-21 74.8 9.9 6.6e-21 74.6 4.4 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EMC93449.1 - 4.6e-08 33.1 0.7 4.6e-08 33.1 0.7 1.8 2 0 0 2 2 2 1 DnaJ domain dCMP_cyt_deam_1 PF00383.23 EMC93450.1 - 4.5e-15 55.3 1.5 5.7e-15 55.0 1.5 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EMC93450.1 - 1.9e-12 47.5 1.4 1.2e-09 38.5 0.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EMC93450.1 - 0.009 15.6 3.2 0.74 9.4 0.3 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DUF3169 PF11368.8 EMC93451.1 - 0.19 11.2 0.1 0.67 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) UL17 PF17640.2 EMC93451.1 - 0.47 10.5 3.2 1.9 8.5 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized UL17 RskA PF10099.9 EMC93451.1 - 5.4 7.3 9.7 0.22 11.8 0.3 2.5 3 0 0 3 3 3 0 Anti-sigma-K factor rskA THF_DHG_CYH PF00763.23 EMC93452.1 - 4.7e-21 75.2 0.0 7e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EMC93452.1 - 4.6e-13 48.8 0.0 6.4e-09 35.3 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MMS19_N PF14500.6 EMC93453.1 - 5.6e-89 298.2 4.6 1.4e-86 290.3 0.1 4.1 3 1 2 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EMC93453.1 - 5e-84 282.9 2.4 3.1e-83 280.3 0.2 2.9 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Tti2 PF10521.9 EMC93453.1 - 0.0029 17.2 0.7 0.3 10.6 0.0 3.8 4 0 0 4 4 4 1 Tti2 family Sec3_C_2 PF15278.6 EMC93453.1 - 0.063 13.6 0.4 2.2 8.7 0.1 2.7 2 0 0 2 2 2 0 Sec3 exocyst complex subunit HEAT_2 PF13646.6 EMC93453.1 - 0.34 11.3 12.3 0.096 13.1 0.9 5.2 5 1 0 5 5 5 0 HEAT repeats TAF6_C PF07571.13 EMC93453.1 - 0.36 11.2 3.1 3.2 8.1 0.0 3.6 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain IFRD PF05004.13 EMC93453.1 - 1.3 8.1 8.0 0.85 8.7 0.2 3.6 3 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 EMC93453.1 - 7.4 7.2 10.1 2.9 8.5 2.4 4.6 3 1 1 4 4 4 0 HEAT-like repeat SH3_9 PF14604.6 EMC93454.1 - 1.1e-29 102.0 2.1 1e-13 50.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EMC93454.1 - 1.9e-29 101.0 3.5 4.5e-14 51.8 0.2 2.4 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 EMC93454.1 - 3.8e-15 55.8 0.0 6.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 EMC93454.1 - 9.3e-15 54.1 0.0 1.3e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain F-box PF00646.33 EMC93455.1 - 0.00035 20.3 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMC93455.1 - 0.0028 17.5 0.2 0.006 16.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like DND1_DSRM PF14709.7 EMC93458.1 - 0.011 15.9 0.1 0.069 13.4 0.1 1.9 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 EMC93458.1 - 0.061 14.0 0.0 0.19 12.5 0.0 1.9 1 1 0 1 1 1 0 Double-stranded RNA binding motif PmbA_TldD PF01523.16 EMC93458.1 - 0.19 11.5 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Xan_ur_permease PF00860.20 EMC93459.1 - 1.7e-67 227.8 32.4 3e-66 223.7 32.4 2.0 1 1 0 1 1 1 1 Permease family Dak1 PF02733.17 EMC93460.1 - 1.3e-89 300.2 0.0 1.5e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain Methyltransf_16 PF10294.9 EMC93461.1 - 4.1e-13 49.4 0.0 3.7e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Pribosyltran PF00156.27 EMC93462.1 - 6.7e-16 58.2 0.0 9.8e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF2811 PF10929.8 EMC93462.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) AMP-binding PF00501.28 EMC93463.1 - 3.7e-89 299.3 0.0 5.4e-89 298.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC93463.1 - 1e-05 26.4 0.1 3.1e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECM11 PF15463.6 EMC93464.1 - 4e-35 121.3 0.2 9.2e-35 120.1 0.2 1.7 1 0 0 1 1 1 1 Extracellular mutant protein 11 F-box-like PF12937.7 EMC93465.1 - 7.4e-06 25.8 2.6 9.9e-06 25.4 0.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EMC93465.1 - 0.0081 16.0 0.2 0.018 14.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain rhaM PF05336.13 EMC93466.1 - 3.7e-36 123.5 0.2 4.2e-36 123.3 0.2 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Leader_Trp PF08255.11 EMC93466.1 - 3.4 7.9 5.9 38 4.6 2.1 2.7 2 0 0 2 2 2 0 Trp-operon Leader Peptide zf-H2C2_2 PF13465.6 EMC93468.1 - 1.1e-06 28.8 26.5 5.8e-05 23.3 3.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EMC93468.1 - 1.1e-05 25.6 14.0 0.00045 20.5 4.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EMC93468.1 - 0.019 15.2 0.4 0.054 13.8 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EMC93468.1 - 0.034 15.0 20.6 0.052 14.4 3.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMC93468.1 - 0.04 13.9 1.2 2.4 8.3 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 EMC93468.1 - 0.097 13.3 2.9 0.17 12.5 0.3 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 EMC93468.1 - 6.3 6.6 14.2 3.4 7.5 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Methyltransf_2 PF00891.18 EMC93470.1 - 1.3e-19 70.4 0.0 2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 EMC93470.1 - 0.00018 21.2 0.0 0.00044 20.0 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 EMC93470.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EMC93470.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 EMC93470.1 - 0.11 12.9 0.0 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator Hist_deacetyl PF00850.19 EMC93471.1 - 8.3e-54 183.1 0.2 2.4e-53 181.6 0.2 1.9 1 1 0 1 1 1 1 Histone deacetylase domain Peptidase_M76 PF09768.9 EMC93472.1 - 3.5e-65 219.0 0.3 4.2e-65 218.7 0.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EMC93472.1 - 0.012 15.5 2.6 0.017 15.0 1.0 1.9 1 1 1 2 2 2 0 SprT-like family Peptidase_M91 PF14891.6 EMC93472.1 - 0.04 14.2 0.0 0.059 13.7 0.0 1.2 1 0 0 1 1 1 0 Effector protein Peptidase_M90 PF06167.12 EMC93472.1 - 0.053 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Tox-MPTase2 PF15638.6 EMC93472.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 DUF2268 PF10026.9 EMC93472.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) RCDG1 PF15725.5 EMC93472.1 - 0.89 10.0 3.7 1.6 9.2 3.7 1.3 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Caskin-Pro-rich PF16907.5 EMC93472.1 - 5.8 7.5 5.7 12 6.5 5.7 1.5 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Pkinase PF00069.25 EMC93473.1 - 1.1e-68 231.5 0.0 1.4e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC93473.1 - 1.9e-42 145.3 0.0 2.6e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC93473.1 - 1.9e-06 27.4 0.0 7.8e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMC93473.1 - 0.0018 17.7 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMC93473.1 - 0.03 13.3 0.0 0.03 13.3 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Peptidase_M3 PF01432.20 EMC93474.1 - 1.5e-155 519.0 0.0 3e-155 518.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M3 Rhodanese PF00581.20 EMC93475.1 - 4e-11 43.4 0.0 5.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain TFA2_Winged_2 PF18121.1 EMC93475.1 - 0.072 12.8 0.1 0.46 10.2 0.0 2.3 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 MR_MLE_C PF13378.6 EMC93477.1 - 1.3e-55 188.4 0.0 1.9e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EMC93477.1 - 0.00071 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.16 EMC93477.1 - 0.15 12.3 0.1 0.99 9.6 0.0 2.3 3 0 0 3 3 3 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain GFA PF04828.14 EMC93478.1 - 1.3e-13 51.1 0.0 1.8e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Lon_C PF05362.13 EMC93479.1 - 3e-63 213.1 0.0 6.9e-63 211.9 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EMC93479.1 - 1.1e-33 116.9 0.0 2.8e-33 115.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EMC93479.1 - 1.1e-21 77.7 0.0 2.7e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMC93479.1 - 5.3e-07 29.7 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMC93479.1 - 3.4e-06 27.3 0.0 1.1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 EMC93479.1 - 5e-05 22.4 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain ChlI PF13541.6 EMC93479.1 - 5.1e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 EMC93479.1 - 5.9e-05 23.3 0.0 0.00071 19.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMC93479.1 - 8.6e-05 22.3 0.0 0.00057 19.7 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMC93479.1 - 0.00085 19.7 0.7 0.0061 17.0 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 EMC93479.1 - 0.0099 15.9 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain F-box-like_2 PF13013.6 EMC93479.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain IstB_IS21 PF01695.17 EMC93479.1 - 0.015 15.0 0.1 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein SKI PF01202.22 EMC93479.1 - 0.018 15.1 0.1 0.5 10.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_18 PF13238.6 EMC93479.1 - 0.022 15.3 1.5 0.12 12.9 0.0 2.8 4 0 0 4 4 2 0 AAA domain AAA_30 PF13604.6 EMC93479.1 - 0.036 13.8 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.9 EMC93479.1 - 0.039 14.0 1.4 0.1 12.6 0.3 2.3 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein RNA_helicase PF00910.22 EMC93479.1 - 0.089 13.2 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EMC93479.1 - 0.09 12.7 0.2 1 9.3 0.0 2.5 1 1 1 2 2 2 0 NTPase RsgA_GTPase PF03193.16 EMC93479.1 - 0.13 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EMC93479.1 - 0.25 10.8 1.0 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EMC93479.1 - 2.7 8.5 5.8 0.82 10.2 0.1 2.7 3 0 0 3 3 3 0 ABC transporter eIF3g PF12353.8 EMC93480.1 - 2e-39 134.8 1.9 2.7e-39 134.4 1.9 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EMC93480.1 - 2.2e-17 62.6 0.0 3.5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) M3 PF09213.10 EMC93482.1 - 0.11 11.2 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 M3 Fungal_trans_2 PF11951.8 EMC93483.1 - 7.2e-10 38.2 1.2 1.1e-09 37.6 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93483.1 - 1.5e-05 25.0 10.9 2.5e-05 24.3 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 EMC93484.1 - 2.2e-09 37.4 0.0 3.5e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC93484.1 - 2.9e-09 36.8 1.1 1e-08 35.0 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain FA_desaturase PF00487.24 EMC93485.1 - 1.9e-19 70.5 13.9 3.7e-19 69.6 13.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EMC93485.1 - 2.7e-16 59.5 0.1 7.7e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF1189 PF06691.11 EMC93485.1 - 0.069 12.7 2.2 0.51 9.9 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1189) AAA_12 PF13087.6 EMC93486.1 - 1e-21 77.5 0.0 1.4e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMC93486.1 - 0.00014 21.7 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EMC93486.1 - 0.0017 18.1 0.0 0.0057 16.5 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Cutinase PF01083.22 EMC93486.1 - 0.13 12.3 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Cutinase PhoH PF02562.16 EMC93487.1 - 0.00065 19.2 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 EMC93487.1 - 0.00071 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC93487.1 - 0.0037 17.7 0.0 0.0082 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EMC93487.1 - 0.036 14.5 0.2 0.062 13.7 0.2 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMC93487.1 - 0.058 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EMC93487.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EMC93487.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMC93487.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EMC93487.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 KaiC PIF1 PF05970.14 EMC93487.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase AAA_23 PF13476.6 EMC93487.1 - 0.21 12.1 0.0 0.74 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EMC93487.1 - 0.26 11.1 0.4 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain QWRF PF04484.12 EMC93488.1 - 7.6 6.2 17.0 6.3 6.4 8.1 2.2 2 0 0 2 2 2 0 QWRF family Fungal_trans_2 PF11951.8 EMC93489.1 - 1.3e-16 60.4 0.4 4.8e-11 42.1 1.2 3.0 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93489.1 - 1.4e-07 31.5 12.5 2.8e-07 30.6 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 EMC93490.1 - 4.4e-36 124.6 0.0 5.1e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC93490.1 - 1.6e-13 51.0 0.3 1.8e-13 50.8 0.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC93490.1 - 4.8e-06 26.2 0.1 5.4e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMC93490.1 - 0.094 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EMC93490.1 - 0.12 12.6 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 EMC93490.1 - 0.14 12.7 1.0 0.26 11.9 1.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EMC93490.1 - 0.17 12.0 0.1 0.39 10.8 0.2 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF4133 PF13571.6 EMC93491.1 - 0.12 12.7 3.1 3.3 8.1 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4133) PGI PF00342.19 EMC93492.1 - 6.9e-240 796.7 0.8 7.9e-240 796.5 0.8 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Abhydrolase_1 PF00561.20 EMC93494.1 - 5.2e-21 75.5 0.2 8.8e-21 74.7 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC93494.1 - 1.6e-17 64.9 2.4 4e-17 63.6 2.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC93494.1 - 1.3e-11 44.2 0.0 1.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMC93494.1 - 0.00071 19.1 0.1 0.022 14.2 0.0 2.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 EMC93494.1 - 0.017 14.2 0.0 0.032 13.2 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.13 EMC93494.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EMC93494.1 - 0.08 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Pkinase PF00069.25 EMC93495.1 - 4.5e-70 236.0 0.0 5.8e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC93495.1 - 3.5e-34 118.3 0.0 4.8e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EMC93495.1 - 2e-11 44.4 0.2 6e-11 42.9 0.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EMC93495.1 - 1.9e-06 27.1 0.0 2.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 EMC93495.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain FTA2 PF13095.6 EMC93495.1 - 0.008 15.8 0.1 0.34 10.5 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EMC93495.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like ZZ PF00569.17 EMC93496.1 - 1.5e-10 40.7 5.6 3.1e-10 39.7 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EMC93496.1 - 5.3e-08 32.9 0.0 1.4e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4615 PF15393.6 EMC93496.1 - 2.5 8.7 9.2 0.19 12.3 2.6 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4615) adh_short PF00106.25 EMC93498.1 - 1.1e-42 145.7 0.1 1.5e-42 145.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93498.1 - 1.6e-26 93.3 0.0 2.2e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC93498.1 - 1.8e-06 28.0 0.1 3.1e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMC93498.1 - 0.0007 18.8 0.0 0.00098 18.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ARTD15_N PF18084.1 EMC93498.1 - 0.034 14.4 0.1 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 ARTD15 N-terminal domain 3HCDH_N PF02737.18 EMC93498.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EMC93498.1 - 0.14 12.8 0.0 0.39 11.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EMC93498.1 - 0.15 12.2 0.1 0.36 10.9 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Erg28 PF03694.13 EMC93499.1 - 2e-45 153.7 0.3 2.5e-45 153.4 0.3 1.1 1 0 0 1 1 1 1 Erg28 like protein DHO_dh PF01180.21 EMC93500.1 - 1.1e-71 241.5 0.1 1.2e-71 241.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EMC93500.1 - 0.0062 15.6 0.1 0.48 9.4 0.2 2.5 2 1 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 EMC93500.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase Transketolase_N PF00456.21 EMC93501.1 - 1.4e-127 425.3 0.1 2.2e-127 424.6 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EMC93501.1 - 3.8e-35 121.2 0.0 8.9e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMC93501.1 - 1.4e-07 31.5 0.0 3.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 EMC93501.1 - 2.3e-07 30.1 0.1 4.1e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EMC93501.1 - 0.0001 21.6 0.0 0.00075 18.8 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase NAD_binding_11 PF14833.6 EMC93502.1 - 1.1e-35 122.5 1.1 1.1e-24 87.0 0.2 2.7 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EMC93502.1 - 5.7e-15 55.8 0.0 1.1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh PF00984.19 EMC93502.1 - 0.049 13.8 0.5 1 9.6 0.1 2.6 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain RTA1 PF04479.13 EMC93503.1 - 2.6e-65 219.9 4.0 2.6e-65 219.9 4.0 1.9 1 1 1 2 2 2 1 RTA1 like protein Dak2 PF02734.17 EMC93504.1 - 1.1e-45 155.6 4.4 1.5e-45 155.2 2.1 2.1 2 0 0 2 2 2 1 DAK2 domain Dak1 PF02733.17 EMC93504.1 - 0.0037 16.2 0.0 0.014 14.3 0.0 1.9 2 0 0 2 2 2 1 Dak1 domain Organ_specific PF10950.8 EMC93504.1 - 0.19 12.5 0.1 1.1 10.0 0.0 2.2 2 0 0 2 2 2 0 Organ specific protein ATP-synt_C PF00137.21 EMC93504.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.1 3 0 0 3 3 3 0 ATP synthase subunit C OsmC PF02566.19 EMC93505.1 - 8.8e-15 55.0 0.0 2.5e-14 53.6 0.0 1.7 1 1 1 2 2 2 1 OsmC-like protein Fungal_trans PF04082.18 EMC93507.1 - 5.1e-15 55.2 0.1 9.3e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EMC93507.1 - 6.2e-07 29.6 9.0 5.3e-05 23.5 3.5 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 EMC93507.1 - 0.00069 19.9 5.4 0.0016 18.7 5.4 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EMC93507.1 - 0.0013 19.4 17.1 0.04 14.8 5.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EMC93507.1 - 0.065 13.7 16.8 0.26 11.8 7.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 EMC93507.1 - 7.2 7.2 6.7 9.3 6.8 0.8 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type BIR PF00653.21 EMC93508.1 - 0.019 15.6 0.0 0.049 14.3 0.0 1.7 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain SLAC1 PF03595.17 EMC93509.1 - 6e-82 275.5 43.1 6.8e-82 275.3 43.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Phosphodiest PF01663.22 EMC93510.1 - 5e-85 286.2 0.0 6.9e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMC93510.1 - 3.3e-05 23.5 0.0 0.047 13.1 0.0 2.3 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 EMC93510.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily CDC45 PF02724.14 EMC93510.1 - 0.15 10.4 1.8 0.2 9.9 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.29 EMC93511.1 - 1.5e-40 138.7 0.0 2.6e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMC93511.1 - 7.7e-05 22.7 0.1 0.00062 19.8 0.0 2.5 4 1 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMC93511.1 - 8.2e-05 22.9 0.0 0.0059 16.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 EMC93511.1 - 0.00012 21.8 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EMC93511.1 - 0.00044 20.4 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EMC93511.1 - 0.00055 20.4 0.1 0.011 16.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EMC93511.1 - 0.0016 17.6 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EMC93511.1 - 0.0095 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EMC93511.1 - 0.033 14.5 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMC93511.1 - 0.037 14.4 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 EMC93511.1 - 0.038 13.5 0.0 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EMC93511.1 - 0.052 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMC93511.1 - 0.068 12.9 0.1 0.27 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EMC93511.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EMC93511.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMC93511.1 - 0.15 12.6 0.0 0.49 11.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 EMC93511.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 EMC93512.1 - 5.1e-143 477.2 2.9 5.8e-143 477.1 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 EMC93512.1 - 0.016 14.8 0.2 0.049 13.3 0.0 1.9 2 0 0 2 2 2 0 Phage Tail Protein X DUF1077 PF06417.12 EMC93513.1 - 1.9e-49 166.6 2.1 2.2e-49 166.4 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Spore_YtrH PF14034.6 EMC93513.1 - 0.0074 16.4 0.3 0.0095 16.1 0.3 1.1 1 0 0 1 1 1 1 Sporulation protein YtrH Adaptin_N PF01602.20 EMC93514.1 - 1.4e-121 406.7 10.4 1.8e-121 406.3 10.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EMC93514.1 - 2.2e-56 190.4 5.6 4.1e-56 189.5 0.4 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMC93514.1 - 5e-16 58.9 7.1 5.2e-05 23.5 0.1 5.1 4 1 0 5 5 5 4 HEAT repeats HEAT PF02985.22 EMC93514.1 - 3.6e-11 42.3 4.2 0.0013 18.8 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 EMC93514.1 - 6.6e-05 23.3 4.9 2.8 8.5 0.3 5.3 4 1 1 5 5 5 2 HEAT-like repeat CLASP_N PF12348.8 EMC93514.1 - 0.00017 21.2 0.3 0.75 9.3 0.0 3.0 2 1 0 2 2 2 2 CLASP N terminal DNA_alkylation PF08713.11 EMC93514.1 - 0.00082 19.1 0.4 5.6 6.6 0.2 3.9 2 2 2 4 4 4 2 DNA alkylation repair enzyme RTP1_C1 PF10363.9 EMC93514.1 - 0.0019 18.3 3.6 0.19 11.9 0.1 3.5 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RICTOR_N PF14664.6 EMC93514.1 - 0.016 14.2 8.5 3 6.8 0.1 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term DUF2496 PF10689.9 EMC93514.1 - 0.13 12.1 0.4 0.57 10.0 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2496) Arm PF00514.23 EMC93514.1 - 0.51 10.5 5.5 69 3.7 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ACPS PF01648.20 EMC93515.1 - 8.5e-12 45.2 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EMC93515.1 - 0.041 14.0 0.8 6.6 6.9 0.2 2.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain T5orf172 PF10544.9 EMC93517.1 - 1.3e-10 41.7 0.0 4.3e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EMC93517.1 - 1.9e-05 25.2 0.0 6.2e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 Ran_BP1 PF00638.18 EMC93518.1 - 2.2e-15 57.0 0.0 3.8e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Keratin_2_head PF16208.5 EMC93518.1 - 2.3 8.4 43.5 0.32 11.1 8.3 2.4 2 0 0 2 2 2 0 Keratin type II head ArfGap PF01412.18 EMC93519.1 - 9.6e-35 119.2 0.4 1.7e-34 118.4 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PROL5-SMR PF15621.6 EMC93519.1 - 1.6 9.3 7.0 0.85 10.2 1.5 2.3 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF2415 PF10313.9 EMC93520.1 - 4.8e-14 52.0 0.0 8.6e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 EMC93520.1 - 0.037 14.3 0.0 21 5.5 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EMC93520.1 - 0.12 12.9 2.8 23 5.6 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Lgl_C PF08596.10 EMC93520.1 - 0.21 10.2 0.0 0.66 8.6 0.0 1.7 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EMC93520.1 - 0.22 12.4 1.4 43 5.2 0.1 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Mannitol_dh_C PF08125.13 EMC93521.1 - 4e-43 147.7 1.0 5.6e-43 147.2 0.2 1.6 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EMC93521.1 - 2.6e-18 66.6 1.7 6.1e-18 65.4 0.1 2.1 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 EMC93521.1 - 0.00033 20.6 0.2 0.00033 20.6 0.2 2.2 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain S19 PF06756.11 EMC93521.1 - 0.0084 16.0 0.0 5.8 6.9 0.0 2.6 2 0 0 2 2 2 2 Chorion protein S19 C-terminal UDPG_MGDP_dh_N PF03721.14 EMC93521.1 - 0.19 11.3 2.1 0.17 11.4 0.5 1.8 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EMC93521.1 - 0.41 11.3 2.0 1.3 9.7 0.2 2.6 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Choline_transpo PF04515.12 EMC93522.1 - 3.3e-86 289.4 21.8 3.3e-86 289.4 21.8 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter tRNA-synt_2 PF00152.20 EMC93523.1 - 2.2e-69 233.9 0.0 4.1e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EMC93523.1 - 3.9e-16 58.9 0.0 6e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EMC93523.1 - 3.7e-08 33.3 0.0 7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMC93523.1 - 0.00013 21.5 0.4 0.52 9.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) STI1 PF17830.1 EMC93523.1 - 0.02 14.8 1.5 0.031 14.2 0.3 2.0 2 0 0 2 2 2 0 STI1 domain DUF3486 PF11985.8 EMC93523.1 - 0.1 13.0 2.9 0.24 11.8 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) ARGLU PF15346.6 EMC93523.1 - 0.66 9.8 11.4 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Prp19 PF08606.11 EMC93523.1 - 1.2 9.2 3.2 3.3 7.8 3.2 1.7 1 0 0 1 1 1 0 Prp19/Pso4-like Noggin PF05806.12 EMC93523.1 - 8.5 6.2 5.5 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Noggin Kv2channel PF03521.14 EMC93524.1 - 0.018 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel Acyltransferase PF01553.21 EMC93525.1 - 4.2e-16 58.8 0.0 6.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EMC93525.1 - 3.7e-07 30.1 0.3 3.7e-07 30.1 0.3 1.7 2 0 0 2 2 2 1 Acyltransferase C-terminus TF_Zn_Ribbon PF08271.12 EMC93526.1 - 0.0078 15.7 1.5 0.66 9.5 0.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding AAA_18 PF13238.6 EMC93527.1 - 0.0068 16.9 0.0 0.017 15.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EMC93527.1 - 0.016 15.4 0.0 0.036 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMC93527.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 EMC93527.1 - 0.047 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EMC93527.1 - 0.066 13.6 0.0 0.33 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 EMC93527.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EMC93527.1 - 0.081 13.2 0.0 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EMC93527.1 - 0.096 11.9 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 EMC93527.1 - 0.11 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EMC93527.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.6 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 EMC93527.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 EMC93527.1 - 0.18 10.7 0.4 0.42 9.6 0.2 1.5 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cys_Met_Meta_PP PF01053.20 EMC93528.1 - 7.1e-120 400.0 0.1 3.6e-108 361.5 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMC93528.1 - 0.0064 15.5 0.0 0.032 13.2 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V adh_short PF00106.25 EMC93529.1 - 6.5e-84 280.2 13.3 1.3e-44 152.0 2.2 2.9 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93529.1 - 8.6e-66 221.8 6.8 8.4e-35 120.4 1.2 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EMC93529.1 - 2.3e-33 114.4 0.0 5.9e-33 113.1 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain KR PF08659.10 EMC93529.1 - 1.1e-30 106.9 3.8 1.9e-14 54.0 0.3 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 EMC93529.1 - 0.00039 20.6 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Epimerase PF01370.21 EMC93529.1 - 0.19 11.2 1.5 7.3 6.0 0.2 2.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMC93530.1 - 1.6e-39 135.4 0.0 2e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93530.1 - 1.6e-19 70.4 0.0 2.1e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC93530.1 - 3.4e-09 36.9 0.0 7.9e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC93530.1 - 9.6e-05 21.9 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC93530.1 - 0.0014 17.9 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 EMC93530.1 - 0.02 15.5 0.1 0.044 14.4 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EMC93530.1 - 0.04 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMC93530.1 - 0.079 12.8 0.1 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EMC93530.1 - 0.098 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EMC93530.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMC93530.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Chitin_synth_1 PF01644.17 EMC93531.1 - 3.8e-78 261.1 0.1 5.8e-78 260.5 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EMC93531.1 - 3.3e-27 94.3 0.1 7.4e-27 93.1 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EMC93531.1 - 3.8e-24 85.2 1.6 7.9e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EMC93531.1 - 8.2e-07 29.1 1.1 8.2e-07 29.1 1.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMC93531.1 - 0.001 19.0 0.0 0.029 14.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 EAP30 PF04157.16 EMC93532.1 - 1.7e-41 142.1 0.0 2.2e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EMC93532.1 - 4.6e-24 84.4 0.0 7.3e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 EMC93532.1 - 6.5e-22 76.7 1.1 6.5e-22 76.7 1.1 2.8 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EMC93532.1 - 6.9e-05 22.8 4.8 0.01 15.8 0.2 2.7 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 EMC93532.1 - 0.0001 21.5 7.2 0.008 15.5 1.1 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 EMC93532.1 - 0.011 15.7 5.0 0.032 14.3 0.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon GRAM PF02893.20 EMC93532.1 - 0.21 11.4 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 GRAM domain Rubredoxin PF00301.20 EMC93532.1 - 1.9 8.6 8.1 1.3 9.1 0.1 3.3 3 1 0 3 3 3 0 Rubredoxin SAC3_GANP PF03399.16 EMC93533.1 - 1.3e-23 83.8 2.1 1e-21 77.6 2.1 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EMC93533.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family SH3_1 PF00018.28 EMC93534.1 - 3.1e-23 81.1 0.0 4.2e-11 42.3 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EMC93534.1 - 7.8e-14 51.3 1.1 5e-06 26.3 0.1 2.8 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 EMC93534.1 - 4.3e-13 49.2 0.0 1.2e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EMC93534.1 - 1.1e-10 41.0 0.0 8.3e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain HSP70 PF00012.20 EMC93535.1 - 4.1e-265 880.6 15.4 4.7e-265 880.4 15.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMC93535.1 - 1.5e-13 50.3 4.0 3.1e-12 46.0 1.7 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EMC93535.1 - 4.1e-06 26.6 0.0 1.5e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Glyoxalase_4 PF13669.6 EMC93535.1 - 0.14 12.4 0.0 0.63 10.3 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YlbD_coat PF14071.6 EMC93535.1 - 1.8 8.8 5.4 2.9 8.1 3.9 2.1 2 0 0 2 2 2 0 Putative coat protein Carb_kinase PF01256.17 EMC93537.1 - 6.1e-57 192.9 0.0 7.5e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EMC93537.1 - 0.00038 19.9 0.1 0.0019 17.6 0.1 1.9 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase HK PF02110.15 EMC93537.1 - 0.0088 15.5 0.0 0.018 14.5 0.0 1.4 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Abhydrolase_1 PF00561.20 EMC93539.1 - 2.9e-17 63.2 0.0 1.1e-16 61.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC93539.1 - 3.4e-13 50.7 0.0 4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC93539.1 - 3e-12 46.3 0.0 6.3e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMC93539.1 - 0.0011 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 EMC93539.1 - 0.022 14.4 0.0 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) AATase PF07247.12 EMC93540.1 - 0.055 12.0 0.0 0.084 11.4 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase Kinesin PF00225.23 EMC93541.1 - 5.7e-110 367.4 0.0 9.2e-110 366.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 EMC93541.1 - 1.9e-38 132.6 0.6 1.8e-37 129.3 0.0 2.5 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 EMC93541.1 - 1.3e-37 129.7 9.8 6.6e-31 107.8 0.3 3.0 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 EMC93541.1 - 9.7e-25 87.3 0.0 2.8e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 EMC93541.1 - 0.00012 22.6 0.1 0.00033 21.1 0.1 1.8 1 0 0 1 1 1 1 PH domain FHA PF00498.26 EMC93541.1 - 0.0003 21.1 0.1 0.0019 18.5 0.0 2.4 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 EMC93541.1 - 0.018 15.4 0.2 0.05 14.0 0.2 1.8 1 0 0 1 1 1 0 Kinesin protein 1B ADH_zinc_N_2 PF13602.6 EMC93541.1 - 0.15 13.2 0.3 1.6e+02 3.3 0.0 3.8 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Met_10 PF02475.16 EMC93542.1 - 4e-67 225.8 0.0 6.8e-67 225.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 EMC93543.1 - 9.4e-11 42.2 0.0 1.7e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC93543.1 - 1.1e-10 42.1 0.1 2.6e-10 40.9 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC93543.1 - 2e-06 27.3 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMC93543.1 - 4.4e-06 27.3 0.0 6.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC93543.1 - 0.00065 19.6 0.0 0.00079 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC93543.1 - 0.0021 17.9 0.0 0.0039 17.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Beta_elim_lyase PF01212.21 EMC93544.1 - 3.6e-66 223.4 0.0 4.4e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EMC93544.1 - 4.4e-05 22.2 0.0 8.4e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-C2H2 PF00096.26 EMC93545.1 - 8.2e-05 22.8 44.2 0.088 13.3 8.5 7.1 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC93545.1 - 0.13 13.2 0.5 0.13 13.2 0.5 7.9 9 0 0 9 9 9 0 C2H2-type zinc finger eIF3m_C_helix PF18005.1 EMC93547.1 - 0.093 12.4 0.7 0.093 12.4 0.7 2.1 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix ELMO_CED12 PF04727.13 EMC93548.1 - 1.4e-41 142.5 0.0 2.9e-41 141.5 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 EMC93548.1 - 1.4e-32 113.0 0.2 2.5e-32 112.2 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EMC93548.1 - 3.8e-10 39.9 0.0 9.1e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) GlyL_C PF12524.8 EMC93548.1 - 0.17 12.1 0.2 0.29 11.3 0.2 1.4 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal DUF1752 PF08550.10 EMC93549.1 - 6.3e-10 38.7 4.2 1.3e-09 37.7 4.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) HET PF06985.11 EMC93552.1 - 4.2e-27 95.3 0.0 1.2e-26 93.8 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kelch_3 PF13415.6 EMC93553.1 - 2.9e-30 103.9 7.4 1.2e-07 31.8 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EMC93553.1 - 1.5e-26 92.1 8.4 4.6e-14 52.2 0.0 6.7 4 2 2 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EMC93553.1 - 1.6e-15 56.4 11.3 0.016 14.8 0.0 7.1 6 2 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EMC93553.1 - 8.3e-14 51.3 6.0 0.026 14.8 0.0 7.0 5 2 1 6 6 6 4 Kelch motif Kelch_5 PF13854.6 EMC93553.1 - 1e-11 44.5 2.2 0.0029 17.5 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 EMC93553.1 - 7.2e-09 35.3 8.0 0.06 13.3 0.1 6.8 6 2 0 6 6 6 3 Kelch motif KRE9 PF05390.11 EMC93554.1 - 2.9e-17 63.3 7.1 2.9e-17 63.3 7.1 2.0 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 EMC93554.1 - 3.2e-14 53.4 2.3 8.3e-14 52.1 0.3 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_M24 PF00557.24 EMC93555.1 - 9.7e-58 195.3 0.0 1.2e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EMC93555.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 EMC93555.1 - 0.092 12.8 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) Peptidase_A4 PF01828.17 EMC93556.1 - 3.8e-77 258.5 17.7 4.5e-77 258.2 17.7 1.0 1 0 0 1 1 1 1 Peptidase A4 family Mit_ribos_Mrp51 PF11709.8 EMC93559.1 - 6.8e-120 401.0 0.4 8.4e-120 400.7 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit CDC27 PF09507.10 EMC93560.1 - 0.27 10.6 0.1 0.36 10.2 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pilin_GH PF16734.5 EMC93560.1 - 3 8.2 16.0 0.36 11.2 6.9 2.5 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative Aconitase PF00330.20 EMC93562.1 - 4.2e-164 546.9 0.0 5.5e-164 546.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMC93562.1 - 2.9e-40 137.6 0.0 7e-40 136.4 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain Peptidase_M28 PF04389.17 EMC93563.1 - 1.3e-31 109.8 0.0 2.5e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EMC93563.1 - 1.3e-05 25.1 0.1 2.9e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 SPC25 PF06703.11 EMC93564.1 - 2.3e-51 173.8 0.0 2.6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) EMC3_TMCO1 PF01956.16 EMC93565.1 - 1.8e-54 184.0 0.1 2.8e-54 183.4 0.1 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like adh_short PF00106.25 EMC93566.1 - 0.00034 20.1 0.0 0.00059 19.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Med26 PF08711.11 EMC93567.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain TPR_1 PF00515.28 EMC93568.1 - 1.6e-21 75.1 2.4 3.2e-07 29.9 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMC93568.1 - 7.4e-20 69.4 4.9 1.5e-05 24.7 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EMC93568.1 - 1.4e-17 63.1 1.6 1.5e-07 31.0 0.0 4.5 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.6 EMC93568.1 - 2.1e-17 61.8 1.0 0.00034 20.6 0.0 5.2 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 EMC93568.1 - 7.5e-15 55.3 12.4 6e-06 26.8 0.4 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 EMC93568.1 - 1.1e-11 44.8 3.9 0.00041 20.6 1.5 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMC93568.1 - 6.7e-11 42.1 11.0 0.0001 22.8 0.6 5.3 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMC93568.1 - 8.3e-11 42.2 7.0 0.0019 18.7 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMC93568.1 - 1.3e-10 40.5 6.6 0.048 13.7 0.1 5.7 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMC93568.1 - 1.6e-09 37.5 0.6 1.7 9.2 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMC93568.1 - 2.6e-06 27.5 7.8 0.019 15.1 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EMC93568.1 - 4.5e-06 26.9 4.1 0.017 15.5 0.0 4.3 4 2 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC93568.1 - 6.8e-06 26.2 1.3 4.9e-05 23.5 0.2 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EMC93568.1 - 1.2e-05 25.6 6.2 10 7.0 0.1 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EMC93568.1 - 0.00038 20.4 0.0 1.7 8.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 EMC93568.1 - 0.00058 19.2 1.8 0.27 10.4 0.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 EMC93568.1 - 0.015 15.3 0.8 3.7 7.7 0.0 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Bac_luciferase PF00296.20 EMC93568.1 - 0.016 14.6 1.1 0.075 12.4 1.1 2.1 1 1 0 1 1 1 0 Luciferase-like monooxygenase PYRIN PF02758.16 EMC93568.1 - 0.13 12.4 0.1 5.6 7.2 0.0 2.6 1 1 1 2 2 2 0 PAAD/DAPIN/Pyrin domain BTAD PF03704.17 EMC93568.1 - 0.23 11.9 7.2 16 5.9 0.1 4.3 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 EMC93568.1 - 0.33 11.1 1.2 15 5.7 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EMC93568.1 - 0.34 10.8 9.0 2.1 8.4 0.5 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 EMC93569.1 - 2.5e-33 113.7 0.6 4.7e-17 61.6 0.1 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EMC93569.1 - 0.0011 19.0 0.1 1.4 9.0 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 EMC93569.1 - 0.011 15.3 0.0 0.17 11.5 0.0 2.3 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EMC93569.1 - 0.16 11.9 0.2 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 EMC93569.1 - 0.16 11.6 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Ndc1_Nup PF09531.10 EMC93569.1 - 0.67 8.6 6.4 0.73 8.4 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RIFIN PF02009.16 EMC93569.1 - 3 7.6 5.7 5.5 6.8 5.7 1.4 1 0 0 1 1 1 0 Rifin GREB1 PF15782.5 EMC93569.1 - 4.3 4.3 10.3 5.4 4.0 10.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer STT3 PF02516.14 EMC93570.1 - 3.6e-142 474.7 34.0 1.8e-138 462.5 31.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit MFS_1 PF07690.16 EMC93571.1 - 2.1e-35 122.3 29.8 2.1e-35 122.3 29.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EMC93571.1 - 0.0058 16.4 5.0 3.3 7.5 4.3 2.7 2 1 1 3 3 3 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1_like PF12832.7 EMC93571.1 - 0.048 12.5 12.9 0.14 11.0 12.9 2.1 1 1 0 1 1 1 0 MFS_1 like family HET PF06985.11 EMC93573.1 - 1.8e-26 93.2 1.9 2e-26 93.1 1.9 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 EMC93575.1 - 3e-19 69.2 5.0 3.8e-19 68.9 5.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC93575.1 - 6.8e-15 54.8 12.1 9.4e-15 54.4 12.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Tannase PF07519.11 EMC93577.1 - 1.8e-105 353.6 0.4 2.6e-105 353.0 0.4 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EMC93577.1 - 2.7e-05 23.5 0.0 0.00044 19.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 SpoIIE PF07228.12 EMC93578.1 - 9.1e-10 38.8 2.0 3.5e-09 36.8 2.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EMC93578.1 - 4e-08 33.2 0.1 0.0039 16.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EMC93578.1 - 0.0017 18.0 2.5 0.003 17.2 2.5 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Cupin_6 PF12852.7 EMC93578.1 - 0.0082 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Cupin bZIP_1 PF00170.21 EMC93581.1 - 8.1e-10 38.7 10.2 8.1e-10 38.7 10.2 3.1 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 EMC93581.1 - 1.4e-06 28.3 8.3 1.4e-06 28.3 8.3 3.1 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMC93581.1 - 4.4e-06 27.1 10.8 4.4e-06 27.1 10.8 3.3 3 1 1 4 4 4 1 bZIP Maf transcription factor Tho2 PF11262.8 EMC93581.1 - 0.39 9.9 6.5 0.32 10.1 5.2 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FapA PF03961.13 EMC93581.1 - 1.8 7.1 7.3 3 6.4 7.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sel1 PF08238.12 EMC93582.1 - 2.2e-13 50.4 8.3 0.00036 21.1 0.1 4.1 4 0 0 4 4 4 3 Sel1 repeat zf-CCCH PF00642.24 EMC93583.1 - 1.7e-14 53.3 23.8 6.4e-05 22.8 3.3 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EMC93583.1 - 2.7e-13 49.5 28.6 0.00036 20.5 0.1 6.0 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 EMC93583.1 - 0.001 18.8 4.8 0.014 15.2 2.9 5.0 5 1 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EMC93583.1 - 0.0073 16.5 2.7 0.0073 16.5 2.7 3.2 2 1 1 3 3 3 2 Zinc-finger containing family Torus PF16131.5 EMC93583.1 - 0.26 12.0 27.3 2.9 8.6 0.1 5.0 2 1 3 5 5 5 0 Torus domain WD40 PF00400.32 EMC93584.1 - 2.1e-32 110.6 14.3 5.8e-07 30.1 0.3 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat PRP4 PF08799.11 EMC93584.1 - 7.6e-12 44.6 8.4 1.4e-11 43.7 8.4 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EMC93584.1 - 2.3e-08 34.2 0.0 0.36 11.1 0.0 4.7 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMC93584.1 - 0.0054 16.6 0.0 15 5.4 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ribosomal_S8e PF01201.22 EMC93587.1 - 2e-46 157.6 3.0 3e-46 157.0 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Red1 PF07964.11 EMC93587.1 - 0.65 8.2 9.9 0.74 8.0 9.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Pannexin_like PF12534.8 EMC93587.1 - 3.9 6.5 5.8 5.5 6.0 5.8 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 IATP PF04568.12 EMC93587.1 - 4 7.9 10.7 3.1 8.3 8.8 1.9 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Ribosomal_L21p PF00829.21 EMC93588.1 - 1.4e-05 25.3 0.1 2.4e-05 24.5 0.1 1.4 1 1 0 1 1 1 1 Ribosomal prokaryotic L21 protein Sortilin-Vps10 PF15902.5 EMC93590.1 - 3.5e-293 972.0 10.1 4.9e-153 510.1 3.7 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EMC93590.1 - 8.4e-91 302.9 15.9 5.3e-46 157.1 3.7 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal Pyr_redox_2 PF07992.14 EMC93590.1 - 6.8e-33 114.1 0.0 1.8e-32 112.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase BNR PF02012.20 EMC93590.1 - 6e-16 55.8 31.8 1.1 9.6 0.1 11.5 10 0 0 10 10 10 6 BNR/Asp-box repeat Pyr_redox PF00070.27 EMC93590.1 - 2.3e-13 50.5 0.9 8e-10 39.1 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase PSII_BNR PF14870.6 EMC93590.1 - 3.8e-10 39.5 5.2 5.3e-05 22.6 0.2 3.7 4 0 0 4 4 4 3 Photosynthesis system II assembly factor YCF48 Pyr_redox_3 PF13738.6 EMC93590.1 - 1.9e-06 27.3 0.0 2.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC93590.1 - 0.0023 17.2 0.1 0.0046 16.2 0.1 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EMC93590.1 - 0.015 15.6 1.6 2.1 8.6 0.1 3.1 3 0 0 3 3 3 0 TrkA-N domain DAO PF01266.24 EMC93590.1 - 0.032 13.8 0.2 3.1 7.3 0.0 2.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase CHB_HEX_C PF03174.13 EMC93590.1 - 0.034 14.1 4.8 5 7.2 0.1 5.2 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain THF_DHG_CYH_C PF02882.19 EMC93590.1 - 0.06 12.7 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ThiF PF00899.21 EMC93590.1 - 0.15 11.4 0.2 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 ThiF family BNR_6 PF15899.5 EMC93590.1 - 5.7 7.3 8.7 2.3e+02 2.3 0.0 6.0 6 0 0 6 6 5 0 BNR-Asp box repeat EGF_2 PF07974.13 EMC93592.1 - 0.6 10.5 4.3 17 5.9 0.6 2.5 2 0 0 2 2 2 0 EGF-like domain SUR7 PF06687.12 EMC93593.1 - 9.1e-17 61.4 0.0 1.4e-15 57.5 0.0 2.0 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EMC93593.1 - 0.0031 17.5 10.0 0.0031 17.5 10.0 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 E1-E2_ATPase PF00122.20 EMC93593.1 - 9.9 5.6 10.3 0.24 10.9 2.8 2.0 3 0 0 3 3 3 0 E1-E2 ATPase Pkinase PF00069.25 EMC93597.1 - 3.5e-58 197.1 0.0 6.3e-37 127.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMC93597.1 - 5.1e-27 94.8 0.0 5.1e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EMC93597.1 - 4.6e-13 49.3 0.0 9.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EMC93597.1 - 1.8e-08 34.1 0.0 1e-05 25.0 0.0 3.2 3 0 0 3 3 3 1 Kinase-like PAS PF00989.25 EMC93597.1 - 2.7e-05 24.1 0.0 7.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold APH PF01636.23 EMC93597.1 - 6.1e-05 23.0 0.0 0.003 17.5 0.1 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_4 PF08448.10 EMC93597.1 - 0.0011 19.2 0.0 0.0034 17.6 0.0 1.9 1 0 0 1 1 1 1 PAS fold Kdo PF06293.14 EMC93597.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EMC93597.1 - 0.017 14.2 0.1 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EMC93597.1 - 0.07 12.1 0.1 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PAS_9 PF13426.7 EMC93597.1 - 0.2 11.9 0.0 0.57 10.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain Pkinase_C PF00433.24 EMC93597.1 - 8.4 7.2 6.3 41 5.0 3.9 3.5 2 1 0 2 2 2 0 Protein kinase C terminal domain RNA_pol_Rpb4 PF03874.16 EMC93598.1 - 2.2e-17 63.5 0.0 2.9e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 RhoGAP PF00620.27 EMC93599.1 - 3.5e-37 127.6 0.0 8.9e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EMC93599.1 - 2.6e-27 94.8 39.8 7.6e-12 45.3 4.4 5.0 5 0 0 5 5 5 4 LIM domain Siva PF05458.12 EMC93599.1 - 4.2 7.0 20.3 1.1 8.9 7.4 3.1 3 0 0 3 3 3 0 Cd27 binding protein (Siva) COesterase PF00135.28 EMC93600.1 - 4.4e-68 230.4 0.0 7.4e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC93600.1 - 7.3e-10 39.1 0.2 4.2e-09 36.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC93600.1 - 0.034 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family GPI-anchored PF10342.9 EMC93601.1 - 1.1e-09 38.9 0.1 1.1e-09 38.9 0.1 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MGC-24 PF05283.11 EMC93601.1 - 3.7 8.0 20.4 53 4.3 20.4 2.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GPI-anchored PF10342.9 EMC93602.1 - 1.2e-07 32.4 0.3 2.6e-07 31.3 0.2 1.6 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ASH PF15780.5 EMC93602.1 - 0.01 16.0 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Prenyltransf PF01255.19 EMC93603.1 - 0.00014 21.5 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3112 PF11309.8 EMC93604.1 - 0.033 13.6 0.1 0.036 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) RRM_1 PF00076.22 EMC93607.1 - 2.2e-42 142.7 0.1 1.4e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC93607.1 - 7e-08 32.5 0.1 0.0034 17.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EMC93607.1 - 0.0064 16.1 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3973 PF13119.6 EMC93608.1 - 0.12 12.4 1.4 6.7 6.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) Alg6_Alg8 PF03155.15 EMC93611.1 - 2.6e-121 406.0 23.8 3.8e-76 257.0 9.5 2.3 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.13 EMC93612.1 - 3.2e-21 75.4 6.0 3.9e-21 75.1 6.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 EMC93612.1 - 0.043 14.0 2.8 0.068 13.3 2.8 1.4 1 0 0 1 1 1 0 CHCH domain LRR_6 PF13516.6 EMC93613.1 - 7e-13 47.5 4.5 0.078 13.1 0.0 8.0 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 EMC93613.1 - 1.5e-07 31.6 12.0 0.25 11.8 0.2 5.9 4 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMC93613.1 - 0.0012 19.1 1.5 16 6.5 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EMC93613.1 - 0.12 12.1 9.7 9.4 6.1 0.0 4.9 3 2 0 3 3 3 0 Leucine rich repeat SnoaL_4 PF13577.6 EMC93616.1 - 1.2e-26 93.3 0.1 1.5e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EMC93616.1 - 0.0001 22.8 0.4 0.00015 22.3 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EMC93616.1 - 0.013 15.9 0.2 0.017 15.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SKG6 PF08693.10 EMC93618.1 - 1.4e-05 24.4 0.0 1.4e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EMC93618.1 - 0.0046 16.7 0.1 0.0083 15.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 EMC93618.1 - 0.2 12.6 0.0 0.47 11.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SCF PF02404.15 EMC93618.1 - 0.47 9.7 3.4 0.12 11.7 0.3 1.5 1 1 0 1 1 1 0 Stem cell factor SOG2 PF10428.9 EMC93618.1 - 6.5 5.8 24.8 0.12 11.6 18.1 1.4 2 0 0 2 2 2 0 RAM signalling pathway protein Peptidase_M1 PF01433.20 EMC93619.1 - 1.1e-42 146.0 0.8 1.6e-42 145.6 0.8 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EMC93619.1 - 1.1e-37 128.6 0.0 2.3e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EMC93619.1 - 3.8e-28 99.0 0.0 5.9e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 EMC93619.1 - 0.046 13.4 0.1 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 EMC93619.1 - 0.39 11.1 3.6 4 7.9 2.4 2.8 2 1 0 2 2 2 0 M61 glycyl aminopeptidase ORC4_C PF14629.6 EMC93620.1 - 5.2e-42 143.7 0.0 9.2e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EMC93620.1 - 3.3e-13 50.4 0.9 1.3e-12 48.4 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMC93620.1 - 2.2e-08 34.4 0.5 8.9e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMC93620.1 - 1e-05 25.5 0.0 5.4e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 EMC93620.1 - 5.4e-05 23.6 0.0 0.00018 21.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EMC93620.1 - 0.00035 19.9 0.0 0.00074 18.9 0.0 1.6 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.13 EMC93620.1 - 0.00052 19.2 0.0 0.00098 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 EMC93620.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 EMC93620.1 - 0.0028 17.6 0.0 0.01 15.8 0.0 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EMC93620.1 - 0.0046 17.0 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 EMC93620.1 - 0.022 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 EMC93620.1 - 0.024 15.0 0.0 0.06 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMC93620.1 - 0.024 14.4 0.1 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EMC93620.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EMC93620.1 - 0.14 12.3 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase FAD_binding_3 PF01494.19 EMC93621.1 - 8.2e-29 100.9 0.1 1e-28 100.6 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC93621.1 - 2.9e-09 37.0 0.4 1.2e-06 28.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC93621.1 - 1.1e-07 31.4 2.8 7.3e-05 22.1 0.2 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC93621.1 - 7.7e-07 29.3 0.0 7.2e-06 26.1 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC93621.1 - 7.2e-05 23.3 8.4 0.00028 21.4 0.1 3.4 3 1 1 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC93621.1 - 7.7e-05 21.7 1.9 0.075 11.9 0.4 2.9 1 1 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 EMC93621.1 - 0.00015 21.0 0.5 0.0014 17.8 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EMC93621.1 - 0.00017 20.8 0.9 0.00032 19.9 0.2 1.7 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.17 EMC93621.1 - 0.00041 19.7 0.3 0.0006 19.1 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EMC93621.1 - 0.00077 18.8 0.4 0.42 9.8 0.1 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMC93621.1 - 0.00095 19.1 0.1 0.0021 17.9 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EMC93621.1 - 0.00095 18.0 0.2 0.01 14.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.16 EMC93621.1 - 0.001 18.7 0.1 0.0024 17.5 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EMC93621.1 - 0.001 18.7 1.7 0.042 13.4 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EMC93621.1 - 0.021 14.1 0.1 0.046 13.0 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EMC93621.1 - 0.051 13.7 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 EMC93621.1 - 0.057 12.5 0.2 0.15 11.1 0.2 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein CREPT PF16566.5 EMC93621.1 - 0.061 13.5 0.7 0.14 12.3 0.0 1.8 3 0 0 3 3 2 0 Cell-cycle alteration and expression-elevated protein in tumour Sacchrp_dh_NADP PF03435.18 EMC93621.1 - 0.098 12.9 0.3 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_oxidored PF12831.7 EMC93621.1 - 0.11 11.8 1.0 1 8.7 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EMC93621.1 - 0.13 12.7 0.2 0.28 11.6 0.2 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding bHLH-MYC_N PF14215.6 EMC93624.1 - 0.26 11.6 0.5 0.86 9.9 0.5 1.9 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal CrgA PF06781.12 EMC93624.1 - 1.1 9.3 2.8 1 9.5 0.1 2.3 2 1 1 3 3 3 0 Cell division protein CrgA DUF4112 PF13430.6 EMC93624.1 - 2.7 8.3 7.6 0.7 10.2 1.8 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4112) DUF2418 PF10332.9 EMC93626.1 - 9.3e-32 109.4 0.0 2.7e-31 108.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Gsf2 PF11055.8 EMC93627.1 - 0.0029 16.4 0.0 0.0033 16.2 0.0 1.1 1 0 0 1 1 1 1 Glucose signalling factor 2 Gon7 PF08738.10 EMC93627.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 Gon7 family Yip1 PF04893.17 EMC93629.1 - 1.4e-13 50.9 12.2 1.8e-13 50.5 12.2 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EMC93629.1 - 0.0073 16.1 5.9 0.012 15.4 5.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Pkinase PF00069.25 EMC93631.1 - 2.4e-09 37.0 0.0 2.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC93631.1 - 1.1e-08 34.7 0.0 1.2e-07 31.3 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase VCX_VCY PF15231.6 EMC93631.1 - 0.08 13.6 3.8 0.11 13.2 0.1 2.6 2 0 0 2 2 2 0 Variable charge X/Y family APH PF01636.23 EMC93631.1 - 0.22 11.4 3.1 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PHD PF00628.29 EMC93632.1 - 5e-08 32.7 5.1 1e-07 31.7 5.1 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 EMC93632.1 - 4.1e-06 27.3 0.2 1.4e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 SET domain COesterase PF00135.28 EMC93634.1 - 1.1e-83 281.9 0.2 1.9e-83 281.1 0.2 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC93634.1 - 1.8e-09 37.8 1.3 1.4e-08 34.8 1.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC93634.1 - 0.0016 17.9 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF5020 PF16412.5 EMC93634.1 - 0.033 14.0 0.1 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5020) Collagen PF01391.18 EMC93634.1 - 0.45 10.3 8.1 0.26 11.0 4.2 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) PilJ PF13675.6 EMC93635.1 - 0.025 14.6 1.0 0.088 12.8 1.0 1.9 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf_C2H2_ZHX PF18387.1 EMC93637.1 - 0.013 15.2 2.5 0.52 10.0 0.0 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 EMC93637.1 - 0.093 13.0 3.1 0.26 11.6 3.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 EMC93637.1 - 0.13 12.7 0.3 0.13 12.7 0.3 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type TIM21 PF08294.11 EMC93639.1 - 1.4e-40 138.5 0.0 1.7e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EMC93639.1 - 2.3e-05 24.1 0.0 0.00021 21.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Cas_VVA1548 PF09652.10 EMC93639.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) HET PF06985.11 EMC93640.1 - 1.8e-35 122.4 1.1 2.8e-35 121.8 1.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PMC2NT PF08066.12 EMC93641.1 - 0.0086 16.7 1.2 0.036 14.7 1.2 2.1 1 0 0 1 1 1 1 PMC2NT (NUC016) domain DASH_Dad2 PF08654.10 EMC93641.1 - 6.6 7.2 0.0 6.6 7.2 0.0 4.6 6 0 0 6 6 6 0 DASH complex subunit Dad2 adh_short_C2 PF13561.6 EMC93642.1 - 2.8e-58 197.3 0.4 3.5e-58 196.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC93642.1 - 1.9e-47 161.3 0.4 2.6e-47 160.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC93642.1 - 3.5e-13 49.8 0.4 3.5e-13 49.8 0.4 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMC93642.1 - 0.0014 18.1 0.3 0.002 17.6 0.3 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC93642.1 - 0.0032 16.7 0.2 0.0048 16.1 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 EMC93642.1 - 0.072 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TAP42 PF04177.12 EMC93642.1 - 0.092 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family GDP_Man_Dehyd PF16363.5 EMC93642.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Rad4 PF03835.15 EMC93643.1 - 2.5e-34 118.1 3.2 5e-34 117.1 0.1 2.7 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EMC93643.1 - 3.5e-28 97.8 0.0 9.1e-28 96.5 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 EMC93643.1 - 8.2e-16 58.7 0.3 8.2e-16 58.7 0.3 4.9 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 EMC93643.1 - 2.4e-15 56.1 0.1 5.2e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 EMC93643.1 - 0.00014 22.3 0.2 0.00099 19.5 0.0 2.6 2 1 1 3 3 3 1 Transglutaminase-like superfamily TPP_enzyme_N PF02776.18 EMC93644.1 - 5.6e-23 81.4 0.2 9.1e-23 80.7 0.2 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain GalP_UDP_transf PF01087.22 EMC93646.1 - 1.8e-67 227.4 0.3 7.2e-66 222.1 0.2 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EMC93646.1 - 6.5e-57 191.9 0.0 1.6e-56 190.7 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 EMC93646.1 - 0.0018 17.2 0.0 0.093 11.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4921) Filament PF00038.21 EMC93646.1 - 0.05 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein WG_beta_rep PF14903.6 EMC93646.1 - 0.07 13.4 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 WG containing repeat Oxidored_molyb PF00174.19 EMC93647.1 - 0.053 13.1 0.1 0.4 10.3 0.0 1.9 1 1 1 2 2 2 0 Oxidoreductase molybdopterin binding domain F-box-like PF12937.7 EMC93650.1 - 0.0053 16.6 0.9 0.066 13.1 0.0 2.8 3 0 0 3 3 3 1 F-box-like Methyltransf_25 PF13649.6 EMC93651.1 - 5.1e-16 59.2 0.0 1.5e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC93651.1 - 6.1e-13 49.2 0.0 1.2e-12 48.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC93651.1 - 4.5e-12 46.1 0.0 6.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC93651.1 - 1.9e-11 44.6 0.3 9.8e-11 42.3 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC93651.1 - 3.3e-09 36.7 0.0 4.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC93651.1 - 6.8e-06 25.6 0.0 9e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMC93651.1 - 4.1e-05 23.0 0.0 4.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EMC93651.1 - 0.00017 21.2 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 EMC93651.1 - 0.002 17.6 0.0 1.7 8.1 0.0 2.1 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltr_RsmB-F PF01189.17 EMC93651.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Glyco_transf_34 PF05637.12 EMC93652.1 - 4.4e-63 213.2 0.0 1.4e-62 211.5 0.0 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family OppC_N PF12911.7 EMC93652.1 - 0.75 9.8 2.6 0.76 9.8 0.1 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C F-box-like PF12937.7 EMC93653.1 - 0.0012 18.7 0.1 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like DRMBL PF07522.14 EMC93654.1 - 2.6e-33 114.5 0.0 4.9e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EMC93654.1 - 8.1e-07 28.8 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMC93654.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Pirin PF02678.16 EMC93656.1 - 1.3e-29 102.3 0.1 2.7e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EMC93656.1 - 1.2e-20 73.8 0.0 2.3e-19 69.7 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EMC93656.1 - 1.1e-05 25.1 0.4 0.00016 21.3 0.5 2.3 2 0 0 2 2 2 1 Cupin domain Abhydrolase_1 PF00561.20 EMC93657.1 - 2.7e-17 63.3 0.0 1.7e-14 54.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC93657.1 - 3.4e-12 47.5 0.0 7.9e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC93657.1 - 6.7e-12 45.2 0.0 1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EMC93657.1 - 2.2e-05 24.3 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase EthD PF07110.11 EMC93657.1 - 5.9e-05 24.1 0.1 0.15 13.2 0.0 2.7 2 0 0 2 2 2 2 EthD domain Ndr PF03096.14 EMC93657.1 - 0.0016 17.2 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Methyltransf_23 PF13489.6 EMC93659.1 - 2.3e-25 89.4 0.0 3.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC93659.1 - 1.1e-11 44.7 0.0 6.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EMC93659.1 - 4.8e-11 43.2 0.0 1.3e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC93659.1 - 5e-10 39.9 0.0 9.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC93659.1 - 4.6e-07 30.5 0.0 2.2e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EMC93659.1 - 5.8e-06 25.8 0.0 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Ubie_methyltran PF01209.18 EMC93659.1 - 1.7e-05 24.3 0.0 0.00014 21.3 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMC93659.1 - 0.00035 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EMC93659.1 - 0.0029 17.1 0.0 0.0094 15.4 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EMC93659.1 - 0.003 17.1 0.0 0.013 15.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 EMC93659.1 - 0.004 16.7 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 EMC93659.1 - 0.034 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 EMC93659.1 - 0.057 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Mu-like_Com PF10122.9 EMC93663.1 - 0.021 14.2 1.1 0.036 13.5 1.1 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com DUF35_N PF12172.8 EMC93663.1 - 0.046 13.6 2.6 2.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-NADH-PPase PF09297.11 EMC93663.1 - 0.16 11.6 3.7 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain YhfH PF14149.6 EMC93663.1 - 0.16 11.9 0.5 0.16 11.9 0.5 2.0 2 0 0 2 2 2 0 YhfH-like protein zf-TFIIB PF13453.6 EMC93663.1 - 0.19 11.1 2.0 8.3 5.8 0.4 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-ribbon_3 PF13248.6 EMC93663.1 - 0.24 10.9 5.2 0.88 9.1 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 EMC93663.1 - 0.27 11.4 6.1 0.88 9.7 0.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 EMC93663.1 - 0.52 10.1 4.9 0.77 9.6 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf_CopZ PF18423.1 EMC93663.1 - 0.61 10.1 2.7 8.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Zinc binding domain zf-FPG_IleRS PF06827.14 EMC93663.1 - 3 7.8 7.8 2.6 8.0 0.6 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-tcix PF14952.6 EMC93663.1 - 3.7 7.3 8.7 0.52 10.0 1.4 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding bZIP_1 PF00170.21 EMC93664.1 - 4.9e-05 23.3 9.7 0.00011 22.2 9.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 EMC93664.1 - 0.00046 20.0 1.3 0.13 12.0 1.2 2.1 2 0 0 2 2 2 2 Transcription factor PAP1 bZIP_2 PF07716.15 EMC93664.1 - 0.19 11.8 9.9 0.19 11.8 8.3 1.8 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 EMC93664.1 - 1.9 9.0 9.7 3.5 8.2 9.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Fungal_trans PF04082.18 EMC93665.1 - 1.4e-12 47.2 0.1 2.3e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93665.1 - 4.5e-06 26.7 10.6 7.9e-06 25.9 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 EMC93665.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF3654 PF12376.8 EMC93665.1 - 0.26 11.5 4.2 0.069 13.3 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) FAD_binding_3 PF01494.19 EMC93667.1 - 1.9e-18 66.9 0.1 1.4e-17 64.0 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC93667.1 - 5.7e-10 38.9 0.3 9.7e-05 21.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC93667.1 - 6.7e-07 29.5 0.3 1.6e-06 28.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC93667.1 - 1e-06 29.2 0.4 9.9e-05 22.8 0.2 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC93667.1 - 1.2e-06 28.4 0.3 0.00019 21.2 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMC93667.1 - 3.7e-06 26.3 0.2 8.9e-06 25.0 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMC93667.1 - 1.7e-05 23.7 0.1 0.014 14.1 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 EMC93667.1 - 0.00033 19.9 0.0 0.00054 19.1 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EMC93667.1 - 0.034 13.2 0.3 2.3 7.2 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMC93667.1 - 0.056 13.4 0.8 3.9 7.4 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EMC93667.1 - 0.074 12.4 1.7 0.15 11.4 1.7 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMC93667.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EMC93667.1 - 0.099 11.9 0.0 0.54 9.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EMC93667.1 - 0.2 11.3 0.3 0.53 9.9 0.3 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAM76 PF16046.5 EMC93668.1 - 0.0014 18.1 2.2 0.0016 17.8 2.2 1.1 1 0 0 1 1 1 1 FAM76 protein Glyco_hydro_43 PF04616.14 EMC93669.1 - 5.6e-28 98.1 4.4 8e-27 94.3 4.4 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.16 EMC93670.1 - 1.3e-42 146.0 41.4 7.9e-42 143.4 40.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF5337 PF17272.2 EMC93670.1 - 0.11 12.3 0.9 0.46 10.3 0.9 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Cu-oxidase_2 PF07731.14 EMC93672.1 - 6.2e-49 165.2 9.6 1.4e-44 151.1 0.2 4.9 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMC93672.1 - 7.7e-48 161.4 6.6 1.9e-44 150.5 1.0 4.3 4 0 0 4 4 4 2 Multicopper oxidase CBM_20 PF00686.19 EMC93672.1 - 3.9e-35 119.6 0.2 2.1e-29 101.2 0.0 2.9 1 1 1 2 2 2 2 Starch binding domain Cu-oxidase PF00394.22 EMC93672.1 - 6.6e-35 120.6 0.1 2.4e-34 118.8 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Na_Ca_ex PF01699.24 EMC93673.1 - 9.6e-29 100.3 26.4 1.4e-15 57.5 8.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2157 PF09925.9 EMC93673.1 - 0.013 15.3 8.3 0.026 14.3 0.8 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.6 EMC93673.1 - 0.022 14.4 6.5 2.2 7.9 5.2 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1298 PF06974.13 EMC93673.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) DUF5337 PF17272.2 EMC93673.1 - 0.15 11.9 0.4 6.5 6.7 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5337) MaAIMP_sms PF16951.5 EMC93673.1 - 0.19 11.5 5.0 7.6 6.4 0.3 2.9 2 0 0 2 2 2 0 Putative methionine and alanine importer, small subunit TMEM252 PF15664.5 EMC93673.1 - 0.39 10.4 2.2 1.6 8.5 0.3 2.6 3 0 0 3 3 3 0 Transmembrane protein 252 family TspO_MBR PF03073.15 EMC93674.1 - 4.9e-47 159.4 4.4 6e-47 159.1 4.4 1.1 1 0 0 1 1 1 1 TspO/MBR family Corona_NS3b PF03053.14 EMC93674.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 ORF3b coronavirus protein DUF3546 PF12066.8 EMC93675.1 - 4.7e-31 107.2 1.7 1.5e-30 105.6 1.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EMC93675.1 - 1.4e-12 47.2 0.4 3.4e-12 45.9 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EMC93675.1 - 2e-11 44.7 7.4 2e-11 44.7 7.4 2.5 2 1 0 2 2 2 1 Arsenite-resistance protein 2 Beta-lactamase PF00144.24 EMC93676.1 - 7.6e-29 101.0 0.1 1.3e-28 100.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase ABC_tran PF00005.27 EMC93677.1 - 2.3e-27 96.2 0.0 1.5e-26 93.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EMC93677.1 - 0.002 18.0 0.1 0.0037 17.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EMC93677.1 - 0.0056 16.5 0.1 0.11 12.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EMC93677.1 - 0.0083 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 EMC93677.1 - 0.011 14.9 12.3 0.019 14.1 12.3 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein SbcCD_C PF13558.6 EMC93677.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 EMC93677.1 - 0.23 10.4 0.4 0.47 9.4 0.4 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FAD_binding_2 PF00890.24 EMC93678.1 - 7.4e-125 417.3 2.3 9.8e-125 416.9 2.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EMC93678.1 - 2.3e-45 153.7 3.0 3.4e-45 153.2 3.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EMC93678.1 - 4.1e-05 23.0 1.0 0.031 13.5 0.4 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC93678.1 - 6.2e-05 22.4 0.2 0.018 14.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EMC93678.1 - 6.7e-05 22.1 1.5 0.084 11.9 1.9 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EMC93678.1 - 0.0097 15.2 0.6 0.016 14.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EMC93678.1 - 0.074 12.3 0.1 4.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC93678.1 - 0.078 12.6 1.6 0.28 10.7 1.6 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC93678.1 - 0.12 11.0 0.0 0.47 9.1 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein Methyltransf_2 PF00891.18 EMC93682.1 - 4e-19 68.7 0.0 5.7e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HTH_29 PF13551.6 EMC93682.1 - 0.094 12.8 0.6 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix MFS_1 PF07690.16 EMC93683.1 - 5.3e-23 81.5 21.3 5.3e-23 81.5 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC93683.1 - 9.5e-06 24.3 3.7 1.4e-05 23.7 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-RING_2 PF13639.6 EMC93686.1 - 6.2e-12 45.7 12.4 8.1e-12 45.3 12.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EMC93686.1 - 3.8e-10 39.9 7.6 6e-10 39.3 7.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EMC93686.1 - 2.5e-07 30.4 11.8 3.7e-07 29.9 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC93686.1 - 2.3e-06 27.4 11.5 3.2e-06 26.9 11.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EMC93686.1 - 1.2e-05 24.8 8.2 1.8e-05 24.3 8.2 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EMC93686.1 - 1.8e-05 24.4 10.4 3.1e-05 23.6 10.4 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EMC93686.1 - 6.9e-05 22.8 5.7 0.00012 22.1 5.7 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EMC93686.1 - 6.9e-05 22.8 5.8 0.00018 21.4 6.2 1.5 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EMC93686.1 - 0.00031 20.6 7.5 0.0005 19.9 7.5 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EMC93686.1 - 0.00091 19.1 10.4 0.0013 18.6 10.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EMC93686.1 - 0.0028 17.5 9.3 0.0044 16.9 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 EMC93686.1 - 0.016 15.0 4.3 0.027 14.3 4.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 EMC93686.1 - 0.12 12.5 5.9 0.13 12.3 4.3 1.9 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 EMC93686.1 - 0.13 12.4 12.3 0.21 11.8 12.3 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EMC93686.1 - 0.34 10.7 10.3 20 5.1 10.3 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 EMC93686.1 - 0.5 10.3 5.3 0.31 11.0 3.2 1.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EMC93686.1 - 0.84 10.0 11.4 1.9 8.9 11.4 1.6 1 1 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 EMC93686.1 - 1 9.6 10.4 3.1 8.0 10.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RNA_pol_I_TF PF04090.12 EMC93688.1 - 3.3e-15 56.1 0.0 8.1e-14 51.6 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_6 PF13174.6 EMC93688.1 - 0.13 13.0 6.6 1.5 9.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMC93688.1 - 5.2 7.4 7.9 1.4e+02 3.0 1.7 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DPBB_1 PF03330.18 EMC93689.1 - 9.8e-07 29.0 0.1 1.5e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase CDC73_C PF05179.14 EMC93692.1 - 5.5e-53 178.9 0.0 9.1e-53 178.2 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal E1-E2_ATPase PF00122.20 EMC93693.1 - 2.8e-33 115.0 0.9 2.8e-33 115.0 0.9 4.4 4 2 1 5 5 5 2 E1-E2 ATPase Hydrolase PF00702.26 EMC93693.1 - 4.8e-17 63.0 0.0 1.2e-16 61.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMC93693.1 - 8.3e-13 47.8 0.0 2.4e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMC93693.1 - 0.0015 18.3 0.1 0.0036 17.1 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMC93693.1 - 0.0056 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) p450 PF00067.22 EMC93694.1 - 3.7e-72 243.5 0.0 4.6e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 EMC93695.1 - 1.6e-54 185.4 45.5 2.1e-54 185.0 45.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC93695.1 - 2.9e-29 102.0 33.1 2.9e-29 102.0 33.1 2.0 2 0 0 2 2 2 1 Amino acid permease DUF1774 PF08611.10 EMC93695.1 - 0.55 10.6 0.0 0.55 10.6 0.0 3.7 4 0 0 4 4 4 0 Fungal protein of unknown function (DUF1774) Amidohydro_1 PF01979.20 EMC93696.1 - 2.7e-23 82.8 0.9 1.5e-22 80.4 0.9 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMC93696.1 - 1.6e-14 54.3 0.3 1.4e-09 38.0 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 EMC93697.1 - 2.1e-32 113.1 0.4 1.4e-31 110.4 0.4 1.9 1 1 0 1 1 1 1 Amidohydrolase Fe-ADH PF00465.19 EMC93698.1 - 1.1e-65 221.9 0.0 1.4e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMC93698.1 - 2.3e-11 43.9 0.0 3.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PFK PF00365.20 EMC93698.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosphofructokinase TMIE PF16038.5 EMC93699.1 - 0.18 11.7 0.4 0.18 11.7 0.4 2.1 2 0 0 2 2 2 0 TMIE protein MARVEL PF01284.23 EMC93699.1 - 0.25 11.3 9.8 0.36 10.9 9.4 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF962 PF06127.11 EMC93699.1 - 0.33 11.1 5.1 0.078 13.1 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF3021 PF11457.8 EMC93699.1 - 5.2 7.4 13.9 45 4.4 13.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) PAN_1 PF00024.26 EMC93701.1 - 0.015 15.2 0.2 0.02 14.8 0.2 1.3 1 0 0 1 1 1 0 PAN domain Brix PF04427.18 EMC93704.1 - 1.4e-35 123.2 0.1 1.9e-35 122.8 0.1 1.2 1 0 0 1 1 1 1 Brix domain Glutaredoxin PF00462.24 EMC93705.1 - 2.2e-20 72.6 0.0 1.1e-18 67.2 0.0 2.6 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EMC93705.1 - 1.6e-13 50.5 0.0 3.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EMC93705.1 - 0.0025 18.1 0.0 0.13 12.6 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 EMC93705.1 - 0.0085 15.5 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family CDC27 PF09507.10 EMC93705.1 - 0.082 12.3 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MAPEG PF01124.18 EMC93706.1 - 1.8e-15 57.0 0.6 2.3e-15 56.6 0.6 1.1 1 0 0 1 1 1 1 MAPEG family DUF1304 PF06993.12 EMC93706.1 - 0.0099 15.9 0.2 0.016 15.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) CoA_binding_2 PF13380.6 EMC93707.1 - 1.3e-25 90.1 0.0 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain HIT PF01230.23 EMC93708.1 - 8.6e-23 80.9 0.3 1.1e-22 80.5 0.3 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EMC93708.1 - 0.00035 21.0 0.1 0.00049 20.5 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EMC93708.1 - 0.021 14.7 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 EMC93708.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain EF-hand_7 PF13499.6 EMC93710.1 - 6.7e-11 42.5 0.4 9e-06 26.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EMC93710.1 - 5.9e-09 35.1 1.9 9.9e-05 22.0 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 EMC93710.1 - 7.9e-09 35.7 0.0 0.00076 19.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EMC93710.1 - 9.9e-08 31.0 1.5 0.0018 17.7 0.1 3.4 3 1 1 4 4 4 2 EF hand EF-hand_8 PF13833.6 EMC93710.1 - 1.4e-06 28.0 0.3 3.5e-05 23.5 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 EMC93710.1 - 0.065 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) zf-AN1 PF01428.16 EMC93711.1 - 1.3e-22 79.7 24.5 1.8e-11 44.0 6.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EMC93711.1 - 0.027 14.7 5.5 0.027 14.7 5.5 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EMC93711.1 - 0.26 11.6 13.0 1.8 9.0 1.1 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain AFG1_ATPase PF03969.16 EMC93714.1 - 3.4e-94 315.7 0.1 4e-89 299.0 0.0 2.3 2 1 0 2 2 2 2 AFG1-like ATPase AAA_14 PF13173.6 EMC93714.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC93714.1 - 0.0012 19.2 0.0 1.7 9.0 0.0 2.9 2 1 0 3 3 3 2 AAA ATPase domain Bac_DnaA PF00308.18 EMC93714.1 - 0.0023 17.8 0.1 1 9.2 0.3 2.6 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 EMC93714.1 - 0.0042 17.4 0.0 0.019 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EMC93714.1 - 0.011 16.1 0.2 0.041 14.3 0.1 2.1 2 1 0 2 2 2 0 RNA helicase VASP_tetra PF08776.11 EMC93714.1 - 0.042 13.4 0.3 0.11 12.0 0.3 1.7 1 0 0 1 1 1 0 VASP tetramerisation domain TsaE PF02367.17 EMC93714.1 - 0.045 13.7 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EMC93714.1 - 0.052 13.5 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 EMC93714.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 EMC93714.1 - 0.11 12.9 0.1 0.51 10.8 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NMT1 PF09084.11 EMC93716.1 - 1.2e-76 257.5 0.0 1.6e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EMC93716.1 - 0.00013 21.8 0.0 1.7 8.2 0.0 3.6 3 1 1 4 4 4 2 NMT1-like family FMN_red PF03358.15 EMC93716.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase NAD_binding_2 PF03446.15 EMC93717.1 - 2.5e-32 112.2 0.1 3.4e-32 111.8 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMC93717.1 - 4.5e-27 94.7 0.0 8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EMC93717.1 - 2.3e-06 28.1 0.0 4.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EMC93717.1 - 2.9e-05 23.5 0.0 4.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EMC93717.1 - 0.0072 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EMC93717.1 - 0.019 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EMC93717.1 - 0.035 13.9 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.18 EMC93717.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF3237 PF11578.8 EMC93718.1 - 3.1e-34 118.0 0.0 3.7e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) SYF2 PF08231.12 EMC93719.1 - 2.3e-48 164.6 8.8 2.3e-48 164.6 8.8 2.0 2 0 0 2 2 2 1 SYF2 splicing factor GMC_oxred_C PF05199.13 EMC93719.1 - 0.78 10.3 3.2 7.5 7.1 3.2 2.3 1 1 0 1 1 1 0 GMC oxidoreductase SMC_N PF02463.19 EMC93720.1 - 2.3e-62 210.3 13.1 2.3e-61 207.0 13.1 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMC93720.1 - 3.8e-26 91.7 0.2 2.8e-25 88.9 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EMC93720.1 - 7.2e-14 52.3 14.0 1.4e-07 31.6 0.0 4.4 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMC93720.1 - 8.3e-12 45.5 45.3 1e-09 38.6 19.9 4.7 2 2 0 2 2 2 2 AAA ATPase domain APG6_N PF17675.1 EMC93720.1 - 0.00016 22.2 137.7 0.13 12.8 13.7 8.4 3 2 5 8 8 8 4 Apg6 coiled-coil region AAA_23 PF13476.6 EMC93720.1 - 0.00056 20.5 56.4 0.00056 20.5 56.4 7.1 2 2 0 2 2 1 1 AAA domain Spc7 PF08317.11 EMC93720.1 - 0.00083 18.3 117.0 0.011 14.6 12.9 6.8 2 2 5 7 7 7 6 Spc7 kinetochore protein AAA_29 PF13555.6 EMC93720.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.9 EMC93720.1 - 0.0065 16.7 0.9 0.0065 16.7 0.9 9.8 8 3 2 10 10 10 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fic_N PF13784.6 EMC93720.1 - 0.0076 16.3 3.8 5.6 7.1 1.9 3.7 2 0 0 2 2 2 2 Fic/DOC family N-terminal PCI PF01399.27 EMC93720.1 - 0.21 12.1 3.7 1.1 9.8 0.2 3.4 3 0 0 3 3 3 0 PCI domain DUF87 PF01935.17 EMC93720.1 - 2.6 8.1 0.0 2.6 8.1 0.0 6.7 3 2 2 5 5 2 0 Helicase HerA, central domain Abhydrolase_1 PF00561.20 EMC93722.1 - 4.6e-16 59.2 1.0 1.2e-15 57.9 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC93722.1 - 8.5e-14 52.7 5.5 2.5e-12 47.9 5.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC93722.1 - 1.9e-09 37.2 0.0 7.8e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EMC93722.1 - 0.02 14.5 0.1 0.039 13.6 0.0 1.5 2 0 0 2 2 2 0 Putative esterase AXE1 PF05448.12 EMC93722.1 - 0.022 13.5 0.1 0.033 12.8 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 EMC93722.1 - 0.05 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Beach PF02138.18 EMC93723.1 - 4e-118 393.8 0.0 6.7e-118 393.0 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 EMC93723.1 - 7.8e-10 39.1 0.0 1.8e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 EMC93723.1 - 4.7e-09 36.3 0.0 1.3e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EMC93723.1 - 0.0053 17.6 0.5 0.58 11.1 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4704 PF15787.5 EMC93723.1 - 0.022 14.0 0.0 0.051 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) Peptidase_S8 PF00082.22 EMC93724.1 - 1.1e-34 120.1 8.9 1.5e-34 119.6 8.4 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EMC93724.1 - 1.6e-20 73.5 0.5 4e-20 72.3 0.5 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Phasin PF05597.11 EMC93724.1 - 0.069 13.1 1.4 0.084 12.9 0.2 1.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Acyltransferase PF01553.21 EMC93725.1 - 1.2e-31 109.2 0.0 2.1e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Poly_export PF02563.16 EMC93725.1 - 0.044 14.0 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein Tmemb_170 PF10190.9 EMC93725.1 - 0.053 13.9 1.7 0.14 12.5 1.7 1.6 1 0 0 1 1 1 0 Putative transmembrane protein 170 adh_short PF00106.25 EMC93726.1 - 1.1e-40 139.1 0.6 6.8e-40 136.6 0.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93726.1 - 9.1e-31 107.2 0.6 1.9e-29 102.9 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC93726.1 - 7.1e-10 39.1 0.1 1.5e-09 38.0 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC93726.1 - 0.00072 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC93726.1 - 0.029 14.3 0.5 1 9.2 0.4 2.3 1 1 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMC93726.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EMC93726.1 - 0.16 11.5 0.2 0.29 10.7 0.2 1.5 1 1 0 1 1 1 0 NmrA-like family LDcluster4 PF18306.1 EMC93726.1 - 0.2 11.2 2.0 7.3 6.2 0.1 2.3 2 0 0 2 2 2 0 SLOG cluster4 family Ribonuclease PF00545.20 EMC93727.1 - 3e-07 31.1 0.2 4.8e-07 30.4 0.2 1.4 1 1 0 1 1 1 1 ribonuclease DUF5442 PF17514.2 EMC93727.1 - 0.064 13.5 0.8 0.095 12.9 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5442) TAL_FSA PF00923.19 EMC93729.1 - 2.5e-94 315.9 2.3 2.8e-94 315.7 2.3 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 EMC93729.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Sod_Cu PF00080.20 EMC93730.1 - 1.5e-46 158.1 7.0 1.7e-46 157.9 7.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) adh_short PF00106.25 EMC93731.1 - 1.5e-29 102.9 0.0 2.3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93731.1 - 1.2e-22 80.6 0.0 1.6e-21 77.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RPEL PF02755.15 EMC93731.1 - 0.15 11.8 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 RPEL repeat Ras PF00071.22 EMC93732.1 - 9.9e-53 178.0 0.0 1.2e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC93732.1 - 4e-21 75.4 0.0 5.9e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC93732.1 - 9.2e-07 28.5 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMC93732.1 - 2.1e-05 24.2 0.1 0.00099 18.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMC93732.1 - 5.8e-05 23.1 0.0 8.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMC93732.1 - 0.0046 16.9 0.2 2.2 8.1 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EMC93732.1 - 0.025 14.0 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EMC93732.1 - 0.046 14.0 0.1 0.48 10.7 0.2 2.4 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EMC93732.1 - 0.054 12.7 0.2 0.38 9.9 0.1 1.9 1 1 1 2 2 2 0 NB-ARC domain DUF87 PF01935.17 EMC93732.1 - 0.073 13.2 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain PliI PF16743.5 EMC93732.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Periplasmic lysozyme inhibitor of I-type lysozyme EMC1_C PF07774.13 EMC93733.1 - 2.3e-73 246.4 0.0 4e-73 245.6 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EMC93733.1 - 1.3e-27 96.9 10.5 4.7e-25 88.6 3.5 2.6 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 EMC93733.1 - 8.8e-07 28.6 0.7 0.31 11.0 0.0 5.4 5 0 0 5 5 5 2 PQQ enzyme repeat adh_short_C2 PF13561.6 EMC93734.1 - 7.2e-33 114.1 0.0 9e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC93734.1 - 1.3e-28 99.8 0.0 3e-28 98.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMC93734.1 - 8.4e-06 25.8 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EMC93734.1 - 0.0052 16.5 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 EMC93734.1 - 0.0053 16.1 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EMC93734.1 - 0.015 15.4 0.0 0.036 14.1 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Catalase-rel PF06628.12 EMC93734.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Catalase-related immune-responsive Epimerase PF01370.21 EMC93734.1 - 0.03 13.8 0.0 0.094 12.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EMC93734.1 - 0.037 13.9 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tir_receptor_C PF07489.11 EMC93734.1 - 0.056 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus AdoHcyase_NAD PF00670.21 EMC93734.1 - 0.068 13.2 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 EMC93734.1 - 0.1 13.1 0.0 0.21 12.0 0.0 1.5 2 0 0 2 2 2 0 Putative NAD(P)-binding SNase PF00565.17 EMC93735.1 - 1.6e-78 260.1 0.0 3.1e-26 92.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EMC93735.1 - 4.4e-20 71.9 0.0 1e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EMC93735.1 - 5e-07 29.3 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 EMC93735.1 - 0.074 13.5 0.1 0.23 12.0 0.1 1.9 1 0 0 1 1 1 0 Agenet domain RIO1 PF01163.22 EMC93736.1 - 5.7e-71 238.0 0.1 5.7e-71 238.0 0.1 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EMC93736.1 - 0.039 13.9 8.1 0.14 12.0 0.1 3.4 3 2 1 4 4 4 0 Phosphotransferase enzyme family Kdo PF06293.14 EMC93736.1 - 0.1 11.9 3.7 0.98 8.7 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 EMC93739.1 - 2.7e-15 55.9 0.1 1.5e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EMC93740.1 - 1.1e-25 89.4 13.1 1.4e-07 32.0 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC93740.1 - 1.8e-06 28.2 0.0 0.44 10.9 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMC93740.1 - 7e-05 21.9 0.1 0.06 12.3 0.0 3.1 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EMC93740.1 - 0.00047 18.9 0.0 0.053 12.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 EMC93740.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DUF3591 PF12157.8 EMC93740.1 - 0.25 10.0 0.0 0.37 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) NUDE_C PF04880.13 EMC93741.1 - 1.5e-43 149.4 5.9 1.5e-43 149.4 5.9 3.8 3 1 1 4 4 4 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 EMC93741.1 - 0.011 16.2 7.0 0.011 16.2 7.0 4.4 2 1 2 4 4 4 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 EMC93741.1 - 0.27 11.4 36.1 0.2 11.8 25.1 3.7 2 1 1 3 3 3 0 Tropomyosin like FTCD_C PF04961.12 EMC93741.1 - 1 9.1 5.3 1.9 8.2 5.3 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase LPP PF04728.13 EMC93741.1 - 1.8 9.0 6.2 2.3 8.7 0.3 3.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper ERM PF00769.19 EMC93741.1 - 2.2 8.1 37.7 0.77 9.5 32.5 2.3 2 1 0 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 EMC93741.1 - 2.8 8.0 32.1 3 7.9 26.0 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.9 EMC93741.1 - 3.7 6.0 16.9 7 5.1 16.9 1.4 1 0 0 1 1 1 0 Macoilin family Histone_HNS PF00816.21 EMC93741.1 - 4.2 8.2 17.4 14 6.6 0.2 3.4 2 1 0 2 2 2 0 H-NS histone family DUF1043 PF06295.12 EMC93741.1 - 6.9 6.7 8.7 14 5.7 8.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) ACC_central PF08326.12 EMC93743.1 - 2.4e-276 918.7 0.0 3e-276 918.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EMC93743.1 - 3.4e-187 623.0 0.0 5.2e-187 622.4 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EMC93743.1 - 7.6e-53 179.1 0.0 1.5e-52 178.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EMC93743.1 - 7.3e-28 97.3 0.1 1.7e-27 96.1 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EMC93743.1 - 2.1e-23 82.5 0.0 6.4e-21 74.5 0.0 3.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EMC93743.1 - 9.2e-17 60.6 0.1 2.6e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EMC93743.1 - 0.0002 21.0 0.0 0.00057 19.5 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EMC93743.1 - 0.00028 21.0 0.0 0.001 19.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 EMC93743.1 - 0.0038 16.8 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EMC93743.1 - 0.0054 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like GxGYxYP_N PF16216.5 EMC93743.1 - 0.0099 16.1 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Bot1p PF12298.8 EMC93745.1 - 3.9e-46 157.3 1.4 3.9e-46 157.3 1.4 1.7 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Nitroreductase PF00881.24 EMC93747.1 - 8.1e-14 52.0 0.0 9.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF4804 PF16062.5 EMC93748.1 - 3.4e-91 306.3 0.0 9.1e-58 196.1 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4804) Synapsin_N PF10581.9 EMC93749.1 - 0.0045 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Synapsin N-terminal 2OG-FeII_Oxy PF03171.20 EMC93749.1 - 0.017 15.6 0.0 0.057 13.9 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EMC93750.1 - 4.1e-30 104.9 36.0 1.3e-29 103.2 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMC93750.1 - 8.5e-05 22.0 6.9 0.00021 20.7 6.9 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB F-box-like PF12937.7 EMC93751.1 - 0.00051 19.9 1.5 0.0016 18.3 1.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC93751.1 - 0.0091 15.9 2.0 0.035 14.0 2.0 2.0 1 0 0 1 1 1 1 F-box domain Glyco_hydro_62 PF03664.13 EMC93752.1 - 1.2e-148 493.8 16.0 1.4e-148 493.6 16.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 ParA PF10609.9 EMC93754.1 - 1.7e-90 302.8 0.0 8.8e-63 212.0 0.0 2.0 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EMC93754.1 - 9.9e-13 48.3 0.0 9.2e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EMC93754.1 - 1.5e-06 27.7 0.0 7.8e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 EMC93754.1 - 5.6e-06 25.7 0.2 0.00041 19.6 0.3 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EMC93754.1 - 6.6e-05 22.9 0.1 0.0022 17.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 EMC93754.1 - 0.00017 21.5 1.2 0.033 14.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EMC93754.1 - 0.013 15.1 0.9 0.022 14.3 0.3 1.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EMC93754.1 - 0.015 14.3 0.3 0.025 13.6 0.3 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 EMC93754.1 - 0.054 13.0 0.2 0.3 10.6 0.2 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 EMC93754.1 - 0.098 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 EMC93754.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EMC93754.1 - 0.14 12.5 0.5 0.3 11.4 0.2 1.7 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EMC93754.1 - 0.16 11.8 1.0 0.53 10.2 0.9 1.7 2 0 0 2 2 2 0 RsgA GTPase PQ-loop PF04193.14 EMC93755.1 - 1.5e-39 133.5 11.3 6.8e-21 73.8 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat Ni_hydr_CYTB PF01292.20 EMC93755.1 - 0.058 13.0 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 AcrZ PF10766.9 EMC93755.1 - 0.14 11.7 0.4 0.38 10.3 0.4 1.7 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Ank_2 PF12796.7 EMC93756.1 - 6.1e-22 78.0 0.4 1e-11 45.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC93756.1 - 1.3e-13 51.2 1.4 2.2e-07 31.3 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMC93756.1 - 3.6e-11 43.1 0.5 1.4e-08 34.8 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EMC93756.1 - 2.8e-10 40.2 0.1 2e-07 31.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EMC93756.1 - 1.5e-09 37.3 0.2 6.3e-06 26.1 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat GST_N_3 PF13417.6 EMC93758.1 - 1.2e-18 67.2 0.0 1.8e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMC93758.1 - 6e-15 55.3 0.1 8.9e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMC93758.1 - 5.8e-07 29.8 0.2 1.2e-06 28.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EMC93758.1 - 0.015 16.0 0.0 0.024 15.4 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain adh_short_C2 PF13561.6 EMC93765.1 - 2.6e-56 190.8 0.8 8.2e-56 189.2 0.8 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC93765.1 - 5.5e-32 110.8 0.9 1.8e-31 109.1 0.9 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC93765.1 - 2e-07 31.1 1.2 2.9e-06 27.3 1.2 2.1 1 1 0 1 1 1 1 KR domain STALD PF18185.1 EMC93765.1 - 0.06 12.7 3.5 0.12 11.7 1.1 2.3 1 1 0 2 2 2 0 Sir2- and TIR-associating SLOG family F420_oxidored PF03807.17 EMC93765.1 - 0.1 13.2 0.1 0.21 12.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent BTB PF00651.31 EMC93767.1 - 1.2e-08 35.2 0.0 5.1e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain MAT1 PF06391.13 EMC93769.1 - 3.8 7.3 15.6 0.21 11.4 6.7 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 p450 PF00067.22 EMC93770.1 - 4.6e-25 88.3 0.0 6.3e-24 84.5 0.0 2.2 2 1 0 2 2 2 1 Cytochrome P450 CobD_Cbib PF03186.13 EMC93770.1 - 0.097 11.9 0.1 0.5 9.5 0.0 1.9 2 0 0 2 2 2 0 CobD/Cbib protein Proteasome PF00227.26 EMC93771.1 - 2.7e-54 183.6 0.1 3.5e-54 183.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMC93771.1 - 5.3e-13 48.4 0.3 2.1e-12 46.5 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature MAT1-1-2 PF17043.5 EMC93771.1 - 0.041 13.7 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function WD40 PF00400.32 EMC93772.1 - 1e-13 51.5 9.6 3.7e-05 24.4 0.0 7.6 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC93772.1 - 1.1e-09 38.5 0.0 0.013 15.8 0.0 4.5 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMC93772.1 - 5.3e-06 25.6 0.0 0.00046 19.3 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EMC93772.1 - 1e-05 25.3 3.6 0.0013 18.3 1.7 2.4 2 0 0 2 2 2 2 PQQ-like domain CLTH PF10607.9 EMC93772.1 - 0.0019 18.1 0.1 0.0031 17.4 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PQQ PF01011.21 EMC93772.1 - 0.015 15.2 0.0 0.069 13.1 0.0 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat PQQ_3 PF13570.6 EMC93772.1 - 0.65 10.6 9.2 0.53 10.9 0.1 4.2 3 1 1 4 4 4 0 PQQ-like domain PLU-1 PF08429.11 EMC93773.1 - 2e-103 346.1 13.0 1.9e-101 339.7 13.1 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EMC93773.1 - 2.9e-42 143.7 0.2 6.8e-42 142.5 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EMC93773.1 - 2.8e-21 76.0 0.1 7.6e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EMC93773.1 - 1.1e-16 60.5 3.5 2.3e-16 59.4 3.5 1.6 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 EMC93773.1 - 7e-13 48.3 37.6 1.1e-07 31.6 8.7 3.0 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 EMC93773.1 - 2e-12 47.3 10.4 2e-12 47.3 10.4 2.1 2 0 0 2 2 2 1 C5HC2 zinc finger DUF1284 PF06935.11 EMC93773.1 - 0.042 14.3 0.4 0.042 14.3 0.4 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1284) PHD_4 PF16866.5 EMC93773.1 - 1 9.5 21.9 0.19 11.9 5.0 2.8 2 0 0 2 2 2 0 PHD-finger GIY-YIG PF01541.24 EMC93774.1 - 2.8e-12 46.8 0.0 5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 EMC93774.1 - 0.00034 20.7 1.3 0.00061 19.9 1.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 EMC93774.1 - 0.0095 16.2 0.6 0.017 15.4 0.6 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EMC93774.1 - 0.025 14.7 0.7 0.044 13.9 0.7 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.29 EMC93774.1 - 0.03 14.2 2.5 0.058 13.3 2.5 1.5 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 EMC93774.1 - 0.032 14.5 1.1 0.082 13.2 0.3 2.0 2 0 0 2 2 2 0 C1 domain zf-RING-like PF08746.11 EMC93774.1 - 0.12 12.7 4.1 0.44 10.9 4.2 2.1 1 1 0 1 1 1 0 RING-like domain zinc_ribbon_5 PF13719.6 EMC93774.1 - 0.13 12.1 0.4 5.7 6.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_2 PF13639.6 EMC93774.1 - 0.15 12.4 2.7 0.32 11.4 2.7 1.6 1 0 0 1 1 1 0 Ring finger domain MTHFR PF02219.17 EMC93775.1 - 1.7e-98 329.5 0.0 2.7e-98 328.8 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3295 PF11702.8 EMC93775.1 - 0.018 14.4 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Thymidylate_kin PF02223.17 EMC93777.1 - 2.3e-48 164.3 0.0 2.7e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EMC93777.1 - 0.00048 20.4 0.1 0.00078 19.7 0.1 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMC93777.1 - 0.00086 18.8 0.2 0.0091 15.5 0.0 2.2 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EMC93777.1 - 0.012 15.8 0.1 0.035 14.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF463 PF04317.12 EMC93777.1 - 0.015 14.2 0.1 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_17 PF13207.6 EMC93777.1 - 0.021 15.3 0.2 0.39 11.1 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 EMC93777.1 - 0.027 15.0 0.1 0.12 12.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EMC93777.1 - 0.14 12.5 0.0 0.75 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TGT PF01702.18 EMC93778.1 - 9.5e-61 205.9 0.0 1.2e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase FAD-oxidase_C PF02913.19 EMC93781.1 - 2.2e-62 210.9 0.0 3.2e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMC93781.1 - 1.2e-36 125.5 0.5 2.8e-36 124.3 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain TPR_10 PF13374.6 EMC93782.1 - 1.1e-73 241.3 16.0 5.3e-13 48.4 0.1 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 EMC93782.1 - 7.7e-65 215.2 34.4 2.5e-14 53.3 1.6 7.0 2 1 6 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 EMC93782.1 - 2e-15 55.6 14.9 0.00082 19.2 0.0 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMC93782.1 - 2.5e-12 47.2 20.7 0.026 15.2 0.0 8.2 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_4 PF07721.14 EMC93782.1 - 2.6e-12 46.1 23.6 0.045 14.4 0.1 7.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EMC93782.1 - 5.1e-12 45.1 10.4 0.088 12.7 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMC93782.1 - 2.3e-11 42.9 21.0 0.054 13.6 0.1 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMC93782.1 - 2.1e-10 40.9 24.0 0.34 11.5 0.0 8.3 5 4 3 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 EMC93782.1 - 6.3e-06 26.2 13.8 0.98 10.0 0.1 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EMC93782.1 - 1.4e-05 24.9 13.2 0.21 11.9 0.0 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat NB-ARC PF00931.22 EMC93782.1 - 2.1e-05 23.8 0.0 7.5e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 EMC93782.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMC93782.1 - 0.00016 22.0 0.0 0.00051 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC93782.1 - 0.0016 18.9 5.0 0.0038 17.6 1.9 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EMC93782.1 - 0.014 15.0 0.0 0.054 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF3646 PF12362.8 EMC93782.1 - 0.021 15.1 0.4 0.078 13.3 0.4 1.9 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal RPN6_N PF18055.1 EMC93782.1 - 0.11 12.8 4.1 0.93 9.9 0.1 3.2 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_14 PF13428.6 EMC93782.1 - 0.13 13.1 27.4 28 5.9 0.1 8.7 7 2 2 9 9 8 0 Tetratricopeptide repeat Bindin PF02084.15 EMC93782.1 - 0.14 12.5 2.0 23 5.1 0.0 3.7 2 2 2 4 4 4 0 Bindin SNAP PF14938.6 EMC93782.1 - 0.22 10.9 6.5 0.78 9.1 1.3 2.4 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP PPR_1 PF12854.7 EMC93782.1 - 0.27 11.0 2.3 68 3.3 0.1 4.4 4 0 0 4 4 3 0 PPR repeat TPR_3 PF07720.12 EMC93782.1 - 0.44 10.6 1.4 1.2e+02 2.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ArdA PF07275.11 EMC93782.1 - 1.3 9.6 4.3 79 3.8 2.7 3.6 1 1 1 2 2 2 0 Antirestriction protein (ArdA) SH3_1 PF00018.28 EMC93783.1 - 7.5e-09 35.1 1.0 1e-08 34.6 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EMC93783.1 - 2.4e-06 27.3 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMC93783.1 - 1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2303 PF10065.9 EMC93783.1 - 0.043 13.0 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) DUF2070 PF09843.9 EMC93783.1 - 0.56 8.4 6.2 0.74 8.0 6.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_U4 PF03419.13 EMC93783.1 - 2.2 7.5 12.0 3.1 7.0 12.0 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Catalase PF00199.19 EMC93784.1 - 9e-169 561.6 0.0 1.1e-168 561.2 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EMC93784.1 - 1.1e-16 60.7 0.0 2.2e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Abhydrolase_1 PF00561.20 EMC93786.1 - 3.3e-15 56.4 0.0 2.8e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC93786.1 - 1.2e-12 48.9 0.1 1.5e-12 48.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC93786.1 - 9.9e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF4048 PF13257.6 EMC93787.1 - 8.2e-23 81.5 2.7 8.2e-23 81.5 2.7 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) X PF00739.19 EMC93787.1 - 0.049 13.8 3.6 2 8.6 0.8 3.1 2 1 0 2 2 2 0 Trans-activation protein X GrpE PF01025.19 EMC93787.1 - 0.064 12.9 0.4 0.11 12.2 0.4 1.2 1 0 0 1 1 1 0 GrpE MBD_C PF14048.6 EMC93787.1 - 0.078 13.7 0.1 0.4 11.4 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 GAS PF13851.6 EMC93787.1 - 0.092 12.1 2.7 0.14 11.5 2.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Glyco_hydro_64 PF16483.5 EMC93788.1 - 2.1e-130 435.3 0.0 2.4e-130 435.1 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Glyco_hydro_2_C PF02836.17 EMC93789.1 - 4.2e-102 341.3 0.3 7.5e-102 340.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EMC93789.1 - 2.6e-67 227.0 0.0 4.8e-67 226.1 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EMC93789.1 - 5e-43 146.9 0.0 1.2e-42 145.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EMC93789.1 - 2.3e-22 79.3 0.3 1.1e-21 77.1 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EMC93789.1 - 1.9e-11 44.6 0.1 4.1e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EMC93789.1 - 0.001 19.6 0.1 0.0027 18.3 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain UvrA_DNA-bind PF17755.1 EMC93790.1 - 0.082 13.3 0.2 0.15 12.4 0.2 1.6 1 1 0 1 1 1 0 UvrA DNA-binding domain MFS_1 PF07690.16 EMC93791.1 - 3.6e-27 95.2 48.4 3.6e-27 95.2 48.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3742 PF12553.8 EMC93791.1 - 6.7 6.8 8.8 34 4.6 4.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3742) Exo_endo_phos PF03372.23 EMC93792.1 - 5.5e-06 26.1 0.0 1.4e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 2OG-FeII_Oxy_2 PF13532.6 EMC93794.1 - 8e-11 42.5 0.0 2.5e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rad50_zn_hook PF04423.14 EMC93794.1 - 0.25 11.2 1.2 0.63 9.9 1.2 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif DEAD PF00270.29 EMC93796.1 - 9.1e-15 54.9 0.0 2.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EMC93796.1 - 3.4e-10 40.2 0.0 7.8e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMC93796.1 - 4e-07 30.4 0.1 1.7e-06 28.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Sedlin_N PF04628.13 EMC93797.1 - 1.7e-42 144.7 0.0 2.6e-42 144.1 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EMC93797.1 - 6e-06 26.2 0.0 0.00017 21.6 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family L31 PF09784.9 EMC93798.1 - 5.6e-42 142.3 1.4 1.3e-23 83.3 0.4 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L31 DUF5324 PF17258.2 EMC93801.1 - 0.031 14.0 0.9 0.031 14.0 0.9 4.0 2 1 2 4 4 4 0 Family of unknown function (DUF5324) PRAI PF00697.22 EMC93801.1 - 0.12 12.1 3.3 0.065 13.0 0.9 1.8 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase BshC PF10079.9 EMC93801.1 - 0.18 10.5 2.1 0.22 10.2 0.8 1.7 1 1 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF148 PF02520.17 EMC93801.1 - 0.19 11.9 2.6 0.57 10.3 2.2 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF148 PMEI PF04043.15 EMC93801.1 - 0.25 11.7 12.3 0.25 11.7 0.3 2.7 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor F_actin_bind PF08919.10 EMC93801.1 - 0.56 10.3 4.9 6.6 6.9 0.2 3.7 3 1 1 4 4 4 0 F-actin binding DUF4085 PF13315.6 EMC93801.1 - 0.73 9.4 3.2 20 4.7 0.0 3.7 2 1 3 5 5 5 0 Protein of unknown function (DUF4085) Chlorosome_CsmC PF11098.8 EMC93801.1 - 2.5 8.1 13.8 15 5.6 0.1 4.1 3 1 1 4 4 4 0 Chlorosome envelope protein C DUF16 PF01519.16 EMC93801.1 - 6.5 7.3 7.0 5.1 7.6 1.2 3.1 3 1 0 3 3 3 0 Protein of unknown function DUF16 Cluap1 PF10234.9 EMC93801.1 - 9.1 5.6 8.5 6 6.2 6.1 1.9 2 1 0 2 2 2 0 Clusterin-associated protein-1 RINGv PF12906.7 EMC93802.1 - 2.1e-15 56.5 13.1 4.1e-15 55.6 13.1 1.5 1 0 0 1 1 1 1 RING-variant domain MscS_porin PF12795.7 EMC93802.1 - 0.029 13.9 7.1 0.05 13.1 7.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain zf-RING_2 PF13639.6 EMC93802.1 - 0.057 13.7 14.2 0.11 12.8 14.2 1.5 1 0 0 1 1 1 0 Ring finger domain Flagellin_C PF00700.21 EMC93802.1 - 0.077 13.4 0.5 0.17 12.2 0.5 1.5 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF745 PF05335.13 EMC93802.1 - 0.13 12.0 2.2 0.4 10.4 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PV-1 PF06637.11 EMC93802.1 - 0.36 9.6 1.8 0.81 8.4 1.8 1.5 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DivIC PF04977.15 EMC93802.1 - 0.42 10.4 3.4 0.97 9.3 3.4 1.5 1 0 0 1 1 1 0 Septum formation initiator Methyltransf_23 PF13489.6 EMC93803.1 - 7.9e-15 55.1 0.0 1.1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC93803.1 - 1.2e-12 48.4 0.0 2.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC93803.1 - 4.1e-12 46.1 0.0 1.4e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC93803.1 - 2.6e-11 44.0 0.0 4.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC93803.1 - 9.3e-10 39.1 0.0 4.3e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC93803.1 - 3.2e-06 26.8 0.0 4.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EMC93803.1 - 6.1e-05 22.6 0.0 9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 EMC93803.1 - 8.5e-05 22.7 0.0 9.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 EMC93803.1 - 0.00011 21.7 0.0 0.00022 20.6 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 EMC93803.1 - 0.0003 20.2 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain TPMT PF05724.11 EMC93803.1 - 0.00042 20.1 0.0 0.16 11.6 0.0 2.2 1 1 1 2 2 2 2 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.13 EMC93803.1 - 0.00073 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EMC93803.1 - 0.0012 17.9 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 EMC93803.1 - 0.0034 17.3 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EMC93803.1 - 0.0065 15.9 0.0 0.027 13.9 0.0 1.8 2 0 0 2 2 2 1 Tellurite resistance protein TehB DUF938 PF06080.12 EMC93803.1 - 0.0071 16.1 0.0 0.0096 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 EMC93803.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 EMC93803.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EMC93803.1 - 0.028 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EMC93803.1 - 0.048 13.6 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_17 PF12692.7 EMC93803.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase DREV PF05219.12 EMC93803.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase ArsB PF02040.15 EMC93804.1 - 9.7e-10 38.3 20.4 3.4e-09 36.5 7.6 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein TPR_1 PF00515.28 EMC93805.1 - 2e-37 125.5 4.2 1.8e-06 27.5 0.0 8.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 EMC93805.1 - 6e-36 119.7 13.2 3.1e-06 26.9 0.1 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC93805.1 - 1.8e-28 98.6 13.1 7.3e-21 74.2 0.2 4.4 4 0 0 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EMC93805.1 - 1.1e-25 87.6 9.3 0.0022 18.1 0.0 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMC93805.1 - 1.5e-20 72.1 20.8 0.00077 20.1 0.0 9.6 6 3 4 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 EMC93805.1 - 2.6e-20 71.8 10.7 0.00078 19.1 0.0 8.6 6 2 3 9 9 9 5 TPR repeat TPR_19 PF14559.6 EMC93805.1 - 4.3e-20 72.0 16.0 3.7e-06 27.4 0.6 7.3 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 EMC93805.1 - 1.3e-19 70.2 15.5 0.0011 19.2 0.0 7.9 7 1 2 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 EMC93805.1 - 8.6e-15 55.1 24.5 1.6e-05 25.5 0.0 7.6 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EMC93805.1 - 2.4e-12 46.3 8.2 0.15 12.5 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMC93805.1 - 6.8e-12 44.5 11.4 0.085 12.9 0.1 8.7 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 EMC93805.1 - 1.3e-08 34.9 14.2 0.23 12.2 0.3 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMC93805.1 - 1.5e-08 34.7 12.0 0.00028 21.0 0.9 6.0 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 EMC93805.1 - 2.4e-06 27.0 7.1 0.076 12.2 0.0 4.8 2 1 3 5 5 5 3 Tetratricopeptide repeat ChAPs PF09295.10 EMC93805.1 - 0.0069 15.4 0.8 1.3 8.0 0.0 3.1 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) YfiO PF13525.6 EMC93805.1 - 0.015 15.1 0.1 0.033 13.9 0.1 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_3 PF07720.12 EMC93805.1 - 0.039 14.0 0.1 10 6.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EMC93805.1 - 0.042 14.5 0.1 37 5.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMC93805.1 - 4.4 7.3 11.4 16 5.5 0.1 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TMEM208_SND2 PF05620.11 EMC93806.1 - 4.8e-54 182.6 0.2 5.4e-54 182.5 0.2 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 YwiC PF14256.6 EMC93806.1 - 0.0049 17.2 2.4 0.95 9.8 0.1 2.1 2 0 0 2 2 2 2 YwiC-like protein Acetyltransf_2 PF00797.17 EMC93807.1 - 1.7e-38 132.8 0.1 2.3e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 N-acetyltransferase FAD_binding_4 PF01565.23 EMC93808.1 - 6.7e-27 93.9 0.3 1.1e-26 93.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMC93808.1 - 0.005 16.9 0.1 0.022 14.9 0.1 2.1 1 0 0 1 1 1 1 Berberine and berberine like UL11 PF11094.8 EMC93808.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein EthD PF07110.11 EMC93809.1 - 2.4e-20 73.4 0.5 3e-20 73.1 0.5 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EMC93809.1 - 6.1e-08 33.1 0.3 1.4e-07 32.0 0.3 1.6 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase APC1_C PF18122.1 EMC93811.1 - 0.14 12.1 1.7 1.1 9.1 0.5 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex sub unit 1 C-terminal domain CoA_transf_3 PF02515.17 EMC93812.1 - 3.5e-64 217.2 0.0 4.2e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Peroxidase_2 PF01328.17 EMC93813.1 - 2.9e-44 151.8 0.0 4.1e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF1772 PF08592.11 EMC93815.1 - 3.5e-22 79.2 2.3 4e-22 79.0 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MgtC PF02308.16 EMC93815.1 - 0.23 11.8 2.7 0.29 11.5 2.7 1.1 1 0 0 1 1 1 0 MgtC family NAD_binding_10 PF13460.6 EMC93816.1 - 3.6e-20 72.6 0.0 4.2e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC93816.1 - 1.2e-05 25.0 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EMC93816.1 - 1.4e-05 25.5 0.0 3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMC93816.1 - 0.001 19.4 0.0 0.0019 18.5 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EMC93816.1 - 0.0018 17.8 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EMC93816.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EMC93816.1 - 0.0081 15.4 0.0 0.31 10.2 0.0 2.6 3 0 0 3 3 3 1 Male sterility protein Seadorna_VP6 PF07407.11 EMC93817.1 - 4.3 6.2 7.1 8.2 5.3 7.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP6 protein IMS PF00817.20 EMC93818.1 - 8.8e-42 142.6 0.0 1.3e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 EMC93818.1 - 4.1e-13 48.7 4.7 8.3e-13 47.7 4.7 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 EMC93818.1 - 5.6e-10 40.0 0.0 1.3e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EMC93818.1 - 0.0055 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-FPG_IleRS PF06827.14 EMC93818.1 - 0.045 13.6 0.8 0.045 13.6 0.8 1.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS UPF0547 PF10571.9 EMC93818.1 - 0.099 12.7 1.4 0.74 10.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF2052 PF09747.9 EMC93819.1 - 1.3e-21 77.6 14.0 1.8e-13 51.1 10.1 2.1 1 1 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) YEATS PF03366.16 EMC93820.1 - 3.3e-27 94.3 0.0 5.4e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 YEATS family SRP54 PF00448.22 EMC93821.1 - 8.1e-75 250.8 1.1 1.8e-74 249.7 1.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EMC93821.1 - 1.3e-31 109.1 3.3 1.3e-31 109.1 3.3 4.0 3 2 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 EMC93821.1 - 2.3e-17 62.9 0.2 5.1e-17 61.9 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EMC93821.1 - 1.4e-05 24.8 1.7 0.00011 21.8 1.4 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EMC93821.1 - 4.7e-05 23.6 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EMC93821.1 - 0.0008 19.8 0.1 0.0031 17.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 EMC93821.1 - 0.0018 18.4 0.0 0.005 16.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EMC93821.1 - 0.0036 17.0 0.4 0.012 15.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain APS_kinase PF01583.20 EMC93821.1 - 0.0046 16.9 0.2 0.011 15.6 0.0 1.7 2 0 0 2 2 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 EMC93821.1 - 0.0049 17.1 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC93821.1 - 0.01 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EMC93821.1 - 0.017 14.4 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.17 EMC93821.1 - 0.02 14.6 0.3 0.068 12.9 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.14 EMC93821.1 - 0.022 14.7 0.1 0.053 13.4 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 EMC93821.1 - 0.024 14.6 0.0 0.066 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EMC93821.1 - 0.025 13.9 0.0 0.058 12.7 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.17 EMC93821.1 - 0.045 13.5 0.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EMC93821.1 - 0.049 13.9 0.0 0.1 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMC93821.1 - 0.05 13.7 0.0 0.23 11.5 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase ResIII PF04851.15 EMC93821.1 - 0.054 13.5 0.6 0.16 11.9 0.6 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EMC93821.1 - 0.058 13.9 0.2 0.19 12.3 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMC93821.1 - 0.075 13.4 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMC93821.1 - 0.093 12.4 0.2 0.32 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 EMC93821.1 - 0.12 11.9 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor family VirC1 PF07015.11 EMC93821.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein Spectrin PF00435.21 EMC93821.1 - 0.15 12.5 0.9 0.46 11.0 0.2 2.0 2 0 0 2 2 2 0 Spectrin repeat GET2 PF08690.10 EMC93821.1 - 1.1 8.9 7.6 0.29 10.8 2.4 2.5 1 1 2 3 3 3 0 GET complex subunit GET2 Rrp15p PF07890.12 EMC93822.1 - 3.6e-38 130.9 8.9 3.6e-38 130.9 8.9 2.1 3 0 0 3 3 3 1 Rrp15p PI3K_1B_p101 PF10486.9 EMC93822.1 - 0.99 7.1 7.6 1.1 6.9 7.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Peptidase_S64 PF08192.11 EMC93822.1 - 1 7.8 6.1 1.3 7.5 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 RRN3 PF05327.11 EMC93822.1 - 1.5 7.3 12.5 1.8 7.0 12.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Apt1 PF10351.9 EMC93822.1 - 1.7 7.4 8.3 1.8 7.3 8.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 EMC93822.1 - 4.1 5.6 17.5 5.9 5.1 17.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EMC93822.1 - 4.3 5.4 25.9 8.4 4.5 25.9 1.4 1 1 0 1 1 1 0 Nop14-like family NMT1 PF09084.11 EMC93823.1 - 0.026 14.4 0.0 0.065 13.2 0.0 1.8 1 1 0 1 1 1 0 NMT1/THI5 like FixP_N PF14715.6 EMC93823.1 - 0.13 12.0 0.9 0.21 11.3 0.9 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP SAD_SRA PF02182.17 EMC93824.1 - 9e-41 139.2 0.2 1.4e-40 138.6 0.2 1.3 1 0 0 1 1 1 1 SAD/SRA domain FLILHELTA PF10306.9 EMC93825.1 - 1.6e-32 111.7 0.0 2.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EMC93825.1 - 0.0017 18.9 0.6 0.0018 18.8 0.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF1138 PF06592.13 EMC93825.1 - 0.039 14.0 0.2 0.088 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) ATP-synt_ab PF00006.25 EMC93826.1 - 4e-108 360.0 0.0 7.8e-108 359.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_M PF01031.20 EMC93826.1 - 1.1e-100 336.5 1.2 7.6e-100 333.8 0.0 2.6 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 EMC93826.1 - 2.7e-56 190.3 0.0 5.9e-56 189.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family ATP-synt_ab_Xtn PF16886.5 EMC93826.1 - 5.3e-44 149.0 0.0 1.2e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension GED PF02212.18 EMC93826.1 - 3.9e-29 100.6 8.2 8.4e-29 99.6 8.2 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain ATP-synt_ab_N PF02874.23 EMC93826.1 - 2.9e-15 56.5 1.7 7.8e-15 55.2 1.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain MMR_HSR1 PF01926.23 EMC93826.1 - 9.9e-05 22.4 0.3 0.0006 19.9 0.3 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EMC93826.1 - 0.018 15.4 0.0 3.1 8.1 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EMC93826.1 - 0.18 12.0 1.7 7.5 6.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain Aldo_ket_red PF00248.21 EMC93828.1 - 3.3e-53 180.8 0.0 4.1e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NMO PF03060.15 EMC93829.1 - 2.8e-54 184.7 0.1 7.1e-53 180.1 0.1 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EMC93829.1 - 5.9e-14 51.8 0.1 1.4e-12 47.3 0.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EMC93829.1 - 0.0022 17.1 0.0 0.0049 15.9 0.0 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EMC93829.1 - 0.03 13.5 0.3 0.28 10.3 0.3 2.1 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1729 PF08354.10 EMC93829.1 - 0.069 12.0 0.0 0.68 8.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1729) NanE PF04131.14 EMC93829.1 - 0.1 11.8 0.4 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EMC93829.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein FAT PF02259.23 EMC93830.1 - 5e-66 223.3 11.5 5e-66 223.3 11.5 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EMC93830.1 - 1.2e-31 110.5 0.5 4e-31 108.7 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EMC93830.1 - 8.2e-08 31.9 2.4 2.4e-07 30.4 0.4 2.7 2 0 0 2 2 2 1 FATC domain TPR_2 PF07719.17 EMC93830.1 - 0.037 14.1 0.9 17 5.8 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HRDC PF00570.23 EMC93830.1 - 0.62 10.1 2.2 0.89 9.6 0.3 2.4 2 0 0 2 2 2 0 HRDC domain TPR_1 PF00515.28 EMC93830.1 - 2.4 8.1 4.4 20 5.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_15 PF01793.16 EMC93831.1 - 1.4e-113 379.4 5.3 1.7e-113 379.2 5.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 EMC93832.1 - 2.1e-23 83.4 1.3 2.4e-23 83.3 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EMC93832.1 - 6.8e-14 52.0 4.9 6.8e-14 52.0 4.9 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 EMC93832.1 - 2.1e-07 29.7 0.0 3.9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Methyltransf_25 PF13649.6 EMC93833.1 - 9.4e-19 67.9 0.1 4.6e-17 62.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC93833.1 - 3.5e-18 66.0 0.1 1.3e-17 64.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC93833.1 - 7.4e-16 58.3 0.0 1.3e-15 57.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC93833.1 - 1.1e-10 42.2 0.0 3.6e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC93833.1 - 8.9e-10 38.3 0.0 2.9e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EMC93833.1 - 2.2e-08 34.1 0.0 3.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC93833.1 - 4.5e-06 26.3 0.0 9.2e-06 25.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EMC93833.1 - 3.1e-05 23.5 0.0 4.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 EMC93833.1 - 0.00022 21.0 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EMC93833.1 - 0.00042 20.3 0.0 0.0033 17.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EMC93833.1 - 0.0024 17.2 0.0 0.0038 16.5 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EMC93833.1 - 0.0097 15.3 0.6 0.059 12.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 EMC93833.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF2812 PF11193.8 EMC93833.1 - 0.048 13.9 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) Methyltransf_2 PF00891.18 EMC93833.1 - 0.09 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain CoaE PF01121.20 EMC93834.1 - 5.3e-42 143.5 0.0 3.7e-41 140.8 0.0 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 EMC93834.1 - 3.1e-05 24.2 0.0 0.00058 20.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMC93834.1 - 0.042 14.1 0.6 0.29 11.4 0.0 2.4 3 1 0 3 3 3 0 AAA domain SKI PF01202.22 EMC93834.1 - 0.14 12.2 0.0 1.8 8.7 0.0 2.4 2 1 0 2 2 2 0 Shikimate kinase TAF4 PF05236.14 EMC93835.1 - 1.1 9.0 5.7 2.8 7.6 5.7 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PfkB PF00294.24 EMC93836.1 - 1.1e-55 189.1 2.1 1.2e-55 188.9 2.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Asn_synthase PF00733.21 EMC93836.1 - 0.073 12.7 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Asparagine synthase FAD_binding_3 PF01494.19 EMC93839.1 - 2e-13 50.3 0.3 3.2e-12 46.4 0.3 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMC93839.1 - 0.0004 20.6 0.0 0.0053 17.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ANAPC3 PF12895.7 EMC93840.1 - 8e-22 77.3 17.0 7e-17 61.4 1.5 5.4 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EMC93840.1 - 5.6e-20 69.8 16.4 0.0026 17.7 0.3 10.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMC93840.1 - 1.5e-15 57.4 23.6 1.5e-05 25.4 1.0 7.9 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EMC93840.1 - 2.5e-15 55.5 11.8 0.0003 20.5 0.4 8.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMC93840.1 - 1.6e-13 50.7 23.6 1.3e-09 38.2 1.9 8.0 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMC93840.1 - 3e-12 47.0 15.3 0.02 15.5 0.2 6.9 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMC93840.1 - 1.3e-11 43.8 9.3 0.013 15.6 0.1 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMC93840.1 - 4.8e-07 30.1 30.0 0.041 14.7 1.2 10.0 7 3 4 11 11 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMC93840.1 - 2.2e-06 27.3 5.9 3.1 7.5 0.0 6.2 6 0 0 6 6 6 3 TPR repeat TPR_6 PF13174.6 EMC93840.1 - 1.3e-05 25.5 17.4 1 10.2 0.2 7.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 EMC93840.1 - 0.00043 20.1 0.9 0.00043 20.1 0.9 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMC93840.1 - 0.0012 18.7 16.6 0.096 12.8 0.2 8.1 10 0 0 10 10 9 1 Tetratricopeptide repeat PPR PF01535.20 EMC93840.1 - 0.0013 18.8 0.3 0.88 10.0 0.0 4.5 5 0 0 5 5 4 1 PPR repeat TPR_4 PF07721.14 EMC93840.1 - 0.005 17.3 20.0 0.049 14.3 3.3 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMC93840.1 - 0.0095 16.3 0.8 17 6.0 0.2 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EMC93840.1 - 0.027 14.8 6.0 2.3 8.6 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EMC93840.1 - 0.03 14.4 1.4 0.17 12.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_9 PF13371.6 EMC93840.1 - 0.27 11.4 16.4 0.4 10.9 0.4 6.2 4 3 3 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EMC93840.1 - 6.3 6.1 13.3 1.1 8.6 0.3 4.1 4 2 1 5 5 5 0 MalT-like TPR region DUF572 PF04502.13 EMC93841.1 - 2.2e-70 237.9 15.5 2.6e-70 237.7 15.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 EMC93841.1 - 0.043 13.9 3.9 2 8.5 0.5 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Cupin_8 PF13621.6 EMC93841.1 - 0.13 12.0 1.3 0.19 11.4 1.3 1.3 1 0 0 1 1 1 0 Cupin-like domain DNA_RNApol_7kD PF03604.13 EMC93841.1 - 0.17 11.6 2.0 11 5.8 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Lar_restr_allev PF14354.6 EMC93841.1 - 0.74 10.2 3.2 2.9 8.3 3.2 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar Ccdc124 PF06244.12 EMC93841.1 - 2.1 8.9 10.4 3.9 8.0 10.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 DUF1996 PF09362.10 EMC93842.1 - 2.4e-74 250.3 1.2 2.9e-74 250.0 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BCS1_N PF08740.11 EMC93843.1 - 1.1e-41 142.9 2.1 2.1e-41 142.0 2.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EMC93843.1 - 1.8e-08 34.9 0.0 4.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMC93843.1 - 0.009 16.4 0.2 0.03 14.7 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EMC93843.1 - 0.01 15.6 0.0 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EMC93843.1 - 0.023 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 KaiC P2_Phage_GpR PF06891.11 EMC93843.1 - 0.048 13.7 0.0 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) AAA_5 PF07728.14 EMC93843.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EMC93843.1 - 0.31 10.8 1.2 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain PBP1_TM PF14812.6 EMC93843.1 - 9 6.7 8.2 5.1 7.5 0.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L4 PF00573.22 EMC93844.1 - 4.9e-40 137.3 0.2 6.6e-40 136.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EMC93844.1 - 5.6e-27 93.6 0.1 1.3e-26 92.4 0.1 1.6 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain TAFII28 PF04719.14 EMC93845.1 - 4.1e-22 78.1 0.4 2.2e-19 69.3 0.3 2.2 2 0 0 2 2 2 2 hTAFII28-like protein conserved region DHHC PF01529.20 EMC93846.1 - 2.3e-26 92.5 1.8 2.3e-26 92.5 1.8 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase zf-CRD PF17979.1 EMC93846.1 - 0.024 14.8 0.3 0.037 14.1 0.3 1.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Homeobox_KN PF05920.11 EMC93849.1 - 4.9e-16 58.3 0.4 4.9e-16 58.3 0.4 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EMC93849.1 - 3.2e-10 39.7 0.3 5.9e-10 38.8 0.3 1.4 1 0 0 1 1 1 1 Homeodomain Sds3 PF08598.11 EMC93854.1 - 0.095 12.7 0.4 0.16 12.0 0.4 1.3 1 0 0 1 1 1 0 Sds3-like APC_u15 PF16636.5 EMC93854.1 - 0.13 12.7 1.8 8.4 6.9 0.6 2.7 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 APG17 PF04108.12 EMC93855.1 - 4.7e-119 398.0 9.7 5.6e-119 397.8 9.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Hydantoinase_B PF02538.14 EMC93855.1 - 0.007 14.8 0.4 0.007 14.8 0.4 1.5 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase EzrA PF06160.12 EMC93855.1 - 0.019 13.1 13.2 0.05 11.8 0.8 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF1804 PF08822.11 EMC93855.1 - 0.032 14.2 0.4 0.032 14.2 0.4 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF1804) ApoLp-III PF07464.11 EMC93855.1 - 0.032 14.3 3.0 4.1 7.5 0.4 3.9 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) MCPsignal PF00015.21 EMC93855.1 - 0.034 14.0 6.0 0.12 12.2 0.7 2.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2130 PF09903.9 EMC93855.1 - 0.035 13.4 8.1 1.3 8.3 1.1 3.3 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2130) KASH_CCD PF14662.6 EMC93855.1 - 0.1 12.4 6.6 0.38 10.6 0.2 2.9 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 EMC93855.1 - 0.65 10.4 10.5 0.23 11.9 0.9 3.0 2 1 1 3 3 3 0 Fez1 DASH_Spc19 PF08287.11 EMC93855.1 - 0.66 9.9 0.0 0.66 9.9 0.0 3.9 4 2 1 5 5 5 0 Spc19 Atg14 PF10186.9 EMC93855.1 - 0.79 8.7 10.2 2 7.4 4.6 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 EMC93855.1 - 0.81 10.0 10.0 24 5.3 0.1 3.2 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 EMC93855.1 - 1.4 9.0 8.7 22 5.1 0.5 4.2 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 EMC93855.1 - 1.4 8.6 10.7 6 6.6 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) STAT_alpha PF01017.20 EMC93855.1 - 1.7 8.5 8.1 3.9 7.3 0.3 3.2 3 0 0 3 3 3 0 STAT protein, all-alpha domain APG6_N PF17675.1 EMC93855.1 - 2.1 8.9 14.2 2.6 8.6 5.5 3.4 2 1 0 2 2 2 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 EMC93855.1 - 2.1 8.4 8.6 8.7 6.4 3.6 3.3 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 EMC93855.1 - 2.1 7.5 6.7 11 5.2 0.2 3.1 2 1 2 4 4 4 0 TMPIT-like protein Fib_alpha PF08702.10 EMC93855.1 - 2.2 8.5 6.5 3.1 8.0 0.8 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CdvA PF18822.1 EMC93855.1 - 2.7 7.8 7.5 1.1 9.2 0.6 3.4 2 2 0 3 3 3 0 CdvA-like coiled-coil domain WXG100 PF06013.12 EMC93855.1 - 4.1 7.7 14.7 0.3 11.3 0.6 4.8 4 2 2 6 6 4 0 Proteins of 100 residues with WXG YabA PF06156.13 EMC93855.1 - 7.1 7.3 9.1 47 4.7 0.2 3.9 2 2 0 2 2 2 0 Initiation control protein YabA DUF5082 PF16888.5 EMC93855.1 - 7.7 6.8 7.4 3.9 7.8 0.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) WD40 PF00400.32 EMC93856.1 - 8.7e-47 156.1 12.9 3.6e-09 37.1 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 EMC93856.1 - 2.4e-11 43.3 0.2 5e-11 42.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC93856.1 - 9.9e-11 41.2 0.2 2.4e-10 40.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EMC93856.1 - 4.1e-09 35.6 12.5 0.042 12.5 0.0 5.5 3 2 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EMC93856.1 - 6.3e-08 32.8 1.2 0.14 12.5 0.0 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EMC93856.1 - 9.6e-06 24.6 0.3 0.32 9.7 0.0 3.9 3 1 1 4 4 4 3 Nup133 N terminal like F-box_4 PF15966.5 EMC93856.1 - 0.027 14.4 0.0 0.083 12.8 0.0 1.9 1 0 0 1 1 1 0 F-box Abhydrolase_1 PF00561.20 EMC93857.1 - 9.7e-16 58.2 0.0 1.5e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC93857.1 - 1.2e-09 39.1 0.4 5.5e-09 37.0 0.4 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family YqjK PF13997.6 EMC93857.1 - 0.098 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 YqjK-like protein Y_phosphatase3 PF13350.6 EMC93858.1 - 2.5e-54 184.7 0.0 2.8e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EMC93858.1 - 1.8e-06 27.7 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EMC93858.1 - 2.7e-05 23.8 0.0 7.5e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EMC93858.1 - 0.026 14.4 0.0 0.077 12.8 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EMC93858.1 - 0.17 12.0 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate F-box PF00646.33 EMC93859.1 - 0.00047 19.9 0.8 0.00047 19.9 0.8 1.8 2 0 0 2 2 2 1 F-box domain Tudor_FRX1 PF18336.1 EMC93859.1 - 0.16 11.9 0.4 0.44 10.5 0.1 1.8 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain Ins_P5_2-kin PF06090.12 EMC93860.1 - 2.1e-44 152.3 0.1 3.3e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Thiamine_BP PF01910.17 EMC93861.1 - 1e-27 95.9 0.0 1.2e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Beta-lactamase PF00144.24 EMC93862.1 - 4.3e-39 134.7 0.0 6.3e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.32 EMC93863.1 - 2.5e-09 37.6 0.3 0.0036 18.1 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EMC93863.1 - 0.0038 16.2 0.0 0.095 11.6 0.0 2.4 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EMC93863.1 - 0.011 16.0 0.0 0.088 13.1 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EMC93863.1 - 0.15 11.3 0.0 3.4 6.9 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.18 EMC93864.1 - 1.7e-106 355.6 0.1 3.9e-106 354.4 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EMC93864.1 - 1.5e-05 25.0 0.0 3.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EMC93864.1 - 0.00048 20.2 1.9 0.93 9.5 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AAA_23 PF13476.6 EMC93864.1 - 0.0094 16.5 3.9 6.5 7.2 4.2 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EMC93864.1 - 0.051 13.5 0.3 0.051 13.5 0.3 2.6 3 1 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 EMC93864.1 - 0.085 12.4 0.3 5.2 6.6 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EMC93864.1 - 0.25 11.6 1.1 0.68 10.2 0.0 2.3 3 1 1 4 4 4 0 AAA domain Ribosomal_S16 PF00886.19 EMC93865.1 - 1.9e-21 75.9 0.1 3.2e-21 75.2 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S16 PHD PF00628.29 EMC93867.1 - 7.9e-11 41.7 0.8 7.9e-11 41.7 0.8 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EMC93867.1 - 0.0014 18.2 4.4 0.0023 17.4 4.4 1.3 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 EMC93867.1 - 0.018 14.9 3.3 0.053 13.4 3.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Pkinase PF00069.25 EMC93869.1 - 2.3e-51 174.7 0.0 3.4e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC93869.1 - 1e-27 97.0 0.0 3.5e-26 92.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC93869.1 - 9e-05 21.9 0.1 0.00033 20.1 0.1 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMC93869.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EMC93869.1 - 0.012 15.3 0.1 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EMC93869.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family V-ATPase_C PF03223.15 EMC93869.1 - 0.23 10.9 1.0 0.34 10.3 1.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit C Spermine_synth PF01564.17 EMC93870.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Haspin_kinase PF12330.8 EMC93871.1 - 2.7e-42 145.0 0.0 4e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RRM_1 PF00076.22 EMC93872.1 - 5.8e-17 61.3 0.0 8.5e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EMC93872.1 - 6e-06 26.7 9.0 6e-06 26.7 9.0 2.7 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EMC93872.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Isochorismatase PF00857.20 EMC93873.1 - 2.1e-47 161.6 0.0 2.7e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MIP PF00230.20 EMC93876.1 - 1.6e-46 158.9 16.9 2e-46 158.6 16.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Response_reg PF00072.24 EMC93878.1 - 1.4e-20 73.5 0.0 2.5e-14 53.4 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Dynactin_p62 PF05502.13 EMC93878.1 - 0.077 11.8 0.6 0.14 10.9 0.6 1.3 1 0 0 1 1 1 0 Dynactin p62 family DUF3605 PF12239.8 EMC93879.1 - 7e-59 198.5 0.0 8.3e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.24 EMC93880.1 - 2.1e-30 105.0 0.1 6.5e-30 103.4 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EMC93880.1 - 3.7e-27 95.1 0.0 5.7e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMC93880.1 - 1.1e-06 28.9 0.0 7.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EMC93880.1 - 0.19 12.0 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Oxidored_FMN PF00724.20 EMC93881.1 - 3.8e-86 289.5 0.0 4.4e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 EMC93882.1 - 1.6e-45 155.6 45.2 1.8e-44 152.1 45.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC93882.1 - 8.2e-22 77.4 8.1 8.2e-22 77.4 8.1 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMC93882.1 - 3.5e-14 52.5 11.7 3.5e-14 52.5 11.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter Polysacc_deac_1 PF01522.21 EMC93883.1 - 1.8e-15 57.0 0.0 2.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1932 PF09130.11 EMC93883.1 - 0.089 12.8 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Fungal_trans PF04082.18 EMC93884.1 - 8.8e-18 64.3 0.2 1.3e-17 63.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93884.1 - 1.3e-07 31.6 12.2 2.5e-07 30.7 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 EMC93885.1 - 9.1e-85 285.0 46.6 1.1e-84 284.8 46.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.21 EMC93886.1 - 1.3e-71 241.9 0.1 2.5e-71 241.0 0.1 1.4 1 1 0 1 1 1 1 Amidase Abhydrolase_3 PF07859.13 EMC93887.1 - 2e-30 106.2 0.0 2.5e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMC93887.1 - 0.00015 20.7 0.0 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase HET PF06985.11 EMC93889.1 - 5.2e-05 23.6 0.2 0.00042 20.7 0.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 EMC93890.1 - 1.6e-12 48.0 0.2 1.8e-12 47.8 0.2 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HPTransfase PF10090.9 EMC93890.1 - 0.024 14.5 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain MCM PF00493.23 EMC93891.1 - 1.2e-104 348.3 0.0 2.2e-104 347.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMC93891.1 - 3.6e-35 120.6 0.1 9.8e-35 119.2 0.0 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EMC93891.1 - 2.7e-28 98.2 3.0 6.6e-28 97.0 3.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMC93891.1 - 6.9e-15 55.5 0.2 1.6e-14 54.3 0.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMC93891.1 - 2.8e-06 26.9 0.0 0.00026 20.5 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMC93891.1 - 2.5e-05 24.3 0.0 6.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EMC93891.1 - 0.00061 19.6 0.0 0.0024 17.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GntR PF00392.21 EMC93891.1 - 0.0073 15.9 2.0 0.11 12.2 1.4 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Sigma54_activat PF00158.26 EMC93891.1 - 0.041 13.6 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Vps54 PF07928.12 EMC93892.1 - 3.5e-47 160.2 0.0 1.1e-46 158.6 0.0 1.9 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 EMC93892.1 - 1.8e-07 30.7 0.2 6.6e-07 28.9 0.2 1.9 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EMC93892.1 - 0.084 13.0 1.5 0.3 11.2 1.5 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FliJ PF02050.16 EMC93892.1 - 0.12 12.6 4.9 0.079 13.2 1.1 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.11 EMC93892.1 - 0.17 10.7 1.0 0.33 9.8 1.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 EMC93892.1 - 5.5 7.2 14.4 0.14 12.3 0.9 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) AMP-binding PF00501.28 EMC93893.1 - 3.8e-69 233.3 0.0 4.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC93893.1 - 9.4e-13 48.9 0.0 4e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain DGC PF08859.11 EMC93895.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 DGC domain NICE-1 PF15845.5 EMC93895.1 - 0.19 12.5 2.3 0.36 11.6 2.3 1.4 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family PhoLip_ATPase_C PF16212.5 EMC93896.1 - 5.3 6.7 12.0 13 5.5 12.0 1.7 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal Fungal_trans PF04082.18 EMC93897.1 - 3e-14 52.7 0.1 5e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93897.1 - 2.2e-06 27.7 7.2 4e-06 26.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 EMC93898.1 - 8.2e-40 137.4 0.7 1.2e-39 136.9 0.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase HET PF06985.11 EMC93899.1 - 2.4e-29 102.6 0.2 3.1e-29 102.2 0.2 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COG2 PF06148.11 EMC93901.1 - 2.1e-29 102.3 0.4 1.4e-28 99.6 0.0 2.3 2 1 1 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EMC93901.1 - 1.4e-06 28.3 0.0 5.8e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 EMC93901.1 - 0.013 15.6 0.0 0.038 14.2 0.0 1.8 2 1 0 2 2 2 0 Golgi transport complex subunit 5 NUDIX PF00293.28 EMC93902.1 - 9.3e-16 58.1 0.1 2.5e-15 56.7 0.1 1.7 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.11 EMC93902.1 - 1.6e-12 48.0 0.0 3.3e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EMC93902.1 - 4.7e-06 26.2 1.4 8.9e-06 25.3 1.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ribosomal_L1 PF00687.21 EMC93903.1 - 7.9e-30 104.1 0.0 9.1e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Adap_comp_sub PF00928.21 EMC93905.1 - 5.2e-91 304.7 0.0 1.1e-90 303.6 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMC93905.1 - 4.5e-10 39.6 0.2 7.1e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L27 PF01016.19 EMC93906.1 - 1.9e-29 101.5 0.2 3e-29 100.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein AMP-binding PF00501.28 EMC93908.1 - 8.4e-41 139.9 0.0 1.2e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EMC93908.1 - 1.3e-05 25.0 0.4 1.3e-05 25.0 0.4 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus p450 PF00067.22 EMC93909.1 - 9.6e-43 146.6 0.0 2.7e-42 145.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_88 PF07470.13 EMC93910.1 - 3.7e-17 62.4 1.8 5.8e-17 61.8 1.7 1.3 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 TrkH PF02386.16 EMC93911.1 - 4.6e-146 487.2 9.8 2.5e-145 484.8 3.8 2.1 2 0 0 2 2 2 2 Cation transport protein SCAB_CC PF16712.5 EMC93911.1 - 0.086 12.7 0.7 0.15 11.9 0.7 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein ECM11 PF15463.6 EMC93911.1 - 0.2 12.2 1.0 0.43 11.2 1.0 1.5 1 0 0 1 1 1 0 Extracellular mutant protein 11 GATase_5 PF13507.6 EMC93912.1 - 1.7e-97 325.6 0.0 2.4e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EMC93912.1 - 1.1e-34 119.9 1.5 6.2e-23 81.6 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EMC93912.1 - 7.1e-33 113.0 0.0 1.3e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EMC93912.1 - 2.9e-23 82.1 0.0 6.5e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain TruB_C PF09142.11 EMC93912.1 - 0.077 12.8 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal AIRS PF00586.24 EMC93912.1 - 0.19 12.4 0.7 2.3 8.9 0.0 2.9 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain Tau95_N PF17682.1 EMC93914.1 - 2e-33 115.3 0.0 3.8e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 EMC93914.1 - 2e-29 103.2 0.2 3.6e-29 102.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Dev_Cell_Death PF10539.9 EMC93914.1 - 0.0034 17.2 0.1 0.0088 15.9 0.0 1.6 2 0 0 2 2 2 1 Development and cell death domain Polyketide_cyc2 PF10604.9 EMC93914.1 - 0.017 15.4 0.0 3.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport B56 PF01603.20 EMC93915.1 - 6.5e-191 634.8 4.2 7.7e-191 634.5 4.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EMC93915.1 - 0.0056 16.6 1.4 2 8.3 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SPX PF03105.19 EMC93915.1 - 7.6 6.3 8.2 16 5.3 8.2 1.4 1 0 0 1 1 1 0 SPX domain COX5A PF02284.16 EMC93916.1 - 2.3e-40 136.7 0.4 2.7e-40 136.5 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.18 EMC93917.1 - 1.2e-60 205.2 19.3 1.4e-60 204.9 19.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Pkinase PF00069.25 EMC93918.1 - 4.7e-38 131.1 0.0 7.2e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC93918.1 - 1.4e-21 77.0 0.0 3.5e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMC93918.1 - 0.0057 16.0 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HET PF06985.11 EMC93918.1 - 0.052 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) CAF1C_H4-bd PF12265.8 EMC93920.1 - 1.8e-23 82.6 0.2 5.9e-23 80.9 0.2 2.0 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EMC93920.1 - 1.3e-22 79.6 11.9 1.8e-05 25.4 1.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Frtz PF11768.8 EMC93920.1 - 0.00042 18.8 0.0 0.0081 14.5 0.0 2.0 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 EMC93920.1 - 0.0015 18.8 0.0 1 9.7 0.0 3.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MafB PF06255.13 EMC93920.1 - 0.047 13.1 0.3 0.084 12.3 0.3 1.3 1 0 0 1 1 1 0 Neisseria toxin MafB DUF3995 PF13160.6 EMC93921.1 - 0.046 14.1 0.0 0.054 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) zf-H2C2_5 PF13909.6 EMC93922.1 - 1.5e-05 24.6 0.8 7.9e-05 22.3 0.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EMC93922.1 - 0.64 10.6 13.9 0.28 11.7 0.1 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type Ank_4 PF13637.6 EMC93923.1 - 7e-11 42.4 0.1 9.7e-06 26.0 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMC93923.1 - 2.2e-10 40.6 0.1 3.2e-09 36.9 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMC93923.1 - 5.7e-10 39.6 0.1 1.8e-09 38.0 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMC93923.1 - 8e-07 28.9 0.0 7.6e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EMC93923.1 - 9.6e-07 29.0 0.1 3.6e-05 24.0 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat SKIP_SNW PF02731.15 EMC93924.1 - 3e-70 235.0 8.2 3e-70 235.0 8.2 2.2 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.12 EMC93924.1 - 0.31 10.8 22.6 0.63 9.7 22.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PKK PF12474.8 EMC93924.1 - 6.1 7.0 30.1 7.7 6.6 27.5 2.3 2 1 0 2 2 2 0 Polo kinase kinase UPF0029 PF01205.19 EMC93925.1 - 4.7e-35 120.1 0.0 6.7e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EMC93925.1 - 1.4e-05 25.3 0.0 4.6e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 RWD domain p450 PF00067.22 EMC93926.1 - 1.4e-56 192.2 0.0 1.8e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SEP PF08059.13 EMC93927.1 - 2.9e-24 85.4 0.0 7.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EMC93927.1 - 1.1e-15 57.5 0.0 2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EMC93927.1 - 2.4e-13 49.6 0.3 4.1e-13 48.9 0.3 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EMC93927.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain FAA_hydrolase PF01557.18 EMC93927.1 - 0.055 13.1 0.2 0.33 10.6 0.1 2.0 2 0 0 2 2 2 0 Fumarylacetoacetate (FAA) hydrolase family UBA PF00627.31 EMC93927.1 - 0.096 12.6 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 UBA/TS-N domain CD99L2 PF12301.8 EMC93927.1 - 5.6 7.2 16.5 3.4 7.9 12.3 2.4 2 0 0 2 2 2 0 CD99 antigen like protein 2 TOM13 PF08219.11 EMC93928.1 - 4.9e-38 129.0 0.0 6.3e-38 128.6 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 DHDPS PF00701.22 EMC93929.1 - 3.7e-31 107.9 0.0 1.5e-30 105.9 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 EMC93930.1 - 1.6e-34 119.4 38.2 1.6e-34 119.4 38.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.16 EMC93931.1 - 2.6e-49 168.4 0.6 3.1e-49 168.2 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.18 EMC93932.1 - 3.4e-19 68.9 0.0 5e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC93932.1 - 2.4e-05 24.3 10.8 2.4e-05 24.3 10.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 60KD_IMP PF02096.20 EMC93933.1 - 6.2e-14 52.2 0.1 8.4e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Fer2 PF00111.27 EMC93934.1 - 2.5e-13 49.8 0.8 2.5e-13 49.8 0.8 1.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 EMC93935.1 - 1.9e-12 46.9 0.1 0.0093 15.9 0.0 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein MotA_ExbB PF01618.16 EMC93935.1 - 0.12 12.1 0.0 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Sugar_tr PF00083.24 EMC93936.1 - 1.5e-24 86.7 28.5 2.1e-16 59.8 7.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Tim17 PF02466.19 EMC93937.1 - 6.3e-38 129.6 8.1 7.9e-38 129.3 8.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 EMC93937.1 - 0.049 13.6 2.4 0.093 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) ABA_WDS PF02496.16 EMC93937.1 - 7.8 7.1 5.1 35 5.0 0.1 2.6 3 0 0 3 3 3 0 ABA/WDS induced protein Glyco_hydro_10 PF00331.20 EMC93939.1 - 1.9e-70 237.5 0.0 2.4e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4667 PF15700.5 EMC93939.1 - 6.4 6.8 16.5 13 5.8 16.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) ANAPC8 PF04049.13 EMC93940.1 - 2.3e-48 163.8 0.1 4.2e-48 163.0 0.1 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EMC93940.1 - 5e-18 64.1 15.8 0.00042 20.0 0.0 6.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EMC93940.1 - 5.8e-14 51.0 21.9 0.023 14.8 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EMC93940.1 - 2.7e-13 49.0 15.8 4.7e-05 23.3 0.0 7.2 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMC93940.1 - 7.3e-12 45.1 19.5 0.0061 17.3 0.1 8.4 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EMC93940.1 - 6.2e-11 42.8 11.8 5.3e-05 23.8 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMC93940.1 - 6.9e-11 41.7 14.1 5.7e-05 22.7 0.5 6.1 4 3 3 7 7 7 4 TPR repeat TPR_7 PF13176.6 EMC93940.1 - 2.1e-05 24.2 8.0 0.49 10.5 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC93940.1 - 0.00054 20.1 10.1 0.24 11.7 0.2 4.6 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EMC93940.1 - 0.0011 19.2 11.5 13 6.4 0.9 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMC93940.1 - 0.0016 19.0 19.0 0.24 12.1 0.0 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMC93940.1 - 0.0016 18.7 16.4 2.4 8.5 0.0 6.2 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EMC93940.1 - 0.0033 16.7 14.1 0.13 11.5 0.4 4.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMC93940.1 - 0.0037 17.7 0.0 0.0037 17.7 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat ChAPs PF09295.10 EMC93940.1 - 0.024 13.6 0.1 8.7 5.2 0.0 2.8 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) G_glu_transpept PF01019.21 EMC93940.1 - 0.05 12.4 0.1 0.082 11.7 0.1 1.3 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase DUF3856 PF12968.7 EMC93940.1 - 0.088 12.9 0.7 0.97 9.5 0.6 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) CCP_MauG PF03150.14 EMC93940.1 - 0.11 13.2 0.3 3.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase TPR_9 PF13371.6 EMC93940.1 - 0.3 11.3 19.4 0.65 10.2 0.3 5.0 5 2 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMC93940.1 - 1.7 8.7 6.9 62 3.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat polyprenyl_synt PF00348.17 EMC93941.1 - 3e-94 314.9 0.1 3.7e-94 314.6 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 EMC93941.1 - 1.4e-05 25.3 0.9 3.8e-05 23.9 0.6 1.8 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain AAA_15 PF13175.6 EMC93941.1 - 0.01 15.6 1.3 0.015 15.0 1.3 1.1 1 0 0 1 1 1 0 AAA ATPase domain BST2 PF16716.5 EMC93941.1 - 0.017 15.7 1.4 0.036 14.7 1.4 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 YkyB PF14177.6 EMC93941.1 - 0.093 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 YkyB-like protein adh_short_C2 PF13561.6 EMC93942.1 - 9e-29 100.7 0.0 1.3e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC93942.1 - 1.1e-24 87.0 0.0 1.4e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EMC93942.1 - 0.00017 21.1 0.0 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EMC93942.1 - 0.002 18.5 0.0 0.0059 17.0 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 EMC93942.1 - 0.0051 16.2 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EMC93942.1 - 0.0063 16.4 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 EMC93942.1 - 0.0075 16.2 0.6 0.053 13.4 0.6 2.3 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EMC93942.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 EMC93942.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMC93942.1 - 0.082 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 EMC93942.1 - 0.15 11.6 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 EMC93942.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.6 2 0 0 2 2 1 0 TrkA-N domain adh_short PF00106.25 EMC93945.1 - 5.3e-15 55.4 0.0 5e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93945.1 - 9.1e-08 31.9 0.0 1.8e-07 31.0 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC93945.1 - 2e-07 31.1 0.0 3.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EMC93945.1 - 0.004 17.4 0.2 0.0089 16.3 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMC93945.1 - 0.0066 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 EMC93945.1 - 0.041 13.0 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DNA_ligase_A_N PF04675.14 EMC93946.1 - 3.9e-24 85.9 0.0 7.2e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 EMC93946.1 - 6.3e-23 81.5 0.0 1.1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EMC93946.1 - 0.00018 21.8 0.0 0.00037 20.9 0.0 1.4 1 0 0 1 1 1 1 RNA ligase AMP-binding PF00501.28 EMC93947.1 - 9.4e-18 64.0 0.0 2.5e-17 62.6 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme NPCC PF08058.11 EMC93948.1 - 1.2e-20 73.9 0.0 1.9e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore complex component Med3 PF11593.8 EMC93948.1 - 2 7.5 10.9 3.6 6.7 10.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Oxidored_molyb PF00174.19 EMC93949.1 - 1.1e-58 197.6 0.1 1.6e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EMC93949.1 - 5.9e-22 78.2 0.1 1.1e-21 77.3 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 EMC93949.1 - 0.087 13.6 0.1 0.18 12.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig domain NAD_binding_10 PF13460.6 EMC93950.1 - 4e-14 52.9 0.0 6.5e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC93950.1 - 8.3e-06 25.5 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EMC93950.1 - 0.0005 20.0 0.2 0.0022 18.0 0.2 2.0 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 EMC93950.1 - 0.0035 16.4 0.0 0.0062 15.6 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMC93950.1 - 0.022 14.2 0.1 0.053 13.0 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EMC93950.1 - 0.11 13.0 0.0 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EMC93950.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Ribonuclease_T2 PF00445.18 EMC93952.1 - 3.6e-38 131.6 0.0 5.9e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family SAM_decarbox PF01536.16 EMC93953.1 - 8.3e-132 439.5 0.0 6.5e-131 436.5 0.0 1.9 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase EHN PF06441.12 EMC93954.1 - 3.9e-31 107.6 0.2 5.1e-31 107.3 0.2 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMC93954.1 - 0.00088 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC93954.1 - 0.00092 19.9 0.6 0.0013 19.4 0.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Acetyltransf_10 PF13673.7 EMC93956.1 - 9.3e-08 32.1 0.0 1.7e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC93956.1 - 3.3e-07 30.6 0.0 5.3e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC93956.1 - 1.4e-06 28.7 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC93956.1 - 0.025 14.6 0.0 0.087 12.8 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein AA_permease_2 PF13520.6 EMC93957.1 - 1.1e-58 199.0 53.4 1.4e-58 198.8 53.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC93957.1 - 4.7e-18 65.0 44.9 6.3e-18 64.6 44.9 1.1 1 0 0 1 1 1 1 Amino acid permease Forkhead PF00250.18 EMC93957.1 - 0.041 14.1 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Forkhead domain Tweety PF04906.13 EMC93957.1 - 0.31 9.7 1.0 0.65 8.6 1.0 1.5 1 0 0 1 1 1 0 Tweety SecE PF00584.20 EMC93957.1 - 0.32 10.9 0.1 0.32 10.9 0.1 4.0 3 1 1 4 4 4 0 SecE/Sec61-gamma subunits of protein translocation complex Metallophos PF00149.28 EMC93959.1 - 5.7e-36 124.9 0.1 1.1e-35 124.0 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Polyketide_cyc2 PF10604.9 EMC93961.1 - 3.7e-10 40.2 0.3 2.2e-09 37.7 0.3 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EMC93961.1 - 7.8e-07 29.4 0.1 9.3e-07 29.1 0.1 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EMC93961.1 - 0.0024 18.1 0.3 0.0054 17.0 0.3 1.7 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein p450 PF00067.22 EMC93962.1 - 1.8e-30 106.1 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LCCL PF03815.19 EMC93964.1 - 3.9e-20 71.8 0.0 6e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.21 EMC93965.1 - 9e-11 41.5 0.0 2.7e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II ABC2_membrane PF01061.24 EMC93966.1 - 3.4e-76 255.3 53.1 7.5e-40 136.6 16.0 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EMC93966.1 - 8.1e-33 113.8 0.0 1.3e-15 58.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EMC93966.1 - 8.7e-28 96.1 7.0 4.9e-25 87.2 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EMC93966.1 - 1.7e-16 60.6 0.1 5e-16 59.1 0.1 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EMC93966.1 - 5.9e-06 26.8 0.1 0.00079 19.9 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EMC93966.1 - 6.9e-06 26.3 0.0 0.0036 17.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 EMC93966.1 - 7.5e-06 26.0 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMC93966.1 - 0.00016 21.3 0.2 0.011 15.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EMC93966.1 - 0.00018 22.1 0.0 0.0063 17.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EMC93966.1 - 0.0005 19.7 0.2 0.015 14.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EMC93966.1 - 0.0013 18.7 0.0 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_17 PF13207.6 EMC93966.1 - 0.0015 19.0 0.0 0.76 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMC93966.1 - 0.0058 16.9 0.7 0.22 11.8 0.1 2.9 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 EMC93966.1 - 0.011 14.8 46.8 0.0094 15.1 22.1 2.9 2 1 1 3 3 3 0 ABC-2 family transporter protein SMC_N PF02463.19 EMC93966.1 - 0.012 15.0 0.0 0.19 11.1 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EMC93966.1 - 0.022 14.5 0.2 2.2 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMC93966.1 - 0.022 15.0 0.1 1 9.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMC93966.1 - 0.051 14.0 0.0 14 6.1 0.0 3.1 3 0 0 3 3 3 0 RNA helicase NACHT PF05729.12 EMC93966.1 - 0.055 13.4 0.2 3.7 7.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 EMC93966.1 - 0.062 12.9 0.7 0.76 9.3 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EMC93966.1 - 0.14 12.7 0.0 0.56 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMC93966.1 - 0.16 11.6 0.3 8.8 6.0 0.0 3.3 4 0 0 4 4 4 0 AAA domain Opi1 PF08618.10 EMC93967.1 - 6.3e-28 98.2 16.2 1.5e-20 73.9 2.7 3.5 3 1 1 4 4 4 3 Transcription factor Opi1 SOG2 PF10428.9 EMC93967.1 - 0.17 11.1 4.6 0.27 10.4 4.5 1.6 1 1 0 1 1 1 0 RAM signalling pathway protein SKG6 PF08693.10 EMC93968.1 - 0.012 15.0 0.2 0.023 14.1 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ecm33 PF12454.8 EMC93968.1 - 0.019 15.1 1.2 0.056 13.6 1.2 1.8 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TMEM51 PF15345.6 EMC93968.1 - 0.033 14.0 0.1 0.054 13.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 LRR_9 PF14580.6 EMC93968.1 - 0.43 10.1 2.6 1.4 8.4 1.7 2.0 1 1 1 2 2 2 0 Leucine-rich repeat MFS_1 PF07690.16 EMC93969.1 - 8.4e-37 126.9 49.0 1.3e-35 123.0 40.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC93969.1 - 1.1e-07 31.2 13.3 1.1e-07 31.2 13.3 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter DUF3796 PF12676.7 EMC93969.1 - 4.1 7.9 10.7 7.4 7.0 1.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3796) Pam17 PF08566.10 EMC93969.1 - 4.4 7.1 4.6 4.7 7.0 0.7 2.7 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 Ribosomal_L19 PF01245.20 EMC93971.1 - 5.2e-12 45.7 0.1 9e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Asp PF00026.23 EMC93972.1 - 2.7e-57 194.6 2.1 3e-57 194.4 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMC93972.1 - 5.8e-05 23.4 3.1 0.0006 20.1 2.8 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EMC93972.1 - 0.13 12.0 0.1 0.77 9.5 0.0 2.3 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal TF_Otx PF03529.13 EMC93972.1 - 0.31 11.5 2.9 3.3 8.2 0.0 3.1 2 1 1 3 3 3 0 Otx1 transcription factor adh_short PF00106.25 EMC93974.1 - 7.7e-22 77.7 0.1 1e-10 41.4 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC93974.1 - 2.6e-18 66.4 0.1 1.7e-10 40.9 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC93974.1 - 5.2e-07 29.8 1.7 2.7e-05 24.2 0.6 2.2 1 1 1 2 2 2 2 KR domain Epimerase PF01370.21 EMC93974.1 - 0.0083 15.6 0.2 0.053 13.0 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC93974.1 - 0.12 12.3 2.1 0.34 10.8 1.8 1.8 2 0 0 2 2 2 0 NAD(P)H-binding GATase_6 PF13522.6 EMC93976.1 - 4.4e-08 33.4 0.1 7.9e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EMC93976.1 - 2.3e-06 26.7 0.1 1.5e-05 24.0 0.1 2.3 1 1 0 1 1 1 1 Glutamine amidotransferases class-II DUF1556 PF07590.11 EMC93978.1 - 0.11 12.8 1.8 13 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) CoA_trans PF01144.23 EMC93979.1 - 2.9e-96 321.1 2.3 7.4e-57 192.2 0.5 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EMC93979.1 - 0.023 14.7 0.6 0.056 13.4 0.0 1.9 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 EMC93979.1 - 0.086 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Glyco_hydro_127 PF07944.12 EMC93981.1 - 2.3e-17 62.7 0.2 1.3e-16 60.2 0.1 2.0 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 NAD_binding_10 PF13460.6 EMC93982.1 - 3.3e-07 30.4 0.0 4.4e-06 26.7 0.0 2.6 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EMC93982.1 - 0.00073 18.6 0.0 0.0022 17.1 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMC93982.1 - 0.00085 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMC93982.1 - 0.01 15.0 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 EMC93982.1 - 0.04 13.0 0.0 0.45 9.6 0.0 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain CAP PF00188.26 EMC93983.1 - 1.4e-18 67.9 3.0 3.5e-18 66.6 3.0 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF3915 PF13054.6 EMC93990.1 - 0.059 13.4 1.5 0.098 12.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) GST_N_3 PF13417.6 EMC93991.1 - 0.0091 16.4 0.1 0.017 15.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HD_4 PF13328.6 EMC93992.1 - 0.007 16.1 0.2 1.1 9.0 0.0 2.7 2 1 1 3 3 3 2 HD domain MbeD_MobD PF04899.12 EMC93992.1 - 0.074 13.2 0.5 0.16 12.1 0.1 1.7 2 0 0 2 2 2 0 MbeD/MobD like Glyco_hydro_17 PF00332.18 EMC93993.1 - 2e-13 50.6 2.5 4.5e-13 49.5 2.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 NAD_binding_10 PF13460.6 EMC93994.1 - 4.6e-23 82.1 0.0 5.6e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC93994.1 - 3.7e-11 43.0 0.0 5.4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMC93994.1 - 1.7e-07 30.9 0.0 3.9e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMC93994.1 - 0.001 19.3 0.0 0.0016 18.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EMC93994.1 - 0.0034 17.6 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain IBR PF01485.21 EMC93995.1 - 5.6e-16 58.5 35.9 1.3e-08 34.9 11.8 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Sgf11 PF08209.11 EMC93995.1 - 0.0029 17.1 0.1 0.0029 17.1 0.1 3.7 5 0 0 5 5 5 1 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 EMC93995.1 - 0.93 9.1 0.0 0.93 9.1 0.0 4.7 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Carboxyl_trans PF01039.22 EMC93996.1 - 2.7e-139 465.0 0.1 3.4e-139 464.7 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.24 EMC93997.1 - 2.4e-38 131.7 1.2 5e-38 130.7 1.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMC93997.1 - 5.9e-31 107.5 0.0 1.4e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EMC93997.1 - 1.2e-28 99.2 0.1 2.3e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMC93997.1 - 6.1e-13 49.2 0.1 1.3e-12 48.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EMC93997.1 - 6.8e-07 29.2 0.1 2.4e-06 27.4 0.1 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal BTB PF00651.31 EMC93998.1 - 9.3e-06 25.9 0.1 1.4e-05 25.3 0.0 1.4 2 0 0 2 2 2 1 BTB/POZ domain MIP PF00230.20 EMC93999.1 - 5.9e-48 163.5 15.9 7.7e-48 163.2 15.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.24 EMC94000.1 - 1.2e-109 367.2 25.7 1.4e-109 367.0 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC94000.1 - 2.1e-22 79.5 44.6 1.5e-16 60.3 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Apolipoprotein PF01442.18 EMC94001.1 - 0.021 14.7 15.7 3 7.7 0.8 4.9 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain MPP6 PF10175.9 EMC94002.1 - 2.5e-07 31.3 3.7 0.0068 16.9 0.0 2.2 2 0 0 2 2 2 2 M-phase phosphoprotein 6 Amidase PF01425.21 EMC94003.1 - 1.9e-27 96.3 0.2 3.5e-27 95.5 0.2 1.3 1 0 0 1 1 1 1 Amidase Gpr1_Fun34_YaaH PF01184.19 EMC94004.1 - 4.4e-21 75.5 9.2 5.3e-21 75.2 9.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family GerA PF03323.13 EMC94004.1 - 0.18 10.2 2.0 1.2 7.5 0.1 2.3 2 1 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Transp_cyt_pur PF02133.15 EMC94005.1 - 5.9e-18 64.9 33.1 8e-18 64.4 33.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DEAD PF00270.29 EMC94006.1 - 7.5e-41 139.8 0.4 1.3e-40 139.1 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC94006.1 - 2.2e-29 102.1 0.5 1.2e-28 99.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC94006.1 - 3.3e-07 30.5 0.0 8.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EMC94006.1 - 0.00054 18.8 0.0 0.00088 18.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cupin_2 PF07883.11 EMC94008.1 - 1.5e-14 53.5 1.4 1.7e-14 53.2 0.1 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_6 PF12852.7 EMC94008.1 - 0.00015 21.5 0.1 0.00017 21.4 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EMC94008.1 - 0.00015 21.6 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EMC94008.1 - 0.00086 18.9 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EMC94008.1 - 0.0023 17.6 0.1 0.0047 16.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 EMC94008.1 - 0.041 14.1 1.4 0.086 13.0 0.0 1.9 1 1 1 2 2 2 0 ARD/ARD' family MFS_1 PF07690.16 EMC94009.1 - 9.3e-31 107.0 21.0 9.3e-31 107.0 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC94009.1 - 1.7e-09 37.1 1.0 1.7e-09 37.1 1.0 3.4 3 1 1 4 4 4 1 Sugar (and other) transporter DUF1772 PF08592.11 EMC94009.1 - 0.059 13.7 0.0 0.059 13.7 0.0 3.3 3 2 0 3 3 3 0 Domain of unknown function (DUF1772) Tautomerase_2 PF14552.6 EMC94010.1 - 1.9e-29 101.6 0.0 4.3e-29 100.4 0.0 1.5 2 0 0 2 2 2 1 Tautomerase enzyme Tautomerase PF01361.21 EMC94010.1 - 2.7e-06 27.2 0.0 0.00065 19.6 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme WD40 PF00400.32 EMC94012.1 - 3.8e-13 49.7 8.9 0.16 12.9 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Nop14 PF04147.12 EMC94012.1 - 0.024 12.9 15.1 0.032 12.5 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family ANAPC4_WD40 PF12894.7 EMC94012.1 - 0.058 13.7 0.0 28 5.1 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain YL1 PF05764.13 EMC94012.1 - 0.17 12.0 12.5 0.78 9.8 13.3 1.7 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 EMC94012.1 - 7.1 4.8 20.9 10 4.3 20.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BTB PF00651.31 EMC94013.1 - 1.6e-10 41.2 0.1 1.4e-09 38.2 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain Acetyltransf_4 PF13420.7 EMC94014.1 - 5.6e-14 52.6 0.0 6.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC94014.1 - 0.00025 21.3 0.0 0.00035 20.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMC94014.1 - 0.0006 19.7 0.0 0.002 18.0 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EMC94014.1 - 0.0007 20.0 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC94014.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain BTB PF00651.31 EMC94015.1 - 3.9e-08 33.5 0.0 1.6e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain PUL PF08324.11 EMC94016.1 - 9.7e-43 146.4 3.6 1.2e-42 146.0 3.6 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EMC94016.1 - 7.5e-41 138.9 0.0 1.3e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EMC94016.1 - 2.3e-30 104.2 17.6 1.5e-06 28.8 0.2 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC94016.1 - 0.0015 18.8 0.1 0.25 11.7 0.0 3.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC94016.1 - 0.048 12.3 0.2 2.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 BTB PF00651.31 EMC94017.1 - 2.5e-09 37.3 0.0 3.3e-08 33.7 0.0 2.5 3 0 0 3 3 3 1 BTB/POZ domain Acetyltransf_2 PF00797.17 EMC94018.1 - 6.1e-42 144.1 0.6 1e-38 133.5 0.1 2.1 2 0 0 2 2 2 2 N-acetyltransferase Peptidase_C71 PF12386.8 EMC94018.1 - 0.06 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei DUF3782 PF12644.7 EMC94018.1 - 0.1 12.8 0.3 0.19 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) AMP-binding PF00501.28 EMC94019.1 - 1.4e-79 267.7 0.1 1.7e-79 267.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC94019.1 - 2.5e-16 60.4 0.3 5e-16 59.4 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DuffyBP_N PF12377.8 EMC94019.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Duffy binding protein N terminal 7TM_GPCR_Srv PF10323.9 EMC94019.1 - 0.17 11.2 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv IBR PF01485.21 EMC94020.1 - 6.9e-16 58.2 34.9 4.3e-09 36.5 2.8 4.5 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain DGOK PF05035.12 EMC94020.1 - 0.015 14.2 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase DUF1682 PF07946.14 EMC94021.1 - 7.3e-111 370.5 0.0 8.7e-111 370.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DAO PF01266.24 EMC94022.1 - 3e-44 152.0 0.2 3.8e-44 151.7 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMC94022.1 - 0.00084 19.4 0.1 0.022 14.7 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EMC94022.1 - 0.051 12.8 0.3 0.099 11.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 EMC94022.1 - 0.06 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 EMC94023.1 - 3.8e-14 52.9 9.8 0.039 14.9 0.1 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC94023.1 - 2.5e-05 24.5 0.0 2.4 8.5 0.0 5.0 3 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 EMC94024.1 - 8.2e-12 45.7 7.4 1.7e-09 38.1 0.5 2.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Mid2 PF04478.12 EMC94025.1 - 0.84 9.5 6.0 2.4 8.0 6.0 1.8 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor C1_4 PF07975.12 EMC94029.1 - 0.66 10.3 8.4 1.5 9.2 0.2 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-B_box PF00643.24 EMC94029.1 - 1.2 9.4 8.4 3.5 7.8 6.4 2.2 1 1 1 2 2 2 0 B-box zinc finger Isochorismatase PF00857.20 EMC94033.1 - 3.2e-43 147.9 0.1 8.5e-43 146.5 0.0 1.6 1 1 1 2 2 2 1 Isochorismatase family SRR1 PF07985.12 EMC94034.1 - 1.4e-12 47.4 0.1 4.4e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 SRR1 CDC37_N PF03234.14 EMC94035.1 - 1.9e-48 164.6 1.1 1.9e-48 164.6 1.1 2.8 4 1 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EMC94035.1 - 3.3e-40 136.7 0.7 7.8e-40 135.5 0.7 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EMC94035.1 - 2.1e-30 104.8 1.3 5.7e-30 103.4 0.4 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain Rab15_effector PF15208.6 EMC94035.1 - 0.0056 16.0 0.2 0.25 10.6 0.1 2.2 2 0 0 2 2 2 1 Rab15 effector DUF4269 PF14091.6 EMC94035.1 - 0.13 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) DUF4407 PF14362.6 EMC94035.1 - 0.62 9.4 10.2 0.36 10.1 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Adeno_E1B_55K_N PF04623.12 EMC94035.1 - 1.4 9.6 5.1 0.31 11.7 1.1 2.0 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus NOB1_Zn_bind PF08772.11 EMC94036.1 - 3.1e-33 113.7 3.0 5.3e-33 113.0 3.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EMC94036.1 - 1.7e-30 105.4 0.0 2.9e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease WRNPLPNID PF15017.6 EMC94036.1 - 0.0046 17.8 0.5 0.0046 17.8 0.5 1.9 2 0 0 2 2 2 1 Putative WW-binding domain and destruction box zf-NADH-PPase PF09297.11 EMC94036.1 - 0.029 14.0 3.5 0.042 13.5 1.0 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 EMC94036.1 - 0.056 13.5 0.1 0.17 11.9 0.3 1.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EMC94036.1 - 0.067 13.2 1.1 0.12 12.4 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EMC94036.1 - 0.16 12.1 3.0 0.22 11.7 1.3 2.1 2 0 0 2 2 2 0 Zinc ribbon domain PH PF00169.29 EMC94038.1 - 0.00016 22.1 0.1 0.00032 21.2 0.1 1.4 1 0 0 1 1 1 1 PH domain MFS_1 PF07690.16 EMC94039.1 - 1.7e-13 50.2 13.2 1.7e-13 50.2 13.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC94039.1 - 2.9e-07 29.7 0.2 2.9e-07 29.7 0.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter ELH PF02323.15 EMC94039.1 - 0.023 14.1 0.4 0.023 14.1 0.4 1.8 2 0 0 2 2 2 0 Egg-laying hormone precursor NDK PF00334.19 EMC94040.1 - 2.6e-54 182.9 0.0 2.9e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 EMC94041.1 - 8.1e-139 463.6 4.2 1.2e-138 463.1 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EMC94041.1 - 6.3e-25 87.3 0.4 2.9e-23 82.0 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EMC94041.1 - 7.4e-08 32.5 0.1 5.4e-07 29.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) PIRT PF15099.6 EMC94042.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Phage_Gp23 PF10669.9 EMC94042.1 - 0.024 14.9 1.6 0.041 14.2 1.6 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Vpu PF00558.19 EMC94042.1 - 0.051 13.3 0.6 0.074 12.8 0.6 1.2 1 0 0 1 1 1 0 Vpu protein G0-G1_switch_2 PF15103.6 EMC94042.1 - 0.086 13.3 0.3 0.14 12.6 0.3 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 MAP17 PF15807.5 EMC94042.1 - 1.1 9.5 4.6 0.36 11.1 1.8 1.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Presenilin PF01080.17 EMC94042.1 - 2 7.1 2.9 2 7.1 2.9 1.2 1 0 0 1 1 1 0 Presenilin Lig_C PF18330.1 EMC94046.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Rossmann-like PF10727.9 EMC94048.1 - 0.13 12.1 0.1 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Rossmann-like domain Sugar_tr PF00083.24 EMC94049.1 - 2.9e-83 280.2 26.2 5e-62 210.2 4.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMC94049.1 - 6e-14 51.7 33.8 8.3e-09 34.8 13.0 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily F-box-like PF12937.7 EMC94050.1 - 1.5e-05 24.7 0.1 4.6e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC94050.1 - 0.0058 16.5 1.1 0.019 14.8 0.0 2.3 3 0 0 3 3 3 1 F-box domain AmpE PF17113.5 EMC94051.1 - 0.14 11.4 0.6 0.15 11.3 0.6 1.1 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE DDOST_48kD PF03345.14 EMC94052.1 - 7.4e-164 545.5 0.0 8.5e-164 545.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4763 PF15960.5 EMC94053.1 - 0.0088 15.4 5.5 0.014 14.7 5.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) LMBR1 PF04791.16 EMC94053.1 - 0.17 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM70 PF14967.6 EMC94053.1 - 4.5 6.7 4.9 6.7 6.1 4.9 1.3 1 0 0 1 1 1 0 FAM70 protein ATG16 PF08614.11 EMC94054.1 - 0.087 13.0 7.4 0.12 12.6 7.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1204 PF06721.11 EMC94054.1 - 0.54 9.7 4.8 0.34 10.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) EF-1_beta_acid PF10587.9 EMC94054.1 - 4.7 7.8 8.2 18 5.9 1.9 2.5 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Asp PF00026.23 EMC94055.1 - 2.7e-59 201.2 1.5 4.7e-59 200.3 1.5 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMC94055.1 - 9.7e-13 48.7 0.5 7.8e-08 32.7 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMC94055.1 - 0.00094 19.8 1.6 0.13 12.9 0.3 3.9 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 EMC94055.1 - 0.068 12.9 0.0 0.51 10.1 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EMC94055.1 - 0.51 10.9 2.8 29 5.3 0.1 3.7 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease ABC_membrane PF00664.23 EMC94056.1 - 1.2e-51 176.0 16.0 1.5e-51 175.7 16.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMC94056.1 - 1.2e-34 119.8 0.0 4.2e-34 118.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EMC94056.1 - 0.00029 20.4 0.0 0.00078 18.9 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMC94056.1 - 0.00075 19.9 0.0 0.0031 17.9 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMC94056.1 - 0.0017 18.6 0.2 0.024 14.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EMC94056.1 - 0.0027 17.5 0.1 0.052 13.3 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EMC94056.1 - 0.01 15.6 0.1 0.04 13.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EMC94056.1 - 0.014 15.8 0.1 0.18 12.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EMC94056.1 - 0.023 14.3 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EMC94056.1 - 0.075 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 EMC94056.1 - 0.081 13.0 0.1 0.29 11.2 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 EMC94056.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EMC94056.1 - 0.13 12.5 0.8 1.5 9.1 0.8 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PrgI PF12666.7 EMC94056.1 - 0.23 12.2 4.5 2.9 8.7 0.1 3.0 3 0 0 3 3 3 0 PrgI family protein Phage_holin_3_5 PF16085.5 EMC94056.1 - 1.8 8.7 6.1 0.51 10.5 0.9 2.5 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III Clathrin_lg_ch PF01086.17 EMC94057.1 - 7e-78 261.8 9.0 7.9e-78 261.7 9.0 1.0 1 0 0 1 1 1 1 Clathrin light chain CTD_bind PF04818.13 EMC94058.1 - 1.9e-18 67.0 0.0 3.7e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. MCD_N PF17408.2 EMC94058.1 - 0.066 13.3 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain Innate_immun PF12782.7 EMC94058.1 - 0.14 11.7 2.1 0.21 11.1 0.4 1.8 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family DUF4267 PF14087.6 EMC94060.1 - 1e-24 86.7 2.0 1.3e-24 86.4 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Lyase_1 PF00206.20 EMC94061.1 - 3.9e-25 88.9 0.0 7.9e-25 87.9 0.0 1.4 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 EMC94061.1 - 3e-17 62.9 0.0 9.2e-17 61.4 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus SwrA PF17423.2 EMC94061.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Swarming motility protein AA_permease PF00324.21 EMC94062.1 - 3.7e-129 431.4 41.7 4.6e-129 431.1 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMC94062.1 - 8.6e-41 140.2 42.2 1.3e-40 139.6 42.2 1.3 1 0 0 1 1 1 1 Amino acid permease CNH PF00780.22 EMC94063.1 - 6.1e-68 229.4 0.0 9.3e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EMC94063.1 - 3.9e-31 108.7 0.1 7.7e-31 107.7 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EMC94063.1 - 1.9e-13 50.7 0.0 8e-12 45.4 0.0 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EMC94063.1 - 0.041 14.4 0.1 0.25 11.9 0.0 2.3 2 0 0 2 2 2 0 PH domain PH_13 PF16652.5 EMC94063.1 - 0.055 13.3 0.0 2.7 7.8 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain FMO-like PF00743.19 EMC94065.1 - 1.5e-16 60.0 0.3 2.2e-15 56.1 0.2 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMC94065.1 - 6.6e-07 28.8 0.0 1e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC94065.1 - 7.2e-06 26.1 0.1 4.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMC94065.1 - 1.7e-05 24.2 0.1 0.00014 21.3 0.0 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC94065.1 - 5.1e-05 22.6 0.0 0.012 14.8 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMC94065.1 - 0.017 15.1 0.3 1.1 9.2 0.0 2.7 3 1 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 EMC94065.1 - 0.072 12.3 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Thi4 family adh_short PF00106.25 EMC94066.1 - 7.3e-19 68.0 0.1 3.9e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMC94066.1 - 4.9e-10 39.6 0.0 7.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMC94066.1 - 5.8e-10 39.1 0.0 9.9e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMC94066.1 - 0.0089 15.5 0.1 0.019 14.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC94066.1 - 0.05 12.7 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Mito_carr PF00153.27 EMC94067.1 - 3.1e-46 155.2 0.0 2.4e-15 56.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ApoLp-III PF07464.11 EMC94067.1 - 0.3 11.2 10.8 0.2 11.7 3.1 2.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 EMC94067.1 - 1.2 9.8 21.4 3.6 8.3 0.4 4.4 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) PPR_2 PF13041.6 EMC94070.1 - 0.061 13.5 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 PPR repeat family Pyridox_ox_2 PF12900.7 EMC94071.1 - 6.4e-32 110.5 0.0 8.4e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1769 PF08588.10 EMC94072.1 - 5.2e-26 90.6 2.2 7.1e-26 90.2 0.2 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1769) Annexin PF00191.20 EMC94073.1 - 8e-72 237.3 8.0 9.2e-18 64.1 0.2 4.1 4 0 0 4 4 4 4 Annexin DUF515 PF04415.12 EMC94073.1 - 0.0057 15.1 0.1 0.037 12.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF515) Acetyltransf_11 PF13720.6 EMC94073.1 - 0.011 16.2 0.6 8.8 6.9 0.0 3.4 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF5638 PF18688.1 EMC94073.1 - 0.034 14.4 0.9 1.6 9.1 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5638) YlbE PF14003.6 EMC94073.1 - 0.077 13.4 1.1 28 5.2 0.0 3.3 3 0 0 3 3 3 0 YlbE-like protein Presenilin PF01080.17 EMC94075.1 - 0.45 9.2 1.1 0.54 9.0 1.1 1.1 1 0 0 1 1 1 0 Presenilin Spem1 PF15670.5 EMC94075.1 - 0.6 9.6 5.7 0.88 9.1 5.7 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 NPR3 PF03666.13 EMC94075.1 - 1.4 7.6 3.9 1.8 7.3 3.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Aa_trans PF01490.18 EMC94077.1 - 1.8e-96 323.4 12.2 2.9e-96 322.7 12.2 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EMC94077.1 - 0.00074 18.7 19.5 0.00074 18.7 19.5 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Abhydrolase_9_N PF15420.6 EMC94077.1 - 0.066 13.2 0.2 0.066 13.2 0.2 3.8 4 1 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus Dynactin_p22 PF07426.11 EMC94078.1 - 6.6e-06 26.1 0.0 8.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 M157 PF11624.8 EMC94078.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 FAD_binding_3 PF01494.19 EMC94079.1 - 1.1e-81 274.8 0.0 1.4e-81 274.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMC94079.1 - 2.4e-45 154.6 0.0 4.7e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EMC94079.1 - 0.00058 18.7 0.0 0.00085 18.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 EMC94079.1 - 0.0047 16.0 0.0 0.036 13.1 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EMC94079.1 - 0.0057 15.9 0.0 0.027 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC94079.1 - 0.013 15.8 0.1 0.036 14.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMC94079.1 - 0.044 12.8 0.1 0.068 12.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMC94079.1 - 0.072 12.1 0.2 0.34 9.9 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 EMC94079.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_33 PF10017.9 EMC94080.1 - 6.6e-90 301.4 0.0 7.7e-90 301.2 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Zn_clus PF00172.18 EMC94082.1 - 3.9e-08 33.3 9.0 7.8e-08 32.3 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC94082.1 - 0.00022 20.3 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 EMC94083.1 - 2.2e-20 73.4 0.0 7e-20 71.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EMC94083.1 - 3.5e-20 71.3 0.1 7.3e-20 70.3 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EMC94083.1 - 0.00014 21.3 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EMC94083.1 - 0.014 15.1 0.0 0.27 10.9 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EMC94083.1 - 0.09 12.6 0.1 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.9 EMC94084.1 - 1.9e-28 98.5 1.7 2.2e-28 98.4 1.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EMC94084.1 - 0.15 12.1 3.3 4.5 7.4 0.1 2.8 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TRAM_LAG1_CLN8 PF03798.16 EMC94087.1 - 6.8e-37 127.1 15.8 6.8e-37 127.1 15.8 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EMC94087.1 - 9.2e-18 63.7 0.4 4.1e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 TRAM1-like protein DLIC PF05783.11 EMC94088.1 - 2.7e-08 33.1 7.7 0.0022 16.9 0.0 4.0 5 0 0 5 5 5 3 Dynein light intermediate chain (DLIC) Hpt PF01627.23 EMC94088.1 - 0.065 13.5 0.3 0.2 12.0 0.3 1.8 1 0 0 1 1 1 0 Hpt domain NUDIX_2 PF13869.6 EMC94090.1 - 4.1e-79 264.6 0.0 4.8e-79 264.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Zn_clus PF00172.18 EMC94093.1 - 9.4e-11 41.7 10.4 1.5e-10 41.0 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC94093.1 - 1.2e-08 34.3 0.0 1.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EMC94094.1 - 1.5e-37 128.9 0.0 2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC94094.1 - 2.6e-28 99.2 0.0 3.3e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC94094.1 - 5e-16 59.1 0.3 7.5e-16 58.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC94094.1 - 3.4e-11 43.1 0.1 4.9e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC94094.1 - 1.3e-07 31.4 0.4 3.7e-07 29.9 0.4 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMC94094.1 - 3.5e-06 27.0 0.1 7.1e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMC94094.1 - 0.0015 17.7 0.0 0.0026 17.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein YAcAr PF10686.9 EMC94094.1 - 0.014 15.4 2.0 17 5.4 0.1 4.1 4 2 1 5 5 5 0 YspA, cpYpsA-related SLOG family NmrA PF05368.13 EMC94094.1 - 0.031 13.8 0.3 0.36 10.4 0.2 2.0 2 0 0 2 2 2 0 NmrA-like family ATP-grasp_5 PF13549.6 EMC94094.1 - 0.061 12.8 0.1 0.096 12.1 0.1 1.2 1 0 0 1 1 1 0 ATP-grasp domain YjeF_N PF03853.15 EMC94094.1 - 0.085 12.7 0.1 0.34 10.8 0.2 1.9 2 1 1 3 3 3 0 YjeF-related protein N-terminus Eno-Rase_NADH_b PF12242.8 EMC94094.1 - 0.23 11.2 0.6 0.74 9.6 0.3 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DJ-1_PfpI PF01965.24 EMC94095.1 - 1.4e-16 60.7 0.1 2.3e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMC94095.1 - 4.9e-05 23.1 0.0 6.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like MOFRL PF05161.13 EMC94095.1 - 0.095 12.9 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 MOFRL family p450 PF00067.22 EMC94098.1 - 5.5e-39 134.2 0.0 7e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3322 PF11795.8 EMC94098.1 - 0.021 14.8 0.2 0.054 13.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) CTD_bind PF04818.13 EMC94100.1 - 0.049 14.5 0.0 0.11 13.3 0.0 1.7 1 1 0 1 1 1 0 RNA polymerase II-binding domain. Rep_2 PF01719.17 EMC94100.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Plasmid replication protein Hid1 PF12722.7 EMC94101.1 - 2.1e-202 674.5 0.0 5.2e-202 673.2 0.0 1.6 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EMC94101.1 - 1.1e-82 278.4 0.0 1.3e-82 278.2 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Peptidase_M16_M PF16187.5 EMC94102.1 - 2.7e-95 318.9 0.5 4.3e-95 318.2 0.5 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EMC94102.1 - 3.8e-33 114.6 2.5 9.1e-32 110.1 1.4 3.3 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMC94102.1 - 1.7e-31 109.6 0.4 2.7e-19 69.9 0.0 3.6 4 0 0 4 4 4 2 Peptidase M16 inactive domain DUF4525 PF15027.6 EMC94102.1 - 0.039 13.7 0.1 10 5.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF937 PF06078.11 EMC94102.1 - 0.58 10.8 3.4 1.6 9.3 3.4 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) BNR_2 PF13088.6 EMC94103.1 - 7.9e-06 25.4 0.0 5.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 EMC94103.1 - 0.0018 17.2 0.0 0.24 10.2 0.0 2.7 4 0 0 4 4 4 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 EMC94103.1 - 0.0083 16.0 9.3 0.34 11.1 0.6 3.9 3 0 0 3 3 3 2 BNR/Asp-box repeat F5_F8_type_C PF00754.25 EMC94103.1 - 0.025 14.7 0.1 44 4.2 0.0 3.5 4 0 0 4 4 4 0 F5/8 type C domain 3HCDH_N PF02737.18 EMC94104.1 - 0.014 15.3 4.3 0.045 13.6 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3585 PF12130.8 EMC94104.1 - 0.047 13.8 12.3 2.1 8.5 11.4 2.3 1 1 1 2 2 2 0 Bivalent Mical/EHBP Rab binding domain DUF3086 PF11285.8 EMC94104.1 - 0.26 10.4 8.9 0.34 10.0 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Oxysterol_BP PF01237.18 EMC94104.1 - 4.8 5.9 11.7 1.1 8.0 7.9 1.7 2 0 0 2 2 2 0 Oxysterol-binding protein TMPIT PF07851.13 EMC94104.1 - 8.9 5.5 8.9 13 4.9 8.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Sugar_tr PF00083.24 EMC94105.1 - 4.9e-102 342.1 16.5 5.6e-102 341.9 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC94105.1 - 1.4e-26 93.2 29.2 2.1e-25 89.4 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MatC_N PF07158.11 EMC94105.1 - 0.012 15.6 3.6 0.012 15.6 3.6 2.1 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Alpha-L-AF_C PF06964.12 EMC94106.1 - 2.1e-30 106.1 0.6 3.2e-30 105.5 0.6 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 EMC94106.1 - 0.032 14.1 0.5 0.1 12.5 0.5 1.8 1 1 0 1 1 1 0 Glycoside hydrolase family 44 Glyco_hydro_30C PF17189.4 EMC94106.1 - 0.16 12.2 0.1 0.42 10.8 0.1 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain FAD_binding_1 PF00667.20 EMC94107.1 - 7.8e-51 172.8 0.0 3.2e-50 170.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 EMC94107.1 - 1.5e-10 41.7 0.0 3.6e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cupin_2 PF07883.11 EMC94108.1 - 2e-11 43.4 0.8 2e-11 43.4 0.8 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EMC94108.1 - 4.4e-07 29.6 0.0 6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EMC94108.1 - 0.0023 17.9 0.2 0.0023 17.9 0.2 1.8 2 0 0 2 2 2 1 AraC-like ligand binding domain JmjC PF02373.22 EMC94108.1 - 0.023 15.1 0.1 0.11 12.9 0.1 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase DMSP_lyase PF16867.5 EMC94108.1 - 0.025 14.2 0.4 0.037 13.7 0.4 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase FdtA PF05523.11 EMC94108.1 - 0.036 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal GPI PF06560.11 EMC94108.1 - 0.053 12.8 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) OPT PF03169.15 EMC94110.1 - 1.3e-154 516.2 45.9 1.5e-154 516.0 45.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GST_N_2 PF13409.6 EMC94111.1 - 1.5e-14 54.0 0.0 4.7e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMC94111.1 - 4.8e-10 39.3 0.0 5.4e-09 36.0 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMC94111.1 - 0.00074 19.7 0.0 0.0023 18.1 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMC94111.1 - 0.14 12.5 0.0 8.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DHHA2 PF02833.14 EMC94113.1 - 2.4e-34 118.6 0.0 4.3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EMC94113.1 - 8.8e-10 38.7 0.0 2.3e-09 37.4 0.0 1.7 1 1 1 2 2 2 1 DHH family SGS PF05002.15 EMC94114.1 - 7.2e-34 115.8 3.4 1.9e-33 114.4 3.4 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EMC94114.1 - 3.2e-12 47.3 0.1 7.7e-12 46.1 0.1 1.6 2 0 0 2 2 1 1 CS domain TPR_2 PF07719.17 EMC94114.1 - 3.2e-09 36.2 4.5 0.061 13.5 0.2 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMC94114.1 - 1.6e-06 28.3 4.7 4.8e-06 26.8 1.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMC94114.1 - 5.4e-06 26.9 6.1 0.0046 17.6 6.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMC94114.1 - 3.9e-05 23.3 1.3 0.3 11.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMC94114.1 - 0.0013 19.2 0.1 0.03 14.8 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EMC94114.1 - 0.013 15.7 0.9 0.029 14.5 0.9 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMC94114.1 - 0.013 15.9 0.0 0.053 13.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMC94114.1 - 0.022 14.5 0.0 0.12 12.0 0.0 2.3 1 1 1 2 2 2 0 TPR repeat ANAPC3 PF12895.7 EMC94114.1 - 0.024 14.8 0.5 0.071 13.3 0.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Med3 PF11593.8 EMC94114.1 - 0.028 13.6 5.2 0.034 13.4 0.2 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal TPR_10 PF13374.6 EMC94114.1 - 0.27 11.2 0.9 1.1 9.3 0.9 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat UQ_con PF00179.26 EMC94115.1 - 2.5e-51 173.0 0.0 2.9e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PAAR_motif PF05488.13 EMC94116.1 - 0.13 12.5 0.4 0.28 11.4 0.4 1.6 1 0 0 1 1 1 0 PAAR motif Glyco_hydro_28 PF00295.17 EMC94119.1 - 8.6e-18 64.5 6.7 1.2e-17 64.0 6.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EMC94119.1 - 5.9e-08 32.8 19.1 6.6e-07 29.4 0.4 3.2 1 1 2 3 3 3 2 Pectate lyase superfamily protein Gtr1_RagA PF04670.12 EMC94120.1 - 1.3e-88 296.2 0.1 1.8e-88 295.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EMC94120.1 - 2.1e-09 37.6 0.0 5.1e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EMC94120.1 - 6.9e-09 35.5 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EMC94120.1 - 7e-09 35.4 0.4 4.1e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMC94120.1 - 2.8e-07 30.6 0.0 7.8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 EMC94120.1 - 0.00046 19.5 4.3 0.1 11.8 0.1 3.0 2 1 1 3 3 3 2 G-protein alpha subunit DUF815 PF05673.13 EMC94120.1 - 0.0017 17.6 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EMC94120.1 - 0.0019 18.2 0.4 0.12 12.3 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 EMC94120.1 - 0.0057 17.2 0.2 0.017 15.6 0.1 2.0 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EMC94120.1 - 0.018 14.8 1.1 0.19 11.5 0.1 2.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_10 PF12846.7 EMC94120.1 - 0.083 11.8 0.1 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain DUF3697 PF12478.8 EMC94120.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 Fungal_trans PF04082.18 EMC94122.1 - 4.4e-13 48.9 0.0 8.8e-13 47.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC94122.1 - 0.00024 21.1 10.4 0.00061 19.9 10.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1e PF01406.19 EMC94126.1 - 2.2e-111 372.1 0.1 3.4e-111 371.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EMC94126.1 - 7e-05 21.7 0.2 0.18 10.6 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) 40S_SA_C PF16122.5 EMC94126.1 - 0.23 12.8 5.6 0.71 11.3 5.6 1.9 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus HTH_21 PF13276.6 EMC94127.1 - 0.042 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 HTH-like domain DUF4748 PF15932.5 EMC94128.1 - 2.3e-18 65.7 0.9 2.3e-18 65.7 0.9 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4748) ERCC3_RAD25_C PF16203.5 EMC94129.1 - 8.5e-121 401.8 0.5 1.8e-120 400.7 0.5 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EMC94129.1 - 1.5e-32 112.4 0.0 3.2e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC94129.1 - 2.1e-16 60.4 0.1 6.4e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMC94129.1 - 7.9e-11 42.3 0.2 3.2e-10 40.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EMC94129.1 - 1.2e-06 27.5 0.1 1.8e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EMC94129.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Elf4 PF07011.11 EMC94129.1 - 0.069 13.1 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Early Flowering 4 domain CAF1A PF12253.8 EMC94130.1 - 2e-19 69.6 2.4 2e-19 69.6 2.4 3.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A BUD22 PF09073.10 EMC94130.1 - 0.051 12.9 22.0 0.15 11.4 15.9 2.1 2 0 0 2 2 2 0 BUD22 Tuberculin PF12198.8 EMC94130.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Theoretical tuberculin protein DUF5423 PF17461.2 EMC94130.1 - 1.3 7.8 7.7 0.94 8.3 5.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5423) RR_TM4-6 PF06459.12 EMC94130.1 - 1.4 8.7 18.3 2.9 7.6 18.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 EMC94130.1 - 1.8 7.7 4.9 2.8 7.1 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EMC94130.1 - 4.2 6.0 10.5 6.1 5.5 10.5 1.2 1 0 0 1 1 1 0 Presenilin DUF3292 PF11696.8 EMC94130.1 - 5.1 5.4 10.7 8.5 4.6 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Borrelia_P83 PF05262.11 EMC94130.1 - 9.6 4.6 18.2 14 4.0 18.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TP6A_N PF04406.14 EMC94131.1 - 2e-24 85.4 0.0 3.6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Fungal_trans PF04082.18 EMC94132.1 - 5e-14 52.0 0.0 8.3e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EMC94132.1 - 2.6e-10 40.2 7.9 0.00017 21.9 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC94132.1 - 1.7e-08 34.5 1.2 1.7e-08 34.5 1.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC94132.1 - 2.1e-06 28.1 7.0 0.023 15.5 2.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 EMC94132.1 - 4.8e-06 26.6 6.8 4.8e-06 26.6 6.8 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zf_RING PF16744.5 EMC94132.1 - 0.24 11.5 4.4 0.13 12.4 1.8 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger DUF3759 PF12585.8 EMC94133.1 - 4.7e-40 135.5 5.1 6e-40 135.2 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Serine_protease PF18405.1 EMC94133.1 - 0.00075 18.7 0.0 0.00088 18.5 0.0 1.1 1 0 0 1 1 1 1 Gammaproteobacterial serine protease DUF3824 PF12868.7 EMC94133.1 - 0.049 14.3 3.8 0.13 12.9 3.8 1.8 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Abhydrolase_2 PF02230.16 EMC94134.1 - 2.2e-24 86.5 0.0 2.6e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EMC94134.1 - 0.00083 20.0 0.0 0.00098 19.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EMC94134.1 - 0.0059 16.2 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 EMC94134.1 - 0.031 14.0 0.2 0.17 11.6 0.1 2.1 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EMC94134.1 - 0.18 11.0 0.1 3.6 6.8 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Pkinase PF00069.25 EMC94136.1 - 2.8e-69 233.4 0.0 3.8e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC94136.1 - 2.6e-47 161.3 0.0 5.7e-47 160.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC94136.1 - 4.6e-05 22.9 0.0 0.0008 18.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMC94136.1 - 7e-05 21.8 0.8 0.00013 20.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase SesA PF17107.5 EMC94136.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases APH PF01636.23 EMC94136.1 - 0.048 13.6 0.0 4 7.3 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family IF4E PF01652.18 EMC94137.1 - 7.2e-56 188.4 0.3 1.2e-55 187.7 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 EMC94138.1 - 4.9e-36 124.6 0.0 9.3e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SEF14_adhesin PF06443.11 EMC94138.1 - 0.0089 15.9 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 1 SEF14-like adhesin GGACT PF06094.12 EMC94139.1 - 9.8e-21 74.6 0.0 1.6e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like PQ-loop PF04193.14 EMC94140.1 - 2.1e-23 81.9 5.5 5.2e-15 54.9 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EMC94140.1 - 0.05 14.4 5.1 0.06 14.2 3.6 1.8 1 1 1 2 2 2 0 ER lumen protein retaining receptor DAD PF02109.16 EMC94140.1 - 0.07 13.4 2.4 0.8 10.0 0.2 2.7 3 0 0 3 3 3 0 DAD family ERM PF00769.19 EMC94141.1 - 2.5e-06 27.5 5.5 3.4e-06 27.1 5.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family G-gamma PF00631.22 EMC94141.1 - 0.026 14.5 0.1 0.073 13.1 0.1 1.7 1 0 0 1 1 1 0 GGL domain DUF4517 PF15006.6 EMC94141.1 - 0.051 13.7 0.8 0.078 13.1 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4517) DUF3450 PF11932.8 EMC94141.1 - 0.11 11.8 8.6 0.16 11.2 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.17 EMC94141.1 - 1.2 9.7 19.4 6 7.5 19.4 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor Hap4_Hap_bind PF10297.9 EMC94141.1 - 3 8.1 5.1 5.7 7.2 5.1 1.5 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Seryl_tRNA_N PF02403.22 EMC94141.1 - 3.3 8.0 12.0 5 7.4 12.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.21 EMC94141.1 - 7.9 6.7 18.0 31 4.8 18.0 1.8 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 EMC94141.1 - 8.6 6.5 17.2 0.62 10.2 11.3 1.9 1 1 1 2 2 2 0 Basic region leucine zipper UPF0047 PF01894.17 EMC94142.1 - 8e-37 125.9 0.0 1e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 PhoD PF09423.10 EMC94145.1 - 3.2e-42 144.8 0.0 6.6e-42 143.8 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase WRW PF10206.9 EMC94147.1 - 0.034 14.5 1.3 0.072 13.5 1.3 1.6 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f FAP PF07174.11 EMC94147.1 - 0.041 13.3 6.5 0.055 12.9 6.5 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) tRNA-synt_1c PF00749.21 EMC94148.1 - 2.4e-109 365.0 0.3 3.2e-109 364.7 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EMC94148.1 - 3.6e-34 118.1 0.9 2.3e-33 115.5 0.9 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 EMC94148.1 - 0.016 14.6 0.1 0.035 13.4 0.1 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_3 PF14497.6 EMC94148.1 - 0.082 13.1 0.1 0.99 9.6 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain USP7_ICP0_bdg PF12436.8 EMC94149.1 - 7.5e-84 280.8 0.0 7.3e-81 271.0 0.0 2.3 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EMC94149.1 - 4.9e-64 215.8 0.0 9.4e-64 214.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EMC94149.1 - 6.3e-44 150.4 0.2 9.1e-44 149.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC94149.1 - 7.3e-17 61.9 0.0 3.3e-16 59.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EMC94149.1 - 4.8e-07 29.9 0.0 1.4e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 MATH domain BCDHK_Adom3 PF10436.9 EMC94150.1 - 1.5e-46 158.2 0.1 2.5e-46 157.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EMC94150.1 - 2.6e-07 31.1 0.0 5.7e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fructosamin_kin PF03881.14 EMC94150.1 - 0.026 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Pmp3 PF01679.17 EMC94152.1 - 1.3e-14 54.1 1.7 1.3e-14 54.1 1.7 1.8 2 0 0 2 2 2 1 Proteolipid membrane potential modulator SPT_ssu-like PF11779.8 EMC94152.1 - 0.3 10.7 2.3 5.9 6.6 0.1 2.3 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like BTB PF00651.31 EMC94153.1 - 3.1e-08 33.8 0.0 4.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain GTP_cyclohydroI PF01227.22 EMC94157.1 - 1.9e-73 245.7 0.2 2.7e-73 245.2 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EMC94157.1 - 0.0082 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein SLATT_fungal PF18142.1 EMC94157.1 - 0.12 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Pkinase PF00069.25 EMC94158.1 - 4.5e-71 239.3 0.0 6.5e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC94158.1 - 8.8e-35 120.2 0.0 1.7e-34 119.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMC94158.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMC94158.1 - 0.0011 18.3 0.1 0.0025 17.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EMC94158.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EMC94158.1 - 0.0024 16.9 0.0 0.039 12.9 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EMC94158.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EMC94158.1 - 0.041 13.8 0.2 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Transglut_core PF01841.19 EMC94159.1 - 1.6e-09 38.2 0.9 4e-09 36.9 0.9 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EMC94159.1 - 4.1e-07 29.6 0.0 1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMC94159.1 - 0.00019 21.0 0.1 0.00019 21.0 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EMC94159.1 - 0.052 13.4 0.7 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Variant SH3 domain SRP-alpha_N PF04086.13 EMC94159.1 - 4.1 7.2 10.4 4 7.3 3.9 2.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF3294 PF07957.11 EMC94160.1 - 0.00055 19.8 0.3 0.00063 19.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) BRF1 PF07741.13 EMC94160.1 - 2.5 8.5 7.0 3.8 7.9 4.9 2.0 1 1 1 2 2 2 0 Brf1-like TBP-binding domain Peptidase_M18 PF02127.15 EMC94161.1 - 1.1e-130 436.4 0.0 1.3e-130 436.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EMC94161.1 - 0.017 14.2 0.1 4.9 6.1 0.0 2.4 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase Peptidase_M23_N PF18421.1 EMC94162.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain Glyco_transf_21 PF13506.6 EMC94163.1 - 1.6e-15 57.0 0.4 6.5e-07 29.0 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EMC94163.1 - 2.7e-08 34.0 0.0 6.5e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMC94163.1 - 0.00086 19.1 0.0 0.0072 16.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Fez1 PF06818.15 EMC94164.1 - 3.3 8.1 45.7 0.028 14.9 18.3 3.2 1 1 2 3 3 3 0 Fez1 Fib_alpha PF08702.10 EMC94164.1 - 5.1 7.3 25.8 0.7 10.1 9.1 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Nop10p PF04135.12 EMC94166.1 - 3.2e-22 78.3 1.0 3.9e-22 78.0 1.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family His_Phos_1 PF00300.22 EMC94167.1 - 1.2e-17 64.2 0.0 1.7e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_transf_90 PF05686.12 EMC94169.1 - 7.9e-18 64.5 7.0 7.2e-15 54.8 0.1 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 tRNA-synt_1d PF00750.19 EMC94170.1 - 9.8e-100 333.9 7.5 2.5e-60 204.3 5.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 EMC94170.1 - 2.4e-24 85.8 4.2 2.8e-24 85.6 0.5 2.7 2 1 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EMC94170.1 - 0.00017 22.1 0.0 0.00048 20.6 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain TraF PF13728.6 EMC94170.1 - 0.21 11.4 7.9 0.2 11.5 6.1 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein DivIC PF04977.15 EMC94170.1 - 3.1 7.6 9.9 6.3 6.7 0.4 2.6 2 0 0 2 2 2 0 Septum formation initiator BRF1 PF07741.13 EMC94170.1 - 6.2 7.2 9.4 3.8 7.9 6.4 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SlyX PF04102.12 EMC94170.1 - 6.9 7.4 10.5 1.4 9.6 1.5 2.9 3 0 0 3 3 3 0 SlyX AZUL PF16558.5 EMC94172.1 - 0.15 12.3 0.5 0.67 10.2 0.5 2.1 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A NinG PF05766.12 EMC94173.1 - 0.065 13.2 1.5 0.16 11.9 1.5 1.6 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF4551 PF15087.6 EMC94173.1 - 3.5 6.4 11.0 4.4 6.0 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Abhydrolase_1 PF00561.20 EMC94174.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EMC94174.1 - 0.036 13.7 0.1 0.062 12.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase eIF-5_eIF-2B PF01873.17 EMC94175.1 - 0.19 11.6 0.0 0.94 9.4 0.0 1.9 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Fungal_trans PF04082.18 EMC94176.1 - 8.3e-16 57.8 0.0 1.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC94176.1 - 3e-07 30.4 11.4 6e-07 29.5 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 EMC94176.1 - 0.055 11.9 0.1 0.086 11.3 0.1 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Velvet PF11754.8 EMC94177.1 - 3.8e-05 23.7 0.9 0.0014 18.7 0.9 2.6 1 1 0 1 1 1 1 Velvet factor DUF3602 PF12223.8 EMC94177.1 - 0.089 13.4 3.6 0.12 13.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) Pkinase PF00069.25 EMC94181.1 - 1e-64 218.4 0.0 1.3e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC94181.1 - 9.3e-35 120.1 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMC94181.1 - 0.0001 22.3 0.0 0.019 14.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMC94181.1 - 0.00029 19.9 0.0 0.00038 19.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EMC94181.1 - 0.0086 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMC94181.1 - 0.023 14.0 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 EMC94181.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EMC94181.1 - 0.077 12.6 0.0 0.79 9.3 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AMP-binding PF00501.28 EMC94182.1 - 1.8e-95 320.0 0.0 2.2e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC94182.1 - 6.2e-20 72.0 0.1 1.4e-19 70.8 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.15 EMC94183.1 - 2.8e-13 50.3 0.0 7.3e-13 49.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4800 PF16057.5 EMC94184.1 - 0.048 12.9 0.2 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Fungal_trans PF04082.18 EMC94185.1 - 9.4e-08 31.4 0.0 2.5e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC94185.1 - 0.0012 18.9 5.6 0.0022 18.1 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_12 PF13087.6 EMC94186.1 - 2.1e-36 125.4 0.0 4.6e-36 124.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EMC94186.1 - 7.8e-27 94.7 0.3 5.9e-26 91.8 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMC94186.1 - 4e-09 37.0 0.0 8.3e-07 29.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EMC94186.1 - 2e-08 34.2 0.1 2.7e-06 27.2 0.0 2.8 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EMC94186.1 - 0.00084 19.1 0.0 0.9 9.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EMC94186.1 - 0.0013 18.7 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMC94186.1 - 0.0042 16.9 0.0 0.0092 15.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 EMC94186.1 - 0.0083 15.7 0.2 0.02 14.4 0.2 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EMC94186.1 - 0.049 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 EMC94186.1 - 0.061 13.6 0.0 1 9.6 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.14 EMC94186.1 - 0.096 12.7 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC94186.1 - 0.098 13.0 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain HeLo PF14479.6 EMC94187.1 - 2.2e-06 27.7 5.9 5.2e-05 23.2 0.1 3.2 3 0 0 3 3 3 2 Prion-inhibition and propagation adh_short_C2 PF13561.6 EMC94188.1 - 8.4e-55 185.9 0.2 2.6e-54 184.3 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC94188.1 - 6.1e-38 130.2 0.1 8.5e-38 129.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC94188.1 - 1e-11 45.1 0.2 1.5e-11 44.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC94188.1 - 0.0045 16.5 0.1 0.012 15.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC94188.1 - 0.0091 15.4 0.0 3.4 7.0 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase TPP_enzyme_C PF02775.21 EMC94189.1 - 0.056 13.2 0.2 0.1 12.4 0.2 1.5 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CbtA PF09490.10 EMC94190.1 - 0.49 10.1 3.3 0.88 9.3 3.3 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Helo_like_N PF17111.5 EMC94192.1 - 0.0063 15.9 0.2 0.0072 15.7 0.2 1.0 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF4149 PF13664.6 EMC94193.1 - 2.7e-15 56.5 2.1 4.5e-15 55.8 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) MFS_1 PF07690.16 EMC94196.1 - 1.3e-37 129.6 58.2 2.3e-37 128.7 55.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC94196.1 - 3.9e-12 45.4 22.6 5.2e-12 45.0 22.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nup88 PF10168.9 EMC94197.1 - 0.00021 19.2 0.6 0.011 13.6 0.0 2.6 3 0 0 3 3 3 2 Nuclear pore component WASH_WAHD PF11945.8 EMC94197.1 - 0.1 12.1 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 WAHD domain of WASH complex Spectrin PF00435.21 EMC94197.1 - 0.3 11.6 0.1 0.3 11.6 0.1 3.2 4 0 0 4 4 4 0 Spectrin repeat PspA_IM30 PF04012.12 EMC94197.1 - 6.2 6.3 7.9 3.2 7.3 0.3 2.6 1 1 0 2 2 2 0 PspA/IM30 family RRM_1 PF00076.22 EMC94198.1 - 7.6e-17 60.9 0.0 1.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ACPS PF01648.20 EMC94199.1 - 3.2e-07 30.5 0.0 3.1e-06 27.3 0.0 2.4 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.19 EMC94200.1 - 2.4e-55 187.3 0.0 6.2e-46 156.6 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EMC94200.1 - 1.9e-10 40.6 0.0 6e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EMC94200.1 - 0.00019 21.3 0.0 0.076 12.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 EMC94200.1 - 0.0039 16.9 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EMC94200.1 - 0.0084 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family PAN_4 PF14295.6 EMC94201.1 - 0.022 14.6 1.0 0.36 10.8 0.2 2.6 2 0 0 2 2 2 0 PAN domain RTC PF01137.21 EMC94203.1 - 4.5e-58 196.1 0.0 6.6e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PEP_mutase PF13714.6 EMC94204.1 - 1.8e-54 184.7 0.6 2.1e-54 184.5 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase SSF PF00474.17 EMC94205.1 - 3.5e-21 75.5 28.1 5.4e-21 74.9 28.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Oxidored_FMN PF00724.20 EMC94206.1 - 5.7e-96 321.7 0.0 6.6e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 2OG-FeII_Oxy PF03171.20 EMC94208.1 - 1.4e-11 44.8 0.0 2.9e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMC94208.1 - 5.3e-07 30.4 0.0 1.6e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal eIF-5a PF01287.20 EMC94209.1 - 6.6e-08 32.5 0.1 9.7e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold CNH PF00780.22 EMC94211.1 - 9.7e-69 232.0 0.0 3e-68 230.4 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EMC94211.1 - 1e-42 145.4 0.0 2.4e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EMC94211.1 - 2.5e-38 132.2 0.0 4.7e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EMC94211.1 - 3.2e-14 52.7 0.0 7.9e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 EMC94211.1 - 0.12 12.2 0.5 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain ATP-synt_C PF00137.21 EMC94212.1 - 3.5e-29 100.9 35.8 2.3e-18 66.3 12.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ank_2 PF12796.7 EMC94213.1 - 3.5e-09 37.1 1.4 0.00044 20.8 0.8 3.5 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 EMC94213.1 - 1.3e-08 34.9 2.9 0.51 10.9 0.5 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EMC94213.1 - 2.5e-05 24.4 2.7 0.035 14.4 0.2 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) 3HCDH_RFF PF18321.1 EMC94213.1 - 0.38 11.2 3.0 0.87 10.1 0.3 2.8 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain PhoD PF09423.10 EMC94214.1 - 1.3e-110 369.7 7.9 1.8e-110 369.3 7.9 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EMC94214.1 - 7.7e-31 106.5 0.3 6.3e-30 103.6 0.2 2.4 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EMC94214.1 - 7.9e-05 23.2 2.4 0.006 17.1 0.3 3.2 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain DUF5012 PF16404.5 EMC94214.1 - 0.014 15.5 0.3 0.054 13.6 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) NmrA PF05368.13 EMC94216.1 - 6.2e-16 58.7 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC94216.1 - 6.4e-16 58.8 0.0 1.4e-15 57.7 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC94216.1 - 7.3e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMC94216.1 - 0.00013 22.2 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EMC94216.1 - 0.00067 20.1 0.1 0.0012 19.3 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EMC94216.1 - 0.0013 18.8 0.1 0.0022 18.1 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EMC94216.1 - 0.0025 17.0 0.1 0.0076 15.4 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein ApbA PF02558.16 EMC94216.1 - 0.046 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EMC94216.1 - 0.054 14.1 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 EMC94216.1 - 0.064 12.3 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CoA_binding PF02629.19 EMC94216.1 - 0.067 13.9 0.2 0.16 12.6 0.2 1.6 1 0 0 1 1 1 0 CoA binding domain Ldh_1_N PF00056.23 EMC94216.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 EMC94216.1 - 0.2 11.1 0.7 0.62 9.5 0.4 1.7 1 1 1 2 2 2 0 short chain dehydrogenase NUDIX PF00293.28 EMC94217.1 - 1.1e-13 51.3 2.1 3e-12 46.7 0.2 2.5 1 1 2 3 3 3 2 NUDIX domain SNAP PF14938.6 EMC94220.1 - 0.053 12.9 0.1 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF3362 PF11842.8 EMC94220.1 - 0.066 13.5 0.0 0.091 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) OmdA PF13376.6 EMC94220.1 - 0.12 12.4 0.4 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated SQHop_cyclase_C PF13243.6 EMC94222.1 - 3.3e-46 157.9 0.2 6.1e-44 150.4 0.3 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EMC94222.1 - 3e-41 141.4 6.6 2.2e-33 115.6 0.2 3.9 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EMC94222.1 - 1.7e-23 82.0 15.4 1.3e-08 34.4 0.9 5.8 5 2 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EMC94222.1 - 0.00025 20.2 0.5 0.0055 15.8 0.1 3.1 2 1 0 2 2 2 1 A-macroglobulin TED domain ANTAR PF03861.14 EMC94222.1 - 0.21 11.4 0.1 0.43 10.5 0.1 1.5 1 0 0 1 1 1 0 ANTAR domain zf-RanBP PF00641.18 EMC94223.1 - 3.4e-19 67.9 11.0 6.8e-11 41.3 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EMC94223.1 - 3.7e-07 29.9 0.0 1e-05 25.2 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 EMC94223.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 Exonuclease Tudor_3 PF18115.1 EMC94224.1 - 1.6e-18 66.3 0.1 1.6e-18 66.3 0.1 1.9 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 EMC94224.1 - 1.8e-07 31.4 0.0 3.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 EMC94224.1 - 0.013 15.9 0.0 0.083 13.3 0.0 2.4 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ribonucleas_3_3 PF14622.6 EMC94225.1 - 1.7e-27 96.1 0.0 4.6e-27 94.7 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EMC94225.1 - 5.9e-07 30.1 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain HAT_KAT11 PF08214.11 EMC94226.1 - 2.3e-73 247.5 0.0 8.4e-73 245.7 0.0 1.8 2 0 0 2 2 2 1 Histone acetylation protein NmrA PF05368.13 EMC94227.1 - 1.1e-69 234.6 0.0 1.4e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC94227.1 - 2.8e-10 40.4 0.0 3.8e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAP PF00956.18 EMC94229.1 - 5.4e-29 101.2 0.8 1.6e-28 99.7 0.8 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Pep1_7 PF17232.2 EMC94229.1 - 0.0046 17.4 1.1 0.74 10.3 0.1 2.5 2 0 0 2 2 2 2 Elicitor peptide 1-7 PSI PF01437.25 EMC94230.1 - 6.7e-06 26.6 9.3 1.2e-05 25.7 9.3 1.5 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 EMC94230.1 - 0.044 13.5 12.4 0.075 12.8 12.4 1.6 1 1 0 1 1 1 0 Integrin plexin domain Col_cuticle_N PF01484.17 EMC94230.1 - 9.3 6.4 7.6 2.9 8.0 1.9 2.3 1 1 1 2 2 2 0 Nematode cuticle collagen N-terminal domain EMP24_GP25L PF01105.24 EMC94233.1 - 1.4e-47 162.0 0.0 1.6e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Glycogen_syn PF05693.13 EMC94234.1 - 0 1134.2 0.0 0 1134.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EMC94234.1 - 0.00016 21.3 0.0 0.042 13.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMC94234.1 - 0.0014 19.1 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 EMC94234.1 - 0.0016 18.9 0.0 0.82 10.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMC94234.1 - 0.0019 18.2 0.2 0.0036 17.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 EMC94234.1 - 0.026 14.2 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF759 PF05537.11 EMC94234.1 - 0.56 9.0 3.3 0.43 9.4 0.6 1.9 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) Herpes_LMP1 PF05297.11 EMC94237.1 - 1.5 8.0 6.3 1.7 7.8 6.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ndc1_Nup PF09531.10 EMC94237.1 - 4.4 5.9 8.0 4.7 5.8 8.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 EMC94237.1 - 5.3 6.9 6.0 6 6.8 6.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SPC22 PF04573.12 EMC94239.1 - 4.6e-39 133.6 0.6 1.2e-27 96.5 0.1 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Podoplanin PF05808.11 EMC94240.1 - 7.3 6.7 7.6 6 7.0 6.3 1.5 1 1 1 2 2 2 0 Podoplanin Spc29 PF17082.5 EMC94241.1 - 0.044 13.6 1.3 0.28 11.0 1.0 2.2 1 1 0 2 2 2 0 Spindle Pole Component 29 Methyltransf_23 PF13489.6 EMC94244.1 - 2.2e-12 47.1 0.0 4.1e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC94244.1 - 2e-07 31.6 0.0 2.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC94244.1 - 4.5e-07 30.5 0.0 6.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC94244.1 - 6.1e-05 22.9 0.0 7.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC94244.1 - 0.0012 18.3 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMC94244.1 - 0.0013 19.5 0.0 0.0018 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EMC94244.1 - 0.0023 18.9 0.0 0.0046 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EMC94244.1 - 0.078 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DEAD PF00270.29 EMC94246.1 - 7.1e-42 143.1 0.1 1.2e-41 142.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC94246.1 - 3e-32 111.3 0.0 1.3e-31 109.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EMC94246.1 - 0.00039 20.2 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMC94246.1 - 0.0015 18.8 0.0 0.012 16.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EMC94246.1 - 0.0022 18.0 0.0 0.004 17.2 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EMC94246.1 - 0.037 14.0 0.2 0.13 12.2 0.2 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 EMC94246.1 - 0.059 13.2 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Helicase TniB PF05621.11 EMC94246.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EMC94246.1 - 0.23 11.7 1.2 1.3 9.3 1.2 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 EMC94247.1 - 1.9e-75 252.7 0.3 8.6e-75 250.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EMC94247.1 - 1.4e-25 89.6 1.9 2e-25 89.1 0.7 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EMC94247.1 - 1.2e-14 53.9 1.4 2.3e-14 52.9 1.4 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EMC94247.1 - 3.5e-08 33.5 2.4 7.9e-07 29.2 0.4 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC94247.1 - 4.4e-07 30.1 1.6 3.3e-05 24.1 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP9_N PF16958.5 EMC94247.1 - 0.0008 19.5 13.1 0.0015 18.6 2.1 3.0 3 1 1 4 4 4 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 EMC94247.1 - 0.0028 17.9 0.2 0.14 12.5 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EMC94247.1 - 0.081 13.8 1.2 24 6.1 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMC94247.1 - 4.3 8.0 5.2 24 5.6 0.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Voldacs PF03517.13 EMC94249.1 - 5.6e-20 71.9 2.0 7.3e-10 39.1 0.8 2.3 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling Epimerase PF01370.21 EMC94250.1 - 1.3e-10 41.2 0.1 2.5e-09 37.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC94250.1 - 3.3e-07 30.4 0.0 4.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EMC94250.1 - 2e-05 23.7 0.1 0.00011 21.3 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EMC94250.1 - 4.7e-05 23.1 0.2 0.00032 20.3 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EMC94250.1 - 0.00024 20.6 0.1 0.036 13.5 0.0 2.4 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 EMC94250.1 - 0.0039 16.5 0.1 0.0064 15.8 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Polysacc_synt_2 PF02719.15 EMC94250.1 - 0.097 11.8 0.4 0.28 10.3 0.0 1.9 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 EMC94250.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Syntaxin-6_N PF09177.11 EMC94252.1 - 2.6e-22 79.2 1.8 7.7e-22 77.7 0.2 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EMC94252.1 - 0.00017 21.5 0.4 0.00017 21.5 0.4 2.6 3 0 0 3 3 2 1 SNARE domain Use1 PF09753.9 EMC94252.1 - 0.0011 18.7 0.6 0.0024 17.6 0.6 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 HMMR_N PF15905.5 EMC94252.1 - 0.0032 17.0 1.9 0.0085 15.6 0.3 1.9 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Prominin PF05478.11 EMC94252.1 - 0.0053 14.8 0.5 0.074 11.0 0.1 2.0 2 0 0 2 2 2 1 Prominin DUF1664 PF07889.12 EMC94252.1 - 0.042 13.9 6.6 1.4 9.0 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EMC94252.1 - 0.052 13.6 5.1 0.51 10.4 1.1 2.4 2 1 0 2 2 2 0 Laminin Domain II STAT_alpha PF01017.20 EMC94252.1 - 0.053 13.4 0.3 0.053 13.4 0.3 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF4795 PF16043.5 EMC94252.1 - 0.099 12.2 2.4 0.35 10.4 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4047 PF13256.6 EMC94252.1 - 0.1 12.8 0.3 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) YtxH PF12732.7 EMC94252.1 - 0.11 13.1 0.5 0.87 10.2 0.5 2.5 1 1 0 1 1 1 0 YtxH-like protein ArAE_2_N PF10337.9 EMC94252.1 - 0.11 11.5 0.3 0.3 10.1 0.1 1.6 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal Baculo_F PF12259.8 EMC94252.1 - 0.13 10.8 0.2 0.23 9.9 0.1 1.4 2 0 0 2 2 2 0 Baculovirus F protein Spc7 PF08317.11 EMC94252.1 - 0.26 10.1 4.5 0.47 9.3 0.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2205 PF10224.9 EMC94252.1 - 0.41 10.7 2.9 2.2 8.3 0.0 3.2 3 1 0 3 3 3 0 Short coiled-coil protein Baculo_PEP_C PF04513.12 EMC94252.1 - 0.44 10.6 4.1 7.3 6.6 1.8 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 EMC94252.1 - 0.61 10.2 3.8 1.6 8.8 1.3 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF2650 PF10853.8 EMC94252.1 - 1.1 9.0 3.0 1.7 8.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) WXG100 PF06013.12 EMC94252.1 - 2.6 8.4 8.3 25 5.2 0.7 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG GCIP PF13324.6 EMC94252.1 - 2.8 7.5 9.9 4 7.0 5.2 2.3 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting COG2 PF06148.11 EMC94252.1 - 3.9 7.6 8.6 5.9 7.0 3.5 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.16 EMC94252.1 - 4.6 7.8 6.1 31 5.1 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 Methyltransf_32 PF13679.6 EMC94253.1 - 3.9e-25 88.7 0.0 6.3e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain IBR PF01485.21 EMC94255.1 - 3.3e-07 30.4 6.7 3.3e-07 30.4 6.7 2.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain ACT_7 PF13840.6 EMC94256.1 - 8.6e-23 79.9 0.0 2.6e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 ACT domain IPP-2 PF04979.14 EMC94257.1 - 5.7e-21 75.6 12.8 5.7e-21 75.6 12.8 2.2 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) FAD_binding_4 PF01565.23 EMC94258.1 - 9e-15 54.6 4.9 4e-14 52.5 4.9 2.1 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMC94258.1 - 7.4e-07 29.2 0.1 1.6e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ofd1_CTDD PF10637.9 EMC94259.1 - 5.6e-84 281.5 0.6 1.1e-77 260.9 1.4 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EMC94259.1 - 1.3e-24 86.7 0.0 5.8e-24 84.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EMC94259.1 - 2.2e-12 47.7 0.2 7.3e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MARVEL PF01284.23 EMC94260.1 - 6.6e-05 23.0 6.1 6.6e-05 23.0 6.1 2.2 2 0 0 2 2 2 1 Membrane-associating domain ATP-synt_8 PF00895.20 EMC94260.1 - 0.11 13.0 4.3 2.7 8.5 0.2 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 DUF4690 PF15756.5 EMC94260.1 - 0.42 11.2 1.1 0.77 10.4 0.1 1.7 2 0 0 2 2 2 0 Small Novel Rich in Cartilage RabGAP-TBC PF00566.18 EMC94261.1 - 3.9e-48 163.9 0.0 5.4e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EMC94261.1 - 0.081 12.9 1.0 23 5.2 0.1 3.5 3 0 0 3 3 3 0 EF-hand domain DUF1688 PF07958.11 EMC94263.1 - 6.2e-185 614.9 0.0 7e-185 614.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Sdh_cyt PF01127.22 EMC94264.1 - 4.7e-23 81.5 5.5 6.8e-23 81.0 5.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Acetyltransf_10 PF13673.7 EMC94265.1 - 1.3e-12 47.7 0.0 4.3e-12 46.1 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC94265.1 - 1.6e-10 41.2 0.0 2.5e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC94265.1 - 5.5e-10 39.5 0.0 4.5e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC94265.1 - 7.3e-09 35.8 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMC94265.1 - 0.0033 17.5 0.0 0.0069 16.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EMC94265.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_15 PF17013.5 EMC94265.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase zf-CHY PF05495.12 EMC94266.1 - 1.3e-11 44.8 20.6 2.5e-11 43.9 20.6 1.4 1 0 0 1 1 1 1 CHY zinc finger zf-RRPl_C4 PF17026.5 EMC94266.1 - 0.0019 18.3 1.9 0.0019 18.3 1.9 1.9 1 1 1 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type Evr1_Alr PF04777.13 EMC94266.1 - 9 6.8 11.7 3e+02 1.9 11.7 2.5 1 1 0 1 1 1 0 Erv1 / Alr family Exo_endo_phos PF03372.23 EMC94267.1 - 4e-10 39.6 0.0 5e-09 36.0 0.0 2.5 2 2 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 EMC94267.1 - 0.54 11.2 3.3 13 6.9 0.3 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat GFA PF04828.14 EMC94268.1 - 7.8e-10 39.0 1.7 7.8e-10 39.0 1.7 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.12 EMC94268.1 - 0.44 10.5 5.4 7.3 6.5 0.3 2.6 2 0 0 2 2 2 0 LSD1 zinc finger HDA2-3 PF11496.8 EMC94269.1 - 7.1e-17 61.5 0.1 1.7e-14 53.7 0.1 2.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Latarcin PF10279.9 EMC94269.1 - 0.074 13.5 0.0 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 Latarcin precursor Fib_alpha PF08702.10 EMC94269.1 - 2.7 8.2 9.2 11 6.2 3.8 2.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3138 PF11336.8 EMC94269.1 - 6.5 5.2 7.3 1 7.9 2.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3138) TAF6_C PF07571.13 EMC94271.1 - 1.2e-29 102.4 0.0 2.9e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EMC94271.1 - 7e-25 87.0 0.2 1.7e-24 85.7 0.2 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EMC94271.1 - 4.1e-06 27.2 0.2 1.2e-05 25.7 0.2 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EMC94271.1 - 0.00031 21.0 0.1 0.001 19.3 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EMC94271.1 - 0.00063 19.8 0.4 0.0014 18.7 0.4 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EMC94271.1 - 0.0045 17.1 0.2 0.17 12.0 0.2 2.9 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EMC94271.1 - 0.0058 16.6 0.2 0.018 15.0 0.1 1.9 2 0 0 2 2 2 1 Bromodomain associated CENP-S PF15630.6 EMC94271.1 - 0.016 15.6 0.1 0.04 14.3 0.1 1.6 1 0 0 1 1 1 0 CENP-S protein CitG PF01874.16 EMC94271.1 - 0.056 13.1 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase POT1 PF02765.17 EMC94274.1 - 5.2e-09 36.1 0.0 1.8e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 PALP PF00291.25 EMC94275.1 - 3e-68 230.4 0.1 4e-68 230.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.7 EMC94276.1 - 8e-82 274.7 0.5 2.2e-81 273.3 0.1 2.0 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EMC94276.1 - 2e-07 30.7 4.8 0.096 13.0 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EMC94276.1 - 9.8e-07 29.1 14.0 0.00024 21.4 3.2 5.4 4 2 1 5 5 5 2 HEAT repeats Cnd1 PF12717.7 EMC94276.1 - 3.9e-05 23.7 0.9 1.4 8.9 0.1 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EMC94276.1 - 0.019 15.5 11.3 4.6 7.9 0.2 6.7 5 1 2 7 7 7 0 HEAT-like repeat CLASP_N PF12348.8 EMC94276.1 - 0.057 13.0 0.9 1 8.9 0.0 2.6 3 0 0 3 3 3 0 CLASP N terminal Scramblase PF03803.15 EMC94280.1 - 1.7e-52 177.9 0.0 1.4e-26 93.2 0.0 3.0 3 0 0 3 3 3 3 Scramblase Roughex PF06020.11 EMC94280.1 - 2.3 7.2 5.6 4.1 6.4 5.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Forkhead_N PF08430.12 EMC94280.1 - 5 7.7 8.3 8.7 7.0 6.3 2.3 2 0 0 2 2 2 0 Forkhead N-terminal region tRNA_int_endo PF01974.17 EMC94281.1 - 6e-20 71.1 0.1 1.1e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EMC94281.1 - 2.2e-05 24.1 0.0 0.0017 18.0 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain NAM-associated PF14303.6 EMC94281.1 - 0.018 15.7 0.0 0.15 12.7 0.0 2.4 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain UBA PF00627.31 EMC94282.1 - 1.2e-05 25.0 0.1 3.3e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_1 PF00515.28 EMC94282.1 - 3.4e-05 23.5 0.3 1.3 8.9 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC94282.1 - 4.8e-05 23.1 4.5 1.3 9.3 0.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMC94282.1 - 0.024 14.9 0.5 0.65 10.3 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 EMC94282.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain Glyco_hydro_cc PF11790.8 EMC94285.1 - 2.2e-31 109.3 0.8 2.8e-31 108.9 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Thaumatin PF00314.17 EMC94286.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Thaumatin family SLT PF01464.20 EMC94288.1 - 1.6e-05 24.5 0.3 0.00022 20.9 0.3 2.1 1 1 0 1 1 1 1 Transglycosylase SLT domain Big_2 PF02368.18 EMC94288.1 - 0.37 10.7 2.3 0.93 9.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) WD40 PF00400.32 EMC94289.1 - 3.7e-35 119.4 25.1 3.4e-08 34.0 0.1 11.7 12 1 1 13 13 13 5 WD domain, G-beta repeat Utp12 PF04003.12 EMC94289.1 - 4.2e-23 81.7 0.3 6.6e-23 81.1 0.3 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EMC94289.1 - 1.5e-16 60.4 0.0 0.26 11.6 0.0 9.4 5 1 4 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMC94289.1 - 1.3e-06 28.5 0.1 0.084 12.7 0.0 5.5 4 1 2 6 6 6 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EMC94289.1 - 1.5e-05 24.1 0.3 3.4 6.5 0.1 5.7 4 2 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EMC94289.1 - 0.001 17.8 1.7 8.9 4.8 0.0 4.6 3 1 1 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EMC94289.1 - 0.083 12.2 0.0 7.7 5.7 0.0 3.1 2 1 1 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 EMC94289.1 - 0.12 10.8 0.1 1.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 EMC94289.1 - 0.66 10.5 10.5 1.5 9.4 0.1 5.4 5 1 0 5 5 5 0 PQQ-like domain Septin PF00735.18 EMC94290.1 - 1.4e-112 375.5 0.2 2e-112 375.1 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EMC94290.1 - 1.4e-07 31.6 0.0 3.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMC94290.1 - 7.2e-06 26.0 0.0 4.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EMC94290.1 - 3.7e-05 23.4 2.0 0.00021 20.9 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EMC94290.1 - 0.00082 19.7 0.3 0.003 17.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EMC94290.1 - 0.003 17.1 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AIG1 PF04548.16 EMC94290.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 EMC94290.1 - 0.0066 16.7 0.1 0.015 15.5 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 EMC94290.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EMC94290.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain FOXP-CC PF16159.5 EMC94290.1 - 0.011 16.3 1.8 0.023 15.3 0.9 2.0 1 1 0 1 1 1 0 FOXP coiled-coil domain AAA_16 PF13191.6 EMC94290.1 - 0.027 14.9 0.7 0.075 13.4 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 EMC94290.1 - 0.035 13.2 0.4 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 EMC94290.1 - 0.048 14.2 0.1 0.3 11.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 EMC94290.1 - 0.053 12.8 0.0 0.058 12.6 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 EMC94290.1 - 0.055 13.1 0.4 0.16 11.5 0.4 1.8 1 1 0 1 1 1 0 Ras family NACHT PF05729.12 EMC94290.1 - 0.075 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EMC94290.1 - 0.099 12.2 0.3 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EMC94290.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EMC94290.1 - 0.11 12.2 0.3 4.5 7.0 0.3 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EMC94290.1 - 0.24 11.1 0.6 13 5.5 0.1 2.6 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EMC94290.1 - 0.7 9.9 6.1 4.8 7.2 0.0 3.0 2 1 1 3 3 3 0 Dynamin family WD40 PF00400.32 EMC94291.1 - 1.5e-30 104.8 8.2 4.3e-07 30.5 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC94291.1 - 4.2e-10 39.8 0.3 0.24 11.7 0.0 5.6 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EMC94291.1 - 0.0014 18.6 0.0 2.1 8.4 0.0 3.1 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region DUF5046 PF16465.5 EMC94291.1 - 0.0082 15.6 1.3 1.4 8.3 0.2 2.9 1 1 0 2 2 2 1 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 EMC94291.1 - 0.01 16.3 11.8 0.085 13.4 0.6 4.7 4 1 0 4 4 4 0 PQQ-like domain WD40_like PF17005.5 EMC94291.1 - 0.011 15.1 0.0 0.11 11.8 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain PQQ PF01011.21 EMC94291.1 - 0.013 15.4 0.0 0.52 10.3 0.1 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat SUKH-4 PF14435.6 EMC94291.1 - 0.039 14.0 0.5 0.23 11.5 0.0 2.4 1 1 0 2 2 2 0 SUKH-4 immunity protein Emaravirus_P4 PF16505.5 EMC94291.1 - 0.088 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Aa_trans PF01490.18 EMC94292.1 - 2.8e-21 75.7 37.8 3.5e-21 75.4 37.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 EMC94293.1 - 3.1e-34 118.5 29.0 4.2e-34 118.0 29.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_7 PF00840.20 EMC94293.1 - 0.15 10.8 0.0 0.35 9.5 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 7 F-box-like PF12937.7 EMC94294.1 - 1.8e-09 37.3 0.1 5.7e-09 35.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC94294.1 - 0.002 18.0 5.9 0.005 16.7 0.5 3.8 4 1 0 4 4 4 1 F-box domain Methyltransf_11 PF08241.12 EMC94295.1 - 3e-12 47.0 0.0 4.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC94295.1 - 6.5e-11 42.8 0.0 1.7e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC94295.1 - 1.5e-05 24.8 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC94295.1 - 0.0017 19.1 0.0 0.003 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 EMC94296.1 - 2.4e-32 112.2 32.8 2.4e-32 112.2 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_desaturase PF00487.24 EMC94299.1 - 5.9e-13 49.2 34.8 9.9e-13 48.5 34.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase CPSase_L_D2 PF02786.17 EMC94303.1 - 6.7e-74 247.9 0.0 9.9e-74 247.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EMC94303.1 - 8.6e-38 128.8 0.0 5.3e-37 126.2 0.0 2.2 1 1 1 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EMC94303.1 - 1.2e-35 122.3 0.0 2.5e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EMC94303.1 - 2.4e-10 40.1 1.5 6.2e-10 38.8 1.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EMC94303.1 - 1.9e-09 37.4 0.0 4.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EMC94303.1 - 2.5e-08 33.7 0.0 5.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EMC94303.1 - 0.0003 20.9 0.0 0.00055 20.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EMC94303.1 - 0.0031 17.3 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Biotin-lipoyl like RimK PF08443.11 EMC94303.1 - 0.024 14.2 0.0 0.074 12.6 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 EMC94303.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 EMC94303.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Peptidase_M24 PF00557.24 EMC94305.1 - 1.6e-48 165.2 0.1 1.9e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EMC94305.1 - 1.1e-19 70.5 8.3 2.2e-19 69.5 8.3 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EMC94305.1 - 0.0067 16.5 6.9 0.0067 16.5 6.9 2.4 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.14 EMC94306.1 - 1.2e-50 171.0 11.7 1.3e-50 170.8 11.7 1.0 1 0 0 1 1 1 1 Cornichon protein NMT_C PF02799.15 EMC94307.1 - 5.6e-76 254.7 0.0 7.7e-76 254.3 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EMC94307.1 - 1.1e-68 230.1 0.0 5.3e-68 227.9 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EMC94307.1 - 7.9e-05 22.7 0.0 0.00066 19.7 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC94307.1 - 0.0008 19.6 0.2 0.0053 17.0 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family YL1 PF05764.13 EMC94307.1 - 0.012 15.7 9.1 0.028 14.5 9.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.11 EMC94307.1 - 0.039 13.3 8.9 0.064 12.7 8.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Med8 PF10232.9 EMC94307.1 - 0.097 12.3 1.8 0.17 11.4 1.8 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Nop14 PF04147.12 EMC94307.1 - 0.27 9.4 8.8 0.41 8.8 8.8 1.2 1 0 0 1 1 1 0 Nop14-like family IHABP4_N PF16174.5 EMC94307.1 - 0.36 11.4 9.9 0.66 10.6 9.9 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RNA_polI_A34 PF08208.11 EMC94307.1 - 0.66 10.0 9.7 1.2 9.2 9.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3381 PF11861.8 EMC94307.1 - 1.3 8.8 8.1 2.8 7.7 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2052 PF09747.9 EMC94307.1 - 1.6 8.8 8.5 4.1 7.5 8.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 EMC94307.1 - 1.8 6.7 6.9 2.9 6.1 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EMC94307.1 - 4.6 7.0 6.7 7.9 6.2 6.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AMP-binding PF00501.28 EMC94308.1 - 2.8e-101 339.2 0.0 3.4e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC94308.1 - 8.5e-13 49.1 0.1 1.8e-12 48.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Form_Nir_trans PF01226.17 EMC94309.1 - 2.9e-45 154.5 11.3 3.4e-45 154.2 11.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Tmemb_55A PF09788.9 EMC94309.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A PBP_N PF17093.5 EMC94309.1 - 0.2 11.9 0.5 0.35 11.1 0.5 1.3 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Ras PF00071.22 EMC94310.1 - 1.6e-59 200.2 0.2 1.8e-59 200.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC94310.1 - 1.4e-36 125.3 0.2 4.9e-36 123.6 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC94310.1 - 2.2e-15 56.6 0.0 2.7e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMC94310.1 - 2e-06 27.9 0.0 3.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMC94310.1 - 2.4e-06 27.2 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMC94310.1 - 5.5e-06 25.9 0.0 6.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EMC94310.1 - 2.4e-05 24.3 1.2 0.14 12.0 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EMC94310.1 - 0.0082 16.5 0.3 0.017 15.5 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMC94310.1 - 0.08 13.2 0.1 2.9 8.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 EMC94310.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Syja_N PF02383.18 EMC94311.1 - 2.8e-91 306.1 0.3 3.7e-91 305.8 0.3 1.1 1 0 0 1 1 1 1 SacI homology domain Metallophos PF00149.28 EMC94312.1 - 4.5e-15 56.7 1.0 5.9e-15 56.3 0.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMC94312.1 - 0.00024 21.3 0.1 0.0033 17.6 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FAD_binding_3 PF01494.19 EMC94313.1 - 4.9e-42 144.4 0.0 6.4e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC94313.1 - 1.2e-05 25.1 0.0 0.013 15.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC94313.1 - 0.00016 21.1 0.1 0.00082 18.7 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC94313.1 - 0.00029 21.0 0.0 0.002 18.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMC94313.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EMC94313.1 - 0.0032 16.6 0.1 0.0051 15.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EMC94313.1 - 0.0048 17.4 0.1 0.35 11.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC94313.1 - 0.0053 16.0 0.1 0.009 15.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 EMC94313.1 - 0.051 12.1 0.1 5.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) K_oxygenase PF13434.6 EMC94313.1 - 0.13 11.3 0.1 3 6.9 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EMC94313.1 - 0.18 10.5 0.0 0.39 9.4 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein SMC_N PF02463.19 EMC94314.1 - 6.6e-26 91.1 0.2 1e-25 90.5 0.2 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMC94314.1 - 3.5e-17 63.6 15.6 3.5e-17 63.6 15.6 4.8 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 EMC94314.1 - 9.4e-06 25.6 12.6 1.5e-05 24.9 2.3 3.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EMC94314.1 - 5.1e-05 23.2 0.1 0.0095 15.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMC94314.1 - 9.8e-05 22.0 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EMC94314.1 - 0.054 13.1 0.0 0.054 13.1 0.0 5.1 5 2 1 6 6 6 0 AAA domain RNA_helicase PF00910.22 EMC94314.1 - 0.063 13.7 1.5 0.64 10.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA PF00004.29 EMC94314.1 - 1.7 9.1 4.0 1.2 9.6 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) POP1 PF06978.11 EMC94315.1 - 4.8e-74 248.8 15.4 1.2e-73 247.5 15.4 1.7 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EMC94315.1 - 2.1e-33 114.5 1.7 7.1e-33 112.8 1.7 2.0 1 0 0 1 1 1 1 POPLD (NUC188) domain ARPC4 PF05856.12 EMC94316.1 - 1.3e-78 262.3 1.7 1.5e-78 262.2 1.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Pro-kuma_activ PF09286.11 EMC94319.1 - 9.4e-36 123.2 0.0 1.7e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMC94319.1 - 0.0055 16.0 0.1 0.0086 15.4 0.1 1.2 1 0 0 1 1 1 1 Subtilase family ABC2_membrane PF01061.24 EMC94320.1 - 2.3e-38 131.8 21.3 4.3e-38 130.8 21.3 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EMC94320.1 - 3.4e-26 92.4 0.1 1.5e-25 90.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EMC94320.1 - 2.5e-05 23.6 22.5 2.5e-05 23.6 22.5 2.2 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 EMC94320.1 - 0.00027 20.8 0.0 0.74 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EMC94320.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EMC94320.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EMC94320.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EMC94320.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Biotin_lipoyl PF00364.22 EMC94321.1 - 1.9e-20 72.5 1.8 4.2e-20 71.3 1.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EMC94321.1 - 8.1e-09 35.7 0.0 2.4e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EMC94321.1 - 7.5e-05 22.5 1.1 0.00079 19.2 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 EMC94321.1 - 0.056 14.2 1.3 0.41 11.4 0.5 2.5 2 1 0 2 2 2 0 HlyD family secretion protein YqfD PF06898.11 EMC94321.1 - 0.36 9.6 0.6 0.62 8.8 0.6 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD TMEM223 PF14640.6 EMC94322.1 - 0.0027 17.9 0.4 0.0066 16.6 0.2 1.7 2 0 0 2 2 2 1 Transmembrane protein 223 DUF2189 PF09955.9 EMC94322.1 - 0.0041 17.3 1.0 0.0072 16.6 1.0 1.3 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2189) AAA PF00004.29 EMC94323.1 - 1.2e-16 61.3 0.0 1.8e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) adh_short_C2 PF13561.6 EMC94324.1 - 2.8e-52 177.6 3.3 3.2e-52 177.4 3.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC94324.1 - 1.5e-49 168.1 1.9 3.5e-49 166.9 1.4 1.7 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMC94324.1 - 8.4e-11 42.1 0.2 1.9e-10 40.9 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMC94324.1 - 3.2e-05 23.5 0.1 8e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EMC94324.1 - 7.8e-05 22.9 0.0 0.00024 21.4 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 EMC94324.1 - 0.00027 21.5 0.0 0.033 14.8 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EMC94324.1 - 0.0012 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EMC94324.1 - 0.0021 17.2 0.6 0.0044 16.2 0.1 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Methyltransf_12 PF08242.12 EMC94324.1 - 0.006 17.3 0.0 0.012 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EMC94324.1 - 0.0073 15.7 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMC94324.1 - 0.0076 15.3 0.1 0.0096 15.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ATP_bind_2 PF03668.15 EMC94324.1 - 0.0082 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop ATPase protein family Polysacc_synt_2 PF02719.15 EMC94324.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 EMC94324.1 - 0.012 16.2 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.13 EMC94324.1 - 0.031 13.8 0.0 0.077 12.5 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Gpr1_Fun34_YaaH PF01184.19 EMC94325.1 - 5.8e-90 300.4 20.5 6.8e-90 300.2 20.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family WSC PF01822.19 EMC94328.1 - 5.9e-31 106.5 29.2 5e-16 58.7 8.0 2.3 2 0 0 2 2 2 2 WSC domain PAN_3 PF08277.12 EMC94328.1 - 0.59 10.0 5.8 0.58 10.0 0.5 2.5 2 0 0 2 2 2 0 PAN-like domain Toxin_35 PF10530.9 EMC94328.1 - 0.62 10.1 5.6 12 5.9 0.3 2.6 2 0 0 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold AhpC-TSA PF00578.21 EMC94329.1 - 1.2e-28 99.5 0.0 1.7e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMC94329.1 - 6.3e-12 45.4 0.0 9.1e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EMC94329.1 - 0.00011 22.0 0.2 0.00022 21.0 0.0 1.6 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin MARVEL PF01284.23 EMC94330.1 - 0.0029 17.6 19.4 0.0038 17.2 19.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain LrgB PF04172.16 EMC94330.1 - 0.0055 16.3 4.1 0.0055 16.3 4.1 1.4 2 0 0 2 2 2 1 LrgB-like family DUF5337 PF17272.2 EMC94330.1 - 0.016 15.0 2.8 0.016 15.0 2.8 4.0 2 1 2 4 4 4 0 Family of unknown function (DUF5337) Cu-oxidase_3 PF07732.15 EMC94331.1 - 1.8e-42 144.1 3.2 1.8e-42 144.1 3.2 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMC94331.1 - 9.3e-35 119.3 5.3 7.2e-31 106.8 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EMC94331.1 - 1.8e-30 106.2 0.0 7e-30 104.3 0.0 2.0 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.14 EMC94333.1 - 7.5e-36 124.0 2.9 2.9e-35 122.1 2.8 1.7 1 1 0 1 1 1 1 Phosphoesterase family FCP1_C PF09309.10 EMC94333.1 - 0.23 11.3 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 FCP1, C-terminal VIT1 PF01988.19 EMC94334.1 - 1.7e-57 194.7 9.7 2.1e-57 194.4 9.7 1.1 1 0 0 1 1 1 1 VIT family Mannosyl_trans PF05007.13 EMC94335.1 - 1.3e-77 261.2 13.1 1.6e-77 260.9 13.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EMC94335.1 - 8.3e-14 51.4 5.0 1.6e-13 50.5 5.0 1.6 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EMC94335.1 - 2.8e-05 23.9 20.0 2.8e-05 23.9 20.0 2.5 1 1 1 2 2 2 1 Glycosyltransferase family 87 UbiA PF01040.18 EMC94337.1 - 2.6e-59 200.6 17.9 2.6e-59 200.6 17.9 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family Aminotran_1_2 PF00155.21 EMC94340.1 - 1.9e-43 149.1 0.0 2.3e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMC94340.1 - 2.2e-06 26.5 0.0 3.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EMC94340.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EMC94340.1 - 0.00016 20.8 0.0 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 EMC94340.1 - 0.022 13.7 0.0 0.38 9.6 0.0 2.2 1 1 0 1 1 1 0 Allinase OsmC PF02566.19 EMC94341.1 - 2.9e-14 53.3 0.0 4.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Fungal_trans PF04082.18 EMC94342.1 - 3.2e-06 26.4 1.5 6.1e-06 25.5 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC94343.1 - 0.043 13.9 12.2 0.14 12.3 12.2 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 EMC94344.1 - 3.2e-06 27.4 2.0 5.5e-05 23.4 1.8 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily WD40 PF00400.32 EMC94346.1 - 6.4e-21 74.3 10.8 1.2e-05 25.9 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC94346.1 - 2.6e-05 24.4 0.0 0.013 15.8 0.0 4.0 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_phi PF04931.13 EMC94346.1 - 6.3 4.8 21.6 14 3.6 21.3 1.6 2 0 0 2 2 2 0 DNA polymerase phi DPM2 PF07297.12 EMC94347.1 - 3.2e-33 113.9 0.8 3.6e-33 113.7 0.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EMC94347.1 - 0.00065 19.6 1.1 0.00076 19.4 1.1 1.1 1 0 0 1 1 1 1 PIG-P Cytochrom_C_asm PF01578.20 EMC94347.1 - 0.0089 15.8 0.1 0.0089 15.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C assembly protein LapA_dom PF06305.11 EMC94347.1 - 0.026 14.3 0.5 0.026 14.3 0.5 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain COX14 PF14880.6 EMC94347.1 - 0.035 13.9 2.6 0.06 13.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4229 PF14012.6 EMC94347.1 - 0.039 14.0 4.8 0.11 12.6 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) Phage_holin_3_6 PF07332.11 EMC94347.1 - 0.043 13.8 0.4 0.051 13.6 0.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DiS_P_DiS PF06750.13 EMC94347.1 - 0.085 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Arf PF00025.21 EMC94348.1 - 4.6e-54 182.5 0.0 5.4e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EMC94348.1 - 4e-11 42.7 0.0 2.3e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EMC94348.1 - 3.3e-07 30.6 0.0 1.1e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMC94348.1 - 4.9e-07 29.3 0.0 6.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EMC94348.1 - 7.1e-07 29.3 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EMC94348.1 - 7.9e-06 25.6 0.0 1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EMC94348.1 - 0.00078 18.9 0.0 0.00092 18.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 EMC94348.1 - 0.19 11.3 0.0 11 5.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2457 PF10446.9 EMC94349.1 - 1.6e-118 396.9 28.1 1.6e-118 396.9 28.1 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2457) XPG_N PF00752.17 EMC94351.1 - 4.8e-35 120.1 0.0 1.3e-34 118.7 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EMC94351.1 - 4.9e-26 90.9 0.0 1.4e-25 89.5 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 EMC94351.1 - 0.0048 16.7 5.3 0.0048 16.7 5.3 4.1 3 0 0 3 3 3 1 Ubiquitin interaction motif IMS PF00817.20 EMC94353.1 - 5.1e-41 140.2 0.2 1.1e-40 139.0 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EMC94353.1 - 2.7e-14 53.9 0.0 6.8e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EMC94353.1 - 0.0031 17.7 0.0 0.0076 16.5 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif CAF20 PF17052.5 EMC94353.1 - 0.011 15.9 0.2 0.033 14.4 0.2 1.8 1 0 0 1 1 1 0 Cap associated factor Vps36-NZF-N PF16988.5 EMC94353.1 - 0.11 11.9 0.5 0.77 9.2 0.1 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain GGGtGRT PF14057.6 EMC94353.1 - 0.14 11.1 0.3 0.21 10.5 0.3 1.2 1 0 0 1 1 1 0 GGGtGRT protein FMN_dh PF01070.18 EMC94354.1 - 4.7e-125 417.2 0.0 5.6e-125 417.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMC94354.1 - 3.4e-07 29.6 0.1 6.3e-07 28.7 0.1 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMC94354.1 - 2.6e-06 26.8 0.4 8.1e-06 25.2 0.0 1.9 2 1 1 3 3 3 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EMC94354.1 - 8.2e-05 22.2 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 EMC94354.1 - 0.0011 18.4 0.9 0.0018 17.8 0.9 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 EMC94354.1 - 0.047 12.9 0.0 0.096 11.9 0.0 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.14 EMC94354.1 - 0.056 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.16 EMC94356.1 - 1e-21 77.3 31.7 9.4e-14 51.1 1.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 EMC94356.1 - 5.1e-10 38.5 12.5 5.7e-07 28.4 4.1 3.4 3 0 0 3 3 3 3 MFS/sugar transport protein ATG22 PF11700.8 EMC94356.1 - 1.5e-06 27.2 2.0 0.00041 19.1 0.0 2.9 2 2 1 3 3 3 2 Vacuole effluxer Atg22 like DUF1772 PF08592.11 EMC94356.1 - 0.26 11.6 0.0 0.26 11.6 0.0 4.3 3 2 1 5 5 5 0 Domain of unknown function (DUF1772) Big_1 PF02369.16 EMC94356.1 - 0.38 10.8 3.9 16 5.6 2.3 2.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Hydrolase_6 PF13344.6 EMC94358.1 - 1.5e-30 105.3 0.0 3e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC94358.1 - 6.2e-14 51.8 0.0 1.4e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EMC94358.1 - 3.2e-11 43.9 0.0 1.8e-09 38.2 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMC94358.1 - 8e-05 22.8 0.1 0.15 12.1 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PDEase_I PF00233.19 EMC94359.1 - 4.7e-29 101.8 0.0 6.3e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MAJIN PF15077.6 EMC94359.1 - 8.8 6.0 8.4 4.3 7.1 1.9 2.4 2 0 0 2 2 2 0 Membrane-anchored junction protein Hexokinase_2 PF03727.16 EMC94362.1 - 1.2e-78 263.9 0.0 1.6e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EMC94362.1 - 7.7e-76 254.4 0.3 1.3e-75 253.7 0.3 1.3 1 0 0 1 1 1 1 Hexokinase AMP-binding PF00501.28 EMC94363.1 - 2.1e-60 204.5 0.0 2.8e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC94363.1 - 9.5e-05 23.3 0.0 0.00021 22.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4576 PF15144.6 EMC94363.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Glyco_hydro_31 PF01055.26 EMC94364.1 - 6e-88 296.0 13.1 1e-87 295.2 13.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EMC94364.1 - 0.00046 20.4 0.2 0.0026 18.0 0.2 2.4 1 1 0 1 1 1 1 Galactose mutarotase-like DUF1769 PF08588.10 EMC94366.1 - 2.2e-26 91.8 0.2 4.3e-26 90.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.20 EMC94367.1 - 4.6e-97 325.3 0.0 7.6e-97 324.6 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CHASE3 PF05227.13 EMC94367.1 - 0.0086 16.0 0.3 0.014 15.3 0.3 1.3 1 0 0 1 1 1 1 CHASE3 domain TetR_C_31 PF17940.1 EMC94367.1 - 0.046 13.9 0.1 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ipi1_N PF12333.8 EMC94369.1 - 2.2e-19 69.9 0.3 2.2e-19 69.9 0.3 2.2 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.17 EMC94370.1 - 3.7e-07 29.8 0.0 6.8e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 Roadblock/LC7 domain DUF348 PF03990.14 EMC94370.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain DUF1348 PF07080.11 EMC94371.1 - 2.5e-59 198.9 9.6 2.9e-59 198.7 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EMC94371.1 - 1.8e-06 28.5 0.0 2.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EMC94371.1 - 7.2e-06 26.4 0.0 9.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 EMC94371.1 - 0.0036 17.1 0.1 0.0052 16.6 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase NTF2 PF02136.20 EMC94371.1 - 0.019 15.5 0.1 5.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain KGK PF08872.10 EMC94371.1 - 0.2 12.2 5.2 1.2 9.7 3.0 2.2 1 1 1 2 2 2 0 KGK domain Fungal_trans PF04082.18 EMC94372.1 - 9.2e-16 57.7 0.1 1.5e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC94372.1 - 9.8e-08 32.0 9.6 1.9e-07 31.1 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_lectin PF07938.12 EMC94373.1 - 1.1e-10 41.5 0.1 1.3e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Fungal fucose-specific lectin DUF745 PF05335.13 EMC94374.1 - 0.055 13.2 2.0 0.13 12.0 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 EMC94374.1 - 0.13 12.3 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ANAPC_CDC26 PF10471.9 EMC94374.1 - 0.23 12.3 0.1 0.23 12.3 0.1 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Abhydrolase_6 PF12697.7 EMC94375.1 - 3.1e-19 70.5 0.1 4e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC94375.1 - 4.7e-12 46.1 0.2 1.5e-11 44.5 0.1 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC94375.1 - 9.3e-08 31.6 0.1 1.6e-07 30.9 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMC94375.1 - 0.00064 19.9 0.0 0.00073 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF900 PF05990.12 EMC94375.1 - 0.0077 15.8 0.0 0.022 14.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.7 EMC94375.1 - 0.0089 15.0 0.1 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme LCAT PF02450.15 EMC94375.1 - 0.0097 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase zf-XS PF03470.14 EMC94375.1 - 0.028 14.7 0.1 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 XS zinc finger domain Ndr PF03096.14 EMC94375.1 - 0.077 11.7 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Ndr family Ser_hydrolase PF06821.13 EMC94375.1 - 0.17 11.7 0.2 0.97 9.3 0.3 2.2 2 1 0 2 2 2 0 Serine hydrolase UPF0183 PF03676.14 EMC94376.1 - 1.4e-47 162.9 0.0 1.5e-31 110.1 0.0 3.2 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 EMC94377.1 - 6.6e-108 360.6 0.0 6.6e-108 360.6 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EMC94377.1 - 1.7e-23 83.3 0.0 1.5e-22 80.1 0.0 2.7 3 0 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 EMC94377.1 - 2.2e-07 31.3 2.0 2.2e-07 31.3 2.0 4.7 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding ApoLp-III PF07464.11 EMC94377.1 - 0.0061 16.7 2.5 0.0061 16.7 2.5 4.8 2 2 3 5 5 5 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 EMC94377.1 - 0.012 15.6 19.1 0.2 11.7 0.0 5.8 2 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG_C PF09333.11 EMC94377.1 - 0.37 11.2 6.5 3.7 8.0 0.2 4.2 3 1 0 3 3 3 0 Autophagy-related protein C terminal domain ACP_PD PF04336.12 EMC94377.1 - 0.53 10.7 3.4 29 5.2 0.1 4.0 2 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase Sirohm_synth_C PF14823.6 EMC94377.1 - 0.62 9.7 6.1 0.8 9.4 1.0 3.3 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal PAS_9 PF13426.7 EMC94378.1 - 1.2e-13 51.1 0.0 9.6e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EMC94378.1 - 0.0044 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PQ-loop PF04193.14 EMC94379.1 - 2.7e-34 116.7 2.2 3.8e-16 58.6 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat Glycos_transf_2 PF00535.26 EMC94380.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EMC94380.1 - 2 8.3 7.9 0.044 13.7 1.1 1.7 2 0 0 2 2 2 0 Glycosyl transferase family group 2 PrgI PF12666.7 EMC94380.1 - 8.3 7.2 9.7 0.55 11.0 3.0 2.3 2 0 0 2 2 2 0 PrgI family protein Epimerase PF01370.21 EMC94382.1 - 1.4e-34 119.7 0.0 6.4e-34 117.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC94382.1 - 3.5e-33 115.4 0.0 2.9e-32 112.4 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMC94382.1 - 1.8e-06 27.3 0.0 4.6e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EMC94382.1 - 6.8e-06 25.3 0.2 0.00012 21.3 0.2 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMC94382.1 - 0.00012 21.4 0.0 0.00089 18.5 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EMC94382.1 - 0.0079 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC94382.1 - 0.011 15.6 0.1 0.14 12.1 0.1 2.1 1 1 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 EMC94382.1 - 0.042 14.1 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EMC94382.1 - 0.14 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain zf-HC5HC2H_2 PF13832.6 EMC94383.1 - 4.4e-32 110.5 6.8 4.4e-32 110.5 6.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 EMC94383.1 - 8.9e-29 100.9 1.6 9.4e-29 100.8 0.0 1.9 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 EMC94383.1 - 1.1e-26 92.9 4.5 1.1e-26 92.9 4.5 2.6 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EMC94383.1 - 1.1e-13 50.5 1.3 1.1e-13 50.5 1.3 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EMC94383.1 - 2.9e-09 36.7 23.3 3e-09 36.6 9.6 2.5 2 0 0 2 2 2 2 PHD-finger TINF2_N PF14973.6 EMC94383.1 - 0.049 14.0 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus GCD14_N PF14801.6 EMC94386.1 - 6.8e-08 32.2 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term GCD14 PF08704.10 EMC94386.1 - 1.8e-05 24.6 0.0 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 EMC94386.1 - 0.15 12.7 0.0 20 6.0 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Myb_DNA-binding PF00249.31 EMC94388.1 - 2.7e-06 27.5 1.2 0.00014 22.0 0.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC94388.1 - 2.2e-05 24.6 0.9 0.00019 21.6 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Cation_efflux PF01545.21 EMC94389.1 - 3.8e-48 163.9 6.0 4.7e-48 163.6 6.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMC94389.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Beta-lactamase PF00144.24 EMC94390.1 - 8.3e-45 153.4 2.6 6.6e-44 150.5 2.6 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EMC94390.1 - 0.0088 15.5 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 EMC94390.1 - 0.01 15.4 0.1 0.038 13.6 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase enzyme family His_Phos_2 PF00328.22 EMC94391.1 - 2.2e-58 198.5 0.0 2.6e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FAD_binding_3 PF01494.19 EMC94392.1 - 4.6e-20 72.2 0.1 2.4e-19 69.8 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EMC94392.1 - 2.4e-05 23.5 0.0 0.0001 21.4 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 EMC94392.1 - 0.00062 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC94392.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC94392.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Beta-lactamase PF00144.24 EMC94393.1 - 1.5e-47 162.5 0.5 1.9e-47 162.1 0.5 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EMC94393.1 - 2.4e-08 34.4 0.0 5.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) PQ-loop PF04193.14 EMC94394.1 - 1.3e-23 82.5 7.1 1.5e-13 50.3 3.1 2.6 2 0 0 2 2 2 2 PQ loop repeat FAA_hydrolase_N PF09298.11 EMC94395.1 - 1.9e-26 92.3 0.0 2.8e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAA_hydrolase PF01557.18 EMC94395.1 - 2e-06 27.6 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Mur_ligase_M PF08245.12 EMC94396.1 - 1.5e-07 31.6 0.2 8.7e-07 29.1 0.2 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EMC94396.1 - 0.0071 16.6 0.1 0.018 15.3 0.1 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Qua1 PF16274.5 EMC94396.1 - 0.12 12.3 0.2 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Qua1 domain Herpes_BLLF1 PF05109.13 EMC94397.1 - 4.7 5.1 8.4 0.098 10.6 1.4 1.6 2 0 0 2 2 2 0 Herpes virus major outer envelope glycoprotein (BLLF1) Cmc1 PF08583.10 EMC94398.1 - 0.036 14.1 1.7 0.088 12.8 1.7 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Aldedh PF00171.22 EMC94401.1 - 1.6e-167 557.7 0.6 1.8e-167 557.5 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Flu_NS1 PF00600.19 EMC94401.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) Mpv17_PMP22 PF04117.12 EMC94402.1 - 3.9e-24 84.6 3.4 7.5e-24 83.7 3.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family NAPRTase PF04095.16 EMC94403.1 - 1.3e-58 198.5 0.2 1.6e-55 188.3 0.3 3.0 2 1 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EMC94403.1 - 4.3e-36 124.1 0.1 7.2e-36 123.3 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain UCH PF00443.29 EMC94404.1 - 4.7e-48 163.9 0.0 6.8e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC94404.1 - 3.5e-11 43.3 12.9 4.1e-06 26.6 9.1 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EMC94404.1 - 3.9e-09 36.1 0.0 9.8e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family LYRIC PF15686.5 EMC94404.1 - 0.063 12.8 16.0 0.1 12.2 16.0 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Ubiquitin_2 PF14560.6 EMC94404.1 - 0.13 12.8 0.1 0.42 11.1 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin-like domain DNA_methylase PF00145.17 EMC94405.1 - 9.3e-47 160.0 0.0 3.4e-36 125.3 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_6 PF13522.6 EMC94407.1 - 5.8e-15 55.7 0.0 2.3e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EMC94407.1 - 5.6e-13 48.9 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EMC94407.1 - 9.6e-07 28.4 0.0 2.7e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EMC94407.1 - 1.5e-05 24.0 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Abhydrolase_6 PF12697.7 EMC94408.1 - 1.1e-05 26.2 0.0 1.5e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC94408.1 - 0.0055 16.4 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LUD_dom PF02589.15 EMC94408.1 - 0.03 14.1 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 LUD domain Glucosamine_iso PF01182.20 EMC94410.1 - 2.9e-70 236.7 0.0 3.2e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GMC_oxred_N PF00732.19 EMC94411.1 - 1.6e-50 172.2 0.0 2.1e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC94411.1 - 2.7e-31 109.0 0.0 6.5e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMC94411.1 - 3.1e-08 33.1 4.2 0.00069 18.8 1.0 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EMC94411.1 - 4.5e-06 26.5 1.0 0.00045 19.9 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC94411.1 - 0.00078 19.6 2.7 0.0028 17.8 2.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMC94411.1 - 0.0015 17.8 0.3 0.21 10.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC94411.1 - 0.0026 16.7 0.1 0.0039 16.1 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 EMC94411.1 - 0.0043 16.3 0.6 0.009 15.3 0.5 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMC94411.1 - 0.013 14.6 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EMC94411.1 - 0.19 10.7 1.1 1.2 8.1 1.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMC94411.1 - 2.6 7.3 4.6 4.3 6.6 3.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase CorA PF01544.18 EMC94412.1 - 7.9e-11 41.8 0.9 1.1e-10 41.3 0.9 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoL PF05461.11 EMC94412.1 - 0.14 11.5 2.7 0.31 10.3 2.1 1.7 1 1 1 2 2 2 0 Apolipoprotein L partial_CstF PF15861.5 EMC94412.1 - 0.29 10.9 1.5 0.46 10.3 0.2 1.9 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain RHH_3 PF12651.7 EMC94412.1 - 0.8 9.7 3.1 1.3 9.0 0.3 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain F-box-like PF12937.7 EMC94413.1 - 0.014 15.3 0.1 0.034 14.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like RPA_C PF08784.11 EMC94414.1 - 0.09 13.4 0.0 0.26 12.0 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal Ribosomal_S30 PF04758.14 EMC94415.1 - 3.2e-30 104.1 10.1 3.5e-30 104.0 10.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pyrid_oxidase_2 PF13883.6 EMC94416.1 - 1.4e-35 122.7 0.0 5.2e-35 120.9 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4380 PF14315.6 EMC94416.1 - 0.007 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4380) PAN_1 PF00024.26 EMC94417.1 - 1.3e-10 41.1 23.6 3.2e-07 30.2 0.3 5.9 5 0 0 5 5 5 3 PAN domain PAN_3 PF08277.12 EMC94417.1 - 8.9e-05 22.2 13.8 0.15 11.9 0.3 4.7 4 0 0 4 4 4 3 PAN-like domain STb_secrete PF09075.10 EMC94417.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory PAN_4 PF14295.6 EMC94417.1 - 3.9 7.5 29.6 1.8 8.6 0.3 4.9 5 0 0 5 5 5 0 PAN domain SET PF00856.28 EMC94418.1 - 6.5e-15 55.9 0.0 2.4e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 SET domain ApbA PF02558.16 EMC94420.1 - 1.2e-24 86.7 0.0 1.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EMC94420.1 - 1.8e-21 76.6 0.0 2.7e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal His_Phos_1 PF00300.22 EMC94421.1 - 1.6e-35 122.5 2.0 2.6e-33 115.4 2.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.24 EMC94422.1 - 4.6e-80 269.7 20.1 5.9e-80 269.3 20.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC94422.1 - 2.6e-24 85.8 31.0 2.6e-24 85.8 31.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC94422.1 - 6.7e-08 31.4 2.8 1.1e-07 30.7 2.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMC94423.1 - 1.2e-60 205.6 9.4 1.4e-60 205.5 9.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC94423.1 - 6.5e-08 31.9 35.4 2.1e-06 26.9 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_A24 PF01478.18 EMC94423.1 - 0.36 11.3 6.3 0.3 11.5 0.3 2.3 2 0 0 2 2 2 0 Type IV leader peptidase family PRA1 PF03208.19 EMC94423.1 - 4.7 6.8 9.9 6.1 6.5 8.2 2.2 2 1 0 2 2 2 0 PRA1 family protein DUF1479 PF07350.12 EMC94424.1 - 4.8e-127 424.2 0.0 5.6e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EMC94424.1 - 0.017 15.4 0.1 1.1 9.5 0.1 2.4 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) CorA PF01544.18 EMC94425.1 - 9.9e-12 44.8 0.2 1.3e-11 44.4 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 EMC94425.1 - 0.013 14.3 0.1 0.024 13.4 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DASH_Hsk3 PF08227.11 EMC94427.1 - 4.7e-19 68.5 3.3 7.2e-19 67.9 3.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF3138 PF11336.8 EMC94427.1 - 0.08 11.5 1.9 0.088 11.4 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BBS2_C PF14782.6 EMC94427.1 - 0.084 11.6 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Memo PF01875.17 EMC94428.1 - 3.8e-68 229.6 0.0 4.7e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein IBR PF01485.21 EMC94429.1 - 4.4e-05 23.6 2.8 4.4e-05 23.6 2.8 2.8 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Fe-ADH PF00465.19 EMC94430.1 - 8.2e-78 261.7 0.0 9.6e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMC94430.1 - 6.4e-13 49.0 0.0 8.4e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Na_H_Exchanger PF00999.21 EMC94431.1 - 1.3e-61 208.5 49.4 1.7e-61 208.1 49.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3336 PF11815.8 EMC94433.1 - 6.3e-31 106.9 0.5 1.2e-30 106.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EMC94433.1 - 3.5e-22 79.6 0.0 7.4e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_S51 PF03575.17 EMC94433.1 - 0.17 11.5 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S51 PAN_4 PF14295.6 EMC94434.1 - 0.017 15.0 1.1 0.028 14.3 1.1 1.5 1 0 0 1 1 1 0 PAN domain WD40 PF00400.32 EMC94435.1 - 7.7e-19 67.7 10.5 0.00071 20.3 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC94435.1 - 3.3e-15 56.1 0.0 8.7e-06 26.0 0.0 4.6 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMC94435.1 - 5.8e-06 26.3 0.2 0.014 15.3 0.0 3.8 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 EMC94435.1 - 0.011 14.5 0.1 13 4.5 0.1 4.0 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 EMC94435.1 - 0.073 13.0 6.3 7.4 6.6 0.1 4.3 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EMC94435.1 - 0.22 10.4 0.0 8 5.3 0.0 2.6 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PhoLip_ATPase_C PF16212.5 EMC94436.1 - 3.6e-79 266.0 27.0 3.6e-79 266.0 27.0 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMC94436.1 - 2.1e-19 68.9 0.1 7.5e-19 67.2 0.1 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EMC94436.1 - 4.7e-12 46.6 3.1 8.3e-07 29.5 2.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMC94436.1 - 7.4e-11 42.0 0.0 3.3e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EMC94436.1 - 0.00013 21.5 0.0 0.00013 21.5 0.0 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EMC94436.1 - 0.0058 16.4 0.2 0.024 14.4 0.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TED_complement PF07678.14 EMC94438.1 - 0.055 12.5 0.1 0.086 11.9 0.1 1.2 1 0 0 1 1 1 0 A-macroglobulin TED domain HemY_N PF07219.13 EMC94438.1 - 0.32 11.2 4.3 0.51 10.6 0.0 2.7 2 0 0 2 2 2 0 HemY protein N-terminus vATP-synt_E PF01991.18 EMC94439.1 - 1.2e-58 197.9 8.7 1.4e-58 197.6 8.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Tox-MPTase4 PF15640.6 EMC94439.1 - 0.011 15.6 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 Metallopeptidase toxin 4 DUF2196 PF09962.9 EMC94440.1 - 1.1e-23 82.9 2.7 1.7e-23 82.4 2.7 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) MA3 PF02847.17 EMC94441.1 - 3.1e-25 88.3 0.1 1.3e-24 86.3 0.0 2.2 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EMC94441.1 - 6e-10 39.1 1.0 1.2e-09 38.1 1.0 1.5 1 0 0 1 1 1 1 MIF4G domain Cnd1 PF12717.7 EMC94441.1 - 0.016 15.2 2.3 0.048 13.7 2.3 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 CNOT1_TTP_bind PF16417.5 EMC94441.1 - 0.36 10.0 0.0 0.36 10.0 0.0 2.6 3 1 0 3 3 3 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Abhydrolase_2 PF02230.16 EMC94442.1 - 7.5e-29 101.1 0.0 1.1e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EMC94442.1 - 0.0061 17.2 0.1 0.76 10.3 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family GAD-like PF08887.11 EMC94442.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 GAD-like domain DLH PF01738.18 EMC94442.1 - 0.024 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EMC94442.1 - 0.036 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EMC94442.1 - 0.044 13.0 0.5 6.8 5.9 0.0 2.9 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EMC94442.1 - 0.15 11.6 0.0 0.78 9.2 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase ANAPC4_WD40 PF12894.7 EMC94443.1 - 6.6e-05 23.1 0.1 0.0029 17.9 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMC94443.1 - 0.0036 18.1 2.1 4.6 8.3 0.1 4.0 3 1 0 3 3 3 2 WD domain, G-beta repeat LisH PF08513.11 EMC94443.1 - 0.15 12.0 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 LisH Cu-oxidase_2 PF07731.14 EMC94445.1 - 4.7e-20 71.7 2.8 3.8e-18 65.5 1.3 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMC94445.1 - 2.6e-15 56.5 2.0 1.1e-14 54.5 0.8 2.6 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EMC94445.1 - 5.7e-05 23.3 3.6 0.00028 21.0 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.16 EMC94446.1 - 9.9e-39 133.2 27.8 9.9e-39 133.2 27.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily VanZ PF04892.12 EMC94446.1 - 0.0029 18.3 0.8 0.013 16.1 0.8 2.2 1 0 0 1 1 1 1 VanZ like family CcmD PF04995.14 EMC94446.1 - 0.015 15.4 0.3 0.046 13.8 0.3 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF202 PF02656.15 EMC94446.1 - 8.3 6.9 9.7 7.1 7.2 0.3 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF1690 PF07956.11 EMC94447.1 - 3.7e-35 121.4 11.9 2.2e-34 118.8 11.9 1.8 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 EMC94447.1 - 0.029 14.4 2.7 0.029 14.4 2.7 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Acetyltransf_1 PF00583.25 EMC94448.1 - 5.9e-11 42.6 0.0 8.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC94448.1 - 6.2e-05 23.3 0.0 0.0001 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC94448.1 - 6.4e-05 22.9 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EMC94448.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.7 EMC94448.1 - 0.097 12.8 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC94448.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein adh_short PF00106.25 EMC94450.1 - 2e-45 154.7 0.1 2.6e-45 154.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC94450.1 - 1e-28 100.5 0.1 1.3e-28 100.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC94450.1 - 0.00019 21.4 0.1 0.00028 20.8 0.1 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EMC94450.1 - 0.0089 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EMC94450.1 - 0.035 13.6 0.0 0.084 12.3 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Metallophos PF00149.28 EMC94451.1 - 2.1e-40 139.4 0.1 2.6e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMC94451.1 - 9.7e-23 80.4 2.1 1.3e-22 79.9 1.3 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 EMC94452.1 - 1.9e-24 85.5 12.6 9.4e-07 29.4 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC94452.1 - 1.3e-13 51.1 2.1 2.5e-05 24.5 0.1 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMC94452.1 - 0.031 13.3 0.0 0.081 11.9 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 EMC94452.1 - 0.047 12.3 0.0 0.09 11.4 0.0 1.4 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin TDRP PF15683.5 EMC94454.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Testis development-related protein DUF4802 PF16060.5 EMC94454.1 - 5.7 7.2 7.0 2.3 8.4 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4802) LRR_4 PF12799.7 EMC94455.1 - 3.3e-12 46.4 5.2 8.3e-06 26.1 0.3 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMC94455.1 - 4.4e-11 42.4 7.0 1.8e-08 34.0 1.1 3.5 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 EMC94455.1 - 8.5e-06 25.4 5.3 10 6.5 0.0 5.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.6 EMC94455.1 - 4.4e-05 23.1 1.8 0.00017 21.1 1.0 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EMC94455.1 - 0.00021 21.4 5.1 9.4 7.2 0.0 5.8 5 0 0 5 5 5 1 Leucine Rich Repeat Xpo1 PF08389.12 EMC94456.1 - 8.1e-32 110.3 3.2 1e-30 106.8 0.0 4.0 4 1 0 4 4 4 1 Exportin 1-like protein TRP PF06011.12 EMC94456.1 - 0.073 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel HTH_22 PF13309.6 EMC94456.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 HTH domain HEAT PF02985.22 EMC94456.1 - 0.44 10.9 5.2 5.2 7.6 0.0 4.8 6 0 0 6 6 6 0 HEAT repeat UME PF08064.13 EMC94458.1 - 0.049 13.6 0.2 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 UME (NUC010) domain DUF4201 PF13870.6 EMC94458.1 - 0.051 13.3 1.4 0.093 12.5 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) MIS13 PF08202.11 EMC94458.1 - 0.062 12.6 2.2 0.081 12.2 0.8 1.8 1 1 0 2 2 2 0 Mis12-Mtw1 protein family Ribosomal_S8 PF00410.19 EMC94460.1 - 7.4e-14 51.8 0.0 8.1e-08 32.3 0.0 2.9 2 1 0 2 2 2 2 Ribosomal protein S8 DUF5321 PF17254.2 EMC94461.1 - 1.8e-58 196.5 4.1 2.2e-58 196.2 4.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF1654 PF07867.11 EMC94461.1 - 0.035 13.8 0.4 0.08 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Moulting_cycle PF04870.16 EMC94461.1 - 0.064 12.5 3.8 0.079 12.2 3.8 1.2 1 0 0 1 1 1 0 Moulting cycle CDC45 PF02724.14 EMC94461.1 - 0.41 8.9 5.5 0.49 8.6 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein MRP-S26 PF14943.6 EMC94461.1 - 0.84 9.5 12.3 1.2 9.1 12.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Oxysterol_BP PF01237.18 EMC94461.1 - 3.2 6.5 7.0 4.1 6.1 7.0 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein ADIP PF11559.8 EMC94462.1 - 4.3e-09 36.6 24.6 1.1e-05 25.6 13.0 1.9 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 EMC94462.1 - 2.2e-05 24.7 10.0 0.0062 16.8 1.5 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) DUF1664 PF07889.12 EMC94462.1 - 3.3e-05 23.9 5.8 3.3e-05 23.9 5.8 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) YabA PF06156.13 EMC94462.1 - 0.00079 20.0 8.9 0.0041 17.7 1.1 2.1 1 1 1 2 2 2 1 Initiation control protein YabA KASH_CCD PF14662.6 EMC94462.1 - 0.0011 18.9 9.4 0.0025 17.7 4.0 1.8 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 EMC94462.1 - 0.0013 18.9 6.6 0.0025 18.1 6.6 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 EMC94462.1 - 0.003 17.5 3.8 0.014 15.4 0.5 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 EMC94462.1 - 0.0046 17.2 10.9 0.063 13.6 6.0 2.5 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.6 EMC94462.1 - 0.0046 16.7 9.9 0.016 15.0 4.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 EMC94462.1 - 0.0074 16.4 5.1 0.0074 16.4 5.1 2.1 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 EMC94462.1 - 0.0077 15.5 7.5 0.0093 15.2 7.5 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF3450 PF11932.8 EMC94462.1 - 0.0081 15.5 16.4 0.041 13.2 5.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Troponin PF00992.20 EMC94462.1 - 0.0082 16.4 0.8 0.019 15.2 0.8 1.7 1 1 0 1 1 1 1 Troponin Spc7 PF08317.11 EMC94462.1 - 0.0088 15.0 5.2 0.011 14.7 5.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein APG6_N PF17675.1 EMC94462.1 - 0.0089 16.6 4.0 0.013 16.0 4.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region AAA_13 PF13166.6 EMC94462.1 - 0.0097 14.6 4.0 0.012 14.3 4.0 1.0 1 0 0 1 1 1 1 AAA domain TMPIT PF07851.13 EMC94462.1 - 0.011 15.0 3.0 0.015 14.6 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein GNT-I PF03071.15 EMC94462.1 - 0.022 13.6 1.7 0.025 13.4 1.7 1.1 1 0 0 1 1 1 0 GNT-I family Vip3A_N PF12495.8 EMC94462.1 - 0.025 14.5 3.2 0.031 14.2 3.2 1.1 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal HrpB7 PF09486.10 EMC94462.1 - 0.027 14.8 8.8 0.039 14.3 8.8 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Myosin_tail_1 PF01576.19 EMC94462.1 - 0.028 12.2 4.6 0.032 12.0 4.6 1.0 1 0 0 1 1 1 0 Myosin tail ERM PF00769.19 EMC94462.1 - 0.029 14.2 4.9 0.046 13.5 4.9 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family bZIP_1 PF00170.21 EMC94462.1 - 0.031 14.4 1.1 1.7 8.8 0.0 3.1 2 1 2 4 4 4 0 bZIP transcription factor TACC_C PF05010.14 EMC94462.1 - 0.033 14.0 3.4 0.04 13.7 3.4 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Leu_zip PF15294.6 EMC94462.1 - 0.034 13.7 5.8 0.093 12.2 5.6 1.4 1 1 1 2 2 2 0 Leucine zipper Not3 PF04065.15 EMC94462.1 - 0.035 13.5 4.1 0.055 12.9 4.1 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Filament PF00038.21 EMC94462.1 - 0.044 13.4 6.8 0.063 12.8 6.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein HMMR_N PF15905.5 EMC94462.1 - 0.044 13.2 7.7 0.059 12.8 7.7 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1640 PF07798.11 EMC94462.1 - 0.057 13.5 5.3 2.4 8.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) V_ATPase_I PF01496.19 EMC94462.1 - 0.059 11.3 2.5 0.073 11.0 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TSNAXIP1_N PF15739.5 EMC94462.1 - 0.059 13.7 5.6 1 9.8 0.7 2.1 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus EzrA PF06160.12 EMC94462.1 - 0.063 11.4 5.0 0.11 10.7 5.0 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF737 PF05300.11 EMC94462.1 - 0.067 13.5 1.4 0.13 12.6 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Atg14 PF10186.9 EMC94462.1 - 0.079 12.0 4.7 0.098 11.7 4.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Wtap PF17098.5 EMC94462.1 - 0.082 12.8 4.0 1.7 8.6 0.1 2.1 1 1 0 2 2 2 0 WTAP/Mum2p family Phage_GPO PF05929.11 EMC94462.1 - 0.083 12.5 2.6 0.12 12.0 2.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase LPP PF04728.13 EMC94462.1 - 0.089 13.2 15.8 3.8 8.0 5.0 3.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper D-ser_dehydrat PF14031.6 EMC94462.1 - 0.092 13.4 0.6 0.18 12.5 0.6 1.7 1 1 0 1 1 1 0 Putative serine dehydratase domain MbeD_MobD PF04899.12 EMC94462.1 - 0.098 12.8 14.2 0.55 10.4 0.4 3.3 1 1 2 3 3 3 0 MbeD/MobD like DUF4686 PF15742.5 EMC94462.1 - 0.12 11.5 14.0 0.19 10.8 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) COG6 PF06419.11 EMC94462.1 - 0.12 10.5 8.0 0.11 10.7 6.7 1.5 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 GAS PF13851.6 EMC94462.1 - 0.13 11.6 8.0 2.4 7.4 2.3 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HMMR_C PF15908.5 EMC94462.1 - 0.13 12.5 6.8 3 8.1 0.5 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Tnp_DNA_bind PF14706.6 EMC94462.1 - 0.14 12.1 2.3 2.3 8.2 0.1 3.0 2 1 1 3 3 3 0 Transposase DNA-binding TMCO5 PF14992.6 EMC94462.1 - 0.14 11.7 5.5 0.26 10.8 5.5 1.4 1 1 0 1 1 1 0 TMCO5 family ZapB PF06005.12 EMC94462.1 - 0.15 12.5 14.6 0.43 11.1 3.1 2.5 1 1 1 2 2 2 0 Cell division protein ZapB DUF4472 PF14739.6 EMC94462.1 - 0.16 12.7 5.6 0.13 13.0 3.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) COG5 PF10392.9 EMC94462.1 - 0.17 12.1 6.5 7.7 6.7 6.2 2.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 SHE3 PF17078.5 EMC94462.1 - 0.18 11.5 8.7 2.5 7.8 8.8 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 TMF_TATA_bd PF12325.8 EMC94462.1 - 0.18 12.0 7.5 0.56 10.4 7.5 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cluap1 PF10234.9 EMC94462.1 - 0.18 11.1 7.0 0.28 10.5 7.0 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 COG2 PF06148.11 EMC94462.1 - 0.19 11.8 6.1 0.19 11.8 4.4 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HOOK PF05622.12 EMC94462.1 - 0.19 9.8 9.1 0.24 9.5 9.1 1.0 1 0 0 1 1 1 0 HOOK protein YlqD PF11068.8 EMC94462.1 - 0.21 12.0 17.7 9.7 6.6 17.7 2.1 1 1 0 1 1 1 0 YlqD protein JIP_LZII PF16471.5 EMC94462.1 - 0.21 11.8 6.8 5.1 7.4 2.0 2.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Tropomyosin_1 PF12718.7 EMC94462.1 - 0.24 11.6 6.9 0.64 10.2 6.7 1.8 1 1 0 1 1 1 0 Tropomyosin like APG17 PF04108.12 EMC94462.1 - 0.26 10.4 9.3 0.92 8.6 2.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF724 PF05266.14 EMC94462.1 - 0.26 11.1 3.3 0.67 9.8 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) NPV_P10 PF05531.12 EMC94462.1 - 0.27 11.7 16.2 0.9 10.1 3.0 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4618 PF15397.6 EMC94462.1 - 0.32 10.4 10.2 2.8 7.3 2.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 EMC94462.1 - 0.4 11.1 5.4 15 6.0 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BRE1 PF08647.11 EMC94462.1 - 0.43 10.7 7.6 2.1 8.5 7.6 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase CLZ PF16526.5 EMC94462.1 - 0.47 10.9 8.2 4.2 7.8 2.3 2.8 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lzipper-MIP1 PF14389.6 EMC94462.1 - 0.52 10.6 6.3 0.53 10.6 0.2 3.0 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Imm7 PF15585.6 EMC94462.1 - 0.56 10.5 4.5 0.63 10.3 1.7 2.0 1 1 1 2 2 2 0 Immunity protein 7 TSC22 PF01166.18 EMC94462.1 - 0.59 10.5 6.5 1.3 9.4 0.3 3.2 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF4407 PF14362.6 EMC94462.1 - 0.68 9.2 14.1 6.6 6.0 13.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CC2-LZ PF16516.5 EMC94462.1 - 0.7 10.3 7.4 0.63 10.4 3.4 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc24 PF08286.11 EMC94462.1 - 0.73 10.1 8.1 1.9 8.7 5.8 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-H PF05837.12 EMC94462.1 - 0.81 10.1 9.5 2.4 8.6 9.5 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) PspA_IM30 PF04012.12 EMC94462.1 - 0.9 9.1 13.1 0.4 10.2 1.8 2.2 1 1 1 2 2 2 0 PspA/IM30 family Rootletin PF15035.6 EMC94462.1 - 0.97 9.4 13.2 3.1 7.8 13.2 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FUSC PF04632.12 EMC94462.1 - 0.99 7.9 5.3 1.1 7.7 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF812 PF05667.11 EMC94462.1 - 1 8.2 9.7 5.6 5.7 9.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Prominin PF05478.11 EMC94462.1 - 1.1 7.2 6.8 1.4 6.8 6.8 1.1 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.12 EMC94462.1 - 1.1 9.3 9.3 1.5 8.9 6.3 1.9 1 1 0 1 1 1 0 Laminin Domain II SseC PF04888.12 EMC94462.1 - 1.2 8.7 7.0 0.22 11.1 1.8 1.8 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family DivIC PF04977.15 EMC94462.1 - 1.2 8.9 15.6 4.8 7.0 5.0 3.0 1 1 2 3 3 3 0 Septum formation initiator DUF4763 PF15960.5 EMC94462.1 - 1.3 8.3 15.8 2.3 7.4 6.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF4795 PF16043.5 EMC94462.1 - 1.3 8.6 11.5 1.7 8.2 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF1759 PF03564.15 EMC94462.1 - 1.4 8.9 4.1 9.3 6.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) SlyX PF04102.12 EMC94462.1 - 1.4 9.6 20.5 3.9 8.2 7.1 3.1 1 1 2 3 3 3 0 SlyX IFT57 PF10498.9 EMC94462.1 - 1.5 7.7 10.0 2.6 6.9 10.0 1.3 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 FAM76 PF16046.5 EMC94462.1 - 1.6 8.0 4.5 2.7 7.3 4.5 1.4 1 0 0 1 1 1 0 FAM76 protein PRKG1_interact PF15898.5 EMC94462.1 - 1.6 9.7 7.1 19 6.2 5.0 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain CorA PF01544.18 EMC94462.1 - 1.7 7.9 7.3 2.7 7.2 7.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sec34 PF04136.15 EMC94462.1 - 1.7 8.5 8.1 1 9.2 2.4 2.0 1 1 1 2 2 2 0 Sec34-like family DASH_Dad4 PF08650.10 EMC94462.1 - 1.8 8.6 6.8 25 4.9 0.2 3.0 1 1 0 2 2 2 0 DASH complex subunit Dad4 DUF948 PF06103.11 EMC94462.1 - 1.8 8.8 14.9 3.3 8.0 3.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fungal_TACC PF12709.7 EMC94462.1 - 2 8.9 6.7 5.1 7.6 1.5 2.7 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins FlaC_arch PF05377.11 EMC94462.1 - 2.1 8.8 6.0 8.4 6.9 2.3 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 EMC94462.1 - 2.2 8.4 13.8 2 8.6 0.5 4.1 2 1 2 4 4 4 0 Basic region leucine zipper Trimer_CC PF08954.11 EMC94462.1 - 2.2 7.9 9.0 0.17 11.5 2.3 2.6 3 1 1 4 4 2 0 Trimerisation motif FlxA PF14282.6 EMC94462.1 - 2.4 8.2 23.0 1.7e+02 2.2 23.0 2.3 1 1 0 1 1 1 0 FlxA-like protein DUF2203 PF09969.9 EMC94462.1 - 2.5 8.8 6.7 2.9 8.6 1.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cnn_1N PF07989.11 EMC94462.1 - 2.7 8.2 8.2 2.6 8.3 0.4 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 HemX PF04375.14 EMC94462.1 - 3.7 6.7 18.2 1.4 8.1 5.5 1.9 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Csm1_N PF18504.1 EMC94462.1 - 4.3 7.7 12.6 16 5.9 0.5 3.1 1 1 2 3 3 3 0 Csm1 N-terminal domain Macoilin PF09726.9 EMC94462.1 - 4.4 5.8 8.4 7.7 4.9 8.4 1.4 1 1 0 1 1 1 0 Macoilin family Syntaxin_2 PF14523.6 EMC94462.1 - 4.4 7.7 13.3 2.2 8.7 7.8 2.2 1 1 1 2 2 2 0 Syntaxin-like protein ABC_tran_CTD PF16326.5 EMC94462.1 - 4.7 7.5 7.9 19 5.6 0.5 2.3 1 1 0 2 2 2 0 ABC transporter C-terminal domain FliJ PF02050.16 EMC94462.1 - 5.9 7.1 17.9 14 5.9 1.4 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein Fib_alpha PF08702.10 EMC94462.1 - 9.5 6.4 17.3 2.4 8.3 11.6 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family LtrA PF06772.11 EMC94464.1 - 9.1e-41 140.2 28.4 9.1e-41 140.2 28.4 1.7 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DUF2715 PF10895.8 EMC94464.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) Vps5 PF09325.10 EMC94465.1 - 9.8e-83 277.3 0.5 1.5e-82 276.7 0.5 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EMC94465.1 - 1.1e-25 89.8 0.1 2.4e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 EMC94465.1 - 0.012 15.1 1.0 0.13 11.7 0.2 2.4 1 1 2 3 3 3 0 WASP-binding domain of Sorting nexin protein CorA PF01544.18 EMC94465.1 - 0.12 11.7 2.9 0.061 12.6 0.4 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein XRN_M PF17846.1 EMC94465.1 - 0.28 10.1 2.1 0.52 9.2 2.1 1.3 1 0 0 1 1 1 0 Xrn1 helical domain DUF5315 PF17242.2 EMC94465.1 - 3.2 7.6 10.5 2.6 7.9 2.4 2.4 1 1 1 2 2 2 0 Disordered region of unknown function (DUF5315) HET PF06985.11 EMC94466.1 - 4.7e-25 88.6 0.0 7.8e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_64 PF16483.5 EMC94467.1 - 4.6e-127 424.3 0.6 5.5e-127 424.1 0.6 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase SQS_PSY PF00494.19 EMC94468.1 - 4.3e-35 121.5 0.0 5.8e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Rhodanese PF00581.20 EMC94470.1 - 8e-14 52.1 0.0 1.1e-06 29.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PK PF00224.21 EMC94471.1 - 7.3e-172 571.0 5.5 8.9e-172 570.7 5.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EMC94471.1 - 4.7e-38 130.0 0.0 1.7e-37 128.3 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EMC94471.1 - 0.00051 19.2 0.3 0.0015 17.7 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EMC94471.1 - 0.074 12.0 0.0 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.10 EMC94472.1 - 5.7e-29 99.8 0.0 6.4e-29 99.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) GAS PF13851.6 EMC94473.1 - 0.071 12.5 2.7 1.8 7.9 0.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Hemerythrin PF01814.23 EMC94473.1 - 0.072 13.7 5.2 1.4 9.5 0.9 2.6 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain M PF02370.16 EMC94473.1 - 0.14 12.8 1.5 0.14 12.8 1.5 2.4 3 0 0 3 3 3 0 M protein repeat APG6_N PF17675.1 EMC94473.1 - 0.14 12.7 3.5 0.24 11.9 3.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 EMC94473.1 - 0.83 9.9 4.5 0.81 10.0 0.9 2.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper PSDC PF12588.8 EMC94475.1 - 1.6e-59 199.9 0.0 2.4e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EMC94475.1 - 7.4e-39 133.4 0.0 1.4e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EMC94475.1 - 0.0015 18.3 0.3 0.23 11.3 0.2 2.3 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EMC94475.1 - 0.012 15.5 0.0 0.53 10.2 0.1 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme PALP PF00291.25 EMC94476.1 - 7.7e-76 255.3 1.4 7.7e-76 255.3 1.4 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EMC94476.1 - 9.2e-42 140.7 0.0 2.1e-20 72.3 0.0 2.2 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Mg_trans_NIPA PF05653.14 EMC94476.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA PTAC PF06130.12 EMC94476.1 - 0.19 11.9 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphate propanoyltransferase HIG_1_N PF04588.13 EMC94477.1 - 3.6e-22 78.3 0.0 5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region TMF_TATA_bd PF12325.8 EMC94479.1 - 0.0047 17.1 1.1 0.0058 16.8 1.1 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 EMC94479.1 - 0.022 14.8 0.2 0.026 14.6 0.2 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase ESAG1 PF03238.13 EMC94479.1 - 0.032 13.7 0.0 0.057 12.9 0.0 1.3 1 1 0 1 1 1 0 ESAG protein Cep57_CLD_2 PF14197.6 EMC94479.1 - 0.043 13.9 2.0 0.093 12.8 2.0 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Hydrolase_4 PF12146.8 EMC94480.1 - 6.2e-52 176.2 0.0 7.4e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMC94480.1 - 1.9e-13 51.5 0.9 2.5e-13 51.1 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC94480.1 - 7.3e-08 32.4 0.1 1.2e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 EMC94480.1 - 0.017 14.2 0.0 0.037 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) PAF-AH_p_II PF03403.13 EMC94480.1 - 0.05 12.1 1.1 3.3 6.1 0.3 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 EMC94480.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Myb_DNA-bind_4 PF13837.6 EMC94482.1 - 0.093 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC94482.1 - 0.16 12.3 0.1 1.3 9.3 0.0 2.4 2 1 1 3 3 3 0 Myb-like DNA-binding domain DUF3336 PF11815.8 EMC94483.1 - 1e-51 174.3 1.6 1.7e-51 173.6 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EMC94483.1 - 2.2e-17 63.9 0.1 1.4e-16 61.3 0.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase NAD_binding_1 PF00175.21 EMC94484.1 - 5.8e-08 33.4 0.0 0.00061 20.4 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMC94484.1 - 4.6e-07 30.1 0.0 0.00019 21.6 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EMC94484.1 - 0.19 12.1 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain AAA PF00004.29 EMC94486.1 - 6.3e-21 75.2 0.0 1e-20 74.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EMC94486.1 - 0.0002 21.0 0.0 0.00063 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMC94486.1 - 0.00062 19.8 0.0 0.0048 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 EMC94486.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 KaiC RuvB_N PF05496.12 EMC94486.1 - 0.0024 17.6 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IPT PF01745.16 EMC94486.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase RNA_helicase PF00910.22 EMC94486.1 - 0.013 15.9 0.0 0.1 13.0 0.0 2.4 3 1 1 4 4 2 0 RNA helicase AAA_16 PF13191.6 EMC94486.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EMC94486.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMC94486.1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMC94486.1 - 0.024 14.9 0.0 0.065 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMC94486.1 - 0.029 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EMC94486.1 - 0.034 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 EMC94486.1 - 0.036 14.6 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMC94486.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EMC94486.1 - 0.076 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 EMC94486.1 - 0.12 12.8 0.4 0.28 11.6 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_6 PF12774.7 EMC94486.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 EMC94486.1 - 0.17 12.1 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EMC94486.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 EMC94486.1 - 0.21 10.4 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase ATG16 PF08614.11 EMC94488.1 - 0.0067 16.7 9.5 0.0067 16.7 9.5 3.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Raf1_HTH PF18579.1 EMC94488.1 - 0.068 12.9 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Tropomyosin_1 PF12718.7 EMC94488.1 - 0.11 12.6 15.3 0.15 12.2 14.2 1.9 1 1 0 1 1 1 0 Tropomyosin like KELK PF15796.5 EMC94488.1 - 0.26 11.8 15.2 0.35 11.3 9.2 3.0 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase bZIP_2 PF07716.15 EMC94488.1 - 4.1 7.6 8.5 0.78 9.9 1.3 3.1 3 1 0 3 3 3 0 Basic region leucine zipper Laminin_II PF06009.12 EMC94488.1 - 4.4 7.3 11.9 9.9 6.2 7.6 2.3 2 0 0 2 2 2 0 Laminin Domain II Spc24 PF08286.11 EMC94488.1 - 6.9 7.0 15.6 4.1 7.7 6.6 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 ADIP PF11559.8 EMC94488.1 - 8.2 6.5 20.3 10 6.2 13.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GFA PF04828.14 EMC94489.1 - 9.2e-14 51.6 2.1 1.5e-13 50.9 2.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme IBR PF01485.21 EMC94490.1 - 0.00028 21.0 15.2 0.0013 18.9 5.5 2.8 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-UBP PF02148.19 EMC94490.1 - 0.78 10.1 5.0 2 8.8 4.8 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein ANAPC4_WD40 PF12894.7 EMC94491.1 - 1.7e-07 31.4 0.0 0.0021 18.3 0.0 3.1 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMC94491.1 - 0.00015 22.5 10.7 1.1 10.2 0.1 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat YL1 PF05764.13 EMC94491.1 - 0.015 15.5 7.7 0.021 14.9 7.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RR_TM4-6 PF06459.12 EMC94491.1 - 0.043 13.6 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TLP-20 PF06088.11 EMC94491.1 - 0.13 12.2 0.7 0.21 11.5 0.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Cnd2 PF05786.14 EMC94491.1 - 0.18 10.5 7.4 0.25 9.9 7.4 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 CDC45 PF02724.14 EMC94491.1 - 0.23 9.7 6.1 0.32 9.2 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EMC94491.1 - 1.7 7.1 3.1 2.2 6.7 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 EMC94491.1 - 1.8 7.8 7.3 2.9 7.1 7.3 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EMC94491.1 - 2.3 6.3 7.7 3.1 5.9 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 EMC94491.1 - 2.8 8.4 12.1 5.8 7.3 12.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FmiP_Thoc5 PF09766.9 EMC94491.1 - 7.1 5.8 4.7 10 5.3 4.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Raffinose_syn PF05691.12 EMC94492.1 - 2.3e-55 187.8 0.3 3.1e-50 170.8 1.3 3.4 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.26 EMC94492.1 - 4.8e-05 22.7 0.9 7.2e-05 22.1 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 EMC94492.1 - 0.002 17.1 0.9 0.0034 16.4 0.9 1.2 1 0 0 1 1 1 1 Melibiase F-box PF00646.33 EMC94493.1 - 0.034 14.1 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 F-box domain Pmp3 PF01679.17 EMC94494.1 - 2.9e-15 56.2 9.3 4e-15 55.8 9.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator LSM PF01423.22 EMC94495.1 - 4.2e-12 45.6 0.0 4.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMC94495.1 - 0.0017 18.5 0.0 0.0026 17.9 0.0 1.4 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF4227 PF14004.6 EMC94495.1 - 0.086 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) NEAT PF05031.12 EMC94495.1 - 0.1 13.2 0.0 0.17 12.5 0.0 1.5 1 1 0 1 1 1 0 Iron Transport-associated domain DUF2264 PF10022.9 EMC94496.1 - 7e-136 452.9 0.2 8.6e-136 452.7 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) PIG-S PF10510.9 EMC94498.1 - 8e-151 503.3 0.0 9.1e-151 503.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Acyl-CoA_dh_1 PF00441.24 EMC94499.1 - 6.8e-41 140.0 1.2 1e-40 139.4 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMC94499.1 - 1.1e-21 76.8 0.3 1.9e-21 76.0 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EMC94499.1 - 3.8e-21 75.0 0.1 7.5e-21 74.1 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EMC94499.1 - 6.7e-18 65.4 0.0 1.6e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMC94499.1 - 1.9e-07 31.5 0.1 3.2e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 EMC94499.1 - 0.12 12.9 0.1 0.88 10.1 0.0 2.4 2 1 1 3 3 3 0 C6 domain Med8 PF10232.9 EMC94500.1 - 4e-30 105.1 0.0 7.3e-30 104.3 0.0 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 NOA36 PF06524.12 EMC94500.1 - 1 8.6 3.0 1.3 8.2 3.0 1.2 1 0 0 1 1 1 0 NOA36 protein Peptidase_S15 PF02129.18 EMC94501.1 - 0.02 14.5 0.5 0.13 11.9 0.0 2.2 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EMC94501.1 - 0.066 12.8 0.5 20 4.7 0.1 3.0 3 1 0 3 3 3 0 alpha/beta hydrolase fold Cyclin_N PF00134.23 EMC94503.1 - 9.9e-35 119.1 0.5 1.7e-34 118.3 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMC94503.1 - 7.1e-13 48.7 2.0 4.8e-12 46.0 2.0 2.2 1 1 0 1 1 1 1 Cyclin, C-terminal domain NolV PF06635.12 EMC94503.1 - 0.14 11.5 0.5 0.25 10.7 0.5 1.3 1 0 0 1 1 1 0 Nodulation protein NolV WD40 PF00400.32 EMC94504.1 - 9.5e-13 48.4 13.9 0.92 10.5 0.1 9.9 8 1 1 9 9 9 4 WD domain, G-beta repeat PQQ_2 PF13360.6 EMC94504.1 - 0.00025 20.7 0.7 0.00093 18.8 0.6 2.1 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 EMC94504.1 - 0.036 14.0 0.3 0.74 9.9 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat SUR7 PF06687.12 EMC94505.1 - 3.4e-34 118.3 17.5 4.4e-34 118.0 17.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF5590 PF17881.1 EMC94505.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) DUF2207 PF09972.9 EMC94505.1 - 1.9 7.2 5.3 3.2 6.4 5.4 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Rad4 PF03835.15 EMC94506.1 - 1.5e-14 53.9 0.3 2.8e-14 53.0 0.3 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EMC94506.1 - 2.3e-12 47.4 2.1 5.1e-12 46.2 2.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.32 EMC94507.1 - 9.7e-15 54.7 23.4 0.00015 22.5 0.5 10.3 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC94507.1 - 0.0016 18.7 0.0 3.4 8.0 0.0 4.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMC94508.1 - 4.8e-09 36.7 4.1 0.15 13.0 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Abhydrolase_1 PF00561.20 EMC94509.1 - 4.1e-13 49.6 0.0 1.5e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC94509.1 - 5.5e-11 42.2 0.0 1.3e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMC94509.1 - 1.1e-10 42.5 4.6 2.4e-10 41.4 4.6 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EMC94509.1 - 0.018 15.1 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Nitro_FeMo-Co PF02579.17 EMC94509.1 - 0.079 13.3 0.0 0.87 10.0 0.1 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor FSH1 PF03959.13 EMC94509.1 - 0.093 12.4 0.1 2.2 7.9 0.0 2.5 3 0 0 3 3 3 0 Serine hydrolase (FSH1) MFS_1 PF07690.16 EMC94511.1 - 8.9e-42 143.3 29.6 8.9e-42 143.3 29.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC94511.1 - 8.6e-12 44.7 7.4 8.6e-12 44.7 7.4 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EMC94511.1 - 3.8e-11 42.1 2.9 7.6e-11 41.1 2.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ORC2 PF04084.14 EMC94511.1 - 0.048 12.6 0.2 0.079 11.9 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 DUF3784 PF12650.7 EMC94511.1 - 0.2 11.9 0.1 0.2 11.9 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) FAD_binding_7 PF03441.14 EMC94513.1 - 1.2e-44 152.2 0.6 1.9e-44 151.6 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EMC94513.1 - 1.6e-16 60.7 0.0 3.2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase UQ_con PF00179.26 EMC94515.1 - 0.045 13.4 0.2 0.61 9.7 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-conjugating enzyme Synaptobrevin PF00957.21 EMC94516.1 - 2.7e-28 97.6 3.1 3.1e-28 97.4 3.1 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 EMC94516.1 - 0.0029 17.7 0.1 0.0035 17.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Baculo_F PF12259.8 EMC94516.1 - 0.011 14.3 0.5 0.012 14.2 0.5 1.0 1 0 0 1 1 1 0 Baculovirus F protein EMP24_GP25L PF01105.24 EMC94516.1 - 0.31 10.9 1.9 0.49 10.3 1.9 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Lyase_1 PF00206.20 EMC94517.1 - 4.4e-114 381.1 0.0 6.2e-114 380.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EMC94517.1 - 1.2e-20 73.6 0.0 2.8e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus DUF2508 PF10704.9 EMC94517.1 - 0.11 12.6 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Sel1 PF08238.12 EMC94518.1 - 8.4e-41 137.5 26.1 1.9e-06 28.4 0.0 7.7 7 0 0 7 7 7 6 Sel1 repeat TPR_16 PF13432.6 EMC94518.1 - 0.026 15.1 10.9 0.074 13.7 4.7 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 EMC94518.1 - 0.081 13.3 0.2 0.29 11.5 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn_clus PF00172.18 EMC94520.1 - 3.1e-08 33.6 8.0 4.6e-08 33.1 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF883 PF05957.13 EMC94521.1 - 3.2e-09 37.2 43.3 0.048 14.3 4.3 4.9 1 1 5 6 6 6 6 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 EMC94521.1 - 7.8e-08 32.4 40.0 0.00063 19.7 25.7 2.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EMC94521.1 - 2.2e-06 28.1 49.9 2.6 8.6 5.1 5.7 1 1 1 2 2 1 1 YtxH-like protein ApoLp-III PF07464.11 EMC94521.1 - 0.00034 20.7 35.3 0.018 15.2 18.9 2.7 1 1 2 3 3 3 3 Apolipophorin-III precursor (apoLp-III) DivIVA PF05103.13 EMC94521.1 - 0.00077 19.6 49.1 0.82 9.8 10.3 4.8 1 1 3 4 4 4 4 DivIVA protein ATP-synt_B PF00430.18 EMC94521.1 - 0.037 14.1 56.4 0.81 9.8 9.4 4.7 1 1 4 5 5 5 0 ATP synthase B/B' CF(0) Phasin_2 PF09361.10 EMC94521.1 - 0.13 12.5 54.1 8.4 6.7 19.7 4.6 1 1 3 4 4 4 0 Phasin protein DUF4423 PF14394.6 EMC94521.1 - 0.2 11.4 21.1 0.35 10.5 1.0 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4423) FAM25 PF15825.5 EMC94521.1 - 0.24 11.7 0.2 0.24 11.7 0.2 3.8 2 1 2 4 4 4 0 FAM25 family SepF PF04472.12 EMC94521.1 - 0.31 11.3 6.0 25 5.2 0.1 4.6 1 1 2 4 4 4 0 Cell division protein SepF Mucin-like PF16058.5 EMC94521.1 - 0.37 10.9 54.2 1.9 8.7 7.8 3.1 1 1 2 3 3 3 0 Mucin-like Chlorosome_CsmC PF11098.8 EMC94521.1 - 0.51 10.3 23.9 2 8.4 3.3 4.2 1 1 3 4 4 4 0 Chlorosome envelope protein C DUF5324 PF17258.2 EMC94521.1 - 1.9 8.1 38.2 0.098 12.3 19.2 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5324) PASTA PF03793.19 EMC94521.1 - 2.6 8.0 15.1 35 4.3 0.4 5.4 3 2 1 4 4 4 0 PASTA domain Phasin PF05597.11 EMC94521.1 - 5.2 7.1 30.3 1.1 9.3 1.7 4.2 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fasciclin PF02469.22 EMC94522.1 - 1.4e-51 174.1 0.0 6.5e-27 94.3 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Pro-rich PF15240.6 EMC94522.1 - 0.00055 20.3 0.7 0.00076 19.8 0.7 1.3 1 0 0 1 1 1 1 Proline-rich Sgf11 PF08209.11 EMC94523.1 - 9.3e-12 44.3 2.6 3.4e-11 42.5 0.2 2.3 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-RING_7 PF02591.15 EMC94523.1 - 0.093 12.9 0.1 16 5.8 0.0 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-C2HC_2 PF13913.6 EMC94523.1 - 7.2 6.6 7.6 0.37 10.7 1.6 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type HAD_2 PF13419.6 EMC94525.1 - 2.3e-17 63.6 0.0 4.1e-17 62.8 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMC94525.1 - 3.5e-15 56.9 0.0 1.6e-14 54.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC94525.1 - 1.5e-06 28.1 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EMC94525.1 - 0.0024 18.0 0.0 0.0067 16.5 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 EMC94525.1 - 0.043 12.9 0.1 0.3 10.2 0.0 2.2 3 0 0 3 3 3 0 Trehalose-phosphatase eIF-1a PF01176.19 EMC94528.1 - 8.1e-22 76.8 0.0 1.1e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 EMC94529.1 - 6.5e-27 93.7 0.0 9.8e-27 93.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EMC94529.1 - 2.1e-06 27.4 0.2 4.7e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 WH2 motif Raf1_HTH PF18579.1 EMC94529.1 - 0.033 13.9 0.3 0.063 13.0 0.3 1.4 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain RecX PF02631.16 EMC94529.1 - 0.11 12.9 0.2 3.6 8.1 0.0 2.2 2 0 0 2 2 2 0 RecX family zf-C2H2 PF00096.26 EMC94533.1 - 6.3e-09 35.8 12.5 0.00013 22.2 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC94533.1 - 1.1e-05 25.6 14.5 0.0013 19.1 2.8 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC94533.1 - 6.7e-05 23.4 11.8 0.031 15.1 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Peripla_BP_5 PF13433.6 EMC94533.1 - 0.0033 16.5 0.0 0.0048 15.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain zf-C2H2_jaz PF12171.8 EMC94533.1 - 0.012 15.8 1.6 0.069 13.5 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC94533.1 - 0.013 15.8 3.0 0.034 14.5 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EMC94533.1 - 0.27 11.3 3.5 0.13 12.3 0.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EMC94533.1 - 0.4 10.8 1.9 2.4 8.4 0.8 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 EMC94533.1 - 5.8 6.9 6.2 0.31 11.0 0.5 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Mt_ATP-synt_D PF05873.12 EMC94535.1 - 1.1e-23 83.8 1.2 1.3e-23 83.5 1.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF4047 PF13256.6 EMC94535.1 - 0.041 14.1 1.1 0.063 13.5 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Pedibin PF08182.11 EMC94535.1 - 0.1 12.4 0.9 0.2 11.5 0.3 1.8 2 0 0 2 2 2 0 Pedibin/Hym-346 family DUF2408 PF10303.9 EMC94535.1 - 0.14 12.7 1.6 0.21 12.2 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF2799 PF10973.8 EMC94535.1 - 0.15 12.5 0.3 0.93 10.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2799) TPR_MLP1_2 PF07926.12 EMC94535.1 - 0.35 10.9 4.8 5 7.2 0.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EMC94535.1 - 1.1 9.8 4.1 2.4 8.7 4.2 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region NAC PF01849.18 EMC94536.1 - 3e-23 81.6 0.0 1.9e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 NAC domain PGA2 PF07543.12 EMC94536.1 - 0.65 10.0 12.2 6 6.8 0.3 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 CENP-B_dimeris PF09026.10 EMC94536.1 - 1 9.8 14.7 2 8.8 2.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EMC94536.1 - 1.2 8.8 14.1 3.5 7.3 6.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L14e PF01929.17 EMC94537.1 - 6.3e-24 84.3 0.2 9.7e-24 83.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EMC94537.1 - 0.012 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 KOW motif Glyco_hydro_31 PF01055.26 EMC94538.1 - 1.3e-90 304.8 0.0 1.6e-90 304.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EMC94538.1 - 2.5e-10 40.5 0.2 1.5e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.16 EMC94539.1 - 2.9e-25 88.9 32.4 2.9e-25 88.9 32.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.12 EMC94539.1 - 0.29 11.1 4.6 0.5 10.4 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1304) Abhydrolase_2 PF02230.16 EMC94540.1 - 2.5e-61 207.2 0.0 2.8e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EMC94540.1 - 3.2e-06 26.6 0.1 0.024 13.9 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EMC94540.1 - 4.9e-05 23.3 0.0 0.19 11.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC94540.1 - 0.00026 20.5 0.2 0.053 13.0 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EMC94540.1 - 0.00029 21.5 0.0 0.00068 20.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EMC94540.1 - 0.00065 19.3 0.0 0.0015 18.2 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 EMC94540.1 - 0.016 14.9 0.0 0.097 12.3 0.0 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 EMC94540.1 - 0.046 13.3 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2920 PF11144.8 EMC94540.1 - 0.13 11.4 0.0 9.4 5.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) DUF2974 PF11187.8 EMC94540.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.22 EMC94540.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.25 EMC94540.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 EMC94540.1 - 0.23 11.0 0.0 1.9 7.9 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LigB PF02900.18 EMC94541.1 - 3.9e-40 137.7 0.1 4.9e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MPC PF03650.13 EMC94542.1 - 1.5e-45 153.8 0.1 2.1e-45 153.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers adh_short_C2 PF13561.6 EMC94545.1 - 7.6e-60 202.4 0.3 8.7e-60 202.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC94545.1 - 1.1e-41 142.5 0.1 1.3e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC94545.1 - 8.5e-09 35.6 0.7 1.3e-08 35.0 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMC94545.1 - 0.00099 19.0 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EMC94545.1 - 0.0055 15.9 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 EMC94545.1 - 0.0091 16.7 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.19 EMC94545.1 - 0.012 15.0 0.2 0.029 13.7 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EMC94545.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMC94545.1 - 0.037 13.5 0.0 0.056 12.9 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMC94545.1 - 0.039 13.0 0.0 0.071 12.1 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pecanex_C PF05041.15 EMC94545.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Pecanex protein (C-terminus) ChuX_HutX PF06228.13 EMC94545.1 - 0.15 11.9 0.0 17 5.2 0.0 2.3 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX Gln-synt_C PF00120.24 EMC94546.1 - 3.4e-72 243.3 0.0 4e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain tRNA-synt_1 PF00133.22 EMC94547.1 - 1.1e-145 486.2 0.0 2.2e-145 485.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMC94547.1 - 5.4e-21 75.2 0.2 9.4e-21 74.4 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMC94547.1 - 3.4e-19 68.9 0.0 2e-09 36.7 0.0 4.3 3 1 0 4 4 4 4 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EMC94547.1 - 0.0004 19.9 0.0 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 EMC94547.1 - 0.037 13.9 6.9 0.24 11.3 6.9 2.3 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 EMC94547.1 - 0.06 12.7 0.0 0.61 9.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Cutinase PF01083.22 EMC94548.1 - 8.8e-26 90.9 1.4 8.8e-26 90.9 1.4 2.2 2 1 0 2 2 2 1 Cutinase Mito_carr PF00153.27 EMC94549.1 - 1.1e-69 230.4 0.3 1.3e-24 85.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EMC94549.1 - 2.6e-12 47.0 0.5 1.8e-07 31.5 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EMC94549.1 - 3.1e-11 42.2 2.4 5.1e-06 26.0 0.0 5.3 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.32 EMC94549.1 - 3.2e-11 41.9 1.5 2e-06 26.9 0.0 4.7 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EMC94549.1 - 1.4e-06 27.5 2.0 0.001 18.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EMC94549.1 - 3.8e-05 23.4 0.3 11 5.9 0.0 4.8 4 1 0 4 4 4 2 EF-hand domain pair AAA PF00004.29 EMC94550.1 - 2e-50 170.7 0.0 9.6e-42 142.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMC94550.1 - 3.3e-09 36.4 0.3 1.2e-08 34.6 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EMC94550.1 - 4.6e-07 29.7 0.0 2.5e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EMC94550.1 - 2.3e-06 27.8 0.0 3e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EMC94550.1 - 1.2e-05 25.8 4.0 3.9e-05 24.1 0.0 3.5 3 1 1 4 4 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 EMC94550.1 - 0.00039 20.5 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 EMC94550.1 - 0.0004 20.4 0.0 0.0018 18.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EMC94550.1 - 0.00081 19.6 0.6 0.039 14.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 EMC94550.1 - 0.00086 18.9 0.0 0.0096 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Bromodomain PF00439.25 EMC94550.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.22 EMC94550.1 - 0.0014 19.0 0.0 0.0037 17.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 EMC94550.1 - 0.0043 16.8 0.0 0.02 14.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMC94550.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMC94550.1 - 0.0068 16.7 2.9 0.036 14.3 0.2 3.4 3 1 0 3 3 1 1 AAA domain AAA_18 PF13238.6 EMC94550.1 - 0.02 15.5 1.8 0.077 13.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain TIP49 PF06068.13 EMC94550.1 - 0.023 13.9 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EMC94550.1 - 0.023 14.1 0.1 0.073 12.5 0.1 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EMC94550.1 - 0.024 14.4 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 EMC94550.1 - 0.041 13.8 0.2 0.82 9.5 0.0 2.9 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EMC94550.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 EMC94550.1 - 0.083 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EMC94550.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EMC94550.1 - 0.17 12.2 3.1 0.25 11.6 0.0 2.9 4 0 0 4 4 3 0 AAA domain AAA_3 PF07726.11 EMC94550.1 - 0.17 11.7 1.7 0.41 10.5 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EMC94550.1 - 0.22 12.1 0.0 0.22 12.1 0.0 3.1 3 0 0 3 3 2 0 ABC transporter AAA_11 PF13086.6 EMC94550.1 - 0.3 10.8 0.0 0.3 10.8 0.0 4.3 4 1 0 4 4 3 0 AAA domain NmrA PF05368.13 EMC94551.1 - 8.5e-25 87.7 0.0 1.2e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC94551.1 - 3e-13 50.1 0.0 7.7e-13 48.7 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding TRP PF06011.12 EMC94553.1 - 4.4e-130 434.2 14.2 5.2e-130 434.0 14.2 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EMC94553.1 - 1.2e-35 122.9 0.0 1.9e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 ML-like domain FUN14 PF04930.15 EMC94553.1 - 0.055 13.9 0.0 0.55 10.7 0.0 2.6 2 1 0 2 2 2 0 FUN14 family Aldo_ket_red PF00248.21 EMC94556.1 - 1.2e-49 169.1 0.0 1.4e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MbeD_MobD PF04899.12 EMC94557.1 - 0.1 12.7 1.4 0.34 11.1 0.0 2.7 3 0 0 3 3 3 0 MbeD/MobD like GAS PF13851.6 EMC94557.1 - 1.9 7.8 10.8 0.78 9.1 7.0 2.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding KxDL PF10241.9 EMC94557.1 - 2.7 8.3 7.6 23 5.4 1.2 3.9 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF745 PF05335.13 EMC94557.1 - 2.7 7.7 11.1 7.6 6.2 1.9 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 EMC94557.1 - 4.1 7.5 11.9 12 6.0 6.9 3.5 3 0 0 3 3 3 0 Tropomyosin like GerE PF00196.19 EMC94558.1 - 0.014 14.9 0.1 0.88 9.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 EMC94558.1 - 0.14 12.0 2.2 2.4 8.1 0.1 3.2 3 0 0 3 3 3 0 Homeodomain-like domain FMO-like PF00743.19 EMC94559.1 - 3.5e-15 55.4 0.2 2.3e-13 49.4 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EMC94559.1 - 5.4e-13 48.8 1.0 5e-09 35.8 0.2 3.1 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMC94559.1 - 6.5e-11 42.0 0.0 2.2e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC94559.1 - 7.8e-11 42.1 0.0 2.2e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMC94559.1 - 1.2e-10 41.2 0.0 1.7e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC94559.1 - 8.9e-08 32.3 0.0 2.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMC94559.1 - 6.9e-07 29.4 0.1 0.059 13.4 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EMC94559.1 - 0.0019 17.0 0.3 1.3 7.6 0.0 3.0 4 0 0 4 4 4 2 HI0933-like protein Mqo PF06039.15 EMC94559.1 - 0.0029 16.2 0.0 0.16 10.5 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 EMC94559.1 - 0.0039 16.3 0.0 0.02 13.9 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 EMC94559.1 - 0.0081 15.3 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EMC94559.1 - 0.048 13.0 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Form-deh_trans PF09163.11 EMC94559.1 - 0.11 12.3 5.5 0.41 10.5 4.0 2.6 3 0 0 3 3 3 0 Formate dehydrogenase N, transmembrane FAD_binding_3 PF01494.19 EMC94559.1 - 0.14 11.4 0.1 0.42 9.8 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 EMC94559.1 - 0.16 11.0 0.5 0.87 8.6 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain Pyr_redox PF00070.27 EMC94559.1 - 1.3 9.7 3.7 11 6.6 0.1 3.6 5 0 0 5 5 3 0 Pyridine nucleotide-disulphide oxidoreductase GTP_EFTU PF00009.27 EMC94561.1 - 5.9e-59 198.9 0.0 9.2e-59 198.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EMC94561.1 - 1.3e-33 115.3 0.0 2.5e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EMC94561.1 - 2.5e-32 110.8 0.0 5.1e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EMC94561.1 - 9.3e-23 80.1 0.0 2.3e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMC94561.1 - 8.2e-13 48.6 0.2 5.1e-12 46.0 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EMC94561.1 - 2.1e-05 24.3 0.0 5.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EMC94561.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF442 PF04273.13 EMC94561.1 - 0.037 14.1 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) ATP_bind_1 PF03029.17 EMC94561.1 - 0.11 12.3 0.1 0.35 10.6 0.1 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein WD40 PF00400.32 EMC94562.1 - 2.8e-25 88.1 11.4 3.1e-08 34.1 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC94562.1 - 4.3e-10 39.8 0.0 0.017 15.4 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMC94562.1 - 0.028 13.4 0.1 5.5 5.8 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EMC94562.1 - 0.15 12.0 0.0 0.58 10.0 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Translin PF01997.16 EMC94564.1 - 5.1e-68 229.1 0.0 5.8e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Translin family p450 PF00067.22 EMC94565.1 - 2.6e-57 194.6 0.0 3.5e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sex_peptide PF08138.11 EMC94565.1 - 0.11 12.7 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 Sex peptide (SP) family Adhesin_P1 PF03257.13 EMC94566.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma adhesin P1 Syntaxin PF00804.25 EMC94567.1 - 8e-19 68.1 14.3 8e-19 68.1 14.3 2.1 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.19 EMC94567.1 - 4.8e-17 61.7 0.4 4.8e-17 61.7 0.4 2.2 2 0 0 2 2 2 1 SNARE domain ATP-grasp_2 PF08442.10 EMC94567.1 - 0.012 15.2 0.5 0.021 14.4 0.5 1.4 1 0 0 1 1 1 0 ATP-grasp domain Spectrin PF00435.21 EMC94567.1 - 0.016 15.7 12.8 0.16 12.5 0.0 3.2 2 1 1 3 3 3 0 Spectrin repeat TMPIT PF07851.13 EMC94567.1 - 0.02 14.1 2.5 2.6 7.2 2.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF4094 PF13334.6 EMC94567.1 - 0.04 14.3 1.1 0.04 14.3 1.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) FAM76 PF16046.5 EMC94567.1 - 0.081 12.3 4.4 0.1 11.9 4.4 1.3 1 0 0 1 1 1 0 FAM76 protein YrbL-PhoP_reg PF10707.9 EMC94567.1 - 0.19 11.2 6.1 0.4 10.2 6.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2367 PF10164.9 EMC94567.1 - 0.2 12.2 2.1 0.82 10.2 2.1 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) DUF2207 PF09972.9 EMC94567.1 - 0.32 9.7 1.8 2.2 6.9 1.8 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.8 EMC94567.1 - 2 8.3 9.1 1.4 8.8 0.2 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2721) NPV_P10 PF05531.12 EMC94567.1 - 2 8.9 6.1 10 6.6 3.7 3.0 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIVA PF05103.13 EMC94567.1 - 3.2 7.9 16.9 3.9 7.6 5.8 3.0 1 1 1 2 2 2 0 DivIVA protein DUF745 PF05335.13 EMC94567.1 - 3.5 7.3 15.6 3.5 7.3 13.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) V-SNARE PF05008.15 EMC94567.1 - 3.8 7.9 10.7 0.71 10.3 4.1 2.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DASH_Spc19 PF08287.11 EMC94567.1 - 4.5 7.1 13.3 0.24 11.3 5.6 2.3 2 1 1 3 3 3 0 Spc19 MCU PF04678.13 EMC94567.1 - 5.4 7.1 10.1 0.68 10.0 3.5 2.2 1 1 0 2 2 2 0 Mitochondrial calcium uniporter LMBR1 PF04791.16 EMC94567.1 - 7.2 5.4 10.2 26 3.5 10.2 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein Metallophos PF00149.28 EMC94568.1 - 8.8e-35 121.1 0.1 1.4e-34 120.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EMC94568.1 - 2.3e-17 63.1 0.0 4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_S5 PF00333.20 EMC94569.1 - 4.1e-27 93.9 0.8 9.4e-27 92.8 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EMC94569.1 - 7e-24 83.1 0.0 1.2e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EMC94569.1 - 4.6 7.8 14.7 9.6 6.8 14.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 EVE PF01878.18 EMC94570.1 - 4.4e-39 133.8 0.6 7.7e-39 133.0 0.6 1.4 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.19 EMC94570.1 - 0.1 12.5 0.5 0.1 12.5 0.5 6.2 6 0 0 6 6 6 0 AT hook motif NIBRIN_BRCT_II PF16508.5 EMC94571.1 - 4e-28 98.1 0.2 1.2e-27 96.6 0.0 2.0 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 EMC94571.1 - 2.9e-06 27.5 0.0 8.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain PIP5K PF01504.18 EMC94572.1 - 2.9e-38 131.7 1.3 2.6e-30 105.6 0.2 2.7 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EMC94572.1 - 1.6e-30 106.2 0.0 2.4e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EMC94572.1 - 4.3e-14 52.4 4.8 4.3e-14 52.4 4.8 2.2 2 0 0 2 2 2 1 FYVE zinc finger DZR PF12773.7 EMC94572.1 - 0.076 13.1 7.1 0.17 12.0 1.7 2.9 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 EMC94572.1 - 0.53 10.2 13.0 0.071 13.0 4.7 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YhfH PF14149.6 EMC94572.1 - 3.3 7.8 11.0 0.46 10.5 0.7 3.2 2 1 0 3 3 3 0 YhfH-like protein Zn_Tnp_IS1595 PF12760.7 EMC94572.1 - 3.3 7.8 12.8 6.6 6.8 0.3 3.8 3 0 0 3 3 3 0 Transposase zinc-ribbon domain TPP1 PF10341.9 EMC94573.1 - 4.8e-09 36.2 0.0 1.1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD adh_short PF00106.25 EMC94575.1 - 6.7e-12 45.3 0.0 9.7e-11 41.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC94575.1 - 1.2e-07 31.5 0.0 1.1e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC94575.1 - 0.0016 18.4 0.2 0.0069 16.3 0.0 1.8 2 0 0 2 2 2 1 KR domain Aldedh PF00171.22 EMC94576.1 - 6e-114 381.1 0.0 7.5e-114 380.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AnmK PF03702.14 EMC94576.1 - 0.074 12.1 0.0 8.7 5.3 0.0 2.1 2 0 0 2 2 2 0 Anhydro-N-acetylmuramic acid kinase Redoxin PF08534.10 EMC94577.1 - 1.7e-34 118.6 0.0 2e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMC94577.1 - 2e-09 37.4 0.0 2.5e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family adh_short PF00106.25 EMC94578.1 - 5.4e-22 78.2 0.0 4.8e-21 75.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC94578.1 - 8.9e-12 45.1 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC94578.1 - 7.9e-09 35.7 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC94578.1 - 0.028 13.9 0.0 0.038 13.5 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC94578.1 - 0.039 13.3 0.0 0.06 12.7 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Csm1_B PF18211.1 EMC94578.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Csm1 subunit domain B Rad21_Rec8_N PF04825.13 EMC94579.1 - 1.2e-30 105.9 0.1 2.3e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EMC94579.1 - 7.2e-08 31.6 0.0 1.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein zf-C2H2_assoc PF16606.5 EMC94579.1 - 0.028 14.6 1.4 0.081 13.2 1.4 1.7 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers DUF3984 PF13136.6 EMC94579.1 - 0.88 8.9 4.6 0.64 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) Glyco_hydro_76 PF03663.14 EMC94580.1 - 4.3e-156 520.0 20.7 4.9e-156 519.8 20.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMC94580.1 - 0.45 9.5 10.9 0.083 12.0 0.3 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 HhH-GPD PF00730.25 EMC94581.1 - 3.8e-07 30.5 0.0 8.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EMC94581.1 - 0.034 14.0 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif ICL PF00463.21 EMC94582.1 - 6.2e-197 655.3 0.0 7.1e-197 655.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EMC94582.1 - 5.5e-09 35.8 0.0 9.2e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Citrate_synt PF00285.21 EMC94583.1 - 1.2e-99 333.8 0.0 1.5e-99 333.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Glyco_trans_2_3 PF13632.6 EMC94584.1 - 1.6e-51 175.1 0.6 1.6e-51 175.1 0.6 2.0 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMC94584.1 - 8.5e-06 25.7 0.0 3.8e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EMC94584.1 - 6.4e-05 22.5 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EMC94584.1 - 0.018 15.0 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_hydro_16 PF00722.21 EMC94585.1 - 6.5e-16 58.3 2.3 1.3e-15 57.3 2.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GSH_synth_ATP PF03917.17 EMC94587.1 - 3.2e-105 352.0 0.0 3.7e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EMC94587.1 - 7.1e-26 90.6 0.0 1.3e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase MHB PF16525.5 EMC94587.1 - 0.18 12.1 0.2 4.3 7.6 0.1 3.0 3 0 0 3 3 3 0 Haemophore, haem-binding MmgE_PrpD PF03972.14 EMC94588.1 - 2.6e-144 481.0 0.0 3.3e-144 480.7 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family DUF4844 PF16133.5 EMC94588.1 - 0.16 12.5 0.2 0.43 11.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Ifi-6-16 PF06140.13 EMC94589.1 - 7.3e-05 22.6 15.2 0.00012 22.0 15.2 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family Rpr2 PF04032.16 EMC94590.1 - 7.4e-20 71.0 0.4 1.8e-19 69.8 0.4 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain amfpi-1 PF12190.8 EMC94590.1 - 0.019 15.6 0.8 0.019 15.6 0.8 1.8 2 0 0 2 2 2 0 Fungal protease inhibitor Mut7-C PF01927.16 EMC94590.1 - 0.076 13.1 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain FeS PF04060.13 EMC94590.1 - 0.21 11.3 4.1 10 5.9 0.1 3.3 2 1 0 2 2 2 0 Putative Fe-S cluster DEAD PF00270.29 EMC94591.1 - 9.9e-38 129.6 0.2 1.7e-37 128.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC94591.1 - 5.2e-25 87.9 0.3 2.3e-22 79.4 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EMC94591.1 - 4.7e-09 36.5 0.0 7.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nup35_RRM PF05172.13 EMC94592.1 - 0.0038 17.2 0.0 0.0073 16.3 0.0 1.4 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Septin PF00735.18 EMC94593.1 - 6.5e-07 28.9 0.0 0.025 13.9 0.0 2.3 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 EMC94593.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EMC94593.1 - 0.0086 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EMC94593.1 - 0.024 14.8 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMC94593.1 - 0.048 14.0 0.1 0.26 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EMC94593.1 - 0.13 12.8 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 EMC94593.1 - 0.15 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_primase_lrg PF04104.14 EMC94594.1 - 5.5e-78 262.0 0.0 9.5e-78 261.3 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit A_deaminase PF00962.22 EMC94597.1 - 3.4e-25 89.1 0.3 5.1e-24 85.2 0.3 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase Exo_endo_phos PF03372.23 EMC94598.1 - 7.3e-10 38.7 0.1 1.6e-09 37.7 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AXH PF08517.12 EMC94598.1 - 0.022 15.3 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) Zn_clus PF00172.18 EMC94599.1 - 7.2e-06 26.0 9.3 1.1e-05 25.4 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.13 EMC94601.1 - 5.3e-11 42.9 0.2 1.1e-10 41.9 0.1 1.5 1 1 1 2 2 2 1 Putative cyclase Kelch_4 PF13418.6 EMC94602.1 - 5.3e-16 58.4 0.9 9.4e-07 28.7 0.0 4.9 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EMC94602.1 - 7.6e-14 51.0 0.1 0.0002 20.8 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EMC94602.1 - 1.6e-13 50.6 6.0 3.8e-08 33.4 0.0 5.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EMC94602.1 - 8.5e-13 48.0 1.2 8.8e-05 22.4 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 EMC94602.1 - 1.1e-09 38.2 0.2 0.0035 17.6 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EMC94602.1 - 1.5e-09 37.4 0.2 0.001 19.0 0.0 3.8 3 0 0 3 3 3 2 Kelch motif BTB PF00651.31 EMC94602.1 - 0.0069 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RAG2 PF03089.14 EMC94602.1 - 0.23 10.4 0.0 0.45 9.4 0.0 1.4 1 0 0 1 1 1 0 Recombination activating protein 2 AhpC-TSA PF00578.21 EMC94603.1 - 2.7e-30 104.8 0.0 3.6e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMC94603.1 - 2.6e-13 49.9 0.0 3.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EMC94603.1 - 1.1e-10 41.1 0.1 2.2e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin WH2 PF02205.20 EMC94605.1 - 0.0048 16.7 0.8 0.15 11.9 0.2 2.4 2 0 0 2 2 2 2 WH2 motif Histone PF00125.24 EMC94606.1 - 1.2e-14 54.8 0.1 1.4e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EMC94606.1 - 0.00021 21.4 0.0 0.00026 21.1 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EMC94606.1 - 0.0063 16.9 0.1 0.0075 16.6 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EMC94606.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EMC94606.1 - 0.074 13.1 0.1 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated NTF2 PF02136.20 EMC94607.1 - 3.7e-25 88.8 1.4 6.6e-25 88.0 1.4 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EMC94607.1 - 8.3e-09 35.1 0.1 1.7e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMC94607.1 - 0.035 14.1 0.1 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Asparaginase PF00710.20 EMC94607.1 - 1.9 8.0 3.5 1.1 8.8 0.3 2.1 3 0 0 3 3 3 0 Asparaginase, N-terminal PCI PF01399.27 EMC94608.1 - 1.7e-10 41.3 0.7 6.6e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 PCI domain ZYG-11_interact PF05884.12 EMC94608.1 - 6 6.2 5.7 1.6 8.1 2.1 1.8 2 0 0 2 2 2 0 Interactor of ZYG-11 G-gamma PF00631.22 EMC94609.1 - 4.2e-21 74.7 0.0 4.9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain HLH PF00010.26 EMC94610.1 - 1.2e-10 41.2 0.0 3e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PDZ_3 PF17815.1 EMC94610.1 - 0.24 11.2 1.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 PDZ domain FAM153 PF15722.5 EMC94610.1 - 0.26 11.6 2.5 0.74 10.2 0.2 2.5 2 0 0 2 2 2 0 FAM153 family Esterase PF00756.20 EMC94611.1 - 8.6e-54 182.8 0.0 1.1e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EMC94611.1 - 0.0001 21.9 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EMC94611.1 - 0.00013 21.3 0.0 0.00034 19.9 0.0 1.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EMC94611.1 - 0.00079 18.4 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 EMC94611.1 - 0.0011 18.5 0.5 0.0074 15.9 0.5 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 EMC94611.1 - 0.0012 18.4 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 EMC94611.1 - 0.014 16.0 0.1 0.02 15.5 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EMC94611.1 - 0.022 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 EMC94611.1 - 0.056 12.1 0.0 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.11 EMC94611.1 - 0.094 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase LCAT PF02450.15 EMC94611.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Mpv17_PMP22 PF04117.12 EMC94612.1 - 6.8e-18 64.7 0.3 6.8e-18 64.7 0.3 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family HHH_3 PF12836.7 EMC94612.1 - 0.14 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Rdx PF10262.9 EMC94613.1 - 3e-33 113.8 0.0 3.5e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Rdx family Methyltransf_11 PF08241.12 EMC94615.1 - 0.0022 18.6 0.0 0.0048 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC94615.1 - 0.087 13.5 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NTP_transferase PF00483.23 EMC94615.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Peptidase_M22 PF00814.25 EMC94616.1 - 4.9e-48 164.2 0.0 1.5e-45 156.0 0.0 2.9 1 1 0 1 1 1 1 Glycoprotease family DUF1932 PF09130.11 EMC94617.1 - 9.5e-27 92.8 0.2 2.3e-26 91.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 EMC94617.1 - 4.8e-06 27.1 0.0 4.9e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EMC94617.1 - 5.8e-06 26.6 0.0 1.5e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EMC94617.1 - 0.0016 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HTH_39 PF14090.6 EMC94617.1 - 0.025 14.3 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Rossmann-like PF10727.9 EMC94617.1 - 0.039 13.8 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain Phytase-like PF13449.6 EMC94618.1 - 6.4e-38 131.3 0.0 9.4e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase DUF2838 PF10998.8 EMC94619.1 - 1.3e-42 144.5 11.4 1.3e-42 144.5 11.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Pox_F11 PF04943.12 EMC94619.1 - 0.018 14.1 0.1 0.026 13.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein Val_tRNA-synt_C PF10458.9 EMC94619.1 - 0.19 12.0 4.0 1.5 9.2 0.2 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Exonuc_VII_L PF02601.15 EMC94619.1 - 0.38 10.3 1.9 0.58 9.7 1.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GDI PF00996.18 EMC94620.1 - 2.5e-29 102.1 0.0 7.9e-28 97.1 0.0 2.0 1 1 0 1 1 1 1 GDP dissociation inhibitor Wbp11 PF09429.10 EMC94623.1 - 4e-21 75.2 13.8 4e-21 75.2 13.8 2.3 3 0 0 3 3 3 1 WW domain binding protein 11 Borrelia_P83 PF05262.11 EMC94623.1 - 2 6.8 8.5 2.1 6.7 8.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PIP5K PF01504.18 EMC94624.1 - 3.6e-43 147.8 0.0 9.2e-42 143.2 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MFS_1 PF07690.16 EMC94625.1 - 1.3e-39 136.2 32.7 5.5e-33 114.3 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC94625.1 - 6e-10 38.6 1.2 8.5e-09 34.8 0.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EMC94625.1 - 0.00017 20.6 4.7 0.00017 20.6 4.7 3.0 2 2 1 3 3 3 1 MFS_1 like family MFS_4 PF06779.14 EMC94625.1 - 0.00083 18.7 0.9 0.00083 18.7 0.9 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2530 PF10745.9 EMC94625.1 - 0.086 13.1 5.1 0.25 11.6 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) GFO_IDH_MocA PF01408.22 EMC94626.1 - 5.2e-19 69.2 0.1 9.2e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EMC94626.1 - 0.081 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ECH_1 PF00378.20 EMC94627.1 - 6.5e-23 81.3 0.0 7.7e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMC94627.1 - 6.9e-10 38.9 0.0 8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACOX PF01756.19 EMC94628.1 - 1.1e-41 142.3 0.4 1.1e-41 142.3 0.4 2.1 3 0 0 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EMC94628.1 - 5e-22 78.8 0.6 1.2e-21 77.6 0.6 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EMC94628.1 - 3.5e-09 36.7 0.0 1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EMC94628.1 - 0.00014 22.1 3.0 0.0014 18.9 2.1 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMC94628.1 - 0.036 14.7 0.0 0.095 13.4 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain AMP-binding PF00501.28 EMC94629.1 - 8.3e-58 196.0 0.0 1.2e-57 195.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC94629.1 - 1.1e-12 48.7 0.0 2.6e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LpxD PF04613.14 EMC94629.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD SAP PF02037.27 EMC94630.1 - 1.3e-09 37.6 0.5 3.4e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 EMC94630.1 - 8.6e-07 28.7 0.1 8.6e-07 28.7 0.1 2.2 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain DUF630 PF04783.12 EMC94630.1 - 0.13 12.4 0.1 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Nnf1 PF03980.14 EMC94631.1 - 4.6e-23 81.7 0.0 6.8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Nnf1 SGL PF08450.12 EMC94632.1 - 1.3e-58 198.5 0.1 1.7e-58 198.1 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region bZIP_2 PF07716.15 EMC94637.1 - 0.0036 17.4 13.6 0.0068 16.5 13.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMC94637.1 - 0.049 14.2 8.5 0.094 13.2 8.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Mur_ligase_M PF08245.12 EMC94638.1 - 0.00096 19.2 0.0 1.1 9.2 0.0 3.0 2 1 1 3 3 3 2 Mur ligase middle domain MutS_V PF00488.21 EMC94639.1 - 3.4e-68 229.4 0.1 5.6e-68 228.7 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMC94639.1 - 1.2e-39 136.6 0.0 2.1e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EMC94639.1 - 5.5e-34 116.8 0.1 5.5e-33 113.6 0.0 2.5 3 0 0 3 3 3 1 MutS domain I MutS_IV PF05190.18 EMC94639.1 - 4.6e-16 58.9 0.2 9.4e-16 57.9 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EMC94639.1 - 8.5e-12 45.5 0.0 2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 EMC94639.1 - 0.019 15.5 2.0 0.061 13.8 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EMC94639.1 - 0.032 14.0 0.1 0.084 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EMC94639.1 - 0.072 12.9 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MqsA_antitoxin PF15731.5 EMC94639.1 - 0.15 12.1 0.0 0.9 9.6 0.0 2.1 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA AAA_27 PF13514.6 EMC94639.1 - 0.16 11.6 0.0 0.41 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Dimer_Tnp_Tn5 PF02281.16 EMC94640.1 - 0.16 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain adh_short PF00106.25 EMC94642.1 - 3e-15 56.2 0.0 5.6e-15 55.3 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC94642.1 - 7.5e-11 42.0 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EMC94642.1 - 1.3e-06 28.4 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC94642.1 - 4.2e-06 26.4 0.0 5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMC94642.1 - 0.00028 20.9 0.1 0.00068 19.6 0.1 1.6 2 0 0 2 2 2 1 KR domain DUF1771 PF08590.10 EMC94642.1 - 0.56 10.6 4.2 0.33 11.3 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Glyco_hydro_65C PF03633.15 EMC94647.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain DUF2914 PF11141.8 EMC94653.1 - 0.12 12.2 1.5 0.32 10.8 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) Cytochrom_B561 PF03188.16 EMC94654.1 - 2.7e-06 27.5 4.8 5.8e-06 26.5 4.8 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EMC94654.1 - 1.5 8.9 11.2 0.18 11.9 1.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Aldedh PF00171.22 EMC94655.1 - 2e-176 587.1 0.2 2.3e-176 586.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MMS19_N PF14500.6 EMC94655.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Amidase PF01425.21 EMC94658.1 - 2.2e-79 267.5 0.0 1e-77 262.0 0.0 2.0 1 1 0 1 1 1 1 Amidase Glucosaminidase PF01832.20 EMC94658.1 - 0.022 15.2 0.0 0.2 12.2 0.0 2.6 2 1 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase DUF5315 PF17242.2 EMC94659.1 - 3.2e-20 71.7 1.1 3.2e-20 71.7 1.1 1.6 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Scytalone_dh PF02982.14 EMC94659.1 - 0.14 11.9 0.1 0.61 9.9 0.0 1.9 1 1 1 2 2 2 0 Scytalone dehydratase CS PF04969.16 EMC94660.1 - 2.4e-16 60.5 0.1 5.1e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 CS domain Bactofilin PF04519.13 EMC94660.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Polymer-forming cytoskeletal ATP-synt_DE_N PF02823.16 EMC94661.1 - 1.4e-17 63.3 0.0 2.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain GH114_assoc PF14741.6 EMC94662.1 - 0.11 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain TolA_bind_tri PF16331.5 EMC94663.1 - 0.0027 17.8 4.6 0.0027 17.8 4.6 10.1 8 3 2 11 11 11 2 TolA binding protein trimerisation DivIC PF04977.15 EMC94663.1 - 0.0092 15.7 2.5 0.0092 15.7 2.5 12.2 7 5 6 14 14 14 3 Septum formation initiator CLZ PF16526.5 EMC94663.1 - 0.017 15.5 4.9 0.017 15.5 4.9 9.6 5 1 4 9 9 9 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 EMC94663.1 - 0.74 9.9 57.5 0.015 15.3 5.6 7.6 3 1 3 7 7 7 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EMC94663.1 - 0.85 10.1 52.6 3.3 8.2 0.7 9.8 4 4 6 10 10 10 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 EMC94663.1 - 2.5 8.2 119.5 0.016 15.3 9.7 7.8 4 1 4 8 8 8 0 Uncharacterised protein family (UPF0242) N-terminus Alpha-L-AF_C PF06964.12 EMC94664.1 - 5.3e-20 72.2 0.0 1.4e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Fungal_trans_2 PF11951.8 EMC94665.1 - 1.4e-11 43.8 0.3 2e-11 43.3 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC94665.1 - 1.1e-07 31.9 9.6 2.4e-07 30.8 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_C PF02782.16 EMC94668.1 - 2e-26 93.0 0.0 3.1e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EMC94668.1 - 9.9e-15 54.8 0.0 7.2e-10 38.8 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain adh_short PF00106.25 EMC94670.1 - 1.7e-21 76.6 1.3 3.1e-21 75.7 1.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC94670.1 - 7.1e-13 48.7 2.8 1.7e-12 47.4 2.8 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMC94670.1 - 4.8e-06 26.2 0.5 4.2e-05 23.1 0.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMC94670.1 - 2.3e-05 24.4 1.5 0.003 17.5 1.5 2.8 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EMC94670.1 - 0.00024 20.3 0.0 0.0003 20.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein FtsJ PF01728.19 EMC94670.1 - 0.0014 18.7 0.1 0.0019 18.4 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Polysacc_synt_2 PF02719.15 EMC94670.1 - 0.096 11.8 0.1 0.24 10.5 0.1 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Cupin_2 PF07883.11 EMC94671.1 - 5.4e-13 48.4 0.3 6.9e-13 48.1 0.3 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EMC94671.1 - 2.9e-07 30.2 0.0 3.3e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EMC94671.1 - 0.0037 16.9 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) DUF4437 PF14499.6 EMC94671.1 - 0.028 13.5 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) AraC_binding PF02311.19 EMC94671.1 - 0.055 13.4 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain Peptidase_C14 PF00656.22 EMC94671.1 - 0.067 13.1 0.0 0.07 13.1 0.0 1.1 1 0 0 1 1 1 0 Caspase domain HutD PF05962.11 EMC94671.1 - 0.097 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 HutD Cupin_6 PF12852.7 EMC94671.1 - 0.13 12.0 0.0 0.15 11.7 0.0 1.2 1 1 0 1 1 1 0 Cupin CENP-C_C PF11699.8 EMC94671.1 - 0.21 11.8 0.0 0.28 11.4 0.0 1.1 1 0 0 1 1 1 0 Mif2/CENP-C like AMP-binding PF00501.28 EMC94672.1 - 4.6e-59 200.1 0.0 5.6e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC94672.1 - 1.8e-10 41.7 0.0 4.7e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNase_PH PF01138.21 EMC94673.1 - 4.1e-19 69.4 0.0 7.5e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 SnoaL PF07366.12 EMC94675.1 - 0.081 12.7 0.1 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Cyclin PF08613.11 EMC94676.1 - 2.3e-05 24.8 0.0 3.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EMC94676.1 - 0.0078 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain LINES_N PF14694.6 EMC94677.1 - 0.12 11.9 0.2 0.14 11.6 0.2 1.4 1 1 0 1 1 1 0 Lines N-terminus ECH_1 PF00378.20 EMC94678.1 - 2.9e-37 128.3 0.0 3.1e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMC94678.1 - 2.6e-23 83.1 0.0 2.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF287 PF03384.14 EMC94678.1 - 0.12 12.7 0.6 0.25 11.8 0.6 1.4 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 ADH_N PF08240.12 EMC94679.1 - 7.2e-27 93.4 0.4 1.3e-26 92.6 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC94679.1 - 8.6e-07 29.0 0.4 1.6e-06 28.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMC94679.1 - 0.00053 19.5 0.0 0.0039 16.7 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 EMC94679.1 - 0.00064 19.6 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.14 EMC94679.1 - 0.0013 17.6 0.3 0.0048 15.6 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EMC94679.1 - 0.089 12.1 0.6 0.16 11.2 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EMC94679.1 - 0.19 11.0 0.2 0.27 10.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pro_isomerase PF00160.21 EMC94680.1 - 1.2e-55 188.1 0.0 1.4e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 EMC94680.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) Pkinase PF00069.25 EMC94682.1 - 1.3e-59 201.7 0.0 1.9e-58 197.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC94682.1 - 1.6e-27 96.5 0.1 3.9e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EMC94682.1 - 0.00091 19.9 0.2 0.0037 17.9 0.2 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EMC94682.1 - 0.0073 15.7 0.1 0.031 13.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EMC94682.1 - 0.012 15.6 5.3 0.23 11.4 0.1 3.7 3 1 1 4 4 4 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMC94682.1 - 0.083 11.8 0.0 0.15 11.0 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain GATA PF00320.27 EMC94683.1 - 4.2e-16 58.3 2.5 8.5e-16 57.3 2.5 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EMC94683.1 - 1e-12 47.6 1.1 1.9e-12 46.7 1.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.11 EMC94683.1 - 0.022 15.4 2.8 0.022 15.4 2.8 3.8 3 1 1 4 4 4 0 Nitrogen regulatory protein AreA N terminus NINJA_B PF16136.5 EMC94685.1 - 0.013 15.8 0.6 0.018 15.4 0.6 1.1 1 0 0 1 1 1 0 Putative nuclear localisation signal DLH PF01738.18 EMC94687.1 - 7.1e-20 71.5 0.0 8.3e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Pkinase PF00069.25 EMC94688.1 - 1.5e-52 178.5 0.0 2.8e-34 118.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMC94688.1 - 1e-33 116.8 0.0 5.4e-33 114.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Cep57_CLD_2 PF14197.6 EMC94688.1 - 1.2e-06 28.5 2.6 1.2e-06 28.5 2.6 2.1 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 Kinase-like PF14531.6 EMC94688.1 - 1.5e-05 24.5 0.1 3.5e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EMC94688.1 - 0.0059 16.6 1.5 0.049 13.5 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family APG6_N PF17675.1 EMC94688.1 - 6 7.4 14.8 15 6.2 14.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region BTB PF00651.31 EMC94689.1 - 5.9e-21 74.8 0.0 1.6e-10 41.2 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 EMC94689.1 - 7.6e-07 29.6 0.0 2.3e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMC94689.1 - 1.4e-06 28.5 0.0 4.2e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMC94689.1 - 3.4e-06 27.5 0.0 7.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EMC94689.1 - 0.0004 20.7 0.0 0.012 16.0 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EMC94689.1 - 0.004 17.5 0.1 0.12 13.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat AATase PF07247.12 EMC94690.1 - 4.7e-17 61.7 0.0 1.4e-15 56.8 0.0 2.6 2 1 0 2 2 2 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 EMC94690.1 - 0.068 12.9 2.1 0.091 12.5 0.3 2.0 2 1 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Ctr PF04145.15 EMC94691.1 - 1.1e-34 120.2 0.1 1.3e-34 120.0 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF2798 PF11391.8 EMC94691.1 - 3 7.9 7.3 0.44 10.6 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) Ferritin_2 PF13668.6 EMC94692.1 - 3.1e-24 85.7 7.2 5.5e-22 78.4 7.2 2.3 1 1 0 1 1 1 1 Ferritin-like domain ChpA-C PF03777.13 EMC94692.1 - 0.086 12.7 1.0 0.28 11.1 1.0 1.9 1 0 0 1 1 1 0 ChpA-C RGS PF00615.19 EMC94694.1 - 2.4e-07 31.0 0.0 3.2e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF5396 PF17374.2 EMC94694.1 - 0.11 10.3 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5396) DUF2892 PF11127.8 EMC94694.1 - 0.17 11.9 1.9 0.54 10.3 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Acetyltransf_1 PF00583.25 EMC94695.1 - 5.1e-10 39.6 0.2 6.7e-10 39.2 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC94695.1 - 9.1e-09 35.6 0.7 1.3e-08 35.1 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC94695.1 - 1e-08 35.2 0.1 1.4e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AdoMet_MTase PF07757.13 EMC94696.1 - 7.2e-41 139.0 0.0 1.2e-39 135.1 0.0 2.2 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EMC94696.1 - 0.012 15.6 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Pkinase PF00069.25 EMC94698.1 - 7.3e-64 215.7 0.1 2.1e-62 210.9 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Fungal_KA1 PF16797.5 EMC94698.1 - 4.2e-38 129.7 0.1 8.3e-38 128.7 0.1 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 EMC94698.1 - 4.3e-31 108.1 0.0 1.4e-30 106.5 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 EMC94698.1 - 7.3e-05 22.4 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EMC94698.1 - 7.5e-05 22.8 0.1 0.0009 19.2 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EMC94698.1 - 0.00017 21.0 0.0 0.00045 19.6 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMC94698.1 - 0.0044 16.0 0.0 0.0044 16.0 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain DUF1679 PF07914.11 EMC94698.1 - 0.46 9.3 1.3 6.8 5.4 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1679) Fe_hyd_lg_C PF02906.14 EMC94699.1 - 0.17 11.5 0.2 0.23 11.1 0.2 1.1 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Form_Nir_trans PF01226.17 EMC94700.1 - 9.2e-72 241.2 23.0 1.1e-71 241.0 23.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Polysacc_synt_4 PF04669.13 EMC94701.1 - 5.3e-22 78.3 1.3 2.2e-20 73.0 1.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Microtub_bind PF13931.6 EMC94701.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding ABC_membrane PF00664.23 EMC94702.1 - 6.3e-90 301.5 24.2 2.4e-46 158.6 8.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMC94702.1 - 1.3e-56 190.9 0.0 2.1e-28 99.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMC94702.1 - 1.1e-14 54.5 3.0 8.3e-06 25.4 0.7 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMC94702.1 - 5.1e-09 35.8 0.4 0.0036 17.0 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EMC94702.1 - 6.7e-09 36.1 0.3 0.00021 21.6 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EMC94702.1 - 5e-08 33.1 0.1 0.16 11.8 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EMC94702.1 - 1.4e-06 28.1 0.2 0.15 11.7 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EMC94702.1 - 2.3e-06 28.1 0.3 0.043 14.2 0.1 3.8 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMC94702.1 - 5e-06 26.5 0.0 0.14 12.1 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase NACHT PF05729.12 EMC94702.1 - 4.7e-05 23.4 0.1 0.02 14.8 0.0 3.4 2 1 0 2 2 2 1 NACHT domain ABC_ATPase PF09818.9 EMC94702.1 - 0.00015 20.7 10.0 0.0008 18.3 0.2 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 EMC94702.1 - 0.00027 20.8 0.1 0.28 10.8 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 EMC94702.1 - 0.00089 19.4 0.0 0.8 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EMC94702.1 - 0.0011 19.6 0.9 0.35 11.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMC94702.1 - 0.0025 17.6 0.7 0.71 9.6 0.2 3.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMC94702.1 - 0.0034 17.5 0.0 3.2 7.9 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 EMC94702.1 - 0.0037 17.3 0.6 3.6 7.6 0.1 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EMC94702.1 - 0.0043 16.8 0.0 1.1 9.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 EMC94702.1 - 0.006 17.1 0.0 2.4 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 EMC94702.1 - 0.012 14.6 0.0 2.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PRK PF00485.18 EMC94702.1 - 0.016 15.0 0.1 1.4 8.6 0.1 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EMC94702.1 - 0.025 15.0 0.0 8.7 6.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 EMC94702.1 - 0.027 14.4 0.1 7.3 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 APS_kinase PF01583.20 EMC94702.1 - 0.029 14.3 1.3 3.3 7.6 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase ATP-synt_ab PF00006.25 EMC94702.1 - 0.032 13.9 0.1 37 3.9 0.0 3.4 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 EMC94702.1 - 0.045 13.3 0.1 14 5.1 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EMC94702.1 - 0.068 13.4 2.3 7.5 6.9 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EMC94702.1 - 0.086 12.6 0.5 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EMC94702.1 - 0.12 12.4 4.7 0.3 11.2 0.1 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_13 PF13166.6 EMC94702.1 - 0.16 10.6 0.3 7.3 5.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EMC94702.1 - 0.16 11.3 0.4 17 4.7 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family CbiA PF01656.23 EMC94702.1 - 0.17 11.9 0.8 26 4.9 0.2 3.2 4 0 0 4 4 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 EMC94702.1 - 0.18 10.9 1.4 14 4.8 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain ATPase PF06745.13 EMC94702.1 - 1.2 8.4 4.3 20 4.4 0.1 3.2 3 0 0 3 3 3 0 KaiC DUF3291 PF11695.8 EMC94703.1 - 0.08 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) F-box-like PF12937.7 EMC94704.1 - 0.003 17.4 0.0 0.012 15.5 0.0 2.1 1 1 0 1 1 1 1 F-box-like Antigen_Bd37 PF11641.8 EMC94704.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein adh_short_C2 PF13561.6 EMC94705.1 - 6.7e-56 189.5 0.1 8e-56 189.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC94705.1 - 8.1e-49 165.7 0.3 1.1e-48 165.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC94705.1 - 1.2e-14 54.7 0.1 1.6e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC94705.1 - 0.0002 20.9 0.1 0.00032 20.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC94705.1 - 0.0073 15.7 0.0 0.098 12.0 0.0 2.3 2 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase NusB PF01029.18 EMC94705.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 NusB family Sugar_tr PF00083.24 EMC94708.1 - 3.4e-114 382.2 27.1 6e-114 381.4 27.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC94708.1 - 1.8e-20 73.2 51.0 5.8e-16 58.4 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EMC94711.1 - 1.3e-29 103.2 23.2 1.3e-29 103.2 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMC94711.1 - 0.00011 20.7 3.8 0.00018 20.1 3.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acetyltransf_10 PF13673.7 EMC94712.1 - 9.2e-12 45.0 0.2 3.4e-11 43.2 0.1 2.0 1 1 2 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC94712.1 - 2.2e-08 34.3 0.1 6.5e-08 32.8 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC94712.1 - 6.5e-08 32.9 0.1 2e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC94712.1 - 0.021 14.9 0.1 0.095 12.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC94712.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Lactamase_B PF00753.27 EMC94713.1 - 2.6e-19 70.0 4.9 3.6e-19 69.6 4.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMC94713.1 - 0.0014 18.2 0.4 0.0022 17.6 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CTP_transf_like PF01467.26 EMC94714.1 - 0.00025 21.3 0.0 0.00075 19.7 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like DHR10 PF18595.1 EMC94715.1 - 0.0098 15.9 17.8 0.028 14.5 3.2 2.7 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain Ead_Ea22 PF13935.6 EMC94715.1 - 0.018 15.7 4.0 0.018 15.7 4.0 2.2 3 0 0 3 3 3 0 Ead/Ea22-like protein Prominin PF05478.11 EMC94715.1 - 0.6 8.0 1.8 0.86 7.5 1.8 1.2 1 0 0 1 1 1 0 Prominin DUF1043 PF06295.12 EMC94715.1 - 0.7 9.9 5.4 0.51 10.3 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Seryl_tRNA_N PF02403.22 EMC94715.1 - 4.5 7.5 13.1 0.43 10.8 2.2 3.3 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF5320 PF17253.2 EMC94715.1 - 4.9 8.3 7.3 2.5 9.2 1.6 3.2 3 2 1 4 4 4 0 Family of unknown function (DUF5320) Ribophorin_II PF05817.14 EMC94716.1 - 2.7e-29 102.2 0.0 3.2e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II MLD PF11647.8 EMC94717.1 - 0.12 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 Membrane Localization Domain HcyBio PF01837.16 EMC94719.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation Peptidase_M28 PF04389.17 EMC94721.1 - 1.1e-33 116.6 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Spc7 PF08317.11 EMC94722.1 - 3.1e-100 335.1 14.2 5.3e-100 334.3 14.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.6 EMC94722.1 - 8.9e-76 255.9 73.1 3.9e-61 207.5 25.1 5.4 1 1 4 5 5 5 3 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.6 EMC94722.1 - 3.8e-18 65.3 0.0 7.3e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 Ribosomal_S17_N PF16205.5 EMC94723.1 - 1.9e-33 114.6 0.7 3.4e-33 113.8 0.7 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EMC94723.1 - 5e-27 93.8 0.4 9.2e-27 92.9 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4521 PF15021.6 EMC94724.1 - 0.0013 18.6 0.1 0.0016 18.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4521) Fib_alpha PF08702.10 EMC94724.1 - 0.015 15.5 1.7 0.018 15.2 1.7 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family T3SchapCesA PF11439.8 EMC94724.1 - 0.037 14.2 0.4 0.042 14.0 0.4 1.1 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Lant_dehydr_C PF14028.6 EMC94724.1 - 0.044 13.3 1.1 0.083 12.4 1.1 1.3 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term ArgoMid PF16487.5 EMC94724.1 - 0.12 12.6 0.1 0.3 11.4 0.0 1.6 1 1 1 2 2 2 0 Mid domain of argonaute FUSC PF04632.12 EMC94724.1 - 0.6 8.6 3.2 0.57 8.6 3.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family KfrA_N PF11740.8 EMC94724.1 - 9.4 7.0 12.9 8.6 7.1 4.0 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Cyt-b5 PF00173.28 EMC94725.1 - 3e-14 52.9 0.0 4.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SET PF00856.28 EMC94728.1 - 1.1e-15 58.4 0.0 4.7e-15 56.4 0.0 1.9 1 1 0 1 1 1 1 SET domain preSET_CXC PF18264.1 EMC94728.1 - 3e-07 30.8 11.6 3e-07 30.8 11.6 2.6 2 1 1 3 3 3 1 CXC domain Baculo_LEF-11 PF06385.12 EMC94728.1 - 0.02 15.3 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein DUF1071 PF06378.11 EMC94728.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1071) But2 PF09792.9 EMC94729.1 - 3e-43 147.6 0.2 5.8e-43 146.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain MRP-S26 PF14943.6 EMC94730.1 - 0.044 13.7 4.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 NGP1NT PF08153.12 EMC94731.1 - 3.6e-47 159.8 0.1 6.5e-47 158.9 0.1 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EMC94731.1 - 6.4e-17 61.7 0.2 1.9e-13 50.5 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EMC94731.1 - 0.00034 20.2 0.1 0.0007 19.2 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMC94731.1 - 0.002 18.1 0.0 0.0057 16.6 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EMC94731.1 - 0.0021 18.2 0.0 1.1 9.3 0.0 3.4 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 EMC94731.1 - 0.003 17.0 0.1 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMC94731.1 - 0.073 12.6 0.0 5.6 6.5 0.0 3.0 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain UvrD-helicase PF00580.21 EMC94732.1 - 1.8e-59 201.8 6.4 2e-58 198.4 2.7 2.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EMC94732.1 - 8.6e-59 199.7 0.0 2.7e-57 194.7 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EMC94732.1 - 6.7e-30 104.4 0.0 1.7e-29 103.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EMC94732.1 - 1.2e-12 47.4 0.0 3.5e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EMC94732.1 - 3e-07 30.4 0.5 0.0014 18.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EMC94732.1 - 0.0016 18.3 1.7 0.0025 17.6 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMC94732.1 - 0.0052 17.1 0.3 1.4 9.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EMC94732.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Prenyltransf PF01255.19 EMC94732.1 - 0.16 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase CDC27 PF09507.10 EMC94732.1 - 0.62 9.4 10.2 0.11 11.9 0.5 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 FKBP_C PF00254.28 EMC94733.1 - 2.7e-33 114.1 0.0 3.4e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AMP-binding PF00501.28 EMC94734.1 - 2.3e-67 227.5 0.1 3.5e-35 121.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EMC94734.1 - 3.4e-12 47.2 0.3 6.2e-12 46.3 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF570 PF04489.13 EMC94735.1 - 0.058 12.0 0.0 0.058 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF570) DnaJ-X PF14308.6 EMC94736.1 - 7.7e-73 244.4 1.9 7.7e-73 244.4 1.9 2.5 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.31 EMC94736.1 - 7e-26 90.1 1.3 1.4e-25 89.2 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain Ndc1_Nup PF09531.10 EMC94736.1 - 0.5 9.0 5.5 0.83 8.3 5.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DHDPS PF00701.22 EMC94737.1 - 3.1e-36 124.6 0.0 3.6e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 EMC94738.1 - 5.5e-22 78.2 51.7 5.5e-22 78.2 51.7 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMC94738.1 - 9.7e-20 70.5 24.3 1.3e-19 70.0 24.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 EMC94739.1 - 5e-21 75.1 0.2 2.4e-18 66.3 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC94739.1 - 1.7e-11 44.1 0.0 2.4e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC94739.1 - 3.6e-09 36.8 0.1 5.6e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC94739.1 - 0.00045 19.8 0.0 0.00059 19.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family BolA PF01722.18 EMC94740.1 - 2.1e-29 101.6 1.2 2.6e-29 101.3 1.2 1.1 1 0 0 1 1 1 1 BolA-like protein NTP_transf_6 PF06042.11 EMC94740.1 - 0.073 12.9 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase CDC45 PF02724.14 EMC94741.1 - 0.0077 14.6 2.0 0.0098 14.2 2.0 1.1 1 0 0 1 1 1 1 CDC45-like protein PRP9_N PF16958.5 EMC94741.1 - 0.02 14.9 0.5 0.02 14.9 0.5 1.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus Saw1 PF11561.8 EMC94741.1 - 0.024 14.2 0.1 0.19 11.2 0.1 2.2 2 0 0 2 2 2 0 Single strand annealing-weakened 1 Zip PF02535.22 EMC94742.1 - 2.9e-67 227.3 0.2 3.3e-67 227.1 0.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DAO PF01266.24 EMC94743.1 - 7.9e-35 121.1 0.1 9.9e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC94743.1 - 8.5e-06 25.9 0.0 2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 EMC94743.1 - 0.00025 20.5 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.14 EMC94743.1 - 0.00035 19.9 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC94743.1 - 0.00059 19.0 0.5 0.0021 17.2 0.5 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 EMC94743.1 - 0.0042 17.1 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EMC94743.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EMC94743.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EMC94743.1 - 0.065 13.2 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EMC94743.1 - 0.068 12.2 0.0 9.1 5.2 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EMC94743.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglD_N PF17836.1 EMC94743.1 - 0.17 12.5 0.0 0.83 10.3 0.0 2.2 2 0 0 2 2 2 0 PglD N-terminal domain Glyco_trans_1_4 PF13692.6 EMC94744.1 - 0.011 16.2 0.2 0.014 15.9 0.2 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EMC94744.1 - 0.088 12.3 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 MFS_1 PF07690.16 EMC94745.1 - 2.1e-12 46.6 70.0 5.2e-08 32.2 33.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_25 PF13649.6 EMC94746.1 - 6.1e-16 58.9 0.0 2e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC94746.1 - 1.5e-11 44.8 0.0 3.9e-11 43.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC94746.1 - 4.8e-11 42.7 0.0 6.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC94746.1 - 5.4e-09 36.7 0.0 1.3e-08 35.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC94746.1 - 8.9e-09 35.4 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMC94746.1 - 4.8e-06 26.5 0.0 7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EMC94746.1 - 1.3e-05 24.7 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EMC94746.1 - 3e-05 23.5 0.0 7.2e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMC94746.1 - 7.1e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EMC94746.1 - 8.6e-05 22.2 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 EMC94746.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 EMC94746.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0146 PF03686.13 EMC94746.1 - 0.0045 16.9 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) TPMT PF05724.11 EMC94746.1 - 0.0063 16.2 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 EMC94746.1 - 0.009 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) 3HCDH_N PF02737.18 EMC94746.1 - 0.0093 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_PK PF05891.12 EMC94746.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 EMC94746.1 - 0.033 14.2 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 EMC94746.1 - 0.035 13.7 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.7 EMC94746.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 EMC94746.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Bin3 PF06859.12 EMC94746.1 - 0.19 12.4 0.0 0.43 11.2 0.0 1.6 2 0 0 2 2 1 0 Bicoid-interacting protein 3 (Bin3) Beta-lactamase PF00144.24 EMC94747.1 - 5.6e-24 85.0 5.4 5.6e-24 85.0 5.4 2.4 2 1 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 EMC94747.1 - 7.8e-05 23.1 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF892 PF05974.12 EMC94748.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF5341 PF17276.2 EMC94748.1 - 0.032 14.4 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5341) AAA_3 PF07726.11 EMC94748.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NAD_binding_6 PF08030.12 EMC94749.1 - 5.3e-19 68.9 0.0 1.3e-10 41.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EMC94749.1 - 4.3e-18 65.6 16.7 4.3e-18 65.6 16.7 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMC94749.1 - 2.2e-13 50.2 0.3 9.1e-13 48.2 0.0 2.3 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EMC94749.1 - 0.0019 18.8 0.1 1.8 9.2 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Mg_trans_NIPA PF05653.14 EMC94750.1 - 2e-14 53.4 5.5 3.7e-14 52.5 5.5 1.4 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EMC94750.1 - 0.0025 18.0 0.4 0.0025 18.0 0.4 3.5 3 1 1 4 4 4 2 EamA-like transporter family Tmemb_55A PF09788.9 EMC94750.1 - 0.44 9.6 1.0 6.2 5.8 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A Fungal_trans_2 PF11951.8 EMC94751.1 - 3.7e-53 180.7 0.0 4.9e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC94751.1 - 4.2e-06 26.8 12.4 8.1e-06 25.9 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nrap_D2 PF17403.2 EMC94751.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain DUF4311 PF14188.6 EMC94751.1 - 0.18 11.5 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) EutQ PF06249.12 EMC94752.1 - 1.7e-09 37.6 0.0 2.2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EMC94752.1 - 7.1e-09 35.2 0.0 1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EMC94752.1 - 0.001 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain KduI PF04962.12 EMC94752.1 - 0.019 14.3 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Cupin_1 PF00190.22 EMC94752.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 EMC94752.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.3 1 1 0 1 1 1 0 Cupin fn3_2 PF16893.5 EMC94753.1 - 1.4e-36 124.5 0.0 2.2e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EMC94753.1 - 4.2e-24 84.2 0.4 7.5e-24 83.4 0.4 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EMC94753.1 - 1.3e-14 53.9 0.0 2.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EMC94753.1 - 1.2e-08 35.2 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 EMC94753.1 - 1.5e-06 28.3 0.0 6.4e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 EMC94753.1 - 0.00097 19.4 0.0 0.004 17.5 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 EMC94753.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain YbaB_DNA_bd PF02575.16 EMC94753.1 - 0.32 11.2 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family DUF4064 PF13273.6 EMC94755.1 - 0.095 13.0 0.0 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Tim17 PF02466.19 EMC94755.1 - 0.15 12.5 1.3 4.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Malate_synthase PF01274.22 EMC94756.1 - 3.5e-227 754.8 0.0 4e-227 754.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Holin_BhlA PF10960.8 EMC94757.1 - 0.2 11.6 0.0 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 BhlA holin family ArfA PF03889.13 EMC94758.1 - 0.013 14.9 1.8 0.037 13.5 1.8 1.8 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A DUF1687 PF07955.11 EMC94759.1 - 3.2e-31 108.5 0.0 4.2e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 EMC94759.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 ArsC family EF-hand_6 PF13405.6 EMC94763.1 - 1.2e-10 40.4 0.0 1.3e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EMC94763.1 - 2.5e-10 40.6 0.2 7.5e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EMC94763.1 - 1.4e-09 36.8 0.0 1.8e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EMC94763.1 - 8.8e-08 31.3 0.1 3.2e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EMC94763.1 - 0.00022 21.5 0.0 0.14 12.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EMC94763.1 - 0.02 14.7 0.2 0.5 10.2 0.1 2.5 2 1 1 3 3 3 0 EF-hand domain pair Abhydrolase_8 PF06259.12 EMC94764.1 - 0.092 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase MANEC PF07502.14 EMC94766.1 - 0.049 13.9 0.2 0.11 12.8 0.1 1.6 2 0 0 2 2 2 0 MANEC domain LAP1C PF05609.12 EMC94766.1 - 0.2 10.7 0.3 0.33 10.0 0.0 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) m04gp34like PF12216.8 EMC94767.1 - 0.013 15.1 0.3 0.024 14.2 0.3 1.3 1 0 0 1 1 1 0 Immune evasion protein TMEM119 PF15724.5 EMC94767.1 - 0.23 11.5 10.8 2.7 8.0 6.9 2.9 1 1 1 2 2 2 0 TMEM119 family DUF4690 PF15756.5 EMC94767.1 - 0.67 10.6 3.4 0.58 10.8 0.4 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage RIFIN PF02009.16 EMC94767.1 - 0.9 9.4 4.1 0.31 10.9 0.2 2.0 2 1 0 2 2 2 0 Rifin Mitofilin PF09731.9 EMC94771.1 - 9.1e-125 417.9 23.7 4.7e-108 362.7 19.5 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF3053 PF11254.8 EMC94771.1 - 0.1 12.1 11.3 0.28 10.7 8.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) SPX PF03105.19 EMC94771.1 - 0.36 10.7 22.1 1.1 9.1 21.7 1.7 1 1 0 1 1 1 0 SPX domain DUF2937 PF11157.8 EMC94771.1 - 0.81 9.4 3.8 2.9 7.6 3.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Hpt PF01627.23 EMC94771.1 - 1.6 9.1 8.8 0.73 10.1 0.1 3.9 3 1 0 3 3 3 0 Hpt domain ALMT PF11744.8 EMC94771.1 - 2.7 6.7 7.4 4.1 6.1 7.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Herpes_capsid PF06112.11 EMC94771.1 - 3.3 7.8 7.6 10 6.1 7.6 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Syntaxin-6_N PF09177.11 EMC94771.1 - 6.8 7.3 13.7 1.3e+02 3.2 10.9 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal YlqD PF11068.8 EMC94771.1 - 8.4 6.8 18.7 7.2 7.0 12.0 3.0 2 1 2 4 4 4 0 YlqD protein Bac_rhodopsin PF01036.18 EMC94772.1 - 5.2e-45 153.7 16.5 6.5e-45 153.4 16.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein RPEL PF02755.15 EMC94772.1 - 5e-17 61.0 5.0 6.5e-09 35.2 0.9 2.3 2 0 0 2 2 2 2 RPEL repeat TMEM208_SND2 PF05620.11 EMC94772.1 - 0.08 12.7 0.2 0.08 12.7 0.2 2.7 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF1772 PF08592.11 EMC94772.1 - 0.1 12.9 10.1 2.4 8.5 2.8 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) DUF3278 PF11683.8 EMC94772.1 - 0.11 12.6 0.1 0.11 12.6 0.1 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) MerC PF03203.14 EMC94772.1 - 1.7 9.1 12.0 5.8 7.4 6.2 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein DUF2516 PF10724.9 EMC94772.1 - 2.3 8.6 7.0 2.8 8.3 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) DHHC PF01529.20 EMC94772.1 - 2.3 8.3 5.6 1.9 8.6 0.0 2.6 2 1 0 2 2 2 0 DHHC palmitoyltransferase DUF3810 PF12725.7 EMC94772.1 - 3.9 6.7 6.8 11 5.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF4131 PF13567.6 EMC94772.1 - 6.9 6.3 8.3 0.52 9.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_PK PF05891.12 EMC94773.1 - 3.3e-72 242.6 0.0 3.8e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 EMC94773.1 - 0.00075 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC94773.1 - 0.11 13.2 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FMO-like PF00743.19 EMC94774.1 - 1.3e-10 40.3 0.0 4.4e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMC94774.1 - 7.4e-10 38.9 0.0 1.8e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC94774.1 - 1.1e-08 35.0 0.1 0.1 12.2 0.0 3.3 2 1 1 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMC94774.1 - 2.7e-08 33.4 0.0 4.1e-05 23.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC94774.1 - 3.5e-08 33.0 0.0 0.00045 19.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EMC94774.1 - 2.8e-07 30.1 0.0 4.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC94774.1 - 0.0028 17.6 0.3 0.67 9.9 0.0 3.2 2 2 0 2 2 2 1 FAD-NAD(P)-binding Acetyltransf_1 PF00583.25 EMC94775.1 - 1.1e-09 38.6 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC94775.1 - 7.3e-09 35.6 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC94775.1 - 1.4e-06 28.1 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EMC94775.1 - 1.9e-06 28.2 0.1 5.4e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMC94775.1 - 0.00026 21.1 0.0 0.00045 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC94775.1 - 0.0029 17.7 0.0 0.0045 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.22 EMC94776.1 - 2.3e-55 188.2 0.0 1.3e-54 185.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 SET PF00856.28 EMC94777.1 - 3.8e-11 43.7 0.0 1.2e-10 42.1 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-CRD PF17979.1 EMC94777.1 - 0.014 15.5 2.4 0.026 14.7 2.4 1.3 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-HIT PF04438.16 EMC94777.1 - 0.61 10.0 5.5 0.22 11.4 2.4 1.9 2 0 0 2 2 2 0 HIT zinc finger zf-TFIIB PF13453.6 EMC94779.1 - 0.023 14.0 0.2 0.044 13.1 0.2 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn_ribbon_SprT PF17283.2 EMC94779.1 - 0.04 13.8 2.4 0.086 12.8 2.4 1.6 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DUF4692 PF15763.5 EMC94779.1 - 0.32 11.4 1.7 0.47 10.9 0.4 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) HSP90 PF00183.18 EMC94781.1 - 4e-219 728.8 33.2 5.1e-219 728.5 33.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EMC94781.1 - 5e-14 52.8 0.1 9.4e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMC94781.1 - 2e-10 40.7 0.1 7.4e-10 38.8 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S10 PF00450.22 EMC94781.1 - 0.065 12.6 1.1 0.24 10.7 0.0 2.2 2 0 0 2 2 2 0 Serine carboxypeptidase DUF1676 PF07898.13 EMC94781.1 - 2.6 8.0 5.0 2.5 8.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) PH_9 PF15410.6 EMC94782.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain dsRBD2 PF17842.1 EMC94782.1 - 0.017 15.3 3.0 1.2 9.3 0.2 2.9 2 1 1 3 3 3 0 Double-stranded RNA binding domain 2 zf-C2H2 PF00096.26 EMC94783.1 - 2.8e-06 27.5 13.7 0.013 15.9 2.4 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC94783.1 - 0.0007 19.9 15.2 0.41 11.2 0.7 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC94783.1 - 0.0018 19.0 11.7 0.1 13.5 2.1 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 EMC94783.1 - 0.35 11.2 6.5 0.14 12.5 1.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DHH PF01368.20 EMC94784.1 - 0.00043 20.5 0.1 0.0007 19.8 0.1 1.3 1 0 0 1 1 1 1 DHH family ArAE_2_N PF10337.9 EMC94785.1 - 2.5e-43 148.8 26.5 1.4e-33 116.7 3.1 4.8 4 1 0 4 4 4 3 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EMC94785.1 - 3.8e-15 56.4 0.0 1.2e-14 54.8 0.0 1.9 1 1 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EMC94785.1 - 2.2e-13 50.5 18.9 2.2e-13 50.5 18.9 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like adh_short PF00106.25 EMC94789.1 - 6.4e-28 97.5 0.2 1.8e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC94789.1 - 5.9e-19 68.6 0.1 1.3e-15 57.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC94789.1 - 0.0092 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMC94789.1 - 0.039 13.3 0.0 0.22 10.9 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) RRN9 PF10680.9 EMC94790.1 - 1.4e-18 66.9 3.7 1.4e-18 66.9 3.7 2.8 4 0 0 4 4 4 1 RNA polymerase I specific transcription initiation factor IF4E PF01652.18 EMC94791.1 - 4.5e-55 185.8 0.6 5.6e-55 185.5 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NAT PF04768.13 EMC94792.1 - 1.3e-47 161.6 0.0 2.4e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EMC94792.1 - 3.4e-31 108.2 0.0 1.4e-30 106.3 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EMC94792.1 - 1.2e-28 100.4 0.1 2.4e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Amino acid kinase family Sacchrp_dh_NADP PF03435.18 EMC94792.1 - 0.035 14.4 0.0 0.1 12.9 0.0 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EMC94792.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAC PF01849.18 EMC94794.1 - 5.6e-24 83.9 0.2 1.1e-23 83.0 0.2 1.5 1 0 0 1 1 1 1 NAC domain FAD_binding_3 PF01494.19 EMC94795.1 - 1.1e-69 235.3 0.1 1.4e-69 235.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC94795.1 - 1.4e-08 34.7 0.1 7.8e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC94795.1 - 4.8e-06 26.0 0.7 0.0021 17.3 0.1 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC94795.1 - 3e-05 23.5 0.1 0.00021 20.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC94795.1 - 3.7e-05 23.9 0.1 0.00011 22.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC94795.1 - 5e-05 23.8 0.1 0.47 11.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC94795.1 - 0.00018 20.4 0.7 0.001 17.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EMC94795.1 - 0.00034 20.1 0.2 0.00062 19.2 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMC94795.1 - 0.0006 19.0 1.9 0.0038 16.3 0.2 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMC94795.1 - 0.0014 17.8 0.3 0.0031 16.7 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EMC94795.1 - 0.0015 17.7 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.17 EMC94795.1 - 0.0026 17.0 0.2 0.0072 15.6 0.1 1.7 1 1 1 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EMC94795.1 - 0.013 14.3 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Amino_oxidase PF01593.24 EMC94795.1 - 0.064 12.5 1.1 2.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase PARP PF00644.20 EMC94796.1 - 7.6e-55 185.5 0.1 2e-54 184.2 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EMC94796.1 - 2.8e-41 140.8 0.0 4.8e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EMC94796.1 - 3.6e-22 78.2 0.3 7.7e-22 77.2 0.3 1.6 1 0 0 1 1 1 1 WGR domain RNA_pol_Rpb6 PF01192.22 EMC94797.1 - 1.8e-16 59.8 0.1 2.8e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 EMC94797.1 - 0.021 14.8 0.1 0.03 14.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Mitoc_mL59 PF18126.1 EMC94798.1 - 0.99 9.7 7.7 0.46 10.8 3.9 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein mL59 TagF_N PF09867.9 EMC94799.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 TagF N-terminal domain, Type VI secretion system-associated UBA PF00627.31 EMC94801.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.26 EMC94802.1 - 5.8e-11 42.2 10.1 7.5e-05 23.0 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC94802.1 - 7.2e-09 35.7 8.7 0.00052 20.6 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMC94802.1 - 2.6e-06 27.6 10.1 0.00016 21.9 2.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMC94802.1 - 0.0022 18.3 1.6 0.19 12.1 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EMC94802.1 - 0.014 15.1 5.7 2.1 8.2 2.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EMC94802.1 - 0.094 12.7 4.9 1.4 9.0 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 EMC94802.1 - 0.21 12.0 8.6 0.72 10.3 2.0 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 EMC94802.1 - 0.3 10.9 2.5 11 5.9 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type BolA PF01722.18 EMC94802.1 - 0.41 11.0 1.1 3.2 8.1 0.3 2.2 1 1 1 2 2 2 0 BolA-like protein zf-met PF12874.7 EMC94802.1 - 0.97 9.9 2.9 2.6 8.6 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-AN1 PF01428.16 EMC94802.1 - 6 7.1 7.5 13 6.1 1.5 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger RPN2_C PF18004.1 EMC94804.1 - 6.3e-53 179.0 0.2 6.3e-53 179.0 0.2 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EMC94804.1 - 1.9e-43 144.7 17.8 2.1e-10 40.5 0.0 8.5 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EMC94804.1 - 4.4e-22 78.3 0.7 3.4e-15 56.2 0.0 5.3 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.22 EMC94804.1 - 4.3e-06 26.5 0.2 4.1 7.9 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EMC94804.1 - 4.6e-06 27.0 0.7 0.019 15.4 0.0 4.8 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 EMC94804.1 - 0.00047 20.2 0.1 0.29 11.2 0.1 3.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 EMC94804.1 - 0.01 16.3 0.3 15 6.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 EMC94804.1 - 0.2 12.4 5.7 6 7.8 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat mRNA_triPase PF02940.15 EMC94805.1 - 2e-41 142.1 0.0 2.1e-40 138.8 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain Spt5_N PF11942.8 EMC94806.1 - 2.2e-17 63.9 11.2 2.2e-17 63.9 11.2 4.6 2 1 2 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 EMC94806.1 - 9.3e-16 57.5 0.0 1.8e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 EMC94806.1 - 1.3e-10 41.7 33.2 0.00025 21.5 26.5 4.0 2 1 0 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 EMC94806.1 - 1.4e-06 28.0 23.5 0.0017 18.2 0.4 5.7 5 0 0 5 5 5 3 KOW motif DUF3912 PF13051.6 EMC94806.1 - 0.0058 16.9 1.1 0.031 14.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) Arabino_trans_N PF17689.1 EMC94806.1 - 0.27 11.4 0.7 3.2 7.9 0.1 2.4 2 0 0 2 2 2 0 Arabinosyltransferase concanavalin like domain TFIIF_alpha PF05793.12 EMC94806.1 - 0.4 9.2 33.8 0.73 8.4 33.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) COesterase PF00135.28 EMC94807.1 - 1.1e-67 229.1 0.9 8.3e-62 209.7 0.6 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC94807.1 - 0.00067 19.6 0.1 0.0041 17.0 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold ZZ PF00569.17 EMC94808.1 - 1.6e-11 43.8 3.4 2.7e-11 43.1 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 EMC94808.1 - 1.1e-07 30.8 2.6 0.014 14.9 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EMC94808.1 - 1.4e-06 27.7 4.0 0.0097 15.8 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EMC94808.1 - 2.5e-05 24.6 3.7 0.064 13.7 0.5 3.2 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EMC94808.1 - 0.0017 18.2 1.9 0.4 10.6 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EMC94808.1 - 0.025 14.1 4.6 0.45 10.1 0.1 3.2 3 0 0 3 3 3 0 EF hand Lipase_chap PF03280.14 EMC94808.1 - 0.031 14.2 0.3 0.07 13.1 0.3 1.5 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Cupin_1 PF00190.22 EMC94810.1 - 1.9e-11 43.8 0.1 2.6e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Cupin Atg31 PF09795.9 EMC94811.1 - 0.068 13.2 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 31 MFS_1 PF07690.16 EMC94812.1 - 2.3e-42 145.2 45.5 2.3e-42 145.2 45.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC94812.1 - 1.6e-12 47.1 6.7 1.6e-12 47.1 6.7 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter HlyIII PF03006.20 EMC94812.1 - 0.00023 20.9 3.9 0.00023 20.9 3.9 2.3 1 1 1 2 2 2 1 Haemolysin-III related Abhydrolase_6 PF12697.7 EMC94814.1 - 1.3e-14 55.3 3.0 1.3e-14 55.3 3.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC94814.1 - 1.7e-07 31.2 0.1 2.7e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC94814.1 - 4e-07 29.6 0.1 3.6e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EMC94814.1 - 4.4e-05 23.4 0.0 7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Exo_endo_phos PF03372.23 EMC94815.1 - 2e-07 30.7 1.2 3.3e-07 30.1 1.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fez1 PF06818.15 EMC94816.1 - 0.0013 19.3 4.0 0.0037 17.8 0.2 2.2 2 0 0 2 2 2 1 Fez1 FlxA PF14282.6 EMC94816.1 - 0.0068 16.4 1.5 0.023 14.7 1.5 1.9 1 0 0 1 1 1 1 FlxA-like protein DFF-C PF09033.10 EMC94816.1 - 0.034 14.0 0.2 0.034 14.0 0.2 2.1 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain Ribosomal_L36 PF00444.18 EMC94817.1 - 2.4e-19 69.2 9.9 3.9e-19 68.6 9.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 UQ_con PF00179.26 EMC94819.1 - 1e-46 158.1 0.0 1.1e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMC94819.1 - 1.6e-05 24.6 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EMC94819.1 - 0.074 12.9 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 UEV domain Zn_ribbon_17 PF17120.5 EMC94820.1 - 1.2e-09 37.7 10.8 2.4e-09 36.7 10.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EMC94820.1 - 0.00072 20.3 12.4 0.019 15.8 0.3 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC94820.1 - 0.0046 17.2 0.1 0.1 12.9 0.1 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-rbx1 PF12678.7 EMC94820.1 - 0.14 12.4 2.7 0.46 10.8 2.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EMC94820.1 - 0.64 10.4 9.0 1.6 9.1 9.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EMC94820.1 - 0.97 9.4 6.1 2.1 8.3 6.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EMC94820.1 - 8.6 6.6 8.0 17 5.6 8.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain TRI12 PF06609.13 EMC94822.1 - 2.5e-44 151.7 28.4 3.5e-44 151.2 28.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EMC94822.1 - 2.7e-22 79.2 50.5 2.7e-22 79.2 50.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC94822.1 - 1.4e-09 37.4 16.3 1.4e-09 37.4 16.3 3.4 4 0 0 4 4 4 2 Sugar (and other) transporter SRF-TF PF00319.18 EMC94823.1 - 3.5e-21 74.4 0.1 4.9e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Shisa PF13908.6 EMC94823.1 - 2.6 8.3 4.8 0.53 10.5 0.4 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator SEN1_N PF12726.7 EMC94826.1 - 6.9e-176 586.7 0.4 9.9e-176 586.2 0.4 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EMC94826.1 - 1.4e-72 244.7 0.7 1.4e-72 244.7 0.7 2.3 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 EMC94826.1 - 2.1e-62 210.3 0.0 4.8e-62 209.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMC94826.1 - 6.2e-09 35.9 0.7 2.7e-05 24.0 0.3 3.0 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 EMC94826.1 - 1.8e-07 31.0 1.4 2.4e-05 24.0 0.0 3.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EMC94826.1 - 1.8e-07 31.6 0.0 7.7e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EMC94826.1 - 0.00074 19.3 0.7 0.34 10.6 0.0 3.5 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EMC94826.1 - 0.047 13.7 0.2 0.58 10.1 0.2 2.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TnpV PF14198.6 EMC94826.1 - 0.14 12.1 1.2 0.5 10.4 1.2 1.9 1 0 0 1 1 1 0 Transposon-encoded protein TnpV CNOT1_HEAT PF16418.5 EMC94827.1 - 0.084 12.9 0.4 47 4.0 0.1 3.1 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 1 HEAT repeat vMSA PF00695.19 EMC94827.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Sugar_tr PF00083.24 EMC94828.1 - 2.5e-86 290.3 13.8 3e-86 290.1 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC94828.1 - 1.7e-28 99.6 16.1 3.4e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMC94828.1 - 0.73 8.0 6.0 0.19 9.9 0.1 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SIR2 PF02146.17 EMC94829.1 - 2.1e-30 105.9 0.0 3.2e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF726 PF05277.12 EMC94829.1 - 0.15 11.0 1.1 0.24 10.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Afi1 PF07792.12 EMC94830.1 - 8.5e-37 126.6 0.3 2.1e-36 125.3 0.1 1.8 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 EMC94830.1 - 1.2e-36 125.1 0.0 2.2e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EMC94830.1 - 2e-08 33.4 0.6 0.2 10.3 0.0 3.9 2 2 2 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.9 EMC94830.1 - 0.016 14.8 0.0 0.08 12.5 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) zf-met PF12874.7 EMC94831.1 - 0.085 13.3 3.0 1.6 9.2 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-TAZ PF02135.16 EMC94831.1 - 0.29 11.6 6.4 0.15 12.6 2.3 2.2 2 0 0 2 2 2 0 TAZ zinc finger zf-C2H2_4 PF13894.6 EMC94831.1 - 0.5 11.3 17.5 18 6.5 0.0 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMC94831.1 - 0.52 10.9 24.8 2.9 8.5 0.1 5.4 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EMC94831.1 - 1.1 9.7 5.6 12 6.3 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Methyltransf_23 PF13489.6 EMC94834.1 - 6.6e-15 55.3 0.0 9.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC94834.1 - 9.2e-13 48.7 0.0 1.9e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC94834.1 - 7.5e-12 45.3 0.0 1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC94834.1 - 9.3e-11 42.2 0.0 1.7e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC94834.1 - 3e-09 37.5 0.0 4.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC94834.1 - 1.3e-07 31.2 0.0 2.3e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EMC94834.1 - 0.0038 17.2 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EMC94834.1 - 0.0047 16.1 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase DUF2249 PF10006.9 EMC94834.1 - 0.068 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) MTS PF05175.14 EMC94834.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain zf-C2HC5 PF06221.13 EMC94835.1 - 8.4e-23 80.1 5.8 1.4e-22 79.4 5.8 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FAM176 PF14851.6 EMC94835.1 - 0.16 11.6 1.2 0.42 10.3 1.2 1.7 1 0 0 1 1 1 0 FAM176 family DUF2461 PF09365.10 EMC94838.1 - 2e-52 178.2 0.1 4e-35 121.7 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical protein (DUF2461) YL1 PF05764.13 EMC94838.1 - 0.012 15.8 3.7 0.012 15.8 3.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein TYW3 PF02676.14 EMC94839.1 - 3.4e-30 105.0 0.0 5.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 ABC_tran PF00005.27 EMC94840.1 - 4.8e-48 163.2 0.1 9.9e-27 94.1 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMC94840.1 - 5.5e-15 55.9 0.6 0.0026 17.6 0.0 4.5 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMC94840.1 - 7.1e-13 48.5 0.1 0.00052 19.5 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMC94840.1 - 9.8e-10 39.3 0.0 0.00018 22.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Chromo PF00385.24 EMC94840.1 - 5.2e-08 32.7 0.9 1.2e-07 31.6 0.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 EMC94840.1 - 3.4e-07 30.3 0.0 0.0033 17.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EMC94840.1 - 4e-07 29.7 0.6 0.0069 16.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMC94840.1 - 1.2e-06 28.5 0.0 0.0079 16.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 EMC94840.1 - 2.3e-05 24.4 0.4 0.032 14.2 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 EMC94840.1 - 0.00024 21.4 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EMC94840.1 - 0.00034 20.9 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EMC94840.1 - 0.00052 19.8 0.1 0.3 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EMC94840.1 - 0.00076 19.8 0.0 1.7 9.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase DUF87 PF01935.17 EMC94840.1 - 0.0014 18.8 1.2 0.17 12.0 0.1 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_18 PF13238.6 EMC94840.1 - 0.0014 19.1 0.3 0.26 11.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 EMC94840.1 - 0.0016 17.5 0.4 0.42 9.5 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EMC94840.1 - 0.0024 18.0 0.0 2.8 8.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EMC94840.1 - 0.0033 17.3 1.1 5.1 6.8 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EMC94840.1 - 0.0051 16.5 0.4 1.5 8.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain HEAT_2 PF13646.6 EMC94840.1 - 0.0061 16.9 0.4 0.049 14.0 0.0 2.9 2 0 0 2 2 1 1 HEAT repeats AAA_16 PF13191.6 EMC94840.1 - 0.0084 16.5 0.0 1.5 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Adaptin_N PF01602.20 EMC94840.1 - 0.009 14.6 0.1 0.015 13.9 0.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region AAA_27 PF13514.6 EMC94840.1 - 0.013 15.1 0.3 5.1 6.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 EMC94840.1 - 0.017 15.6 0.0 5.6 7.4 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMC94840.1 - 0.03 14.0 1.8 0.96 9.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 EMC94840.1 - 0.034 13.9 0.1 0.58 9.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 EMC94840.1 - 0.04 13.1 0.7 0.93 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 EMC94840.1 - 0.041 12.5 0.0 4.2 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EMC94840.1 - 0.041 13.9 0.0 0.72 9.9 0.0 2.7 3 0 0 3 3 2 0 Dynamin family Roc PF08477.13 EMC94840.1 - 0.042 14.1 0.0 6.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EMC94840.1 - 0.085 12.9 0.3 26 4.8 0.1 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EMC94840.1 - 0.1 12.7 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMC94840.1 - 0.11 12.0 0.1 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3584 PF12128.8 EMC94840.1 - 0.11 10.0 0.5 4.3 4.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Alginate_lyase2 PF08787.11 EMC94840.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Alginate lyase MukB PF04310.12 EMC94840.1 - 0.13 12.0 0.1 16 5.2 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal CLASP_N PF12348.8 EMC94840.1 - 0.15 11.6 0.0 1.9 8.0 0.0 2.6 3 0 0 3 3 3 0 CLASP N terminal cobW PF02492.19 EMC94840.1 - 0.17 11.4 0.4 21 4.7 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EMC94840.1 - 0.18 11.7 0.3 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain HEAT_EZ PF13513.6 EMC94840.1 - 0.83 10.2 3.7 10 6.7 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat Pil1 PF13805.6 EMC94843.1 - 1.7e-127 424.4 0.2 2.2e-127 424.0 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 EMC94843.1 - 0.035 13.5 1.8 0.054 12.9 1.0 1.6 1 1 1 2 2 2 0 FAM92 protein Glyco_hydro_3_C PF01915.22 EMC94844.1 - 3e-44 151.4 0.0 9.1e-44 149.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMC94844.1 - 7.1e-39 134.0 0.0 1e-38 133.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMC94844.1 - 2.2e-18 66.1 0.1 4e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Lactamase_B_2 PF12706.7 EMC94845.1 - 3.8e-05 23.3 0.1 6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMC94845.1 - 7.4e-05 22.8 1.5 0.00017 21.6 0.2 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EMC94845.1 - 0.071 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Antimicrobial_6 PF08036.11 EMC94845.1 - 0.14 12.2 1.5 0.57 10.3 0.7 2.4 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide adh_short_C2 PF13561.6 EMC94847.1 - 8.4e-52 176.1 0.0 1.1e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC94847.1 - 1.2e-43 148.8 0.2 1.7e-43 148.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC94847.1 - 2.2e-06 27.7 0.0 3.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC94847.1 - 0.0072 15.8 0.2 0.014 14.9 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3506 PF12014.8 EMC94848.1 - 3e-45 153.6 0.0 6.9e-44 149.2 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 EMC94848.1 - 3.1e-07 30.2 0.0 6.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC94848.1 - 0.00023 20.9 0.0 0.00061 19.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain EthD PF07110.11 EMC94850.1 - 0.0027 18.8 0.1 0.0045 18.1 0.1 1.4 1 1 0 1 1 1 1 EthD domain MFS_1 PF07690.16 EMC94852.1 - 4.7e-20 71.8 60.4 5.8e-18 64.9 38.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3431 PF11913.8 EMC94853.1 - 5.2e-86 287.9 0.0 7e-86 287.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Peptidase_C50 PF03568.17 EMC94854.1 - 8.2e-137 456.5 0.0 1.3e-136 455.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 RRM_1 PF00076.22 EMC94854.1 - 3.1e-19 68.6 0.0 7e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPN7 PF10602.9 EMC94854.1 - 0.018 14.8 0.7 0.054 13.2 0.1 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 RRM_5 PF13893.6 EMC94854.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.6 EMC94854.1 - 0.24 11.7 9.6 0.13 12.6 0.2 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat PTCB-BRCT PF12738.7 EMC94855.1 - 5.4e-05 23.0 0.4 0.00016 21.5 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 EMC94855.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.7 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EMC94855.1 - 0.024 15.0 0.2 0.095 13.1 0.2 1.8 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ANTH PF07651.16 EMC94855.1 - 0.096 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 ANTH domain HicA_toxin PF07927.12 EMC94855.1 - 0.2 11.7 1.7 0.36 10.9 0.1 2.3 2 1 1 3 3 3 0 HicA toxin of bacterial toxin-antitoxin, DAHP_synth_2 PF01474.16 EMC94857.1 - 1.1e-204 680.0 0.0 1.2e-204 679.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Amidase PF01425.21 EMC94858.1 - 2.9e-98 329.8 0.0 4.1e-98 329.3 0.0 1.2 1 0 0 1 1 1 1 Amidase POB3_N PF17292.2 EMC94859.1 - 7.4e-30 103.2 0.1 1.2e-28 99.3 0.0 2.6 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 EMC94859.1 - 2.6e-29 100.9 0.3 1.9e-28 98.1 0.0 2.5 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EMC94859.1 - 9.4e-26 90.1 0.1 9.7e-25 86.8 0.0 2.6 4 0 0 4 4 4 1 Histone chaperone Rttp106-like SRP-alpha_N PF04086.13 EMC94861.1 - 2.2e-69 234.6 1.8 5.1e-69 233.4 1.8 1.6 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EMC94861.1 - 1.4e-43 148.9 0.1 5e-43 147.0 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EMC94861.1 - 1e-08 35.3 0.0 2.2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EMC94861.1 - 0.00019 20.5 0.2 0.00052 19.1 0.2 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EMC94861.1 - 0.012 15.4 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 EMC94861.1 - 0.018 14.9 0.0 0.064 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EMC94861.1 - 0.059 13.7 0.2 0.2 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 EMC94861.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 EMC94861.1 - 0.13 12.7 0.0 0.39 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain YIF1 PF03878.15 EMC94862.1 - 8e-101 336.5 2.5 9.6e-101 336.3 2.5 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EMC94862.1 - 0.0018 18.0 5.8 0.0018 18.0 5.8 1.7 2 0 0 2 2 2 1 Yip1 domain Peptidase_A22B PF04258.13 EMC94863.1 - 1.2e-62 212.0 0.1 2.6e-62 210.9 0.1 1.5 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EMC94863.1 - 9.5e-07 28.6 5.5 1.1e-06 28.4 0.8 2.3 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease DUF1440 PF07274.12 EMC94863.1 - 0.18 12.2 0.8 1.9 8.8 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1440) Pox_A14 PF05767.12 EMC94863.1 - 0.22 11.7 0.8 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 HET PF06985.11 EMC94864.1 - 5.2e-22 78.8 0.1 6.2e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5354 PF17305.2 EMC94865.1 - 0.043 14.0 0.3 0.043 14.0 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5354) NACHT PF05729.12 EMC94867.1 - 2.1e-10 40.8 0.0 7.4e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMC94867.1 - 4.3e-05 23.8 0.0 0.00017 21.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC94867.1 - 8e-05 23.1 0.0 0.00025 21.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EMC94867.1 - 0.0045 17.4 0.0 0.025 15.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EMC94867.1 - 0.0055 16.0 0.1 2.3 7.4 0.0 2.1 2 0 0 2 2 2 2 KAP family P-loop domain AAA_18 PF13238.6 EMC94867.1 - 0.0056 17.2 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMC94867.1 - 0.018 15.6 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CobU PF02283.16 EMC94867.1 - 0.019 14.5 0.1 0.69 9.5 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RNA_helicase PF00910.22 EMC94867.1 - 0.029 14.7 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Cys_rich_VLP PF14194.6 EMC94867.1 - 0.059 13.5 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP AAA_33 PF13671.6 EMC94867.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMC94867.1 - 0.12 12.0 0.0 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EMC94867.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF1772 PF08592.11 EMC94868.1 - 3.3e-18 66.3 6.0 9.1e-18 64.9 5.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) AMP-binding PF00501.28 EMC94869.1 - 3.4e-53 180.8 0.0 4.7e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EMC94869.1 - 2.7e-05 24.0 0.0 8.3e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EMC94869.1 - 0.0025 18.7 0.0 0.0072 17.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40_like PF17005.5 EMC94870.1 - 0.00089 18.7 0.0 0.067 12.5 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 EMC94870.1 - 0.02 15.2 0.0 4.8 7.6 0.0 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMC94870.1 - 0.31 12.0 6.2 7.7 7.6 0.1 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Methyltransf_2 PF00891.18 EMC94871.1 - 4.1e-20 72.0 0.0 6.6e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EMC94871.1 - 0.00017 21.6 2.0 0.0016 18.5 0.1 2.6 2 1 0 2 2 2 1 Dimerisation domain Methyltransf_31 PF13847.6 EMC94871.1 - 0.022 14.6 0.0 0.12 12.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Tom37 PF10568.9 EMC94872.1 - 2.6e-25 89.1 0.1 3.8e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EMC94872.1 - 1.3e-15 56.9 0.1 4.4e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMC94872.1 - 1.8e-05 24.7 0.0 4.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC94872.1 - 0.0027 17.9 0.0 0.0048 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMC94872.1 - 0.0047 17.1 0.1 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 EMC94874.1 - 9.6e-06 26.2 0.0 1.2e-05 26.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC94874.1 - 1.4e-05 24.9 0.0 1.7e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC94874.1 - 6.6e-05 22.5 0.0 6.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EMC94874.1 - 0.00014 22.4 0.0 0.00018 22.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EMC94874.1 - 0.00021 20.7 0.0 0.00022 20.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EMC94874.1 - 0.00095 19.0 0.0 0.00097 19.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC94874.1 - 0.0057 17.4 0.0 0.007 17.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMC94874.1 - 0.0073 15.8 0.0 0.009 15.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EMC94874.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EMC94874.1 - 0.037 14.1 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 EMC94874.1 - 0.044 13.7 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EMC94874.1 - 0.056 12.8 0.0 0.064 12.6 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EMC94874.1 - 0.085 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EMC94874.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EMC94874.1 - 0.13 11.3 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 EMC94874.1 - 0.16 11.7 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase ANTH PF07651.16 EMC94875.1 - 2.3e-59 200.7 0.1 3.6e-59 200.0 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EMC94875.1 - 0.0012 18.9 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.20 EMC94876.1 - 1.1e-92 310.5 0.0 1.4e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EMC94876.1 - 0.0034 16.9 0.3 0.012 15.1 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 EMC94876.1 - 0.026 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Aldedh PF00171.22 EMC94877.1 - 9.4e-183 607.9 1.1 1.1e-182 607.7 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMC94877.1 - 0.0058 16.1 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) TAXi_C PF14541.6 EMC94877.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Abhydrolase_1 PF00561.20 EMC94878.1 - 4.7e-27 95.2 0.0 9.3e-19 68.1 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC94878.1 - 2.2e-20 73.0 0.1 4.5e-20 71.9 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMC94878.1 - 3e-18 67.2 0.0 3.6e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EMC94878.1 - 0.00046 19.9 0.1 0.0044 16.7 0.1 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EMC94878.1 - 0.0059 15.3 0.3 0.042 12.5 0.1 2.0 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 EMC94878.1 - 0.02 15.0 0.0 0.69 10.1 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein Ndr PF03096.14 EMC94878.1 - 0.021 13.6 0.0 0.7 8.5 0.0 2.1 1 1 0 1 1 1 0 Ndr family Esterase PF00756.20 EMC94878.1 - 0.022 14.4 0.5 0.091 12.4 0.3 2.2 1 1 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 EMC94878.1 - 0.023 14.2 0.1 0.19 11.2 0.1 2.4 2 2 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 EMC94878.1 - 0.041 13.4 0.2 0.24 10.9 0.0 2.2 2 1 1 3 3 3 0 Dienelactone hydrolase family Methyltransf_23 PF13489.6 EMC94879.1 - 1.3e-21 77.1 0.0 1.8e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC94879.1 - 2.1e-15 56.8 0.0 6.7e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC94879.1 - 2.2e-15 57.2 0.0 5.4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC94879.1 - 2.3e-15 57.2 0.0 5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC94879.1 - 7.9e-14 52.1 0.0 2.1e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC94879.1 - 5e-07 29.3 0.0 3.6e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 EMC94879.1 - 9.3e-05 22.1 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) DREV PF05219.12 EMC94879.1 - 0.00027 20.1 0.0 0.00059 19.0 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase MTS PF05175.14 EMC94879.1 - 0.0004 20.0 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EMC94879.1 - 0.00091 18.7 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EMC94879.1 - 0.002 17.9 0.0 0.0039 17.0 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 EMC94879.1 - 0.002 17.9 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.20 EMC94879.1 - 0.0042 16.2 0.0 0.0054 15.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EMC94879.1 - 0.0088 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EMC94879.1 - 0.033 14.2 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EMC94879.1 - 0.039 13.3 0.0 0.62 9.4 0.0 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 EMC94879.1 - 0.067 12.2 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Bmt2 PF11968.8 EMC94879.1 - 0.19 11.6 0.0 19 5.0 0.0 2.8 3 0 0 3 3 3 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 DUF1772 PF08592.11 EMC94883.1 - 6.9e-23 81.5 0.5 8.9e-23 81.1 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Lactamase_B PF00753.27 EMC94885.1 - 0.00021 21.4 0.1 0.00038 20.5 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMC94885.1 - 0.023 14.2 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pkinase PF00069.25 EMC94886.1 - 8.6e-75 251.5 0.0 9.8e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC94886.1 - 1.2e-36 126.4 0.0 1.6e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMC94886.1 - 0.00019 20.5 0.0 0.0011 18.0 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMC94886.1 - 0.019 14.9 0.7 0.022 14.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EMC94886.1 - 0.025 13.9 0.1 0.077 12.3 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMC94886.1 - 0.073 12.4 0.1 0.21 10.9 0.0 1.7 1 1 1 2 2 2 0 Kinase-like CBP4 PF07960.11 EMC94887.1 - 2.7e-28 98.4 2.2 2.9e-28 98.3 2.2 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 EMC94887.1 - 0.014 15.3 0.1 0.048 13.6 0.0 1.8 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 ERCC4 PF02732.15 EMC94889.1 - 2.3e-18 66.9 0.0 4.8e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_2 PF12826.7 EMC94889.1 - 0.065 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif PIG-U PF06728.13 EMC94890.1 - 2.4e-107 359.3 19.2 2.8e-107 359.1 19.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.11 EMC94891.1 - 4.9e-123 410.0 0.0 4.9e-123 410.0 0.0 1.5 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EMC94891.1 - 0.0014 19.0 0.0 0.0053 17.1 0.0 2.0 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Acetyltransf_1 PF00583.25 EMC94892.1 - 3.8e-11 43.3 0.0 4.4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC94892.1 - 6.9e-06 26.0 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC94892.1 - 0.00017 21.9 0.0 0.00022 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC94892.1 - 0.00035 20.5 0.0 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EMC94892.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 EMC94893.1 - 4.5e-14 52.2 0.1 8.1e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EMC94893.1 - 0.0013 19.5 0.1 0.0019 18.9 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like tRNA-synt_1b PF00579.25 EMC94894.1 - 6.1e-71 239.1 0.0 8e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EMC94894.1 - 2.8e-37 127.2 0.0 5.3e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 EMC94894.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 S4 domain ADH_zinc_N PF00107.26 EMC94895.1 - 8e-21 74.4 1.3 1.7e-20 73.3 1.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC94895.1 - 6.1e-11 43.5 0.1 1.1e-10 42.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 EMC94895.1 - 0.096 12.9 1.7 0.74 10.0 0.7 2.4 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HopW1-1 PF15457.6 EMC94898.1 - 0.013 14.7 0.2 0.018 14.3 0.2 1.1 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Med9 PF07544.13 EMC94898.1 - 0.047 13.8 0.1 0.076 13.1 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 zf-C2H2 PF00096.26 EMC94901.1 - 4.4e-31 105.6 46.0 0.00015 22.0 0.3 10.9 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC94901.1 - 4.7e-22 76.8 42.8 0.078 13.9 0.5 11.1 11 0 0 11 11 11 7 C2H2-type zinc finger FOXP-CC PF16159.5 EMC94901.1 - 6.5e-11 42.7 29.7 0.00083 19.9 0.4 8.7 6 3 4 10 10 10 3 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 EMC94901.1 - 2.6e-10 40.2 45.7 1.1e-05 25.7 0.1 10.8 10 1 0 10 10 10 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMC94901.1 - 1.3e-07 31.7 16.3 0.31 11.4 0.0 8.2 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 EMC94901.1 - 2.2e-05 24.1 9.6 0.77 9.5 0.1 6.3 6 0 0 6 6 6 2 C2H2 Hakai zinc finger domain zf-C2H2_8 PF15909.5 EMC94901.1 - 0.0019 18.5 15.1 0.13 12.6 0.2 4.7 5 2 1 6 6 6 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 EMC94901.1 - 0.0064 16.2 8.4 4.7 7.1 0.0 5.6 5 0 0 5 5 5 1 zinc-finger C2H2-type zf-Di19 PF05605.12 EMC94901.1 - 0.017 15.4 38.2 0.79 10.1 3.0 8.5 7 2 3 10 10 10 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 EMC94901.1 - 0.11 13.2 18.3 3.1 8.5 1.2 5.1 5 1 0 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 EMC94901.1 - 0.14 12.3 17.4 23 5.2 0.1 7.2 5 1 3 8 8 8 0 Zic proteins zinc finger domain Ogr_Delta PF04606.12 EMC94901.1 - 0.33 11.0 11.4 1.6 8.8 0.1 5.0 2 1 3 5 5 5 0 Ogr/Delta-like zinc finger zf-C2H2_aberr PF17017.5 EMC94901.1 - 0.33 11.1 14.1 5 7.2 0.0 5.2 5 2 2 7 7 7 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 EMC94901.1 - 0.41 10.5 0.0 0.41 10.5 0.0 9.4 11 0 0 11 11 10 0 C2H2-type zinc-finger domain IBR PF01485.21 EMC94901.1 - 8.2 6.7 16.3 1.4 9.2 0.9 4.5 3 2 1 4 4 4 0 IBR domain, a half RING-finger domain PMI_typeI PF01238.21 EMC94904.1 - 4.7e-69 233.4 0.0 5e-68 230.0 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EMC94904.1 - 0.00051 19.7 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EMC94904.1 - 0.099 12.6 0.0 0.94 9.4 0.0 2.2 2 0 0 2 2 2 0 AraC-like ligand binding domain RIBIOP_C PF04950.12 EMC94905.1 - 7.4e-106 353.8 0.0 1e-105 353.4 0.0 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EMC94905.1 - 3.4e-16 59.1 0.1 5.1e-15 55.3 0.1 2.5 1 1 0 1 1 1 1 AARP2CN (NUC121) domain HMGL-like PF00682.19 EMC94906.1 - 1.5e-30 106.6 0.0 1.9e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 HMGL-like DUF362 PF04015.12 EMC94906.1 - 0.022 15.0 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF362) IL3 PF02059.15 EMC94906.1 - 0.022 14.8 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Interleukin-3 AAA_18 PF13238.6 EMC94907.1 - 0.00073 20.1 0.0 0.0024 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EMC94907.1 - 0.0012 18.6 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 EMC94907.1 - 0.0019 18.0 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EMC94907.1 - 0.008 16.3 0.0 0.086 13.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain Cytochrom_B561 PF03188.16 EMC94910.1 - 0.0006 20.0 15.6 0.0006 20.0 15.6 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EMC94910.1 - 0.0077 16.0 11.6 0.0077 16.0 11.6 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) RCR PF12273.8 EMC94910.1 - 0.23 12.1 1.5 0.54 10.9 1.5 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4079 PF13301.6 EMC94910.1 - 1.2 9.3 17.4 1.7 8.8 9.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) PalH PF08733.10 EMC94910.1 - 2.3 7.1 6.8 3.2 6.7 6.8 1.2 1 0 0 1 1 1 0 PalH/RIM21 Steroid_dh PF02544.16 EMC94911.1 - 7.4e-33 113.7 0.7 1e-32 113.2 0.7 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EMC94911.1 - 0.00056 20.3 0.4 0.0013 19.1 0.4 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 EMC94911.1 - 0.0027 17.3 0.3 0.0038 16.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) An_peroxidase PF03098.15 EMC94912.1 - 6.4e-35 120.7 0.0 2.3e-22 79.3 0.0 4.1 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 EMC94912.1 - 1.7e-05 23.8 0.0 4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_A_bac PF01000.26 EMC94913.1 - 1.9e-29 102.3 0.0 3.5e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EMC94913.1 - 2.5e-14 52.5 0.0 3.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RCC1 PF00415.18 EMC94914.1 - 1.2e-14 54.6 3.2 1.8e-05 25.3 0.0 3.9 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMC94914.1 - 1.3e-08 34.4 5.1 0.00049 19.8 0.1 3.5 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Amino_oxidase PF01593.24 EMC94915.1 - 1.1e-16 61.1 0.1 4.5e-15 55.9 0.0 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMC94915.1 - 3.4e-15 56.0 0.0 7.6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMC94915.1 - 3.8e-05 22.9 0.1 9.6e-05 21.6 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC94915.1 - 0.00012 21.5 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC94915.1 - 0.00012 21.8 0.0 0.00032 20.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC94915.1 - 0.0024 16.6 0.0 0.0037 16.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EMC94915.1 - 0.006 17.1 0.0 0.02 15.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMC94915.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EMC94915.1 - 0.016 14.3 0.1 0.028 13.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EMC94915.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC94915.1 - 0.032 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family IlvN PF07991.12 EMC94915.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 EMC94915.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding V-SNARE PF05008.15 EMC94916.1 - 5e-19 68.5 4.2 5e-19 68.5 4.2 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EMC94916.1 - 1.8e-16 60.1 5.0 1.8e-16 60.1 5.0 2.9 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EMC94916.1 - 0.017 15.0 2.7 0.09 12.7 0.3 2.4 2 0 0 2 2 2 0 Sec20 DUF1542 PF07564.11 EMC94916.1 - 0.085 13.0 2.4 0.12 12.5 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Fusion_gly PF00523.18 EMC94916.1 - 0.086 11.1 3.1 0.054 11.7 0.5 1.8 2 0 0 2 2 2 0 Fusion glycoprotein F0 DUF4407 PF14362.6 EMC94916.1 - 0.1 11.9 11.5 0.31 10.4 11.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Orf78 PF06024.12 EMC94916.1 - 0.21 11.9 1.1 0.38 11.1 0.0 1.9 2 1 0 2 2 2 0 Orf78 (ac78) Atg14 PF10186.9 EMC94916.1 - 0.22 10.6 10.5 0.35 9.9 10.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FtsX_ECD PF18075.1 EMC94916.1 - 0.26 11.9 2.7 0.23 12.1 1.2 1.7 2 0 0 2 2 2 0 FtsX extracellular domain Spectrin PF00435.21 EMC94916.1 - 0.37 11.3 6.1 0.49 10.9 2.2 2.6 1 1 2 3 3 3 0 Spectrin repeat Synaptobrevin PF00957.21 EMC94916.1 - 0.4 10.5 3.9 0.29 11.0 1.4 2.1 2 1 0 2 2 2 0 Synaptobrevin DUF1741 PF08427.10 EMC94917.1 - 1.6e-74 250.5 0.6 2.8e-74 249.7 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DUF2178 PF09946.9 EMC94917.1 - 0.095 12.9 0.9 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) DUF726 PF05277.12 EMC94918.1 - 4.8e-123 410.4 4.1 7.3e-123 409.8 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EMC94918.1 - 0.00049 20.3 0.9 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 EMC94918.1 - 0.035 13.4 0.0 0.08 12.2 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MIOX PF05153.15 EMC94919.1 - 1.4e-120 401.5 0.5 1.4e-120 401.5 0.5 1.4 2 0 0 2 2 2 1 Myo-inositol oxygenase Cytochrom_C_2 PF01322.20 EMC94919.1 - 0.014 16.3 1.8 0.027 15.4 1.8 1.5 1 0 0 1 1 1 0 Cytochrome C' HD PF01966.22 EMC94919.1 - 0.026 14.7 0.0 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 HD domain DUF1796 PF08795.10 EMC94919.1 - 0.043 13.8 0.3 0.062 13.3 0.3 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) UBD PF16455.5 EMC94919.1 - 0.075 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain adh_short_C2 PF13561.6 EMC94921.1 - 5.6e-56 189.7 0.0 7.2e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC94921.1 - 1e-54 185.0 0.0 1.3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC94921.1 - 7.4e-13 48.8 0.1 1.1e-12 48.2 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC94921.1 - 8.1e-05 22.2 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 EMC94921.1 - 0.015 15.0 0.0 0.12 12.1 0.0 2.2 2 1 1 3 3 3 0 Starch synthase catalytic domain RmlD_sub_bind PF04321.17 EMC94921.1 - 0.066 12.3 0.6 0.19 10.8 0.1 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 EMC94921.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Toprim_3 PF13362.6 EMC94921.1 - 0.25 11.7 2.4 1.5 9.3 0.5 2.8 2 2 1 3 3 3 0 Toprim domain ADH_N PF08240.12 EMC94922.1 - 1.4e-28 99.0 0.1 3.1e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC94922.1 - 5.3e-20 71.7 0.2 1.1e-19 70.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMC94922.1 - 9.3e-09 35.1 0.2 0.00051 19.6 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EMC94922.1 - 0.0018 17.6 0.3 0.0029 17.0 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EMC94922.1 - 0.0039 18.2 0.0 0.0099 16.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EMC94922.1 - 0.054 13.1 0.2 0.091 12.3 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 EMC94922.1 - 0.067 12.3 0.4 0.09 11.8 0.4 1.1 1 0 0 1 1 1 0 FAD binding domain AdoHcyase_NAD PF00670.21 EMC94922.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.14 EMC94922.1 - 0.18 10.5 1.9 0.26 10.0 1.9 1.2 1 0 0 1 1 1 0 HI0933-like protein Tudor_2 PF18104.1 EMC94923.1 - 0.02 14.6 0.3 0.039 13.6 0.3 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Aldo_ket_red PF00248.21 EMC94925.1 - 1e-45 156.2 0.0 1.6e-43 149.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family CENP-S PF15630.6 EMC94926.1 - 5.3e-28 97.2 0.0 6.6e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EMC94926.1 - 1.4e-06 28.3 0.0 1.7e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF815 PF05673.13 EMC94926.1 - 0.085 12.0 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Myotub-related PF06602.14 EMC94927.1 - 1.3e-126 422.3 0.0 1.6e-126 422.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EMC94927.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF913 PF06025.12 EMC94928.1 - 2.8e-108 362.2 0.0 2.8e-108 362.2 0.0 6.4 7 2 0 7 7 7 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EMC94928.1 - 1.2e-95 321.0 0.6 1.2e-95 321.0 0.6 4.1 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EMC94928.1 - 2.3e-95 319.6 0.1 3.7e-95 319.0 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EMC94928.1 - 3.4e-22 77.1 31.9 4.7e-09 35.4 2.3 5.1 4 1 1 5 5 5 3 Ubiquitin binding region DASH_Dad1 PF08649.10 EMC94928.1 - 0.12 12.5 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad1 PV-1 PF06637.11 EMC94928.1 - 1.7 7.4 15.1 3.7 6.3 15.1 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) V_ATPase_I PF01496.19 EMC94928.1 - 2.2 6.1 5.2 5 4.9 5.2 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 EMC94928.1 - 3.9 7.2 6.6 11 5.7 6.6 1.7 1 0 0 1 1 1 0 Connexin HpcH_HpaI PF03328.14 EMC94930.1 - 1.6e-39 135.3 0.0 3.8e-39 134.1 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EMC94930.1 - 2.7e-12 46.5 0.0 3.7e-06 26.3 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.12 EMC94931.1 - 1.9e-51 173.8 6.4 2.2e-51 173.5 6.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5504 PF17608.2 EMC94931.1 - 0.039 14.1 0.6 0.039 14.1 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5504) TMEM220 PF15071.6 EMC94931.1 - 0.15 12.9 2.4 0.2 12.4 0.5 1.9 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF4191 PF13829.6 EMC94931.1 - 0.46 9.8 5.6 5 6.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) CCB1 PF12046.8 EMC94931.1 - 5 6.4 6.8 0.83 9.0 0.8 2.0 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B AMP-binding PF00501.28 EMC94932.1 - 1.6e-83 280.7 0.0 2e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC94932.1 - 6.5e-13 49.5 0.0 1.8e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CBM_1 PF00734.18 EMC94934.1 - 4e-12 45.9 15.7 1.4e-11 44.1 15.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DPBB_1 PF03330.18 EMC94934.1 - 0.0031 17.8 0.1 0.0031 17.8 0.1 2.4 3 0 0 3 3 3 1 Lytic transglycolase Myticin-prepro PF10690.9 EMC94934.1 - 0.25 11.6 5.0 0.16 12.2 2.1 2.1 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel DUF2406 PF10295.9 EMC94936.1 - 5e-22 78.4 0.1 1.4e-21 77.0 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.10 EMC94937.1 - 3.8e-15 55.7 9.6 5.5e-15 55.2 9.6 1.3 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 EMC94938.1 - 8.2e-52 176.1 0.0 1.4e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC94938.1 - 9.1e-18 64.6 0.0 1.1e-15 58.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC94938.1 - 2.6e-10 40.5 0.0 7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMC94938.1 - 0.00012 21.4 0.0 0.00085 18.6 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 EMC94938.1 - 0.016 14.9 0.0 2.9 7.5 0.0 3.5 4 0 0 4 4 4 0 DEAD_2 NAD_binding_10 PF13460.6 EMC94938.1 - 0.018 15.0 0.1 0.053 13.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H-binding UBA PF00627.31 EMC94938.1 - 0.018 14.9 0.0 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain AAA_22 PF13401.6 EMC94938.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain ATR13 PF16829.5 EMC94938.1 - 0.054 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector HIGH_NTase1_ass PF16581.5 EMC94938.1 - 0.084 12.9 0.2 0.39 10.7 0.0 2.1 3 0 0 3 3 3 0 Cytidyltransferase-related C-terminal region PVL_ORF50 PF07768.11 EMC94938.1 - 0.3 11.4 2.0 0.65 10.3 0.1 2.6 2 0 0 2 2 2 0 PVL ORF-50-like family Rab5ip PF07019.12 EMC94939.1 - 1.7e-27 95.8 6.7 2e-27 95.6 6.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.7 EMC94941.1 - 1.1e-73 248.0 0.0 2.4e-73 246.9 0.0 1.5 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes DASH_Hsk3 PF08227.11 EMC94941.1 - 0.0051 17.1 0.3 1.1 9.7 0.2 3.1 3 0 0 3 3 3 1 DASH complex subunit Hsk3 like Cluap1 PF10234.9 EMC94941.1 - 0.088 12.2 0.2 0.088 12.2 0.2 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 Polysacc_synt_C PF14667.6 EMC94941.1 - 0.2 11.7 4.6 0.36 10.9 4.6 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain TMF_TATA_bd PF12325.8 EMC94941.1 - 6.5 7.0 9.3 0.39 11.0 2.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sec20 PF03908.13 EMC94942.1 - 4e-15 55.5 0.4 4e-15 55.5 0.4 3.6 4 1 1 5 5 5 1 Sec20 ArAE_2 PF10334.9 EMC94942.1 - 0.44 10.3 0.0 0.44 10.3 0.0 2.2 3 0 0 3 3 3 0 Aromatic acid exporter family member 2 COMP PF11598.8 EMC94942.1 - 1.6 9.3 3.9 0.72 10.4 0.6 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Sec63 PF02889.16 EMC94943.1 - 7.6e-167 552.9 1.9 1.2e-92 309.7 0.0 3.2 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 EMC94943.1 - 1e-41 142.6 0.1 2.1e-26 92.8 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EMC94943.1 - 1.9e-29 102.1 1.9 2.7e-29 101.6 0.2 2.2 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 EMC94943.1 - 1.3e-16 61.1 0.0 1.2e-11 44.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMC94943.1 - 4.4e-13 49.5 0.0 1.9e-08 34.6 0.0 4.1 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EMC94943.1 - 0.0016 18.7 0.2 0.16 12.2 0.1 3.2 2 1 0 2 2 2 1 AAA domain TFIIE_alpha PF02002.17 EMC94943.1 - 0.078 12.8 0.6 15 5.5 0.0 4.0 3 0 0 3 3 3 0 TFIIE alpha subunit T2SSE PF00437.20 EMC94943.1 - 0.11 11.6 0.0 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF4407 PF14362.6 EMC94944.1 - 1.9 7.8 14.5 0.8 9.0 1.6 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) PWWP PF00855.17 EMC94945.1 - 4.9e-19 68.5 0.0 4.9e-19 68.5 0.0 3.1 3 0 0 3 3 3 1 PWWP domain Phos_pyr_kin PF08543.12 EMC94950.1 - 1.9e-09 37.3 0.0 6.7e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EMC94950.1 - 6.2e-06 25.7 0.0 7.5e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 pfkB family carbohydrate kinase PCNA_N PF00705.18 EMC94951.1 - 1e-54 183.6 5.7 1e-54 183.6 5.7 2.0 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EMC94951.1 - 1e-52 177.6 0.1 1.2e-51 174.2 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EMC94951.1 - 1.3e-09 37.9 0.3 1.5e-09 37.7 0.3 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EMC94951.1 - 7.2e-05 22.0 0.8 0.029 13.4 0.1 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 EMC94951.1 - 0.00061 19.0 0.9 0.0017 17.5 0.3 1.9 2 1 0 2 2 2 1 Hus1-like protein FAD-oxidase_C PF02913.19 EMC94951.1 - 0.067 12.8 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain GTP_EFTU PF00009.27 EMC94952.1 - 5.2e-46 156.6 0.0 8.1e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EMC94952.1 - 1.8e-34 118.9 8.1 3.6e-34 118.0 8.1 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EMC94952.1 - 2.7e-22 78.8 0.0 5.9e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EMC94952.1 - 7.7e-17 61.1 0.0 2e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMC94952.1 - 1.1e-11 44.9 0.1 3.2e-11 43.5 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EMC94952.1 - 8.1e-07 29.0 0.0 2.9e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EMC94952.1 - 0.0013 18.8 0.0 0.0038 17.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EMC94952.1 - 0.09 12.2 0.1 0.83 9.1 0.1 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EMC94952.1 - 0.19 11.9 0.0 20 5.5 0.0 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Thiolase_N PF00108.23 EMC94953.1 - 3.3e-92 308.5 0.9 8.5e-92 307.2 0.2 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMC94953.1 - 1.8e-45 153.6 1.3 1.8e-45 153.6 1.3 2.1 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMC94953.1 - 8.9e-05 22.2 5.5 0.00011 21.8 2.9 2.4 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EMC94953.1 - 0.00063 19.6 4.9 0.015 15.2 0.4 3.1 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 EMC94953.1 - 0.018 13.8 0.8 0.047 12.4 0.3 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) DUF202 PF02656.15 EMC94954.1 - 4.1e-06 27.2 1.1 4.1e-06 27.2 1.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cation_efflux PF01545.21 EMC94955.1 - 4.6e-49 166.9 14.5 4.4e-48 163.7 14.5 2.0 1 1 0 1 1 1 1 Cation efflux family Eno-Rase_NADH_b PF12242.8 EMC94955.1 - 0.033 13.9 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CitMHS PF03600.16 EMC94955.1 - 0.14 11.3 1.9 0.77 8.9 1.1 2.0 2 0 0 2 2 2 0 Citrate transporter DUF846 PF05832.12 EMC94955.1 - 3 7.9 9.4 0.1 12.7 3.1 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) CFEM PF05730.11 EMC94958.1 - 2.8e-09 36.9 3.9 3e-09 36.8 3.9 1.0 1 0 0 1 1 1 1 CFEM domain zf-MYND PF01753.18 EMC94960.1 - 1.3e-12 47.6 71.2 0.0023 18.0 6.0 7.2 6 2 0 6 6 6 6 MYND finger Vps39_2 PF10367.9 EMC94962.1 - 5.7e-30 104.0 0.0 1.7e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EMC94962.1 - 3.3e-27 94.9 0.0 2.8e-26 91.9 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 EMC94962.1 - 9.5e-13 48.4 0.0 6.1e-12 45.7 0.0 2.0 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 EMC94962.1 - 0.00025 20.9 0.3 0.00084 19.2 0.3 1.9 1 0 0 1 1 1 1 Region in Clathrin and VPS TBX PF12598.8 EMC94962.1 - 0.85 10.5 3.1 2.3 9.1 3.1 1.7 1 0 0 1 1 1 0 T-box transcription factor TPR_1 PF00515.28 EMC94962.1 - 2.5 8.1 4.6 9.6 6.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat LSM PF01423.22 EMC94963.1 - 8.4e-15 54.2 0.2 1.3e-14 53.7 0.2 1.3 1 0 0 1 1 1 1 LSM domain HbrB PF08539.11 EMC94966.1 - 1.6e-54 184.4 0.0 3e-54 183.5 0.0 1.5 1 0 0 1 1 1 1 HbrB-like Pkinase PF00069.25 EMC94968.1 - 3.2e-67 226.7 0.0 4.5e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC94968.1 - 3.6e-35 121.5 0.1 7.5e-35 120.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC94968.1 - 1.6e-06 27.6 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMC94968.1 - 0.0026 17.2 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EMC94968.1 - 0.0028 17.2 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 EMC94968.1 - 0.093 12.3 0.1 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EMC94968.1 - 0.2 11.5 1.5 0.9 9.4 0.3 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family UQ_con PF00179.26 EMC94969.1 - 3.2e-25 88.4 0.1 3.7e-25 88.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMC94969.1 - 5.5e-05 22.9 0.0 6.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMC94969.1 - 0.24 11.7 1.2 0.96 9.8 0.8 1.9 1 1 0 2 2 2 0 RWD domain DUF3328 PF11807.8 EMC94970.1 - 2.2e-10 40.7 6.2 2.2e-10 40.7 6.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Ank_2 PF12796.7 EMC94971.1 - 1.4e-33 115.3 1.3 8e-11 42.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC94971.1 - 4.5e-26 90.9 2.8 9.1e-06 26.1 0.1 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC94971.1 - 9.1e-25 84.0 0.6 0.00064 20.0 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EMC94971.1 - 2.2e-23 81.6 9.6 0.00034 20.9 0.2 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EMC94971.1 - 3e-19 68.8 7.7 0.00021 21.5 0.3 5.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) FA PF08736.11 EMC94971.1 - 0.00053 20.0 0.2 0.29 11.2 0.0 3.1 3 0 0 3 3 3 1 FERM adjacent (FA) Sec1 PF00995.23 EMC94972.1 - 3.2e-86 290.8 0.1 3.6e-86 290.6 0.1 1.0 1 0 0 1 1 1 1 Sec1 family RNA_pol_Rpb2_4 PF04566.13 EMC94972.1 - 0.093 13.0 0.3 17 5.8 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 Thioredoxin_13 PF18401.1 EMC94972.1 - 0.24 11.3 2.3 8.7 6.3 0.7 2.8 2 1 0 2 2 2 0 Thioredoxin-like domain Myosin_head PF00063.21 EMC94973.1 - 7e-244 811.1 7.6 8.3e-244 810.8 7.6 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EMC94973.1 - 8.6e-52 175.5 0.0 1.5e-51 174.7 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EMC94973.1 - 1.7e-12 46.7 0.1 3.4e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMC94973.1 - 1.7e-10 40.6 0.1 3.9e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMC94973.1 - 3.9e-08 32.8 0.0 1.2e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EMC94973.1 - 0.0085 16.4 0.1 0.022 15.1 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_16 PF13191.6 EMC94973.1 - 0.02 15.3 0.0 0.067 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain IQ PF00612.27 EMC94973.1 - 0.033 14.0 8.2 1.8 8.6 2.1 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 EMC94973.1 - 0.057 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EMC94973.1 - 0.1 12.1 1.7 6.7 6.2 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_19 PF13245.6 EMC94973.1 - 0.11 12.8 0.0 2.3 8.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EMC94973.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EMC94973.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain GFA PF04828.14 EMC94974.1 - 6.4e-18 64.9 0.2 8.7e-18 64.5 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 EMC94974.1 - 0.49 10.1 6.3 1.1 9.0 0.2 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PX PF00787.24 EMC94976.1 - 2.6e-18 66.1 0.0 3.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 PX domain TcdA_TcdB_pore PF12920.7 EMC94976.1 - 0.09 11.0 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain tRNA-synt_His PF13393.6 EMC94977.1 - 7.2e-37 127.3 0.0 1.2e-35 123.3 0.0 2.3 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EMC94977.1 - 2.2e-11 43.7 0.0 8.1e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EMC94977.1 - 1.7e-05 24.5 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 EMC94977.1 - 0.0033 17.4 0.0 0.0052 16.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EMC94977.1 - 0.0038 16.4 0.0 0.016 14.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF3433 PF11915.8 EMC94978.1 - 5.4e-24 84.5 14.5 2e-14 53.8 5.3 4.6 6 0 0 6 6 6 2 Protein of unknown function (DUF3433) adh_short PF00106.25 EMC94979.1 - 2.6e-44 151.0 1.6 4.1e-44 150.4 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC94979.1 - 2.9e-41 141.6 0.6 1.2e-40 139.5 0.6 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC94979.1 - 2.9e-10 40.4 0.3 6.2e-10 39.3 0.3 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMC94979.1 - 5.3e-05 22.7 0.4 8.1e-05 22.1 0.1 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EMC94979.1 - 0.0014 17.8 0.1 0.0023 17.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EMC94979.1 - 0.0074 16.4 0.2 0.019 15.0 0.2 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EMC94979.1 - 0.018 14.5 0.2 0.055 12.9 0.2 1.8 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Dak1 PF02733.17 EMC94979.1 - 0.019 13.9 0.3 0.4 9.5 0.0 2.2 2 0 0 2 2 2 0 Dak1 domain ADH_zinc_N PF00107.26 EMC94979.1 - 0.037 14.0 0.1 0.062 13.3 0.1 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.27 EMC94979.1 - 0.073 13.6 0.3 0.67 10.5 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC94980.1 - 7.9e-25 87.8 0.0 4.1e-12 46.0 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EMC94980.1 - 2.6e-06 26.7 0.3 0.00062 18.9 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein SE PF08491.10 EMC94980.1 - 0.00018 20.7 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 EMC94980.1 - 0.00037 20.2 0.8 0.0035 17.0 0.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC94980.1 - 0.00067 19.8 0.1 0.0022 18.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC94980.1 - 0.00074 18.8 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC94980.1 - 0.0015 17.5 0.0 0.0048 15.8 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 EMC94980.1 - 0.013 14.2 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 EMC94980.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMC94980.1 - 0.026 14.5 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMC94980.1 - 0.047 14.2 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC94980.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EMC94980.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4336 PF14234.6 EMC94981.1 - 1.2e-16 60.8 0.0 6.9e-11 41.9 0.0 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4336) DUF2780 PF11075.8 EMC94982.1 - 0.027 14.6 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) Thioesterase PF00975.20 EMC94983.1 - 1.8e-22 80.6 0.0 3.5e-22 79.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EMC94983.1 - 9.6e-05 22.7 0.0 0.00017 21.9 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 EMC94983.1 - 0.012 16.3 0.0 0.03 14.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pyr_redox PF00070.27 EMC94983.1 - 0.13 12.9 0.1 0.41 11.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2974 PF11187.8 EMC94983.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EMC94983.1 - 0.18 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold SNase PF00565.17 EMC94984.1 - 4.8e-24 84.9 0.2 8.2e-24 84.2 0.2 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Topoisom_I PF01028.20 EMC94985.1 - 1.3e-96 322.3 2.2 3.5e-96 320.9 2.2 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EMC94985.1 - 8.8e-96 319.5 7.2 8.8e-96 319.5 7.2 3.6 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EMC94985.1 - 1.2e-31 108.4 0.3 4.9e-31 106.5 0.3 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.19 EMC94986.1 - 6.9e-80 268.7 2.1 8.4e-80 268.5 2.1 1.0 1 0 0 1 1 1 1 ATP synthase Fungal_trans PF04082.18 EMC94987.1 - 8.3e-11 41.4 0.3 1.5e-10 40.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC94987.1 - 1.2e-07 31.8 11.1 2.2e-07 30.9 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 EMC94987.1 - 0.0067 16.5 1.0 0.026 14.6 1.0 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 PHD PF00628.29 EMC94988.1 - 2.4e-05 24.1 5.7 3.6e-05 23.5 5.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-piccolo PF05715.13 EMC94988.1 - 0.22 11.7 3.5 0.51 10.5 3.5 1.6 1 1 0 1 1 1 0 Piccolo Zn-finger PHD_4 PF16866.5 EMC94988.1 - 0.5 10.5 5.5 0.81 9.8 5.5 1.3 1 0 0 1 1 1 0 PHD-finger Abhydrolase_1 PF00561.20 EMC94989.1 - 4.8e-15 55.9 0.0 2e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC94989.1 - 1.1e-14 54.3 0.0 1.8e-08 34.0 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMC94989.1 - 2.6e-11 44.6 0.0 3.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EMC94989.1 - 0.064 13.0 0.1 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 EMC94989.1 - 0.068 12.0 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EMC94989.1 - 0.11 11.9 0.0 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 EMC94989.1 - 0.12 12.2 0.0 2.7 7.9 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cu-oxidase_3 PF07732.15 EMC94990.1 - 1.2e-36 125.3 0.4 1.2e-36 125.3 0.4 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EMC94990.1 - 6.5e-31 107.6 0.6 2.8e-29 102.3 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMC94990.1 - 8e-31 106.6 2.6 8e-31 106.6 2.6 3.6 4 0 0 4 4 4 2 Multicopper oxidase ERO1 PF04137.15 EMC94993.1 - 2.1e-134 448.2 0.0 2.5e-134 447.9 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF423 PF04241.15 EMC94994.1 - 3.6e-26 91.2 0.4 4.9e-26 90.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Vps8 PF12816.7 EMC94995.1 - 5.1e-67 225.2 0.0 1e-66 224.2 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EMC94995.1 - 4.6e-07 29.8 0.0 0.047 13.6 0.0 3.4 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.6 EMC94995.1 - 3.7e-05 24.0 0.3 0.0001 22.6 0.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EMC94995.1 - 0.002 18.4 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EMC94995.1 - 0.0094 15.9 0.1 0.0094 15.9 0.1 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EMC94995.1 - 0.01 15.7 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC94995.1 - 0.036 13.9 0.2 0.079 12.8 0.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EMC94995.1 - 0.11 12.4 5.0 0.024 14.5 0.9 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EMC94995.1 - 0.33 11.0 3.4 0.29 11.2 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger zf-RING_11 PF17123.5 EMC94995.1 - 0.36 10.6 2.3 0.29 10.9 0.2 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EMC94995.1 - 0.42 10.7 2.0 0.84 9.7 0.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger PHD PF00628.29 EMC94995.1 - 0.47 10.4 3.0 0.22 11.5 0.2 1.9 2 0 0 2 2 2 0 PHD-finger DUF3752 PF12572.8 EMC94996.1 - 2e-40 138.8 14.7 2e-40 138.8 14.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) RCR PF12273.8 EMC94997.1 - 8.5e-12 45.8 4.7 2.1e-11 44.5 4.7 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red FeS_assembly_P PF01883.19 EMC94998.1 - 2.9e-10 40.1 0.0 9.4e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Fungal_trans PF04082.18 EMC94999.1 - 5.6e-07 28.9 0.2 1.3e-06 27.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC94999.1 - 9.8e-07 28.8 7.2 9.8e-07 28.8 7.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EMC95000.1 - 3.1e-33 115.2 27.3 4.1e-33 114.8 27.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMC95000.1 - 1.8e-06 27.5 2.1 1.8e-06 27.5 2.1 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB 7tm_2 PF00002.24 EMC95002.1 - 5.3e-07 29.2 10.2 2.7e-06 26.9 10.2 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3675 PF12428.8 EMC95002.1 - 0.25 11.9 0.2 0.25 11.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Vut_1 PF02592.15 EMC95002.1 - 1.5 9.1 11.8 0.13 12.6 1.3 2.9 3 0 0 3 3 3 0 Putative vitamin uptake transporter SURNod19 PF07712.12 EMC95003.1 - 0.0047 15.7 0.0 0.0065 15.3 0.0 1.2 1 0 0 1 1 1 1 Stress up-regulated Nod 19 DUF1708 PF08101.11 EMC95004.1 - 2.9e-164 547.3 0.0 4.1e-164 546.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Thioredoxin PF00085.20 EMC95005.1 - 1.8e-32 111.4 0.0 4.9e-26 90.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EMC95005.1 - 3.4e-06 27.5 0.1 0.095 13.2 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EMC95005.1 - 1.9e-05 24.2 0.0 0.0007 19.0 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 EMC95005.1 - 0.0005 20.0 7.7 0.015 15.2 0.0 3.3 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 EMC95005.1 - 0.0027 18.0 0.0 3.2 8.1 0.0 3.3 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 EMC95005.1 - 0.0054 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family ERp29_N PF07912.13 EMC95005.1 - 0.023 14.8 0.0 0.068 13.3 0.0 1.7 2 0 0 2 2 2 0 ERp29, N-terminal domain SAPS PF04499.15 EMC95005.1 - 0.16 10.7 0.8 0.26 10.0 0.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vta1 PF04652.16 EMC95006.1 - 4.6e-54 182.3 5.1 5.3e-54 182.1 3.2 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EMC95006.1 - 7.6e-14 51.1 0.0 1.6e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain Sec6 PF06046.13 EMC95008.1 - 6.4e-140 467.3 0.0 8.5e-140 466.8 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Cas_APE2256 PF09651.10 EMC95008.1 - 0.018 14.9 0.8 0.16 11.8 0.0 2.9 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_APE2256) Vps53_N PF04100.12 EMC95008.1 - 0.17 10.8 1.3 0.48 9.3 0.3 2.2 3 0 0 3 3 3 0 Vps53-like, N-terminal Ribosomal_L30 PF00327.20 EMC95009.1 - 4.5e-12 45.6 0.0 6.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Clat_adaptor_s PF01217.20 EMC95011.1 - 4.5e-43 146.6 0.1 4.4e-42 143.4 0.1 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain OSCP PF00213.18 EMC95016.1 - 3.9e-43 147.6 0.7 4.7e-43 147.3 0.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Pox_A51 PF04948.13 EMC95016.1 - 0.0061 15.5 0.0 0.0085 15.0 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A51 protein TFIIE_beta PF02186.15 EMC95016.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 TFIIE beta subunit core domain HNH PF01844.23 EMC95017.1 - 0.041 14.1 0.2 0.076 13.2 0.2 1.5 1 0 0 1 1 1 0 HNH endonuclease Pectate_lyase_3 PF12708.7 EMC95018.1 - 3.2e-83 278.8 5.4 3.1e-77 259.3 3.1 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EMC95018.1 - 0.00025 20.7 4.2 0.028 14.1 0.4 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase DUF3671 PF12420.8 EMC95018.1 - 0.023 14.8 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function Beta_helix PF13229.6 EMC95018.1 - 0.26 11.1 18.1 0.069 13.0 5.9 3.6 3 1 0 3 3 3 0 Right handed beta helix region IMS PF00817.20 EMC95019.1 - 4.2e-36 124.2 0.0 7.3e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EMC95019.1 - 3e-14 53.7 0.2 1.8e-13 51.2 0.1 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EMC95019.1 - 0.0052 17.1 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH_8 PF14716.6 EMC95019.1 - 0.13 12.7 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ribosomal_L16 PF00252.18 EMC95021.1 - 4.6e-31 107.6 0.0 5.9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 EMC95022.1 - 1.2e-55 187.9 0.0 2.8e-55 186.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EMC95022.1 - 5.7e-15 55.5 0.0 1.6e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EMC95022.1 - 1.3e-09 38.6 0.1 4.1e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EMC95022.1 - 8e-06 25.9 0.0 2.8e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EMC95022.1 - 0.00011 22.5 0.0 0.00033 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC95022.1 - 0.00065 20.1 0.1 0.0085 16.5 0.1 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EMC95022.1 - 0.0007 19.8 0.2 0.0023 18.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EMC95022.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EMC95022.1 - 0.006 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EMC95022.1 - 0.014 15.1 0.1 0.075 12.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMC95022.1 - 0.017 15.7 0.3 0.079 13.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMC95022.1 - 0.032 14.5 0.6 0.22 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EMC95022.1 - 0.044 13.7 0.2 0.65 9.9 0.0 2.5 3 0 0 3 3 2 0 NACHT domain PTCB-BRCT PF12738.7 EMC95022.1 - 0.067 13.1 0.0 0.22 11.5 0.0 2.0 1 0 0 1 1 1 0 twin BRCT domain NTPase_1 PF03266.15 EMC95022.1 - 0.082 12.8 0.1 0.53 10.2 0.0 2.3 3 0 0 3 3 3 0 NTPase DNA_pol3_delta PF06144.13 EMC95022.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.22 EMC95022.1 - 0.2 12.0 0.3 0.67 10.4 0.0 2.1 2 0 0 2 2 1 0 RNA helicase Rrn6 PF10214.9 EMC95022.1 - 0.3 9.5 1.3 0.46 8.9 1.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AAA_17 PF13207.6 EMC95022.1 - 1.2 9.6 7.3 1.7 9.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 EMC95022.1 - 5.1 7.3 8.2 1.8 8.8 0.1 3.0 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain SPT6_acidic PF14632.6 EMC95022.1 - 6.8 7.4 15.0 0.28 11.8 8.5 2.0 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Plasmodium_Vir PF05795.11 EMC95024.1 - 0.38 10.1 4.2 0.49 9.8 4.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PTH2 PF01981.16 EMC95026.1 - 7.3e-46 155.3 0.9 9.6e-46 154.9 0.9 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Sulfatase PF00884.23 EMC95028.1 - 1.3e-51 175.8 0.0 2e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EMC95028.1 - 9.7e-25 86.1 2.6 2.1e-24 85.1 2.6 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EMC95028.1 - 6.8e-10 39.1 0.1 1.2e-08 35.0 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EMC95028.1 - 0.0023 18.6 0.2 0.011 16.5 0.2 2.1 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 EMC95028.1 - 0.01 14.4 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4976 PF16347.5 EMC95028.1 - 0.031 14.6 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) PRO8NT PF08082.11 EMC95028.1 - 0.076 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Adeno_100 PF02438.16 EMC95028.1 - 0.19 9.9 0.0 0.32 9.1 0.0 1.3 1 0 0 1 1 1 0 Late 100kD protein PIR PF00399.19 EMC95029.1 - 1.3e-48 161.5 69.8 2.4e-08 33.3 1.2 7.4 7 0 0 7 7 7 6 Yeast PIR protein repeat B1 PF02246.15 EMC95029.1 - 0.13 12.3 0.1 0.46 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein L b1 domain Gon7 PF08738.10 EMC95030.1 - 1.3e-11 44.6 1.3 1.3e-11 44.6 1.3 1.6 1 1 1 2 2 2 1 Gon7 family DUF4611 PF15387.6 EMC95030.1 - 0.081 13.1 2.2 0.11 12.7 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) ADH_zinc_N PF00107.26 EMC95031.1 - 4.6e-11 42.8 0.0 9.6e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC95031.1 - 0.0007 19.5 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EMC95031.1 - 0.0021 17.6 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EMC95031.1 - 0.0076 17.3 0.0 0.014 16.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DNA_pol3_delta2 PF13177.6 EMC95032.1 - 2.4e-11 43.7 0.0 5.1e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EMC95032.1 - 3.5e-06 27.5 0.1 7.9e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EMC95032.1 - 2.9e-05 24.4 0.4 8.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 EMC95032.1 - 0.00028 21.2 0.3 0.0017 18.7 0.2 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMC95032.1 - 0.0018 18.7 1.4 0.028 14.8 0.8 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EMC95032.1 - 0.0023 17.7 0.5 0.0081 15.9 0.5 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMC95032.1 - 0.0049 17.4 0.0 0.012 16.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 EMC95032.1 - 0.019 15.5 0.0 0.028 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMC95032.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 EMC95032.1 - 0.055 13.2 0.1 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EMC95032.1 - 0.086 12.2 0.0 0.28 10.6 0.0 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMC95032.1 - 0.14 12.1 0.2 0.36 10.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2543 PF10820.8 EMC95033.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) HAD_2 PF13419.6 EMC95034.1 - 5e-06 26.7 0.0 7.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMC95034.1 - 0.00097 19.5 0.0 0.0015 18.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EMC95034.1 - 0.0018 18.4 0.0 0.086 13.0 0.0 2.6 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase C2 PF00168.30 EMC95035.1 - 1.2e-28 99.3 0.2 5.2e-17 62.0 0.0 2.9 3 0 0 3 3 3 2 C2 domain Amidohydro_1 PF01979.20 EMC95036.1 - 8.2e-09 35.2 0.5 1.7e-08 34.2 0.1 1.8 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMC95036.1 - 2.6e-08 33.8 0.2 2.8e-07 30.4 0.0 2.4 3 0 0 3 3 3 1 Amidohydrolase family WD40 PF00400.32 EMC95037.1 - 1.9e-17 63.3 12.2 0.025 15.4 0.1 9.3 9 0 0 9 9 9 5 WD domain, G-beta repeat HPS3_N PF14761.6 EMC95037.1 - 0.054 13.0 0.1 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 AMP-binding PF00501.28 EMC95038.1 - 2e-90 303.4 0.2 2.4e-90 303.1 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC95038.1 - 4.7e-26 91.6 0.4 1.2e-24 87.1 0.2 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EMC95038.1 - 3.1e-14 52.6 0.1 7e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus EnY2 PF10163.9 EMC95039.1 - 8.9e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 MFS_1 PF07690.16 EMC95040.1 - 2.1e-21 76.3 59.8 3.2e-19 69.1 42.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 EMC95040.1 - 0.0019 16.9 5.6 0.0019 16.9 5.6 2.3 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like UvdE PF03851.14 EMC95041.1 - 2.1e-112 374.9 0.0 2.9e-112 374.4 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DOCK_N PF16172.5 EMC95042.1 - 1.9e-103 346.3 0.5 3.1e-103 345.6 0.5 1.4 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 EMC95042.1 - 8.5e-41 140.2 4.5 6.9e-40 137.2 4.5 2.0 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EMC95042.1 - 1.3e-31 109.9 0.0 5e-31 108.0 0.0 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 EMC95042.1 - 8.7e-09 35.1 0.7 1.2e-06 28.3 0.0 3.3 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 EMC95042.1 - 1.4e-06 27.8 0.0 3.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMC95042.1 - 7.1e-05 22.4 0.0 0.00016 21.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ig_mannosidase PF17753.1 EMC95043.1 - 2.7e-21 75.1 0.5 2.7e-21 75.1 0.5 2.0 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 EMC95043.1 - 1.6e-08 35.1 1.7 1.2e-07 32.3 0.1 2.8 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EMC95043.1 - 1.7e-07 31.9 0.0 2e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 N6-adenineMlase PF10237.9 EMC95043.1 - 0.12 12.1 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase AA_permease_2 PF13520.6 EMC95044.1 - 9.5e-66 222.4 40.8 1.2e-65 222.0 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC95044.1 - 5.9e-19 68.0 34.7 7.3e-19 67.7 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease Metallophos PF00149.28 EMC95045.1 - 2.9e-10 41.0 0.1 4e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMC95045.1 - 7.2e-08 32.8 0.0 6.7e-05 23.1 0.1 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 EMC95045.1 - 0.048 13.2 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain AKAP7_NLS PF10469.9 EMC95047.1 - 1.9e-19 70.4 0.0 3.5e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain RPA_interact_N PF14766.6 EMC95047.1 - 0.68 9.6 2.3 1.4 8.6 2.3 1.5 1 0 0 1 1 1 0 Replication protein A interacting N-terminal GET2 PF08690.10 EMC95048.1 - 5e-25 88.8 0.0 8.2e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 GET complex subunit GET2 DUF4233 PF14017.6 EMC95048.1 - 0.41 11.0 5.9 0.25 11.7 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Ribosomal_L28 PF00830.19 EMC95049.1 - 3.3e-17 62.4 0.9 4.9e-17 61.9 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L28 family L51_S25_CI-B8 PF05047.16 EMC95050.1 - 4.2e-13 49.0 0.0 6.9e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ubiquitin_3 PF14836.6 EMC95051.1 - 0.04 13.9 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain AAA_22 PF13401.6 EMC95052.1 - 1.3e-07 31.9 0.0 5.5e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMC95052.1 - 2e-07 31.1 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMC95052.1 - 5e-05 23.8 0.0 0.00038 20.9 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 EMC95052.1 - 0.00086 18.7 0.2 0.0015 17.9 0.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TFIIE_beta PF02186.15 EMC95052.1 - 0.019 15.2 0.1 1.4 9.2 0.1 3.1 2 0 0 2 2 2 0 TFIIE beta subunit core domain DUF2075 PF09848.9 EMC95052.1 - 0.021 14.1 0.0 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EMC95052.1 - 0.027 14.9 0.4 0.26 11.7 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EMC95052.1 - 0.028 13.7 0.1 3 7.0 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.6 EMC95052.1 - 0.029 14.5 0.3 0.19 11.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain SesA PF17107.5 EMC95052.1 - 0.091 12.9 0.1 0.34 11.1 0.0 2.0 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ATPase_2 PF01637.18 EMC95052.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Adeno_E3B PF03376.14 EMC95052.1 - 0.33 11.2 1.2 2.9 8.2 0.1 2.3 2 0 0 2 2 2 0 Adenovirus E3B protein Fringe PF02434.16 EMC95053.1 - 1.8e-05 24.3 0.1 0.00049 19.6 0.0 2.4 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 EMC95053.1 - 0.067 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 PAN domain Mod_r PF07200.13 EMC95054.1 - 0.003 17.7 0.4 0.0034 17.5 0.4 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RIC3 PF15361.6 EMC95054.1 - 0.0097 16.3 1.7 0.0097 16.3 1.7 1.9 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 SlyX PF04102.12 EMC95054.1 - 0.011 16.3 0.5 0.011 16.3 0.5 1.7 2 0 0 2 2 2 0 SlyX Csm1_N PF18504.1 EMC95054.1 - 0.52 10.7 4.8 0.9 9.9 4.8 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain M PF02370.16 EMC95054.1 - 2.3 9.1 7.7 17 6.4 1.3 2.6 1 1 1 2 2 2 0 M protein repeat HrpB7 PF09486.10 EMC95054.1 - 3.7 7.9 10.7 0.13 12.7 2.0 2.0 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GAIN_A PF18619.1 EMC95054.1 - 8.5 6.7 7.6 0.35 11.1 0.6 2.3 3 0 0 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A PRTase_2 PF15609.6 EMC95055.1 - 0.056 12.9 0.1 0.064 12.8 0.1 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase Bromodomain PF00439.25 EMC95056.1 - 6e-08 32.6 0.0 4.7e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Bromodomain NuA4 PF09340.10 EMC95057.1 - 1e-26 92.6 0.0 2e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Lactamase_B PF00753.27 EMC95058.1 - 0.0011 19.0 0.2 0.0018 18.3 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ADK_lid PF05191.14 EMC95058.1 - 0.14 12.2 0.8 0.31 11.1 0.8 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid FAD_binding_2 PF00890.24 EMC95060.1 - 5.5e-81 272.8 0.1 7.6e-81 272.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EMC95060.1 - 5.7e-21 74.4 0.5 1.1e-18 67.2 0.0 3.4 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EMC95060.1 - 8.9e-13 48.5 0.1 2.2e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EMC95060.1 - 9e-10 38.5 0.8 3.7e-09 36.5 0.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC95060.1 - 1.3e-07 31.7 0.6 7.7e-07 29.3 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC95060.1 - 2.2e-07 30.4 1.0 7.3e-07 28.7 0.4 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC95060.1 - 1.3e-06 27.9 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC95060.1 - 4e-05 22.5 7.3 5.5e-05 22.1 1.5 2.8 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EMC95060.1 - 6.8e-05 22.1 1.0 0.016 14.3 0.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EMC95060.1 - 0.00016 21.0 0.1 0.022 14.0 0.1 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EMC95060.1 - 0.0036 16.6 0.5 0.0067 15.7 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EMC95060.1 - 0.0049 17.4 1.8 1.8 9.2 0.3 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMC95060.1 - 0.0062 15.9 0.2 0.011 15.0 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EMC95060.1 - 0.0089 16.0 0.5 0.13 12.2 0.5 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EMC95060.1 - 0.022 14.1 0.6 1.4 8.2 0.0 3.1 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 EMC95060.1 - 0.029 14.2 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EMC95060.1 - 0.081 12.6 0.2 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Secretin_N_2 PF07655.13 EMC95062.1 - 0.02 15.5 0.2 0.039 14.5 0.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Aminotran_3 PF00202.21 EMC95063.1 - 3.3e-115 385.0 0.0 4.2e-115 384.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMC95063.1 - 0.0003 20.1 0.0 0.00048 19.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_3_C PF01915.22 EMC95065.1 - 4.5e-39 134.5 0.1 7.8e-39 133.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMC95065.1 - 2.5e-26 92.8 0.0 3.9e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Ribosomal_S8e PF01201.22 EMC95067.1 - 1.3e-53 180.8 2.3 1.5e-53 180.6 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e S10_plectin PF03501.15 EMC95068.1 - 4.9e-42 141.9 0.2 6e-42 141.6 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.28 EMC95069.1 - 9.7e-29 100.5 0.0 1.5e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMC95069.1 - 5.7e-06 26.2 0.0 2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMC95069.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Sugar_tr PF00083.24 EMC95070.1 - 3.5e-77 260.2 29.3 4e-77 260.0 29.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC95070.1 - 3.2e-21 75.7 28.4 3.2e-21 75.7 28.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EMC95070.1 - 0.0067 14.8 9.2 0.0028 16.0 6.1 1.9 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family SPX PF03105.19 EMC95071.1 - 5.1e-41 141.9 2.0 5.7e-27 95.6 0.3 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 EMC95071.1 - 1.3e-28 100.3 41.1 1.8e-28 99.8 41.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EMC95071.1 - 8.3e-25 87.6 49.5 4e-19 68.9 18.2 2.3 1 1 1 2 2 2 2 Citrate transporter DUF3043 PF11241.8 EMC95071.1 - 0.053 13.6 2.1 0.17 11.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) Ldh_2 PF02615.14 EMC95072.1 - 3.5e-128 427.4 0.9 4e-128 427.3 0.9 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase zf-CSL PF05207.13 EMC95073.1 - 1.4e-21 76.0 1.6 1.9e-21 75.6 1.6 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 EMC95073.1 - 0.00089 19.3 0.9 0.0015 18.6 0.9 1.5 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 EMC95073.1 - 0.0046 15.6 0.2 0.0055 15.3 0.2 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Zn_ribbon_SprT PF17283.2 EMC95073.1 - 0.075 13.0 0.2 10 6.1 0.0 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Frataxin_Cyay PF01491.16 EMC95074.1 - 1.3e-36 125.0 0.0 1.6e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain OPA3 PF07047.12 EMC95075.1 - 2.5e-46 156.5 2.4 4e-46 155.9 2.4 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Herpes_UL25 PF01499.16 EMC95075.1 - 0.19 10.2 4.7 0.34 9.4 0.3 2.2 2 0 0 2 2 2 0 Herpesvirus UL25 family Connexin PF00029.19 EMC95075.1 - 0.62 9.8 1.4 1.1 9.0 1.4 1.4 1 0 0 1 1 1 0 Connexin CCDC53 PF10152.9 EMC95075.1 - 3.4 8.1 8.6 0.77 10.2 0.6 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RNA_pol_Rpc4 PF05132.14 EMC95075.1 - 3.6 8.0 9.1 0.27 11.7 1.1 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 U79_P34 PF03064.16 EMC95075.1 - 6 6.1 10.3 13 5.1 10.3 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Vfa1 PF08432.10 EMC95075.1 - 7.8 6.8 14.4 0.61 10.4 5.1 2.5 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RRM_1 PF00076.22 EMC95077.1 - 5.9e-12 45.2 1.2 2e-11 43.5 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMC95077.1 - 0.084 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF374 PF04028.13 EMC95077.1 - 0.093 12.3 0.1 0.29 10.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF374) RRM_3 PF08777.11 EMC95077.1 - 0.27 11.3 1.1 0.8 9.8 0.1 2.1 2 0 0 2 2 2 0 RNA binding motif Glyco_hydro_16 PF00722.21 EMC95079.1 - 5.6e-06 25.9 0.0 1.9e-05 24.2 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 GFA PF04828.14 EMC95080.1 - 4.1e-14 52.7 0.0 6.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Helicase_C PF00271.31 EMC95081.1 - 5.3e-20 71.8 0.0 1.4e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC95081.1 - 2.5e-19 69.9 0.0 4.6e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMC95081.1 - 1.7e-14 54.0 0.0 2.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EMC95081.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase KH_1 PF00013.29 EMC95082.1 - 4.9e-45 151.2 10.8 1.2e-15 57.0 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EMC95082.1 - 2.2e-13 49.8 4.5 0.0014 18.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EMC95082.1 - 1.5e-09 37.5 4.2 0.026 14.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EMC95082.1 - 0.00026 21.0 6.2 0.22 11.6 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 EMC95082.1 - 0.0082 16.1 0.1 1.6 8.8 0.0 2.8 3 0 0 3 3 3 1 KH-like RNA-binding domain GRP PF07172.11 EMC95082.1 - 0.079 13.7 12.6 1.8 9.3 3.2 2.6 2 0 0 2 2 2 0 Glycine rich protein family K_channel_TID PF07941.11 EMC95082.1 - 1.1 9.8 10.8 4.5 7.8 3.5 3.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain GCN5L1 PF06320.13 EMC95083.1 - 9.6e-17 61.2 1.1 1.1e-16 61.0 1.1 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) OmpH PF03938.14 EMC95083.1 - 0.045 14.1 1.6 0.063 13.6 1.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 EMC95083.1 - 0.087 11.5 1.2 0.099 11.3 1.2 1.0 1 0 0 1 1 1 0 AAA domain Ald_Xan_dh_C2 PF02738.18 EMC95084.1 - 7.7e-209 694.7 1.3 1.1e-208 694.2 1.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EMC95084.1 - 2.4e-48 164.1 0.0 5.9e-48 162.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EMC95084.1 - 1.3e-32 112.0 0.0 3.8e-32 110.5 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EMC95084.1 - 2.8e-31 108.1 0.0 6.6e-31 106.9 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EMC95084.1 - 4.2e-30 103.6 0.1 9.6e-30 102.4 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EMC95084.1 - 9.6e-08 31.9 0.2 9.6e-08 31.9 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SKN1 PF03935.15 EMC95086.1 - 1.6e-213 709.7 0.2 1.9e-213 709.5 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Diphthamide_syn PF01866.17 EMC95087.1 - 1e-113 379.8 0.0 1.2e-113 379.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Arginase PF00491.21 EMC95089.1 - 3.4e-91 305.6 0.0 4.4e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EMC95089.1 - 0.039 14.2 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.18 EMC95090.1 - 1.1e-57 194.1 19.8 4.7e-30 104.4 6.4 2.4 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EMC95090.1 - 3e-08 33.8 7.7 3e-08 33.8 7.7 3.9 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain CD225 PF04505.12 EMC95090.1 - 0.087 13.0 2.3 0.1 12.7 0.4 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein AA_permease_2 PF13520.6 EMC95091.1 - 1.2e-42 146.2 51.2 1.6e-42 145.8 51.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC95091.1 - 4e-20 71.9 41.1 5.5e-20 71.4 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 EMC95092.1 - 1.4e-17 63.6 33.8 9.4e-09 34.6 19.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily SHP PF03579.13 EMC95092.1 - 0.46 10.5 3.0 1.7 8.7 3.0 2.0 1 0 0 1 1 1 0 Small hydrophobic protein OATP PF03137.20 EMC95092.1 - 1.3 7.3 8.7 0.046 12.0 0.5 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SART-1 PF03343.13 EMC95093.1 - 8.1e-167 556.5 68.0 1.1e-166 556.2 68.0 1.1 1 0 0 1 1 1 1 SART-1 family SspO PF08175.12 EMC95093.1 - 2.6 8.6 7.6 1 9.9 1.8 3.3 2 0 0 2 2 2 0 Small acid-soluble spore protein O family MRG PF05712.13 EMC95094.1 - 5.4e-51 172.7 0.7 8e-51 172.2 0.7 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EMC95094.1 - 1.4e-08 34.5 1.7 2.8e-08 33.5 1.7 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 EMC95094.1 - 0.076 13.4 0.2 0.24 11.8 0.1 1.8 2 0 0 2 2 2 0 PWWP domain Chromo PF00385.24 EMC95094.1 - 0.14 12.1 1.4 0.31 11.0 1.4 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain His_Phos_1 PF00300.22 EMC95096.1 - 8.3e-28 97.4 0.0 1.9e-27 96.2 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2-Hacid_dh_C PF02826.19 EMC95097.1 - 4.2e-40 137.0 0.0 5.4e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMC95097.1 - 5.3e-19 68.2 0.0 6.2e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMC95097.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NTP_transf_3 PF12804.7 EMC95097.1 - 0.013 15.9 0.1 0.09 13.1 0.0 2.1 2 0 0 2 2 2 0 MobA-like NTP transferase domain adh_short PF00106.25 EMC95098.1 - 8.7e-54 181.9 3.0 1.3e-53 181.4 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC95098.1 - 1.2e-36 126.5 2.1 1.5e-36 126.1 2.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC95098.1 - 1e-11 45.1 1.5 1.7e-11 44.4 0.9 1.6 2 0 0 2 2 2 1 KR domain DUF881 PF05949.12 EMC95098.1 - 0.034 14.0 0.4 0.059 13.2 0.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) HEM4 PF02602.15 EMC95098.1 - 0.034 13.5 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD DUF2335 PF10097.9 EMC95098.1 - 0.19 11.7 0.5 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) B12D PF06522.11 EMC95099.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Pyridoxal_deC PF00282.19 EMC95100.1 - 5.8e-19 68.1 0.0 8e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EMC95100.1 - 7.8e-05 21.8 0.0 0.00014 20.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMC95100.1 - 0.0039 16.6 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1775 PF07987.11 EMC95100.1 - 0.0044 17.3 0.0 0.0085 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) Mto2_bdg PF12808.7 EMC95100.1 - 0.068 13.5 1.5 0.088 13.1 0.1 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SRA1 PF07304.11 EMC95102.1 - 1.4e-07 31.4 0.0 1.4e-07 31.4 0.0 3.7 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) ANAPC4_WD40 PF12894.7 EMC95102.1 - 5.6e-06 26.6 0.3 0.0065 16.7 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMC95102.1 - 3.6e-05 24.4 1.3 5.4 8.1 0.0 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Prp18 PF02840.15 EMC95102.1 - 0.016 15.3 1.0 0.063 13.3 0.0 2.3 2 1 0 2 2 2 0 Prp18 domain DUF4455 PF14643.6 EMC95102.1 - 0.017 13.8 0.1 0.033 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Sec16_C PF12931.7 EMC95102.1 - 0.049 13.3 2.0 0.28 10.8 2.0 2.0 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 RRM_1 PF00076.22 EMC95103.1 - 7.6e-17 60.9 0.0 1e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC95103.1 - 0.0062 16.6 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EMC95103.1 - 0.034 14.2 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 Fungal_trans_2 PF11951.8 EMC95104.1 - 9.6e-52 176.1 0.4 1.7e-51 175.3 0.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC95104.1 - 2.5e-06 27.5 7.4 4.9e-06 26.6 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EMC95106.1 - 2.7e-10 40.0 0.0 3.7e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC95106.1 - 5.6e-10 39.2 0.2 1.2e-09 38.1 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.13 EMC95106.1 - 0.015 15.3 0.0 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family GMC_oxred_N PF00732.19 EMC95107.1 - 2.2e-58 198.0 0.0 4.7e-58 196.9 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC95107.1 - 1.2e-34 119.9 0.0 2.1e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMC95107.1 - 9.1e-06 25.0 0.0 2.3e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EMC95107.1 - 4.2e-05 23.3 0.0 0.00053 19.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMC95107.1 - 0.0016 17.6 0.0 0.012 14.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EMC95107.1 - 0.0021 18.2 0.0 0.0061 16.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC95107.1 - 0.003 16.9 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC95107.1 - 0.083 12.9 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding TPR_1 PF00515.28 EMC95108.1 - 3e-56 185.1 24.2 1e-08 34.6 0.0 10.8 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EMC95108.1 - 7e-51 166.3 16.8 1.3e-06 28.1 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EMC95108.1 - 9.1e-43 140.9 18.2 1.4e-07 31.2 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 EMC95108.1 - 4.5e-31 105.0 12.5 4.7e-05 23.5 0.1 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 EMC95108.1 - 3.2e-29 100.4 21.1 9e-07 28.5 0.9 9.7 6 2 3 9 9 9 6 TPR repeat TPR_19 PF14559.6 EMC95108.1 - 1e-25 90.0 12.2 2.9e-05 24.5 0.0 7.3 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EMC95108.1 - 3.7e-25 88.3 9.6 6.5e-06 26.7 0.0 6.6 6 1 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMC95108.1 - 8.7e-24 82.2 12.7 0.00034 21.2 0.0 9.2 4 3 6 10 10 10 6 Tetratricopeptide repeat TPR_6 PF13174.6 EMC95108.1 - 4.1e-23 80.4 17.4 0.00085 19.8 0.0 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 EMC95108.1 - 1.5e-22 77.9 10.9 0.0078 16.2 0.0 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EMC95108.1 - 2.3e-22 79.1 18.2 2.6e-05 24.4 0.7 7.7 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 EMC95108.1 - 8.7e-14 51.4 12.9 0.00056 20.0 0.1 7.0 3 2 5 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC95108.1 - 3.2e-13 49.7 10.1 1.5e-08 34.7 1.8 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EMC95108.1 - 1.4e-08 34.3 12.5 0.019 14.2 0.4 5.9 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.9 EMC95108.1 - 1e-06 28.6 5.4 0.2 11.4 0.0 4.0 3 2 0 4 4 3 3 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 EMC95108.1 - 0.00026 21.0 0.0 17 5.6 0.0 4.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 EMC95108.1 - 0.00093 18.7 2.6 0.045 13.1 0.1 2.9 2 1 0 2 2 2 1 MalT-like TPR region TPR_20 PF14561.6 EMC95108.1 - 0.0026 18.0 2.7 0.61 10.4 0.0 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.17 EMC95108.1 - 0.0028 18.1 9.9 2.7 8.4 0.1 4.3 4 0 0 4 4 4 2 Bacterial transcriptional activator domain ChAPs PF09295.10 EMC95108.1 - 0.0067 15.5 1.7 4.3 6.2 0.1 3.0 2 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 EMC95108.1 - 0.014 15.1 1.9 1.4 8.6 0.0 3.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 EMC95108.1 - 0.12 12.3 15.8 27 4.8 0.2 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat Clathrin PF00637.20 EMC95108.1 - 0.18 11.7 0.8 11 5.8 0.0 3.3 2 1 1 3 3 3 0 Region in Clathrin and VPS SNAP PF14938.6 EMC95108.1 - 0.66 9.3 17.0 15 4.9 2.1 5.1 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP Pyr_redox_2 PF07992.14 EMC95109.1 - 5.9e-13 48.7 0.0 1e-10 41.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMC95109.1 - 9e-13 47.5 0.0 0.00011 20.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMC95109.1 - 1.6e-07 31.5 0.0 4.5e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EMC95109.1 - 2.1e-06 27.8 0.1 0.00052 20.0 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMC95109.1 - 4.5e-06 26.1 0.0 0.15 11.3 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC95109.1 - 0.00048 19.4 0.1 0.0017 17.6 0.0 1.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EMC95109.1 - 0.00069 18.4 0.3 0.002 16.9 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EMC95109.1 - 0.0012 18.1 0.0 0.0076 15.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EMC95109.1 - 0.0059 17.1 0.7 0.023 15.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMC95109.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EMC95109.1 - 0.019 14.1 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EMC95109.1 - 0.038 13.6 0.2 0.36 10.4 0.5 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase MciZ PF13072.6 EMC95109.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Thi4 PF01946.17 EMC95109.1 - 0.13 11.5 0.1 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 EMC95109.1 - 0.14 12.6 0.0 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_syntA PF00290.20 EMC95110.1 - 1.8e-90 302.3 0.0 2.7e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EMC95110.1 - 1.9e-44 152.3 2.5 3.7e-44 151.3 2.5 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_6 PF13458.6 EMC95110.1 - 0.0066 16.2 0.1 0.017 14.8 0.1 1.8 1 0 0 1 1 1 1 Periplasmic binding protein OGG_N PF07934.12 EMC95113.1 - 6.9e-33 113.3 0.0 1.1e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EMC95113.1 - 8.6e-15 55.1 0.0 1.3e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EMC95113.1 - 0.0031 17.3 0.0 0.0093 15.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif MutS_V PF00488.21 EMC95114.1 - 9.8e-73 244.2 0.0 1.8e-72 243.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMC95114.1 - 3.2e-42 144.9 4.9 9.3e-42 143.4 4.9 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EMC95114.1 - 1.4e-18 67.1 0.0 3.4e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EMC95114.1 - 4.4e-08 33.5 0.0 1.2e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.6 EMC95114.1 - 0.0048 16.9 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Cep57_CLD_2 PF14197.6 EMC95114.1 - 0.086 12.9 3.5 7.4 6.7 0.4 3.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 AAA_29 PF13555.6 EMC95114.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MAM1 PF10434.9 EMC95114.1 - 0.16 11.6 0.0 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 Monopolin complex protein MAM1 AAA_23 PF13476.6 EMC95114.1 - 0.17 12.3 1.0 0.5 10.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain URO-D PF01208.17 EMC95115.1 - 3.6e-129 430.9 0.0 4e-129 430.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.23 EMC95116.1 - 2.6e-22 78.6 0.1 3.9e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMC95116.1 - 1.5e-18 66.8 0.1 1.9e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EMC95116.1 - 0.0018 18.3 2.6 0.11 12.6 1.2 2.3 1 1 1 2 2 2 1 Bd3614-like deaminase SNAD4 PF18750.1 EMC95116.1 - 0.0029 17.7 0.0 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EMC95116.1 - 0.011 15.8 0.0 0.13 12.3 0.0 2.0 1 1 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 EMC95116.1 - 0.017 15.2 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 NAD1 PF18778.1 EMC95116.1 - 0.018 15.2 0.1 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 EMC95116.1 - 0.039 13.8 0.1 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 APOBEC-like N-terminal domain XOO_2897-deam PF14440.6 EMC95116.1 - 0.067 13.3 0.0 0.13 12.3 0.0 1.5 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase Sin3a_C PF16879.5 EMC95117.1 - 7.3e-76 255.6 0.5 8.8e-73 245.5 0.0 3.8 4 0 0 4 4 4 2 C-terminal domain of Sin3a protein PAH PF02671.21 EMC95117.1 - 3.1e-45 152.1 1.3 5.7e-16 58.4 0.0 4.1 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EMC95117.1 - 1.8e-39 133.8 0.0 5e-39 132.3 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Alpha-L-AF_C PF06964.12 EMC95118.1 - 5.5e-27 94.9 0.5 1.2e-26 93.9 0.1 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 EMC95118.1 - 0.0015 18.8 2.2 0.0015 18.8 2.2 2.1 2 1 0 2 2 2 1 Carbohydrate binding domain Peptidase_M75 PF09375.10 EMC95118.1 - 0.077 12.5 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Imelysin Aldolase_II PF00596.21 EMC95119.1 - 3.8e-46 157.4 0.0 7.6e-46 156.4 0.0 1.5 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NAD_binding_10 PF13460.6 EMC95120.1 - 1.9e-08 34.4 0.0 3.9e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EMC95120.1 - 3.6e-07 30.0 0.0 5.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EMC95120.1 - 0.0015 18.8 0.4 0.011 15.9 0.0 2.3 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain DUF3880 PF12996.7 EMC95120.1 - 0.064 13.3 0.1 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 DUF based on E. rectale Gene description (DUF3880) Epimerase PF01370.21 EMC95120.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMC95120.1 - 0.11 11.5 0.0 1.3 7.9 0.0 2.3 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family GST_N_5 PF18485.1 EMC95120.1 - 0.12 12.8 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Pkinase PF00069.25 EMC95121.1 - 5.5e-58 196.4 0.0 7.4e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC95121.1 - 2.5e-43 148.2 0.0 3.8e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EMC95121.1 - 3.6e-09 36.7 0.1 9.4e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EMC95121.1 - 1.5e-06 27.8 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMC95121.1 - 0.049 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EMC95121.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin_4 PF13462.6 EMC95122.1 - 6.8e-11 42.6 0.0 1.9e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EMC95122.1 - 0.027 14.3 1.2 0.23 11.2 0.4 2.4 1 1 1 2 2 2 0 DSBA-like thioredoxin domain HATPase_c_3 PF13589.6 EMC95123.1 - 3.5e-10 39.8 0.1 6.5e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EMC95123.1 - 2.1e-09 37.1 0.0 4.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EMC95123.1 - 6.6e-08 33.0 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Transferase PF02458.15 EMC95124.1 - 1.5e-16 60.1 0.0 2e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Transferase family DUF1776 PF08643.10 EMC95125.1 - 1.3e-59 202.0 0.1 2.1e-51 175.1 0.1 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.25 EMC95125.1 - 5.2e-06 26.0 0.0 9.8e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC95125.1 - 1e-05 25.2 0.0 3.2e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase RRM_1 PF00076.22 EMC95127.1 - 4.5e-28 96.9 0.1 1.5e-11 43.9 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC95127.1 - 7.9e-06 25.7 0.1 0.64 9.9 0.0 3.6 4 0 0 4 4 4 2 Occluded RNA-recognition motif HTH_32 PF13565.6 EMC95129.1 - 1.2e-05 25.8 6.6 1.7e-05 25.3 0.2 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_36 PF13730.6 EMC95129.1 - 0.00023 21.1 0.0 0.00055 19.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 EMC95129.1 - 0.0025 17.8 0.5 0.0025 17.8 0.5 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 EMC95129.1 - 0.0058 16.9 0.2 0.021 15.1 0.2 2.0 1 0 0 1 1 1 1 Transposase SF1-HH PF16275.5 EMC95129.1 - 0.042 14.2 3.3 0.1 12.9 3.3 1.7 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain Calreticulin PF00262.18 EMC95130.1 - 1.2e-170 567.2 12.9 1.6e-170 566.9 12.9 1.1 1 0 0 1 1 1 1 Calreticulin family LapA_dom PF06305.11 EMC95130.1 - 0.017 14.9 0.2 0.052 13.4 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ABA_WDS PF02496.16 EMC95130.1 - 0.19 12.2 2.8 0.51 10.9 0.7 2.8 3 0 0 3 3 3 0 ABA/WDS induced protein Tape_meas_lam_C PF09718.10 EMC95130.1 - 0.32 11.2 3.6 2 8.6 0.3 2.3 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) OAD_gamma PF04277.13 EMC95130.1 - 0.46 11.1 4.5 0.67 10.6 0.2 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain FAD_binding_3 PF01494.19 EMC95131.1 - 7.1e-19 68.2 0.4 1.1e-18 67.7 0.4 1.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EMC95131.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EMC95131.1 - 0.0013 18.9 0.2 0.0061 16.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMC95131.1 - 0.033 13.5 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EMC95131.1 - 0.034 13.4 1.3 1.2 8.3 0.4 2.8 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC95131.1 - 0.054 12.8 0.0 6.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMC95131.1 - 0.21 10.6 3.7 0.67 8.9 0.4 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EMC95131.1 - 0.55 9.7 4.2 4.8 6.6 1.7 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase HVSL PF09749.9 EMC95132.1 - 2.6e-41 141.7 0.0 3.1e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 EMC95132.1 - 0.0021 18.0 0.1 0.0028 17.6 0.1 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily FbpC_C_terminal PF17845.1 EMC95132.1 - 0.084 13.0 0.1 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain Pal1 PF08316.11 EMC95133.1 - 1e-08 36.1 1.9 3.1e-08 34.5 0.1 2.4 2 0 0 2 2 2 1 Pal1 cell morphology protein Aldedh PF00171.22 EMC95134.1 - 7.3e-137 456.6 1.1 9.3e-137 456.3 1.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EMC95134.1 - 0.011 14.8 0.1 0.04 13.0 0.0 2.0 3 0 0 3 3 3 0 Acyl-CoA reductase (LuxC) DUF1344 PF07076.11 EMC95134.1 - 0.032 14.1 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) FAD_binding_3 PF01494.19 EMC95135.1 - 9.3e-14 51.4 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EMC95135.1 - 0.0025 16.8 0.0 0.0041 16.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 EMC95135.1 - 0.0089 15.3 0.0 0.041 13.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMC95135.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ABM PF03992.16 EMC95136.1 - 0.017 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase FAA_hydrolase PF01557.18 EMC95137.1 - 1.1e-54 185.4 0.0 1.5e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EMC95137.1 - 9.8e-29 99.7 0.0 1.8e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Abhydrolase_6 PF12697.7 EMC95138.1 - 3e-14 54.1 0.2 3.9e-14 53.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC95138.1 - 3.9e-05 23.4 0.1 0.00019 21.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC95138.1 - 0.0011 18.3 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 EMC95138.1 - 0.22 10.0 0.0 0.3 9.5 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Fungal_trans PF04082.18 EMC95140.1 - 1.5e-22 79.9 0.8 3.3e-22 78.8 0.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain PQ-loop PF04193.14 EMC95140.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 PQ loop repeat AMP-binding PF00501.28 EMC95141.1 - 4.7e-85 285.7 0.0 5.5e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC95141.1 - 3.2e-09 37.6 0.2 7.6e-09 36.4 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 EMC95142.1 - 0.00012 21.6 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EMC95142.1 - 0.25 10.5 0.0 7 5.7 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Dabb PF07876.12 EMC95143.1 - 1.9e-12 47.6 0.3 2.3e-12 47.4 0.3 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ribosomal_S4e PF00900.20 EMC95143.1 - 0.07 13.0 0.1 0.1 12.6 0.1 1.4 1 1 0 1 1 1 0 Ribosomal family S4e SpuA_C PF18033.1 EMC95143.1 - 0.1 12.6 0.1 0.27 11.3 0.0 1.7 1 1 1 2 2 2 0 SpuA C-terminal Aldedh PF00171.22 EMC95144.1 - 1.7e-138 462.0 0.0 1.9e-138 461.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMC95144.1 - 0.031 13.7 0.0 4.1 6.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1487) MFS_1 PF07690.16 EMC95145.1 - 1.3e-28 100.0 38.7 1.3e-28 100.0 38.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily HgmA PF04209.13 EMC95146.1 - 2.4e-197 655.8 0.1 2.8e-197 655.6 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Acyl-CoA_dh_1 PF00441.24 EMC95147.1 - 3.1e-37 128.1 0.5 4.3e-37 127.6 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMC95147.1 - 7.1e-19 67.8 0.1 1.3e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMC95147.1 - 5.8e-10 39.6 0.0 9.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMC95147.1 - 1.7e-09 38.3 0.0 3.6e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF1751 PF08551.10 EMC95151.1 - 3.1e-24 85.4 0.2 7e-24 84.3 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EMC95151.1 - 2.2e-05 24.5 4.4 5e-05 23.3 4.4 1.6 1 0 0 1 1 1 1 Rhomboid family LisH PF08513.11 EMC95152.1 - 4.6e-07 29.6 0.3 1e-06 28.5 0.3 1.6 1 0 0 1 1 1 1 LisH FMO-like PF00743.19 EMC95153.1 - 3.4e-13 48.9 0.0 7.5e-12 44.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMC95153.1 - 4.5e-10 39.6 0.0 9.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EMC95153.1 - 8.7e-05 21.8 0.0 0.008 15.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EMC95153.1 - 9.9e-05 22.1 0.0 1.7 8.1 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMC95153.1 - 0.00015 21.2 0.0 0.0012 18.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC95153.1 - 0.00022 20.5 0.0 0.037 13.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC95153.1 - 0.0026 17.8 0.1 0.033 14.2 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 EMC95153.1 - 0.053 12.6 0.0 3.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 EMC95153.1 - 0.058 12.1 0.0 0.097 11.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF4187 PF13821.6 EMC95155.1 - 1.2e-21 76.2 1.7 3.2e-21 74.8 1.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EMC95155.1 - 7e-09 35.4 3.2 1.2e-08 34.7 3.2 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EMC95155.1 - 0.057 13.5 2.3 0.19 11.8 2.3 2.0 1 0 0 1 1 1 0 G-patch domain FMN_red PF03358.15 EMC95156.1 - 1.4e-08 34.6 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EMC95156.1 - 5.2e-05 23.1 0.0 6.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EMC95156.1 - 0.0016 18.6 0.0 0.088 13.0 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EMC95156.1 - 0.067 13.4 0.0 0.45 10.7 0.0 2.0 1 1 1 2 2 2 0 Flavodoxin domain F_actin_cap_B PF01115.17 EMC95157.1 - 2.2e-92 309.0 0.0 2.5e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Rep_fac_C PF08542.11 EMC95158.1 - 1.9e-16 60.3 0.0 3.8e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EMC95158.1 - 7.6e-15 55.5 0.0 1.9e-14 54.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EMC95158.1 - 1.8e-12 47.4 0.0 5.7e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EMC95158.1 - 8.2e-08 32.4 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EMC95158.1 - 2e-05 25.1 0.0 0.00041 20.8 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMC95158.1 - 2.6e-05 24.5 0.0 0.00013 22.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMC95158.1 - 2.7e-05 24.1 0.0 7.2e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMC95158.1 - 5.5e-05 23.0 0.0 0.00015 21.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 EMC95158.1 - 0.00016 21.9 0.1 0.00057 20.2 0.1 2.0 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 EMC95158.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EMC95158.1 - 0.0019 17.6 0.0 0.078 12.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EMC95158.1 - 0.0026 17.5 0.0 0.009 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EMC95158.1 - 0.0026 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EMC95158.1 - 0.0043 17.0 0.1 0.035 14.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EMC95158.1 - 0.0088 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EMC95158.1 - 0.0092 16.0 0.0 0.024 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMC95158.1 - 0.0095 16.1 0.0 0.28 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMC95158.1 - 0.013 15.2 0.0 0.1 12.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EMC95158.1 - 0.013 15.8 0.0 0.083 13.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMC95158.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EMC95158.1 - 0.034 13.4 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 EMC95158.1 - 0.05 14.1 0.0 0.17 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EMC95158.1 - 0.055 13.5 0.0 0.17 11.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EMC95158.1 - 0.066 13.0 0.1 0.83 9.4 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase TIP49 PF06068.13 EMC95158.1 - 0.071 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 EMC95158.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 EMC95158.1 - 0.12 12.2 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_60s PF00428.19 EMC95158.1 - 0.46 11.1 7.4 4.4 8.0 0.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1746 PF08508.10 EMC95159.1 - 2.6e-44 150.2 0.1 3.6e-44 149.8 0.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Zip PF02535.22 EMC95160.1 - 7.5e-50 170.0 0.0 1.1e-49 169.5 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter CBS PF00571.28 EMC95161.1 - 4.1e-07 30.3 0.2 0.086 13.3 0.2 3.1 2 1 0 2 2 2 2 CBS domain Mito_carr PF00153.27 EMC95162.1 - 2.7e-42 142.6 5.3 9.6e-15 54.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3602 PF12223.8 EMC95163.1 - 1.7e-15 57.4 13.6 2.5e-12 47.2 3.8 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) RelB_transactiv PF16181.5 EMC95164.1 - 0.052 13.8 0.3 0.09 13.0 0.3 1.3 1 0 0 1 1 1 0 RelB transactivation domain PTP2 PF17022.5 EMC95164.1 - 0.11 12.1 0.4 0.16 11.6 0.4 1.2 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia LANC_like PF05147.13 EMC95165.1 - 1.4e-30 106.1 0.0 2.8e-30 105.1 0.0 1.5 2 0 0 2 2 2 1 Lanthionine synthetase C-like protein Pec_lyase PF09492.10 EMC95165.1 - 0.0067 15.8 0.0 0.019 14.3 0.0 1.6 1 1 0 1 1 1 1 Pectic acid lyase V-SNARE_C PF12352.8 EMC95166.1 - 0.35 11.2 9.0 0.64 10.3 0.8 3.1 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus HET PF06985.11 EMC95167.1 - 9.1e-26 91.0 0.0 1.1e-25 90.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M23 PF01551.22 EMC95167.1 - 0.065 13.5 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M23 PAS_6 PF08348.11 EMC95167.1 - 0.23 11.3 0.3 0.73 9.7 0.1 1.8 1 1 1 2 2 2 0 YheO-like PAS domain DUF1295 PF06966.12 EMC95168.1 - 5.4e-53 179.9 1.3 9.3e-53 179.2 1.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EMC95168.1 - 2e-07 31.1 3.1 2.7e-06 27.5 0.1 3.0 1 1 2 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EMC95168.1 - 3.8e-05 24.0 0.1 3.8e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EMC95168.1 - 0.0033 17.8 0.4 0.038 14.4 0.1 2.6 1 1 1 2 2 2 1 Phospholipid methyltransferase PepX_N PF09168.10 EMC95168.1 - 0.0079 16.6 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal DUF3807 PF12720.7 EMC95169.1 - 1.9e-28 100.0 2.4 2.5e-28 99.6 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) PepSY PF03413.19 EMC95169.1 - 0.17 12.5 0.2 3.6 8.2 0.1 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain IQCJ-SCHIP1 PF15157.6 EMC95170.1 - 0.012 15.4 0.1 0.3 10.9 0.1 2.1 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif VRR_NUC PF08774.11 EMC95171.1 - 9.8e-21 73.9 0.0 2.6e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Fasciclin PF02469.22 EMC95172.1 - 0.044 14.0 0.0 0.065 13.5 0.0 1.5 1 1 0 1 1 1 0 Fasciclin domain COPIIcoated_ERV PF07970.12 EMC95173.1 - 5.7e-86 287.9 0.0 1.1e-85 287.0 0.0 1.4 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EMC95173.1 - 5.5e-30 103.6 0.0 3.4e-29 101.0 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2417 PF10329.9 EMC95174.1 - 3e-91 305.0 0.0 4e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) m04gp34like PF12216.8 EMC95174.1 - 0.074 12.6 0.3 0.14 11.7 0.1 1.6 2 0 0 2 2 2 0 Immune evasion protein EVI2A PF05399.11 EMC95174.1 - 0.47 10.0 7.1 1.9 8.0 0.1 2.6 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) ECSCR PF15820.5 EMC95174.1 - 1.8 8.4 3.7 47 3.9 0.5 3.2 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator Abhydrolase_6 PF12697.7 EMC95175.1 - 4.3e-21 76.5 4.3 4.3e-21 76.5 4.3 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC95175.1 - 4.4e-08 33.1 0.2 2e-07 30.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC95175.1 - 2.9e-05 23.5 0.1 4.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMC95175.1 - 0.0019 18.4 2.6 0.013 15.7 2.6 2.5 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 EMC95175.1 - 0.068 13.0 0.5 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 Lipase (class 3) Fcf1 PF04900.12 EMC95176.1 - 1e-28 99.6 0.2 1.5e-28 99.1 0.2 1.2 1 0 0 1 1 1 1 Fcf1 DUF726 PF05277.12 EMC95177.1 - 7.6e-119 396.6 4.6 1.1e-118 396.1 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF1761 PF08570.10 EMC95177.1 - 0.051 13.8 0.5 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) FAD_binding_3 PF01494.19 EMC95178.1 - 1.8e-20 73.5 0.0 2.7e-19 69.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC95178.1 - 3.6e-08 33.4 0.8 0.0005 19.8 0.2 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC95178.1 - 2.5e-05 23.7 0.0 3.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC95178.1 - 0.00021 21.4 0.1 0.00052 20.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC95178.1 - 0.00041 20.8 0.4 0.077 13.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC95178.1 - 0.029 13.5 0.3 0.052 12.6 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EMC95178.1 - 0.033 13.3 0.4 0.2 10.7 0.3 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EMC95178.1 - 0.088 11.9 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 EMC95178.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SE PF08491.10 EMC95178.1 - 0.2 10.7 0.0 1.2 8.2 0.0 2.2 1 1 0 1 1 1 0 Squalene epoxidase Myb_DNA-binding PF00249.31 EMC95179.1 - 1.2e-07 31.7 0.2 2.4e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC95179.1 - 0.00047 20.3 0.0 0.00089 19.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMC95180.1 - 9.3e-05 22.5 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC95180.1 - 0.042 14.1 0.0 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain TcA_RBD PF18518.1 EMC95181.1 - 0.19 12.1 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 TcA receptor binding domain Calcipressin PF04847.12 EMC95182.1 - 8.1e-40 136.6 0.4 1.6e-39 135.6 0.4 1.4 1 1 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.8 EMC95182.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Utp12 PF04003.12 EMC95186.1 - 5.2e-25 87.8 0.0 7.3e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Nop14 PF04147.12 EMC95186.1 - 3.2 5.9 34.1 5.7 5.0 32.6 1.8 2 0 0 2 2 2 0 Nop14-like family Bromodomain PF00439.25 EMC95187.1 - 5.4e-39 132.1 0.1 9.5e-19 67.3 0.0 2.2 2 0 0 2 2 2 2 Bromodomain DUF1194 PF06707.11 EMC95188.1 - 0.0043 16.3 0.0 0.0049 16.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) AMP-binding PF00501.28 EMC95189.1 - 6.7e-58 196.3 0.0 9.3e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC95189.1 - 1.5e-07 32.3 0.0 4e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 EMC95189.1 - 0.00012 22.3 0.0 0.0003 21.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 EMC95189.1 - 0.00037 19.3 0.2 0.00087 18.1 0.2 1.6 1 1 0 1 1 1 1 Condensation domain RNase_P_p30 PF01876.16 EMC95190.1 - 2.1e-58 197.3 0.0 2.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 DUF5476 PF17570.2 EMC95190.1 - 0.018 15.4 0.7 1 9.8 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5476) Fungal_trans PF04082.18 EMC95191.1 - 7.9e-23 80.8 0.0 1.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC95191.1 - 0.0026 17.9 10.6 0.0049 17.0 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 EMC95192.1 - 5.6e-29 101.8 0.0 7.6e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.6 EMC95192.1 - 0.0056 16.9 0.0 0.0098 16.2 0.0 1.3 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 GFA PF04828.14 EMC95193.1 - 1.8e-15 57.0 0.4 1.8e-15 57.0 0.4 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cupin_2 PF07883.11 EMC95194.1 - 3.1e-10 39.6 0.4 4.6e-10 39.1 0.4 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EMC95194.1 - 0.0039 16.8 0.1 0.0043 16.7 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 EMC95194.1 - 0.0056 16.4 0.1 0.0077 16.0 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EMC95194.1 - 0.067 12.9 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Mannosyl_trans3 PF11051.8 EMC95196.1 - 1.8e-49 168.5 0.0 8.9e-47 159.7 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative Methyltransf_25 PF13649.6 EMC95198.1 - 3.3e-06 27.7 0.1 5.4e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC95198.1 - 8e-06 25.7 0.1 8.7e-06 25.6 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC95198.1 - 9e-06 26.3 0.2 1.8e-05 25.3 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC95198.1 - 0.00072 20.3 0.0 0.0014 19.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EMC95198.1 - 0.045 13.9 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EMC95198.1 - 0.098 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain COesterase PF00135.28 EMC95199.1 - 2.1e-77 261.2 0.0 3.6e-77 260.4 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC95199.1 - 8.5e-06 25.8 0.1 4.4e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold WD40 PF00400.32 EMC95200.1 - 2.1e-13 50.5 10.6 0.0089 16.9 1.5 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC95200.1 - 2e-06 28.0 0.5 0.011 16.0 0.2 3.9 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC95200.1 - 6.1e-05 21.9 4.0 0.029 13.0 0.4 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EMC95200.1 - 0.042 12.6 0.2 4.8 5.8 0.0 3.0 2 1 0 3 3 3 0 Nup133 N terminal like RRF PF01765.19 EMC95201.1 - 5.9e-39 133.6 1.7 7.5e-39 133.3 1.7 1.1 1 0 0 1 1 1 1 Ribosome recycling factor PIN_6 PF17146.4 EMC95201.1 - 0.087 13.3 0.4 3 8.4 0.1 2.4 1 1 0 2 2 2 0 PIN domain of ribonuclease TFIIS_M PF07500.14 EMC95202.1 - 3.3e-28 98.4 1.0 6.8e-28 97.4 1.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EMC95202.1 - 1.3e-17 63.3 9.6 2.4e-17 62.5 9.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EMC95202.1 - 7.8e-13 48.2 0.3 1.8e-12 47.0 0.3 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CGGC PF08821.11 EMC95202.1 - 0.034 14.3 2.3 0.61 10.3 2.5 2.2 2 0 0 2 2 2 0 CGGC domain MFS_1 PF07690.16 EMC95205.1 - 9e-28 97.2 31.4 9e-28 97.2 31.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Tannase PF07519.11 EMC95206.1 - 6.1e-86 289.2 1.8 8.2e-86 288.8 1.8 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EMC95206.1 - 0.00056 19.4 0.7 0.074 12.5 0.6 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EMC95206.1 - 0.01 15.5 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC95206.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AtuA PF07287.11 EMC95207.1 - 1.9e-128 428.1 0.1 2.4e-128 427.8 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Sec66 PF09802.9 EMC95208.1 - 5.3e-77 257.5 1.3 6.2e-77 257.3 1.3 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3050 PF11251.8 EMC95208.1 - 0.015 14.9 0.1 0.04 13.5 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3050) DUF3848 PF12959.7 EMC95208.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) RGS_DHEX PF18148.1 EMC95208.1 - 0.11 12.6 5.2 0.079 13.1 3.2 1.7 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain SMC_ScpA PF02616.14 EMC95208.1 - 0.42 10.5 4.4 3.4 7.5 0.7 2.1 2 0 0 2 2 2 0 Segregation and condensation protein ScpA NPL4 PF05021.15 EMC95209.1 - 9.7e-133 442.2 0.0 1.2e-132 441.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EMC95209.1 - 2.9e-72 241.5 0.4 4.5e-72 240.9 0.4 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Sel1 PF08238.12 EMC95210.1 - 1.2e-10 41.7 16.3 0.00023 21.8 1.9 4.1 4 0 0 4 4 4 3 Sel1 repeat Pkinase PF00069.25 EMC95211.1 - 4.7e-55 186.8 0.0 5.8e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC95211.1 - 1.1e-35 123.2 0.0 1.5e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC95211.1 - 1e-08 34.9 0.0 5.4e-08 32.5 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMC95211.1 - 0.047 12.5 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EMC95211.1 - 0.047 13.3 0.2 0.9 9.1 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PGP_phosphatase PF09419.10 EMC95211.1 - 0.05 13.2 0.1 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase RRN3 PF05327.11 EMC95214.1 - 5.4e-156 520.4 0.0 7.5e-156 519.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DnaJ_C PF01556.18 EMC95216.1 - 1.4e-39 135.6 0.2 1.8e-39 135.2 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMC95216.1 - 5.2e-27 93.8 0.6 9.9e-27 92.9 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMC95216.1 - 1.7e-16 60.3 19.9 3e-16 59.5 19.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EMC95216.1 - 0.49 10.4 11.7 0.6 10.2 3.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2614 PF11023.8 EMC95216.1 - 0.5 10.5 7.0 5.2 7.2 0.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc_ribbon_9 PF14369.6 EMC95216.1 - 3.2 8.1 6.9 33 4.8 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon zinc-ribbons_6 PF07191.12 EMC95216.1 - 3.3 7.7 10.3 5.3 7.1 3.1 2.3 1 1 0 2 2 2 0 zinc-ribbons DUF1674 PF07896.12 EMC95217.1 - 9.3e-19 67.7 3.8 9.3e-19 67.7 3.8 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) ORC6 PF05460.13 EMC95217.1 - 0.026 13.8 1.5 0.029 13.7 1.5 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AC_N PF16214.5 EMC95217.1 - 0.18 10.9 0.7 0.22 10.6 0.7 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region HAUS4 PF14735.6 EMC95218.1 - 1.1e-09 38.4 11.6 1.5e-09 37.9 11.6 1.3 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 Vac_Fusion PF02346.16 EMC95218.1 - 0.06 13.0 1.2 0.49 10.0 0.1 2.9 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 CTP_transf_3 PF02348.19 EMC95218.1 - 0.06 13.2 3.1 0.084 12.8 3.1 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Aconitase_B_N PF11791.8 EMC95218.1 - 0.16 12.0 3.7 0.12 12.5 1.0 2.4 2 1 0 2 2 2 0 Aconitate B N-terminal domain Fib_alpha PF08702.10 EMC95218.1 - 5.4 7.2 9.7 1.2 9.3 3.7 2.7 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.8 EMC95218.1 - 7.5 6.7 7.5 0.8 9.8 0.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF2407_C PF13373.6 EMC95219.1 - 2.3e-42 144.5 0.1 3.5e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EMC95219.1 - 4.5e-29 101.1 0.0 8.1e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EMC95219.1 - 1.3e-06 28.0 0.0 4.3e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EMC95219.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Dabb PF07876.12 EMC95220.1 - 6.7e-24 84.4 0.0 7.4e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fe-S_biosyn PF01521.20 EMC95221.1 - 7.9e-20 71.1 0.0 1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis TIP49 PF06068.13 EMC95222.1 - 5.4e-162 538.9 0.0 6.9e-162 538.6 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EMC95222.1 - 1.7e-13 50.4 0.0 4.4e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EMC95222.1 - 7.6e-12 45.8 0.1 2.9e-07 30.9 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EMC95222.1 - 2.2e-10 40.5 0.1 4.1e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMC95222.1 - 1.4e-05 25.4 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EMC95222.1 - 9.8e-05 22.7 0.1 0.038 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMC95222.1 - 0.00019 21.9 0.1 0.0013 19.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EMC95222.1 - 0.00041 20.4 0.2 0.083 12.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EMC95222.1 - 0.0019 18.0 0.1 1.5 8.5 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 EMC95222.1 - 0.0022 17.3 0.6 0.0074 15.6 0.3 1.9 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 EMC95222.1 - 0.0066 15.9 0.2 0.31 10.4 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMC95222.1 - 0.01 15.4 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMC95222.1 - 0.011 16.0 0.1 0.02 15.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EMC95222.1 - 0.023 13.9 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 EMC95222.1 - 0.03 14.8 0.2 0.083 13.3 0.1 1.8 2 0 0 2 2 1 0 AAA domain DnaB_C PF03796.15 EMC95222.1 - 0.034 13.5 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 EMC95222.1 - 0.041 13.6 0.1 0.077 12.7 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EMC95222.1 - 0.052 13.1 0.3 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EMC95222.1 - 0.063 12.3 0.5 0.4 9.7 0.1 2.0 1 1 1 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 EMC95222.1 - 0.065 12.6 0.1 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 EMC95222.1 - 0.08 13.5 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMC95222.1 - 0.084 12.6 0.6 1.8 8.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain Chitin_synth_2 PF03142.15 EMC95223.1 - 1.3e-286 951.4 0.3 6.3e-286 949.1 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EMC95223.1 - 1e-12 48.4 1.2 3.9e-12 46.5 1.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMC95223.1 - 4.4e-11 43.1 0.0 9.3e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMC95223.1 - 0.00083 18.9 0.0 0.035 13.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EMC95223.1 - 0.0027 17.5 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.12 EMC95225.1 - 2.4e-35 120.2 23.4 4e-05 24.1 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat WD40 PF00400.32 EMC95228.1 - 0.011 16.6 13.4 0.031 15.2 0.1 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC95228.1 - 0.058 13.7 0.1 8 6.8 0.0 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Atg14 PF10186.9 EMC95229.1 - 1e-50 172.7 0.0 1.4e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 RasGAP_C PF03836.15 EMC95229.1 - 0.0019 18.3 0.3 0.0032 17.6 0.3 1.3 1 0 0 1 1 1 1 RasGAP C-terminus Calx-beta PF03160.14 EMC95230.1 - 0.24 11.6 0.0 0.27 11.4 0.0 1.0 1 0 0 1 1 1 0 Calx-beta domain AAA PF00004.29 EMC95233.1 - 1.9e-39 135.1 0.0 3.2e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMC95233.1 - 9e-11 41.4 0.2 2.4e-10 40.0 0.2 1.8 1 1 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EMC95233.1 - 1.4e-05 25.6 0.1 0.00041 20.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMC95233.1 - 2.8e-05 24.4 0.1 0.0097 16.2 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EMC95233.1 - 4.2e-05 23.4 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EMC95233.1 - 0.00043 19.6 0.0 0.00071 18.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EMC95233.1 - 0.0005 20.1 0.1 0.0015 18.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EMC95233.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMC95233.1 - 0.0022 18.2 0.0 0.0052 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMC95233.1 - 0.0048 17.3 0.1 0.014 15.8 0.0 1.8 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.21 EMC95233.1 - 0.0052 16.2 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EMC95233.1 - 0.007 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EMC95233.1 - 0.0076 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMC95233.1 - 0.0086 16.6 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMC95233.1 - 0.0089 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EMC95233.1 - 0.0099 16.0 0.0 0.036 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EMC95233.1 - 0.017 14.8 0.1 0.04 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EMC95233.1 - 0.032 13.6 0.0 0.72 9.2 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein Hydin_ADK PF17213.3 EMC95233.1 - 0.042 14.1 1.7 3.7 7.8 0.1 2.6 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 EMC95233.1 - 0.065 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMC95233.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 EMC95233.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IPT PF01745.16 EMC95233.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase ABC_tran PF00005.27 EMC95233.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DUF1517 PF07466.11 EMC95233.1 - 0.11 12.6 0.1 0.32 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Parvo_NS1 PF01057.17 EMC95233.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EMC95233.1 - 0.13 11.6 0.3 0.29 10.6 0.3 1.5 1 1 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 EMC95233.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EMC95233.1 - 0.17 11.4 0.1 0.42 10.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region SHQ1 PF04925.15 EMC95233.1 - 0.18 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 SHQ1 protein Nfu_N PF08712.11 EMC95234.1 - 1.8e-27 95.2 0.0 1.9e-26 92.0 0.0 2.2 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EMC95234.1 - 2.9e-27 94.6 0.1 5.2e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain DUF4050 PF13259.6 EMC95236.1 - 1.7e-46 158.8 8.2 1.7e-46 158.8 8.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4050) Macoilin PF09726.9 EMC95236.1 - 1.9 6.9 7.4 2.4 6.6 7.4 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_S8 PF00082.22 EMC95237.1 - 2.7e-34 118.8 1.5 3.9e-34 118.3 1.5 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EMC95237.1 - 4.4e-28 97.1 2.1 9e-28 96.1 2.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 EMC95237.1 - 0.0052 17.5 0.6 0.013 16.2 0.6 1.7 1 0 0 1 1 1 1 Peptidase S8 pro-domain PhoD PF09423.10 EMC95238.1 - 1.8e-06 27.2 0.1 0.00058 19.0 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase tRNA-synt_1 PF00133.22 EMC95239.1 - 1.2e-39 136.1 0.0 2.3e-29 102.1 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EMC95239.1 - 1.9e-15 56.6 0.0 7.5e-10 38.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EMC95239.1 - 5e-12 46.0 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EMC95239.1 - 1.4e-07 31.2 0.0 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain p450 PF00067.22 EMC95242.1 - 3.2e-25 88.8 0.0 6.1e-25 87.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 GNAT_acetyltr_2 PF13718.6 EMC95243.1 - 3.1e-98 327.7 0.0 6.4e-98 326.7 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EMC95243.1 - 3.4e-80 269.1 0.0 6.2e-80 268.3 0.0 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EMC95243.1 - 7.2e-66 221.4 0.0 1.1e-64 217.6 0.0 2.6 3 0 0 3 3 3 1 Helicase DUF1726 PF08351.11 EMC95243.1 - 4.3e-33 113.1 0.0 1.2e-32 111.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EMC95243.1 - 0.00015 21.6 0.1 0.027 14.2 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMC95243.1 - 0.0015 18.8 0.0 0.47 10.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain Acetyltransf_1 PF00583.25 EMC95243.1 - 0.037 14.3 0.0 0.33 11.2 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC95243.1 - 0.053 14.0 0.0 0.42 11.1 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_19 PF13245.6 EMC95243.1 - 0.15 12.4 0.0 0.58 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain SpoIIE PF07228.12 EMC95244.1 - 0.00025 21.0 0.1 0.0008 19.4 0.1 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EMC95244.1 - 0.00061 19.5 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EMC95244.1 - 0.018 14.7 0.0 1.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Protein phosphatase 2C Ctr PF04145.15 EMC95245.1 - 2e-14 54.5 4.1 9.1e-13 49.1 4.1 2.0 1 1 0 1 1 1 1 Ctr copper transporter family ORC3_N PF07034.11 EMC95246.1 - 1.8e-31 109.5 0.0 1e-29 103.7 0.0 2.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EMC95246.1 - 3.5e-30 104.9 1.3 1e-18 67.7 0.0 2.6 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal DUF3844 PF12955.7 EMC95248.1 - 1.1e-33 115.5 3.5 1.9e-33 114.7 3.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Sugar_tr PF00083.24 EMC95249.1 - 3.5e-83 280.0 19.5 4e-83 279.8 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC95249.1 - 3e-13 49.5 32.1 8.5e-10 38.1 26.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMC95249.1 - 0.00025 20.0 14.5 0.0016 17.4 4.3 2.3 2 0 0 2 2 2 2 MFS_1 like family Tetraspanin PF00335.20 EMC95249.1 - 0.0071 16.1 2.4 0.0071 16.1 2.4 2.0 2 0 0 2 2 2 1 Tetraspanin family PX PF00787.24 EMC95251.1 - 1.4e-18 66.9 1.1 4.3e-18 65.4 0.1 2.2 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 EMC95251.1 - 2.3e-11 43.7 10.1 2e-05 24.2 0.8 2.1 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EMC95251.1 - 3.5e-05 23.6 5.9 0.00028 20.6 5.7 2.2 2 1 0 2 2 2 1 BAR domain Sec34 PF04136.15 EMC95251.1 - 0.004 17.1 1.8 0.008 16.1 0.1 2.2 2 2 1 3 3 3 1 Sec34-like family DUF1664 PF07889.12 EMC95251.1 - 0.55 10.3 3.6 5.6 7.0 1.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.19 EMC95251.1 - 0.56 8.0 11.7 0.68 7.7 0.5 2.1 1 1 0 2 2 2 0 Myosin tail APG6_N PF17675.1 EMC95251.1 - 0.76 10.3 11.3 4.6 7.8 0.1 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EMC95251.1 - 1.3 9.2 6.5 15 5.8 3.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TerB PF05099.13 EMC95251.1 - 4.8 7.1 9.2 0.63 10.0 1.6 3.0 4 0 0 4 4 4 0 Tellurite resistance protein TerB DUF948 PF06103.11 EMC95251.1 - 6 7.2 6.0 31 4.9 0.3 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.13 EMC95251.1 - 6.3 7.6 6.5 7.8 7.3 0.0 3.0 3 1 0 3 3 3 0 Occludin homology domain Syntaxin PF00804.25 EMC95252.1 - 0.036 13.7 11.5 0.072 12.7 10.0 2.2 1 1 1 2 2 2 0 Syntaxin Baculo_PEP_C PF04513.12 EMC95252.1 - 0.051 13.6 5.0 1.2 9.2 0.2 2.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YvfG PF09628.10 EMC95252.1 - 0.071 13.5 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 YvfG protein NPV_P10 PF05531.12 EMC95252.1 - 0.42 11.1 9.0 5.6 7.5 0.4 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.11 EMC95252.1 - 0.46 10.0 2.9 0.53 9.8 1.7 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein AAA_13 PF13166.6 EMC95252.1 - 0.48 9.0 14.6 1.4 7.4 14.6 1.6 1 1 0 1 1 1 0 AAA domain Leu_zip PF15294.6 EMC95252.1 - 0.81 9.2 15.7 6 6.3 15.1 2.0 1 1 0 1 1 1 0 Leucine zipper DUF1664 PF07889.12 EMC95252.1 - 0.82 9.7 12.8 0.3 11.1 1.0 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EMC95252.1 - 1.5 9.3 12.7 3.5 8.2 0.4 2.5 1 1 0 2 2 2 0 Protein of unknown function DUF16 bZIP_1 PF00170.21 EMC95252.1 - 1.6 8.8 9.7 12 6.0 0.0 4.0 3 1 1 4 4 4 0 bZIP transcription factor DUF948 PF06103.11 EMC95252.1 - 3.5 8.0 8.8 3.4 8.0 2.0 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 EMC95252.1 - 3.5 5.5 4.7 2.9 5.7 3.4 1.5 1 1 1 2 2 2 0 Prominin MbeD_MobD PF04899.12 EMC95252.1 - 4 7.6 6.6 0.75 10.0 0.9 2.7 3 1 0 3 3 2 0 MbeD/MobD like Muted PF14942.6 EMC95252.1 - 4.6 7.6 12.0 20 5.5 7.5 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TSNAXIP1_N PF15739.5 EMC95252.1 - 5.3 7.5 10.1 0.74 10.2 0.1 2.8 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF3782 PF12644.7 EMC95252.1 - 8.6 6.6 7.8 1.7 8.8 0.1 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF3782) Helicase_C PF00271.31 EMC95253.1 - 3.2e-31 107.9 0.1 4e-30 104.4 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMC95253.1 - 1.2e-22 80.5 0.0 2.1e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 EMC95253.1 - 0.0057 16.0 0.1 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 EMC95253.1 - 0.044 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain fragilysinNterm PF16376.5 EMC95253.1 - 0.069 12.9 0.1 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of fragilysin Cupin_8 PF13621.6 EMC95254.1 - 5.6e-16 59.0 0.0 3e-14 53.4 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EMC95254.1 - 3.1e-10 40.5 0.0 4.9e-09 36.6 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase tRNA-synt_2c PF01411.19 EMC95255.1 - 7e-217 721.3 0.7 9.5e-217 720.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) FAA_hydrolase PF01557.18 EMC95255.1 - 1.2e-46 159.2 0.0 2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family tRNA_SAD PF07973.14 EMC95255.1 - 4.3e-18 65.1 0.8 1.1e-17 63.8 0.8 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EMC95255.1 - 3.2e-09 37.3 6.8 8.7e-09 35.9 6.8 1.8 1 0 0 1 1 1 1 DHHA1 domain Glyco_hydro_16 PF00722.21 EMC95257.1 - 4.7e-05 22.9 0.1 4.7e-05 22.9 0.1 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Presenilin PF01080.17 EMC95257.1 - 5.6 5.6 12.3 8.3 5.1 12.3 1.2 1 0 0 1 1 1 0 Presenilin RIFIN PF02009.16 EMC95257.1 - 6.7 6.5 8.6 12 5.7 8.6 1.4 1 0 0 1 1 1 0 Rifin Epimerase PF01370.21 EMC95258.1 - 8.3e-20 71.3 0.0 1.3e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMC95258.1 - 7.7e-07 28.5 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EMC95258.1 - 3.4e-06 26.7 0.0 1.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMC95258.1 - 0.00088 18.4 0.0 0.17 10.9 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMC95258.1 - 0.0019 18.1 0.0 0.0057 16.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMC95258.1 - 0.0092 16.2 0.1 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 EMC95258.1 - 0.032 14.3 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 EMC95258.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 EMC95258.1 - 0.06 12.8 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase BAH PF01426.18 EMC95259.1 - 2.7e-07 30.5 0.0 5.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 EMC95259.1 - 9.2e-05 22.6 0.6 0.012 15.9 0.1 2.4 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD PF00628.29 EMC95259.1 - 0.003 17.4 0.4 0.003 17.4 0.4 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 EMC95259.1 - 0.01 16.0 0.4 0.061 13.5 0.1 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain RhlB PF12300.8 EMC95259.1 - 0.44 10.7 3.0 4.3 7.5 0.7 2.2 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB PH PF00169.29 EMC95260.1 - 0.00017 22.0 0.0 0.0042 17.6 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 EMC95260.1 - 0.022 15.1 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain MRP_L53 PF10780.9 EMC95264.1 - 4.2e-15 55.7 0.3 7.5e-15 54.9 0.3 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF2442 PF10387.9 EMC95264.1 - 0.17 12.2 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) RTC4 PF14474.6 EMC95265.1 - 4e-30 104.5 0.0 7e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain F420H2_quin_red PF04075.14 EMC95265.1 - 0.0018 18.4 0.1 0.0075 16.4 0.2 1.9 2 0 0 2 2 2 1 F420H(2)-dependent quinone reductase Reovirus_Mu2 PF07781.11 EMC95265.1 - 0.11 10.8 0.1 0.25 9.6 0.2 1.4 2 0 0 2 2 2 0 Reovirus minor core protein Mu-2 ORC6 PF05460.13 EMC95265.1 - 4 6.6 8.8 6.6 5.9 8.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CKS PF01111.19 EMC95266.1 - 3.7e-35 120.0 2.3 4.9e-35 119.6 2.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Pyrophosphatase PF00719.19 EMC95268.1 - 2.2e-58 196.6 0.1 3e-58 196.1 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DAD PF02109.16 EMC95269.1 - 8.8e-51 170.8 3.3 1e-50 170.6 3.3 1.0 1 0 0 1 1 1 1 DAD family Arb2 PF09757.9 EMC95269.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Arb2 domain Tmemb_14 PF03647.13 EMC95270.1 - 4e-24 85.2 9.1 5.2e-24 84.8 9.1 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C FtsL PF04999.13 EMC95271.1 - 0.0015 18.4 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Cell division protein FtsL Sulfatase PF00884.23 EMC95271.1 - 0.057 12.8 0.1 0.065 12.6 0.1 1.0 1 0 0 1 1 1 0 Sulfatase Ank_2 PF12796.7 EMC95272.1 - 1e-10 42.1 0.0 3.5e-06 27.5 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EMC95272.1 - 2.8e-10 40.2 0.0 3.1e-06 27.4 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EMC95272.1 - 2.6e-09 37.4 0.3 0.11 13.1 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC95272.1 - 1.2e-07 31.4 0.1 0.0066 16.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EMC95272.1 - 1.7e-05 25.0 0.7 0.009 16.3 0.1 3.6 3 1 0 3 3 3 1 Ankyrin repeats (many copies) DUF2892 PF11127.8 EMC95272.1 - 0.065 13.3 0.2 2.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) CAP_GLY PF01302.25 EMC95273.1 - 1.3e-17 63.5 0.9 3e-17 62.4 0.9 1.6 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 EMC95273.1 - 9.4e-06 25.4 9.7 0.00061 19.6 0.8 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle TPR_MLP1_2 PF07926.12 EMC95273.1 - 0.0054 16.8 8.2 0.0054 16.8 8.2 4.5 4 1 0 4 4 4 1 TPR/MLP1/MLP2-like protein zf-CCHC PF00098.23 EMC95273.1 - 0.064 13.4 0.4 0.17 12.0 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle JIP_LZII PF16471.5 EMC95273.1 - 0.1 12.8 0.1 0.1 12.8 0.1 4.1 5 0 0 5 5 5 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 EMC95273.1 - 0.15 12.3 34.9 1.3 9.2 11.4 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GspL_C PF12693.7 EMC95273.1 - 0.17 11.7 4.6 0.071 12.9 0.8 2.2 2 0 0 2 2 2 0 GspL periplasmic domain Fez1 PF06818.15 EMC95273.1 - 0.2 12.1 28.7 1.5 9.3 8.9 3.1 1 1 3 4 4 4 0 Fez1 ABC_tran_CTD PF16326.5 EMC95273.1 - 0.89 9.9 23.7 1.5 9.1 1.7 3.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 EMC95273.1 - 1.1 9.6 17.0 0.22 11.7 1.9 3.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 EMC95273.1 - 2.2 7.1 26.7 0.79 8.5 0.1 3.7 2 1 3 5 5 5 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.18 EMC95273.1 - 2.5 8.2 6.9 2.2 8.4 0.4 3.0 1 1 1 3 3 3 0 Cobalamin adenosyltransferase ADIP PF11559.8 EMC95273.1 - 3.1 7.9 25.3 3.7 7.6 0.9 4.1 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 EMC95273.1 - 6.2 7.4 7.1 5 7.7 0.1 3.7 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein zf-CCCH PF00642.24 EMC95274.1 - 3.5e-22 77.8 33.6 1.6e-06 27.9 0.6 5.1 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EMC95274.1 - 6.5e-22 76.9 32.2 1.4e-06 28.1 4.6 5.1 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 EMC95274.1 - 3.1e-12 47.2 26.2 0.00027 21.6 0.9 4.8 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 EMC95274.1 - 4.8e-10 39.0 38.9 0.0001 22.0 1.6 5.3 5 0 0 5 5 5 5 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EMC95274.1 - 1.5e-06 28.4 8.9 0.0053 17.0 1.1 2.6 1 1 1 2 2 2 2 Zinc-finger containing family DUF1771 PF08590.10 EMC95275.1 - 2e-13 50.5 10.9 2e-13 50.5 10.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 EMC95275.1 - 1.6e-08 34.3 10.9 5e-06 26.4 1.6 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EMC95275.1 - 9.1e-08 31.8 4.7 0.00068 19.5 0.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.21 EMC95275.1 - 8.7e-07 29.2 0.0 3.2e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Smr domain zf-CCCH_4 PF18044.1 EMC95275.1 - 7.4e-06 25.6 1.0 7.4e-06 25.6 1.0 2.9 2 1 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EMC95275.1 - 1.2e-05 25.6 10.1 0.0039 17.6 1.9 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EMC95275.1 - 0.00065 19.9 2.5 0.25 11.6 0.0 2.5 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 EMC95275.1 - 0.026 15.2 4.1 0.2 12.4 0.9 2.5 1 1 1 2 2 2 0 Torus domain CUE PF02845.16 EMC95275.1 - 0.12 12.1 0.2 0.49 10.1 0.1 2.1 2 0 0 2 2 2 0 CUE domain TraB PF01963.17 EMC95275.1 - 1.5 8.7 7.5 1.3 8.8 2.0 2.8 2 1 1 3 3 3 0 TraB family Scm3 PF10384.9 EMC95277.1 - 5e-23 80.6 0.3 1.8e-22 78.8 0.3 2.1 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-binding PF00249.31 EMC95277.1 - 5.4e-18 64.9 1.0 0.011 16.0 0.0 5.0 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC95277.1 - 5.3e-16 58.6 0.2 0.0099 16.1 0.1 5.4 5 0 0 5 5 5 4 Myb-like DNA-binding domain GATA PF00320.27 EMC95277.1 - 3.5e-10 39.3 3.4 5.9e-10 38.6 3.4 1.4 1 0 0 1 1 1 1 GATA zinc finger Sigma70_r4_2 PF08281.12 EMC95277.1 - 0.00021 20.9 0.0 0.11 12.2 0.1 2.6 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_20 PF12840.7 EMC95277.1 - 0.0016 18.4 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain Myb_DNA-bind_2 PF08914.11 EMC95277.1 - 0.0021 18.2 1.4 0.21 11.8 0.3 3.7 3 1 0 3 3 3 1 Rap1 Myb domain COX4 PF02936.14 EMC95277.1 - 0.01 15.9 0.2 5.4 7.0 0.0 3.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV HTH_23 PF13384.6 EMC95277.1 - 0.016 15.0 0.0 2.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Homeodomain-like domain APG6 PF04111.12 EMC95278.1 - 9e-64 214.7 0.0 1.3e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EMC95278.1 - 1.1e-33 116.5 23.2 2.2e-33 115.6 23.2 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region LUC7 PF03194.15 EMC95278.1 - 0.0077 15.9 2.6 0.013 15.2 2.6 1.4 1 0 0 1 1 1 1 LUC7 N_terminus DUF812 PF05667.11 EMC95278.1 - 0.032 13.1 9.0 0.041 12.8 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) YabA PF06156.13 EMC95278.1 - 0.044 14.4 3.1 0.066 13.8 2.0 1.8 1 1 0 1 1 1 0 Initiation control protein YabA FUSC PF04632.12 EMC95278.1 - 0.045 12.3 6.1 0.061 11.8 6.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 EMC95278.1 - 0.16 9.9 4.4 0.22 9.4 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.9 EMC95278.1 - 0.17 12.2 11.6 0.49 10.7 11.6 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein UPF0242 PF06785.11 EMC95278.1 - 0.19 11.8 16.7 0.35 11.0 16.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 EMC95278.1 - 0.58 10.2 18.2 1.3 9.0 17.1 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EMC95278.1 - 1.1 9.3 5.5 1.2 9.1 4.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 EMC95278.1 - 2.5 8.4 9.6 0.12 12.6 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) HAUS-augmin3 PF14932.6 EMC95278.1 - 3.6 7.1 18.5 9.2 5.8 18.5 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 EMC95278.1 - 3.7 6.8 16.5 9.7 5.4 16.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 EMC95278.1 - 5.1 7.6 19.3 3.9 8.0 16.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB ERM PF00769.19 EMC95278.1 - 5.2 6.8 24.1 9.3 6.0 24.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FapA PF03961.13 EMC95278.1 - 6.3 5.3 9.4 4.4 5.8 7.7 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A adh_short PF00106.25 EMC95279.1 - 1.1e-31 109.8 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC95279.1 - 1.1e-26 93.9 0.0 1.4e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC95279.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 EMC95279.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LSM PF01423.22 EMC95280.1 - 4e-22 77.7 0.2 4.5e-22 77.5 0.2 1.0 1 0 0 1 1 1 1 LSM domain APH PF01636.23 EMC95281.1 - 4.4e-41 141.4 0.0 6.9e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EMC95281.1 - 2.4e-06 27.1 0.0 5.6e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EMC95281.1 - 3.2e-05 23.6 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EMC95281.1 - 0.056 12.8 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 EMC95281.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Methyltransf_28 PF02636.17 EMC95282.1 - 2.2e-39 135.7 0.0 3.6e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EMC95282.1 - 0.007 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PALP PF00291.25 EMC95283.1 - 9.7e-61 205.7 1.3 1.2e-60 205.4 1.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C2H2 PF00096.26 EMC95286.1 - 3.3e-10 39.8 11.4 1.3e-05 25.3 4.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC95286.1 - 1.5e-08 34.6 16.5 4.7e-05 23.6 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC95286.1 - 3.6e-07 30.4 10.4 0.00057 20.5 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EMC95286.1 - 6.4e-06 26.4 1.2 1.7e-05 25.0 1.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EMC95286.1 - 6.8e-05 22.8 8.3 0.00013 21.9 2.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMC95286.1 - 0.00074 19.7 5.0 0.00094 19.4 2.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EMC95286.1 - 0.12 12.7 2.5 0.14 12.5 1.4 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 EMC95286.1 - 0.15 12.0 5.0 3.6 7.6 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EMC95286.1 - 0.32 10.8 8.1 2.1 8.2 0.6 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EMC95286.1 - 2 8.5 5.3 0.77 9.8 0.9 2.2 2 0 0 2 2 2 0 BED zinc finger GDP_Man_Dehyd PF16363.5 EMC95287.1 - 4.4e-68 230.1 0.0 5.3e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMC95287.1 - 8.6e-55 185.8 0.0 1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC95287.1 - 1.8e-22 79.9 0.0 1.4e-21 76.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EMC95287.1 - 2.9e-17 62.6 0.0 3.8e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMC95287.1 - 1.1e-16 60.8 0.0 1.2e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EMC95287.1 - 7.9e-15 54.7 0.0 9.8e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMC95287.1 - 9.1e-05 22.4 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TPT PF03151.16 EMC95288.1 - 8e-12 45.1 12.6 1.5e-11 44.2 12.6 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EMC95288.1 - 2.1e-06 28.0 24.2 1.4e-05 25.3 9.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family RmlD_sub_bind PF04321.17 EMC95289.1 - 3.6e-14 52.5 0.0 5.2e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EMC95289.1 - 5.1e-12 45.8 0.0 7.8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC95289.1 - 5e-06 25.9 0.0 7.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMC95289.1 - 0.00022 20.8 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase WD40 PF00400.32 EMC95290.1 - 0.00082 20.1 3.8 1.3 10.0 0.0 4.1 4 1 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.15 EMC95290.1 - 0.0038 16.6 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region Vps53_N PF04100.12 EMC95291.1 - 2.1e-107 359.4 2.8 2.1e-107 359.4 2.8 2.0 3 0 0 3 3 3 1 Vps53-like, N-terminal Vps54_N PF10475.9 EMC95291.1 - 6.3e-07 29.0 6.0 1.2e-06 28.0 6.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EMC95291.1 - 0.00011 22.1 0.0 0.00029 20.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Zw10 PF06248.13 EMC95291.1 - 0.012 14.2 5.0 0.025 13.2 5.0 1.4 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF5344 PF17279.2 EMC95291.1 - 0.034 14.7 0.5 0.89 10.2 0.1 3.6 3 1 1 4 4 4 0 Family of unknown function (DUF5344) SesA PF17107.5 EMC95291.1 - 0.073 13.3 1.4 10 6.3 0.6 3.4 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Flagellin_N PF00669.20 EMC95291.1 - 0.66 10.1 6.6 0.87 9.7 0.6 2.9 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4164 PF13747.6 EMC95291.1 - 1 9.7 6.8 0.86 9.9 3.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 EMC95291.1 - 1.8 9.1 9.3 0.33 11.5 2.4 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region COG2 PF06148.11 EMC95291.1 - 6.2 6.9 10.3 0.54 10.4 1.4 3.5 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Amino_oxidase PF01593.24 EMC95292.1 - 7.6e-80 269.4 0.0 3.1e-78 264.1 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 EMC95292.1 - 2.8e-15 56.4 0.0 8.8e-15 54.8 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 EMC95292.1 - 1.8e-07 31.2 0.0 4.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 EMC95292.1 - 5.6e-07 29.9 0.2 1.3e-06 28.7 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.24 EMC95292.1 - 6.8e-05 22.6 1.1 0.00012 21.8 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase HMG_box_2 PF09011.10 EMC95292.1 - 0.00099 19.7 0.6 0.0025 18.3 0.6 1.7 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.14 EMC95292.1 - 0.0012 18.1 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC95292.1 - 0.031 14.3 0.4 3 7.8 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EMC95292.1 - 0.052 12.8 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAPDH_C PF16654.5 EMC95293.1 - 0.071 12.9 0.5 0.083 12.7 0.5 1.2 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Pyr_redox_2 PF07992.14 EMC95294.1 - 1.2e-44 152.7 0.3 1.5e-44 152.4 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC95294.1 - 1.2e-20 74.0 0.3 3.2e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC95294.1 - 7.8e-16 58.4 0.1 4.7e-14 52.7 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC95294.1 - 5.3e-06 25.9 0.1 0.0057 15.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.7 EMC95294.1 - 7.8e-06 25.5 2.6 6.7e-05 22.4 0.1 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EMC95294.1 - 2.4e-05 23.6 3.0 0.059 12.4 0.2 3.8 3 1 1 4 4 4 2 Glucose inhibited division protein A DAO PF01266.24 EMC95294.1 - 2.8e-05 23.9 1.1 1.2 8.6 0.0 3.2 2 1 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 EMC95294.1 - 0.00022 20.5 0.5 0.012 14.7 0.1 2.8 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EMC95294.1 - 0.00063 18.6 0.1 0.04 12.6 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 EMC95294.1 - 0.00096 19.3 0.2 0.13 12.5 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EMC95294.1 - 0.0024 18.3 1.6 0.076 13.5 0.1 3.3 3 1 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EMC95294.1 - 0.012 14.7 7.6 0.099 11.7 0.7 3.1 3 1 0 4 4 4 0 FAD binding domain Shikimate_DH PF01488.20 EMC95294.1 - 0.027 14.6 0.0 1.2 9.1 0.0 3.1 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 EMC95294.1 - 0.052 12.4 0.1 2.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro_17 PF00332.18 EMC95298.1 - 0.0013 18.3 0.8 0.0028 17.3 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Pro_isomerase PF00160.21 EMC95299.1 - 3.1e-50 170.5 0.2 3.4e-50 170.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_transf_22 PF03901.17 EMC95300.1 - 1.8e-32 113.1 17.4 2.1e-32 112.9 17.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MFS_1 PF07690.16 EMC95301.1 - 2.2e-44 151.9 61.3 1.6e-42 145.7 61.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC95301.1 - 1.3e-24 86.6 18.1 2e-24 85.9 18.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMC95301.1 - 7.7e-19 67.9 1.7 7.7e-19 67.9 1.7 3.9 3 1 0 4 4 4 1 Sugar (and other) transporter YobH PF13996.6 EMC95301.1 - 0.51 10.4 0.0 0.51 10.4 0.0 3.1 3 0 0 3 3 3 0 YobH-like protein SMYLE_N PF18615.1 EMC95301.1 - 1.8 8.0 7.0 0.85 9.1 0.1 2.2 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4554 PF15091.6 EMC95301.1 - 1.9 7.3 5.0 3.3 6.5 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Pex14_N PF04695.13 EMC95301.1 - 2.4 8.8 17.1 1.4 9.5 0.8 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fungal_trans PF04082.18 EMC95302.1 - 7.3e-20 71.1 0.1 1.4e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC95302.1 - 2.3e-07 30.8 12.8 5.2e-07 29.7 12.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfate_transp PF00916.20 EMC95306.1 - 6.5e-110 367.5 19.6 1e-109 366.8 19.6 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMC95306.1 - 2.7e-06 27.0 0.0 5.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EMC95306.1 - 0.00015 22.1 3.8 0.00015 22.1 3.8 2.9 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily SLATT_4 PF18186.1 EMC95306.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 YdjM PF04307.14 EMC95306.1 - 5.7 6.2 9.7 0.83 8.9 5.0 2.0 2 0 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase RabGAP-TBC PF00566.18 EMC95307.1 - 4.1e-35 121.4 0.0 1.4e-26 93.5 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain ArfA PF03889.13 EMC95307.1 - 0.19 11.2 0.1 0.5 9.9 0.0 1.7 2 0 0 2 2 2 0 Alternative ribosome-rescue factor A Sulfotransfer_4 PF17784.1 EMC95308.1 - 0.0046 16.8 0.0 0.0053 16.6 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase domain ChaC PF04752.12 EMC95311.1 - 1.9e-55 187.7 0.0 2.5e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Dynamin_N PF00350.23 EMC95312.1 - 1.3e-29 103.4 0.0 2.9e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EMC95312.1 - 1e-17 64.3 0.0 2.6e-17 62.9 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EMC95312.1 - 0.00083 19.4 0.0 0.0057 16.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_27 PF13514.6 EMC95312.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain UCH PF00443.29 EMC95315.1 - 1.7e-56 191.6 0.0 3.7e-56 190.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC95315.1 - 1.3e-28 100.6 0.6 1.8e-21 77.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EMC95315.1 - 0.00073 19.1 3.2 0.017 14.6 1.8 2.6 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Spc7 PF08317.11 EMC95315.1 - 2.8 6.8 12.5 0.24 10.2 7.5 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein EF-hand_1 PF00036.32 EMC95316.1 - 8.8e-26 87.5 7.8 1.1e-07 30.9 0.2 5.0 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EMC95316.1 - 1.2e-21 74.7 4.6 9.1e-05 22.1 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EMC95316.1 - 2.2e-19 69.0 2.4 1.3e-11 44.2 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EMC95316.1 - 1.1e-18 65.8 8.9 0.00059 19.2 0.0 4.6 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EMC95316.1 - 1.6e-18 66.9 6.8 3.7e-10 40.1 0.1 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EMC95316.1 - 0.025 14.5 0.4 1 9.4 0.0 2.6 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EMC95316.1 - 0.21 11.9 0.4 4.5 7.6 0.0 2.7 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_S13_N PF08069.12 EMC95318.1 - 3.7e-29 100.6 0.1 6.1e-29 99.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EMC95318.1 - 3.5e-15 56.0 0.2 5.1e-15 55.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EMC95318.1 - 0.022 14.7 0.1 0.047 13.6 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain LMBR1 PF04791.16 EMC95319.1 - 3.3e-18 65.9 1.7 3.3e-18 65.9 1.7 2.6 2 1 1 3 3 3 1 LMBR1-like membrane protein NfeD PF01957.18 EMC95319.1 - 0.23 11.8 2.5 18 5.8 0.0 3.4 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding CPSF_A PF03178.15 EMC95320.1 - 6.5e-78 262.3 0.0 5.9e-77 259.1 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.9 EMC95320.1 - 3.6e-22 78.7 0.0 5.9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RRM_1 PF00076.22 EMC95324.1 - 6e-21 74.0 0.0 7.7e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC95324.1 - 0.00095 19.2 0.0 0.0015 18.6 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 EMC95324.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RTC_insert PF05189.13 EMC95325.1 - 2.7e-29 101.7 0.0 5.9e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EMC95325.1 - 1e-28 100.1 0.1 1.3e-28 99.8 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Rax2 PF12768.7 EMC95326.1 - 2.4e-37 128.5 0.4 3.7e-36 124.6 0.1 3.0 3 0 0 3 3 3 1 Cortical protein marker for cell polarity Kelch_4 PF13418.6 EMC95326.1 - 2 8.5 6.6 4.8 7.3 0.0 4.4 6 0 0 6 6 6 0 Galactose oxidase, central domain WD40 PF00400.32 EMC95327.1 - 6.5e-51 169.2 13.7 8.2e-06 26.5 0.1 12.1 11 1 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC95327.1 - 2.5e-19 69.4 0.1 0.0021 18.3 0.0 8.7 5 5 5 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EMC95327.1 - 1.8e-14 53.9 0.0 3.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EMC95327.1 - 1.5e-08 34.0 0.3 1.1 8.1 0.0 6.3 4 1 4 8 8 8 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EMC95327.1 - 8e-07 28.1 0.4 0.087 11.4 0.0 4.8 5 0 0 5 5 5 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EMC95327.1 - 0.15 10.9 0.6 15 4.4 0.1 3.1 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain P34-Arc PF04045.14 EMC95328.1 - 5.5e-105 350.4 0.0 6.6e-105 350.1 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Radical_SAM PF04055.21 EMC95328.1 - 0.086 13.2 0.2 0.33 11.3 0.2 1.8 1 1 0 2 2 2 0 Radical SAM superfamily DUF5359 PF17313.2 EMC95329.1 - 0.22 11.5 0.0 0.47 10.5 0.0 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5359) TolA_bind_tri PF16331.5 EMC95330.1 - 0.12 12.4 0.4 0.17 12.0 0.4 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation PAF-AH_p_II PF03403.13 EMC95331.1 - 4.2e-39 134.2 0.0 5e-38 130.6 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EMC95331.1 - 2.1e-06 26.9 0.0 1.8e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EMC95331.1 - 2.1e-05 23.9 0.0 0.003 16.9 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMC95331.1 - 0.00021 21.9 0.1 0.00056 20.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 EMC95331.1 - 0.0042 16.1 0.0 0.0087 15.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase DUF3328 PF11807.8 EMC95332.1 - 5e-14 52.6 0.0 7.4e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Reprolysin_5 PF13688.6 EMC95333.1 - 2.7e-56 190.9 15.9 2.7e-56 190.9 15.9 3.0 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EMC95333.1 - 5.3e-46 157.0 9.5 1.4e-45 155.6 9.5 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EMC95333.1 - 5.1e-44 150.3 14.9 1.2e-43 149.1 14.9 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EMC95333.1 - 3.1e-17 63.1 30.6 3.1e-17 63.1 30.6 4.9 3 2 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EMC95333.1 - 1.7e-10 41.5 0.6 6.2e-10 39.7 0.6 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 EMC95333.1 - 0.0014 19.1 12.7 0.0014 19.1 12.7 5.4 1 1 3 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 EMC95333.1 - 0.067 13.4 0.0 0.91 9.7 0.0 2.7 3 0 0 3 3 3 0 Reprolysin family propeptide DUF2076 PF09849.9 EMC95333.1 - 0.93 9.5 9.6 1.8 8.6 9.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Creatininase PF02633.14 EMC95334.1 - 0.045 13.2 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Creatinine amidohydrolase Cupin_2 PF07883.11 EMC95335.1 - 4.4e-07 29.5 0.0 1.3e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Cupin domain CtaG_Cox11 PF04442.14 EMC95336.1 - 3.3e-58 196.0 0.0 4.2e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 zf-HIT PF04438.16 EMC95337.1 - 2e-09 37.2 12.4 3.2e-09 36.5 12.4 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EMC95337.1 - 0.046 13.8 10.9 0.094 12.8 10.9 1.5 1 0 0 1 1 1 0 MYND finger FXMRP1_C_core PF12235.8 EMC95337.1 - 0.27 11.9 9.9 0.048 14.3 5.3 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal FoP_duplication PF13865.6 EMC95337.1 - 9.3 6.9 19.3 2.2 8.9 15.4 1.8 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 RasGEF PF00617.19 EMC95338.1 - 9.1e-48 162.8 0.2 1.4e-47 162.2 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EMC95338.1 - 5.3e-12 45.9 0.0 2.3e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 EMC95338.1 - 2.1e-07 30.7 0.0 1.8e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Ras family DUF2236 PF09995.9 EMC95340.1 - 4.5e-33 115.4 0.1 5.6e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF5440 PF17509.2 EMC95340.1 - 0.039 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5440) Rxt3 PF08642.10 EMC95342.1 - 2.3e-34 118.9 0.0 5.3e-34 117.7 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EMC95342.1 - 1.7e-05 24.8 0.0 0.00013 22.0 0.0 2.1 2 0 0 2 2 2 1 LCCL domain Rgp1 PF08737.10 EMC95343.1 - 3.2e-143 477.9 0.0 5.6e-143 477.1 0.0 1.4 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.29 EMC95343.1 - 0.00012 22.1 0.0 0.00049 20.2 0.0 2.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Neugrin PF06413.11 EMC95344.1 - 3.3e-09 37.1 0.3 8.7e-09 35.7 0.3 1.7 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 EMC95344.1 - 5.1e-07 30.0 1.1 5.1e-07 30.0 1.1 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Ribonuclease_3 PF00636.26 EMC95345.1 - 1.1e-35 122.4 0.0 4.7e-19 69.0 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EMC95345.1 - 2.8e-27 95.4 0.8 4.6e-13 49.5 0.1 3.8 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EMC95345.1 - 2.2e-20 72.6 0.1 6.9e-20 71.0 0.0 1.9 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 EMC95345.1 - 3.9e-16 59.3 0.0 1e-15 57.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC95345.1 - 1.6e-13 50.9 0.0 4.6e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC95345.1 - 2.8e-12 47.0 0.0 5.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMC95345.1 - 0.1 12.9 0.0 0.36 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain RINGv PF12906.7 EMC95346.1 - 6.1e-10 39.1 3.7 2.2e-09 37.3 1.0 2.4 2 0 0 2 2 2 1 RING-variant domain ABC2_membrane_2 PF12679.7 EMC95346.1 - 0.0029 16.9 0.6 0.0043 16.4 0.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein PHD PF00628.29 EMC95346.1 - 0.024 14.5 3.2 0.024 14.5 3.2 1.7 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 EMC95346.1 - 0.037 14.4 5.8 0.13 12.6 2.1 2.2 2 0 0 2 2 2 0 Ring finger domain DUF4079 PF13301.6 EMC95346.1 - 0.12 12.5 0.9 0.26 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) PHD_4 PF16866.5 EMC95346.1 - 0.19 11.8 7.5 2.1 8.5 3.1 2.6 3 0 0 3 3 3 0 PHD-finger Proteasome PF00227.26 EMC95347.1 - 4.3e-56 189.4 0.1 8.4e-32 110.2 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EMC95347.1 - 9.5e-11 41.2 0.1 3.3e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RabGAP-TBC PF00566.18 EMC95348.1 - 3.1e-50 170.8 2.5 9.5e-49 166.0 0.3 3.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 EMC95348.1 - 0.00075 19.6 8.0 0.00075 19.6 8.0 3.4 3 1 1 4 4 4 2 Centrosomin N-terminal motif 1 HALZ PF02183.18 EMC95348.1 - 0.0061 16.8 3.0 0.0061 16.8 3.0 4.4 4 0 0 4 4 4 1 Homeobox associated leucine zipper KorB PF08535.10 EMC95348.1 - 0.12 12.4 1.0 16 5.6 0.3 2.7 2 0 0 2 2 2 0 KorB domain Seadorna_VP6 PF07407.11 EMC95348.1 - 1.6 7.6 4.7 1.5 7.7 3.5 1.5 2 0 0 2 2 2 0 Seadornavirus VP6 protein TSC22 PF01166.18 EMC95348.1 - 1.9 8.8 17.2 1.5 9.2 4.7 3.7 2 1 1 3 3 3 0 TSC-22/dip/bun family ATG16 PF08614.11 EMC95348.1 - 3.9 7.7 31.7 2.9 8.1 6.8 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EMC95348.1 - 7.1 6.7 22.3 0.71 9.9 1.3 3.4 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Acetyltransf_3 PF13302.7 EMC95349.1 - 0.002 18.8 0.1 0.0023 18.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BofC_C PF08955.10 EMC95351.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 BofC C-terminal domain Lipoprotein_8 PF02030.15 EMC95352.1 - 0.11 11.2 0.4 0.14 10.8 0.4 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) Dynein_attach_N PF15867.5 EMC95356.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Dynein attachment factor N-terminus Rhodanese PF00581.20 EMC95358.1 - 8.2e-07 29.5 0.0 1.5e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain WLM PF08325.10 EMC95359.1 - 4.1e-55 186.8 0.4 6.3e-55 186.2 0.4 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EMC95359.1 - 0.00028 20.1 18.1 0.00053 19.2 2.9 3.2 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 EMC95359.1 - 0.019 15.0 6.3 0.039 14.0 6.3 1.6 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 EMC95359.1 - 0.065 14.0 2.0 0.12 13.2 2.0 1.4 1 0 0 1 1 1 0 zinc-ribbon family Peptidase_M54 PF07998.11 EMC95359.1 - 0.25 11.3 0.0 0.43 10.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 C1_2 PF03107.16 EMC95359.1 - 1.7 9.0 5.4 25 5.3 0.2 2.8 2 0 0 2 2 2 0 C1 domain HATPase_c PF02518.26 EMC95361.1 - 3.1e-29 101.7 0.1 6.7e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMC95361.1 - 3e-22 78.9 0.0 9.6e-22 77.3 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EMC95361.1 - 1.6e-20 72.9 0.2 6.7e-20 70.9 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EMC95361.1 - 1.6e-14 53.9 0.8 4.4e-14 52.5 0.8 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMC95361.1 - 2e-11 44.1 0.1 0.063 13.5 0.0 5.1 4 0 0 4 4 4 3 PAS fold PAS PF00989.25 EMC95361.1 - 2.9e-07 30.5 0.0 0.077 13.0 0.0 3.9 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 EMC95361.1 - 1.7e-06 28.2 0.0 0.088 13.1 0.0 3.8 3 0 0 3 3 3 2 PAS domain Arm-DNA-bind_3 PF13356.6 EMC95361.1 - 0.1 13.0 0.5 3 8.3 0.1 2.9 2 0 0 2 2 2 0 Arm DNA-binding domain O-FucT PF10250.9 EMC95362.1 - 4.6e-19 69.3 0.0 9.3e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PsiA PF06952.11 EMC95362.1 - 0.043 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 PsiA protein SNARE_assoc PF09335.11 EMC95363.1 - 9.6e-13 48.7 4.9 9.6e-13 48.7 4.9 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein LapA_dom PF06305.11 EMC95363.1 - 0.95 9.3 0.0 0.95 9.3 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ETRAMP PF09716.10 EMC95363.1 - 1.3 9.1 4.5 5.6 7.1 0.2 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3552 PF12072.8 EMC95363.1 - 4.6 6.6 5.1 2.4 7.5 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF2401 PF10287.9 EMC95364.1 - 9.1e-87 290.4 0.0 1.7e-86 289.5 0.0 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EMC95364.1 - 6.3e-27 93.8 0.1 1.4e-26 92.7 0.1 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SelP_N PF04592.14 EMC95364.1 - 0.11 11.9 1.4 0.17 11.2 1.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SWI-SNF_Ssr4 PF08549.10 EMC95364.1 - 0.26 9.9 1.9 0.34 9.5 1.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Macoilin PF09726.9 EMC95364.1 - 0.41 9.2 3.1 0.5 8.9 3.1 1.1 1 0 0 1 1 1 0 Macoilin family CCDC24 PF15669.5 EMC95364.1 - 0.65 9.8 2.4 1.1 9.0 2.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family RAP1 PF07218.11 EMC95364.1 - 4 5.6 9.3 5.3 5.2 9.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peroxin-13_N PF04088.13 EMC95366.1 - 5e-53 179.3 0.2 8.9e-53 178.5 0.2 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EMC95366.1 - 1.6e-09 37.3 0.0 2.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMC95366.1 - 1.6e-06 27.6 0.3 9e-06 25.2 0.3 2.1 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMC95366.1 - 7.1e-05 22.6 0.1 0.00018 21.3 0.1 1.7 1 1 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.14 EMC95366.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region hSH3 PF14603.6 EMC95366.1 - 0.084 13.3 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Dpy-30 PF05186.13 EMC95368.1 - 2.6e-13 49.4 0.7 4.8e-13 48.6 0.2 1.6 2 0 0 2 2 2 1 Dpy-30 motif VHP PF02209.19 EMC95369.1 - 0.21 11.7 0.7 0.36 10.9 0.7 1.4 1 0 0 1 1 1 0 Villin headpiece domain DUF1427 PF07235.11 EMC95370.1 - 0.034 14.1 3.1 0.056 13.4 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) DUF1129 PF06570.11 EMC95370.1 - 0.044 13.3 2.8 0.25 10.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Ost5 PF05251.12 EMC95370.1 - 0.046 14.0 0.1 0.046 14.0 0.1 2.5 3 1 0 3 3 3 0 Oligosaccharyltransferase subunit 5 Phage_holin_5_2 PF16079.5 EMC95370.1 - 0.12 12.7 3.2 2.7 8.4 1.5 2.8 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF4191 PF13829.6 EMC95370.1 - 0.14 11.4 4.9 0.17 11.2 3.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) TctB PF07331.11 EMC95370.1 - 0.17 12.1 11.8 0.056 13.7 6.5 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family AzlD PF05437.12 EMC95370.1 - 0.27 11.4 6.4 1.1 9.4 3.5 2.6 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) PA26 PF04636.13 EMC95371.1 - 0.051 12.5 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TAP_C PF03943.13 EMC95373.1 - 4.4e-16 58.2 0.5 9.6e-16 57.2 0.2 1.7 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.7 EMC95373.1 - 2.7e-05 24.4 3.5 0.001 19.4 2.8 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EMC95373.1 - 0.00022 20.8 0.2 0.00041 19.9 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EMC95373.1 - 0.00027 20.6 1.8 0.00064 19.4 1.8 1.7 1 0 0 1 1 1 1 Leucine rich repeat RRM_9 PF18444.1 EMC95373.1 - 0.00085 19.1 0.0 0.0054 16.5 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif UBA_4 PF14555.6 EMC95373.1 - 0.012 15.4 0.1 0.048 13.5 0.1 2.1 1 0 0 1 1 1 0 UBA-like domain NTF2 PF02136.20 EMC95373.1 - 0.028 15.0 0.0 0.1 13.1 0.0 2.0 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Ribosomal_S5_C PF03719.15 EMC95373.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain SF3b1 PF08920.10 EMC95374.1 - 2e-28 99.2 0.7 2e-28 99.2 0.7 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EMC95374.1 - 2.2e-10 40.8 2.3 0.11 13.1 0.0 6.7 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 EMC95374.1 - 3.5e-10 40.1 4.6 0.2 12.0 0.1 8.1 4 3 5 10 10 10 2 HEAT repeats HEAT PF02985.22 EMC95374.1 - 1.4e-09 37.4 8.1 0.071 13.4 0.1 9.1 10 0 0 10 10 10 1 HEAT repeat Cnd1 PF12717.7 EMC95374.1 - 2.1e-09 37.6 0.1 0.071 13.1 0.0 6.4 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EMC95374.1 - 1.4e-05 23.9 0.3 0.0067 15.0 0.1 3.3 3 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 EMC95374.1 - 7e-05 22.6 0.3 1.1 8.9 0.0 4.7 3 1 2 5 5 5 1 NUC173 domain Vac14_Fab1_bd PF12755.7 EMC95374.1 - 0.00014 22.4 0.1 4.6 7.9 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EMC95374.1 - 0.00033 20.6 1.0 0.049 13.5 0.0 4.5 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) UNC45-central PF11701.8 EMC95374.1 - 0.00072 19.5 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 EMC95374.1 - 0.0022 17.6 0.2 0.93 9.0 0.0 3.5 3 0 0 3 3 3 1 CLASP N terminal DRIM PF07539.12 EMC95374.1 - 0.062 11.6 0.0 6.2 5.0 0.0 3.3 2 1 1 3 3 3 0 Down-regulated in metastasis Acetyltransf_1 PF00583.25 EMC95375.1 - 1.8e-10 41.1 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC95375.1 - 1.5e-09 38.1 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC95375.1 - 2.1e-09 37.4 0.0 2.5e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC95375.1 - 3.1e-05 23.8 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EMC95375.1 - 0.0027 17.8 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Sugar_tr PF00083.24 EMC95376.1 - 2.9e-124 415.4 27.0 3.4e-124 415.2 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC95376.1 - 1.8e-24 86.3 64.7 8.2e-22 77.6 33.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4407 PF14362.6 EMC95377.1 - 0.27 10.5 11.2 0.37 10.1 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C4H2 PF10146.9 EMC95377.1 - 5.9 7.1 18.6 8.8 6.6 18.6 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Peptidase_M20 PF01546.28 EMC95379.1 - 1.5e-34 119.6 0.2 2.2e-34 119.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMC95379.1 - 3.2e-12 46.3 0.0 6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EMC95379.1 - 0.00094 18.9 0.0 0.0039 16.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 PWI PF01480.17 EMC95383.1 - 6.5e-25 87.3 0.0 9.4e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 PWI domain Pro_isomerase PF00160.21 EMC95384.1 - 1.5e-53 181.3 0.0 2.3e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_25 PF13649.6 EMC95385.1 - 1.8e-18 67.0 0.1 2.1e-17 63.6 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC95385.1 - 2.8e-16 59.9 0.1 7.4e-16 58.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC95385.1 - 5.7e-16 58.7 0.0 8.9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC95385.1 - 5.2e-15 56.0 0.1 8.1e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC95385.1 - 4.3e-13 49.1 0.0 6.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EMC95385.1 - 2e-07 31.0 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMC95385.1 - 3.7e-07 29.7 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EMC95385.1 - 4e-07 30.0 0.0 9.4e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EMC95385.1 - 6.2e-06 25.7 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EMC95385.1 - 7.6e-06 26.0 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EMC95385.1 - 1.7e-05 23.9 0.0 3.5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 EMC95385.1 - 7.6e-05 22.2 0.0 0.00015 21.3 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase RrnaAD PF00398.20 EMC95385.1 - 0.00012 21.2 0.0 0.00017 20.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 EMC95385.1 - 0.00015 21.5 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 EMC95385.1 - 0.0014 18.6 0.2 0.0022 17.9 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMC95385.1 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EMC95385.1 - 0.0023 17.6 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DOT1 PF08123.13 EMC95385.1 - 0.0033 17.0 0.8 0.0039 16.7 0.0 1.4 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltr_RsmB-F PF01189.17 EMC95385.1 - 0.0052 16.4 0.1 0.011 15.4 0.1 1.6 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_5 PF01795.19 EMC95385.1 - 0.017 14.7 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 MraW methylase family DREV PF05219.12 EMC95385.1 - 0.18 10.8 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase cobW PF02492.19 EMC95386.1 - 6.5e-32 110.5 0.0 8e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EMC95386.1 - 4.7e-06 25.8 0.9 3.8e-05 22.8 0.9 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EMC95386.1 - 0.0021 18.6 0.0 0.0026 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMC95386.1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ResIII PF04851.15 EMC95386.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EMC95386.1 - 0.13 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain TMEM51 PF15345.6 EMC95386.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 SNF2_N PF00176.23 EMC95387.1 - 6.1e-38 130.4 0.0 3.7e-35 121.3 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC95387.1 - 1.1e-05 25.7 0.0 2.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC95387.1 - 0.0042 17.1 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit GAS2 PF02187.17 EMC95388.1 - 1.4e-06 28.3 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Striatin PF08232.12 EMC95388.1 - 0.11 13.1 1.8 0.52 10.9 1.8 2.2 1 0 0 1 1 1 0 Striatin family Presenilin PF01080.17 EMC95389.1 - 0.9 8.2 2.6 0.85 8.3 2.6 1.0 1 0 0 1 1 1 0 Presenilin DUF3043 PF11241.8 EMC95389.1 - 3.3 7.7 10.0 4.5 7.3 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Macoilin PF09726.9 EMC95391.1 - 4.5 5.7 10.1 4.7 5.6 10.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF5329 PF17263.2 EMC95392.1 - 0.031 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5329) DUF2470 PF10615.9 EMC95393.1 - 3.8e-22 78.7 0.2 6.9e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) HMG_box PF00505.19 EMC95394.1 - 4.3e-20 71.9 0.4 8.1e-20 71.0 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMC95394.1 - 5.7e-05 23.6 0.1 0.00012 22.6 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain 6PF2K PF01591.18 EMC95396.1 - 2.1e-79 266.0 0.1 2.7e-79 265.6 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EMC95396.1 - 4.1e-36 124.5 0.0 8.9e-36 123.4 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EMC95396.1 - 0.00014 22.1 0.1 0.00034 20.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMC95396.1 - 0.0079 15.7 0.0 0.019 14.4 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF4248 PF14053.6 EMC95396.1 - 0.072 13.1 0.0 0.94 9.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF816 PF05674.12 EMC95396.1 - 0.21 11.5 0.6 0.37 10.7 0.6 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) 2-Hacid_dh_C PF02826.19 EMC95397.1 - 1.3e-42 145.2 0.8 7.8e-28 97.0 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EMC95397.1 - 0.035 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh PF00389.30 EMC95397.1 - 0.047 13.4 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Dus PF01207.17 EMC95398.1 - 1.8e-48 165.2 0.0 9.2e-48 162.9 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 EMC95398.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase IFRD_C PF04836.12 EMC95398.1 - 0.19 12.4 0.2 0.39 11.3 0.2 1.4 1 0 0 1 1 1 0 Interferon-related protein conserved region zf-HC5HC2H_2 PF13832.6 EMC95400.1 - 1.2e-18 67.2 1.5 1.2e-18 67.2 1.5 3.8 3 1 0 3 3 3 2 PHD-zinc-finger like domain BAH PF01426.18 EMC95400.1 - 4.4e-16 58.8 0.1 1.2e-15 57.4 0.1 1.7 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 EMC95400.1 - 5.1e-15 55.5 2.7 5.1e-15 55.5 2.7 4.5 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD PF00628.29 EMC95400.1 - 2.9e-11 43.1 52.3 1.5e-06 27.9 9.6 6.0 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.6 EMC95400.1 - 7.9e-05 22.1 4.4 7.9e-05 22.1 4.4 5.3 6 0 0 6 6 6 2 PHD-finger PHD_4 PF16866.5 EMC95400.1 - 0.056 13.5 32.2 0.28 11.3 4.7 5.2 5 0 0 5 5 5 0 PHD-finger RecR PF02132.15 EMC95400.1 - 0.75 9.4 20.1 0.43 10.2 3.7 4.2 4 0 0 4 4 4 0 RecR protein IQ PF00612.27 EMC95401.1 - 0.00024 20.6 0.9 0.00024 20.6 0.9 1.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF3659 PF12396.8 EMC95402.1 - 1.1e-280 906.0 171.5 2.4e-22 78.6 3.6 15.3 15 0 0 15 15 15 14 Protein of unknown function (DUF3659) NPHI_C PF08469.10 EMC95402.1 - 0.086 12.8 0.6 16 5.4 0.0 4.5 4 0 0 4 4 4 0 Nucleoside triphosphatase I C-terminal RPW8 PF05659.11 EMC95402.1 - 0.34 10.6 0.9 1.4 8.6 0.3 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Clavanin PF05452.11 EMC95402.1 - 0.68 10.2 3.2 35 4.7 0.1 4.4 3 0 0 3 3 3 0 Clavanin F-box-like PF12937.7 EMC95403.1 - 0.0024 17.7 0.0 0.017 15.0 0.0 2.5 1 1 0 1 1 1 1 F-box-like Glyco_transf_90 PF05686.12 EMC95404.1 - 4.3e-12 45.7 0.3 1.1e-08 34.4 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 PhoLip_ATPase_C PF16212.5 EMC95404.1 - 0.23 11.2 9.8 0.45 10.2 9.8 1.5 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal tRNA-synt_2d PF01409.20 EMC95405.1 - 1.3e-42 145.9 0.1 9.3e-23 81.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EMC95405.1 - 9.7e-24 83.6 0.0 3.8e-23 81.7 0.0 2.1 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF1263 PF06882.12 EMC95405.1 - 0.51 10.4 2.0 2.8 8.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1263) Rib_recp_KP_reg PF05104.12 EMC95405.1 - 9.8 7.2 6.4 0.58 11.2 1.2 1.5 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Mito_carr PF00153.27 EMC95406.1 - 1.9e-57 191.2 0.4 8e-21 73.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NAGLU PF05089.12 EMC95408.1 - 5.5e-135 449.6 10.3 1.1e-134 448.7 10.3 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 EMC95408.1 - 4.3e-65 219.9 5.2 6.7e-65 219.3 5.2 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 EMC95408.1 - 4.5e-23 80.8 0.1 1.5e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Abhydrolase_3 PF07859.13 EMC95409.1 - 7e-31 107.7 0.0 2e-21 76.9 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold MFS_1 PF07690.16 EMC95411.1 - 1.4e-38 132.8 29.5 2.1e-38 132.2 29.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4064 PF13273.6 EMC95411.1 - 0.081 13.2 0.1 0.081 13.2 0.1 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF4064) Glyco_hydro_38N PF01074.22 EMC95413.1 - 1.5e-83 280.5 0.9 2.8e-83 279.6 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EMC95413.1 - 2.2e-58 197.9 0.1 1.4e-57 195.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EMC95413.1 - 7.9e-26 90.1 0.0 1.9e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EMC95413.1 - 2.1e-05 24.6 0.0 5.7e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Peptidase_S9 PF00326.21 EMC95414.1 - 4.1e-48 163.7 0.0 1.3e-47 162.1 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EMC95414.1 - 0.0038 16.9 0.7 0.0068 16.1 0.7 1.3 1 0 0 1 1 1 1 Putative esterase DUF2920 PF11144.8 EMC95414.1 - 0.039 13.1 0.0 0.98 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Phage_holin_5_1 PF06946.11 EMC95416.1 - 9.7 6.6 6.9 8 6.9 1.7 2.9 2 1 1 3 3 3 0 Bacteriophage A118-like holin, Hol118 Dynactin PF12455.8 EMC95417.1 - 3.5e-99 331.7 5.5 3.5e-99 331.7 5.5 3.7 4 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 EMC95417.1 - 5.8e-22 77.5 0.1 1e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 EMC95417.1 - 0.00065 19.2 28.5 0.00065 19.2 28.5 3.9 2 1 2 4 4 4 1 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.11 EMC95417.1 - 0.005 17.1 20.5 0.005 17.1 20.5 6.6 5 2 1 7 7 7 1 Autophagy protein 16 (ATG16) LIP PF03583.14 EMC95418.1 - 2.7e-57 194.3 0.1 3.9e-57 193.7 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.7 EMC95418.1 - 0.00096 19.8 0.6 0.0035 18.0 0.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EMC95418.1 - 0.0095 15.5 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EMC95418.1 - 0.1 12.2 0.0 0.73 9.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC95418.1 - 0.13 11.7 0.5 7.9 5.9 0.0 2.8 2 1 1 3 3 3 0 Prolyl oligopeptidase family NUC173 PF08161.12 EMC95419.1 - 3.2e-79 265.3 0.2 1.3e-75 253.6 0.0 2.8 2 0 0 2 2 2 2 NUC173 domain MMS19_C PF12460.8 EMC95419.1 - 0.021 14.0 16.2 0.029 13.5 1.6 4.7 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal HEAT PF02985.22 EMC95419.1 - 0.038 14.2 0.2 3.9 8.0 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat BTG PF07742.12 EMC95419.1 - 0.11 12.3 0.1 17 5.3 0.0 3.9 4 0 0 4 4 4 0 BTG family SLT PF01464.20 EMC95420.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 2 0 0 2 2 2 0 Transglycosylase SLT domain DUF2183 PF09949.9 EMC95422.1 - 1.1e-31 109.1 0.0 4.1e-31 107.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EMC95422.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Cu-oxidase_2 PF07731.14 EMC95423.1 - 6.4e-35 119.9 4.2 5.9e-33 113.5 0.2 2.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMC95423.1 - 2.8e-27 95.1 7.7 4.6e-18 65.3 0.7 3.3 3 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EMC95423.1 - 5e-24 85.2 0.6 1.6e-23 83.6 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase HET PF06985.11 EMC95424.1 - 1.5e-32 113.0 0.0 1.7e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNA_pol_A_bac PF01000.26 EMC95425.1 - 2.5e-24 85.8 0.0 2.5e-23 82.6 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EMC95425.1 - 1.6e-18 65.9 0.0 2.3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 EMC95426.1 - 7.6e-124 412.2 0.0 1e-123 411.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EMC95426.1 - 0.0035 16.3 0.0 0.0061 15.5 0.0 1.4 1 1 0 1 1 1 1 Nickel-dependent hydrogenase MTBP_C PF14920.6 EMC95427.1 - 0.032 14.0 0.2 0.043 13.6 0.2 1.2 1 0 0 1 1 1 0 MDM2-binding VanW PF04294.13 EMC95427.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 VanW like protein NmrA PF05368.13 EMC95429.1 - 2.7e-21 76.2 0.0 5.4e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC95429.1 - 5.1e-07 29.8 0.0 7.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC95429.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMC95429.1 - 0.03 14.6 0.0 0.093 13.0 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Dynamitin PF04912.14 EMC95430.1 - 4.1e-54 184.4 4.9 1.2e-38 133.4 4.3 2.0 2 0 0 2 2 2 2 Dynamitin Rx_N PF18052.1 EMC95430.1 - 0.016 15.5 1.0 0.016 15.5 1.0 2.9 3 0 0 3 3 3 0 Rx N-terminal domain DUF724 PF05266.14 EMC95430.1 - 0.2 11.5 5.2 0.13 12.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DivIC PF04977.15 EMC95430.1 - 0.57 10.0 9.3 0.075 12.8 0.6 2.8 3 0 0 3 3 3 0 Septum formation initiator Prefoldin_2 PF01920.20 EMC95430.1 - 1.9 8.5 8.2 1.1 9.3 0.8 2.8 2 0 0 2 2 2 0 Prefoldin subunit Remorin_C PF03763.13 EMC95430.1 - 2.1 8.2 11.5 0.61 10.0 1.1 3.2 3 0 0 3 3 3 0 Remorin, C-terminal region Laminin_II PF06009.12 EMC95430.1 - 5.1 7.1 8.9 2.6 8.1 0.1 3.1 3 0 0 3 3 3 0 Laminin Domain II DUF4140 PF13600.6 EMC95430.1 - 6.7 7.2 14.6 5.8 7.4 1.2 3.9 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) SRF-TF PF00319.18 EMC95431.1 - 6.8e-21 73.5 0.2 1e-20 72.9 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) tRNA-synt_1 PF00133.22 EMC95433.1 - 1.4e-215 717.2 0.1 5e-214 712.0 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMC95433.1 - 7.2e-35 120.2 0.0 1.7e-34 118.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMC95433.1 - 5.5e-15 55.0 0.4 8.2e-07 28.1 0.0 4.8 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EMC95433.1 - 8.7e-10 38.4 0.0 2.3e-06 27.3 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EMC95433.1 - 0.0017 17.8 0.0 0.07 12.5 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain PepSY PF03413.19 EMC95433.1 - 0.056 14.0 1.3 0.16 12.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Pkinase PF00069.25 EMC95435.1 - 6.5e-65 219.1 0.3 7.6e-65 218.9 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC95435.1 - 1.4e-18 67.1 0.0 2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMC95435.1 - 6.1e-07 29.6 0.0 1.5e-05 25.0 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMC95435.1 - 0.0047 15.8 0.0 0.0088 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMC95435.1 - 0.0052 16.1 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMC95435.1 - 0.017 14.5 0.1 0.033 13.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EMC95435.1 - 0.035 13.7 0.2 0.035 13.7 0.2 2.1 3 0 0 3 3 3 0 Choline/ethanolamine kinase DHHC PF01529.20 EMC95436.1 - 1e-28 100.1 9.1 1e-28 100.1 9.1 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase 3-HAO PF06052.12 EMC95437.1 - 2.5e-56 189.5 0.0 3.1e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase DZR PF12773.7 EMC95437.1 - 0.00017 21.5 1.7 0.00026 20.9 1.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon Cupin_2 PF07883.11 EMC95437.1 - 0.00075 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EMC95437.1 - 0.012 15.5 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Nudix_N_2 PF14803.6 EMC95437.1 - 0.022 14.7 1.9 1.5 8.8 0.2 2.6 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_15 PF17032.5 EMC95437.1 - 0.028 15.2 0.4 1.4 9.7 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon family TF_Zn_Ribbon PF08271.12 EMC95437.1 - 0.04 13.4 1.2 5 6.7 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding FYVE PF01363.21 EMC95437.1 - 0.079 13.1 3.7 0.17 12.1 3.7 1.5 1 1 0 1 1 1 0 FYVE zinc finger HalOD2 PF18547.1 EMC95437.1 - 0.083 12.8 1.0 3.4 7.6 0.2 2.4 2 0 0 2 2 2 0 Halobacterial output domain 2 zinc_ribbon_10 PF10058.9 EMC95437.1 - 0.091 12.5 0.2 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF35_N PF12172.8 EMC95437.1 - 0.17 11.8 4.2 5.3 7.0 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ACC PF17848.1 EMC95437.1 - 0.17 12.0 1.6 7.3 6.8 0.1 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain ADK_lid PF05191.14 EMC95437.1 - 0.67 10.0 5.0 2.3 8.3 4.5 2.1 1 1 1 2 2 2 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 EMC95437.1 - 0.7 10.1 4.7 16 5.8 4.6 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 EMC95437.1 - 1.2 8.9 5.0 19 5.1 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EMC95437.1 - 1.5 8.8 4.1 4.9 7.1 0.4 2.4 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Nop14 PF04147.12 EMC95439.1 - 2.9e-226 753.7 28.2 1.2e-178 596.2 15.0 2.1 1 1 1 2 2 2 2 Nop14-like family Metallophos PF00149.28 EMC95441.1 - 1.4e-08 35.5 0.0 0.0021 18.6 0.0 2.9 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase DUF4908 PF16252.5 EMC95443.1 - 0.087 12.3 1.7 0.12 11.9 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) DpnI PF06044.12 EMC95444.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Dam-replacing family Pkinase PF00069.25 EMC95445.1 - 7.3e-37 127.2 0.0 9.5e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMC95445.1 - 1.8e-17 63.5 0.0 7.1e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMC95445.1 - 1.2e-05 25.4 0.1 2.4e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RL10P_insert PF17777.1 EMC95446.1 - 8.8e-23 80.1 0.1 1.8e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EMC95446.1 - 1.5e-22 79.6 0.1 3e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 EMC95446.1 - 9.5e-19 67.8 7.0 9.5e-19 67.8 7.0 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein FR47 PF08445.10 EMC95447.1 - 7.9e-06 25.8 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EMC95447.1 - 0.0017 18.6 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC95447.1 - 0.11 12.9 0.0 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DJ-1_PfpI PF01965.24 EMC95448.1 - 1.3e-09 38.0 0.0 4.9e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EMC95448.1 - 0.0057 16.4 0.0 0.0074 16.0 0.0 1.4 1 1 0 1 1 1 1 ThiJ/PfpI family-like YfkB PF08756.10 EMC95448.1 - 0.21 11.4 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 YfkB-like domain ThiF PF00899.21 EMC95449.1 - 6.2e-67 225.5 0.0 8.7e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EMC95449.1 - 8e-25 86.8 0.1 1.4e-24 86.1 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EMC95449.1 - 0.0017 18.4 0.1 0.0049 16.9 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EMC95449.1 - 0.14 12.4 0.0 2.7 8.3 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain PglD_N PF17836.1 EMC95449.1 - 0.14 12.8 0.1 0.49 11.1 0.1 1.9 1 0 0 1 1 1 0 PglD N-terminal domain KR PF08659.10 EMC95449.1 - 0.15 12.0 0.0 18 5.2 0.0 2.2 2 0 0 2 2 2 0 KR domain DUF4578 PF15147.6 EMC95449.1 - 0.17 12.7 0.0 0.28 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) UBA_e1_thiolCys PF10585.9 EMC95449.1 - 0.52 10.2 2.0 12 5.7 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Telomere_reg-2 PF10193.9 EMC95450.1 - 3.7e-31 107.8 0.0 1.3e-30 106.0 0.0 2.1 1 0 0 1 1 1 1 Telomere length regulation protein CAP_N PF01213.19 EMC95450.1 - 0.049 13.1 1.3 2.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal T3SS_needle_E PF08988.10 EMC95450.1 - 0.48 10.6 3.5 5.7 7.2 0.9 3.1 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Hexokinase_2 PF03727.16 EMC95452.1 - 1.6e-73 247.1 0.0 1.9e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EMC95452.1 - 3e-50 170.9 0.0 4.1e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase SNAP PF14938.6 EMC95454.1 - 4.2e-116 387.3 16.5 4.7e-116 387.1 16.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 EMC95454.1 - 0.0016 18.3 12.4 0.95 9.6 0.1 6.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMC95454.1 - 0.0029 17.8 15.7 0.041 14.2 3.8 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat Spatacsin_C PF14649.6 EMC95454.1 - 0.04 13.0 9.9 0.44 9.6 0.1 3.0 1 1 1 2 2 2 0 Spatacsin C-terminus SMBP PF16785.5 EMC95454.1 - 0.054 13.7 2.1 0.12 12.6 1.2 2.1 2 0 0 2 2 2 0 Small metal-binding protein UVR PF02151.19 EMC95454.1 - 0.68 9.8 8.5 4.8 7.1 0.1 4.4 4 0 0 4 4 4 0 UvrB/uvrC motif TPR_2 PF07719.17 EMC95454.1 - 0.99 9.7 21.8 1.9 8.8 0.1 6.6 4 1 4 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMC95454.1 - 1.8 9.0 16.6 22 5.6 1.2 5.6 4 1 2 6 6 6 0 Tetratricopeptide repeat Mus7 PF09462.10 EMC95455.1 - 9.2e-126 421.2 0.0 1.6e-125 420.4 0.0 1.4 1 0 0 1 1 1 1 Mus7/MMS22 family Tetraspanin PF00335.20 EMC95456.1 - 5.6e-06 26.2 0.2 9.2e-06 25.5 0.2 1.5 1 1 0 1 1 1 1 Tetraspanin family BCDHK_Adom3 PF10436.9 EMC95457.1 - 3.9e-74 247.9 0.0 5.6e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EMC95457.1 - 7.1e-13 49.0 0.0 1.4e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YopE_N PF09020.10 EMC95457.1 - 0.077 13.2 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 YopE, N terminal TraT PF05818.12 EMC95458.1 - 0.14 11.8 6.0 0.29 10.8 6.0 1.5 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Sugar_tr PF00083.24 EMC95461.1 - 9.1e-76 255.5 30.8 1.1e-75 255.3 30.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC95461.1 - 3.2e-26 92.1 50.9 4.1e-25 88.4 31.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glu-tRNAGln PF02686.15 EMC95463.1 - 8.6e-10 38.8 0.0 2.3e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit MFS_1 PF07690.16 EMC95464.1 - 1.4e-54 185.4 24.3 1.4e-54 185.4 24.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC95464.1 - 1.3e-15 57.2 10.1 1.3e-15 57.2 10.1 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EMC95464.1 - 0.031 12.6 5.5 0.0097 14.2 1.2 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family UL42 PF17638.2 EMC95464.1 - 0.056 13.4 4.1 1.8 8.6 0.4 2.5 2 0 0 2 2 2 0 HCMV UL42 Zn-ribbon_8 PF09723.10 EMC95465.1 - 7.1e-05 22.8 0.6 0.00014 21.9 0.6 1.6 1 0 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 EMC95465.1 - 0.01 15.9 0.1 0.012 15.7 0.1 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CSL PF05207.13 EMC95465.1 - 0.035 13.8 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 CSL zinc finger Prok-RING_1 PF14446.6 EMC95465.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HHH_8 PF14716.6 EMC95465.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain zf-C2H2 PF00096.26 EMC95465.1 - 0.3 11.6 0.5 0.3 11.6 0.5 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC95465.1 - 0.34 11.9 2.4 3.4 8.8 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 EMC95465.1 - 1.6 8.4 3.9 0.43 10.2 0.3 1.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 EMC95465.1 - 6.1 6.7 6.7 27 4.7 1.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain NUDIX PF00293.28 EMC95467.1 - 3.4e-08 33.6 0.0 7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Rubella_E2 PF05749.11 EMC95467.1 - 0.2 11.1 4.5 0.36 10.3 4.5 1.3 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 LETM1 PF07766.13 EMC95468.1 - 1.2e-103 346.2 0.3 1.2e-103 346.2 0.3 1.8 3 0 0 3 3 3 1 LETM1-like protein SAP PF02037.27 EMC95468.1 - 7.8e-07 28.7 0.0 0.00046 19.9 0.0 3.5 3 0 0 3 3 3 1 SAP domain DUF3614 PF12267.8 EMC95468.1 - 3.7 8.0 5.1 1.5 9.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) ADK PF00406.22 EMC95469.1 - 8e-34 116.9 0.0 7.9e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EMC95469.1 - 6.2e-16 58.1 0.0 1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EMC95469.1 - 7.8e-14 52.3 0.0 3e-10 40.6 0.0 2.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EMC95469.1 - 0.045 14.3 0.0 0.69 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMC95469.1 - 0.087 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMC95469.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMC95469.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain BTB PF00651.31 EMC95470.1 - 8.4e-09 35.6 0.0 1.8e-08 34.5 0.0 1.6 1 1 1 2 2 2 1 BTB/POZ domain zinc_ribbon_4 PF13717.6 EMC95470.1 - 0.0079 16.1 0.3 2.7 8.0 0.1 2.7 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EMC95470.1 - 0.024 14.1 0.2 0.063 12.8 0.2 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 EMC95470.1 - 0.049 14.0 0.7 0.11 12.8 0.7 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ribosomal_L37ae PF01780.19 EMC95470.1 - 0.08 13.0 1.5 0.18 11.9 1.5 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family Auto_anti-p27 PF06677.12 EMC95470.1 - 0.11 12.7 0.7 0.24 11.6 0.7 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 EMC95470.1 - 0.97 8.9 3.5 17 5.0 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-HIT PF04438.16 EMC95470.1 - 1.6 8.6 5.9 0.43 10.5 1.6 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-H2C2_2 PF13465.6 EMC95470.1 - 1.9 9.1 6.1 0.3 11.6 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-H2C2_2 PF13465.6 EMC95471.1 - 0.18 12.3 1.1 0.45 11.0 1.1 1.6 1 0 0 1 1 1 0 Zinc-finger double domain Bromodomain PF00439.25 EMC95472.1 - 1.1e-31 108.7 0.1 9.8e-16 57.6 0.4 3.0 2 1 1 3 3 3 2 Bromodomain zf-RING_2 PF13639.6 EMC95474.1 - 1.9e-12 47.3 5.4 2.8e-12 46.7 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EMC95474.1 - 4.6e-09 35.9 0.3 7.8e-09 35.1 0.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EMC95474.1 - 8.3e-09 35.2 2.8 1.3e-08 34.6 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC95474.1 - 1.1e-08 34.7 5.4 1.7e-08 34.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC95474.1 - 1.5e-06 28.0 2.8 2.3e-06 27.4 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EMC95474.1 - 3.9e-06 27.1 8.5 1.9e-05 24.9 8.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EMC95474.1 - 0.00019 21.4 0.7 0.00019 21.4 0.7 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EMC95474.1 - 0.00097 19.0 2.0 0.0016 18.2 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EMC95474.1 - 0.0025 17.8 2.5 0.0068 16.4 2.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 EMC95474.1 - 0.029 14.3 5.3 0.05 13.5 5.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EMC95474.1 - 0.084 12.7 6.0 0.14 12.0 6.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EMC95474.1 - 0.12 12.3 4.3 0.22 11.4 4.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EMC95474.1 - 0.29 11.3 3.8 0.58 10.4 3.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 EMC95474.1 - 0.34 11.1 2.5 0.67 10.1 2.5 1.5 1 1 0 1 1 1 0 RING-variant domain OAD_gamma PF04277.13 EMC95474.1 - 0.38 11.4 0.0 0.38 11.4 0.0 2.7 3 1 0 3 3 2 0 Oxaloacetate decarboxylase, gamma chain Zn_ribbon_17 PF17120.5 EMC95474.1 - 0.48 10.1 4.1 0.84 9.3 4.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EMC95474.1 - 1 9.6 3.3 2.7 8.2 3.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 EMC95474.1 - 2.2 8.3 8.7 0.076 13.0 1.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CPSase_L_D2 PF02786.17 EMC95476.1 - 4.5e-106 353.1 0.0 2.8e-81 272.0 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EMC95476.1 - 4.1e-41 140.1 0.1 1.3e-40 138.5 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EMC95476.1 - 3.2e-17 62.6 0.0 1.3e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EMC95476.1 - 9.5e-15 54.7 0.1 2.8e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EMC95476.1 - 9.8e-12 44.8 0.0 1.4e-05 24.8 0.0 3.0 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 EMC95476.1 - 4.5e-06 26.6 0.0 0.048 13.4 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EMC95476.1 - 2.8e-05 23.8 0.0 0.014 15.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EMC95476.1 - 6.7e-05 23.0 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 EMC95476.1 - 8.9e-05 22.0 0.1 0.025 14.0 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain MCPsignal PF00015.21 EMC95476.1 - 0.044 13.6 0.2 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Peptidase_M17_N PF02789.17 EMC95476.1 - 0.1 12.5 0.4 0.26 11.2 0.4 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DUF5333 PF17267.2 EMC95476.1 - 0.13 12.4 0.0 0.89 9.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5333) CDP-OH_P_transf PF01066.21 EMC95477.1 - 2e-16 60.5 0.1 2e-16 60.5 0.1 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Sugar_tr PF00083.24 EMC95479.1 - 2.1e-114 382.9 24.9 3.4e-113 378.9 24.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC95479.1 - 2.6e-14 52.9 42.3 7.6e-13 48.1 29.0 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HSP70 PF00012.20 EMC95480.1 - 5.3e-226 751.5 10.4 5.9e-226 751.3 10.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMC95480.1 - 2e-16 59.8 0.2 3.1e-15 55.8 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EMC95480.1 - 3.6e-05 23.6 0.0 8.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EMC95480.1 - 0.011 14.7 0.2 0.3 10.0 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF2564 PF10819.8 EMC95480.1 - 0.091 13.2 0.3 4.8 7.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) p450 PF00067.22 EMC95481.1 - 2.2e-58 198.1 0.0 4.3e-58 197.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF4296 PF14129.6 EMC95481.1 - 0.048 14.3 0.3 0.092 13.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) CBFD_NFYB_HMF PF00808.23 EMC95482.1 - 2.3e-29 101.5 1.0 3.2e-29 101.0 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMC95482.1 - 5.4e-06 26.8 0.0 8.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EMC95482.1 - 0.00075 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EMC95482.1 - 0.0013 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EMC95482.1 - 0.0045 17.1 0.0 0.0061 16.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EMC95482.1 - 0.047 14.2 0.0 0.087 13.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 EMC95485.1 - 2.1e-24 85.5 5.0 2.5e-24 85.3 5.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit p25-alpha PF05517.12 EMC95485.1 - 0.071 13.3 0.9 0.94 9.6 0.0 2.0 2 0 0 2 2 2 0 p25-alpha DUF2089 PF09862.9 EMC95485.1 - 0.078 13.0 0.5 0.97 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) EAP30 PF04157.16 EMC95485.1 - 0.25 10.6 2.9 2.2 7.5 0.4 2.4 1 1 0 2 2 2 0 EAP30/Vps36 family DUF2205 PF10224.9 EMC95485.1 - 0.52 10.4 8.8 0.17 11.9 1.8 2.3 2 1 0 2 2 2 0 Short coiled-coil protein SLATT_1 PF18181.1 EMC95485.1 - 0.65 9.9 4.3 0.38 10.7 0.7 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Spc24 PF08286.11 EMC95485.1 - 1.7 8.9 7.2 3.4 8.0 1.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cmc1 PF08583.10 EMC95486.1 - 1.7e-20 72.8 5.2 1.9e-20 72.6 5.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 EMC95486.1 - 1.3 9.4 4.8 3.9 7.9 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) DUF1586 PF07625.11 EMC95487.1 - 0.11 12.6 1.3 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) MnmE_helical PF12631.7 EMC95488.1 - 0.0056 16.9 0.1 0.054 13.7 0.0 2.1 2 0 0 2 2 2 1 MnmE helical domain TOM20_plant PF06552.12 EMC95488.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_1 PF00515.28 EMC95488.1 - 4 7.4 5.5 2.5 8.1 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 EMC95490.1 - 6.7e-41 140.6 13.2 5.6e-40 137.6 6.0 3.3 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like Pex26 PF07163.12 EMC95490.1 - 6.9e-06 25.6 0.4 1.5e-05 24.5 0.4 1.5 1 0 0 1 1 1 1 Pex26 protein TPR_2 PF07719.17 EMC95490.1 - 0.0081 16.2 2.1 0.29 11.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4286 PF14114.6 EMC95490.1 - 0.043 14.3 0.0 0.16 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) TPR_1 PF00515.28 EMC95490.1 - 0.07 13.0 0.6 0.55 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AlaDh_PNT_C PF01262.21 EMC95492.1 - 0.03 13.6 0.1 0.03 13.6 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain zf-GRF PF06839.12 EMC95493.1 - 0.011 15.8 4.9 0.011 15.8 4.9 2.6 2 1 0 2 2 2 0 GRF zinc finger Rhodanese_C PF12368.8 EMC95493.1 - 0.084 13.3 5.8 0.21 12.0 5.3 1.9 2 1 0 2 2 2 0 Rhodanase C-terminal Zn_ribbon_recom PF13408.6 EMC95493.1 - 7.9 7.1 12.5 5.9 7.5 9.3 2.0 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain PepX_C PF08530.10 EMC95494.1 - 8.8e-43 146.8 0.0 1.3e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EMC95494.1 - 5.5e-39 134.4 0.8 7.9e-39 133.9 0.8 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EMC95494.1 - 0.0049 16.2 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 NAGLU_C PF12972.7 EMC95496.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Fungal_trans PF04082.18 EMC95497.1 - 7.7e-11 41.5 0.2 1.2e-10 40.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EMC95498.1 - 2.5e-13 49.8 5.9 7.1e-11 42.0 2.2 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EMC95498.1 - 3.8e-09 36.5 7.5 7e-07 29.4 2.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC95498.1 - 4.9e-06 26.9 7.1 8e-05 23.2 1.9 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMC95498.1 - 2.9e-05 24.0 7.0 0.002 18.1 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMC95498.1 - 0.0003 21.0 1.4 0.34 11.3 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EMC95498.1 - 0.0014 18.5 2.3 0.018 14.9 0.1 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.7 EMC95498.1 - 0.0038 17.6 2.9 0.035 14.5 0.4 2.4 2 1 0 2 2 2 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 EMC95498.1 - 0.0066 16.5 3.5 0.014 15.5 3.5 1.5 1 1 0 1 1 1 1 Zinc ribbon domain NADH-G_4Fe-4S_3 PF10588.9 EMC95498.1 - 0.0086 15.6 0.8 0.3 10.7 0.1 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region TRAF6_Z2 PF18048.1 EMC95498.1 - 0.0087 16.1 4.0 1.1 9.4 0.5 2.5 2 1 0 2 2 2 2 TNF receptor-associated factor 6 zinc finger 2 C1_4 PF07975.12 EMC95498.1 - 0.0094 16.2 3.4 0.054 13.7 3.4 1.8 1 1 1 2 2 2 2 TFIIH C1-like domain zinc-ribbons_6 PF07191.12 EMC95498.1 - 0.012 15.5 2.6 0.3 11.1 2.6 2.0 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_4 PF13717.6 EMC95498.1 - 0.017 15.0 3.2 0.89 9.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain gag_pre-integrs PF13976.6 EMC95498.1 - 0.02 14.7 1.2 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 GAG-pre-integrase domain Zn_Tnp_IS1595 PF12760.7 EMC95498.1 - 0.023 14.6 3.3 1.5 8.9 0.4 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_9 PF14369.6 EMC95498.1 - 0.026 14.8 1.3 0.27 11.5 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon DUF2256 PF10013.9 EMC95498.1 - 0.033 14.3 1.9 2.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 EMC95498.1 - 0.039 13.6 0.8 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EMC95498.1 - 0.077 13.3 4.0 0.13 12.6 4.0 1.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 EMC95498.1 - 0.12 12.4 0.9 0.15 12.1 0.9 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HE PF16278.5 EMC95498.1 - 0.15 12.5 3.1 1.2 9.6 0.3 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 EMC95498.1 - 0.16 11.7 2.8 0.22 11.2 2.6 1.4 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-AN1 PF01428.16 EMC95498.1 - 0.2 11.9 7.3 3.3 7.9 1.6 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger Zn-C2H2_12 PF18112.1 EMC95498.1 - 0.23 11.9 3.2 2 8.9 0.1 2.4 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Elf1 PF05129.13 EMC95498.1 - 0.29 11.2 4.9 2.4 8.3 0.6 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like LigB PF02900.18 EMC95499.1 - 1.5e-09 37.4 0.0 1.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase p450 PF00067.22 EMC95500.1 - 1.3e-69 235.2 0.0 1.6e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 EMC95501.1 - 2.1e-08 33.8 0.1 5.5e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EMC95501.1 - 1.4e-05 24.8 0.0 0.00012 21.7 0.0 2.1 1 1 0 2 2 2 1 Cupin FAD_binding_3 PF01494.19 EMC95502.1 - 7.3e-19 68.2 0.7 1.2e-17 64.2 0.7 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC95502.1 - 3.5e-07 29.8 0.3 0.01 15.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC95502.1 - 0.00022 21.7 0.0 0.32 11.6 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC95502.1 - 0.00087 18.3 0.1 0.43 9.4 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EMC95502.1 - 0.026 14.8 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC95502.1 - 0.054 13.1 1.4 0.14 11.7 0.5 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMC95502.1 - 0.16 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAA_hydrolase PF01557.18 EMC95503.1 - 1e-47 162.6 0.0 1.4e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EMC95503.1 - 3.7e-24 85.0 0.1 6.8e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Sirohm_synth_M PF14824.6 EMC95503.1 - 0.03 13.8 0.5 9.3 5.8 0.0 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central adh_short_C2 PF13561.6 EMC95504.1 - 7e-40 137.0 0.2 8.6e-40 136.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC95504.1 - 6.9e-30 104.0 0.2 9e-30 103.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC95504.1 - 1.3e-07 31.7 1.1 1.9e-07 31.2 1.1 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EMC95505.1 - 1.3e-19 70.4 0.2 2.4e-19 69.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC95505.1 - 5.1e-17 61.7 0.1 1e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMC95505.1 - 0.0033 18.5 0.1 0.0072 17.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ins_beta PF03488.14 EMC95505.1 - 0.049 13.6 1.1 0.091 12.8 1.1 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type MFS_1 PF07690.16 EMC95506.1 - 3.7e-29 101.7 21.8 3.7e-29 101.7 21.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC95506.1 - 4.6e-15 55.4 1.2 4.6e-15 55.4 1.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EMC95506.1 - 1.4e-06 27.1 2.2 2.5e-06 26.2 2.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FixP_N PF14715.6 EMC95506.1 - 0.02 14.6 0.0 0.11 12.2 0.0 2.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP p450 PF00067.22 EMC95507.1 - 1.2e-56 192.4 0.0 1.5e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M1_N PF17900.1 EMC95508.1 - 1.9e-05 24.9 0.0 0.32 11.1 0.0 2.6 3 0 0 3 3 3 2 Peptidase M1 N-terminal domain Aminotran_1_2 PF00155.21 EMC95510.1 - 1.4e-17 64.0 0.0 1.8e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EMC95510.1 - 1.9e-05 23.7 0.0 5.2e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Lsm_interact PF05391.11 EMC95510.1 - 0.27 10.8 0.8 0.7 9.5 0.8 1.7 1 0 0 1 1 1 0 Lsm interaction motif MGC-24 PF05283.11 EMC95512.1 - 0.45 11.0 7.3 0.088 13.3 3.5 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RskA PF10099.9 EMC95512.1 - 2.3 8.5 12.6 0.16 12.3 5.8 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Mucin PF01456.17 EMC95512.1 - 7.6 6.5 20.9 0.95 9.5 13.0 2.7 3 0 0 3 3 3 0 Mucin-like glycoprotein SAS4 PF15460.6 EMC95513.1 - 7.9e-34 115.7 4.1 1.6e-33 114.7 4.1 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Adaptin_binding PF10199.9 EMC95513.1 - 1.2 9.7 5.6 0.44 11.2 1.6 2.3 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Transferase PF02458.15 EMC95515.1 - 4.3e-20 71.8 0.0 1.9e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 Transferase family DUF2844 PF11005.8 EMC95515.1 - 0.045 13.8 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) PCI PF01399.27 EMC95517.1 - 2.3e-22 79.5 0.2 6.1e-22 78.1 0.1 1.9 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 EMC95517.1 - 4.4e-21 75.1 0.4 1e-20 73.9 0.4 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 EMC95517.1 - 0.16 12.1 0.7 1.4 9.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DASH_Spc34 PF08657.10 EMC95518.1 - 4.6e-38 131.5 0.4 1e-18 68.0 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 Spectrin PF00435.21 EMC95518.1 - 0.0018 18.8 1.9 0.86 10.1 0.0 2.4 2 0 0 2 2 2 2 Spectrin repeat CENP-F_leu_zip PF10473.9 EMC95518.1 - 0.04 13.9 1.9 0.04 13.9 1.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MPS2 PF17060.5 EMC95518.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Peptidase_C31 PF05410.13 EMC95518.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha DUF4140 PF13600.6 EMC95518.1 - 0.27 11.7 6.2 2.5 8.6 0.4 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 EMC95518.1 - 0.54 10.1 2.7 7.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator BBS2_C PF14782.6 EMC95518.1 - 0.8 8.4 4.1 4 6.1 0.1 2.0 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Cu-oxidase PF00394.22 EMC95519.1 - 1.1e-26 93.9 0.1 2.1e-26 93.0 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMC95519.1 - 6.6e-09 35.6 1.9 5e-08 32.8 0.2 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMC95519.1 - 6.4e-07 29.4 0.5 0.0004 20.4 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase PfkB PF00294.24 EMC95520.1 - 5.5e-11 42.3 0.0 6.8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase F-box-like PF12937.7 EMC95521.1 - 0.0013 18.6 0.3 0.0032 17.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EMC95521.1 - 0.0029 17.5 1.8 0.26 11.4 0.0 3.7 4 0 0 4 4 4 1 Leucine Rich repeat GMC_oxred_N PF00732.19 EMC95522.1 - 1.1e-68 231.8 0.0 2e-68 230.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC95522.1 - 6.1e-36 124.1 0.1 9.9e-36 123.4 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 EMC95522.1 - 2.7e-05 23.5 0.2 6.3e-05 22.3 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EMC95522.1 - 3.1e-05 23.2 2.2 0.0059 15.7 0.1 3.1 2 1 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 EMC95522.1 - 9.4e-05 21.6 0.1 9.4e-05 21.6 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EMC95522.1 - 0.00025 20.8 1.4 0.001 18.7 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC95522.1 - 0.00034 20.8 0.3 0.0011 19.2 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMC95522.1 - 0.00097 18.5 0.6 0.61 9.3 0.4 2.7 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC95522.1 - 0.0056 16.0 0.2 0.061 12.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC95522.1 - 0.024 13.3 0.5 0.16 10.6 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Sugar_tr PF00083.24 EMC95523.1 - 8.2e-90 301.8 22.6 1e-89 301.5 22.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC95523.1 - 1.2e-14 54.0 37.1 2.2e-13 49.9 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_76 PF03663.14 EMC95524.1 - 9.5e-24 84.6 5.5 4.7e-17 62.6 0.1 2.7 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMC95524.1 - 0.048 12.7 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Ctr PF04145.15 EMC95525.1 - 6.9e-30 104.6 1.0 8.6e-30 104.3 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 EMC95526.1 - 1.9e-20 73.2 17.7 1.9e-20 73.2 17.7 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMC95526.1 - 1.7e-15 57.5 0.0 5.8e-15 55.7 0.0 1.9 3 0 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMC95526.1 - 8.4e-11 41.9 0.0 2.1e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain DUF4405 PF14358.6 EMC95526.1 - 0.0066 17.0 17.9 0.044 14.3 1.3 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4405) Ribosomal_L27e PF01777.18 EMC95527.1 - 9.3e-36 122.1 1.6 1.5e-35 121.4 1.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EMC95527.1 - 0.039 13.9 0.5 0.12 12.3 0.5 1.9 1 0 0 1 1 1 0 KOW motif HALZ PF02183.18 EMC95528.1 - 0.044 14.0 4.3 0.2 11.9 1.3 4.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF603 PF04645.12 EMC95528.1 - 0.048 13.4 0.2 0.74 9.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function, DUF603 DUF2730 PF10805.8 EMC95528.1 - 3.6 7.7 20.6 0.99 9.5 0.1 6.6 4 2 1 5 5 5 0 Protein of unknown function (DUF2730) Tup_N PF08581.10 EMC95528.1 - 8.5 6.8 47.9 0.73 10.2 0.0 11.7 10 2 1 12 12 12 0 Tup N-terminal AMP-binding PF00501.28 EMC95529.1 - 1.2e-66 225.1 0.0 1.7e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GMC_oxred_N PF00732.19 EMC95529.1 - 4.9e-58 196.8 0.0 9e-58 196.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC95529.1 - 5.7e-29 101.5 0.0 1.2e-28 100.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase AMP-binding_C PF13193.6 EMC95529.1 - 1.4e-16 61.3 0.0 3.7e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EMC95529.1 - 2.6e-15 56.1 1.2 2.6e-15 56.1 1.2 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus FAD_binding_2 PF00890.24 EMC95529.1 - 8.6e-12 44.8 1.0 2.7e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EMC95529.1 - 1.1e-05 24.7 0.1 2.1e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EMC95529.1 - 2e-05 24.4 0.3 0.0001 22.0 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC95529.1 - 0.00015 22.0 0.9 0.00041 20.5 0.1 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMC95529.1 - 0.00029 20.1 0.1 0.00055 19.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EMC95529.1 - 0.0024 17.2 0.0 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC95529.1 - 0.0043 16.3 0.1 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EMC95529.1 - 0.01 15.1 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC95529.1 - 0.13 10.9 0.1 0.33 9.6 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 EMC95529.1 - 0.14 12.5 0.3 1.6 9.0 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain COMMD1_N PF17221.3 EMC95530.1 - 0.05 13.9 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 COMMD1 N-terminal domain DUF433 PF04255.14 EMC95532.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Polyketide_cyc2 PF10604.9 EMC95534.1 - 0.0085 16.4 0.7 0.12 12.6 0.7 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ubiquitin PF00240.23 EMC95535.1 - 4.6e-34 116.0 0.6 7.9e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EMC95535.1 - 3.6e-26 91.0 3.1 3.6e-26 91.0 3.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EMC95535.1 - 2.6e-16 59.2 0.7 4.9e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMC95535.1 - 2.8e-05 24.5 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMC95535.1 - 0.0012 19.0 0.6 0.0026 17.8 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EMC95535.1 - 0.004 17.5 0.6 0.0079 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EMC95535.1 - 0.0055 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EMC95535.1 - 0.013 16.1 0.7 0.019 15.6 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EMC95535.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Fer2_3 PF13085.6 EMC95535.1 - 0.17 11.9 0.8 0.37 10.8 0.8 1.7 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DNA_pol_E_B PF04042.16 EMC95536.1 - 5.9e-47 159.8 0.0 9.8e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B F-box-like_2 PF13013.6 EMC95537.1 - 0.0027 17.6 0.4 0.02 14.8 0.1 2.4 2 2 0 2 2 2 1 F-box-like domain DUF3918 PF13056.6 EMC95538.1 - 0.8 9.4 2.1 1.6 8.4 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) GFO_IDH_MocA PF01408.22 EMC95539.1 - 9.1e-23 81.4 0.0 3.7e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EMC95539.1 - 0.17 12.5 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TPR_1 PF00515.28 EMC95540.1 - 1e-09 37.8 1.1 0.00046 19.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC95540.1 - 2e-09 36.9 2.4 0.073 13.2 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMC95540.1 - 0.00017 22.0 0.6 0.00017 22.0 0.6 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC95540.1 - 0.00037 20.7 3.5 0.00083 19.5 2.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EMC95540.1 - 0.0027 17.7 3.8 0.92 9.6 0.0 3.7 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat Pox_T4_N PF04491.12 EMC95540.1 - 0.003 17.4 0.2 0.0099 15.7 0.0 1.9 2 0 0 2 2 2 1 Poxvirus T4 protein, N terminus TPR_16 PF13432.6 EMC95540.1 - 0.0065 17.1 0.2 0.0065 17.1 0.2 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMC95540.1 - 0.017 15.9 5.4 0.078 13.8 0.3 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 EMC95540.1 - 0.032 13.0 0.1 0.046 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_12 PF13424.6 EMC95540.1 - 0.068 13.5 4.0 0.36 11.1 0.3 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMC95540.1 - 0.15 11.8 2.1 5.5 6.8 0.2 3.2 4 0 0 4 4 4 0 TPR repeat Mcp5_PH PF12814.7 EMC95542.1 - 3.6e-40 136.9 0.0 6.9e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 EMC95542.1 - 0.00024 21.6 14.3 0.00055 20.4 14.3 1.5 1 0 0 1 1 1 1 Fez1 Macoilin PF09726.9 EMC95542.1 - 0.00075 18.2 7.9 0.00075 18.2 7.9 2.8 3 0 0 3 3 3 1 Macoilin family TPR_MLP1_2 PF07926.12 EMC95542.1 - 0.0048 17.0 22.0 0.014 15.5 19.4 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Ribosomal_S20p PF01649.18 EMC95542.1 - 0.2 12.3 1.2 0.52 11.0 1.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S20 DUF3584 PF12128.8 EMC95542.1 - 0.28 8.6 16.8 0.38 8.2 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 EMC95542.1 - 0.71 9.3 18.1 1.4 8.3 18.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 EMC95542.1 - 0.96 8.9 9.5 1.7 8.1 9.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EMC95542.1 - 1.8 7.8 8.2 3.1 7.0 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_4 PF13637.6 EMC95544.1 - 6.9e-22 77.5 0.4 2.3e-07 31.2 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMC95544.1 - 2.1e-21 76.3 1.5 1.9e-11 44.4 0.3 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMC95544.1 - 3.3e-19 66.9 0.7 0.00082 19.6 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EMC95544.1 - 1.4e-18 66.4 5.6 0.0022 18.4 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EMC95544.1 - 1.2e-14 54.2 6.0 0.00018 21.7 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) HicA_toxin PF07927.12 EMC95544.1 - 0.039 14.0 0.0 34 4.6 0.0 3.6 4 0 0 4 4 4 0 HicA toxin of bacterial toxin-antitoxin, RPN6_N PF18055.1 EMC95544.1 - 0.069 13.5 0.0 1 9.8 0.0 2.3 2 1 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Archease PF01951.16 EMC95544.1 - 0.21 11.9 0.3 34 4.7 0.0 2.7 2 1 1 3 3 3 0 Archease protein family (MTH1598/TM1083) NACHT PF05729.12 EMC95545.1 - 9.5e-09 35.4 0.0 2.5e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EMC95545.1 - 3.4e-06 27.6 0.0 1.1e-05 25.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EMC95545.1 - 6e-05 23.3 0.0 0.0002 21.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EMC95545.1 - 0.0039 16.5 0.6 0.79 8.9 0.1 2.3 1 1 0 2 2 2 2 KAP family P-loop domain DIMCO_N PF16844.5 EMC95545.1 - 0.019 15.2 0.1 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Viral_helicase1 PF01443.18 EMC95545.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EMC95545.1 - 0.024 15.1 0.1 0.23 11.9 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EMC95545.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMC95545.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EMC95545.1 - 0.069 13.5 0.0 0.39 11.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 EMC95545.1 - 0.093 12.6 0.0 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EMC95545.1 - 0.1 11.8 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Ploopntkinase3 PF18751.1 EMC95545.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 EMC95545.1 - 0.15 12.1 0.0 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMC95545.1 - 0.16 12.5 0.0 0.45 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMC95545.1 - 0.17 12.1 0.1 0.56 10.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain HET PF06985.11 EMC95546.1 - 7.8e-15 55.5 2.5 8.1e-11 42.5 0.2 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3256 PF11644.8 EMC95546.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3256) Oxidored_molyb PF00174.19 EMC95547.1 - 4.4e-54 182.7 0.0 7.5e-54 181.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EMC95547.1 - 6.7e-37 126.6 1.1 1.5e-36 125.4 1.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 EMC95547.1 - 5e-20 72.2 0.1 3.1e-19 69.6 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMC95547.1 - 6.1e-20 71.4 0.0 1.2e-08 35.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EMC95547.1 - 2.6e-13 49.9 0.1 7.6e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zn_clus PF00172.18 EMC95549.1 - 1.1e-08 35.0 8.6 2e-08 34.2 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC95549.1 - 1.1e-06 27.9 0.0 3.8e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Redoxin PF08534.10 EMC95550.1 - 2.9e-29 101.7 0.0 3.4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMC95550.1 - 2e-08 34.2 0.0 2.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.17 EMC95551.1 - 5.3e-31 107.1 0.3 9.8e-31 106.2 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EMC95551.1 - 1e-21 77.2 0.1 2.2e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain W2 PF02020.18 EMC95552.1 - 1.6e-09 37.7 3.4 5.4e-09 36.1 3.4 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EMC95552.1 - 1.3e-07 31.0 10.3 0.0026 17.4 0.7 3.8 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EMC95552.1 - 0.00088 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EMC95552.1 - 0.0077 16.6 0.0 0.028 14.8 0.0 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EMC95552.1 - 0.01 15.5 6.4 0.91 9.3 1.0 3.5 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase SEEK1 PF15357.6 EMC95553.1 - 0.053 13.7 0.4 0.056 13.6 0.4 1.1 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 Methyltransf_25 PF13649.6 EMC95554.1 - 1.4e-09 38.5 0.0 2.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC95554.1 - 1.4e-09 38.5 0.0 3.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC95554.1 - 1.2e-05 25.9 0.0 1.9e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC95554.1 - 0.00024 20.9 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EMC95554.1 - 0.03 13.5 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Pil1 PF13805.6 EMC95555.1 - 1.2e-93 313.5 6.2 1.4e-93 313.2 6.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Spc24 PF08286.11 EMC95555.1 - 4.5 7.6 8.1 2.4 8.4 4.0 2.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 PKcGMP_CC PF16808.5 EMC95556.1 - 0.0097 15.7 11.5 2 8.3 0.9 4.5 4 0 0 4 4 4 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4200 PF13863.6 EMC95556.1 - 0.014 15.8 10.3 0.17 12.3 0.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) YlzJ PF14035.6 EMC95556.1 - 0.015 15.5 0.1 0.14 12.3 0.0 2.5 2 0 0 2 2 2 0 YlzJ-like protein BAR_3 PF16746.5 EMC95556.1 - 0.017 14.8 0.9 0.017 14.8 0.9 1.9 2 0 0 2 2 2 0 BAR domain of APPL family ZapB PF06005.12 EMC95556.1 - 0.026 15.0 20.9 13 6.3 5.9 5.8 3 1 1 4 4 3 0 Cell division protein ZapB DUF641 PF04859.12 EMC95556.1 - 0.037 14.4 7.3 0.33 11.3 0.5 3.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Spc42p PF11544.8 EMC95556.1 - 0.04 13.9 3.0 0.23 11.5 0.1 3.0 2 1 1 3 3 3 0 Spindle pole body component Spc42p UPF0242 PF06785.11 EMC95556.1 - 0.058 13.5 20.1 0.031 14.4 7.8 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Vps54_N PF10475.9 EMC95556.1 - 0.11 11.7 5.2 0.025 13.9 1.0 2.0 2 1 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex bZIP_1 PF00170.21 EMC95556.1 - 0.17 12.0 1.8 1.8 8.7 0.1 3.2 3 0 0 3 3 3 0 bZIP transcription factor TSC22 PF01166.18 EMC95556.1 - 0.71 10.2 4.7 0.94 9.8 0.5 3.2 3 1 1 4 4 4 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 EMC95556.1 - 0.77 9.8 22.7 0.58 10.2 4.4 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 EMC95556.1 - 0.79 10.2 9.6 1.7 9.1 0.6 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.8 EMC95556.1 - 0.88 9.6 15.2 0.22 11.6 1.0 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 EMC95556.1 - 0.95 9.8 12.7 0.12 12.6 6.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 EMC95556.1 - 1.3 7.8 17.5 1.4 7.7 3.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 EMC95556.1 - 1.5 9.2 7.2 4.8 7.5 0.8 3.6 2 1 1 3 3 3 0 Uncharacterized conserved protein Filament PF00038.21 EMC95556.1 - 1.6 8.3 17.7 0.65 9.5 11.7 2.5 1 1 1 2 2 2 0 Intermediate filament protein Gp58 PF07902.11 EMC95556.1 - 2.3 6.4 8.1 3.3 5.9 8.1 1.2 1 0 0 1 1 1 0 gp58-like protein Occludin_ELL PF07303.13 EMC95556.1 - 2.5 8.9 5.2 4.7 8.0 0.3 3.0 2 1 0 2 2 2 0 Occludin homology domain DUF4201 PF13870.6 EMC95556.1 - 2.5 7.8 10.6 4.1 7.1 1.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF2203 PF09969.9 EMC95556.1 - 3 8.6 11.3 14 6.4 1.6 3.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.19 EMC95556.1 - 5.7 4.7 7.8 4.2 5.2 6.3 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family adh_short PF00106.25 EMC95558.1 - 2.9e-37 128.0 0.1 1.4e-36 125.8 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC95558.1 - 6.7e-35 120.7 0.0 2.2e-22 79.8 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 EMC95558.1 - 1.8e-05 24.8 0.1 4.5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.10 EMC95558.1 - 9.9e-05 22.3 0.4 9.9e-05 22.3 0.4 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMC95558.1 - 0.014 14.9 0.1 0.095 12.1 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC95558.1 - 0.035 14.0 0.4 0.09 12.7 0.2 1.7 2 1 0 2 2 2 0 NAD(P)H-binding AlaDh_PNT_C PF01262.21 EMC95558.1 - 0.12 11.6 0.9 0.2 10.9 0.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NFACT-C PF11923.8 EMC95559.1 - 2.7e-43 146.2 0.3 2.7e-43 146.2 0.3 3.6 4 0 0 4 4 4 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 EMC95559.1 - 4e-31 107.9 0.0 9.5e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 EMC95559.1 - 3.9e-28 98.4 15.8 3.9e-28 98.4 15.8 2.9 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) CRR7 PF12095.8 EMC95559.1 - 3.7 8.1 6.2 6.6 7.2 0.1 3.4 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Redoxin PF08534.10 EMC95560.1 - 4.6e-33 114.0 0.1 5.2e-33 113.8 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMC95560.1 - 4.5e-13 49.2 0.0 6.9e-13 48.6 0.0 1.3 2 0 0 2 2 2 1 AhpC/TSA family Spem1 PF15670.5 EMC95561.1 - 0.095 12.3 0.7 0.13 11.8 0.7 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 AAA PF00004.29 EMC95562.1 - 7.1e-52 175.3 0.0 1.7e-39 135.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMC95562.1 - 5.5e-12 46.4 0.1 0.00039 20.9 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 EMC95562.1 - 7.5e-12 44.9 0.1 1.9e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 EMC95562.1 - 4e-10 39.3 0.1 6.2e-09 35.5 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EMC95562.1 - 9.1e-10 38.9 0.0 0.0016 18.7 0.0 3.9 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 EMC95562.1 - 5.7e-08 32.4 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 EMC95562.1 - 1.1e-07 31.7 0.2 0.03 14.1 0.0 3.3 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EMC95562.1 - 1.9e-07 31.2 0.1 0.002 18.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EMC95562.1 - 2.2e-07 31.5 0.0 0.014 15.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.14 EMC95562.1 - 3.5e-07 30.5 0.0 9.4e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EMC95562.1 - 5.6e-07 29.8 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EMC95562.1 - 7e-07 28.8 0.1 0.0054 16.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EMC95562.1 - 9e-07 28.8 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EMC95562.1 - 3.5e-06 27.0 0.4 0.032 14.2 0.0 3.5 4 0 0 4 4 3 1 NACHT domain Sigma54_activat PF00158.26 EMC95562.1 - 4e-06 26.6 0.1 0.26 11.0 0.0 3.5 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_14 PF13173.6 EMC95562.1 - 5.6e-06 26.4 0.0 0.038 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EMC95562.1 - 6.3e-06 26.5 0.0 0.042 14.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase CDC48_N PF02359.18 EMC95562.1 - 1.1e-05 25.6 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.17 EMC95562.1 - 1.4e-05 24.9 0.0 0.044 13.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 EMC95562.1 - 1.8e-05 24.7 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EMC95562.1 - 4e-05 23.2 0.1 0.032 13.7 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 EMC95562.1 - 8.3e-05 23.1 0.2 0.033 14.7 0.1 2.5 2 0 0 2 2 2 1 ABC transporter ATPase_2 PF01637.18 EMC95562.1 - 0.00019 21.4 0.3 3 7.7 0.0 3.3 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EMC95562.1 - 0.00023 20.4 0.0 0.48 9.6 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_28 PF13521.6 EMC95562.1 - 0.00045 20.5 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EMC95562.1 - 0.0019 18.0 0.0 0.63 9.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EMC95562.1 - 0.0021 17.5 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.6 EMC95562.1 - 0.0028 17.2 0.0 2.5 7.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.6 EMC95562.1 - 0.0043 17.5 0.1 5 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EMC95562.1 - 0.0046 16.3 0.1 0.15 11.3 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.6 EMC95562.1 - 0.0069 16.1 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EMC95562.1 - 0.0095 15.8 0.0 0.45 10.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EMC95562.1 - 0.019 15.3 0.1 0.62 10.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 EMC95562.1 - 0.024 14.7 0.2 9 6.3 0.2 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 EMC95562.1 - 0.03 13.7 0.1 3.8 6.9 0.0 3.1 2 1 1 3 3 3 0 Bacterial TniB protein Parvo_NS1 PF01057.17 EMC95562.1 - 0.034 13.2 0.0 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 EMC95562.1 - 0.035 13.3 0.1 1.2 8.3 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 EMC95562.1 - 0.045 12.9 0.1 9.2 5.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Vps4_C PF09336.10 EMC95562.1 - 0.059 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_29 PF13555.6 EMC95562.1 - 0.065 13.0 0.0 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AFG1_ATPase PF03969.16 EMC95562.1 - 0.07 12.0 0.0 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase EAP30 PF04157.16 EMC95562.1 - 0.093 12.0 0.2 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 EAP30/Vps36 family Zeta_toxin PF06414.12 EMC95562.1 - 0.1 11.9 0.0 6.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 EMC95562.1 - 0.11 12.6 0.0 28 4.8 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 EMC95562.1 - 0.15 11.8 0.0 23 4.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 EMC95562.1 - 0.18 11.7 0.0 3.6 7.5 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain KxDL PF10241.9 EMC95563.1 - 1.6e-30 105.2 2.4 2.1e-30 104.8 2.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.11 EMC95563.1 - 0.057 13.2 0.9 0.091 12.5 0.9 1.3 1 0 0 1 1 1 0 Activator of aromatic catabolism Atg14 PF10186.9 EMC95563.1 - 0.13 11.3 1.1 0.18 10.8 1.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_S PF02609.16 EMC95563.1 - 0.19 11.8 0.5 1.9 8.6 0.1 2.6 2 1 1 3 3 3 0 Exonuclease VII small subunit DUF4407 PF14362.6 EMC95563.1 - 0.4 10.0 5.5 0.5 9.7 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EMC95563.1 - 1.2 9.5 6.7 1.9 8.8 6.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SURF6 PF04935.12 EMC95566.1 - 1.8e-48 165.0 39.9 1.8e-48 165.0 39.9 4.1 3 1 1 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.6 EMC95566.1 - 1.4e-14 54.4 2.1 1.4e-14 54.4 2.1 6.5 4 2 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 Patatin PF01734.22 EMC95568.1 - 9e-15 55.4 0.0 1.7e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase PP-binding PF00550.25 EMC95569.1 - 9e-12 45.2 0.3 1.2e-11 44.7 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EMC95569.1 - 1.6e-05 25.0 0.1 2.3e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.11 EMC95570.1 - 6.1e-70 235.4 0.9 7.6e-70 235.1 0.4 1.4 2 0 0 2 2 2 1 Golgi phosphoprotein 3 (GPP34) SNF5 PF04855.12 EMC95571.1 - 3.5e-61 207.0 4.5 7e-60 202.8 4.5 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PHD PF00628.29 EMC95572.1 - 7e-15 54.6 16.6 3.4e-09 36.4 6.1 2.5 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 EMC95572.1 - 0.0047 17.2 5.5 0.022 15.0 1.2 2.6 2 0 0 2 2 2 1 PHD-like zinc-binding domain C1_1 PF00130.22 EMC95572.1 - 0.052 13.4 9.2 0.8 9.6 0.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EMC95572.1 - 0.083 12.5 7.1 0.47 10.1 0.9 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF2321 PF10083.9 EMC95572.1 - 0.71 9.5 2.1 2.3 7.8 2.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Syntaxin-18_N PF10496.9 EMC95572.1 - 1.6 9.0 5.7 0.39 11.0 0.9 2.6 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus zf-HC5HC2H_2 PF13832.6 EMC95572.1 - 3.1 8.0 4.8 3.5 7.8 1.7 2.3 2 0 0 2 2 2 0 PHD-zinc-finger like domain Peptidase_M24 PF00557.24 EMC95573.1 - 2.5e-09 37.2 0.1 5e-09 36.2 0.1 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 RNA_pol_3_Rpc31 PF11705.8 EMC95573.1 - 0.00057 20.2 5.7 0.00057 20.2 5.7 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 EMC95573.1 - 0.35 10.6 14.7 0.54 9.9 14.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Red1 PF07964.11 EMC95573.1 - 0.65 8.2 9.4 1.1 7.4 9.4 1.3 1 0 0 1 1 1 0 Rec10 / Red1 ANAPC15 PF15243.6 EMC95573.1 - 0.89 10.0 12.9 1.7 9.1 12.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Pox_Ag35 PF03286.14 EMC95573.1 - 1.2 8.9 14.8 2.2 8.0 14.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 EMC95573.1 - 2 8.4 10.7 4.2 7.4 8.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal WRNPLPNID PF15017.6 EMC95573.1 - 2.8 8.9 9.3 6.3 7.7 9.3 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box FAM176 PF14851.6 EMC95573.1 - 4.9 6.8 8.8 8 6.1 8.8 1.3 1 0 0 1 1 1 0 FAM176 family Glyco_transf_20 PF00982.21 EMC95574.1 - 3.1e-147 491.1 0.0 4.3e-147 490.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EMC95574.1 - 1.1e-83 280.0 0.0 2.2e-83 278.9 0.0 1.5 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EMC95574.1 - 0.00022 21.0 0.0 0.06 13.1 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Fer4 PF00037.27 EMC95575.1 - 3.6e-14 51.9 13.8 3.9e-08 32.8 2.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EMC95575.1 - 1.8e-13 50.8 9.3 2.9e-13 50.2 9.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EMC95575.1 - 6.4e-11 43.0 6.2 2.4e-05 25.2 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EMC95575.1 - 9.2e-09 35.3 21.9 2.1e-06 27.7 12.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EMC95575.1 - 1e-08 35.2 21.5 2.2e-06 27.7 12.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EMC95575.1 - 1.1e-08 35.1 9.8 1.9e-08 34.3 9.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EMC95575.1 - 1.6e-07 31.7 19.2 4.5e-05 23.8 11.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EMC95575.1 - 3.4e-06 26.9 16.7 0.00039 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EMC95575.1 - 4.2e-06 26.5 11.7 0.01 15.9 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EMC95575.1 - 6.3e-06 26.3 10.8 0.00029 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EMC95575.1 - 0.00027 21.4 12.2 0.019 15.5 12.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 EMC95575.1 - 0.01 16.7 15.7 0.018 16.0 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 EMC95575.1 - 0.033 14.4 4.9 0.78 10.0 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EMC95575.1 - 0.062 13.5 8.7 1.2 9.3 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EMC95575.1 - 0.073 13.6 15.2 0.74 10.4 4.3 2.7 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 EMC95575.1 - 0.15 12.2 5.0 0.36 11.0 0.5 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 EMC95575.1 - 0.48 11.3 11.3 3.1 8.7 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain PAP_assoc PF03828.19 EMC95576.1 - 8.7e-05 22.7 0.1 0.001 19.2 0.1 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EMC95576.1 - 0.00048 20.4 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D5 PF17406.2 EMC95576.1 - 0.031 14.1 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Polbeta PF18765.1 EMC95576.1 - 0.036 14.1 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Herpes_gE PF02480.16 EMC95578.1 - 0.015 14.1 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E YtxH PF12732.7 EMC95578.1 - 4.6 7.8 5.9 34 5.0 3.6 2.5 2 0 0 2 2 2 0 YtxH-like protein Mito_carr PF00153.27 EMC95581.1 - 3.1e-58 193.7 5.3 1.3e-19 69.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Virul_fac_BrkB PF03631.15 EMC95582.1 - 0.0083 15.8 6.0 0.0083 15.8 6.0 2.1 2 0 0 2 2 2 1 Virulence factor BrkB CorA PF01544.18 EMC95583.1 - 5.6e-06 25.9 0.1 1e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF485 PF04341.12 EMC95583.1 - 0.86 9.6 3.2 1.6 8.8 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 EI24 PF07264.11 EMC95584.1 - 2.4e-13 50.7 10.4 2.9e-13 50.4 10.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2417 PF10329.9 EMC95584.1 - 0.098 12.1 5.8 0.18 11.2 5.8 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF4231 PF14015.6 EMC95584.1 - 0.88 10.1 3.3 2.2 8.8 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Vac14_Fig4_bd PF11916.8 EMC95585.1 - 3.2e-77 258.2 6.4 3.2e-77 258.2 6.4 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EMC95585.1 - 2.7e-45 152.9 1.0 3.2e-42 143.1 0.1 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EMC95585.1 - 1.7e-09 37.9 6.0 0.0089 16.5 0.1 5.4 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EMC95585.1 - 6.1e-07 29.2 2.9 0.0011 19.0 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 EMC95585.1 - 5.9e-06 26.4 4.7 0.16 12.0 0.2 4.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMC95585.1 - 8.8e-06 26.0 6.3 0.19 12.2 0.1 6.1 6 0 0 6 6 6 1 HEAT repeats Arm PF00514.23 EMC95585.1 - 0.011 15.8 2.7 15 5.8 0.0 5.4 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat ParcG PF10274.9 EMC95585.1 - 0.027 14.6 2.5 5.3 7.1 0.0 3.1 4 1 0 4 4 4 0 Parkin co-regulated protein DUF3385 PF11865.8 EMC95585.1 - 0.1 12.5 0.1 35 4.2 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) UME PF08064.13 EMC95585.1 - 0.11 12.4 1.1 25 4.8 0.1 3.2 3 0 0 3 3 3 0 UME (NUC010) domain tRNA-synt_2 PF00152.20 EMC95586.1 - 6.6e-85 284.9 0.0 8.5e-85 284.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMC95586.1 - 5.4e-09 35.9 0.0 9.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Pyr_redox_2 PF07992.14 EMC95587.1 - 2.1e-68 230.8 7.8 2.6e-68 230.4 6.7 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMC95587.1 - 1.3e-39 134.8 1.3 1.6e-39 134.5 0.2 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMC95587.1 - 1.7e-21 76.6 11.2 6.1e-20 71.6 1.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC95587.1 - 1.7e-10 41.0 2.8 3e-06 27.4 0.5 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMC95587.1 - 3.9e-09 36.4 0.2 3.9e-09 36.4 0.2 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMC95587.1 - 7.6e-08 32.0 7.6 3.4e-06 26.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC95587.1 - 2.8e-07 30.0 3.3 2.8e-07 30.0 3.3 2.6 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 EMC95587.1 - 8.1e-07 28.5 3.4 8.1e-07 28.5 3.4 2.8 2 2 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EMC95587.1 - 1.4e-06 27.8 5.0 0.011 15.0 0.9 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EMC95587.1 - 1.5e-05 24.4 3.8 2.9e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EMC95587.1 - 2.3e-05 23.3 16.2 0.00013 20.8 2.2 4.1 3 1 1 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 EMC95587.1 - 3.5e-05 23.1 1.0 0.19 10.8 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EMC95587.1 - 0.00021 21.0 15.0 0.005 16.5 0.6 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMC95587.1 - 0.0045 16.1 3.6 0.011 14.8 0.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EMC95587.1 - 0.025 13.8 12.0 0.53 9.5 1.3 3.6 3 1 1 4 4 4 0 FAD binding domain NAD_binding_7 PF13241.6 EMC95587.1 - 0.088 13.3 3.9 0.96 9.9 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 EMC95587.1 - 0.98 7.8 3.0 0.75 8.1 0.8 1.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 EMC95587.1 - 1.9 7.3 6.2 0.34 9.7 0.8 2.2 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 EMC95587.1 - 3.6 7.1 5.7 2.7 7.5 0.5 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EMC95587.1 - 4.6 7.1 8.2 0.97 9.3 1.3 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain COQ9 PF08511.11 EMC95588.1 - 1.5e-28 98.4 0.0 2.4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 COQ9 AA_permease_2 PF13520.6 EMC95589.1 - 7.7e-55 186.4 52.6 9.2e-55 186.2 52.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC95589.1 - 1.5e-24 86.4 41.6 2.2e-24 85.9 41.6 1.1 1 0 0 1 1 1 1 Amino acid permease Malic_M PF03949.15 EMC95590.1 - 6.2e-94 314.1 0.0 8.2e-94 313.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EMC95590.1 - 4.7e-63 212.3 0.0 1.1e-62 211.0 0.0 1.6 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain DUF4449 PF14613.6 EMC95591.1 - 0.00013 22.1 5.2 0.00024 21.2 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) HMW1C_N PF18071.1 EMC95591.1 - 0.0057 16.5 0.4 0.23 11.3 0.0 3.0 3 0 0 3 3 3 1 HMW1C N-terminal FCD PF07729.12 EMC95591.1 - 0.03 14.8 0.1 0.34 11.3 0.1 2.8 1 1 1 2 2 2 0 FCD domain Ku_PK_bind PF08785.11 EMC95591.1 - 0.093 12.9 1.2 0.82 9.8 0.1 2.8 3 0 0 3 3 3 0 Ku C terminal domain like VPS28 PF03997.12 EMC95591.1 - 5.8 6.5 8.2 1.9 8.1 2.4 2.6 2 1 0 2 2 2 0 VPS28 protein CHASE3 PF05227.13 EMC95591.1 - 8.2 6.3 10.5 0.57 10.1 0.6 3.6 2 1 0 3 3 3 0 CHASE3 domain Sulfatase_C PF14707.6 EMC95591.1 - 9.8 6.9 6.3 40 5.0 0.1 3.7 4 0 0 4 4 4 0 C-terminal region of aryl-sulfatase muHD PF10291.9 EMC95592.1 - 2.6e-65 220.5 0.0 3.8e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EMC95592.1 - 3.4e-06 27.3 0.0 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR_3 PF16746.5 EMC95592.1 - 0.033 13.9 1.2 0.05 13.3 1.2 1.1 1 0 0 1 1 1 0 BAR domain of APPL family Vps5 PF09325.10 EMC95592.1 - 0.079 12.5 1.6 0.13 11.8 1.6 1.3 1 0 0 1 1 1 0 Vps5 C terminal like Laminin_II PF06009.12 EMC95592.1 - 0.096 12.7 0.9 0.22 11.5 0.9 1.6 1 0 0 1 1 1 0 Laminin Domain II Muted PF14942.6 EMC95592.1 - 0.48 10.7 2.4 0.97 9.8 2.4 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein T7SS_ESX_EspC PF10824.8 EMC95592.1 - 0.57 10.7 7.2 13 6.3 0.5 2.9 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Acyl-CoA_dh_2 PF08028.11 EMC95592.1 - 1.9 8.8 6.4 48 4.2 5.6 2.7 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain HSP20 PF00011.21 EMC95593.1 - 3.7e-20 72.0 1.6 1.5e-14 53.9 0.2 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EMC95593.1 - 7.6e-07 28.6 0.0 0.0011 18.4 0.0 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA FKBP26_C PF18046.1 EMC95593.1 - 0.098 12.8 0.0 2.1 8.5 0.0 2.6 3 0 0 3 3 3 0 FKBP26_C-terminal SAGA-Tad1 PF12767.7 EMC95595.1 - 3.1e-53 181.0 0.0 3.9e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit NAD_binding_8 PF13450.6 EMC95596.1 - 4.9e-08 33.1 0.0 1.5e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMC95596.1 - 9.3e-08 31.8 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EMC95596.1 - 0.0022 17.3 0.2 0.0043 16.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC95596.1 - 0.003 16.8 0.0 0.06 12.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC95596.1 - 0.0081 15.4 0.0 0.021 14.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EMC95596.1 - 0.012 14.8 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EMC95596.1 - 0.028 14.4 0.0 0.25 11.3 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 EMC95596.1 - 0.049 13.2 0.2 0.085 12.4 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EMC95596.1 - 0.074 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 EMC95596.1 - 0.18 10.8 0.1 0.39 9.7 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein TPT PF03151.16 EMC95598.1 - 1.7e-28 99.8 23.1 2.2e-28 99.5 23.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EMC95598.1 - 2.1e-06 27.2 22.3 8.4e-06 25.2 22.3 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EMC95598.1 - 0.00098 19.3 12.6 0.00098 19.3 12.6 2.5 3 0 0 3 3 3 2 EamA-like transporter family NYN PF01936.18 EMC95600.1 - 0.0011 19.4 0.0 0.0084 16.6 0.0 2.0 1 1 0 1 1 1 1 NYN domain Mito_carr PF00153.27 EMC95601.1 - 4e-46 154.9 1.2 6.2e-16 58.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rab5ip PF07019.12 EMC95601.1 - 0.074 13.7 0.1 0.074 13.7 0.1 3.1 3 1 1 4 4 4 0 Rab5-interacting protein (Rab5ip) RRM_1 PF00076.22 EMC95602.1 - 8.1e-50 166.5 0.0 1e-15 57.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC95602.1 - 0.0041 16.9 0.0 0.58 10.1 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EMC95602.1 - 0.0062 16.6 0.1 8.9 6.5 0.0 3.7 3 1 0 3 3 3 1 Limkain b1 PknH_C PF14032.6 EMC95602.1 - 0.014 15.2 0.3 25 4.7 0.1 3.1 3 0 0 3 3 3 0 PknH-like extracellular domain RRM_9 PF18444.1 EMC95602.1 - 0.027 14.3 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 EMC95602.1 - 0.061 12.9 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMEM43 PF07787.12 EMC95602.1 - 0.16 11.3 1.4 0.27 10.6 1.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 CSN8_PSD8_EIF3K PF10075.9 EMC95606.1 - 6.8e-18 65.0 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EMC95606.1 - 0.00063 19.2 0.0 0.00085 18.8 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family RepA_N PF06970.11 EMC95606.1 - 0.17 11.9 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus CorA PF01544.18 EMC95607.1 - 0.0019 17.6 0.1 0.0051 16.2 0.1 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein E3_UbLigase_R4 PF13764.6 EMC95607.1 - 0.23 9.6 0.0 0.35 9.0 0.0 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Methyltransf_31 PF13847.6 EMC95608.1 - 3.5e-13 49.6 0.0 6.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC95608.1 - 9.2e-12 45.1 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC95608.1 - 9.6e-12 45.5 0.0 2.5e-11 44.1 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC95608.1 - 4.2e-11 43.4 0.0 7.8e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC95608.1 - 4.1e-10 40.2 0.0 7.3e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC95608.1 - 5.8e-07 29.1 0.0 8.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMC95608.1 - 0.0002 20.8 0.0 0.00031 20.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EMC95608.1 - 0.00024 20.9 0.0 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 EMC95608.1 - 0.00094 18.3 0.0 0.0017 17.5 0.0 1.3 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 EMC95608.1 - 0.0021 17.6 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EMC95608.1 - 0.0055 16.1 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EMC95608.1 - 0.017 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MetW PF07021.12 EMC95608.1 - 0.049 13.2 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EMC95608.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 EMC95609.1 - 2.4e-29 102.4 0.0 5.1e-29 101.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 UCR_14kD PF02271.16 EMC95610.1 - 0.05 13.6 0.3 0.14 12.1 0.3 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Ribosomal_L11_N PF03946.14 EMC95611.1 - 4.7e-26 90.4 0.1 9.2e-26 89.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EMC95611.1 - 4.4e-22 78.4 4.2 2e-21 76.3 4.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Fungal_trans PF04082.18 EMC95612.1 - 9e-10 38.0 0.1 2.1e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC95612.1 - 7.5e-06 26.0 13.3 1.5e-05 25.0 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAT PF02184.16 EMC95612.1 - 0.084 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat Vps39_2 PF10367.9 EMC95612.1 - 0.22 12.0 1.7 0.57 10.6 1.7 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 FRQ PF09421.10 EMC95613.1 - 1.2e-124 417.5 34.3 2.3e-123 413.2 34.3 2.3 1 1 0 1 1 1 1 Frequency clock protein Herpes_BLRF2 PF05812.12 EMC95613.1 - 0.027 14.6 0.2 0.1 12.7 0.2 2.0 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Patatin PF01734.22 EMC95615.1 - 1.6e-20 74.2 0.0 1.6e-10 41.5 0.0 2.3 2 0 0 2 2 2 2 Patatin-like phospholipase Epimerase PF01370.21 EMC95616.1 - 2e-16 60.2 0.2 4e-16 59.2 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC95616.1 - 4e-09 36.6 0.5 1.6e-08 34.6 0.5 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC95616.1 - 1.7e-07 31.1 0.2 3.4e-07 30.1 0.2 1.5 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EMC95616.1 - 4e-06 26.0 0.0 5.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMC95616.1 - 6.8e-06 25.7 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMC95616.1 - 1.1e-05 24.8 0.1 1.6e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EMC95616.1 - 0.0023 17.4 0.7 0.033 13.6 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EMC95616.1 - 0.11 11.5 0.1 0.6 9.1 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain MFS_1 PF07690.16 EMC95617.1 - 7.7e-21 74.4 62.7 6.2e-20 71.4 47.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EMC95618.1 - 2.2e-40 138.7 0.0 4.2e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC95618.1 - 1.1e-24 87.2 0.0 1.8e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Vac7 PF12751.7 EMC95619.1 - 1.1e-145 485.9 6.9 1.1e-145 485.9 6.9 2.4 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 DNA_methylase PF00145.17 EMC95620.1 - 1.5e-33 116.6 0.0 3.2e-33 115.5 0.0 1.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EMC95620.1 - 1.7e-05 24.7 0.0 0.23 11.3 0.0 2.6 2 0 0 2 2 2 2 BAH domain DUF2564 PF10819.8 EMC95621.1 - 3.3 8.2 7.0 1.3 9.5 1.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) Sugar_tr PF00083.24 EMC95622.1 - 1e-79 268.5 27.4 1.3e-79 268.2 27.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC95622.1 - 1e-12 47.7 46.9 4.1e-12 45.7 23.7 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily S-AdoMet_synt_C PF02773.16 EMC95623.1 - 3.4e-65 218.2 0.2 7.9e-65 217.0 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EMC95623.1 - 1e-44 151.6 0.0 2.2e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EMC95623.1 - 1.6e-43 147.4 0.6 3.2e-43 146.4 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EMC95623.1 - 0.061 12.1 0.1 1.1 8.0 0.0 2.2 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) WD40 PF00400.32 EMC95624.1 - 1.5e-08 35.1 0.2 0.68 10.9 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Cu_amine_oxid PF01179.20 EMC95625.1 - 1.3e-162 541.4 0.0 1.6e-162 541.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EMC95625.1 - 3.2e-06 27.3 0.1 7.8e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 EMC95625.1 - 0.00017 21.9 0.0 0.00047 20.5 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans_2 PF11951.8 EMC95626.1 - 6e-55 186.6 2.0 8.2e-55 186.2 2.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC95626.1 - 1.1e-09 38.2 12.5 1.8e-09 37.5 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 EMC95626.1 - 0.044 13.7 4.1 0.097 12.6 4.1 1.6 1 0 0 1 1 1 0 AT hook motif DUF3824 PF12868.7 EMC95628.1 - 1.3e-19 71.4 34.2 1.3e-19 71.4 34.2 10.3 4 2 6 10 10 10 3 Domain of unknwon function (DUF3824) TraE PF05309.11 EMC95628.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 TraE protein DUF2721 PF11026.8 EMC95628.1 - 0.3 11.0 0.2 1.2 9.0 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Ribosomal_L27A PF00828.19 EMC95630.1 - 8.4e-21 75.0 0.0 1.1e-20 74.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PPR_3 PF13812.6 EMC95631.1 - 9.9e-09 35.2 0.0 0.13 12.4 0.0 4.5 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EMC95631.1 - 1.2e-05 25.4 0.0 4.9 7.4 0.0 5.4 5 1 1 6 6 6 3 PPR repeat family PPR PF01535.20 EMC95631.1 - 0.00019 21.4 0.5 1.5 9.3 0.0 5.5 6 0 0 6 6 6 1 PPR repeat TPR_14 PF13428.6 EMC95631.1 - 0.11 13.4 5.9 9.1 7.4 0.3 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 EMC95632.1 - 3.1e-13 49.7 0.7 2.5e-12 46.8 0.0 2.7 4 0 0 4 4 4 1 Ribosomal protein S18 DUF1686 PF07937.11 EMC95634.1 - 0.015 15.2 0.8 0.14 12.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1686) LapA_dom PF06305.11 EMC95634.1 - 0.17 11.7 0.4 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Gti1_Pac2 PF09729.9 EMC95636.1 - 1.2e-45 155.8 0.7 3.7e-38 131.4 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Cnd1_N PF12922.7 EMC95637.1 - 9.6e-57 191.4 0.4 9.6e-57 191.4 0.4 2.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EMC95637.1 - 1.1e-48 165.4 1.6 1.2e-42 145.7 0.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMC95637.1 - 1.2e-10 41.6 2.5 0.016 15.6 0.1 5.5 4 1 0 5 5 5 2 HEAT repeats RTP1_C1 PF10363.9 EMC95637.1 - 5.8e-06 26.5 0.1 0.14 12.3 0.0 4.1 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EMC95637.1 - 2.7e-05 24.0 10.4 0.43 11.0 0.0 7.4 8 0 0 8 8 8 1 HEAT repeat Adaptin_N PF01602.20 EMC95637.1 - 0.0085 14.7 4.8 0.08 11.5 0.3 3.9 3 2 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 EMC95637.1 - 0.031 13.8 0.1 1.1 8.8 0.0 3.0 2 1 0 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.6 EMC95637.1 - 0.12 12.9 8.5 72 4.0 0.0 5.8 6 0 0 6 6 6 0 HEAT-like repeat Cnd3 PF12719.7 EMC95637.1 - 0.21 10.7 4.7 0.81 8.8 0.1 3.4 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.25 EMC95638.1 - 3.3e-45 154.5 0.0 9.5e-23 80.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EMC95638.1 - 1.6e-13 50.6 0.0 6.1e-10 38.8 0.0 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EMC95638.1 - 0.00018 21.5 0.0 0.67 9.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMC95638.1 - 0.0013 17.6 0.0 0.0022 16.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EMC95638.1 - 0.032 13.6 0.0 0.086 12.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CVNH PF08881.10 EMC95639.1 - 4.4e-24 85.1 0.2 4.9e-24 85.0 0.2 1.0 1 0 0 1 1 1 1 CVNH domain baeRF_family11 PF18855.1 EMC95640.1 - 0.033 14.5 0.0 0.052 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 Pyrid_ox_like PF16242.5 EMC95641.1 - 2.3e-26 92.2 0.0 3.5e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EMC95641.1 - 2.9e-10 40.2 0.0 5.9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EMP70 PF02990.16 EMC95642.1 - 7.4e-204 678.2 1.8 1e-203 677.8 1.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 bHLH-MYC_N PF14215.6 EMC95642.1 - 0.19 12.0 0.3 0.34 11.2 0.3 1.3 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Sof1 PF04158.14 EMC95643.1 - 1.1e-29 102.5 14.5 1.9e-29 101.8 14.5 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EMC95643.1 - 1.4e-28 98.6 5.6 3.1e-06 27.8 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC95643.1 - 6.7e-12 45.6 0.1 0.0027 18.0 0.1 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMC95643.1 - 0.0051 15.8 0.0 0.026 13.5 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_1 PF00036.32 EMC95645.1 - 4e-25 85.4 9.2 2.3e-08 33.0 0.2 5.1 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EMC95645.1 - 9.7e-24 81.2 4.3 3.4e-05 23.4 0.0 5.3 5 1 1 6 6 6 4 EF-hand domain EF-hand_7 PF13499.6 EMC95645.1 - 5.1e-23 81.3 5.6 1.5e-14 54.2 0.8 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EMC95645.1 - 7.6e-17 60.0 10.7 4.2e-05 22.8 0.1 5.4 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 EMC95645.1 - 3.3e-16 58.9 6.5 8.8e-06 25.5 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 EMC95645.1 - 1.4e-08 34.6 4.1 0.0053 16.7 0.2 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EMC95645.1 - 0.00017 21.8 0.5 0.031 14.6 0.1 3.6 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EMC95645.1 - 0.0014 18.9 1.8 1.7 9.0 0.3 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EMC95645.1 - 0.03 14.2 1.5 0.5 10.3 0.1 3.2 4 0 0 4 4 4 0 EF hand Staphylokinase PF02821.16 EMC95645.1 - 0.055 13.9 0.0 14 6.1 0.0 2.5 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family DUF4485 PF14846.6 EMC95647.1 - 0.0034 17.4 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) Rhodanese PF00581.20 EMC95648.1 - 8.5e-13 48.8 0.0 1.7e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain ORC6 PF05460.13 EMC95648.1 - 0.61 9.3 2.8 1.2 8.3 2.8 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DNA_pol_phi PF04931.13 EMC95650.1 - 2.5e-149 498.8 0.6 3.2e-149 498.4 0.6 1.0 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 EMC95650.1 - 0.12 11.8 18.7 0.21 11.0 18.7 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EMC95650.1 - 2.8 6.0 12.0 5.7 5.0 12.0 1.5 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EMC95650.1 - 4.7 6.4 11.7 7.6 5.7 11.7 1.3 1 0 0 1 1 1 0 BUD22 RPN6_N PF18055.1 EMC95651.1 - 9.9e-45 151.7 1.3 1.8e-44 150.8 0.2 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EMC95651.1 - 5.1e-21 75.1 1.1 2.4e-20 73.0 0.4 2.3 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EMC95651.1 - 1.2e-10 40.9 0.2 3e-10 39.7 0.2 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 EMC95651.1 - 0.00047 19.6 3.5 0.00079 18.9 1.7 2.2 1 1 1 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 EMC95651.1 - 0.00053 19.6 0.4 0.0012 18.5 0.4 1.6 1 0 0 1 1 1 1 DDRGK domain NepR PF18557.1 EMC95651.1 - 0.0054 16.3 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 Anti-sigma factor NepR DUF3496 PF12001.8 EMC95651.1 - 0.13 12.7 0.5 0.97 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) TPR_7 PF13176.6 EMC95651.1 - 2 8.6 8.3 24 5.3 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat FliS PF02561.14 EMC95651.1 - 4.8 7.5 8.6 2.9 8.2 0.3 3.8 5 0 0 5 5 5 0 Flagellar protein FliS SNF2_N PF00176.23 EMC95652.1 - 5.2e-21 74.7 0.0 2e-20 72.9 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 EMC95652.1 - 3.2e-18 66.2 0.0 9.4e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 EMC95652.1 - 1e-10 41.9 0.2 3e-10 40.4 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EMC95652.1 - 0.00064 19.5 0.6 0.00064 19.5 0.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EMC95652.1 - 0.098 12.7 0.2 12 5.8 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit zf-RING_4 PF14570.6 EMC95652.1 - 0.1 12.4 14.1 0.039 13.7 2.3 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 EMC95652.1 - 0.25 11.3 14.2 0.075 12.9 3.0 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC95652.1 - 0.45 10.4 14.2 0.056 13.3 7.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EMC95652.1 - 1.3 9.1 12.7 0.23 11.5 2.5 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 EMC95652.1 - 1.4 9.3 19.0 0.055 13.8 4.7 2.9 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 EMC95652.1 - 2.3 8.3 23.0 0.71 9.9 9.5 2.8 2 0 0 2 2 2 0 zinc-RING finger domain Gar1 PF04410.14 EMC95654.1 - 1.3e-21 77.0 0.5 1.4e-21 76.9 0.5 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.17 EMC95655.1 - 8e-87 292.2 18.4 9.3e-87 291.9 18.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3445 PF11927.8 EMC95656.1 - 2.8e-77 259.4 0.0 3.5e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Exo5 PF09810.9 EMC95657.1 - 6.9e-133 443.7 0.0 8.3e-133 443.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EMC95657.1 - 0.00014 21.8 0.0 0.1 12.5 0.0 2.7 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.12 EMC95658.1 - 3.9e-15 55.8 0.5 8.8e-15 54.7 0.5 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Histone PF00125.24 EMC95659.1 - 4e-52 176.0 2.5 4.5e-52 175.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EMC95659.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EMC95659.1 - 4e-05 24.2 1.2 4.7e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EMC95659.1 - 4.3e-05 23.6 0.4 7.4e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EMC95659.1 - 0.0038 17.5 0.4 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EMC95659.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EMC95660.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EMC95660.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EMC95660.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EMC95660.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EMC95660.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EMC95660.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EMC95660.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EMC95660.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EMC95660.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region HAD_2 PF13419.6 EMC95661.1 - 3.5e-11 43.5 0.0 1.2e-10 41.7 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMC95661.1 - 1.1e-07 32.4 0.0 2.5e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC95661.1 - 2.6e-05 24.2 0.0 6.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF5642 PF18702.1 EMC95661.1 - 0.041 13.6 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5642) DUF442 PF04273.13 EMC95661.1 - 0.19 11.8 0.0 0.79 9.8 0.0 2.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) MFS_1 PF07690.16 EMC95662.1 - 1.9e-36 125.7 18.5 1.9e-36 125.7 18.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC95662.1 - 6.7e-07 28.5 6.1 6.7e-07 28.5 6.1 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EMC95662.1 - 0.00026 19.6 2.5 0.0004 19.0 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OSTbeta PF15048.6 EMC95662.1 - 0.18 12.0 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Corona_S2 PF01601.16 EMC95662.1 - 0.22 10.0 2.7 0.37 9.2 2.7 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Phage_holin_2_4 PF16082.5 EMC95662.1 - 1.1 9.0 3.7 2.4 7.9 0.0 3.1 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like OATP PF03137.20 EMC95662.1 - 1.9 6.7 6.0 9.2 4.4 6.0 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ras PF00071.22 EMC95664.1 - 1.1e-51 174.7 0.2 5.7e-51 172.3 0.2 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EMC95664.1 - 3.6e-18 65.9 0.0 8.8e-17 61.4 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC95664.1 - 0.00014 21.4 0.0 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMC95664.1 - 0.0064 16.1 0.1 1.6 8.2 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Septin PF00735.18 EMC95664.1 - 0.052 12.8 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 EMC95664.1 - 0.061 13.2 0.1 9.4 6.1 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 EMC95664.1 - 0.069 12.7 0.1 1.1 8.8 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 EMC95664.1 - 0.13 12.7 0.1 0.2 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain SWI-SNF_Ssr4 PF08549.10 EMC95667.1 - 4.7e-146 488.4 9.3 5.3e-146 488.2 9.3 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Abhydrolase_6 PF12697.7 EMC95671.1 - 3.9e-19 70.1 0.0 4.5e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydantoinase_A PF01968.18 EMC95671.1 - 0.076 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Radical_SAM PF04055.21 EMC95671.1 - 0.1 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily PC4 PF02229.16 EMC95672.1 - 1.5e-20 72.5 0.0 4e-20 71.2 0.1 1.7 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) adh_short_C2 PF13561.6 EMC95673.1 - 7.3e-39 133.7 0.0 9.6e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC95673.1 - 2.3e-35 121.8 0.0 3.4e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC95673.1 - 8.9e-09 35.5 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Mitovir_RNA_pol PF05919.11 EMC95673.1 - 0.18 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase BRCT_2 PF16589.5 EMC95674.1 - 3.5e-16 59.4 0.0 5.6e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EMC95674.1 - 0.00051 20.4 0.0 0.00098 19.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EMC95674.1 - 0.00052 19.9 0.2 0.0012 18.7 0.0 1.7 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 EMC95674.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain MFS_1 PF07690.16 EMC95675.1 - 6.1e-30 104.3 56.1 4.2e-17 62.1 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC95675.1 - 5.6e-06 25.5 37.8 0.0013 17.7 15.1 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter Transgly_assoc PF04226.13 EMC95675.1 - 6.1 7.2 18.0 0.48 10.7 0.4 4.8 4 0 0 4 4 4 0 Transglycosylase associated protein 2OG-FeII_Oxy_2 PF13532.6 EMC95676.1 - 2.8e-37 128.8 0.0 3.7e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EMC95676.1 - 0.00053 20.0 4.6 0.00091 19.3 4.6 1.4 1 0 0 1 1 1 1 GRF zinc finger 2Fe-2S_thioredx PF01257.19 EMC95680.1 - 9.1e-62 207.2 0.2 1.2e-61 206.9 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DctP PF03480.13 EMC95680.1 - 0.14 11.4 0.0 0.6 9.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 F-box-like_2 PF13013.6 EMC95681.1 - 0.096 12.7 0.0 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 F-box-like domain ABC_membrane PF00664.23 EMC95682.1 - 3.5e-38 131.8 12.6 4.4e-38 131.5 12.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMC95682.1 - 3.9e-34 118.1 0.0 7.7e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMC95682.1 - 1.1e-05 25.0 0.0 0.002 17.6 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMC95682.1 - 0.00014 22.3 0.0 0.00032 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EMC95682.1 - 0.00098 19.0 1.6 0.0063 16.4 0.0 2.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EMC95682.1 - 0.001 19.3 0.0 0.0043 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EMC95682.1 - 0.0068 16.1 0.1 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EMC95682.1 - 0.0085 16.5 0.0 0.069 13.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EMC95682.1 - 0.009 16.0 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMC95682.1 - 0.014 15.1 0.1 0.038 13.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EMC95682.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EMC95682.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 EMC95682.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 EMC95682.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 EMC95682.1 - 0.034 14.7 0.0 0.091 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMC95682.1 - 0.062 13.4 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EMC95682.1 - 0.08 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EMC95682.1 - 0.082 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EMC95682.1 - 0.1 11.8 0.0 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 EMC95682.1 - 0.18 11.0 0.0 0.36 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain WD40 PF00400.32 EMC95683.1 - 8.1e-14 51.8 17.6 0.015 16.1 0.8 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat TMEM154 PF15102.6 EMC95684.1 - 1.2e-05 25.3 0.2 1.2e-05 25.3 0.2 2.5 1 1 1 2 2 1 1 TMEM154 protein family Mid2 PF04478.12 EMC95684.1 - 0.0013 18.6 0.4 0.0013 18.6 0.4 2.2 1 1 0 2 2 1 1 Mid2 like cell wall stress sensor Apt1 PF10351.9 EMC95684.1 - 0.0049 15.8 8.7 0.0089 14.9 8.7 1.5 1 0 0 1 1 1 1 Golgi-body localisation protein domain Macoilin PF09726.9 EMC95684.1 - 0.0067 15.1 9.2 0.0098 14.5 9.2 1.3 1 0 0 1 1 1 1 Macoilin family SKG6 PF08693.10 EMC95684.1 - 0.0087 15.4 0.0 0.0087 15.4 0.0 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF2407_C PF13373.6 EMC95684.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.5 1 1 0 1 1 1 0 DUF2407 C-terminal domain DUF2723 PF11028.8 EMC95684.1 - 0.02 14.8 1.3 0.036 14.0 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) RIFIN PF02009.16 EMC95684.1 - 0.045 13.7 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Rifin Presenilin PF01080.17 EMC95684.1 - 0.15 10.8 5.1 0.22 10.2 5.1 1.2 1 0 0 1 1 1 0 Presenilin Stevor PF17410.2 EMC95684.1 - 1.1 8.8 2.7 1.8 8.0 2.7 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SMYLE_N PF18615.1 EMC95684.1 - 2 7.9 10.3 2.9 7.4 10.3 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Utp14 PF04615.13 EMC95684.1 - 5.5 5.4 6.4 7.3 5.0 6.4 1.1 1 0 0 1 1 1 0 Utp14 protein Tmemb_cc2 PF10267.9 EMC95684.1 - 7.1 5.7 14.3 11 5.1 14.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PRP3 PF08572.10 EMC95685.1 - 7.1e-64 215.6 10.3 7.1e-64 215.6 10.3 2.2 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EMC95685.1 - 1.4e-46 158.3 0.1 1.4e-46 158.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PARM PF17061.5 EMC95685.1 - 2.7 8.0 7.3 5.7 7.0 7.3 1.5 1 0 0 1 1 1 0 PARM GET2 PF08690.10 EMC95685.1 - 3 7.4 13.2 0.12 12.0 4.7 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 PhzC-PhzF PF02567.16 EMC95686.1 - 9.4e-42 143.4 0.0 1.1e-41 143.2 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Inp1 PF12634.7 EMC95687.1 - 3.8e-40 137.1 0.0 1.4e-39 135.2 0.0 1.9 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 Trypan_PARP PF05887.11 EMC95687.1 - 0.78 9.7 12.0 0.029 14.3 3.9 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) EI24 PF07264.11 EMC95688.1 - 6.4e-13 49.3 0.2 1.3e-05 25.5 1.0 2.3 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) zf-C2H2 PF00096.26 EMC95689.1 - 7.7e-11 41.8 15.7 4.3e-06 26.9 1.5 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC95689.1 - 2.6e-10 40.3 4.3 1.3e-05 25.4 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC95689.1 - 1.2e-07 31.9 12.4 0.0004 21.0 1.1 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMC95689.1 - 0.00015 21.9 0.9 0.00015 21.9 0.9 4.1 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EMC95689.1 - 0.011 15.7 3.1 0.049 13.7 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EMC95689.1 - 0.012 16.0 5.9 0.034 14.5 0.3 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 EMC95689.1 - 0.061 13.4 0.4 0.85 9.8 0.2 2.5 1 1 1 2 2 2 0 Zic proteins zinc finger domain zf-C2HE PF16278.5 EMC95689.1 - 0.11 13.0 0.7 0.4 11.2 0.7 2.0 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 EMC95689.1 - 0.17 11.7 3.6 8.8 6.2 0.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 EMC95689.1 - 1.9 8.3 9.6 0.13 12.0 1.0 3.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain PAP2_3 PF14378.6 EMC95690.1 - 8.2e-24 84.3 15.5 8.2e-24 84.3 15.5 1.7 1 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EMC95690.1 - 2.6e-11 43.4 4.2 2.6e-11 43.4 4.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily DUF4452 PF14618.6 EMC95690.1 - 0.02 14.8 0.4 0.042 13.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) CYSTM PF12734.7 EMC95691.1 - 2.9e-10 40.3 17.5 2.9e-10 40.3 17.5 4.4 2 2 1 3 3 3 2 Cysteine-rich TM module stress tolerance Ribosomal_L18 PF17135.4 EMC95692.1 - 2.6e-90 300.8 0.5 2.9e-90 300.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EMC95692.1 - 0.00074 20.2 0.3 0.00074 20.2 0.3 2.7 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A BDM PF10684.9 EMC95692.1 - 0.15 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein Ribosomal_L7Ae PF01248.26 EMC95693.1 - 2.2e-23 81.8 0.0 2.5e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peptidase_S68 PF10461.9 EMC95693.1 - 0.33 11.2 1.0 0.59 10.4 0.1 1.8 2 0 0 2 2 2 0 Peptidase S68 Ribosomal_L16 PF00252.18 EMC95694.1 - 3.7e-16 59.3 0.1 4.4e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Arylsulfotran_2 PF14269.6 EMC95695.1 - 1.3e-54 185.7 2.8 1.1e-46 159.6 0.4 2.2 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMC95695.1 - 6.9e-15 54.8 4.1 1.5e-14 53.8 2.6 2.1 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) Hexapep_2 PF14602.6 EMC95695.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase ThiF PF00899.21 EMC95696.1 - 8.4e-56 189.0 0.0 1.5e-55 188.2 0.0 1.4 1 1 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EMC95696.1 - 1.3e-07 32.1 0.0 3.1e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 EMC95696.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EMC95696.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EMC95696.1 - 0.17 11.1 0.1 0.34 10.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 EMC95697.1 - 2.1e-51 175.1 0.3 2.4e-51 174.9 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hydantoinase_B PF02538.14 EMC95698.1 - 2.3e-221 735.7 0.2 3.2e-221 735.2 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EMC95698.1 - 9.5e-102 340.2 0.6 2.4e-101 338.9 0.6 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EMC95698.1 - 2.1e-62 210.0 1.0 5.5e-61 205.4 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DuoxA PF10204.9 EMC95699.1 - 0.0051 15.9 0.9 0.0085 15.1 0.1 1.7 1 1 1 2 2 2 1 Dual oxidase maturation factor Abhydrolase_6 PF12697.7 EMC95700.1 - 6.2e-09 36.8 1.4 6.2e-09 36.8 1.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC95700.1 - 1.1e-08 34.7 0.1 2.7e-08 33.4 0.1 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMC95700.1 - 0.00012 21.9 0.1 0.00019 21.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B_6 PF16661.5 EMC95701.1 - 2.7e-60 203.1 0.0 4.2e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EMC95701.1 - 7.8e-44 149.8 8.3 9e-44 149.6 0.6 2.6 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EMC95701.1 - 3e-18 66.1 0.0 2.4e-17 63.2 0.0 2.5 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EMC95701.1 - 3.2e-11 43.0 0.0 7.2e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EMC95701.1 - 0.0052 16.8 0.4 0.029 14.4 0.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPP1 PF10341.9 EMC95701.1 - 0.36 10.8 1.1 3.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD CSTF2_hinge PF14327.6 EMC95702.1 - 9.3e-32 109.3 4.3 2.6e-31 107.9 4.3 1.8 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EMC95702.1 - 2.5e-21 75.3 0.1 3.9e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EMC95702.1 - 2.2e-08 33.5 2.0 2.2e-08 33.5 2.0 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EMC95702.1 - 0.019 15.1 0.1 0.039 14.1 0.1 1.6 1 1 0 1 1 1 0 RNA recognition motif Alpha-amylase PF00128.24 EMC95703.1 - 6.2e-48 164.1 0.3 1.3e-47 163.0 0.3 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EMC95703.1 - 1.5e-27 95.7 0.7 3.4e-27 94.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) DUF2850 PF11012.8 EMC95703.1 - 0.0052 17.1 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2850) hDGE_amylase PF14701.6 EMC95703.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain RNA_pol_Rpb1_5 PF04998.17 EMC95705.1 - 1.7e-89 299.8 0.0 3.2e-89 298.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMC95705.1 - 6.5e-69 231.4 0.1 1.6e-68 230.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EMC95705.1 - 2.1e-30 105.7 0.0 5.8e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EMC95705.1 - 4.2e-29 101.9 0.2 8.1e-28 97.6 0.1 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EMC95705.1 - 1.3e-19 70.2 0.0 5.2e-19 68.2 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rav1p_C PF12234.8 EMC95705.1 - 0.052 12.0 0.0 0.084 11.3 0.0 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal HTH_54 PF18607.1 EMC95705.1 - 0.14 12.3 0.1 0.55 10.3 0.1 2.0 1 0 0 1 1 1 0 ParA helix turn helix domain peroxidase PF00141.23 EMC95707.1 - 4.9e-26 91.8 0.0 8.1e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase FSH1 PF03959.13 EMC95708.1 - 1.8e-31 109.5 0.0 2e-30 106.1 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EMC95708.1 - 4.8e-07 30.6 0.1 5.7e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PBP_N PF17093.5 EMC95708.1 - 0.0012 19.1 1.9 0.0017 18.6 0.0 2.1 2 0 0 2 2 2 1 Penicillin-binding protein N-terminus SR-25 PF10500.9 EMC95708.1 - 0.15 11.7 10.3 0.2 11.3 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Abhydrolase_2 PF02230.16 EMC95708.1 - 0.2 11.4 0.1 33 4.2 0.0 2.5 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EMC95709.1 - 1.9e-07 31.9 0.3 2.7e-07 31.4 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC95709.1 - 0.00056 19.3 0.0 0.00091 18.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SH3_9 PF14604.6 EMC95710.1 - 4.8e-10 39.1 0.0 8.5e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMC95710.1 - 9.2e-08 31.6 0.0 2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMC95710.1 - 1.8e-06 27.6 0.0 4.1e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain PCI PF01399.27 EMC95711.1 - 0.013 16.0 0.1 0.56 10.7 0.0 2.6 2 1 0 2 2 2 0 PCI domain ANAPC3 PF12895.7 EMC95711.1 - 0.029 14.6 2.4 0.045 14.0 1.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ppx-GppA PF02541.16 EMC95712.1 - 5.7e-42 144.1 0.0 7.7e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Rft-1 PF04506.13 EMC95714.1 - 5.3e-143 477.4 2.6 6.2e-143 477.2 2.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 EMC95714.1 - 0.00085 18.6 7.6 0.00085 18.6 7.6 3.7 2 2 0 3 3 3 2 Polysaccharide biosynthesis protein AIM24 PF01987.17 EMC95715.1 - 1.7e-46 158.5 0.0 2.3e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Acetyltransf_1 PF00583.25 EMC95716.1 - 2.8e-11 43.7 0.0 3.8e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC95716.1 - 6.6e-09 35.8 0.0 8.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC95716.1 - 7e-07 29.6 0.0 1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC95716.1 - 0.00015 21.7 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMC95716.1 - 0.00017 21.7 0.0 0.00037 20.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain STAS PF01740.21 EMC95716.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 STAS domain Acetyltransf_13 PF13880.6 EMC95716.1 - 0.058 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 EMC95716.1 - 0.079 13.1 0.1 0.19 11.8 0.1 1.7 2 1 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF2183 PF09949.9 EMC95717.1 - 1.2e-21 76.8 0.1 2.5e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Atg14 PF10186.9 EMC95718.1 - 2.2 7.3 15.1 3.9 6.5 15.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 EMC95718.1 - 2.7 8.3 6.9 1.3 9.3 0.5 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 P22_Tail-4 PF11650.8 EMC95719.1 - 0.042 13.8 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor Glyco_hydro_cc PF11790.8 EMC95721.1 - 1.5e-72 244.1 0.5 1.7e-72 243.9 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NAD_binding_1 PF00175.21 EMC95722.1 - 4.7e-25 88.3 0.0 8.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMC95722.1 - 7.4e-19 68.0 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EMC95722.1 - 4.4e-09 36.6 0.0 3.4e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain 2OG-FeII_Oxy PF03171.20 EMC95724.1 - 2.7e-14 53.4 0.0 5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMC95724.1 - 3.3e-13 50.4 0.0 6.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PRP1_N PF06424.12 EMC95725.1 - 8.9e-52 175.4 7.9 3.3e-51 173.6 7.9 2.1 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 EMC95725.1 - 9.8e-24 83.7 24.1 1e-08 35.5 0.4 10.6 7 3 3 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMC95725.1 - 1.4e-22 78.4 46.5 2e-05 25.0 0.4 14.7 6 4 10 16 16 15 9 Tetratricopeptide repeat TPR_16 PF13432.6 EMC95725.1 - 7.7e-14 52.1 20.2 2e-05 25.1 1.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 EMC95725.1 - 2.9e-12 45.7 17.6 0.86 9.9 0.0 11.7 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMC95725.1 - 5.9e-11 41.7 0.1 3.4 8.1 0.0 9.5 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMC95725.1 - 3e-09 36.6 8.1 3 8.4 0.0 11.2 11 2 0 11 11 11 1 Tetratricopeptide repeat TPR_9 PF13371.6 EMC95725.1 - 4.1e-06 26.9 9.9 0.098 12.8 0.1 6.0 4 2 1 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.8 EMC95725.1 - 8.8e-05 21.6 14.5 0.064 12.2 0.0 6.5 4 1 3 7 7 7 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 EMC95725.1 - 0.00012 21.7 8.4 0.54 10.2 0.0 7.4 9 0 0 9 9 8 1 Tetratricopeptide repeat Suf PF05843.14 EMC95725.1 - 0.00047 20.2 5.2 0.19 11.7 0.0 4.2 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EMC95725.1 - 0.005 16.1 8.0 0.005 16.1 8.0 6.2 3 2 1 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 EMC95725.1 - 0.0088 16.6 9.8 0.5 11.1 0.2 6.5 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMC95725.1 - 0.077 13.7 18.0 7.3 7.5 0.0 9.4 10 0 0 10 10 10 0 Tetratricopeptide repeat Cutinase PF01083.22 EMC95725.1 - 0.11 12.4 0.1 2.3 8.1 0.0 3.1 2 1 1 3 3 3 0 Cutinase GST_N_3 PF13417.6 EMC95726.1 - 5.1e-09 36.4 0.0 9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMC95726.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMC95726.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ADH_zinc_N PF00107.26 EMC95727.1 - 6.3e-25 87.7 1.8 7e-25 87.5 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC95727.1 - 1.6e-21 76.2 0.2 3.4e-21 75.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMC95727.1 - 0.012 16.7 0.0 0.022 15.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 EMC95727.1 - 0.051 13.0 1.3 0.22 11.0 0.4 2.2 1 1 0 2 2 2 0 short chain dehydrogenase Transp_cyt_pur PF02133.15 EMC95728.1 - 7.9e-94 314.9 41.8 9.3e-94 314.7 41.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Tyrosinase PF00264.20 EMC95731.1 - 1.4e-48 166.1 10.6 2.3e-48 165.4 10.6 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EMC95731.1 - 2.6e-30 105.6 0.0 4.5e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain TPT PF03151.16 EMC95732.1 - 1.7e-23 83.4 13.6 2.3e-23 83.0 13.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EMC95732.1 - 1.1e-06 28.9 33.0 0.0034 17.5 7.7 2.3 2 1 0 2 2 2 2 EamA-like transporter family RRM_1 PF00076.22 EMC95733.1 - 4.8e-11 42.3 0.0 6.9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMC95733.1 - 0.0023 17.9 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif NifU_N PF01592.16 EMC95734.1 - 7.6e-54 181.3 0.1 9.8e-54 180.9 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EMC95734.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 TSCPD domain Beta-lactamase PF00144.24 EMC95735.1 - 3.5e-43 148.1 0.6 5.2e-43 147.5 0.6 1.1 1 0 0 1 1 1 1 Beta-lactamase DOPA_dioxygen PF08883.11 EMC95736.1 - 2.5e-45 153.1 0.2 3.3e-45 152.7 0.2 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Amino_oxidase PF01593.24 EMC95737.1 - 1.7e-37 129.8 0.0 2.4e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMC95737.1 - 4.2e-16 58.9 0.0 2.6e-15 56.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC95737.1 - 2.4e-08 34.0 0.0 2.8e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMC95737.1 - 2.6e-05 23.6 0.0 4.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EMC95737.1 - 5e-05 23.8 0.0 0.019 15.5 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC95737.1 - 0.00042 19.6 0.0 0.0016 17.7 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EMC95737.1 - 0.0099 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 EMC95737.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sua5_yciO_yrdC PF01300.18 EMC95738.1 - 8.8e-50 168.7 0.0 1.6e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EMC95738.1 - 1e-31 110.3 0.0 1.6e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Peptidase_C15 PF01470.17 EMC95739.1 - 1.4e-11 45.0 0.0 8.8e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Pyroglutamyl peptidase MutS_V PF00488.21 EMC95740.1 - 2.5e-80 269.0 0.2 5.1e-80 268.0 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMC95740.1 - 6.9e-37 127.5 1.2 1.3e-36 126.6 0.3 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EMC95740.1 - 1.5e-22 80.4 0.1 6.1e-22 78.4 0.1 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EMC95740.1 - 8.5e-17 61.3 1.1 3.9e-16 59.2 1.1 2.3 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 EMC95740.1 - 3.5e-14 53.0 0.0 6.2e-13 49.0 0.0 2.5 2 0 0 2 2 2 1 MutS domain I ABC_tran_CTD PF16326.5 EMC95741.1 - 0.00023 21.3 3.2 0.00023 21.3 3.2 5.7 4 3 1 5 5 5 2 ABC transporter C-terminal domain HalX PF08663.10 EMC95741.1 - 0.017 15.4 2.5 0.017 15.4 2.5 5.8 4 1 2 6 6 6 0 HalX domain EzrA PF06160.12 EMC95741.1 - 0.38 8.9 36.3 0.013 13.7 8.0 3.0 2 1 0 3 3 3 0 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 EMC95741.1 - 5.6 6.3 56.7 1.6 8.1 21.4 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 EMC95741.1 - 6.1 6.9 8.3 42 4.2 0.2 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PQ-loop PF04193.14 EMC95742.1 - 2.9e-26 91.0 8.2 3.5e-18 65.1 2.8 2.7 2 1 0 2 2 2 2 PQ loop repeat Peptidase_U4 PF03419.13 EMC95742.1 - 0.084 12.2 7.3 0.14 11.5 7.2 1.7 1 1 0 1 1 1 0 Sporulation factor SpoIIGA VIT1 PF01988.19 EMC95742.1 - 7.7 6.3 10.5 1.5 8.6 2.4 2.3 1 1 1 2 2 2 0 VIT family Band_7 PF01145.25 EMC95744.1 - 9.8e-30 103.9 3.2 1.7e-29 103.1 3.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EMC95744.1 - 0.0042 16.8 0.1 0.0069 16.1 0.1 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Kinesin_assoc PF16183.5 EMC95744.1 - 0.48 10.6 3.6 0.65 10.1 2.4 1.7 1 1 1 2 2 2 0 Kinesin-associated SNF2_N PF00176.23 EMC95746.1 - 1.7e-57 194.7 0.0 2.7e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EMC95746.1 - 5.9e-54 183.0 0.0 1.8e-53 181.4 0.1 1.8 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 EMC95746.1 - 5.3e-16 59.0 0.0 1.6e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC95746.1 - 1.4e-06 28.4 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EMC95746.1 - 5.1e-06 25.9 0.0 0.00011 21.4 0.0 2.7 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Acetyltransf_7 PF13508.7 EMC95747.1 - 3.9e-06 27.2 0.0 5.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC95747.1 - 1.8e-05 25.0 0.0 2.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC95747.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DEAD_2 PF06733.15 EMC95749.1 - 3.2e-56 189.7 0.0 7.2e-56 188.6 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EMC95749.1 - 2.6e-49 167.5 1.9 1.6e-44 151.9 0.6 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EMC95749.1 - 2.3e-43 148.3 0.0 6.2e-43 146.9 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EMC95749.1 - 0.00017 21.7 0.0 0.0092 16.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMC95749.1 - 0.0018 18.1 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 EMC95749.1 - 0.14 11.6 0.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 EMC95749.1 - 0.14 10.9 0.0 2.8 6.5 0.0 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain zf-RING_2 PF13639.6 EMC95750.1 - 1.7e-08 34.6 7.7 4e-08 33.4 7.7 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EMC95750.1 - 3.1e-05 24.1 5.6 6.6e-05 23.0 5.6 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EMC95750.1 - 4.3e-05 23.5 2.2 0.0001 22.3 2.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EMC95750.1 - 0.00029 21.1 6.8 0.0007 19.8 6.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 EMC95750.1 - 0.0029 17.7 5.8 0.0087 16.2 5.8 1.9 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.25 EMC95750.1 - 0.0037 17.1 8.4 0.0073 16.2 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EMC95750.1 - 0.0041 16.7 5.6 0.0098 15.5 5.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 EMC95750.1 - 0.007 16.2 3.0 0.007 16.2 3.0 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 EMC95750.1 - 0.035 13.9 7.7 0.08 12.8 7.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1400 PF07176.11 EMC95750.1 - 0.075 13.3 3.6 0.13 12.5 0.3 3.2 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) Maf_N PF08383.11 EMC95750.1 - 0.1 12.4 0.9 0.25 11.1 0.0 2.2 2 0 0 2 2 1 0 Maf N-terminal region zf-RING-like PF08746.11 EMC95750.1 - 0.11 12.8 6.8 0.26 11.6 6.8 1.7 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 EMC95750.1 - 0.2 11.6 5.8 0.41 10.6 5.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 EMC95750.1 - 0.2 11.5 5.7 0.42 10.5 5.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 EMC95750.1 - 0.35 11.0 3.3 1.4 9.0 3.3 2.1 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_9 PF13901.6 EMC95750.1 - 0.97 9.4 6.1 3.3 7.6 6.1 1.9 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_4 PF14570.6 EMC95750.1 - 3.2 7.6 4.7 23 4.9 4.7 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Med27 PF11571.8 EMC95750.1 - 9.4 6.7 8.0 3 8.2 3.9 2.4 2 0 0 2 2 1 0 Mediator complex subunit 27 3HCDH_N PF02737.18 EMC95751.1 - 1.7e-39 135.6 0.0 2.6e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EMC95751.1 - 5.7e-12 46.1 0.0 1.5e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DAO PF01266.24 EMC95751.1 - 0.001 18.7 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ldh_1_N PF00056.23 EMC95751.1 - 0.0028 17.8 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EMC95751.1 - 0.0033 16.7 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC95751.1 - 0.0083 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EMC95751.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EMC95751.1 - 0.05 13.0 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-ANAPC11 PF12861.7 EMC95752.1 - 0.01 15.9 6.4 3.7 7.7 0.1 4.8 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1ORF64 PF15547.6 EMC95753.1 - 0.025 15.1 1.9 0.24 11.8 0.9 2.8 1 1 1 2 2 2 0 Steroid receptor-associated and regulated protein Peptidase_S51 PF03575.17 EMC95753.1 - 5.8 6.5 7.5 0.45 10.1 1.6 2.2 2 0 0 2 2 2 0 Peptidase family S51 AMP-binding PF00501.28 EMC95754.1 - 7.9e-83 278.4 0.1 1e-82 278.0 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC95754.1 - 2.7e-15 57.1 0.3 7.4e-15 55.7 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DSBA PF01323.20 EMC95755.1 - 1.8e-39 135.5 0.0 2.1e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EMC95755.1 - 0.00078 19.6 0.0 0.0075 16.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 EMC95755.1 - 0.019 15.0 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_5 PF13743.6 EMC95755.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Lipocalin_5 PF13924.6 EMC95756.1 - 1.1e-23 83.6 0.0 1.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain WD40 PF00400.32 EMC95757.1 - 0.064 14.1 0.3 24 6.0 0.0 4.1 3 0 0 3 3 3 0 WD domain, G-beta repeat VID27 PF08553.10 EMC95758.1 - 3.2e-190 631.7 0.0 4.4e-190 631.2 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EMC95758.1 - 1.1e-70 237.0 0.0 1.1e-70 237.0 0.0 2.7 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EMC95758.1 - 5.5e-48 161.8 2.7 5.5e-48 161.8 2.7 1.8 2 0 0 2 2 2 1 VID27 PH-like domain DUF4221 PF13970.6 EMC95758.1 - 0.089 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) Nop14 PF04147.12 EMC95758.1 - 1.5 7.0 10.8 2.2 6.4 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2 PF00096.26 EMC95759.1 - 1.3e-05 25.4 11.9 0.004 17.5 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC95759.1 - 0.00027 21.2 3.8 0.00027 21.2 3.8 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC95759.1 - 0.0011 19.6 11.5 0.072 14.0 2.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 EMC95759.1 - 0.24 10.6 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 EMC95759.1 - 1.3 8.8 5.6 2.4 8.0 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Coatomer_WDAD PF04053.14 EMC95760.1 - 4.6e-143 477.5 0.0 8.2e-143 476.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EMC95760.1 - 2.2e-88 296.7 0.0 3.2e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EMC95760.1 - 1.4e-35 120.7 17.3 6e-08 33.2 0.4 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC95760.1 - 2e-07 31.2 0.8 0.039 14.3 0.0 5.6 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC95760.1 - 0.024 13.3 7.1 2.7 6.6 0.1 4.0 2 1 1 4 4 4 0 Nucleoporin Nup120/160 STIMATE PF12400.8 EMC95761.1 - 1.2e-39 135.7 2.5 1.2e-39 135.7 2.5 1.8 2 0 0 2 2 2 1 STIMATE family FKBP_C PF00254.28 EMC95761.1 - 1.4e-30 105.5 0.0 2.1e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Zn_clus PF00172.18 EMC95763.1 - 1.4e-08 34.8 10.6 2.3e-08 34.0 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.21 EMC95766.1 - 7.8e-41 139.5 3.4 7.8e-41 139.5 3.4 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Laminin_G_2 PF02210.24 EMC95766.1 - 0.027 15.1 0.1 0.048 14.3 0.1 1.4 1 0 0 1 1 1 0 Laminin G domain Aldedh PF00171.22 EMC95767.1 - 1.1e-11 43.9 5.7 1.9e-10 39.8 4.0 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMC95767.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Glyco_hydro_20 PF00728.22 EMC95768.1 - 2.6e-83 280.4 0.0 3.2e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EMC95768.1 - 3.5e-28 99.0 0.0 6e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EMC95768.1 - 1.5e-06 29.0 0.0 2.5e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 SIR2 PF02146.17 EMC95769.1 - 1.6e-57 194.2 0.0 2.1e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Sir2 family SnoaL_2 PF12680.7 EMC95770.1 - 0.00013 22.5 0.0 0.00029 21.4 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EMC95770.1 - 0.0025 17.6 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.18 EMC95770.1 - 0.0032 17.1 0.0 0.077 12.5 0.0 2.2 1 1 1 2 2 2 1 Dienelactone hydrolase family Ank_4 PF13637.6 EMC95771.1 - 0.0016 18.9 0.5 1.1 9.9 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMC95771.1 - 0.0063 17.1 0.1 0.097 13.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) MBOAT PF03062.19 EMC95772.1 - 3.5e-43 148.3 15.0 3.5e-43 148.3 15.0 2.4 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EMC95772.1 - 2.6e-06 27.6 4.3 7.6e-06 26.1 4.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SurE PF01975.17 EMC95773.1 - 4e-33 114.8 0.0 5.2e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE FSH1 PF03959.13 EMC95774.1 - 1.1e-36 126.5 0.0 1.4e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EMC95774.1 - 0.13 11.5 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SHMT PF00464.19 EMC95775.1 - 6.1e-192 637.6 0.0 7.1e-192 637.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EMC95775.1 - 0.0045 16.3 0.0 0.079 12.2 0.0 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase DUF2390 PF09523.10 EMC95776.1 - 0.071 13.4 1.8 0.42 11.0 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) MAD PF05557.13 EMC95777.1 - 7.7e-53 179.9 53.4 1.7e-52 178.8 53.4 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein DUF2353 PF09789.9 EMC95777.1 - 0.0051 16.2 17.9 0.0051 16.2 17.9 4.8 1 1 3 4 4 4 1 Uncharacterized coiled-coil protein (DUF2353) ADIP PF11559.8 EMC95777.1 - 0.013 15.6 5.3 0.013 15.6 5.3 6.9 4 2 2 7 7 7 0 Afadin- and alpha -actinin-Binding Cep57_MT_bd PF06657.13 EMC95777.1 - 0.017 15.5 0.7 0.017 15.5 0.7 6.9 6 2 1 7 7 7 0 Centrosome microtubule-binding domain of Cep57 Fzo_mitofusin PF04799.13 EMC95777.1 - 0.021 14.4 0.6 0.021 14.4 0.6 6.1 4 2 4 8 8 8 0 fzo-like conserved region DUF16 PF01519.16 EMC95777.1 - 1.8 9.1 0.0 1.8 9.1 0.0 6.9 4 2 1 5 5 5 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 EMC95777.1 - 2.9 7.9 19.8 0.058 13.4 0.6 4.8 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup54_57_C PF18570.1 EMC95777.1 - 7.1 6.3 7.9 2.3 7.9 0.1 4.1 5 0 0 5 5 5 0 NUP57/Nup54 C-terminal domain Arginase PF00491.21 EMC95778.1 - 1.1e-74 251.4 0.3 1.3e-74 251.2 0.3 1.0 1 0 0 1 1 1 1 Arginase family WD40 PF00400.32 EMC95779.1 - 2e-35 120.2 29.4 0.00012 22.8 0.3 11.2 11 1 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC95779.1 - 6.2e-20 71.3 1.0 0.00042 20.6 0.0 7.2 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC95779.1 - 5.3e-05 22.1 0.0 0.033 12.8 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 EMC95779.1 - 0.0004 20.2 3.3 0.38 10.8 0.0 5.7 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 EMC95779.1 - 0.00053 20.4 3.6 1.6 9.3 0.1 5.5 5 0 0 5 5 5 1 PQQ-like domain Kelch_6 PF13964.6 EMC95779.1 - 0.00094 19.4 2.9 0.031 14.6 0.5 3.1 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 EMC95779.1 - 0.049 13.6 2.3 0.1 12.6 0.5 2.6 2 0 0 2 2 2 0 Kelch motif IKI3 PF04762.12 EMC95779.1 - 0.078 11.0 0.1 0.99 7.3 0.0 2.4 3 0 0 3 3 3 0 IKI3 family DPPIV_N PF00930.21 EMC95779.1 - 0.11 11.2 0.8 1.9 7.2 0.1 3.0 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40_like PF17005.5 EMC95779.1 - 0.17 11.2 0.0 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 EMC95779.1 - 0.94 8.4 7.1 40 3.0 0.1 5.4 5 1 2 7 7 7 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AP_endonuc_2 PF01261.24 EMC95780.1 - 5.1e-33 114.3 0.7 8.2e-33 113.6 0.7 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel JmjC PF02373.22 EMC95781.1 - 6e-10 39.5 0.1 1.3e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EMC95781.1 - 4.6e-08 32.8 7.8 4.6e-08 32.8 7.8 2.4 2 0 0 2 2 2 1 PHD-finger Cupin_8 PF13621.6 EMC95781.1 - 5e-07 29.7 0.1 2.5e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 Cupin-like domain JHD PF17811.1 EMC95781.1 - 4.6e-06 27.1 0.4 9.6e-06 26.1 0.4 1.5 1 0 0 1 1 1 1 Jumonji helical domain PHD_2 PF13831.6 EMC95781.1 - 0.011 15.3 3.4 0.011 15.3 3.4 3.0 4 0 0 4 4 4 0 PHD-finger Zn_clus PF00172.18 EMC95781.1 - 3.3 7.9 29.3 0.33 11.1 6.8 3.7 3 1 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD_Oberon PF07227.11 EMC95781.1 - 3.4 7.6 9.2 0.28 11.1 3.8 1.9 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein zf-piccolo PF05715.13 EMC95781.1 - 7.5 6.8 8.4 2 8.6 4.5 2.1 2 0 0 2 2 2 0 Piccolo Zn-finger zf-CW PF07496.15 EMC95781.1 - 8.6 6.5 15.0 0.25 11.4 3.0 3.1 3 0 0 3 3 3 0 CW-type Zinc Finger RRM_1 PF00076.22 EMC95782.1 - 1.4e-13 50.4 0.4 1.6e-12 47.0 0.1 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMC95782.1 - 8e-06 25.5 0.0 9.6e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC95782.1 - 0.036 13.9 0.0 0.058 13.3 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif DPCD PF14913.6 EMC95782.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 DPCD protein family Carboxyl_trans PF01039.22 EMC95783.1 - 4.1e-77 259.9 0.0 5.3e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain zf-CCCH_4 PF18044.1 EMC95784.1 - 2.5e-13 49.5 9.9 4.9e-07 29.4 3.3 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 EMC95784.1 - 5.2e-11 42.2 9.3 1.9e-06 27.6 1.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EMC95784.1 - 3.6e-08 34.1 8.1 0.00095 19.8 1.2 2.2 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 EMC95784.1 - 5.8e-08 32.5 18.5 2e-06 27.6 2.5 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 EMC95784.1 - 4.4e-05 23.8 14.3 0.0013 19.2 2.0 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EMC95784.1 - 0.0012 19.0 1.1 0.0017 18.5 1.1 1.2 1 0 0 1 1 1 1 Zinc-finger containing family zf_CCCH_5 PF18384.1 EMC95784.1 - 2.9 8.1 7.5 2.4 8.3 1.4 2.4 2 0 0 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) DUF2048 PF09752.9 EMC95788.1 - 0.03 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 ADH_zinc_N PF00107.26 EMC95790.1 - 9.6e-22 77.4 0.0 2e-21 76.3 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC95790.1 - 1.1e-19 71.9 0.0 1.7e-19 71.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC95790.1 - 2e-10 40.5 0.0 1e-07 31.8 0.0 3.0 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Peptidase_C2 PF00648.21 EMC95792.1 - 2.3e-64 217.3 2.0 4.7e-43 147.3 0.2 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Yippee-Mis18 PF03226.14 EMC95795.1 - 3.2e-23 81.9 0.0 4.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EMC95795.1 - 0.0095 16.2 0.1 0.03 14.6 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of RIG-I zf-ribbon_3 PF13248.6 EMC95795.1 - 0.018 14.4 0.1 0.039 13.4 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EMC95795.1 - 0.1 12.2 0.1 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding SnAC PF14619.6 EMC95795.1 - 0.15 12.6 2.6 0.16 12.6 1.2 1.8 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex DUF678 PF05077.12 EMC95795.1 - 4.8 7.4 5.7 24 5.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF678) PDZ_1 PF12812.7 EMC95798.1 - 2.4e-48 162.0 0.0 3.8e-31 106.9 0.0 3.0 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EMC95798.1 - 9.6e-26 91.5 0.6 1.9e-20 74.3 0.0 3.1 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 EMC95798.1 - 1.5e-16 59.9 0.1 1.5e-08 34.4 0.2 3.8 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 EMC95798.1 - 1.4e-14 54.1 1.9 8.1e-07 29.3 0.1 4.0 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 EMC95798.1 - 5.3e-11 42.7 0.0 1.3e-05 25.4 0.0 3.1 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 EMC95798.1 - 0.00071 19.4 0.0 0.0031 17.4 0.0 2.0 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 EMC95798.1 - 0.00086 19.2 0.5 0.3 11.1 0.2 2.8 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 EMC95798.1 - 0.1 11.3 0.0 0.22 10.1 0.0 1.5 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.16 EMC95798.1 - 0.23 10.9 0.2 0.37 10.3 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) GMC_oxred_N PF00732.19 EMC95799.1 - 1.9e-48 165.3 0.0 2.4e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EMC95799.1 - 0.0011 18.2 0.1 0.18 11.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC95799.1 - 0.0017 17.7 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMC95799.1 - 0.0018 17.4 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMC95799.1 - 0.012 15.8 0.1 0.043 14.1 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMC95799.1 - 0.019 14.0 0.4 1.6 7.7 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EMC95799.1 - 0.085 12.4 3.3 0.42 10.1 2.5 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMC95799.1 - 0.13 12.2 0.6 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EMC95799.1 - 0.24 10.4 0.2 14 4.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NIF3 PF01784.18 EMC95800.1 - 6.7e-61 206.0 0.0 9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 EMC95801.1 - 3.2e-15 56.2 0.0 3.5e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein Pyr_redox_2 PF07992.14 EMC95802.1 - 2.8e-39 135.1 0.0 9.6e-35 120.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC95802.1 - 2.7e-09 37.5 0.0 1.9e-06 28.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EMC95802.1 - 0.21 11.7 0.0 0.56 10.3 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_cc PF11790.8 EMC95804.1 - 1.1e-52 179.0 4.4 1.3e-52 178.8 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Cellulase PF00150.18 EMC95804.1 - 0.013 14.9 0.3 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) PHO4 PF01384.20 EMC95806.1 - 1.2e-97 327.0 18.8 1.5e-97 326.7 18.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family EpsG PF14897.6 EMC95806.1 - 1.7 7.9 7.4 3.7 6.8 7.4 1.5 1 0 0 1 1 1 0 EpsG family UPF0444 PF15475.6 EMC95806.1 - 2.3 8.5 9.0 1.4 9.2 0.5 2.7 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Kelch_4 PF13418.6 EMC95808.1 - 3.2e-18 65.5 2.0 9.4e-07 28.8 0.1 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EMC95808.1 - 1.1e-15 57.4 7.0 7.2e-05 23.0 0.0 5.5 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EMC95808.1 - 3.2e-11 42.6 0.2 0.011 15.3 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 EMC95808.1 - 7e-11 41.9 8.0 0.029 14.3 0.0 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EMC95808.1 - 3.1e-09 36.4 0.7 0.059 13.4 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 EMC95808.1 - 1.1e-07 31.9 2.1 0.068 13.5 0.0 4.7 5 0 0 5 5 5 3 Kelch motif His_biosynth PF00977.21 EMC95809.1 - 4.6e-48 163.7 0.1 3e-47 161.0 0.2 2.3 2 1 0 2 2 2 1 Histidine biosynthesis protein GATase PF00117.28 EMC95809.1 - 1.8e-20 73.5 0.0 3.1e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EMC95809.1 - 1.8e-08 34.4 0.0 7.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EMC95809.1 - 5.3e-05 22.9 0.0 0.00019 21.1 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EMC95809.1 - 0.017 14.9 0.0 0.05 13.3 0.0 1.8 1 1 0 1 1 1 0 Peptidase C26 Dus PF01207.17 EMC95809.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EMC95809.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase SOR_SNZ PF01680.17 EMC95809.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 SOR/SNZ family SAP PF02037.27 EMC95809.1 - 0.18 11.6 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 SAP domain S4 PF01479.25 EMC95810.1 - 5.3e-13 48.5 0.0 9.4e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EMC95810.1 - 1.1e-07 32.7 0.0 1.7e-07 32.1 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Glucodextran_N PF09137.11 EMC95811.1 - 0.053 13.1 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 Glucodextranase, domain N K_trans PF02705.16 EMC95812.1 - 1.7e-178 594.5 14.2 2.1e-178 594.2 14.2 1.0 1 0 0 1 1 1 1 K+ potassium transporter IMS PF00817.20 EMC95815.1 - 2.9e-38 131.2 0.0 6.6e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EMC95815.1 - 1.6e-26 92.5 4.7 3.5e-26 91.4 4.7 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 EMC95815.1 - 1.2e-17 62.6 22.0 3.3e-10 39.1 4.1 4.2 4 0 0 4 4 4 3 Ubiquitin binding region IMS_C PF11799.8 EMC95815.1 - 7.3e-15 55.7 0.0 1.7e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EMC95815.1 - 4.8e-11 42.9 0.0 4e-10 40.0 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EMC95815.1 - 1.4e-05 25.3 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 EMC95815.1 - 0.0013 19.1 0.0 0.0033 17.7 0.0 1.7 1 0 0 1 1 1 1 minimal CRISPR polymerase domain PTCB-BRCT PF12738.7 EMC95815.1 - 0.0019 18.1 0.0 0.0052 16.7 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EMC95815.1 - 0.0033 17.8 0.0 0.009 16.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 EMC95815.1 - 0.048 14.0 2.4 0.11 12.9 0.1 3.0 3 0 0 3 3 2 0 IMS family HHH motif EnY2 PF10163.9 EMC95815.1 - 0.12 12.8 0.6 16 5.9 0.0 3.8 4 0 0 4 4 4 0 Transcription factor e(y)2 RCC_reductase PF06405.11 EMC95815.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) MgtE_N PF03448.17 EMC95815.1 - 0.14 12.8 0.9 1.2e+02 3.4 0.0 3.8 3 0 0 3 3 3 0 MgtE intracellular N domain Ada_Zn_binding PF02805.16 EMC95816.1 - 1.4e-32 111.5 4.3 1.9e-32 111.1 4.3 1.2 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EMC95816.1 - 3.1e-08 33.5 0.0 6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EMC95816.1 - 6e-06 26.4 0.5 1e-05 25.7 0.2 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain Flavin_Reduct PF01613.18 EMC95817.1 - 2.1e-13 50.6 0.0 3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EMC95817.1 - 8.5e-07 28.9 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF447) H2O2_YaaD PF03883.14 EMC95817.1 - 0.17 11.4 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Peroxide stress protein YaaA PP2C PF00481.21 EMC95818.1 - 1.7e-51 175.3 0.0 3.2e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EMC95818.1 - 1.8e-39 133.3 60.3 1.2e-08 34.6 4.2 11.6 5 3 6 13 13 13 11 Leucine rich repeat LRR_4 PF12799.7 EMC95818.1 - 5.6e-37 125.1 65.0 4.5e-05 23.7 1.3 13.4 9 3 2 13 13 13 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EMC95818.1 - 9.7e-29 100.3 0.0 3.6e-28 98.4 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 EMC95818.1 - 3.4e-09 36.0 46.2 1.3 9.9 0.1 15.4 17 1 0 17 17 17 3 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.11 EMC95818.1 - 5.5e-08 32.4 0.1 1.4e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.23 EMC95818.1 - 7.1e-05 23.4 0.1 0.00027 21.5 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.6 EMC95818.1 - 0.00018 21.1 22.0 0.01 15.3 3.4 5.6 2 1 5 7 7 7 5 Leucine-rich repeat LRR_6 PF13516.6 EMC95818.1 - 3.7 7.8 53.0 2.9 8.2 0.2 13.3 15 0 0 15 15 15 0 Leucine Rich repeat MscS_TM PF12794.7 EMC95819.1 - 0.15 10.9 1.1 0.26 10.1 0.8 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 MOSC PF03473.17 EMC95820.1 - 3.2e-36 124.2 0.0 5e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EMC95820.1 - 1.3e-14 54.1 0.0 2.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2399 PF09664.10 EMC95820.1 - 0.024 14.6 0.1 0.054 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) Toprim_2 PF13155.6 EMC95820.1 - 0.1 13.1 0.0 0.5 10.8 0.0 2.0 2 0 0 2 2 2 0 Toprim-like Fungal_trans_2 PF11951.8 EMC95822.1 - 0.00018 20.5 0.1 0.00024 20.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EFhand_Ca_insen PF08726.10 EMC95822.1 - 0.0065 16.5 0.0 0.075 13.1 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Clat_adaptor_s PF01217.20 EMC95823.1 - 1.8e-56 190.1 0.7 2e-56 189.8 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Zn_clus PF00172.18 EMC95825.1 - 5.2e-08 32.9 14.9 1.1e-07 31.9 14.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 EMC95826.1 - 1.2e-06 29.3 0.1 1.8e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC95826.1 - 0.00013 21.3 0.1 0.00025 20.4 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMC95826.1 - 0.00058 19.6 0.0 0.0014 18.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC95826.1 - 0.016 14.7 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 EMC95826.1 - 0.042 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ammonium_transp PF00909.21 EMC95828.1 - 8.5e-117 390.2 32.3 9.7e-117 390.0 32.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Acetyltransf_1 PF00583.25 EMC95829.1 - 2.5e-15 56.7 0.0 3.2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMC95829.1 - 4.1e-09 36.3 0.0 6.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EMC95829.1 - 7.9e-09 35.5 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC95829.1 - 2.4e-07 31.1 0.0 3.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMC95829.1 - 9e-07 29.6 0.0 1.1e-06 29.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMC95829.1 - 5.8e-05 22.8 0.0 7.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC95829.1 - 7.1e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMC95829.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EMC95829.1 - 0.042 14.0 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EMC95829.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase LCAT PF02450.15 EMC95830.1 - 8.8e-99 331.3 0.0 1.1e-98 331.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EMC95830.1 - 0.0015 19.1 1.2 0.25 11.9 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family CPSase_L_D2 PF02786.17 EMC95831.1 - 6e-53 179.5 0.0 9.1e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EMC95831.1 - 8.2e-34 116.0 0.0 4.6e-33 113.5 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EMC95831.1 - 3.3e-30 104.9 0.1 1.1e-29 103.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EMC95831.1 - 5.3e-12 45.4 1.8 1.3e-11 44.1 1.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EMC95831.1 - 6.4e-06 25.8 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DUF2118 PF09891.9 EMC95831.1 - 0.0024 17.8 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_3 PF02655.14 EMC95831.1 - 0.047 13.7 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EMC95831.1 - 0.071 13.0 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like DUF5017 PF16409.5 EMC95831.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5017) EF-hand_13 PF17958.1 EMC95831.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Polysacc_deac_1 PF01522.21 EMC95832.1 - 1.8e-16 60.2 0.0 2.8e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMC95832.1 - 0.0011 18.7 0.5 0.0059 16.3 0.4 2.3 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 EMC95832.1 - 0.032 12.6 0.0 0.044 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) APG9 PF04109.16 EMC95833.1 - 7.3e-179 595.8 10.7 8.5e-179 595.5 10.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF829 PF05705.14 EMC95834.1 - 3.1e-11 43.6 0.0 4.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Kinesin PF00225.23 EMC95835.1 - 2.5e-85 286.3 1.7 3.7e-85 285.8 1.7 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMC95835.1 - 2.6e-23 82.6 0.0 5.1e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 EMC95835.1 - 0.00033 20.4 0.2 0.065 13.1 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 EMC95835.1 - 0.00073 19.7 0.0 0.0023 18.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EMC95835.1 - 0.0067 17.0 0.8 0.041 14.5 0.8 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain KIAA1430 PF13879.6 EMC95835.1 - 6.5 7.6 9.0 1 10.2 0.3 3.2 2 1 0 2 2 2 0 KIAA1430 homologue Cation_efflux PF01545.21 EMC95836.1 - 1.4e-43 149.0 2.5 1.4e-43 149.0 2.5 2.2 2 0 0 2 2 2 1 Cation efflux family Zip PF02535.22 EMC95836.1 - 0.0021 17.3 24.8 0.0021 17.3 24.8 2.8 1 1 2 3 3 3 1 ZIP Zinc transporter SPX PF03105.19 EMC95836.1 - 0.15 11.9 2.0 0.29 11.0 2.0 1.4 1 1 0 1 1 1 0 SPX domain Glyco_trans_1_4 PF13692.6 EMC95837.1 - 1.7e-06 28.5 0.0 4.9e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EMC95837.1 - 2.8e-05 23.7 0.0 5.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMC95837.1 - 0.00031 21.2 0.1 0.0007 20.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EMC95837.1 - 0.0082 16.2 0.3 0.019 15.0 0.3 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 SHNi-TPR PF10516.9 EMC95838.1 - 6.8e-14 51.0 0.8 6.8e-14 51.0 0.8 2.4 2 0 0 2 2 2 1 SHNi-TPR Aerolysin PF01117.20 EMC95838.1 - 0.061 12.5 0.5 0.52 9.5 0.2 2.2 2 0 0 2 2 2 0 Aerolysin toxin TPR_12 PF13424.6 EMC95838.1 - 0.086 13.1 3.7 3.5 8.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CCDC-167 PF15188.6 EMC95838.1 - 0.21 12.0 2.3 0.59 10.5 2.0 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 AAA_13 PF13166.6 EMC95838.1 - 0.78 8.3 17.8 0.97 8.0 8.5 2.3 2 0 0 2 2 2 0 AAA domain AA_permease_2 PF13520.6 EMC95839.1 - 9.4e-11 41.2 13.1 1e-10 41.0 13.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF883 PF05957.13 EMC95840.1 - 0.0038 17.8 16.4 0.029 15.0 1.7 2.6 1 1 0 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 EMC95840.1 - 0.011 15.6 16.7 0.082 12.8 16.7 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EMC95840.1 - 0.014 15.9 25.4 1.4e+03 -0.1 0.0 4.0 2 2 0 2 2 2 0 YtxH-like protein ApoLp-III PF07464.11 EMC95840.1 - 0.038 14.1 15.1 0.023 14.8 13.2 1.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PET10 PF17316.2 EMC95840.1 - 0.056 13.0 0.0 0.056 13.0 0.0 3.3 2 2 1 3 3 3 0 Petite colonies protein 10 Mucin-like PF16058.5 EMC95840.1 - 0.075 13.1 5.7 0.14 12.2 5.7 1.5 1 0 0 1 1 1 0 Mucin-like ATP-synt_B PF00430.18 EMC95840.1 - 0.9 9.6 24.1 1.1 9.3 13.3 2.4 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) ZYG-11_interact PF05884.12 EMC95840.1 - 3.3 7.0 9.7 24 4.2 0.0 2.7 2 1 1 3 3 3 0 Interactor of ZYG-11 Neur_chan_memb PF02932.16 EMC95840.1 - 9.2 6.2 8.2 16 5.5 8.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BTK PF00779.19 EMC95841.1 - 0.013 15.3 1.2 0.019 14.8 1.2 1.3 1 0 0 1 1 1 0 BTK motif MOZ_SAS PF01853.18 EMC95843.1 - 1.5e-66 223.5 0.0 2e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EMC95843.1 - 2.5e-14 52.6 3.3 4.7e-14 51.7 3.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EMC95843.1 - 0.0087 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC95843.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HET PF06985.11 EMC95844.1 - 0.0015 18.9 4.4 0.0015 18.9 4.4 2.4 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Clat_adaptor_s PF01217.20 EMC95846.1 - 2.9e-14 53.2 1.7 3e-13 49.9 1.7 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain HATPase_c_2 PF13581.6 EMC95847.1 - 0.18 11.7 0.8 0.58 10.1 0.1 2.1 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain MFS_1 PF07690.16 EMC95848.1 - 1.9e-37 129.0 23.7 1.9e-37 129.0 23.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMC95848.1 - 0.00078 18.4 3.0 0.00078 18.4 3.0 1.8 1 1 1 2 2 2 1 MFS_1 like family Abhydrolase_9_N PF15420.6 EMC95848.1 - 0.017 15.1 0.0 0.017 15.1 0.0 2.6 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Bax1-I PF01027.20 EMC95848.1 - 2 8.2 17.0 0.9 9.3 2.5 3.0 2 2 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Allantoicase PF03561.15 EMC95849.1 - 1.4e-92 307.2 0.0 1.8e-47 160.9 0.0 2.4 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 EMC95849.1 - 1.6e-30 105.5 0.7 3.3e-30 104.4 0.7 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 EMC95849.1 - 1.4e-19 70.5 0.0 1.2e-13 51.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMC95849.1 - 7.7e-11 42.0 0.1 8.9e-10 38.6 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EMC95849.1 - 7e-10 38.9 0.1 7.3e-05 23.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EMC95849.1 - 1e-09 38.7 0.6 2.5e-06 27.9 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC95849.1 - 5e-07 29.5 0.0 0.013 16.0 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat HATPase_c PF02518.26 EMC95850.1 - 2.1e-33 115.2 0.0 5e-33 114.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMC95850.1 - 2.2e-21 76.1 0.0 6.6e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EMC95850.1 - 1.8e-19 69.5 2.8 5.5e-19 68.0 0.1 3.0 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EMC95850.1 - 5.7e-16 59.4 0.1 6.7e-15 55.9 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 EMC95850.1 - 3.6e-10 40.3 0.0 8.5e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EMC95850.1 - 1.3e-09 38.7 0.0 4e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 EMC95850.1 - 1.6e-09 37.6 0.0 3.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain NACHT PF05729.12 EMC95850.1 - 7.2e-05 22.8 0.0 0.4 10.6 0.0 3.3 3 0 0 3 3 3 2 NACHT domain HATPase_c_3 PF13589.6 EMC95850.1 - 0.00054 19.8 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 EMC95850.1 - 0.0012 19.2 0.0 0.005 17.2 0.0 2.2 2 0 0 2 2 2 1 GAF domain RsgA_GTPase PF03193.16 EMC95850.1 - 0.0097 15.8 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 EMC95850.1 - 0.0097 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_35 PF14516.6 EMC95850.1 - 0.023 13.6 0.0 0.084 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.6 EMC95850.1 - 0.037 14.3 0.1 0.36 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Glyco_trans_4_3 PF12000.8 EMC95850.1 - 0.072 12.8 0.0 0.24 11.1 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 4 group DUF815 PF05673.13 EMC95850.1 - 0.13 11.4 0.5 0.75 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) LCM PF04072.14 EMC95851.1 - 4.8e-28 98.4 0.0 9.4e-28 97.4 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase UQ_con PF00179.26 EMC95851.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme HlyD_D4 PF16572.5 EMC95851.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB RNA_pol_Rpb5_N PF03871.14 EMC95852.1 - 2.7e-27 95.2 0.0 3.6e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 EMC95852.1 - 0.023 14.5 0.1 0.054 13.4 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain AIRC PF00731.20 EMC95853.1 - 6.3e-56 188.1 1.6 1.2e-55 187.2 1.6 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EMC95853.1 - 1.3e-49 168.0 0.0 2e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EMC95853.1 - 1.5e-15 56.6 0.1 3.8e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EMC95853.1 - 0.00013 21.6 0.0 0.00054 19.6 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EMC95853.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain AlaDh_PNT_C PF01262.21 EMC95853.1 - 0.0024 17.2 0.1 0.0051 16.1 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EMC95853.1 - 0.025 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.17 EMC95853.1 - 0.029 13.9 0.3 0.09 12.3 0.0 2.0 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, ATP binding domain 3HCDH_N PF02737.18 EMC95853.1 - 0.11 12.4 0.2 0.32 10.9 0.1 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Radical_SAM PF04055.21 EMC95853.1 - 0.14 12.6 0.1 0.71 10.2 0.0 2.1 2 1 1 3 3 3 0 Radical SAM superfamily PrpR_N PF06506.11 EMC95853.1 - 0.2 11.2 0.7 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Propionate catabolism activator XPG_N PF00752.17 EMC95857.1 - 1.5e-29 102.4 0.0 1.5e-29 102.4 0.0 2.2 2 1 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EMC95857.1 - 1.5e-29 102.2 1.9 6e-29 100.2 0.0 2.5 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EMC95857.1 - 2.1e-05 25.0 0.9 9.5e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EMC95857.1 - 0.012 16.2 0.0 0.034 14.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Fe_dep_repr_C PF02742.15 EMC95857.1 - 0.055 13.6 0.2 13 6.0 0.0 3.2 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain HXXSHH PF07586.11 EMC95857.1 - 8.9 5.8 7.6 5.8 6.4 5.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Acyl-CoA_dh_N PF02771.16 EMC95858.1 - 9e-24 84.3 0.1 1.6e-23 83.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EMC95858.1 - 1.7e-21 77.0 0.2 2.8e-21 76.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMC95858.1 - 1.7e-16 60.2 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMC95858.1 - 0.00083 19.6 0.6 0.00083 19.6 0.6 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Aminotran_1_2 PF00155.21 EMC95859.1 - 0.003 16.8 0.5 0.0056 15.9 0.5 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II ERM PF00769.19 EMC95859.1 - 0.78 9.5 31.0 0.012 15.4 22.1 2.3 3 0 0 3 3 3 0 Ezrin/radixin/moesin family FUSC PF04632.12 EMC95859.1 - 1.6 7.2 11.7 3 6.2 11.7 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family TFIIIC_sub6 PF10419.9 EMC95860.1 - 2.6e-13 49.6 0.0 5.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Vps62 PF06101.11 EMC95861.1 - 1.4e-10 40.1 1.6 1.2e-09 37.1 0.1 2.4 3 0 0 3 3 3 2 Vacuolar protein sorting-associated protein 62 Exo_endo_phos PF03372.23 EMC95862.1 - 2.8e-11 43.4 0.0 4.9e-11 42.6 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lectin_leg-like PF03388.13 EMC95865.1 - 5.6e-31 107.7 0.1 8.2e-31 107.1 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family ABC_tran_CTD PF16326.5 EMC95865.1 - 0.022 15.0 0.3 8.8 6.7 0.0 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain GrpE PF01025.19 EMC95865.1 - 0.036 13.7 1.2 0.22 11.2 1.2 1.9 1 1 0 1 1 1 0 GrpE PRTP PF01366.18 EMC95865.1 - 0.05 11.7 0.2 0.068 11.2 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein PspA_IM30 PF04012.12 EMC95865.1 - 0.074 12.6 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 PspA/IM30 family Baculo_PEP_C PF04513.12 EMC95865.1 - 0.085 12.9 0.7 0.22 11.6 0.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALIX_LYPXL_bnd PF13949.6 EMC95865.1 - 0.087 12.1 0.9 0.12 11.7 0.9 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV BAR PF03114.18 EMC95865.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 BAR domain DUF1664 PF07889.12 EMC95865.1 - 0.11 12.5 0.3 0.25 11.4 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CCDC154 PF15450.6 EMC95865.1 - 0.14 10.7 0.8 0.2 10.1 0.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 ApoLp-III PF07464.11 EMC95865.1 - 0.17 12.0 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3483 PF11982.8 EMC95865.1 - 0.17 11.5 0.2 0.29 10.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) TBCC_N PF16752.5 EMC95865.1 - 0.18 12.2 0.4 0.47 10.9 0.2 1.7 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Band_7 PF01145.25 EMC95866.1 - 2.9e-23 82.8 4.6 2.9e-23 82.8 4.6 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family Indigoidine_A PF04227.12 EMC95867.1 - 9.5e-119 396.1 0.5 1.3e-118 395.6 0.5 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EMC95867.1 - 1.7e-19 70.3 0.3 4e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.14 EMC95868.1 - 1.1e-117 394.0 0.6 1.2e-117 393.8 0.6 1.0 1 0 0 1 1 1 1 Ribophorin I DRIM PF07539.12 EMC95869.1 - 5.6e-154 513.8 1.0 5.6e-154 513.8 1.0 4.2 6 0 0 6 6 6 1 Down-regulated in metastasis V-ATPase_H_C PF11698.8 EMC95869.1 - 0.038 14.1 0.6 24 5.1 0.0 4.7 4 0 0 4 4 4 0 V-ATPase subunit H Symplekin_C PF12295.8 EMC95869.1 - 0.055 13.6 3.8 10 6.2 0.3 4.1 2 1 1 3 3 3 0 Symplekin tight junction protein C terminal RIG-I_C PF18119.1 EMC95869.1 - 0.13 12.2 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain UME PF08064.13 EMC95869.1 - 0.44 10.5 6.8 13 5.7 0.0 5.0 5 0 0 5 5 5 0 UME (NUC010) domain CwfJ_C_1 PF04677.15 EMC95870.1 - 4.6e-23 81.4 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EMC95870.1 - 6e-16 59.1 2.1 1.3e-15 58.0 2.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Cullin PF00888.22 EMC95871.1 - 1.4e-192 641.6 1.2 1.8e-192 641.3 1.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EMC95871.1 - 2.4e-26 91.5 0.6 6.9e-26 90.1 0.6 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.10 EMC95871.1 - 0.053 13.3 0.4 1.2 9.0 0.2 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain zf-DNL PF05180.12 EMC95872.1 - 1.5e-28 98.5 1.0 1.9e-28 98.2 1.0 1.1 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.18 EMC95872.1 - 0.026 14.4 1.1 4 7.4 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 EMC95872.1 - 0.028 14.4 0.6 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.13 EMC95872.1 - 0.056 13.5 1.0 0.093 12.8 0.9 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 EMC95872.1 - 0.073 13.1 4.8 2.8 8.0 0.7 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.19 EMC95872.1 - 0.12 12.4 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RasGEF PF00617.19 EMC95873.1 - 2.5e-48 164.6 0.0 3.2e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain IBR PF01485.21 EMC95874.1 - 9.4e-21 73.8 53.1 9.1e-12 45.0 9.7 4.7 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EMC95874.1 - 0.0002 21.1 4.1 0.0002 21.1 4.1 5.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC95874.1 - 0.0032 17.5 4.7 0.0032 17.5 4.7 3.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EMC95874.1 - 0.0033 17.7 6.6 0.0033 17.7 6.6 4.1 3 1 1 4 4 4 1 Ring finger domain UN_NPL4 PF11543.8 EMC95874.1 - 0.02 15.4 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mo25 PF08569.11 EMC95877.1 - 4.3e-120 401.0 0.0 4.9e-120 400.8 0.0 1.0 1 0 0 1 1 1 1 Mo25-like HopW1-1 PF15457.6 EMC95877.1 - 0.13 11.5 0.1 0.55 9.4 0.0 1.8 2 0 0 2 2 2 0 Type III T3SS secreted effector HopW1-1/HopPmaA Med30 PF11315.8 EMC95877.1 - 0.14 12.4 0.8 0.22 11.7 0.2 1.7 2 0 0 2 2 2 0 Mediator complex subunit 30 Sun2_CC2 PF18580.1 EMC95877.1 - 0.21 11.8 0.8 1 9.6 0.3 2.3 1 1 1 2 2 2 0 SUN2 coiled coil domain 2 MFS_1 PF07690.16 EMC95878.1 - 2.9e-32 112.0 28.5 2.9e-32 112.0 28.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.20 EMC95879.1 - 3.3e-12 46.8 0.0 6.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMC95879.1 - 3e-08 34.4 0.0 6.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WW PF00397.26 EMC95882.1 - 2.3e-05 24.4 3.5 2.3e-05 24.4 3.5 2.0 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 EMC95882.1 - 0.0015 18.6 4.6 0.0023 18.1 4.5 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Glyco_trans_2_3 PF13632.6 EMC95883.1 - 7.2e-24 84.8 0.8 7.2e-24 84.8 0.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMC95883.1 - 8.1e-07 29.1 0.0 2.7e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF2417 PF10329.9 EMC95883.1 - 0.0011 18.4 0.4 0.0011 18.4 0.4 1.6 2 0 0 2 2 2 1 Region of unknown function (DUF2417) UIM PF02809.20 EMC95884.1 - 0.032 14.2 0.1 0.11 12.5 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif F-box-like PF12937.7 EMC95885.1 - 0.00068 19.5 0.1 0.0054 16.6 0.0 2.5 2 0 0 2 2 2 1 F-box-like NIF PF03031.18 EMC95886.1 - 8.1e-25 87.4 0.0 2.4e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EMC95886.1 - 1.2e-06 28.8 0.0 2.7e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EMC95886.1 - 0.00031 20.6 0.0 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EMC95886.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT_2 PF16589.5 EMC95886.1 - 0.022 15.2 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Glyco_hydro_20 PF00728.22 EMC95886.1 - 0.046 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Sec23_trunk PF04811.15 EMC95887.1 - 1.2e-68 231.3 0.0 1.8e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EMC95887.1 - 3.6e-24 84.5 0.0 1.9e-23 82.3 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EMC95887.1 - 1.6e-17 64.0 0.0 4.6e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EMC95887.1 - 6.4e-16 58.1 5.0 1.2e-15 57.3 5.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EMC95887.1 - 5.9e-08 32.5 0.0 1.5e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EMC95887.1 - 0.012 15.0 0.3 0.025 14.0 0.3 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MFS_1 PF07690.16 EMC95888.1 - 6.6e-40 137.1 62.8 5.8e-37 127.4 43.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 EMC95888.1 - 0.00019 20.3 0.4 0.00019 20.3 0.4 2.3 2 1 0 2 2 2 1 LacY proton/sugar symporter AA_permease_2 PF13520.6 EMC95889.1 - 2.6e-60 204.4 47.1 3.2e-60 204.2 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC95889.1 - 3.5e-18 65.5 39.0 5e-18 64.9 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease Renin_r PF07850.14 EMC95889.1 - 1.4 9.6 3.1 0.85 10.3 0.1 2.2 2 0 0 2 2 2 0 Renin receptor-like protein Peptidase_C70 PF12385.8 EMC95890.1 - 0.05 13.6 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Glyco_transf_20 PF00982.21 EMC95891.1 - 6.4e-198 658.2 0.0 7.4e-198 658.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 EMC95891.1 - 0.0001 22.7 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EMC95891.1 - 0.0019 18.0 0.1 0.006 16.3 0.0 1.8 3 0 0 3 3 3 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EMC95891.1 - 0.03 13.9 0.2 0.26 10.8 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 DUF4897 PF16238.5 EMC95891.1 - 0.047 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) NPIP PF06409.11 EMC95893.1 - 1.1 8.3 4.2 2.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Nuclear pore complex interacting protein (NPIP) RTA1 PF04479.13 EMC95894.1 - 0.00032 20.4 2.6 0.00032 20.4 2.6 1.6 1 1 1 2 2 2 1 RTA1 like protein DUF3397 PF11877.8 EMC95894.1 - 0.23 11.7 10.2 0.31 11.3 0.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3397) Glyco_transf_8 PF01501.20 EMC95895.1 - 0.008 15.8 1.2 0.32 10.5 1.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EMC95895.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative DnaJ PF00226.31 EMC95896.1 - 1.6e-25 89.0 3.5 2.6e-25 88.3 3.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EMC95896.1 - 4.4e-25 88.5 0.0 5.9e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EMC95896.1 - 1.8e-13 50.7 19.2 3e-13 49.9 19.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EMC95896.1 - 0.011 15.7 13.0 0.13 12.3 2.9 2.6 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 EMC95896.1 - 0.091 12.4 7.9 1.5 8.4 0.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 EMC95896.1 - 0.13 12.3 12.9 0.46 10.5 3.2 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rad21_Rec8_N PF04825.13 EMC95897.1 - 5.9e-33 113.3 0.1 9.9e-33 112.6 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EMC95897.1 - 7.5e-07 28.3 0.1 1.8e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1-E2_ATPase PF00122.20 EMC95899.1 - 1e-44 152.2 2.7 1.2e-44 152.0 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMC95899.1 - 1.1e-36 126.3 0.1 2.9e-36 124.9 0.1 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMC95899.1 - 7.7e-24 85.1 1.2 6.5e-23 82.1 1.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMC95899.1 - 4.3e-17 61.6 0.1 7.5e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EMC95899.1 - 3.9e-15 55.7 0.0 7.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMC95899.1 - 2e-05 24.5 0.2 0.00097 19.0 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_A24 PF01478.18 EMC95899.1 - 0.0083 16.5 0.0 2.4 8.6 0.7 2.9 2 1 0 2 2 2 1 Type IV leader peptidase family HAD PF12710.7 EMC95899.1 - 0.071 13.5 0.2 0.2 12.0 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PUB_1 PF18486.1 EMC95899.1 - 0.25 11.2 1.0 0.84 9.5 0.1 2.2 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Cupin_1 PF00190.22 EMC95901.1 - 1.3e-15 57.3 0.2 1.6e-15 57.0 0.2 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EMC95901.1 - 6.2e-05 22.6 0.0 8.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain ATP_bind_1 PF03029.17 EMC95902.1 - 7.1e-77 258.4 0.1 9.8e-77 258.0 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 EMC95902.1 - 3.6e-05 23.8 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EMC95902.1 - 6.4e-05 22.8 0.0 0.00018 21.3 0.0 1.7 2 0 0 2 2 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 EMC95902.1 - 0.00047 20.7 0.0 0.003 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EMC95902.1 - 0.00089 19.0 0.0 0.0023 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMC95902.1 - 0.0013 19.2 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EMC95902.1 - 0.0014 19.1 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EMC95902.1 - 0.0033 16.5 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EMC95902.1 - 0.0035 17.6 0.1 0.0082 16.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 EMC95902.1 - 0.004 17.5 0.0 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase GTP_EFTU PF00009.27 EMC95902.1 - 0.0049 16.4 0.1 2.3 7.7 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 EMC95902.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 EMC95902.1 - 0.0086 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EMC95902.1 - 0.0089 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NACHT PF05729.12 EMC95902.1 - 0.0091 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 EMC95902.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EMC95902.1 - 0.016 14.8 0.1 0.44 10.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 EMC95902.1 - 0.02 15.0 0.0 0.036 14.1 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 EMC95902.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 EMC95902.1 - 0.024 14.5 0.1 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 EMC95902.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EMC95902.1 - 0.029 14.4 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EMC95902.1 - 0.031 14.8 0.0 0.062 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 EMC95902.1 - 0.045 13.0 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_19 PF13245.6 EMC95902.1 - 0.048 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EMC95902.1 - 0.049 13.4 0.1 0.19 11.5 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Thymidylate_kin PF02223.17 EMC95902.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_31 PF13614.6 EMC95902.1 - 0.068 13.1 0.0 3.3 7.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EMC95902.1 - 0.075 13.1 0.0 0.36 10.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EMC95902.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 EMC95902.1 - 0.1 12.0 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF463 PF04317.12 EMC95902.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 ATPase PF06745.13 EMC95902.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiC MeaB PF03308.16 EMC95902.1 - 0.14 11.1 0.0 0.38 9.7 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 EMC95902.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.2 1 1 0 1 1 1 0 KAP family P-loop domain RsgA_GTPase PF03193.16 EMC95902.1 - 0.18 11.7 0.1 0.74 9.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase His_Phos_1 PF00300.22 EMC95903.1 - 1.8e-13 50.6 0.1 2.4e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF871 PF05913.11 EMC95903.1 - 0.096 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) DUF4489 PF14879.6 EMC95904.1 - 0.14 12.3 1.7 0.3 11.2 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) Med4 PF10018.9 EMC95905.1 - 8.1e-22 77.8 0.1 1.3e-21 77.2 0.0 1.4 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Metallophos PF00149.28 EMC95906.1 - 1.7e-13 51.5 0.7 3.1e-13 50.7 0.7 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMC95906.1 - 1.9e-06 28.2 0.0 0.00027 21.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain TRP PF06011.12 EMC95907.1 - 5.7e-130 433.9 13.8 7.9e-130 433.4 13.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EMC95907.1 - 2.4e-36 125.2 3.9 4.5e-36 124.3 3.9 1.5 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 EMC95907.1 - 0.00028 21.3 0.6 0.00052 20.4 0.6 1.4 1 0 0 1 1 1 1 ML domain Baculo_11_kDa PF06143.11 EMC95907.1 - 0.9 9.2 5.7 3.8 7.1 1.7 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF4267 PF14087.6 EMC95908.1 - 5.2e-18 65.2 0.5 6e-18 64.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) CH PF00307.31 EMC95909.1 - 8.3e-66 219.0 0.0 8.1e-17 61.4 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EMC95909.1 - 0.00031 21.1 0.5 0.0022 18.4 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 EMC95909.1 - 0.011 15.6 0.0 3.2 7.7 0.0 3.4 3 0 0 3 3 3 0 CAMSAP CH domain EF-hand_6 PF13405.6 EMC95909.1 - 0.071 13.1 3.7 0.98 9.5 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 EMC95909.1 - 0.19 11.3 0.7 7.6 6.3 0.1 2.8 2 0 0 2 2 2 0 EF hand GST_C_2 PF13410.6 EMC95910.1 - 4.3e-07 29.9 0.1 3.5e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EMC95910.1 - 0.003 17.3 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMC95910.1 - 0.0052 17.2 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMC95910.1 - 0.0075 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMC95910.1 - 0.082 13.1 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMC95910.1 - 0.088 13.1 0.0 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF1907 PF08925.11 EMC95913.1 - 2.4e-107 358.6 0.0 2.7e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) DLH PF01738.18 EMC95914.1 - 2e-31 109.2 0.1 2.4e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EMC95914.1 - 0.03 14.0 0.0 0.69 9.5 0.0 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC95914.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family UCH PF00443.29 EMC95915.1 - 2.2e-38 132.2 0.0 3e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EMC95915.1 - 7.6e-25 87.0 15.0 1.6e-20 73.2 1.5 3.8 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 EMC95915.1 - 1.6e-23 82.2 3.0 5.7e-23 80.4 0.3 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 EMC95915.1 - 2.2e-21 76.8 1.4 6.4e-18 65.4 0.0 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EMC95915.1 - 8e-21 73.6 0.1 1.6e-10 40.7 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.6 EMC95915.1 - 0.026 14.3 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain DUF5643 PF18705.1 EMC95915.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5643) zf-BED PF02892.15 EMC95915.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 BED zinc finger zf-RING_UBOX PF13445.6 EMC95915.1 - 9.2 6.4 11.4 13 5.9 3.5 3.6 3 0 0 3 3 3 0 RING-type zinc-finger Abhydrolase_1 PF00561.20 EMC95916.1 - 6.1e-24 85.0 0.2 8e-24 84.7 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC95916.1 - 2.2e-10 41.5 0.0 3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC95916.1 - 0.0018 17.6 0.0 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMC95916.1 - 0.2 10.3 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Rep_fac-A_C PF08646.10 EMC95917.1 - 2.3e-55 186.4 8.9 2.9e-54 182.8 4.4 3.2 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EMC95917.1 - 5.6e-36 122.4 0.2 1.5e-35 121.1 0.1 1.8 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EMC95917.1 - 1.3e-21 76.5 0.2 3.1e-21 75.3 0.2 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EMC95917.1 - 8.2e-14 51.4 0.4 3.2e-08 33.4 0.0 4.3 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain DUF4539 PF15072.6 EMC95917.1 - 3.3e-05 23.8 0.0 1.9 8.6 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4539) CDC24_OB3 PF17244.2 EMC95917.1 - 0.0022 17.8 0.8 0.47 10.1 0.1 3.5 4 0 0 4 4 4 1 Cell division control protein 24, OB domain 3 Zn_clus PF00172.18 EMC95918.1 - 3.5e-08 33.4 8.5 3.5e-08 33.4 8.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 EMC95919.1 - 1.6e-36 125.7 0.2 3.3e-23 82.4 0.0 3.4 2 2 2 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC95919.1 - 3.6e-32 111.0 0.3 8.4e-31 106.6 0.1 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EMC95919.1 - 0.046 13.0 0.0 0.046 13.0 0.0 3.2 2 1 2 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 EMC95919.1 - 0.08 11.7 0.1 0.22 10.3 0.0 1.6 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF2057 PF09829.9 EMC95919.1 - 0.92 9.6 10.8 1.8 8.7 7.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Ist1 PF03398.14 EMC95920.1 - 1.2e-62 210.6 2.9 1.5e-62 210.3 2.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF3094 PF11293.8 EMC95921.1 - 0.18 11.5 0.7 0.55 10.0 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) Mad3_BUB1_I PF08311.12 EMC95922.1 - 9.5e-44 148.4 0.6 2.4e-43 147.1 0.2 2.0 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EMC95922.1 - 3.5e-11 43.0 0.0 3.8e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.11 EMC95922.1 - 7.8e-10 38.8 0.0 8.5e-09 35.5 0.0 2.5 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 EMC95922.1 - 6.9e-05 22.3 0.0 0.00014 21.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 EMC95922.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein APH PF01636.23 EMC95922.1 - 0.0083 16.1 0.1 0.027 14.4 0.1 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 EMC95923.1 - 2.6e-62 205.3 12.3 2.4e-09 37.7 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC95923.1 - 7.3e-23 80.7 0.0 0.0062 16.8 0.0 6.1 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC95923.1 - 3.7e-08 32.5 2.2 0.022 13.4 0.0 4.8 3 2 3 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EMC95923.1 - 1.9e-07 30.4 0.2 1.5 7.7 0.0 5.1 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EMC95923.1 - 4e-07 30.1 0.0 0.0002 21.3 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EMC95923.1 - 4.4e-05 23.0 0.0 0.001 18.5 0.0 2.4 2 0 0 2 2 2 1 WD40-like domain PD40 PF07676.12 EMC95923.1 - 0.00039 20.3 0.3 4.8 7.2 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 EMC95923.1 - 0.0004 19.6 0.2 1 8.4 0.0 3.3 1 1 2 4 4 4 3 Protein of unknown function (DUF1513) VID27 PF08553.10 EMC95923.1 - 0.00058 19.0 0.1 0.063 12.3 0.0 3.1 3 1 1 4 4 4 2 VID27 C-terminal WD40-like domain Frtz PF11768.8 EMC95923.1 - 0.01 14.2 0.0 0.024 12.9 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Str_synth PF03088.16 EMC95923.1 - 0.013 15.6 0.0 0.3 11.3 0.0 2.9 3 1 1 4 4 4 0 Strictosidine synthase PALB2_WD40 PF16756.5 EMC95923.1 - 0.048 12.6 1.9 0.4 9.6 0.1 3.0 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain PCI PF01399.27 EMC95924.1 - 2.6e-05 24.6 0.0 9e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain FA_desaturase PF00487.24 EMC95925.1 - 1.3e-23 84.2 28.9 1.3e-23 84.2 28.9 1.4 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EMC95925.1 - 6.6e-09 35.8 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFIID_20kDa PF03847.13 EMC95926.1 - 1.9e-22 79.5 0.0 2.6e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Asp PF00026.23 EMC95927.1 - 3e-111 371.8 0.1 3.5e-111 371.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMC95927.1 - 8.9e-16 58.6 0.9 2.1e-13 50.9 0.9 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EMC95927.1 - 0.00042 20.8 0.0 1 9.9 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EMC95927.1 - 0.0014 19.2 0.0 3.8 8.2 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EMC95927.1 - 0.011 15.5 0.0 0.073 12.8 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal GRAM PF02893.20 EMC95928.1 - 2.8e-32 111.0 0.3 2.1e-19 69.5 0.0 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 EMC95928.1 - 3.2e-27 95.3 0.0 5.9e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 EMC95928.1 - 2.8e-16 59.9 0.0 7.5e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EMC95928.1 - 2.2e-06 28.0 0.3 7.5e-06 26.3 0.3 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EMC95928.1 - 0.00042 20.4 0.0 0.00096 19.2 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EMC95928.1 - 0.0012 19.1 0.0 0.0033 17.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EMC95928.1 - 0.006 16.9 0.2 0.025 15.0 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 EMC95928.1 - 0.0086 14.9 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_2 PF08458.10 EMC95928.1 - 0.0093 16.3 0.1 0.027 14.8 0.1 1.7 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_6 PF15406.6 EMC95928.1 - 0.028 14.7 0.0 0.078 13.3 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 EMC95928.1 - 0.044 13.6 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_TFIIH PF08567.11 EMC95928.1 - 0.067 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain NUDIX PF00293.28 EMC95929.1 - 7.9e-07 29.2 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EMC95929.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) GatB_N PF02934.15 EMC95930.1 - 4e-97 324.9 0.0 5.3e-97 324.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EMC95930.1 - 1.8e-18 66.9 0.0 3.1e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 GatB domain CBP4 PF07960.11 EMC95930.1 - 0.17 11.7 1.4 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 CBP4 DUF839 PF05787.13 EMC95931.1 - 0.13 11.3 0.1 0.15 11.2 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) Carot_N PF09150.10 EMC95931.1 - 0.2 11.5 0.2 0.25 11.2 0.2 1.1 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal LSR PF05624.14 EMC95931.1 - 0.57 10.2 3.0 1.3 9.1 3.0 1.6 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Arf PF00025.21 EMC95932.1 - 1.3e-44 151.8 0.0 1.5e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EMC95932.1 - 3.6e-19 68.9 0.0 4.1e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC95932.1 - 6.3e-16 58.7 0.0 1.1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMC95932.1 - 1.7e-08 34.1 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EMC95932.1 - 1.3e-06 28.5 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EMC95932.1 - 2.1e-06 27.3 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EMC95932.1 - 0.00031 20.0 0.2 0.001 18.3 0.0 1.8 2 0 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 EMC95932.1 - 0.0016 18.0 0.0 0.0089 15.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EMC95932.1 - 0.02 14.4 0.2 0.04 13.4 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EMC95932.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 EMC95932.1 - 0.071 13.2 0.0 0.38 10.8 0.1 1.9 1 1 1 2 2 2 0 Dynamin family RNA_pol_Rpb2_6 PF00562.28 EMC95933.1 - 8.6e-110 367.4 0.1 2.5e-106 356.0 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EMC95933.1 - 2e-33 115.7 0.0 3.1e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EMC95933.1 - 3.4e-28 97.6 0.0 8.5e-28 96.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EMC95933.1 - 1.6e-26 93.1 0.0 3.2e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EMC95933.1 - 2.5e-24 85.0 0.0 5.5e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EMC95933.1 - 6.5e-15 55.3 0.0 3.9e-14 52.8 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 PT-HINT PF07591.11 EMC95933.1 - 0.093 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Pretoxin HINT domain DUF1218 PF06749.12 EMC95934.1 - 0.039 14.5 0.0 0.042 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Sulf_transp PF04143.14 EMC95934.1 - 0.1 12.1 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Sulphur transport ATP1G1_PLM_MAT8 PF02038.16 EMC95934.1 - 0.16 11.4 0.2 0.24 10.9 0.2 1.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Gram_pos_anchor PF00746.21 EMC95934.1 - 0.18 11.8 1.4 0.19 11.7 0.1 1.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Adaptin_N PF01602.20 EMC95935.1 - 8e-135 450.4 1.8 1e-134 450.0 1.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EMC95935.1 - 1.4e-66 223.5 0.5 1.3e-61 207.4 0.4 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMC95935.1 - 4e-16 59.2 6.4 1.2e-07 32.0 0.0 6.0 3 2 5 8 8 8 4 HEAT repeats HEAT PF02985.22 EMC95935.1 - 7.1e-14 50.7 4.1 0.0089 16.2 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat UNC45-central PF11701.8 EMC95935.1 - 0.00012 22.1 0.5 0.02 14.9 0.1 2.9 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 EMC95935.1 - 0.00014 22.2 4.3 0.92 10.1 0.0 6.1 6 1 1 7 7 7 1 HEAT-like repeat Arm PF00514.23 EMC95935.1 - 0.0018 18.3 2.1 3.4 7.9 0.1 4.9 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EMC95935.1 - 0.0035 16.9 0.4 0.53 9.8 0.0 3.6 3 1 1 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 EMC95935.1 - 0.0095 16.1 0.1 1.7 8.9 0.0 3.7 2 2 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 EMC95935.1 - 1.3 8.9 5.8 0.54 10.1 1.1 2.8 2 1 2 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF5310 PF17237.2 EMC95936.1 - 7.5e-21 73.7 0.9 8.4e-21 73.6 0.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Ribosomal_S17 PF00366.20 EMC95937.1 - 3.2e-19 68.8 2.5 3.2e-19 68.8 2.5 1.4 2 0 0 2 2 2 1 Ribosomal protein S17 Abhydrolase_6 PF12697.7 EMC95938.1 - 1.7e-14 55.0 1.7 7.9e-14 52.8 1.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC95938.1 - 3e-10 40.2 0.0 5.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC95938.1 - 2e-07 30.5 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 EMC95938.1 - 0.026 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Abhydrolase_2 PF02230.16 EMC95938.1 - 0.12 12.1 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 EMC95938.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Amidohydro_1 PF01979.20 EMC95939.1 - 7.9e-25 87.9 0.0 2.2e-24 86.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMC95939.1 - 2.6e-14 53.6 0.1 2.8e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF1917 PF08939.10 EMC95940.1 - 1.8e-52 178.9 0.0 2.2e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DNA_primase_S PF01896.19 EMC95941.1 - 1.4e-60 204.4 0.1 2.2e-60 203.7 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit PPP1R32 PF15691.5 EMC95941.1 - 0.18 10.8 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 32 PI-PLC-X PF00388.19 EMC95942.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Gly_transf_sug PF04488.15 EMC95943.1 - 8.6e-12 45.5 0.0 1.6e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EMC95943.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Cyt-b5 PF00173.28 EMC95944.1 - 4.7e-15 55.5 0.0 5.4e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.16 EMC95945.1 - 7.3e-33 113.9 31.2 7.3e-33 113.9 31.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1993 PF09351.10 EMC95946.1 - 1.4e-58 197.6 0.0 1.6e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) PXA PF02194.15 EMC95948.1 - 4.8e-29 101.6 0.5 1.1e-28 100.5 0.0 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EMC95948.1 - 1.6e-19 70.5 1.1 1.2e-18 67.7 0.0 3.0 3 1 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 EMC95948.1 - 9.9e-08 32.0 0.0 2.9e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 PX domain ERM PF00769.19 EMC95948.1 - 0.01 15.7 11.2 0.024 14.5 11.2 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Macoilin PF09726.9 EMC95948.1 - 1.9 6.9 6.1 3 6.3 6.1 1.2 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 EMC95948.1 - 4 6.7 24.6 0.17 11.2 16.7 2.3 2 0 0 2 2 2 0 BUD22 tRNA-synt_1b PF00579.25 EMC95949.1 - 1.8e-57 194.9 0.0 2.3e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MCM PF00493.23 EMC95950.1 - 1.4e-100 335.0 0.0 2e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMC95950.1 - 2.8e-38 130.6 0.0 5.3e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EMC95950.1 - 9.8e-32 110.4 34.0 9.8e-32 110.4 34.0 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 EMC95950.1 - 3.3e-14 53.3 0.0 1e-13 51.7 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 EMC95950.1 - 5.3e-10 39.6 0.1 1.4e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EMC95950.1 - 1.7e-08 34.1 0.0 1.9e-06 27.4 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMC95950.1 - 4.7e-06 26.6 0.1 2.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EMC95950.1 - 0.00038 20.3 0.0 0.0023 17.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EMC95950.1 - 0.0019 17.9 0.2 0.013 15.2 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 EMC95950.1 - 0.05 13.3 0.3 0.099 12.4 0.3 1.4 1 0 0 1 1 1 0 AAA domain SelR PF01641.18 EMC95950.1 - 0.17 12.0 0.0 20 5.3 0.1 2.4 2 0 0 2 2 2 0 SelR domain zf-TFIIB PF13453.6 EMC95950.1 - 0.53 9.7 1.8 1.1 8.7 1.8 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.20 EMC95951.1 - 7.7e-13 48.4 7.5 7.7e-13 48.4 7.5 3.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) DNA_photolyase PF00875.18 EMC95951.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 DNA photolyase Aldo_ket_red PF00248.21 EMC95952.1 - 5.3e-55 186.7 0.0 5.9e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MIF4G PF02854.19 EMC95955.1 - 9.3e-24 84.2 0.1 7.8e-23 81.2 0.2 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 EMC95955.1 - 1.6e-16 60.3 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 MA3 domain CDV3 PF15359.6 EMC95955.1 - 1.6 9.2 6.5 0.15 12.6 1.1 2.1 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Nucleo_P87 PF07267.11 EMC95955.1 - 5.8 5.6 6.9 11 4.7 6.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SRP14 PF02290.15 EMC95956.1 - 2.6e-28 98.2 1.2 3.2e-28 97.9 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Vir_act_alpha_C PF10400.9 EMC95956.1 - 0.17 12.6 0.1 0.56 10.9 0.1 1.7 2 0 0 2 2 2 0 Virulence activator alpha C-term AC_N PF16214.5 EMC95958.1 - 3.6 6.6 5.8 5.2 6.1 5.8 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Drc1-Sld2 PF11719.8 EMC95959.1 - 2.1e-75 255.0 14.7 2.4e-75 254.8 14.7 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein COG6 PF06419.11 EMC95960.1 - 1.2e-200 667.9 5.4 1.4e-200 667.8 5.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 EMC95960.1 - 0.00063 19.8 3.3 0.0019 18.3 0.7 3.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 EMC95960.1 - 0.011 16.0 0.2 0.11 12.8 0.1 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF445 PF04286.12 EMC95960.1 - 0.022 14.6 5.1 0.22 11.3 0.1 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF445) Syntaxin-6_N PF09177.11 EMC95960.1 - 1.2 9.7 5.6 17 6.0 0.0 4.2 4 1 0 4 4 4 0 Syntaxin 6, N-terminal ZapB PF06005.12 EMC95960.1 - 4.5 7.8 8.5 0.3 11.6 0.5 3.3 4 0 0 4 4 4 0 Cell division protein ZapB Septum_form PF13845.6 EMC95961.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Septum formation RasGAP PF00616.19 EMC95963.1 - 2.2e-56 190.9 0.1 6.8e-56 189.3 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EMC95963.1 - 1.8e-30 105.9 1.1 1.8e-30 105.9 1.1 2.3 3 0 0 3 3 3 1 RasGAP C-terminus Mis14 PF08641.12 EMC95965.1 - 1.4e-20 74.0 1.6 1.4e-20 74.0 1.6 2.1 2 0 0 2 2 2 1 Kinetochore protein Mis14 like COMMD1_N PF17221.3 EMC95965.1 - 0.024 15.0 2.5 1.2 9.4 0.8 2.3 1 1 0 2 2 2 0 COMMD1 N-terminal domain Cep57_MT_bd PF06657.13 EMC95965.1 - 0.12 12.8 2.7 0.25 11.8 0.1 2.9 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF3138 PF11336.8 EMC95965.1 - 0.19 10.3 2.3 0.25 9.9 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4407 PF14362.6 EMC95965.1 - 0.46 9.8 10.0 0.28 10.5 8.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HSCB_C PF07743.13 EMC95965.1 - 5.6 7.5 8.1 1 9.9 0.9 3.1 2 2 1 3 3 3 0 HSCB C-terminal oligomerisation domain Glyco_transf_24 PF18404.1 EMC95967.1 - 1.5e-148 493.5 3.1 2.3e-148 492.9 3.1 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EMC95967.1 - 6.7e-71 239.2 0.0 2.6e-70 237.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EMC95967.1 - 1.1e-44 152.6 0.0 2.8e-44 151.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EMC95967.1 - 8.1e-44 148.8 3.6 1.6e-42 144.6 0.5 3.7 5 0 0 5 5 5 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EMC95967.1 - 3.8e-42 142.8 0.0 7.5e-42 141.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 EMC95967.1 - 6.3e-34 117.8 0.0 6e-32 111.3 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EMC95967.1 - 0.0026 17.3 0.1 0.0045 16.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1772 PF08592.11 EMC95968.1 - 2.9e-30 105.4 2.5 4.7e-30 104.7 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) GPHR_N PF12537.8 EMC95968.1 - 8.3 6.6 6.9 1.1 9.4 0.2 2.8 4 0 0 4 4 4 0 The Golgi pH Regulator (GPHR) Family N-terminal MSC PF09402.10 EMC95969.1 - 1.7e-103 346.6 0.0 2.6e-103 346.1 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EMC95969.1 - 9e-18 63.7 0.0 2.2e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 EMC95969.1 - 0.00058 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein Endonuc-dimeris PF09124.10 EMC95969.1 - 0.05 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation zf-RING_2 PF13639.6 EMC95970.1 - 7.3e-05 23.0 0.7 0.00023 21.4 0.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EMC95970.1 - 0.00049 20.0 0.8 0.002 18.1 0.8 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMC95970.1 - 0.022 14.6 1.2 0.022 14.6 1.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC95970.1 - 0.032 14.1 0.4 0.032 14.1 0.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf_C2H2_13 PF18508.1 EMC95970.1 - 0.09 12.4 0.2 0.09 12.4 0.2 1.9 2 0 0 2 2 2 0 Zinc finger domain zf_UBZ PF18439.1 EMC95970.1 - 0.15 11.6 3.0 9.6 5.9 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 EMC95970.1 - 0.2 11.1 4.5 4.4 6.9 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 EMC95970.1 - 0.5 10.3 2.5 0.56 10.1 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC95970.1 - 0.69 9.8 4.7 0.16 11.9 0.9 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Nudix_N_2 PF14803.6 EMC95970.1 - 0.76 9.7 6.1 0.32 11.0 0.4 2.8 3 0 0 3 3 3 0 Nudix N-terminal DDHD PF02862.17 EMC95971.1 - 7e-62 209.5 0.0 6.8e-61 206.3 0.0 2.4 2 0 0 2 2 2 1 DDHD domain DUF676 PF05057.14 EMC95971.1 - 0.14 11.6 0.1 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) 4HBT PF03061.22 EMC95972.1 - 1.3e-10 41.5 0.1 2.2e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Crystall PF00030.19 EMC95973.1 - 0.039 14.1 0.0 0.043 14.0 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin KilA-N PF04383.13 EMC95975.1 - 4.4e-05 23.3 0.0 0.00084 19.2 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain ODC_AZ PF02100.17 EMC95976.1 - 2.7e-42 143.4 0.1 4.2e-42 142.7 0.1 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Myb_DNA-binding PF00249.31 EMC95977.1 - 2e-22 79.1 9.5 2.2e-14 53.3 1.7 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC95977.1 - 1.6e-13 50.7 7.8 1.8e-12 47.3 2.5 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EMC95977.1 - 0.00018 21.8 8.0 0.017 15.5 2.4 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 EMC95977.1 - 0.015 15.4 0.0 0.2 11.8 0.5 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 EMC95977.1 - 0.036 14.4 2.9 5.7 7.3 0.3 2.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Anoctamin PF04547.12 EMC95978.1 - 0.055 12.3 2.8 0.083 11.7 1.7 1.7 2 0 0 2 2 2 0 Calcium-activated chloride channel DUF4181 PF13789.6 EMC95978.1 - 1 9.7 6.4 5.4 7.3 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) PAP2 PF01569.21 EMC95978.1 - 1.4 8.7 10.2 0.33 10.7 0.8 2.1 2 0 0 2 2 2 0 PAP2 superfamily Gram_pos_anchor PF00746.21 EMC95980.1 - 0.15 12.0 2.8 0.46 10.5 2.8 1.9 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Yip1 PF04893.17 EMC95982.1 - 0.025 14.3 0.3 0.045 13.5 0.3 1.3 1 0 0 1 1 1 0 Yip1 domain Rick_17kDa_Anti PF05433.15 EMC95982.1 - 0.21 11.5 9.4 0.36 10.7 9.4 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EMC95982.1 - 0.3 11.1 8.7 0.55 10.3 8.7 1.3 1 0 0 1 1 1 0 Glycine zipper HSP70 PF00012.20 EMC95983.1 - 0.00013 20.3 0.0 0.00025 19.4 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMC95983.1 - 0.0059 15.5 0.0 0.051 12.4 0.0 2.2 2 1 0 2 2 2 1 MreB/Mbl protein DUF5344 PF17279.2 EMC95983.1 - 0.18 12.4 0.0 0.6 10.7 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Cir_N PF10197.9 EMC95987.1 - 2.8e-06 27.4 2.8 2.8e-06 27.4 2.8 3.2 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR RRM_1 PF00076.22 EMC95989.1 - 1.6e-31 107.9 0.3 1.5e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC95989.1 - 1.2e-09 38.2 0.1 0.0014 18.7 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EMC95989.1 - 0.012 15.6 0.0 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EMC95989.1 - 0.063 13.3 0.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RabGAP-TBC PF00566.18 EMC95992.1 - 1.1e-49 169.0 0.0 1.9e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain dCMP_cyt_deam_1 PF00383.23 EMC95993.1 - 1.1e-25 89.4 1.9 1.9e-25 88.6 1.9 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMC95993.1 - 7.7e-09 35.4 0.6 1.2e-08 34.7 0.2 1.6 2 0 0 2 2 2 1 MafB19-like deaminase AAA_18 PF13238.6 EMC95993.1 - 0.0013 19.3 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Myf5 PF12232.8 EMC95995.1 - 0.018 15.8 0.4 0.018 15.8 0.4 1.9 2 0 0 2 2 2 0 Myogenic determination factor 5 F-box-like PF12937.7 EMC95996.1 - 0.11 12.4 1.0 0.73 9.8 0.0 2.7 3 0 0 3 3 3 0 F-box-like DUF1100 PF06500.11 EMC95998.1 - 8.3e-15 54.5 0.0 1.1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 EMC95998.1 - 2.6e-06 27.3 0.3 5e-05 23.1 0.1 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC95998.1 - 1.4e-05 25.8 0.1 2.7e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EMC95998.1 - 4.1e-05 23.4 0.0 0.00022 21.0 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EMC95998.1 - 0.00023 20.5 0.0 0.00037 19.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EMC95998.1 - 0.0011 18.6 0.2 0.0026 17.4 0.1 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 EMC95998.1 - 0.0018 18.3 0.0 0.0036 17.2 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal USP8_dimer PF08969.11 EMC95998.1 - 0.023 14.9 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain Abhydrolase_2 PF02230.16 EMC95998.1 - 0.032 14.0 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EMC95998.1 - 0.057 12.9 0.1 0.18 11.2 0.1 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 EMC95998.1 - 0.19 11.2 0.0 1.1 8.8 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S58 PF03576.14 EMC95998.1 - 0.3 10.6 0.0 0.43 10.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S58 DUF4398 PF14346.6 EMC95998.1 - 0.42 11.3 2.5 0.72 10.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF1771 PF08590.10 EMC95998.1 - 6.3 7.3 6.4 22 5.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) OST3_OST6 PF04756.13 EMC95999.1 - 8.4e-106 353.6 0.0 1e-105 353.3 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Filament PF00038.21 EMC96000.1 - 1.8 8.0 66.7 0.44 10.1 47.7 2.6 1 1 1 2 2 2 0 Intermediate filament protein DUF2722 PF10846.8 EMC96001.1 - 6.8e-09 35.2 1.3 6.8e-09 35.2 1.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.18 EMC96002.1 - 1.1e-33 116.7 0.0 2.2e-33 115.7 0.0 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Tannase PF07519.11 EMC96003.1 - 1.1e-91 308.2 2.9 8e-91 305.3 2.9 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EMC96003.1 - 0.0074 15.8 0.1 0.21 11.0 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Cytochrom_B561 PF03188.16 EMC96004.1 - 9.8e-18 64.6 10.3 9.8e-18 64.6 10.3 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF5630 PF18632.1 EMC96004.1 - 0.05 12.9 0.2 0.087 12.1 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5630) SdpI PF13630.6 EMC96004.1 - 0.072 13.2 0.8 0.072 13.2 0.8 3.3 2 1 0 2 2 2 0 SdpI/YhfL protein family HypF_C PF17788.1 EMC96004.1 - 0.11 13.2 2.5 0.23 12.2 1.4 2.1 2 0 0 2 2 2 0 HypF Kae1-like domain SLATT_3 PF18184.1 EMC96004.1 - 1.6 8.8 4.4 0.5 10.5 0.1 2.1 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 3 DUF3619 PF12279.8 EMC96004.1 - 2.7 8.3 4.5 7.3 6.9 0.3 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3619) YIF1 PF03878.15 EMC96004.1 - 6.1 6.3 8.9 6.6 6.2 0.6 2.6 2 1 1 3 3 3 0 YIF1 VTC PF09359.10 EMC96005.1 - 7.3e-100 333.9 0.1 7.3e-100 333.9 0.1 2.1 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 EMC96005.1 - 1.2e-14 55.1 21.7 2.3e-06 27.8 0.1 4.2 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 EMC96005.1 - 8.8e-12 45.3 5.7 1.6e-11 44.4 5.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Herpes_UL25 PF01499.16 EMC96005.1 - 0.069 11.7 2.0 0.12 10.9 2.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family AbiH PF14253.6 EMC96005.1 - 0.11 12.4 3.1 0.27 11.1 3.1 1.6 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Host_attach PF10116.9 EMC96005.1 - 0.51 10.9 5.1 1.4 9.5 0.2 2.8 2 0 0 2 2 2 0 Protein required for attachment to host cells RrnaAD PF00398.20 EMC96006.1 - 2.7e-61 207.0 0.0 8.6e-61 205.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EMC96006.1 - 5.6e-08 33.4 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC96006.1 - 3.9e-05 24.2 0.0 8.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC96006.1 - 0.00017 21.5 0.0 0.00036 20.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EMC96006.1 - 0.00058 19.7 0.0 0.00091 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EMC96006.1 - 0.00058 20.5 0.0 0.0016 19.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC96006.1 - 0.0031 17.1 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EMC96006.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 EMC96006.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 EMC96006.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.20 EMC96006.1 - 0.068 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF5401 PF17380.2 EMC96006.1 - 1.1 7.3 4.5 1.2 7.2 2.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5401) IATP PF04568.12 EMC96007.1 - 2.6e-19 69.5 1.5 3.3e-19 69.1 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PriC PF07445.12 EMC96007.1 - 0.0087 16.0 0.6 0.01 15.8 0.6 1.1 1 0 0 1 1 1 1 Primosomal replication protein priC Hexokinase_2 PF03727.16 EMC96008.1 - 3.7e-84 281.9 0.0 8.2e-84 280.8 0.0 1.6 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 EMC96008.1 - 8e-71 238.0 0.0 2.5e-70 236.4 0.0 1.8 2 0 0 2 2 2 1 Hexokinase Ribosomal_L19e PF01280.20 EMC96008.1 - 7.6e-49 165.5 9.8 7.6e-49 165.5 9.8 2.3 2 1 0 2 2 2 1 Ribosomal protein L19e TRAP-gamma PF07074.12 EMC96008.1 - 0.79 9.3 4.4 1.3 8.6 4.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Gcn1_N PF12074.8 EMC96009.1 - 1.2e-110 370.2 5.2 9.2e-110 367.3 1.0 4.1 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EMC96009.1 - 3.2e-31 104.7 39.2 0.18 12.2 0.0 21.6 22 0 0 22 22 20 8 HEAT repeat HEAT_EZ PF13513.6 EMC96009.1 - 1.9e-26 92.1 60.7 0.0002 21.8 0.0 21.2 18 3 5 23 23 22 8 HEAT-like repeat HEAT_2 PF13646.6 EMC96009.1 - 1.9e-24 85.8 49.3 1.9e-05 25.0 0.9 15.7 12 3 6 19 19 18 10 HEAT repeats Cnd1 PF12717.7 EMC96009.1 - 4.6e-14 52.8 6.4 0.12 12.5 0.0 9.7 5 2 3 9 9 9 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EMC96009.1 - 2.3e-11 44.2 0.2 0.0037 17.4 0.0 6.9 8 1 1 9 9 8 2 Parkin co-regulated protein CLASP_N PF12348.8 EMC96009.1 - 1.9e-09 37.4 0.0 1.3 8.6 0.0 7.6 5 3 2 7 7 7 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 EMC96009.1 - 3.9e-09 37.0 0.0 3 8.5 0.0 8.7 8 2 3 11 11 10 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EMC96009.1 - 8.9e-06 24.5 13.6 0.45 9.0 0.3 7.6 8 1 0 8 8 8 2 Adaptin N terminal region IFRD PF05004.13 EMC96009.1 - 0.00086 18.5 27.0 0.012 14.8 2.8 7.9 8 1 1 9 9 9 2 Interferon-related developmental regulator (IFRD) TIP120 PF08623.10 EMC96009.1 - 0.0012 18.6 0.0 2.1 8.1 0.0 5.5 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) MMS19_C PF12460.8 EMC96009.1 - 0.012 14.8 0.1 0.012 14.8 0.1 8.4 9 3 2 11 11 11 0 RNAPII transcription regulator C-terminal RasGEF_N_2 PF14663.6 EMC96009.1 - 0.016 15.6 0.2 3.9 7.9 0.0 4.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Tti2 PF10521.9 EMC96009.1 - 0.038 13.5 7.1 1.7 8.1 0.0 5.8 8 0 0 8 8 8 0 Tti2 family RIX1 PF08167.12 EMC96009.1 - 0.095 12.4 10.7 1.6 8.4 0.7 5.6 5 2 0 5 5 5 0 rRNA processing/ribosome biogenesis DUF937 PF06078.11 EMC96009.1 - 0.11 13.0 14.4 42 4.7 0.0 7.0 6 2 1 7 7 5 0 Bacterial protein of unknown function (DUF937) DUF3437 PF11919.8 EMC96009.1 - 0.18 11.7 0.1 34 4.4 0.0 5.0 5 0 0 5 5 4 0 Domain of unknown function (DUF3437) WASH-7_C PF14746.6 EMC96009.1 - 0.2 11.3 0.9 0.57 9.9 0.9 1.7 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal ADSL_C PF10397.9 EMC96009.1 - 1.3 9.7 4.9 76 4.0 0.0 5.3 4 1 1 5 5 5 0 Adenylosuccinate lyase C-terminus RTP1_C1 PF10363.9 EMC96009.1 - 1.4 9.1 12.4 59 3.9 0.1 6.8 9 0 0 9 9 7 0 Required for nuclear transport of RNA pol II C-terminus 1 U3snoRNP10 PF12397.8 EMC96009.1 - 6 7.3 11.3 35 4.8 0.0 5.9 5 0 0 5 5 5 0 U3 small nucleolar RNA-associated protein 10 HA2 PF04408.23 EMC96010.1 - 5.1e-16 58.9 0.1 1.5e-15 57.4 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMC96010.1 - 1.8e-15 57.2 0.0 4.4e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMC96010.1 - 4.7e-12 46.0 0.4 8.9e-12 45.1 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EMC96010.1 - 1.6e-06 28.4 0.3 1e-05 25.8 0.3 2.4 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 EMC96010.1 - 0.00019 21.7 0.0 0.00045 20.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Transp_inhibit PF18791.1 EMC96010.1 - 0.0099 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Transport inhibitor response 1 protein domain AAA_30 PF13604.6 EMC96010.1 - 0.038 13.7 0.1 0.094 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EMC96010.1 - 0.042 12.9 0.0 0.095 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HEM4 PF02602.15 EMC96011.1 - 4.2e-38 131.0 0.0 1.2e-37 129.5 0.0 1.7 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.13 EMC96012.1 - 2.1e-30 105.1 6.6 3.1e-30 104.6 4.5 2.0 2 0 0 2 2 2 1 Erv1 / Alr family Proteasome PF00227.26 EMC96014.1 - 5.7e-47 159.7 0.3 6.8e-47 159.4 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit THOC7 PF05615.13 EMC96015.1 - 2.3e-39 134.7 6.6 2.3e-39 134.7 6.6 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 TPR_MLP1_2 PF07926.12 EMC96015.1 - 0.04 14.0 9.8 0.078 13.0 9.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CTD PF12815.7 EMC96015.1 - 0.068 13.7 0.8 0.13 12.9 0.8 1.4 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Fez1 PF06818.15 EMC96015.1 - 0.074 13.5 8.4 0.16 12.4 8.4 1.6 1 0 0 1 1 1 0 Fez1 DUF4570 PF15134.6 EMC96015.1 - 0.26 11.3 4.2 0.51 10.4 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF241 PF03087.14 EMC96015.1 - 0.26 11.1 4.9 0.5 10.2 4.9 1.5 1 1 0 1 1 1 0 Arabidopsis protein of unknown function NYD-SP28_assoc PF14775.6 EMC96015.1 - 1.3 9.2 5.2 2.8 8.1 0.3 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain HD PF01966.22 EMC96016.1 - 4.7e-09 36.5 0.6 8.2e-09 35.7 0.6 1.4 1 0 0 1 1 1 1 HD domain DNA_ligase_A_N PF04675.14 EMC96017.1 - 0.03 14.6 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 DNA ligase N terminus TPP_enzyme_N PF02776.18 EMC96018.1 - 4e-37 127.5 0.7 1e-36 126.2 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMC96018.1 - 2.2e-22 79.5 0.3 7.1e-22 77.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMC96018.1 - 9.6e-17 61.0 0.0 2.1e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DLH PF01738.18 EMC96020.1 - 2.8e-17 63.0 0.0 1.2e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family LAT PF15234.6 EMC96020.1 - 0.028 14.2 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells 3HCDH PF00725.22 EMC96020.1 - 0.12 13.0 0.0 1.6 9.4 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain polyprenyl_synt PF00348.17 EMC96021.1 - 9.1e-53 178.9 0.1 2.3e-52 177.6 0.0 1.7 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 EMC96021.1 - 3.2e-06 26.7 1.0 0.039 13.3 0.0 2.2 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain CA_like PF10563.9 EMC96021.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative carbonic anhydrase Glyco_hydro_28 PF00295.17 EMC96022.1 - 1.3e-96 323.5 23.4 1.6e-96 323.2 23.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NPL PF17800.1 EMC96023.1 - 1.3e-32 112.5 1.4 1.3e-32 112.5 1.4 3.0 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 EMC96023.1 - 2.1e-32 111.3 0.0 5.4e-32 110.0 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Solute_trans_a PF03619.16 EMC96024.1 - 5.2e-56 190.1 14.4 6.3e-56 189.8 14.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 EMC96024.1 - 0.024 14.9 7.0 0.056 13.7 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) LapA_dom PF06305.11 EMC96024.1 - 0.29 11.0 3.2 0.35 10.7 1.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ferric_reduct PF01794.19 EMC96024.1 - 2 8.6 5.7 24 5.0 0.1 2.7 2 1 1 3 3 3 0 Ferric reductase like transmembrane component SAP130_C PF16014.5 EMC96027.1 - 3.9 6.5 7.5 4.8 6.2 7.5 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus PRR18 PF15671.5 EMC96027.1 - 4.5 7.1 7.8 5.2 6.9 7.8 1.1 1 0 0 1 1 1 0 Proline-rich protein family 18 FUSC_2 PF13515.6 EMC96028.1 - 2.2e-28 98.9 5.3 2.2e-28 98.9 5.3 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 EMC96028.1 - 3.3e-08 32.8 12.4 7.1e-06 25.1 10.5 3.1 2 1 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 EMC96028.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 KdpC PF02669.15 EMC96028.1 - 0.025 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 K+-transporting ATPase, c chain FUSC PF04632.12 EMC96028.1 - 0.063 11.8 11.0 0.18 10.3 0.1 3.1 4 0 0 4 4 4 0 Fusaric acid resistance protein family ER_lumen_recept PF00810.18 EMC96029.1 - 1.9e-55 187.7 2.9 2.9e-55 187.1 2.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EMC96029.1 - 0.086 12.6 7.6 2.7 7.8 0.2 3.4 4 0 0 4 4 4 0 PQ loop repeat DUF485 PF04341.12 EMC96029.1 - 0.26 11.3 4.1 0.54 10.2 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF485 TFIID-18kDa PF02269.16 EMC96030.1 - 2.6e-28 97.9 0.5 1.2e-27 95.7 0.2 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 EMC96030.1 - 0.0035 17.6 0.1 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TP_methylase PF00590.20 EMC96031.1 - 1.1e-23 84.3 0.1 2e-23 83.4 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2235 PF09994.9 EMC96032.1 - 4.8e-93 311.7 0.6 6.7e-93 311.2 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 EMC96034.1 - 1.1e-41 143.0 0.1 1.2e-26 93.5 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EMC96034.1 - 3.1e-08 32.8 0.0 5.7e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DWNN PF08783.11 EMC96035.1 - 2.6e-28 98.1 0.1 7.5e-28 96.6 0.1 1.8 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 EMC96035.1 - 7.8e-11 41.6 6.4 1.5e-10 40.7 6.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 EMC96035.1 - 6.1e-05 22.8 5.7 6.1e-05 22.8 5.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC96035.1 - 0.00017 21.5 4.4 0.00036 20.5 4.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 EMC96035.1 - 0.00036 20.3 1.0 0.00094 19.0 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 EMC96035.1 - 0.003 17.9 4.7 0.003 17.9 4.7 1.7 2 0 0 2 2 1 1 Ring finger domain zf-CCHC PF00098.23 EMC96035.1 - 0.003 17.6 2.8 0.003 17.6 2.8 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4 PF00097.25 EMC96035.1 - 0.0054 16.6 4.7 0.011 15.6 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EMC96035.1 - 0.0083 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-CCHC_3 PF13917.6 EMC96035.1 - 0.013 15.4 0.5 0.035 14.1 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_4 PF15227.6 EMC96035.1 - 0.054 13.7 6.2 0.13 12.5 6.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EMC96035.1 - 0.056 13.2 4.3 0.12 12.2 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 EMC96035.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.3 3 0 0 3 3 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 EMC96035.1 - 0.2 11.5 9.0 0.027 14.3 3.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 EMC96035.1 - 0.21 11.6 2.9 1.4 9.0 1.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 EMC96035.1 - 0.46 10.1 1.3 21 4.8 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-dskA_traR PF01258.17 EMC96035.1 - 2.6 8.1 9.6 1.9 8.5 0.1 3.4 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zf-RING_5 PF14634.6 EMC96035.1 - 7 6.7 10.2 0.44 10.5 3.9 2.1 2 0 0 2 2 2 0 zinc-RING finger domain RED_N PF07808.13 EMC96036.1 - 1.1e-07 31.7 4.1 2.9e-07 30.3 4.1 1.7 1 0 0 1 1 1 1 RED-like protein N-terminal region Amnionless PF14828.6 EMC96037.1 - 0.086 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless BatD PF13584.6 EMC96037.1 - 0.16 10.7 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance Peptidase_M56 PF05569.11 EMC96037.1 - 0.19 10.9 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Vps16_N PF04841.13 EMC96039.1 - 0.13 11.0 0.2 0.19 10.5 0.2 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region Ribosomal_L44 PF00935.19 EMC96040.1 - 3.7e-36 123.5 12.6 3.7e-36 123.5 12.6 2.3 3 0 0 3 3 3 1 Ribosomal protein L44 Ribosomal_L33 PF00471.20 EMC96040.1 - 0.29 11.6 12.8 5.8 7.4 1.4 3.4 2 1 0 2 2 2 0 Ribosomal protein L33 HypA PF01155.19 EMC96040.1 - 3.8 7.6 8.8 7.7 6.6 0.1 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RWD PF05773.22 EMC96041.1 - 0.1 12.9 0.1 1 9.7 0.0 2.5 2 2 0 2 2 2 0 RWD domain Pkinase PF00069.25 EMC96043.1 - 6.4e-69 232.2 0.0 7.7e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC96043.1 - 2.1e-32 112.4 0.0 2.7e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMC96043.1 - 0.0003 20.2 0.2 0.00048 19.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMC96043.1 - 0.003 16.6 0.5 0.006 15.6 0.5 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EMC96043.1 - 0.004 16.5 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMC96043.1 - 0.02 14.8 0.2 0.074 13.0 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EMC96043.1 - 0.051 12.6 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MRJP PF03022.16 EMC96044.1 - 1.6e-27 96.6 0.0 2.1e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 EMC96044.1 - 7.4e-05 22.4 0.2 0.00072 19.2 0.1 2.3 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Helicase_C_2 PF13307.6 EMC96045.1 - 4.2e-55 186.5 0.0 7.8e-55 185.7 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EMC96045.1 - 6.1e-49 166.0 0.0 1e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EMC96045.1 - 0.00046 20.2 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EMC96045.1 - 0.0051 16.6 0.0 0.84 9.4 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Vma12 PF11712.8 EMC96046.1 - 2.6e-43 147.4 0.0 3.6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PMP1_2 PF08114.11 EMC96046.1 - 4.5 7.1 5.5 22 4.9 0.1 2.5 2 0 0 2 2 2 0 ATPase proteolipid family polyprenyl_synt PF00348.17 EMC96047.1 - 3.2e-70 236.1 0.0 5.3e-70 235.4 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase DUF3659 PF12396.8 EMC96047.1 - 0.13 12.2 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Ank_5 PF13857.6 EMC96048.1 - 3.1e-20 72.0 2.8 2.1e-09 37.4 0.2 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMC96048.1 - 3.5e-20 72.4 1.3 3.2e-10 40.4 0.1 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC96048.1 - 1.6e-14 54.1 0.6 7.6e-06 26.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC96048.1 - 3.3e-13 48.5 1.5 0.00089 19.5 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EMC96048.1 - 8.3e-12 45.0 4.7 2.3e-05 24.6 0.9 3.9 4 0 0 4 4 4 3 Ankyrin repeat UQ_con PF00179.26 EMC96049.1 - 1.5e-52 176.9 0.0 1.7e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMC96049.1 - 0.0049 16.6 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMC96049.1 - 0.036 14.3 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EMC96049.1 - 0.046 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.25 EMC96050.1 - 1.6e-40 139.1 0.2 5.3e-18 65.3 0.0 4.1 3 1 1 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 EMC96050.1 - 3.9e-19 68.9 0.1 1.1e-06 28.1 0.0 4.0 3 1 1 4 4 4 3 Protein tyrosine kinase APH PF01636.23 EMC96050.1 - 0.1 12.5 0.3 0.1 12.5 0.3 2.1 2 2 0 2 2 2 0 Phosphotransferase enzyme family KAR9 PF08580.10 EMC96051.1 - 7.2e-148 494.1 4.7 7.2e-148 494.1 4.7 2.0 2 1 0 2 2 2 1 Yeast cortical protein KAR9 PLU-1 PF08429.11 EMC96051.1 - 0.03 13.5 0.4 1.5 7.9 0.0 2.6 3 0 0 3 3 3 0 PLU-1-like protein Kelch_5 PF13854.6 EMC96052.1 - 2e-15 56.4 5.3 2.8e-10 39.9 0.1 4.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 EMC96052.1 - 2.3e-08 33.9 12.2 0.026 14.5 0.4 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EMC96052.1 - 1.9e-07 30.5 10.1 0.00055 19.5 0.9 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EMC96052.1 - 1.4e-06 28.3 13.1 0.034 14.4 0.1 4.8 3 1 1 4 4 4 3 Kelch motif SKG6 PF08693.10 EMC96052.1 - 0.00049 19.5 0.7 0.0018 17.7 0.7 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_2 PF07646.15 EMC96052.1 - 0.032 14.2 8.4 0.051 13.6 0.5 4.5 3 1 0 3 3 3 0 Kelch motif Amnionless PF14828.6 EMC96052.1 - 0.15 10.9 0.0 0.31 9.8 0.0 1.5 1 0 0 1 1 1 0 Amnionless YajC PF02699.15 EMC96052.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Syndecan PF01034.20 EMC96052.1 - 0.85 9.6 2.5 1.9 8.4 2.5 1.5 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 EMC96052.1 - 1.8 8.4 7.7 3.4 7.5 7.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Fringe PF02434.16 EMC96054.1 - 0.0037 16.7 0.3 0.043 13.3 0.3 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 EMC96054.1 - 0.015 15.2 2.6 0.044 13.7 2.6 1.7 1 0 0 1 1 1 0 PAN domain PGM_PMM_I PF02878.16 EMC96055.1 - 3.2e-38 130.5 0.0 5.4e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EMC96055.1 - 1.1e-20 74.1 0.0 2.6e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EMC96055.1 - 4.2e-13 49.5 0.0 7.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EMC96055.1 - 5.8e-07 29.6 0.0 1.7e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Sec23_trunk PF04811.15 EMC96056.1 - 9.6e-49 166.1 0.0 3.6e-48 164.3 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EMC96056.1 - 1.1e-22 79.8 0.0 2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EMC96056.1 - 1.5e-17 63.3 4.8 3.6e-17 62.1 4.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EMC96056.1 - 1e-16 61.5 0.3 2e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 EMC96056.1 - 1.3e-07 31.4 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Aa_trans PF01490.18 EMC96057.1 - 6.5e-28 97.6 31.1 8.6e-28 97.2 31.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2684 PF10885.8 EMC96057.1 - 0.23 11.6 2.2 8.5 6.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2684) Sugar_tr PF00083.24 EMC96058.1 - 1.3e-75 255.0 17.8 1.6e-75 254.7 17.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC96058.1 - 4e-15 55.6 52.3 1.1e-08 34.4 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 EMC96060.1 - 0.00042 20.0 0.0 0.0013 18.3 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PrpF PF04303.13 EMC96062.1 - 3.5e-104 348.7 0.4 4e-104 348.5 0.4 1.0 1 0 0 1 1 1 1 PrpF protein CinA PF02464.17 EMC96063.1 - 2.3e-33 115.0 0.1 2.7e-33 114.7 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein ATG7_N PF16420.5 EMC96064.1 - 1.2e-112 376.5 0.0 1.5e-112 376.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EMC96064.1 - 3.1e-40 138.1 0.0 4.6e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Dynamitin PF04912.14 EMC96065.1 - 0.018 14.4 0.6 0.033 13.5 0.6 1.3 1 0 0 1 1 1 0 Dynamitin PepX_C PF08530.10 EMC96066.1 - 6.1e-28 98.3 0.0 3.1e-26 92.7 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EMC96066.1 - 7e-25 88.1 3.2 7e-18 65.2 0.1 3.0 2 1 1 3 3 3 3 X-Pro dipeptidyl-peptidase (S15 family) FAD_binding_3 PF01494.19 EMC96067.1 - 3e-66 224.1 0.2 1.3e-65 222.0 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC96067.1 - 1e-06 28.2 0.0 5.7e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC96067.1 - 7.5e-05 23.2 0.0 0.0052 17.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC96067.1 - 0.0026 18.0 0.1 0.0068 16.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMC96067.1 - 0.0032 16.6 0.1 0.43 9.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein TrkA_N PF02254.18 EMC96067.1 - 0.0036 17.6 0.0 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 EMC96067.1 - 0.012 15.3 0.0 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase XdhC_C PF13478.6 EMC96067.1 - 0.015 15.8 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Thi4 PF01946.17 EMC96067.1 - 0.049 12.9 0.1 0.18 11.0 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 EMC96067.1 - 0.065 12.5 0.1 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EMC96067.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lactamase_B_3 PF13483.6 EMC96068.1 - 2.2e-10 40.7 0.0 8.8e-06 25.7 0.0 2.5 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EMC96068.1 - 2.1e-06 27.4 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMC96068.1 - 1.6e-05 25.0 0.5 2.6e-05 24.3 0.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily TRI12 PF06609.13 EMC96069.1 - 1.1e-25 90.2 22.2 1.4e-25 89.8 22.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EMC96069.1 - 6.7e-23 81.2 54.0 8.6e-20 71.0 50.9 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4229 PF14012.6 EMC96069.1 - 0.096 12.8 0.4 0.096 12.8 0.4 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4229) DUF4179 PF13786.6 EMC96069.1 - 0.66 10.5 0.1 0.66 10.5 0.1 4.0 4 2 0 4 4 4 0 Domain of unknown function (DUF4179) adh_short PF00106.25 EMC96070.1 - 6.3e-44 149.8 0.0 1e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96070.1 - 5.3e-29 101.4 0.0 1.3e-28 100.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96070.1 - 2.1e-08 34.3 0.0 2.9e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMC96070.1 - 0.013 15.4 0.2 0.02 14.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EMC96070.1 - 0.096 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans PF04082.18 EMC96071.1 - 1.2e-10 40.8 0.2 2.4e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 6PGD PF00393.19 EMC96072.1 - 2.2e-127 424.4 0.0 2.9e-127 424.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EMC96072.1 - 9.4e-49 165.6 0.1 1.4e-48 165.1 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMC96072.1 - 0.16 12.2 0.3 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.22 EMC96073.1 - 5e-14 51.9 0.0 6.1e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N PF02798.20 EMC96075.1 - 4.3e-12 46.2 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMC96075.1 - 1e-11 44.8 0.0 2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMC96075.1 - 6.5e-11 42.3 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMC96075.1 - 8e-11 42.2 0.0 1.4e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMC96075.1 - 9.7e-09 35.4 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMC96075.1 - 1.4e-05 25.0 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCCH_2 PF14608.6 EMC96076.1 - 5.4e-13 48.9 56.6 0.00011 22.6 10.3 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger GET2 PF08690.10 EMC96076.1 - 1.3 8.6 7.7 2.9 7.5 7.7 1.6 1 0 0 1 1 1 0 GET complex subunit GET2 zf-CCCH_3 PF15663.5 EMC96076.1 - 2.7 8.3 13.9 21 5.4 5.8 3.8 1 1 1 2 2 2 0 Zinc-finger containing family WD40 PF00400.32 EMC96077.1 - 5.6e-06 27.0 0.8 8.3 7.5 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC96077.1 - 9.3e-05 22.7 0.0 11 6.4 0.2 5.1 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EMC96077.1 - 0.026 14.4 0.0 2.2 8.3 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Mago-bind PF09282.10 EMC96078.1 - 3.2e-14 52.5 3.9 6.2e-14 51.5 3.9 1.5 1 0 0 1 1 1 1 Mago binding PAPS_reduct PF01507.19 EMC96078.1 - 0.16 12.0 0.3 0.31 11.0 0.3 1.5 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family UCR_UQCRX_QCR9 PF05365.12 EMC96079.1 - 1.6e-24 85.6 0.6 1.8e-24 85.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.20 EMC96080.1 - 1.2e-18 67.0 15.4 1.2e-18 67.0 15.4 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EMC96080.1 - 2.6e-08 33.5 0.2 1.9e-07 30.8 0.1 2.3 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-H2C2_2 PF13465.6 EMC96080.1 - 0.73 10.4 4.5 28 5.4 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double domain CAP_N PF01213.19 EMC96080.1 - 7.1 6.0 5.4 3.1 7.2 2.5 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Med4 PF10018.9 EMC96082.1 - 0.19 11.4 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 FmdA_AmdA PF03069.15 EMC96083.1 - 1.8e-178 593.1 0.0 2.1e-178 592.9 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Mg_trans_NIPA PF05653.14 EMC96084.1 - 1e-90 303.9 26.3 1.3e-90 303.5 26.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EMC96084.1 - 3.6e-06 27.2 5.7 3.6e-06 27.2 5.7 3.2 3 0 0 3 3 3 3 EamA-like transporter family DUF5362 PF17319.2 EMC96084.1 - 0.093 12.6 0.3 0.093 12.6 0.3 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5362) DUF805 PF05656.14 EMC96084.1 - 0.11 12.9 11.4 2 8.9 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) COG4 PF08318.12 EMC96085.1 - 2.6e-125 418.0 0.0 3.5e-125 417.6 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein UPF0052 PF01933.18 EMC96085.1 - 0.0096 15.2 0.2 0.023 13.9 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0052 DUF3806 PF12713.7 EMC96085.1 - 0.13 12.0 0.1 35 4.2 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3806) HATPase_c PF02518.26 EMC96086.1 - 6.5e-26 91.0 0.3 1.3e-25 90.1 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 EMC96086.1 - 1.2e-19 70.4 1.4 3.7e-11 43.1 0.3 3.8 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 EMC96086.1 - 1.5e-17 63.4 0.1 4.7e-17 61.8 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EMC96086.1 - 1.9e-17 63.4 0.1 6e-17 61.8 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS PF00989.25 EMC96086.1 - 2.3e-13 50.1 0.0 6.2e-07 29.4 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 EMC96086.1 - 4.1e-13 49.5 3.0 1.1e-09 38.5 0.0 4.5 5 0 0 5 5 5 2 PAS fold PAS_9 PF13426.7 EMC96086.1 - 3.4e-10 40.1 0.0 0.0001 22.5 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_8 PF13188.7 EMC96086.1 - 1.3e-05 25.1 0.0 0.0073 16.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain Cactin_mid PF10312.9 EMC96086.1 - 0.15 11.8 1.6 1.7 8.3 0.8 2.5 2 0 0 2 2 2 0 Conserved mid region of cactin Cutinase PF01083.22 EMC96088.1 - 7.5e-21 74.9 1.0 8.6e-21 74.7 1.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EMC96088.1 - 0.031 13.8 0.1 0.043 13.4 0.1 1.4 1 0 0 1 1 1 0 PE-PPE domain CH PF00307.31 EMC96089.1 - 0.011 15.9 0.0 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 Calponin homology (CH) domain AOX PF01786.17 EMC96090.1 - 4.6e-97 323.8 0.8 6.1e-97 323.4 0.8 1.2 1 0 0 1 1 1 1 Alternative oxidase Acylphosphatase PF00708.18 EMC96090.1 - 2e-23 82.6 0.3 4.4e-23 81.5 0.3 1.6 1 0 0 1 1 1 1 Acylphosphatase Sulphotransf PF09037.10 EMC96090.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Stf0 sulphotransferase Pkinase PF00069.25 EMC96091.1 - 4.8e-11 42.5 0.0 6.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC96091.1 - 5.9e-09 35.6 0.0 8.5e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMC96091.1 - 0.0043 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMC96091.1 - 0.052 12.9 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like p450 PF00067.22 EMC96093.1 - 3e-56 191.1 0.0 3.7e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 EMC96094.1 - 5e-76 250.7 2.2 1.6e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMC96094.1 - 0.00017 20.8 0.9 0.26 10.4 0.3 3.4 3 1 0 3 3 3 2 Gammaproteobacterial serine protease GAD-like PF08887.11 EMC96094.1 - 0.068 13.0 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 GAD-like domain CAML PF14963.6 EMC96095.1 - 3.8 7.6 15.9 0.034 14.3 4.5 2.2 2 1 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand ELFV_dehydrog PF00208.21 EMC96096.1 - 4.4e-66 223.1 0.0 9.3e-66 222.0 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EMC96096.1 - 2.8e-16 58.3 0.1 2.6e-11 41.9 0.1 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EMC96096.1 - 0.048 13.6 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CorA PF01544.18 EMC96098.1 - 1.5e-42 145.9 3.9 5.3e-21 75.2 0.5 2.6 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein Pkinase PF00069.25 EMC96099.1 - 3.1e-41 141.5 0.0 4.2e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC96099.1 - 2.8e-16 59.6 0.0 4.1e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC96099.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMC96099.1 - 0.00069 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EMC96099.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMC96099.1 - 0.002 18.1 0.2 0.0083 16.1 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family AdoMet_Synthase PF01941.19 EMC96100.1 - 0.088 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Acyltransferase PF01553.21 EMC96101.1 - 1.8e-26 92.4 0.0 3e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EMC96101.1 - 1.8e-12 47.2 0.1 4.1e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF1330 PF07045.11 EMC96102.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Hep_59 PF07052.11 EMC96103.1 - 0.0014 19.4 0.2 0.0033 18.2 0.2 1.7 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Elongin_A PF06881.11 EMC96104.1 - 1.4e-29 102.7 2.2 1.8e-29 102.4 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A MucB_RseB_C PF17188.4 EMC96104.1 - 0.096 12.9 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 MucB/RseB C-terminal domain TBCA PF02970.16 EMC96105.1 - 2.3e-25 88.7 5.6 3.6e-25 88.1 5.2 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor A DUF2570 PF10828.8 EMC96105.1 - 0.005 16.6 2.2 0.0069 16.2 2.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2570) FIVAR PF07554.13 EMC96105.1 - 0.0068 17.1 0.7 0.047 14.4 0.1 2.1 2 0 0 2 2 2 1 FIVAR domain Spc7 PF08317.11 EMC96105.1 - 0.051 12.5 7.6 0.031 13.2 1.0 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 EMC96105.1 - 0.063 11.9 3.8 0.068 11.8 3.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PhaP_Bmeg PF09602.10 EMC96105.1 - 0.077 12.9 3.1 0.19 11.6 3.1 1.6 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Alb1 PF09135.11 EMC96105.1 - 0.1 13.5 3.4 0.053 14.4 1.6 1.5 1 1 1 2 2 2 0 Alb1 DUF4972 PF16342.5 EMC96105.1 - 0.16 11.7 2.1 0.26 11.0 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) Tho2 PF11262.8 EMC96105.1 - 0.17 11.0 2.3 0.2 10.8 2.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spectrin PF00435.21 EMC96105.1 - 0.57 10.7 7.2 0.53 10.8 5.3 1.8 1 1 1 2 2 2 0 Spectrin repeat DUF4407 PF14362.6 EMC96105.1 - 0.64 9.3 5.7 0.78 9.0 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 EMC96105.1 - 1.2 7.0 3.3 1.3 6.9 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4315 PF14193.6 EMC96105.1 - 2.4 8.2 9.8 27 4.8 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) Atg14 PF10186.9 EMC96105.1 - 3.9 6.5 7.2 5.5 6.0 7.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MCM PF00493.23 EMC96106.1 - 1.9e-98 328.0 0.0 2.8e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMC96106.1 - 5.2e-39 133.0 1.3 1e-38 132.0 1.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EMC96106.1 - 1.2e-28 99.4 3.0 2.6e-28 98.3 3.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMC96106.1 - 9e-13 48.7 0.3 1e-11 45.3 0.0 2.6 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMC96106.1 - 1.4e-05 24.6 0.0 0.0003 20.2 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EMC96106.1 - 5.6e-05 23.1 0.0 0.00023 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EMC96106.1 - 0.0013 18.6 0.0 0.0042 16.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Oberon_cc PF16312.5 EMC96106.1 - 0.073 13.0 3.6 0.17 11.8 3.6 1.6 1 0 0 1 1 1 0 Coiled-coil region of Oberon Sigma54_activat PF00158.26 EMC96106.1 - 0.13 12.0 0.1 3.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF4288 PF14119.6 EMC96106.1 - 3 8.3 4.0 2.2 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) ubiquitin PF00240.23 EMC96107.1 - 1e-25 89.3 0.1 1.1e-25 89.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EMC96107.1 - 1.9e-14 53.2 0.1 2.1e-14 53.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMC96107.1 - 0.00069 20.0 0.1 0.0018 18.7 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EMC96107.1 - 0.00071 19.4 0.0 0.00088 19.2 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMC96107.1 - 0.1 12.7 0.1 0.28 11.3 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like AD PF09793.9 EMC96108.1 - 3.2e-30 104.1 0.2 4.9e-30 103.5 0.2 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 EMC96108.1 - 0.027 14.0 0.0 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 Gemin6 protein Melibiase_2 PF16499.5 EMC96109.1 - 8.1e-40 136.8 1.0 1.2e-39 136.2 1.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EMC96109.1 - 2.5e-13 49.9 0.4 6.2e-13 48.6 0.4 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain ODR4-like PF14778.6 EMC96112.1 - 0.14 11.1 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Olfactory receptor 4-like Nab1 PF04902.12 EMC96114.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Conserved region in Nab1 Ank_5 PF13857.6 EMC96115.1 - 4.2e-05 23.8 0.1 0.92 9.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TPR_12 PF13424.6 EMC96115.1 - 5.8e-05 23.3 2.4 0.027 14.8 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Ank_3 PF13606.6 EMC96115.1 - 9.7e-05 22.5 0.2 0.64 10.8 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EMC96115.1 - 0.00073 20.1 0.0 1.8 9.2 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Helo_like_N PF17111.5 EMC96115.1 - 0.0031 16.9 0.2 0.0086 15.5 0.2 1.7 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TPR_2 PF07719.17 EMC96115.1 - 0.0045 17.0 0.8 11 6.4 0.8 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Ank PF00023.30 EMC96115.1 - 0.0072 16.7 0.6 31 5.2 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat TPR_19 PF14559.6 EMC96115.1 - 0.013 16.0 0.8 1.3 9.6 0.0 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat SesA PF17107.5 EMC96115.1 - 0.022 14.9 0.2 0.09 13.0 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_8 PF13181.6 EMC96115.1 - 0.037 14.2 0.4 3.5 8.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat IML1 PF12257.8 EMC96115.1 - 0.057 12.5 0.2 0.11 11.6 0.2 1.4 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 DUF3671 PF12420.8 EMC96119.1 - 0.04 14.0 0.8 0.049 13.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function FemAB PF02388.16 EMC96121.1 - 0.016 14.1 0.7 0.023 13.6 0.7 1.2 1 0 0 1 1 1 0 FemAB family DivIC PF04977.15 EMC96121.1 - 0.018 14.8 4.3 0.031 14.0 4.3 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4201 PF13870.6 EMC96121.1 - 0.038 13.7 1.4 0.066 12.9 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) AAA_13 PF13166.6 EMC96121.1 - 0.063 11.9 1.3 0.087 11.5 1.3 1.1 1 0 0 1 1 1 0 AAA domain BST2 PF16716.5 EMC96121.1 - 0.067 13.8 2.7 0.13 12.9 2.7 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Cob_adeno_trans PF01923.18 EMC96121.1 - 0.067 13.3 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF5446 PF17522.2 EMC96121.1 - 1.1 9.4 4.3 0.42 10.8 1.3 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF5446) SIP PF04954.13 EMC96121.1 - 4 8.0 6.7 17 5.9 6.7 1.9 1 1 0 1 1 1 0 Siderophore-interacting protein Prenylcys_lyase PF07156.14 EMC96125.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 Prenylcysteine lyase Epimerase PF01370.21 EMC96128.1 - 2.6e-24 86.0 0.0 1.5e-23 83.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC96128.1 - 7.2e-15 55.2 0.2 4.4e-14 52.6 0.1 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EMC96128.1 - 4.5e-11 42.4 0.0 6.9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EMC96128.1 - 4.9e-10 39.0 0.0 2e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EMC96128.1 - 5.5e-08 32.1 0.0 2.5e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EMC96128.1 - 1.2e-07 31.2 0.0 5e-05 22.6 0.0 2.6 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMC96128.1 - 1.2e-06 28.5 0.0 2.5e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC96128.1 - 0.14 11.7 0.0 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family MMU163 PF17119.5 EMC96129.1 - 1.7e-88 296.0 6.1 5.8e-64 215.6 0.4 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis TauD PF02668.16 EMC96131.1 - 8.5e-45 153.6 0.1 1.1e-44 153.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EMC96132.1 - 3.8e-23 82.0 19.2 5e-23 81.6 19.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EMC96132.1 - 0.0008 19.1 1.2 0.0008 19.1 1.2 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 HAD_2 PF13419.6 EMC96133.1 - 0.045 13.8 0.0 0.38 10.8 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase MetW PF07021.12 EMC96134.1 - 0.028 14.0 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 EMC96134.1 - 0.03 14.2 0.0 0.04 13.7 0.0 1.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 EMC96134.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Proteasome PF00227.26 EMC96135.1 - 4.1e-54 183.0 0.1 5.7e-54 182.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMC96135.1 - 1.8e-12 46.7 0.0 3.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 EMC96136.1 - 5.9e-69 233.0 1.3 2.8e-68 230.8 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EMC96136.1 - 8.7e-63 212.6 0.9 1.7e-62 211.6 0.9 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal FPP PF05911.11 EMC96137.1 - 0.00071 17.9 10.1 0.0009 17.6 10.1 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Exonuc_VII_L PF02601.15 EMC96137.1 - 0.013 15.1 11.5 0.018 14.7 11.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tup_N PF08581.10 EMC96137.1 - 0.023 15.0 2.8 0.023 15.0 2.8 2.4 1 1 1 3 3 3 0 Tup N-terminal Spc7 PF08317.11 EMC96137.1 - 0.038 12.9 17.6 0.056 12.3 17.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Borrelia_P83 PF05262.11 EMC96137.1 - 0.072 11.6 16.3 0.086 11.3 16.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ADIP PF11559.8 EMC96137.1 - 0.11 12.6 25.6 0.59 10.2 3.4 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.11 EMC96137.1 - 0.54 10.5 15.5 0.15 12.3 1.8 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Golgin_A5 PF09787.9 EMC96137.1 - 0.78 9.2 26.6 1.8 8.0 26.6 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 ERM PF00769.19 EMC96137.1 - 0.95 9.2 35.3 5.1 6.8 12.3 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family APG6_N PF17675.1 EMC96137.1 - 1 9.9 31.6 1.5 9.3 15.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Macoilin PF09726.9 EMC96137.1 - 1.4 7.4 15.7 1.8 7.0 15.7 1.2 1 0 0 1 1 1 0 Macoilin family DUF4472 PF14739.6 EMC96137.1 - 2.2 9.1 22.5 5 7.9 12.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) HAUS6_N PF14661.6 EMC96137.1 - 2.6 7.5 12.5 4.1 6.9 12.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MRP-L46 PF11788.8 EMC96137.1 - 4.2 8.1 13.2 5.9 7.7 12.1 1.7 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 DUF874 PF05917.11 EMC96137.1 - 6.8 5.6 15.2 9.6 5.1 15.2 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) IFT20 PF14931.6 EMC96137.1 - 7 6.9 20.1 0.41 10.8 4.6 2.4 1 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 THOC7 PF05615.13 EMC96137.1 - 8.2 6.7 23.9 1.2e+02 2.9 23.9 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 Peptidase_S15 PF02129.18 EMC96137.1 - 8.2 5.9 7.0 21 4.6 6.9 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3450 PF11932.8 EMC96137.1 - 9.4 5.4 29.1 2.7 7.2 13.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4315 PF14193.6 EMC96138.1 - 0.013 15.5 3.2 0.035 14.1 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Zn_clus PF00172.18 EMC96138.1 - 0.016 15.3 15.6 0.016 15.3 15.6 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF743 PF05332.11 EMC96138.1 - 0.26 11.4 1.1 0.59 10.2 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF743) FtsL PF04999.13 EMC96138.1 - 0.5 10.4 3.9 1.5 8.9 1.2 2.5 2 0 0 2 2 2 0 Cell division protein FtsL TMF_TATA_bd PF12325.8 EMC96138.1 - 3.1 8.1 7.5 1.5 9.0 2.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 EMC96138.1 - 3.6 7.9 8.9 0.42 10.9 3.1 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spheroidin PF05541.12 EMC96138.1 - 6.3 4.5 4.7 8.9 4.0 4.7 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein EspB_PE PF18625.1 EMC96138.1 - 8.9 6.9 8.8 1.2 9.7 0.6 2.9 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain Amidase PF01425.21 EMC96140.1 - 5.3e-89 299.2 0.0 6.3e-89 299.0 0.0 1.0 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 EMC96141.1 - 1.9e-07 31.0 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase COX4 PF02936.14 EMC96142.1 - 2.3e-15 56.8 0.5 3.2e-15 56.3 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 EMC96142.1 - 0.0026 18.2 1.6 0.0039 17.6 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3106) DUF3112 PF11309.8 EMC96143.1 - 8.9e-07 28.6 0.0 8.9e-07 28.6 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) UPF0182 PF03699.13 EMC96143.1 - 0.87 7.6 7.6 0.044 11.9 1.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) Zn_clus PF00172.18 EMC96144.1 - 0.00033 20.7 9.4 0.00057 19.9 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5039 PF16442.5 EMC96145.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) INTAP PF16617.5 EMC96145.1 - 1.3 9.4 6.7 1.8 9.0 2.2 2.6 1 1 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region TauD PF02668.16 EMC96147.1 - 1.4e-33 116.8 0.3 1.9e-33 116.5 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hydrolase_4 PF12146.8 EMC96148.1 - 1.5e-19 70.2 0.0 2.7e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMC96148.1 - 3e-19 69.7 0.0 3.2e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC96148.1 - 1.4e-15 58.5 0.3 1.8e-15 58.2 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EMC96148.1 - 3.7e-09 37.0 0.0 1.6e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 EMC96148.1 - 2.4e-05 24.3 0.2 0.11 12.4 0.5 2.6 1 1 1 2 2 2 2 Serine hydrolase FSH1 PF03959.13 EMC96148.1 - 4.3e-05 23.3 0.1 0.00055 19.7 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 EMC96148.1 - 0.00018 21.3 0.0 0.073 12.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EMC96148.1 - 0.00072 19.4 0.1 0.33 10.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.13 EMC96148.1 - 0.0022 17.8 0.5 0.052 13.3 0.5 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_4 PF08386.10 EMC96148.1 - 0.0055 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 EMC96148.1 - 0.0085 15.8 0.1 0.02 14.5 0.1 1.7 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.14 EMC96148.1 - 0.013 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF1749 PF08538.10 EMC96148.1 - 0.043 12.9 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydro_lipase PF04083.16 EMC96148.1 - 0.044 13.4 0.1 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF1057 PF06342.12 EMC96148.1 - 0.046 12.8 0.1 0.13 11.3 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) LIDHydrolase PF10230.9 EMC96148.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 EMC96148.1 - 0.11 12.4 0.2 1.4 8.8 0.2 2.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cep3 PF16846.5 EMC96149.1 - 0.055 11.9 0.0 0.081 11.4 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Transp_cyt_pur PF02133.15 EMC96150.1 - 9.2e-83 278.4 36.7 1.2e-82 278.0 36.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 EMC96151.1 - 5e-32 111.1 0.0 9.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMC96151.1 - 6e-21 74.8 0.1 1.3e-20 73.8 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HOOK PF05622.12 EMC96153.1 - 2.9e-16 58.8 37.5 2.3e-12 45.9 0.0 3.0 1 1 2 3 3 3 3 HOOK protein THOC7 PF05615.13 EMC96153.1 - 0.0026 18.0 2.0 0.0026 18.0 2.0 3.6 2 1 1 3 3 2 2 Tho complex subunit 7 TFR_dimer PF04253.15 EMC96153.1 - 0.023 14.8 1.8 0.023 14.8 1.8 2.5 2 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain DUF3450 PF11932.8 EMC96153.1 - 0.045 13.1 0.6 0.045 13.1 0.6 3.9 1 1 2 4 4 3 0 Protein of unknown function (DUF3450) RNA_pol_Rpb2_45 PF10385.9 EMC96153.1 - 0.053 13.8 1.4 2.2 8.6 0.3 2.8 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain GAS PF13851.6 EMC96153.1 - 0.16 11.3 39.6 0.13 11.6 1.8 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EMC96153.1 - 0.19 11.5 38.3 0.2 11.5 0.5 3.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 EMC96153.1 - 0.31 11.4 10.0 2.8 8.4 0.2 4.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 EMC96153.1 - 0.57 10.4 23.7 4.8 7.4 0.5 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FPP PF05911.11 EMC96153.1 - 1.1 7.3 36.8 1.7 6.7 7.5 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil GIT_CC PF16559.5 EMC96153.1 - 2.4 8.1 18.6 1.2 9.1 0.5 5.1 3 1 2 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Phage_int_SAM_1 PF02899.17 EMC96153.1 - 3.1 8.1 8.8 0.47 10.8 0.8 3.3 1 1 2 4 4 4 0 Phage integrase, N-terminal SAM-like domain FAM76 PF16046.5 EMC96153.1 - 3.5 6.9 24.1 5.8 6.2 18.5 2.3 2 0 0 2 2 2 0 FAM76 protein DUF2937 PF11157.8 EMC96153.1 - 4 7.1 10.3 1.8 8.3 4.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) HOOK PF05622.12 EMC96154.1 - 0.066 11.4 0.1 0.066 11.4 0.1 1.0 1 0 0 1 1 1 0 HOOK protein Mito_carr PF00153.27 EMC96155.1 - 3.9e-50 167.7 5.3 2.5e-16 59.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF2157 PF09925.9 EMC96155.1 - 0.02 14.7 0.1 0.045 13.5 0.1 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Abp2 PF09441.10 EMC96156.1 - 9.7e-81 269.9 0.0 1.6e-80 269.2 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 ARID PF01388.21 EMC96156.1 - 0.079 13.6 0.0 0.23 12.2 0.0 1.8 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain HopA1 PF17914.1 EMC96157.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 HopA1 effector protein family TPT PF03151.16 EMC96158.1 - 1.4e-55 188.7 5.3 1.7e-55 188.4 5.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EMC96158.1 - 1.7e-08 34.7 22.7 6.2e-05 23.2 6.0 3.0 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EMC96158.1 - 1.2e-07 31.3 10.4 4.3e-07 29.4 10.4 1.8 1 1 0 1 1 1 1 UAA transporter family Peptidase_S9 PF00326.21 EMC96159.1 - 8.6e-08 31.9 0.2 1.5e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EMC96159.1 - 0.0017 18.1 0.3 0.0037 17.0 0.3 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EMC96159.1 - 0.04 13.7 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase RHD3 PF05879.12 EMC96160.1 - 0 1032.5 0.0 0 1032.2 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EMC96160.1 - 9.4e-08 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EMC96160.1 - 1.8e-05 24.9 0.7 2.9e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EMC96160.1 - 0.00025 21.1 0.0 0.00054 20.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2461 PF09365.10 EMC96160.1 - 0.026 14.5 0.1 0.26 11.2 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) AAA_23 PF13476.6 EMC96160.1 - 0.041 14.4 2.5 4.1 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EMC96160.1 - 0.048 13.9 0.8 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EMC96160.1 - 0.055 12.7 0.1 0.097 11.9 0.1 1.3 1 0 0 1 1 1 0 Septin Phosphodiest PF01663.22 EMC96161.1 - 9.2e-13 48.5 0.1 1.6e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMC96161.1 - 6.7e-05 22.4 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EMC96161.1 - 0.0012 18.3 0.1 0.002 17.5 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Cohesin_load PF10345.9 EMC96162.1 - 1.9e-110 370.1 4.6 2.3e-110 369.9 4.6 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_7 PF13176.6 EMC96163.1 - 0.41 10.8 2.2 6.5 7.0 1.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ExsD PF16806.5 EMC96163.1 - 0.49 10.3 8.7 8.5 6.2 6.3 2.7 2 1 0 2 2 2 0 Antiactivator protein ExsD TMCO5 PF14992.6 EMC96163.1 - 3 7.3 9.6 5.1 6.6 9.6 1.4 1 0 0 1 1 1 0 TMCO5 family APG6_N PF17675.1 EMC96163.1 - 7.4 7.1 19.6 5.2 7.6 16.8 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region WXG100 PF06013.12 EMC96163.1 - 7.4 6.9 11.2 2.1 8.6 1.1 3.2 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Vps55 PF04133.14 EMC96164.1 - 8.6e-44 148.2 6.6 9.8e-44 148.1 6.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 EMC96164.1 - 0.74 9.2 0.0 0.74 9.2 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) DUF2614 PF11023.8 EMC96164.1 - 8.2 6.6 7.1 1.2 9.3 0.7 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain Proteasome PF00227.26 EMC96165.1 - 6.9e-43 146.3 0.0 9e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMC96165.1 - 2.8e-12 46.1 0.3 4.8e-12 45.3 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ATP-synt_ab PF00006.25 EMC96166.1 - 2.7e-61 206.9 0.0 4.4e-61 206.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EMC96166.1 - 7.3e-23 80.9 1.3 3.3e-22 78.8 1.1 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 EMC96166.1 - 0.012 14.8 0.6 0.081 12.1 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 EMC96166.1 - 0.018 14.4 0.2 0.034 13.5 0.2 1.4 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 EMC96166.1 - 0.019 14.8 0.7 0.04 13.8 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 EMC96166.1 - 0.02 15.3 0.1 1 9.8 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EMC96166.1 - 0.047 13.6 0.3 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain T3SS_ATPase_C PF18269.1 EMC96166.1 - 0.047 13.5 1.0 0.3 11.0 1.0 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 EMC96166.1 - 0.064 13.6 0.7 0.48 10.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EMC96166.1 - 0.086 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EMC96166.1 - 0.14 12.5 0.7 0.4 11.1 0.2 2.1 2 1 0 2 2 2 0 AAA ATPase domain DUF1858 PF08984.11 EMC96166.1 - 0.16 12.1 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) Aminotran_3 PF00202.21 EMC96167.1 - 6.2e-121 403.9 0.0 7e-121 403.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EMC96167.1 - 0.05 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3402 PF11882.8 EMC96168.1 - 1.1e-165 552.3 0.0 1.6e-165 551.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EMC96168.1 - 2.7e-87 292.6 0.0 4.1e-87 292.0 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Abhydrolase_1 PF00561.20 EMC96169.1 - 2.6e-09 37.1 0.0 2.1e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC96169.1 - 2.9e-06 26.8 0.0 1.2e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 VirJ PF06057.11 EMC96169.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipoprotein_20 PF13942.6 EMC96169.1 - 0.17 11.8 0.1 0.26 11.2 0.1 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Cutinase PF01083.22 EMC96169.1 - 0.18 11.7 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase D123 PF07065.14 EMC96171.1 - 2.9e-113 378.1 0.1 3.4e-113 377.9 0.1 1.0 1 0 0 1 1 1 1 D123 NAD_binding_10 PF13460.6 EMC96172.1 - 2.9e-09 37.1 0.0 4.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC96172.1 - 1.2e-06 28.2 0.0 2e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMC96172.1 - 0.00066 19.2 0.0 0.0026 17.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMC96172.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96172.1 - 0.034 13.7 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase CF222 PF15661.5 EMC96172.1 - 0.093 11.6 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 C6orf222, uncharacterised family KR PF08659.10 EMC96172.1 - 0.14 12.0 0.0 0.33 10.9 0.0 1.6 1 1 0 1 1 1 0 KR domain Polysacc_deac_1 PF01522.21 EMC96174.1 - 2e-15 56.8 0.5 2.2e-14 53.4 0.5 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMC96174.1 - 0.053 13.2 0.4 0.89 9.2 0.4 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) 6PF2K PF01591.18 EMC96175.1 - 5.5e-75 251.5 0.0 7.8e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EMC96175.1 - 2.8e-26 92.4 0.0 2.9e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EMC96175.1 - 1.5e-06 28.4 0.0 4.7e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 EMC96175.1 - 0.023 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EMC96175.1 - 0.065 12.5 0.0 0.93 8.7 0.0 2.1 1 1 0 1 1 1 0 Zeta toxin SEC-C PF02810.15 EMC96178.1 - 4.2 7.4 6.7 0.24 11.4 1.2 1.8 2 0 0 2 2 2 0 SEC-C motif DUF3381 PF11861.8 EMC96179.1 - 0.11 12.3 0.3 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FYDLN_acid PF09538.10 EMC96180.1 - 0.011 16.4 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Acyl-CoA_dh_1 PF00441.24 EMC96181.1 - 6.1e-39 133.6 0.8 8.7e-39 133.1 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMC96181.1 - 1.3e-21 76.6 0.0 3e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMC96181.1 - 4.8e-13 49.5 0.1 8.2e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMC96181.1 - 1.1e-07 32.5 0.1 7.7e-07 29.8 0.1 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Mst1_SARAH PF11629.8 EMC96181.1 - 0.087 12.9 1.1 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DEAD_2 PF06733.15 EMC96181.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 DEAD_2 EthD PF07110.11 EMC96183.1 - 4.1e-20 72.7 0.2 5e-20 72.4 0.2 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EMC96183.1 - 7.9e-06 26.3 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase RRP36 PF06102.12 EMC96184.1 - 2.5e-48 164.2 25.7 2.5e-48 164.2 25.7 2.2 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 MIT PF04212.18 EMC96184.1 - 0.088 12.9 0.3 0.088 12.9 0.3 3.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Questin_oxidase PF14027.6 EMC96184.1 - 0.16 11.5 4.2 0.19 11.2 4.2 1.4 1 0 0 1 1 1 0 Questin oxidase-like RB_A PF01858.17 EMC96184.1 - 3.8 7.3 5.8 0.54 10.1 1.5 1.8 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain DUF4404 PF14357.6 EMC96184.1 - 4.1 8.1 10.7 8.7 7.1 3.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CDC27 PF09507.10 EMC96184.1 - 6.4 6.0 39.1 1.5 8.1 16.8 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 HIG_1_N PF04588.13 EMC96185.1 - 1e-05 25.6 0.4 1e-05 25.6 0.4 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF3169 PF11368.8 EMC96185.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) Serglycin PF04360.12 EMC96186.1 - 0.041 13.8 0.8 0.041 13.8 0.8 2.2 2 0 0 2 2 2 0 Serglycin Vps51 PF08700.11 EMC96187.1 - 4.1e-11 42.8 0.0 5.1e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 DUF4455 PF14643.6 EMC96187.1 - 0.04 12.6 0.1 0.96 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) COG2 PF06148.11 EMC96187.1 - 0.069 13.2 5.4 3.1 7.9 0.0 4.5 5 0 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 PrmC_N PF17827.1 EMC96188.1 - 1.5e-05 25.5 0.5 0.00013 22.5 0.5 2.3 1 1 0 1 1 1 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 EMC96188.1 - 2.4e-05 24.2 0.0 6e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 EMC96188.1 - 0.00055 19.4 0.0 0.0034 16.8 0.0 2.1 2 1 1 3 3 3 1 RNA methyltransferase N6_Mtase PF02384.16 EMC96188.1 - 0.00063 19.1 0.0 0.0024 17.2 0.0 1.7 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.6 EMC96188.1 - 0.00081 20.0 0.0 0.0033 18.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EMC96188.1 - 0.00087 18.9 0.0 0.077 12.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.18 EMC96188.1 - 0.061 13.0 0.0 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 XPC-binding PF09280.11 EMC96189.1 - 1.5e-24 85.4 17.6 2.7e-24 84.7 17.6 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EMC96189.1 - 4.8e-23 80.7 6.0 1.7e-12 47.0 0.8 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EMC96189.1 - 7.5e-21 73.7 0.1 1.2e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EMC96189.1 - 3.7e-08 33.1 0.2 6.9e-08 32.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMC96189.1 - 0.019 15.4 0.1 0.054 14.0 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain MCM_N PF14551.6 EMC96189.1 - 0.019 15.5 0.2 0.04 14.5 0.2 1.5 1 0 0 1 1 1 0 MCM N-terminal domain Rad60-SLD_2 PF13881.6 EMC96189.1 - 0.026 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EMC96189.1 - 0.043 14.2 0.1 0.081 13.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_3 PF09288.10 EMC96189.1 - 0.045 13.6 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF2407 PF10302.9 EMC96189.1 - 0.063 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF1421 PF07223.11 EMC96189.1 - 0.11 12.4 0.0 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) DUF3135 PF11333.8 EMC96189.1 - 0.12 12.7 4.2 1.3 9.3 3.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3135) CCDC53 PF10152.9 EMC96189.1 - 3.9 7.9 14.0 0.45 10.9 1.6 2.6 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF3391 PF11871.8 EMC96189.1 - 6.5 7.3 10.2 2.4 8.7 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) TMEM51 PF15345.6 EMC96192.1 - 0.015 15.1 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Mcp5_PH PF12814.7 EMC96192.1 - 0.02 15.0 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology CD34_antigen PF06365.12 EMC96192.1 - 0.026 14.1 0.3 0.034 13.7 0.3 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 EMC96192.1 - 0.031 15.2 0.1 0.052 14.4 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3328 PF11807.8 EMC96192.1 - 0.041 13.7 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) HemY_N PF07219.13 EMC96192.1 - 0.064 13.5 0.8 0.1 12.8 0.8 1.3 1 0 0 1 1 1 0 HemY protein N-terminus TMEM154 PF15102.6 EMC96192.1 - 0.085 12.8 0.2 0.17 11.8 0.1 1.4 1 1 0 1 1 1 0 TMEM154 protein family Tmemb_9 PF05434.11 EMC96192.1 - 0.093 12.6 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 TMEM9 DUF2921 PF11145.8 EMC96192.1 - 0.1 10.4 0.0 0.11 10.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) DUF4381 PF14316.6 EMC96192.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) V_ATPase_I PF01496.19 EMC96192.1 - 0.13 10.1 0.0 0.15 9.9 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 EMC96192.1 - 0.18 12.8 0.1 0.28 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4083 PF13314.6 EMC96192.1 - 2.8 7.9 6.2 0.38 10.7 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Gram_pos_anchor PF00746.21 EMC96192.1 - 5.5 7.0 5.6 13 5.8 2.9 2.5 2 1 0 2 2 2 0 LPXTG cell wall anchor motif Myb_DNA-binding PF00249.31 EMC96193.1 - 1e-14 54.4 6.0 8.9e-12 45.0 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC96193.1 - 1.1e-08 35.2 7.4 2.1e-05 24.7 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.25 EMC96195.1 - 1.3e-25 89.1 0.2 1.9e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EMC96195.1 - 3.8e-20 72.1 0.0 5.6e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EMC96195.1 - 0.00042 20.0 0.0 0.00091 18.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Gemini_AL2 PF01440.16 EMC96195.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Geminivirus AL2 protein Mif2_N PF15624.6 EMC96196.1 - 9e-31 107.4 1.1 9e-31 107.4 1.1 3.8 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 EMC96196.1 - 2.5e-25 88.5 0.2 4.2e-25 87.8 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EMC96196.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Cupin domain RNase_HII PF01351.18 EMC96198.1 - 6e-48 163.3 0.0 7.4e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Band_7 PF01145.25 EMC96198.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 SPFH domain / Band 7 family Rap_GAP PF02145.15 EMC96199.1 - 4.4e-41 140.5 0.0 7.9e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EMC96199.1 - 1.5e-27 96.7 1.3 4.3e-24 85.3 0.1 2.4 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.8 EMC96199.1 - 1.8e-18 66.7 2.2 2e-18 66.6 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) RIX1 PF08167.12 EMC96199.1 - 0.026 14.3 0.3 0.11 12.3 0.0 2.2 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis PORR PF11955.8 EMC96199.1 - 0.058 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Plant organelle RNA recognition domain TRAPPC9-Trs120 PF08626.11 EMC96201.1 - 2.3e-151 505.6 0.0 4.3e-143 478.2 0.0 3.7 3 2 0 3 3 3 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ANAPC5 PF12862.7 EMC96201.1 - 0.076 13.1 0.0 6.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 SpoVIF PF14069.6 EMC96201.1 - 0.088 12.6 0.0 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Stage VI sporulation protein F WW PF00397.26 EMC96202.1 - 4e-10 39.6 4.6 3.6e-06 26.9 4.6 2.9 2 0 0 2 2 2 2 WW domain TauD PF02668.16 EMC96203.1 - 1.9e-28 100.0 1.9 6.3e-28 98.3 1.9 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.6 EMC96204.1 - 7.8e-20 71.8 0.0 1.8e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMC96204.1 - 1.5e-15 57.5 0.0 4.3e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_61 PF03443.14 EMC96205.1 - 2.9e-66 223.3 0.0 5.6e-66 222.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NmrA PF05368.13 EMC96207.1 - 7.7e-26 91.1 0.0 9.9e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC96207.1 - 3.2e-19 69.5 0.0 6e-19 68.7 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMC96207.1 - 1.3e-05 25.4 0.0 3e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EMC96207.1 - 0.0002 20.9 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EMC96207.1 - 0.03 14.8 0.1 6.6 7.2 0.0 3.0 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EMC96207.1 - 0.041 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NMT PF01233.19 EMC96207.1 - 0.16 11.8 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain FMN_dh PF01070.18 EMC96208.1 - 1.5e-106 356.4 0.0 1.8e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EMC96208.1 - 2e-16 59.9 0.0 3.8e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EMC96208.1 - 7.7e-07 28.6 0.0 1.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EMC96208.1 - 8.2e-05 21.8 0.1 0.0014 17.7 0.0 2.5 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMC96208.1 - 0.019 14.4 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ATP11 PF06644.11 EMC96208.1 - 0.026 14.3 0.1 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 ATP11 protein NUDIX PF00293.28 EMC96209.1 - 3.2e-12 46.6 0.1 7e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain VTC PF09359.10 EMC96210.1 - 3e-87 292.5 0.4 5e-87 291.8 0.4 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EMC96210.1 - 1.1e-11 45.0 5.1 1.1e-11 45.0 5.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EMC96210.1 - 5.4e-05 23.3 2.0 5.4e-05 23.3 2.0 4.2 3 1 1 4 4 4 2 SPX domain Sigma70_ner PF04546.13 EMC96210.1 - 0.012 15.5 0.1 0.012 15.5 0.1 3.0 4 1 0 4 4 4 0 Sigma-70, non-essential region Ribosomal_L28e PF01778.17 EMC96213.1 - 1e-35 122.9 1.3 1.7e-35 122.2 1.3 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 EMC96213.1 - 4.4e-26 91.4 15.1 4.4e-26 91.4 15.1 2.6 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 EMC96213.1 - 8.1e-05 22.1 17.0 0.00011 21.7 17.0 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 EMC96213.1 - 0.9 7.7 26.0 1.2 7.2 26.0 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 EMC96213.1 - 1.5 8.4 12.0 3 7.5 12.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RNA12 PF10443.9 EMC96215.1 - 7.5e-165 549.0 0.0 9.5e-165 548.6 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EMC96215.1 - 1.3e-06 28.6 0.0 0.00015 21.8 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea RRM_1 PF00076.22 EMC96215.1 - 9.1e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 EMC96215.1 - 0.0018 18.7 0.2 0.013 15.8 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2487 PF10673.9 EMC96215.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) ScsC_N PF18312.1 EMC96215.1 - 2.3 8.1 6.2 2.5 8.0 0.0 3.5 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain Glyco_hydro_31 PF01055.26 EMC96216.1 - 1.1e-132 443.4 7.3 1.5e-132 443.0 7.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EMC96216.1 - 7.6e-29 100.3 0.0 1.4e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DUF4246 PF14033.6 EMC96217.1 - 5.4e-155 516.9 0.0 6.3e-155 516.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) PUF PF00806.19 EMC96218.1 - 1.7e-37 125.0 1.1 5.9e-07 28.8 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.11 EMC96218.1 - 0.0095 16.6 0.0 0.027 15.2 0.0 1.7 1 0 0 1 1 1 1 Regulator of ribonuclease activity B Aldo_ket_red PF00248.21 EMC96219.1 - 4.9e-41 140.8 0.1 1.1e-39 136.4 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Cauli_VI PF01693.16 EMC96220.1 - 1.1e-37 128.0 0.9 2.7e-19 69.2 0.1 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 EMC96220.1 - 6.6e-30 104.2 1.7 3.4e-23 82.4 0.0 2.4 2 0 0 2 2 2 2 RNase H DUF202 PF02656.15 EMC96221.1 - 0.0014 19.0 7.4 0.0072 16.7 7.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF202) SmpB PF01668.18 EMC96221.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 SmpB protein P_C10 PF14974.6 EMC96222.1 - 0.16 12.1 0.4 3.2 7.9 0.0 2.7 3 0 0 3 3 3 0 Protein C10 Abhydrolase_6 PF12697.7 EMC96223.1 - 2e-12 48.2 6.8 1e-11 45.9 6.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC96223.1 - 4.1e-05 23.0 0.1 9.1e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMC96223.1 - 0.00041 20.1 0.1 0.0058 16.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 EMC96223.1 - 0.18 10.5 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family ADH_zinc_N PF00107.26 EMC96224.1 - 8.1e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC96224.1 - 0.019 16.0 0.0 0.055 14.5 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Catalase PF00199.19 EMC96225.1 - 6.3e-06 25.5 0.1 3.9e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Catalase Glyco_hydro_76 PF03663.14 EMC96226.1 - 6.5e-148 493.1 25.4 7.5e-148 492.9 25.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EMC96226.1 - 0.0021 17.2 11.3 0.088 11.9 0.3 2.7 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Meth_synt_2 PF01717.18 EMC96227.1 - 1.4e-08 34.4 0.0 4e-05 23.1 0.0 2.7 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Phage_Orf51 PF06194.11 EMC96227.1 - 0.069 13.2 0.2 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 Mak10 PF04112.13 EMC96229.1 - 4.1e-59 198.8 0.1 1.1e-58 197.4 0.0 1.8 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase CbiX PF01903.17 EMC96229.1 - 0.02 15.2 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 CbiX ATP-synt_Eps PF04627.13 EMC96230.1 - 2.6e-24 85.0 1.4 3.8e-24 84.4 1.4 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF5528 PF17666.1 EMC96232.1 - 0.033 14.2 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5528) GRIM-19 PF06212.12 EMC96232.1 - 0.13 12.3 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 GRIM-19 protein POC1 PF10450.9 EMC96233.1 - 0.18 10.8 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 POC1 chaperone UPF0061 PF02696.14 EMC96238.1 - 3.1e-128 428.5 0.0 3.9e-128 428.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF4391 PF14335.6 EMC96238.1 - 0.17 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF2142 PF09913.9 EMC96239.1 - 0.025 13.4 0.1 0.041 12.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) BTB PF00651.31 EMC96241.1 - 1.8e-10 41.1 0.0 4.9e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Myosin_tail_1 PF01576.19 EMC96241.1 - 0.0001 20.3 3.7 0.00013 19.9 3.7 1.1 1 0 0 1 1 1 1 Myosin tail WEMBL PF05701.11 EMC96241.1 - 0.0025 16.6 12.9 0.0033 16.2 12.9 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF3584 PF12128.8 EMC96241.1 - 0.0073 13.9 6.5 0.0096 13.5 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fez1 PF06818.15 EMC96241.1 - 0.012 16.0 5.4 0.02 15.3 5.4 1.3 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 EMC96241.1 - 0.014 14.3 7.6 0.022 13.7 7.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 EMC96241.1 - 0.025 15.2 5.0 0.055 14.1 2.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Lebercilin PF15619.6 EMC96241.1 - 0.049 13.3 7.3 0.081 12.6 7.3 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TraG_N PF07916.11 EMC96241.1 - 0.07 12.0 0.8 0.091 11.6 0.8 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF4407 PF14362.6 EMC96241.1 - 0.097 12.0 9.6 0.14 11.5 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 EMC96241.1 - 0.12 11.8 5.0 0.19 11.2 5.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 PIN_8 PF18476.1 EMC96241.1 - 0.13 12.1 6.4 0.14 12.0 5.3 1.5 2 0 0 2 2 2 0 PIN like domain TPR_MLP1_2 PF07926.12 EMC96241.1 - 0.19 11.8 16.3 0.052 13.6 5.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Ku_C PF03730.14 EMC96241.1 - 0.21 12.3 2.9 0.64 10.7 3.0 1.8 2 0 0 2 2 1 0 Ku70/Ku80 C-terminal arm HAUS-augmin3 PF14932.6 EMC96241.1 - 0.21 11.2 10.0 2.1 7.9 10.0 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.19 EMC96241.1 - 0.21 9.5 1.5 0.27 9.1 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LRS4 PF10422.9 EMC96241.1 - 0.28 10.7 6.7 0.43 10.1 6.7 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 KLRAQ PF10205.9 EMC96241.1 - 0.3 11.3 5.7 0.61 10.4 5.7 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein BST2 PF16716.5 EMC96241.1 - 1.1 9.8 11.7 2.6 8.7 7.9 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF724 PF05266.14 EMC96241.1 - 1.3 8.8 7.4 2.2 8.1 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 EMC96241.1 - 2.1 8.4 14.1 0.46 10.6 1.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 EMC96241.1 - 4.2 7.8 11.7 27 5.2 8.8 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Uso1_p115_C PF04871.13 EMC96241.1 - 4.4 7.7 17.1 12 6.2 14.9 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_DNA_bd PF12329.8 EMC96241.1 - 5.4 7.1 10.9 17 5.5 5.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 EMC96241.1 - 8 5.6 6.4 11 5.1 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein AATF-Che1 PF13339.6 EMC96241.1 - 9.1 7.0 11.1 66 4.2 11.1 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor ECH_1 PF00378.20 EMC96242.1 - 2.4e-26 92.6 0.1 3.3e-26 92.1 0.1 1.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMC96242.1 - 2.3e-15 57.0 0.0 2.6e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pet100 PF09803.9 EMC96243.1 - 1.7e-22 79.7 0.2 1.9e-22 79.5 0.2 1.0 1 0 0 1 1 1 1 Pet100 DUF5621 PF18532.1 EMC96243.1 - 0.042 13.8 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) EF-1_beta_acid PF10587.9 EMC96243.1 - 2 8.9 6.2 2.7 8.5 6.2 1.2 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Polysacc_deac_1 PF01522.21 EMC96244.1 - 2.2e-14 53.4 0.0 3.6e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Tropomyosin_1 PF12718.7 EMC96246.1 - 0.0088 16.2 0.5 0.0088 16.2 0.5 1.5 2 0 0 2 2 2 1 Tropomyosin like IBR PF01485.21 EMC96247.1 - 3.8e-19 68.7 31.6 2.4e-13 50.1 1.0 3.8 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 EMC96247.1 - 2.7e-14 53.5 0.0 4.5e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EMC96247.1 - 4.6e-05 23.7 6.5 4.6e-05 23.7 6.5 4.0 3 1 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 EMC96247.1 - 0.0001 22.2 5.2 0.0001 22.2 5.2 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMC96247.1 - 0.00019 21.3 7.0 0.00019 21.3 7.0 3.4 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 EMC96247.1 - 0.00079 19.1 4.3 0.00079 19.1 4.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EMC96247.1 - 0.0053 16.6 7.5 0.0053 16.6 7.5 4.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC96247.1 - 0.017 15.0 5.1 0.017 15.0 5.1 4.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMC96247.1 - 0.027 14.6 2.1 0.027 14.6 2.1 4.1 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING MHC_I_C PF06623.11 EMC96247.1 - 0.18 11.8 1.1 0.35 10.8 1.1 1.5 1 0 0 1 1 1 0 MHC_I C-terminus PAP2 PF01569.21 EMC96248.1 - 1.7e-11 44.1 2.9 1.7e-11 44.1 2.9 1.8 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EMC96248.1 - 0.017 15.3 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 0 Divergent PAP2 family DUF4149 PF13664.6 EMC96248.1 - 0.96 9.8 4.6 0.93 9.8 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) PAC3 PF10178.9 EMC96249.1 - 3.1e-05 24.0 0.0 5.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 ADH_N PF08240.12 EMC96252.1 - 4.5e-25 87.7 0.9 7.6e-25 86.9 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC96252.1 - 1.1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMC96252.1 - 4.2e-06 26.4 0.4 0.00027 20.5 0.2 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMC96252.1 - 0.0045 18.0 0.0 0.0079 17.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FA_desaturase PF00487.24 EMC96253.1 - 7.4e-22 78.4 21.7 2.1e-21 76.9 21.7 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EMC96253.1 - 1e-07 32.2 0.0 2.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Meth_synt_2 PF01717.18 EMC96254.1 - 5.1e-19 68.7 0.0 2.2e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EMC96254.1 - 5.5e-05 22.8 0.0 0.071 12.6 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain ACD PF16671.5 EMC96254.1 - 0.12 10.7 0.0 0.19 10.0 0.0 1.3 1 0 0 1 1 1 0 Actin cross-linking domain Uroplakin_II PF07353.12 EMC96255.1 - 0.018 14.6 1.3 0.024 14.1 1.3 1.1 1 0 0 1 1 1 0 Uroplakin II DUF3295 PF11702.8 EMC96256.1 - 0.011 15.2 0.3 0.012 15.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TGT PF01702.18 EMC96257.1 - 1.8 7.6 5.1 0.87 8.7 3.0 1.4 1 1 0 1 1 1 0 Queuine tRNA-ribosyltransferase Arb2 PF09757.9 EMC96258.1 - 2.6e-85 285.7 0.3 3.3e-85 285.3 0.3 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EMC96258.1 - 2.5e-81 273.5 0.1 5.8e-81 272.3 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain CT_A_B PF02626.15 EMC96259.1 - 4.9e-79 265.7 0.0 7.3e-79 265.1 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 EMC96259.1 - 2.3e-58 197.2 0.0 3.9e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EMC96259.1 - 8.9e-36 122.8 0.0 2e-35 121.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EMC96259.1 - 7.4e-30 103.2 0.0 1.5e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CT_C_D PF02682.16 EMC96259.1 - 1.3e-29 103.4 0.0 2.9e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_lipoyl PF00364.22 EMC96259.1 - 5e-13 48.7 1.0 1.8e-12 46.9 1.0 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EMC96259.1 - 1.5e-08 34.4 0.0 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EMC96259.1 - 0.00079 19.2 1.7 0.86 9.5 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EMC96259.1 - 0.0018 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EMC96259.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 1 1 0 1 1 1 0 RimK-like ATP-grasp domain tRNA_bind_4 PF18490.1 EMC96259.1 - 0.057 13.2 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 tRNA-binding domain ATP-grasp_5 PF13549.6 EMC96259.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain LamB_YcsF PF03746.16 EMC96260.1 - 3.9e-74 249.3 0.0 4.4e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family GFO_IDH_MocA PF01408.22 EMC96261.1 - 8.8e-19 68.5 0.0 1.4e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMC96261.1 - 1.9e-10 40.8 0.2 6.9e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EMC96261.1 - 8e-07 29.7 0.0 1.4e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EMC96261.1 - 0.0028 18.1 0.0 0.0096 16.4 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF2012 PF09430.10 EMC96262.1 - 2.7e-25 88.9 0.0 3.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Mst1_SARAH PF11629.8 EMC96262.1 - 0.061 13.4 0.3 0.1 12.7 0.3 1.3 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 SOP4 PF17081.5 EMC96262.1 - 0.11 12.1 0.0 1.1 8.8 0.0 2.0 1 1 0 1 1 1 0 Suppressor of PMA 1-7 protein DUF445 PF04286.12 EMC96266.1 - 0.00064 19.6 16.9 0.00064 19.6 16.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF445) Sin3_corepress PF08295.12 EMC96266.1 - 0.051 13.6 0.5 0.15 12.1 0.5 1.8 1 0 0 1 1 1 0 Sin3 family co-repressor Ge1_WD40 PF16529.5 EMC96266.1 - 0.087 11.8 0.0 0.81 8.6 0.0 2.3 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PIN_12 PF16289.5 EMC96266.1 - 0.66 10.4 2.7 3.9 7.9 0.0 3.2 2 1 0 3 3 3 0 PIN domain DUF16 PF01519.16 EMC96266.1 - 5.1 7.7 16.7 0.45 11.0 8.8 3.3 3 1 0 3 3 3 0 Protein of unknown function DUF16 Cation_efflux PF01545.21 EMC96268.1 - 9.8e-26 90.7 3.8 1.2e-25 90.4 3.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMC96268.1 - 0.00023 21.2 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF2985 PF11204.8 EMC96269.1 - 1e-20 73.7 3.6 1.6e-20 73.0 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 EMC96269.1 - 0.012 15.7 0.1 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Sugar_tr PF00083.24 EMC96269.1 - 0.54 9.1 5.1 0.11 11.4 0.3 1.9 2 0 0 2 2 2 0 Sugar (and other) transporter Aldo_ket_red PF00248.21 EMC96270.1 - 1.7e-67 227.7 0.0 2e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SLATT_fungal PF18142.1 EMC96271.1 - 6.2e-31 106.9 0.0 9.7e-31 106.2 0.0 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain HD_5 PF13487.6 EMC96271.1 - 0.036 14.3 0.5 11 6.3 0.9 2.6 2 1 0 2 2 2 0 HD domain CARMIL_C PF16000.5 EMC96271.1 - 0.064 12.9 9.3 0.089 12.4 9.3 1.2 1 0 0 1 1 1 0 CARMIL C-terminus LIN37 PF15306.6 EMC96271.1 - 0.26 11.5 6.7 0.46 10.7 6.7 1.4 1 0 0 1 1 1 0 LIN37 TFIIA PF03153.13 EMC96271.1 - 1.7 8.5 10.5 2.3 8.1 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF346 PF03984.13 EMC96273.1 - 7.2e-17 60.9 23.2 0.00032 20.4 0.8 7.6 7 0 0 7 7 7 6 Repeat of unknown function (DUF346) Cyclin PF08613.11 EMC96274.1 - 4.6e-31 108.4 0.1 1.4e-30 106.8 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EMC96274.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.23 EMC96275.1 - 2.3e-10 40.2 5.6 0.035 14.1 0.0 7.8 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EMC96275.1 - 0.00041 20.4 9.0 1.8 9.0 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EMC96275.1 - 0.016 15.6 0.3 0.016 15.6 0.3 5.4 6 0 0 6 6 6 0 HEAT repeats V-ATPase_H_C PF11698.8 EMC96275.1 - 0.066 13.3 0.2 0.47 10.6 0.0 2.6 2 0 0 2 2 2 0 V-ATPase subunit H Ribosomal_S5_C PF03719.15 EMC96275.1 - 0.07 12.6 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Adaptin_N PF01602.20 EMC96275.1 - 0.1 11.1 0.2 0.36 9.3 0.2 1.9 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 EMC96275.1 - 1.7 9.2 15.9 14 6.3 0.4 5.8 6 1 0 6 6 6 0 HEAT-like repeat Ysc84 PF04366.12 EMC96276.1 - 1.5e-43 147.6 0.0 2.1e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator FAM110_C PF14160.6 EMC96276.1 - 0.063 14.3 0.0 0.12 13.4 0.0 1.5 1 0 0 1 1 1 0 Centrosome-associated C terminus dCMP_cyt_deam_1 PF00383.23 EMC96277.1 - 6.4e-07 29.2 0.2 2.2e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMC96277.1 - 7.4e-05 22.5 0.1 0.00074 19.3 0.1 2.1 2 0 0 2 2 2 1 MafB19-like deaminase ORC5_C PF14630.6 EMC96279.1 - 3.8e-73 246.5 0.0 5.2e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EMC96279.1 - 1.8e-12 47.9 0.1 7.5e-12 46.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RNA12 PF10443.9 EMC96279.1 - 0.022 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein Dendrin PF15498.6 EMC96279.1 - 0.046 12.5 1.0 0.07 11.9 1.0 1.2 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin GFO_IDH_MocA PF01408.22 EMC96280.1 - 1.1e-13 52.0 0.0 2.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_1 PF00561.20 EMC96281.1 - 4.4e-15 56.0 0.1 5.7e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC96281.1 - 6e-09 36.8 0.2 8.7e-09 36.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC96281.1 - 2.6e-06 26.9 0.0 3.1e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EMC96281.1 - 0.00059 20.0 0.0 0.00078 19.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydro_lipase PF04083.16 EMC96281.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF915 PF06028.11 EMC96281.1 - 0.21 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) TIG PF01833.24 EMC96282.1 - 1.2e-10 41.3 2.4 7.4e-10 38.8 1.8 2.3 2 0 0 2 2 2 1 IPT/TIG domain MCM_bind PF09739.9 EMC96282.1 - 0.087 11.3 0.0 0.087 11.3 0.0 2.5 2 1 1 3 3 3 0 Mini-chromosome maintenance replisome factor RHD_dimer PF16179.5 EMC96282.1 - 0.12 12.4 1.1 6.4 6.9 0.0 3.6 4 0 0 4 4 4 0 Rel homology dimerisation domain Ank PF00023.30 EMC96282.1 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat Velvet PF11754.8 EMC96285.1 - 5.1e-53 180.6 0.0 2.6e-35 122.6 0.0 3.5 2 2 1 3 3 3 2 Velvet factor ACBP PF00887.19 EMC96287.1 - 9.3e-23 80.3 0.1 2e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein NINJA_B PF16136.5 EMC96287.1 - 0.0025 18.2 3.5 0.0025 18.2 3.5 2.3 2 0 0 2 2 2 1 Putative nuclear localisation signal Amino_oxidase PF01593.24 EMC96287.1 - 0.022 14.1 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF4381 PF14316.6 EMC96287.1 - 0.038 14.2 3.6 0.11 12.8 3.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FERM_M PF00373.18 EMC96287.1 - 0.082 13.3 0.4 0.35 11.3 0.1 2.0 2 0 0 2 2 2 0 FERM central domain MFS_1 PF07690.16 EMC96288.1 - 1.2e-37 129.7 37.9 1.2e-37 129.7 37.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC96288.1 - 2.2e-09 36.7 3.7 2.2e-09 36.7 3.7 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Cellulase PF00150.18 EMC96289.1 - 1.8e-30 106.3 0.8 2.4e-30 106.0 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.18 EMC96290.1 - 8.6e-20 70.9 0.2 1.3e-19 70.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC96290.1 - 2.8e-09 36.9 11.2 5.3e-09 36.1 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EMC96291.1 - 1.6e-84 284.3 23.2 2e-84 284.1 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC96291.1 - 9.3e-14 51.1 43.8 1.1e-12 47.5 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dynein_AAA_lid PF17852.1 EMC96291.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain DUF4818 PF16089.5 EMC96291.1 - 7.3 7.1 10.2 1.6 9.2 0.9 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4818) Amidohydro_2 PF04909.14 EMC96292.1 - 1e-18 68.1 0.1 1.2e-18 68.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Mito_carr PF00153.27 EMC96293.1 - 1.4e-52 175.6 6.0 6.4e-18 64.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 EMC96294.1 - 7.1e-45 153.5 44.5 3e-44 151.4 43.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC96294.1 - 2.3e-21 75.8 14.8 2.3e-21 75.8 14.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMC96294.1 - 4.4e-09 35.7 7.2 4.4e-09 35.7 7.2 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter DUF2583 PF10762.9 EMC96294.1 - 0.12 12.9 0.2 0.43 11.0 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) dCMP_cyt_deam_1 PF00383.23 EMC96295.1 - 3.9e-12 45.9 2.1 6.4e-12 45.2 2.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMC96295.1 - 9.2e-09 35.2 0.7 1.1e-08 34.9 0.7 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 EMC96295.1 - 6.4e-06 26.2 0.7 7.7e-06 25.9 0.7 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 EMC96295.1 - 0.00012 22.1 2.2 0.00023 21.2 2.2 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EMC96295.1 - 0.0003 20.9 1.0 0.00043 20.4 1.0 1.3 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 EMC96295.1 - 0.00059 20.0 1.1 0.00081 19.5 1.1 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 EMC96295.1 - 0.0015 18.7 0.7 0.0021 18.2 0.7 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 EMC96295.1 - 0.002 18.3 1.0 0.0031 17.6 1.0 1.3 1 0 0 1 1 1 1 APOBEC3 Inv-AAD PF18785.1 EMC96295.1 - 0.0054 16.6 0.6 0.011 15.6 0.6 1.5 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase Bd3614-deam PF14439.6 EMC96295.1 - 0.28 11.3 1.5 0.42 10.7 1.5 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase SUI1 PF01253.22 EMC96296.1 - 3.5e-21 75.5 0.0 8.8e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EMC96296.1 - 4.8e-11 43.2 1.5 3e-10 40.6 0.2 2.9 2 1 0 2 2 2 1 Pre-PUA-like domain Kin17_mid PF10357.9 EMC96296.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 EMC96296.1 - 0.028 14.3 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 SWIB/MDM2 domain RepB-RCR_reg PF10723.9 EMC96296.1 - 0.058 13.4 1.4 2.4 8.2 0.4 2.5 2 0 0 2 2 2 0 Replication regulatory protein RepB AMP-binding PF00501.28 EMC96297.1 - 2.4e-87 293.3 0.0 2.9e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.23 EMC96298.1 - 7.3e-20 71.5 17.5 8.9e-20 71.2 17.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2339 PF10101.9 EMC96298.1 - 0.00089 18.0 8.3 0.0011 17.7 8.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Tetraspanin PF00335.20 EMC96298.1 - 5.3 6.7 10.4 15 5.2 10.4 1.7 1 1 0 1 1 1 0 Tetraspanin family WLM PF08325.10 EMC96299.1 - 1.1e-49 169.2 0.0 1.6e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EMC96299.1 - 0.00069 19.7 0.2 0.0015 18.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 EMC96299.1 - 0.0098 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Baculo_PEP_C PF04513.12 EMC96300.1 - 2.5e-06 27.6 19.5 0.09 12.8 3.6 4.8 4 1 1 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.6 EMC96300.1 - 0.0071 16.4 12.8 0.91 9.6 0.3 5.0 4 0 0 4 4 4 2 Type IV pili methyl-accepting chemotaxis transducer N-term COX5A PF02284.16 EMC96300.1 - 0.011 15.7 0.1 0.046 13.7 0.1 2.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Filament PF00038.21 EMC96300.1 - 0.03 13.9 26.1 0.012 15.2 7.9 4.5 3 2 1 4 4 4 0 Intermediate filament protein FlaC_arch PF05377.11 EMC96300.1 - 0.38 11.2 10.3 21 5.6 0.0 6.2 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) L31 PF09784.9 EMC96300.1 - 0.44 11.0 2.1 31 5.1 0.0 3.6 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 NPV_P10 PF05531.12 EMC96300.1 - 0.56 10.7 19.8 7.2 7.2 0.0 6.5 4 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.11 EMC96300.1 - 0.89 9.0 14.2 0.35 10.3 0.4 4.4 3 2 1 5 5 5 0 Allexivirus 40kDa protein Fib_alpha PF08702.10 EMC96300.1 - 0.93 9.7 19.9 2.3 8.4 0.5 5.7 3 2 3 7 7 7 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.11 EMC96300.1 - 2.9 7.7 11.6 0.48 10.2 0.3 3.9 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF948 PF06103.11 EMC96300.1 - 3.8 7.8 19.8 2.1 8.6 0.0 6.0 4 3 1 5 5 5 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 EMC96300.1 - 8.2 6.8 19.8 14 6.1 0.3 6.7 6 2 2 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TIP49 PF06068.13 EMC96301.1 - 1.3e-152 508.1 0.2 1.5e-152 507.8 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EMC96301.1 - 1.4e-21 76.4 0.3 3.9e-21 75.0 0.1 1.9 2 0 0 2 2 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 EMC96301.1 - 2.9e-08 33.6 0.2 0.00036 20.3 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EMC96301.1 - 5.8e-07 30.0 0.3 0.0033 17.8 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EMC96301.1 - 0.00032 20.1 0.4 0.00057 19.3 0.4 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EMC96301.1 - 0.0029 17.0 0.9 0.064 12.6 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EMC96301.1 - 0.0039 17.6 0.2 0.021 15.2 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EMC96301.1 - 0.004 17.5 1.5 0.39 11.1 0.9 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMC96301.1 - 0.018 15.3 0.0 0.56 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EMC96301.1 - 0.049 13.3 0.1 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EMC96301.1 - 0.057 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EMC96301.1 - 0.076 12.8 1.1 0.44 10.3 1.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMC96301.1 - 0.12 12.3 0.4 15 5.5 0.0 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Hydin_ADK PF17213.3 EMC96301.1 - 0.18 12.1 0.7 0.39 11.0 0.2 1.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Molybdopterin PF00384.22 EMC96302.1 - 3.4e-72 243.7 0.0 7.4e-70 236.1 0.0 2.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EMC96302.1 - 2.2e-20 72.5 0.2 5.7e-20 71.2 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EMC96302.1 - 7.1e-18 65.0 0.1 1.7e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EMC96302.1 - 4.2e-17 61.4 0.2 4.2e-17 61.4 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EMC96302.1 - 1.1e-08 34.9 0.6 1.1e-08 34.9 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EMC96302.1 - 0.013 15.2 0.0 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Lyx_isomer PF07385.12 EMC96302.1 - 0.18 11.1 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase Cys_Met_Meta_PP PF01053.20 EMC96303.1 - 4.2e-153 509.4 0.0 4.8e-153 509.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMC96303.1 - 2.7e-09 36.7 0.0 4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EMC96303.1 - 6.3e-09 35.3 0.1 9.8e-09 34.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMC96303.1 - 2.2e-07 30.5 0.1 3.7e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EMC96303.1 - 1.8e-05 24.2 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EMC96303.1 - 0.00015 20.4 0.0 0.00021 20.0 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase CPSase_L_D2 PF02786.17 EMC96303.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Asparaginase_C PF17763.1 EMC96303.1 - 0.14 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain TRAPPC10 PF12584.8 EMC96304.1 - 1.1e-19 70.7 0.0 2.2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 QCR10 PF09796.9 EMC96305.1 - 1.2e-25 89.3 0.1 1.6e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Na_H_Exchanger PF00999.21 EMC96307.1 - 2.3e-45 155.1 18.2 2.9e-45 154.7 18.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family adh_short_C2 PF13561.6 EMC96308.1 - 2.9e-59 200.5 2.4 3.6e-59 200.1 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC96308.1 - 1.4e-46 158.5 2.8 1.7e-46 158.2 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EMC96308.1 - 0.068 13.0 0.7 0.098 12.5 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EMC96309.1 - 2.2e-23 82.6 0.5 4.2e-23 81.7 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC96309.1 - 1e-15 59.0 0.0 2.4e-15 57.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC96309.1 - 7.6e-11 41.9 0.0 2.5e-09 37.0 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrmE_N PF10396.9 EMC96309.1 - 0.13 12.6 0.0 0.49 10.7 0.0 1.8 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus Abhydrolase_6 PF12697.7 EMC96311.1 - 2.6e-08 34.7 0.3 3.5e-08 34.3 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC96311.1 - 0.00012 21.4 0.1 0.0012 18.1 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AA_permease_2 PF13520.6 EMC96312.1 - 5.6e-44 150.6 45.2 7.4e-44 150.2 45.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC96312.1 - 2.4e-19 69.3 35.7 3.7e-19 68.7 35.7 1.2 1 0 0 1 1 1 1 Amino acid permease Alk_phosphatase PF00245.20 EMC96313.1 - 5.2e-68 229.9 0.3 3.3e-67 227.3 0.3 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EMC96313.1 - 2.5e-05 23.9 0.9 0.00038 19.9 0.2 2.4 1 1 1 2 2 2 1 Sulfatase DUF229 PF02995.17 EMC96313.1 - 0.00057 18.6 0.1 0.00082 18.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 EMC96313.1 - 0.0065 16.1 1.2 0.014 15.0 1.1 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EMC96313.1 - 0.049 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1501 PF07394.12 EMC96313.1 - 0.13 11.2 2.0 0.19 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) XRCC4 PF06632.12 EMC96314.1 - 4.1e-12 45.6 1.4 4.1e-12 45.6 1.4 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Baculo_PEP_C PF04513.12 EMC96314.1 - 0.012 15.6 2.2 0.022 14.8 2.1 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TT1725 PF18324.1 EMC96314.1 - 0.013 15.6 0.1 0.051 13.7 0.0 2.0 2 1 0 2 2 2 0 Hypothetical protein TT1725 RNA_pol_Rpc82 PF05645.13 EMC96319.1 - 9.9e-37 127.1 0.0 3e-31 109.1 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EMC96319.1 - 5.8e-13 48.7 0.2 2.7e-09 37.0 0.2 3.2 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EMC96319.1 - 3.2e-09 36.6 1.1 0.00054 19.8 0.0 2.7 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.19 EMC96319.1 - 0.0018 18.1 0.1 0.047 13.6 0.0 2.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF2336 PF10098.9 EMC96319.1 - 0.0075 15.8 4.9 0.44 10.0 0.6 2.7 3 0 0 3 3 3 2 Uncharacterised protein conserved in bacteria (DUF2336) HTH_DeoR PF08220.12 EMC96319.1 - 0.039 13.7 0.2 13 5.7 0.0 3.8 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain Peptidase_M16_C PF05193.21 EMC96320.1 - 5.5e-14 52.6 0.0 8.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMC96320.1 - 1.5e-12 47.7 0.0 2.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) HTH_Tnp_1 PF01527.20 EMC96320.1 - 0.22 11.9 2.7 1.5 9.2 0.0 3.0 3 0 0 3 3 3 0 Transposase Transcrip_reg PF01709.20 EMC96321.1 - 3e-67 226.6 0.6 3.4e-67 226.4 0.6 1.0 1 0 0 1 1 1 1 Transcriptional regulator PolyA_pol PF01743.20 EMC96321.1 - 0.068 13.6 0.1 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 Poly A polymerase head domain PhoLip_ATPase_C PF16212.5 EMC96322.1 - 7.6e-56 189.6 4.1 1.7e-55 188.5 4.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMC96322.1 - 6.2e-16 57.8 0.2 1.3e-15 56.8 0.2 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EMC96322.1 - 1.2e-12 48.5 5.5 7.8e-09 36.1 1.0 3.4 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EMC96322.1 - 3.2e-07 30.0 0.6 0.0025 17.3 0.0 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 EMC96322.1 - 3.7e-06 26.9 0.0 6.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMC96322.1 - 0.0096 15.7 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EMC96322.1 - 0.13 12.4 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Cupin_1 PF00190.22 EMC96323.1 - 1.4e-38 131.9 1.2 2.7e-20 72.5 0.1 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EMC96323.1 - 4.7e-24 83.9 0.3 1.3e-11 44.0 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EMC96323.1 - 3.2e-08 33.2 0.1 0.008 15.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EMC96323.1 - 3.8e-08 33.3 0.1 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EMC96323.1 - 9.9e-07 28.8 0.0 3e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.12 EMC96323.1 - 0.00039 20.1 0.0 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.7 EMC96323.1 - 0.021 14.6 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Cupin ARD PF03079.14 EMC96323.1 - 0.022 15.0 0.1 0.082 13.1 0.0 1.8 2 0 0 2 2 2 0 ARD/ARD' family Cupin_4 PF08007.12 EMC96323.1 - 0.037 13.5 0.0 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 Cupin superfamily protein Auxin_BP PF02041.16 EMC96323.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Auxin binding protein cNMP_binding PF00027.29 EMC96323.1 - 0.053 13.6 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Cellulase PF00150.18 EMC96325.1 - 1.7e-20 73.6 7.9 3.7e-20 72.5 7.9 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GspL_C PF12693.7 EMC96326.1 - 0.49 10.2 7.7 0.82 9.5 7.0 1.7 1 1 0 1 1 1 0 GspL periplasmic domain TMF_TATA_bd PF12325.8 EMC96326.1 - 2.6 8.3 13.6 0.22 11.8 1.6 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.6 EMC96326.1 - 3.5 7.7 21.7 16 5.6 13.8 3.2 2 1 0 2 2 2 0 FlxA-like protein Es2 PF09751.9 EMC96327.1 - 8e-125 418.0 9.3 9.5e-125 417.7 9.3 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 JmjC PF02373.22 EMC96328.1 - 1.4e-40 138.3 0.5 3.2e-40 137.1 0.5 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 EMC96328.1 - 5.5e-20 71.4 2.0 1.3e-19 70.3 2.0 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EMC96328.1 - 5.9e-18 65.0 1.9 1.2e-17 64.1 1.9 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 EMC96328.1 - 2.5e-14 52.9 2.7 9.6e-14 51.1 2.7 2.1 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 EMC96328.1 - 1.7 8.6 6.3 4.5 7.3 6.3 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EMC96328.1 - 2.2 8.6 7.0 6.1 7.2 7.0 1.8 1 0 0 1 1 1 0 RING-like domain CFIA_Pcf11 PF11526.8 EMC96329.1 - 0.00011 22.7 0.0 0.00033 21.1 0.0 1.9 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 EMC96329.1 - 0.00076 20.3 0.0 0.0042 17.9 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 EMC96329.1 - 0.00096 19.0 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 VHS domain zf_UBZ PF18439.1 EMC96329.1 - 0.12 12.0 5.6 0.1 12.2 1.0 2.7 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Inhibitor_I9 PF05922.16 EMC96330.1 - 0.056 14.1 0.0 0.064 13.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 HLH PF00010.26 EMC96331.1 - 1.9e-12 46.9 0.0 3.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 EMC96331.1 - 0.0035 17.5 0.6 0.018 15.3 0.1 2.2 3 0 0 3 3 3 1 Homeobox associated leucine zipper SAE2 PF08573.10 EMC96332.1 - 4.1e-22 79.4 4.7 5.6e-21 75.7 4.7 2.3 1 1 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus F-box PF00646.33 EMC96333.1 - 0.00039 20.2 0.3 0.00068 19.5 0.3 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMC96333.1 - 0.0016 18.3 0.2 0.003 17.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like zf-CCHC PF00098.23 EMC96334.1 - 3.4e-23 80.6 30.0 3.2e-09 36.4 3.0 4.9 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.6 EMC96334.1 - 8e-07 28.9 16.5 0.0031 17.4 0.2 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 EMC96334.1 - 4.1e-05 23.2 17.2 0.11 12.2 0.7 3.1 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.6 EMC96334.1 - 0.0022 17.8 20.3 0.24 11.3 1.7 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 EMC96334.1 - 0.084 12.6 1.2 0.084 12.6 1.2 3.5 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger NinD PF17466.2 EMC96334.1 - 9.7 6.4 8.9 4 7.6 0.3 3.0 3 0 0 3 3 3 0 Family of unknown function SNRNP27 PF08648.12 EMC96335.1 - 4.7e-24 84.2 2.4 7.8e-24 83.5 2.4 1.3 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins tRNA-synt_1c PF00749.21 EMC96337.1 - 6.5e-98 327.5 0.0 1.8e-97 326.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EMC96337.1 - 8.1e-31 107.2 0.0 1.8e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Zn_clus PF00172.18 EMC96338.1 - 4.3e-10 39.6 9.5 7.9e-10 38.7 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMC96338.1 - 1.7e-08 33.7 0.2 2.6e-08 33.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Macro PF01661.21 EMC96340.1 - 3e-39 133.7 0.2 5.2e-39 132.9 0.2 1.4 1 0 0 1 1 1 1 Macro domain Ank_4 PF13637.6 EMC96341.1 - 1.3e-10 41.5 1.9 8.5e-05 23.0 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC96341.1 - 3.4e-10 39.3 1.9 0.0021 18.4 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EMC96341.1 - 2.2e-09 37.8 0.2 0.00049 20.6 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EMC96341.1 - 4.6e-07 30.0 1.8 0.078 13.5 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EMC96341.1 - 2.3e-06 27.8 1.6 0.062 13.6 0.1 3.8 2 2 1 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EMC96341.1 - 0.0008 19.2 0.2 0.009 15.8 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain FapA PF03961.13 EMC96341.1 - 0.68 8.5 2.2 0.67 8.5 0.7 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A UPF0242 PF06785.11 EMC96341.1 - 1.5 8.9 5.9 1.7 8.7 4.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Complex1_LYR PF05347.15 EMC96342.1 - 1.2e-05 25.3 0.8 3.1e-05 24.0 0.8 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) BTB PF00651.31 EMC96343.1 - 6.2e-13 49.0 0.1 1.2e-12 48.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zinc_ribbon_6 PF14599.6 EMC96343.1 - 0.17 11.9 1.9 0.38 10.8 1.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon Nnf1 PF03980.14 EMC96343.1 - 0.23 11.9 1.9 0.47 10.9 1.9 1.5 1 0 0 1 1 1 0 Nnf1 BTB PF00651.31 EMC96344.1 - 6.4e-15 55.3 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4883 PF16224.5 EMC96344.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) SNF2_N PF00176.23 EMC96345.1 - 2.5e-64 217.2 0.0 2.2e-63 214.1 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC96345.1 - 3.1e-23 82.3 0.0 2.2e-21 76.3 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC96345.1 - 3.4e-07 30.4 0.0 1.9e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EMC96345.1 - 1.6e-05 24.2 1.6 0.056 12.6 0.0 3.9 3 1 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 Glyco_tranf_2_3 PF13641.6 EMC96347.1 - 1.7e-22 80.5 0.0 2.9e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EMC96347.1 - 2.7e-08 34.0 0.7 2.7e-08 34.0 0.7 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMC96347.1 - 5.5e-05 23.0 0.0 9.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EMC96347.1 - 0.00017 21.1 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 EMC96347.1 - 0.083 13.4 0.0 16 6.1 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 COX14 PF14880.6 EMC96347.1 - 0.21 11.5 1.3 0.97 9.3 0.0 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Apc15p PF05841.11 EMC96349.1 - 5.6e-12 46.6 3.6 6.8e-12 46.3 1.0 2.3 2 0 0 2 2 2 1 Apc15p protein Use1 PF09753.9 EMC96350.1 - 2.7e-06 27.3 0.0 9e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 RabGAP-TBC PF00566.18 EMC96351.1 - 2.7e-36 125.3 6.8 5.8e-36 124.2 6.8 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EMC96351.1 - 3e-12 46.3 0.1 5.9e-07 29.1 0.2 3.2 2 1 1 3 3 3 3 Rab-binding domain (RBD) Peptidase_M60 PF13402.6 EMC96351.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.5 1 1 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like 2-Hacid_dh_C PF02826.19 EMC96352.1 - 1.1e-44 151.9 0.0 2.2e-44 151.0 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMC96352.1 - 4.3e-06 26.4 0.0 1.5e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.21 EMC96352.1 - 0.0063 16.3 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.16 EMC96352.1 - 0.058 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LIM PF00412.22 EMC96355.1 - 1.9e-21 76.0 34.0 4.4e-10 39.6 1.0 5.4 6 0 0 6 6 6 4 LIM domain Helo_like_N PF17111.5 EMC96355.1 - 0.00027 20.4 1.0 0.00052 19.4 1.0 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Cut8 PF08559.10 EMC96355.1 - 0.0015 18.2 0.3 0.0027 17.4 0.3 1.3 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Coq4 PF05019.13 EMC96355.1 - 0.19 11.1 0.2 1.4 8.2 0.1 2.1 2 0 0 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SesA PF17107.5 EMC96355.1 - 1 9.6 3.1 0.72 10.1 0.1 2.3 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PH_4 PF15404.6 EMC96356.1 - 5.6e-62 208.8 0.0 1.2e-61 207.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 EMC96356.1 - 1.3e-20 72.8 0.2 3.8e-20 71.3 0.2 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 EMC96356.1 - 3.9e-05 24.1 0.0 3 8.4 0.0 5.2 4 1 0 4 4 4 1 PH domain PH_6 PF15406.6 EMC96356.1 - 0.039 14.2 4.1 0.061 13.6 0.1 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain PH_13 PF16652.5 EMC96356.1 - 0.13 12.1 0.3 7.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain NAD_binding_2 PF03446.15 EMC96357.1 - 6.6e-34 117.4 0.1 8.8e-34 117.0 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EMC96357.1 - 2.2e-22 79.5 0.0 3.6e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF656 PF04920.12 EMC96357.1 - 0.028 14.3 0.0 0.098 12.6 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF656) DUF3636 PF12331.8 EMC96358.1 - 2.1e-45 154.2 0.1 4.7e-45 153.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 EMC96358.1 - 0.00055 18.6 4.2 0.0092 14.5 1.2 2.6 2 1 1 3 3 3 2 DNA damage checkpoint protein SPRY PF00622.28 EMC96359.1 - 2.2e-17 63.3 0.0 3.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Ham1p_like PF01725.16 EMC96359.1 - 0.18 11.7 0.0 0.76 9.7 0.0 1.8 2 0 0 2 2 2 0 Ham1 family Phosphorylase PF00343.20 EMC96360.1 - 0 1060.5 0.0 0 1060.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase CTP_transf_1 PF01148.20 EMC96361.1 - 1.6e-80 270.7 24.7 2e-80 270.4 24.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SLC3A2_N PF16028.5 EMC96361.1 - 0.24 11.0 2.4 0.65 9.6 0.1 2.8 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus adh_short PF00106.25 EMC96362.1 - 1.4e-34 119.3 0.7 7.8e-34 116.8 0.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96362.1 - 1.1e-20 74.2 1.1 2.8e-20 72.9 1.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96362.1 - 1.7e-11 44.4 0.1 2.1e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC96362.1 - 1.6e-08 34.3 0.1 2e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMC96362.1 - 0.017 14.2 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EMC96362.1 - 0.019 14.4 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cullin PF00888.22 EMC96363.1 - 4.8e-182 606.8 13.9 7.3e-182 606.2 13.9 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EMC96363.1 - 1.6e-28 98.5 4.2 6.2e-28 96.6 4.2 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 EMC96363.1 - 0.067 13.7 3.6 0.38 11.3 1.2 3.0 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal WGG PF10273.9 EMC96363.1 - 3.3 8.4 5.9 61 4.4 0.1 3.9 3 1 0 3 3 3 0 Pre-rRNA-processing protein TSR2 Swm2 PF17083.5 EMC96363.1 - 6.1 6.9 8.0 0.31 11.1 0.2 2.8 2 1 1 3 3 3 0 Nucleolar protein Swm2 HEAT_EZ PF13513.6 EMC96364.1 - 8.5e-24 83.6 15.1 3.8e-12 46.4 0.0 8.5 7 2 1 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 EMC96364.1 - 3.8e-19 68.9 4.7 0.0055 17.1 0.0 8.2 5 2 3 8 8 8 4 HEAT repeats HEAT PF02985.22 EMC96364.1 - 6.7e-18 63.3 16.0 0.0041 17.3 0.0 10.6 12 0 0 12 12 12 4 HEAT repeat Vac14_Fab1_bd PF12755.7 EMC96364.1 - 4.1e-13 49.7 0.1 0.0039 17.8 0.0 6.6 5 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EMC96364.1 - 1.9e-10 41.0 0.0 0.0035 17.4 0.0 4.3 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EMC96364.1 - 1.2e-09 37.9 0.0 9.6e-08 31.8 0.0 4.1 3 1 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EMC96364.1 - 3e-05 22.8 0.0 0.0072 14.9 0.0 3.2 2 1 1 4 4 4 1 Adaptin N terminal region CLASP_N PF12348.8 EMC96364.1 - 0.00027 20.6 0.1 17 4.9 0.0 6.1 5 1 0 5 5 5 0 CLASP N terminal TAF6_C PF07571.13 EMC96364.1 - 0.0078 16.5 0.0 1.8 8.9 0.0 4.0 5 0 0 5 5 4 1 TAF6 C-terminal HEAT repeat domain Xpo1 PF08389.12 EMC96364.1 - 0.016 15.2 0.1 4.1 7.5 0.0 4.2 4 2 0 4 4 4 0 Exportin 1-like protein Arm PF00514.23 EMC96364.1 - 0.058 13.5 5.6 15 5.8 0.0 5.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EMC96364.1 - 0.06 14.0 2.6 40 5.3 0.0 5.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Es2 PF09751.9 EMC96364.1 - 0.065 13.0 0.6 0.1 12.3 0.6 1.2 1 0 0 1 1 1 0 Nuclear protein Es2 Ribosomal_60s PF00428.19 EMC96364.1 - 0.81 10.3 7.2 0.7 10.5 4.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Importin_rep_4 PF18808.1 EMC96364.1 - 1.4 9.3 7.9 4.3 7.7 0.3 3.8 4 0 0 4 4 4 0 Importin repeat Tti2 PF10521.9 EMC96364.1 - 3.1 7.3 4.5 92 2.4 0.0 3.7 4 0 0 4 4 4 0 Tti2 family TPK_catalytic PF04263.16 EMC96366.1 - 2.1e-30 105.2 0.0 3.1e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EMC96366.1 - 1.5e-18 66.3 0.1 2.8e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Hydrolase_4 PF12146.8 EMC96366.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CHCH PF06747.13 EMC96367.1 - 2.3e-07 30.8 3.3 3.8e-07 30.1 3.3 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EMC96367.1 - 5.7e-05 23.5 0.9 9.3e-05 22.8 0.9 1.3 1 0 0 1 1 1 1 GCK domain E1-E2_ATPase PF00122.20 EMC96368.1 - 2.8e-18 66.1 0.0 8e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EMC96368.1 - 7.8e-18 65.5 1.1 3.8e-11 43.7 0.8 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMC96368.1 - 0.0021 17.8 0.2 0.052 13.3 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase MRJP PF03022.16 EMC96369.1 - 3.9e-21 75.7 0.0 6.6e-21 74.9 0.0 1.3 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 EMC96369.1 - 0.064 12.8 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Pkinase PF00069.25 EMC96370.1 - 1.9e-66 224.1 0.0 2.5e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC96370.1 - 6.2e-32 110.9 0.0 8.2e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMC96370.1 - 1.2e-06 27.7 0.1 1.6e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EMC96370.1 - 3.8e-05 23.1 0.0 7.3e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMC96370.1 - 0.00037 19.9 0.0 0.022 14.1 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EMC96370.1 - 0.00059 19.8 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMC96370.1 - 0.0054 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EMC96370.1 - 0.01 15.4 0.2 0.023 14.3 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Get5_C PF18514.1 EMC96370.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Get5 C-terminal domain Myb_DNA-bind_7 PF15963.5 EMC96370.1 - 0.38 10.7 1.2 0.7 9.8 0.2 2.0 2 0 0 2 2 2 0 Myb DNA-binding like G-alpha PF00503.20 EMC96371.1 - 6.9e-118 393.8 1.7 7.9e-118 393.6 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EMC96371.1 - 5.5e-16 58.5 1.0 5.8e-11 42.2 0.3 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMC96371.1 - 4.1e-06 26.3 0.2 0.066 12.6 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EMC96371.1 - 0.0006 20.0 0.1 0.89 9.8 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EMC96371.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EMC96371.1 - 0.13 11.8 0.1 1.6 8.3 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMC96371.1 - 0.17 12.0 0.1 24 5.0 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase Chitin_synth_2 PF03142.15 EMC96372.1 - 1.4e-23 83.3 2.6 8.5e-23 80.8 1.4 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EMC96372.1 - 1.7e-14 54.2 4.4 1.7e-14 54.2 4.4 2.6 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMC96372.1 - 1.4e-11 44.7 0.0 3.5e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMC96372.1 - 0.00027 20.8 0.1 0.024 14.4 0.1 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 CybS PF05328.12 EMC96372.1 - 0.017 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit SNF2_N PF00176.23 EMC96373.1 - 8e-72 241.9 0.1 1.4e-71 241.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC96373.1 - 6.5e-15 55.4 0.0 2e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC96373.1 - 2.1e-06 27.8 0.0 4.9e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMC96373.1 - 4.2e-05 23.4 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 EMC96373.1 - 0.00014 21.7 3.9 0.00039 20.3 3.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain ERCC3_RAD25_C PF16203.5 EMC96373.1 - 0.04 13.1 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF489 PF04356.12 EMC96373.1 - 0.057 13.4 0.9 0.58 10.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF489) Zn-ribbon_8 PF09723.10 EMC96373.1 - 0.11 12.6 4.6 0.2 11.8 2.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Nudix_N_2 PF14803.6 EMC96373.1 - 0.36 10.8 3.0 0.42 10.6 0.5 2.5 3 0 0 3 3 3 0 Nudix N-terminal zf-C3HC4 PF00097.25 EMC96373.1 - 0.54 10.2 3.8 0.21 11.5 0.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PI3_PI4_kinase PF00454.27 EMC96374.1 - 3.5e-39 135.1 0.0 8.2e-39 133.9 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.27 EMC96375.1 - 5.8e-16 57.8 2.7 1.1e-15 56.9 2.7 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EMC96375.1 - 0.0044 16.5 0.7 0.0076 15.7 0.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding MAD PF05557.13 EMC96375.1 - 0.026 12.9 1.3 0.032 12.6 1.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein BLOC1_2 PF10046.9 EMC96375.1 - 0.054 13.8 0.1 0.09 13.1 0.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 EMC96375.1 - 0.073 12.4 0.7 0.11 11.9 0.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EMC96375.1 - 0.11 11.4 1.1 0.15 11.0 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Zn-ribbon_8 PF09723.10 EMC96375.1 - 0.14 12.3 0.2 0.27 11.4 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain BMFP PF04380.13 EMC96375.1 - 0.32 11.5 9.1 0.3 11.6 7.1 1.9 2 0 0 2 2 2 0 Membrane fusogenic activity DivIC PF04977.15 EMC96375.1 - 0.81 9.5 4.0 1.4 8.7 2.9 1.8 1 1 1 2 2 2 0 Septum formation initiator SRRM_C PF15230.6 EMC96375.1 - 5.7 7.6 9.3 0.55 10.8 3.8 2.1 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Cupin_2 PF07883.11 EMC96376.1 - 2e-15 56.2 0.1 4.6e-09 35.9 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EMC96376.1 - 3.6e-08 33.0 0.0 0.0018 18.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EMC96376.1 - 4.7e-05 23.0 1.3 0.092 12.4 0.1 3.3 2 1 1 3 3 3 1 Cupin MannoseP_isomer PF01050.18 EMC96376.1 - 0.00013 21.9 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase EutQ PF06249.12 EMC96376.1 - 0.00096 18.9 0.0 0.075 12.8 0.0 2.8 2 1 1 3 3 3 1 Ethanolamine utilisation protein EutQ FdtA PF05523.11 EMC96376.1 - 0.002 17.8 0.1 0.047 13.4 0.0 2.3 2 0 0 2 2 2 1 WxcM-like, C-terminal AraC_binding PF02311.19 EMC96376.1 - 0.0065 16.4 0.3 0.045 13.7 0.4 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain CENP-C_C PF11699.8 EMC96376.1 - 0.012 15.8 0.0 0.62 10.3 0.0 2.9 2 1 1 3 3 3 0 Mif2/CENP-C like Cupin_6 PF12852.7 EMC96376.1 - 0.014 15.2 0.0 0.048 13.4 0.0 1.8 2 0 0 2 2 2 0 Cupin AraC_binding_2 PF14525.6 EMC96376.1 - 0.035 13.8 0.0 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 AraC-binding-like domain Cupin_4 PF08007.12 EMC96376.1 - 0.11 11.9 0.5 13 5.1 0.0 2.5 3 0 0 3 3 3 0 Cupin superfamily protein Abhydrolase_3 PF07859.13 EMC96377.1 - 1.5e-07 31.5 0.0 2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC96377.1 - 4.3e-05 22.6 0.1 7.1e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EMC96377.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase GMC_oxred_N PF00732.19 EMC96378.1 - 3.4e-55 187.5 0.0 7.9e-55 186.3 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC96378.1 - 2.9e-37 128.4 0.0 4.9e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EMC96378.1 - 3.2e-05 23.2 1.2 5e-05 22.5 1.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EMC96378.1 - 0.032 13.5 0.4 0.083 12.1 0.4 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EMC96378.1 - 0.04 14.2 1.7 0.4 11.0 0.6 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMC96378.1 - 0.051 12.6 3.7 0.22 10.6 2.8 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EMC96378.1 - 0.17 11.1 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC96378.1 - 0.29 10.7 4.5 0.2 11.2 1.9 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase zf-H2C2_2 PF13465.6 EMC96379.1 - 1.3e-08 34.8 5.8 0.00017 21.9 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EMC96379.1 - 1.7e-08 34.4 13.3 8.9e-05 22.7 1.8 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC96379.1 - 2.6e-08 34.0 10.9 0.00083 20.0 1.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-ACC PF17848.1 EMC96379.1 - 0.0011 19.0 0.2 0.012 15.6 0.0 2.7 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain zf-BED PF02892.15 EMC96379.1 - 0.012 15.6 0.4 0.012 15.6 0.4 3.0 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.6 EMC96379.1 - 0.014 15.4 2.2 0.014 15.4 2.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EMC96379.1 - 0.015 15.4 3.5 0.086 13.0 0.8 2.8 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 EMC96379.1 - 0.018 14.8 3.0 0.018 14.8 3.0 3.4 3 1 0 3 3 3 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 EMC96379.1 - 0.049 14.4 4.9 0.12 13.2 0.3 2.5 1 1 2 3 3 3 0 zinc-ribbon family PyrI_C PF02748.15 EMC96379.1 - 0.075 13.0 0.4 16 5.5 0.0 3.2 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HypA PF01155.19 EMC96379.1 - 0.13 12.3 4.1 0.6 10.2 1.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PHD_4 PF16866.5 EMC96379.1 - 0.81 9.8 5.3 21 5.3 5.2 2.5 1 1 0 1 1 1 0 PHD-finger zinc_ribbon_4 PF13717.6 EMC96379.1 - 1.1 9.2 4.5 40 4.3 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain C1_2 PF03107.16 EMC96379.1 - 1.2 9.5 4.6 12 6.3 2.0 3.1 2 1 0 2 2 2 0 C1 domain RNHCP PF12647.7 EMC96379.1 - 1.7 8.6 8.0 0.6 10.1 0.6 3.0 2 1 1 3 3 3 0 RNHCP domain zf-C2H2_2 PF12756.7 EMC96379.1 - 2.9 8.3 7.0 0.42 11.0 0.3 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SWIRM PF04433.17 EMC96380.1 - 2.8e-32 110.9 0.1 7.3e-32 109.6 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EMC96380.1 - 3.1e-26 91.1 13.7 5.4e-26 90.4 13.7 1.4 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EMC96380.1 - 9.8e-10 38.5 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC96380.1 - 0.00032 20.9 0.0 0.00069 19.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EMC96380.1 - 0.044 13.6 7.0 2.2 8.1 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, ZZ type FAD_binding_3 PF01494.19 EMC96381.1 - 2.5e-10 40.1 0.6 0.0015 17.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 EMC96381.1 - 9.6e-07 28.3 0.0 0.00012 21.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC96381.1 - 1.9e-05 24.0 0.0 3.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMC96381.1 - 8.4e-05 22.7 0.1 0.00027 21.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EMC96381.1 - 0.00076 18.7 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMC96381.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC96381.1 - 0.0019 17.0 0.1 0.0042 15.8 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EMC96381.1 - 0.016 14.5 0.0 0.054 12.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC96381.1 - 0.029 14.0 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EMC96381.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EMC96382.1 - 7e-24 84.4 0.0 1.7e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96382.1 - 3.3e-17 62.8 0.0 1.2e-10 41.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96382.1 - 3.2e-07 30.4 0.3 7e-07 29.3 0.3 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMC96382.1 - 0.05 12.7 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 EMC96383.1 - 2.6e-78 263.9 26.8 3e-78 263.7 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC96383.1 - 3e-23 82.3 37.8 5.5e-20 71.6 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMC96383.1 - 2.5 6.3 12.9 0.042 12.2 0.4 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 EMC96385.1 - 2.3e-64 217.8 0.0 3.9e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Tad PF13400.6 EMC96385.1 - 0.12 12.7 1.3 0.3 11.4 1.3 1.6 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like IstB_IS21 PF01695.17 EMC96386.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Peptidase_S24 PF00717.23 EMC96387.1 - 4.5e-08 32.9 0.2 2.7e-07 30.5 0.1 2.2 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 EMC96387.1 - 1.7e-06 27.9 0.0 1.9e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S29 PF02907.15 EMC96387.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Iso_dh PF00180.20 EMC96388.1 - 3.1e-82 276.5 0.0 3.6e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FYVE PF01363.21 EMC96389.1 - 4.1e-23 81.3 20.5 1e-16 60.8 4.1 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EMC96389.1 - 7.7e-19 67.1 1.2 2.5e-18 65.5 1.2 2.0 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 EMC96389.1 - 0.00042 20.4 3.0 0.00042 20.4 3.0 3.7 3 1 1 4 4 4 1 AN1-like Zinc finger zf-C2H2_4 PF13894.6 EMC96389.1 - 0.0098 16.7 27.0 0.17 12.8 1.9 6.4 5 1 1 6 6 6 2 C2H2-type zinc finger zf-Di19 PF05605.12 EMC96389.1 - 0.033 14.5 0.1 0.033 14.5 0.1 3.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Gon7 PF08738.10 EMC96389.1 - 0.068 13.3 0.1 0.24 11.5 0.1 1.9 1 0 0 1 1 1 0 Gon7 family IBR PF01485.21 EMC96389.1 - 0.11 12.8 12.1 0.4 10.9 1.2 3.5 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain T3SSipB PF16535.5 EMC96389.1 - 0.46 11.0 4.5 3.9 7.9 0.3 2.6 2 0 0 2 2 2 0 Type III cell invasion protein SipB Allexi_40kDa PF05549.11 EMC96389.1 - 0.46 10.0 3.0 12 5.3 0.0 3.0 3 0 0 3 3 3 0 Allexivirus 40kDa protein CDC24_OB3 PF17244.2 EMC96389.1 - 0.68 9.6 2.5 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 FlxA PF14282.6 EMC96389.1 - 0.89 9.6 9.3 0.6 10.1 0.8 2.8 2 0 0 2 2 2 0 FlxA-like protein zf-C2HC5 PF06221.13 EMC96389.1 - 2 8.4 18.4 1.4 9.0 0.2 4.7 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_15 PF17032.5 EMC96389.1 - 5.8 7.7 16.0 12 6.8 0.6 4.6 4 1 0 4 4 4 0 zinc-ribbon family NAD_binding_7 PF13241.6 EMC96390.1 - 5e-31 107.2 0.0 8e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EMC96390.1 - 3.7e-29 100.2 0.1 5.8e-29 99.5 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EMC96390.1 - 1.3e-14 53.3 0.2 2.5e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 EMC96390.1 - 0.00039 19.8 0.0 0.00055 19.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EMC96390.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EMC96390.1 - 0.092 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GLTP PF08718.11 EMC96391.1 - 9.1e-46 155.8 0.0 1.5e-45 155.1 0.0 1.3 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Methyltransf_10 PF05971.12 EMC96392.1 - 3.7e-60 203.8 0.0 5.3e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EMC96392.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EMC96392.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EMC96392.1 - 0.06 14.0 0.0 0.19 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 EMC96392.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SVWC PF15430.6 EMC96393.1 - 0.047 14.0 0.2 0.064 13.5 0.2 1.2 1 0 0 1 1 1 0 Single domain von Willebrand factor type C BAR_2 PF10455.9 EMC96394.1 - 1e-53 182.4 0.2 1.5e-53 181.8 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EMC96394.1 - 1.1e-17 64.5 6.3 3.3e-16 59.7 6.3 2.1 1 1 0 1 1 1 1 BAR domain Pex19 PF04614.12 EMC96394.1 - 0.047 13.5 0.4 0.047 13.5 0.4 2.1 1 1 1 2 2 2 0 Pex19 protein family SKA2 PF16740.5 EMC96394.1 - 0.11 12.3 2.4 0.29 10.9 0.1 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 MCM_lid PF17855.1 EMC96397.1 - 0.0002 21.7 0.1 0.0017 18.7 0.0 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain 7TMR-HDED PF07697.11 EMC96397.1 - 0.001 19.2 2.6 0.0023 18.1 2.6 1.5 1 1 0 1 1 1 1 7TM-HD extracellular ABC_tran_CTD PF16326.5 EMC96398.1 - 0.48 10.7 5.7 0.59 10.4 2.7 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain Phage_tail_APC PF16778.5 EMC96398.1 - 2.1 8.3 5.2 5.2 7.0 2.3 2.9 2 1 1 3 3 3 0 Phage tail assembly chaperone protein Mito_carr PF00153.27 EMC96401.1 - 6.8e-29 99.6 2.2 5.4e-15 55.1 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.21 EMC96405.1 - 2.7e-71 240.9 0.3 4.6e-68 230.2 0.0 2.1 2 0 0 2 2 2 2 Amidase adh_short PF00106.25 EMC96406.1 - 1.1e-34 119.6 0.2 1.3e-34 119.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96406.1 - 7.6e-27 94.4 0.1 1.1e-26 93.9 0.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96406.1 - 1.3e-16 61.0 0.0 1.8e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMC96406.1 - 3.7e-09 36.1 0.1 4.6e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMC96406.1 - 4.4e-07 29.6 0.1 1.3e-06 28.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC96406.1 - 0.0037 16.7 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EMC96406.1 - 0.025 14.7 0.1 0.1 12.6 0.1 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2625 PF10946.8 EMC96406.1 - 0.026 13.6 0.1 0.042 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2625 ThiF PF00899.21 EMC96406.1 - 0.047 13.0 0.1 0.96 8.7 0.0 2.1 2 0 0 2 2 2 0 ThiF family Glyco_tran_WecB PF03808.13 EMC96406.1 - 0.15 12.0 0.0 0.76 9.7 0.0 2.0 2 1 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family WW PF00397.26 EMC96407.1 - 4.7e-10 39.4 7.6 8.6e-10 38.5 7.6 1.5 1 0 0 1 1 1 1 WW domain MFS_1 PF07690.16 EMC96408.1 - 8.7e-36 123.6 59.5 3.1e-35 121.8 58.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC96408.1 - 2.9e-07 29.3 17.7 4e-07 28.8 17.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMC96408.1 - 1.3e-05 24.3 40.0 0.0012 17.8 4.1 3.6 2 1 1 3 3 3 3 Sugar (and other) transporter Plasmid_stab_B PF10784.9 EMC96408.1 - 0.14 12.0 0.1 0.48 10.3 0.1 1.9 1 0 0 1 1 1 0 Plasmid stability protein DUF3483 PF11982.8 EMC96408.1 - 0.5 10.0 5.8 0.16 11.6 0.9 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3483) FAD_binding_6 PF00970.24 EMC96409.1 - 1.1e-08 35.3 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EMC96409.1 - 0.0011 19.6 0.0 0.0055 17.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Suc_Fer-like PF06999.12 EMC96411.1 - 7.9e-58 195.5 0.0 9.8e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Metallophos PF00149.28 EMC96412.1 - 1.7e-10 41.7 1.6 2e-10 41.5 0.6 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 EMC96413.1 - 2.2e-49 167.5 0.1 2e-25 89.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EMC96413.1 - 1.2e-20 74.6 0.3 2.9e-05 24.0 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EMC96413.1 - 1.6e-17 63.7 58.6 1.1e-10 41.1 27.0 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.19 EMC96413.1 - 2e-08 33.9 1.6 0.0034 16.9 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMC96413.1 - 2.3e-07 30.4 1.0 0.0032 17.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMC96413.1 - 8.8e-06 25.7 0.0 0.087 12.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EMC96413.1 - 1e-05 26.1 0.4 0.16 12.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 EMC96413.1 - 0.00052 20.7 0.0 0.0086 16.8 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 EMC96413.1 - 0.00081 19.2 0.0 0.36 10.5 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.6 EMC96413.1 - 0.0034 17.6 0.2 18 5.6 0.0 4.6 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EMC96413.1 - 0.0051 17.2 0.1 1.7 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EMC96413.1 - 0.02 14.6 6.4 1.6 8.4 0.0 3.2 3 1 1 4 4 4 0 AAA domain SRP54 PF00448.22 EMC96413.1 - 0.033 13.8 1.6 2.5 7.7 0.5 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EMC96413.1 - 0.044 14.0 0.5 3.3 7.9 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EMC96413.1 - 0.058 13.7 0.4 2.2 8.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EMC96413.1 - 0.11 12.1 0.1 18 4.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EMC96413.1 - 0.13 11.8 0.1 15 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EMC96413.1 - 0.14 12.0 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain G-alpha PF00503.20 EMC96413.1 - 0.21 10.7 0.0 1 8.5 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit adh_short PF00106.25 EMC96415.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96415.1 - 3.9e-06 26.6 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Iso_dh PF00180.20 EMC96418.1 - 3.4e-99 332.3 0.0 4.1e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EMC96418.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 HHH_2 PF12826.7 EMC96418.1 - 0.15 12.1 0.0 0.92 9.7 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.6 EMC96419.1 - 2.1e-36 125.5 0.0 5.6e-36 124.1 0.0 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 EMC96419.1 - 2.3e-07 30.8 0.3 7.7e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Vps51/Vps67 Sec15 PF04091.12 EMC96419.1 - 0.56 9.6 2.6 7.9 5.8 0.5 2.6 2 1 1 3 3 3 0 Exocyst complex subunit Sec15-like HET PF06985.11 EMC96420.1 - 3.5e-10 40.4 0.0 4.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2026 PF09641.10 EMC96421.1 - 0.061 13.0 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) CAP_N PF01213.19 EMC96422.1 - 1.5e-109 366.4 8.0 1.5e-109 366.4 8.0 2.0 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EMC96422.1 - 3.4e-56 189.2 0.1 4.7e-56 188.8 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EMC96422.1 - 0.066 12.9 1.1 0.37 10.5 0.3 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C zf-RING_2 PF13639.6 EMC96423.1 - 1.6e-13 50.7 7.8 1.6e-13 50.7 7.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EMC96423.1 - 1.3e-12 47.3 2.8 2.6e-12 46.3 2.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EMC96423.1 - 4.7e-10 39.1 7.1 4.7e-10 39.1 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMC96423.1 - 4.6e-09 36.0 10.2 3.8e-07 29.9 2.9 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC96423.1 - 5.6e-07 29.3 15.5 6.3e-06 26.0 6.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMC96423.1 - 7.3e-07 29.4 6.8 7.3e-07 29.4 6.8 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 EMC96423.1 - 9.8e-07 28.9 7.6 0.00029 21.0 5.1 2.6 2 0 0 2 2 2 2 zinc-ribbon zf-RING_5 PF14634.6 EMC96423.1 - 1.9e-05 24.5 4.8 1.9e-05 24.5 4.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMC96423.1 - 2e-05 24.5 2.8 2e-05 24.5 2.8 2.7 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EMC96423.1 - 0.00023 20.9 12.9 0.00076 19.3 5.1 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EMC96423.1 - 0.0023 17.9 2.6 0.0023 17.9 2.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EMC96423.1 - 0.0065 16.1 6.7 0.0065 16.1 6.7 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type HypA PF01155.19 EMC96423.1 - 0.015 15.3 1.0 0.015 15.3 1.0 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_4 PF15227.6 EMC96423.1 - 0.057 13.6 11.8 0.49 10.6 1.6 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.11 EMC96423.1 - 0.074 13.0 0.4 0.074 13.0 0.4 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DZR PF12773.7 EMC96423.1 - 0.22 11.6 8.4 0.58 10.2 1.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 EMC96423.1 - 0.27 11.1 13.5 0.41 10.5 3.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 EMC96423.1 - 0.53 10.3 11.1 0.11 12.5 1.5 2.4 2 1 0 2 2 2 0 zinc-ribbons zf-RING-like PF08746.11 EMC96423.1 - 1 9.7 16.9 0.055 13.8 6.3 2.3 2 0 0 2 2 2 0 RING-like domain PHD PF00628.29 EMC96423.1 - 1.5 8.8 18.0 0.21 11.5 6.0 2.8 2 1 0 2 2 2 0 PHD-finger zf-UDP PF14569.6 EMC96423.1 - 1.6 8.9 5.1 6.5 7.0 0.6 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger AA_permease PF00324.21 EMC96424.1 - 1.8e-131 439.0 44.4 2.1e-131 438.9 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMC96424.1 - 1e-37 130.0 47.9 1.4e-37 129.6 47.9 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 EMC96425.1 - 7.1e-37 127.3 25.5 1.2e-35 123.3 25.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC96425.1 - 3.2e-29 102.0 49.9 1.1e-26 93.6 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EMC96425.1 - 0.015 14.2 5.3 0.16 10.9 1.0 2.7 3 0 0 3 3 3 0 Sugar-tranasporters, 12 TM Ion_trans_2 PF07885.16 EMC96426.1 - 1.5e-28 98.5 26.4 4.7e-17 61.7 3.3 3.2 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 EMC96426.1 - 0.0015 17.9 15.9 0.14 11.4 0.4 3.3 3 0 0 3 3 3 3 Ion transport protein DUF5476 PF17570.2 EMC96426.1 - 0.051 14.0 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5476) Phage_holin_4_2 PF04020.13 EMC96426.1 - 6.6 7.5 12.5 0.17 12.6 2.6 2.8 3 0 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV PPR_2 PF13041.6 EMC96427.1 - 1.6e-21 76.2 0.1 0.00018 21.6 0.0 7.2 6 1 2 8 8 8 4 PPR repeat family PPR_long PF17177.4 EMC96427.1 - 3.5e-14 52.7 4.9 6.2e-11 42.1 0.1 3.7 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EMC96427.1 - 4.6e-14 51.6 0.4 0.052 13.8 0.0 9.0 10 0 0 10 10 10 3 PPR repeat PPR_3 PF13812.6 EMC96427.1 - 4.3e-12 45.9 0.0 0.00011 22.2 0.0 4.2 2 1 3 5 5 5 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 EMC96427.1 - 2e-08 33.8 0.0 0.007 16.0 0.0 5.7 6 0 0 6 6 6 2 PPR repeat BTAD PF03704.17 EMC96427.1 - 0.022 15.2 0.0 0.022 15.2 0.0 3.9 6 0 0 6 6 6 0 Bacterial transcriptional activator domain MRP-S27 PF10037.9 EMC96427.1 - 0.026 13.4 0.0 0.38 9.5 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 DUF3449 PF11931.8 EMC96427.1 - 0.035 13.9 0.9 1.2 8.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) TPR_14 PF13428.6 EMC96427.1 - 0.04 14.8 23.5 4.4 8.4 0.0 9.5 9 1 0 10 10 10 0 Tetratricopeptide repeat TPR_19 PF14559.6 EMC96427.1 - 0.11 13.0 14.6 1.2 9.7 0.0 6.6 10 0 0 10 10 10 0 Tetratricopeptide repeat MFS_1 PF07690.16 EMC96428.1 - 1.2e-24 87.0 29.9 1.7e-24 86.4 29.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily COX14 PF14880.6 EMC96428.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 Cytochrome oxidase c assembly MFS_1 PF07690.16 EMC96429.1 - 3.3e-24 85.5 12.9 6.2e-19 68.1 0.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EMC96429.1 - 2.8e-17 63.0 2.4 7.2e-17 61.7 2.4 1.7 1 0 0 1 1 1 1 Nodulin-like Serinc PF03348.15 EMC96430.1 - 7.9e-161 535.8 1.7 9e-161 535.6 1.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Na_Pi_cotrans PF02690.15 EMC96430.1 - 0.031 14.4 5.1 0.42 10.7 0.6 3.0 2 1 0 2 2 2 0 Na+/Pi-cotransporter Pox_A9 PF04835.12 EMC96430.1 - 0.65 10.2 3.2 6.2 7.0 0.4 3.6 3 0 0 3 3 3 0 A9 protein conserved region ABC2_membrane_3 PF12698.7 EMC96430.1 - 7.5 5.5 12.9 8 5.5 10.4 2.3 2 1 1 3 3 3 0 ABC-2 family transporter protein TPP_enzyme_N PF02776.18 EMC96431.1 - 9.3e-39 132.8 0.0 3.4e-37 127.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMC96431.1 - 3.6e-17 62.6 0.1 6.4e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMC96431.1 - 8.6e-11 41.7 0.0 2.6e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CMD PF02627.20 EMC96432.1 - 5.1e-21 74.5 0.1 9.2e-21 73.7 0.1 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DSPc PF00782.20 EMC96433.1 - 4.1e-10 39.6 0.0 8.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMC96433.1 - 1.8e-05 24.5 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EMC96433.1 - 0.0036 17.0 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EMC96433.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EMC96433.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate DSPn PF14671.6 EMC96433.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PGAP1 PF07819.13 EMC96434.1 - 7.9e-89 297.3 0.0 1.2e-88 296.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EMC96434.1 - 2.6e-06 28.2 0.2 8.2e-06 26.6 0.2 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC96434.1 - 0.00024 20.8 0.1 0.00076 19.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 EMC96434.1 - 0.0019 18.1 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EMC96434.1 - 0.0051 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EMC96434.1 - 0.008 15.7 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 EMC96434.1 - 0.0083 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Peptidase_M78 PF06114.13 EMC96434.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 IrrE N-terminal-like domain SCPU PF05229.15 EMC96434.1 - 0.16 12.4 0.0 0.49 10.8 0.0 1.8 2 0 0 2 2 2 0 Spore Coat Protein U domain Abhydrolase_5 PF12695.7 EMC96434.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family ResIII PF04851.15 EMC96435.1 - 5.8e-25 88.3 0.0 1.4e-23 83.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMC96435.1 - 5.3e-13 49.3 0.1 5.5e-12 46.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EMC96435.1 - 1.7e-11 44.2 0.0 3.8e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EMC96435.1 - 0.00021 21.1 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EMC96435.1 - 0.0072 16.6 0.1 0.06 13.6 0.0 2.6 2 2 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EMC96435.1 - 0.0072 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 EMC96435.1 - 0.015 14.5 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Transglut_core PF01841.19 EMC96435.1 - 0.047 14.1 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily MIF4G PF02854.19 EMC96436.1 - 4.1e-57 193.2 0.4 1.9e-32 112.7 0.1 3.2 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 EMC96436.1 - 2.2e-39 135.3 4.9 2.2e-39 135.3 4.9 2.4 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Cyclin_N PF00134.23 EMC96438.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain THB PF18362.1 EMC96438.1 - 0.19 11.4 0.4 0.38 10.4 0.4 1.5 1 0 0 1 1 1 0 Tri-helix bundle domain Spc24 PF08286.11 EMC96439.1 - 1.8e-33 114.9 0.1 4.3e-32 110.5 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Angiomotin_C PF12240.8 EMC96439.1 - 0.12 11.9 6.2 0.028 14.0 2.6 1.7 2 0 0 2 2 2 0 Angiomotin C terminal APG6_N PF17675.1 EMC96439.1 - 0.32 11.5 5.6 0.7 10.4 5.8 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Fis1_TPR_C PF14853.6 EMC96440.1 - 2.9e-25 88.1 2.2 4.6e-25 87.4 2.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EMC96440.1 - 5.8e-17 61.1 0.1 1.1e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EMC96440.1 - 0.0016 18.4 1.5 0.0035 17.4 1.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EMC96440.1 - 0.0043 17.5 1.4 0.01 16.4 0.6 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMC96440.1 - 0.082 13.6 0.4 0.38 11.5 0.4 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat CBP_BcsF PF11120.8 EMC96442.1 - 0.033 14.3 0.7 0.097 12.8 0.1 1.9 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsF Mcl1_mid PF12341.8 EMC96447.1 - 2.4e-102 342.3 0.0 7.1e-99 330.9 0.0 2.6 2 0 0 2 2 2 2 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 EMC96447.1 - 2.4e-13 50.2 0.2 0.0026 18.0 0.1 6.4 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMC96447.1 - 1e-09 38.9 6.7 0.0088 16.9 0.2 6.7 8 0 0 8 8 8 2 WD domain, G-beta repeat PD40 PF07676.12 EMC96447.1 - 0.011 15.6 0.0 23 5.1 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EMC96447.1 - 0.057 12.4 0.1 13 4.6 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_pol_alpha_N PF12254.8 EMC96447.1 - 0.061 13.4 2.1 0.14 12.2 2.1 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal zf_UBZ PF18439.1 EMC96447.1 - 0.18 11.5 0.5 0.46 10.1 0.5 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Coatomer_WDAD PF04053.14 EMC96447.1 - 0.24 10.4 0.1 1.6 7.7 0.0 2.2 1 1 1 2 2 2 0 Coatomer WD associated region PQQ_3 PF13570.6 EMC96447.1 - 1 9.9 8.6 0.7 10.5 0.1 4.1 5 0 0 5 5 5 0 PQQ-like domain CHZ PF09649.10 EMC96448.1 - 4e-16 58.2 2.2 4e-16 58.2 2.2 2.8 3 2 0 3 3 3 1 Histone chaperone domain CHZ GATase_2 PF00310.21 EMC96450.1 - 7.9e-179 594.8 0.0 1.1e-178 594.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EMC96450.1 - 5.1e-156 519.4 0.0 8.3e-156 518.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EMC96450.1 - 1.2e-113 379.2 0.0 1.3e-111 372.5 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EMC96450.1 - 9.8e-86 286.2 2.5 1.6e-85 285.5 2.5 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EMC96450.1 - 7e-25 87.8 0.8 4.1e-24 85.3 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EMC96450.1 - 3.2e-21 75.2 0.1 7.3e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 EMC96450.1 - 2e-08 34.7 0.1 2.9e-05 24.5 0.1 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC96450.1 - 2.3e-08 34.1 0.0 7.1e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC96450.1 - 3.4e-07 30.2 4.0 0.0037 16.9 0.2 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EMC96450.1 - 1.1e-06 28.3 0.0 2.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EMC96450.1 - 1.2e-05 24.7 0.2 0.049 12.9 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC96450.1 - 5.3e-05 22.1 0.1 5.3e-05 22.1 0.1 1.8 3 0 0 3 3 3 1 HI0933-like protein FMO-like PF00743.19 EMC96450.1 - 6.5e-05 21.6 0.2 0.012 14.1 0.0 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like FAD_oxidored PF12831.7 EMC96450.1 - 0.00043 19.8 0.0 0.00043 19.8 0.0 1.8 2 0 0 2 2 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMC96450.1 - 0.0011 18.1 0.4 0.0047 16.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 EMC96450.1 - 0.002 18.5 0.1 4.4 7.8 0.1 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EMC96450.1 - 0.0025 17.1 0.1 0.49 9.7 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EMC96450.1 - 0.0038 16.5 0.2 0.014 14.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EMC96450.1 - 0.009 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EMC96450.1 - 0.019 14.1 0.1 0.2 10.7 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein AdoHcyase_NAD PF00670.21 EMC96450.1 - 0.02 15.0 0.2 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.22 EMC96450.1 - 0.024 13.7 0.8 0.094 11.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EMC96450.1 - 0.038 14.0 0.0 0.13 12.3 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 EMC96450.1 - 0.088 12.8 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EMC96450.1 - 0.093 12.1 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMC96450.1 - 0.13 12.1 0.0 0.4 10.5 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_63 PF03200.16 EMC96451.1 - 2.2e-167 557.8 5.9 5.4e-167 556.5 3.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EMC96451.1 - 9.1e-85 284.3 0.1 7.2e-84 281.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EMC96451.1 - 0.00011 21.2 1.6 0.00019 20.4 1.6 1.3 1 0 0 1 1 1 1 Trehalase MMtag PF10159.9 EMC96452.1 - 1e-31 109.1 3.1 1e-31 109.1 3.1 2.6 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Sld7_C PF18596.1 EMC96453.1 - 5.9e-27 93.6 0.0 9.6e-27 92.9 0.0 1.3 1 0 0 1 1 1 1 Sld7 C-terminal domain Sld7_N PF18636.1 EMC96453.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain HLH PF00010.26 EMC96455.1 - 1.3e-12 47.5 0.4 2.5e-12 46.6 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 EMC96455.1 - 0.0056 16.8 2.2 0.018 15.1 2.2 1.8 1 1 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF5333 PF17267.2 EMC96455.1 - 0.013 15.7 0.9 0.031 14.4 0.3 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5333) Pox_A30L_A26L PF06086.12 EMC96455.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein DUF3886 PF13025.6 EMC96455.1 - 0.058 13.6 0.7 0.058 13.6 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3886) DUF2229 PF09989.9 EMC96455.1 - 0.088 12.4 0.9 0.11 12.2 0.9 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) GrpE PF01025.19 EMC96455.1 - 0.49 10.0 4.7 1.4 8.6 4.4 1.8 1 1 0 1 1 1 0 GrpE eIF-6 PF01912.18 EMC96456.1 - 6.6e-80 267.2 0.4 6.6e-80 267.2 0.4 1.5 2 0 0 2 2 2 1 eIF-6 family PUF PF00806.19 EMC96457.1 - 2.8e-62 203.0 6.5 4.9e-09 35.4 0.2 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF842 PF05811.13 EMC96457.1 - 5.7 6.6 8.2 3e+02 1.1 8.2 3.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Fungal_trans PF04082.18 EMC96459.1 - 1.2e-23 83.5 0.7 1.9e-23 82.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC96459.1 - 1.4e-06 28.3 8.6 2.9e-06 27.3 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EMC96460.1 - 1.1e-47 162.1 0.0 1.4e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96460.1 - 4.9e-35 121.2 0.0 6.3e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96460.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMC96460.1 - 2.8e-05 24.1 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC96460.1 - 0.00051 19.6 0.0 0.00076 19.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMC96460.1 - 0.0035 16.5 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Glyco_hydro_125 PF06824.11 EMC96461.1 - 1.8e-181 603.6 0.6 2.1e-181 603.3 0.6 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DAO PF01266.24 EMC96464.1 - 1.6e-58 199.0 3.3 2.5e-58 198.4 3.3 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC96464.1 - 1.6e-05 25.0 0.1 5e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 EMC96464.1 - 0.00019 20.4 0.0 0.017 14.0 0.1 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox PF00070.27 EMC96464.1 - 0.00039 20.9 0.0 0.02 15.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC96464.1 - 0.00049 19.4 0.2 0.056 12.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC96464.1 - 0.001 18.3 1.0 0.0042 16.2 1.0 1.8 1 1 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 EMC96464.1 - 0.025 14.0 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Trp_halogenase PF04820.14 EMC96464.1 - 0.029 13.2 0.5 0.06 12.2 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Actin PF00022.19 EMC96465.1 - 2.2e-150 500.8 0.0 8.8e-150 498.8 0.0 1.7 1 1 0 1 1 1 1 Actin HEAT_2 PF13646.6 EMC96466.1 - 2.3e-08 34.3 0.5 3.2e-08 33.8 0.4 1.3 1 1 0 1 1 1 1 HEAT repeats Arm PF00514.23 EMC96466.1 - 9.6e-07 28.6 0.5 0.032 14.3 0.0 2.3 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EMC96466.1 - 4.7e-06 26.4 0.8 0.15 12.4 0.1 2.5 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 EMC96466.1 - 9e-06 26.1 0.8 6.7e-05 23.3 0.6 2.3 1 1 1 2 2 2 2 HEAT-like repeat Atx10homo_assoc PF09759.9 EMC96466.1 - 0.029 14.4 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Ligase_CoA PF00549.19 EMC96466.1 - 0.046 13.5 0.1 0.068 13.0 0.1 1.2 1 0 0 1 1 1 0 CoA-ligase LPP20 PF02169.16 EMC96466.1 - 0.047 14.0 0.0 0.052 13.9 0.0 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein Glyco_hydro_28 PF00295.17 EMC96468.1 - 7.9e-34 117.2 14.1 4e-23 82.0 4.4 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 28 C1_2 PF03107.16 EMC96469.1 - 0.014 15.7 9.0 0.018 15.3 9.0 1.2 1 0 0 1 1 1 0 C1 domain zf-HIT PF04438.16 EMC96469.1 - 0.02 14.8 7.0 0.041 13.8 7.0 1.6 1 1 0 1 1 1 0 HIT zinc finger C1_1 PF00130.22 EMC96469.1 - 0.075 12.9 10.0 0.12 12.2 0.8 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) p450 PF00067.22 EMC96471.1 - 9.1e-60 202.7 0.0 1.2e-59 202.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rick_17kDa_Anti PF05433.15 EMC96473.1 - 0.0034 17.2 17.3 0.0069 16.2 17.3 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 EMC96473.1 - 0.26 11.1 12.4 0.45 10.3 12.4 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper TraT PF05818.12 EMC96473.1 - 0.36 10.5 1.9 0.52 10.0 1.9 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein PT-VENN PF04829.13 EMC96473.1 - 8.4 6.6 7.0 14 5.8 7.0 1.2 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif TatD_DNase PF01026.21 EMC96474.1 - 1.2e-21 77.3 0.0 1.9e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase SPATA3 PF15662.5 EMC96476.1 - 0.66 10.6 11.4 0.49 11.0 1.0 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family DUF883 PF05957.13 EMC96477.1 - 0.87 10.2 5.8 1.4 9.5 4.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mo-co_dimer PF03404.16 EMC96478.1 - 3.7e-60 201.9 0.1 7.1e-60 201.0 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EMC96478.1 - 2.5e-54 183.5 0.0 4.3e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 EMC96478.1 - 3.1e-35 120.5 0.0 5.5e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EMC96478.1 - 5.7e-28 97.7 0.0 1.2e-27 96.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EMC96478.1 - 1.1e-20 73.6 0.1 2.5e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EMC96478.1 - 5.6e-05 23.3 0.1 0.0066 16.6 0.0 2.5 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 EMC96479.1 - 5.6e-45 153.8 0.2 9.5e-45 153.1 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EMC96479.1 - 9.5e-20 70.7 0.0 1.7e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.6 EMC96479.1 - 4.7e-17 61.8 0.0 1.4e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.27 EMC96479.1 - 1.2e-16 61.0 4.8 1.6e-15 57.4 0.5 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EMC96479.1 - 3.8e-15 55.6 0.1 2.1e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Fer2_BFD PF04324.15 EMC96479.1 - 1.3e-13 51.0 7.2 4.3e-11 43.0 4.7 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 EMC96479.1 - 1e-10 41.3 0.0 2.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.6 EMC96479.1 - 2.5e-06 27.0 0.0 4.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMC96479.1 - 3.3e-06 26.7 0.2 0.039 13.3 0.0 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Rubredoxin_C PF18267.1 EMC96479.1 - 1.7e-05 24.7 0.0 0.046 13.6 0.0 3.1 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 EMC96479.1 - 5.7e-05 23.1 0.3 1.1 9.2 0.0 3.4 2 1 1 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 EMC96479.1 - 0.015 14.5 0.0 0.082 12.0 0.0 2.0 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EMC96479.1 - 0.027 13.2 0.0 2.6 6.7 0.0 3.2 3 1 1 4 4 4 0 HI0933-like protein Glu_dehyd_C PF16912.5 EMC96479.1 - 0.24 10.9 0.5 19 4.7 0.1 2.9 2 1 1 3 3 3 0 Glucose dehydrogenase C-terminus SOG2 PF10428.9 EMC96480.1 - 9.5 5.3 14.2 11 5.0 14.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mit_KHE1 PF10173.9 EMC96481.1 - 4e-61 206.4 0.1 4e-61 206.4 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Tyrosinase PF00264.20 EMC96482.1 - 1e-52 179.7 5.9 1.5e-52 179.1 5.9 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Cutinase PF01083.22 EMC96483.1 - 4.2e-46 157.1 5.8 5e-46 156.9 5.8 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EMC96483.1 - 0.00038 20.1 0.5 0.00051 19.7 0.5 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 EMC96485.1 - 6.1e-21 75.2 0.0 3.4e-18 66.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC96485.1 - 3.6e-13 50.6 0.5 2.8e-12 47.7 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC96485.1 - 8.7e-13 48.1 0.0 3.7e-12 46.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 EMC96485.1 - 5.4e-06 25.9 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EMC96485.1 - 1.7e-05 24.6 0.0 5.3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Chlorophyllase2 PF12740.7 EMC96485.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 EMC96485.1 - 0.019 14.6 0.0 0.098 12.2 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 EMC96485.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Spo7 PF03907.13 EMC96486.1 - 4.3e-83 278.1 0.0 6.3e-83 277.6 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein MFS_1 PF07690.16 EMC96487.1 - 5.4e-35 120.9 35.5 8.5e-35 120.3 35.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SRP68 PF16969.5 EMC96488.1 - 9.3e-189 629.0 12.0 1.1e-188 628.8 12.0 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PMEI PF04043.15 EMC96488.1 - 4.7 7.5 8.9 0.32 11.3 0.6 3.0 3 1 1 4 4 4 0 Plant invertase/pectin methylesterase inhibitor PQQ_2 PF13360.6 EMC96489.1 - 0.0014 18.3 0.0 0.018 14.6 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 EMC96489.1 - 0.0042 17.5 0.5 2.4 8.8 0.0 3.5 3 1 0 3 3 3 2 PQQ-like domain Metallophos PF00149.28 EMC96490.1 - 2.5e-11 44.4 0.1 4.9e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5353 PF17304.2 EMC96492.1 - 7.4e-36 121.7 4.0 1.1e-35 121.2 4.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Apolipoprotein PF01442.18 EMC96492.1 - 0.00047 20.1 14.7 0.00061 19.7 14.7 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2207 PF09972.9 EMC96492.1 - 0.0012 17.7 0.1 0.0015 17.4 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TAtT PF16811.5 EMC96492.1 - 0.0078 15.5 4.0 0.0098 15.2 4.0 1.2 1 0 0 1 1 1 1 TRAP transporter T-component Macoilin PF09726.9 EMC96492.1 - 0.025 13.2 12.8 0.031 12.9 12.8 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 EMC96492.1 - 0.097 11.3 2.7 0.1 11.2 2.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EMC96492.1 - 0.22 10.2 9.5 0.26 10.0 9.5 1.2 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 EMC96492.1 - 0.33 10.5 9.2 0.4 10.2 9.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4553 PF15090.6 EMC96492.1 - 0.39 9.7 18.8 0.46 9.4 18.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) DUF417 PF04224.12 EMC96492.1 - 0.68 9.5 2.0 0.38 10.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF417 Borrelia_P83 PF05262.11 EMC96492.1 - 1.6 7.1 25.4 2 6.8 25.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.19 EMC96492.1 - 2.2 6.1 8.9 2.5 5.9 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCU PF04678.13 EMC96492.1 - 5.6 7.0 11.8 3.5 7.7 2.8 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter VSG_B PF13206.6 EMC96492.1 - 7.7 5.7 18.4 10 5.3 18.4 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain ATP-synt_B PF00430.18 EMC96492.1 - 8 6.6 27.6 15 5.7 16.5 2.2 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Peptidase_C12 PF01088.21 EMC96493.1 - 2.9e-57 193.8 0.0 4.2e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EMC96493.1 - 1.2e-09 37.9 0.1 1.2e-09 37.9 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases DUF1180 PF06679.12 EMC96494.1 - 0.21 12.0 0.9 0.47 10.9 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 EMC96494.1 - 0.34 11.8 1.2 1.7 9.5 0.0 2.6 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Trp_oprn_chp PF09534.10 EMC96494.1 - 0.39 10.5 3.5 0.21 11.3 0.4 2.0 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4064 PF13273.6 EMC96494.1 - 4.7 7.5 14.0 0.072 13.4 4.2 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) SLATT_3 PF18184.1 EMC96494.1 - 6.1 7.0 5.3 11 6.1 0.2 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 CT_C_D PF02682.16 EMC96495.1 - 0.04 13.6 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Sugar_tr PF00083.24 EMC96496.1 - 7.8e-76 255.8 23.9 9.2e-76 255.5 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC96496.1 - 2.6e-13 49.6 24.3 2.6e-13 49.6 24.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DPM3 PF08285.11 EMC96496.1 - 0.31 11.3 0.0 0.31 11.3 0.0 3.3 6 0 0 6 6 6 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1090 PF06476.12 EMC96497.1 - 0.042 14.0 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) CUE PF02845.16 EMC96497.1 - 0.052 13.3 0.1 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 CUE domain Yip1 PF04893.17 EMC96498.1 - 4.5e-11 42.8 18.1 6.9e-11 42.2 18.1 1.4 1 1 0 1 1 1 1 Yip1 domain GTP_EFTU PF00009.27 EMC96499.1 - 1.1e-34 119.6 0.0 1.4e-33 116.1 0.0 3.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EMC96499.1 - 6.3e-21 74.5 0.0 1.8e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EMC96499.1 - 2e-09 37.7 5.3 2.5e-08 34.2 0.4 3.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EMC96499.1 - 2.5e-09 36.9 0.2 1.2e-08 34.7 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EMC96499.1 - 6.2e-07 29.5 0.8 3.6e-06 27.0 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EMC96499.1 - 0.00064 19.9 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EMC96499.1 - 0.0094 15.8 0.1 0.049 13.4 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DSPc PF00782.20 EMC96502.1 - 1.6e-09 37.7 0.0 2.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EMC96502.1 - 0.00015 22.1 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EMC96502.1 - 0.042 13.4 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase FMN_red PF03358.15 EMC96502.1 - 0.1 12.3 0.2 0.51 10.1 0.0 1.9 1 1 0 2 2 2 0 NADPH-dependent FMN reductase SecY PF00344.20 EMC96504.1 - 1.1e-70 238.4 8.1 1.4e-70 238.0 8.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EMC96504.1 - 1.9e-17 62.8 0.2 5.4e-17 61.3 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Ribosomal_L3 PF00297.22 EMC96505.1 - 1.6e-183 609.8 10.5 1.8e-183 609.6 10.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TetR_C_22 PF17928.1 EMC96506.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3827 PF12877.7 EMC96506.1 - 0.6 8.4 7.3 0.8 8.0 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) V_ATPase_I PF01496.19 EMC96506.1 - 2.4 6.0 3.8 3.3 5.5 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 EMC96506.1 - 2.6 7.6 21.9 0.25 10.9 16.7 1.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 EMC96506.1 - 3.8 6.8 7.6 5.2 6.3 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4778 PF16008.5 EMC96506.1 - 5 7.1 8.7 7.1 6.6 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Hpt PF01627.23 EMC96507.1 - 1e-11 44.9 0.5 2.6e-11 43.6 0.5 1.7 1 1 0 1 1 1 1 Hpt domain Aminotran_1_2 PF00155.21 EMC96510.1 - 3.1e-90 303.0 0.0 3.6e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II BING4CT PF08149.11 EMC96511.1 - 7.8e-40 134.6 0.0 1.2e-35 121.1 0.0 3.2 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EMC96511.1 - 4.4e-09 36.5 0.3 2.2 8.6 0.1 6.0 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMC96511.1 - 0.00029 21.6 0.0 1.6 9.8 0.0 5.1 5 1 1 6 6 6 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EMC96511.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region DUF1974 PF09317.11 EMC96511.1 - 0.16 11.5 2.7 0.26 10.8 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Sulfate_transp PF00916.20 EMC96512.1 - 1.6e-81 274.0 11.4 1.8e-80 270.6 11.4 2.0 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EMC96512.1 - 1.1e-15 57.2 0.0 2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EMC96512.1 - 0.0016 18.7 0.0 0.0044 17.3 0.0 1.8 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EMC96512.1 - 0.28 11.6 9.1 0.033 14.6 1.4 2.5 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily End3 PF12761.7 EMC96513.1 - 3.1e-77 259.3 2.9 4.2e-77 258.8 2.9 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EMC96513.1 - 3.8e-46 155.3 0.0 2.8e-45 152.6 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EMC96513.1 - 4.4e-08 32.1 0.6 3.1e-07 29.5 0.2 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EMC96513.1 - 3.6e-06 26.7 0.1 2.2e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 EMC96513.1 - 3.1e-05 24.3 0.1 0.00013 22.3 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EMC96513.1 - 0.00012 21.7 1.4 0.0019 18.0 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 EMC96513.1 - 0.00068 19.0 0.3 0.0029 17.0 0.1 2.2 2 0 0 2 2 2 1 EF hand CSN5_C PF18323.1 EMC96513.1 - 0.51 11.3 3.7 1.4 9.8 2.5 2.3 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF4140 PF13600.6 EMC96513.1 - 0.94 10.0 5.9 7.2 7.1 0.1 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF16 PF01519.16 EMC96513.1 - 3.9 8.0 6.2 1.6 9.2 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 FliJ PF02050.16 EMC96513.1 - 3.9 7.7 12.1 0.13 12.5 2.5 2.6 2 1 1 3 3 3 0 Flagellar FliJ protein UPF0242 PF06785.11 EMC96513.1 - 5.3 7.1 7.8 8.9 6.4 7.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EMC96513.1 - 5.9 7.6 10.6 9.7 6.9 0.8 2.9 2 1 1 3 3 3 0 SlyX Csm1_N PF18504.1 EMC96513.1 - 7.5 7.0 8.8 8.2 6.9 0.9 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain Swi5 PF07061.11 EMC96513.1 - 8 6.6 6.5 15 5.7 1.1 2.4 2 0 0 2 2 2 0 Swi5 Prefoldin_2 PF01920.20 EMC96513.1 - 8.4 6.4 9.4 5 7.1 0.6 2.7 2 1 1 3 3 3 0 Prefoldin subunit Thiolase_N PF00108.23 EMC96514.1 - 1.1e-68 231.4 0.1 1.5e-68 231.0 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMC96514.1 - 2.7e-41 140.0 0.3 7.2e-41 138.7 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMC96514.1 - 0.0081 15.8 1.6 0.018 14.6 0.7 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EMC96514.1 - 0.0091 15.8 0.1 2.6 8.0 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Skp1_POZ PF03931.15 EMC96514.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF348 PF03990.14 EMC96514.1 - 0.81 9.5 3.0 7.2 6.4 0.1 2.9 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain Cupin_2 PF07883.11 EMC96515.1 - 0.08 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Cupin domain AcetylCoA_hydro PF02550.15 EMC96516.1 - 1.9e-50 171.6 0.0 2.8e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EMC96516.1 - 5e-43 146.7 0.0 8.5e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF1772 PF08592.11 EMC96517.1 - 4.6e-18 65.8 0.2 7e-18 65.3 0.1 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF3180 PF11377.8 EMC96517.1 - 0.022 14.9 1.4 2.8 8.1 0.1 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3180) Fungal_trans PF04082.18 EMC96518.1 - 4.9e-13 48.7 1.3 6.5e-13 48.3 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC96518.1 - 5.8e-07 29.5 16.0 1.2e-06 28.5 16.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EMC96519.1 - 9.2e-22 77.4 0.0 1.5e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96519.1 - 5.5e-18 65.4 0.0 8.1e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96519.1 - 0.0065 16.4 0.0 0.018 14.9 0.0 1.8 2 1 0 2 2 2 1 KR domain Chorismate_bind PF00425.18 EMC96520.1 - 3.5e-77 259.4 0.0 5e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EMC96520.1 - 4.5e-28 98.3 0.0 6.8e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EMC96520.1 - 6.3e-17 62.1 0.0 1.8e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EMC96520.1 - 1.7e-06 27.9 0.0 7.4e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 Longin PF13774.6 EMC96521.1 - 2.7e-20 72.2 0.2 4.5e-20 71.5 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EMC96521.1 - 5e-16 58.3 0.2 1.4e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Synaptobrevin Sirohm_synth_C PF14823.6 EMC96521.1 - 0.013 15.1 1.0 3.1 7.5 0.0 2.7 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal DUF4404 PF14357.6 EMC96521.1 - 0.048 14.3 0.5 2.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ASXH PF13919.6 EMC96522.1 - 2.8e-15 56.6 1.8 3.5e-15 56.2 1.8 1.1 1 0 0 1 1 1 1 Asx homology domain Elong_Iki1 PF10483.9 EMC96523.1 - 2.1e-103 345.9 0.0 2.5e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Med6 PF04934.14 EMC96524.1 - 2.1e-26 92.3 0.0 3.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Fungal_trans PF04082.18 EMC96525.1 - 1.8e-06 27.2 0.1 6.8e-06 25.3 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.31 EMC96526.1 - 2.6e-06 27.6 0.0 5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF1981 PF09324.10 EMC96526.1 - 0.049 13.5 0.0 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) RF-1 PF00472.20 EMC96528.1 - 2.2e-25 88.9 4.1 2.5e-25 88.6 4.1 1.0 1 0 0 1 1 1 1 RF-1 domain SPT_ssu-like PF11779.8 EMC96529.1 - 1.7e-16 59.5 1.4 1.7e-16 59.5 1.4 1.9 2 0 0 2 2 2 1 Small subunit of serine palmitoyltransferase-like CRT10 PF08728.10 EMC96530.1 - 2.9e-13 48.9 0.0 2.1e-08 32.9 0.0 2.5 2 1 0 2 2 2 2 CRT10 NmrA PF05368.13 EMC96534.1 - 3.6e-30 105.2 0.0 5.2e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC96534.1 - 1.2e-07 31.8 0.0 5.5e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC96534.1 - 8.6e-05 22.1 0.0 0.03 13.8 0.0 2.4 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 EMC96534.1 - 0.043 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 EMC96534.1 - 0.088 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Med2 PF11214.8 EMC96537.1 - 0.025 14.8 1.2 0.035 14.3 1.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF1640 PF07798.11 EMC96538.1 - 3.2e-43 147.8 6.7 3.2e-43 147.8 6.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 EMC96538.1 - 0.37 10.1 4.9 0.12 11.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MPS2 PF17060.5 EMC96539.1 - 0.0014 18.0 1.6 0.0015 17.8 1.6 1.0 1 0 0 1 1 1 1 Monopolar spindle protein 2 HALZ PF02183.18 EMC96539.1 - 0.0035 17.5 5.8 0.0064 16.7 2.2 2.8 2 2 1 3 3 3 1 Homeobox associated leucine zipper FAM76 PF16046.5 EMC96539.1 - 0.0043 16.4 0.1 0.0045 16.4 0.1 1.1 1 0 0 1 1 1 1 FAM76 protein Tho2 PF11262.8 EMC96539.1 - 0.0066 15.7 0.9 0.0079 15.4 0.9 1.0 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 LRRFIP PF09738.9 EMC96539.1 - 0.014 14.9 1.4 0.018 14.6 1.4 1.0 1 0 0 1 1 1 0 LRRFIP family GrpE PF01025.19 EMC96539.1 - 0.035 13.8 0.4 0.039 13.6 0.4 1.2 1 0 0 1 1 1 0 GrpE DUF5082 PF16888.5 EMC96539.1 - 0.053 13.8 0.8 0.35 11.2 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Imm70 PF15601.6 EMC96539.1 - 0.16 11.5 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 70 HSP70 PF00012.20 EMC96540.1 - 1.1e-259 862.7 7.2 1.3e-259 862.5 7.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMC96540.1 - 1.2e-16 60.5 0.1 9.4e-16 57.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EMC96540.1 - 0.0032 17.2 0.0 0.0088 15.8 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EMC96540.1 - 0.017 15.5 4.4 6.5 7.2 0.2 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 EMC96540.1 - 0.018 14.3 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Mso1_Sec1_bdg PF14475.6 EMC96541.1 - 5.6e-20 70.7 0.1 1e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 FAD_binding_2 PF00890.24 EMC96542.1 - 1.1e-33 117.0 0.0 1.5e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain LPD22 PF18834.1 EMC96542.1 - 0.0086 16.3 0.0 0.34 11.1 0.0 2.2 2 0 0 2 2 2 1 Large polyvalent protein associated domain 22 Pyr_redox_2 PF07992.14 EMC96542.1 - 0.027 13.7 0.0 0.18 11.0 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC96542.1 - 0.058 14.0 0.2 25 5.5 0.0 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMC96542.1 - 0.11 11.6 0.0 8.8 5.3 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Sigma70_r3 PF04539.16 EMC96542.1 - 0.16 12.1 0.1 0.42 10.7 0.1 1.7 2 0 0 2 2 2 0 Sigma-70 region 3 IF2_N PF04760.15 EMC96542.1 - 0.18 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_Mga PF08280.11 EMC96542.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain 2-Hacid_dh_C PF02826.19 EMC96545.1 - 5.2e-49 166.0 0.0 1.1e-48 164.9 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMC96545.1 - 2.5e-16 59.5 0.0 3.9e-16 58.9 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMC96545.1 - 0.00013 22.2 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrmE_N PF10396.9 EMC96546.1 - 5.9e-36 123.3 0.0 1.3e-35 122.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EMC96546.1 - 2.2e-32 112.9 0.4 3.3e-32 112.3 0.4 1.3 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EMC96546.1 - 2.2e-17 63.2 0.0 3.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMC96546.1 - 9.3e-06 25.3 0.1 5.6e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EMC96546.1 - 2.9e-05 24.2 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 EMC96546.1 - 0.0013 18.7 0.1 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 EMC96546.1 - 0.025 14.8 0.1 0.82 9.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CorA PF01544.18 EMC96546.1 - 0.05 12.9 1.2 0.085 12.2 1.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FH2 PF02181.23 EMC96547.1 - 9.4e-85 285.0 7.2 9.4e-85 285.0 7.2 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EMC96547.1 - 1.9e-64 216.7 0.1 7.4e-64 214.8 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EMC96547.1 - 3.4e-49 167.1 0.2 3.4e-49 167.1 0.2 3.8 3 1 1 4 4 4 1 Diaphanous FH3 Domain Nrap_D6 PF17407.2 EMC96547.1 - 0.025 14.8 1.8 0.38 11.0 0.2 3.2 4 0 0 4 4 4 0 Nrap protein domain 6 Gp-FAR-1 PF05823.12 EMC96547.1 - 0.4 11.0 5.3 0.08 13.3 0.4 2.4 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4065 PF13274.6 EMC96547.1 - 0.98 10.3 6.2 0.93 10.4 0.4 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF4065) Hus1 PF04005.12 EMC96548.1 - 3.6e-94 315.2 0.0 4e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein F-box-like PF12937.7 EMC96549.1 - 0.03 14.2 0.2 0.03 14.2 0.2 2.0 2 0 0 2 2 2 0 F-box-like Ribosomal_60s PF00428.19 EMC96549.1 - 0.043 14.4 2.4 0.13 12.9 2.4 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box PF00646.33 EMC96549.1 - 0.048 13.6 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 F-box domain FAM176 PF14851.6 EMC96549.1 - 1.7 8.3 8.5 0.89 9.2 2.6 2.4 2 0 0 2 2 2 0 FAM176 family Mito_carr PF00153.27 EMC96550.1 - 1.2e-59 198.3 3.0 2.9e-20 72.0 0.4 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein HEAT_2 PF13646.6 EMC96551.1 - 1.7e-14 54.0 10.8 0.0029 18.0 0.1 7.3 5 1 1 6 6 6 4 HEAT repeats Cnd1 PF12717.7 EMC96551.1 - 1.5e-05 25.1 0.1 0.33 11.0 0.0 4.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EMC96551.1 - 0.0002 21.9 0.0 0.12 13.0 0.0 4.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EMC96551.1 - 0.0088 16.5 18.3 2.6 8.7 0.1 7.6 7 0 0 7 7 7 1 HEAT-like repeat HEAT PF02985.22 EMC96551.1 - 0.018 15.2 36.9 0.13 12.5 0.1 11.4 14 0 0 14 14 14 0 HEAT repeat Arm PF00514.23 EMC96551.1 - 0.056 13.5 6.9 0.71 10.0 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2019 PF09450.10 EMC96551.1 - 0.073 13.0 1.2 2.5 8.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) DUF4042 PF13251.6 EMC96551.1 - 0.21 11.3 4.9 0.29 10.8 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) RICTOR_M PF14666.6 EMC96551.1 - 0.28 11.0 1.5 57 3.6 0.0 4.6 6 0 0 6 6 6 0 Rapamycin-insensitive companion of mTOR, middle domain UNC45-central PF11701.8 EMC96551.1 - 2.8 7.9 5.7 55 3.7 0.0 4.7 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central EF-hand_4 PF12763.7 EMC96552.1 - 4e-38 129.5 0.0 1e-15 57.5 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EMC96552.1 - 2.8e-08 34.1 0.0 0.0043 17.5 0.1 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EMC96552.1 - 5.8e-07 28.6 0.1 0.65 9.7 0.0 4.8 5 0 0 5 5 5 2 EF hand Macoilin PF09726.9 EMC96552.1 - 0.00072 18.2 14.9 0.0013 17.5 14.9 1.3 1 0 0 1 1 1 1 Macoilin family EF-hand_8 PF13833.6 EMC96552.1 - 0.0057 16.5 0.0 7.1 6.6 0.0 3.8 4 0 0 4 4 3 0 EF-hand domain pair Rab5-bind PF09311.11 EMC96552.1 - 0.014 14.8 17.9 0.027 13.8 17.9 1.5 1 0 0 1 1 1 0 Rabaptin-like protein DUF1192 PF06698.11 EMC96552.1 - 0.046 13.8 0.2 0.046 13.8 0.2 2.8 3 0 0 3 3 1 0 Protein of unknown function (DUF1192) Tup_N PF08581.10 EMC96552.1 - 0.06 13.7 16.1 0.07 13.4 4.7 2.8 1 1 1 2 2 2 0 Tup N-terminal TPR_MLP1_2 PF07926.12 EMC96552.1 - 0.065 13.3 32.7 0.31 11.1 17.9 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 EMC96552.1 - 0.1 11.8 25.8 0.0071 15.6 19.0 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region EzrA PF06160.12 EMC96552.1 - 0.15 10.2 15.5 0.23 9.6 15.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ATG16 PF08614.11 EMC96552.1 - 0.16 12.2 41.0 0.16 12.2 21.2 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FPP PF05911.11 EMC96552.1 - 0.17 10.1 21.6 0.24 9.5 21.6 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 EMC96552.1 - 0.17 10.8 32.1 0.1 11.5 17.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 EMC96552.1 - 0.29 10.1 18.1 0.47 9.4 18.1 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ADIP PF11559.8 EMC96552.1 - 0.35 11.0 31.4 0.25 11.4 14.2 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 EMC96552.1 - 0.58 10.2 29.2 0.024 14.6 9.4 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 EMC96552.1 - 0.67 9.5 27.1 0.87 9.1 10.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF724 PF05266.14 EMC96552.1 - 0.68 9.7 19.4 0.02 14.7 6.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Occludin_ELL PF07303.13 EMC96552.1 - 0.73 10.6 9.5 0.16 12.7 4.7 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF4200 PF13863.6 EMC96552.1 - 0.8 10.1 22.3 1.2 9.5 15.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.6 EMC96552.1 - 0.83 9.0 28.3 0.68 9.3 13.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LPP PF04728.13 EMC96552.1 - 1.1 9.6 13.4 1.6 9.2 1.0 3.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper 4HB_MCP_1 PF12729.7 EMC96552.1 - 1.2 8.6 10.6 0.088 12.3 3.0 2.6 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction DUF1664 PF07889.12 EMC96552.1 - 1.3 9.1 13.8 2.5 8.2 5.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 EMC96552.1 - 1.4 7.5 17.3 0.98 8.0 3.1 2.1 1 1 1 2 2 2 0 AAA domain APG6_N PF17675.1 EMC96552.1 - 2.3 8.8 36.9 0.6 10.6 13.2 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region MAD PF05557.13 EMC96552.1 - 2.8 6.2 27.6 4.2 5.6 27.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein V_ATPase_I PF01496.19 EMC96552.1 - 2.9 5.7 15.2 1.2 6.9 13.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family JAKMIP_CC3 PF16034.5 EMC96552.1 - 4 7.3 26.5 16 5.4 26.5 2.1 1 1 0 1 1 1 0 JAKMIP CC3 domain YabA PF06156.13 EMC96552.1 - 4.6 7.9 19.3 5.3 7.7 5.8 2.5 1 1 0 2 2 2 0 Initiation control protein YabA DUF919 PF06034.11 EMC96552.1 - 8.1 6.4 6.0 1 9.2 0.0 2.5 3 1 1 4 4 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) MFS_1 PF07690.16 EMC96554.1 - 2.8e-35 121.9 33.6 2.8e-35 121.9 33.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC96554.1 - 7.3e-12 44.9 10.6 7.3e-12 44.9 10.6 3.1 3 1 1 4 4 4 1 Sugar (and other) transporter DUF1833 PF08875.11 EMC96554.1 - 0.22 11.0 0.3 0.34 10.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) Pkinase PF00069.25 EMC96556.1 - 3.3e-50 170.9 0.0 4.9e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC96556.1 - 2.8e-28 98.9 0.0 4.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC96556.1 - 3.5e-10 39.7 0.0 4.6e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DUF918 PF06033.11 EMC96556.1 - 0.0063 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF918) Kdo PF06293.14 EMC96556.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMC96556.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family UCH PF00443.29 EMC96557.1 - 5.2e-30 104.8 0.0 9.7e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC96557.1 - 3.6e-14 53.1 0.0 8.6e-14 51.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_3_C PF01915.22 EMC96559.1 - 7.2e-44 150.2 0.0 1.2e-43 149.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMC96559.1 - 2.4e-36 125.7 0.0 4.5e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMC96559.1 - 1.4e-14 54.0 0.1 2.6e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Rhodanese PF00581.20 EMC96560.1 - 2e-19 70.1 0.0 2.3e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain RlmM_FDX PF18125.1 EMC96560.1 - 0.071 13.6 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 RlmM ferredoxin-like domain EIF_2_alpha PF07541.12 EMC96561.1 - 3.2e-37 127.2 0.0 6e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EMC96561.1 - 1.4e-13 51.0 0.7 2.7e-13 50.0 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Cellulase PF00150.18 EMC96562.1 - 3.4e-29 102.1 3.6 6.1e-29 101.3 3.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.13 EMC96563.1 - 3.5e-44 151.2 0.1 5.5e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC96563.1 - 3.8e-14 52.5 0.0 9.1e-14 51.2 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 EMC96563.1 - 0.00034 20.4 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC96563.1 - 0.00035 20.1 0.1 0.0006 19.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EMC96563.1 - 0.0062 15.3 0.0 0.24 10.1 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EMC96563.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 EMC96563.1 - 0.077 12.6 0.0 4.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Lipase_3 PF01764.25 EMC96563.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) GNVR PF13807.6 EMC96564.1 - 0.02 14.8 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase UIM PF02809.20 EMC96564.1 - 0.12 12.3 10.8 1.1 9.4 2.2 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif MutL_C PF08676.11 EMC96566.1 - 1.4e-26 93.0 0.2 2.8e-26 92.0 0.2 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EMC96566.1 - 3.4e-20 71.9 0.0 1.2e-19 70.1 0.0 2.0 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EMC96566.1 - 3.7e-12 46.2 0.2 1.8e-11 44.0 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EMC96566.1 - 6.3e-06 26.7 0.0 1.6e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SWIRM PF04433.17 EMC96568.1 - 3.2e-10 40.2 0.1 1.2e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain PMT PF02366.18 EMC96569.1 - 3.4e-88 295.3 14.9 3.4e-88 295.3 14.9 1.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMC96569.1 - 8.2e-64 214.9 19.3 8.2e-64 214.9 19.3 2.3 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMC96569.1 - 1.8e-34 119.2 2.5 3e-34 118.5 2.5 1.2 1 0 0 1 1 1 1 MIR domain DUF5071 PF16804.5 EMC96569.1 - 0.028 14.7 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) Atg8 PF02991.16 EMC96570.1 - 2.7e-51 172.1 0.2 3.2e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EMC96570.1 - 3e-06 27.5 0.0 3.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 NCE101 PF11654.8 EMC96571.1 - 2e-06 27.4 0.0 3.3e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Non-classical export protein 1 Thioredoxin PF00085.20 EMC96573.1 - 2.1e-07 30.8 0.0 2.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMC96573.1 - 0.0073 16.7 0.0 0.031 14.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMC96573.1 - 0.0085 16.4 0.0 0.68 10.3 0.0 2.2 1 1 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 EMC96573.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.6 EMC96573.1 - 0.051 13.6 0.0 0.32 11.1 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin domain RcnB PF11776.8 EMC96574.1 - 0.18 11.9 0.7 24 5.1 0.0 2.4 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator DUF5572 PF17733.1 EMC96576.1 - 2.4e-22 78.5 1.2 3.3e-22 78.1 1.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5572) LSM14 PF12701.7 EMC96577.1 - 7e-29 99.8 0.1 9.6e-29 99.3 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EMC96577.1 - 1.9e-05 24.7 0.0 2.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 EMC96577.1 - 0.022 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 LSM domain Mucin PF01456.17 EMC96578.1 - 0.7 9.9 18.7 1.1 9.3 18.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 EMC96578.1 - 9.1 6.7 8.9 15 6.0 8.9 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SET PF00856.28 EMC96581.1 - 8.9e-18 65.2 5.3 1.6e-17 64.4 0.2 3.4 3 1 0 3 3 3 1 SET domain SRI PF08236.11 EMC96581.1 - 1.9e-17 63.2 13.4 3.1e-17 62.5 12.2 2.1 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 EMC96581.1 - 5e-10 39.3 8.4 5e-10 39.3 8.4 2.2 3 0 0 3 3 3 1 AWS domain Med26 PF08711.11 EMC96581.1 - 2e-07 30.9 2.5 2.3e-07 30.7 0.8 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.26 EMC96581.1 - 4.2e-07 29.9 0.4 9.4e-07 28.8 0.4 1.7 1 0 0 1 1 1 1 WW domain DUF445 PF04286.12 EMC96581.1 - 2.5 7.8 5.8 2.3 7.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF998 PF06197.13 EMC96582.1 - 0.017 14.7 1.6 0.055 13.1 1.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Thioredox_DsbH PF03190.15 EMC96584.1 - 5.6e-69 231.3 0.0 9.7e-69 230.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EMC96584.1 - 9.8e-08 32.1 0.0 2.8e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 EMC96584.1 - 0.0058 15.7 0.1 0.67 9.0 0.0 3.2 2 1 1 3 3 3 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 EMC96584.1 - 0.031 13.8 0.2 0.13 11.8 0.2 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 76 Sigma70_r4_2 PF08281.12 EMC96584.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 CAP PF00188.26 EMC96586.1 - 8e-15 55.8 4.3 8e-15 55.8 4.3 2.3 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Hamartin PF04388.12 EMC96586.1 - 0.33 9.6 23.5 0.36 9.4 23.5 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 EMC96586.1 - 3.7 7.4 17.7 5.1 7.0 17.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 EMC96586.1 - 4.5 6.4 41.1 6 6.0 41.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Suf PF05843.14 EMC96586.1 - 5.4 6.9 9.5 7.9 6.4 9.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4551 PF15087.6 EMC96586.1 - 6.9 5.4 18.5 9 5.0 18.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NIF PF03031.18 EMC96587.1 - 6.8e-25 87.7 0.3 9.5e-25 87.2 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNA_pol_Rpb2_6 PF00562.28 EMC96588.1 - 1.4e-121 406.3 0.2 1.9e-121 405.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EMC96588.1 - 8e-50 169.2 0.1 1.2e-49 168.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EMC96588.1 - 5.2e-32 110.1 1.4 1.5e-31 108.6 1.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EMC96588.1 - 1.2e-28 100.0 0.0 2.7e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EMC96588.1 - 2e-25 88.8 0.5 4.8e-25 87.6 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EMC96588.1 - 3.7e-18 65.4 0.1 7.7e-18 64.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EMC96588.1 - 1.9e-09 37.9 0.3 6.2e-09 36.3 0.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.19 EMC96590.1 - 5e-54 177.1 14.2 3.4e-09 35.9 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EMC96590.1 - 0.03 14.7 0.4 22 5.4 0.0 3.2 2 1 1 3 3 3 0 CPL (NUC119) domain DUF3684 PF12449.8 EMC96591.1 - 0 1409.9 0.0 0 1409.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EMC96591.1 - 0.00023 21.0 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 EMC96591.1 - 0.0029 17.7 2.6 0.076 13.1 0.9 2.4 2 0 0 2 2 2 1 WLM domain CAS_CSE1 PF03378.15 EMC96592.1 - 3e-168 559.9 0.0 5.4e-168 559.1 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EMC96592.1 - 2.8e-146 487.1 1.8 4.5e-146 486.4 1.8 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EMC96592.1 - 4.1e-18 65.1 0.1 1.3e-17 63.5 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain RNA_pol_Rpc4 PF05132.14 EMC96592.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3437 PF11919.8 EMC96592.1 - 0.032 14.1 0.1 1.3 8.9 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) MMS19_N PF14500.6 EMC96592.1 - 0.072 12.7 1.4 1.6 8.2 0.0 3.5 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Xpo1 PF08389.12 EMC96592.1 - 0.12 12.4 0.3 1.4 9.0 0.0 3.1 2 2 0 2 2 2 0 Exportin 1-like protein DUF1529 PF07485.11 EMC96592.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) DUF382 PF04037.13 EMC96593.1 - 1.7e-57 193.0 0.3 1.7e-57 193.0 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EMC96593.1 - 5e-21 74.3 5.4 9.8e-21 73.4 5.4 1.5 1 0 0 1 1 1 1 PSP GBR2_CC PF18455.1 EMC96595.1 - 0.043 14.0 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain RabGAP-TBC PF00566.18 EMC96596.1 - 2.3e-27 96.1 0.0 3.6e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ACCA PF03255.14 EMC96596.1 - 0.028 14.3 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MMS1_N PF10433.9 EMC96597.1 - 8.7e-77 258.8 0.0 1.7e-76 257.9 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Avl9 PF09794.9 EMC96598.1 - 7.4e-133 442.9 0.0 9.5e-133 442.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EMC96598.1 - 3.7e-08 33.3 0.1 0.00031 20.7 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 EMC96598.1 - 3.8e-08 33.3 0.0 7.7e-06 25.7 0.0 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SBBP PF06739.11 EMC96598.1 - 0.057 13.4 1.9 0.067 13.2 0.2 1.9 2 0 0 2 2 2 0 Beta-propeller repeat Chorion_2 PF03964.15 EMC96598.1 - 0.68 10.8 4.8 1.5 9.7 4.8 1.5 1 0 0 1 1 1 0 Chorion family 2 ADK PF00406.22 EMC96599.1 - 1.9e-59 200.1 0.0 2.2e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EMC96599.1 - 7e-24 84.8 0.1 1.6e-23 83.6 0.0 1.6 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 EMC96599.1 - 2.1e-17 62.8 0.0 4.4e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EMC96599.1 - 8.6e-06 26.3 0.0 1.5e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMC96599.1 - 0.00019 21.6 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EMC96599.1 - 0.032 14.0 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Alpha-amylase_C PF02806.18 EMC96601.1 - 1.2e-26 93.0 0.1 2.3e-26 92.1 0.1 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EMC96601.1 - 8.1e-15 55.0 0.0 2.1e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EMC96601.1 - 5e-13 49.3 0.2 4.3e-10 39.7 0.2 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AAA_2 PF07724.14 EMC96602.1 - 2.4e-40 138.4 0.0 3.8e-39 134.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EMC96602.1 - 5.5e-15 56.0 0.0 9.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EMC96602.1 - 2.2e-07 30.8 0.0 4.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EMC96602.1 - 2.5e-07 30.8 0.0 8.1e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EMC96602.1 - 0.00033 20.1 0.4 0.014 14.7 0.1 2.8 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM PF00493.23 EMC96602.1 - 0.0012 18.0 0.1 0.0021 17.2 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 EMC96602.1 - 0.0013 18.4 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 EMC96602.1 - 0.0016 18.7 0.2 0.02 15.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC96602.1 - 0.0017 18.7 0.1 0.01 16.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EMC96602.1 - 0.0018 18.0 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMC96602.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EMC96602.1 - 0.021 14.6 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EMC96602.1 - 0.044 13.3 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EMC96602.1 - 0.059 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EMC96602.1 - 0.066 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EMC96602.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMC96602.1 - 0.071 13.7 1.7 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EMC96602.1 - 0.09 13.3 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Aminotran_5 PF00266.19 EMC96603.1 - 1.2e-17 63.9 0.0 3e-17 62.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMC96603.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2034 PF10356.9 EMC96604.1 - 2.4e-24 85.8 0.0 5.7e-12 45.4 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EMC96604.1 - 2.8e-09 37.0 0.0 3.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 EMC96605.1 - 1.8e-41 141.7 12.8 4.7e-41 140.4 12.8 1.6 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.10 EMC96605.1 - 0.0004 20.5 0.1 0.0006 20.0 0.1 1.2 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) APG6_N PF17675.1 EMC96605.1 - 0.0025 18.3 0.6 0.004 17.7 0.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region PBC PF03792.13 EMC96605.1 - 0.029 14.1 0.1 0.047 13.5 0.1 1.3 1 0 0 1 1 1 0 PBC domain Membralin PF09746.9 EMC96606.1 - 0.083 11.9 0.0 0.095 11.7 0.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein TPR_1 PF00515.28 EMC96607.1 - 7.8e-10 38.2 11.3 9.6e-05 22.0 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMC96607.1 - 1.4e-08 34.3 2.9 0.004 16.8 0.0 4.8 2 1 2 4 4 4 2 TPR repeat TPR_2 PF07719.17 EMC96607.1 - 8e-07 28.7 24.9 9.3e-05 22.3 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMC96607.1 - 1.9e-06 27.6 3.4 0.0011 19.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMC96607.1 - 5e-06 26.5 4.0 0.21 12.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMC96607.1 - 1.4e-05 25.2 15.6 7.3e-05 23.0 4.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMC96607.1 - 0.0017 18.8 0.5 0.0017 18.8 0.5 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EMC96607.1 - 0.0029 17.7 0.8 0.0029 17.7 0.8 4.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EMC96607.1 - 0.0034 18.1 0.6 0.0034 18.1 0.6 6.6 4 2 3 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC96607.1 - 0.031 14.5 2.2 0.077 13.2 1.4 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EMC96607.1 - 0.2 12.4 20.2 0.55 10.9 3.5 4.4 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMC96607.1 - 0.45 10.7 13.6 0.27 11.3 0.2 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat AF-4 PF05110.13 EMC96608.1 - 0.62 8.1 3.3 0.78 7.7 3.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein WhiA_N PF10298.9 EMC96609.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain 2-oxoacid_dh PF00198.23 EMC96610.1 - 1.1e-74 250.8 0.3 1.3e-74 250.5 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMC96610.1 - 1.1e-16 60.4 0.4 2.6e-16 59.2 0.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Sec7 PF01369.20 EMC96611.1 - 2.6e-72 242.4 1.1 2.6e-72 242.4 1.1 2.1 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 EMC96611.1 - 1.6e-39 135.3 1.1 4.1e-39 134.0 0.0 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EMC96611.1 - 4.5e-32 109.8 7.4 6.3e-32 109.3 0.0 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 EMC96611.1 - 5e-19 68.6 3.8 6e-19 68.4 0.3 2.9 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Methyltransf_31 PF13847.6 EMC96614.1 - 7.9e-13 48.5 0.0 5.8e-12 45.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC96614.1 - 3.7e-10 40.4 0.3 4.4e-09 36.9 0.2 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC96614.1 - 7.4e-10 39.4 0.5 1.2e-07 32.3 0.1 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC96614.1 - 4.1e-06 27.5 0.0 7.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC96614.1 - 5.3e-06 26.1 0.0 9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EMC96614.1 - 1.8e-05 24.6 0.0 0.00015 21.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC96614.1 - 2.4e-05 23.8 0.0 6.8e-05 22.3 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EMC96614.1 - 3.3e-05 23.4 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 EMC96614.1 - 9.8e-05 22.2 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EMC96614.1 - 0.0007 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMC96614.1 - 0.0033 16.8 0.0 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EMC96614.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EMC96614.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 EMC96614.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 EMC96614.1 - 0.022 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.19 EMC96614.1 - 0.083 13.0 0.2 0.21 11.7 0.0 1.7 2 1 0 2 2 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EMC96614.1 - 0.089 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F tRNA_U5-meth_tr PF05958.11 EMC96614.1 - 0.26 10.2 0.0 0.39 9.6 0.0 1.4 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase SKN1 PF03935.15 EMC96615.1 - 2.6e-219 728.8 9.6 3e-219 728.6 9.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF5411 PF17424.2 EMC96615.1 - 0.58 10.1 1.3 1.1 9.2 0.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5411) MFS_1 PF07690.16 EMC96617.1 - 1.3e-39 136.2 43.7 1.3e-39 136.2 43.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EMC96617.1 - 3.2 5.9 13.0 0.78 8.0 5.1 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 EMC96618.1 - 2.6e-12 46.4 0.4 4.4e-12 45.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC96618.1 - 1.8e-07 31.2 12.8 1.8e-07 31.2 12.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamitin PF04912.14 EMC96618.1 - 0.096 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Dynamitin ABC_membrane PF00664.23 EMC96619.1 - 6.4e-82 275.3 33.7 2.6e-44 151.9 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMC96619.1 - 1.1e-63 213.8 0.0 6.2e-31 107.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMC96619.1 - 6.9e-12 45.3 3.9 0.0062 16.0 0.1 4.2 3 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMC96619.1 - 4e-09 37.1 1.9 0.00054 20.4 0.1 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EMC96619.1 - 4.2e-07 30.3 0.5 0.15 12.4 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EMC96619.1 - 5.7e-07 29.2 0.4 0.026 14.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMC96619.1 - 7.1e-07 29.3 0.0 0.031 14.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EMC96619.1 - 4.3e-06 26.7 0.0 0.069 12.8 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.9 EMC96619.1 - 2.1e-05 23.5 0.7 0.0046 15.8 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 EMC96619.1 - 3.1e-05 23.6 0.2 0.098 12.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 EMC96619.1 - 3.9e-05 23.0 0.0 0.006 15.9 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.6 EMC96619.1 - 3.9e-05 23.8 0.0 0.18 12.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.15 EMC96619.1 - 5.4e-05 23.2 0.3 0.35 10.8 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 EMC96619.1 - 9.3e-05 22.4 0.0 0.65 10.0 0.0 3.3 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 EMC96619.1 - 0.00021 21.7 4.3 2.4 8.6 0.5 4.8 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EMC96619.1 - 0.00032 21.3 0.3 0.81 10.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EMC96619.1 - 0.0005 19.9 0.0 3.1 7.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain G-alpha PF00503.20 EMC96619.1 - 0.00084 18.6 0.0 0.59 9.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 EMC96619.1 - 0.0012 18.4 0.1 2 7.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 EMC96619.1 - 0.0021 17.9 0.0 5.6 6.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 EMC96619.1 - 0.0032 17.8 0.0 4.2 7.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.6 EMC96619.1 - 0.0072 16.5 1.6 0.95 9.7 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 EMC96619.1 - 0.0081 16.2 0.0 5.7 7.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EMC96619.1 - 0.019 15.2 0.0 7.9 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMC96619.1 - 0.022 15.3 0.0 3.6 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EMC96619.1 - 0.045 13.5 0.1 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 EMC96619.1 - 0.11 12.6 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 EMC96619.1 - 0.19 10.9 0.2 18 4.4 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain V-SNARE_C PF12352.8 EMC96620.1 - 1.4e-14 54.1 0.2 3.4e-14 52.9 0.2 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EMC96620.1 - 0.00077 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Sec20 Snapin_Pallidin PF14712.6 EMC96620.1 - 0.003 17.9 0.2 0.026 14.9 0.0 2.1 2 0 0 2 2 2 1 Snapin/Pallidin Sigma70_r4 PF04545.16 EMC96620.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 MRAP PF15183.6 EMC96620.1 - 0.21 11.6 0.5 0.39 10.7 0.5 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family TPR_MLP1_2 PF07926.12 EMC96620.1 - 0.74 9.9 4.7 0.76 9.8 1.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SnoaL_4 PF13577.6 EMC96621.1 - 6.8e-16 58.6 0.1 1.2e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain RPE65 PF03055.15 EMC96623.1 - 1.5e-102 344.2 0.0 1.9e-102 343.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein adh_short PF00106.25 EMC96624.1 - 2.9e-22 79.1 0.0 2.4e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96624.1 - 2.9e-13 49.9 0.1 3.2e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96624.1 - 3.9e-06 26.9 0.8 9.5e-05 22.4 0.1 2.2 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.18 EMC96624.1 - 0.0064 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMC96624.1 - 0.017 15.2 0.0 1 9.4 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase RIBIOP_C PF04950.12 EMC96625.1 - 1.6e-94 316.6 0.0 1.6e-94 316.6 0.0 1.7 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EMC96625.1 - 2.5e-28 98.0 0.0 7.9e-28 96.4 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EMC96625.1 - 1.4e-05 25.3 0.0 5.2e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EMC96625.1 - 2.2e-05 24.1 0.0 0.01 15.4 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EMC96625.1 - 0.00013 22.4 1.9 0.00017 22.0 0.0 2.2 3 0 0 3 3 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EMC96625.1 - 0.00041 20.4 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 EMC96625.1 - 0.0014 19.1 0.0 0.0037 17.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EMC96625.1 - 0.0025 17.0 0.0 0.0067 15.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 EMC96625.1 - 0.0044 17.5 1.3 0.013 16.0 0.0 2.4 2 0 0 2 2 1 1 ABC transporter AAA_19 PF13245.6 EMC96625.1 - 0.0049 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMC96625.1 - 0.0068 16.6 0.0 0.0068 16.6 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_18 PF13238.6 EMC96625.1 - 0.009 16.6 0.1 0.009 16.6 0.1 3.7 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EMC96625.1 - 0.029 14.1 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EMC96625.1 - 0.038 13.9 0.3 0.46 10.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 EMC96625.1 - 0.041 13.8 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 EMC96625.1 - 0.041 13.5 0.2 0.083 12.5 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EMC96625.1 - 0.053 13.9 0.1 0.15 12.4 0.0 1.8 2 0 0 2 2 1 0 RNA helicase NTPase_1 PF03266.15 EMC96625.1 - 0.062 13.2 0.4 0.13 12.1 0.4 1.6 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 EMC96625.1 - 0.063 13.2 1.2 0.1 12.5 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea MeaB PF03308.16 EMC96625.1 - 0.063 12.2 0.0 0.2 10.6 0.0 1.8 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 EMC96625.1 - 0.072 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.14 EMC96625.1 - 0.082 12.9 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EMC96625.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 EMC96625.1 - 0.1 13.0 0.1 0.1 13.0 0.1 3.5 3 1 1 4 4 2 0 AAA domain Rad17 PF03215.15 EMC96625.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 EMC96625.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 EMC96625.1 - 0.12 12.4 0.1 0.44 10.6 0.1 2.0 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EMC96625.1 - 0.12 12.1 0.1 1.7 8.4 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EMC96625.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Inhibitor_I9 PF05922.16 EMC96626.1 - 0.00013 22.6 0.1 0.00015 22.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 MCM PF00493.23 EMC96627.1 - 8.6e-96 319.4 0.1 1.4e-95 318.7 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EMC96627.1 - 7.2e-31 106.7 0.0 1.3e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EMC96627.1 - 1.6e-23 82.9 0.6 3.4e-23 81.9 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EMC96627.1 - 8.3e-11 42.4 0.0 2.4e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EMC96627.1 - 1.6e-06 27.6 0.0 1.9e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EMC96627.1 - 0.0033 17.3 0.0 0.0077 16.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMC96627.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EMC96627.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Ribosomal_L1 PF00687.21 EMC96628.1 - 7.4e-65 218.5 0.2 9.3e-65 218.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Whi5 PF08528.11 EMC96630.1 - 1.4e-09 37.4 0.1 3.4e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Whi5 like BCDHK_Adom3 PF10436.9 EMC96632.1 - 2e-43 148.0 0.0 3.1e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EMC96632.1 - 6.9e-10 39.4 0.2 1.2e-07 32.2 0.2 3.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EMC96632.1 - 0.071 12.9 0.2 0.55 10.1 0.2 2.2 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dsrm PF00035.26 EMC96633.1 - 7.6e-07 29.7 0.0 1.7e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 EMC96633.1 - 7.5e-05 23.3 0.1 0.0022 18.6 0.0 2.9 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EMC96633.1 - 0.00069 19.8 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like NmrA PF05368.13 EMC96635.1 - 3.2e-17 62.9 0.0 3.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC96635.1 - 3.8e-08 33.4 0.0 2.2e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding FAD_binding_7 PF03441.14 EMC96635.1 - 0.14 11.7 0.0 0.34 10.3 0.0 1.8 1 1 0 1 1 1 0 FAD binding domain of DNA photolyase Ldh_1_C PF02866.18 EMC96636.1 - 1.4e-44 152.0 0.0 2.7e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EMC96636.1 - 2e-44 151.1 0.0 3.5e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMC96636.1 - 0.0027 16.8 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EMC96636.1 - 0.05 13.2 0.0 0.32 10.5 0.1 2.1 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 EMC96636.1 - 0.11 12.9 0.9 0.19 12.2 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Carn_acyltransf PF00755.20 EMC96637.1 - 1e-200 668.3 0.3 1.2e-200 668.1 0.3 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RTA1 PF04479.13 EMC96638.1 - 2.3e-38 131.9 7.2 3.3e-38 131.4 7.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Corona_M PF01635.18 EMC96638.1 - 3.4 6.9 7.7 1.3 8.3 4.9 1.7 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein Mob1_phocein PF03637.17 EMC96641.1 - 5.3e-71 238.1 0.0 7.4e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family ATE_C PF04377.15 EMC96642.1 - 1.7e-47 161.4 3.7 3.1e-47 160.6 3.7 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EMC96642.1 - 3.8e-25 88.1 1.1 1.3e-24 86.4 1.1 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus NUDIX PF00293.28 EMC96644.1 - 9.5e-16 58.0 3.9 1.1e-15 57.8 3.9 1.1 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 EMC96647.1 - 1.7e-65 221.0 0.0 2.6e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC96647.1 - 1.4e-45 155.7 0.0 2.2e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EMC96647.1 - 5.3e-25 87.7 0.0 1.4e-24 86.4 0.0 1.8 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 EMC96647.1 - 7.6e-17 61.5 0.0 1.6e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EMC96647.1 - 1.1e-16 60.7 0.0 2.4e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 EMC96647.1 - 2.3e-07 30.5 0.0 7.3e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SAM_4 PF18017.1 EMC96647.1 - 0.00037 20.4 0.2 0.00081 19.3 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EMC96647.1 - 0.002 18.7 0.0 0.004 17.8 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 EMC96647.1 - 0.014 14.2 0.0 0.031 13.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EMC96647.1 - 0.066 12.2 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EMC96647.1 - 0.091 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain GMC_oxred_N PF00732.19 EMC96648.1 - 1.3e-61 208.6 0.0 1.7e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC96648.1 - 2.1e-22 80.2 0.0 4.5e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMC96648.1 - 7.7e-06 25.2 0.4 0.013 14.6 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 EMC96648.1 - 1.1e-05 24.9 0.0 0.088 12.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC96648.1 - 2.9e-05 23.4 0.0 0.0051 16.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC96648.1 - 3.7e-05 23.5 0.5 0.0059 16.2 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMC96648.1 - 0.0011 18.2 0.4 0.0029 16.9 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EMC96648.1 - 0.0024 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMC96648.1 - 0.0036 17.5 0.1 0.0098 16.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMC96648.1 - 0.036 12.8 0.1 0.25 10.0 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein OCRE PF17780.1 EMC96648.1 - 0.11 12.6 2.3 0.42 10.7 0.1 2.8 3 0 0 3 3 3 0 OCRE domain TrkA_N PF02254.18 EMC96648.1 - 0.11 12.7 0.1 0.35 11.1 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 EMC96648.1 - 0.16 11.0 0.1 15 4.6 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) WD40 PF00400.32 EMC96649.1 - 1.6e-07 31.9 1.8 0.014 16.2 0.0 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC96649.1 - 2.6e-07 30.8 0.0 0.35 11.2 0.0 4.5 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PPTA PF01239.22 EMC96651.1 - 1.8e-40 135.5 14.2 1.7e-07 30.7 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat IreB PF06135.12 EMC96651.1 - 0.051 13.8 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 IreB regulatory phosphoprotein Pribosyl_synth PF14572.6 EMC96652.1 - 1.4e-45 155.6 0.5 4e-39 134.6 0.5 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EMC96652.1 - 9.5e-38 128.7 0.8 3.9e-37 126.7 0.1 2.3 3 1 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EMC96652.1 - 7e-16 58.1 0.5 1.5e-15 57.1 0.5 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMC96652.1 - 0.00091 18.7 0.1 0.0014 18.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S6e PF01092.19 EMC96653.1 - 5.4e-59 197.6 0.6 8.7e-59 197.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e MFS_1 PF07690.16 EMC96654.1 - 3.7e-36 124.8 30.9 3.7e-36 124.8 30.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC96654.1 - 6.1e-16 58.3 4.6 6.1e-16 58.3 4.6 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter AA_permease PF00324.21 EMC96655.1 - 2.5e-103 346.3 38.8 2.8e-103 346.1 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EMC96655.1 - 1.6e-23 83.2 44.0 2.2e-23 82.8 44.0 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 EMC96656.1 - 2.5e-64 217.7 0.0 3e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trimer_CC PF08954.11 EMC96656.1 - 0.27 10.8 1.1 0.62 9.7 0.2 2.0 2 0 0 2 2 2 0 Trimerisation motif ADH_zinc_N PF00107.26 EMC96657.1 - 1.5e-21 76.7 0.7 3.2e-21 75.7 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC96657.1 - 6.6e-09 36.9 0.0 1.5e-08 35.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC96657.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 EMC96657.1 - 0.066 13.4 0.3 0.17 12.1 0.3 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal adh_short PF00106.25 EMC96657.1 - 0.11 11.9 0.5 0.26 10.7 0.5 1.6 1 0 0 1 1 1 0 short chain dehydrogenase KH_1 PF00013.29 EMC96659.1 - 4e-31 106.6 3.3 7.5e-07 28.9 0.2 7.5 8 0 0 8 8 8 5 KH domain CLASP_N PF12348.8 EMC96660.1 - 1e-110 368.7 3.1 9.4e-78 260.9 0.1 2.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 EMC96660.1 - 0.00032 20.7 5.3 0.11 12.8 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EMC96660.1 - 0.013 15.6 0.1 5.8 6.9 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMC96660.1 - 0.82 10.1 17.5 0.91 10.0 0.3 4.7 3 2 2 5 5 5 0 HEAT repeats HEAT_EZ PF13513.6 EMC96660.1 - 5.3 7.6 13.5 2 9.0 1.4 3.9 5 0 0 5 5 5 0 HEAT-like repeat BSP PF04450.12 EMC96661.1 - 7e-68 228.5 0.0 7.9e-68 228.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria HAD_2 PF13419.6 EMC96663.1 - 9.3e-13 48.6 0.0 1.3e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMC96663.1 - 1.5e-09 38.5 0.0 9.5e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC96663.1 - 3.2e-05 23.9 0.0 5.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like RhoGAP PF00620.27 EMC96665.1 - 3.7e-47 159.9 0.0 1.2e-46 158.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EMC96665.1 - 1.8e-13 50.5 12.5 1.2e-07 31.8 0.1 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.10 EMC96665.1 - 0.73 10.0 14.3 1.2 9.3 1.2 3.5 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 EMC96665.1 - 0.95 9.0 14.5 0.86 9.1 0.0 3.9 4 1 0 4 4 4 0 zinc-ribbon domain Seryl_tRNA_N PF02403.22 EMC96665.1 - 1.1 9.5 12.6 1 9.6 0.3 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Desulfoferrod_N PF06397.12 EMC96665.1 - 2.2 8.0 6.5 13 5.5 0.9 2.6 1 1 1 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF4407 PF14362.6 EMC96665.1 - 5.8 6.2 11.3 14 5.0 11.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 EMC96665.1 - 6 7.1 23.6 0.6 10.3 2.7 3.2 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 EMC96665.1 - 7.7 4.3 5.8 13 3.5 5.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 EMC96665.1 - 8.2 6.5 18.7 23 5.0 18.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CorA PF01544.18 EMC96665.1 - 8.8 5.6 9.2 15 4.8 9.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DASH_Ask1 PF08655.10 EMC96666.1 - 6.5e-31 106.0 0.2 1.1e-30 105.3 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 adh_short PF00106.25 EMC96667.1 - 1.2e-50 171.8 0.7 1.4e-50 171.5 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96667.1 - 9.9e-47 159.5 0.8 1.8e-46 158.6 0.8 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96667.1 - 5.3e-11 42.8 0.2 9.4e-11 41.9 0.2 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMC96667.1 - 0.00016 21.3 0.2 0.00048 19.6 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC96667.1 - 0.0052 16.0 0.5 0.0075 15.4 0.5 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NanE PF04131.14 EMC96667.1 - 0.0079 15.4 0.3 1.8 7.7 0.1 2.2 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase HHH_5 PF14520.6 EMC96667.1 - 0.021 15.4 0.1 0.51 11.0 0.0 2.9 2 1 0 3 3 3 0 Helix-hairpin-helix domain DUF1482 PF07358.11 EMC96667.1 - 0.082 12.8 0.2 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) THF_DHG_CYH_C PF02882.19 EMC96667.1 - 0.084 12.2 0.2 0.39 10.0 0.2 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Myb_DNA-binding PF00249.31 EMC96669.1 - 1.4e-23 82.8 0.7 1.3e-13 50.9 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC96669.1 - 7.6e-16 58.1 1.4 5.1e-12 45.9 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EMC96669.1 - 0.00072 19.6 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 SLIDE DUF2774 PF11242.8 EMC96669.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Glyco_transf_41 PF13844.6 EMC96670.1 - 1.5e-103 346.8 0.0 9.7e-52 176.0 0.0 3.1 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EMC96670.1 - 2.7e-17 61.4 6.6 0.00013 21.8 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EMC96670.1 - 2.9e-17 61.7 5.2 9.8e-05 22.0 0.0 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMC96670.1 - 2.5e-14 52.2 0.5 0.0022 18.1 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMC96670.1 - 3.9e-14 52.1 10.5 2.9e-05 23.6 0.1 4.5 2 1 2 4 4 4 3 TPR repeat TPR_17 PF13431.6 EMC96670.1 - 8.4e-14 50.9 3.3 0.0014 18.9 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMC96670.1 - 2.8e-13 50.2 5.6 1.1e-06 29.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EMC96670.1 - 3e-11 43.4 6.6 0.00011 22.4 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMC96670.1 - 3.3e-10 40.4 5.5 0.00017 22.1 0.0 3.7 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMC96670.1 - 4e-10 39.6 6.3 0.021 15.6 0.0 6.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EMC96670.1 - 5.7e-10 38.7 10.1 0.037 13.9 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMC96670.1 - 1.1e-09 37.6 1.6 0.024 14.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat BTAD PF03704.17 EMC96670.1 - 7.9e-06 26.4 1.1 0.0051 17.3 0.0 2.9 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 EMC96670.1 - 8.3e-05 21.9 1.6 0.025 13.8 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC96670.1 - 0.0014 18.8 0.4 0.0099 16.1 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EMC96670.1 - 0.0064 16.6 5.9 0.62 10.2 0.4 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMC96670.1 - 0.1 13.3 0.3 64 4.5 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMC96670.1 - 0.1 12.7 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 1 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EMC96670.1 - 0.12 12.4 1.3 35 4.6 0.2 3.5 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Putative_PNPOx PF01243.20 EMC96671.1 - 9.3e-05 22.5 0.0 0.0002 21.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HD PF01966.22 EMC96672.1 - 1e-05 25.7 1.9 1.4e-05 25.3 0.9 1.7 2 0 0 2 2 2 1 HD domain MitMem_reg PF13012.6 EMC96673.1 - 7.8e-38 129.3 0.2 1.5e-37 128.5 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EMC96673.1 - 3.9e-32 110.7 0.1 5.8e-31 106.9 0.0 2.4 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EMC96673.1 - 0.0038 17.0 7.1 0.0056 16.4 7.1 1.2 1 0 0 1 1 1 1 Possible tRNA binding domain Mak10 PF04112.13 EMC96673.1 - 0.011 15.2 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase HlyD_D23 PF16576.5 EMC96673.1 - 0.11 11.7 1.8 0.18 11.0 1.8 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion CLN3 PF02487.17 EMC96673.1 - 0.41 9.6 0.9 0.6 9.1 0.9 1.2 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 EMC96673.1 - 2.4 7.8 6.5 3.9 7.2 6.5 1.3 1 0 0 1 1 1 0 Connexin DUF1682 PF07946.14 EMC96673.1 - 4.5 6.4 17.7 7.9 5.6 17.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SWIM PF04434.17 EMC96674.1 - 0.00013 21.6 0.8 0.027 14.1 0.1 2.3 2 0 0 2 2 2 2 SWIM zinc finger ETF PF01012.21 EMC96675.1 - 1.2e-43 149.1 1.0 2.4e-43 148.1 1.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EMC96675.1 - 3e-33 113.7 0.1 5.8e-33 112.8 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain DUF3496 PF12001.8 EMC96677.1 - 0.043 14.2 8.9 0.027 14.8 6.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) ALMT PF11744.8 EMC96677.1 - 0.7 8.6 4.6 0.26 10.1 1.3 1.6 1 1 1 2 2 2 0 Aluminium activated malate transporter GFA PF04828.14 EMC96679.1 - 1.2e-14 54.4 0.2 1.5e-14 54.1 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF4989 PF16379.5 EMC96679.1 - 0.12 11.6 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4989) ABC_tran PF00005.27 EMC96681.1 - 8e-49 165.7 0.4 1.1e-23 84.2 0.0 3.5 2 1 0 2 2 2 2 ABC transporter 4HB PF17947.1 EMC96681.1 - 7.6e-29 99.6 1.5 1.7e-28 98.5 0.2 2.4 2 0 0 2 2 1 1 Four helical bundle domain SMC_N PF02463.19 EMC96681.1 - 7.8e-18 64.7 0.2 5.1e-06 26.1 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMC96681.1 - 6.6e-17 62.3 0.3 0.0019 18.1 0.1 5.0 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMC96681.1 - 1.3e-10 42.1 9.3 1.2e-05 26.0 0.0 4.4 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.6 EMC96681.1 - 2.3e-08 33.6 0.1 0.0043 16.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMC96681.1 - 7.6e-08 32.4 0.0 0.00012 22.1 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 EMC96681.1 - 9.9e-08 32.4 0.0 0.022 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 EMC96681.1 - 2.1e-06 27.5 0.1 0.068 12.9 0.0 3.0 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EMC96681.1 - 3e-06 27.3 0.0 0.0032 17.5 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EMC96681.1 - 5e-06 26.8 0.0 0.17 12.2 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 EMC96681.1 - 8.8e-06 26.2 0.1 0.12 12.8 0.1 4.3 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) HEAT_2 PF13646.6 EMC96681.1 - 1e-05 25.8 0.0 0.045 14.1 0.1 3.2 1 1 0 2 2 2 1 HEAT repeats G-alpha PF00503.20 EMC96681.1 - 2.4e-05 23.7 0.6 0.16 11.1 0.0 2.8 3 0 0 3 3 3 2 G-protein alpha subunit AAA_16 PF13191.6 EMC96681.1 - 2.9e-05 24.5 0.0 0.5 10.7 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 EMC96681.1 - 4.1e-05 24.1 0.0 0.54 10.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain HEAT PF02985.22 EMC96681.1 - 8.5e-05 22.5 0.1 0.082 13.2 0.0 4.0 3 0 0 3 3 2 1 HEAT repeat Roc PF08477.13 EMC96681.1 - 0.00014 22.1 0.1 2 8.6 0.0 3.5 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EMC96681.1 - 0.00015 21.6 0.0 0.77 9.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 EMC96681.1 - 0.00021 20.3 0.1 0.085 11.8 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EMC96681.1 - 0.00023 21.2 0.0 1.4 9.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 EMC96681.1 - 0.00026 21.2 0.4 0.19 11.8 0.0 3.6 4 0 0 4 4 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 EMC96681.1 - 0.00028 21.2 0.0 0.67 10.4 0.0 3.1 3 0 0 3 3 2 1 RNA helicase cobW PF02492.19 EMC96681.1 - 0.00042 20.0 0.1 0.28 10.8 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EMC96681.1 - 0.00046 20.2 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EMC96681.1 - 0.00069 19.4 0.1 1.1 8.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.23 EMC96681.1 - 0.00086 19.4 0.0 0.019 15.0 0.0 3.0 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 EMC96681.1 - 0.00096 19.3 0.0 1.9 8.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 EMC96681.1 - 0.0013 18.5 6.3 0.78 9.4 0.0 4.1 6 0 0 6 6 4 2 AAA ATPase domain AAA_27 PF13514.6 EMC96681.1 - 0.0014 18.2 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EMC96681.1 - 0.0015 17.7 0.0 0.2 10.8 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 EMC96681.1 - 0.0027 17.7 0.4 1.6 8.6 0.0 3.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 EMC96681.1 - 0.0031 17.2 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 EMC96681.1 - 0.0061 16.8 0.0 2 8.7 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 EMC96681.1 - 0.0091 15.8 0.0 6.4 6.5 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 EMC96681.1 - 0.011 15.7 1.0 7.5 6.6 0.0 3.2 3 1 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DRIM PF07539.12 EMC96681.1 - 0.012 14.0 0.0 0.49 8.6 0.0 2.2 2 0 0 2 2 2 0 Down-regulated in metastasis IstB_IS21 PF01695.17 EMC96681.1 - 0.015 15.0 0.0 9 6.0 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.14 EMC96681.1 - 0.026 14.4 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 EMC96681.1 - 0.029 14.3 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 EMC96681.1 - 0.035 13.8 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 EMC96681.1 - 0.041 13.3 0.0 3.8 6.8 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI CLP1_P PF16575.5 EMC96681.1 - 0.042 13.6 0.0 3.1 7.5 0.0 2.9 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MMS19_N PF14500.6 EMC96681.1 - 0.043 13.4 0.1 17 4.9 0.0 2.9 2 1 0 3 3 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Arf PF00025.21 EMC96681.1 - 0.047 13.1 0.0 6.9 6.1 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family T2SSE PF00437.20 EMC96681.1 - 0.056 12.5 0.1 8.1 5.4 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 EMC96681.1 - 0.057 12.9 0.0 7.9 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EMC96681.1 - 0.06 13.3 0.3 12 5.7 0.1 2.8 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 EMC96681.1 - 0.062 13.3 0.0 17 5.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PRK PF00485.18 EMC96681.1 - 0.065 13.0 0.0 6.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MukB PF04310.12 EMC96681.1 - 0.087 12.6 0.1 17 5.1 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal dNK PF01712.19 EMC96681.1 - 0.099 12.5 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_25 PF13481.6 EMC96681.1 - 0.12 11.9 0.0 6.4 6.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EMC96681.1 - 0.15 11.8 0.1 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_13 PF13166.6 EMC96681.1 - 0.36 9.4 14.5 0.46 9.1 0.0 4.8 4 2 0 6 6 5 0 AAA domain Eaf7 PF07904.13 EMC96682.1 - 7e-25 87.5 0.9 4.3e-24 84.9 0.9 2.0 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Nop14 PF04147.12 EMC96682.1 - 0.038 12.2 3.9 0.039 12.2 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 EMC96682.1 - 0.49 10.1 10.7 0.66 9.7 10.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EMC96682.1 - 5.1 6.3 14.1 6.9 5.9 14.1 1.1 1 0 0 1 1 1 0 NOA36 protein Ion_trans PF00520.31 EMC96683.1 - 4.5e-07 29.4 23.2 9.5e-06 25.0 23.2 2.2 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EMC96683.1 - 3.3e-05 22.7 12.7 0.0021 16.8 12.7 2.2 1 1 0 1 1 1 1 Polycystin cation channel UPF0542 PF15086.6 EMC96683.1 - 0.067 13.1 0.0 0.3 11.0 0.0 2.1 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 DHHC PF01529.20 EMC96683.1 - 6 7.0 5.4 3.6 7.7 0.1 2.5 1 1 1 2 2 2 0 DHHC palmitoyltransferase NYD-SP28_assoc PF14775.6 EMC96683.1 - 7.7 6.7 6.9 8 6.6 0.1 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain Cupin_1 PF00190.22 EMC96684.1 - 8.8e-07 28.6 0.1 1.3e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EMC96684.1 - 1.4e-05 24.7 0.8 2.5e-05 23.9 0.8 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 EMC96684.1 - 0.0045 16.7 0.1 0.0057 16.4 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EMC96684.1 - 0.042 13.8 0.1 0.063 13.2 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 EMC96684.1 - 0.094 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Sugar_tr PF00083.24 EMC96685.1 - 6.2e-89 298.9 34.6 7.5e-89 298.6 34.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC96685.1 - 1.4e-20 73.6 58.4 9.8e-19 67.5 35.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GCP_C_terminal PF04130.13 EMC96687.1 - 1e-49 169.7 0.2 2.3e-49 168.5 0.0 1.7 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EMC96687.1 - 2.9e-08 33.7 0.1 1e-07 31.9 0.1 1.9 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Peroxin-3 PF04882.12 EMC96687.1 - 0.036 13.1 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Peroxin-3 DUF2647 PF10839.8 EMC96687.1 - 0.04 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) PORR PF11955.8 EMC96687.1 - 0.12 11.3 0.8 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Plant organelle RNA recognition domain DUF1373 PF07117.11 EMC96688.1 - 0.0023 18.0 6.6 0.0031 17.5 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1373) Ferric_reduct PF01794.19 EMC96689.1 - 4.8e-16 59.0 14.6 4.8e-16 59.0 14.6 2.6 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EMC96689.1 - 3.7e-15 56.0 0.0 7.5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMC96689.1 - 1e-13 51.7 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain 3Beta_HSD PF01073.19 EMC96690.1 - 8.5e-22 77.5 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMC96690.1 - 2.4e-21 76.3 0.0 3.6e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC96690.1 - 2.6e-16 60.0 0.0 7.6e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMC96690.1 - 7.2e-11 42.3 0.3 1.5e-10 41.3 0.1 1.6 2 1 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMC96690.1 - 9.3e-10 38.1 0.0 1.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EMC96690.1 - 4.9e-08 32.8 0.0 1.9e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMC96690.1 - 8.7e-05 21.8 0.0 0.00026 20.2 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EMC96690.1 - 0.00048 19.6 0.4 0.0011 18.5 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMC96690.1 - 0.0043 17.0 0.4 0.045 13.7 0.4 2.1 1 1 0 1 1 1 1 KR domain Ctf8 PF09696.10 EMC96691.1 - 1.1e-36 126.3 0.2 6.7e-36 123.8 0.2 2.2 1 1 0 1 1 1 1 Ctf8 HLH PF00010.26 EMC96692.1 - 0.0007 19.5 0.3 0.00095 19.1 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Coprogen_oxidas PF01218.18 EMC96695.1 - 1.3e-144 480.4 0.0 2.1e-144 479.7 0.0 1.3 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Sugar_tr PF00083.24 EMC96695.1 - 4.9e-103 345.4 16.7 6.8e-103 344.9 16.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC96695.1 - 1.6e-29 103.0 25.5 2.7e-29 102.2 18.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EMC96695.1 - 0.027 13.3 6.4 0.48 9.2 0.1 2.3 2 0 0 2 2 2 0 MFS_1 like family CDC50 PF03381.15 EMC96696.1 - 1.3e-90 303.7 0.0 1.6e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family NEAT PF05031.12 EMC96696.1 - 0.094 13.3 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Iron Transport-associated domain Peptidase_M43 PF05572.13 EMC96697.1 - 7.7e-13 48.6 0.2 1.5e-12 47.7 0.2 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EMC96697.1 - 0.00084 19.5 1.6 0.0013 18.9 1.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 EMC96697.1 - 0.001 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 EMC96697.1 - 0.0094 16.5 0.1 0.015 15.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EMC96697.1 - 0.021 14.5 0.4 0.041 13.5 0.3 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EMC96697.1 - 0.043 13.0 0.3 0.075 12.2 0.3 1.3 1 0 0 1 1 1 0 Met-zincin Jun PF03957.13 EMC96697.1 - 0.063 13.2 3.0 0.11 12.4 3.0 1.3 1 0 0 1 1 1 0 Jun-like transcription factor Lysine_decarbox PF03641.14 EMC96698.1 - 7.7e-30 103.7 0.0 1e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EMC96698.1 - 2.8e-06 27.0 0.3 6.5e-06 25.8 0.2 1.6 1 1 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 EMC96698.1 - 0.12 11.6 0.3 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote Ras PF00071.22 EMC96699.1 - 9.6e-49 165.1 0.2 8.9e-39 132.7 0.1 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EMC96699.1 - 2.4e-28 98.7 0.0 1e-18 67.7 0.0 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC96699.1 - 8.3e-12 44.9 0.0 3.3e-10 39.7 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMC96699.1 - 1.1e-07 31.6 0.0 9.9e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMC96699.1 - 1.3e-05 24.7 0.2 0.00017 21.0 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMC96699.1 - 0.0011 19.0 0.1 0.0078 16.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMC96699.1 - 0.077 12.9 0.3 3.3 7.6 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 EMC96700.1 - 7.9e-11 42.3 0.0 3e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EMC96700.1 - 5e-06 26.6 0.0 0.051 13.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 EMC96700.1 - 0.02 14.2 1.4 0.27 10.5 0.5 2.4 2 0 0 2 2 2 0 AIG1 family FeoB_N PF02421.18 EMC96700.1 - 0.12 11.9 0.0 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Chs7 PF12271.8 EMC96702.1 - 8.3e-105 350.2 6.9 9.4e-105 350.1 6.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Ssl1 PF04056.14 EMC96703.1 - 6.9e-74 247.8 0.0 9.1e-74 247.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EMC96703.1 - 5.1e-19 68.2 10.2 5.1e-19 68.2 10.2 3.3 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EMC96703.1 - 1.1e-13 51.7 0.0 2.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EMC96703.1 - 0.0004 20.7 0.0 0.00084 19.6 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 EMC96703.1 - 0.0021 17.6 1.3 0.0033 17.0 1.3 1.4 1 0 0 1 1 1 1 Transcription factor Tfb4 HeLo PF14479.6 EMC96704.1 - 1.3e-20 74.1 0.1 1.6e-20 73.8 0.1 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation FIST_C PF10442.9 EMC96704.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.5 1 1 0 1 1 1 0 FIST C domain Ank_2 PF12796.7 EMC96705.1 - 2.7e-15 56.7 1.2 1.3e-10 41.7 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMC96705.1 - 1.9e-09 37.0 0.1 0.041 14.4 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EMC96705.1 - 2.8e-09 37.0 3.5 0.043 14.3 0.1 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EMC96705.1 - 1.3e-07 32.0 0.9 0.0093 16.5 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMC96705.1 - 0.001 19.3 1.6 0.14 12.5 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMC96706.1 - 6.4e-37 125.5 4.9 6.3e-12 45.8 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMC96706.1 - 2.1e-29 102.0 1.3 1.9e-13 50.8 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMC96706.1 - 4.2e-26 88.1 2.0 4.9e-06 26.5 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EMC96706.1 - 8.5e-23 80.1 8.9 7e-09 35.8 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EMC96706.1 - 4.9e-22 77.3 11.1 1.6e-06 28.3 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat HgmA PF04209.13 EMC96706.1 - 0.1 11.3 0.1 1.6 7.4 0.0 2.0 1 1 0 2 2 2 0 homogentisate 1,2-dioxygenase RVP PF00077.20 EMC96706.1 - 0.16 12.3 0.3 0.52 10.7 0.0 2.0 2 1 0 2 2 2 0 Retroviral aspartyl protease DUF4541 PF15074.6 EMC96706.1 - 0.21 12.2 0.0 0.39 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) Gp_dh_C PF02800.20 EMC96707.1 - 5.6e-70 234.0 0.0 7.9e-70 233.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EMC96707.1 - 1.8e-38 130.9 0.0 3.9e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EMC96707.1 - 0.01 15.9 0.7 0.09 12.9 0.2 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EMC96707.1 - 0.041 13.8 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4440 PF14534.6 EMC96709.1 - 2.4e-07 31.1 0.0 2.8e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) 4HBT_2 PF13279.6 EMC96710.1 - 4.2e-07 30.5 0.0 6.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Mito_carr PF00153.27 EMC96711.1 - 1.6e-29 101.6 5.6 1.2e-13 50.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.21 EMC96712.1 - 2.9e-103 345.7 0.0 3.8e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EMC96712.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone CTD_bind PF04818.13 EMC96713.1 - 1.2e-08 35.7 0.0 2.9e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EMC96713.1 - 0.00015 21.5 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_Tnp_IS630 PF01710.16 EMC96714.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Transposase ERAP1_C PF11838.8 EMC96716.1 - 8.8e-92 308.0 0.3 3e-91 306.3 0.1 2.0 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EMC96716.1 - 2e-83 279.3 3.2 3.4e-83 278.5 3.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EMC96716.1 - 4.1e-47 160.8 0.5 9.9e-47 159.5 0.5 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain MATalpha_HMGbox PF04769.12 EMC96716.1 - 0.048 13.0 0.1 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box BC10 PF06726.12 EMC96717.1 - 2.4e-10 40.5 7.8 4.1e-10 39.8 7.8 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 B_solenoid_ydck PF18836.1 EMC96717.1 - 0.028 14.2 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK TNFR_16_TM PF18422.1 EMC96717.1 - 1 9.4 4.8 1.5 8.9 2.6 2.1 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain VKOR PF07884.14 EMC96717.1 - 4.2 7.6 9.1 7.2 6.8 9.1 1.4 1 0 0 1 1 1 0 Vitamin K epoxide reductase family DUF87 PF01935.17 EMC96718.1 - 0.0011 19.1 0.8 0.024 14.8 0.1 2.7 3 0 0 3 3 3 1 Helicase HerA, central domain ABC_tran PF00005.27 EMC96718.1 - 0.0029 18.1 1.3 0.032 14.7 0.2 2.7 2 1 0 2 2 2 1 ABC transporter Spo0M PF07070.11 EMC96718.1 - 0.028 14.0 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 SpoOM protein RsgA_GTPase PF03193.16 EMC96718.1 - 0.035 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EMC96718.1 - 0.15 12.5 2.4 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 EMC96718.1 - 0.4 10.0 4.1 1.9 7.8 0.0 2.7 2 1 0 2 2 2 0 AIG1 family Ras PF00071.22 EMC96719.1 - 1.3e-62 210.2 0.2 1.5e-62 210.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC96719.1 - 1e-35 122.6 0.3 1.4e-35 122.1 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC96719.1 - 3e-13 49.6 0.1 3.6e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMC96719.1 - 5.7e-08 32.8 0.1 8.2e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMC96719.1 - 2.4e-05 24.3 0.1 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EMC96719.1 - 0.00023 20.7 0.1 0.00084 18.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMC96719.1 - 0.00053 19.4 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMC96719.1 - 0.0033 16.9 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EMC96719.1 - 0.0041 17.4 0.1 0.027 14.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMC96719.1 - 0.0083 16.2 0.1 0.021 14.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMC96719.1 - 0.018 15.5 0.2 0.028 15.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EMC96719.1 - 0.022 14.5 0.1 0.061 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMC96719.1 - 0.024 15.0 0.1 0.036 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF1128 PF06569.11 EMC96719.1 - 0.034 14.1 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) TniB PF05621.11 EMC96719.1 - 0.042 13.3 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EMC96719.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SpoIIID PF12116.8 EMC96719.1 - 0.066 13.3 0.1 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.18 EMC96719.1 - 0.082 12.4 0.1 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 EMC96719.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 1 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 EMC96719.1 - 0.13 12.1 0.7 0.19 11.5 0.6 1.5 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 EMC96720.1 - 3e-09 36.6 0.3 9.5e-09 35.0 0.2 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCCH_3 PF15663.5 EMC96720.1 - 0.019 15.2 12.1 1.6 8.9 1.6 3.6 2 1 1 3 3 3 0 Zinc-finger containing family Torus PF16131.5 EMC96720.1 - 0.04 14.6 9.9 2.4 8.9 0.8 3.5 2 1 1 3 3 3 0 Torus domain zf_CCCH_4 PF18345.1 EMC96720.1 - 0.28 11.3 25.4 0.52 10.4 2.6 4.9 4 2 0 4 4 4 0 Zinc finger domain zf-CCCH_4 PF18044.1 EMC96720.1 - 1.1 9.2 18.0 5.7 6.9 0.8 4.1 3 2 0 3 3 3 0 CCCH-type zinc finger DUF1168 PF06658.12 EMC96720.1 - 5.3 6.9 14.0 14 5.5 14.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1168) Metallophos PF00149.28 EMC96721.1 - 4.7e-33 115.4 0.1 7e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EMC96721.1 - 5.9e-33 113.0 1.1 1.8e-32 111.5 0.3 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 EMC96721.1 - 2.9e-05 23.7 0.8 0.073 12.9 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC96721.1 - 0.053 13.6 3.1 6.3 7.2 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Phage_GPL PF05926.11 EMC96721.1 - 0.061 13.3 4.9 0.11 12.6 4.9 1.4 1 0 0 1 1 1 0 Phage head completion protein (GPL) TPR_11 PF13414.6 EMC96721.1 - 0.1 12.3 0.8 0.3 10.8 0.8 1.8 1 0 0 1 1 1 0 TPR repeat Spt4 PF06093.13 EMC96722.1 - 1.3e-31 108.5 0.0 1.4e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF2614 PF11023.8 EMC96722.1 - 0.1 12.7 0.3 0.18 11.9 0.3 1.4 1 1 0 1 1 1 0 Zinc-ribbon containing domain CPBP PF02517.16 EMC96724.1 - 3.2e-16 59.5 12.2 1e-15 57.9 9.2 2.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Abhydrolase_9_N PF15420.6 EMC96724.1 - 0.0041 17.1 2.0 1.2 9.1 1.3 2.5 2 0 0 2 2 2 2 Alpha/beta-hydrolase family N-terminus Mid1 PF12929.7 EMC96726.1 - 2.7e-156 521.1 0.9 3.2e-156 520.8 0.9 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EMC96726.1 - 0.0021 18.7 7.1 0.026 15.1 3.6 2.5 2 0 0 2 2 2 2 Fz domain Rep_fac_C PF08542.11 EMC96727.1 - 6.6e-25 87.3 0.1 3.6e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EMC96727.1 - 5.2e-13 49.1 0.0 1.7e-09 37.7 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EMC96727.1 - 1.3e-11 45.1 0.0 2.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EMC96727.1 - 1.3e-06 28.5 0.0 3.3e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC96727.1 - 6.2e-06 26.7 0.0 0.00045 20.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EMC96727.1 - 1.4e-05 25.0 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EMC96727.1 - 6.6e-05 23.2 0.0 0.054 13.8 0.0 2.5 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.13 EMC96727.1 - 0.00019 21.3 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 EMC96727.1 - 0.00032 20.5 0.0 0.00078 19.2 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EMC96727.1 - 0.00059 19.7 0.0 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EMC96727.1 - 0.0015 18.0 0.0 0.021 14.2 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EMC96727.1 - 0.0023 17.9 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain TniB PF05621.11 EMC96727.1 - 0.0063 15.9 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_assoc_2 PF16193.5 EMC96727.1 - 0.0067 16.7 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain MeaB PF03308.16 EMC96727.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 EMC96727.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMC96727.1 - 0.024 15.0 0.1 0.077 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMC96727.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMC96727.1 - 0.038 14.0 0.0 0.098 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EMC96727.1 - 0.048 13.6 0.1 0.16 11.9 0.1 1.9 1 1 1 2 2 2 0 NTPase DEAD PF00270.29 EMC96727.1 - 0.063 13.0 0.1 0.61 9.8 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase KTI12 PF08433.10 EMC96727.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 EMC96727.1 - 0.13 11.9 0.1 0.37 10.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain Glyco_hydro_47 PF01532.20 EMC96728.1 - 2.8e-172 573.7 0.0 3.3e-172 573.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Asp PF00026.23 EMC96730.1 - 4.7e-75 252.9 4.7 6.9e-75 252.4 4.7 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMC96730.1 - 7.6e-11 42.6 3.5 5.7e-09 36.5 3.5 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMC96730.1 - 0.002 18.8 0.4 7.4 7.3 0.1 3.5 2 1 0 2 2 2 2 Aspartyl protease GAS PF13851.6 EMC96731.1 - 7.3e-05 22.2 11.9 0.00014 21.3 0.7 3.5 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EMC96731.1 - 0.00015 22.3 2.5 0.00015 22.3 2.5 2.7 2 1 1 3 3 3 1 Apg6 coiled-coil region Lzipper-MIP1 PF14389.6 EMC96731.1 - 0.015 15.5 8.0 1.4 9.3 0.1 3.4 2 1 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 Baculo_PEP_C PF04513.12 EMC96731.1 - 0.02 15.0 3.1 0.11 12.6 2.4 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 EMC96731.1 - 0.029 14.4 5.3 12 6.1 0.2 3.5 3 0 0 3 3 3 0 TolA binding protein trimerisation TMF_TATA_bd PF12325.8 EMC96731.1 - 0.03 14.5 8.3 0.063 13.5 4.0 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EMC96731.1 - 0.035 13.0 8.9 0.09 11.6 6.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-F_N PF10481.9 EMC96731.1 - 0.037 13.7 7.3 0.017 14.8 3.9 1.9 1 1 0 2 2 2 0 Cenp-F N-terminal domain Spectrin PF00435.21 EMC96731.1 - 0.041 14.4 7.2 0.52 10.8 4.0 3.2 2 1 1 3 3 3 0 Spectrin repeat DUF641 PF04859.12 EMC96731.1 - 0.046 14.0 9.4 0.33 11.3 0.0 3.7 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) V-SNARE PF05008.15 EMC96731.1 - 0.073 13.5 4.2 2.3 8.6 0.1 3.5 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Fez1 PF06818.15 EMC96731.1 - 0.077 13.4 13.3 0.045 14.2 7.2 2.3 1 1 1 2 2 2 0 Fez1 Gp-FAR-1 PF05823.12 EMC96731.1 - 0.077 13.3 2.5 0.16 12.3 2.5 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PspA_IM30 PF04012.12 EMC96731.1 - 0.087 12.4 15.0 0.21 11.2 9.4 2.5 2 1 0 2 2 2 0 PspA/IM30 family DHR10 PF18595.1 EMC96731.1 - 0.11 12.5 11.9 0.038 14.1 6.5 2.5 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4201 PF13870.6 EMC96731.1 - 0.11 12.2 13.7 1.1 8.9 2.0 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) DUF2381 PF09544.10 EMC96731.1 - 0.12 11.8 5.9 0.037 13.6 0.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2381) HIP1_clath_bdg PF16515.5 EMC96731.1 - 0.18 12.4 11.5 11 6.7 2.0 3.5 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_DNA_bd PF12329.8 EMC96731.1 - 0.28 11.2 15.4 0.54 10.3 0.8 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.11 EMC96731.1 - 0.32 11.0 11.1 1.8 8.6 2.6 3.4 2 1 1 4 4 4 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EMC96731.1 - 0.48 10.6 5.5 1.3 9.2 3.4 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HrpB7 PF09486.10 EMC96731.1 - 0.49 10.8 15.4 0.66 10.4 0.2 3.2 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) ADIP PF11559.8 EMC96731.1 - 0.54 10.3 14.1 1.1 9.4 3.5 3.5 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 EMC96731.1 - 0.66 9.8 14.5 2.2 8.1 1.2 4.2 3 1 1 4 4 4 0 Septum formation initiator V_ATPase_I PF01496.19 EMC96731.1 - 0.76 7.6 3.1 1.1 7.1 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 EMC96731.1 - 1.2 9.5 8.4 0.65 10.3 1.9 3.0 3 1 1 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EMP24_GP25L PF01105.24 EMC96731.1 - 1.8 8.5 4.9 0.39 10.6 0.6 2.0 2 1 1 3 3 2 0 emp24/gp25L/p24 family/GOLD Phage_GP20 PF06810.11 EMC96731.1 - 4.2 7.2 12.6 31 4.3 0.2 3.3 2 2 1 3 3 3 0 Phage minor structural protein GP20 FadA PF09403.10 EMC96731.1 - 4.4 7.9 8.2 6.3 7.4 0.9 3.2 3 0 0 3 3 3 0 Adhesion protein FadA Csm1_N PF18504.1 EMC96731.1 - 6.1 7.3 12.5 6.6 7.2 0.4 4.1 3 1 1 5 5 5 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 EMC96731.1 - 8.2 6.4 8.0 18 5.3 0.2 3.8 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0220 PF05255.11 EMC96732.1 - 2.9e-71 238.4 5.6 3.3e-71 238.2 5.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) CarS-like PF01864.17 EMC96732.1 - 0.014 15.4 0.9 0.018 15.0 0.9 1.3 1 0 0 1 1 1 0 CDP-archaeol synthase DUF5337 PF17272.2 EMC96732.1 - 1.3 8.9 6.8 1.2 9.0 0.9 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5337) cwf21 PF08312.12 EMC96733.1 - 5.6e-19 68.0 7.9 1.5e-18 66.6 7.9 1.8 1 0 0 1 1 1 1 cwf21 domain MRP-L28 PF09812.9 EMC96733.1 - 0.007 16.5 1.3 0.007 16.5 1.3 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 Acetyltransf_7 PF13508.7 EMC96734.1 - 1e-06 29.0 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC96734.1 - 2.5e-06 27.4 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC96734.1 - 0.00011 22.5 0.0 0.00017 21.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EMC96734.1 - 0.0009 19.3 0.0 0.098 12.7 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMC96734.1 - 0.032 14.4 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3128 PF11326.8 EMC96735.1 - 2.8e-27 94.9 2.5 5.2e-27 94.0 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF2011 PF09428.10 EMC96736.1 - 3.6e-23 81.6 0.5 1.8e-22 79.4 0.0 2.1 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Ribosomal_L37 PF08561.10 EMC96736.1 - 0.49 10.9 7.4 0.81 10.2 7.4 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 zf-RING_2 PF13639.6 EMC96738.1 - 1.6e-08 34.8 8.1 3.1e-08 33.8 8.1 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMC96738.1 - 3.6e-07 29.9 4.8 6.1e-07 29.2 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC96738.1 - 4.6e-07 29.7 6.3 7.8e-07 29.0 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EMC96738.1 - 2.1e-06 27.5 6.6 3.5e-06 26.8 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC96738.1 - 2.2e-05 24.4 3.1 4.5e-05 23.4 3.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Syntaxin-5_N PF11416.8 EMC96738.1 - 0.00046 19.3 0.3 0.0014 17.8 0.3 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain zf-C3HC4_2 PF13923.6 EMC96738.1 - 0.0014 18.4 11.9 0.021 14.6 11.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMC96738.1 - 0.0046 17.2 5.1 0.01 16.1 5.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EMC96738.1 - 0.0083 15.9 8.4 0.016 15.0 8.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EMC96738.1 - 0.0085 15.9 9.1 0.11 12.4 9.1 2.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EMC96738.1 - 0.015 15.0 3.1 0.015 15.0 3.1 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-UDP PF14569.6 EMC96738.1 - 0.11 12.7 5.1 0.28 11.3 5.1 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-4CXXC_R1 PF10497.9 EMC96738.1 - 0.14 12.4 4.2 0.24 11.6 4.2 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-ANAPC11 PF12861.7 EMC96738.1 - 0.31 11.1 5.3 0.95 9.6 5.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EMC96738.1 - 0.35 11.1 7.3 0.8 9.9 7.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_5 PF17121.5 EMC96738.1 - 0.57 10.1 5.9 0.41 10.6 1.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EMC96738.1 - 0.8 9.9 6.1 2.1 8.6 6.1 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 Cupin_2 PF07883.11 EMC96739.1 - 1.5e-07 31.1 0.1 2.6e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EMC96739.1 - 0.034 13.9 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PCI PF01399.27 EMC96740.1 - 0.026 15.0 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 PCI domain AA_permease_2 PF13520.6 EMC96741.1 - 8.1e-65 219.3 42.0 2.5e-64 217.7 42.0 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC96741.1 - 3.4e-21 75.4 43.5 1.2e-20 73.5 43.5 1.7 1 1 0 1 1 1 1 Amino acid permease DUF3054 PF11255.8 EMC96742.1 - 0.12 12.9 0.1 0.83 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) Pga1 PF10333.9 EMC96745.1 - 0.00035 20.5 0.1 0.0021 17.9 0.1 2.2 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator DUF4141 PF13605.6 EMC96745.1 - 0.065 12.5 0.1 0.17 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Tubulin PF00091.25 EMC96746.1 - 2.2e-66 223.8 0.0 3.3e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMC96746.1 - 7.4e-50 168.3 0.1 1.3e-49 167.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EMC96746.1 - 0.0021 17.8 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain HET PF06985.11 EMC96747.1 - 1.2e-34 119.7 0.1 2.1e-34 118.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 EMC96750.1 - 6.9e-11 42.0 2.8 1.4e-10 41.1 2.8 1.6 1 0 0 1 1 1 1 WW domain Ras PF00071.22 EMC96751.1 - 2.7e-65 218.9 1.1 3.2e-65 218.7 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC96751.1 - 8.3e-36 122.8 1.0 1.2e-35 122.3 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC96751.1 - 1.6e-16 60.2 0.2 2e-16 59.9 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EMC96751.1 - 9.5e-06 25.6 0.8 0.13 12.1 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMC96751.1 - 2.5e-05 24.3 0.0 0.0001 22.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMC96751.1 - 5.1e-05 22.9 0.6 0.00011 21.8 0.3 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMC96751.1 - 0.00021 20.7 0.1 0.00025 20.5 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMC96751.1 - 0.00051 19.5 0.1 0.00065 19.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EMC96751.1 - 0.00096 19.6 0.1 0.15 12.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EMC96751.1 - 0.0027 17.2 0.1 0.017 14.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EMC96751.1 - 0.0084 16.5 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMC96751.1 - 0.025 14.9 0.0 0.067 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EMC96751.1 - 0.052 12.8 0.1 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 EMC96751.1 - 0.055 13.5 0.1 0.098 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EMC96751.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EMC96751.1 - 0.072 12.8 0.1 0.64 9.7 0.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EMC96751.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EMC96751.1 - 0.075 13.5 0.1 0.15 12.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EMC96751.1 - 0.08 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 EMC96751.1 - 0.15 11.6 0.2 1.5 8.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain PHD PF00628.29 EMC96752.1 - 0.015 15.2 3.6 0.038 13.9 3.6 1.7 1 0 0 1 1 1 0 PHD-finger VEFS-Box PF09733.9 EMC96752.1 - 0.035 13.9 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Aminotran_5 PF00266.19 EMC96753.1 - 2.2e-19 69.7 0.0 2.9e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.20 EMC96754.1 - 5.2e-109 365.3 0.0 3.7e-108 362.5 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMC96754.1 - 3.6e-24 85.6 0.0 7e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain SPT6_acidic PF14632.6 EMC96755.1 - 0.013 16.1 0.7 0.019 15.5 0.7 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 GYF PF02213.16 EMC96756.1 - 9.7e-17 60.4 1.5 2e-16 59.4 1.5 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EMC96756.1 - 0.0055 16.5 0.4 0.015 15.0 0.4 1.8 1 0 0 1 1 1 1 GYF domain 2 GST_N_3 PF13417.6 EMC96757.1 - 4.6e-16 59.0 0.0 8.5e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMC96757.1 - 1.4e-13 50.9 0.0 2.1e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMC96757.1 - 2e-08 34.4 0.0 3.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMC96757.1 - 2.1e-08 34.3 0.0 3.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMC96757.1 - 7.5e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMC96757.1 - 0.00035 20.5 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EMC96757.1 - 0.09 13.5 0.0 0.24 12.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain NUDIX PF00293.28 EMC96758.1 - 1.8e-16 60.4 0.0 2.3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EMC96758.1 - 0.00015 21.7 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Septin PF00735.18 EMC96760.1 - 8.7e-121 402.5 0.1 8.7e-121 402.5 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EMC96760.1 - 4e-08 33.3 1.0 6.6e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMC96760.1 - 9.9e-07 28.5 1.1 0.0001 21.9 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EMC96760.1 - 0.00034 20.8 0.0 0.00078 19.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EMC96760.1 - 0.00034 21.1 2.2 0.025 15.1 0.0 2.7 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 EMC96760.1 - 0.0012 18.7 0.6 0.0012 18.7 0.6 3.4 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 EMC96760.1 - 0.0015 17.9 1.7 0.0026 17.1 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 EMC96760.1 - 0.0018 18.6 0.0 0.0054 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMC96760.1 - 0.0045 17.3 0.9 0.017 15.4 0.0 2.4 2 2 1 3 3 3 1 AAA domain Ras PF00071.22 EMC96760.1 - 0.0046 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Ras family AAA_29 PF13555.6 EMC96760.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EMC96760.1 - 0.04 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EMC96760.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EMC96760.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EMC96760.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EMC96760.1 - 0.089 13.2 0.9 0.41 11.1 0.0 2.5 3 0 0 3 3 2 0 RNA helicase Dynamin_N PF00350.23 EMC96760.1 - 0.11 12.5 8.6 0.92 9.6 0.0 3.5 3 1 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 EMC96760.1 - 0.33 10.7 7.4 0.61 9.8 0.1 3.2 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 EMC96760.1 - 1.2 8.7 6.6 2.1 7.8 6.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EMC96760.1 - 3.9 6.5 9.8 5.9 5.9 9.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exo70 PF03081.15 EMC96761.1 - 9.6e-95 317.8 0.0 1e-93 314.4 0.0 2.2 2 1 0 2 2 2 1 Exo70 exocyst complex subunit GAS PF13851.6 EMC96761.1 - 0.00048 19.5 3.7 0.19 11.1 0.7 2.4 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding SPECT1 PF18680.1 EMC96761.1 - 0.0042 16.8 0.9 0.0084 15.8 0.4 1.7 2 0 0 2 2 2 1 Plasmodium host cell traversal SPECT1 COG6 PF06419.11 EMC96761.1 - 0.018 13.3 0.7 0.37 9.0 0.5 2.3 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 DUF4041 PF13250.6 EMC96761.1 - 0.042 13.7 2.0 0.64 9.9 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4041) T2SSF PF00482.23 EMC96761.1 - 0.097 12.6 2.3 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF883 PF05957.13 EMC96761.1 - 0.12 13.0 0.7 61 4.3 0.0 3.9 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF883) COG5 PF10392.9 EMC96761.1 - 0.14 12.4 2.9 0.45 10.7 0.1 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DASH_Duo1 PF08651.10 EMC96761.1 - 0.23 11.2 6.0 14 5.6 0.0 4.6 4 1 0 4 4 4 0 DASH complex subunit Duo1 Pex19 PF04614.12 EMC96761.1 - 0.46 10.2 2.1 1.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Pex19 protein family 3HCDH_N PF02737.18 EMC96761.1 - 0.59 10.0 2.9 0.5 10.2 0.7 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4407 PF14362.6 EMC96761.1 - 1.6 8.0 6.8 0.55 9.5 2.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EMC96761.1 - 1.9 9.0 5.2 1.7 9.2 0.1 3.6 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein PI3K_P85_iSH2 PF16454.5 EMC96761.1 - 5.4 6.6 9.6 8 6.0 0.2 3.7 2 1 1 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MFS_1 PF07690.16 EMC96762.1 - 2.3e-39 135.3 29.4 2.3e-39 135.3 29.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC96762.1 - 7.9e-08 31.6 5.3 7.9e-08 31.6 5.3 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EMC96762.1 - 0.00027 19.5 3.0 0.00027 19.5 3.0 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) TMEM169 PF15052.6 EMC96762.1 - 0.17 12.0 1.0 0.54 10.4 0.2 2.2 2 0 0 2 2 2 0 TMEM169 protein family DUF2583 PF10762.9 EMC96762.1 - 0.46 10.9 2.3 4.9 7.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) HSP70 PF00012.20 EMC96764.1 - 1.4e-163 545.3 1.4 1.4e-163 545.3 1.4 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EMC96764.1 - 8.2e-13 47.9 0.0 5e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EMC96764.1 - 0.011 16.2 3.8 0.063 13.7 0.0 3.2 3 0 0 3 3 3 0 Cell division protein FtsA p450 PF00067.22 EMC96765.1 - 3.5e-58 197.5 0.0 4.7e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tir_receptor_M PF03549.14 EMC96767.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Sel_put PF04328.13 EMC96767.1 - 0.16 12.0 0.1 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Selenoprotein, putative ABC_membrane_2 PF06472.15 EMC96768.1 - 1.4e-104 349.3 1.4 2.4e-104 348.5 1.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EMC96768.1 - 5.8e-16 59.3 0.0 1.6e-15 57.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMC96768.1 - 1.3e-05 25.2 0.0 0.00021 21.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMC96768.1 - 0.0052 17.3 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMC96768.1 - 0.014 15.1 0.0 0.6 9.8 0.0 3.2 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 EMC96768.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EMC96768.1 - 0.028 14.7 0.1 1.8 8.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 EMC96768.1 - 0.049 13.1 0.3 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMC96768.1 - 0.062 13.7 0.5 0.36 11.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EMC96768.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 EMC96768.1 - 0.12 12.1 0.3 0.24 11.0 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain GrpE PF01025.19 EMC96769.1 - 1.6e-42 145.0 0.3 2.2e-42 144.6 0.3 1.1 1 0 0 1 1 1 1 GrpE GHL13 PF14883.6 EMC96769.1 - 0.018 14.1 0.2 0.024 13.7 0.2 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 Nro1 PF12753.7 EMC96769.1 - 0.032 13.2 0.8 0.042 12.8 0.8 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Solute_trans_a PF03619.16 EMC96770.1 - 6.8e-95 317.6 4.7 8.2e-95 317.3 4.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DivIC PF04977.15 EMC96772.1 - 0.0056 16.4 0.0 0.0056 16.4 0.0 2.2 2 1 0 2 2 2 1 Septum formation initiator Shugoshin_N PF07558.11 EMC96772.1 - 0.0058 16.5 0.2 0.014 15.3 0.2 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Jnk-SapK_ap_N PF09744.9 EMC96772.1 - 0.0085 16.3 1.9 0.18 12.0 0.0 2.2 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 Atg14 PF10186.9 EMC96772.1 - 0.012 14.8 1.7 0.023 13.8 0.3 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2046 PF09755.9 EMC96772.1 - 0.013 14.8 1.6 0.03 13.6 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Cnn_1N PF07989.11 EMC96772.1 - 0.058 13.6 1.7 0.07 13.3 0.0 1.9 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF2968 PF11180.8 EMC96772.1 - 1.6 8.3 13.0 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) PLDc_2 PF13091.6 EMC96773.1 - 1.3e-19 70.5 0.1 5.4e-13 49.0 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EMC96773.1 - 0.00013 22.0 0.1 0.00082 19.5 0.1 2.2 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EMC96773.1 - 0.00075 18.8 0.0 0.0041 16.3 0.0 2.2 2 1 0 2 2 2 1 Archaeal transcriptional regulator TrmB ADH_zinc_N PF00107.26 EMC96774.1 - 2.4e-19 69.6 1.3 2.4e-19 69.6 1.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 EMC96774.1 - 0.0059 16.9 0.5 0.04 14.2 0.2 2.2 2 0 0 2 2 2 1 TrkA-N domain ADH_zinc_N_2 PF13602.6 EMC96774.1 - 0.015 16.3 0.5 0.095 13.7 0.1 2.3 2 1 1 3 3 3 0 Zinc-binding dehydrogenase DapB_N PF01113.20 EMC96774.1 - 0.11 12.6 0.8 0.2 11.8 0.8 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus EAL PF00563.20 EMC96774.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 EAL domain Cytochrom_C PF00034.21 EMC96776.1 - 1e-09 39.4 0.0 1.3e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EMC96776.1 - 5.4e-07 29.8 0.4 2.8e-06 27.5 0.4 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EMC96776.1 - 0.00088 19.0 0.1 0.0082 15.9 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Stc1 PF12898.7 EMC96777.1 - 2.7e-16 59.9 9.0 4e-16 59.3 9.0 1.2 1 0 0 1 1 1 1 Stc1 domain zf-CHY PF05495.12 EMC96777.1 - 0.0012 19.3 1.8 0.0026 18.2 1.8 1.5 1 1 0 1 1 1 1 CHY zinc finger Chorismate_bind PF00425.18 EMC96779.1 - 7.6e-89 297.7 0.2 3.4e-86 289.0 0.1 2.8 2 1 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EMC96779.1 - 2.1e-27 96.1 0.1 3.1e-24 85.8 0.0 3.2 2 1 1 3 3 3 2 Anthranilate synthase component I, N terminal region AA_permease_N PF08403.10 EMC96779.1 - 0.019 14.5 0.1 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Amino acid permease N-terminal Rootletin PF15035.6 EMC96780.1 - 0.16 12.0 6.6 0.16 12.0 4.7 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Myb_DNA-bind_5 PF13873.6 EMC96780.1 - 0.81 9.8 4.0 32 4.7 0.5 3.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain CorA PF01544.18 EMC96780.1 - 3.4 6.9 6.9 5.7 6.2 6.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 EMC96780.1 - 5.5 7.0 7.9 2.2 8.3 5.3 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ATP-synt_ab PF00006.25 EMC96781.1 - 1.7e-67 227.2 0.0 2.4e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EMC96781.1 - 6.1e-14 52.3 0.6 1.2e-13 51.4 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 EMC96781.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5535) LIM_bind PF01803.16 EMC96782.1 - 7.6e-54 182.8 0.8 7.6e-54 182.8 0.8 6.5 3 2 2 5 5 5 1 LIM-domain binding protein Pex16 PF08610.10 EMC96784.1 - 1.1e-136 455.2 0.1 1.3e-136 455.0 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) IL5 PF02025.15 EMC96785.1 - 0.21 11.9 0.0 0.21 11.9 0.0 1.0 1 0 0 1 1 1 0 Interleukin 5 Pns11_12 PF17464.2 EMC96786.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Non-structural protein 11 and 12 PLDc_2 PF13091.6 EMC96787.1 - 2.4e-15 56.6 0.0 3.7e-05 23.6 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EMC96787.1 - 3.7e-15 55.4 2.9 7.5e-08 32.3 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DLEU7 PF15760.5 EMC96787.1 - 0.085 12.3 0.1 0.085 12.3 0.1 3.2 2 1 1 3 3 3 0 Leukemia-associated protein 7 DAO PF01266.24 EMC96788.1 - 8.1e-55 186.8 0.2 1e-54 186.5 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC96788.1 - 8.4e-07 29.1 0.5 1.8e-06 28.1 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMC96788.1 - 0.00054 19.3 0.7 0.00083 18.7 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EMC96788.1 - 0.0016 18.1 0.2 0.0027 17.4 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EMC96788.1 - 0.0054 17.0 0.2 0.0098 16.1 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 EMC96788.1 - 0.0075 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EMC96788.1 - 0.019 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EMC96788.1 - 0.039 12.7 0.5 0.054 12.2 0.5 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EMC96788.1 - 0.047 12.9 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EMC96788.1 - 0.056 13.4 0.3 0.092 12.7 0.3 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EMC96788.1 - 0.065 12.3 0.5 0.12 11.3 0.5 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EMC96788.1 - 0.084 12.1 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EMC96788.1 - 0.14 11.2 0.8 0.3 10.1 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_30 PF02055.16 EMC96790.1 - 8.9e-24 84.1 0.2 1.4e-23 83.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 EMC96790.1 - 6.5e-06 26.3 0.2 6.5e-06 26.3 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 EMC96790.1 - 0.055 12.7 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Choline_transpo PF04515.12 EMC96791.1 - 5.4e-27 94.9 23.1 5.4e-27 94.9 23.1 2.7 2 2 0 2 2 2 1 Plasma-membrane choline transporter CLPTM1 PF05602.12 EMC96792.1 - 6.6e-148 493.3 0.0 7.9e-148 493.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) 2TM PF13239.6 EMC96792.1 - 0.31 11.4 0.1 0.31 11.4 0.1 2.5 2 0 0 2 2 2 0 2TM domain DUF1772 PF08592.11 EMC96792.1 - 1.1 9.5 3.6 2.4 8.5 2.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Sec16_C PF12931.7 EMC96793.1 - 7.3e-104 347.6 0.0 1e-103 347.2 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EMC96793.1 - 2e-31 109.0 0.1 8.9e-31 106.9 0.0 2.2 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Borrelia_P83 PF05262.11 EMC96793.1 - 4 5.8 5.7 7.3 4.9 5.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein EHN PF06441.12 EMC96794.1 - 1.2e-32 112.4 0.6 2.2e-32 111.6 0.6 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMC96794.1 - 4.4e-09 36.4 0.1 7.8e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC96794.1 - 0.0082 16.8 5.1 0.032 14.8 5.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Rad51 PF08423.11 EMC96795.1 - 0.0024 17.2 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 Carn_acyltransf PF00755.20 EMC96797.1 - 2.9e-206 686.6 0.0 1.8e-205 684.0 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Med26 PF08711.11 EMC96798.1 - 3.4e-10 39.8 0.0 7.1e-10 38.8 0.0 1.5 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Nup54 PF13874.6 EMC96799.1 - 7.5e-38 129.8 3.6 7.5e-38 129.8 3.6 1.5 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EMC96799.1 - 3.1e-11 42.6 0.2 5.2e-11 41.9 0.2 1.4 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 EMC96799.1 - 2.6e-09 37.8 31.5 6.4e-09 36.6 31.5 1.7 1 0 0 1 1 1 1 Nucleoporin FG repeat region Apolipoprotein PF01442.18 EMC96799.1 - 0.025 14.5 10.1 0.018 15.0 6.8 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4559 PF15112.6 EMC96799.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Cast PF10174.9 EMC96799.1 - 1.2 7.3 4.4 0.13 10.4 0.5 1.4 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Helo_like_N PF17111.5 EMC96800.1 - 0.023 14.1 0.3 0.069 12.5 0.0 1.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins E1-N PF14463.6 EMC96800.1 - 0.15 11.9 1.9 3.8 7.3 0.1 2.9 2 1 1 3 3 3 0 E1 N-terminal domain Tom5 PF10642.9 EMC96801.1 - 2.1e-21 75.6 0.4 2.3e-21 75.5 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase CHCH PF06747.13 EMC96802.1 - 3.2e-09 36.7 12.8 7.2e-08 32.4 6.0 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 EMC96802.1 - 5.4e-05 23.1 8.4 0.0013 18.7 3.9 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 EMC96802.1 - 0.0039 17.5 9.7 0.22 11.8 1.2 3.1 2 1 1 3 3 3 3 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 EMC96802.1 - 0.011 15.7 13.6 0.024 14.7 4.5 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 EMC96802.1 - 0.66 10.3 12.4 0.74 10.1 4.3 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb NDUF_B7 PF05676.13 EMC96802.1 - 1 9.1 9.8 0.32 10.8 3.5 2.2 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PCMT PF01135.19 EMC96803.1 - 0.0024 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EMC96803.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EMC96803.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EMC96803.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EMC96803.1 - 0.17 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 EMC96805.1 - 8.1e-18 63.9 0.0 1.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMC96805.1 - 0.0019 18.3 0.0 0.0023 18.0 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain RAM PF15320.6 EMC96805.1 - 0.9 10.2 9.6 1.3 9.7 9.6 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Cyclin_N PF00134.23 EMC96808.1 - 2.6e-08 33.6 0.2 2.6e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 EMC96808.1 - 0.17 12.0 0.4 0.41 10.7 0.4 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF4407 PF14362.6 EMC96809.1 - 0.29 10.5 30.4 0.36 10.1 1.8 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4715 PF15835.5 EMC96809.1 - 0.41 10.7 5.0 0.25 11.4 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) V-SNARE_C PF12352.8 EMC96809.1 - 1.1 9.5 12.2 1.8 8.9 2.3 4.0 4 1 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus DUF4803 PF16061.5 EMC96809.1 - 1.5 8.3 10.3 0.23 10.9 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4803) HrpB7 PF09486.10 EMC96809.1 - 2.5 8.5 44.8 0.13 12.6 1.0 4.5 4 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 EMC96809.1 - 4.5 7.3 18.1 3 7.9 1.1 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Bul1_C PF04426.12 EMC96809.1 - 5.6 6.3 13.8 0.35 10.3 6.1 2.5 3 0 0 3 3 3 0 Bul1 C terminus Peptidase_C98 PF15499.6 EMC96809.1 - 7.9 5.9 8.2 0.83 9.1 0.6 2.5 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PWI PF01480.17 EMC96811.1 - 8.2e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EMC96811.1 - 6.2e-06 26.0 0.1 1.2e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 EMC96811.1 - 0.0048 16.8 2.9 0.0088 15.9 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EMC96811.1 - 0.0078 16.2 2.1 0.015 15.3 2.1 1.5 1 0 0 1 1 1 1 Zinc finger domain HIP1_clath_bdg PF16515.5 EMC96811.1 - 0.0089 16.6 7.1 0.016 15.8 7.1 1.4 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 RRM_occluded PF16842.5 EMC96811.1 - 0.041 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF812 PF05667.11 EMC96811.1 - 0.052 12.4 2.1 0.073 12.0 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RRM_3 PF08777.11 EMC96811.1 - 0.083 12.9 1.9 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 RNA binding motif DUF4523 PF15023.6 EMC96811.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 EMC96811.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4407 PF14362.6 EMC96811.1 - 0.13 11.6 1.9 0.23 10.8 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1043 PF06295.12 EMC96811.1 - 0.18 11.8 1.4 0.32 11.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) HAUS6_N PF14661.6 EMC96811.1 - 0.32 10.5 4.0 0.49 9.9 3.4 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus APG6_N PF17675.1 EMC96811.1 - 1 9.9 6.9 2.2 8.8 6.9 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region BCS1_N PF08740.11 EMC96812.1 - 0.035 14.1 1.7 0.074 13.0 1.7 1.5 1 0 0 1 1 1 0 BCS1 N terminal GTP_EFTU PF00009.27 EMC96813.1 - 4.2e-66 222.2 0.2 6.3e-66 221.6 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EMC96813.1 - 3.3e-34 117.2 0.0 1.1e-33 115.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EMC96813.1 - 7.8e-23 80.3 0.0 3.1e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMC96813.1 - 7.2e-15 55.1 0.1 2.8e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EMC96813.1 - 1.7e-11 44.0 0.0 3.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EMC96813.1 - 0.00051 20.1 0.2 0.0012 18.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.32 EMC96814.1 - 2.4e-09 37.6 7.7 0.19 12.7 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Myb_DNA-bind_6 PF13921.6 EMC96814.1 - 0.017 15.3 0.1 0.087 13.1 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMC96814.1 - 0.055 13.7 0.0 0.22 11.8 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain AhpC-TSA PF00578.21 EMC96815.1 - 4e-07 30.0 0.0 7.5e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMC96815.1 - 3.2e-05 23.7 0.0 0.0026 17.5 0.0 2.1 2 0 0 2 2 2 2 Redoxin AhpC-TSA_2 PF13911.6 EMC96815.1 - 0.0018 18.4 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme UPF0121 PF03661.13 EMC96817.1 - 9.3e-32 110.3 1.9 1.2e-31 110.0 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Pribosyltran_N PF13793.6 EMC96819.1 - 2.4e-42 143.6 0.1 1e-41 141.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EMC96819.1 - 5.3e-35 121.1 0.0 1.2e-28 100.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EMC96819.1 - 1.9e-07 30.7 0.1 3.4e-05 23.4 0.0 2.6 3 0 0 3 3 3 2 Phosphoribosyl transferase domain Aldo_ket_red PF00248.21 EMC96820.1 - 1.4e-69 234.6 0.1 1.6e-69 234.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ubiquitin PF00240.23 EMC96821.1 - 1e-33 114.9 0.6 1.4e-33 114.4 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EMC96821.1 - 6.4e-16 57.9 0.7 8.8e-16 57.5 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMC96821.1 - 5.1e-05 23.7 0.2 0.00017 22.0 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EMC96821.1 - 0.0071 16.7 0.1 0.01 16.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EMC96821.1 - 0.0079 16.1 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMC96821.1 - 0.012 15.7 0.1 0.036 14.2 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMC96821.1 - 0.043 14.4 0.0 0.077 13.6 0.0 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EMC96821.1 - 0.054 13.5 1.0 8.9 6.4 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Sld5 PF05916.11 EMC96823.1 - 0.07 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 GINS complex protein ORC5_C PF14630.6 EMC96823.1 - 0.079 12.5 0.5 0.12 11.8 0.5 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus eIF-5a PF01287.20 EMC96824.1 - 8.3e-29 99.5 1.3 1.2e-28 99.0 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EMC96824.1 - 0.0039 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.12 EMC96825.1 - 3.8e-117 392.1 0.0 4.7e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EMC96825.1 - 1.8e-05 23.4 0.2 2.3e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF4795 PF16043.5 EMC96825.1 - 0.0059 16.2 0.6 0.011 15.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF812 PF05667.11 EMC96825.1 - 0.012 14.6 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) COG6 PF06419.11 EMC96825.1 - 0.016 13.5 1.5 0.025 12.8 1.5 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Sec34 PF04136.15 EMC96825.1 - 0.024 14.5 0.6 0.13 12.1 0.6 2.0 1 1 0 1 1 1 0 Sec34-like family Mer2 PF09074.10 EMC96825.1 - 0.079 12.8 0.0 0.43 10.4 0.1 2.1 3 0 0 3 3 3 0 Mer2 DUF1664 PF07889.12 EMC96825.1 - 0.21 11.6 0.2 0.55 10.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BST2 PF16716.5 EMC96825.1 - 0.45 11.1 3.6 0.23 12.1 1.1 1.8 2 0 0 2 2 1 0 Bone marrow stromal antigen 2 NPV_P10 PF05531.12 EMC96825.1 - 0.46 11.0 2.1 3.3 8.3 0.5 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EMC96825.1 - 0.59 10.4 3.7 0.92 9.8 0.5 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SSP160 PF06933.11 EMC96826.1 - 2.2 6.4 14.1 2.9 6.0 14.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 adh_short PF00106.25 EMC96827.1 - 9.4e-20 70.9 0.0 3e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96827.1 - 1.1e-09 38.2 0.0 4.5e-09 36.2 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96827.1 - 1.9e-06 27.9 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMC96827.1 - 0.069 12.5 0.1 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMC96827.1 - 0.089 12.2 0.0 0.12 11.8 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMC96827.1 - 0.14 12.4 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3439 PF11921.8 EMC96828.1 - 0.0034 17.3 9.7 0.0079 16.2 9.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EMC96828.1 - 0.018 13.0 1.9 0.023 12.7 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 EMC96828.1 - 0.37 9.0 10.9 0.54 8.4 10.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 S4 PF01479.25 EMC96829.1 - 2.8e-14 52.6 0.0 5.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EMC96829.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 S4 domain Perilipin PF03036.16 EMC96829.1 - 0.62 9.0 10.8 0.91 8.5 10.8 1.2 1 0 0 1 1 1 0 Perilipin family RR_TM4-6 PF06459.12 EMC96829.1 - 6.4 6.5 16.9 7 6.4 7.3 2.2 1 1 1 2 2 2 0 Ryanodine Receptor TM 4-6 Seryl_tRNA_N PF02403.22 EMC96829.1 - 8.5 6.7 10.7 2.4 8.4 3.7 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain La PF05383.17 EMC96830.1 - 6.1e-19 67.8 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EMC96830.1 - 1.2e-07 31.4 0.0 3.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.31 EMC96831.1 - 4.9e-09 36.4 0.0 7.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C4_ClpX PF06689.13 EMC96831.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger AAA PF00004.29 EMC96832.1 - 7.9e-11 42.5 0.0 1.7e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EMC96832.1 - 1.9e-06 27.9 0.5 8.3e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 EMC96832.1 - 1e-05 25.5 0.0 2.8e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMC96832.1 - 4e-05 23.4 0.0 8.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EMC96832.1 - 9.5e-05 22.7 0.0 0.00062 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMC96832.1 - 0.00086 19.7 0.2 0.0093 16.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EMC96832.1 - 0.0033 17.6 0.0 0.014 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EMC96832.1 - 0.0096 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 EMC96832.1 - 0.024 14.6 0.1 0.088 12.7 0.0 2.0 1 1 0 1 1 1 0 NTPase AAA_30 PF13604.6 EMC96832.1 - 0.03 14.0 0.1 0.071 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMC96832.1 - 0.042 13.9 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMC96832.1 - 0.099 13.2 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EMC96832.1 - 0.11 12.9 0.1 0.75 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EMC96832.1 - 0.15 11.2 0.1 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 EMC96833.1 - 2.3e-15 57.2 0.0 1.1e-14 55.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMC96833.1 - 0.0012 18.8 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMC96833.1 - 0.013 15.8 0.7 0.13 12.5 0.2 2.6 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EMC96833.1 - 0.026 14.9 1.2 0.58 10.5 1.7 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EMC96833.1 - 0.028 14.1 0.1 0.08 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EMC96833.1 - 0.086 12.6 0.0 0.086 12.6 0.0 4.2 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EMC96833.1 - 0.42 10.9 2.0 1.6 9.0 0.6 2.5 2 1 0 2 2 2 0 AAA domain PPR_3 PF13812.6 EMC96834.1 - 9.1e-10 38.5 0.0 0.71 10.0 0.0 5.2 4 2 1 5 5 5 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 EMC96834.1 - 1.3e-07 31.7 0.1 20 5.5 0.0 7.2 7 1 1 8 8 8 1 PPR repeat family PPR PF01535.20 EMC96834.1 - 9.3e-07 28.7 0.1 12 6.4 0.0 7.1 8 0 0 8 8 8 1 PPR repeat PPR_long PF17177.4 EMC96834.1 - 0.0011 18.3 0.1 0.073 12.4 0.0 3.2 2 2 2 4 4 4 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 EMC96834.1 - 0.039 14.5 0.3 6 7.5 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat ScsC_N PF18312.1 EMC96834.1 - 0.047 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain TPR_14 PF13428.6 EMC96834.1 - 0.12 13.3 2.6 51 5.1 0.0 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat PPR_1 PF12854.7 EMC96834.1 - 0.13 12.0 7.4 0.18 11.5 0.0 4.5 6 0 0 6 6 6 0 PPR repeat EBV-NA1 PF02905.14 EMC96835.1 - 0.14 11.9 1.3 0.29 10.9 0.7 1.8 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Hid1 PF12722.7 EMC96836.1 - 1 7.4 5.5 1.1 7.3 5.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 EMC96837.1 - 1.4e-57 195.4 0.1 1.6e-57 195.2 0.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.13 EMC96837.1 - 0.05 13.2 2.9 0.11 12.0 0.8 2.1 2 0 0 2 2 2 0 UNC-50 family Pirin PF02678.16 EMC96838.1 - 9.4e-27 93.1 0.2 2e-26 92.1 0.2 1.5 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 EMC96838.1 - 3.3e-09 36.8 0.0 2.7e-08 33.9 0.0 2.3 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 EMC96838.1 - 0.002 17.8 1.2 0.022 14.5 0.2 2.8 3 1 0 3 3 3 1 Cupin domain adh_short PF00106.25 EMC96839.1 - 1.7e-22 79.8 0.4 2.6e-18 66.2 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96839.1 - 2.7e-13 50.1 0.1 2e-11 43.9 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96839.1 - 6.5e-08 32.7 0.2 9.1e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EMC96842.1 - 1.5e-35 122.6 0.0 2.3e-34 118.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EMC96842.1 - 5.5e-30 104.3 0.0 1.1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EMC96842.1 - 8.2e-14 51.6 0.0 1.8e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMC96842.1 - 2.4e-07 31.0 0.2 2.7e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EMC96842.1 - 3.3e-06 26.7 0.0 3.2e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMC96842.1 - 0.0012 17.9 0.0 0.0052 15.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EMC96842.1 - 0.022 14.3 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 EMC96842.1 - 0.045 13.7 0.1 0.17 11.7 0.1 2.0 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 EMC96842.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EMC96842.1 - 0.15 11.9 0.0 0.84 9.5 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H-binding adh_short PF00106.25 EMC96843.1 - 8.4e-20 71.1 0.1 3.1e-17 62.7 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96843.1 - 1.7e-10 40.9 0.1 5.6e-08 32.6 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96843.1 - 2.8e-09 37.2 0.1 4.5e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 EMC96844.1 - 1.7e-08 33.8 0.0 2.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC96844.1 - 1.5e-06 28.2 9.2 1.5e-06 28.2 9.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 EMC96844.1 - 0.019 13.4 0.0 0.028 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Sde2_N_Ubi PF13019.6 EMC96845.1 - 7e-64 214.6 0.2 7e-64 214.6 0.2 1.4 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain p450 PF00067.22 EMC96846.1 - 6.4e-41 140.6 0.0 8.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_63 PF03200.16 EMC96847.1 - 3.7e-08 32.6 13.1 9.2e-07 28.0 6.3 4.7 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain HSP70 PF00012.20 EMC96848.1 - 2.7e-15 55.6 0.0 6.7e-14 51.0 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 EMC96848.1 - 0.0018 18.7 0.3 0.098 13.1 0.0 2.6 2 0 0 2 2 2 1 Cell division protein FtsA Rad21_Rec8_N PF04825.13 EMC96849.1 - 0.0091 16.2 0.2 0.023 14.8 0.2 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Lzipper-MIP1 PF14389.6 EMC96849.1 - 0.46 10.8 13.8 0.11 12.8 4.2 3.3 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 ZapB PF06005.12 EMC96849.1 - 5.6 7.5 14.8 13 6.3 7.4 3.4 2 1 1 3 3 3 0 Cell division protein ZapB MMR_HSR1 PF01926.23 EMC96850.1 - 6.6e-06 26.2 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EMC96850.1 - 0.022 14.3 0.0 9.9 5.7 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Glyco_transf_34 PF05637.12 EMC96851.1 - 2.9e-63 213.8 0.0 5.2e-63 212.9 0.0 1.4 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family LRR_4 PF12799.7 EMC96851.1 - 1.4e-08 34.9 4.2 0.5 10.9 0.1 5.3 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMC96851.1 - 4.3e-05 23.2 1.1 0.077 13.1 0.1 5.2 5 0 0 5 5 5 1 Leucine Rich repeat GATA PF00320.27 EMC96851.1 - 0.096 12.3 0.2 0.23 11.1 0.2 1.7 1 0 0 1 1 1 0 GATA zinc finger Herpes_DNAp_acc PF04929.12 EMC96851.1 - 0.85 8.5 3.7 1.4 7.8 3.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor LRR_1 PF00560.33 EMC96851.1 - 1.9 9.3 5.8 64 4.7 0.0 5.2 7 0 0 7 7 7 0 Leucine Rich Repeat RR_TM4-6 PF06459.12 EMC96851.1 - 2.6 7.8 8.7 5.2 6.8 8.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EMC96851.1 - 3.7 5.7 7.2 5.6 5.1 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein ACT_3 PF10000.9 EMC96852.1 - 5.4e-21 74.3 0.0 8.2e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 EMC96852.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 ACT domain ADH_N PF08240.12 EMC96853.1 - 3.8e-27 94.3 0.9 7e-27 93.5 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC96853.1 - 5.1e-22 78.2 1.8 7.6e-22 77.7 1.8 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC96853.1 - 2e-07 32.1 0.5 3.6e-07 31.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMC96853.1 - 0.0042 17.0 0.2 0.034 14.1 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase Methyltransf_32 PF13679.6 EMC96853.1 - 0.085 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.12 EMC96854.1 - 9.6e-25 86.6 4.5 1.7e-24 85.8 4.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC96854.1 - 6e-13 48.9 0.0 3.7e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMC96854.1 - 0.00029 20.2 0.0 0.00058 19.2 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EMC96854.1 - 0.00087 18.7 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EMC96854.1 - 0.13 12.6 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMC96854.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.12 EMC96855.1 - 1.5e-28 98.8 4.5 8.8e-28 96.4 3.1 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC96855.1 - 4.9e-24 84.8 0.3 2e-23 82.8 0.1 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMC96855.1 - 2.8e-08 33.5 0.0 4.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 EMC96855.1 - 2.1e-05 24.4 0.0 6.3e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 EMC96855.1 - 0.00013 23.0 0.1 0.00022 22.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 EMC96855.1 - 0.00067 19.9 0.1 0.0012 19.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.27 EMC96855.1 - 0.0014 19.1 0.0 0.0038 17.7 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EMC96855.1 - 0.0041 17.5 0.0 0.0078 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding PALP PF00291.25 EMC96855.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Pyr_redox_2 PF07992.14 EMC96855.1 - 0.039 13.2 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NTP_transf_3 PF12804.7 EMC96855.1 - 0.065 13.6 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 MobA-like NTP transferase domain Shikimate_DH PF01488.20 EMC96855.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EMC96855.1 - 0.15 11.3 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1345 PF07077.11 EMC96856.1 - 0.73 9.5 8.9 0.027 14.2 1.8 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) Chitin_synth_2 PF03142.15 EMC96857.1 - 4.3e-234 778.0 0.1 5.7e-234 777.6 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 EMC96857.1 - 5.1e-15 55.4 0.5 1.3e-09 38.0 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EMC96857.1 - 1.4e-13 50.5 0.5 6.7e-13 48.3 0.8 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 EMC96857.1 - 4.2e-12 46.5 0.0 1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EMC96857.1 - 1.3e-11 44.8 2.2 1.3e-11 44.8 2.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Myosin_head PF00063.21 EMC96857.1 - 1.5e-10 40.0 0.0 1.1e-09 37.1 0.0 1.9 1 1 1 2 2 2 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 EMC96857.1 - 0.00039 20.0 0.0 0.0008 18.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EMC96857.1 - 0.019 14.8 0.0 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 EMC96859.1 - 1e-245 816.4 0.3 1.4e-245 815.9 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EMC96859.1 - 5.1e-71 239.8 0.0 2.3e-70 237.7 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 EMC96859.1 - 8e-16 58.0 0.1 3.6e-13 49.4 0.0 3.5 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EMC96859.1 - 5.7e-15 55.0 0.1 1.5e-14 53.7 0.1 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EMC96859.1 - 3.4e-12 46.7 3.8 7.8e-12 45.5 3.8 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMC96859.1 - 2.2e-10 40.8 0.1 1.3e-09 38.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMC96859.1 - 0.0012 18.7 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_22 PF13401.6 EMC96859.1 - 0.021 15.1 0.2 0.077 13.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EMC96859.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 EMC96859.1 - 0.039 13.7 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EMC96859.1 - 0.046 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 EMC96859.1 - 0.077 13.1 0.0 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EMC96859.1 - 0.17 11.7 0.0 0.46 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TLP1_add_C PF18313.1 EMC96860.1 - 3.4e-30 103.8 0.1 4.8e-29 100.1 0.1 2.3 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain adh_short PF00106.25 EMC96861.1 - 2e-37 128.6 0.3 3.2e-37 127.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96861.1 - 4e-34 118.2 0.1 1.4e-33 116.4 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC96861.1 - 7e-08 32.6 3.5 8e-08 32.4 0.3 2.2 1 1 0 2 2 2 1 KR domain Amidase PF01425.21 EMC96862.1 - 8.8e-97 324.9 0.0 2.1e-96 323.7 0.0 1.5 1 1 0 1 1 1 1 Amidase Palm_thioest PF02089.15 EMC96863.1 - 7.3e-72 242.1 0.0 8.4e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF4210 PF13915.6 EMC96865.1 - 9.8e-34 115.8 0.1 2.1e-33 114.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EMC96865.1 - 8.7e-23 80.2 0.4 2.5e-22 78.8 0.4 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 EMC96866.1 - 0.14 12.2 23.4 0.46 10.5 23.4 1.7 1 1 0 1 1 1 0 rRNA processing Sec62 PF03839.16 EMC96867.1 - 1.3e-74 250.3 4.6 1.3e-74 250.3 4.6 2.2 2 0 0 2 2 2 1 Translocation protein Sec62 Hydin_ADK PF17213.3 EMC96867.1 - 0.062 13.6 8.0 1.4 9.2 0.3 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain ANAPC_CDC26 PF10471.9 EMC96867.1 - 0.1 13.4 19.5 0.78 10.6 10.8 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 EMC96867.1 - 0.71 10.9 4.8 33 5.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) MPM1 PF17234.2 EMC96867.1 - 1.6 8.9 7.3 1.2 9.3 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PEHE PF15275.6 EMC96867.1 - 1.9 9.1 6.1 8.4 7.0 1.6 2.6 2 0 0 2 2 2 0 PEHE domain TFIIA PF03153.13 EMC96867.1 - 9.6 6.1 21.3 0.53 10.2 15.2 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L11_N PF03946.14 EMC96868.1 - 1.2e-23 82.7 0.1 1.9e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EMC96868.1 - 3.1e-15 56.4 0.5 5.3e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HET PF06985.11 EMC96869.1 - 1.4e-19 70.9 0.0 1.7e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 EMC96870.1 - 4.1e-26 91.8 40.3 5.1e-26 91.4 40.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EMC96870.1 - 3.5e-07 29.8 16.9 1e-06 28.4 16.9 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EMC96871.1 - 1.1e-83 281.6 24.3 1.4e-83 281.3 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC96871.1 - 4.8e-25 88.2 50.1 9.7e-24 83.9 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMC96871.1 - 4.4e-05 22.1 2.4 4.4e-05 22.1 2.4 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_43 PF04616.14 EMC96872.1 - 1.9e-76 257.1 0.3 3.2e-76 256.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EMC96872.1 - 1.4e-12 47.8 0.0 2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Zn_clus PF00172.18 EMC96873.1 - 7e-10 38.9 7.5 1.3e-09 38.0 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC96873.1 - 1.6e-06 27.4 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 EMC96873.1 - 0.062 13.1 2.0 0.13 12.0 2.0 1.5 1 0 0 1 1 1 0 Integrin plexin domain MiaE_2 PF13794.6 EMC96875.1 - 0.098 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Pho88 PF10032.9 EMC96876.1 - 3e-39 134.2 0.2 9.9e-39 132.5 0.2 1.6 1 1 0 1 1 1 1 Phosphate transport (Pho88) ThiF PF00899.21 EMC96878.1 - 4.1e-28 98.4 0.0 5.5e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family LIDHydrolase PF10230.9 EMC96879.1 - 1.2e-44 152.9 0.0 4.3e-37 128.1 0.0 2.3 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EMC96879.1 - 0.0063 17.2 0.8 0.023 15.3 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC96879.1 - 0.041 13.2 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ribosomal_S3Ae PF01015.18 EMC96880.1 - 5.5e-88 293.8 2.7 6.8e-88 293.5 2.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Ham1p_like PF01725.16 EMC96881.1 - 3.2e-61 206.5 0.0 3.5e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 EMC96882.1 - 8e-27 94.3 0.5 1.4e-26 93.6 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EMC96882.1 - 1.6e-06 28.5 0.1 9e-06 26.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EMC96882.1 - 3.6e-05 24.0 0.0 0.00075 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMC96882.1 - 5.4e-05 23.5 0.0 9.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMC96882.1 - 0.00053 20.3 0.0 0.0009 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EMC96882.1 - 0.0012 19.3 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 EMC96882.1 - 0.0022 17.9 0.8 0.83 9.5 0.0 2.2 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_16 PF13191.6 EMC96882.1 - 0.0057 17.1 0.0 0.0098 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Hydin_ADK PF17213.3 EMC96882.1 - 0.0057 17.0 0.0 0.0098 16.2 0.0 1.4 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain ADK PF00406.22 EMC96882.1 - 0.0082 16.3 0.0 0.32 11.1 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase SKI PF01202.22 EMC96882.1 - 0.0085 16.2 0.0 0.031 14.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate kinase AAA_24 PF13479.6 EMC96882.1 - 0.0093 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMC96882.1 - 0.0095 15.4 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_25 PF13481.6 EMC96882.1 - 0.012 15.2 0.0 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EMC96882.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Hpr_kinase_C PF07475.12 EMC96882.1 - 0.02 14.4 0.1 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NTPase_1 PF03266.15 EMC96882.1 - 0.022 14.7 1.2 0.022 14.7 1.2 1.9 2 1 0 2 2 2 0 NTPase NACHT PF05729.12 EMC96882.1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EMC96882.1 - 0.033 14.2 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EMC96882.1 - 0.048 13.6 0.2 0.091 12.7 0.0 1.5 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_19 PF13245.6 EMC96882.1 - 0.05 13.9 0.1 0.089 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EMC96882.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EMC96882.1 - 0.072 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TraI_2B PF18340.1 EMC96882.1 - 0.09 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain MMR_HSR1 PF01926.23 EMC96882.1 - 0.094 12.8 0.1 0.16 12.1 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EMC96882.1 - 0.098 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EMC96882.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EMC96882.1 - 0.14 11.8 0.2 12 5.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase FtsK_SpoIIIE PF01580.18 EMC96882.1 - 0.14 11.5 0.1 0.3 10.4 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 EMC96882.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.22 EMC96882.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Abhydrolase_1 PF00561.20 EMC96883.1 - 3e-26 92.6 0.0 7.8e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC96883.1 - 1e-13 52.5 0.0 1.4e-13 51.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC96883.1 - 1.7e-08 34.0 0.0 4.9e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EMC96883.1 - 2.7e-07 30.5 0.2 0.023 14.4 0.0 2.1 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 EMC96883.1 - 4.4e-05 23.7 0.0 7.1e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.11 EMC96883.1 - 0.00018 20.6 0.0 0.00046 19.3 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase DUF676 PF05057.14 EMC96883.1 - 0.00035 20.2 0.0 0.00053 19.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EMC96883.1 - 0.0026 17.6 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 EMC96883.1 - 0.003 16.5 0.0 0.0064 15.4 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF915 PF06028.11 EMC96883.1 - 0.0043 16.4 0.0 2.1 7.6 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 EMC96883.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 EMC96883.1 - 0.045 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase UPF0227 PF05728.12 EMC96883.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_2 PF01674.18 EMC96883.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Nitr_red_bet_C PF14711.6 EMC96883.1 - 0.16 11.7 0.1 0.52 10.0 0.0 1.8 1 1 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal DUF3530 PF12048.8 EMC96883.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) His_Phos_2 PF00328.22 EMC96884.1 - 3.7e-09 36.4 0.0 2.7e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) CorA PF01544.18 EMC96885.1 - 5.8e-41 140.7 0.0 1e-40 139.9 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AIMP2_LysRS_bd PF16780.5 EMC96886.1 - 0.068 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain SPC12 PF06645.13 EMC96887.1 - 3.2e-31 107.2 0.5 3.7e-31 107.0 0.5 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) zf-rbx1 PF12678.7 EMC96888.1 - 4.9e-25 87.6 12.9 6.9e-25 87.1 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EMC96888.1 - 3.7e-17 62.2 10.1 4.9e-17 61.8 10.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EMC96888.1 - 3.5e-06 27.2 14.9 0.00013 22.2 14.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMC96888.1 - 8.3e-05 22.4 3.5 8.3e-05 22.4 3.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC96888.1 - 0.0016 18.3 11.5 0.021 14.7 11.5 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMC96888.1 - 0.27 11.0 15.4 22 4.9 15.4 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 EMC96888.1 - 0.36 10.7 10.8 1.1 9.2 4.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC96888.1 - 0.53 10.3 7.8 1.9 8.6 7.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 EMC96888.1 - 0.55 10.4 9.2 2.8 8.2 9.4 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EMC96888.1 - 0.8 9.4 14.7 0.19 11.4 5.0 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EMC96888.1 - 9.9 6.2 11.7 65 3.6 11.7 2.4 1 1 0 1 1 1 0 zinc-RING finger domain PNRC PF15365.6 EMC96889.1 - 1.4e-08 34.3 4.0 1.4e-08 34.3 4.0 4.5 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator motif FA_hydroxylase PF04116.13 EMC96890.1 - 3.8e-25 88.8 15.3 3.8e-25 88.8 15.3 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily bVLRF1 PF18826.1 EMC96890.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor PDR_CDR PF06422.12 EMC96890.1 - 2.7 8.0 8.0 15 5.6 2.0 3.1 3 0 0 3 3 3 0 CDR ABC transporter PLDc_2 PF13091.6 EMC96891.1 - 1.5e-13 50.8 0.0 6e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EMC96891.1 - 4.1e-07 29.9 4.5 0.0077 16.4 0.5 3.6 3 1 0 3 3 3 2 Phospholipase D Active site motif DUF3828 PF12883.7 EMC96891.1 - 0.026 14.9 0.0 5.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3828) NDUFA12 PF05071.16 EMC96892.1 - 1e-07 32.7 1.7 1.1e-07 32.6 1.7 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ABC_membrane PF00664.23 EMC96893.1 - 4e-56 190.7 28.4 1.9e-35 122.9 6.2 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMC96893.1 - 8.1e-52 175.4 0.0 6.5e-31 107.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMC96893.1 - 1.5e-07 31.1 2.0 0.16 11.4 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMC96893.1 - 2.2e-07 31.0 0.1 0.0043 16.9 0.1 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMC96893.1 - 2.1e-05 25.1 0.8 0.012 16.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EMC96893.1 - 2.3e-05 24.7 0.2 1.9 8.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EMC96893.1 - 8.5e-05 22.5 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMC96893.1 - 9.6e-05 22.4 0.5 0.073 13.2 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EMC96893.1 - 0.0002 21.8 0.1 1.3 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EMC96893.1 - 0.00036 20.7 0.5 0.064 13.4 0.0 2.9 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_29 PF13555.6 EMC96893.1 - 0.00079 19.1 0.5 0.4 10.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 EMC96893.1 - 0.003 16.7 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EMC96893.1 - 0.0058 16.4 0.0 5 6.8 0.0 2.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 EMC96893.1 - 0.0085 16.5 0.3 6.9 7.1 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EMC96893.1 - 0.0098 16.0 1.1 2 8.4 0.1 2.8 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 EMC96893.1 - 0.0099 15.5 0.3 2.7 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EMC96893.1 - 0.026 14.2 0.2 0.2 11.3 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain CbiA PF01656.23 EMC96893.1 - 0.033 14.2 0.4 0.28 11.3 0.0 2.6 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EMC96893.1 - 0.043 14.0 0.0 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EMC96893.1 - 0.057 13.2 0.2 38 4.0 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 EMC96893.1 - 0.058 12.9 0.1 11 5.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EMC96893.1 - 0.06 13.1 0.1 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMC96893.1 - 0.09 12.5 1.5 9.5 5.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EMC96893.1 - 0.1 13.0 0.2 34 4.9 0.0 3.3 4 0 0 4 4 2 0 RNA helicase Zeta_toxin PF06414.12 EMC96893.1 - 0.11 11.7 1.1 7.3 5.8 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin TIP49 PF06068.13 EMC96893.1 - 0.12 11.6 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 EMC96893.1 - 0.16 12.5 0.7 51 4.4 0.0 3.4 4 0 0 4 4 2 0 AAA domain AAA_5 PF07728.14 EMC96893.1 - 0.19 11.7 2.8 19 5.3 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 EMC96893.1 - 0.21 10.9 1.0 4.1 6.7 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family NACHT PF05729.12 EMC96893.1 - 0.29 11.0 1.3 6.5 6.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 EMC96893.1 - 0.39 10.3 2.1 2 8.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EMC96893.1 - 1.9 8.7 4.7 22 5.3 0.1 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase RPA_interact_M PF14767.6 EMC96894.1 - 0.11 13.1 0.1 0.11 13.1 0.1 1.8 2 0 0 2 2 2 0 Replication protein A interacting middle Bacteriocin_IIc PF10439.9 EMC96894.1 - 0.42 10.8 5.1 0.19 11.9 3.1 1.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide SUIM_assoc PF16619.5 EMC96894.1 - 0.84 9.8 7.2 1.3 9.1 7.2 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SOR_SNZ PF01680.17 EMC96895.1 - 2.7e-107 357.2 6.4 3.7e-107 356.8 6.4 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EMC96895.1 - 1.4e-06 27.8 11.6 5.2e-06 25.9 0.9 2.6 2 2 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EMC96895.1 - 0.0001 21.6 0.3 0.029 13.5 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 EMC96895.1 - 0.00012 21.4 0.3 0.0025 17.0 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 EMC96895.1 - 0.00086 19.3 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 EMC96895.1 - 0.006 16.1 0.3 0.044 13.2 0.0 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 EMC96895.1 - 0.0072 15.5 0.1 0.15 11.2 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.15 EMC96895.1 - 0.07 12.5 5.9 0.17 11.2 0.3 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase Zn_clus PF00172.18 EMC96897.1 - 1.8e-09 37.6 9.7 3.6e-09 36.6 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC96897.1 - 4.7e-06 25.8 0.8 8e-06 25.1 0.2 1.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain TPR_19 PF14559.6 EMC96897.1 - 0.086 13.4 1.2 0.19 12.3 1.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1275 PF06912.11 EMC96898.1 - 5.1e-43 147.2 17.9 5.9e-43 147.0 17.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Sugar_tr PF00083.24 EMC96899.1 - 1.6e-95 320.6 31.0 2e-95 320.3 31.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC96899.1 - 2.5e-19 69.4 31.9 2.5e-19 69.4 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.22 EMC96900.1 - 1.9e-37 128.5 0.0 2.6e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Flu_NP PF00506.18 EMC96900.1 - 0.23 10.1 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein Fungal_trans_2 PF11951.8 EMC96901.1 - 3.5e-22 78.8 0.7 5e-22 78.3 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_MalT PF17874.1 EMC96901.1 - 0.041 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 MalT-like TPR region 2-Hacid_dh_C PF02826.19 EMC96902.1 - 1.6e-38 131.9 0.0 2.1e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMC96902.1 - 4.2e-11 42.6 0.0 5.9e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMC96902.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.16 EMC96903.1 - 1.9e-41 142.2 26.2 2.8e-41 141.6 26.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Capsid_NCLDV PF04451.12 EMC96903.1 - 0.18 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein DUF3176 PF11374.8 EMC96904.1 - 1.9e-26 92.3 0.7 6.3e-26 90.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) EI24 PF07264.11 EMC96904.1 - 0.0012 19.2 2.3 0.0012 19.2 2.3 1.9 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) MaoC_dehydratas PF01575.19 EMC96905.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain eRF1_2 PF03464.15 EMC96908.1 - 1.8e-47 161.0 0.1 2.8e-47 160.4 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EMC96908.1 - 3e-39 134.0 0.4 8.5e-39 132.5 0.2 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 EMC96908.1 - 2.2e-21 76.2 0.0 3.4e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EMC96908.1 - 2.1e-10 41.0 0.0 3.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EMC96908.1 - 8.2e-09 35.8 0.0 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Rad50_zn_hook PF04423.14 EMC96908.1 - 4.4 7.2 6.4 44 4.0 0.0 3.8 4 0 0 4 4 4 0 Rad50 zinc hook motif Aa_trans PF01490.18 EMC96909.1 - 3.5e-66 223.6 23.5 4.1e-66 223.4 23.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EMC96909.1 - 0.0023 17.0 9.3 0.0023 17.0 9.3 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family PDT PF00800.18 EMC96910.1 - 1e-61 207.9 0.0 1.5e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EMC96910.1 - 2.8e-06 27.0 0.0 7e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain Histone PF00125.24 EMC96911.1 - 2e-16 60.5 0.0 2.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EMC96911.1 - 1.3e-12 47.2 0.1 2.9e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EMC96911.1 - 1.5e-05 25.2 0.0 2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CN_hydrolase PF00795.22 EMC96912.1 - 3.2e-18 66.0 0.0 2.7e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Ribosomal_L39 PF00832.20 EMC96913.1 - 1.9e-21 75.4 9.4 2.1e-21 75.2 9.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein T5orf172 PF10544.9 EMC96916.1 - 1.6e-24 86.4 0.3 4.9e-24 84.8 0.3 1.8 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EMC96916.1 - 1.3e-22 80.3 0.6 1.3e-22 80.3 0.6 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 zf-C4pol PF14260.6 EMC96916.1 - 0.034 14.6 2.0 0.2 12.1 0.4 2.5 1 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta GSH_synth_ATP PF03917.17 EMC96918.1 - 1e-133 445.8 0.0 1.2e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EMC96918.1 - 4.1e-33 113.9 0.0 6.7e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 EMC96919.1 - 1.2e-41 142.7 0.0 1.8e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC96919.1 - 1.1e-18 67.6 0.0 2.2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC96919.1 - 7.5e-07 29.3 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMC96919.1 - 0.0014 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EMC96919.1 - 0.0086 15.8 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 2 SWI2/SNF2 ATPase Glyco_transf_8 PF01501.20 EMC96920.1 - 4.5e-09 36.2 4.6 2.4e-08 33.9 4.6 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 AAA PF00004.29 EMC96921.1 - 8.5e-41 139.5 0.0 1.5e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMC96921.1 - 2.4e-10 40.0 0.8 5e-10 39.0 0.8 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EMC96921.1 - 1.2e-09 37.9 0.1 2.5e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EMC96921.1 - 2.2e-06 28.0 0.2 0.021 15.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 EMC96921.1 - 8.8e-06 25.9 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EMC96921.1 - 1.3e-05 24.5 0.0 2.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EMC96921.1 - 0.00011 22.2 0.0 0.00033 20.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC96921.1 - 0.00016 22.1 0.4 0.0019 18.6 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EMC96921.1 - 0.00032 20.5 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EMC96921.1 - 0.0026 17.6 0.0 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EMC96921.1 - 0.0028 17.9 0.4 0.0076 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMC96921.1 - 0.0045 17.5 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EMC96921.1 - 0.011 15.9 0.1 0.027 14.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 EMC96921.1 - 0.015 14.6 0.1 0.52 9.6 0.1 2.2 1 1 0 2 2 2 0 KaiC TIP49 PF06068.13 EMC96921.1 - 0.017 14.3 0.1 0.041 13.1 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EMC96921.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EMC96921.1 - 0.027 14.4 0.2 0.56 10.1 0.2 2.4 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EMC96921.1 - 0.029 14.4 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMC96921.1 - 0.057 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EMC96921.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EMC96921.1 - 0.068 12.7 1.3 0.61 9.6 0.4 2.6 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMC96921.1 - 0.073 12.3 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 EMC96921.1 - 0.093 12.2 0.5 0.52 9.7 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 EMC96921.1 - 0.15 11.7 0.3 0.32 10.7 0.3 1.6 1 1 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 EMC96921.1 - 0.17 11.6 0.5 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain ABC_tran PF00005.27 EMC96921.1 - 0.18 12.3 0.2 0.87 10.1 0.2 2.2 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 EMC96921.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UQ_con PF00179.26 EMC96922.1 - 7.9e-42 142.2 0.0 1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EMC96922.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain RWD PF05773.22 EMC96922.1 - 0.08 13.2 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain UBA PF00627.31 EMC96922.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 UBA/TS-N domain U79_P34 PF03064.16 EMC96922.1 - 0.33 10.3 1.7 0.47 9.8 1.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ribosomal_L5_C PF00673.21 EMC96924.1 - 3.6e-27 94.4 0.0 7e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EMC96924.1 - 1.7e-13 50.6 0.2 2.9e-13 49.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 SAC3_GANP PF03399.16 EMC96925.1 - 3.1e-103 345.2 0.3 3.6e-103 345.0 0.3 1.0 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EMC96925.1 - 0.0043 17.0 0.1 0.038 14.0 0.1 2.3 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family DUF1138 PF06592.13 EMC96925.1 - 0.16 12.0 1.5 1.5 8.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1138) adh_short PF00106.25 EMC96926.1 - 3.4e-31 108.2 0.0 4.6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC96926.1 - 1.7e-16 60.5 0.0 2.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EMC96926.1 - 0.0053 15.9 0.0 0.0074 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EMC96926.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF4203 PF13886.6 EMC96928.1 - 4.3e-56 189.8 31.7 5.4e-56 189.5 31.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2423 PF10338.9 EMC96929.1 - 2.9e-18 65.8 4.8 2.9e-18 65.8 4.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) PINIT PF14324.6 EMC96930.1 - 1.4e-41 142.2 0.6 2.3e-41 141.5 0.6 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EMC96930.1 - 3.7e-18 65.0 1.3 5.8e-18 64.4 1.3 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 EMC96930.1 - 1e-07 31.5 0.4 1.9e-07 30.7 0.4 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 EMC96930.1 - 3.2e-07 30.1 0.5 5.9e-07 29.2 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ABC_membrane PF00664.23 EMC96931.1 - 1.1e-79 268.0 25.1 8.7e-41 140.4 7.8 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EMC96931.1 - 7.2e-51 172.3 0.0 2.7e-30 105.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMC96931.1 - 9.7e-09 35.0 4.8 0.0043 16.5 0.2 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMC96931.1 - 5.5e-05 23.6 1.3 0.066 13.6 0.4 3.2 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMC96931.1 - 0.00011 22.1 0.1 0.051 13.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMC96931.1 - 0.00033 20.7 6.0 0.18 11.9 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 EMC96931.1 - 0.0012 19.0 1.0 0.094 12.8 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 EMC96931.1 - 0.0013 18.4 0.3 2.3 8.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 EMC96931.1 - 0.0075 16.4 1.2 1.7 8.7 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 EMC96931.1 - 0.013 15.3 0.1 5 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EMC96931.1 - 0.032 14.7 0.2 5.4 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EMC96931.1 - 0.035 13.8 0.8 3.5 7.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 EMC96931.1 - 0.045 14.0 1.2 44 4.3 0.0 4.1 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 EMC96931.1 - 0.1 12.3 0.7 3.1 7.5 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_22 PF13401.6 EMC96931.1 - 0.3 11.4 4.6 10 6.4 0.1 3.3 2 1 0 2 2 2 0 AAA domain DUF2841 PF11001.8 EMC96933.1 - 1.4e-30 105.9 0.5 2.9e-30 104.9 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Dioxygenase_C PF00775.21 EMC96934.1 - 2.5e-42 144.4 0.1 3.9e-42 143.8 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EMC96934.1 - 8.2e-22 76.9 0.0 2.2e-21 75.5 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus SpaA PF17802.1 EMC96934.1 - 0.0019 18.5 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 EMC96934.1 - 0.01 16.1 0.0 0.078 13.3 0.0 2.3 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Cu_amine_oxid PF01179.20 EMC96935.1 - 6.9e-162 539.0 0.1 8.3e-162 538.8 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EMC96935.1 - 3.5e-22 78.7 0.6 1.3e-21 76.9 0.1 2.3 3 0 0 3 3 3 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EMC96935.1 - 1.6e-09 37.8 0.0 2.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sulfatase PF00884.23 EMC96936.1 - 2.2e-76 257.2 0.0 2.8e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 EMC96936.1 - 0.0015 19.3 0.0 0.058 14.1 0.0 2.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 EMC96936.1 - 0.029 14.0 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EMC96936.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF4994 PF16385.5 EMC96936.1 - 0.1 12.5 0.1 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF229 PF02995.17 EMC96936.1 - 0.15 10.6 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) BAR PF03114.18 EMC96937.1 - 1.2e-42 146.2 9.7 9.3e-40 136.8 2.2 2.1 2 0 0 2 2 2 2 BAR domain CP12 PF02672.15 EMC96937.1 - 0.0069 17.1 0.1 0.02 15.6 0.0 1.9 2 0 0 2 2 2 1 CP12 domain KfrA_N PF11740.8 EMC96937.1 - 0.043 14.5 1.7 0.11 13.2 0.1 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DRAT PF07357.11 EMC96937.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) DUF2884 PF11101.8 EMC96937.1 - 0.38 10.2 4.3 8.1 5.9 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Peptidase_M22 PF00814.25 EMC96938.1 - 5.5e-86 288.6 0.0 6.6e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family TOM13 PF08219.11 EMC96938.1 - 0.021 14.8 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Outer membrane protein TOM13 Carbam_trans_N PF02543.15 EMC96938.1 - 0.13 11.9 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus ACOX PF01756.19 EMC96940.1 - 3.5e-46 157.0 0.8 5.8e-46 156.3 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EMC96940.1 - 6.3e-26 91.4 0.1 1.7e-25 90.0 0.1 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EMC96940.1 - 4.1e-12 46.1 0.0 8.4e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EMC96940.1 - 1.3e-06 28.7 0.1 0.018 15.3 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Ndc1_Nup PF09531.10 EMC96941.1 - 2.3e-172 574.9 0.8 2.5e-172 574.8 0.8 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 EMC96942.1 - 6.1e-24 84.3 0.5 6.1e-24 84.3 0.5 2.9 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EMC96942.1 - 6.3e-15 54.9 3.0 1.1e-14 54.2 1.8 2.0 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.21 EMC96942.1 - 0.00041 20.1 0.3 0.0013 18.4 0.3 1.9 1 0 0 1 1 1 1 Synaptobrevin Syntaxin PF00804.25 EMC96942.1 - 0.012 15.3 18.9 0.0095 15.6 13.3 3.1 2 1 0 2 2 2 0 Syntaxin MPS2 PF17060.5 EMC96942.1 - 0.048 12.9 2.4 0.049 12.9 1.0 1.8 1 1 1 2 2 2 0 Monopolar spindle protein 2 Prominin PF05478.11 EMC96942.1 - 0.064 11.2 4.9 0.079 10.9 4.2 1.5 1 1 0 1 1 1 0 Prominin Orf78 PF06024.12 EMC96942.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.1 2 1 0 2 2 2 0 Orf78 (ac78) Amnionless PF14828.6 EMC96942.1 - 0.22 10.3 3.9 0.33 9.7 3.9 1.5 1 1 0 1 1 1 0 Amnionless DUF812 PF05667.11 EMC96942.1 - 1.1 8.1 15.1 0.97 8.2 13.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 EMC96942.1 - 2.8 8.0 7.1 19 5.3 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EMC96942.1 - 5 7.1 10.2 1.7 8.7 0.7 3.1 2 1 1 3 3 3 0 Laminin Domain II Epimerase PF01370.21 EMC96944.1 - 7.8e-17 61.5 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC96944.1 - 1e-12 48.3 0.0 1.7e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC96944.1 - 6.4e-11 42.3 0.3 1e-10 41.6 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EMC96944.1 - 9.6e-08 31.3 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMC96944.1 - 1.4e-07 31.0 0.0 3.5e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EMC96944.1 - 2.5e-07 30.1 0.1 3.8e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EMC96944.1 - 1.8e-05 24.3 0.5 4.6e-05 22.9 0.5 1.8 1 1 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EMC96944.1 - 6.3e-05 22.5 0.0 8.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EMC96944.1 - 0.014 15.3 0.4 0.05 13.5 0.4 1.9 1 1 0 1 1 1 0 KR domain 3HCDH_N PF02737.18 EMC96944.1 - 0.049 13.5 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EMC96944.1 - 0.062 13.9 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EMC96944.1 - 0.079 12.1 0.0 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Tcf25 PF04910.14 EMC96945.1 - 2.7e-71 240.5 0.0 3.5e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Nop53 PF07767.11 EMC96945.1 - 0.093 12.1 14.6 0.18 11.1 14.6 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF1387 PF07139.11 EMC96945.1 - 2.6 7.7 8.1 0.065 13.0 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Stm1_N PF09598.10 EMC96945.1 - 6.7 7.6 16.2 0.48 11.3 9.1 2.7 2 0 0 2 2 2 0 Stm1 FAA_hydrolase PF01557.18 EMC96946.1 - 1.4e-63 214.5 0.0 2.9e-63 213.5 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 EMC96946.1 - 4.3e-18 65.9 0.1 4.9e-16 59.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC96946.1 - 1.2e-17 65.3 0.0 2.3e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_1 PF01979.20 EMC96946.1 - 1.6e-17 63.9 0.5 2.4e-17 63.3 0.5 1.3 1 0 0 1 1 1 1 Amidohydrolase family Hydrolase_4 PF12146.8 EMC96946.1 - 2.3e-16 59.8 0.0 6.3e-16 58.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Amidohydro_3 PF07969.11 EMC96946.1 - 6.2e-08 32.5 2.2 9.9e-05 22.0 0.5 3.8 2 1 0 2 2 2 2 Amidohydrolase family Ser_hydrolase PF06821.13 EMC96946.1 - 9.6e-05 22.3 0.1 0.00081 19.3 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.12 EMC96946.1 - 0.0025 17.4 0.0 0.02 14.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Ndr PF03096.14 EMC96946.1 - 0.0028 16.4 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_8 PF06259.12 EMC96946.1 - 0.025 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase LCAT PF02450.15 EMC96946.1 - 0.086 12.0 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_4 PF08386.10 EMC96946.1 - 0.096 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.13 EMC96946.1 - 0.11 12.2 0.3 0.34 10.6 0.3 1.7 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EMC96946.1 - 0.16 11.8 0.0 5.6 6.7 0.0 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase family Aa_trans PF01490.18 EMC96947.1 - 2e-42 145.4 32.9 2.5e-42 145.0 32.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EMC96947.1 - 0.0015 17.7 19.3 0.0015 17.7 19.3 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AhpC-TSA PF00578.21 EMC96948.1 - 1.4e-23 83.2 0.0 2.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMC96948.1 - 6.5e-16 58.4 0.0 1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EMC96948.1 - 0.0011 19.0 0.0 0.0028 17.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Hist_deacetyl PF00850.19 EMC96949.1 - 0.042 13.3 1.0 0.05 13.1 1.0 1.1 1 0 0 1 1 1 0 Histone deacetylase domain UCH PF00443.29 EMC96952.1 - 1.2e-15 57.7 0.0 5.3e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC96952.1 - 4.3e-13 49.5 0.0 4.3e-10 39.7 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.27 EMC96953.1 - 4.7e-66 218.8 2.2 7e-22 77.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro_3_hydrox_C PF05373.11 EMC96954.1 - 0.0062 16.6 0.1 3.4 7.8 0.0 2.1 2 0 0 2 2 2 2 L-proline 3-hydroxylase, C-terminal DUF3863 PF12979.7 EMC96954.1 - 0.047 12.5 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) SnoaL_3 PF13474.6 EMC96954.1 - 0.048 13.9 2.1 0.082 13.2 2.1 1.4 1 1 0 1 1 1 0 SnoaL-like domain Peptidase_S9 PF00326.21 EMC96955.1 - 4.1e-37 127.7 0.0 6.9e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.14 EMC96955.1 - 3.9e-06 26.4 0.6 0.05 12.9 0.4 2.3 2 0 0 2 2 2 2 Secretory lipase Peptidase_S15 PF02129.18 EMC96955.1 - 7.1e-06 25.8 0.2 1.1e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EMC96955.1 - 8.1e-05 23.3 8.8 0.0029 18.2 10.1 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.12 EMC96955.1 - 0.00011 22.0 0.0 0.0075 16.2 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 EMC96955.1 - 0.00048 19.9 0.1 0.0067 16.1 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 EMC96955.1 - 0.00052 19.6 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EMC96955.1 - 0.0016 17.7 0.4 0.12 11.6 0.4 2.4 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EMC96955.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 EMC96955.1 - 0.14 10.8 0.2 1.5 7.4 0.2 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) CH PF00307.31 EMC96956.1 - 5.2e-47 158.5 0.2 3e-22 78.9 0.3 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EMC96956.1 - 1.1e-24 86.3 0.1 3.1e-24 84.8 0.1 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EMC96956.1 - 9.8e-09 34.9 1.0 0.0013 18.5 0.1 3.2 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_8 PF13833.6 EMC96956.1 - 0.0035 17.2 0.1 0.082 12.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EMC96956.1 - 0.0043 16.9 0.1 0.038 13.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EMC96956.1 - 0.013 15.1 0.1 0.61 9.8 0.0 2.7 2 0 0 2 2 2 0 EF hand CH_2 PF06294.11 EMC96956.1 - 0.013 15.6 0.0 0.065 13.4 0.1 2.3 2 0 0 2 2 1 0 CH-like domain in sperm protein zf-RRPl_C4 PF17026.5 EMC96956.1 - 0.013 15.6 0.0 0.051 13.7 0.0 2.0 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type EMP24_GP25L PF01105.24 EMC96956.1 - 0.018 15.0 0.2 0.044 13.7 0.2 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD EF-hand_7 PF13499.6 EMC96956.1 - 0.066 13.7 2.9 0.37 11.3 0.3 3.2 3 0 0 3 3 3 0 EF-hand domain pair Spectrin PF00435.21 EMC96956.1 - 0.077 13.5 7.8 0.038 14.5 2.3 2.9 3 0 0 3 3 3 0 Spectrin repeat TetR_C_24 PF17932.1 EMC96956.1 - 0.12 12.7 1.7 2 8.7 0.1 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF2884 PF11101.8 EMC96956.1 - 0.12 11.8 6.0 0.4 10.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) DegS PF05384.11 EMC96956.1 - 0.25 10.8 2.4 0.28 10.7 0.7 1.9 2 0 0 2 2 2 0 Sensor protein DegS DUF4508 PF14969.6 EMC96956.1 - 0.27 11.5 3.3 2 8.7 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) FliG_N PF14842.6 EMC96956.1 - 1.2 9.8 4.3 1.7 9.2 0.2 3.0 4 0 0 4 4 3 0 FliG N-terminal domain PBD PF00786.28 EMC96957.1 - 0.049 14.0 0.3 0.12 12.8 0.3 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain NmrA PF05368.13 EMC96959.1 - 6.6e-35 120.8 0.0 8.8e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC96959.1 - 2.4e-14 53.7 0.0 3.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMC96959.1 - 0.00012 21.4 0.0 0.00032 20.0 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EMC96959.1 - 0.0021 17.6 0.1 0.022 14.2 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EMC96959.1 - 0.014 15.9 0.7 0.83 10.3 0.0 2.8 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EMC96959.1 - 0.034 14.6 0.1 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EMC96959.1 - 0.081 13.0 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 EMC96959.1 - 0.12 11.4 0.0 4.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein WD40 PF00400.32 EMC96961.1 - 3.6e-14 52.9 13.9 0.0036 18.1 0.4 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC96961.1 - 0.00062 20.0 0.0 0.8 10.0 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain MraZ PF02381.18 EMC96961.1 - 0.0024 17.8 0.0 0.96 9.5 0.0 2.5 2 0 0 2 2 2 1 MraZ protein, putative antitoxin-like Cwf_Cwc_15 PF04889.12 EMC96961.1 - 0.035 13.8 18.8 0.073 12.8 18.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 EMC96961.1 - 0.12 12.0 2.0 0.17 11.5 2.0 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 EMC96961.1 - 0.2 10.8 21.4 0.43 9.7 21.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EMC96961.1 - 0.25 10.6 19.3 0.4 9.9 19.3 1.2 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 EMC96961.1 - 0.55 8.7 5.4 0.74 8.3 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.11 EMC96961.1 - 1.8 8.6 7.0 4.3 7.3 7.0 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2796 PF10986.8 EMC96961.1 - 2.8 7.9 6.7 5 7.1 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SDA1 PF05285.12 EMC96961.1 - 3.5 7.0 12.6 6.5 6.1 12.6 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EMC96961.1 - 3.7 5.5 19.4 5.4 5.0 19.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EMC96961.1 - 3.9 5.6 14.9 6 4.9 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L23eN PF03939.13 EMC96962.1 - 1.7e-25 88.9 9.1 3.3e-25 88.0 9.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EMC96962.1 - 1e-14 54.7 2.4 1.1e-14 54.5 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.15 EMC96963.1 - 1.6e-23 82.1 2.2 1.9e-23 81.9 2.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger NAP PF00956.18 EMC96964.1 - 1.9e-96 322.4 12.4 1.9e-96 322.4 12.4 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nucleo_P87 PF07267.11 EMC96964.1 - 3.4 6.4 15.1 1.2 7.9 2.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RNA_pol_3_Rpc31 PF11705.8 EMC96964.1 - 4.9 7.4 32.1 2.3 8.4 22.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 UFD1 PF03152.14 EMC96965.1 - 6.3e-73 243.9 0.0 7.9e-73 243.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EMC96965.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Bmt2 PF11968.8 EMC96966.1 - 5.9e-88 294.4 0.0 7.9e-88 294.0 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Promethin PF16015.5 EMC96967.1 - 4.5e-27 94.1 17.9 5.7e-27 93.7 17.9 1.1 1 0 0 1 1 1 1 Promethin FA_desaturase PF00487.24 EMC96967.1 - 3.8 7.3 6.0 6.2 6.6 6.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase RNA_pol_I_A49 PF06870.12 EMC96968.1 - 6.7e-81 272.1 0.6 7.8e-81 271.9 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SLATT_fungal PF18142.1 EMC96969.1 - 6e-34 116.6 0.9 8e-34 116.2 0.9 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain LOR PF04525.12 EMC96970.1 - 6.9e-08 32.3 0.0 9.2e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 LURP-one-related PKcGMP_CC PF16808.5 EMC96970.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF676 PF05057.14 EMC96971.1 - 9.6e-06 25.3 0.0 1.2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EMC96971.1 - 0.0011 18.8 0.0 0.0017 18.1 0.0 1.4 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EMC96971.1 - 0.0027 18.3 0.0 0.0033 18.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC96971.1 - 0.081 12.2 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EMC96971.1 - 0.098 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 EMC96971.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ank_2 PF12796.7 EMC96972.1 - 3.8e-18 65.9 0.3 6.2e-14 52.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC96972.1 - 6.7e-18 64.8 0.0 5e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMC96972.1 - 1e-11 44.8 0.2 2.9e-06 27.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EMC96972.1 - 1.4e-10 41.2 2.4 0.0001 22.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EMC96972.1 - 1.7e-09 37.1 0.0 4.9e-05 23.4 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat GhoS PF11080.8 EMC96972.1 - 0.13 12.2 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Endoribonuclease GhoS Ank_2 PF12796.7 EMC96973.1 - 2.7e-17 63.1 0.6 1.3e-08 35.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EMC96973.1 - 1.7e-11 44.1 0.2 1.6e-05 25.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EMC96973.1 - 9.4e-11 41.8 0.4 3.2e-09 36.8 0.1 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMC96973.1 - 2.1e-09 37.7 0.1 5.5e-06 26.8 0.1 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC96973.1 - 2.9e-07 30.2 0.1 0.1 13.2 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat MFS_1 PF07690.16 EMC96974.1 - 3.2e-31 108.6 41.3 3.2e-31 108.6 41.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PhyH PF05721.13 EMC96978.1 - 7.8e-10 39.4 0.1 2.1e-09 38.0 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DNA_binding_1 PF01035.20 EMC96979.1 - 8.7e-24 83.5 0.0 1e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Pet127 PF08634.10 EMC96984.1 - 4.1e-118 393.8 0.7 5.4e-118 393.4 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 ARD PF03079.14 EMC96985.1 - 1.8e-45 154.9 0.0 2.1e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EMC96985.1 - 1.6e-09 37.3 0.1 2.5e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EMC96985.1 - 1.7e-05 24.7 0.1 2.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EMC96985.1 - 0.0047 16.5 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EMC96985.1 - 0.042 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 EMC96985.1 - 0.063 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Cupin HPP PF04982.13 EMC96986.1 - 9.1e-39 132.4 10.2 9.1e-39 132.4 10.2 1.9 2 0 0 2 2 2 1 HPP family DUF1375 PF07119.12 EMC96986.1 - 0.14 12.5 2.0 0.25 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) ATP11 PF06644.11 EMC96986.1 - 0.58 9.9 3.1 0.84 9.4 3.1 1.1 1 0 0 1 1 1 0 ATP11 protein Metal_resist PF13801.6 EMC96986.1 - 3.3 7.9 5.8 21 5.3 1.3 2.3 2 0 0 2 2 2 0 Heavy-metal resistance ORC2 PF04084.14 EMC96987.1 - 3.8e-118 394.2 0.0 4.5e-118 394.0 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF2848 PF11010.8 EMC96988.1 - 0.19 11.3 0.0 0.2 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) Adenylsucc_synt PF00709.21 EMC96989.1 - 1.4e-168 561.2 0.0 1.6e-168 561.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Pho88 PF10032.9 EMC96990.1 - 1.6e-83 278.4 0.1 1.8e-83 278.3 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) MBOAT PF03062.19 EMC96991.1 - 2.2e-49 168.7 4.5 4.3e-49 167.7 4.5 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Bac_rhamnosid6H PF17389.2 EMC96992.1 - 4.9e-18 65.5 3.9 8.7e-18 64.7 2.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EMC96992.1 - 7.9e-10 38.4 0.1 2.3e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Cyclin_C_2 PF16899.5 EMC96993.1 - 2.7e-32 111.3 0.5 1.4e-29 102.5 0.0 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EMC96993.1 - 3.6e-07 30.0 0.1 6.2e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain F-box PF00646.33 EMC96994.1 - 0.00014 21.6 0.7 0.00036 20.3 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EMC96994.1 - 0.0094 15.8 0.4 0.046 13.6 0.1 2.4 2 0 0 2 2 2 1 F-box-like 2-Hacid_dh_C PF02826.19 EMC96995.1 - 6.4e-51 172.2 0.0 1e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMC96995.1 - 2.1e-35 121.3 0.0 2.8e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMC96995.1 - 0.0003 21.0 0.5 0.00094 19.4 0.2 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EMC96995.1 - 0.0012 18.9 0.3 0.0037 17.3 0.1 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 EMC96995.1 - 0.0027 17.4 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 EMC96995.1 - 0.0053 16.3 0.3 0.061 12.9 0.1 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EMC96995.1 - 0.071 13.6 0.0 0.22 12.0 0.0 1.9 1 1 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 EMC96995.1 - 0.21 10.8 1.8 1 8.6 0.6 2.4 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 4HBT PF03061.22 EMC96997.1 - 3.2e-05 24.2 0.0 0.00013 22.3 0.0 2.0 1 1 0 1 1 1 1 Thioesterase superfamily Exo_endo_phos PF03372.23 EMC96998.1 - 6.1e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 EMC96998.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain DCP1 PF06058.13 EMC96999.1 - 2.6e-33 114.4 0.0 3.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Rit1_C PF17184.4 EMC97001.1 - 6.3e-101 337.4 0.0 1.9e-100 335.8 0.0 1.6 2 0 0 2 2 2 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EMC97001.1 - 1.5e-29 102.5 0.0 3.5e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain Radical_SAM_C PF16199.5 EMC97002.1 - 2.9e-32 110.5 0.1 7e-32 109.3 0.1 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EMC97002.1 - 3.6e-18 66.5 0.0 9.8e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EMC97002.1 - 8.9e-09 35.6 0.2 1.9e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC97002.1 - 1.8e-05 24.7 0.0 4.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC97002.1 - 0.03 14.8 0.1 0.07 13.6 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NPR3 PF03666.13 EMC97006.1 - 0.086 11.6 4.3 0.098 11.4 4.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 His_biosynth PF00977.21 EMC97007.1 - 2.3e-30 105.8 0.0 2.9e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EMC97007.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.6 EMC97008.1 - 1.7e-18 67.2 1.5 2.2e-18 66.9 1.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) VGLL4 PF15245.6 EMC97008.1 - 0.018 15.1 0.1 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 STE PF02200.16 EMC97010.1 - 5e-56 187.8 0.1 7.6e-56 187.2 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EMC97010.1 - 1e-09 38.3 11.1 0.0001 22.6 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC97010.1 - 9.1e-08 32.2 2.8 9.1e-08 32.2 2.8 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC97010.1 - 5.2e-07 30.0 8.9 0.0048 17.6 0.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMC97010.1 - 0.00036 20.5 0.9 0.00036 20.5 0.9 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMC97010.1 - 0.0037 17.5 0.7 0.075 13.4 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC97010.1 - 0.13 12.7 2.3 0.4 11.1 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Striatin PF08232.12 EMC97011.1 - 4.3e-44 150.8 7.3 4.3e-44 150.8 7.3 1.7 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 EMC97011.1 - 8.8e-27 92.8 15.1 0.0002 22.1 0.3 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC97011.1 - 9.1e-06 25.9 0.0 1 9.7 0.0 4.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-binding PF00249.31 EMC97012.1 - 0.045 14.0 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC97012.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain ADH_zinc_N PF00107.26 EMC97013.1 - 3e-12 46.6 0.0 4.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC97013.1 - 6.6e-06 27.2 0.0 8.2e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC97014.1 - 3.8e-20 71.8 2.0 5e-20 71.4 1.9 1.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cpn60_TCP1 PF00118.24 EMC97015.1 - 1.9e-87 294.0 12.2 7.7e-87 292.0 12.5 1.8 2 1 0 2 2 2 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 EMC97015.1 - 0.055 13.8 0.2 0.19 12.1 0.2 2.0 1 0 0 1 1 1 0 Transcriptional regulator UPRTase PF14681.6 EMC97017.1 - 7e-81 270.6 0.0 1.1e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EMC97017.1 - 0.0043 16.6 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RecQ5 PF06959.11 EMC97019.1 - 0.02 14.9 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) WAPL PF07814.13 EMC97020.1 - 3.7e-43 147.7 6.4 3.7e-43 147.7 6.4 1.9 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin DUF383 PF04063.14 EMC97020.1 - 0.00045 19.9 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF383) DUF4719 PF15843.5 EMC97020.1 - 3.8 7.6 6.1 0.24 11.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) DUF3405 PF11885.8 EMC97021.1 - 1.4e-227 756.4 0.1 1.8e-227 756.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Formyl_trans_N PF00551.19 EMC97023.1 - 1e-26 93.8 0.0 1.5e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Peptidase_C78 PF07910.13 EMC97024.1 - 3.5e-46 157.3 0.0 6.9e-46 156.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C78 zf_UBZ PF18439.1 EMC97024.1 - 0.022 14.4 0.2 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EMC97024.1 - 0.024 14.9 0.2 0.024 14.9 0.2 2.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 EMC97024.1 - 0.2 11.9 0.5 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RRN7 PF11781.8 EMC97026.1 - 0.21 11.3 0.7 0.21 11.3 0.7 1.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RFX_DNA_binding PF02257.15 EMC97029.1 - 3.9e-28 97.9 0.0 1.2e-27 96.4 0.0 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.19 EMC97030.1 - 1.5e-28 98.5 8.3 1.5e-28 98.5 8.3 1.7 1 1 1 2 2 2 2 TB2/DP1, HVA22 family Sec8_exocyst PF04048.14 EMC97031.1 - 6.4e-43 146.0 0.1 1.5e-42 144.9 0.1 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EMC97031.1 - 3.6e-08 33.0 0.1 7.5e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Exonuc_VII_L PF02601.15 EMC97031.1 - 0.57 9.7 3.1 0.53 9.8 0.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit TPR_2 PF07719.17 EMC97032.1 - 2e-22 77.4 22.3 0.0075 16.3 0.0 12.5 12 1 1 13 13 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 EMC97032.1 - 7.8e-22 76.1 8.5 0.029 14.2 0.0 11.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 EMC97032.1 - 1.4e-16 60.5 26.1 0.0016 18.7 0.2 10.4 9 3 2 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 EMC97032.1 - 6.5e-14 52.2 25.0 0.008 16.7 0.1 9.1 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EMC97032.1 - 8.7e-14 50.5 12.8 1 9.7 0.0 11.8 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMC97032.1 - 2.1e-11 43.4 8.0 5.4 7.6 0.1 10.4 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 EMC97032.1 - 3e-11 43.2 23.4 0.0055 17.3 0.1 11.6 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMC97032.1 - 3.6e-10 39.2 21.1 0.15 12.2 0.0 9.3 10 1 1 11 11 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EMC97032.1 - 2.3e-09 36.8 7.5 0.33 10.7 0.0 9.4 9 1 0 9 9 9 3 TPR repeat TPR_14 PF13428.6 EMC97032.1 - 1.8e-08 34.5 32.7 0.003 18.2 0.3 11.9 12 2 2 14 14 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 EMC97032.1 - 7.3e-07 29.7 23.9 0.0024 18.5 0.9 9.4 8 3 4 12 12 12 3 Tetratricopeptide repeat TPR_10 PF13374.6 EMC97032.1 - 1.1e-06 28.3 26.0 0.0047 16.8 0.0 8.3 8 0 0 8 8 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMC97032.1 - 0.00021 21.3 1.1 32 4.7 0.0 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 EMC97032.1 - 0.096 13.4 11.0 17 6.4 0.0 6.2 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1980 PF09323.10 EMC97033.1 - 0.082 12.8 0.1 0.14 12.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Pox_A14 PF05767.12 EMC97033.1 - 0.36 11.0 2.5 0.85 9.8 0.1 2.4 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF1772 PF08592.11 EMC97033.1 - 0.62 10.4 8.4 5.3 7.3 8.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) TSP_1 PF00090.19 EMC97034.1 - 0.025 14.8 0.1 0.068 13.4 0.1 1.7 1 1 0 1 1 1 0 Thrombospondin type 1 domain MIT PF04212.18 EMC97035.1 - 2.4e-32 110.8 8.7 1.5e-17 63.4 2.8 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EMC97035.1 - 0.00046 20.1 1.9 1.1 9.5 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EMC97035.1 - 0.0006 19.7 4.0 0.35 11.0 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.7 EMC97035.1 - 0.003 17.8 0.0 0.24 11.7 0.0 2.4 2 0 0 2 2 2 1 Tetratrico peptide repeat TPR_12 PF13424.6 EMC97035.1 - 0.0033 17.7 0.8 1.2 9.5 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat USP8_dimer PF08969.11 EMC97035.1 - 0.055 13.7 0.7 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 USP8 dimerisation domain Rootletin PF15035.6 EMC97035.1 - 0.074 13.1 3.3 0.31 11.0 3.3 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TPR_1 PF00515.28 EMC97035.1 - 0.13 12.1 3.7 1.2 9.1 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMC97035.1 - 0.13 12.0 3.2 2.4 7.9 0.4 2.7 2 0 0 2 2 2 0 TPR repeat TPR_3 PF07720.12 EMC97035.1 - 0.25 11.4 2.2 5.9 7.0 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMC97035.1 - 0.28 11.5 4.4 8.2 6.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat COX7C PF02935.16 EMC97036.1 - 3.1e-23 81.8 5.5 3.7e-23 81.6 5.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc CoA_binding PF02629.19 EMC97037.1 - 1.1e-28 99.8 2.4 1.6e-28 99.2 0.5 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EMC97037.1 - 9e-23 80.8 0.1 1.4e-22 80.2 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EMC97037.1 - 2.3e-08 33.9 0.0 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EMC97037.1 - 2.2e-05 24.9 0.0 4.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 EMC97037.1 - 0.018 15.9 0.0 0.038 14.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short_C2 PF13561.6 EMC97038.1 - 1.3e-63 214.7 4.1 1.4e-63 214.5 4.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC97038.1 - 2.3e-49 167.5 2.4 2.7e-49 167.3 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC97038.1 - 1.4e-16 61.0 2.6 2e-16 60.4 2.3 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMC97038.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EMC97038.1 - 0.00062 19.3 0.0 0.00098 18.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EMC97038.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 EMC97038.1 - 0.0018 18.4 0.3 0.0029 17.7 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 EMC97038.1 - 0.005 16.3 0.1 0.0089 15.5 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DNA_ligase_C PF17879.1 EMC97038.1 - 0.0093 16.0 0.1 1.9 8.6 0.0 2.7 3 0 0 3 3 3 1 DNA ligase C-terminal domain DFP PF04127.15 EMC97038.1 - 0.01 15.7 0.2 0.017 15.0 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.18 EMC97038.1 - 0.011 16.0 0.2 0.027 14.8 0.1 1.6 2 0 0 2 2 2 0 TrkA-N domain YjeF_N PF03853.15 EMC97038.1 - 0.015 15.1 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus ADH_zinc_N PF00107.26 EMC97038.1 - 0.025 14.6 1.9 0.08 12.9 0.8 2.4 1 1 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EMC97038.1 - 0.028 15.1 0.1 0.086 13.6 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase domain 3Beta_HSD PF01073.19 EMC97038.1 - 0.031 13.3 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 EMC97038.1 - 0.047 13.0 0.1 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EMC97038.1 - 0.057 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EMC97038.1 - 0.066 12.3 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain bMG1 PF17970.1 EMC97038.1 - 0.11 12.5 0.7 7.7 6.6 0.3 2.3 1 1 1 2 2 2 0 Bacterial Alpha-2-macroglobulin MG1 domain UDPG_MGDP_dh_N PF03721.14 EMC97038.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AAA PF00004.29 EMC97039.1 - 3.7e-17 63.0 0.0 6.4e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EMC97039.1 - 1.7e-15 57.2 0.0 6e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EMC97039.1 - 7.9e-13 48.5 1.0 1.3e-12 47.8 0.0 1.9 2 1 0 2 2 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EMC97039.1 - 1.8e-09 37.8 0.0 3.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EMC97039.1 - 3.9e-07 30.3 0.0 1.5e-06 28.4 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 EMC97039.1 - 4.2e-07 29.9 0.0 8.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EMC97039.1 - 2e-06 27.8 0.3 7.9e-06 25.9 0.1 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC97039.1 - 2.5e-06 28.0 0.0 1.8e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 EMC97039.1 - 2.8e-06 27.3 1.0 0.00031 20.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EMC97039.1 - 4.7e-06 26.9 0.0 1.5e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EMC97039.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit ResIII PF04851.15 EMC97039.1 - 4.8e-05 23.4 0.0 0.053 13.5 0.0 2.2 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_24 PF13479.6 EMC97039.1 - 5.3e-05 23.0 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EMC97039.1 - 8.2e-05 21.9 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 EMC97039.1 - 0.00011 22.0 0.1 0.00048 20.0 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EMC97039.1 - 0.0002 21.7 0.1 0.00061 20.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMC97039.1 - 0.00022 21.0 0.0 0.00066 19.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 EMC97039.1 - 0.00059 19.2 0.0 0.00094 18.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EMC97039.1 - 0.00064 19.8 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EMC97039.1 - 0.0014 18.1 0.3 0.38 10.2 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.26 EMC97039.1 - 0.0017 18.1 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DEAD PF00270.29 EMC97039.1 - 0.0035 17.1 0.3 0.021 14.6 0.2 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase TK PF00265.18 EMC97039.1 - 0.0036 17.2 0.1 0.0095 15.8 0.1 1.6 1 1 1 2 2 2 1 Thymidine kinase AAA_28 PF13521.6 EMC97039.1 - 0.0036 17.6 0.0 0.008 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EMC97039.1 - 0.0061 16.0 0.1 0.041 13.3 0.1 2.1 1 1 0 1 1 1 1 Bacterial TniB protein AAA_18 PF13238.6 EMC97039.1 - 0.0089 16.6 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EMC97039.1 - 0.0096 15.5 0.1 0.064 12.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EMC97039.1 - 0.012 15.0 0.1 0.13 11.6 0.1 2.5 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EMC97039.1 - 0.021 14.5 0.1 0.43 10.3 0.1 2.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EMC97039.1 - 0.029 13.9 0.0 0.089 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EMC97039.1 - 0.033 14.6 0.0 0.074 13.4 0.0 1.6 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EMC97039.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 EMC97039.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sec1 PF00995.23 EMC97040.1 - 8.9e-133 444.5 0.0 1e-132 444.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family NAD_binding_8 PF13450.6 EMC97041.1 - 1.1e-07 32.0 0.3 2e-07 31.1 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMC97041.1 - 1.4e-07 31.2 0.0 5.2e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EMC97041.1 - 5.8e-05 22.6 3.0 6e-05 22.6 1.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMC97041.1 - 0.0001 21.5 2.3 0.00016 20.9 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMC97041.1 - 0.00016 20.6 0.6 0.00027 19.8 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EMC97041.1 - 0.00019 20.8 0.6 0.00052 19.3 0.5 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC97041.1 - 0.00042 19.6 0.6 0.0007 18.9 0.6 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EMC97041.1 - 0.0017 17.5 0.4 0.0056 15.8 0.4 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 EMC97041.1 - 0.0019 17.8 3.3 0.021 14.4 2.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMC97041.1 - 0.0093 15.3 0.1 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC97041.1 - 0.01 15.1 0.2 0.015 14.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EMC97041.1 - 0.013 14.5 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EMC97041.1 - 0.019 15.5 0.6 0.042 14.4 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMC97041.1 - 0.045 13.0 0.5 0.08 12.2 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain VirC1 PF07015.11 EMC97041.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein Trp_halogenase PF04820.14 EMC97041.1 - 0.19 10.5 0.8 0.28 10.0 0.8 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.16 EMC97042.1 - 3.5e-34 118.3 43.5 3.5e-34 118.3 43.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EMC97042.1 - 2e-05 23.1 3.3 2e-05 23.1 3.3 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 EMC97044.1 - 1.4e-36 126.2 0.0 2.1e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 BURP PF03181.15 EMC97046.1 - 0.0046 16.6 0.2 0.0054 16.3 0.2 1.2 1 0 0 1 1 1 1 BURP domain IKI3 PF04762.12 EMC97050.1 - 7.5e-276 917.8 0.0 5.9e-144 481.3 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 EMC97050.1 - 0.00016 21.9 0.9 1.9 8.8 0.0 5.6 3 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Se-cys_synth_N PF12390.8 EMC97050.1 - 0.099 12.9 0.1 2.2 8.6 0.0 2.8 2 0 0 2 2 2 0 Selenocysteine synthase N terminal PEPcase PF00311.17 EMC97050.1 - 1.6 6.7 10.1 1.1 7.2 3.4 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase HhH-GPD PF00730.25 EMC97051.1 - 2.3e-13 50.5 0.0 3.5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Hpr_kinase_C PF07475.12 EMC97051.1 - 0.2 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain UCR_14kD PF02271.16 EMC97052.1 - 1.9e-43 146.5 0.1 2.2e-43 146.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 EMC97053.1 - 2e-63 210.3 3.1 1.3e-22 79.5 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein LEM PF03020.15 EMC97054.1 - 0.0045 16.5 0.0 0.34 10.5 0.0 2.7 2 0 0 2 2 2 2 LEM domain SAP PF02037.27 EMC97054.1 - 0.019 14.7 0.2 0.26 11.1 0.0 2.7 3 0 0 3 3 3 0 SAP domain Nucleoporin_C PF03177.14 EMC97055.1 - 1.3e-116 390.7 13.3 1.7e-116 390.4 13.3 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EMC97055.1 - 2e-40 138.9 0.0 2.6e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like RGS PF00615.19 EMC97058.1 - 1.1e-30 106.3 0.0 2.5e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 EMC97058.1 - 4.1e-24 84.4 0.0 8.5e-20 70.6 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) B_solenoid_ydck PF18836.1 EMC97058.1 - 1 9.4 4.4 0.87 9.5 0.5 2.3 2 0 0 2 2 2 0 Beta solenoid repeat from YDCK Pkinase PF00069.25 EMC97059.1 - 4e-55 187.0 0.0 5.9e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97059.1 - 8e-22 77.8 0.0 1.4e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC97059.1 - 5.2e-06 26.0 0.0 1.1e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMC97059.1 - 0.14 11.4 0.0 0.47 9.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EMC97060.1 - 5.6e-27 94.7 0.0 8.1e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97060.1 - 1.8e-14 53.7 0.0 2.5e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMC97060.1 - 3.1e-07 29.5 0.1 3.1e-07 29.5 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase Peptidase_M44 PF03410.13 EMC97060.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox TFIIA PF03153.13 EMC97060.1 - 6 6.8 15.2 9.5 6.1 15.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3484 PF11983.8 EMC97060.1 - 7 7.8 10.9 2.3 9.4 5.7 2.6 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch CIAPIN1 PF05093.13 EMC97061.1 - 6.4e-40 135.7 3.6 1.1e-39 134.9 3.6 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EMC97061.1 - 3.3e-38 130.9 0.0 5.1e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus TRI12 PF06609.13 EMC97063.1 - 1.5e-24 86.4 31.2 1.9e-24 86.1 31.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EMC97063.1 - 6.9e-16 58.1 66.2 7.6e-16 58.0 61.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_76 PF03663.14 EMC97064.1 - 4.1e-32 112.1 22.4 5.1e-32 111.8 22.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 FliS PF02561.14 EMC97064.1 - 0.047 13.9 0.1 6.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein FliS Glug PF07581.12 EMC97064.1 - 0.81 10.2 3.3 2.8 8.6 0.1 2.7 2 0 0 2 2 2 0 The GLUG motif NAD_binding_10 PF13460.6 EMC97065.1 - 0.00019 21.4 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC97065.1 - 0.005 16.3 0.0 0.0093 15.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 EMC97066.1 - 3.8e-16 59.4 0.4 5e-16 59.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC97066.1 - 9.6e-13 48.0 0.4 2.7e-12 46.5 0.5 1.7 1 1 1 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 EMC97066.1 - 2.8e-05 23.7 0.2 6.2e-05 22.6 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC97066.1 - 0.00034 20.5 0.1 0.00056 19.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC97066.1 - 0.0065 16.1 0.2 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EMC97066.1 - 0.007 16.3 0.2 0.026 14.4 0.2 2.0 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EMC97066.1 - 0.0082 15.3 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 EMC97066.1 - 0.027 14.3 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 EMC97066.1 - 0.035 13.9 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 EMC97066.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PPR_3 PF13812.6 EMC97066.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Methyltr_RsmB-F PF01189.17 EMC97068.1 - 4.9e-76 254.8 0.0 7.5e-76 254.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EMC97068.1 - 1.6e-07 31.7 0.0 4.1e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EMC97068.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Abhydrolase_3 PF07859.13 EMC97069.1 - 1.4e-41 142.7 0.0 1.9e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC97069.1 - 0.0015 18.0 0.0 0.0039 16.7 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EMC97069.1 - 0.0021 17.0 0.0 0.0029 16.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EMC97069.1 - 0.008 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF2920 PF11144.8 EMC97069.1 - 0.19 10.8 0.0 11 5.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) STE3 PF02076.15 EMC97070.1 - 1.1e-81 274.2 22.0 1.4e-81 273.9 22.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor UDPG_MGDP_dh_N PF03721.14 EMC97071.1 - 6.3e-48 162.8 0.0 8.6e-47 159.1 0.0 2.1 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EMC97071.1 - 5.1e-32 109.9 0.0 9.1e-32 109.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EMC97071.1 - 1.9e-24 86.1 0.0 2.9e-20 72.6 0.0 3.1 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 EMC97071.1 - 0.00018 21.8 0.1 0.00035 20.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EMC97071.1 - 0.033 13.8 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EMC97071.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.20 EMC97072.1 - 3.4e-35 121.1 0.0 4.6e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMC97072.1 - 2.2e-29 102.6 0.0 3.8e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMC97072.1 - 1.2e-10 41.7 0.0 2.5e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EMC97072.1 - 1.9e-08 34.6 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EMC97072.1 - 4.2e-07 30.5 0.0 9.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF3090 PF11290.8 EMC97072.1 - 0.035 13.9 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) DUF2309 PF10070.9 EMC97072.1 - 0.077 11.3 0.0 0.085 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) DUF4349 PF14257.6 EMC97072.1 - 0.17 11.3 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Pkinase PF00069.25 EMC97075.1 - 3.7e-66 223.2 0.5 3.4e-65 220.0 0.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97075.1 - 1.1e-51 175.6 0.5 1.7e-51 175.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EMC97075.1 - 2.3e-20 72.7 0.0 6.1e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 EMC97075.1 - 3.9e-10 40.2 0.3 1.2e-09 38.7 0.3 1.9 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 EMC97075.1 - 2.2e-05 23.4 2.0 3.2e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EMC97075.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 EMC97075.1 - 0.051 14.0 0.6 0.31 11.5 0.6 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 EMC97075.1 - 0.12 12.8 3.7 10 6.5 0.3 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain APH PF01636.23 EMC97075.1 - 0.23 11.4 3.6 1.3 8.8 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family adh_short PF00106.25 EMC97077.1 - 1.2e-27 96.7 0.0 1.9e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC97077.1 - 7.7e-19 68.2 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC97077.1 - 0.0036 17.2 2.3 0.24 11.3 2.3 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC97077.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 EMC97078.1 - 1.2e-09 37.4 0.0 3.2e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 DUF2838 PF10998.8 EMC97079.1 - 0.18 12.0 7.9 0.24 11.7 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) LapA_dom PF06305.11 EMC97079.1 - 0.21 11.4 2.9 0.7 9.7 2.2 2.3 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AMPKBI PF04739.15 EMC97080.1 - 4.3e-25 87.8 0.5 2.1e-24 85.6 0.5 2.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 EMC97080.1 - 6.1e-25 87.3 0.0 1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Fungal_trans_2 PF11951.8 EMC97082.1 - 2.7e-05 23.2 0.1 3.9e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAN_3 PF08277.12 EMC97084.1 - 1.4e-07 31.2 9.9 0.0021 17.8 0.9 2.8 2 0 0 2 2 2 2 PAN-like domain zinc_ribbon_9 PF14369.6 EMC97084.1 - 0.19 12.0 14.3 0.39 11.0 2.0 4.1 3 0 0 3 3 3 0 zinc-ribbon PAN_4 PF14295.6 EMC97084.1 - 1.8 8.6 22.4 0.099 12.6 1.0 4.4 4 0 0 4 4 4 0 PAN domain ABC_membrane PF00664.23 EMC97085.1 - 6.4e-107 357.3 39.1 1e-55 189.4 15.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EMC97085.1 - 4.7e-67 224.7 0.0 1.1e-32 113.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMC97085.1 - 8.7e-15 54.7 0.0 4.5e-05 23.0 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EMC97085.1 - 7.3e-08 33.0 0.5 0.0065 16.9 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMC97085.1 - 7.7e-08 32.4 0.0 0.083 12.8 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase ABC_ATPase PF09818.9 EMC97085.1 - 3e-06 26.3 0.3 0.03 13.1 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EMC97085.1 - 3.5e-05 23.4 6.5 0.006 16.3 0.2 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EMC97085.1 - 0.00012 22.4 2.7 0.11 12.8 0.1 3.6 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMC97085.1 - 0.0002 21.2 2.3 0.36 10.5 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 EMC97085.1 - 0.00038 20.9 2.6 2.1 8.8 0.1 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EMC97085.1 - 0.0013 18.3 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region G-alpha PF00503.20 EMC97085.1 - 0.0013 17.9 0.0 0.61 9.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 EMC97085.1 - 0.0016 18.6 0.2 0.41 10.7 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 EMC97085.1 - 0.0017 18.0 0.0 1.1 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMC97085.1 - 0.003 17.8 0.4 0.36 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EMC97085.1 - 0.0032 17.2 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EMC97085.1 - 0.0062 15.8 0.5 3.8 6.7 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin SbcCD_C PF13558.6 EMC97085.1 - 0.008 16.4 3.4 3.9 7.8 0.5 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EMC97085.1 - 0.012 15.4 3.1 9.6 5.9 0.4 3.9 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 EMC97085.1 - 0.025 14.6 0.5 13 5.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EMC97085.1 - 0.026 15.1 0.6 15 6.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EMC97085.1 - 0.03 14.5 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EMC97085.1 - 0.036 13.8 0.1 0.92 9.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 EMC97085.1 - 0.04 14.4 0.1 3 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EMC97085.1 - 0.041 13.6 0.1 3 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EMC97085.1 - 0.042 13.5 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 EMC97085.1 - 0.045 13.7 0.9 0.67 9.8 0.1 2.6 3 0 0 3 3 2 0 Adenylylsulphate kinase ATP-synt_ab PF00006.25 EMC97085.1 - 0.048 13.3 0.0 13 5.4 0.0 3.3 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 EMC97085.1 - 0.064 12.4 0.0 4 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 EMC97085.1 - 0.069 13.1 0.1 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 EMC97085.1 - 0.16 12.4 0.4 13 6.2 0.0 3.2 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.23 EMC97085.1 - 1.7 8.7 3.5 20 5.3 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF3169 PF11368.8 EMC97087.1 - 0.1 12.1 2.0 0.18 11.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Methyltransf_31 PF13847.6 EMC97088.1 - 1.8e-19 70.0 0.0 3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC97088.1 - 4.6e-18 65.7 0.0 1.1e-17 64.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC97088.1 - 6.3e-16 58.8 0.1 1.3e-15 57.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC97088.1 - 1.6e-14 54.5 0.2 4.4e-14 53.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC97088.1 - 4.6e-13 49.0 0.0 7.8e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EMC97088.1 - 4.7e-10 39.6 0.0 7.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMC97088.1 - 1.5e-09 37.9 0.1 4.9e-09 36.3 0.1 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EMC97088.1 - 5.1e-07 30.0 0.2 5.4e-06 26.6 0.2 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 EMC97088.1 - 1.3e-05 24.8 0.1 2.6e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EMC97088.1 - 0.00026 20.4 0.0 0.0018 17.6 0.0 2.2 3 1 0 3 3 3 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EMC97088.1 - 0.00036 19.6 0.0 0.00052 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GCD14 PF08704.10 EMC97088.1 - 0.0071 16.1 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit UPF0020 PF01170.18 EMC97088.1 - 0.0087 15.8 0.1 0.17 11.6 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 EMC97088.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 EMC97088.1 - 0.013 15.0 0.3 0.021 14.2 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 EMC97088.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltr_RsmB-F PF01189.17 EMC97088.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 EMC97088.1 - 0.016 15.1 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EMC97088.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.11 EMC97088.1 - 0.058 12.4 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase ADH_zinc_N PF00107.26 EMC97088.1 - 0.07 13.1 0.2 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase CheR PF01739.18 EMC97088.1 - 0.071 12.6 0.0 0.25 10.8 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DREV PF05219.12 EMC97088.1 - 0.081 12.0 0.0 0.18 10.9 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase DUF410 PF04190.13 EMC97089.1 - 1.3e-91 307.0 0.0 2e-91 306.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Fungal_trans PF04082.18 EMC97090.1 - 4.1e-08 32.6 1.7 1.8e-07 30.5 1.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC97090.1 - 8.2e-08 32.3 5.2 1.4e-07 31.5 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAF1 PF04857.20 EMC97092.1 - 1.5e-17 63.8 0.0 4.4e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 CAF1 family ribonuclease NDUF_B12 PF08122.12 EMC97094.1 - 2.3e-22 78.8 1.2 2.3e-22 78.8 1.2 1.5 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B12 subunit family KGG PF10685.9 EMC97095.1 - 0.022 15.0 16.2 0.077 13.3 2.6 3.1 3 0 0 3 3 3 0 Stress-induced bacterial acidophilic repeat motif Aminotran_1_2 PF00155.21 EMC97096.1 - 5.2e-83 279.2 0.0 6.5e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMC97096.1 - 0.00013 20.6 0.0 0.00024 19.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMC97096.1 - 0.0003 19.9 0.0 0.00069 18.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EMC97096.1 - 0.0015 17.9 0.2 0.0024 17.2 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family THOC2_N PF16134.5 EMC97097.1 - 1.6e-206 687.8 0.0 2.9e-206 686.9 0.0 1.4 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EMC97097.1 - 6.9e-85 284.9 0.1 1.2e-84 284.1 0.1 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EMC97097.1 - 3.2e-29 100.8 0.1 1.3e-28 98.9 0.1 2.1 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Thioredoxin PF00085.20 EMC97098.1 - 2.9e-06 27.2 0.2 8.8e-06 25.6 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EMC97098.1 - 0.013 15.9 0.1 0.022 15.2 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DnaJ_C PF01556.18 EMC97099.1 - 2.8e-38 131.3 1.6 3.7e-38 130.9 1.6 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMC97099.1 - 1.1e-24 86.3 2.3 2.3e-24 85.3 2.1 1.6 2 0 0 2 2 2 1 DnaJ domain RAI1 PF08652.11 EMC97100.1 - 3.4e-21 75.2 0.0 6.6e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease adh_short PF00106.25 EMC97101.1 - 4.2e-23 81.8 0.0 1.3e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC97101.1 - 3.9e-15 56.0 0.0 3.6e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC97101.1 - 0.00012 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Toxin_38 PF14866.6 EMC97102.1 - 0.022 15.0 3.5 0.059 13.7 3.5 1.7 1 0 0 1 1 1 0 Potassium channel toxin LTV PF04180.14 EMC97103.1 - 2.2e-115 386.5 7.3 2.5e-115 386.3 7.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 EMC97104.1 - 2.5e-17 63.0 0.1 4.3e-15 55.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMC97104.1 - 5.2e-07 29.3 0.3 1.3e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMC97104.1 - 2.2e-06 27.7 0.1 0.0032 17.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EMC97104.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 EMC97104.1 - 0.012 15.7 2.9 0.12 12.4 0.0 2.9 3 0 0 3 3 3 0 Dynamin family CDC45 PF02724.14 EMC97104.1 - 0.86 7.8 7.5 1.4 7.1 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EMC97104.1 - 2.3 6.7 6.0 3.1 6.2 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 EMC97104.1 - 4.2 6.4 16.5 7 5.7 16.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zinc_ribbon_6 PF14599.6 EMC97106.1 - 2.3e-18 66.0 1.2 6.1e-15 55.0 0.0 5.2 4 1 0 5 5 5 2 Zinc-ribbon zf-CHY PF05495.12 EMC97106.1 - 1.9e-16 60.3 24.0 1.9e-16 60.3 24.0 3.9 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.6 EMC97106.1 - 2.3e-08 34.2 2.7 2.3e-08 34.2 2.7 4.9 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMC97106.1 - 0.00014 21.6 5.1 0.00014 21.6 5.1 5.1 6 2 1 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC97106.1 - 0.0062 16.5 11.6 0.0062 16.5 11.6 5.9 4 4 0 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMC97106.1 - 0.0094 16.0 3.1 0.0094 16.0 3.1 3.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EMC97106.1 - 0.026 14.2 0.8 0.026 14.2 0.8 3.5 4 0 0 4 4 4 0 RING-like zinc finger Acyl_transf_1 PF00698.21 EMC97108.1 - 2.6e-21 76.5 0.0 1e-15 58.0 0.0 2.1 1 1 0 2 2 2 2 Acyl transferase domain ROS_MUCR PF05443.11 EMC97108.1 - 0.017 15.2 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein ELFV_dehydrog PF00208.21 EMC97109.1 - 1.7e-86 289.9 2.7 2.1e-86 289.6 2.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EMC97109.1 - 1.9e-51 173.4 0.0 3.5e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 EMC97109.1 - 0.0074 16.7 0.3 0.031 14.7 0.1 2.1 3 0 0 3 3 3 1 Putative NAD(P)-binding DUF5610 PF18433.1 EMC97110.1 - 0.087 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) UbiA PF01040.18 EMC97111.1 - 2.1e-41 141.9 23.7 2.7e-41 141.5 23.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4337 PF14235.6 EMC97111.1 - 0.0075 16.4 0.9 0.015 15.4 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) PNGaseA PF12222.8 EMC97115.1 - 6e-157 522.9 4.5 8.4e-157 522.5 4.5 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A JmjC PF02373.22 EMC97117.1 - 1.6e-09 38.1 1.0 1.3e-08 35.3 1.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EMC97117.1 - 1.7e-05 24.4 0.1 0.0038 16.9 0.0 2.7 2 0 0 2 2 2 2 Cupin domain zf-4CXXC_R1 PF10497.9 EMC97117.1 - 4.2e-05 23.7 8.4 4.2e-05 23.7 8.4 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_5 PF14634.6 EMC97119.1 - 0.00012 21.9 3.7 0.00049 20.0 3.8 1.9 1 1 1 2 2 2 1 zinc-RING finger domain Dynactin_p22 PF07426.11 EMC97119.1 - 0.0031 17.4 0.0 0.0043 16.9 0.0 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 FTA4 PF13093.6 EMC97119.1 - 0.0057 16.6 0.0 0.0061 16.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TMF_TATA_bd PF12325.8 EMC97119.1 - 0.034 14.4 2.4 0.049 13.9 2.4 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fer4_13 PF13370.6 EMC97119.1 - 0.039 14.5 2.1 1.3 9.7 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I zf_C2H2_10 PF18414.1 EMC97119.1 - 0.13 11.8 1.5 3.1 7.4 0.0 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger Endonuc_Holl PF10107.9 EMC97119.1 - 0.43 10.4 4.1 0.58 10.0 4.1 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase zf-RING_2 PF13639.6 EMC97119.1 - 8.8 6.7 8.3 1e+02 3.4 5.6 3.0 2 1 0 2 2 2 0 Ring finger domain adh_short_C2 PF13561.6 EMC97121.1 - 3.2e-45 154.5 0.5 3.7e-41 141.2 0.3 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC97121.1 - 1.4e-44 151.9 0.4 1.8e-44 151.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC97121.1 - 4.5e-17 62.5 0.2 6.8e-17 61.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC97121.1 - 7.2e-07 28.9 0.1 1.8e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Meth_synt_2 PF01717.18 EMC97123.1 - 9.2e-150 498.4 0.0 2.4e-145 483.8 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EMC97123.1 - 5.3e-121 403.9 0.0 3.1e-115 385.0 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EMC97123.1 - 0.00016 21.0 0.0 0.037 13.2 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 EMC97123.1 - 0.22 11.3 3.4 0.11 12.2 0.3 2.2 2 0 0 2 2 2 0 Short C-terminal domain HECT PF00632.25 EMC97125.1 - 6.4e-93 311.6 0.0 8.7e-93 311.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EMC97125.1 - 1.4e-32 111.4 18.3 1.2e-11 44.5 1.4 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EMC97125.1 - 2.6e-18 66.2 0.1 6.2e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 C2 domain Septin PF00735.18 EMC97126.1 - 7.8e-112 373.1 0.4 9.4e-112 372.9 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EMC97126.1 - 6e-08 32.8 0.0 1.3e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMC97126.1 - 2.4e-05 24.0 0.6 0.11 12.0 0.1 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EMC97126.1 - 3.3e-05 23.3 0.0 6.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EMC97126.1 - 4.2e-05 23.5 0.5 0.0004 20.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EMC97126.1 - 0.0007 19.7 0.4 0.82 9.7 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_7 PF12775.7 EMC97126.1 - 0.0072 15.9 0.1 0.052 13.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EMC97126.1 - 0.0073 16.7 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EMC97126.1 - 0.0078 15.4 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EMC97126.1 - 0.016 15.5 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EMC97126.1 - 0.025 15.1 1.1 0.043 14.3 1.0 1.8 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 EMC97126.1 - 0.031 13.6 0.1 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region T2SSE PF00437.20 EMC97126.1 - 0.06 12.4 0.0 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EMC97126.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 EMC97126.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EMC97126.1 - 0.086 12.0 0.3 0.74 8.9 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.6 EMC97126.1 - 0.097 13.2 0.2 0.19 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 EMC97126.1 - 0.13 12.1 0.3 0.95 9.4 0.0 2.1 2 0 0 2 2 2 0 Microtubule binding AAA_29 PF13555.6 EMC97126.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.23 EMC97127.1 - 1.6e-13 50.7 7.9 1.7e-13 50.6 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 EMC97127.1 - 0.01 15.2 1.4 0.015 14.7 1.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain WD40 PF00400.32 EMC97128.1 - 5.2e-20 71.4 5.5 9.5e-07 29.4 0.5 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC97128.1 - 1.7e-12 47.5 0.6 0.035 14.4 0.7 4.7 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMC97128.1 - 0.0003 20.7 0.2 0.024 14.5 0.0 3.3 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EMC97128.1 - 0.018 14.4 0.0 3.2 7.0 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 EMC97128.1 - 0.15 10.5 0.1 3.1 6.2 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain tRNA-synt_1g PF09334.11 EMC97130.1 - 2.1e-153 510.7 0.0 2.7e-153 510.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EMC97130.1 - 2.8e-09 35.8 0.6 2.3e-05 22.9 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) TMEM119 PF15724.5 EMC97130.1 - 0.31 11.1 4.1 0.51 10.4 4.1 1.2 1 0 0 1 1 1 0 TMEM119 family Laminin_EGF PF00053.24 EMC97130.1 - 0.32 11.2 3.5 0.67 10.1 3.5 1.6 1 0 0 1 1 1 0 Laminin EGF domain Pns11_12 PF17464.2 EMC97130.1 - 0.45 10.2 3.9 0.76 9.4 3.9 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Yae1_N PF09811.9 EMC97131.1 - 1.5e-10 40.6 2.9 1.5e-10 40.6 2.9 1.5 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Rad52_Rad22 PF04098.15 EMC97132.1 - 1.7e-61 206.6 0.0 2.6e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Peptidase_S10 PF00450.22 EMC97133.1 - 7.8e-116 387.9 0.0 1.1e-115 387.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_gE PF02480.16 EMC97133.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ank_2 PF12796.7 EMC97134.1 - 1.5e-26 92.8 1.7 1.2e-11 45.0 0.0 3.8 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC97134.1 - 3e-20 72.3 7.2 1.2e-06 29.0 0.4 5.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC97134.1 - 1.7e-18 64.8 1.9 0.005 17.2 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EMC97134.1 - 3e-18 65.7 8.7 2.4e-05 24.5 1.4 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EMC97134.1 - 9.8e-17 60.6 9.8 0.0019 18.5 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat CorA PF01544.18 EMC97134.1 - 1.1e-10 41.4 0.6 3.1e-10 39.8 0.2 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 EMC97134.1 - 0.003 17.6 0.1 0.0069 16.4 0.1 1.6 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III PEP-utilisers_N PF05524.13 EMC97134.1 - 2 8.6 5.2 3.4 7.9 1.2 2.9 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal AbLIM_anchor PF16182.5 EMC97136.1 - 0.03 14.2 2.9 0.037 13.9 2.9 1.0 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM ADIP PF11559.8 EMC97136.1 - 0.093 12.8 7.2 0.14 12.3 7.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tho2 PF11262.8 EMC97136.1 - 0.15 11.3 4.6 0.2 10.8 4.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 MRPL52 PF18699.1 EMC97136.1 - 0.27 11.5 9.5 0.43 10.8 9.5 1.2 1 0 0 1 1 1 0 Mitoribosomal protein mL52 DUF1609 PF07753.11 EMC97136.1 - 0.44 10.0 7.3 0.56 9.7 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) DDRGK PF09756.9 EMC97136.1 - 1.2 8.7 14.7 1.4 8.5 14.7 1.1 1 0 0 1 1 1 0 DDRGK domain ABC_tran PF00005.27 EMC97137.1 - 1.6e-47 161.5 0.0 8.5e-23 81.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EMC97137.1 - 7.2e-23 80.4 2.8 7.2e-23 80.4 2.8 2.7 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EMC97137.1 - 6e-20 72.3 1.4 0.00019 21.3 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMC97137.1 - 9.2e-11 41.6 0.2 0.021 14.3 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EMC97137.1 - 4e-09 37.3 1.5 0.029 14.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EMC97137.1 - 2.5e-08 33.5 0.1 0.0039 16.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EMC97137.1 - 7.8e-08 32.4 0.2 0.017 14.8 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EMC97137.1 - 4.8e-07 29.8 0.4 0.0011 18.9 0.1 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 EMC97137.1 - 2.1e-06 28.2 0.0 0.029 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EMC97137.1 - 6e-06 26.8 0.1 0.027 15.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_27 PF13514.6 EMC97137.1 - 3.6e-05 23.5 0.0 0.035 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EMC97137.1 - 5.3e-05 23.5 0.0 0.06 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMC97137.1 - 7.8e-05 22.7 0.0 0.084 13.0 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 EMC97137.1 - 0.00034 20.6 0.2 0.72 9.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.22 EMC97137.1 - 0.00082 18.6 0.0 2.8 7.1 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain AAA PF00004.29 EMC97137.1 - 0.00086 19.7 0.0 0.94 9.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMC97137.1 - 0.00096 19.5 0.5 2.6 8.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_28 PF13521.6 EMC97137.1 - 0.0018 18.5 0.0 0.66 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EMC97137.1 - 0.002 18.3 0.1 2.1 8.6 0.1 2.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EMC97137.1 - 0.004 16.9 0.9 2.5 7.8 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.14 EMC97137.1 - 0.0046 16.9 0.1 2.8 7.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EMC97137.1 - 0.0067 16.6 0.1 2.6 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EMC97137.1 - 0.019 15.0 0.0 6.9 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 EMC97137.1 - 0.027 14.0 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 EMC97137.1 - 0.036 14.0 0.0 13 5.7 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain Ras PF00071.22 EMC97137.1 - 0.037 13.6 0.0 8.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Ras family ABC_ATPase PF09818.9 EMC97137.1 - 0.037 12.8 0.1 7.7 5.2 0.0 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF2813 PF11398.8 EMC97137.1 - 0.046 13.0 0.0 6.1 6.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) MCM PF00493.23 EMC97137.1 - 0.047 12.8 0.0 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_25 PF13481.6 EMC97137.1 - 0.063 12.8 0.2 1.8 8.1 0.0 3.0 3 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EMC97137.1 - 0.1 12.3 0.1 7.3 6.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EMC97137.1 - 0.12 12.1 0.5 3.7 7.3 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 EMC97137.1 - 0.17 11.7 1.8 21 5.0 0.0 2.9 3 1 0 4 4 4 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 EMC97137.1 - 0.28 11.2 2.2 49 3.9 0.0 3.5 3 1 0 3 3 3 0 Dynamin family Skp1 PF01466.19 EMC97138.1 - 3.8e-29 100.5 0.7 8.2e-29 99.5 0.7 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EMC97138.1 - 6.8e-22 77.4 0.4 1.6e-21 76.3 0.2 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Ank_2 PF12796.7 EMC97141.1 - 3.2e-60 200.7 10.0 9.8e-15 54.9 0.1 5.2 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC97141.1 - 3.2e-30 104.1 9.6 2.9e-06 27.7 0.0 8.4 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EMC97141.1 - 2.3e-29 100.5 9.2 9.5e-05 22.7 0.0 8.6 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EMC97141.1 - 1.5e-25 88.9 3.9 1.4e-05 25.2 0.0 7.9 1 1 7 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC97141.1 - 1.8e-19 67.8 5.5 0.11 13.1 0.0 8.8 8 0 0 8 8 8 4 Ankyrin repeat NACHT PF05729.12 EMC97141.1 - 4.2e-11 43.0 0.0 9.3e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EMC97141.1 - 2.5e-05 24.5 0.1 0.00024 21.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMC97141.1 - 0.00085 19.7 0.0 0.0025 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SesA PF17107.5 EMC97141.1 - 0.0058 16.8 0.1 0.036 14.3 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 EMC97141.1 - 0.011 15.1 0.4 0.03 13.7 0.1 1.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins AAA PF00004.29 EMC97141.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CCDC-167 PF15188.6 EMC97141.1 - 0.018 15.3 1.2 7.6 7.0 0.6 3.4 4 0 0 4 4 3 0 Coiled-coil domain-containing protein 167 Hemolysin_N PF12563.8 EMC97141.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Hemolytic toxin N terminal NB-ARC PF00931.22 EMC97141.1 - 0.024 13.8 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EMC97141.1 - 0.045 14.1 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EMC97141.1 - 0.17 11.8 0.0 0.47 10.3 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Arg_repressor PF01316.21 EMC97141.1 - 0.29 10.9 6.5 25 4.7 0.0 5.4 7 0 0 7 7 7 0 Arginine repressor, DNA binding domain EAL PF00563.20 EMC97142.1 - 0.067 12.7 0.0 0.075 12.5 0.0 1.0 1 0 0 1 1 1 0 EAL domain MFS_2 PF13347.6 EMC97143.1 - 2.2e-11 43.0 13.4 1.1e-10 40.7 7.3 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 EMC97143.1 - 2e-08 33.6 18.7 2e-08 33.6 18.7 3.5 2 1 1 3 3 3 1 Major Facilitator Superfamily TMEM125 PF15109.6 EMC97143.1 - 0.037 14.4 0.4 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 TMEM125 protein family Na_H_Exchanger PF00999.21 EMC97144.1 - 8.1e-71 238.8 41.3 1e-70 238.5 41.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Kelch_6 PF13964.6 EMC97144.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 Kelch motif Myc_target_1 PF15179.6 EMC97144.1 - 1.6 8.6 4.0 2.2 8.1 0.3 2.6 2 0 0 2 2 2 0 Myc target protein 1 PepSY_TM PF03929.16 EMC97144.1 - 1.9 8.1 5.3 0.62 9.7 1.2 2.1 1 1 0 1 1 1 0 PepSY-associated TM region NmrA PF05368.13 EMC97145.1 - 2.5e-29 102.5 0.0 4.1e-29 101.8 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC97145.1 - 5.9e-09 36.1 0.0 8.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC97145.1 - 1.3e-05 24.8 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EMC97145.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 TrkA-N domain Cofilin_ADF PF00241.20 EMC97147.1 - 1.1e-39 135.0 0.1 1.3e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Lactamase_B_2 PF12706.7 EMC97149.1 - 2.2e-36 125.3 0.0 3.3e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMC97149.1 - 9.4e-13 48.4 0.0 1.6e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EMC97149.1 - 0.0034 17.4 1.7 0.39 10.7 1.8 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Myb_DNA-binding PF00249.31 EMC97151.1 - 1e-17 64.0 0.0 2.6e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EMC97151.1 - 1.8e-05 24.6 0.0 1.8e-05 24.6 0.0 3.4 4 0 0 4 4 4 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EMC97151.1 - 0.00047 20.4 0.0 0.81 10.0 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain DS PF01916.17 EMC97152.1 - 2.5e-134 447.0 0.0 2.9e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 EMC97152.1 - 0.12 12.0 0.2 0.19 11.4 0.2 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus MORN PF02493.20 EMC97153.1 - 2.3e-15 55.5 23.3 4.9e-06 26.1 0.5 4.8 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.6 EMC97153.1 - 3e-12 46.2 8.2 8.2e-12 44.8 8.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC97153.1 - 6.4e-06 25.9 7.3 1.3e-05 25.0 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UCH PF00443.29 EMC97153.1 - 8.5e-06 25.4 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.6 EMC97153.1 - 0.0055 17.0 9.6 0.013 15.8 9.6 1.7 1 0 0 1 1 1 1 Ring finger domain DUF2039 PF10217.9 EMC97153.1 - 0.062 13.7 4.3 0.17 12.2 4.3 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.6 EMC97153.1 - 0.2 11.6 9.4 0.48 10.4 9.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMC97153.1 - 0.45 10.6 4.5 0.62 10.1 1.6 2.5 1 1 1 2 2 2 0 RING-type zinc-finger Cut12 PF11500.8 EMC97154.1 - 1.4e-14 54.3 9.3 5.8e-14 52.3 9.3 1.9 1 1 0 1 1 1 1 Spindle pole body formation-associated protein ABC_tran_CTD PF16326.5 EMC97154.1 - 0.011 15.9 0.8 0.011 15.9 0.8 2.2 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF2570 PF10828.8 EMC97154.1 - 0.13 12.1 3.3 0.32 10.8 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) TSNAXIP1_N PF15739.5 EMC97154.1 - 2.8 8.3 9.8 0.52 10.7 4.3 2.2 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Tropomyosin PF00261.20 EMC97154.1 - 3.6 6.9 13.1 0.15 11.4 6.9 1.7 2 0 0 2 2 2 0 Tropomyosin Pkinase PF00069.25 EMC97155.1 - 4e-61 206.7 0.0 4.7e-35 121.2 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 EMC97155.1 - 2.4e-41 142.0 3.2 2.4e-41 142.0 3.2 2.5 2 1 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 EMC97155.1 - 6.3e-32 110.9 0.0 6.7e-16 58.3 0.0 4.1 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EMC97155.1 - 6.6e-16 58.6 0.1 3.7e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 EMC97155.1 - 1.8e-15 57.0 0.0 1.8e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 EMC97155.1 - 0.00069 19.6 0.0 0.00069 19.6 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EMC97155.1 - 0.0052 16.2 0.4 2.8 7.2 0.2 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EMC97155.1 - 0.026 14.1 0.0 3.3 7.3 0.0 3.4 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EMC97155.1 - 0.13 11.6 0.2 4.8 6.4 0.0 3.0 3 0 0 3 3 3 0 Kinase-like Pkinase PF00069.25 EMC97156.1 - 7.9e-62 209.0 0.0 1e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97156.1 - 2.2e-30 105.8 0.0 3.3e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EMC97156.1 - 6.3e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMC97156.1 - 6.6e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMC97156.1 - 0.00018 20.4 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EMC97156.1 - 0.00052 20.0 0.0 0.011 15.6 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMC97156.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 EMC97156.1 - 0.037 13.5 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Myosin_head PF00063.21 EMC97157.1 - 3.5e-256 851.7 0.0 3.5e-256 851.7 0.0 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 EMC97157.1 - 3.3e-26 91.6 2.6 3.3e-26 91.6 2.6 2.9 2 1 1 3 3 2 1 DIL domain IQ PF00612.27 EMC97157.1 - 5.7e-08 31.9 41.4 0.00032 20.2 0.4 7.0 7 0 0 7 7 6 3 IQ calmodulin-binding motif AAA_22 PF13401.6 EMC97157.1 - 4.7e-05 23.7 0.0 0.00021 21.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain Flagellin_N PF00669.20 EMC97157.1 - 0.0052 16.9 5.2 0.017 15.3 5.2 1.9 1 0 0 1 1 1 1 Bacterial flagellin N-terminal helical region Myosin_N PF02736.19 EMC97157.1 - 0.019 14.8 1.3 0.048 13.5 1.3 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain EzrA PF06160.12 EMC97157.1 - 0.066 11.4 16.8 0.2 9.8 0.9 2.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA AAA_16 PF13191.6 EMC97157.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain ATPase PF06745.13 EMC97157.1 - 0.16 11.3 3.3 12 5.2 0.0 2.6 2 0 0 2 2 2 0 KaiC Leu_zip PF15294.6 EMC97157.1 - 0.26 10.8 15.7 0.98 8.9 15.7 2.0 1 1 0 1 1 1 0 Leucine zipper Fez1 PF06818.15 EMC97157.1 - 0.31 11.5 30.0 0.15 12.5 11.3 3.0 2 1 1 3 3 3 0 Fez1 ABC_tran PF00005.27 EMC97157.1 - 0.36 11.4 2.4 5.1 7.6 0.0 3.0 2 1 0 2 2 2 0 ABC transporter ERM PF00769.19 EMC97157.1 - 0.43 10.3 27.4 1 9.1 27.4 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.6 EMC97157.1 - 0.5 9.7 27.7 0.47 9.8 10.5 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HSF_DNA-bind PF00447.17 EMC97157.1 - 0.54 10.9 2.6 1.6 9.4 0.7 2.7 2 0 0 2 2 2 0 HSF-type DNA-binding FPP PF05911.11 EMC97157.1 - 0.57 8.3 18.4 1.2 7.3 18.4 1.5 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DHR10 PF18595.1 EMC97157.1 - 0.68 10.0 30.6 2.1 8.4 5.5 3.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TolA_bind_tri PF16331.5 EMC97157.1 - 1.4 9.1 26.1 0.15 12.2 2.8 4.5 3 1 1 4 4 4 0 TolA binding protein trimerisation DegQ PF08181.11 EMC97157.1 - 3.3 7.9 5.3 0.7 10.0 0.3 2.5 2 0 0 2 2 1 0 DegQ (SacQ) family HIP1_clath_bdg PF16515.5 EMC97157.1 - 3.7 8.2 27.0 15 6.3 12.6 3.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3450 PF11932.8 EMC97157.1 - 5.8 6.1 26.3 3.1 7.0 13.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Uso1_p115_C PF04871.13 EMC97157.1 - 6.2 7.2 26.9 18 5.7 6.1 2.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region KASH_CCD PF14662.6 EMC97157.1 - 6.4 6.6 27.3 0.74 9.6 7.0 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Myb_DNA-bind_7 PF15963.5 EMC97158.1 - 2.6e-17 62.5 0.1 2.6e-17 62.5 0.1 2.8 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EMC97158.1 - 0.00028 21.1 0.0 0.00064 19.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMC97158.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RNAse_A_bac PF18431.1 EMC97158.1 - 0.011 16.7 1.9 0.037 15.0 1.9 1.9 1 0 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain BRE1 PF08647.11 EMC97159.1 - 1.4e-26 92.4 14.5 1.4e-26 92.4 14.5 7.7 5 3 2 7 7 7 2 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.6 EMC97159.1 - 1.7e-09 37.4 7.7 3.4e-09 36.4 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMC97159.1 - 8e-09 35.2 7.4 1.4e-08 34.5 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC97159.1 - 1.1e-07 31.5 9.0 2e-07 30.7 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC97159.1 - 3e-07 30.7 7.4 5.3e-07 29.9 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EMC97159.1 - 7e-06 25.8 5.7 1.4e-05 24.9 5.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EMC97159.1 - 2.3e-05 24.3 8.7 4e-05 23.5 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMC97159.1 - 3.2e-05 23.9 8.5 6.9e-05 22.8 8.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger GAS PF13851.6 EMC97159.1 - 0.00056 19.3 13.7 0.00056 19.3 13.7 6.3 3 1 3 6 6 6 2 Growth-arrest specific micro-tubule binding zf-C3HC4_4 PF15227.6 EMC97159.1 - 0.00065 19.8 6.9 0.0011 19.0 6.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EMC97159.1 - 0.0035 17.1 4.9 0.01 15.6 5.0 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EMC97159.1 - 0.012 15.9 5.5 0.028 14.7 5.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain NADH-G_4Fe-4S_3 PF10588.9 EMC97159.1 - 0.03 13.8 1.9 0.039 13.5 0.1 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C3HC4_5 PF17121.5 EMC97159.1 - 0.16 11.9 6.7 0.39 10.6 6.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EMC97159.1 - 0.19 11.8 7.2 0.65 10.1 7.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EMC97159.1 - 0.33 10.9 5.4 1.8 8.6 5.9 1.8 1 1 0 1 1 1 0 zinc-ribbons Rootletin PF15035.6 EMC97159.1 - 0.39 10.7 73.6 0.15 12.0 5.0 6.8 1 1 6 7 7 7 0 Ciliary rootlet component, centrosome cohesion zf-Nse PF11789.8 EMC97159.1 - 0.94 9.3 6.6 0.66 9.8 3.4 2.3 3 0 0 3 3 2 0 Zinc-finger of the MIZ type in Nse subunit Shugoshin_N PF07558.11 EMC97159.1 - 1.1 9.2 8.6 28 4.7 0.2 5.2 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region FYVE PF01363.21 EMC97159.1 - 1.5 9.0 8.3 13 6.0 8.6 2.2 1 1 0 1 1 1 0 FYVE zinc finger Rad50_zn_hook PF04423.14 EMC97159.1 - 3.6 7.5 7.7 11 5.9 0.0 4.7 4 0 0 4 4 4 0 Rad50 zinc hook motif MIG-14_Wnt-bd PF06664.12 EMC97160.1 - 0.0053 16.0 0.1 0.006 15.9 0.1 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Yip1 PF04893.17 EMC97160.1 - 0.013 15.3 0.4 0.015 15.0 0.4 1.1 1 0 0 1 1 1 0 Yip1 domain LtrA PF06772.11 EMC97160.1 - 0.02 14.1 0.4 0.024 13.9 0.4 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Cation_efflux PF01545.21 EMC97162.1 - 6.8e-22 78.2 11.3 8.6e-22 77.8 11.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EMC97162.1 - 1.2e-06 28.5 0.1 2.4e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PHBC_N PF12551.8 EMC97162.1 - 0.093 12.5 0.7 0.19 11.6 0.7 1.5 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal SLATT_1 PF18181.1 EMC97162.1 - 0.18 11.8 1.4 0.57 10.1 1.4 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Pkinase PF00069.25 EMC97163.1 - 1.5e-10 40.9 0.0 4.5e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97163.1 - 3.8e-08 32.9 0.0 2.5e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SMI1_KNR4 PF09346.10 EMC97165.1 - 1.4e-33 116.1 0.1 4e-33 114.6 0.1 1.8 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) F-box-like PF12937.7 EMC97166.1 - 0.00029 20.7 0.1 0.00089 19.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC97166.1 - 0.006 16.4 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EMC97166.1 - 0.13 12.1 0.1 0.44 10.5 0.1 1.9 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 EMC97167.1 - 0.014 15.3 2.2 0.082 12.8 0.8 2.3 2 0 0 2 2 2 0 F-box-like TF_Otx PF03529.13 EMC97168.1 - 0.14 12.5 3.1 0.22 11.9 2.5 1.6 1 1 1 2 2 2 0 Otx1 transcription factor MRP-S33 PF08293.11 EMC97170.1 - 2.5e-25 88.5 0.1 2.7e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.26 EMC97171.1 - 1.6e-16 60.8 0.0 3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EMC97171.1 - 4e-14 52.9 0.0 6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EMC97171.1 - 0.13 13.0 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Herpes_UL32 PF06070.11 EMC97171.1 - 6.8 4.3 6.0 9.6 3.8 6.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Pkinase PF00069.25 EMC97172.1 - 3.6e-58 197.0 0.1 5.7e-52 176.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97172.1 - 9.1e-37 126.7 0.1 1.9e-35 122.4 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC97172.1 - 1.9e-07 30.7 0.0 7.2e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EMC97172.1 - 0.00016 20.6 0.0 0.0005 18.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EMC97172.1 - 0.0014 18.6 0.0 0.0057 16.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Sybindin PF04099.12 EMC97173.1 - 4.2e-22 78.6 0.0 5.1e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family CSN8_PSD8_EIF3K PF10075.9 EMC97174.1 - 0.047 13.7 0.2 0.061 13.3 0.2 1.2 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family MBOAT_2 PF13813.6 EMC97175.1 - 1.9e-20 72.9 0.8 1.9e-20 72.9 0.8 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MMR_HSR1_Xtn PF16897.5 EMC97176.1 - 7.2e-35 119.2 1.4 8.1e-34 115.8 0.3 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EMC97176.1 - 5e-21 74.5 0.1 8.6e-21 73.8 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EMC97176.1 - 9.9e-20 70.7 0.0 2.4e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMC97176.1 - 1.1e-12 47.7 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EMC97176.1 - 0.00068 19.7 0.3 0.59 10.2 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EMC97176.1 - 0.062 12.3 0.2 0.16 10.9 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 EMC97176.1 - 0.094 11.8 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AIG1 PF04548.16 EMC97176.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 EMC97176.1 - 0.15 12.3 0.2 1.1 9.6 0.2 2.4 2 1 0 2 2 2 0 AAA domain AIRS_C PF02769.22 EMC97177.1 - 5.1e-27 94.9 0.0 8.7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EMC97177.1 - 8.9e-15 55.1 0.9 2.7e-14 53.6 0.9 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GHMP_kinases_N PF00288.26 EMC97177.1 - 9.1e-11 41.8 1.7 1.5e-10 41.1 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EMC97177.1 - 6.3e-05 23.3 0.0 0.00034 20.9 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal Sugar_tr PF00083.24 EMC97178.1 - 1.3e-112 377.0 22.8 1.5e-112 376.8 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC97178.1 - 4.5e-19 68.6 41.4 1.3e-12 47.3 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gcd10p PF04189.13 EMC97179.1 - 1.9e-110 368.7 0.0 2.2e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 Gcd10p family YqfD PF06898.11 EMC97179.1 - 0.056 12.3 0.2 0.085 11.7 0.2 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD tRNA-synt_1b PF00579.25 EMC97180.1 - 4.2e-76 256.1 0.0 5.2e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) EPL1 PF10513.9 EMC97181.1 - 8.9e-27 94.4 0.2 8.9e-27 94.4 0.2 1.8 2 1 0 2 2 2 1 Enhancer of polycomb-like DUF2508 PF10704.9 EMC97181.1 - 0.008 16.3 0.3 0.025 14.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2508) DUF5595 PF18077.1 EMC97181.1 - 1.3 9.1 4.8 2.9 8.1 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) DUF4363 PF14276.6 EMC97181.1 - 4.6 7.4 5.7 6.1 7.0 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) p450 PF00067.22 EMC97183.1 - 1.6e-44 152.4 0.0 2.1e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 EMC97185.1 - 4.1e-112 375.3 24.1 5e-112 375.0 24.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC97185.1 - 9.8e-21 74.1 50.1 2e-18 66.5 24.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC1 PF03109.16 EMC97186.1 - 8.5e-35 119.5 0.0 5.7e-34 116.8 0.0 2.3 2 0 0 2 2 2 1 ABC1 family Glyco_tranf_2_3 PF13641.6 EMC97187.1 - 1.2e-17 64.5 0.0 2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EMC97187.1 - 3.9e-17 62.8 4.0 3.9e-17 62.8 4.0 2.8 2 2 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMC97187.1 - 1.8e-15 57.2 0.0 2.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EMC97187.1 - 6.5e-09 35.5 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 EMC97187.1 - 4.2e-05 22.3 7.7 0.00015 20.4 5.7 2.2 1 1 0 2 2 2 1 Cellulose synthase Sugar_tr PF00083.24 EMC97188.1 - 4.4e-108 362.0 21.7 5.2e-108 361.8 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC97188.1 - 9e-20 70.9 22.8 9e-20 70.9 22.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1304 PF06993.12 EMC97188.1 - 0.069 13.1 10.3 1.4 9.0 2.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) DUF350 PF03994.14 EMC97188.1 - 6.3 7.0 9.8 0.78 9.9 0.1 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF350) Amidase PF01425.21 EMC97189.1 - 1.1e-104 350.9 0.0 3.6e-104 349.3 0.0 1.7 1 1 0 1 1 1 1 Amidase Mg_trans_NIPA PF05653.14 EMC97190.1 - 8.3e-62 208.9 4.5 6.1e-58 196.3 3.5 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EMC97190.1 - 3.4e-05 24.0 0.5 3.4e-05 24.0 0.5 4.0 3 1 0 3 3 3 1 EamA-like transporter family DUF4181 PF13789.6 EMC97190.1 - 1.8 8.9 6.3 2.4 8.4 5.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) Trp_oprn_chp PF09534.10 EMC97190.1 - 1.8 8.3 6.5 8.6 6.1 1.9 2.7 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) O-antigen_lig PF13425.6 EMC97190.1 - 2.2 7.0 10.0 1.3 7.7 6.5 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Acyl-CoA_dh_1 PF00441.24 EMC97191.1 - 1.4e-30 106.4 0.1 3e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMC97191.1 - 4.4e-19 68.5 0.0 8.1e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMC97191.1 - 7.7e-16 58.8 0.0 2.2e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMC97191.1 - 2e-11 44.3 0.2 3.3e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPA_C PF05181.12 EMC97193.1 - 2.5e-25 88.2 2.2 5.2e-25 87.2 2.2 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EMC97193.1 - 0.013 15.5 4.3 0.013 15.5 4.3 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zf-AD PF07776.15 EMC97193.1 - 0.032 14.5 0.9 0.085 13.1 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) ADD_DNMT3 PF17980.1 EMC97193.1 - 0.68 10.0 3.5 0.39 10.7 0.6 2.0 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Rubredoxin_2 PF18073.1 EMC97193.1 - 4.6 7.1 7.7 1.6 8.5 3.1 2.4 2 1 0 2 2 2 0 Rubredoxin metal binding domain 4HBT PF03061.22 EMC97194.1 - 7.1e-05 23.1 0.0 0.074 13.4 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily DUF3253 PF11625.8 EMC97195.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) F-box-like PF12937.7 EMC97195.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 F-box-like SPX PF03105.19 EMC97196.1 - 2.8e-06 27.5 13.6 0.016 15.1 0.1 4.2 3 2 1 4 4 4 3 SPX domain CvfB_WH PF17783.1 EMC97196.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 CvfB-like winged helix domain SUZ PF12752.7 EMC97198.1 - 4.4e-12 46.6 1.6 1.6e-11 44.8 0.4 2.7 2 0 0 2 2 2 1 SUZ domain R3H PF01424.22 EMC97198.1 - 4.3e-06 26.6 0.0 8.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 R3H domain YCII PF03795.14 EMC97199.1 - 0.0036 17.7 0.0 0.0043 17.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain AFG1_ATPase PF03969.16 EMC97200.1 - 2.5e-62 210.9 0.5 6e-28 97.8 0.1 5.1 4 1 1 5 5 5 5 AFG1-like ATPase AAA_5 PF07728.14 EMC97200.1 - 2.9e-05 24.1 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC97200.1 - 7.1e-05 23.3 0.2 0.001 19.5 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMC97200.1 - 0.00021 21.5 0.1 0.00065 20.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EMC97200.1 - 0.00051 20.5 0.0 0.00094 19.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EMC97200.1 - 0.031 13.8 0.1 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 EMC97200.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EMC97200.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 EMC97200.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-patch PF01585.23 EMC97201.1 - 1.1e-06 28.4 0.3 3.1e-06 27.0 0.3 1.8 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EMC97201.1 - 0.0011 18.7 0.9 0.0019 18.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TBX PF12598.8 EMC97201.1 - 0.63 10.9 0.0 0.63 10.9 0.0 3.7 4 1 0 4 4 4 0 T-box transcription factor Zn_clus PF00172.18 EMC97203.1 - 1.7e-09 37.6 9.7 2.7e-09 37.0 9.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMC97203.1 - 0.014 14.2 0.2 0.023 13.5 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Thioredoxin PF00085.20 EMC97204.1 - 3.3e-25 88.1 0.0 4e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EMC97204.1 - 4.3e-08 33.4 0.0 3.3e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EMC97204.1 - 4.8e-06 26.1 0.0 5.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EMC97204.1 - 4.9e-06 26.9 0.4 2.6e-05 24.6 0.4 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EMC97204.1 - 7.1e-05 22.6 0.0 7.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EMC97204.1 - 0.00046 20.1 0.3 0.15 12.0 0.1 2.1 1 1 1 2 2 2 2 AhpC/TSA family HyaE PF07449.11 EMC97204.1 - 0.00091 19.2 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 EMC97204.1 - 0.0013 18.6 0.1 0.0016 18.3 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 EMC97204.1 - 0.0062 16.2 0.2 0.9 9.2 0.0 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_5 PF13743.6 EMC97204.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DIM1 PF02966.16 EMC97204.1 - 0.051 13.4 0.0 0.061 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 EMC97204.1 - 0.063 13.5 0.2 0.14 12.3 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like T6SS_HCP PF05638.12 EMC97205.1 - 1.2e-10 41.9 0.0 1.7e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp RRM_1 PF00076.22 EMC97207.1 - 2.6e-15 56.0 0.0 4.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPS2_interact PF15784.5 EMC97207.1 - 0.065 13.7 1.9 0.098 13.1 1.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain EMP24_GP25L PF01105.24 EMC97207.1 - 0.073 13.0 1.2 0.1 12.5 1.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Wtap PF17098.5 EMC97207.1 - 0.086 12.8 5.5 0.12 12.3 5.5 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family DUF724 PF05266.14 EMC97207.1 - 0.21 11.4 4.8 0.29 11.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ATP-synt_E PF05680.12 EMC97207.1 - 0.22 11.9 2.3 0.32 11.4 2.3 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF4140 PF13600.6 EMC97207.1 - 0.74 10.3 3.6 1.2 9.6 3.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 EMC97207.1 - 1.1 9.8 9.8 1.5 9.3 9.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 EMC97207.1 - 2.2 8.1 4.5 3.5 7.5 4.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Aldo_ket_red PF00248.21 EMC97208.1 - 3e-71 240.0 0.0 3.4e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 EMC97209.1 - 6.1e-09 35.3 38.4 6.1e-09 35.3 38.4 3.3 3 1 0 3 3 3 1 Major Facilitator Superfamily Rtt106 PF08512.12 EMC97211.1 - 7.6e-31 106.4 0.0 1.6e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EMC97211.1 - 1e-07 32.0 0.0 1.8e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Tub_N PF16322.5 EMC97211.1 - 2.1 8.7 17.5 4.1 7.7 14.7 2.2 2 0 0 2 2 2 0 Tubby N-terminal Secretin_N_2 PF07655.13 EMC97212.1 - 0.33 11.5 8.8 0.93 10.1 8.8 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain DNAP_B_exo_N PF08452.10 EMC97213.1 - 0.08 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal Ufd2P_core PF10408.9 EMC97218.1 - 2.6e-212 706.8 2.7 3.2e-212 706.5 2.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EMC97218.1 - 1.2e-28 99.1 1.1 3.3e-28 97.7 1.1 1.8 1 0 0 1 1 1 1 U-box domain Mad3_BUB1_I PF08311.12 EMC97218.1 - 0.1 12.6 0.2 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 NPV_P10 PF05531.12 EMC97218.1 - 0.11 13.0 0.1 0.45 11.0 0.1 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SMN PF06003.12 EMC97220.1 - 0.001 18.4 10.6 0.0092 15.3 1.9 2.8 1 1 2 3 3 3 2 Survival motor neuron protein (SMN) RP854 PF17460.2 EMC97220.1 - 0.19 11.5 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein RP854 RRM_1 PF00076.22 EMC97221.1 - 6.4e-12 45.1 0.0 1.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMC97221.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4094 PF13334.6 EMC97222.1 - 0.092 13.2 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CsiV PF10972.8 EMC97222.1 - 0.094 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV NTF2 PF02136.20 EMC97222.1 - 0.15 12.7 0.0 0.21 12.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF3120 PF11318.8 EMC97222.1 - 0.25 11.6 0.0 0.36 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Ribonuc_red_lgC PF02867.15 EMC97223.1 - 3e-188 626.6 0.0 3.9e-188 626.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EMC97223.1 - 3.3e-24 84.7 0.1 8e-24 83.5 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EMC97223.1 - 7.6e-17 61.7 0.0 2.1e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain CTP_transf_like PF01467.26 EMC97225.1 - 6e-21 75.1 0.0 9.6e-19 68.0 0.0 2.9 3 0 0 3 3 3 2 Cytidylyltransferase-like CHD5 PF04420.14 EMC97226.1 - 4.3e-59 198.9 0.6 5.1e-59 198.7 0.6 1.0 1 0 0 1 1 1 1 CHD5-like protein F-box PF00646.33 EMC97227.1 - 0.011 15.6 0.4 0.035 14.0 0.0 2.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EMC97227.1 - 0.029 14.3 0.1 0.029 14.3 0.1 1.9 2 0 0 2 2 2 0 F-box-like DUF647 PF04884.14 EMC97228.1 - 3.6e-101 337.8 0.9 5.2e-101 337.3 0.9 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF2749 PF10907.8 EMC97229.1 - 0.14 12.4 0.2 0.25 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) NCBP3 PF10309.9 EMC97230.1 - 1.1e-17 63.7 0.2 1.8e-17 63.0 0.2 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 EMC97230.1 - 0.17 12.0 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 RNA binding domain DUF3435 PF11917.8 EMC97231.1 - 8.4e-110 367.6 0.5 1.1e-109 367.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) SF1-HH PF16275.5 EMC97231.1 - 0.017 15.4 0.5 0.042 14.2 0.5 1.7 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain Phage_integrase PF00589.22 EMC97231.1 - 0.44 10.3 4.5 9.9 5.9 0.0 3.3 3 1 0 3 3 3 0 Phage integrase family AAA_23 PF13476.6 EMC97234.1 - 0.011 16.3 8.2 0.023 15.2 8.2 1.6 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.13 EMC97234.1 - 1.5 9.5 12.0 8.1 7.1 12.0 2.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) UPF0242 PF06785.11 EMC97234.1 - 1.7 8.7 22.5 3.6 7.7 22.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1640 PF07798.11 EMC97234.1 - 1.8 8.6 17.7 3.4 7.7 17.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Exonuc_VII_L PF02601.15 EMC97234.1 - 3.5 7.1 19.3 0.23 11.0 14.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit GREB1 PF15782.5 EMC97236.1 - 0.15 9.1 0.0 0.19 8.8 0.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Trns_repr_metal PF02583.17 EMC97236.1 - 0.17 12.2 1.3 0.51 10.7 0.2 2.3 2 1 0 2 2 2 0 Metal-sensitive transcriptional repressor OTT_1508_deam PF14441.6 EMC97237.1 - 5.6e-20 71.1 1.7 1.5e-19 69.8 1.7 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase dsrm PF00035.26 EMC97238.1 - 0.00011 22.8 0.0 0.00018 22.1 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif TPD PF14811.6 EMC97240.1 - 2.5e-12 46.9 0.0 8e-12 45.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function TPD sequence-motif YscO PF07321.12 EMC97241.1 - 2.2e-06 27.7 10.2 2.2e-06 27.7 10.2 1.6 2 0 0 2 2 2 1 Type III secretion protein YscO BORCS8 PF10167.9 EMC97241.1 - 0.003 17.5 0.9 0.0071 16.3 0.9 1.6 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 OEP PF02321.18 EMC97241.1 - 0.018 14.9 6.0 0.029 14.2 6.0 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein Alanine_zipper PF11839.8 EMC97241.1 - 0.021 15.2 0.9 0.021 15.2 0.9 2.2 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein SNARE PF05739.19 EMC97241.1 - 0.11 12.5 2.3 0.16 12.0 1.1 1.9 1 1 0 1 1 1 0 SNARE domain FliJ PF02050.16 EMC97241.1 - 0.18 12.0 9.2 0.36 11.1 9.2 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein COG2 PF06148.11 EMC97241.1 - 0.55 10.3 4.0 1.1 9.3 4.0 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 YscO-like PF16789.5 EMC97241.1 - 0.6 10.1 10.4 0.86 9.6 9.5 1.7 1 1 0 1 1 1 0 YscO-like protein DUF2203 PF09969.9 EMC97241.1 - 1.2 9.8 6.8 0.98 10.2 4.6 1.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) LPP PF04728.13 EMC97241.1 - 1.7 9.1 8.6 0.98 9.9 4.8 2.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Spc7 PF08317.11 EMC97241.1 - 2.5 6.9 10.4 3.3 6.5 9.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DHR10 PF18595.1 EMC97241.1 - 4.5 7.3 15.5 0.19 11.8 8.2 2.3 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DNA_pol_A_exo1 PF01612.20 EMC97242.1 - 1.5e-12 47.6 0.0 2.9e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease OTT_1508_deam PF14441.6 EMC97243.1 - 8.2e-11 41.8 0.1 1.5e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase RIX1 PF08167.12 EMC97243.1 - 0.074 12.8 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Dynamin_N PF00350.23 EMC97245.1 - 2.1e-29 102.7 0.0 5.1e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EMC97245.1 - 5.1e-16 58.7 0.1 1.3e-15 57.4 0.1 1.6 1 1 1 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EMC97245.1 - 0.00058 19.9 0.0 0.0027 17.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2267 PF10025.9 EMC97245.1 - 0.015 15.6 0.1 0.059 13.7 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) LemA PF04011.12 EMC97245.1 - 0.034 14.0 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 LemA family GED PF02212.18 EMC97245.1 - 0.078 13.1 0.2 1 9.6 0.0 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_29 PF13555.6 EMC97245.1 - 0.099 12.4 0.2 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ank_2 PF12796.7 EMC97248.1 - 1.7e-16 60.6 0.0 2.5e-07 31.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC97248.1 - 3.1e-15 56.3 0.3 0.0035 17.9 0.0 5.8 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC97248.1 - 4.2e-15 54.3 3.7 0.0015 18.9 0.1 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EMC97248.1 - 8.2e-13 48.3 1.1 0.00025 21.3 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EMC97248.1 - 9.2e-10 38.5 6.3 0.0033 17.8 0.2 5.4 6 0 0 6 6 6 3 Ankyrin repeat SDA1 PF05285.12 EMC97249.1 - 0.00062 19.3 15.0 0.036 13.5 1.1 2.1 2 0 0 2 2 2 2 SDA1 Sigma70_ner PF04546.13 EMC97249.1 - 0.0027 17.6 13.9 0.013 15.3 0.7 2.6 3 0 0 3 3 3 2 Sigma-70, non-essential region FAM176 PF14851.6 EMC97249.1 - 0.0058 16.3 14.9 0.021 14.5 4.4 2.4 2 0 0 2 2 2 2 FAM176 family SGT1 PF07093.11 EMC97249.1 - 0.0073 14.8 10.1 0.08 11.4 1.6 2.1 2 0 0 2 2 2 2 SGT1 protein RXT2_N PF08595.11 EMC97249.1 - 0.015 15.3 15.1 0.036 14.1 2.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal BUD22 PF09073.10 EMC97249.1 - 0.018 14.4 14.0 0.027 13.8 14.0 1.2 1 0 0 1 1 1 0 BUD22 Acetyltransf_11 PF13720.6 EMC97249.1 - 0.053 14.0 1.1 0.15 12.5 1.1 1.8 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF4611 PF15387.6 EMC97249.1 - 0.09 13.0 16.7 0.051 13.8 2.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF1115 PF06544.12 EMC97249.1 - 0.14 12.2 5.1 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) Peptidase_C37 PF05416.12 EMC97249.1 - 0.18 10.3 3.8 0.25 9.8 3.8 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Spt5_N PF11942.8 EMC97249.1 - 0.26 12.3 26.6 2 9.5 6.9 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.12 EMC97249.1 - 0.37 10.1 26.8 0.33 10.2 7.4 2.1 2 0 0 2 2 2 0 NOA36 protein GEN1_C PF18380.1 EMC97249.1 - 0.41 11.6 11.1 0.93 10.4 1.3 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain BSP_II PF05432.11 EMC97249.1 - 0.8 9.3 20.9 3.5 7.2 20.9 1.8 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) RPA43_OB PF17875.1 EMC97249.1 - 0.8 10.3 7.1 1.1 9.9 0.3 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Slu7 PF11708.8 EMC97249.1 - 1.2 8.8 17.6 1.2 8.8 6.5 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor CENP-B_dimeris PF09026.10 EMC97249.1 - 1.5 9.2 27.0 3.3 8.1 9.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFB6 PF17110.5 EMC97249.1 - 2.2 8.0 14.3 3.9 7.2 3.3 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DDRGK PF09756.9 EMC97249.1 - 2.6 7.6 13.4 0.21 11.2 5.4 2.1 2 0 0 2 2 2 0 DDRGK domain DUF2457 PF10446.9 EMC97249.1 - 3.9 6.5 31.5 2.6 7.1 6.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Presenilin PF01080.17 EMC97249.1 - 4.1 6.1 9.3 6.6 5.4 9.3 1.3 1 0 0 1 1 1 0 Presenilin Pox_RNA_Pol_19 PF05320.12 EMC97249.1 - 5.7 6.9 15.8 9.7 6.1 5.0 2.8 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit FYDLN_acid PF09538.10 EMC97249.1 - 6.9 7.4 22.0 3.5 8.3 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4637 PF15470.6 EMC97249.1 - 9.4 5.9 22.1 3.4 7.4 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) AA_permease_2 PF13520.6 EMC97253.1 - 4.3e-36 124.6 39.4 5.5e-36 124.3 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC97253.1 - 3.8e-09 35.7 36.0 1.5e-08 33.7 36.0 1.8 1 1 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 EMC97262.1 - 9.5e-07 28.8 14.2 1.9e-06 27.9 14.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 EMC97263.1 - 1.7e-10 41.2 0.0 7.6e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMC97263.1 - 4.7e-09 36.2 0.0 1.8e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF4455 PF14643.6 EMC97266.1 - 0.097 11.3 21.0 0.11 11.2 21.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF4268 PF14088.6 EMC97266.1 - 0.44 10.4 11.8 2 8.3 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4268) DUF4192 PF13830.6 EMC97266.1 - 0.53 10.3 9.7 0.57 10.2 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Baculo_PEP_C PF04513.12 EMC97266.1 - 0.54 10.3 5.9 0.66 10.0 5.9 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nas2_N PF18265.1 EMC97266.1 - 0.57 10.1 15.9 3.1 7.8 6.2 2.5 1 1 1 2 2 2 0 Nas2 N_terminal domain MRP-L46 PF11788.8 EMC97266.1 - 1.1 10.0 12.6 1.3 9.8 12.6 1.1 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 DUF1043 PF06295.12 EMC97266.1 - 1.5 8.9 20.4 1.8 8.6 20.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) ZnuA PF01297.17 EMC97266.1 - 2.3 7.6 6.6 2.7 7.4 6.6 1.0 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF883 PF05957.13 EMC97266.1 - 3.8 8.2 11.4 5.3 7.7 11.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 EMC97266.1 - 4.1 5.2 11.6 4.1 5.2 11.6 1.0 1 0 0 1 1 1 0 Prominin DUF4132 PF13569.6 EMC97266.1 - 5 6.9 16.3 4.9 6.9 9.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4132) YniB PF14002.6 EMC97266.1 - 7.7 6.3 6.9 10 5.9 6.9 1.2 1 0 0 1 1 1 0 YniB-like protein MRP-S26 PF14943.6 EMC97266.1 - 7.9 6.4 22.1 8.2 6.3 22.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2368 PF10166.9 EMC97266.1 - 8 6.1 28.4 9.4 5.9 21.8 2.0 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2368) Mitofilin PF09731.9 EMC97266.1 - 8.7 5.1 23.2 9.7 4.9 23.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MPM1 PF17234.2 EMC97266.1 - 9.4 6.5 12.8 11 6.2 12.8 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 EST1_DNA_bind PF10373.9 EMC97267.1 - 0.0066 16.0 0.2 0.033 13.7 0.2 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain DUF1678 PF07913.11 EMC97267.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) YMF19 PF02326.15 EMC97273.1 - 1.1 10.0 4.1 17 6.3 0.8 2.1 2 0 0 2 2 2 0 Plant ATP synthase F0 DDE_1 PF03184.19 EMC97278.1 - 3.8e-29 101.6 0.0 4.5e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EMC97278.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Ank_2 PF12796.7 EMC97279.1 - 3.2e-06 27.6 0.0 4.4e-06 27.2 0.0 1.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EMC97279.1 - 0.00023 21.5 0.0 0.64 10.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EMC97279.1 - 0.00032 21.2 0.0 0.00048 20.6 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC97279.1 - 0.064 13.8 0.0 15 6.5 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat E1-E2_ATPase PF00122.20 EMC97282.1 - 1.8e-42 144.9 4.2 1.8e-42 144.9 4.2 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMC97282.1 - 6.2e-28 98.5 0.0 1.1e-27 97.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EMC97282.1 - 2.1e-08 34.5 0.1 5.6e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EMC97282.1 - 0.00053 19.8 0.0 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMC97283.1 - 5.1e-16 59.6 0.0 7.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMC97283.1 - 4.8e-05 23.2 0.0 0.00038 20.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1593 PF07632.11 EMC97285.1 - 0.027 13.9 0.1 0.031 13.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) Herpes_gE PF02480.16 EMC97286.1 - 0.024 13.4 0.4 0.039 12.7 0.4 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E F-box-like PF12937.7 EMC97288.1 - 0.00013 21.8 0.2 0.00013 21.8 0.2 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EMC97288.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 1.9 2 0 0 2 2 2 1 F-box domain SUR7 PF06687.12 EMC97290.1 - 2.6e-12 46.8 7.7 3.2e-12 46.6 7.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 EMC97290.1 - 0.049 13.5 6.9 0.059 13.2 0.1 2.5 2 0 0 2 2 2 0 Amastin surface glycoprotein DnaJ PF00226.31 EMC97291.1 - 2.2e-11 43.7 2.9 2.2e-11 43.7 2.9 2.5 2 0 0 2 2 2 1 DnaJ domain FAD_binding_8 PF08022.12 EMC97298.1 - 0.00022 21.3 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.19 EMC97298.1 - 0.038 14.1 24.5 0.15 12.2 13.8 3.7 1 1 1 2 2 2 0 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMC97298.1 - 0.09 12.9 0.1 0.4 10.8 0.1 2.0 1 1 0 1 1 1 0 Ferric reductase NAD binding domain COX7a PF02238.15 EMC97299.1 - 0.037 14.4 0.1 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII DUF3723 PF12520.8 EMC97300.1 - 4.1e-92 309.5 2.5 1.2e-74 251.9 0.3 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3723) DUF1214 PF06742.11 EMC97300.1 - 0.13 12.8 0.2 0.88 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1214) Tash_PEST PF07708.11 EMC97300.1 - 0.22 11.7 0.7 0.52 10.5 0.7 1.7 1 0 0 1 1 1 0 Tash protein PEST motif Patatin PF01734.22 EMC97301.1 - 5.3e-11 43.1 2.6 1.1e-06 29.0 0.3 3.3 2 1 0 3 3 3 2 Patatin-like phospholipase zf-C3HC4 PF00097.25 EMC97301.1 - 1.4 8.9 6.4 5.7 6.9 6.4 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC97301.1 - 7.1 6.7 12.1 0.96 9.5 5.9 2.6 2 0 0 2 2 2 0 zinc-RING finger domain THOC7 PF05615.13 EMC97303.1 - 0.00065 20.0 2.0 0.0012 19.1 2.0 1.6 1 0 0 1 1 1 1 Tho complex subunit 7 LPP PF04728.13 EMC97303.1 - 0.026 14.9 1.1 4.2 7.8 0.0 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper NYD-SP28 PF14772.6 EMC97303.1 - 0.048 13.7 1.1 0.048 13.7 1.1 2.3 2 0 0 2 2 2 0 Sperm tail DUF641 PF04859.12 EMC97303.1 - 0.1 12.9 3.1 0.21 11.9 3.1 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF3584 PF12128.8 EMC97303.1 - 0.35 8.3 14.3 0.44 8.0 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cortex-I_coil PF09304.10 EMC97303.1 - 0.82 9.9 5.1 0.52 10.6 0.6 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil TMPIT PF07851.13 EMC97303.1 - 1.4 8.1 4.0 1.1 8.4 2.2 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF4472 PF14739.6 EMC97303.1 - 5.4 7.8 9.4 12 6.7 4.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF1043 PF06295.12 EMC97304.1 - 0.051 13.6 3.1 0.053 13.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) GoLoco PF02188.17 EMC97304.1 - 5.4 6.6 18.8 8.3 6.0 1.9 3.8 3 0 0 3 3 3 0 GoLoco motif zf-RING_2 PF13639.6 EMC97308.1 - 3.8e-09 36.7 6.2 3.8e-09 36.7 6.2 2.3 2 1 0 2 2 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EMC97308.1 - 5.5e-05 23.1 3.1 5.5e-05 23.1 3.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EMC97308.1 - 0.00027 20.8 5.6 0.00027 20.8 5.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 EMC97308.1 - 0.0015 18.3 7.5 0.0037 17.0 7.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EMC97308.1 - 0.0018 18.1 5.3 0.0018 18.1 5.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMC97308.1 - 0.0029 17.9 6.6 0.0077 16.5 6.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain SWIM PF04434.17 EMC97308.1 - 0.0034 17.0 1.5 0.0096 15.6 1.5 1.8 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_UBOX PF13445.6 EMC97308.1 - 0.005 16.8 2.8 0.012 15.6 2.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EMC97308.1 - 0.013 15.3 3.1 0.013 15.3 3.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC97308.1 - 0.017 15.0 5.3 0.017 15.0 5.3 2.2 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EMC97308.1 - 0.025 14.7 6.9 0.059 13.5 6.9 1.7 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 EMC97308.1 - 0.029 14.3 8.1 0.035 14.0 5.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 EMC97308.1 - 0.032 14.1 6.1 0.078 12.9 6.1 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 EMC97308.1 - 0.089 12.7 9.4 0.11 12.4 0.5 2.8 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 EMC97308.1 - 0.62 10.2 5.5 0.97 9.6 1.2 2.7 2 1 1 3 3 3 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 EMC97308.1 - 0.79 9.7 6.1 0.27 11.2 1.8 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) FANCL_C PF11793.8 EMC97308.1 - 1.1 9.5 13.7 0.52 10.5 9.5 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain Ecm33 PF12454.8 EMC97309.1 - 3.3e-12 46.3 3.6 3.3e-12 46.3 3.6 2.0 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 EMC97309.1 - 6.7e-06 26.2 2.5 0.069 13.3 0.0 4.0 1 1 4 5 5 5 2 Receptor L domain DUF5429 PF17494.2 EMC97310.1 - 0.024 14.6 1.3 0.054 13.5 1.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5429) DUF908 PF06012.12 EMC97310.1 - 0.09 12.2 1.0 0.12 11.8 1.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Anp1 PF03452.14 EMC97312.1 - 8.6e-108 359.7 0.0 1e-107 359.5 0.0 1.0 1 0 0 1 1 1 1 Anp1 Pep3_Vps18 PF05131.14 EMC97314.1 - 5.5e-45 152.8 0.0 4.3e-44 149.9 0.0 2.4 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EMC97314.1 - 7.6e-08 32.3 7.4 2.6e-07 30.6 2.0 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 EMC97314.1 - 0.0017 18.3 3.0 0.0042 17.0 0.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EMC97314.1 - 0.004 16.7 0.2 0.01 15.4 0.2 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EMC97314.1 - 0.0066 16.2 2.2 0.02 14.6 2.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger Vps39_2 PF10367.9 EMC97314.1 - 0.0094 16.4 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 TPR_19 PF14559.6 EMC97314.1 - 0.084 13.4 0.1 0.084 13.4 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 EMC97314.1 - 0.094 13.0 0.5 0.27 11.6 0.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EMC97314.1 - 0.28 11.2 0.1 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EMC97314.1 - 1.6 8.7 4.6 0.78 9.7 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EMC97314.1 - 3.4 7.8 5.9 0.3 11.2 0.6 1.9 2 0 0 2 2 2 0 Zinc-finger SNF2_N PF00176.23 EMC97315.1 - 1.8e-53 181.5 0.4 3.5e-52 177.3 0.1 2.6 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC97315.1 - 1.6e-16 60.6 0.0 1.7e-15 57.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EMC97315.1 - 4.3e-08 32.9 6.3 4.3e-08 32.9 6.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC97315.1 - 6.6e-05 22.7 5.4 6.6e-05 22.7 5.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EMC97315.1 - 9e-05 21.5 0.1 0.00027 19.9 0.0 1.7 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 EMC97315.1 - 0.00025 21.3 6.9 0.00025 21.3 6.9 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMC97315.1 - 0.0006 19.6 6.0 0.0006 19.6 6.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EMC97315.1 - 0.00062 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.6 EMC97315.1 - 0.0031 17.6 6.2 0.0031 17.6 6.2 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMC97315.1 - 0.0068 16.3 7.2 0.0068 16.3 7.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 EMC97315.1 - 0.0072 16.3 11.7 0.1 12.6 3.8 2.6 2 0 0 2 2 2 2 Transposase zinc-binding domain zf-RING_UBOX PF13445.6 EMC97315.1 - 0.019 15.0 4.9 0.019 15.0 4.9 2.3 2 0 0 2 2 1 0 RING-type zinc-finger DRAT PF07357.11 EMC97315.1 - 0.019 14.2 0.1 0.079 12.1 0.0 1.9 2 0 0 2 2 2 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) PTA_PTB PF01515.19 EMC97315.1 - 0.046 13.0 0.2 0.29 10.4 0.0 2.1 2 0 0 2 2 2 0 Phosphate acetyl/butaryl transferase DUF4316 PF14195.6 EMC97315.1 - 0.15 11.8 0.3 0.6 9.9 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) zf-rbx1 PF12678.7 EMC97315.1 - 1.5 9.1 10.3 0.18 12.1 3.6 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain RNHCP PF12647.7 EMC97315.1 - 2.3 8.3 10.6 4.1 7.4 2.3 2.6 2 0 0 2 2 2 0 RNHCP domain Prok-RING_4 PF14447.6 EMC97315.1 - 7 6.6 17.2 0.071 13.0 6.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Med18 PF09637.10 EMC97316.1 - 3e-34 119.0 0.0 4.8e-33 115.0 0.0 1.9 1 1 0 1 1 1 1 Med18 protein S36_mt PF10937.8 EMC97317.1 - 3.4e-42 144.7 0.9 3.9e-42 144.5 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF202 PF02656.15 EMC97318.1 - 1.9e-13 50.6 5.5 1.9e-13 50.6 5.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 EMC97318.1 - 1 9.3 10.7 0.12 12.2 5.2 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5337) Tctex-1 PF03645.13 EMC97319.1 - 1.7e-38 131.0 0.0 1.9e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M24 PF00557.24 EMC97320.1 - 1.1e-41 142.9 0.2 1.7e-41 142.3 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 EMC97320.1 - 0.014 14.1 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase Med3 PF11593.8 EMC97320.1 - 1.4 8.0 4.6 2.7 7.1 4.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ytp1 PF10355.9 EMC97321.1 - 6.2e-72 242.1 26.2 6.5e-72 242.0 18.8 2.7 2 1 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EMC97321.1 - 3.9e-31 107.0 2.2 3.9e-31 107.0 2.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DHHC PF01529.20 EMC97321.1 - 7.1 6.7 8.3 0.62 10.2 0.4 2.8 2 1 0 2 2 2 0 DHHC palmitoyltransferase Sacchrp_dh_C PF16653.5 EMC97322.1 - 1.1e-93 314.2 0.0 1.9e-93 313.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EMC97322.1 - 1.7e-23 83.3 0.5 2.4e-23 82.8 0.5 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EMC97322.1 - 4.4e-06 26.8 0.1 1.4e-05 25.2 0.1 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 EMC97322.1 - 0.012 15.2 0.1 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 EMC97322.1 - 0.05 14.0 0.2 0.11 12.9 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 EMC97322.1 - 0.14 12.9 0.1 0.27 12.1 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DER1 PF04511.15 EMC97323.1 - 1.9e-32 112.7 4.2 2.3e-32 112.5 4.2 1.0 1 0 0 1 1 1 1 Der1-like family NAD_kinase PF01513.21 EMC97324.1 - 3.3e-39 134.8 0.0 2.6e-38 131.9 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase Mso1_Sec1_bdg PF14475.6 EMC97324.1 - 0.17 11.5 0.1 0.33 10.6 0.1 1.5 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Acyltransferase PF01553.21 EMC97325.1 - 3.6e-26 91.4 0.0 6e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EMC97325.1 - 2.4e-16 59.6 0.2 5.1e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus ApbA_C PF08546.11 EMC97327.1 - 1.5e-28 99.5 0.0 2.2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EMC97327.1 - 9.5e-22 77.3 0.0 1.7e-20 73.2 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ATG101 PF07855.12 EMC97328.1 - 9.5e-47 158.8 0.1 1.1e-46 158.6 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 HATPase_c PF02518.26 EMC97329.1 - 4e-23 82.1 0.1 2e-22 79.8 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMC97329.1 - 5.3e-16 58.8 0.1 4.3e-14 52.6 0.1 2.9 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EMC97329.1 - 2.7e-14 52.9 0.0 1.1e-13 50.9 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EMC97329.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ORC6 PF05460.13 EMC97330.1 - 0.024 13.9 3.4 0.027 13.7 3.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3592 PF12158.8 EMC97331.1 - 0.05 13.6 0.1 0.063 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) HALZ PF02183.18 EMC97331.1 - 0.081 13.2 0.4 0.16 12.2 0.4 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Epimerase PF01370.21 EMC97332.1 - 0.00089 18.8 0.0 0.019 14.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EMC97332.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EMC97332.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EMC97332.1 - 0.03 14.6 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EMC97332.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.8 1 1 1 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.6 EMC97332.1 - 0.034 14.0 0.0 0.058 13.3 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 EMC97332.1 - 0.039 14.1 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EMC97332.1 - 0.16 11.1 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein PAN_4 PF14295.6 EMC97333.1 - 1.2e-22 79.5 16.5 8.6e-08 32.0 0.6 4.8 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 EMC97333.1 - 2.2e-12 46.8 13.4 0.00057 19.8 0.5 5.1 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 EMC97333.1 - 0.081 13.1 16.9 3.6 7.8 0.7 5.0 4 0 0 4 4 4 0 PAN-like domain Pept_tRNA_hydro PF01195.19 EMC97334.1 - 5.3e-38 130.6 0.0 6.6e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Usher_TcfC PF17271.2 EMC97334.1 - 0.012 14.4 0.1 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 TcfC Usher-like barrel domain MOSC PF03473.17 EMC97335.1 - 6.4e-24 84.4 0.0 1.2e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EMC97335.1 - 2.4e-16 59.7 0.0 4.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Cuticle_1 PF08140.11 EMC97335.1 - 0.031 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Zn_clus PF00172.18 EMC97336.1 - 3e-10 40.1 12.7 5.5e-10 39.2 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMC97336.1 - 1e-08 34.4 0.3 2.2e-05 23.5 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain C1_2 PF03107.16 EMC97339.1 - 0.0017 18.6 8.3 0.0022 18.3 8.3 1.1 1 0 0 1 1 1 1 C1 domain zf-HIT PF04438.16 EMC97339.1 - 0.003 17.4 5.4 0.003 17.4 5.4 1.6 2 0 0 2 2 2 1 HIT zinc finger FeS PF04060.13 EMC97339.1 - 0.083 12.6 3.7 0.083 12.6 3.7 1.7 2 0 0 2 2 2 0 Putative Fe-S cluster zf-B_box PF00643.24 EMC97339.1 - 0.11 12.7 8.1 0.3 11.3 8.1 1.8 1 1 0 1 1 1 0 B-box zinc finger Zn_ribbon_SprT PF17283.2 EMC97339.1 - 0.6 10.1 9.7 0.77 9.7 3.3 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EMC97339.1 - 2.5 8.3 11.1 13 6.0 0.3 2.7 2 2 0 2 2 2 0 Zinc ribbon domain Pkinase PF00069.25 EMC97341.1 - 6.2e-48 163.5 0.0 1e-47 162.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97341.1 - 2e-27 96.1 0.0 2.7e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC97341.1 - 0.0039 16.6 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SSB PF00436.25 EMC97343.1 - 4e-16 58.9 0.0 4.9e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4395 PF14340.6 EMC97344.1 - 0.043 14.1 0.1 0.064 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) HSF_DNA-bind PF00447.17 EMC97345.1 - 1e-27 96.6 0.1 2.6e-27 95.2 0.1 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_TATA_bd PF12325.8 EMC97345.1 - 0.0022 18.2 2.4 0.043 14.0 0.3 2.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EMC97345.1 - 0.031 14.8 1.5 0.031 14.8 1.5 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 EMC97345.1 - 0.12 11.2 0.1 0.12 11.2 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EMC97345.1 - 0.28 11.2 2.7 2 8.5 0.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 EMC97345.1 - 0.85 9.9 5.1 1.2 9.4 0.3 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.25 EMC97345.1 - 0.9 9.2 5.8 0.12 12.1 0.3 2.2 3 0 0 3 3 3 0 Syntaxin ORC6 PF05460.13 EMC97346.1 - 1.4e-27 96.9 2.8 7.8e-23 81.3 6.8 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) RPEL PF02755.15 EMC97346.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 RPEL repeat MFS_1 PF07690.16 EMC97348.1 - 1.5e-39 136.0 29.3 5e-38 130.9 19.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC97348.1 - 4.5e-08 32.4 8.2 1.8e-07 30.4 3.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EMC97348.1 - 0.00023 19.7 3.0 0.00034 19.2 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EMC97348.1 - 0.00026 20.0 5.3 0.045 12.6 0.0 2.3 1 1 1 2 2 2 2 MFS_1 like family LacY_symp PF01306.19 EMC97348.1 - 0.031 13.1 7.6 0.1 11.3 3.1 2.3 1 1 1 2 2 2 0 LacY proton/sugar symporter Thioredoxin PF00085.20 EMC97349.1 - 0.00081 19.3 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin EamA PF00892.20 EMC97350.1 - 6.9e-06 26.3 9.9 6.9e-06 26.3 9.9 2.3 2 0 0 2 2 2 1 EamA-like transporter family Multi_Drug_Res PF00893.19 EMC97350.1 - 0.11 13.1 14.5 0.36 11.5 1.3 2.9 2 1 1 3 3 3 0 Small Multidrug Resistance protein MccV PF17508.2 EMC97350.1 - 0.19 12.3 2.3 17 6.1 0.2 2.5 2 0 0 2 2 2 0 Microcin V bacteriocin Cu-oxidase_3 PF07732.15 EMC97352.1 - 6.5e-42 142.3 1.2 1.8e-41 140.9 0.4 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMC97352.1 - 7.8e-33 113.1 7.4 1.4e-27 96.1 1.9 4.3 3 2 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 EMC97352.1 - 4.4e-32 111.4 0.7 1.6e-28 99.8 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase UK PF02512.14 EMC97353.1 - 0.072 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Virulence determinant zf-C2H2 PF00096.26 EMC97356.1 - 7.4e-22 76.5 19.8 3.8e-05 23.9 1.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC97356.1 - 8.6e-19 67.1 24.4 3.6e-09 36.6 0.3 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC97356.1 - 2.7e-10 40.2 18.1 0.0061 17.3 0.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EMC97356.1 - 2.6e-05 24.4 7.3 0.021 15.1 1.1 3.2 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-met PF12874.7 EMC97356.1 - 4.5e-05 23.7 5.6 0.23 11.9 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EMC97356.1 - 0.00053 20.2 7.3 0.25 11.5 0.3 3.3 2 1 1 3 3 3 2 Aberrant zinc-finger RteC PF09357.10 EMC97356.1 - 0.036 13.8 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 RteC protein zf-DNA_Pol PF08996.10 EMC97356.1 - 0.042 13.6 5.3 0.69 9.6 0.9 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf_UBZ PF18439.1 EMC97356.1 - 0.12 12.0 3.1 1.1 8.9 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 EMC97356.1 - 0.16 12.0 0.4 0.16 12.0 0.4 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger C1_4 PF07975.12 EMC97356.1 - 0.23 11.7 3.3 0.54 10.5 0.3 2.7 2 1 0 2 2 2 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 EMC97356.1 - 0.29 11.1 2.4 0.42 10.6 0.1 2.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 EMC97356.1 - 0.82 9.6 12.2 18 5.4 0.9 4.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger FOXP-CC PF16159.5 EMC97356.1 - 1.6 9.4 6.3 12 6.6 0.1 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain Antimicrobial14 PF08109.11 EMC97357.1 - 0.14 12.2 0.4 0.38 10.8 0.2 1.7 2 0 0 2 2 2 0 Lactocin 705 family WD40 PF00400.32 EMC97358.1 - 2.8e-62 205.2 18.0 1.9e-09 38.0 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC97358.1 - 6.8e-21 74.4 0.0 7.2e-05 23.0 0.0 6.1 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 EMC97358.1 - 4.1e-08 33.4 3.7 4.1e-08 33.4 3.7 2.1 2 0 0 2 2 2 1 Tup N-terminal WD40_like PF17005.5 EMC97358.1 - 1.9e-07 30.7 0.0 0.029 13.7 0.0 3.8 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 EMC97358.1 - 4.6e-07 29.1 0.3 0.36 9.7 0.0 5.0 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EMC97358.1 - 2.2e-05 23.2 0.2 0.00039 19.1 0.2 2.4 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.8 EMC97358.1 - 4.4e-05 22.3 0.4 0.43 9.2 0.0 3.7 1 1 3 4 4 4 2 Nucleoporin Nup120/160 MMS1_N PF10433.9 EMC97358.1 - 0.006 15.3 0.0 2 6.9 0.0 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nbas_N PF15492.6 EMC97358.1 - 0.015 14.7 0.1 3.6 6.8 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EMC97358.1 - 0.047 12.4 0.1 18 3.9 0.0 3.3 1 1 2 4 4 4 0 Nup133 N terminal like VID27 PF08553.10 EMC97358.1 - 0.051 12.6 0.0 0.62 9.1 0.0 2.5 1 1 2 3 3 3 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 EMC97358.1 - 0.083 12.9 0.0 58 3.8 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Erf4 PF10256.9 EMC97359.1 - 5.2e-35 120.0 0.0 6.1e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Creatinase_N_2 PF16189.5 EMC97360.1 - 1.8e-51 174.4 0.8 2.6e-50 170.6 0.1 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EMC97360.1 - 1.3e-46 158.9 0.0 2e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EMC97360.1 - 7.4e-24 83.6 0.1 2.2e-23 82.1 0.1 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EMC97360.1 - 1.7e-19 70.8 0.1 2.3e-16 60.7 0.0 2.6 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain ArgJ PF01960.18 EMC97361.1 - 6.1e-145 482.7 1.4 7.1e-145 482.5 1.4 1.0 1 0 0 1 1 1 1 ArgJ family UBA_4 PF14555.6 EMC97362.1 - 0.0004 20.1 0.6 0.00086 19.1 0.1 1.8 2 0 0 2 2 2 1 UBA-like domain UQ_con PF00179.26 EMC97363.1 - 4.5e-38 130.1 0.0 6.1e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EMC97363.1 - 0.05 13.9 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 RWD domain Spo12 PF05032.12 EMC97364.1 - 1.8e-09 37.3 0.9 3e-09 36.6 0.3 1.8 2 0 0 2 2 2 1 Spo12 family DKCLD PF08068.12 EMC97365.1 - 2.1e-32 111.0 0.1 6.6e-31 106.2 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EMC97365.1 - 3.2e-23 82.7 0.1 2.8e-20 73.2 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EMC97365.1 - 2.8e-22 78.6 1.1 5.5e-22 77.7 1.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EMC97365.1 - 3.6e-20 71.7 1.7 7.3e-20 70.7 1.7 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EMC97365.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 UPF0113 PUA domain Ldh_1_N PF00056.23 EMC97366.1 - 9.7e-19 67.9 0.0 1.2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EMC97366.1 - 0.00055 19.0 0.0 0.00064 18.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 EMC97366.1 - 0.029 13.7 0.1 0.33 10.3 0.1 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 EMC97366.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding MFS_1 PF07690.16 EMC97367.1 - 5.3e-33 114.4 30.2 5.3e-33 114.4 30.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily AAA PF00004.29 EMC97368.1 - 6.9e-19 68.6 0.0 1.6e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMC97368.1 - 0.0016 18.9 1.8 0.012 16.0 0.0 2.8 2 2 1 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 EMC97368.1 - 0.003 17.3 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EMC97368.1 - 0.0055 16.2 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EMC97368.1 - 0.018 15.3 0.0 0.06 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMC97368.1 - 0.025 14.9 0.0 0.094 13.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Torsin PF06309.11 EMC97368.1 - 0.059 13.5 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Torsin NMT1 PF09084.11 EMC97369.1 - 2.3e-35 122.5 0.0 2.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EMC97369.1 - 0.00092 19.0 0.0 0.014 15.1 0.0 2.1 1 1 1 2 2 2 1 NMT1-like family HABP4_PAI-RBP1 PF04774.15 EMC97370.1 - 1.6 9.6 7.6 5.8 7.8 7.6 1.9 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family DDA1 PF10172.9 EMC97371.1 - 2.2 8.6 9.9 8.7 6.7 2.1 3.2 2 1 0 2 2 2 0 Det1 complexing ubiquitin ligase Thiolase_N PF00108.23 EMC97373.1 - 2.8e-15 56.4 0.6 1.4e-13 50.8 0.2 2.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMC97373.1 - 1.1e-12 47.7 4.9 2.8e-12 46.4 1.1 3.1 2 1 2 4 4 4 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EMC97373.1 - 2.9e-06 27.1 0.6 0.00012 21.9 0.0 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EMC97373.1 - 8.2e-05 22.3 0.6 0.00015 21.4 0.2 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMC97373.1 - 0.0062 16.5 0.8 0.91 9.5 0.0 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 EMC97373.1 - 0.012 14.3 0.3 0.039 12.7 0.2 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) HMA PF00403.26 EMC97374.1 - 1e-17 64.3 1.8 1.2e-17 64.1 1.8 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain phiKZ_IP PF12699.7 EMC97374.1 - 0.041 13.0 0.1 0.048 12.8 0.1 1.0 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Fer2_BFD PF04324.15 EMC97374.1 - 0.11 12.9 0.4 0.25 11.7 0.1 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain BRO1 PF03097.18 EMC97375.1 - 8e-122 406.8 1.4 8e-122 406.8 1.4 2.5 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EMC97375.1 - 6.2e-80 268.6 8.5 1.6e-79 267.3 8.5 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV PilX_N PF14341.6 EMC97376.1 - 0.12 12.4 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 PilX N-terminal Fungal_trans PF04082.18 EMC97377.1 - 3.2e-27 95.2 0.0 5.1e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC97377.1 - 4e-08 33.3 8.8 8.9e-08 32.1 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 EMC97378.1 - 3e-59 200.7 0.2 4.2e-59 200.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EMC97378.1 - 2.1e-34 118.1 1.7 4.1e-33 113.9 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EMC97378.1 - 1.5e-18 67.1 0.6 5.6e-17 62.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC97378.1 - 1.2e-13 51.0 0.8 2.3e-13 50.1 0.8 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMC97378.1 - 5.4e-05 22.6 0.2 0.094 12.0 0.2 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EMC97378.1 - 5.6e-05 22.5 0.0 9.2e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EMC97378.1 - 0.0043 16.4 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EMC97378.1 - 0.013 15.4 1.2 0.031 14.1 0.0 2.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMC97378.1 - 0.018 14.4 0.3 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LCAT PF02450.15 EMC97378.1 - 0.021 14.0 0.2 0.032 13.4 0.2 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GIDA PF01134.22 EMC97378.1 - 0.029 13.5 1.7 0.21 10.6 0.9 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EMC97378.1 - 0.038 14.2 1.4 0.13 12.6 1.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMC97378.1 - 0.04 13.0 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EMC97378.1 - 0.1 11.9 0.3 0.31 10.2 0.2 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 EMC97378.1 - 0.2 10.7 4.0 1.1 8.3 2.8 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EMC97378.1 - 0.22 10.2 2.8 0.49 9.1 0.5 2.2 2 1 0 2 2 2 0 HI0933-like protein DAO PF01266.24 EMC97378.1 - 4.2 6.8 7.7 0.6 9.6 2.8 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase Ribosom_S12_S23 PF00164.25 EMC97379.1 - 1.1e-50 170.0 0.6 1.4e-50 169.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PIG-P PF08510.12 EMC97380.1 - 1.2e-52 176.9 0.8 1.6e-52 176.6 0.8 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EMC97380.1 - 0.052 13.9 8.0 0.084 13.2 8.0 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PH PF00169.29 EMC97381.1 - 0.0014 19.1 0.0 0.005 17.3 0.0 2.0 1 1 0 1 1 1 1 PH domain LRR_6 PF13516.6 EMC97381.1 - 0.053 13.6 6.7 5.1 7.4 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich repeat Tox-ODYAM1 PF15642.6 EMC97381.1 - 0.19 10.6 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus MFS_2 PF13347.6 EMC97382.1 - 5.3e-09 35.1 3.5 5.3e-09 35.1 3.5 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 EMC97382.1 - 0.0035 16.3 7.4 0.0042 16.0 5.9 1.9 1 1 0 1 1 1 1 MFS_1 like family G6PD_C PF02781.16 EMC97383.1 - 3e-114 381.1 0.0 5.8e-114 380.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EMC97383.1 - 6.1e-63 212.6 0.0 2.3e-62 210.8 0.0 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain HNOBA PF07701.14 EMC97383.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding associated DUF4455 PF14643.6 EMC97383.1 - 0.1 11.2 0.8 0.15 10.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Ribosomal_L35Ae PF01247.18 EMC97384.1 - 1.1e-40 137.7 0.4 1.2e-40 137.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EMC97384.1 - 0.0022 18.1 0.0 0.46 10.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Cytochrom_C550 PF14495.6 EMC97384.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain Brix PF04427.18 EMC97385.1 - 2.1e-38 132.4 0.0 2.7e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.23 EMC97386.1 - 5e-65 219.5 2.0 5e-65 219.5 2.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 EMC97386.1 - 1.5e-45 154.9 15.4 1.5e-45 154.9 15.4 5.1 5 1 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.31 EMC97386.1 - 4.7e-19 68.8 0.0 1e-18 67.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC97386.1 - 3.8e-06 27.0 1.6 8e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EMC97386.1 - 0.0039 17.0 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EMC97386.1 - 0.0073 15.5 1.7 0.031 13.4 0.0 2.7 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Fe_hyd_lg_C PF02906.14 EMC97386.1 - 0.12 12.0 1.1 0.3 10.7 1.1 1.7 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain CDP-OH_P_transf PF01066.21 EMC97387.1 - 1e-14 55.0 0.5 1e-14 55.0 0.5 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF1304 PF06993.12 EMC97387.1 - 0.14 12.1 5.2 0.22 11.5 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1304) Gti1_Pac2 PF09729.9 EMC97388.1 - 8.3e-60 202.0 0.0 2.3e-59 200.5 0.0 1.6 1 1 0 1 1 1 1 Gti1/Pac2 family MIF4G_like PF09088.11 EMC97391.1 - 2.9e-82 275.1 0.5 4.7e-82 274.4 0.5 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EMC97391.1 - 2e-66 224.2 0.0 2.7e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 MIF4G like DUF3736 PF12540.8 EMC97391.1 - 0.12 12.4 0.6 0.3 11.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) G10 PF01125.17 EMC97392.1 - 7e-68 227.0 5.4 7.7e-68 226.8 5.4 1.0 1 0 0 1 1 1 1 G10 protein SNF2_N PF00176.23 EMC97393.1 - 1.8e-73 247.3 0.8 1.8e-73 247.3 0.8 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EMC97393.1 - 3.3e-23 81.6 0.1 9.7e-23 80.1 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 EMC97393.1 - 2.6e-20 72.8 3.7 1.8e-18 66.9 0.0 3.9 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 EMC97393.1 - 1.8e-19 69.8 13.9 1.8e-19 69.8 13.9 4.0 3 1 1 4 4 4 1 HSA SnAC PF14619.6 EMC97393.1 - 2.6e-12 47.2 0.6 2.6e-12 47.2 0.6 3.7 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 EMC97393.1 - 1.2e-11 44.1 1.5 1.2e-11 44.1 1.5 2.8 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 EMC97393.1 - 4.8e-11 43.0 0.1 4.8e-11 43.0 0.1 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chalcone_2 PF16035.5 EMC97393.1 - 0.57 9.9 9.9 0.053 13.3 2.5 2.9 2 1 1 3 3 3 0 Chalcone isomerase like IGPD PF00475.18 EMC97394.1 - 5.5e-60 201.8 0.6 7.6e-60 201.4 0.6 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Complex1_LYR_2 PF13233.6 EMC97395.1 - 0.00057 20.6 0.4 0.00082 20.1 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EMC97395.1 - 0.0028 17.7 0.1 0.0046 17.0 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) R-HINP1I PF11463.8 EMC97395.1 - 0.032 13.7 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease IKKbetaNEMObind PF12179.8 EMC97395.1 - 0.047 13.7 0.1 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Pkinase PF00069.25 EMC97396.1 - 1.1e-65 221.7 0.0 1.3e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97396.1 - 3.1e-24 85.7 0.0 4.1e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC97396.1 - 3.1e-06 26.7 0.0 1.9e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EMC97396.1 - 0.0023 17.9 0.1 0.022 14.7 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EMC97396.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GIDA PF01134.22 EMC97398.1 - 5.8e-157 522.8 0.0 7e-157 522.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EMC97398.1 - 1.5e-69 234.4 0.0 2.1e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EMC97398.1 - 7e-06 25.6 0.5 1.1e-05 25.0 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC97398.1 - 6.9e-05 22.2 0.3 0.00016 21.1 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC97398.1 - 0.0005 19.3 2.0 0.00057 19.1 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EMC97398.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EMC97398.1 - 0.019 14.0 0.1 0.034 13.2 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EMC97398.1 - 0.025 15.1 0.1 0.07 13.7 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC97398.1 - 0.09 11.6 0.4 4.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 EMC97398.1 - 0.18 10.5 3.9 0.43 9.2 0.3 2.6 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 EMC97398.1 - 1.8 8.1 5.9 4.3 6.8 0.0 2.5 1 1 1 2 2 2 0 FAD dependent oxidoreductase Importin_rep_3 PF18806.1 EMC97399.1 - 0.00015 21.7 0.1 0.0029 17.6 0.0 3.2 4 0 0 4 4 4 1 Importin 13 repeat Importin_rep PF18773.1 EMC97399.1 - 0.039 13.7 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Importin 13 repeat HEAT PF02985.22 EMC97399.1 - 0.29 11.5 6.9 19 5.8 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat Phosphodiest PF01663.22 EMC97401.1 - 1.3e-14 54.6 1.0 2.1e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMC97401.1 - 0.00025 20.5 0.0 0.0019 17.7 0.0 2.1 2 0 0 2 2 2 1 Sulfatase RRM_2 PF04059.12 EMC97402.1 - 1.1e-25 89.7 0.0 1.9e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EMC97402.1 - 3.7e-05 23.5 0.3 0.0003 20.5 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EMC97402.1 - 0.012 15.9 0.0 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 BRCA1-associated protein 2 Smg4_UPF3 PF03467.15 EMC97402.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family Sec15 PF04091.12 EMC97403.1 - 5.2e-102 341.5 0.1 1.5e-101 340.0 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 EMC97403.1 - 2.6e-05 24.1 2.6 2.6e-05 24.1 2.6 3.7 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain COG5 PF10392.9 EMC97403.1 - 0.00011 22.4 7.2 0.00011 22.3 4.5 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG2 PF06148.11 EMC97403.1 - 0.00019 21.5 3.9 0.00019 21.5 3.9 2.2 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 EMC97403.1 - 0.017 14.5 5.5 0.036 13.3 5.5 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex NOP5NT PF08156.13 EMC97403.1 - 0.098 13.1 0.1 0.82 10.1 0.1 2.7 2 0 0 2 2 2 0 NOP5NT (NUC127) domain TPR_MLP1_2 PF07926.12 EMC97403.1 - 3 7.9 9.6 0.11 12.6 1.4 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Tom7 PF08038.12 EMC97404.1 - 3.3e-21 74.7 0.1 3.8e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 TOM7 family RRM_1 PF00076.22 EMC97406.1 - 3.8e-31 106.7 0.0 1.8e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMC97406.1 - 0.0068 16.0 0.0 0.047 13.3 0.0 2.1 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC97406.1 - 0.032 14.4 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif OB_RNB PF08206.11 EMC97406.1 - 0.08 12.6 0.4 10 5.9 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF2015 PF09435.10 EMC97407.1 - 8.4e-42 141.6 0.0 1.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Peptidase_C14 PF00656.22 EMC97408.1 - 0.19 11.6 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Caspase domain ALAD PF00490.21 EMC97410.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase BAR PF03114.18 EMC97413.1 - 2.2e-46 158.4 7.7 2.5e-46 158.3 7.7 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EMC97413.1 - 3.4e-05 23.2 3.4 3.9e-05 22.9 3.4 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking OmpH PF03938.14 EMC97413.1 - 0.27 11.5 10.5 0.087 13.2 4.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1501 PF07394.12 EMC97413.1 - 1.1 8.3 5.3 0.93 8.5 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1501) Torus PF16131.5 EMC97414.1 - 2.9e-40 137.3 0.0 4.8e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 EMC97414.1 - 0.00024 21.1 0.6 0.00024 21.1 0.6 1.9 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 EMC97414.1 - 0.0028 17.5 0.9 0.0028 17.5 0.9 1.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EMC97414.1 - 0.46 10.4 6.5 0.1 12.5 2.6 1.8 2 0 0 2 2 2 0 CCCH-type zinc finger CorA PF01544.18 EMC97415.1 - 5e-06 26.0 3.4 1.2e-05 24.8 3.3 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein dCache_1 PF02743.18 EMC97415.1 - 0.94 9.2 4.9 4.1 7.1 0.4 2.1 2 0 0 2 2 2 0 Cache domain Adap_comp_sub PF00928.21 EMC97416.1 - 4.1e-84 282.1 0.0 5e-84 281.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EMC97416.1 - 0.037 14.0 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain muHD PF10291.9 EMC97416.1 - 0.042 13.3 0.2 0.1 12.0 0.2 1.6 1 1 0 1 1 1 0 Muniscin C-terminal mu homology domain WHEP-TRS PF00458.20 EMC97417.1 - 0.21 11.8 1.4 0.44 10.7 1.4 1.5 1 0 0 1 1 1 0 WHEP-TRS domain Ras PF00071.22 EMC97418.1 - 1.1e-46 158.5 0.2 1.2e-46 158.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC97418.1 - 3.7e-15 56.2 0.1 5.1e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC97418.1 - 3.4e-08 33.1 0.0 3.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EMC97418.1 - 4.2e-05 23.5 0.2 0.0093 15.9 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EMC97418.1 - 5e-05 22.8 0.1 6.8e-05 22.4 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EMC97418.1 - 7.4e-05 22.4 0.1 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMC97418.1 - 0.00012 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMC97418.1 - 0.00015 21.3 0.0 0.0034 16.9 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 EMC97418.1 - 0.072 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Elf1 PF05129.13 EMC97420.1 - 5.8e-26 90.4 1.3 7.5e-26 90.0 1.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like GTP_CH_N PF12471.8 EMC97421.1 - 1.3e-89 299.1 0.0 1.8e-89 298.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EMC97421.1 - 5e-17 62.0 0.0 1.4e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase II Pro_isomerase PF00160.21 EMC97422.1 - 6.6e-35 120.7 0.0 1.9e-34 119.2 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ORC_WH_C PF18137.1 EMC97422.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.3 2 1 0 2 2 2 0 Origin recognition complex winged helix C-terminal XAP5 PF04921.14 EMC97422.1 - 4.4 7.1 10.2 0.87 9.4 0.1 2.3 1 1 1 2 2 2 0 XAP5, circadian clock regulator Blt1 PF12754.7 EMC97423.1 - 6.4e-33 114.2 1.0 6.4e-33 114.2 1.0 1.7 2 0 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 EMC97423.1 - 7.6e-18 63.8 0.2 1.3e-17 63.1 0.2 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 EMC97423.1 - 6.4e-05 22.6 0.2 0.00012 21.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 EMC97423.1 - 0.013 15.9 0.2 0.022 15.1 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain SATase_N PF06426.14 EMC97423.1 - 0.045 14.1 0.4 0.1 13.0 0.4 1.6 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Rad60-SLD PF11976.8 EMC97423.1 - 0.063 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DER1 PF04511.15 EMC97424.1 - 5.6e-51 173.2 6.8 6.5e-51 173.0 6.8 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.24 EMC97425.1 - 4.7e-43 146.7 0.1 5.5e-43 146.5 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EMC97425.1 - 3.4e-05 23.9 0.1 4.8e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EMC97425.1 - 0.00026 21.3 0.1 0.00037 20.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EMC97425.1 - 0.0055 17.0 1.0 0.011 16.1 1.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EMC97425.1 - 0.0056 16.8 0.0 0.0077 16.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Flavin_Reduct PF01613.18 EMC97426.1 - 7.2e-13 48.9 0.0 9.8e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain HECT PF00632.25 EMC97426.1 - 0.019 14.5 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Ribosomal_L2_C PF03947.18 EMC97427.1 - 3e-41 140.6 5.6 3e-41 140.6 5.6 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EMC97427.1 - 1.6e-14 53.6 0.1 3.9e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.6 EMC97428.1 - 0.029 13.9 0.0 0.081 12.5 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 MMM1 PF10296.9 EMC97429.1 - 2.9e-139 463.8 0.0 3.7e-139 463.4 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 MFS_1 PF07690.16 EMC97430.1 - 6.3e-22 78.0 46.6 9e-22 77.5 46.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SBF PF01758.16 EMC97431.1 - 7.9e-48 162.7 12.3 7.9e-48 162.7 12.3 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3619 PF12279.8 EMC97431.1 - 0.81 10.0 3.4 3.7 7.9 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3619) FMN_red PF03358.15 EMC97433.1 - 5.2e-24 84.7 0.0 1e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase E1-E2_ATPase PF00122.20 EMC97434.1 - 4.5e-16 58.9 6.6 2.4e-11 43.5 0.3 2.2 1 1 1 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 EMC97434.1 - 3e-13 50.5 0.0 5.3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 EMC97435.1 - 6.7e-28 97.5 0.0 9.5e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC97435.1 - 1.4e-18 67.3 0.0 2.2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMC97435.1 - 9.9e-08 31.7 0.0 2.7e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMC97435.1 - 1.8e-07 31.2 0.0 5.2e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EMC97435.1 - 0.00011 21.4 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMC97435.1 - 0.00061 19.7 0.1 0.0018 18.2 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC97435.1 - 0.0011 18.6 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EMC97435.1 - 0.0025 17.0 0.0 0.0035 16.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Forkhead PF00250.18 EMC97436.1 - 1.1e-34 118.5 0.1 1.8e-34 117.9 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain PhyH PF05721.13 EMC97438.1 - 2.5e-08 34.5 0.2 1.1e-07 32.3 0.2 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.19 EMC97438.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain P21-Arc PF04062.14 EMC97439.1 - 6.3e-73 244.5 0.0 7.1e-73 244.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit GRDP-like PF07173.12 EMC97440.1 - 1.5e-19 71.1 1.1 1.3e-12 48.5 0.1 3.4 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like DDE_Tnp_IS66_C PF13817.6 EMC97440.1 - 0.069 13.4 0.1 3.4 7.9 0.0 3.3 4 0 0 4 4 4 0 IS66 C-terminal element Swi3 PF07962.12 EMC97440.1 - 0.12 12.4 0.1 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 Kelch_6 PF13964.6 EMC97441.1 - 9.2e-06 25.8 2.0 0.19 12.1 0.1 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 EMC97441.1 - 0.0016 18.4 3.3 0.34 11.0 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 EMC97441.1 - 0.0049 16.8 0.4 2.4 8.2 0.1 3.5 3 1 0 3 3 3 2 Galactose oxidase, central domain DUF347 PF03988.12 EMC97441.1 - 0.0063 16.7 0.3 0.021 15.0 0.3 1.9 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) peroxidase PF00141.23 EMC97442.1 - 1.1e-14 54.7 0.0 2.1e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 Peroxidase Aldo_ket_red PF00248.21 EMC97445.1 - 1.1e-38 133.1 0.0 1.1e-36 126.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 EMC97445.1 - 0.13 12.5 0.0 0.84 9.9 0.0 2.1 1 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ydc2-catalyt PF09159.10 EMC97446.1 - 1.7e-60 205.1 0.0 2.2e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EMC97446.1 - 0.01 16.0 0.0 2.8 8.1 0.0 3.1 3 0 0 3 3 3 1 Poxvirus A22 protein SAP PF02037.27 EMC97446.1 - 0.1 12.4 0.1 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 SAP domain LsmAD PF06741.13 EMC97447.1 - 4.5e-29 100.8 2.6 4.5e-29 100.8 2.6 2.4 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 EMC97447.1 - 1.8e-14 53.6 0.1 3.4e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain NatB_MDM20 PF09797.9 EMC97447.1 - 0.25 10.2 1.6 0.39 9.6 1.6 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit LAT PF15234.6 EMC97448.1 - 1.3 8.7 5.6 1.5 8.5 5.6 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells AIP3 PF03915.13 EMC97450.1 - 7.8e-141 469.9 0.0 1.3e-140 469.1 0.0 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 HSBP1 PF06825.12 EMC97450.1 - 0.034 14.0 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Syntaxin-6_N PF09177.11 EMC97450.1 - 0.035 14.7 6.6 0.2 12.2 2.3 3.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Med11 PF10280.9 EMC97450.1 - 0.037 14.5 2.3 0.21 12.1 0.1 3.0 2 1 0 2 2 2 0 Mediator complex protein MIP-T3_C PF17749.1 EMC97450.1 - 0.13 12.3 0.8 1.4 8.9 0.1 2.8 1 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Spc7 PF08317.11 EMC97450.1 - 0.28 10.0 2.7 0.49 9.2 0.6 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein Lectin_N PF03954.14 EMC97450.1 - 2.6 7.8 4.5 15 5.3 3.1 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain adh_short_C2 PF13561.6 EMC97451.1 - 4.2e-42 144.3 2.1 5.2e-42 144.0 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC97451.1 - 1.3e-38 132.4 0.3 1.7e-38 132.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC97451.1 - 4.9e-16 59.2 0.6 8e-16 58.5 0.6 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMC97451.1 - 0.0021 17.2 0.1 0.0032 16.6 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EMC97451.1 - 0.032 13.3 0.0 0.076 12.0 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EMC97451.1 - 0.075 12.5 0.2 0.24 10.8 0.2 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Med5 PF08689.10 EMC97452.1 - 2.3e-63 214.6 0.0 3e-62 210.8 0.0 2.3 1 1 0 1 1 1 1 Mediator complex subunit Med5 Aa_trans PF01490.18 EMC97454.1 - 1.2e-76 258.1 28.2 1.4e-76 257.8 28.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Epimerase PF01370.21 EMC97455.1 - 4.2e-09 36.2 0.3 0.0026 17.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC97455.1 - 2.7e-05 24.1 0.4 5e-05 23.3 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EMC97455.1 - 0.00069 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EMC97455.1 - 0.0012 18.5 0.1 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Sec23_trunk PF04811.15 EMC97458.1 - 3.7e-80 269.0 0.0 5.7e-80 268.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EMC97458.1 - 1.6e-29 102.5 0.1 3.8e-29 101.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EMC97458.1 - 1.2e-25 89.3 0.3 3.8e-25 87.7 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EMC97458.1 - 4.9e-15 55.3 6.0 9.6e-15 54.4 6.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EMC97458.1 - 4.5e-12 45.7 0.0 1.1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat RasGEF PF00617.19 EMC97459.1 - 5e-52 176.7 0.9 1.5e-51 175.1 0.1 2.3 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EMC97459.1 - 4e-17 62.4 0.0 1.5e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 EMC97459.1 - 0.00019 21.0 0.0 0.00056 19.5 0.0 1.9 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMC97459.1 - 0.00028 20.7 0.0 0.00067 19.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 EMC97459.1 - 0.048 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF3237 PF11578.8 EMC97460.1 - 1.3e-10 41.3 0.0 1.7e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ALAD PF00490.21 EMC97464.1 - 3.5e-120 401.0 0.0 4.2e-120 400.7 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PEP_mutase PF13714.6 EMC97464.1 - 0.16 11.4 1.4 4 6.8 0.0 2.8 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase Ima1_N PF09779.9 EMC97465.1 - 2.8e-32 112.4 5.0 7.2e-32 111.1 5.0 1.7 1 0 0 1 1 1 1 Ima1 N-terminal domain DUF4293 PF14126.6 EMC97465.1 - 0.0027 18.0 0.2 0.0052 17.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) DUF347 PF03988.12 EMC97465.1 - 0.16 12.2 1.5 0.34 11.1 0.5 2.1 1 1 0 1 1 1 0 Repeat of Unknown Function (DUF347) zf-FPG_IleRS PF06827.14 EMC97465.1 - 0.19 11.6 1.8 18 5.3 0.2 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Lar_restr_allev PF14354.6 EMC97465.1 - 1.3 9.4 3.8 1.1 9.7 1.3 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Mito_carr PF00153.27 EMC97466.1 - 2.6e-41 139.4 6.5 6.8e-15 54.8 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2523 PF10734.9 EMC97466.1 - 0.25 12.0 1.0 32 5.2 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2523) IU_nuc_hydro PF01156.19 EMC97468.1 - 2e-13 50.6 0.0 2.4e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SnoaL_4 PF13577.6 EMC97469.1 - 0.00034 20.7 0.0 0.0004 20.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain 4HBT PF03061.22 EMC97471.1 - 2.5e-12 47.0 0.1 3e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EMC97471.1 - 0.0051 17.1 0.0 0.0058 16.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_hydro_127 PF07944.12 EMC97471.1 - 0.093 11.2 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 FAD_binding_3 PF01494.19 EMC97472.1 - 8.9e-16 58.1 0.0 1.6e-15 57.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC97472.1 - 1.7e-07 31.1 0.2 7e-05 22.6 0.2 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC97472.1 - 1.3e-05 24.6 0.4 0.0026 17.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC97472.1 - 0.00024 21.3 0.2 0.00052 20.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC97472.1 - 0.00045 20.7 0.6 0.0015 19.0 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC97472.1 - 0.00047 19.4 0.9 0.00079 18.6 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 EMC97472.1 - 0.00062 19.4 0.2 0.0011 18.6 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EMC97472.1 - 0.0076 15.1 0.1 1.9 7.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EMC97472.1 - 0.022 14.1 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EMC97472.1 - 0.069 13.0 0.3 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.32 EMC97473.1 - 7.7e-12 45.5 8.8 0.01 16.7 0.5 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC97473.1 - 0.0013 19.0 0.1 0.94 9.8 0.0 4.0 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMC97473.1 - 0.11 11.5 0.6 1.6 7.6 0.0 2.7 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3712 PF12505.8 EMC97474.1 - 2.1e-07 31.2 0.1 1.3e-05 25.5 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EMC97474.1 - 0.00029 21.3 4.5 0.013 16.0 0.2 4.8 6 0 0 6 6 6 1 Late embryogenesis abundant protein Mobilization_B PF17511.2 EMC97474.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Mobilization protein B Vac7 PF12751.7 EMC97474.1 - 0.031 13.7 0.0 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 OTCace PF00185.24 EMC97475.1 - 3.9e-45 153.7 0.0 6.4e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EMC97475.1 - 9.3e-44 149.0 0.3 1.6e-43 148.2 0.3 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ACT PF01842.25 EMC97476.1 - 1.2e-14 53.8 0.1 2.1e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 EMC97476.1 - 3e-14 53.0 0.0 2.2e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 EMC97476.1 - 1.9e-08 34.0 0.4 4.1e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 ACT domain KH_1 PF00013.29 EMC97477.1 - 4.9e-10 39.1 0.1 1e-06 28.5 0.0 2.5 2 0 0 2 2 2 2 KH domain T_hemolysin PF12261.8 EMC97477.1 - 0.21 11.3 0.6 0.38 10.5 0.6 1.3 1 0 0 1 1 1 0 Thermostable hemolysin Pkinase PF00069.25 EMC97478.1 - 1.1e-11 44.6 0.0 1.9e-09 37.3 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97478.1 - 1.1e-09 38.0 0.0 7.7e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EMC97478.1 - 0.075 12.9 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family UPF0160 PF03690.13 EMC97479.1 - 9.5e-128 426.3 0.0 1.1e-127 426.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Tyrosinase PF00264.20 EMC97480.1 - 2.1e-52 178.6 0.4 4.8e-52 177.4 0.4 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EMC97480.1 - 1.1e-26 93.9 0.0 2.5e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Tyosinase C-terminal domain Guanylate_kin PF00625.21 EMC97482.1 - 2.5e-64 216.3 0.0 2.8e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EMC97482.1 - 9.4e-08 32.6 0.1 1.9e-07 31.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EMC97482.1 - 2.6e-06 27.7 0.0 2.3e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMC97482.1 - 4.3e-06 27.3 0.0 6.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMC97482.1 - 2.6e-05 24.5 0.0 5.8e-05 23.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EMC97482.1 - 3.5e-05 24.1 0.0 0.0099 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMC97482.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EMC97482.1 - 0.00051 20.6 0.0 0.00085 19.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMC97482.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EMC97482.1 - 0.0034 17.1 0.1 0.0067 16.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 EMC97482.1 - 0.0037 17.2 1.1 0.03 14.3 0.0 2.1 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EMC97482.1 - 0.0042 17.0 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain dNK PF01712.19 EMC97482.1 - 0.005 16.7 0.3 0.062 13.2 0.0 2.2 2 1 0 2 2 2 1 Deoxynucleoside kinase AAA_17 PF13207.6 EMC97482.1 - 0.0056 17.1 0.8 0.14 12.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 EMC97482.1 - 0.0064 16.2 0.3 0.064 13.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMC97482.1 - 0.0077 16.3 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EMC97482.1 - 0.0087 15.7 0.1 0.029 14.0 0.0 1.8 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EMC97482.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EMC97482.1 - 0.02 15.3 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EMC97482.1 - 0.023 15.2 0.3 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EMC97482.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ADK PF00406.22 EMC97482.1 - 0.03 14.4 0.2 0.99 9.5 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase DUF2075 PF09848.9 EMC97482.1 - 0.032 13.5 0.1 0.22 10.7 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EMC97482.1 - 0.033 14.1 0.1 0.086 12.7 0.1 1.9 1 1 0 1 1 1 0 NTPase RNA12 PF10443.9 EMC97482.1 - 0.041 12.6 0.5 0.84 8.3 0.0 2.3 3 0 0 3 3 3 0 RNA12 protein AAA_30 PF13604.6 EMC97482.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMC97482.1 - 0.051 13.5 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EMC97482.1 - 0.057 12.7 0.9 0.32 10.2 0.0 2.2 2 1 0 2 2 2 0 Zeta toxin CPT PF07931.12 EMC97482.1 - 0.067 13.0 0.1 0.35 10.7 0.1 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Thymidylate_kin PF02223.17 EMC97482.1 - 0.067 12.9 0.4 5.5 6.6 0.0 2.5 1 1 1 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 EMC97482.1 - 0.078 12.7 0.4 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_5 PF07728.14 EMC97482.1 - 0.081 12.9 0.2 0.55 10.2 0.0 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EMC97482.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Adeno_IVa2 PF02456.15 EMC97482.1 - 0.15 10.9 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein ATP_bind_1 PF03029.17 EMC97482.1 - 0.15 11.8 0.1 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 EMC97482.1 - 0.16 12.3 0.1 0.6 10.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain PP2C PF00481.21 EMC97483.1 - 2.2e-82 276.5 0.0 2.9e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_like PF01467.26 EMC97484.1 - 1.9e-29 102.7 0.0 4.3e-29 101.5 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 EMC97484.1 - 0.033 14.1 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase Tcp11 PF05794.13 EMC97485.1 - 1.3e-100 337.6 1.9 1.5e-100 337.4 1.9 1.0 1 0 0 1 1 1 1 T-complex protein 11 Spore_YhaL PF14147.6 EMC97485.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL WD40 PF00400.32 EMC97486.1 - 1.2e-32 111.4 11.8 3.2e-07 30.9 0.0 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC97486.1 - 3.2e-09 37.0 0.1 0.0014 18.8 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 EMC97489.1 - 1.2e-18 67.4 0.0 2.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC97489.1 - 2.4e-15 56.8 0.0 6.2e-12 45.8 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EMC97489.1 - 1.9e-10 41.3 0.1 5.2e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 RecQ zinc-binding SNF2_N PF00176.23 EMC97489.1 - 0.02 13.6 0.1 0.03 13.0 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain PPR_2 PF13041.6 EMC97490.1 - 2.8e-14 53.0 0.2 7.2e-05 22.9 0.0 5.0 4 2 1 5 5 5 4 PPR repeat family PPR PF01535.20 EMC97490.1 - 1e-09 37.9 4.1 0.12 12.6 0.0 6.2 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.6 EMC97490.1 - 4.4e-08 33.1 0.1 0.2 11.7 0.0 4.0 3 1 1 4 4 4 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EMC97490.1 - 0.00045 19.6 0.0 0.011 15.1 0.0 2.6 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP ERAP1_C PF11838.8 EMC97490.1 - 0.0016 18.0 0.2 4 6.9 0.0 3.7 3 1 0 4 4 4 1 ERAP1-like C-terminal domain PPR_1 PF12854.7 EMC97490.1 - 0.006 16.3 0.5 17 5.2 0.0 4.0 4 0 0 4 4 4 1 PPR repeat T2SSF PF00482.23 EMC97490.1 - 0.016 15.2 0.2 0.044 13.7 0.2 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F BTAD PF03704.17 EMC97490.1 - 0.018 15.5 0.1 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain RTP1_C2 PF10304.9 EMC97490.1 - 0.36 10.6 3.1 0.8 9.5 0.0 3.0 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 2 MRP-S25 PF13741.6 EMC97491.1 - 9.6e-49 166.0 10.8 1.3e-25 90.4 0.4 3.1 1 1 2 3 3 3 3 Mitochondrial ribosomal protein S25 GRAB PF10375.9 EMC97493.1 - 1.1e-09 37.8 0.1 2.2e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Golgin_A5 PF09787.9 EMC97493.1 - 4.5e-05 23.1 52.1 0.012 15.1 15.7 3.9 1 1 3 4 4 4 4 Golgin subfamily A member 5 Filament PF00038.21 EMC97493.1 - 0.0009 18.9 45.8 0.003 17.2 10.3 3.9 1 1 3 4 4 4 2 Intermediate filament protein FPP PF05911.11 EMC97493.1 - 0.00096 17.5 20.7 0.00096 17.5 20.7 2.4 1 1 1 2 2 2 1 Filament-like plant protein, long coiled-coil HALZ PF02183.18 EMC97493.1 - 0.0013 18.9 0.4 0.0013 18.9 0.4 4.2 5 0 0 5 5 2 2 Homeobox associated leucine zipper Spc7 PF08317.11 EMC97493.1 - 0.0023 16.9 19.6 0.0023 16.9 19.6 3.2 1 1 2 3 3 3 1 Spc7 kinetochore protein BST2 PF16716.5 EMC97493.1 - 0.0062 17.1 42.0 0.4 11.3 11.2 5.5 2 2 3 5 5 5 2 Bone marrow stromal antigen 2 Phage_GP20 PF06810.11 EMC97493.1 - 0.013 15.3 36.7 0.29 10.9 4.8 4.0 2 2 1 3 3 3 0 Phage minor structural protein GP20 DUF1664 PF07889.12 EMC97493.1 - 0.084 12.9 26.3 0.77 9.8 1.1 4.3 2 2 4 6 6 6 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EMC97493.1 - 0.089 13.3 16.7 2.1 8.8 0.3 4.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 EMC97493.1 - 0.097 10.2 51.7 0.53 7.7 22.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 EMC97493.1 - 0.13 12.3 29.3 0.17 11.9 6.4 3.3 2 1 1 3 3 3 0 Laminin Domain II TPR_MLP1_2 PF07926.12 EMC97493.1 - 0.19 11.8 56.8 6.6 6.8 5.9 4.5 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 EMC97493.1 - 0.36 11.2 28.9 0.28 11.5 7.3 4.5 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 EMC97493.1 - 0.37 10.8 54.8 1.8 8.6 17.3 3.8 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoO PF09769.9 EMC97493.1 - 0.45 10.5 12.1 13 5.7 0.8 4.4 2 2 3 5 5 5 0 Apolipoprotein O Tweety PF04906.13 EMC97493.1 - 1.4 7.5 11.2 0.32 9.6 1.9 2.6 2 1 0 2 2 2 0 Tweety IFT57 PF10498.9 EMC97493.1 - 1.5 7.8 41.0 1.2 8.0 13.3 3.9 1 1 3 4 4 4 0 Intra-flagellar transport protein 57 ATG16 PF08614.11 EMC97493.1 - 1.6 8.9 63.2 2.1 8.5 9.5 4.1 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 EMC97493.1 - 2.5 8.1 49.3 7.3 6.6 12.5 3.4 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4795 PF16043.5 EMC97493.1 - 2.8 7.5 37.0 0.4 10.2 23.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF2316 PF10078.9 EMC97493.1 - 2.9 8.2 8.6 3.1 8.1 0.8 3.1 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2316) ADIP PF11559.8 EMC97493.1 - 4 7.5 50.3 3.1 7.9 14.7 3.9 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Prefoldin PF02996.17 EMC97493.1 - 4 7.4 32.1 4.8 7.1 6.1 5.4 2 2 3 5 5 5 0 Prefoldin subunit Lebercilin PF15619.6 EMC97493.1 - 4.5 6.9 53.8 0.058 13.0 14.3 3.7 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease KxDL PF10241.9 EMC97493.1 - 4.7 7.5 27.9 2.3 8.5 1.1 3.9 2 2 1 3 3 3 0 Uncharacterized conserved protein DUF4618 PF15397.6 EMC97493.1 - 4.8 6.5 35.7 0.18 11.2 12.6 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) Prp19 PF08606.11 EMC97493.1 - 5 7.2 10.0 3.7 7.6 0.3 3.7 3 1 0 3 3 3 0 Prp19/Pso4-like COG5 PF10392.9 EMC97493.1 - 5.6 7.2 25.8 0.75 10.0 5.9 3.8 2 2 2 4 4 4 0 Golgi transport complex subunit 5 FlaC_arch PF05377.11 EMC97493.1 - 5.7 7.4 22.3 18 5.8 0.1 5.5 2 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 EMC97493.1 - 9 6.6 29.7 0.053 13.8 15.0 2.9 2 1 0 2 2 1 0 Domain of unknown function (DUF5082) WD40 PF00400.32 EMC97495.1 - 4.3e-23 81.2 14.6 3.3e-06 27.7 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC97495.1 - 1.1e-07 32.0 1.1 0.65 10.3 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC97495.1 - 1.6e-06 27.1 4.2 0.065 11.9 0.1 3.8 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EMC97495.1 - 4.4e-06 25.9 0.1 0.29 10.1 0.0 3.4 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EMC97495.1 - 0.037 12.9 0.1 0.037 12.9 0.1 2.3 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EMC97495.1 - 0.086 11.1 0.0 0.21 9.9 0.0 1.6 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ribosomal_L31e PF01198.19 EMC97496.1 - 7.4e-17 61.4 0.1 9.5e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e PP2C PF00481.21 EMC97497.1 - 1.3e-39 136.4 0.0 2.3e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EMC97497.1 - 0.063 13.2 0.1 5.3 6.9 0.0 2.9 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) DUF4064 PF13273.6 EMC97498.1 - 1.3 9.3 9.2 1.1 9.6 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Clc-like PF07062.12 EMC97498.1 - 8.3 5.8 11.5 1.1 8.7 0.2 2.6 1 1 2 3 3 3 0 Clc-like PNK3P PF08645.11 EMC97501.1 - 2.2e-55 186.8 0.0 4.1e-55 185.9 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EMC97501.1 - 2.8e-25 89.1 0.1 2e-22 79.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain HAD_2 PF13419.6 EMC97501.1 - 0.012 15.7 0.3 1.1 9.4 0.0 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase KTI12 PF08433.10 EMC97501.1 - 0.014 14.9 0.3 2.5 7.5 0.0 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 EMC97501.1 - 0.046 13.4 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hydrolase_like PF13242.6 EMC97501.1 - 0.068 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like RsgA_GTPase PF03193.16 EMC97501.1 - 0.098 12.6 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EMC97501.1 - 0.15 12.4 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SUR7 PF06687.12 EMC97502.1 - 2.4e-39 135.2 20.1 2.9e-39 134.9 20.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Bacillus_PapR PF05968.11 EMC97502.1 - 0.3 11.0 2.9 0.93 9.4 0.9 2.3 2 0 0 2 2 2 0 Bacillus PapR protein DUF3671 PF12420.8 EMC97502.1 - 1 9.4 7.4 10 6.2 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function SCIMP PF15050.6 EMC97502.1 - 1.4 9.4 4.0 12 6.3 0.2 2.4 1 1 1 2 2 2 0 SCIMP protein Fig1 PF12351.8 EMC97502.1 - 9.1 6.2 15.0 5.1 7.0 11.8 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF1712 PF08217.11 EMC97504.1 - 5.7e-18 64.7 0.0 2.1e-15 56.3 0.0 2.6 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) ABC2_membrane PF01061.24 EMC97505.1 - 1.6e-90 302.1 57.6 6.1e-50 169.6 25.5 2.8 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EMC97505.1 - 1.3e-36 126.1 0.0 2.4e-17 63.7 0.0 3.5 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EMC97505.1 - 1.3e-32 111.6 2.9 9.3e-31 105.6 0.1 3.9 5 0 0 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EMC97505.1 - 1.8e-15 57.3 2.4 9.6e-15 55.0 2.4 2.3 1 1 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 EMC97505.1 - 9.7e-08 32.3 0.2 0.0014 18.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EMC97505.1 - 5.9e-06 26.3 0.1 0.00026 20.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EMC97505.1 - 1.8e-05 24.4 0.0 0.00016 21.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMC97505.1 - 2.2e-05 24.9 0.1 0.0052 17.2 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EMC97505.1 - 9.7e-05 22.9 0.0 0.008 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EMC97505.1 - 0.00033 21.1 0.4 0.034 14.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMC97505.1 - 0.00065 19.4 1.9 0.032 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EMC97505.1 - 0.0012 18.5 0.3 0.31 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EMC97505.1 - 0.0029 17.5 0.0 2 8.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMC97505.1 - 0.0034 16.8 0.0 0.54 9.7 0.0 3.4 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMC97505.1 - 0.012 15.8 0.1 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EMC97505.1 - 0.023 14.3 0.8 0.54 9.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EMC97505.1 - 0.05 13.5 0.5 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EMC97505.1 - 0.17 11.6 0.1 19 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain GARS_A PF01071.19 EMC97506.1 - 2.2e-84 282.1 0.0 2.9e-84 281.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EMC97506.1 - 3.7e-33 114.2 0.0 6.6e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EMC97506.1 - 1.8e-28 98.6 0.5 4.5e-28 97.4 0.5 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 EMC97506.1 - 1.3e-05 24.8 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EMC97506.1 - 2.5e-05 24.4 0.0 5.2e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EMC97506.1 - 0.00034 20.2 0.0 0.00057 19.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EMC97506.1 - 0.00091 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EMC97506.1 - 0.041 13.5 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 EMC97506.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EMC97506.1 - 0.2 11.4 0.0 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon MINDY_DUB PF04424.13 EMC97507.1 - 1.7e-28 99.0 0.0 3.1e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase PIG-X PF08320.12 EMC97508.1 - 1.1e-68 231.3 0.0 1.7e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Fcf2 PF08698.11 EMC97509.1 - 2.3e-36 124.1 3.2 3.5e-36 123.5 0.1 2.6 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.20 EMC97510.1 - 3.5e-53 180.3 0.1 4.5e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.22 EMC97511.1 - 5.6e-24 84.2 0.0 1.1e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Folliculin_C PF16692.5 EMC97511.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Folliculin C-terminal domain Aconitase PF00330.20 EMC97512.1 - 1.6e-143 479.1 0.0 2e-143 478.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMC97512.1 - 2.1e-39 134.8 0.0 3.2e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Endosulfine PF04667.17 EMC97513.1 - 7.3e-31 106.1 0.9 1.1e-30 105.5 0.6 1.5 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.13 EMC97514.1 - 1.6e-74 249.8 0.0 1.9e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase PRK PF00485.18 EMC97515.1 - 2.5e-07 30.6 0.0 4.5e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EMC97515.1 - 2.1e-06 27.2 0.0 3.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 EMC97515.1 - 5.7e-05 23.3 0.6 0.00072 19.7 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMC97515.1 - 6.6e-05 23.4 0.0 8.6e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EMC97515.1 - 0.00035 21.1 0.0 0.0083 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EMC97515.1 - 0.00059 19.2 0.1 0.004 16.4 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.6 EMC97515.1 - 0.00085 19.8 0.1 0.032 14.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EMC97515.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EMC97515.1 - 0.0016 18.9 0.0 0.005 17.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 EMC97515.1 - 0.0019 17.9 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase NACHT PF05729.12 EMC97515.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 EMC97515.1 - 0.0029 17.9 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMC97515.1 - 0.0038 17.0 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 EMC97515.1 - 0.006 15.7 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EMC97515.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EMC97515.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 EMC97515.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 EMC97515.1 - 0.024 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 EMC97515.1 - 0.032 14.1 0.1 0.075 12.9 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase MeaB PF03308.16 EMC97515.1 - 0.04 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EMC97515.1 - 0.042 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SKI PF01202.22 EMC97515.1 - 0.045 13.9 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_24 PF13479.6 EMC97515.1 - 0.047 13.4 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EMC97515.1 - 0.058 13.0 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EMC97515.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EMC97515.1 - 0.066 13.5 0.1 0.098 13.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EMC97515.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EMC97515.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EMC97515.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 EMC97515.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EMC97515.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EMC97515.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EMC97515.1 - 0.2 12.1 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF1761 PF08570.10 EMC97516.1 - 4.1e-28 98.1 4.2 4.7e-28 97.9 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) zf_Hakai PF18408.1 EMC97517.1 - 0.015 15.0 1.4 2.9 7.7 0.0 2.6 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain HATPase_c_3 PF13589.6 EMC97518.1 - 4.3e-13 49.3 0.0 9.1e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EMC97518.1 - 5.9e-06 26.1 0.0 0.00028 20.7 0.0 3.1 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 EMC97518.1 - 7.2e-05 23.3 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase bZIP_1 PF00170.21 EMC97520.1 - 5.9e-05 23.1 13.2 9e-05 22.5 13.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor HMMR_N PF15905.5 EMC97520.1 - 0.0057 16.2 1.0 0.0077 15.7 1.0 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal bZIP_2 PF07716.15 EMC97520.1 - 0.025 14.7 13.6 0.033 14.2 13.6 1.2 1 0 0 1 1 1 0 Basic region leucine zipper DUF4407 PF14362.6 EMC97520.1 - 0.082 12.2 2.0 0.11 11.8 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_S20p PF01649.18 EMC97520.1 - 0.66 10.7 6.9 0.35 11.5 4.9 1.5 2 0 0 2 2 2 0 Ribosomal protein S20 DivIC PF04977.15 EMC97520.1 - 2.4 8.0 5.5 6.2 6.7 5.5 1.7 1 1 0 1 1 1 0 Septum formation initiator Kin17_mid PF10357.9 EMC97521.1 - 7.7e-51 171.3 0.1 1.3e-50 170.5 0.1 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 EMC97521.1 - 7.5e-05 22.9 1.5 0.00017 21.8 1.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC97521.1 - 0.0025 18.1 1.8 0.0045 17.3 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EMC97521.1 - 0.0038 17.5 2.7 0.017 15.4 0.4 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF5105 PF17118.5 EMC97521.1 - 0.069 12.9 0.9 0.09 12.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5105) MFS_1 PF07690.16 EMC97522.1 - 1.6e-33 116.1 29.0 5.8e-32 111.0 29.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EMC97523.1 - 1.5e-40 139.2 56.3 1.5e-40 139.2 56.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC97523.1 - 1.6e-11 43.3 29.4 3.1e-11 42.4 29.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMC97523.1 - 9.7e-10 37.9 18.0 9.7e-10 37.9 18.0 3.4 3 1 1 4 4 4 1 Sugar (and other) transporter ThylakoidFormat PF11264.8 EMC97523.1 - 0.25 11.0 0.1 0.4 10.3 0.1 1.2 1 0 0 1 1 1 0 Thylakoid formation protein SARAF PF06682.12 EMC97524.1 - 6.8e-99 331.7 0.1 8.4e-99 331.3 0.1 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Defb50 PF17546.2 EMC97524.1 - 0.03 14.2 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Beta defensin 50 DUF4538 PF15061.6 EMC97524.1 - 0.21 11.3 0.1 0.38 10.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) NDUF_B12 PF08122.12 EMC97524.1 - 0.43 10.7 2.3 4.9 7.3 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family tRNA-synt_2b PF00587.25 EMC97525.1 - 5.2e-37 127.5 0.1 1.7e-36 125.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EMC97525.1 - 8.1e-15 55.0 6.1 8.1e-15 55.0 6.1 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain PIN_12 PF16289.5 EMC97525.1 - 0.16 12.5 5.7 0.28 11.7 4.3 2.0 2 0 0 2 2 2 0 PIN domain ICE2 PF08426.10 EMC97526.1 - 9.5e-153 509.1 2.9 1.1e-152 508.9 2.9 1.0 1 0 0 1 1 1 1 ICE2 adh_short_C2 PF13561.6 EMC97527.1 - 3.2e-37 128.3 0.0 4.8e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC97527.1 - 1.7e-35 122.2 0.0 2.6e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC97527.1 - 3.6e-09 36.8 2.0 6.4e-08 32.7 2.0 2.2 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EMC97527.1 - 0.036 14.0 0.1 0.087 12.8 0.1 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 EMC97527.1 - 0.1 12.0 0.1 0.46 9.9 0.0 2.0 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMC97527.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pkinase PF00069.25 EMC97528.1 - 6.1e-72 242.2 0.0 2e-71 240.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97528.1 - 8.5e-50 169.4 0.0 1.5e-49 168.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMC97528.1 - 0.0062 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMC97528.1 - 0.0097 15.2 0.0 0.062 12.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like KAP PF05804.12 EMC97528.1 - 0.014 13.6 2.0 0.028 12.6 2.0 1.4 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) NUDIX_4 PF14815.6 EMC97528.1 - 0.03 14.3 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 NUDIX domain Arm PF00514.23 EMC97528.1 - 0.096 12.8 3.0 26 5.0 0.0 5.1 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat DUF4704 PF15787.5 EMC97528.1 - 0.35 10.1 9.8 0.54 9.4 0.3 3.0 3 1 0 4 4 4 0 Domain of unknown function (DUF4704) DnaJ PF00226.31 EMC97530.1 - 1.7e-19 69.7 0.4 2.8e-19 69.0 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain AIM5 PF17050.5 EMC97535.1 - 1e-16 61.5 1.7 3.2e-16 59.9 1.7 1.9 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 LEA_4 PF02987.16 EMC97535.1 - 0.00036 20.5 0.8 1.4 9.1 1.2 2.6 2 0 0 2 2 2 2 Late embryogenesis abundant protein Synuclein PF01387.17 EMC97535.1 - 0.00099 19.3 31.3 0.14 12.4 8.3 3.4 1 1 2 3 3 3 3 Synuclein Apolipoprotein PF01442.18 EMC97535.1 - 0.011 15.6 34.0 0.14 12.0 25.8 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Phage_Gp111 PF07410.11 EMC97535.1 - 0.98 9.9 6.4 29 5.2 0.0 3.3 1 1 1 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein DUF5598 PF18127.1 EMC97535.1 - 1.4 9.4 3.1 21 5.6 0.1 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF5598) ATG_C PF09333.11 EMC97535.1 - 3.3 8.1 14.5 7.2 7.0 0.3 4.0 1 1 2 3 3 3 0 Autophagy-related protein C terminal domain Phi_1 PF04674.12 EMC97535.1 - 7.4 5.8 8.9 5.3 6.3 2.1 2.8 1 1 1 3 3 3 0 Phosphate-induced protein 1 conserved region Ribosomal_L17 PF01196.19 EMC97536.1 - 2e-34 118.3 0.4 3.9e-34 117.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 Mrpl_C PF18502.1 EMC97536.1 - 0.0016 18.7 0.2 0.05 13.9 0.0 2.2 2 0 0 2 2 2 1 54S ribosomal protein L8 C-terminal domain DUF1719 PF08224.11 EMC97536.1 - 0.096 11.8 0.4 0.26 10.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1719) zf-RING_2 PF13639.6 EMC97538.1 - 2.1e-07 31.2 4.4 2.1e-07 31.2 4.4 3.1 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMC97538.1 - 5.9e-05 22.8 13.1 0.00016 21.4 3.3 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMC97538.1 - 0.0021 18.3 6.2 0.0086 16.3 6.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EMC97538.1 - 0.0041 16.8 1.3 0.014 15.1 1.3 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EMC97538.1 - 0.58 10.1 21.8 0.057 13.3 2.4 3.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC97538.1 - 3.7 7.5 20.9 0.31 10.9 2.4 4.2 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 SANT_DAMP1_like PF16282.5 EMC97539.1 - 3.3e-25 88.1 1.4 6.3e-25 87.2 1.4 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EMC97539.1 - 0.0067 16.3 0.0 0.43 10.4 0.0 2.3 2 0 0 2 2 2 2 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 EMC97539.1 - 0.011 15.9 0.5 0.049 13.9 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain COesterase PF00135.28 EMC97540.1 - 4e-83 280.0 0.8 4.7e-83 279.8 0.8 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC97540.1 - 3.3e-06 27.1 0.4 2.3e-05 24.4 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipoprotein_21 PF14041.6 EMC97540.1 - 0.1 12.8 0.3 0.6 10.3 0.0 2.4 3 0 0 3 3 3 0 LppP/LprE lipoprotein DUF3237 PF11578.8 EMC97541.1 - 1.2e-49 168.0 0.0 1.4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) NAD_binding_8 PF13450.6 EMC97542.1 - 1.2e-13 51.0 0.2 3.2e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC97542.1 - 8e-09 35.1 0.5 1.7e-05 24.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC97542.1 - 3.8e-08 33.3 2.7 5.6e-06 26.2 0.1 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EMC97542.1 - 1.2e-07 31.5 0.0 0.00016 21.1 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EMC97542.1 - 5.7e-06 26.8 0.7 0.17 12.5 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC97542.1 - 7.9e-06 24.8 0.4 0.0032 16.3 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 EMC97542.1 - 1e-05 25.6 0.0 0.00024 21.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EMC97542.1 - 1.3e-05 24.5 0.2 2.1e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMC97542.1 - 7.3e-05 22.1 0.1 0.002 17.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EMC97542.1 - 0.0055 15.8 0.1 0.0086 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Shikimate_DH PF01488.20 EMC97542.1 - 0.023 14.8 0.1 0.048 13.7 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 EMC97542.1 - 0.023 13.9 0.1 0.15 11.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EMC97542.1 - 0.033 14.6 0.6 0.34 11.4 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EMC97542.1 - 0.085 12.1 0.0 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 EMC97542.1 - 0.13 12.6 0.1 0.39 11.0 0.0 1.9 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 EMC97542.1 - 0.21 10.9 0.7 0.51 9.7 0.0 1.9 2 1 0 2 2 2 0 ThiF family Ank_2 PF12796.7 EMC97543.1 - 7.9e-26 90.5 1.6 2.7e-12 47.1 0.5 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC97543.1 - 8.7e-22 77.2 4.8 4.3e-10 39.9 0.1 5.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) SPX PF03105.19 EMC97543.1 - 1.6e-21 77.7 16.7 3.7e-09 37.0 0.7 3.2 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 EMC97543.1 - 5.7e-13 48.8 2.6 0.0068 16.7 0.1 5.7 3 1 3 6 6 6 3 Ankyrin repeats (many copies) GDPD PF03009.17 EMC97543.1 - 9.8e-12 45.1 0.0 6.4e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_3 PF13606.6 EMC97543.1 - 2.7e-10 39.6 6.4 0.0086 16.5 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 EMC97543.1 - 4.3e-08 33.2 6.3 0.0025 18.2 0.0 5.9 7 0 0 7 7 7 2 Ankyrin repeat SH3_19 PF18597.1 EMC97543.1 - 0.11 12.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain He_PIG PF05345.12 EMC97544.1 - 2.5e-18 66.0 14.3 2.5e-06 27.6 1.3 4.7 4 0 0 4 4 4 3 Putative Ig domain DUF3042 PF11240.8 EMC97544.1 - 3.4 7.8 4.2 34 4.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) Methyltransf_16 PF10294.9 EMC97545.1 - 1.4e-29 103.0 0.0 6e-28 97.7 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Coa1 PF08695.10 EMC97548.1 - 8.9e-40 135.1 0.0 1.1e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2431 PF10354.9 EMC97549.1 - 5.6e-69 231.7 0.0 6.9e-69 231.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Sedlin_N PF04628.13 EMC97550.1 - 7.3e-16 58.5 0.0 1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Oxidored_q6 PF01058.22 EMC97551.1 - 1.2e-21 76.9 0.0 1.7e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mt_ATP-synt_D PF05873.12 EMC97552.1 - 0.038 13.9 4.9 0.35 10.7 0.1 2.5 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) zf-C2H2_aberr PF17017.5 EMC97552.1 - 0.044 13.9 1.3 0.071 13.3 0.6 1.6 2 0 0 2 2 2 0 Aberrant zinc-finger Glyco_hydro_92 PF07971.12 EMC97554.1 - 1.1e-145 486.1 0.0 1.3e-145 485.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMC97554.1 - 8.7e-69 232.0 0.9 1.3e-68 231.4 0.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain TPR_12 PF13424.6 EMC97554.1 - 0.21 11.9 0.1 0.41 11.0 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Steroid_dh PF02544.16 EMC97557.1 - 1.6e-15 57.4 0.3 2.7e-14 53.4 0.3 2.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Fungal_trans PF04082.18 EMC97558.1 - 6e-21 74.7 0.2 1.9e-20 73.0 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC97558.1 - 8.4e-05 22.6 18.2 0.00022 21.3 18.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACOX PF01756.19 EMC97558.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Acyl-CoA oxidase DHquinase_I PF01487.15 EMC97559.1 - 2.5e-45 155.5 0.0 4.5e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase His_Phos_2 PF00328.22 EMC97560.1 - 2.1e-22 80.0 0.0 3.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 EMC97562.1 - 3.7e-10 39.6 0.0 6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 EMC97562.1 - 1.5e-07 31.1 0.5 0.11 12.8 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Pkinase_Tyr PF07714.17 EMC97562.1 - 1.9e-07 30.6 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 EMC97562.1 - 3.1e-07 30.6 0.0 3.6e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EMC97562.1 - 8.2e-05 23.0 0.2 0.46 11.1 0.1 3.7 4 0 0 4 4 4 2 HEAT-like repeat Kinase-like PF14531.6 EMC97562.1 - 0.0001 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 EMC97562.1 - 0.00023 21.5 0.3 0.0062 16.9 0.2 2.8 1 1 2 3 3 3 2 HEAT repeats Forkhead PF00250.18 EMC97564.1 - 0.00021 21.5 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain DUF4769 PF15992.5 EMC97564.1 - 7.2 6.3 5.6 3.9 7.2 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) Ion_trans PF00520.31 EMC97565.1 - 4.6e-10 39.1 0.5 5.6e-10 38.9 0.5 1.1 1 0 0 1 1 1 1 Ion transport protein DUF5608 PF18356.1 EMC97565.1 - 0.17 11.9 1.2 6.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5608) PKD_channel PF08016.12 EMC97565.1 - 0.18 10.5 3.1 0.14 10.8 2.0 1.3 1 1 0 1 1 1 0 Polycystin cation channel KOW PF00467.29 EMC97566.1 - 0.024 14.6 2.1 0.071 13.1 2.1 1.9 1 0 0 1 1 1 0 KOW motif DUF5641 PF18701.1 EMC97566.1 - 0.15 12.3 0.6 1 9.6 0.6 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5641) Hist_deacetyl PF00850.19 EMC97566.1 - 0.22 11.0 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylase domain Y_phosphatase2 PF03162.13 EMC97567.1 - 8.2e-41 139.3 0.0 8.9e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EMC97567.1 - 3.1e-07 30.6 0.0 1.3e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EMC97567.1 - 0.0089 15.8 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMC97567.1 - 0.039 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ras PF00071.22 EMC97568.1 - 2.1e-55 186.7 0.0 2.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC97568.1 - 7.1e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC97568.1 - 9.9e-07 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EMC97568.1 - 0.0024 17.3 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 EMC97568.1 - 0.037 13.2 0.1 0.5 9.5 0.0 2.0 1 1 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 EMC97568.1 - 0.038 13.7 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EMC97568.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DSPc PF00782.20 EMC97569.1 - 8.8e-26 90.3 0.0 1.2e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EMC97569.1 - 0.0027 18.0 0.0 0.005 17.1 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Yippee-Mis18 PF03226.14 EMC97569.1 - 0.0042 17.3 1.0 0.0091 16.2 1.0 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Y_phosphatase3 PF13350.6 EMC97569.1 - 0.077 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 EMC97569.1 - 0.081 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-RING_5 PF14634.6 EMC97569.1 - 0.18 11.8 5.1 1.7 8.7 5.0 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_4 PF13717.6 EMC97569.1 - 0.23 11.4 2.1 28 4.7 0.3 3.1 2 0 0 2 2 2 0 zinc-ribbon domain Terminase_GpA PF05876.12 EMC97569.1 - 0.37 9.3 4.5 0.73 8.3 4.5 1.5 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) HypA PF01155.19 EMC97569.1 - 0.55 10.3 3.5 1.9 8.5 0.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2 PF00096.26 EMC97570.1 - 0.022 15.2 0.8 0.022 15.2 0.8 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC97570.1 - 0.061 13.8 0.3 0.061 13.8 0.3 3.8 4 1 0 4 4 4 0 Zinc-finger double domain PyrI_C PF02748.15 EMC97570.1 - 0.07 13.1 0.2 13 5.8 0.5 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.9 EMC97570.1 - 0.084 12.9 2.7 3 8.0 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_4 PF13894.6 EMC97570.1 - 6.3 7.9 23.0 1.9 9.5 1.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger Lyase_1 PF00206.20 EMC97571.1 - 3.8e-96 322.2 0.0 5.4e-96 321.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EMC97571.1 - 1.2e-23 83.6 0.0 3e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DPBB_1 PF03330.18 EMC97572.1 - 0.0025 18.0 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EMC97572.1 - 0.059 13.2 0.3 0.066 13.1 0.3 1.3 1 1 0 1 1 1 0 Barwin family SKG6 PF08693.10 EMC97573.1 - 5.9e-08 32.0 0.7 5.9e-08 32.0 0.7 2.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EMC97573.1 - 0.00077 19.3 0.3 0.0011 18.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EMC97573.1 - 0.0025 17.7 4.9 0.024 14.5 4.9 2.5 1 1 0 1 1 1 1 TMEM154 protein family DUF4328 PF14219.6 EMC97573.1 - 0.033 13.8 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF4381 PF14316.6 EMC97573.1 - 0.06 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SCF PF02404.15 EMC97573.1 - 0.094 12.0 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Stem cell factor Stevor PF17410.2 EMC97573.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.8 1 1 0 2 2 2 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 EMC97573.1 - 0.13 13.2 0.0 0.24 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.6 EMC97573.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A CD34_antigen PF06365.12 EMC97573.1 - 0.23 11.0 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family adh_short_C2 PF13561.6 EMC97574.1 - 3e-36 125.2 0.8 7.2e-36 123.9 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC97574.1 - 4.4e-30 104.6 0.0 3.8e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_deac_1 PF01522.21 EMC97574.1 - 1.3e-16 60.7 0.0 5.1e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMC97574.1 - 5.1e-06 26.3 0.0 1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Epimerase PF01370.21 EMC97574.1 - 0.00035 20.1 0.0 0.00081 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMC97574.1 - 0.00042 20.3 0.2 0.009 15.9 0.2 2.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EMC97574.1 - 0.0015 18.4 0.1 0.0037 17.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EMC97574.1 - 0.011 14.7 0.0 0.021 13.9 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family XdhC_CoxI PF02625.16 EMC97574.1 - 0.056 13.6 0.9 0.16 12.2 0.9 1.8 1 0 0 1 1 1 0 XdhC and CoxI family Aminotran_3 PF00202.21 EMC97575.1 - 1.6e-43 148.9 0.2 1.1e-41 142.9 0.2 2.0 1 1 0 1 1 1 1 Aminotransferase class-III MmgE_PrpD PF03972.14 EMC97576.1 - 1.6e-97 326.8 14.5 6.5e-73 245.7 12.0 2.0 1 1 1 2 2 2 2 MmgE/PrpD family Ago_N_1 PF18351.1 EMC97577.1 - 0.039 14.4 0.1 0.56 10.7 0.0 2.2 2 0 0 2 2 2 0 Fungal Argonaute N-terminal domain Ribosomal_L34 PF00468.17 EMC97577.1 - 0.41 10.6 0.1 0.41 10.6 0.1 2.4 3 0 0 3 3 3 0 Ribosomal protein L34 PKcGMP_CC PF16808.5 EMC97578.1 - 5.6 6.9 9.8 7 6.6 1.6 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MHYT PF03707.16 EMC97581.1 - 6.1e-16 58.3 20.5 5.7e-08 32.8 0.2 5.1 4 1 0 4 4 4 3 Bacterial signalling protein N terminal repeat EamA PF00892.20 EMC97582.1 - 8.1e-20 71.4 27.1 4.5e-10 39.8 12.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family Sugar_tr PF00083.24 EMC97584.1 - 3.3e-84 283.3 13.8 3.7e-84 283.2 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC97584.1 - 1e-09 37.8 40.3 1.9e-07 30.3 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0715 PF17094.5 EMC97584.1 - 0.0025 18.4 2.9 0.0025 18.4 2.9 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0715) DUF2953 PF11167.8 EMC97584.1 - 2.5 8.2 5.7 5 7.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) Aminotran_1_2 PF00155.21 EMC97585.1 - 1.7e-45 155.7 0.0 2.1e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EMC97585.1 - 0.00034 20.0 0.0 0.00051 19.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Sugar_tr PF00083.24 EMC97586.1 - 7.7e-101 338.2 26.4 1.1e-99 334.3 26.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC97586.1 - 3.9e-17 62.2 36.0 4.6e-17 62.0 27.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMC97586.1 - 3.6e-05 22.5 24.5 0.00058 18.5 4.0 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein Peroxin-3 PF04882.12 EMC97587.1 - 1.9e-157 525.1 0.1 2.2e-157 524.8 0.1 1.0 1 0 0 1 1 1 1 Peroxin-3 Glyco_transf_22 PF03901.17 EMC97588.1 - 6.6e-56 190.3 17.4 8.4e-56 190.0 17.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3291 PF11695.8 EMC97588.1 - 0.16 11.7 0.7 0.3 10.8 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) Aldo_ket_red PF00248.21 EMC97591.1 - 2.5e-46 158.2 0.0 1.1e-45 156.1 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family ALG11_N PF15924.5 EMC97593.1 - 1.7e-81 273.2 0.0 2.6e-81 272.7 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EMC97593.1 - 1.6e-19 70.1 0.0 2.6e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EMC97593.1 - 3e-10 40.6 0.0 5.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMC97593.1 - 0.02 14.9 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Eno-Rase_FAD_bd PF07055.12 EMC97593.1 - 0.19 12.2 0.1 0.65 10.5 0.0 2.0 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain 60KD_IMP PF02096.20 EMC97594.1 - 0.00049 20.1 0.3 0.0011 18.9 0.0 1.8 2 1 0 2 2 2 1 60Kd inner membrane protein Aim19 PF10315.9 EMC97595.1 - 1.1e-05 25.6 0.1 1.7e-05 25.0 0.1 1.3 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 EMC97596.1 - 5.1e-28 97.4 0.0 1e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EMC97596.1 - 6e-21 74.3 0.3 9.1e-21 73.8 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF974 PF06159.13 EMC97597.1 - 3.1e-74 249.9 0.0 3.7e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF2408 PF10303.9 EMC97598.1 - 2.3e-48 164.2 12.1 1.6e-29 103.2 1.8 5.1 4 2 1 5 5 5 4 Protein of unknown function (DUF2408) Cob_adeno_trans PF01923.18 EMC97598.1 - 0.0023 18.1 1.3 0.74 9.9 0.0 3.2 3 1 1 4 4 4 2 Cobalamin adenosyltransferase ATG16 PF08614.11 EMC97598.1 - 0.1 12.8 6.1 0.79 9.9 0.4 3.5 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) DUF3368 PF11848.8 EMC97598.1 - 0.13 12.0 0.0 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) FAM167 PF11652.8 EMC97598.1 - 0.26 11.8 3.6 17 6.0 0.2 3.6 3 0 0 3 3 3 0 FAM167 Snapin_Pallidin PF14712.6 EMC97598.1 - 1.4 9.4 7.8 0.68 10.4 1.4 3.4 4 0 0 4 4 4 0 Snapin/Pallidin Spore_III_AB PF09548.10 EMC97598.1 - 2.8 8.0 5.5 0.35 11.0 0.3 2.1 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) TMF_TATA_bd PF12325.8 EMC97598.1 - 3.8 7.8 10.3 0.15 12.3 2.4 2.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Ribosomal_60s PF00428.19 EMC97599.1 - 5.8e-22 78.1 22.7 9e-21 74.3 22.7 2.0 1 1 0 1 1 1 1 60s Acidic ribosomal protein Phage_holin_6_1 PF09682.10 EMC97599.1 - 0.071 13.5 2.6 2.6 8.5 0.2 2.1 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) SOG2 PF10428.9 EMC97600.1 - 4.8e-36 125.0 25.2 1.9e-21 76.9 9.4 3.1 2 1 1 3 3 3 2 RAM signalling pathway protein LRR_8 PF13855.6 EMC97600.1 - 4e-12 45.7 3.0 3.7e-05 23.4 0.1 2.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EMC97600.1 - 1.9e-09 37.6 1.2 0.00082 19.7 0.1 3.8 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EMC97600.1 - 0.0033 16.9 0.1 0.0085 15.6 0.0 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 EMC97600.1 - 0.0066 16.8 0.6 4.4 8.2 0.1 3.5 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_6 PF13516.6 EMC97600.1 - 0.0074 16.3 0.6 17 5.8 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeat BPL_LplA_LipB PF03099.19 EMC97601.1 - 0.0019 18.1 0.0 0.013 15.4 0.0 2.1 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BLOC1_2 PF10046.9 EMC97602.1 - 0.021 15.1 0.5 3.8 7.9 0.1 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec34 PF04136.15 EMC97602.1 - 0.088 12.7 0.7 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Sec34-like family Mur_ligase_M PF08245.12 EMC97603.1 - 0.0061 16.6 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Mur ligase middle domain Lactonase PF10282.9 EMC97605.1 - 4.5e-05 22.9 0.1 1.6 7.9 0.0 3.6 3 1 1 4 4 4 3 Lactonase, 7-bladed beta-propeller Metallophos_2 PF12850.7 EMC97606.1 - 1.6e-10 41.4 0.0 2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 EMC97607.1 - 2.7e-31 108.9 0.0 3.4e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMC97607.1 - 0.00068 18.3 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 EMC97607.1 - 0.036 14.1 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain ILVD_EDD PF00920.21 EMC97608.1 - 1.1e-151 506.0 0.3 1.2e-151 505.8 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family FAD_binding_3 PF01494.19 EMC97609.1 - 0.03 13.6 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_3 PF07859.13 EMC97610.1 - 6.5e-47 160.1 0.0 9.5e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC97610.1 - 0.00014 20.9 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF3025 PF11227.8 EMC97610.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3025) Abhydro_lipase PF04083.16 EMC97610.1 - 0.044 13.4 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Esterase_phd PF10503.9 EMC97610.1 - 0.062 12.8 1.1 0.63 9.5 0.4 2.4 2 1 0 2 2 2 0 Esterase PHB depolymerase ABC2_membrane PF01061.24 EMC97612.1 - 3.8e-23 82.0 17.9 6.2e-23 81.3 17.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EMC97612.1 - 1.3e-11 45.1 0.0 2.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EMC97612.1 - 3.6e-05 24.2 0.0 5.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EMC97612.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EMC97612.1 - 0.00012 22.0 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EMC97612.1 - 0.00099 18.8 0.1 0.0024 17.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMC97612.1 - 0.002 18.4 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EMC97612.1 - 0.0035 17.9 0.0 0.0056 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMC97612.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EMC97612.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EMC97612.1 - 0.023 14.4 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMC97612.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EMC97612.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EMC97612.1 - 0.04 14.4 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 EMC97612.1 - 0.055 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 EMC97612.1 - 0.079 12.9 0.4 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RuvB_N PF05496.12 EMC97612.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Dynamin_N PF00350.23 EMC97612.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 EMC97612.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EMC97612.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EMC97612.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EMC97612.1 - 0.19 12.3 0.0 0.39 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Bac_export_2 PF01312.19 EMC97612.1 - 1.9 7.6 4.3 3.4 6.8 4.3 1.4 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Fungal_trans PF04082.18 EMC97613.1 - 2.3e-32 112.1 0.0 3.3e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC97613.1 - 5.5e-07 29.6 7.9 5.5e-07 29.6 7.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4212 PF13937.6 EMC97613.1 - 0.039 14.3 2.1 0.47 10.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Methyltransf_3 PF01596.17 EMC97614.1 - 1.4e-27 96.3 0.0 1.6e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EMC97614.1 - 2.3e-11 44.6 0.0 3.1e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC97614.1 - 6e-09 35.9 0.0 7.4e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMC97614.1 - 9.8e-06 25.1 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EMC97614.1 - 3.9e-05 24.3 0.0 5.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMC97614.1 - 0.00029 20.6 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EMC97614.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 EMC97614.1 - 0.0047 16.9 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EMC97614.1 - 0.028 14.2 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 EMC97614.1 - 0.12 13.1 0.0 0.2 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EMC97614.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DENN PF02141.21 EMC97616.1 - 3.4e-55 186.9 0.5 5.7e-55 186.2 0.5 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EMC97616.1 - 7.3e-16 58.7 0.1 2.1e-15 57.2 0.1 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EMC97616.1 - 2.7e-12 46.5 2.0 6.7e-12 45.2 1.1 2.2 2 0 0 2 2 2 1 dDENN domain C1_2 PF03107.16 EMC97616.1 - 0.015 15.6 7.6 0.036 14.4 7.6 1.6 1 0 0 1 1 1 0 C1 domain C1_1 PF00130.22 EMC97616.1 - 0.06 13.2 9.1 0.099 12.5 9.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPA PF08616.10 EMC97616.1 - 0.17 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis CRAL_TRIO_2 PF13716.6 EMC97617.1 - 8e-29 100.6 0.0 1.3e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 EMC97617.1 - 1.6e-18 67.0 0.0 2.9e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 EMC97617.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain Asn_synthase PF00733.21 EMC97618.1 - 6.9e-92 308.8 0.0 3.2e-53 181.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EMC97618.1 - 1.5e-38 131.5 0.0 2.7e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EMC97618.1 - 2.9e-29 101.9 0.0 5e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EMC97618.1 - 5e-06 26.1 0.0 9.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EMC97618.1 - 0.04 13.0 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Porin_3 PF01459.22 EMC97619.1 - 1.8e-54 185.0 5.5 2.2e-54 184.7 5.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin P_proprotein PF01483.20 EMC97619.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain Chorismate_synt PF01264.21 EMC97620.1 - 2.5e-135 450.4 0.0 2.9e-135 450.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Methyltransf_23 PF13489.6 EMC97623.1 - 1.1e-18 67.6 0.1 2.7e-17 63.1 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC97623.1 - 1.3e-16 61.0 0.0 2.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC97623.1 - 1.3e-14 54.7 0.0 2.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC97623.1 - 2.2e-13 50.3 0.0 3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMC97623.1 - 1.7e-12 47.3 0.0 2.3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EMC97623.1 - 9.4e-11 42.3 0.0 1.4e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC97623.1 - 4e-06 26.3 0.0 8e-05 22.1 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EMC97623.1 - 5.6e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EMC97623.1 - 0.00015 21.3 0.0 0.00033 20.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EMC97623.1 - 0.0005 20.0 0.0 0.00087 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EMC97623.1 - 0.0019 17.8 0.0 0.0038 16.8 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 EMC97623.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.6 EMC97623.1 - 0.012 16.6 0.0 0.025 15.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 EMC97623.1 - 0.036 13.0 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Met_10 PF02475.16 EMC97623.1 - 0.045 13.5 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein TehB PF03848.14 EMC97623.1 - 0.051 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_20 PF12147.8 EMC97623.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.10 EMC97623.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DREV PF05219.12 EMC97623.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FAD_binding_4 PF01565.23 EMC97624.1 - 8.2e-20 71.0 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Alg14 PF08660.11 EMC97625.1 - 1e-51 175.3 0.0 4.7e-51 173.2 0.0 1.8 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like IF-2B PF01008.17 EMC97626.1 - 1.6e-54 185.0 2.0 3.8e-32 111.6 0.0 2.9 2 1 0 2 2 2 2 Initiation factor 2 subunit family YAcAr PF10686.9 EMC97626.1 - 0.032 14.2 2.0 0.33 10.9 0.0 3.0 2 1 1 3 3 3 0 YspA, cpYpsA-related SLOG family Polysacc_deac_1 PF01522.21 EMC97627.1 - 3.6e-19 68.9 0.0 6.2e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EMC97627.1 - 1.2e-10 41.5 0.1 2e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 EMC97627.1 - 0.0013 17.2 0.0 0.0019 16.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Glyco_hydro_57 PF03065.15 EMC97627.1 - 0.066 12.4 0.2 0.28 10.3 0.0 1.9 2 1 1 3 3 3 0 Glycosyl hydrolase family 57 AAT PF03417.16 EMC97628.1 - 6.9e-31 107.7 0.0 8.4e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase bZIP_2 PF07716.15 EMC97629.1 - 0.0035 17.4 0.2 0.01 15.9 0.2 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Spc7 PF08317.11 EMC97629.1 - 0.045 12.6 8.4 10 4.9 0.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Borealin PF10512.9 EMC97629.1 - 0.055 13.4 0.6 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 Cell division cycle-associated protein 8 YlqD PF11068.8 EMC97629.1 - 0.08 13.3 4.9 0.18 12.2 4.9 1.6 1 0 0 1 1 1 0 YlqD protein DUF4407 PF14362.6 EMC97629.1 - 0.11 11.9 11.6 0.12 11.7 10.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4618 PF15397.6 EMC97629.1 - 0.21 10.9 8.2 2.3 7.6 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Mis14 PF08641.12 EMC97629.1 - 0.22 11.8 5.0 0.17 12.2 3.3 1.7 2 0 0 2 2 2 0 Kinetochore protein Mis14 like DUF4665 PF15679.5 EMC97629.1 - 0.24 12.0 4.1 0.25 12.0 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) Phasin PF05597.11 EMC97629.1 - 0.42 10.6 5.8 0.36 10.8 1.3 2.8 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PRKG1_interact PF15898.5 EMC97629.1 - 0.46 11.4 5.4 1.8 9.5 5.4 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain KfrA_N PF11740.8 EMC97629.1 - 0.78 10.4 9.5 0.26 12.0 0.7 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term OEP PF02321.18 EMC97629.1 - 1.2 8.9 7.3 3.7 7.3 7.3 1.7 1 1 0 1 1 1 0 Outer membrane efflux protein Glutaredoxin PF00462.24 EMC97630.1 - 1.8e-15 56.9 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.19 EMC97631.1 - 1.1e-45 155.2 0.0 2.4e-45 154.1 0.0 1.5 1 1 0 1 1 1 1 Flavoprotein DUF997 PF06196.12 EMC97632.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF997) Glyco_hydro_10 PF00331.20 EMC97633.1 - 7.4e-76 255.3 1.9 9.5e-76 255.0 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 SOG2 PF10428.9 EMC97633.1 - 5.3 6.1 19.3 8.7 5.4 19.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein 4F5 PF04419.14 EMC97634.1 - 9.1e-10 39.2 13.8 9.1e-10 39.2 13.8 1.5 2 0 0 2 2 2 1 4F5 protein family OAD_gamma PF04277.13 EMC97634.1 - 0.16 12.6 2.3 0.16 12.6 2.3 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Motile_Sperm PF00635.26 EMC97635.1 - 1.3e-25 89.3 0.0 3.2e-25 88.1 0.0 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain OAF PF14941.6 EMC97635.1 - 0.013 14.9 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator, Out at first TBCC_N PF16752.5 EMC97635.1 - 0.016 15.6 1.0 0.033 14.6 1.0 1.4 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Selenoprotein_S PF06936.11 EMC97635.1 - 0.022 14.6 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Baculo_PEP_C PF04513.12 EMC97635.1 - 0.042 13.9 3.6 0.076 13.1 3.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EMC97635.1 - 0.061 12.7 4.5 0.091 12.1 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAM-associated PF14303.6 EMC97635.1 - 0.086 13.6 3.2 0.1 13.3 2.6 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Fzo_mitofusin PF04799.13 EMC97635.1 - 0.098 12.2 1.3 0.17 11.4 1.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF2452 PF10504.9 EMC97635.1 - 0.58 9.6 2.6 0.94 8.9 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) UBX PF00789.20 EMC97636.1 - 1.1e-06 28.7 0.4 4.1e-06 26.9 0.0 2.1 3 0 0 3 3 3 1 UBX domain UBA PF00627.31 EMC97636.1 - 0.0012 18.7 0.0 0.0033 17.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF572 PF04502.13 EMC97636.1 - 0.007 16.0 22.5 0.011 15.4 22.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) UBA_3 PF09288.10 EMC97636.1 - 0.019 14.8 0.4 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain SOBP PF15279.6 EMC97636.1 - 0.083 13.5 6.4 0.094 13.3 6.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Draxin PF15550.6 EMC97636.1 - 0.43 10.4 17.1 0.57 10.0 17.1 1.2 1 0 0 1 1 1 0 Draxin CDC45 PF02724.14 EMC97636.1 - 1.1 7.4 14.8 1.3 7.2 14.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Atg14 PF10186.9 EMC97636.1 - 1.2 8.1 15.4 1.7 7.7 15.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ArfGap PF01412.18 EMC97636.1 - 4.5 7.4 9.8 0.16 12.0 2.3 2.2 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf GAGA_bind PF06217.12 EMC97636.1 - 6.3 7.0 15.9 8.7 6.5 15.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DAO PF01266.24 EMC97637.1 - 2e-51 175.6 0.1 6.3e-51 174.0 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 EMC97637.1 - 2.4e-44 150.2 0.0 4.7e-44 149.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EMC97637.1 - 2e-09 37.1 0.1 4.4e-09 35.9 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EMC97637.1 - 5.9e-06 25.9 0.2 0.0001 21.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC97637.1 - 8.9e-05 21.9 0.1 0.00027 20.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EMC97637.1 - 0.0019 18.1 0.1 0.0043 17.0 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EMC97637.1 - 0.003 16.7 0.1 0.016 14.3 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EMC97637.1 - 0.012 15.8 0.2 0.05 13.8 0.2 2.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMC97637.1 - 0.016 14.0 0.4 0.029 13.1 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EMC97637.1 - 0.07 12.4 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC97637.1 - 0.094 13.3 0.2 0.41 11.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC97637.1 - 0.16 11.2 0.4 0.77 8.9 0.4 2.0 1 1 0 1 1 1 0 FAD binding domain FANCI_HD1 PF14679.6 EMC97638.1 - 0.025 14.5 0.0 0.029 14.3 0.0 1.0 1 0 0 1 1 1 0 FANCI helical domain 1 zf-H2C2_2 PF13465.6 EMC97639.1 - 2.9e-13 49.6 6.8 2.1e-07 31.1 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EMC97639.1 - 1.5e-12 47.2 13.3 4.1e-06 27.0 2.4 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC97639.1 - 2.5e-08 34.1 10.6 0.00095 19.8 1.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMC97639.1 - 3.5e-07 30.1 6.0 0.0023 17.9 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMC97639.1 - 3.8e-06 27.0 0.7 0.069 13.5 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC97639.1 - 4.9e-05 23.6 1.2 0.014 15.8 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EMC97639.1 - 0.001 18.8 4.3 0.098 12.4 0.6 3.6 3 0 0 3 3 3 1 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 EMC97639.1 - 0.048 14.2 0.7 0.12 13.0 0.7 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 EMC97639.1 - 0.066 13.5 1.7 0.17 12.2 1.7 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EMC97639.1 - 0.55 10.7 2.6 13 6.3 0.4 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 EMC97639.1 - 0.91 9.8 3.9 13 6.1 0.2 2.4 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 EMC97639.1 - 7.1 6.9 6.2 41 4.4 1.4 2.4 1 1 1 2 2 2 0 NSD Cys-His rich domain FMN_dh PF01070.18 EMC97640.1 - 1.7e-106 356.2 0.0 2.1e-106 355.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMC97640.1 - 2.5e-05 23.5 0.3 4.1e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EMC97640.1 - 0.002 17.6 0.3 0.0028 17.1 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EMC97640.1 - 0.0034 16.6 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EMC97640.1 - 0.0056 16.2 0.4 0.23 10.9 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 EMC97640.1 - 0.03 13.6 0.2 0.57 9.4 0.2 2.2 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG Glyco_transf_22 PF03901.17 EMC97642.1 - 8.9e-82 275.5 4.0 1.2e-81 275.1 4.0 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2645 PF10840.8 EMC97642.1 - 0.039 14.6 0.2 0.16 12.6 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) GT87 PF09594.10 EMC97643.1 - 0.0058 16.4 1.0 0.0093 15.7 0.4 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 87 TrbC PF04956.13 EMC97643.1 - 0.048 13.9 0.7 0.048 13.9 0.7 2.3 2 1 1 3 3 3 0 TrbC/VIRB2 family MAP17 PF15807.5 EMC97643.1 - 0.25 11.6 2.0 1.8 8.8 0.0 2.6 2 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Utp14 PF04615.13 EMC97643.1 - 2.2 6.8 18.2 3.2 6.2 18.2 1.2 1 0 0 1 1 1 0 Utp14 protein AAA PF00004.29 EMC97645.1 - 3.3e-15 56.7 0.0 6.7e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMC97645.1 - 7.1e-05 23.1 1.2 0.068 13.4 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 EMC97645.1 - 0.0011 19.4 1.5 0.038 14.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain PRA-PH PF01503.17 EMC97645.1 - 0.056 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase AAA_19 PF13245.6 EMC97645.1 - 0.13 12.6 0.0 0.69 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Torsin PF06309.11 EMC97645.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Torsin RuvB_N PF05496.12 EMC97645.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DASH_Dad2 PF08654.10 EMC97646.1 - 5.6e-25 87.6 1.7 7.1e-25 87.3 1.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 EMC97646.1 - 0.0015 18.2 0.2 0.0022 17.7 0.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 Seryl_tRNA_N PF02403.22 EMC97646.1 - 0.014 15.7 0.6 0.018 15.3 0.6 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IFT20 PF14931.6 EMC97646.1 - 0.025 14.7 2.4 0.061 13.5 2.6 1.5 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 HAUS2 PF15003.6 EMC97646.1 - 0.033 13.9 0.2 0.043 13.5 0.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 NPV_P10 PF05531.12 EMC97646.1 - 0.072 13.6 1.2 0.1 13.1 1.2 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Shugoshin_N PF07558.11 EMC97647.1 - 8.4e-17 60.8 4.3 1.6e-16 59.8 4.3 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EMC97647.1 - 5.1e-11 42.1 5.0 5.1e-11 42.1 5.0 2.6 2 0 0 2 2 2 1 Shugoshin C terminus CCDC85 PF10226.9 EMC97647.1 - 0.058 13.1 0.4 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 CCDC85 family CASP_C PF08172.12 EMC97647.1 - 0.41 10.0 2.6 1.1 8.6 2.6 1.7 1 0 0 1 1 1 0 CASP C terminal CRM1_C PF08767.11 EMC97648.1 - 4.5e-133 443.4 4.4 1.1e-132 442.1 1.2 2.7 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 EMC97648.1 - 8.5e-39 133.0 8.4 1.2e-38 132.4 2.1 4.0 3 1 1 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EMC97648.1 - 2e-33 113.8 3.5 4.9e-33 112.6 2.8 2.1 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EMC97648.1 - 1.2e-29 102.2 1.8 2.9e-29 100.9 0.7 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EMC97648.1 - 3.1e-20 71.4 2.9 8.7e-20 70.0 2.9 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EMC97648.1 - 7.3e-13 48.2 0.0 3.2e-12 46.2 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EMC97648.1 - 0.0019 18.1 2.9 0.22 11.4 0.0 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) BID PF06393.11 EMC97648.1 - 0.024 14.2 0.3 0.073 12.6 0.3 1.8 1 0 0 1 1 1 0 BH3 interacting domain (BID) HD_assoc PF13286.6 EMC97648.1 - 0.1 13.1 2.1 25 5.5 0.0 3.7 4 0 0 4 4 4 0 Phosphohydrolase-associated domain Vac14_Fab1_bd PF12755.7 EMC97648.1 - 0.45 11.1 2.9 15 6.3 0.0 4.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region PPI_Ypi1 PF07491.11 EMC97649.1 - 2.8e-24 84.7 0.8 5.3e-24 83.8 0.8 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.12 EMC97649.1 - 0.0074 14.9 7.7 0.0074 14.9 7.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ecl1 PF12855.7 EMC97652.1 - 2.6e-13 51.5 27.3 3.1e-13 51.2 27.3 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins YacG PF03884.14 EMC97652.1 - 0.058 13.1 1.3 0.058 13.1 1.3 1.9 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Form_Nir_trans PF01226.17 EMC97653.1 - 6.3e-75 251.5 26.4 7.7e-75 251.3 26.4 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter DUF4142 PF13628.6 EMC97655.1 - 0.03 14.6 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) adh_short_C2 PF13561.6 EMC97656.1 - 2.4e-54 184.4 0.0 2.9e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC97656.1 - 6.2e-42 143.3 0.0 1.1e-41 142.4 0.0 1.4 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 EMC97656.1 - 1.2e-08 35.1 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF460 PF04312.13 EMC97656.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) THF_DHG_CYH_C PF02882.19 EMC97656.1 - 0.099 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain EMP24_GP25L PF01105.24 EMC97657.1 - 3.4e-48 164.0 0.0 3.9e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FA_desaturase PF00487.24 EMC97658.1 - 6e-23 82.0 16.3 8.7e-23 81.5 16.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EMC97658.1 - 4.7e-19 67.6 0.0 7.4e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M8 PF01457.16 EMC97658.1 - 0.087 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Leishmanolysin HeLo PF14479.6 EMC97659.1 - 3.5e-43 147.8 0.1 6.3e-43 147.0 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation p450 PF00067.22 EMC97660.1 - 2e-28 99.4 0.0 7.8e-28 97.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Alba PF01918.21 EMC97663.1 - 0.00035 20.3 0.1 0.00051 19.8 0.1 1.3 1 0 0 1 1 1 1 Alba Aminotran_4 PF01063.19 EMC97664.1 - 9.9e-25 87.7 0.0 2.2e-24 86.5 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV Alb1 PF09135.11 EMC97667.1 - 0.019 15.9 0.3 0.062 14.2 0.1 1.8 2 0 0 2 2 2 0 Alb1 GAS PF13851.6 EMC97668.1 - 0.001 18.4 4.1 0.001 18.4 4.1 1.6 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 EMC97668.1 - 0.0036 17.6 0.8 0.0036 17.6 0.8 2.2 2 1 1 3 3 3 1 Csm1 N-terminal domain Sec2p PF06428.11 EMC97668.1 - 0.02 14.8 2.8 0.046 13.7 2.8 1.6 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p TPR_MLP1_2 PF07926.12 EMC97668.1 - 0.16 12.0 9.6 0.1 12.7 2.2 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 EMC97668.1 - 0.4 10.8 8.7 0.74 9.9 4.9 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 EMC97668.1 - 1.1 8.0 9.2 0.29 10.0 5.1 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 EMC97668.1 - 1.5 8.7 7.8 5.2 6.9 0.3 3.1 2 1 1 3 3 3 0 Septum formation initiator DUF724 PF05266.14 EMC97668.1 - 2.5 7.9 6.2 1.5 8.6 4.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 EMC97668.1 - 3.1 8.3 10.4 37 4.8 10.4 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4200 PF13863.6 EMC97668.1 - 4.3 7.8 12.8 64 4.0 6.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Acetyltransf_1 PF00583.25 EMC97669.1 - 5.4e-11 42.7 0.0 8.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC97669.1 - 4e-07 30.0 0.1 5.7e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC97669.1 - 1.2e-05 25.2 0.1 2.1e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EMC97669.1 - 0.00012 22.4 0.0 0.00022 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EMC97669.1 - 0.01 15.9 0.1 0.018 15.1 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EMC97669.1 - 0.029 13.9 0.2 0.048 13.1 0.1 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_4 PF13420.7 EMC97669.1 - 0.035 14.3 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TAP_C PF03943.13 EMC97670.1 - 1.2e-12 47.2 0.0 8.5e-07 28.5 0.0 3.7 4 0 0 4 4 4 3 TAP C-terminal domain DUF1242 PF06842.12 EMC97671.1 - 2.9e-17 62.1 1.1 4.6e-17 61.5 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF624 PF04854.14 EMC97671.1 - 0.0063 16.6 0.3 0.008 16.3 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF624 DUF418 PF04235.12 EMC97671.1 - 0.02 14.8 0.3 0.02 14.8 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF418) LST1 PF05083.13 EMC97671.1 - 0.68 10.3 2.3 0.47 10.8 1.0 1.4 1 1 0 1 1 1 0 LST-1 protein TFIID-18kDa PF02269.16 EMC97672.1 - 5e-14 52.1 0.1 3.1e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 EMC97672.1 - 0.13 12.7 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 CENP-S protein MitMem_reg PF13012.6 EMC97673.1 - 1.9e-19 70.1 1.0 3.4e-19 69.3 0.4 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EMC97673.1 - 2.5e-19 69.4 0.0 5.1e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 EMC97673.1 - 2.2e-06 27.8 0.0 4.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) UTP25 PF06862.12 EMC97674.1 - 6.1e-176 585.8 0.0 7.2e-176 585.6 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EMC97674.1 - 0.13 12.0 0.0 0.5 10.1 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase zf-HIT PF04438.16 EMC97675.1 - 0.074 12.9 4.8 0.12 12.3 4.8 1.4 1 0 0 1 1 1 0 HIT zinc finger Herpes_capsid PF06112.11 EMC97675.1 - 2 8.5 12.5 2.4 8.2 12.5 1.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein adh_short PF00106.25 EMC97677.1 - 1.4e-10 41.0 0.0 3.3e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC97677.1 - 9.3e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC97677.1 - 0.0069 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 KR domain PRELI PF04707.14 EMC97678.1 - 1.1e-35 122.8 0.0 1.3e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Tcp11 PF05794.13 EMC97679.1 - 7.2e-98 328.6 0.1 2.2e-97 326.9 0.0 1.8 2 0 0 2 2 2 1 T-complex protein 11 AA_kinase PF00696.28 EMC97680.1 - 6.8e-42 143.7 0.2 1.1e-41 143.0 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 EMC97680.1 - 1.6e-12 47.0 0.5 8.8e-08 31.8 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EMC97680.1 - 8.1e-09 35.1 0.6 2.5e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 ACT domain ADH_zinc_N_2 PF13602.6 EMC97681.1 - 1.8e-15 58.2 0.0 3.7e-15 57.2 0.0 1.5 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMC97681.1 - 9.8e-07 28.8 1.1 1.2e-05 25.3 1.1 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC97681.1 - 0.17 11.8 1.1 12 5.8 0.1 3.0 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain MDD_C PF18376.1 EMC97685.1 - 3.6e-66 222.5 0.1 6.5e-66 221.6 0.1 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EMC97685.1 - 2.1e-09 37.5 1.0 5.5e-09 36.1 1.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.17 EMC97686.1 - 3.2e-41 141.9 10.1 4.5e-37 128.2 2.5 3.0 1 1 0 2 2 2 2 Cytochrome c/c1 heme lyase DAO PF01266.24 EMC97688.1 - 7.2e-37 127.8 0.6 1.1e-36 127.2 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMC97688.1 - 3.1e-05 24.0 0.5 0.016 15.2 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMC97688.1 - 8.7e-05 22.7 0.1 0.00028 21.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC97688.1 - 0.00016 21.0 0.0 0.063 12.5 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC97688.1 - 0.00018 20.8 0.2 0.046 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC97688.1 - 0.001 17.9 0.0 0.1 11.3 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMC97688.1 - 0.0027 16.9 3.1 0.016 14.3 3.1 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EMC97688.1 - 0.0047 16.2 0.0 0.012 14.9 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EMC97688.1 - 0.037 14.6 0.1 19 5.9 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMC97688.1 - 0.038 13.0 0.1 0.14 11.2 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EMC97688.1 - 0.21 10.6 1.3 0.7 8.9 0.3 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A MIP PF00230.20 EMC97689.1 - 4.7e-27 95.2 11.5 6.4e-27 94.7 11.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein TatD_DNase PF01026.21 EMC97690.1 - 3.8e-51 173.9 0.0 4.9e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase YL1_C PF08265.11 EMC97690.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain GYF PF02213.16 EMC97691.1 - 4.3e-13 48.7 0.7 1.1e-12 47.4 0.7 1.7 1 0 0 1 1 1 1 GYF domain Secretin_N_2 PF07655.13 EMC97691.1 - 0.73 10.4 2.6 1.4 9.5 0.2 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Brix PF04427.18 EMC97692.1 - 7.2e-24 85.0 0.0 1.2e-23 84.3 0.0 1.3 1 0 0 1 1 1 1 Brix domain zf-CCHH PF10283.9 EMC97693.1 - 0.25 11.4 2.4 1.6 8.8 0.9 2.2 2 0 0 2 2 2 0 PBZ domain HGTP_anticodon PF03129.20 EMC97695.1 - 4.4e-19 68.4 0.3 1.2e-18 67.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EMC97695.1 - 8.2e-08 32.4 0.4 4e-07 30.2 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) CBFD_NFYB_HMF PF00808.23 EMC97696.1 - 3.6e-19 68.8 0.5 5.3e-19 68.3 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMC97696.1 - 1.2e-14 54.8 0.2 2.1e-14 54.0 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EMC97696.1 - 0.057 13.8 0.2 0.1 12.9 0.1 1.5 2 0 0 2 2 2 0 CENP-S associating Centromere protein X TRAPP PF04051.16 EMC97697.1 - 9.7e-45 151.9 0.0 1.3e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2559 PF10832.8 EMC97697.1 - 0.075 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) Tat PF00539.18 EMC97698.1 - 0.0095 16.1 1.0 0.015 15.4 1.0 1.3 1 0 0 1 1 1 1 Transactivating regulatory protein (Tat) R3H PF01424.22 EMC97699.1 - 5.8e-12 45.4 0.1 1.1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EMC97699.1 - 1.9e-07 30.8 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M66 PF10462.9 EMC97699.1 - 0.0097 14.9 0.1 0.018 14.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase M66 Spc7 PF08317.11 EMC97700.1 - 0.008 15.1 6.4 0.018 13.9 6.4 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin PF00261.20 EMC97700.1 - 0.013 14.9 12.4 0.024 14.0 12.4 1.3 1 0 0 1 1 1 0 Tropomyosin Cnn_1N PF07989.11 EMC97700.1 - 0.014 15.5 4.7 1.7 8.9 2.0 2.8 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Golgin_A5 PF09787.9 EMC97700.1 - 0.09 12.2 11.4 0.079 12.4 10.0 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 ZapB PF06005.12 EMC97700.1 - 0.12 12.8 12.5 2.4 8.7 9.9 2.9 2 1 1 3 3 3 0 Cell division protein ZapB DUF4763 PF15960.5 EMC97700.1 - 0.15 11.3 8.1 2.8 7.2 5.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) UPF0242 PF06785.11 EMC97700.1 - 0.16 12.0 9.5 0.1 12.7 7.4 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 EMC97700.1 - 0.16 11.5 13.1 0.19 11.3 11.5 1.7 2 0 0 2 2 2 0 Intermediate filament protein ADIP PF11559.8 EMC97700.1 - 0.88 9.6 9.3 2 8.5 9.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 EMC97700.1 - 1.3 9.2 15.0 0.18 12.0 9.1 2.4 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Sec3_C_2 PF15278.6 EMC97700.1 - 1.7 9.0 4.5 16 5.9 0.6 3.0 2 1 1 3 3 3 0 Sec3 exocyst complex subunit FlaC_arch PF05377.11 EMC97700.1 - 1.8 9.0 5.2 14 6.1 0.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 EMC97700.1 - 2 7.4 6.5 3.5 6.6 6.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 EMC97700.1 - 3.7 8.2 15.1 19 6.0 11.1 2.9 3 1 0 3 3 2 0 SlyX DUF2570 PF10828.8 EMC97700.1 - 5.8 6.8 9.2 4.6 7.1 6.8 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) TMPIT PF07851.13 EMC97700.1 - 6.9 5.8 5.0 11 5.2 5.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein TPR_2 PF07719.17 EMC97701.1 - 2.9e-07 30.1 1.4 0.0028 17.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EMC97701.1 - 3.1e-05 23.6 0.0 0.41 10.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMC97701.1 - 0.00019 21.6 0.3 0.2 12.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMC97701.1 - 0.0014 19.2 1.2 3.8 8.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EMC97701.1 - 0.036 13.8 0.2 5.2 6.8 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 EMC97701.1 - 0.083 13.0 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MARVEL PF01284.23 EMC97702.1 - 1.5e-06 28.3 12.1 2.2e-06 27.7 12.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain Opacity PF02462.15 EMC97702.1 - 0.043 13.9 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Opacity family porin protein DUF3593 PF12159.8 EMC97702.1 - 0.072 13.1 1.0 0.85 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) HRG PF16954.5 EMC97702.1 - 0.2 12.1 0.2 0.2 12.1 0.2 2.8 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF89 PF01937.19 EMC97703.1 - 5.4e-132 440.0 0.0 6.3e-132 439.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF1996 PF09362.10 EMC97704.1 - 9.5e-54 182.9 0.3 2e-53 181.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EMC97704.1 - 2.1e-42 143.2 42.5 2e-14 53.5 10.8 3.6 3 0 0 3 3 3 3 WSC domain TAP_C PF03943.13 EMC97704.1 - 0.58 9.8 2.0 0.88 9.3 0.5 2.1 2 0 0 2 2 2 0 TAP C-terminal domain Sugarporin_N PF11471.8 EMC97705.1 - 0.00039 20.3 7.7 0.024 14.6 2.3 3.2 2 1 1 3 3 3 2 Maltoporin periplasmic N-terminal extension Exonuc_VII_L PF02601.15 EMC97705.1 - 0.062 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran_CTD PF16326.5 EMC97705.1 - 0.14 12.4 3.3 0.61 10.4 0.6 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain YvrJ PF12841.7 EMC97705.1 - 0.17 11.5 1.1 42 3.8 0.0 3.7 3 1 1 4 4 4 0 YvrJ protein family CLZ PF16526.5 EMC97705.1 - 0.22 11.9 3.4 3.1 8.2 1.4 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Myb_DNA-binding PF00249.31 EMC97706.1 - 0.00047 20.3 0.0 0.00081 19.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain TT_ORF2 PF02957.15 EMC97706.1 - 0.32 11.9 3.5 0.43 11.5 3.5 1.2 1 0 0 1 1 1 0 TT viral ORF2 DTHCT PF08070.11 EMC97706.1 - 1.3 9.8 8.4 3 8.6 8.1 1.6 1 1 0 1 1 1 0 DTHCT (NUC029) region CMAS PF02353.20 EMC97707.1 - 7.5e-35 120.5 0.8 1.3e-34 119.8 0.8 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EMC97707.1 - 8.9e-12 45.0 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC97707.1 - 1.3e-11 45.0 0.0 2.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC97707.1 - 2.1e-11 44.4 0.0 3.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC97707.1 - 5.6e-11 43.1 0.0 9.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC97707.1 - 2.9e-10 40.2 0.0 4.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC97707.1 - 5.6e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EMC97707.1 - 0.00029 20.4 0.0 0.00066 19.2 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltr_RsmB-F PF01189.17 EMC97707.1 - 0.00072 19.2 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EMC97707.1 - 0.0012 18.7 0.0 0.0054 16.5 0.0 2.0 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 EMC97707.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.20 EMC97707.1 - 0.0046 16.1 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 EMC97707.1 - 0.007 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 EMC97707.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase GidB PF02527.15 EMC97707.1 - 0.055 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G P5-ATPase PF12409.8 EMC97708.1 - 1.1e-40 138.6 0.2 3.6e-40 136.9 0.2 2.0 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EMC97708.1 - 1.9e-28 99.2 0.1 7.3e-28 97.3 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMC97708.1 - 8.6e-16 58.9 0.5 2.7e-08 34.4 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EMC97708.1 - 2.6e-05 24.0 5.2 2.6e-05 24.0 5.2 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EMC97708.1 - 0.00032 20.3 0.0 0.00071 19.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EMC97708.1 - 0.0029 17.7 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EMC97708.1 - 0.003 17.3 0.1 0.72 9.5 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PI3K_1B_p101 PF10486.9 EMC97708.1 - 1.9 6.1 6.4 2.8 5.6 6.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TPR_1 PF00515.28 EMC97709.1 - 3.3e-07 29.8 3.5 0.21 11.4 0.1 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EMC97709.1 - 8.8e-05 22.9 22.4 0.022 15.3 0.4 7.5 8 1 1 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMC97709.1 - 0.00027 21.5 27.3 0.43 11.5 0.2 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMC97709.1 - 0.0027 17.8 13.8 0.26 11.6 0.4 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC97709.1 - 0.0055 16.7 20.2 0.19 11.9 0.3 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EMC97709.1 - 0.01 16.2 4.7 0.46 11.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EMC97709.1 - 0.62 10.2 4.8 4.6 7.4 0.1 3.8 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EMC97709.1 - 1.8 8.9 20.8 7.5 6.9 0.2 7.9 10 0 0 10 10 10 0 Tetratricopeptide repeat RIX1 PF08167.12 EMC97710.1 - 1.2e-56 191.5 3.6 4.1e-56 189.7 3.6 2.0 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis NADH_B2 PF14813.6 EMC97711.1 - 0.027 14.3 0.2 0.03 14.1 0.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.25 EMC97712.1 - 1.3e-65 221.4 0.0 1.7e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97712.1 - 2.5e-27 95.8 0.0 4.1e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMC97712.1 - 0.0092 14.8 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EMC97712.1 - 0.16 11.3 0.0 0.53 9.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 EMC97712.1 - 0.2 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain rRNA_proc-arch PF13234.6 EMC97713.1 - 6.1e-83 278.9 0.0 1.3e-82 277.8 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EMC97713.1 - 2.3e-56 190.0 3.1 6.3e-56 188.6 3.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EMC97713.1 - 7.9e-19 68.1 0.0 3.3e-18 66.1 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC97713.1 - 4.9e-07 30.1 0.0 2.8e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC97713.1 - 5.7e-06 26.4 0.0 1.8e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BRE1 PF08647.11 EMC97713.1 - 0.019 15.0 1.5 0.019 15.0 1.5 2.8 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase STATa_Ig PF18214.1 EMC97713.1 - 0.022 14.8 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain ATPase_2 PF01637.18 EMC97713.1 - 0.026 14.4 0.1 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 EMC97713.1 - 0.041 13.0 0.0 0.089 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4600 PF15372.6 EMC97713.1 - 4.5 7.7 9.8 3.3 8.1 1.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) ABC1 PF03109.16 EMC97717.1 - 9.4e-32 109.7 0.0 1.5e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family UQ_con PF00179.26 EMC97718.1 - 9.8e-48 161.4 0.0 1.1e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMC97718.1 - 0.0028 17.3 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMC97718.1 - 0.14 12.4 0.9 0.23 11.7 0.9 1.7 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.12 EMC97719.1 - 8.1e-67 225.5 6.8 9.1e-67 225.4 6.8 1.0 1 0 0 1 1 1 1 Pex19 protein family FliE PF02049.18 EMC97719.1 - 0.3 11.3 7.1 0.33 11.1 1.1 3.2 3 1 1 4 4 4 0 Flagellar hook-basal body complex protein FliE GET2 PF08690.10 EMC97719.1 - 2.4 7.8 9.4 12 5.4 9.5 2.0 1 1 0 1 1 1 0 GET complex subunit GET2 PPR_2 PF13041.6 EMC97721.1 - 4.4e-21 74.8 0.0 1.5e-11 44.3 0.0 3.9 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EMC97721.1 - 1.4e-12 47.5 0.0 1.4e-07 31.5 0.0 3.2 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 EMC97721.1 - 9.4e-11 41.2 0.0 0.00034 20.6 0.0 4.1 3 0 0 3 3 3 3 PPR repeat PPR_1 PF12854.7 EMC97721.1 - 1.9e-10 40.2 0.0 0.0018 17.9 0.0 3.9 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 EMC97721.1 - 0.00054 19.4 0.1 0.29 10.5 0.0 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP CCDC24 PF15669.5 EMC97721.1 - 0.011 15.6 0.1 0.034 14.0 0.1 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family CBP_BcsN PF17038.5 EMC97721.1 - 0.083 12.3 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN PMBR PF09373.10 EMC97721.1 - 0.11 12.8 0.0 0.42 10.8 0.0 2.1 1 0 0 1 1 1 0 Pseudomurein-binding repeat cwf18 PF08315.12 EMC97722.1 - 9.4e-45 152.6 13.5 4.6e-44 150.4 9.6 2.0 2 0 0 2 2 2 2 cwf18 pre-mRNA splicing factor Pkinase PF00069.25 EMC97724.1 - 3.9e-49 167.4 0.0 3.3e-33 115.2 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMC97724.1 - 9.9e-22 77.4 0.0 2.8e-19 69.4 0.0 3.8 3 1 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC97724.1 - 0.00049 19.5 0.0 0.002 17.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EMC97724.1 - 0.059 13.3 2.0 0.66 9.9 2.0 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family RGS PF00615.19 EMC97725.1 - 5.3e-10 39.6 0.0 7.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain SAP PF02037.27 EMC97726.1 - 7.8e-07 28.7 0.1 1.4e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 SAP domain DUF3984 PF13136.6 EMC97727.1 - 1.4e-27 97.0 25.9 8.3e-24 84.6 23.7 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3984) p450 PF00067.22 EMC97728.1 - 1.3e-60 205.5 0.0 1.8e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cut8 PF08559.10 EMC97729.1 - 6.3e-76 255.2 0.0 8.1e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DIE2_ALG10 PF04922.12 EMC97731.1 - 1.1e-124 416.8 7.4 1.3e-124 416.5 7.4 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 EMC97732.1 - 8.6e-29 100.2 0.0 1.3e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Ribosomal_L3 PF00297.22 EMC97733.1 - 2.9e-18 66.0 5.4 1e-14 54.4 2.3 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Hexapep PF00132.24 EMC97736.1 - 4.7e-10 38.8 12.6 2.9e-07 30.0 3.1 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 EMC97736.1 - 8e-09 35.5 11.2 1.7e-08 34.5 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.6 EMC97736.1 - 7e-08 32.1 12.4 1.8e-05 24.4 5.7 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EMC97736.1 - 9.9e-07 28.9 0.1 3.2e-06 27.3 0.1 2.0 1 0 0 1 1 1 1 Maltose acetyltransferase EamA PF00892.20 EMC97737.1 - 3e-10 40.4 40.3 7.1e-07 29.5 7.0 3.2 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 EMC97737.1 - 3.4e-07 29.6 13.5 1e-06 28.0 13.5 1.7 1 1 0 1 1 1 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 EMC97737.1 - 6.8e-07 28.7 12.2 1.9e-06 27.3 12.2 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter Mpp10 PF04006.12 EMC97738.1 - 8.5e-107 358.1 11.3 1.7e-106 357.1 11.3 1.5 1 1 0 1 1 1 1 Mpp10 protein bZIP_2 PF07716.15 EMC97739.1 - 7.3e-12 45.2 13.8 8.8e-12 44.9 12.2 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EMC97739.1 - 0.00025 21.1 8.2 0.00061 19.8 8.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 EMC97739.1 - 0.027 14.5 4.3 0.031 14.3 4.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RMI2 PF16100.5 EMC97739.1 - 0.044 13.6 0.1 0.073 12.9 0.1 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 GIT_CC PF16559.5 EMC97739.1 - 0.081 12.8 0.5 0.16 11.9 0.5 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TRAF_BIRC3_bd PF16673.5 EMC97739.1 - 0.1 12.4 1.7 0.3 10.9 1.7 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain APC_u14 PF16635.5 EMC97739.1 - 0.19 12.3 4.0 0.077 13.5 0.9 2.0 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr MTBP_C PF14920.6 EMC97739.1 - 0.23 11.2 4.9 0.39 10.4 4.9 1.3 1 0 0 1 1 1 0 MDM2-binding SOGA PF11365.8 EMC97739.1 - 0.45 11.7 5.6 0.18 13.0 3.0 1.7 2 0 0 2 2 1 0 Protein SOGA YabA PF06156.13 EMC97739.1 - 0.5 11.0 2.5 0.74 10.5 1.3 1.8 1 1 1 2 2 2 0 Initiation control protein YabA DUF3395 PF11875.8 EMC97739.1 - 0.64 9.9 6.3 1.2 9.0 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) XhlA PF10779.9 EMC97739.1 - 1.5 9.1 5.2 0.27 11.5 1.3 1.7 2 0 0 2 2 2 0 Haemolysin XhlA ZapB PF06005.12 EMC97739.1 - 2.8 8.4 11.0 0.06 13.8 1.9 2.6 3 0 0 3 3 3 0 Cell division protein ZapB CYSTM PF12734.7 EMC97739.1 - 4.6 7.7 11.6 38 4.7 8.2 2.5 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance RNA_pol_L PF01193.24 EMC97743.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyco_hydro_7 PF00840.20 EMC97745.1 - 2e-147 491.5 11.0 2.4e-147 491.2 11.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CAF1C_H4-bd PF12265.8 EMC97746.1 - 7.3e-13 48.6 0.0 1.7e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EMC97746.1 - 1.1e-12 48.2 9.9 9.5e-05 23.1 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC97746.1 - 2.7e-08 34.0 1.1 0.00069 19.9 0.2 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EMC97746.1 - 0.034 13.4 0.0 0.11 11.7 0.1 1.7 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller zn-ribbon_14 PF16503.5 EMC97747.1 - 9.1e-18 63.5 2.9 9.1e-18 63.5 2.9 4.0 5 0 0 5 5 5 1 Zinc-ribbon ATP_bind_3 PF01171.20 EMC97747.1 - 1.9e-17 63.6 0.0 3.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 EMC97747.1 - 0.0052 16.3 0.5 0.0052 16.3 0.5 2.7 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.16 EMC97747.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 EMC97747.1 - 0.88 9.8 4.0 5.6 7.2 0.3 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) SET PF00856.28 EMC97748.1 - 1.7e-12 48.0 0.1 1.7e-12 48.0 0.1 3.6 3 3 0 3 3 3 1 SET domain AWS PF17907.1 EMC97748.1 - 1.4e-06 28.2 7.8 4e-06 26.7 7.8 1.8 1 0 0 1 1 1 1 AWS domain MAS20 PF02064.15 EMC97748.1 - 0.62 10.2 11.0 1.1 9.4 2.7 2.9 2 0 0 2 2 2 0 MAS20 protein import receptor DHHC PF01529.20 EMC97749.1 - 3.3e-33 114.6 1.0 3.3e-33 114.6 1.0 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase SPATA25 PF15218.6 EMC97749.1 - 0.0097 15.7 0.8 0.0097 15.7 0.8 2.6 2 1 1 3 3 3 1 Spermatogenesis-associated protein 25 Bax1-I PF01027.20 EMC97749.1 - 1.4 8.7 5.7 0.34 10.7 0.6 2.0 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 B12D PF06522.11 EMC97750.1 - 0.024 14.4 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Slu7 PF11708.8 EMC97751.1 - 4e-75 253.1 16.1 4.3e-74 249.7 16.1 2.3 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 EMC97751.1 - 0.35 11.0 1.8 0.65 10.2 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Glyoxal_oxid_N PF07250.11 EMC97752.1 - 1e-39 136.2 0.0 5.6e-39 133.8 0.0 2.1 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EMC97752.1 - 2.8e-25 88.4 1.1 8.5e-25 86.9 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.19 EMC97752.1 - 1.3e-15 57.6 55.1 1e-08 35.5 21.3 3.0 3 0 0 3 3 3 2 Chitin recognition protein Putative_PNPOx PF01243.20 EMC97752.1 - 0.0068 16.6 0.0 0.39 10.9 0.0 2.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Fructosamin_kin PF03881.14 EMC97753.1 - 5e-75 252.4 0.0 5.9e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EMC97753.1 - 0.00015 21.8 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EMC97753.1 - 0.0031 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EMC97753.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase ERG4_ERG24 PF01222.17 EMC97754.1 - 1.1e-134 449.5 24.3 1.3e-134 449.2 24.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Jiraiya PF15038.6 EMC97754.1 - 0.4 10.1 1.5 0.78 9.1 1.5 1.4 1 0 0 1 1 1 0 Jiraiya YlaH PF14036.6 EMC97755.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 YlaH-like protein THOC7 PF05615.13 EMC97758.1 - 0.052 13.8 0.6 0.085 13.1 0.2 1.5 2 0 0 2 2 2 0 Tho complex subunit 7 TRAP_alpha PF03896.16 EMC97759.1 - 3.6e-11 42.8 0.1 3.1e-10 39.7 0.1 2.0 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Fimbrial_K88 PF02432.15 EMC97759.1 - 0.009 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Fimbrial, major and minor subunit Vps16_N PF04841.13 EMC97761.1 - 1.1e-96 324.1 0.0 1.5e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EMC97761.1 - 1.4e-95 320.0 0.4 2.2e-95 319.4 0.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EMC97761.1 - 0.0027 17.9 0.0 2.4 8.5 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EMC97761.1 - 0.023 13.8 0.1 1.3 8.0 0.0 3.2 4 0 0 4 4 4 0 Coatomer WD associated region Phasin_2 PF09361.10 EMC97761.1 - 0.032 14.5 1.8 0.07 13.4 0.8 2.2 2 0 0 2 2 2 0 Phasin protein AAA_lid_2 PF17863.1 EMC97762.1 - 4.7e-05 23.1 0.5 8.5e-05 22.3 0.5 1.5 1 0 0 1 1 1 1 AAA lid domain DUF2129 PF09902.9 EMC97762.1 - 0.039 14.0 0.0 8.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) Bestrophin PF01062.21 EMC97763.1 - 2.7e-59 201.0 0.0 3.4e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF2892 PF11127.8 EMC97763.1 - 1.3 9.1 3.9 14 5.8 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) HA2 PF04408.23 EMC97764.1 - 7.3e-17 61.6 1.0 4.9e-16 58.9 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMC97764.1 - 7.1e-15 55.3 0.0 6.9e-14 52.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMC97764.1 - 4.9e-12 46.1 0.0 1.2e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 EMC97764.1 - 5.7e-10 39.5 0.0 1.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 EMC97764.1 - 3e-07 30.4 0.3 7.8e-07 29.0 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase UBA PF00627.31 EMC97764.1 - 5.1e-06 26.3 3.1 0.0063 16.4 0.3 3.1 3 0 0 3 3 3 2 UBA/TS-N domain AAA_29 PF13555.6 EMC97764.1 - 0.0018 18.0 0.1 0.0066 16.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMC97764.1 - 0.0059 16.9 2.5 0.029 14.6 1.6 2.6 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 EMC97764.1 - 0.037 13.1 0.1 0.068 12.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EMC97764.1 - 0.041 13.2 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 EMC97764.1 - 0.077 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain EHN PF06441.12 EMC97765.1 - 3.5e-31 107.8 0.2 7.3e-31 106.7 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMC97765.1 - 5.7e-11 42.5 0.0 9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC97765.1 - 0.098 13.2 1.8 0.43 11.1 1.8 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Acetyltransf_2 PF00797.17 EMC97767.1 - 6e-41 140.8 0.0 1.3e-40 139.7 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 EMC97767.1 - 0.0019 18.6 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF728 PF05304.12 EMC97767.1 - 0.048 13.5 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF728) F_bP_aldolase PF01116.20 EMC97768.1 - 6.8e-79 265.3 0.4 7.6e-79 265.1 0.4 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Epimerase PF01370.21 EMC97769.1 - 6.4e-21 74.9 0.0 8.5e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC97769.1 - 1.2e-13 51.3 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMC97769.1 - 1.4e-12 47.3 0.0 1.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EMC97769.1 - 2.9e-06 26.6 0.0 7.1e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EMC97769.1 - 8.7e-05 21.8 0.1 0.19 10.9 0.1 2.5 1 1 1 2 2 2 2 Male sterility protein Ldh_1_N PF00056.23 EMC97769.1 - 0.02 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EMC97769.1 - 0.049 13.5 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 EMC97769.1 - 0.094 12.2 0.0 0.51 9.8 0.0 2.2 2 1 0 2 2 2 0 short chain dehydrogenase Acid_PPase PF12689.7 EMC97770.1 - 1.4e-60 204.0 0.0 1.6e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase YTH PF04146.15 EMC97771.1 - 2.3e-11 43.9 0.0 3.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain HORMA PF02301.18 EMC97773.1 - 1.8e-26 93.0 0.0 3.7e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 EMC97773.1 - 3e-08 33.4 7.1 8e-08 32.1 7.1 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EMC97773.1 - 0.0041 17.0 4.6 0.0094 15.9 4.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 EMC97773.1 - 0.04 13.5 2.2 0.092 12.3 2.2 1.6 1 0 0 1 1 1 0 PHD-finger Nup96 PF12110.8 EMC97775.1 - 2.4e-65 220.5 1.2 4.3e-65 219.7 1.2 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EMC97775.1 - 5.4e-51 172.6 0.0 9.3e-51 171.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase GMC_oxred_N PF00732.19 EMC97776.1 - 7.9e-75 252.0 0.0 1.1e-74 251.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC97776.1 - 4.8e-38 130.9 0.1 1.2e-37 129.6 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EMC97776.1 - 3.8e-05 23.8 0.0 0.00012 22.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMC97776.1 - 0.00028 20.1 0.1 0.0004 19.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EMC97776.1 - 0.00049 19.3 0.2 0.0015 17.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EMC97776.1 - 0.00069 18.9 0.2 0.0016 17.8 0.1 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EMC97776.1 - 0.004 16.8 0.1 0.0085 15.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC97776.1 - 0.0063 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.18 EMC97776.1 - 0.0081 16.4 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 EMC97776.1 - 0.0089 15.3 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC97776.1 - 0.0091 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC97776.1 - 0.025 15.2 0.0 0.067 13.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EMC97776.1 - 0.19 10.6 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase CFEM PF05730.11 EMC97777.1 - 2.6e-07 30.6 9.8 4.7e-07 29.8 9.8 1.5 1 0 0 1 1 1 1 CFEM domain Prenyltrans PF00432.21 EMC97778.1 - 3.1e-29 100.4 23.6 5e-09 35.7 1.0 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat DUF4129 PF13559.6 EMC97779.1 - 0.018 15.3 0.0 0.047 14.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Metallophos PF00149.28 EMC97780.1 - 3.1e-30 106.2 0.0 7.7e-30 104.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EMC97780.1 - 6.9e-13 49.2 1.0 2.5e-12 47.5 1.0 2.1 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EMC97780.1 - 6e-11 42.8 1.2 1.4e-10 41.6 0.3 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EMC97780.1 - 0.057 14.0 0.1 0.56 10.8 0.1 2.3 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Na_Ca_ex PF01699.24 EMC97781.1 - 1.4e-44 151.7 39.5 6.4e-23 81.4 16.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Spc7_C2 PF15577.6 EMC97781.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Spc7_C2 SNARE_assoc PF09335.11 EMC97781.1 - 0.088 13.3 0.1 0.088 13.3 0.1 3.7 3 2 0 3 3 3 0 SNARE associated Golgi protein MerR PF00376.23 EMC97782.1 - 0.08 12.7 0.1 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 MerR family regulatory protein BpuSI_N PF15516.6 EMC97783.1 - 0.15 11.9 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 BpuSI N-terminal domain ABC1 PF03109.16 EMC97784.1 - 4.1e-22 78.6 0.0 9.1e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EMC97784.1 - 0.029 14.3 2.8 0.27 11.1 0.1 2.8 3 1 0 3 3 3 0 Phosphotransferase enzyme family p450 PF00067.22 EMC97785.1 - 4.1e-65 220.3 0.0 5.2e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DFP PF04127.15 EMC97787.1 - 6.6e-14 52.2 0.0 4.5e-05 23.4 0.0 3.2 2 1 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.16 EMC97788.1 - 7.2e-35 120.5 20.6 7.2e-35 120.5 20.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC97788.1 - 2.4e-07 30.0 3.1 2.4e-07 30.0 3.1 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter EI24 PF07264.11 EMC97789.1 - 7.2e-12 45.9 3.6 1.1e-11 45.3 3.6 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ARL6IP6 PF15062.6 EMC97789.1 - 0.19 11.9 0.4 0.35 11.0 0.4 1.4 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Tannase PF07519.11 EMC97790.1 - 8e-112 374.5 2.5 9.7e-112 374.2 2.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EMC97790.1 - 0.0034 16.7 0.0 0.049 12.9 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 CRAL_TRIO PF00650.20 EMC97792.1 - 2.4e-36 124.9 0.0 3e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMC97792.1 - 3.7e-13 49.4 0.1 9.8e-13 48.1 0.1 1.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF3926 PF13080.6 EMC97792.1 - 0.082 12.9 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Pol_alpha_B_N PF08418.10 EMC97793.1 - 1.1e-80 271.2 0.3 1.4e-80 270.8 0.3 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EMC97793.1 - 2.2e-33 115.4 0.1 3.1e-33 114.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Phosducin PF02114.16 EMC97794.1 - 1.4e-10 40.6 0.7 2.3e-06 26.8 0.9 3.0 2 1 0 2 2 2 2 Phosducin adh_short PF00106.25 EMC97796.1 - 2.2e-18 66.4 0.0 8.1e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC97796.1 - 1.6e-07 31.2 0.0 8.7e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC97796.1 - 0.00031 20.7 0.1 0.0005 20.0 0.1 1.3 1 0 0 1 1 1 1 KR domain WD40 PF00400.32 EMC97797.1 - 1.3e-38 130.3 16.7 1.9e-05 25.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC97797.1 - 7e-16 58.3 0.0 0.00034 20.9 0.1 5.0 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMC97797.1 - 6e-05 23.0 0.0 0.041 13.7 0.0 2.8 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EMC97797.1 - 0.00092 18.6 0.0 0.014 14.8 0.0 2.4 1 1 1 2 2 2 1 WD40-like domain Ribosomal_S14 PF00253.21 EMC97799.1 - 1.8e-14 53.2 3.3 2e-14 53.1 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Apc13p PF05839.11 EMC97800.1 - 2e-27 95.2 0.0 2.3e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Apc13p protein GCV_H PF01597.19 EMC97801.1 - 1.5e-43 147.6 0.6 1.9e-43 147.3 0.6 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EMC97801.1 - 0.00029 20.6 1.4 0.0012 18.6 1.0 1.9 1 1 1 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 EMC97801.1 - 0.00067 19.6 0.1 0.00099 19.0 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Ribosomal_S6 PF01250.17 EMC97802.1 - 1.6e-24 86.0 0.0 1.9e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Nup192 PF11894.8 EMC97803.1 - 9.3e-286 951.3 2.9 1.3e-285 950.9 2.9 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 PI3_PI4_kinase PF00454.27 EMC97804.1 - 1.8e-55 188.5 0.0 5.3e-55 186.9 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EMC97804.1 - 7.8e-44 149.5 0.4 5.6e-43 146.7 0.1 2.9 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EMC97804.1 - 6e-10 38.8 0.1 1.9e-09 37.2 0.1 2.0 1 0 0 1 1 1 1 FATC domain IF-2B PF01008.17 EMC97805.1 - 7.4e-76 255.0 0.0 9.2e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF5594 PF18057.1 EMC97805.1 - 0.14 12.0 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5594) Zn_clus PF00172.18 EMC97806.1 - 2.3e-07 30.8 13.9 3.6e-07 30.2 13.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EMC97807.1 - 7.9e-30 103.8 0.0 1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC97807.1 - 1.2e-23 84.0 0.0 1.6e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC97807.1 - 0.00048 20.1 0.1 0.0048 16.8 0.0 2.0 2 0 0 2 2 2 1 KR domain ThiC-associated PF13667.6 EMC97807.1 - 0.04 13.8 0.1 0.086 12.7 0.1 1.6 1 0 0 1 1 1 0 ThiC-associated domain MKT1_C PF12246.8 EMC97808.1 - 1.2e-55 188.4 0.0 1.6e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication ABC_tran PF00005.27 EMC97809.1 - 1.9e-14 54.3 0.3 4.4e-13 49.9 0.3 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMC97809.1 - 3.7e-11 43.4 2.7 7.4e-05 22.7 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMC97809.1 - 0.0018 18.0 0.4 0.0042 16.8 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 EMC97809.1 - 0.0023 15.6 0.2 0.0029 15.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.6 EMC97809.1 - 0.0076 16.8 0.2 0.011 16.2 0.2 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EMC97809.1 - 0.0092 15.4 0.0 3.1 7.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 EMC97809.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EMC97809.1 - 0.019 14.5 0.2 0.036 13.6 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EMC97809.1 - 0.026 14.3 0.1 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EMC97809.1 - 0.026 14.4 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 EMC97809.1 - 0.028 14.7 0.6 0.059 13.6 0.6 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMC97809.1 - 0.068 13.6 1.9 0.23 11.8 1.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 EMC97809.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EMC97809.1 - 0.15 12.3 1.3 0.6 10.4 1.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EMC97809.1 - 0.2 10.2 0.3 0.28 9.8 0.3 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EMC97809.1 - 0.23 11.9 0.2 1.1 9.6 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IPPT PF01715.17 EMC97810.1 - 5.6e-64 216.1 0.1 8.1e-64 215.6 0.1 1.2 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 EMC97810.1 - 1.7e-07 31.5 0.1 5.5e-06 26.6 0.1 2.8 1 1 0 1 1 1 1 AAA domain IPT PF01745.16 EMC97810.1 - 1.8e-05 24.3 0.0 4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_18 PF13238.6 EMC97810.1 - 2.4e-05 24.9 2.0 0.0048 17.4 0.1 3.0 3 0 0 3 3 3 1 AAA domain zf-met PF12874.7 EMC97810.1 - 0.00018 21.8 1.9 0.00036 20.8 1.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMC97810.1 - 0.00026 21.2 2.6 0.00053 20.2 2.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_16 PF13191.6 EMC97810.1 - 0.0039 17.6 0.2 0.022 15.1 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EMC97810.1 - 0.0078 16.5 2.3 0.038 14.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EMC97810.1 - 0.03 14.6 0.1 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EMC97810.1 - 0.047 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin PF02224.18 EMC97810.1 - 0.07 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase Hpr_kinase_C PF07475.12 EMC97810.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain IstB_IS21 PF01695.17 EMC97810.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF87 PF01935.17 EMC97810.1 - 0.093 12.8 0.7 0.62 10.1 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain zf-C2H2_2 PF12756.7 EMC97810.1 - 0.11 12.8 0.8 0.21 12.0 0.8 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) NTP_transf_9 PF04248.12 EMC97811.1 - 4.1e-30 103.5 1.1 4.7e-30 103.3 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) RAMP PF04901.13 EMC97811.1 - 0.00038 20.4 0.3 0.00047 20.1 0.3 1.1 1 0 0 1 1 1 1 Receptor activity modifying family Peptidase_M16_C PF05193.21 EMC97813.1 - 1.1e-45 156.0 0.0 2.4e-44 151.6 0.0 2.6 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EMC97813.1 - 1e-39 135.9 0.0 1.7e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FHA PF00498.26 EMC97814.1 - 9.1e-16 58.0 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EMC97814.1 - 5.7e-14 51.6 4.6 1.3e-13 50.5 4.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EMC97814.1 - 2e-09 37.6 8.4 4.4e-09 36.5 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EMC97814.1 - 4.8e-05 23.2 6.0 8.5e-05 22.4 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EMC97814.1 - 8.4e-05 22.4 7.7 0.00015 21.5 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC97814.1 - 0.0003 20.6 8.5 0.00062 19.6 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EMC97814.1 - 0.00056 19.9 1.7 0.001 19.1 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Yop-YscD_cpl PF16697.5 EMC97814.1 - 0.00082 19.6 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-rbx1 PF12678.7 EMC97814.1 - 0.00088 19.5 5.3 0.0022 18.2 5.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Vps39_2 PF10367.9 EMC97814.1 - 0.0024 18.3 0.2 0.0037 17.7 0.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 EMC97814.1 - 0.0029 17.6 6.3 0.0058 16.6 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING-like PF08746.11 EMC97814.1 - 0.012 15.9 5.4 0.027 14.8 5.4 1.6 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 EMC97814.1 - 0.02 14.5 5.4 0.043 13.4 5.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EMC97814.1 - 0.039 13.9 5.4 0.09 12.7 5.4 1.7 1 0 0 1 1 1 0 PHD-finger GTP_EFTU PF00009.27 EMC97816.1 - 6.3e-35 120.5 0.0 1.2e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EMC97816.1 - 4.2e-14 52.3 0.0 2.1e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EMC97816.1 - 5.9e-10 39.4 0.0 2.1e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EMC97816.1 - 1.6e-07 31.3 0.0 3.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EMC97816.1 - 0.0057 16.4 0.0 0.032 14.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor G, domain IV PH PF00169.29 EMC97817.1 - 1.6e-28 99.3 0.4 2.7e-13 50.3 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EMC97817.1 - 6.3e-09 36.2 2.2 0.0042 17.5 0.1 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 EMC97817.1 - 9.4e-08 32.4 2.5 0.0023 18.3 0.6 3.7 2 2 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 EMC97817.1 - 2.4e-06 27.8 0.3 1e-05 25.7 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 EMC97817.1 - 0.0005 20.1 0.4 0.047 13.8 0.1 2.6 2 1 0 2 2 2 1 PH domain PH_2 PF08458.10 EMC97817.1 - 0.0092 16.3 0.3 0.053 13.9 0.0 2.3 2 2 0 2 2 2 1 Plant pleckstrin homology-like region Mcp5_PH PF12814.7 EMC97817.1 - 0.075 13.1 0.9 5.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_13 PF16652.5 EMC97817.1 - 0.11 12.3 0.2 0.33 10.7 0.1 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain MDM10 PF12519.8 EMC97818.1 - 1.4e-140 469.2 2.3 3.4e-127 425.2 0.7 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EMC97818.1 - 2.4e-05 23.9 0.2 0.53 9.7 0.0 3.2 3 1 1 4 4 4 2 Eukaryotic porin AMP-binding PF00501.28 EMC97819.1 - 5.7e-77 259.1 0.0 7.1e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC97819.1 - 1e-16 61.7 0.1 3.6e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Kinesin PF00225.23 EMC97820.1 - 7.9e-112 373.5 0.7 1.1e-111 373.0 0.7 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMC97820.1 - 9.3e-27 93.8 0.0 2e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding ZapB PF06005.12 EMC97820.1 - 0.00051 20.4 0.2 0.11 13.0 0.0 3.0 1 1 1 2 2 2 1 Cell division protein ZapB SKA2 PF16740.5 EMC97820.1 - 0.027 14.2 3.2 0.068 13.0 3.2 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Shugoshin_N PF07558.11 EMC97820.1 - 0.098 12.5 1.1 0.2 11.5 0.3 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TPR_MLP1_2 PF07926.12 EMC97820.1 - 0.18 11.8 13.7 0.5 10.4 13.7 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4763 PF15960.5 EMC97820.1 - 0.35 10.1 6.6 0.75 9.1 6.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Phage_Mu_Gam PF07352.12 EMC97820.1 - 0.53 10.2 5.7 13 5.6 1.8 2.9 1 1 0 2 2 2 0 Bacteriophage Mu Gam like protein PAPS_reduct PF01507.19 EMC97820.1 - 0.57 10.2 2.7 6.6 6.7 1.5 2.3 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family YabA PF06156.13 EMC97820.1 - 0.63 10.7 9.4 8.6 7.1 0.9 3.6 3 1 1 4 4 4 0 Initiation control protein YabA DUF2730 PF10805.8 EMC97820.1 - 2.2 8.4 5.0 3.8 7.7 3.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF87 PF01935.17 EMC97820.1 - 2.7 8.0 8.3 0.66 10.0 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain MFS_1 PF07690.16 EMC97821.1 - 1.3e-46 159.2 49.9 8.4e-46 156.5 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC97821.1 - 5.5e-05 22.2 9.4 5.5e-05 22.2 9.4 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter SpoU_methylase PF00588.19 EMC97822.1 - 1.7e-26 93.1 0.0 2.9e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family Olduvai PF06758.13 EMC97823.1 - 2.7 8.3 6.2 0.26 11.6 0.6 2.2 3 0 0 3 3 3 0 Olduvai domain WD40 PF00400.32 EMC97825.1 - 3.3e-40 135.3 20.8 6.5e-06 26.8 0.4 8.0 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EMC97825.1 - 1.2e-10 41.1 0.1 2.4e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC97825.1 - 8.1e-07 28.8 0.1 1.9e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EMC97825.1 - 2.3e-06 27.8 0.2 2 8.8 0.0 4.3 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EMC97825.1 - 0.0017 18.0 1.6 0.028 14.0 1.3 2.6 1 1 0 1 1 1 1 PQQ-like domain F-box_4 PF15966.5 EMC97825.1 - 0.022 14.7 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 F-box PQQ_3 PF13570.6 EMC97825.1 - 0.14 12.7 0.1 1.2e+02 3.3 0.0 4.0 3 0 0 3 3 3 0 PQQ-like domain Nup160 PF11715.8 EMC97825.1 - 0.31 9.6 8.6 3.1 6.3 0.3 4.1 3 2 2 5 5 5 0 Nucleoporin Nup120/160 LRR_6 PF13516.6 EMC97826.1 - 0.02 14.9 0.8 0.78 9.9 0.1 2.7 2 0 0 2 2 2 0 Leucine Rich repeat DUF3425 PF11905.8 EMC97827.1 - 3.4e-18 65.8 0.2 7.6e-18 64.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EMC97827.1 - 0.0055 16.8 5.8 0.033 14.3 6.3 2.0 2 0 0 2 2 2 1 bZIP transcription factor PKcGMP_CC PF16808.5 EMC97827.1 - 7.5 6.5 8.3 6.3 6.7 1.0 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Hexapep PF00132.24 EMC97828.1 - 6.8e-10 38.3 13.3 0.0066 16.1 1.8 5.0 4 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMC97828.1 - 4.3 7.2 13.7 5.9 6.7 1.2 3.7 1 1 3 4 4 4 0 Hexapeptide repeat of succinyl-transferase DUF1295 PF06966.12 EMC97831.1 - 1.2e-43 149.3 0.2 5.2e-42 144.0 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EMC97831.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EMC97831.1 - 0.073 13.5 0.0 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Amino_oxidase PF01593.24 EMC97833.1 - 3.8e-57 194.6 0.0 2.3e-55 188.7 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMC97833.1 - 2.1e-06 27.9 0.0 5.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMC97833.1 - 0.035 13.4 0.1 0.62 9.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SYCP2_ARLD PF18581.1 EMC97834.1 - 0.092 12.7 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain Glyco_hydro_16 PF00722.21 EMC97835.1 - 1e-14 54.4 0.5 1.8e-14 53.6 0.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 GTP_EFTU PF00009.27 EMC97836.1 - 3.2e-58 196.5 0.2 4.3e-58 196.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMC97836.1 - 3.8e-27 94.8 0.0 8.4e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMC97836.1 - 2.1e-17 63.3 0.9 2.1e-17 63.3 0.9 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMC97836.1 - 1.4e-05 25.2 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EMC97836.1 - 0.0021 17.8 0.2 1.3 8.7 0.1 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EMC97836.1 - 0.0085 16.0 0.3 0.057 13.3 0.1 2.1 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 EMC97836.1 - 0.017 14.7 0.4 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ECH_2 PF16113.5 EMC97837.1 - 7.1e-122 407.1 0.0 8.8e-122 406.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EMC97837.1 - 5.8e-27 94.6 0.0 1.7e-26 93.1 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase RNA_pol_Rpc4 PF05132.14 EMC97838.1 - 2.9e-30 105.6 0.3 9.4e-30 104.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase III RPC4 Fringe PF02434.16 EMC97839.1 - 2.7e-08 33.6 0.4 2.4e-07 30.5 0.4 2.0 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 EMC97839.1 - 0.0014 18.5 1.3 0.0041 17.0 1.3 1.8 1 0 0 1 1 1 1 PAN domain Ribosomal_L32e PF01655.18 EMC97842.1 - 4.5e-52 175.0 0.9 6.3e-52 174.6 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 RL10P_insert PF17777.1 EMC97843.1 - 2e-22 79.0 0.0 4.3e-22 77.9 0.0 1.6 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EMC97843.1 - 2.6e-16 59.6 0.0 4e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 SGL PF08450.12 EMC97846.1 - 2.4e-24 86.2 0.1 4.8e-24 85.3 0.1 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EMC97846.1 - 9e-06 25.8 0.1 2.8e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.16 EMC97846.1 - 0.00078 19.5 0.0 0.0039 17.3 0.0 2.2 1 1 0 1 1 1 1 Strictosidine synthase Sugar_tr PF00083.24 EMC97848.1 - 8.1e-09 34.8 0.6 9e-09 34.7 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter ADH_zinc_N_2 PF13602.6 EMC97851.1 - 2.4e-24 86.9 0.0 4.2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMC97851.1 - 1.5e-13 50.8 0.1 2.8e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMC97851.1 - 9e-06 25.6 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ArAE_2_N PF10337.9 EMC97852.1 - 9.9e-46 156.7 26.4 2.1e-38 132.6 3.1 4.2 3 1 1 4 4 4 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EMC97852.1 - 1.2e-14 54.6 14.6 1.2e-14 54.6 14.6 3.4 2 2 2 4 4 4 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EMC97852.1 - 2.5e-13 50.4 0.0 1.5e-12 47.8 0.0 2.2 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 Asp PF00026.23 EMC97853.1 - 9.4e-70 235.5 8.4 1.1e-69 235.3 8.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMC97853.1 - 3.1e-11 43.8 4.5 2.5e-10 40.9 1.3 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMC97853.1 - 5.4e-05 23.8 5.7 0.12 13.1 0.1 3.4 3 1 0 3 3 3 2 Aspartyl protease adh_short PF00106.25 EMC97854.1 - 2.1e-08 33.9 0.2 0.019 14.4 0.1 3.5 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 EMC97854.1 - 0.00023 20.8 0.0 0.36 10.4 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC97854.1 - 0.085 12.8 0.4 0.25 11.2 0.2 1.9 2 0 0 2 2 2 0 KR domain BtpA PF03437.15 EMC97854.1 - 0.12 11.7 0.0 0.48 9.8 0.5 1.6 2 0 0 2 2 2 0 BtpA family Alb1 PF09135.11 EMC97855.1 - 2.2e-18 67.1 8.0 4.4e-18 66.1 8.0 1.4 1 0 0 1 1 1 1 Alb1 L31 PF09784.9 EMC97855.1 - 0.079 13.4 4.2 0.13 12.7 4.2 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 PIEZO PF15917.5 EMC97855.1 - 0.77 9.2 5.3 1.2 8.5 5.3 1.3 1 0 0 1 1 1 0 Piezo DivIC PF04977.15 EMC97855.1 - 1.2 9.0 5.8 1.7 8.5 4.0 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF4337 PF14235.6 EMC97855.1 - 8.8 6.4 7.4 13 5.9 7.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) UCH PF00443.29 EMC97856.1 - 1.1e-34 120.1 0.0 2.4e-34 119.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC97856.1 - 1.1e-07 31.7 3.0 2.9e-07 30.4 1.6 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ELP6 PF09807.9 EMC97857.1 - 2.7e-05 23.7 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Elongation complex protein 6 FliC PF12445.8 EMC97857.1 - 0.13 12.6 2.4 0.61 10.4 2.7 2.1 1 1 1 2 2 2 0 Flagellin protein ZoocinA_TRD PF16775.5 EMC97857.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme Git3 PF11710.8 EMC97858.1 - 9.6e-22 77.8 9.8 3.9e-21 75.8 9.8 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EMC97858.1 - 1.4e-08 34.6 0.2 6.9e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EMC97858.1 - 0.00012 21.5 4.0 0.00012 21.5 4.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF996 PF06195.13 EMC97858.1 - 3.6 7.9 9.7 1.8 8.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF996) Dicty_CAR PF05462.11 EMC97858.1 - 9 5.3 13.1 4.6 6.3 10.4 1.9 2 1 0 2 2 2 0 Slime mold cyclic AMP receptor RdRP PF05183.12 EMC97859.1 - 6.7e-181 602.9 0.0 8.5e-181 602.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase ATG16 PF08614.11 EMC97860.1 - 0.0001 22.6 39.9 0.087 13.0 4.6 3.3 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EMC97860.1 - 0.0056 16.2 34.0 0.011 15.3 14.6 2.3 1 1 1 2 2 2 1 Golgin subfamily A member 5 MscS_porin PF12795.7 EMC97860.1 - 0.0059 16.2 31.5 0.013 15.1 12.9 3.3 2 1 1 3 3 3 2 Mechanosensitive ion channel porin domain BST2 PF16716.5 EMC97860.1 - 0.013 16.0 7.5 0.013 16.0 7.5 3.9 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 EMC97860.1 - 0.013 14.4 34.8 0.027 13.3 4.4 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Rab_bind PF16704.5 EMC97860.1 - 0.031 14.3 0.4 0.25 11.4 0.1 2.5 2 0 0 2 2 2 0 Rab binding domain APG6_N PF17675.1 EMC97860.1 - 0.072 13.6 42.9 0.5 10.9 15.1 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region EzrA PF06160.12 EMC97860.1 - 0.074 11.2 18.4 0.065 11.4 1.2 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Myosin_tail_1 PF01576.19 EMC97860.1 - 0.26 9.0 37.6 0.056 11.2 5.7 2.5 1 1 0 2 2 2 0 Myosin tail Filament PF00038.21 EMC97860.1 - 0.42 10.1 34.2 0.6 9.6 24.8 2.8 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.11 EMC97860.1 - 0.53 10.7 3.7 2.7 8.4 0.0 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.6 EMC97860.1 - 0.69 8.5 26.9 0.068 11.8 6.8 2.1 1 1 1 2 2 2 0 AAA domain DUF1664 PF07889.12 EMC97860.1 - 1.1 9.3 15.2 0.32 11.0 0.2 3.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 EMC97860.1 - 1.9 8.2 22.5 0.024 14.3 2.4 3.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF724 PF05266.14 EMC97860.1 - 3.7 7.3 28.1 1.7 8.5 1.3 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF3510 PF12022.8 EMC97860.1 - 3.8 7.9 7.9 6.3 7.2 2.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) DUF948 PF06103.11 EMC97860.1 - 4.9 7.5 6.8 17 5.8 0.2 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4795 PF16043.5 EMC97860.1 - 5.1 6.6 29.8 0.69 9.5 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 EMC97860.1 - 5.6 7.2 20.9 5.8 7.1 5.4 3.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family RasGAP_C PF03836.15 EMC97860.1 - 6.3 7.0 10.8 0.33 11.1 0.5 2.9 2 1 0 2 2 2 0 RasGAP C-terminus Seryl_tRNA_N PF02403.22 EMC97860.1 - 9 6.6 25.5 0.6 10.4 0.2 4.3 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.8 EMC97860.1 - 9 6.4 37.9 8.5 6.4 16.3 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TolA_bind_tri PF16331.5 EMC97860.1 - 9.8 6.3 23.8 1.4 9.0 0.9 4.6 3 2 1 4 4 4 0 TolA binding protein trimerisation FAD-oxidase_C PF02913.19 EMC97861.1 - 3.3e-67 226.8 0.2 4.5e-67 226.3 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMC97861.1 - 1.3e-33 115.7 0.0 2.1e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 EMC97861.1 - 0.14 10.8 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Helo_like_N PF17111.5 EMC97862.1 - 1.2e-05 24.7 0.2 1.9e-05 24.1 0.2 1.4 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF4503 PF14951.6 EMC97862.1 - 0.0017 16.9 0.0 0.0021 16.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) DUF3247 PF11607.8 EMC97862.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3247) PHBC_N PF12551.8 EMC97862.1 - 0.14 12.0 0.3 0.24 11.2 0.3 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal ISG65-75 PF11727.8 EMC97862.1 - 0.17 11.1 1.0 0.19 10.9 1.0 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein YyzF PF14116.6 EMC97862.1 - 0.22 11.6 0.2 25 5.0 0.0 2.3 2 0 0 2 2 2 0 YyzF-like protein Methyltransf_2 PF00891.18 EMC97863.1 - 3e-23 82.2 0.0 5.4e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Pilus_CpaD PF09476.10 EMC97863.1 - 0.063 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Semialdhyde_dhC PF02774.18 EMC97864.1 - 4.6e-38 131.1 0.0 6.6e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EMC97864.1 - 2.6e-29 102.1 0.0 4.8e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EMC97864.1 - 0.03 14.6 0.0 0.089 13.1 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_C PF02800.20 EMC97864.1 - 0.17 11.5 0.1 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Hydrolase_6 PF13344.6 EMC97865.1 - 1.3e-22 79.7 0.0 3.6e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC97865.1 - 6.1e-20 71.1 0.0 2.3e-19 69.2 0.0 2.0 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 EMC97865.1 - 2.4e-05 24.7 0.0 0.15 12.3 0.0 3.2 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMC97865.1 - 0.029 14.4 0.0 4.7 7.3 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMC97865.1 - 0.22 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Bac_rhodopsin PF01036.18 EMC97866.1 - 6.3e-63 212.3 13.9 8e-63 212.0 13.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Amino_oxidase PF01593.24 EMC97867.1 - 3.4e-22 79.4 0.0 1.5e-20 74.0 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMC97867.1 - 5e-13 49.1 0.1 1.3e-12 47.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC97867.1 - 1.3e-11 44.7 0.3 3.4e-10 40.0 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC97867.1 - 2.6e-10 40.0 0.0 8.4e-07 28.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC97867.1 - 1.8e-06 27.3 1.9 1.3e-05 24.5 1.4 2.3 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 EMC97867.1 - 1.3e-05 24.8 0.0 9.6e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC97867.1 - 3.4e-05 22.7 0.1 0.00065 18.5 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EMC97867.1 - 0.00098 18.4 0.2 0.0018 17.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family GMC_oxred_N PF00732.19 EMC97867.1 - 0.0023 17.4 0.2 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 EMC97867.1 - 0.0024 17.2 0.4 0.0046 16.2 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMC97867.1 - 0.0026 16.9 0.6 0.0041 16.2 0.6 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EMC97867.1 - 0.0042 17.6 2.9 0.53 10.9 0.6 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC97867.1 - 0.0043 16.4 0.3 0.0085 15.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 EMC97867.1 - 0.007 15.2 0.0 2.1 7.0 0.0 2.2 2 0 0 2 2 2 2 MCRA family Lycopene_cycl PF05834.12 EMC97867.1 - 0.027 13.5 0.2 0.12 11.4 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.18 EMC97867.1 - 0.035 12.6 0.0 0.35 9.3 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_binding_7 PF13241.6 EMC97867.1 - 0.077 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EMC97867.1 - 0.15 12.1 0.2 0.38 10.7 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EMC97867.1 - 0.17 11.8 0.6 0.3 10.9 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SQS_PSY PF00494.19 EMC97868.1 - 4.6e-58 196.8 0.1 6e-58 196.4 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.15 EMC97869.1 - 8.6e-124 414.2 0.0 1.1e-123 413.9 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SLAC1 PF03595.17 EMC97870.1 - 1.1e-85 287.7 57.7 1.3e-85 287.5 57.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Cyclin_N PF00134.23 EMC97871.1 - 6.2e-13 48.6 0.0 1.2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EMC97871.1 - 8.6e-09 36.0 0.0 1.3e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin RA PF00788.23 EMC97873.1 - 2.5e-11 44.1 0.0 6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 EMC97873.1 - 2.9e-10 40.4 0.0 6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EMC97873.1 - 1.1e-08 35.1 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GST_C_2 PF13410.6 EMC97873.1 - 6e-05 23.0 0.1 0.00019 21.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC97873.1 - 0.074 13.3 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SAM_PNT PF02198.16 EMC97873.1 - 0.083 12.9 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_4 PF18017.1 EMC97873.1 - 0.23 11.5 0.0 0.61 10.1 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA PF00004.29 EMC97874.1 - 2.8e-96 319.0 0.0 9.3e-47 158.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMC97874.1 - 2.6e-25 87.9 3.6 2.2e-13 49.8 0.3 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EMC97874.1 - 2.7e-20 72.3 0.4 8.2e-20 70.8 0.4 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EMC97874.1 - 1.3e-13 51.4 0.0 1.7e-07 31.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EMC97874.1 - 2.1e-13 50.3 0.0 2.8e-05 23.9 0.0 3.3 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EMC97874.1 - 1.5e-12 47.9 0.0 7.6e-06 26.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMC97874.1 - 2.1e-11 44.5 0.0 0.00015 22.2 0.0 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EMC97874.1 - 1.5e-10 41.2 0.4 3.3e-05 23.9 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EMC97874.1 - 6e-09 35.6 0.0 0.0018 17.6 0.0 2.8 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EMC97874.1 - 6.5e-09 36.2 0.3 0.06 13.6 0.1 4.1 2 2 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EMC97874.1 - 2.4e-07 30.4 0.3 0.036 13.4 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EMC97874.1 - 4e-07 29.9 0.0 0.026 14.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein CDC48_2 PF02933.17 EMC97874.1 - 1e-06 28.4 0.0 2.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 EMC97874.1 - 1.5e-06 28.8 0.0 0.055 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EMC97874.1 - 2.2e-06 28.0 0.0 0.032 14.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 EMC97874.1 - 2.3e-06 27.1 0.5 0.43 9.9 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_14 PF13173.6 EMC97874.1 - 3.7e-06 27.0 0.0 0.021 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EMC97874.1 - 9.7e-06 25.2 0.1 0.051 13.1 0.0 3.0 2 2 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 EMC97874.1 - 1.5e-05 24.9 0.1 5.4e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 EMC97874.1 - 2.7e-05 23.8 5.0 0.62 9.6 0.1 4.7 3 2 1 5 5 5 1 AAA domain AAA_28 PF13521.6 EMC97874.1 - 4.1e-05 23.9 0.0 0.31 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EMC97874.1 - 6.9e-05 22.6 0.1 0.63 9.7 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 EMC97874.1 - 7.4e-05 22.0 0.0 0.022 13.9 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EMC97874.1 - 9.4e-05 22.2 0.0 0.71 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 EMC97874.1 - 0.0001 21.5 0.1 0.099 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 EMC97874.1 - 0.0001 21.8 0.4 0.45 9.9 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 EMC97874.1 - 0.00016 22.2 0.0 0.43 11.1 0.0 3.4 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.6 EMC97874.1 - 0.00016 22.1 0.2 0.85 10.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain Bac_DnaA PF00308.18 EMC97874.1 - 0.00016 21.6 0.0 0.96 9.2 0.0 3.2 3 0 0 3 3 3 2 Bacterial dnaA protein ResIII PF04851.15 EMC97874.1 - 0.00069 19.7 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 EMC97874.1 - 0.00078 19.4 0.0 0.78 9.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EMC97874.1 - 0.00096 19.0 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EMC97874.1 - 0.0012 18.7 0.4 1.3 8.7 0.0 2.6 3 0 0 3 3 2 2 AAA domain DUF2075 PF09848.9 EMC97874.1 - 0.002 17.4 0.0 0.91 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EMC97874.1 - 0.0028 17.4 0.4 2.1 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain UFD1 PF03152.14 EMC97874.1 - 0.0044 16.5 0.0 0.048 13.1 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 Viral_helicase1 PF01443.18 EMC97874.1 - 0.0062 16.3 0.0 0.67 9.6 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EMC97874.1 - 0.0066 16.8 0.5 9.1 6.6 0.0 3.4 3 1 0 4 4 2 0 AAA domain ATPase_2 PF01637.18 EMC97874.1 - 0.0068 16.4 0.0 12 5.7 0.0 3.5 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EMC97874.1 - 0.0068 16.3 0.1 1.3 8.9 0.0 2.8 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.12 EMC97874.1 - 0.02 14.2 0.4 6.3 6.0 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin KAP_NTPase PF07693.14 EMC97874.1 - 0.022 14.0 0.0 0.93 8.7 0.0 2.6 2 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 EMC97874.1 - 0.026 14.7 0.0 4 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EMC97874.1 - 0.029 14.3 0.4 4.1 7.3 0.0 3.4 3 0 0 3 3 3 0 NTPase IPT PF01745.16 EMC97874.1 - 0.031 13.7 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.22 EMC97874.1 - 0.032 13.4 0.0 2 7.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain eIF-1a PF01176.19 EMC97874.1 - 0.076 12.8 0.9 0.44 10.4 0.4 2.4 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 AAA_6 PF12774.7 EMC97874.1 - 0.1 11.5 0.0 11 4.9 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin2 PF13189.6 EMC97874.1 - 0.11 12.6 0.0 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family Zot PF05707.12 EMC97874.1 - 0.17 11.5 0.0 9 5.9 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) cobW PF02492.19 EMC97875.1 - 7.9e-24 84.2 5.0 6.8e-16 58.4 0.2 3.1 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EMC97875.1 - 0.00084 18.4 1.1 0.022 13.8 0.0 2.8 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CobW_C PF07683.14 EMC97875.1 - 0.0057 16.6 0.2 0.82 9.6 0.1 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain Glyco_hydro_31 PF01055.26 EMC97876.1 - 4.1e-159 530.5 4.0 5.4e-159 530.1 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EMC97876.1 - 7e-41 139.1 0.1 1.6e-40 137.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CBM_20 PF00686.19 EMC97876.1 - 7e-16 57.9 0.1 7e-16 57.9 0.1 1.9 2 0 0 2 2 2 1 Starch binding domain Gal_mutarotas_2 PF13802.6 EMC97876.1 - 6.8e-14 51.9 1.6 2.8e-13 50.0 1.6 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Lactonase PF10282.9 EMC97877.1 - 1.2e-79 268.1 0.0 1.4e-79 267.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HCV_NS4a PF01006.20 EMC97877.1 - 0.077 12.8 0.0 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a zinc_ribbon_5 PF13719.6 EMC97877.1 - 0.13 12.0 0.3 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain KRE9 PF05390.11 EMC97877.1 - 7.7 7.3 7.4 21 5.9 0.1 2.7 3 0 0 3 3 3 0 Yeast cell wall synthesis protein KRE9/KNH1 adh_short PF00106.25 EMC97878.1 - 4.4e-41 140.5 0.0 6.9e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC97878.1 - 3.7e-31 108.5 0.4 4.7e-31 108.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC97878.1 - 1.6e-09 37.9 0.1 3.2e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC97878.1 - 4.3e-05 23.1 0.5 0.00029 20.4 0.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMC97878.1 - 0.0041 16.5 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 EMC97878.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 EMC97878.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family SIP1 PF04938.12 EMC97879.1 - 3.3e-10 40.0 0.0 4.4e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Peptidase_M20 PF01546.28 EMC97880.1 - 1.9e-20 73.4 0.0 5.3e-20 72.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMC97880.1 - 2.1e-14 53.4 0.1 8.9e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain UPF0231 PF06062.11 EMC97880.1 - 0.07 13.4 0.0 0.21 11.9 0.0 1.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) MIP PF00230.20 EMC97881.1 - 9.9e-48 162.8 17.6 1.1e-47 162.6 17.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein zf-RING_2 PF13639.6 EMC97883.1 - 1e-12 48.2 5.3 1.7e-12 47.4 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMC97883.1 - 2.3e-09 37.0 3.9 3.8e-09 36.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC97883.1 - 1.2e-08 34.6 3.1 2.1e-08 33.9 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMC97883.1 - 1.5e-08 34.8 3.4 3.1e-08 33.8 3.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EMC97883.1 - 3.4e-08 33.1 2.2 3.4e-08 33.1 2.2 2.0 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 EMC97883.1 - 2.4e-07 30.7 0.0 6.9e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 EMC97883.1 - 5.9e-07 29.4 2.4 9.4e-07 28.7 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EMC97883.1 - 5.6e-06 26.3 1.7 5.2e-05 23.2 2.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EMC97883.1 - 7e-06 25.8 3.1 1.1e-05 25.2 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EMC97883.1 - 0.00066 19.7 0.4 0.0013 18.7 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EMC97883.1 - 0.006 16.4 2.6 0.01 15.7 2.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EMC97883.1 - 0.021 14.5 2.7 0.039 13.6 2.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type GT87 PF09594.10 EMC97883.1 - 0.031 14.0 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 87 zf-C3HC4_4 PF15227.6 EMC97883.1 - 0.099 12.8 4.0 0.22 11.7 4.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EMC97883.1 - 0.14 12.4 2.4 0.4 10.9 2.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EMC97883.1 - 0.26 11.4 3.0 0.52 10.5 2.8 1.6 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 EMC97883.1 - 0.87 9.5 2.4 1.9 8.4 2.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 EMC97883.1 - 1.1 9.3 2.4 1.9 8.4 2.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EMC97883.1 - 1.2 9.4 3.2 2.2 8.7 3.2 1.4 1 0 0 1 1 1 0 RING-like domain ANTH PF07651.16 EMC97884.1 - 1.9e-78 263.3 0.0 1.9e-78 263.3 0.0 3.4 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.17 EMC97884.1 - 1.9e-56 190.6 7.9 1.9e-56 190.6 7.9 6.2 4 2 0 6 6 6 2 I/LWEQ domain ENTH PF01417.20 EMC97884.1 - 0.028 14.5 0.1 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 ENTH domain TcdB_N PF12918.7 EMC97884.1 - 0.073 13.4 5.6 0.33 11.3 1.3 3.8 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Ribosomal_S4e PF00900.20 EMC97885.1 - 1.3e-36 124.3 0.1 2.6e-36 123.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EMC97885.1 - 5.9e-24 83.5 0.0 9.9e-24 82.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EMC97885.1 - 2.4e-16 59.5 2.1 4.5e-16 58.7 2.1 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EMC97885.1 - 3.9e-08 32.9 0.0 7.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EMC97885.1 - 0.0018 18.2 1.1 0.0018 18.2 1.1 3.4 4 0 0 4 4 4 1 KOW motif Mito_carr PF00153.27 EMC97886.1 - 1.4e-17 63.4 3.1 7e-12 45.1 0.1 3.3 3 2 0 3 3 3 2 Mitochondrial carrier protein SPT16 PF08644.11 EMC97887.1 - 2.3e-55 186.9 0.1 2.3e-55 186.9 0.1 3.0 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EMC97887.1 - 3.7e-55 186.1 0.4 1.4e-54 184.3 0.4 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EMC97887.1 - 1.1e-28 100.3 0.0 1.8e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EMC97887.1 - 1.5e-16 60.6 0.2 6.6e-16 58.5 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF4291 PF14124.6 EMC97889.1 - 2.1e-62 210.2 1.4 4.1e-62 209.2 1.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4291) U1snRNP70_N PF12220.8 EMC97891.1 - 3.6e-24 85.2 1.6 3.6e-24 85.2 1.6 1.5 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EMC97891.1 - 2.5e-14 52.8 0.1 6.2e-06 26.0 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC97891.1 - 6.9e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 EMC97892.1 - 8.6e-15 54.4 0.1 1.7e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ebp2 PF05890.12 EMC97894.1 - 4.8e-91 305.0 14.2 4.8e-91 305.0 14.2 2.2 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DHHC PF01529.20 EMC97895.1 - 3.4e-38 130.8 3.4 5.8e-38 130.0 3.4 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.7 EMC97895.1 - 0.48 10.5 7.4 1 9.5 7.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_S24 PF00717.23 EMC97896.1 - 3.7e-07 30.0 0.0 5.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EMC97896.1 - 0.00087 19.1 0.0 0.011 15.5 0.0 2.2 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 FAD_binding_3 PF01494.19 EMC97897.1 - 8.2e-12 45.0 0.1 0.0018 17.6 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EMC97897.1 - 0.00018 21.6 0.1 0.00043 20.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC97897.1 - 0.00054 19.3 0.0 0.11 11.7 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC97897.1 - 0.0023 17.6 0.2 0.0037 16.9 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMC97897.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EMC97897.1 - 0.25 10.5 0.0 0.58 9.4 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 EMC97900.1 - 1.6e-38 132.1 0.0 2e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC97900.1 - 3.2e-25 89.0 0.1 1.3e-24 87.1 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC97900.1 - 3.1e-15 56.6 0.1 4.2e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMC97900.1 - 1.2e-08 34.5 0.0 1.6e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMC97900.1 - 9.1e-05 22.0 0.0 0.00026 20.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMC97900.1 - 0.004 16.2 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMC97900.1 - 0.01 15.2 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EMC97900.1 - 0.054 13.6 0.1 0.096 12.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 EMC97900.1 - 0.062 12.4 0.1 0.099 11.7 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 EMC97900.1 - 0.091 12.6 0.4 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Cullin_binding PF03556.15 EMC97902.1 - 1.1e-32 113.0 8.2 1.9e-32 112.2 8.2 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EMC97902.1 - 7.1e-11 41.8 0.4 1.3e-10 40.9 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain DUF2280 PF10045.9 EMC97902.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) TAP_C PF03943.13 EMC97902.1 - 0.032 13.9 0.2 0.07 12.8 0.2 1.6 1 0 0 1 1 1 0 TAP C-terminal domain DUF4996 PF16387.5 EMC97902.1 - 0.074 13.5 2.4 0.095 13.2 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DNA_pol_B PF00136.21 EMC97903.1 - 9.4e-143 476.2 1.2 1.5e-142 475.6 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EMC97903.1 - 7e-83 278.5 0.0 1.1e-82 277.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EMC97903.1 - 1.2e-17 64.2 2.2 3e-17 62.8 2.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 EMC97903.1 - 0.0025 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 EMC97903.1 - 0.0031 16.5 0.5 0.0082 15.0 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EMC97903.1 - 0.03 14.3 0.3 0.25 11.3 0.3 2.4 1 1 0 1 1 1 0 RNase_H superfamily Homeodomain PF00046.29 EMC97904.1 - 4.4e-19 68.1 2.2 1e-18 66.9 2.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EMC97904.1 - 0.041 13.8 0.3 0.092 12.7 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain MAPEG PF01124.18 EMC97905.1 - 2.9e-20 72.5 1.8 3.2e-20 72.3 1.8 1.0 1 0 0 1 1 1 1 MAPEG family UBM PF14377.6 EMC97908.1 - 4.9 6.8 5.2 8.2 6.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin binding region Sulfotransfer_4 PF17784.1 EMC97909.1 - 4.7e-35 121.4 0.1 5.7e-35 121.1 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Adaptin_binding PF10199.9 EMC97910.1 - 3.6e-11 43.7 2.4 4.8e-11 43.3 1.6 1.6 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 SMBP PF16785.5 EMC97911.1 - 0.071 13.3 1.2 0.12 12.6 1.2 1.4 1 0 0 1 1 1 0 Small metal-binding protein DUF1275 PF06912.11 EMC97912.1 - 1.2e-43 149.3 7.2 1.6e-43 148.9 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DctQ PF04290.12 EMC97912.1 - 0.0078 16.1 1.9 0.0078 16.1 1.9 1.7 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2157 PF09925.9 EMC97912.1 - 0.31 10.8 4.8 0.25 11.1 0.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.6 EMC97912.1 - 1.4 8.6 6.3 0.53 9.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.15 EMC97912.1 - 2.6 8.5 9.8 0.52 10.8 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Ribosomal_L27A PF00828.19 EMC97913.1 - 1.6e-31 109.6 0.2 2.4e-31 109.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Bacteriocin_IIi PF11758.8 EMC97913.1 - 0.16 11.8 0.1 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin Glyco_transf_90 PF05686.12 EMC97914.1 - 8.6e-13 48.0 4.8 6.6e-05 22.0 0.3 4.0 3 1 0 3 3 3 3 Glycosyl transferase family 90 DUF4817 PF16087.5 EMC97914.1 - 0.017 14.9 1.1 0.042 13.7 1.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Cyclin PF08613.11 EMC97918.1 - 4.1e-12 46.8 0.0 6.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EMC97918.1 - 0.053 13.3 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain SOG2 PF10428.9 EMC97919.1 - 3.7 6.6 38.2 5.9 6.0 38.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CTU2 PF10288.9 EMC97920.1 - 2e-13 50.6 1.5 6.7e-12 45.7 0.0 2.8 2 1 1 3 3 3 2 Cytoplasmic tRNA 2-thiolation protein 2 DZR PF12773.7 EMC97920.1 - 6.3 6.9 7.0 14 5.8 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon Bystin PF05291.11 EMC97922.1 - 1.3e-133 444.8 0.0 1.6e-133 444.5 0.0 1.1 1 0 0 1 1 1 1 Bystin DIOX_N PF14226.6 EMC97924.1 - 2.1e-24 86.5 0.0 3.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMC97924.1 - 4.1e-19 69.0 0.0 6.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.14 EMC97925.1 - 2.1e-24 86.8 0.1 2.7e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase LDB19 PF13002.7 EMC97927.1 - 8.3e-41 139.8 0.1 2e-40 138.6 0.1 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 EMC97927.1 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 EMC97927.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein Amidohydro_1 PF01979.20 EMC97929.1 - 5.8e-41 140.9 0.1 6.9e-41 140.7 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMC97929.1 - 9e-16 58.4 2.3 1.8e-11 44.2 0.2 2.5 1 1 1 2 2 2 2 Amidohydrolase family DeoC PF01791.9 EMC97929.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase COMPASS-Shg1 PF05205.12 EMC97930.1 - 3.8e-22 78.9 0.0 3.8e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 UPF0052 PF01933.18 EMC97932.1 - 1.5e-64 218.0 0.0 2.1e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 GFO_IDH_MocA PF01408.22 EMC97933.1 - 4.2e-23 82.5 0.1 7.3e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMC97933.1 - 8.2e-12 45.2 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EMC97933.1 - 0.0094 16.6 0.1 0.018 15.7 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain MFS_1 PF07690.16 EMC97934.1 - 6.3e-05 22.1 27.2 0.00029 19.9 23.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-MYND PF01753.18 EMC97935.1 - 1.8e-10 40.7 14.1 4.3e-10 39.5 14.1 1.7 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 EMC97935.1 - 0.86 7.4 5.3 0.99 7.2 5.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Nha1_C PF08619.10 EMC97937.1 - 2.6e-114 383.0 54.7 3.4e-114 382.6 54.7 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EMC97937.1 - 2.2e-82 276.9 20.6 2.7e-82 276.6 20.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4190 PF13828.6 EMC97937.1 - 0.006 16.3 5.0 0.11 12.3 0.1 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4190) YrhC PF14143.6 EMC97937.1 - 3.4 7.8 4.2 1.6 8.9 0.7 2.2 2 0 0 2 2 2 0 YrhC-like protein Mpv17_PMP22 PF04117.12 EMC97939.1 - 2.9e-12 46.6 1.2 1.8e-11 44.1 0.8 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family NADH_oxidored PF08040.11 EMC97939.1 - 0.053 13.2 0.1 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 MNLL subunit SprT-like PF10263.9 EMC97940.1 - 0.00027 20.8 0.0 0.00073 19.4 0.0 1.7 1 0 0 1 1 1 1 SprT-like family Cupin_8 PF13621.6 EMC97941.1 - 8.3e-68 228.8 0.1 9.6e-68 228.6 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EMC97941.1 - 3.9e-06 26.6 0.1 0.0085 15.6 0.0 2.9 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.22 EMC97941.1 - 0.0086 16.5 0.0 0.37 11.2 0.0 2.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase EF-hand_4 PF12763.7 EMC97942.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EMC97942.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 EF hand DNA_ligase_A_M PF01068.21 EMC97943.1 - 1.5e-43 148.8 0.0 3.1e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EMC97943.1 - 2.1e-43 148.7 0.0 4.4e-43 147.6 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 EMC97943.1 - 3.7e-22 78.5 0.0 3.4e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 EMC97943.1 - 7e-17 62.2 0.0 1.4e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 EMC97943.1 - 1.3e-15 57.8 0.3 4.4e-15 56.1 0.0 2.1 2 0 0 2 2 1 1 ATP dependent DNA ligase C terminal region LIG3_BRCT PF16759.5 EMC97943.1 - 2.7e-06 27.6 0.0 0.0086 16.3 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT PF00533.26 EMC97943.1 - 8.2e-06 26.1 0.0 0.00011 22.5 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 EMC97943.1 - 1.2e-05 25.4 0.1 3.6e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.7 EMC97943.1 - 0.007 16.3 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 2 twin BRCT domain MEA1 PF06910.11 EMC97943.1 - 0.012 16.3 0.1 0.033 14.8 0.1 1.7 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) mRNA_cap_enzyme PF01331.19 EMC97943.1 - 0.15 11.8 0.4 0.68 9.7 0.0 2.3 3 0 0 3 3 3 0 mRNA capping enzyme, catalytic domain TMEM232 PF15877.5 EMC97943.1 - 0.17 10.9 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 232 DUF4604 PF15377.6 EMC97945.1 - 2e-22 80.5 14.4 2.3e-22 80.2 14.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) SRP-alpha_N PF04086.13 EMC97945.1 - 0.17 11.8 8.9 0.2 11.6 8.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Glyco_transf_15 PF01793.16 EMC97946.1 - 6.1e-98 328.1 9.7 3e-65 220.6 2.6 2.1 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase 4HBT_3 PF13622.6 EMC97947.1 - 1.3e-31 110.8 0.0 1.6e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EMC97947.1 - 1.1e-05 25.2 2.4 0.0012 18.6 1.0 3.4 2 2 1 3 3 3 1 Acyl-CoA thioesterase Sugar_tr PF00083.24 EMC97949.1 - 1.1e-127 426.7 38.4 1.2e-127 426.5 38.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC97949.1 - 8.9e-27 93.9 61.6 1.2e-24 86.9 34.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMC97949.1 - 0.0004 19.0 12.6 0.0051 15.3 4.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) TPR_14 PF13428.6 EMC97949.1 - 0.091 13.6 0.6 0.19 12.6 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_N PF08240.12 EMC97950.1 - 7.5e-25 86.9 3.6 1.3e-24 86.1 3.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC97950.1 - 1.8e-14 53.9 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC97950.1 - 0.033 15.3 0.0 0.061 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3306 PF11748.8 EMC97950.1 - 0.06 14.2 0.3 0.1 13.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) WYL_3 PF18488.1 EMC97950.1 - 0.11 12.9 0.2 0.23 11.8 0.2 1.4 1 0 0 1 1 1 0 WYL domain 2-Hacid_dh_C PF02826.19 EMC97950.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NUDE_C PF04880.13 EMC97950.1 - 3.7 8.0 6.2 5.7 7.4 6.2 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Pyr_redox_2 PF07992.14 EMC97951.1 - 1.6e-51 175.3 0.0 2e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC97951.1 - 1.6e-10 41.4 0.0 5.1e-09 36.6 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC97951.1 - 0.0011 18.3 0.1 1.1 8.5 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pmp3 PF01679.17 EMC97952.1 - 3.6e-16 59.1 12.8 4.4e-16 58.8 12.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator FAM76 PF16046.5 EMC97952.1 - 0.079 12.3 0.9 0.097 12.0 0.9 1.1 1 0 0 1 1 1 0 FAM76 protein CLN3 PF02487.17 EMC97952.1 - 0.093 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 CLN3 protein Ctr PF04145.15 EMC97952.1 - 0.19 12.3 0.0 0.24 12.0 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family HemY_N PF07219.13 EMC97952.1 - 0.4 10.9 2.4 0.62 10.3 0.4 2.1 1 1 1 2 2 2 0 HemY protein N-terminus Rrn6 PF10214.9 EMC97952.1 - 5.6 5.3 9.6 6.8 5.1 9.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Glyco_hydro_28 PF00295.17 EMC97953.1 - 3.7e-40 138.0 13.4 4.2e-39 134.5 8.5 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 LRRC37 PF15779.5 EMC97953.1 - 0.2 12.0 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat-containing protein 37 family DUF4598 PF15370.6 EMC97954.1 - 9.3e-25 87.3 5.3 9.3e-25 87.3 5.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) FOG_N PF15888.5 EMC97954.1 - 0.0096 16.3 1.0 0.018 15.4 0.9 1.5 1 1 0 1 1 1 1 Folded gastrulation N-terminus Treacle PF03546.14 EMC97954.1 - 0.052 12.4 4.8 0.13 11.1 0.3 2.0 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle CLZ PF16526.5 EMC97954.1 - 3.3 8.1 6.5 2.8 8.4 0.1 2.9 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IF4E PF01652.18 EMC97955.1 - 2.3e-38 131.5 0.3 2.8e-38 131.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Plavaka PF18759.1 EMC97955.1 - 0.012 14.8 0.2 0.032 13.5 0.4 1.5 2 0 0 2 2 2 0 Plavaka transposase Porphobil_deam PF01379.20 EMC97956.1 - 2.3e-74 249.3 0.2 6.3e-74 247.9 0.0 1.7 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EMC97956.1 - 4.6e-18 65.4 0.0 8.4e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Med17 PF10156.9 EMC97956.1 - 0.076 11.7 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF2263 PF10021.9 EMC97958.1 - 6e-17 62.4 0.0 2.9e-16 60.2 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Dimeth_Pyl PF09505.10 EMC97958.1 - 0.17 10.4 0.1 0.25 9.8 0.1 1.1 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) TRAPP PF04051.16 EMC97959.1 - 4.2e-39 133.6 0.0 5e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Las1 PF04031.13 EMC97960.1 - 1.9e-46 157.9 1.6 1.9e-46 157.9 1.6 1.6 2 0 0 2 2 2 1 Las1-like NAD_kinase PF01513.21 EMC97961.1 - 4.7e-72 242.7 0.0 6.6e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Arylsulfotran_2 PF14269.6 EMC97962.1 - 1.4e-80 270.9 0.1 1.6e-80 270.6 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMC97962.1 - 3.7e-12 45.9 0.0 8.5e-11 41.4 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DSPc PF00782.20 EMC97963.1 - 5.5e-29 100.7 0.0 6.1e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EMC97963.1 - 0.0029 17.8 0.0 0.0038 17.4 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 EMC97963.1 - 0.0092 16.3 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EMC97963.1 - 0.056 13.0 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EMC97963.1 - 0.093 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family WD40 PF00400.32 EMC97964.1 - 1.6e-28 98.3 3.5 2.2e-05 25.1 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC97964.1 - 1.1e-05 25.7 0.1 0.68 10.3 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EMC97964.1 - 5.4e-05 22.7 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EMC97964.1 - 0.00014 20.7 0.0 0.034 12.9 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like Ge1_WD40 PF16529.5 EMC97964.1 - 0.003 16.6 0.1 0.027 13.4 0.0 2.5 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 EMC97964.1 - 0.0038 16.5 0.0 1.8 7.8 0.1 3.2 3 1 0 3 3 3 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 EMC97964.1 - 0.042 13.8 0.1 3.3 7.8 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Helveticin_J PF17312.2 EMC97964.1 - 0.063 12.4 0.1 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Bacteriocin helveticin-J PH_BEACH PF14844.6 EMC97964.1 - 0.16 12.1 0.1 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH zf-C2H2 PF00096.26 EMC97965.1 - 2.6e-08 33.8 22.7 0.32 11.5 0.2 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC97965.1 - 4.6e-08 33.3 22.1 0.59 11.1 0.9 6.8 7 0 0 7 7 7 3 C2H2-type zinc finger FOXP-CC PF16159.5 EMC97965.1 - 0.0031 18.1 10.9 0.27 11.9 0.0 4.4 3 1 1 4 4 4 1 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 EMC97965.1 - 0.007 16.2 3.7 1.9 8.4 0.0 3.8 3 0 0 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 EMC97965.1 - 0.032 14.5 16.4 0.058 13.7 3.5 3.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EMC97965.1 - 0.69 10.3 0.0 0.69 10.3 0.0 4.6 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC97965.1 - 0.91 10.0 14.4 15 6.2 0.1 4.9 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EMC97965.1 - 1.3 9.2 10.8 8 6.6 2.1 3.5 3 1 0 3 3 3 0 Aberrant zinc-finger IBR PF01485.21 EMC97965.1 - 1.3 9.3 17.6 22 5.3 0.2 4.2 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain DUF983 PF06170.12 EMC97965.1 - 1.5 9.3 5.0 6.9 7.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF983) GAGA PF09237.11 EMC97965.1 - 2.4 8.0 5.3 2.1 8.2 0.1 2.6 2 1 0 2 2 2 0 GAGA factor Zn-ribbon_8 PF09723.10 EMC97965.1 - 2.4 8.3 14.0 3.3 7.9 1.2 3.8 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 EMC97965.1 - 2.6 8.4 20.0 0.24 11.8 0.4 4.1 3 2 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 EMC97965.1 - 5.1 7.9 13.2 10 7.0 2.0 3.4 3 0 0 3 3 3 0 zinc-ribbon family Cyanate_lyase PF02560.14 EMC97967.1 - 1.6e-32 111.2 0.0 2.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 EMC97967.1 - 0.0073 16.3 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix VPS38 PF17649.1 EMC97968.1 - 7.5e-10 38.2 0.0 7e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting 38 Atg14 PF10186.9 EMC97968.1 - 8.2e-10 38.3 16.1 8.2e-10 38.3 16.1 2.3 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 EMC97968.1 - 0.036 12.6 0.6 0.039 12.5 0.6 1.2 1 0 0 1 1 1 0 Macoilin family LytR_C PF13399.6 EMC97968.1 - 0.1 13.6 0.3 0.23 12.4 0.3 1.6 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Borrelia_P83 PF05262.11 EMC97968.1 - 5.2 5.4 10.8 7.7 4.9 10.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 EMC97968.1 - 7 5.9 9.9 13 5.0 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mhr1 PF12829.7 EMC97969.1 - 1.9e-30 104.8 0.0 3.5e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Gram_pos_anchor PF00746.21 EMC97969.1 - 8.1 6.5 7.5 0.41 10.6 1.7 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Rep_fac-A_3 PF08661.11 EMC97970.1 - 1.5e-27 96.0 0.1 1.6e-27 95.9 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF1308 PF07000.11 EMC97971.1 - 1.4e-12 47.9 0.0 1.1e-11 44.9 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 EMC97971.1 - 0.017 14.4 0.1 5.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5614) SRP9-21 PF05486.12 EMC97972.1 - 3.7e-33 113.8 0.2 6.8e-33 112.9 0.2 1.4 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Fungal_trans PF04082.18 EMC97973.1 - 7e-21 74.4 0.4 2.9e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EMC97973.1 - 1.2e-09 38.0 12.4 0.0002 21.7 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC97973.1 - 2.7e-07 30.7 12.6 2.3e-06 27.8 7.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC97973.1 - 0.00041 20.9 14.4 0.038 14.8 2.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EMC97973.1 - 3.4 7.5 8.2 14 5.5 0.9 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type GATase_4 PF13230.6 EMC97974.1 - 8.9e-13 47.8 0.1 3e-10 39.5 0.1 3.1 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 EMC97974.1 - 1e-07 32.2 0.0 1e-06 29.0 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain Cellulase PF00150.18 EMC97975.1 - 2.3e-36 125.7 0.9 3.1e-36 125.2 0.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RyR PF02026.16 EMC97976.1 - 3.9e-07 30.2 0.1 0.00028 21.0 0.0 2.4 2 0 0 2 2 2 2 RyR domain AAA PF00004.29 EMC97976.1 - 0.024 15.0 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EMC97976.1 - 0.028 15.0 0.0 0.071 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMC97976.1 - 0.035 14.5 0.3 1.1 9.7 0.1 2.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 EMC97976.1 - 0.18 11.8 0.0 0.57 10.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 EMC97976.1 - 0.2 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain CorA PF01544.18 EMC97977.1 - 0.0092 15.3 3.6 0.0092 15.3 3.6 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein KxDL PF10241.9 EMC97977.1 - 0.041 14.1 0.1 0.041 14.1 0.1 2.2 3 1 0 3 3 3 0 Uncharacterized conserved protein AMP-binding PF00501.28 EMC97978.1 - 6.4e-84 282.0 0.0 8.2e-84 281.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC97978.1 - 1.1e-15 58.3 0.3 2.5e-15 57.2 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EMC97978.1 - 0.0045 15.9 0.0 0.084 11.7 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 EMC97978.1 - 0.094 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 RTX C-terminal domain MFS_1 PF07690.16 EMC97979.1 - 1.5e-35 122.7 31.2 1.5e-35 122.7 31.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PEP_mutase PF13714.6 EMC97980.1 - 3.9e-42 144.4 0.9 4.5e-42 144.2 0.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EMC97980.1 - 3.9e-18 65.2 0.7 5e-18 64.9 0.7 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DnaJ PF00226.31 EMC97981.1 - 2.3e-14 53.2 0.5 5.4e-14 52.1 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain HET PF06985.11 EMC97981.1 - 1.4e-13 51.5 2.5 1.7e-13 51.2 0.1 2.5 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) DUF1772 PF08592.11 EMC97982.1 - 1.3e-19 70.9 1.0 1.6e-19 70.6 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) AMP-binding PF00501.28 EMC97983.1 - 1.5e-35 122.7 0.0 2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EMC97983.1 - 5e-10 39.1 0.6 5e-10 39.1 0.6 2.4 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EMC97983.1 - 0.0002 22.3 0.0 0.00057 20.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TIM PF00121.18 EMC97984.1 - 6.6e-88 294.2 0.1 7.4e-88 294.0 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase SnoaL_2 PF12680.7 EMC97985.1 - 0.017 15.8 0.1 0.023 15.3 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain Aminotran_1_2 PF00155.21 EMC97986.1 - 3.1e-57 194.4 0.0 4.2e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Arylsulfotran_2 PF14269.6 EMC97987.1 - 2.1e-42 145.6 0.0 2.9e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMC97987.1 - 6.9e-09 35.1 0.4 1.5e-07 30.6 0.4 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) HAD_2 PF13419.6 EMC97988.1 - 3.8e-22 79.2 0.0 6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMC97988.1 - 2e-10 41.3 0.0 7.4e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC97988.1 - 0.00031 20.7 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EMC97988.1 - 0.00073 20.0 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EMC97988.1 - 0.065 12.8 0.7 4.7 6.8 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase DUF1989 PF09347.10 EMC97989.1 - 5e-41 140.1 0.0 7.8e-31 107.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1989) CDC45 PF02724.14 EMC97989.1 - 0.15 10.3 9.9 0.25 9.6 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein GET2 PF08690.10 EMC97989.1 - 6.2 6.4 11.5 12 5.4 11.5 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Zip PF02535.22 EMC97989.1 - 6.4 5.9 5.4 11 5.2 5.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Lipase_GDSL_2 PF13472.6 EMC97990.1 - 2.3e-06 28.1 0.0 0.00028 21.4 0.0 2.3 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMC97990.1 - 0.059 13.3 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Glyco_hydr_116N PF12215.8 EMC97990.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Lipocalin_5 PF13924.6 EMC97991.1 - 9.8e-31 106.4 0.0 1.1e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain K-cyclin_vir_C PF09080.10 EMC97992.1 - 0.038 14.4 0.1 0.038 14.4 0.1 1.1 1 0 0 1 1 1 0 K cyclin, C terminal MFS_1 PF07690.16 EMC97993.1 - 9.9e-31 106.9 34.9 3.8e-17 62.2 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC97993.1 - 0.00054 18.9 21.9 0.0027 16.7 21.8 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EMC97993.1 - 0.0015 16.9 5.2 0.19 10.0 0.1 2.8 2 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EMC97993.1 - 0.016 14.1 20.0 2.5 6.9 19.0 2.1 1 1 0 1 1 1 0 MFS_1 like family UNC-93 PF05978.16 EMC97993.1 - 0.68 9.6 10.7 2.7 7.7 1.7 3.0 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 CRPA PF05745.11 EMC97993.1 - 5.9 6.9 5.5 9.6 6.2 0.0 3.0 2 1 1 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Piwi PF02171.17 EMC97994.1 - 1.2e-76 257.9 0.0 1.5e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EMC97994.1 - 1.3e-13 50.4 0.0 4.7e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 EMC97994.1 - 7.9e-13 49.2 0.0 2e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 EMC97994.1 - 9.3e-08 32.0 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 EMC97994.1 - 6.5e-06 26.4 0.0 1.9e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain Complex1_LYR_2 PF13233.6 EMC97996.1 - 4.6e-21 75.4 0.1 5.8e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EMC97996.1 - 0.012 15.6 0.3 0.021 14.9 0.2 1.7 1 1 0 1 1 1 0 Complex 1 protein (LYR family) MMR_HSR1 PF01926.23 EMC97997.1 - 7.4e-20 71.1 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMC97997.1 - 1.9e-06 27.9 0.1 0.00011 22.2 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EMC97997.1 - 8.1e-05 22.7 0.0 0.0096 16.0 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 EMC97997.1 - 0.0002 21.0 0.0 0.0044 16.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EMC97997.1 - 0.00039 20.0 0.0 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.13 EMC97997.1 - 0.008 15.3 0.0 0.79 8.7 0.0 2.0 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EMC97997.1 - 0.027 15.0 0.0 0.045 14.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EMC97997.1 - 0.12 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EMC97997.1 - 0.13 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EMC97997.1 - 0.25 10.6 0.0 0.97 8.6 0.0 1.8 2 0 0 2 2 2 0 Septin Glyco_hydro_2_N PF02837.18 EMC97998.1 - 6.3e-12 45.7 0.0 1.6e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EMC97998.1 - 2.3e-10 40.1 0.0 6e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EMC97998.1 - 3.8e-10 40.4 0.5 1.2e-09 38.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Aldo_ket_red PF00248.21 EMC97999.1 - 3.7e-55 187.2 0.0 4.2e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SET PF00856.28 EMC98000.1 - 0.0002 21.8 0.0 0.00043 20.7 0.0 1.7 1 1 0 1 1 1 1 SET domain DUF2076 PF09849.9 EMC98001.1 - 5.8e-12 46.2 9.9 6.7e-12 46.0 9.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EMC98001.1 - 0.0026 17.8 1.8 0.0039 17.3 1.8 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EMC98001.1 - 0.0033 17.4 0.8 0.005 16.8 0.8 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Bindin PF02084.15 EMC98001.1 - 1.8 8.8 6.5 4.3 7.6 6.1 1.8 1 1 1 2 2 2 0 Bindin DUF3275 PF11679.8 EMC98001.1 - 2 8.3 4.1 3.3 7.6 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) TFIIA PF03153.13 EMC98001.1 - 2.4 8.0 5.5 2.9 7.8 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Septin PF00735.18 EMC98002.1 - 2.8e-32 112.1 0.0 7.6e-19 68.1 0.0 2.6 2 1 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 EMC98002.1 - 0.00014 21.9 0.0 0.00028 20.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EMC98002.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Roc PF08477.13 EMC98002.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Spem1 PF15670.5 EMC98002.1 - 0.014 15.0 0.2 0.047 13.3 0.0 2.0 2 0 0 2 2 2 0 Spermatid maturation protein 1 Nop14 PF04147.12 EMC98002.1 - 0.028 12.6 9.0 0.04 12.2 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family Ras PF00071.22 EMC98002.1 - 0.18 11.4 0.1 0.65 9.6 0.1 1.9 1 1 0 1 1 1 0 Ras family TFIIF_alpha PF05793.12 EMC98002.1 - 0.55 8.8 9.6 0.92 8.0 9.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 EMC98002.1 - 0.58 9.4 16.5 0.94 8.7 16.5 1.2 1 0 0 1 1 1 0 BUD22 Cnd2 PF05786.14 EMC98002.1 - 1 7.9 12.4 1.5 7.4 12.4 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 SDA1 PF05285.12 EMC98002.1 - 3.2 7.1 10.5 4.6 6.6 10.5 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EMC98002.1 - 3.8 5.9 10.3 5.3 5.5 10.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3720 PF12517.8 EMC98002.1 - 7.9 7.5 15.2 14 6.7 0.2 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3720) RRM_1 PF00076.22 EMC98003.1 - 0.0021 17.8 0.0 0.0071 16.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLH PF01738.18 EMC98005.1 - 2.4e-25 89.4 0.0 3e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 EMC98005.1 - 0.031 13.8 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase zf-C3HC4 PF00097.25 EMC98007.1 - 0.096 12.6 1.7 0.3 11.0 1.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC98007.1 - 0.37 11.2 2.8 0.86 10.0 2.8 1.7 1 0 0 1 1 1 0 Ring finger domain ADH_N PF08240.12 EMC98009.1 - 2.2e-29 101.5 0.2 4.3e-29 100.6 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC98009.1 - 6.7e-21 74.6 0.1 1.2e-20 73.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC98009.1 - 0.00076 20.5 0.0 0.0013 19.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EMC98009.1 - 0.027 14.0 0.1 0.053 13.0 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 EMC98009.1 - 0.08 12.3 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polyketide_cyc2 PF10604.9 EMC98010.1 - 3e-05 24.3 0.0 3.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport p450 PF00067.22 EMC98011.1 - 4.4e-60 203.7 0.0 5.5e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AHD PF17793.1 EMC98011.1 - 0.01 15.6 1.6 5.1 7.0 0.1 3.4 3 0 0 3 3 3 0 ANC1 homology domain (AHD) ECH_1 PF00378.20 EMC98012.1 - 5.6e-26 91.4 0.0 7.5e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMC98012.1 - 2.5e-08 33.8 0.0 3.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FSH1 PF03959.13 EMC98013.1 - 7.8e-57 192.4 0.0 1.1e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EMC98013.1 - 0.00016 22.4 0.9 0.00028 21.6 0.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EMC98013.1 - 0.0019 17.7 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EMC98013.1 - 0.066 13.0 0.8 7.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 EMC98013.1 - 0.071 12.6 0.0 0.48 9.9 0.0 2.1 2 1 0 2 2 2 0 Esterase PHB depolymerase WD40 PF00400.32 EMC98014.1 - 4.5e-21 74.8 22.7 0.00036 21.3 0.4 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EMC98014.1 - 6.5e-06 24.9 0.4 0.0072 14.9 0.0 3.9 4 0 0 4 4 4 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 EMC98014.1 - 0.0019 18.6 0.6 1.5 9.4 0.0 3.6 4 0 0 4 4 4 1 PQQ-like domain PD40 PF07676.12 EMC98014.1 - 0.012 15.6 0.4 0.053 13.5 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyoxal_oxid_N PF07250.11 EMC98014.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus SecE PF00584.20 EMC98015.1 - 3e-15 55.9 0.0 3.4e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Sec20 PF03908.13 EMC98015.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Sec20 DUF357 PF04010.13 EMC98015.1 - 0.2 11.7 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Cornifin PF02389.15 EMC98016.1 - 0.01 16.0 0.1 0.013 15.7 0.1 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family GPI2 PF06432.11 EMC98017.1 - 1.9e-131 437.7 1.5 2.2e-131 437.4 1.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Intg_mem_TP0381 PF09529.10 EMC98017.1 - 0.038 13.5 3.7 0.3 10.6 0.0 2.4 2 1 1 3 3 3 0 Integral membrane protein (intg_mem_TP0381) ADH_N PF08240.12 EMC98018.1 - 8.6e-16 57.8 0.5 1.5e-15 57.0 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC98018.1 - 1e-09 38.4 0.0 2.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EMC98018.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMC98018.1 - 0.0041 16.4 0.1 0.0067 15.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BTRD1 PF17660.1 EMC98018.1 - 0.083 12.7 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 Mor PF08765.11 EMC98019.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Mor transcription activator family DUF3357 PF11837.8 EMC98020.1 - 0.0071 16.8 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF997 PF06196.12 EMC98020.1 - 0.21 11.6 0.4 0.36 10.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) AcMNPV_Ac109 PF05054.12 EMC98020.1 - 0.24 10.4 0.4 0.42 9.6 0.4 1.3 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Phage_TAC_11 PF11836.8 EMC98020.1 - 0.25 11.5 0.5 2 8.6 0.1 2.3 1 1 1 2 2 2 0 Phage tail tube protein, GTA-gp10 EGF_2 PF07974.13 EMC98020.1 - 0.93 9.9 9.2 2.2 8.7 9.2 1.6 1 0 0 1 1 1 0 EGF-like domain Ribosomal_S27e PF01667.17 EMC98021.1 - 7.1e-29 99.3 6.8 8.7e-29 99.0 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 EMC98021.1 - 0.34 10.9 5.8 2.2 8.3 4.1 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-CSL PF05207.13 EMC98021.1 - 0.45 10.3 3.3 1.3 8.8 3.3 1.7 1 1 0 1 1 1 0 CSL zinc finger DeoC PF01791.9 EMC98022.1 - 5e-15 55.8 1.7 7.5e-15 55.2 1.7 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 EMC98022.1 - 0.0018 17.6 0.1 0.0025 17.1 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EMC98022.1 - 0.043 13.3 0.1 0.092 12.2 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.18 EMC98022.1 - 0.06 12.4 0.3 0.11 11.5 0.3 1.5 1 1 0 1 1 1 0 FMN-dependent dehydrogenase THDPS_N_2 PF14805.6 EMC98022.1 - 0.2 11.9 1.6 3.3 8.0 0.0 3.0 4 0 0 4 4 4 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal adh_short_C2 PF13561.6 EMC98023.1 - 1.9e-60 204.4 0.0 2.1e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC98023.1 - 5.4e-48 163.0 0.0 6.7e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC98023.1 - 4.2e-06 26.8 0.0 6.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMC98023.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EMC98023.1 - 0.06 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1652 PF07865.11 EMC98023.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Peptidase_C65 PF10275.9 EMC98024.1 - 1.3e-61 208.2 0.0 1.7e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain DUF3729 PF12526.8 EMC98024.1 - 3.4 9.3 6.8 6.6 8.3 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) PCI PF01399.27 EMC98026.1 - 6.1e-19 68.5 0.2 1.6e-18 67.1 0.2 1.8 1 0 0 1 1 1 1 PCI domain LZ3wCH PF18517.1 EMC98026.1 - 0.022 14.9 0.1 1.8 8.7 0.0 3.1 2 1 1 3 3 3 0 Leucine zipper with capping helix domain TPR_7 PF13176.6 EMC98026.1 - 0.11 12.6 0.7 48 4.3 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMC98026.1 - 3.6 7.9 8.1 3.2 8.1 0.3 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat CWC25 PF12542.8 EMC98027.1 - 1.6e-22 80.3 0.0 1.6e-22 80.3 0.0 4.0 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 EMC98027.1 - 9.6e-14 51.3 5.4 9.6e-14 51.3 5.4 4.8 4 1 1 5 5 5 2 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.22 EMC98028.1 - 4.3e-54 182.5 0.0 5e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC98028.1 - 1.3e-21 77.0 0.0 2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC98028.1 - 3e-09 36.6 0.0 4.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMC98028.1 - 0.00056 19.3 0.0 0.00073 19.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EMC98028.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EMC98028.1 - 0.0095 15.1 0.0 0.035 13.3 0.0 1.5 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EMC98028.1 - 0.033 14.3 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EMC98028.1 - 0.095 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Annexin PF00191.20 EMC98029.1 - 6.8e-23 80.5 1.4 8.8e-05 22.5 0.0 4.4 4 0 0 4 4 4 4 Annexin Ist1 PF03398.14 EMC98029.1 - 0.023 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Endosulfine PF04667.17 EMC98029.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region Methyltransf_25 PF13649.6 EMC98031.1 - 8.9e-13 48.8 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC98031.1 - 4.9e-09 36.8 0.0 6.7e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC98031.1 - 6.7e-08 32.5 0.0 8.5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC98031.1 - 1.1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EMC98031.1 - 1.1e-07 31.9 0.0 1.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC98031.1 - 1.2e-07 32.3 0.0 1.7e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMC98031.1 - 0.0072 15.8 0.0 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 EMC98031.1 - 0.011 15.1 0.0 0.027 13.8 0.0 1.6 1 1 1 2 2 2 0 O-methyltransferase domain Ubie_methyltran PF01209.18 EMC98031.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DNA_pol_B PF00136.21 EMC98032.1 - 4.9e-104 348.6 0.0 7.5e-104 348.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EMC98032.1 - 9.7e-21 74.3 0.0 1.5e-11 44.1 0.0 3.3 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EMC98032.1 - 3e-17 62.9 6.2 3e-17 62.9 6.2 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EMC98032.1 - 0.049 12.5 0.3 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral dsDNA_bind PF01984.20 EMC98033.1 - 1.1e-35 122.2 14.3 1.4e-35 121.9 14.3 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain SDA1 PF05285.12 EMC98033.1 - 0.016 14.6 1.2 0.016 14.6 1.2 1.8 1 1 0 2 2 2 0 SDA1 Sec16_N PF12935.7 EMC98033.1 - 0.045 13.9 3.9 0.055 13.6 3.9 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus CD99L2 PF12301.8 EMC98033.1 - 0.32 11.3 4.9 2.6 8.3 1.5 2.1 2 0 0 2 2 2 0 CD99 antigen like protein 2 PAPS_reduct PF01507.19 EMC98035.1 - 9.4e-44 149.5 0.0 1.2e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.17 EMC98036.1 - 2.4e-87 291.9 0.0 3.5e-87 291.3 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EMC98036.1 - 6.7e-57 191.8 0.0 1e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EMC98036.1 - 5.5e-53 178.9 0.0 9.9e-53 178.1 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain SET PF00856.28 EMC98037.1 - 2.7e-11 44.2 0.0 3.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 SET domain Sas10_Utp3 PF04000.15 EMC98038.1 - 1.2e-15 57.9 0.4 1.2e-15 57.9 0.4 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family HSBP1 PF06825.12 EMC98038.1 - 0.099 12.5 0.2 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 HR1 PF02185.16 EMC98038.1 - 0.67 10.1 9.3 6.4 7.0 1.5 3.4 3 0 0 3 3 3 0 Hr1 repeat Coilin_N PF15862.5 EMC98038.1 - 1.6 8.5 10.1 0.49 10.2 2.6 2.4 2 0 0 2 2 2 0 Coilin N-terminus Ras PF00071.22 EMC98039.1 - 9.2e-55 184.7 0.0 1.1e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC98039.1 - 1.1e-20 74.1 0.0 1.9e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC98039.1 - 2.4e-07 30.3 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMC98039.1 - 0.00089 18.8 0.0 0.0022 17.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TfoX_N PF04993.13 EMC98039.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 TfoX N-terminal domain PH_TFIIH PF08567.11 EMC98040.1 - 6.4e-25 87.3 0.0 1.4e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 EMC98040.1 - 4e-21 74.8 5.3 5.7e-11 42.2 0.7 3.4 3 0 0 3 3 3 2 BSD domain DUF3665 PF12427.8 EMC98040.1 - 0.15 11.8 0.9 0.4 10.4 0.9 1.6 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase GDPD PF03009.17 EMC98041.1 - 8.5e-55 186.3 0.0 1.2e-54 185.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.6 EMC98041.1 - 0.012 16.1 0.0 0.033 14.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMC98042.1 - 3.4e-06 27.6 0.0 0.12 13.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC98042.1 - 3.6e-05 24.2 0.1 1.3 9.7 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC98042.1 - 0.00034 20.8 0.0 0.54 11.0 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Helo_like_N PF17111.5 EMC98042.1 - 0.0016 17.9 0.2 0.0038 16.6 0.2 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank PF00023.30 EMC98042.1 - 0.0021 18.4 0.0 2.7 8.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EMC98042.1 - 0.019 15.3 0.0 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) ENTH PF01417.20 EMC98043.1 - 9.8e-46 154.9 0.0 1.5e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 EMC98043.1 - 0.0034 17.2 5.3 0.0072 16.2 0.6 2.7 2 0 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.16 EMC98043.1 - 0.0062 15.6 0.0 0.009 15.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.6 EMC98043.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) VHS PF00790.19 EMC98043.1 - 0.049 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 VHS domain Ribosomal_S7 PF00177.21 EMC98044.1 - 4.3e-28 97.8 0.0 7.5e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Coq4 PF05019.13 EMC98047.1 - 9.3e-95 316.1 0.0 1.2e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ApbA_C PF08546.11 EMC98048.1 - 1.7e-31 109.0 0.5 3.4e-31 108.0 0.5 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EMC98048.1 - 3.4e-25 88.5 0.1 6.8e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Ribosomal_S14 PF00253.21 EMC98050.1 - 7.7e-21 73.6 0.9 7.7e-21 73.6 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e GFO_IDH_MocA PF01408.22 EMC98052.1 - 3.8e-16 60.0 0.0 6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMC98052.1 - 6.2e-06 26.2 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PUL PF08324.11 EMC98053.1 - 6.3e-48 163.4 0.2 8.7e-48 162.9 0.2 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EMC98053.1 - 1.2e-37 129.1 0.0 1.9e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 EMC98053.1 - 1.2e-16 60.6 0.0 5e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EMC98053.1 - 1.5e-06 28.6 0.0 1e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EMC98053.1 - 3.1e-06 26.8 0.0 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 EMC98053.1 - 0.0029 17.5 0.1 0.0055 16.6 0.1 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF2847 PF11009.8 EMC98053.1 - 0.0033 17.3 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) T4_deiodinase PF00837.17 EMC98053.1 - 0.0099 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Iodothyronine deiodinase AhpC-TSA PF00578.21 EMC98053.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 EMC98053.1 - 0.031 14.6 0.0 0.096 13.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 EMC98053.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Redoxin DIM1 PF02966.16 EMC98053.1 - 0.078 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Glutaredoxin PF00462.24 EMC98053.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin GDA1_CD39 PF01150.17 EMC98054.1 - 5.7e-101 338.2 0.0 7e-101 337.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ribosomal_S11 PF00411.19 EMC98054.1 - 0.068 13.6 0.3 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S11 GCV_T PF01571.21 EMC98055.1 - 0.00032 20.2 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DCP2 PF05026.13 EMC98056.1 - 2.1e-28 98.4 0.3 5.5e-28 97.1 0.0 1.8 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 EMC98056.1 - 1.4e-16 60.7 0.1 2.4e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DnaJ PF00226.31 EMC98057.1 - 1.1e-18 67.1 0.2 2.2e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain UPF0242 PF06785.11 EMC98057.1 - 7.1 6.7 5.9 12 5.9 5.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pro-kuma_activ PF09286.11 EMC98058.1 - 1.3e-38 132.5 0.1 2.1e-38 131.8 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMC98058.1 - 0.00012 21.4 1.2 0.00023 20.5 1.2 1.3 1 0 0 1 1 1 1 Subtilase family DUF3429 PF11911.8 EMC98059.1 - 1.1e-42 145.8 9.1 1.5e-42 145.3 9.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) VPS13_mid_rpt PF16910.5 EMC98060.1 - 1.9e-98 328.6 16.6 1.1e-93 313.0 3.8 5.5 5 0 0 5 5 5 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 EMC98060.1 - 5e-96 321.2 0.0 2.4e-94 315.7 0.0 3.0 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 EMC98060.1 - 1.4e-83 280.3 2.2 4.1e-82 275.5 0.0 3.7 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EMC98060.1 - 1.9e-73 246.1 4.7 5e-68 228.4 0.3 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EMC98060.1 - 1.4e-39 134.8 0.4 7.4e-39 132.5 0.4 2.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EMC98060.1 - 8.2e-08 32.5 0.1 8.3e-07 29.3 0.1 2.8 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain DUF3040 PF11239.8 EMC98060.1 - 0.3 11.4 1.7 0.73 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF896 PF05979.12 EMC98060.1 - 3.9 7.4 15.4 1.6 8.7 0.9 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) Complex1_51K PF01512.17 EMC98063.1 - 2.6e-47 160.5 0.0 4.2e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EMC98063.1 - 1.6e-28 98.6 0.3 3.5e-28 97.5 0.3 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EMC98063.1 - 2.2e-08 33.9 0.0 4.3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Cyclase PF04199.13 EMC98064.1 - 4e-15 56.3 0.0 5.4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase ECH_1 PF00378.20 EMC98065.1 - 3.9e-21 75.5 0.0 4.8e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMC98065.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase RasGEF PF00617.19 EMC98066.1 - 4.3e-60 202.9 0.3 1.1e-59 201.7 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EMC98066.1 - 2.3e-26 92.1 0.0 4.4e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EMC98066.1 - 7.9e-14 51.0 0.1 1.8e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMC98066.1 - 9.7e-14 51.0 0.1 2.1e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMC98066.1 - 1.4e-11 43.9 0.0 3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EMC98066.1 - 0.0002 21.3 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 WW domain Fungal_trans PF04082.18 EMC98069.1 - 1.5e-16 60.3 3.2 2.3e-16 59.6 3.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EMC98069.1 - 3.9e-07 30.2 15.3 3e-05 24.2 6.3 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EMC98069.1 - 7.5e-05 23.0 14.9 0.0088 16.4 5.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC98069.1 - 0.00028 21.5 12.9 0.15 13.0 1.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EMC98069.1 - 0.038 14.7 0.3 1.2 9.8 0.0 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats PyrI_C PF02748.15 EMC98069.1 - 0.093 12.7 1.4 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ALG11_N PF15924.5 EMC98069.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 ALG11 mannosyltransferase N-terminus AMP-binding PF00501.28 EMC98070.1 - 6.2e-49 166.7 0.0 8e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 EMC98070.1 - 0.23 10.3 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter AA_permease_2 PF13520.6 EMC98071.1 - 9.3e-53 179.6 56.3 1.1e-52 179.3 56.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC98071.1 - 1.5e-14 53.5 48.3 1.9e-14 53.1 48.3 1.1 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.16 EMC98072.1 - 7e-51 173.6 1.3 8.5e-51 173.3 1.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family YcgL PF05166.13 EMC98072.1 - 0.18 12.2 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 YcgL domain Thioredoxin PF00085.20 EMC98075.1 - 4.2e-56 187.3 0.0 1.3e-27 95.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EMC98075.1 - 2.5e-21 76.3 0.4 2.1e-20 73.4 0.0 2.2 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EMC98075.1 - 1e-15 58.1 0.0 6.9e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EMC98075.1 - 3.3e-12 46.4 0.0 3e-05 23.5 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EMC98075.1 - 2.9e-08 33.7 0.1 0.0044 16.9 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 EMC98075.1 - 8.9e-08 32.2 0.0 0.0048 17.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EMC98075.1 - 1.1e-07 32.0 0.0 0.0024 18.2 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 EMC98075.1 - 5.3e-06 26.4 0.0 0.0073 16.2 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein ERp29_N PF07912.13 EMC98075.1 - 7.1e-06 26.2 0.0 0.00025 21.2 0.0 2.3 2 0 0 2 2 2 1 ERp29, N-terminal domain Redoxin PF08534.10 EMC98075.1 - 0.00041 20.1 0.2 0.75 9.5 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 EMC98075.1 - 0.00048 19.9 0.1 0.25 11.1 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EMC98075.1 - 0.00066 19.6 0.9 2.8 7.8 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like domain Glutaredoxin PF00462.24 EMC98075.1 - 0.0013 18.9 0.8 3.1 8.1 0.0 3.5 3 1 0 3 3 2 2 Glutaredoxin HyaE PF07449.11 EMC98075.1 - 0.0034 17.3 0.0 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 EMC98075.1 - 0.0082 16.2 0.0 2.3 8.3 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.6 EMC98075.1 - 0.012 15.8 1.2 16 5.6 0.1 3.7 2 2 2 4 4 4 0 Thioredoxin DDE_Tnp_1_2 PF13586.6 EMC98075.1 - 0.045 14.1 0.0 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain GAS PF13851.6 EMC98075.1 - 0.056 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding OHCU_decarbox PF09349.10 EMC98078.1 - 3.5e-49 167.2 0.6 4e-49 167.1 0.6 1.0 1 0 0 1 1 1 1 OHCU decarboxylase S6PP PF05116.13 EMC98078.1 - 0.0089 15.6 0.1 0.011 15.2 0.1 1.4 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase MAP65_ASE1 PF03999.12 EMC98081.1 - 7.6e-77 259.4 10.7 7.6e-77 259.4 10.7 2.2 1 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Spectrin PF00435.21 EMC98081.1 - 0.2 12.1 12.3 0.61 10.6 1.6 3.6 3 1 0 3 3 3 0 Spectrin repeat Prominin PF05478.11 EMC98081.1 - 3 5.7 9.9 2.3 6.1 0.5 2.8 2 1 1 3 3 3 0 Prominin DUF680 PF05079.12 EMC98081.1 - 6.8 7.5 7.7 19 6.0 1.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF680) DUF533 PF04391.12 EMC98082.1 - 0.039 13.5 0.3 0.066 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF533) ETF_alpha PF00766.19 EMC98082.1 - 0.12 12.5 0.3 0.25 11.4 0.3 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain PT-VENN PF04829.13 EMC98082.1 - 0.54 10.4 2.8 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Rick_17kDa_Anti PF05433.15 EMC98082.1 - 0.83 9.6 9.6 0.21 11.5 1.8 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain RRM_1 PF00076.22 EMC98083.1 - 3.9e-09 36.2 0.0 7.8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UreD PF01774.17 EMC98084.1 - 5e-71 239.0 0.0 6.2e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 EMC98085.1 - 5.2e-35 119.8 0.0 5.1e-34 116.6 0.0 2.8 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.6 EMC98085.1 - 1.1e-05 25.7 0.4 0.0039 17.6 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EMC98085.1 - 0.017 15.4 0.7 3.2 8.3 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.7 EMC98085.1 - 0.018 15.1 0.0 0.51 10.4 0.0 2.6 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF4404 PF14357.6 EMC98085.1 - 0.06 14.0 0.7 0.66 10.6 0.7 2.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Trp_oprn_chp PF09534.10 EMC98085.1 - 0.16 11.8 5.2 0.19 11.5 0.1 3.4 4 0 0 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PTCB-BRCT PF12738.7 EMC98086.1 - 1.8e-43 146.3 1.5 7e-20 70.7 0.1 4.3 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 EMC98086.1 - 1.1e-30 105.9 0.0 6.1e-12 45.8 0.0 4.4 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EMC98086.1 - 5e-14 52.5 0.0 0.0024 18.3 0.0 4.3 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EMC98086.1 - 6.5e-07 29.6 0.0 2.9 8.3 0.0 4.5 4 1 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EMC98086.1 - 0.0023 18.0 0.0 0.1 12.7 0.0 3.1 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Arrestin_C PF02752.22 EMC98087.1 - 6e-21 75.3 0.0 2.1e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EMC98087.1 - 7.8e-07 29.3 0.0 0.00016 21.7 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Pro_isomerase PF00160.21 EMC98090.1 - 7.1e-47 159.6 0.0 1.3e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EMC98090.1 - 3.3e-05 24.0 0.0 0.00013 22.0 0.0 2.0 1 1 1 2 2 2 1 U-box domain zf-NOSIP PF15906.5 EMC98090.1 - 0.0031 17.6 0.0 0.0092 16.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 EMC98090.1 - 0.068 12.5 9.9 0.021 14.2 4.7 2.6 2 1 1 3 3 3 0 Rtf2 RING-finger PMSI1 PF15322.6 EMC98090.1 - 0.88 9.0 4.6 1.4 8.3 4.6 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Pentapeptide_4 PF13599.6 EMC98091.1 - 0.0001 22.4 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Crp PF00325.20 EMC98091.1 - 0.024 14.3 13.4 44 3.8 0.0 5.8 1 1 5 6 6 6 0 Bacterial regulatory proteins, crp family DUF211 PF02680.14 EMC98091.1 - 0.025 14.7 0.1 4.5 7.5 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 His_Phos_1 PF00300.22 EMC98092.1 - 9.4e-39 133.1 0.0 1.3e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CYTH PF01928.21 EMC98092.1 - 0.014 15.4 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 CYTH domain His_Phos_2 PF00328.22 EMC98092.1 - 0.18 11.1 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Tom22 PF04281.13 EMC98094.1 - 1.3e-51 174.0 1.3 1.4e-51 173.9 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Fungal_trans PF04082.18 EMC98094.1 - 0.13 11.3 0.1 0.15 11.1 0.1 1.3 1 1 0 1 1 1 0 Fungal specific transcription factor domain PQ-loop PF04193.14 EMC98095.1 - 2.4e-33 113.7 9.0 1.5e-16 59.9 0.4 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF676 PF05057.14 EMC98096.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EMC98096.1 - 0.0002 22.0 3.5 0.00029 21.5 3.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EMC98096.1 - 0.0014 18.4 0.1 0.0032 17.2 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EMC98096.1 - 0.002 17.5 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 EMC98096.1 - 0.0052 16.2 0.0 2.8 7.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 EMC98096.1 - 0.048 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 EMC98096.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 EMC98096.1 - 0.081 13.0 0.3 0.87 9.6 0.3 2.3 1 1 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 EMC98096.1 - 0.095 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1730 PF08331.10 EMC98096.1 - 0.18 11.7 0.0 0.53 10.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Dynamin_N PF00350.23 EMC98097.1 - 7.8e-17 61.8 0.0 7.8e-17 61.8 0.0 2.5 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EMC98097.1 - 4.2e-10 39.7 0.0 1.9e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2205 PF10224.9 EMC98097.1 - 3e-06 27.1 1.4 1.2e-05 25.2 1.4 2.0 1 0 0 1 1 1 1 Short coiled-coil protein GTP_EFTU PF00009.27 EMC98097.1 - 1e-05 25.1 3.6 0.0015 18.1 1.1 3.0 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EMC98097.1 - 0.033 14.7 0.0 0.72 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Citrate_ly_lig PF08218.11 EMC98097.1 - 0.059 13.0 0.2 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain IIGP PF05049.13 EMC98097.1 - 0.078 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) HRXXH PF13933.6 EMC98097.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase family SHQ1 PF04925.15 EMC98097.1 - 0.12 12.0 0.5 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 SHQ1 protein TsaE PF02367.17 EMC98097.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE USP8_dimer PF08969.11 EMC98097.1 - 0.34 11.1 3.0 4.2 7.6 0.1 3.6 3 0 0 3 3 3 0 USP8 dimerisation domain DLP_helical PF18709.1 EMC98097.1 - 0.46 9.6 3.9 1.5 8.0 0.6 2.2 2 0 0 2 2 2 0 Dynamin-like helical domain Spc7 PF08317.11 EMC98097.1 - 0.61 8.9 7.9 5.4 5.8 3.1 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Tweety PF04906.13 EMC98097.1 - 0.76 8.4 4.0 1.8 7.1 0.4 2.2 2 0 0 2 2 2 0 Tweety DUF1664 PF07889.12 EMC98097.1 - 2.2 8.4 4.4 38 4.3 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 EMC98097.1 - 2.3 8.3 8.1 0.8 9.8 3.2 2.7 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 SYF2 PF08231.12 EMC98097.1 - 3.5 8.0 8.8 3.1 8.2 0.3 3.4 4 0 0 4 4 4 0 SYF2 splicing factor 7TMR-HDED PF07697.11 EMC98097.1 - 9.3 6.3 11.1 13 5.8 0.5 3.2 3 0 0 3 3 3 0 7TM-HD extracellular Snf7 PF03357.21 EMC98098.1 - 6.9e-37 126.7 21.8 9.3e-37 126.3 21.3 1.4 2 0 0 2 2 2 1 Snf7 YlqD PF11068.8 EMC98098.1 - 0.026 14.9 23.4 2.3 8.6 9.7 2.1 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.15 EMC98098.1 - 0.14 11.7 8.2 0.2 11.2 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PMC2NT PF08066.12 EMC98098.1 - 0.39 11.4 2.7 5 7.9 0.3 2.4 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF4407 PF14362.6 EMC98098.1 - 1.3 8.3 8.9 1.9 7.8 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Remorin_C PF03763.13 EMC98098.1 - 2.3 8.1 12.3 0.63 9.9 8.8 1.9 1 1 1 2 2 2 0 Remorin, C-terminal region O-antigen_lig PF13425.6 EMC98098.1 - 3.1 6.5 5.2 3.8 6.2 5.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Chromate_transp PF02417.15 EMC98099.1 - 2.6e-57 193.4 40.6 2.2e-34 118.9 15.0 2.5 3 0 0 3 3 3 2 Chromate transporter PP2C PF00481.21 EMC98100.1 - 1.1e-63 215.3 0.1 1.3e-51 175.7 0.1 3.1 1 1 2 3 3 3 3 Protein phosphatase 2C CBS PF00571.28 EMC98101.1 - 8.9e-20 70.9 9.1 1.2e-07 32.1 0.1 3.8 4 0 0 4 4 4 3 CBS domain GDPD PF03009.17 EMC98102.1 - 6.3e-13 49.1 0.0 9e-13 48.5 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Methyltransf_25 PF13649.6 EMC98103.1 - 0.016 15.9 0.0 0.057 14.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EMC98103.1 - 0.043 14.5 0.0 0.26 12.0 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain CheR PF01739.18 EMC98103.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain COesterase PF00135.28 EMC98104.1 - 2.9e-64 217.8 0.0 8.1e-38 130.6 0.0 2.5 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC98104.1 - 0.0078 16.1 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFAP1 PF06991.11 EMC98105.1 - 9.1e-66 221.8 25.5 1.5e-65 221.1 25.5 1.3 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing PVL_ORF50 PF07768.11 EMC98105.1 - 4.1 7.8 9.6 0.79 10.1 3.9 2.3 2 0 0 2 2 2 0 PVL ORF-50-like family SNF2_N PF00176.23 EMC98107.1 - 6.7e-75 252.0 0.0 1.1e-74 251.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EMC98107.1 - 2.5e-21 75.4 0.0 5.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EMC98107.1 - 1.3e-15 57.6 0.0 3.1e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EMC98107.1 - 4.9e-05 23.1 8.2 9.6e-05 22.2 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC98107.1 - 6.5e-05 22.7 4.7 0.00014 21.6 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EMC98107.1 - 9.2e-05 22.3 0.0 0.00028 20.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 EMC98107.1 - 0.00018 21.8 8.4 0.00043 20.5 8.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMC98107.1 - 0.00026 20.8 6.1 0.00047 20.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EMC98107.1 - 0.00061 19.8 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PLU-1 PF08429.11 EMC98107.1 - 0.0019 17.4 0.5 0.0053 16.0 0.5 1.7 1 0 0 1 1 1 1 PLU-1-like protein ERCC3_RAD25_C PF16203.5 EMC98107.1 - 0.0021 17.3 0.0 0.0044 16.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_UBOX PF13445.6 EMC98107.1 - 0.0075 16.3 7.7 0.017 15.2 7.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMC98107.1 - 0.036 14.0 6.6 0.13 12.3 6.8 1.9 1 1 0 1 1 1 0 zinc-RING finger domain UBA_4 PF14555.6 EMC98107.1 - 0.07 13.0 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain DUF4788 PF16032.5 EMC98107.1 - 0.17 10.8 1.4 0.31 10.0 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) zf-ANAPC11 PF12861.7 EMC98107.1 - 0.42 10.7 2.6 0.98 9.5 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SQS_PSY PF00494.19 EMC98108.1 - 1.5e-52 178.7 0.1 2.2e-52 178.2 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase PrkA PF06798.12 EMC98108.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Sugar_tr PF00083.24 EMC98111.1 - 1e-77 262.0 17.4 1.2e-77 261.8 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC98111.1 - 6.9e-24 84.4 22.5 9.4e-22 77.4 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMC98111.1 - 4.6e-07 28.7 19.1 1.1e-05 24.2 2.9 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EMC98111.1 - 0.00039 19.0 3.1 0.00075 18.0 3.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COesterase PF00135.28 EMC98112.1 - 2.2e-70 238.0 0.0 2.8e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC98112.1 - 9e-08 32.2 0.2 1.7e-06 28.1 0.1 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC98112.1 - 0.04 13.4 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1992 PF09350.10 EMC98113.1 - 6.5e-21 74.3 0.2 1.8e-20 72.8 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) NfI_DNAbd_pre-N PF10524.9 EMC98116.1 - 0.037 13.9 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Clathrin_H_link PF13838.6 EMC98119.1 - 0.032 14.1 0.2 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Clathrin-H-link 2OG-FeII_Oxy PF03171.20 EMC98120.1 - 7.9e-14 52.0 0.0 1.9e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nitrate_red_del PF02613.15 EMC98121.1 - 0.066 13.2 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase delta subunit HOOK PF05622.12 EMC98121.1 - 0.15 10.2 0.0 0.16 10.0 0.0 1.0 1 0 0 1 1 1 0 HOOK protein 2_5_RNA_ligase2 PF13563.6 EMC98123.1 - 1.2e-10 41.4 0.1 1.6e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Abhydrolase_3 PF07859.13 EMC98124.1 - 6.2e-31 107.9 0.9 1e-30 107.2 0.9 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC98124.1 - 0.00046 19.2 0.0 0.0006 18.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EMC98124.1 - 0.099 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase MFS_1 PF07690.16 EMC98125.1 - 7.5e-36 123.8 26.5 1e-35 123.4 26.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cnn_1N PF07989.11 EMC98126.1 - 5.2e-07 29.7 7.9 1.6e-06 28.2 7.9 1.9 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 EMC98126.1 - 0.077 13.1 4.7 0.22 11.6 4.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 EMC98126.1 - 0.12 12.7 9.8 0.48 10.8 3.0 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain FlxA PF14282.6 EMC98126.1 - 0.27 11.2 5.9 0.043 13.8 0.8 2.4 2 0 0 2 2 2 0 FlxA-like protein Spc7 PF08317.11 EMC98126.1 - 0.46 9.3 9.1 0.86 8.4 9.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 EMC98126.1 - 3.2 7.8 5.1 12 6.0 0.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EMC98126.1 - 6.6 6.0 8.0 0.99 8.7 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) adh_short_C2 PF13561.6 EMC98127.1 - 4.7e-55 186.7 0.2 6e-55 186.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC98127.1 - 1.2e-45 155.4 0.6 1.7e-45 154.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC98127.1 - 4.3e-11 43.1 0.3 6.2e-11 42.5 0.3 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMC98127.1 - 0.018 14.5 0.0 0.04 13.3 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMC98127.1 - 0.074 12.5 0.1 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 EMC98128.1 - 1.5e-17 64.0 0.0 3.4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC98128.1 - 2.3e-15 57.1 0.0 6.2e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC98128.1 - 7e-14 51.9 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC98128.1 - 6.3e-12 45.6 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EMC98128.1 - 1.8e-11 43.9 0.0 2.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Sterol_MT_C PF08498.10 EMC98128.1 - 8.7e-11 42.0 0.1 2e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_12 PF08242.12 EMC98128.1 - 2.9e-08 34.4 0.0 1.3e-07 32.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC98128.1 - 4.4e-08 32.7 0.0 6.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EMC98128.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EMC98128.1 - 0.0024 17.5 0.0 0.0064 16.1 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 EMC98128.1 - 0.0093 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ADH_zinc_N PF00107.26 EMC98128.1 - 0.018 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DOT1 PF08123.13 EMC98128.1 - 0.077 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 EMC98128.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 EMC98128.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) COX6A PF02046.15 EMC98129.1 - 6.6e-47 158.6 0.2 7.6e-47 158.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa F-box-like PF12937.7 EMC98130.1 - 4.6e-08 32.8 1.9 8.3e-08 32.0 0.9 2.1 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.16 EMC98131.1 - 9.2e-31 107.0 41.1 6.5e-30 104.2 41.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Jiraiya PF15038.6 EMC98131.1 - 0.36 10.3 7.4 7.2 6.0 0.9 2.9 3 0 0 3 3 3 0 Jiraiya DUF4579 PF15158.6 EMC98131.1 - 3.1 7.5 5.1 0.68 9.7 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) BTP PF05232.12 EMC98131.1 - 3.7 7.7 9.3 0.17 12.0 1.4 3.0 3 0 0 3 3 3 0 Chlorhexidine efflux transporter FMN_dh PF01070.18 EMC98132.1 - 3.9e-106 355.0 0.2 5.3e-106 354.6 0.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EMC98132.1 - 4e-18 65.3 0.1 8.3e-18 64.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ThiG PF05690.14 EMC98132.1 - 5.9e-06 25.8 1.4 0.0024 17.2 0.0 3.1 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EMC98132.1 - 0.00079 18.5 1.5 0.012 14.7 0.2 2.8 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMC98132.1 - 0.001 18.3 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EMC98132.1 - 0.0016 17.9 0.1 0.0023 17.4 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Dus PF01207.17 EMC98132.1 - 0.018 14.2 0.1 0.046 12.8 0.1 1.8 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF4627 PF15425.6 EMC98132.1 - 0.07 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4627) TMP-TENI PF02581.17 EMC98132.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase PFU PF09070.11 EMC98133.1 - 3.9e-05 23.9 0.3 8.2e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BTB PF00651.31 EMC98134.1 - 8.8e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain S4 PF01479.25 EMC98135.1 - 2.5e-11 43.1 0.8 2.5e-11 43.1 0.8 2.6 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EMC98135.1 - 6.7e-06 26.9 0.4 1.4e-05 25.9 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 EMC98135.1 - 0.078 13.1 0.5 3.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L21e PF01157.18 EMC98137.1 - 1.1e-46 156.8 3.7 1.1e-46 156.8 3.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e LRIF1 PF15741.5 EMC98137.1 - 0.021 13.4 0.4 0.024 13.2 0.4 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF5486 PF17588.2 EMC98137.1 - 0.2 11.6 1.4 0.42 10.5 1.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Atg29_N PF18388.1 EMC98138.1 - 2.6e-24 84.8 0.7 4.5e-24 84.0 0.7 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain DUP PF00674.18 EMC98138.1 - 0.23 11.6 0.0 0.36 11.0 0.0 1.2 1 0 0 1 1 1 0 DUP family TFIIF_alpha PF05793.12 EMC98138.1 - 5.7 5.4 9.2 13 4.3 9.2 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) OPT PF03169.15 EMC98140.1 - 9e-89 298.8 44.8 1e-88 298.5 44.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein zf-RING_UBOX PF13445.6 EMC98141.1 - 2.2e-08 34.0 1.1 2.2e-08 34.0 1.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMC98141.1 - 6.5e-07 29.1 4.1 9.3e-06 25.4 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC98141.1 - 7.6e-07 28.9 7.1 1.3e-06 28.2 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC98141.1 - 3.3e-06 26.9 5.8 6.7e-06 26.0 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EMC98141.1 - 4.4e-06 26.9 7.0 0.00023 21.4 8.3 2.2 1 1 1 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 EMC98141.1 - 2.4e-05 24.4 1.6 2.4e-05 24.4 1.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EMC98141.1 - 6.9e-05 22.6 8.2 0.00022 21.0 8.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC98141.1 - 0.014 15.3 8.2 0.13 12.2 8.3 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TerY_C PF15616.6 EMC98141.1 - 0.059 13.5 0.5 0.14 12.3 0.5 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_10 PF16685.5 EMC98141.1 - 0.064 13.4 1.0 0.15 12.2 1.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EMC98141.1 - 0.38 10.5 5.4 3.3 7.5 3.4 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 EMC98141.1 - 1 9.7 6.2 3.3 8.1 6.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain PRP1_N PF06424.12 EMC98141.1 - 3 8.3 6.1 0.4 11.1 1.1 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Lar_restr_allev PF14354.6 EMC98141.1 - 6.4 7.2 7.1 1 9.8 2.0 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar MFS_1 PF07690.16 EMC98142.1 - 6.2e-36 124.0 27.9 4.8e-27 94.8 10.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98142.1 - 2.4e-11 43.2 8.0 2.4e-11 43.2 8.0 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EMC98142.1 - 0.00065 18.2 3.2 0.0011 17.4 3.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RhoGAP PF00620.27 EMC98143.1 - 2.3e-40 137.9 0.0 6.4e-40 136.4 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EMC98143.1 - 6e-09 36.1 0.3 6e-09 36.1 0.3 2.2 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain Cys_Met_Meta_PP PF01053.20 EMC98143.1 - 0.15 10.6 0.0 0.34 9.4 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Rsm22 PF09243.10 EMC98144.1 - 3.2e-30 105.3 0.0 2.2e-21 76.4 0.0 3.1 3 1 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Pkinase PF00069.25 EMC98145.1 - 2.4e-26 92.7 0.0 3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC98145.1 - 6.7e-14 51.8 0.0 9.2e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMC98145.1 - 4.3e-09 35.6 0.0 6.3e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EMC98145.1 - 0.00019 21.5 0.0 0.0014 18.6 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family DASH_Spc19 PF08287.11 EMC98147.1 - 8e-52 175.3 6.6 1e-51 175.0 6.6 1.1 1 0 0 1 1 1 1 Spc19 UPF0184 PF03670.13 EMC98147.1 - 0.12 12.8 0.6 0.23 11.9 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) SH3_1 PF00018.28 EMC98149.1 - 2.2e-05 23.9 0.0 5.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMC98149.1 - 0.039 13.8 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain zf-CCCH PF00642.24 EMC98150.1 - 0.00011 22.0 2.5 0.00019 21.2 2.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EMC98150.1 - 0.0023 17.9 2.3 0.0037 17.3 2.3 1.3 1 0 0 1 1 1 1 Zinc finger domain Spc7 PF08317.11 EMC98150.1 - 0.0046 15.9 8.7 0.0076 15.2 8.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein CBM_X2 PF03442.14 EMC98150.1 - 0.038 14.1 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Fez1 PF06818.15 EMC98150.1 - 0.07 13.6 8.3 0.11 13.0 8.3 1.4 1 0 0 1 1 1 0 Fez1 KxDL PF10241.9 EMC98150.1 - 0.091 13.0 4.8 0.061 13.6 2.2 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein Prefoldin_3 PF13758.6 EMC98150.1 - 0.12 12.4 2.1 12 6.1 0.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit Spectrin PF00435.21 EMC98150.1 - 0.14 12.7 11.0 1.8 9.1 5.9 3.0 1 1 2 3 3 3 0 Spectrin repeat SlyX PF04102.12 EMC98150.1 - 0.14 12.8 11.8 11 6.7 0.0 4.2 3 1 1 4 4 4 0 SlyX AAA_13 PF13166.6 EMC98150.1 - 0.22 10.1 7.0 0.29 9.7 7.0 1.2 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.11 EMC98150.1 - 0.37 11.2 4.5 4.8 7.7 0.2 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Het-C PF07217.11 EMC98150.1 - 0.39 9.2 4.6 0.54 8.7 4.6 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF4407 PF14362.6 EMC98150.1 - 0.51 9.6 14.5 2 7.7 9.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) XhlA PF10779.9 EMC98150.1 - 0.89 9.8 7.8 14 5.9 0.4 3.2 2 1 1 3 3 3 0 Haemolysin XhlA Fib_alpha PF08702.10 EMC98150.1 - 0.99 9.6 5.9 0.87 9.8 2.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 EMC98150.1 - 1.3 8.9 13.0 0.21 11.4 1.8 3.3 2 1 1 3 3 3 0 Septum formation initiator DUF3138 PF11336.8 EMC98150.1 - 1.7 7.2 5.2 2.3 6.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) V_ATPase_I PF01496.19 EMC98150.1 - 2.3 6.0 4.6 2.7 5.8 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 EMC98150.1 - 2.3 8.3 12.8 1.6 8.8 9.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 EMC98150.1 - 2.8 8.5 8.2 5 7.7 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 FadA PF09403.10 EMC98150.1 - 2.9 8.4 8.7 1.2 9.7 4.8 2.2 2 1 1 3 3 2 0 Adhesion protein FadA UPF0242 PF06785.11 EMC98150.1 - 4.6 7.3 10.7 0.98 9.5 3.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 EMC98150.1 - 5.1 6.1 9.1 14 4.7 8.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 EMC98150.1 - 5.4 7.1 7.8 0.64 10.1 3.0 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 EMC98150.1 - 5.4 7.5 14.1 6.7 7.2 10.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 EMC98150.1 - 6.9 6.7 7.0 7 6.7 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EMC98150.1 - 8.5 6.9 9.1 33 5.0 5.4 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Uso1_p115_C PF04871.13 EMC98150.1 - 9.4 6.6 14.3 25 5.2 14.3 1.7 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Allexi_40kDa PF05549.11 EMC98150.1 - 9.6 5.6 10.0 3 7.3 3.9 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Ribonuc_red_sm PF00268.21 EMC98151.1 - 8.5e-121 402.7 1.3 1.1e-120 402.4 1.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain WD40 PF00400.32 EMC98152.1 - 4.3e-15 55.8 1.2 8.8e-09 35.9 0.2 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC98152.1 - 7.4e-07 29.4 0.0 0.4 11.0 0.0 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WDCP PF15390.6 EMC98152.1 - 0.027 12.9 0.0 0.074 11.4 0.0 1.6 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family Cytochrom_D1 PF02239.16 EMC98152.1 - 0.033 12.7 0.0 5.6 5.4 0.0 2.7 3 0 0 3 3 3 0 Cytochrome D1 heme domain Frtz PF11768.8 EMC98152.1 - 0.047 12.0 0.0 0.12 10.7 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Herpes_UL37_1 PF03970.13 EMC98152.1 - 0.07 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein Mito_carr PF00153.27 EMC98153.1 - 3.6e-53 177.4 1.5 6.5e-18 64.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1751 PF08551.10 EMC98154.1 - 0.00083 19.9 1.0 0.00083 19.9 1.0 2.0 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EMC98154.1 - 0.05 13.6 1.4 0.092 12.7 1.4 1.6 1 1 0 1 1 1 0 Rhomboid family PI3K_1B_p101 PF10486.9 EMC98157.1 - 0.51 8.1 2.1 0.77 7.5 2.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apc13p PF05839.11 EMC98157.1 - 1.2 9.4 4.8 21 5.4 0.1 2.7 2 0 0 2 2 2 0 Apc13p protein SNARE PF05739.19 EMC98158.1 - 1e-11 44.6 0.1 2.4e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EMC98158.1 - 9.7e-10 37.4 0.5 2.3e-09 36.2 0.5 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 EMC98158.1 - 5.9e-05 22.8 3.6 0.0016 18.2 0.2 2.5 2 1 0 2 2 2 1 Syntaxin Syntaxin-18_N PF10496.9 EMC98158.1 - 0.072 13.3 0.2 0.87 9.9 0.0 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus LXG PF04740.12 EMC98158.1 - 0.15 11.8 2.7 0.15 11.8 0.5 2.1 2 1 0 2 2 2 0 LXG domain of WXG superfamily SlyX PF04102.12 EMC98158.1 - 0.23 12.1 0.3 0.23 12.1 0.3 3.4 4 0 0 4 4 4 0 SlyX DUF1664 PF07889.12 EMC98158.1 - 0.31 11.1 2.0 2.1 8.4 0.2 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EMC98158.1 - 0.71 10.2 3.3 1.7 9.0 0.0 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 EMC98158.1 - 0.81 10.2 5.8 0.54 10.8 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-C4H2 PF10146.9 EMC98158.1 - 1.6 9.0 3.7 10 6.4 0.1 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein Prominin PF05478.11 EMC98158.1 - 3.2 5.6 4.2 6.1 4.7 0.8 2.2 2 1 0 2 2 2 0 Prominin Spc7 PF08317.11 EMC98158.1 - 9.5 5.0 8.2 3.8 6.3 1.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Acatn PF13000.7 EMC98159.1 - 2.6e-164 547.7 17.5 9.6e-83 278.5 6.1 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 EMC98159.1 - 0.00095 18.1 7.5 0.00095 18.1 7.5 2.0 2 0 0 2 2 2 1 MFS_1 like family Yae1_N PF09811.9 EMC98161.1 - 2.8e-13 49.3 3.6 5e-13 48.5 3.6 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal MFS_1 PF07690.16 EMC98162.1 - 2.1e-24 86.1 63.6 1e-16 60.9 37.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SAICAR_synt PF01259.18 EMC98163.1 - 2.2e-98 328.9 0.0 2.5e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase ANAPC5 PF12862.7 EMC98164.1 - 2.1e-30 104.6 2.9 4.3e-30 103.6 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 Exo_endo_phos PF03372.23 EMC98165.1 - 2.8e-10 40.1 0.1 1.2e-09 38.0 0.1 2.1 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EMC98165.1 - 0.00024 21.1 1.7 0.00058 19.9 1.7 1.7 1 0 0 1 1 1 1 GRF zinc finger Nyv1_N PF09426.10 EMC98165.1 - 0.081 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal HMG_box PF00505.19 EMC98166.1 - 8e-24 83.8 0.6 1e-23 83.5 0.6 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EMC98166.1 - 1.4e-05 25.6 0.4 1.7e-05 25.3 0.4 1.1 1 0 0 1 1 1 1 HMG-box domain DUF789 PF05623.12 EMC98166.1 - 0.009 15.7 0.1 0.009 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF789) MATalpha_HMGbox PF04769.12 EMC98166.1 - 0.032 13.6 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DUF3079 PF11278.8 EMC98169.1 - 0.11 12.3 0.8 0.14 11.9 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3079) MMM1 PF10296.9 EMC98171.1 - 2.1e-05 23.8 1.4 2.1e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 EMC98171.1 - 0.088 13.2 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Abhydrolase_1 PF00561.20 EMC98172.1 - 1.7e-14 54.1 0.2 4.9e-14 52.6 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC98172.1 - 2.5e-10 40.0 0.2 0.00041 19.7 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMC98172.1 - 0.015 14.8 0.9 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EMC98172.1 - 0.017 14.9 0.2 0.079 12.8 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 EMC98172.1 - 0.18 11.7 0.1 3.6 7.4 0.1 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3433 PF11915.8 EMC98173.1 - 4.1e-34 116.9 13.3 1.3e-25 89.7 2.0 3.8 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) DEAD PF00270.29 EMC98174.1 - 2.7e-44 151.0 0.0 5.2e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC98174.1 - 7.8e-27 93.8 0.0 6.7e-26 90.8 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC98174.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EMC98174.1 - 0.012 14.4 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain HSP70 PF00012.20 EMC98175.1 - 2.2e-71 240.8 0.9 3.1e-71 240.4 0.9 1.2 1 0 0 1 1 1 1 Hsp70 protein PilM_2 PF11104.8 EMC98175.1 - 0.00016 20.8 0.0 0.07 12.1 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; DUF3246 PF11596.8 EMC98175.1 - 0.029 13.8 0.9 0.061 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) FAM176 PF14851.6 EMC98175.1 - 0.26 11.0 1.6 0.56 9.9 1.6 1.5 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 EMC98175.1 - 0.27 11.3 1.7 0.56 10.2 1.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EMC98175.1 - 0.45 10.9 9.0 1 9.8 9.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 EMC98175.1 - 1 8.4 7.1 1.7 7.7 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.6 EMC98175.1 - 2.4 8.6 9.0 2 8.8 6.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 EMC98175.1 - 3.5 6.9 8.7 5.7 6.2 8.7 1.2 1 0 0 1 1 1 0 NOA36 protein KH_6 PF15985.5 EMC98176.1 - 2.2e-16 59.9 0.3 3.8e-16 59.2 0.3 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EMC98176.1 - 8.1e-11 41.7 2.0 1.4e-10 40.9 0.5 2.1 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain Ion_trans_2 PF07885.16 EMC98179.1 - 3.7e-31 106.9 23.9 9.7e-18 63.9 5.5 3.4 3 0 0 3 3 3 2 Ion channel NPCC PF08058.11 EMC98179.1 - 0.089 12.8 0.1 2.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Nuclear pore complex component DUF5362 PF17319.2 EMC98179.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5362) Polyketide_cyc PF03364.20 EMC98180.1 - 2.9e-07 30.8 0.0 1.4e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EMC98180.1 - 0.028 14.7 0.9 0.14 12.4 0.0 2.1 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport 5_3_exonuc PF01367.20 EMC98180.1 - 0.14 12.7 0.3 0.29 11.8 0.3 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold PIG-L PF02585.17 EMC98182.1 - 7.5e-25 88.1 0.0 1.1e-24 87.5 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Chs7 PF12271.8 EMC98183.1 - 6.5e-122 406.4 20.6 7.5e-122 406.2 20.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone PGP_phosphatase PF09419.10 EMC98185.1 - 2e-65 219.5 0.0 2.2e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EMC98185.1 - 5.7e-08 32.7 0.0 1.8e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 HAD-hyrolase-like DUF2755 PF10954.8 EMC98185.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) Rhomboid PF01694.22 EMC98186.1 - 3.7e-34 117.9 9.4 3.7e-34 117.9 9.4 1.8 2 0 0 2 2 2 1 Rhomboid family TssN PF17555.2 EMC98186.1 - 1.2 8.5 4.8 2 7.7 4.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN vWA-TerF-like PF10138.9 EMC98187.1 - 1.2e-08 35.4 0.1 1.7e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EMC98187.1 - 0.00092 19.5 0.1 0.0016 18.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Pro_racemase PF05544.11 EMC98187.1 - 0.022 13.8 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Proline racemase GhoS PF11080.8 EMC98187.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease GhoS PseudoU_synth_2 PF00849.22 EMC98188.1 - 1e-30 107.0 0.0 1.5e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.12 EMC98188.1 - 0.014 15.5 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) S4 PF01479.25 EMC98188.1 - 0.082 12.6 0.3 0.082 12.6 0.3 2.1 2 0 0 2 2 2 0 S4 domain Sugar_tr PF00083.24 EMC98190.1 - 3.2e-69 234.0 20.2 3.6e-69 233.8 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC98190.1 - 4.4e-25 88.4 29.2 5.4e-25 88.1 29.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyridoxal_deC PF00282.19 EMC98191.1 - 7.8e-106 353.9 0.0 1e-105 353.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EMC98191.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SepSecS PF05889.13 EMC98191.1 - 0.074 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Tyr-DNA_phospho PF06087.12 EMC98192.1 - 4.1e-86 289.5 0.0 4.9e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EMC98192.1 - 0.0051 16.7 0.0 0.061 13.2 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain WD40 PF00400.32 EMC98193.1 - 3.9e-17 62.3 4.7 0.00027 21.6 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC98193.1 - 5.8e-05 23.3 0.1 1.1 9.6 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Met_asp_mut_E PF06368.11 EMC98193.1 - 0.14 10.6 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) S1 PF00575.23 EMC98194.1 - 1.4e-66 220.8 21.1 6.1e-15 55.3 0.2 11.4 12 0 0 12 12 12 8 S1 RNA binding domain Suf PF05843.14 EMC98194.1 - 1.8e-06 28.2 15.1 0.0058 16.7 0.0 4.2 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EMC98194.1 - 0.0015 19.2 8.0 0.82 10.7 0.0 5.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMC98194.1 - 0.0044 17.5 0.1 5.9 7.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EMC98194.1 - 0.0076 16.2 15.0 2.5 8.1 0.1 6.8 7 0 0 7 7 7 2 RNase II-type exonuclease C-terminal S1 domain S1_2 PF13509.6 EMC98194.1 - 0.054 13.6 0.2 3.4 7.8 0.0 3.8 4 0 0 4 4 4 0 S1 domain PSD4 PF07631.11 EMC98194.1 - 0.51 10.9 2.5 0.72 10.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) Abhydrolase_6 PF12697.7 EMC98195.1 - 2.6e-09 38.0 1.6 4.1e-09 37.4 1.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMC98195.1 - 4.9e-07 29.3 0.0 7.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMC98195.1 - 0.053 13.0 0.1 1.2 8.6 0.2 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Polysacc_synt_2 PF02719.15 EMC98196.1 - 0.11 11.6 0.4 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein BST2 PF16716.5 EMC98196.1 - 0.67 10.6 2.5 1.7 9.3 0.4 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Ran_BP1 PF00638.18 EMC98197.1 - 9.8e-49 164.7 1.0 1.6e-48 164.0 1.0 1.3 1 0 0 1 1 1 1 RanBP1 domain VID27_PH PF17747.1 EMC98197.1 - 0.00016 22.0 0.0 0.00024 21.4 0.0 1.3 1 0 0 1 1 1 1 VID27 PH-like domain WH1 PF00568.23 EMC98197.1 - 0.00022 21.1 0.2 0.0019 18.1 0.2 2.2 1 1 0 1 1 1 1 WH1 domain RPN2_C PF18004.1 EMC98197.1 - 0.85 9.5 9.4 1.4 8.8 9.4 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC27 PF09507.10 EMC98197.1 - 6.5 6.0 18.8 9.1 5.6 18.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 YEATS PF03366.16 EMC98198.1 - 5.1e-16 58.4 0.0 1.2e-15 57.2 0.0 1.6 2 0 0 2 2 2 1 YEATS family BET PF17035.5 EMC98198.1 - 2.3e-05 24.5 0.4 4.1e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation SLX9 PF15341.6 EMC98198.1 - 0.028 14.8 0.7 0.052 13.9 0.7 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 zf-rbx1 PF12678.7 EMC98199.1 - 6.5e-11 42.4 0.3 1.2e-10 41.5 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EMC98199.1 - 2.8e-09 37.2 2.6 2.1e-08 34.4 0.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EMC98199.1 - 6.8e-08 32.3 0.4 1.3e-07 31.5 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EMC98199.1 - 9.5e-08 31.8 0.4 1.7e-07 30.9 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC98199.1 - 1.5e-06 27.9 5.4 1e-05 25.2 1.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC98199.1 - 2e-06 27.7 0.2 3.5e-05 23.7 0.0 2.8 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EMC98199.1 - 3.7e-05 23.5 1.5 3.9e-05 23.4 0.3 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EMC98199.1 - 0.00049 19.9 1.0 0.00049 19.9 1.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMC98199.1 - 0.0009 18.9 8.1 0.007 16.1 0.5 3.1 3 0 0 3 3 3 2 RING-like zinc finger Zn_ribbon_17 PF17120.5 EMC98199.1 - 0.0016 18.0 0.5 0.0035 16.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF2921 PF11145.8 EMC98199.1 - 0.012 13.5 3.2 0.026 12.4 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2921) zf-ANAPC11 PF12861.7 EMC98199.1 - 0.017 15.2 0.9 0.017 15.2 0.9 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EMC98199.1 - 0.2 11.8 2.4 0.67 10.2 2.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EMC98199.1 - 7 6.9 5.5 0.89 9.7 1.1 1.8 2 0 0 2 2 2 0 RING-variant domain Complex1_LYR PF05347.15 EMC98201.1 - 4.1e-19 68.4 6.8 5.8e-19 67.9 6.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EMC98201.1 - 6.8e-07 29.9 2.9 7.8e-07 29.8 2.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EMC98201.1 - 0.007 16.9 0.6 0.0079 16.8 0.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like VitD-bind_III PF09164.10 EMC98201.1 - 0.15 12.0 0.3 0.26 11.3 0.3 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III SUR7 PF06687.12 EMC98202.1 - 8.1e-26 91.0 13.8 1.1e-25 90.5 13.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.6 EMC98202.1 - 0.15 12.5 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 SCIMP protein DUF4175 PF13779.6 EMC98202.1 - 0.19 9.6 1.3 0.29 9.0 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PalH PF08733.10 EMC98202.1 - 0.65 8.9 5.2 0.92 8.5 5.2 1.2 1 0 0 1 1 1 0 PalH/RIM21 FMO-like PF00743.19 EMC98203.1 - 3.9e-23 81.7 0.0 8.9e-23 80.5 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMC98203.1 - 1.5e-15 57.3 0.0 3.3e-14 52.8 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC98203.1 - 1.2e-11 44.4 0.0 1.3e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC98203.1 - 2.2e-10 40.2 0.0 7.1e-09 35.2 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EMC98203.1 - 1.1e-06 28.8 0.5 5.5e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC98203.1 - 3.4e-05 24.3 1.2 0.15 12.6 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC98203.1 - 0.00072 19.2 1.0 0.00072 19.2 1.0 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EMC98203.1 - 0.0027 17.8 0.0 0.56 10.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EMC98203.1 - 0.0028 17.0 0.1 0.4 9.9 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EMC98203.1 - 0.025 14.5 0.9 1.4 8.9 0.1 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EMC98203.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EMC98203.1 - 0.15 12.5 0.0 0.55 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EMC98203.1 - 0.33 10.0 1.6 0.55 9.2 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain LOR PF04525.12 EMC98205.1 - 3.4e-13 49.6 0.0 4.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related DUF948 PF06103.11 EMC98206.1 - 0.48 10.7 4.9 1.6 9.0 0.5 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) RRM_1 PF00076.22 EMC98207.1 - 5.1e-61 202.4 0.0 4.2e-21 74.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMC98207.1 - 2.5e-09 36.8 0.0 7.2e-05 22.4 0.0 3.5 2 1 2 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC98207.1 - 4.6e-08 32.8 0.0 0.012 15.5 0.0 3.6 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_8 PF11835.8 EMC98207.1 - 5.6e-05 23.3 0.0 0.076 13.2 0.0 2.5 2 0 0 2 2 2 2 RRM-like domain Nup35_RRM_2 PF14605.6 EMC98207.1 - 8.2e-05 22.5 0.1 2.1 8.4 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 EMC98207.1 - 0.00063 19.8 0.0 0.79 9.8 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 EMC98207.1 - 0.00066 19.7 0.3 1.5 9.0 0.0 3.3 3 2 1 4 4 4 2 RNA recognition motif rve PF00665.26 EMC98207.1 - 0.045 14.0 0.0 2.6 8.2 0.0 2.6 3 0 0 3 3 3 0 Integrase core domain SH3_16 PF18348.1 EMC98207.1 - 0.07 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain RRM_3 PF08777.11 EMC98207.1 - 0.16 12.0 0.0 3.6 7.7 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif DUF2802 PF10975.8 EMC98207.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) POT1PC PF16686.5 EMC98208.1 - 7.8e-42 142.8 0.2 1e-40 139.2 0.1 2.4 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EMC98208.1 - 2.5e-21 76.0 0.0 6.7e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Arm PF00514.23 EMC98209.1 - 1.4e-96 313.9 13.7 4.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EMC98209.1 - 7e-28 96.9 0.6 1.8e-27 95.6 0.6 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 EMC98209.1 - 3.1e-23 81.1 1.6 7.6e-23 79.8 1.6 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 EMC98209.1 - 8.9e-22 77.2 11.3 1.5e-09 38.2 0.1 6.6 6 1 1 7 7 7 4 HEAT-like repeat HEAT_2 PF13646.6 EMC98209.1 - 1.8e-21 76.3 0.2 2.6e-09 37.3 0.1 5.2 1 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 EMC98209.1 - 6e-20 69.6 1.1 3.5e-06 26.8 0.0 7.4 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 EMC98209.1 - 1.1e-08 34.8 0.0 0.022 14.2 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 EMC98209.1 - 2.3e-06 26.5 0.0 0.00027 19.7 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 EMC98209.1 - 6.4e-05 23.0 0.0 1.4 9.0 0.0 4.5 3 2 2 5 5 5 2 V-ATPase subunit H NopRA1 PF16201.5 EMC98209.1 - 0.0011 18.5 0.0 0.73 9.4 0.0 3.9 2 1 2 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 EMC98209.1 - 0.0022 18.2 4.2 0.88 9.9 0.0 5.1 3 2 3 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.7 EMC98209.1 - 0.0029 17.6 0.0 5.6 7.0 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EMC98209.1 - 0.031 14.9 7.9 0.56 11.0 0.2 5.0 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat NUSAP PF16006.5 EMC98209.1 - 2.2 8.0 6.0 3 7.5 6.0 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein YjeF_N PF03853.15 EMC98210.1 - 3.5e-25 88.8 0.2 5.4e-25 88.2 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EMC98210.1 - 8.3e-08 33.1 0.8 8.3e-08 33.1 0.8 2.4 1 1 1 2 2 2 1 FDF domain DASH_Spc19 PF08287.11 EMC98211.1 - 0.008 16.1 0.4 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 Spc19 ATP-synt_D PF01813.17 EMC98211.1 - 0.022 14.6 1.1 0.18 11.6 1.1 2.0 1 1 0 1 1 1 0 ATP synthase subunit D BRE1 PF08647.11 EMC98211.1 - 0.033 14.2 3.0 0.17 11.9 0.3 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FliJ PF02050.16 EMC98211.1 - 0.11 12.7 3.6 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein TMF_DNA_bd PF12329.8 EMC98211.1 - 0.29 11.2 2.3 1.5 8.9 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Glyco_hydro_9 PF00759.19 EMC98212.1 - 1.4e-94 317.9 13.7 1.9e-94 317.4 13.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CelD_N PF02927.14 EMC98212.1 - 1.4e-23 83.6 0.4 3e-23 82.5 0.1 1.8 2 0 0 2 2 2 1 Cellulase N-terminal ig-like domain Myb_DNA-binding PF00249.31 EMC98213.1 - 2e-16 59.9 0.6 3.7e-08 33.4 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC98213.1 - 9.7e-14 51.4 0.0 8.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EMC98213.1 - 2.5e-05 24.2 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EMC98213.1 - 0.056 13.7 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Phosducin PF02114.16 EMC98214.1 - 6e-12 45.1 0.0 8e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Phosducin HECT PF00632.25 EMC98215.1 - 1.6e-80 270.9 0.0 2.3e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EMC98215.1 - 0.00092 18.8 1.7 0.0045 16.7 1.7 2.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif MFS_1 PF07690.16 EMC98216.1 - 4.3e-21 75.2 37.4 4.3e-21 75.2 37.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Prenyltransf PF01255.19 EMC98217.1 - 1.7e-69 233.8 6.1 1.5e-68 230.7 6.1 1.9 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Flagellar_rod PF05149.12 EMC98217.1 - 0.1 12.1 0.4 0.14 11.6 0.4 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein Peptidase_M29 PF02073.15 EMC98217.1 - 0.18 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Alpha-amylase PF00128.24 EMC98218.1 - 3.1e-19 69.7 2.8 1.1e-18 67.9 2.8 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EMC98218.1 - 3.5e-15 56.4 0.0 7.1e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EMC98218.1 - 6.1e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EMC98218.1 - 0.0093 16.0 0.1 0.035 14.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Suc_Fer-like PF06999.12 EMC98219.1 - 1.1e-69 234.2 0.0 1.4e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer4_13 PF13370.6 EMC98219.1 - 0.1 13.1 0.1 0.33 11.5 0.1 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I P22_Cro PF14549.6 EMC98220.1 - 0.1 12.5 0.3 0.76 9.7 0.1 2.3 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro REPA_OB_2 PF16900.5 EMC98220.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Replication protein A OB domain Acetyltransf_1 PF00583.25 EMC98221.1 - 6.8e-05 23.1 0.1 0.00011 22.4 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EMC98221.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 EMC98221.1 - 0.015 15.7 0.1 0.03 14.7 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC98221.1 - 0.059 13.3 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC98221.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein ADH_zinc_N PF00107.26 EMC98222.1 - 5.2e-12 45.9 0.0 1.6e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC98222.1 - 3.6e-06 26.8 0.1 0.0003 20.6 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMC98222.1 - 0.0091 17.0 0.0 0.027 15.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PH_10 PF15411.6 EMC98223.1 - 2.5e-38 131.1 0.0 6e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EMC98223.1 - 4.5e-31 107.0 0.0 1e-30 105.8 0.0 1.6 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 EMC98223.1 - 9.6e-29 100.9 0.8 1.5e-28 100.3 0.8 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EMC98223.1 - 1e-05 25.4 0.0 6e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 PB1 domain PH PF00169.29 EMC98223.1 - 0.0025 18.3 0.0 0.0055 17.2 0.0 1.6 1 0 0 1 1 1 1 PH domain WD40 PF00400.32 EMC98225.1 - 7.4e-28 96.2 21.2 1.4e-05 25.8 0.2 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 EMC98225.1 - 5.4e-11 42.2 1.9 1e-10 41.4 0.8 2.0 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 EMC98225.1 - 4.2e-08 33.4 0.1 0.091 13.1 0.0 3.8 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EMC98225.1 - 3.2e-07 30.1 0.2 8.9e-07 28.6 0.2 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EMC98225.1 - 1.7e-05 23.7 1.5 0.45 9.1 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EMC98225.1 - 0.031 13.2 0.0 0.098 11.6 0.0 1.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain LemA PF04011.12 EMC98226.1 - 0.0032 17.3 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 LemA family ING PF12998.7 EMC98226.1 - 0.057 14.0 0.1 21 5.8 0.0 2.7 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DHR10 PF18595.1 EMC98226.1 - 0.16 12.1 2.8 0.3 11.1 0.7 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain WD40 PF00400.32 EMC98227.1 - 1.3e-54 180.9 9.5 1.2e-09 38.6 1.4 8.7 7 3 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC98227.1 - 3.3e-15 56.1 0.1 9.5e-06 25.8 0.0 4.7 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC98227.1 - 5.2e-05 22.1 0.4 0.0051 15.5 0.1 3.3 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EMC98227.1 - 0.00015 20.6 0.2 1.1 7.9 0.1 3.8 3 1 0 3 3 3 3 Nup133 N terminal like VID27 PF08553.10 EMC98227.1 - 0.0021 17.2 0.0 0.0043 16.2 0.0 1.4 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain CLASP_N PF12348.8 EMC98228.1 - 0.00054 19.6 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 EMC98228.1 - 0.002 18.2 0.4 11 6.6 0.3 3.9 3 0 0 3 3 3 0 HEAT repeat Fez1 PF06818.15 EMC98228.1 - 0.0034 17.8 4.1 0.0034 17.8 4.1 1.9 2 0 0 2 2 2 1 Fez1 FapA PF03961.13 EMC98228.1 - 0.17 10.4 0.6 0.35 9.4 0.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Leu_zip PF15294.6 EMC98228.1 - 0.19 11.2 10.2 0.065 12.7 7.3 1.6 2 0 0 2 2 2 0 Leucine zipper Golgin_A5 PF09787.9 EMC98228.1 - 0.42 10.0 11.6 0.88 9.0 11.6 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF724 PF05266.14 EMC98228.1 - 0.45 10.3 4.3 0.94 9.3 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Syntaxin PF00804.25 EMC98228.1 - 0.68 9.6 9.0 0.057 13.1 3.8 1.9 2 0 0 2 2 2 0 Syntaxin Mod_r PF07200.13 EMC98228.1 - 0.83 9.8 14.7 6.9 6.8 5.2 3.8 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 EMC98228.1 - 1.2 9.3 8.6 5.1 7.3 0.4 3.0 2 0 0 2 2 2 0 bZIP transcription factor BRE1 PF08647.11 EMC98228.1 - 1.2 9.2 11.0 4.2 7.5 6.2 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HAUS-augmin3 PF14932.6 EMC98228.1 - 1.4 8.4 10.5 5 6.6 10.5 1.9 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Atg14 PF10186.9 EMC98228.1 - 2.5 7.1 8.2 5.1 6.1 8.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bap31_Bap29_C PF18035.1 EMC98228.1 - 2.7 8.1 6.6 1.8 8.6 2.6 2.6 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 EMC98228.1 - 3.5 7.9 10.6 7.5 6.9 3.2 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc24 PF08286.11 EMC98228.1 - 4.1 7.7 12.1 4 7.7 1.2 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 EMC98228.1 - 5 5.9 11.3 13 4.6 11.3 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4559 PF15112.6 EMC98228.1 - 8.9 5.9 9.1 1.7 8.3 4.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) DUF1100 PF06500.11 EMC98230.1 - 4e-12 45.7 0.0 4.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 EMC98230.1 - 5e-06 26.3 0.0 7.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EMC98230.1 - 0.00014 21.4 0.1 0.00032 20.2 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EMC98230.1 - 0.0071 15.6 0.0 0.087 12.1 0.0 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EMC98230.1 - 0.0074 16.0 0.0 0.037 13.7 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EMC98230.1 - 0.045 13.4 0.0 4 7.0 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC98230.1 - 0.069 13.8 0.2 0.11 13.1 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAE PF03283.13 EMC98230.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase Usp PF00582.26 EMC98231.1 - 1.4e-18 67.8 1.2 3.8e-14 53.4 0.1 3.0 3 0 0 3 3 3 2 Universal stress protein family p450 PF00067.22 EMC98232.1 - 5.1e-37 127.7 0.0 6.8e-36 124.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EMC98233.1 - 7e-06 25.8 0.2 2.7e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EMC98233.1 - 0.00019 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EMC98233.1 - 0.021 14.7 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box Zn_clus PF00172.18 EMC98235.1 - 7e-08 32.5 7.3 1.1e-07 31.8 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.6 EMC98236.1 - 1.9e-14 53.7 0.8 4.2e-14 52.6 0.8 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family 7tm_1 PF00001.21 EMC98236.1 - 0.029 13.7 4.0 0.046 13.1 4.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Zn_clus PF00172.18 EMC98237.1 - 0.005 16.9 7.9 0.012 15.7 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyltransferase PF01553.21 EMC98239.1 - 4.6e-12 45.7 0.0 2.7e-05 23.8 0.0 2.7 3 0 0 3 3 3 2 Acyltransferase Glyco_hydro_47 PF01532.20 EMC98240.1 - 2.3e-122 409.2 0.9 2.9e-122 408.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ATP-synt_C PF00137.21 EMC98242.1 - 4e-10 39.9 14.3 7.2e-10 39.1 14.3 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Enamelin PF15362.6 EMC98242.1 - 0.079 11.3 0.1 0.09 11.1 0.1 1.0 1 0 0 1 1 1 0 Enamelin 2OG-FeII_Oxy PF03171.20 EMC98243.1 - 8.1e-20 71.2 0.0 1.7e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EMC98243.1 - 2.1e-12 47.8 0.0 3.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal SAPS PF04499.15 EMC98244.1 - 5.6e-179 596.0 2.8 8.9e-179 595.3 0.1 2.4 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein XPC-binding PF09280.11 EMC98244.1 - 0.15 11.8 0.1 17 5.2 0.3 2.7 2 0 0 2 2 2 0 XPC-binding domain Vps36_ESCRT-II PF11605.8 EMC98245.1 - 0.021 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 EMC98245.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 GRAM domain ADH_zinc_N_2 PF13602.6 EMC98246.1 - 2.6e-20 73.8 0.0 8e-20 72.3 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMC98246.1 - 8.2e-16 58.2 0.1 1.4e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC98246.1 - 2.9e-09 36.8 0.0 3.7e-07 30.0 0.0 2.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EMC98246.1 - 0.00078 19.0 0.5 0.0012 18.3 0.5 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 EMC98246.1 - 0.031 14.2 0.0 0.097 12.6 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase PALP PF00291.25 EMC98246.1 - 0.032 13.6 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 EMC98246.1 - 0.094 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain LpxD PF04613.14 EMC98246.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD NAD_binding_10 PF13460.6 EMC98246.1 - 0.13 12.2 1.5 0.2 11.5 1.5 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Fungal_trans_2 PF11951.8 EMC98247.1 - 5.1e-11 42.0 4.1 4.6e-10 38.9 0.6 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC98247.1 - 6.3e-07 29.4 10.8 1.2e-06 28.5 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_N PF00108.23 EMC98250.1 - 1.6e-72 244.0 2.0 1.6e-72 244.0 2.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMC98250.1 - 1.2e-44 150.9 0.1 2.5e-44 149.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EMC98250.1 - 0.0091 15.6 2.3 0.093 12.3 0.8 2.9 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 EMC98250.1 - 0.038 14.2 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3520 PF12034.8 EMC98250.1 - 0.042 14.0 0.2 0.37 10.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3520) ACP_syn_III PF08545.10 EMC98250.1 - 0.05 13.5 0.6 16 5.4 0.1 2.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CutC PF03932.14 EMC98251.1 - 6.3e-61 205.4 0.0 7.5e-61 205.1 0.0 1.0 1 0 0 1 1 1 1 CutC family TP_methylase PF00590.20 EMC98252.1 - 5.4e-49 167.0 0.5 9.5e-49 166.2 0.0 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EMC98252.1 - 1.4e-12 48.0 0.0 2.7e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EMC98252.1 - 6.8e-11 41.6 0.1 8e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EMC98252.1 - 7.3e-10 38.1 0.1 2.2e-09 36.6 0.1 1.9 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Rogdi_lz PF10259.9 EMC98253.1 - 2.6e-88 296.0 0.0 2.9e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.12 EMC98254.1 - 4.4e-28 98.4 9.3 5.3e-28 98.1 9.3 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 EMC98254.1 - 0.12 12.2 10.6 0.24 11.2 10.6 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF3435 PF11917.8 EMC98256.1 - 3.2e-10 39.5 0.1 2.6e-08 33.2 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF3435) zf-Di19 PF05605.12 EMC98256.1 - 0.0029 17.9 0.2 0.0082 16.4 0.2 1.8 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding MFS_1 PF07690.16 EMC98259.1 - 1.6e-43 149.0 29.8 1.6e-43 149.0 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98259.1 - 5.5e-16 58.5 5.5 5.5e-16 58.5 5.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMC98259.1 - 5.1e-05 21.9 2.4 8e-05 21.2 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mntp PF02659.15 EMC98259.1 - 0.0067 16.2 0.1 0.0067 16.2 0.1 3.0 4 0 0 4 4 4 1 Putative manganese efflux pump MFS_3 PF05977.13 EMC98259.1 - 0.0073 14.8 1.1 0.011 14.2 1.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector DUF4179 PF13786.6 EMC98259.1 - 0.031 14.7 1.6 14 6.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Vps51 PF08700.11 EMC98260.1 - 0.027 14.6 0.8 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 Vps51/Vps67 Peptidase_S9 PF00326.21 EMC98260.1 - 0.18 11.3 2.4 0.27 10.7 2.4 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family FXR_C1 PF16096.5 EMC98260.1 - 2.1 8.6 8.3 5.4 7.3 0.1 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 NOA36 PF06524.12 EMC98261.1 - 0.0041 16.5 3.0 0.0041 16.5 3.0 1.9 2 0 0 2 2 2 1 NOA36 protein RXT2_N PF08595.11 EMC98261.1 - 0.33 10.9 6.6 0.16 12.0 3.0 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Rick_17kDa_Anti PF05433.15 EMC98262.1 - 0.00018 21.3 13.5 0.00018 21.3 13.5 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain Hemagglutinin PF00509.18 EMC98262.1 - 1.4 7.3 2.4 1.9 6.8 2.4 1.1 1 0 0 1 1 1 0 Haemagglutinin Gly-zipper_YMGG PF13441.6 EMC98262.1 - 5.2 6.9 19.9 0.64 9.8 15.3 1.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper RCC1_2 PF13540.6 EMC98263.1 - 1.2e-09 37.7 15.3 0.0023 17.7 0.3 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EMC98263.1 - 4.4e-06 26.5 1.9 4.9e-06 26.3 0.7 1.7 2 0 0 2 2 2 1 F-box-like RCC1 PF00415.18 EMC98263.1 - 0.00015 22.3 9.4 0.0023 18.5 0.1 4.8 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 EMC98263.1 - 0.001 18.9 0.2 0.0022 17.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EMC98263.1 - 0.13 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 F-box Acetyltransf_10 PF13673.7 EMC98264.1 - 6.4e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC98264.1 - 3.2e-07 30.7 0.0 6.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC98264.1 - 4.3e-07 30.2 0.0 7.4e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMC98264.1 - 0.00082 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMC98264.1 - 0.0013 18.8 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EMC98264.1 - 0.0023 18.0 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF5442 PF17514.2 EMC98264.1 - 0.18 12.0 0.2 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Utp8 PF10395.9 EMC98265.1 - 1.3e-05 24.0 0.0 2.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Utp8 family DUF2530 PF10745.9 EMC98265.1 - 0.076 13.3 1.4 0.21 11.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) EF-hand_8 PF13833.6 EMC98266.1 - 0.012 15.4 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 EMC98266.1 - 0.013 16.0 0.0 0.44 11.0 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain pair Skp1 PF01466.19 EMC98266.1 - 0.57 10.3 3.1 1.1 9.5 0.4 2.3 2 0 0 2 2 2 0 Skp1 family, dimerisation domain DOT1 PF08123.13 EMC98267.1 - 5.7e-69 231.7 0.0 7.9e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 EMC98267.1 - 0.0019 18.0 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC98267.1 - 0.012 16.2 0.0 0.029 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Nucleo_P87 PF07267.11 EMC98267.1 - 0.18 10.6 2.7 0.26 10.1 2.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1264 PF06884.11 EMC98268.1 - 1.4e-78 262.4 0.1 1.6e-78 262.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF4449 PF14613.6 EMC98269.1 - 4.7e-68 228.4 6.7 4.7e-68 228.4 6.7 3.0 3 1 0 4 4 4 1 Protein of unknown function (DUF4449) Prp18 PF02840.15 EMC98269.1 - 0.018 15.1 0.2 0.018 15.1 0.2 3.7 2 2 1 4 4 4 0 Prp18 domain DUF496 PF04363.12 EMC98269.1 - 1.1 9.3 6.4 0.59 10.2 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF496) HEPN_Swt1 PF18731.1 EMC98269.1 - 7.8 6.9 8.3 0.5 10.7 0.9 2.7 2 1 0 2 2 2 0 Swt1-like HEPN DNMT1-RFD PF12047.8 EMC98270.1 - 0.023 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain AT_hook PF02178.19 EMC98270.1 - 0.92 9.6 7.2 3.3 7.9 7.2 2.0 1 0 0 1 1 1 0 AT hook motif TruB_N PF01509.18 EMC98271.1 - 1.8e-47 161.5 0.0 1.3e-46 158.7 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EMC98271.1 - 9.5e-07 28.9 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Cyclase PF04199.13 EMC98272.1 - 2.5e-31 108.7 0.0 3.4e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF3176 PF11374.8 EMC98273.1 - 0.015 15.5 0.1 0.069 13.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) HSP20 PF00011.21 EMC98274.1 - 2.9e-10 40.2 0.0 4.2e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF4211 PF13926.6 EMC98275.1 - 2.2e-41 141.3 0.0 2.2e-41 141.3 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4211) Zn_clus PF00172.18 EMC98275.1 - 0.027 14.6 0.7 0.054 13.6 0.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-B_dimeris PF09026.10 EMC98275.1 - 0.61 10.5 9.4 1.1 9.6 5.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DcpS_C PF11969.8 EMC98276.1 - 5.7e-16 59.0 2.6 1.5e-14 54.5 2.6 2.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EMC98276.1 - 1.1e-14 54.9 0.0 2.5e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 EMC98276.1 - 3.2e-12 46.7 0.2 7.3e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger EF-hand_like PF09279.11 EMC98277.1 - 0.096 13.2 0.2 0.2 12.2 0.2 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF1041 PF06292.17 EMC98277.1 - 0.1 13.0 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) zf_CCCH_4 PF18345.1 EMC98277.1 - 0.2 11.8 12.0 0.82 9.8 0.4 3.7 3 0 0 3 3 3 0 Zinc finger domain Amidase PF01425.21 EMC98278.1 - 8e-56 189.9 0.3 2e-53 182.0 0.1 2.1 2 0 0 2 2 2 2 Amidase Arm PF00514.23 EMC98279.1 - 1.6e-76 250.2 27.1 1e-12 47.6 0.1 11.2 11 1 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EMC98279.1 - 7.7e-20 71.1 8.7 9.3e-05 22.7 0.1 7.1 3 3 2 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 EMC98279.1 - 8.8e-18 64.4 15.0 0.0023 18.4 0.0 8.4 6 2 3 9 9 9 4 HEAT-like repeat HEAT PF02985.22 EMC98279.1 - 1.1e-16 59.4 11.2 0.1 12.9 0.0 9.2 9 0 0 9 9 9 5 HEAT repeat Arm_2 PF04826.13 EMC98279.1 - 1.1e-12 48.0 1.9 2.9e-07 30.2 0.2 2.6 1 1 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 EMC98279.1 - 1.9e-12 46.6 2.5 4.3e-07 28.9 0.1 2.8 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 EMC98279.1 - 2.4e-09 35.9 0.1 7.1e-09 34.4 0.1 1.7 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EMC98279.1 - 3.9e-07 29.7 0.1 0.0012 18.3 0.0 3.1 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 EMC98279.1 - 1.6e-06 28.3 2.1 0.0083 16.2 0.2 4.9 1 1 3 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EMC98279.1 - 0.00022 21.2 4.1 5.4 6.9 0.1 4.3 2 1 4 6 6 6 2 Domain of unknown function (DUF3361) DUF5578 PF17741.1 EMC98279.1 - 0.00067 19.2 4.3 4.8 6.5 0.0 4.7 2 1 4 6 6 6 1 Family of unknown function (DUF5578) IFRD PF05004.13 EMC98279.1 - 0.0033 16.6 0.7 1.2 8.1 0.1 3.4 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Atx10homo_assoc PF09759.9 EMC98279.1 - 0.0061 16.6 2.2 2.5 8.2 0.1 4.7 3 1 3 6 6 6 1 Spinocerebellar ataxia type 10 protein domain RTP1_C1 PF10363.9 EMC98279.1 - 0.051 13.8 1.3 37 4.5 0.0 4.2 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EMC98279.1 - 0.12 13.0 0.0 1.7 9.3 0.0 2.9 3 1 1 4 4 2 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 EMC98279.1 - 0.15 12.8 7.9 55 4.9 0.1 6.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat WAPL PF07814.13 EMC98279.1 - 0.42 9.4 4.1 6.5 5.4 4.1 2.4 1 1 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin RasGEF_N_2 PF14663.6 EMC98279.1 - 3.4 8.1 4.6 59 4.1 0.1 3.9 2 1 3 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pkinase PF00069.25 EMC98280.1 - 6.1e-45 153.6 0.0 7.5e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC98280.1 - 1.9e-29 102.7 0.0 5.7e-28 97.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Sororin PF09666.10 EMC98280.1 - 0.025 14.8 1.5 0.054 13.7 1.5 1.5 1 0 0 1 1 1 0 Sororin protein Kinase-like PF14531.6 EMC98280.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EMC98280.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Mif2_N PF15624.6 EMC98280.1 - 0.81 10.4 3.4 2 9.2 3.4 1.7 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal EamA PF00892.20 EMC98282.1 - 2.6e-15 56.8 33.7 6.3e-09 36.1 3.5 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 EMC98282.1 - 8.4e-07 28.8 0.9 8.4e-07 28.8 0.9 2.8 2 1 1 3 3 3 2 Solute carrier family 35 PUNUT PF16913.5 EMC98282.1 - 9e-05 21.8 12.3 9e-05 21.8 12.3 2.3 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 EMC98282.1 - 9.3e-05 22.2 0.7 9.3e-05 22.2 0.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) CRT-like PF08627.10 EMC98282.1 - 0.0014 17.6 2.3 0.27 10.1 1.0 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Methyltransf_23 PF13489.6 EMC98284.1 - 3.1e-16 59.7 0.0 4.4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC98284.1 - 8.3e-12 45.6 0.0 1.3e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC98284.1 - 6.2e-11 42.9 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC98284.1 - 2.4e-08 34.6 0.0 4.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC98284.1 - 2.9e-08 33.7 0.0 3.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC98284.1 - 3.5e-06 26.5 0.0 4.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EMC98284.1 - 0.055 14.5 0.0 0.18 12.8 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 EMC98284.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.19 EMC98284.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) JHBP PF06585.11 EMC98285.1 - 0.0068 15.6 0.0 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) Porin_3 PF01459.22 EMC98288.1 - 1e-75 254.7 0.0 1.2e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.18 EMC98289.1 - 1.7e-64 217.2 0.1 2.4e-64 216.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EMC98289.1 - 4.4e-20 72.2 0.1 5.3e-19 68.7 0.1 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EMC98289.1 - 0.0027 17.9 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMC98289.1 - 0.0089 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 EMC98289.1 - 0.026 14.4 0.0 0.45 10.4 0.0 2.2 1 1 0 1 1 1 0 Adenylylsulphate kinase DUF3445 PF11927.8 EMC98289.1 - 0.083 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) DUF4112 PF13430.6 EMC98290.1 - 2e-32 111.6 0.7 2.5e-32 111.2 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Lung_7-TM_R PF06814.13 EMC98291.1 - 3.2e-68 230.2 16.2 3.8e-68 229.9 16.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GATA PF00320.27 EMC98293.1 - 0.00063 19.3 3.8 0.17 11.5 1.0 2.6 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.22 EMC98294.1 - 1.6e-18 66.1 0.1 2.3e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain Dak1 PF02733.17 EMC98295.1 - 1.6e-106 355.7 7.7 2.9e-106 354.9 7.7 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EMC98295.1 - 4e-47 160.3 4.5 1.3e-46 158.7 4.5 1.9 1 0 0 1 1 1 1 DAK2 domain DLEU7 PF15760.5 EMC98295.1 - 0.0023 17.4 0.1 0.0049 16.4 0.1 1.5 1 0 0 1 1 1 1 Leukemia-associated protein 7 DUF1442 PF07279.11 EMC98295.1 - 0.28 10.5 2.8 0.74 9.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) PEX11 PF05648.14 EMC98297.1 - 1.9e-08 34.0 0.6 6.5e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) TFA2_Winged_2 PF18121.1 EMC98298.1 - 8.4e-22 76.6 0.0 2e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EMC98298.1 - 1.6e-18 66.7 1.0 4.9e-18 65.2 0.2 2.2 2 0 0 2 2 2 1 TFIIE beta subunit core domain Pyr_redox_2 PF07992.14 EMC98299.1 - 3.5e-15 56.0 0.0 4.6e-12 45.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EMC98299.1 - 1.7e-13 49.9 0.0 1.8e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMC98299.1 - 3.3e-13 49.5 0.1 1.7e-12 47.2 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC98299.1 - 7.8e-10 38.4 0.0 1.7e-06 27.4 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EMC98299.1 - 1.3e-06 28.9 0.9 0.037 14.6 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC98299.1 - 1e-05 25.6 0.1 3.9e-05 23.8 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EMC98299.1 - 3.3e-05 23.3 1.4 4.5e-05 22.9 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EMC98299.1 - 0.00047 19.8 2.1 0.0019 17.8 2.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMC98299.1 - 0.00051 19.3 0.1 0.0011 18.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EMC98299.1 - 0.0016 18.4 0.2 1.6 8.7 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EMC98299.1 - 0.0022 17.1 0.0 0.016 14.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 EMC98299.1 - 0.0028 16.4 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EMC98299.1 - 0.003 16.8 0.0 0.0079 15.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 EMC98299.1 - 0.006 16.0 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1582 PF07621.11 EMC98299.1 - 0.072 13.0 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) TrkA_N PF02254.18 EMC98299.1 - 0.098 12.9 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Amino_oxidase PF01593.24 EMC98299.1 - 0.099 11.9 1.3 0.58 9.4 0.1 2.8 4 1 1 5 5 5 0 Flavin containing amine oxidoreductase XdhC_C PF13478.6 EMC98299.1 - 0.16 12.5 0.0 5.8 7.4 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Cu-oxidase_2 PF07731.14 EMC98300.1 - 1.5e-40 138.1 6.9 1.4e-39 134.9 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EMC98300.1 - 3.6e-40 136.7 8.9 5.6e-39 132.8 1.1 3.8 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EMC98300.1 - 1.4e-31 109.7 0.8 1.4e-31 109.7 0.8 2.0 3 0 0 3 3 3 1 Multicopper oxidase fn3 PF00041.21 EMC98300.1 - 0.2 12.0 2.1 27 5.2 0.1 3.4 3 0 0 3 3 3 0 Fibronectin type III domain OCD_Mu_crystall PF02423.15 EMC98302.1 - 5.5e-12 45.2 1.4 0.0009 18.3 0.2 3.4 3 1 1 4 4 4 3 Ornithine cyclodeaminase/mu-crystallin family MCU PF04678.13 EMC98303.1 - 1.1e-25 90.7 0.9 1.1e-25 90.7 0.9 1.9 3 0 0 3 3 3 1 Mitochondrial calcium uniporter Mito_carr PF00153.27 EMC98304.1 - 3.3e-60 200.0 2.3 3.2e-21 75.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Esterase_phd PF10503.9 EMC98305.1 - 3.2e-06 26.8 0.6 4.1e-06 26.5 0.6 1.3 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMC98305.1 - 3.1e-05 23.6 0.7 0.00013 21.5 0.4 2.1 1 1 2 3 3 3 1 Prolyl oligopeptidase family Esterase PF00756.20 EMC98305.1 - 0.00012 21.9 0.2 0.00014 21.6 0.2 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EMC98305.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 EMC98305.1 - 0.017 13.8 0.2 0.68 8.6 0.0 2.3 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Ribosomal_L7Ae PF01248.26 EMC98306.1 - 8.8e-21 73.5 0.8 1.3e-20 72.9 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RepB PF07506.11 EMC98306.1 - 0.027 14.5 1.1 3.4 7.7 0.0 2.2 2 0 0 2 2 2 0 RepB plasmid partitioning protein RGS_DHEX PF18148.1 EMC98306.1 - 0.058 13.5 0.6 0.15 12.2 0.6 1.7 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain Sld5 PF05916.11 EMC98308.1 - 8e-18 64.9 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein BLM10_mid PF16507.5 EMC98309.1 - 3.1e-200 666.3 0.0 1e-199 664.6 0.0 1.8 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EMC98309.1 - 1.6e-30 104.8 0.0 1.4e-29 101.8 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EMC98309.1 - 3.1e-19 69.0 0.0 7.5e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 EMC98309.1 - 0.00016 21.6 0.4 0.64 10.4 0.1 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EMC98309.1 - 0.00026 21.3 0.9 8.3 6.9 0.0 5.1 6 0 0 6 6 6 2 HEAT repeats CLASP_N PF12348.8 EMC98309.1 - 0.0011 18.6 0.1 0.14 11.7 0.0 2.9 2 0 0 2 2 2 1 CLASP N terminal Atg14 PF10186.9 EMC98309.1 - 0.0026 16.9 0.1 0.0046 16.1 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 HEAT_EZ PF13513.6 EMC98309.1 - 0.12 12.9 1.0 35 5.0 0.1 4.3 4 0 0 4 4 4 0 HEAT-like repeat ATPase PF06745.13 EMC98309.1 - 0.18 11.1 0.2 0.36 10.2 0.2 1.4 1 0 0 1 1 1 0 KaiC Lipase_3 PF01764.25 EMC98310.1 - 9.8e-16 57.9 0.0 1.5e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EMC98310.1 - 0.0076 15.8 0.0 3.8 7.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EMC98310.1 - 0.016 15.9 0.0 0.041 14.5 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family peroxidase PF00141.23 EMC98311.1 - 4.7e-46 157.3 0.0 6.4e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ZirS_C PF16583.5 EMC98313.1 - 0.22 11.1 1.4 0.45 10.1 1.4 1.4 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain NTP_transferase PF00483.23 EMC98314.1 - 2.8e-53 181.0 0.0 5.3e-53 180.1 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EMC98314.1 - 3e-15 55.3 7.1 1.9e-11 43.2 1.4 3.9 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EMC98314.1 - 1.8e-10 41.4 0.0 2.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EMC98314.1 - 2e-06 27.4 0.5 2e-06 27.4 0.5 3.3 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EMC98314.1 - 4.9e-05 21.7 0.3 0.00026 19.3 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) IspD PF01128.19 EMC98314.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DND1_DSRM PF14709.7 EMC98315.1 - 0.0019 18.4 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 EMC98315.1 - 0.0027 18.4 0.1 0.008 16.9 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif BRAP2 PF07576.12 EMC98316.1 - 3.1e-31 107.5 0.0 5.6e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EMC98316.1 - 2.5e-20 72.6 8.6 6.7e-20 71.2 8.6 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EMC98316.1 - 2.9e-08 33.9 8.8 2.9e-08 33.9 8.8 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMC98316.1 - 2.4e-06 27.3 8.2 6.4e-06 25.9 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC98316.1 - 6.3e-05 22.8 7.3 6.3e-05 22.8 7.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMC98316.1 - 0.00017 21.8 6.0 0.00054 20.2 6.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EMC98316.1 - 0.00038 20.1 4.9 0.00038 20.1 4.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EMC98316.1 - 0.00062 19.7 4.8 0.00062 19.7 4.8 2.3 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EMC98316.1 - 0.0018 18.1 6.8 0.0018 18.1 6.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC98316.1 - 0.0027 17.6 6.5 0.0027 17.6 6.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EMC98316.1 - 0.0093 15.8 3.3 0.0093 15.8 3.3 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EMC98316.1 - 0.028 14.5 5.6 0.082 13.0 5.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ATG16 PF08614.11 EMC98316.1 - 0.077 13.2 18.4 0.17 12.1 18.4 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1993 PF09351.10 EMC98316.1 - 0.58 10.3 10.5 0.13 12.4 4.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Prok-RING_4 PF14447.6 EMC98316.1 - 0.71 9.8 19.1 0.33 10.9 9.4 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EMC98316.1 - 2 8.1 13.4 0.069 12.8 5.0 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Exonuc_VII_L PF02601.15 EMC98316.1 - 5.2 6.5 11.4 8.2 5.9 11.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 EMC98316.1 - 9.5 6.4 7.0 11 6.3 3.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ubiquitin PF00240.23 EMC98317.1 - 5.4e-102 333.6 13.3 1.9e-33 114.0 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EMC98317.1 - 1.3e-48 162.7 13.8 1.2e-15 57.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EMC98317.1 - 7.5e-18 64.8 6.1 0.00026 21.4 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EMC98317.1 - 1.6e-12 47.6 2.3 0.014 15.7 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EMC98317.1 - 1.7e-12 47.1 1.7 0.016 15.1 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMC98317.1 - 4.7e-11 42.8 1.3 0.073 13.2 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMC98317.1 - 7.2e-10 39.4 0.3 0.21 12.1 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EMC98317.1 - 1.7e-08 34.4 0.3 0.3 10.9 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EMC98317.1 - 2.4e-06 27.5 16.0 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 EMC98317.1 - 8.5e-05 22.7 1.0 8 6.7 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 EMC98317.1 - 0.00015 21.5 2.1 6.9 6.6 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF2870 PF11069.8 EMC98317.1 - 0.00027 21.2 0.0 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 EMC98317.1 - 0.00058 19.3 0.1 1.1 8.5 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 EMC98317.1 - 0.0011 19.6 0.1 34 5.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain YcgR_2 PF12945.7 EMC98317.1 - 0.003 17.7 2.9 19 5.5 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR UDP-g_GGTase PF06427.11 EMC98317.1 - 0.0069 16.5 3.0 4.5 7.4 0.0 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EMC98317.1 - 0.0076 15.7 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) DUF493 PF04359.14 EMC98317.1 - 0.031 14.9 0.0 95 3.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 EMC98317.1 - 0.031 14.0 0.0 71 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 EMC98317.1 - 0.032 14.8 0.3 96 3.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain ORF11CD3 PF10549.9 EMC98317.1 - 0.088 12.9 0.0 62 3.8 0.0 3.4 3 0 0 3 3 3 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EMC98317.1 - 0.12 12.5 2.6 72 3.6 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 EMC98317.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif Myosin_N PF02736.19 EMC98317.1 - 0.27 11.1 3.4 76 3.3 0.0 4.3 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 EMC98317.1 - 0.44 10.2 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Plexin_cytopl PF08337.12 EMC98317.1 - 0.53 8.9 10.5 8.3 4.9 0.4 3.9 2 1 1 4 4 4 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 EMC98317.1 - 0.85 9.4 5.0 67 3.3 0.1 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain FlgD_ig PF13860.6 EMC98317.1 - 2.8 7.9 4.9 1.2e+02 2.6 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Methyltransf_23 PF13489.6 EMC98318.1 - 5.5e-18 65.3 0.0 9.1e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC98318.1 - 1.2e-10 42.0 0.0 9.4e-10 39.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC98318.1 - 2.2e-08 34.6 0.0 1.5e-07 31.9 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC98318.1 - 1.7e-07 31.9 0.0 1.9e-06 28.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC98318.1 - 1.7e-07 31.1 0.0 4.9e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EMC98318.1 - 0.0003 20.9 0.0 0.00088 19.4 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EMC98318.1 - 0.00051 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EMC98318.1 - 0.051 13.1 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EMC98318.1 - 0.064 12.6 0.0 0.22 10.8 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.22 EMC98319.1 - 2e-41 142.2 0.0 2.8e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.22 EMC98320.1 - 1.9e-75 254.9 0.3 1.3e-74 252.1 0.3 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase E1_dh PF00676.20 EMC98322.1 - 1.7e-62 211.1 0.0 2.4e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 EMC98322.1 - 2e-62 210.0 0.0 3.3e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EMC98322.1 - 1.7e-54 183.6 0.0 2.8e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EMC98322.1 - 2.2e-20 72.0 1.8 4.7e-20 70.9 1.8 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Glyco_hydro81C PF17652.1 EMC98323.1 - 5.1e-154 512.7 3.7 6.5e-154 512.4 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EMC98323.1 - 8.1e-114 380.1 4.6 2e-113 378.8 1.9 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain GCFC PF07842.12 EMC98326.1 - 1.1e-72 244.9 3.5 1.1e-72 244.9 3.5 1.9 3 0 0 3 3 3 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EMC98326.1 - 1.7e-16 59.8 3.7 3.9e-16 58.7 3.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EMC98326.1 - 4e-07 30.0 1.0 4e-07 30.0 1.0 2.2 2 0 0 2 2 2 1 G-patch domain RapA_C PF12137.8 EMC98326.1 - 0.012 14.6 1.5 0.02 13.9 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Inositol_P PF00459.25 EMC98329.1 - 8.1e-11 41.9 0.0 9e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RNA_pol_Rpb6 PF01192.22 EMC98329.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb6 Shikimate_dh_N PF08501.11 EMC98330.1 - 2.5e-22 78.9 0.0 4.9e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EMC98330.1 - 0.00023 20.9 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Sugar_tr PF00083.24 EMC98331.1 - 2.3e-130 435.5 26.2 2.6e-130 435.3 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC98331.1 - 9.4e-20 70.8 42.8 9.4e-20 70.8 42.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 EMC98332.1 - 4.5e-26 92.0 0.1 6.6e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EMC98332.1 - 3.1e-12 46.5 0.0 5.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 EMC98332.1 - 0.019 15.6 0.0 0.039 14.6 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain AP_endonuc_2 PF01261.24 EMC98333.1 - 3e-33 115.1 0.0 4.1e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel NAD_binding_11 PF14833.6 EMC98333.1 - 0.11 12.7 0.0 0.36 11.1 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.22 EMC98334.1 - 4.6e-79 260.2 4.0 3e-21 75.0 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EMC98334.1 - 2.3e-28 98.2 1.3 4.7e-28 97.2 0.3 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EMC98334.1 - 1.1e-11 44.3 0.2 0.0027 17.3 0.0 5.1 2 1 3 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC98334.1 - 3.7e-06 26.7 0.1 0.091 12.6 0.0 4.0 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EMC98334.1 - 0.00048 20.1 0.8 9.6 6.3 0.1 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 EMC98334.1 - 0.0022 18.5 12.5 0.014 15.9 1.5 3.7 4 0 0 4 4 4 2 Heat induced stress protein YflT RRM_7 PF16367.5 EMC98334.1 - 0.0038 17.3 0.2 37 4.5 0.0 5.1 5 1 0 5 5 5 0 RNA recognition motif RRM_3 PF08777.11 EMC98334.1 - 0.0044 17.0 10.4 1.2 9.2 3.6 4.8 3 1 2 5 5 5 1 RNA binding motif Limkain-b1 PF11608.8 EMC98334.1 - 0.0046 17.0 0.3 4.5 7.4 0.0 3.4 3 0 0 3 3 3 1 Limkain b1 OB_RNB PF08206.11 EMC98334.1 - 0.016 14.9 0.6 16 5.2 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain CbiG_mid PF11761.8 EMC98334.1 - 0.016 15.3 0.0 27 4.9 0.0 3.4 3 0 0 3 3 3 0 Cobalamin biosynthesis central region IF2_N PF04760.15 EMC98334.1 - 0.042 13.7 0.2 8.4 6.3 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region RTX PF02382.15 EMC98335.1 - 0.024 14.3 0.9 0.029 14.1 0.9 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Chlorosome_CsmC PF11098.8 EMC98335.1 - 0.41 10.6 11.1 0.97 9.4 11.1 1.6 1 1 0 1 1 1 0 Chlorosome envelope protein C EF-hand_7 PF13499.6 EMC98336.1 - 2.8e-18 66.1 1.2 3.8e-11 43.3 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EMC98336.1 - 1.6e-17 61.7 4.3 7.8e-08 31.3 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EMC98336.1 - 3.7e-15 54.5 4.3 1.9e-07 30.5 0.2 3.6 4 1 1 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 EMC98336.1 - 3e-13 49.4 1.6 7.9e-07 28.8 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EMC98336.1 - 8.8e-08 31.3 4.4 0.00066 19.1 0.1 3.3 3 1 1 4 4 4 2 EF hand EF-hand_9 PF14658.6 EMC98336.1 - 1.6e-05 25.1 0.0 0.00047 20.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EMC98336.1 - 0.00087 19.2 0.1 0.045 13.7 0.0 2.3 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Methyltransf_3 PF01596.17 EMC98336.1 - 0.022 13.9 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase TerB PF05099.13 EMC98336.1 - 0.048 13.6 4.1 0.13 12.3 0.4 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 EMC98336.1 - 0.2 12.0 0.2 0.7 10.2 0.1 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4834 PF16118.5 EMC98336.1 - 0.21 12.5 2.5 0.42 11.6 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM213 PF15192.6 EMC98338.1 - 0.082 12.9 0.7 0.11 12.5 0.7 1.2 1 1 0 1 1 1 0 TMEM213 family MATalpha_HMGbox PF04769.12 EMC98339.1 - 0.00033 20.0 0.0 0.00037 19.9 0.0 1.0 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Pro_CA PF00484.19 EMC98341.1 - 4.9e-43 147.1 0.0 6.7e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Velvet PF11754.8 EMC98343.1 - 2.3e-30 106.4 4.5 4.1e-26 92.4 0.1 3.1 2 1 1 3 3 3 2 Velvet factor Uds1 PF15456.6 EMC98344.1 - 2.8e-37 127.8 1.2 2.8e-37 127.8 1.2 8.5 2 2 3 5 5 5 1 Up-regulated During Septation GAS PF13851.6 EMC98344.1 - 0.0032 16.9 5.3 0.0032 16.9 5.3 8.5 6 2 3 9 9 9 3 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 EMC98344.1 - 0.0052 16.1 1.3 0.0052 16.1 1.3 8.4 5 2 5 10 10 10 3 Protein of unknown function (DUF3450) SlyX PF04102.12 EMC98344.1 - 0.023 15.3 0.7 0.023 15.3 0.7 11.3 8 3 5 13 13 13 0 SlyX MerR-DNA-bind PF09278.11 EMC98344.1 - 0.091 13.3 0.3 0.091 13.3 0.3 10.6 11 5 1 13 13 13 0 MerR, DNA binding ORF11CD3 PF10549.9 EMC98344.1 - 0.25 11.5 6.9 5.9 7.1 0.1 4.1 4 0 0 4 4 4 0 ORF11CD3 domain Aminotran_1_2 PF00155.21 EMC98345.1 - 0.058 12.6 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II TPR_22 PF18833.1 EMC98345.1 - 0.086 13.0 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 EMC98346.1 - 8.8e-08 31.7 0.0 9.2e-08 31.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MWFE PF15879.5 EMC98348.1 - 5.3e-32 109.8 0.2 6.5e-32 109.5 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 EMC98349.1 - 8.5e-66 221.0 0.0 2.8e-32 111.8 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 EMC98349.1 - 1.2e-19 69.6 5.3 2.9e-19 68.4 5.3 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 EMC98349.1 - 1.7e-09 37.6 2.5 1.7e-09 37.6 2.5 2.0 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EMC98349.1 - 0.0011 18.8 4.5 0.0011 18.8 4.5 2.3 2 0 0 2 2 2 1 PHD-finger ANT PF03374.14 EMC98349.1 - 0.042 14.2 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain V_ATPase_I PF01496.19 EMC98350.1 - 0 1077.5 0.0 0 1077.3 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 EMC98350.1 - 0.00094 19.2 2.0 0.0033 17.4 0.4 2.1 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ Filament PF00038.21 EMC98350.1 - 0.0071 16.0 4.3 0.16 11.5 0.5 2.3 2 0 0 2 2 2 1 Intermediate filament protein Serine_rich PF08824.10 EMC98350.1 - 0.017 15.1 0.7 0.047 13.7 0.1 1.9 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF16 PF01519.16 EMC98350.1 - 0.022 15.3 1.7 0.52 10.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 DivIC PF04977.15 EMC98350.1 - 0.11 12.3 0.2 0.75 9.6 0.2 2.5 1 0 0 1 1 1 0 Septum formation initiator PI3K_P85_iSH2 PF16454.5 EMC98350.1 - 0.12 12.0 2.2 4.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 EMC98350.1 - 0.12 12.4 3.4 4.5 7.3 0.1 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 EMC98350.1 - 0.21 11.7 1.8 1.6 8.8 0.2 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4988 PF16378.5 EMC98350.1 - 0.32 10.6 1.9 0.28 10.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF3450 PF11932.8 EMC98350.1 - 0.33 10.2 4.5 0.16 11.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TBK1_CCD1 PF18394.1 EMC98350.1 - 0.38 10.3 1.7 4.8 6.7 0.2 2.1 2 0 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 Baculo_PEP_C PF04513.12 EMC98350.1 - 0.41 10.7 2.2 3.5 7.7 0.1 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 EMC98350.1 - 0.44 11.0 3.2 1.7 9.1 0.6 2.5 2 0 0 2 2 2 0 Cell division protein ZapB BLOC1_2 PF10046.9 EMC98350.1 - 0.47 10.8 3.0 0.73 10.2 0.3 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rab5-bind PF09311.11 EMC98350.1 - 0.53 9.6 3.7 0.41 10.0 0.8 1.9 2 0 0 2 2 2 0 Rabaptin-like protein HWE_HK PF07536.14 EMC98350.1 - 1.7 9.4 4.9 1.8 9.4 0.1 2.9 3 0 0 3 3 2 0 HWE histidine kinase HMMR_N PF15905.5 EMC98350.1 - 7 6.0 7.0 18 4.6 0.5 2.3 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Aa_trans PF01490.18 EMC98352.1 - 9.8e-72 241.9 25.9 1.2e-71 241.6 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 EMC98352.1 - 1.6e-06 27.2 25.7 1.6e-06 27.2 25.7 1.5 1 1 1 2 2 2 1 Amino acid permease PRP4 PF08799.11 EMC98353.1 - 8 6.1 6.9 3 7.5 0.7 2.8 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like PBP PF01161.20 EMC98355.1 - 1e-06 29.1 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein YTH PF04146.15 EMC98356.1 - 2.1e-36 125.3 0.0 6.7e-35 120.5 0.0 2.0 1 1 0 1 1 1 1 YT521-B-like domain Nramp PF01566.18 EMC98358.1 - 8.1e-83 278.3 19.6 8.1e-83 278.3 19.6 2.1 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Mannosyl_trans2 PF04188.13 EMC98360.1 - 1.8e-48 166.0 10.5 2.6e-48 165.4 10.5 1.2 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) PHD PF00628.29 EMC98361.1 - 2.1e-07 30.7 8.0 2.4e-07 30.5 8.0 1.1 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EMC98361.1 - 0.035 14.3 5.2 0.05 13.9 5.2 1.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain Peptidase_M41 PF01434.18 EMC98362.1 - 4.2e-59 199.6 1.6 7.5e-59 198.8 1.6 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EMC98362.1 - 6.1e-44 149.7 0.0 1.9e-43 148.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMC98362.1 - 5.1e-09 35.8 0.1 1.5e-08 34.3 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 EMC98362.1 - 2.2e-06 27.7 0.0 7.9e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC98362.1 - 5.6e-06 26.8 1.4 0.00019 21.9 1.5 3.4 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EMC98362.1 - 5e-05 22.7 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EMC98362.1 - 0.00012 22.3 0.0 0.058 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EMC98362.1 - 0.00023 20.9 0.0 0.00052 19.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EMC98362.1 - 0.0055 16.9 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EMC98362.1 - 0.0087 15.8 0.2 0.025 14.3 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EMC98362.1 - 0.0097 16.0 0.0 0.054 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EMC98362.1 - 0.016 14.8 1.3 0.51 9.9 0.3 2.5 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EMC98362.1 - 0.02 14.3 0.2 0.047 13.1 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EMC98362.1 - 0.025 15.1 0.1 0.21 12.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 EMC98362.1 - 0.075 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain PACT_coil_coil PF10495.9 EMC98362.1 - 0.08 13.5 0.0 23 5.6 0.0 2.9 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein AAA_28 PF13521.6 EMC98362.1 - 0.083 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EMC98362.1 - 0.085 12.2 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EMC98362.1 - 0.092 12.5 0.0 0.82 9.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EMC98362.1 - 0.097 12.2 0.1 0.38 10.2 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EMC98362.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EMC98362.1 - 0.16 11.9 0.3 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EMC98362.1 - 0.19 11.2 0.7 0.44 10.0 0.2 1.8 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 EMC98362.1 - 0.29 11.6 1.3 2.4 8.7 0.3 2.8 2 1 1 3 3 3 0 ABC transporter COesterase PF00135.28 EMC98363.1 - 4.5e-57 194.1 0.0 6.1e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC98363.1 - 4.4e-11 43.1 0.1 3.4e-10 40.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC98363.1 - 0.0078 15.7 0.0 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.8 EMC98363.1 - 0.0088 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EMC98363.1 - 0.019 15.5 0.1 0.049 14.2 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EMC98363.1 - 0.043 12.7 0.0 0.13 11.1 0.0 1.7 1 1 0 1 1 1 0 Steryl acetyl hydrolase zf-C2H2 PF00096.26 EMC98366.1 - 7.4e-20 70.2 25.3 3.2e-05 24.1 1.7 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC98366.1 - 1.7e-17 62.9 27.4 1.5e-06 28.4 1.2 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMC98366.1 - 2.6e-12 46.4 22.7 0.0036 18.0 1.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMC98366.1 - 1.3e-06 28.6 0.6 7 7.1 0.0 5.0 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC98366.1 - 0.0021 18.4 12.3 6.5 7.3 0.0 5.1 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EMC98366.1 - 0.0032 17.2 9.9 0.018 14.8 0.8 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type FOXP-CC PF16159.5 EMC98366.1 - 0.019 15.6 1.4 9.4 6.9 0.2 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain zf_UBZ PF18439.1 EMC98366.1 - 0.023 14.3 2.0 1 9.0 0.2 2.9 3 0 0 3 3 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_aberr PF17017.5 EMC98366.1 - 0.033 14.3 1.2 2.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf_C2H2_13 PF18508.1 EMC98366.1 - 0.31 10.6 1.3 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Zinc finger domain zf-TRAF PF02176.18 EMC98366.1 - 0.34 11.6 9.8 0.53 11.0 0.6 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger XPA_N PF01286.18 EMC98366.1 - 0.8 9.8 6.3 0.75 9.9 0.5 2.9 3 0 0 3 3 3 0 XPA protein N-terminal LIM PF00412.22 EMC98366.1 - 1.3 9.4 5.8 30 5.0 0.0 3.2 2 1 1 3 3 3 0 LIM domain Zn-ribbon_8 PF09723.10 EMC98366.1 - 2.1 8.5 7.9 15 5.8 1.6 3.0 1 1 3 4 4 4 0 Zinc ribbon domain zf-LYAR PF08790.11 EMC98366.1 - 3.1 7.8 5.3 5.5 7.0 0.1 3.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-CRD PF17979.1 EMC98366.1 - 4.3 7.4 7.4 8.2 6.5 1.7 2.2 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions zf-C2HC_2 PF13913.6 EMC98366.1 - 6.7 6.7 7.6 19 5.3 0.3 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type F-box-like_2 PF13013.6 EMC98368.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.7 1 1 0 1 1 1 0 F-box-like domain DUF1556 PF07590.11 EMC98368.1 - 3.2 8.1 8.4 6.4 7.2 1.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1556) DHBP_synthase PF00926.19 EMC98369.1 - 1.8e-81 272.3 0.0 2.1e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase MFS_1 PF07690.16 EMC98370.1 - 2.2e-30 105.8 28.4 2.2e-30 105.8 28.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98370.1 - 8.4e-07 28.2 3.1 8.4e-07 28.2 3.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter RRM_1 PF00076.22 EMC98374.1 - 6.1e-16 58.0 0.1 4.5e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC98374.1 - 0.068 13.3 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif RRM_Rrp7 PF17799.1 EMC98374.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain MFS_1 PF07690.16 EMC98375.1 - 7.2e-19 67.9 36.9 7.2e-19 67.9 36.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98375.1 - 3.5e-08 32.7 7.3 3.5e-08 32.7 7.3 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter SpoVAB PF13782.6 EMC98375.1 - 0.0034 17.7 0.4 0.0034 17.7 0.4 2.3 2 0 0 2 2 2 1 Stage V sporulation protein AB TIP120 PF08623.10 EMC98376.1 - 3.5e-62 209.1 0.4 1.6e-59 200.4 0.0 3.7 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EMC98376.1 - 5e-14 51.2 5.5 0.74 10.2 0.1 11.2 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.6 EMC98376.1 - 1.8e-10 41.1 12.3 0.56 10.6 0.0 8.2 9 1 1 10 10 8 4 HEAT repeats RTP1_C1 PF10363.9 EMC98376.1 - 7.8e-09 35.7 4.8 0.019 15.1 0.0 6.5 7 1 0 7 7 7 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EMC98376.1 - 7.9e-08 32.6 19.7 21 5.8 0.0 12.3 12 4 2 14 14 14 0 HEAT-like repeat DRIM PF07539.12 EMC98376.1 - 2.8e-07 29.2 1.3 0.8 7.9 0.0 4.9 4 2 1 5 5 5 3 Down-regulated in metastasis Cnd1 PF12717.7 EMC98376.1 - 0.00012 22.1 0.7 0.19 11.7 0.0 4.7 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EMC98376.1 - 0.00021 21.0 0.2 6.1 6.3 0.0 4.9 5 0 0 5 5 5 1 CLASP N terminal DUF3385 PF11865.8 EMC98376.1 - 0.00045 20.2 0.3 22 4.9 0.0 5.2 5 2 0 5 5 5 0 Domain of unknown function (DUF3385) MMS19_C PF12460.8 EMC98376.1 - 0.0007 18.8 7.2 0.35 9.9 0.2 5.4 4 2 2 6 6 6 1 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EMC98376.1 - 0.0071 16.9 1.4 4.3 8.0 0.0 5.0 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 EMC98376.1 - 0.011 14.9 0.0 0.66 9.1 0.0 3.6 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain PUL PF08324.11 EMC98376.1 - 0.037 13.3 0.3 0.17 11.1 0.4 2.0 2 0 0 2 2 2 0 PUL domain IFRD PF05004.13 EMC98376.1 - 1.6 7.8 6.2 2.4 7.2 0.3 4.0 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) bZIP_1 PF00170.21 EMC98379.1 - 4.1e-10 39.6 11.6 4.7e-10 39.4 11.6 1.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMC98379.1 - 2e-08 34.2 12.9 2.5e-08 33.9 12.9 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMC98379.1 - 4e-05 24.0 9.4 4.9e-05 23.8 9.4 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor TSC22 PF01166.18 EMC98379.1 - 0.009 16.3 1.2 0.009 16.3 1.2 1.4 2 0 0 2 2 2 1 TSC-22/dip/bun family Phlebovirus_NSM PF07246.11 EMC98379.1 - 0.053 12.9 3.3 0.057 12.8 3.3 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Wbp11 PF09429.10 EMC98379.1 - 0.14 12.6 7.9 0.16 12.4 7.9 1.1 1 0 0 1 1 1 0 WW domain binding protein 11 M PF02370.16 EMC98379.1 - 0.38 11.5 0.8 0.38 11.5 0.8 2.4 3 0 0 3 3 3 0 M protein repeat Sec2p PF06428.11 EMC98380.1 - 6.6e-13 48.4 8.2 6.6e-13 48.4 8.2 2.6 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p BST2 PF16716.5 EMC98380.1 - 0.0022 18.5 23.0 0.43 11.2 1.6 3.9 2 2 2 4 4 3 3 Bone marrow stromal antigen 2 FlxA PF14282.6 EMC98380.1 - 0.0087 16.0 15.6 0.18 11.8 4.3 2.5 2 0 0 2 2 2 2 FlxA-like protein MbeD_MobD PF04899.12 EMC98380.1 - 0.01 15.9 0.8 0.01 15.9 0.8 3.7 2 2 1 3 3 3 0 MbeD/MobD like Adeno_PIX PF03955.14 EMC98380.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Mvb12 PF09452.10 EMC98380.1 - 0.03 14.8 0.7 0.3 11.6 0.0 2.3 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 DivIC PF04977.15 EMC98380.1 - 0.03 14.1 3.1 0.03 14.1 3.1 4.3 3 2 2 5 5 5 0 Septum formation initiator ATG16 PF08614.11 EMC98380.1 - 0.038 14.2 28.0 0.37 11.0 7.3 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EMC98380.1 - 0.049 13.7 8.5 1.3 9.1 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EMC98380.1 - 0.052 14.2 1.8 0.052 14.2 1.8 4.1 3 2 1 4 4 4 0 SlyX Prefoldin_2 PF01920.20 EMC98380.1 - 0.052 13.5 0.8 0.052 13.5 0.8 3.6 3 1 0 3 3 3 0 Prefoldin subunit TcpS PF17456.2 EMC98380.1 - 0.053 13.6 5.9 0.033 14.2 2.3 2.3 1 1 2 3 3 3 0 Toxin-coregulated pilus protein S FliT PF05400.13 EMC98380.1 - 0.074 13.9 2.1 0.074 13.9 2.1 3.5 3 1 0 3 3 2 0 Flagellar protein FliT Med9 PF07544.13 EMC98380.1 - 0.08 13.0 0.6 0.08 13.0 0.6 3.3 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 UPF0242 PF06785.11 EMC98380.1 - 0.081 13.0 23.0 0.99 9.5 11.5 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus 5_nucleotid PF05761.14 EMC98380.1 - 0.11 11.4 6.9 0.85 8.4 0.1 2.1 2 0 0 2 2 2 0 5' nucleotidase family Miff PF05644.11 EMC98380.1 - 0.17 11.5 10.0 0.26 10.9 10.0 1.3 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff ApoLp-III PF07464.11 EMC98380.1 - 0.21 11.6 13.1 0.16 12.0 4.3 2.4 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) BLOC1_2 PF10046.9 EMC98380.1 - 0.23 11.8 15.6 2.9 8.2 5.7 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3987 PF13148.6 EMC98380.1 - 0.23 10.4 9.2 0.13 11.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Dynamitin PF04912.14 EMC98380.1 - 0.24 10.7 19.0 0.46 9.7 19.0 1.4 1 1 0 1 1 1 0 Dynamitin GAS PF13851.6 EMC98380.1 - 0.27 10.6 24.7 0.74 9.1 5.3 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 EMC98380.1 - 0.33 11.1 25.6 0.14 12.2 0.9 4.6 4 2 1 5 5 4 0 bZIP transcription factor Leu_zip PF15294.6 EMC98380.1 - 0.42 10.1 19.1 0.045 13.3 0.9 2.8 2 1 1 3 3 3 0 Leucine zipper DUF4515 PF14988.6 EMC98380.1 - 0.5 10.2 24.2 0.5 10.2 8.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) PCRF PF03462.18 EMC98380.1 - 0.59 10.0 11.3 0.21 11.4 3.0 2.6 3 0 0 3 3 3 0 PCRF domain Phage_GP20 PF06810.11 EMC98380.1 - 0.6 9.9 20.4 0.55 10.0 6.4 3.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF5082 PF16888.5 EMC98380.1 - 0.66 10.3 14.9 2.5 8.4 4.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ADIP PF11559.8 EMC98380.1 - 0.67 10.0 22.1 3.1 7.9 8.2 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 EMC98380.1 - 0.68 10.0 4.9 0.32 11.0 0.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SPT16 PF08644.11 EMC98380.1 - 0.99 9.6 8.5 0.052 13.7 2.1 2.0 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) BRI3BP PF14965.6 EMC98380.1 - 1 8.8 6.3 1.1 8.8 0.4 3.1 2 2 1 3 3 3 0 Negative regulator of p53/TP53 Prominin PF05478.11 EMC98380.1 - 1.5 6.7 6.2 0.59 8.0 1.6 1.9 2 0 0 2 2 2 0 Prominin CLZ PF16526.5 EMC98380.1 - 1.5 9.2 21.0 0.96 9.9 2.3 3.9 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.9 EMC98380.1 - 1.7 8.9 18.3 11 6.2 0.1 5.0 5 0 0 5 5 5 0 Haemolysin XhlA Spc7 PF08317.11 EMC98380.1 - 2.1 7.2 29.0 1.7 7.5 4.9 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 EMC98380.1 - 2.1 8.5 25.3 1.8 8.8 2.6 3.0 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Spc24 PF08286.11 EMC98380.1 - 2.3 8.5 21.4 0.18 12.1 4.5 3.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Shugoshin_N PF07558.11 EMC98380.1 - 2.7 7.9 16.3 8.3 6.4 0.3 4.2 4 1 0 4 4 4 0 Shugoshin N-terminal coiled-coil region ACCA PF03255.14 EMC98380.1 - 3.2 7.6 11.2 0.5 10.2 2.0 2.9 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Swi5 PF07061.11 EMC98380.1 - 3.6 7.7 16.3 1.5 9.0 2.1 3.2 2 1 1 3 3 3 0 Swi5 DivIVA PF05103.13 EMC98380.1 - 3.9 7.6 24.1 1.4 9.0 3.1 3.7 3 1 1 4 4 4 0 DivIVA protein Csm1_N PF18504.1 EMC98380.1 - 4.1 7.8 24.3 0.4 11.0 3.6 4.1 3 2 1 4 4 4 0 Csm1 N-terminal domain Mu-like_Pro PF10123.9 EMC98380.1 - 4.2 6.8 11.4 9.8 5.6 11.4 1.7 1 1 0 1 1 1 0 Mu-like prophage I protein FlaC_arch PF05377.11 EMC98380.1 - 4.3 7.8 21.5 0.46 10.9 4.9 4.0 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.13 EMC98380.1 - 4.4 6.8 14.0 3.9 7.0 1.0 2.7 2 1 1 3 3 3 0 fzo-like conserved region DLP_helical PF18709.1 EMC98380.1 - 4.9 6.3 13.2 7.3 5.7 4.9 2.3 2 0 0 2 2 2 0 Dynamin-like helical domain Vfa1 PF08432.10 EMC98380.1 - 5.2 7.4 9.1 12 6.2 0.4 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.6 EMC98380.1 - 5.8 6.2 18.4 1 8.7 6.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 EMC98380.1 - 9 6.4 32.8 2.2 8.4 6.7 2.5 2 1 0 2 2 2 0 Tropomyosin like GCN5L1 PF06320.13 EMC98380.1 - 9.3 6.4 18.0 0.12 12.5 4.7 2.7 3 0 0 3 3 2 0 GCN5-like protein 1 (GCN5L1) Cnn_1N PF07989.11 EMC98380.1 - 9.4 6.5 19.7 0.19 11.9 3.6 3.4 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 Macoilin PF09726.9 EMC98380.1 - 9.5 4.6 16.1 5 5.6 10.6 2.1 2 0 0 2 2 2 0 Macoilin family TRAM_LAG1_CLN8 PF03798.16 EMC98382.1 - 4e-38 131.1 22.9 4e-38 131.1 22.9 2.0 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.11 EMC98382.1 - 2.2e-18 65.7 3.9 2.6e-18 65.4 0.1 2.6 2 0 0 2 2 2 1 TRAM1-like protein F_bP_aldolase PF01116.20 EMC98383.1 - 2.1e-95 319.4 0.1 2.4e-95 319.2 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Prp19 PF08606.11 EMC98384.1 - 1e-31 108.7 3.2 2.2e-31 107.7 3.2 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EMC98384.1 - 3.5e-18 65.7 0.0 1e-10 41.7 0.0 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMC98384.1 - 1.1e-15 57.7 9.4 0.00057 20.6 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EMC98384.1 - 0.0051 15.4 0.0 0.011 14.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain Frtz PF11768.8 EMC98384.1 - 0.0051 15.2 0.0 0.0091 14.4 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Gmad1 PF10647.9 EMC98384.1 - 0.0053 16.6 3.9 0.35 10.6 1.1 2.7 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain VID27 PF08553.10 EMC98384.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain V_ATPase_I_N PF18670.1 EMC98384.1 - 0.014 15.8 0.1 0.03 14.7 0.1 1.5 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain Ge1_WD40 PF16529.5 EMC98384.1 - 0.031 13.2 0.1 0.067 12.1 0.1 1.5 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein U-box PF04564.15 EMC98384.1 - 0.031 14.4 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain DUF3450 PF11932.8 EMC98384.1 - 0.039 13.3 1.6 0.07 12.4 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HPS3_N PF14761.6 EMC98384.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 zf-Nse PF11789.8 EMC98384.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ABC_tran_CTD PF16326.5 EMC98384.1 - 1 9.7 5.4 0.22 11.8 1.6 1.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain zf-RING_5 PF14634.6 EMC98385.1 - 0.00027 20.8 0.8 0.00049 20.0 0.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EMC98385.1 - 0.0019 18.0 0.6 0.0043 16.9 0.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC98385.1 - 0.0036 17.3 0.4 0.0072 16.3 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EMC98385.1 - 0.0065 16.8 1.0 0.014 15.7 1.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMC98385.1 - 0.014 15.2 2.9 0.042 13.7 2.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMC98385.1 - 0.045 13.6 3.2 0.14 12.0 3.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 EMC98385.1 - 0.082 12.3 0.4 0.42 10.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-IS66 PF13005.7 EMC98385.1 - 0.095 13.1 0.7 1 9.8 0.1 2.5 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF1272 PF06906.11 EMC98385.1 - 0.14 12.2 1.2 9 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Prok-RING_1 PF14446.6 EMC98385.1 - 0.15 12.0 3.6 0.15 12.0 0.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 IBR PF01485.21 EMC98385.1 - 0.37 11.0 5.9 0.13 12.5 1.9 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 EMC98385.1 - 0.38 10.7 2.9 1.8 8.5 3.1 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE PF01363.21 EMC98385.1 - 0.56 10.4 3.5 1.2 9.3 3.5 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-ISL3 PF14690.6 EMC98385.1 - 0.65 10.7 4.1 0.56 10.9 0.2 2.4 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PX PF00787.24 EMC98386.1 - 3.9e-17 62.3 0.2 8e-17 61.2 0.2 1.5 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.9 EMC98386.1 - 0.075 12.2 0.5 0.12 11.5 0.5 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PTPLA PF04387.14 EMC98387.1 - 8.9e-55 184.9 13.5 1.6e-54 184.1 13.5 1.4 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA EbsA PF17255.2 EMC98387.1 - 0.1 12.9 3.1 0.23 11.8 3.1 1.5 1 0 0 1 1 1 0 EbsA-like protein Aha1_N PF09229.11 EMC98388.1 - 4.2e-41 140.4 0.3 6.4e-41 139.8 0.3 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EMC98388.1 - 1.2e-18 67.5 0.2 2.3e-18 66.6 0.2 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EMC98388.1 - 0.0042 17.4 0.8 3.3 8.0 0.3 2.3 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Ras PF00071.22 EMC98390.1 - 1.2e-31 109.5 0.2 1.6e-31 109.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC98390.1 - 8.5e-24 84.1 0.1 1.5e-23 83.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC98390.1 - 7.2e-07 28.8 0.1 8.6e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMC98390.1 - 4.4e-05 22.9 0.2 5.8e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EMC98390.1 - 0.0016 17.4 0.1 0.23 10.2 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 EMC98390.1 - 0.23 10.6 2.9 0.4 9.8 0.1 2.3 1 1 2 3 3 3 0 G-protein alpha subunit Kinetochor_Ybp2 PF08568.10 EMC98391.1 - 2.5e-117 393.0 0.0 3.1e-117 392.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin FAM101 PF15068.6 EMC98392.1 - 0.16 11.9 3.5 0.69 9.8 3.5 2.0 1 1 0 1 1 1 0 FAM101 family MFS_1 PF07690.16 EMC98393.1 - 1.6e-25 89.8 88.1 3.1e-22 79.0 49.9 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMC98393.1 - 1.4e-08 33.6 18.3 1.9e-08 33.2 18.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMC98393.1 - 0.0012 17.7 4.8 0.0012 17.7 4.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Ysc84 PF04366.12 EMC98393.1 - 0.011 15.5 0.4 0.057 13.2 0.1 2.0 2 0 0 2 2 2 0 Las17-binding protein actin regulator Zn_peptidase_2 PF04298.12 EMC98393.1 - 1.5 8.2 6.3 1.1 8.6 0.0 2.8 3 0 0 3 3 3 0 Putative neutral zinc metallopeptidase ADH_N PF08240.12 EMC98394.1 - 6.1e-18 64.7 0.2 1e-17 63.9 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.7 EMC98395.1 - 4.7e-06 26.4 0.4 1.2e-05 25.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC98395.1 - 9.2e-06 25.4 0.8 2.2e-05 24.2 0.8 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EMC98395.1 - 0.0041 17.0 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 F-box Raptor_N PF14538.6 EMC98396.1 - 1.1e-61 207.1 0.0 2e-61 206.3 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EMC98396.1 - 3.9e-09 37.0 4.2 2.1 9.3 0.0 7.4 9 0 0 9 9 9 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 EMC98396.1 - 0.00013 22.0 0.2 0.071 13.1 0.0 3.4 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 EMC98396.1 - 0.00083 19.4 5.0 0.15 12.4 0.1 4.7 5 0 0 5 5 5 1 HEAT repeat Atx10homo_assoc PF09759.9 EMC98396.1 - 0.018 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain BPL_C PF02237.17 EMC98397.1 - 0.13 12.2 0.0 0.57 10.1 0.0 1.8 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain CRIM PF16978.5 EMC98401.1 - 2.8e-34 118.3 0.0 4.6e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EMC98401.1 - 9.7e-20 70.9 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PBP1_TM PF14812.6 EMC98401.1 - 0.94 9.9 12.9 2.9 8.3 2.6 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal adh_short PF00106.25 EMC98402.1 - 1.6e-10 40.7 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC98402.1 - 1.8e-09 37.8 0.0 2.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EMC98402.1 - 7.4e-07 29.0 0.0 9e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Spc7 PF08317.11 EMC98403.1 - 2.3e-05 23.4 7.8 0.0041 16.0 1.0 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein COG2 PF06148.11 EMC98403.1 - 0.001 19.2 2.6 0.079 13.1 0.2 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.9 EMC98403.1 - 0.0016 18.7 5.5 0.056 13.8 1.1 2.3 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 EMC98403.1 - 0.0022 18.3 4.7 0.098 13.1 0.2 3.1 2 1 0 3 3 3 1 Flagella accessory protein C (FlaC) Fez1 PF06818.15 EMC98403.1 - 0.0071 16.8 11.5 0.24 11.8 2.1 2.2 1 1 1 2 2 2 2 Fez1 Tropomyosin_1 PF12718.7 EMC98403.1 - 0.0072 16.5 10.1 0.37 10.9 3.0 2.2 1 1 1 2 2 2 2 Tropomyosin like ZapB PF06005.12 EMC98403.1 - 0.01 16.2 1.0 0.01 16.2 1.0 3.2 2 1 0 2 2 2 0 Cell division protein ZapB AAA_13 PF13166.6 EMC98403.1 - 0.013 14.1 0.3 0.018 13.7 0.3 1.1 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 EMC98403.1 - 0.016 15.7 1.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 EMC98403.1 - 0.03 14.6 0.7 0.03 14.6 0.7 3.7 3 1 0 3 3 3 0 ABC transporter C-terminal domain Med9 PF07544.13 EMC98403.1 - 0.033 14.3 1.0 0.033 14.3 1.0 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 USP8_interact PF08941.10 EMC98403.1 - 0.053 13.3 1.4 0.89 9.3 0.1 2.2 2 0 0 2 2 2 0 USP8 interacting CENP-F_N PF10481.9 EMC98403.1 - 0.055 13.1 2.9 0.077 12.6 2.9 1.3 1 0 0 1 1 1 0 Cenp-F N-terminal domain ATG16 PF08614.11 EMC98403.1 - 0.072 13.3 12.3 0.2 11.8 2.7 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 EMC98403.1 - 0.095 13.3 3.0 1.8 9.2 0.2 2.4 2 0 0 2 2 2 0 Initiation control protein YabA DUF1192 PF06698.11 EMC98403.1 - 0.11 12.5 7.0 0.5 10.4 0.1 3.5 4 0 0 4 4 2 0 Protein of unknown function (DUF1192) Atg14 PF10186.9 EMC98403.1 - 0.12 11.5 10.7 1.6 7.8 10.6 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 EMC98403.1 - 0.14 12.7 6.9 3.7 8.1 0.6 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF16 COG5 PF10392.9 EMC98403.1 - 0.15 12.3 2.2 2 8.6 0.2 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 IFT57 PF10498.9 EMC98403.1 - 0.15 11.0 4.2 3 6.7 0.2 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Prefoldin_2 PF01920.20 EMC98403.1 - 0.15 12.0 9.8 0.97 9.4 0.4 3.2 2 1 1 3 3 3 0 Prefoldin subunit DivIC PF04977.15 EMC98403.1 - 0.17 11.7 13.3 0.56 10.0 3.6 3.1 2 1 1 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 EMC98403.1 - 0.18 11.1 8.9 0.52 9.6 8.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.6 EMC98403.1 - 0.19 11.1 9.1 1.4 8.2 1.2 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 EMC98403.1 - 0.22 10.9 8.3 0.35 10.3 8.3 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 EMC98403.1 - 0.29 11.2 5.7 3.9 7.5 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II OmpH PF03938.14 EMC98403.1 - 0.31 11.4 9.7 2.5 8.4 2.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5082 PF16888.5 EMC98403.1 - 0.32 11.3 8.7 1.9 8.8 1.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 EMC98403.1 - 0.33 11.1 2.1 18 5.5 0.2 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 EMC98403.1 - 0.35 10.4 6.7 0.57 9.7 6.7 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Osmo_CC PF08946.10 EMC98403.1 - 0.43 10.9 9.8 0.16 12.2 1.8 3.4 2 2 1 3 3 3 0 Osmosensory transporter coiled coil Syntaxin-6_N PF09177.11 EMC98403.1 - 0.57 10.8 5.8 7.5 7.2 0.5 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 EMC98403.1 - 0.59 10.2 14.5 0.56 10.3 3.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 EMC98403.1 - 0.67 9.6 8.1 3.4 7.3 2.3 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4201 PF13870.6 EMC98403.1 - 1 9.1 8.1 33 4.2 8.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF3552 PF12072.8 EMC98403.1 - 1 8.7 13.8 1.6 8.1 2.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) YkyA PF10368.9 EMC98403.1 - 1.1 8.9 8.3 1.9 8.1 1.3 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Baculo_PEP_C PF04513.12 EMC98403.1 - 1.3 9.1 4.1 17 5.4 4.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 EMC98403.1 - 1.3 8.3 11.0 3 7.1 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF641 PF04859.12 EMC98403.1 - 1.8 8.9 7.5 0.93 9.8 0.7 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ADIP PF11559.8 EMC98403.1 - 1.8 8.6 13.9 0.93 9.6 3.6 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 EMC98403.1 - 1.8 8.4 13.4 4 7.2 10.8 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Prefoldin PF02996.17 EMC98403.1 - 2.1 8.3 10.6 7.9 6.4 0.3 3.1 2 1 1 3 3 3 0 Prefoldin subunit FUSC PF04632.12 EMC98403.1 - 2.1 6.8 7.7 2.8 6.4 7.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FliJ PF02050.16 EMC98403.1 - 2.1 8.6 13.3 1.4 9.1 3.3 2.6 3 0 0 3 3 2 0 Flagellar FliJ protein TolA_bind_tri PF16331.5 EMC98403.1 - 2.2 8.4 17.7 0.28 11.3 4.3 3.2 2 1 1 3 3 3 0 TolA binding protein trimerisation AAA_lid_9 PF17871.1 EMC98403.1 - 2.5 8.0 5.0 2.9 7.9 0.8 2.4 2 1 0 2 2 2 0 AAA lid domain DUF812 PF05667.11 EMC98403.1 - 2.8 6.7 12.0 1.4 7.7 3.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Csm1_N PF18504.1 EMC98403.1 - 3 8.2 15.0 7.9 6.9 0.7 3.7 2 2 1 3 3 3 0 Csm1 N-terminal domain TSC22 PF01166.18 EMC98403.1 - 3.4 8.0 8.9 11 6.4 0.1 3.2 2 2 0 2 2 2 0 TSC-22/dip/bun family LPP PF04728.13 EMC98403.1 - 4.8 7.6 5.7 83 3.7 3.0 3.0 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF3584 PF12128.8 EMC98403.1 - 5.1 4.5 14.4 1.6 6.2 5.4 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) BRE1 PF08647.11 EMC98403.1 - 5.4 7.2 11.4 0.32 11.1 2.3 2.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF2203 PF09969.9 EMC98403.1 - 9 7.0 7.8 12 6.7 1.2 2.5 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PHD PF00628.29 EMC98405.1 - 5.7e-05 22.9 13.3 5.7e-05 22.9 13.3 2.0 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 EMC98405.1 - 0.01 16.0 7.3 0.021 15.0 7.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Lipase_GDSL_2 PF13472.6 EMC98407.1 - 1.4e-19 71.1 1.9 2.6e-19 70.3 1.9 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EMC98407.1 - 7.8e-10 39.1 0.1 1.3e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ribosomal_L37e PF01907.19 EMC98408.1 - 3.5e-25 87.9 12.6 5.8e-25 87.2 12.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EMC98408.1 - 0.0047 16.9 1.9 0.0072 16.3 1.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 EMC98408.1 - 0.023 14.7 1.0 0.032 14.3 1.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 EMC98408.1 - 0.14 11.9 5.0 2.6 7.9 5.4 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 EMC98408.1 - 0.26 11.1 3.9 2.5 7.9 0.4 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-ribbon_3 PF13248.6 EMC98408.1 - 0.3 10.5 3.4 0.68 9.4 3.4 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_6 PF14599.6 EMC98408.1 - 0.4 10.7 3.8 0.64 10.1 3.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon zf_UBZ PF18439.1 EMC98408.1 - 2 8.1 4.1 2.6 7.7 0.2 2.1 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger GST_N_2 PF13409.6 EMC98409.1 - 8e-21 74.1 0.0 1.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMC98409.1 - 3.5e-12 46.1 0.0 1e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMC98409.1 - 1.1e-05 25.6 0.1 2.3e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMC98409.1 - 1.5e-05 25.2 0.1 4.7e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain BPL_LplA_LipB PF03099.19 EMC98410.1 - 2.5e-07 30.6 0.0 3.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Rpp20 PF12328.8 EMC98411.1 - 1.4e-31 109.3 12.7 1.1e-29 103.1 12.7 3.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EMC98411.1 - 2.4e-10 40.1 0.0 4.1e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 Alba Med11 PF10280.9 EMC98411.1 - 0.011 16.2 0.3 0.022 15.2 0.3 1.6 1 0 0 1 1 1 0 Mediator complex protein PX PF00787.24 EMC98412.1 - 2e-24 85.7 0.0 2.5e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 PX domain WD40 PF00400.32 EMC98413.1 - 1.8e-11 44.4 7.8 0.00028 21.6 0.1 5.5 5 1 1 6 6 6 2 WD domain, G-beta repeat Frtz PF11768.8 EMC98413.1 - 0.00012 20.6 0.2 0.00053 18.4 0.0 2.0 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 EMC98413.1 - 0.00014 21.6 5.4 0.036 13.7 0.5 3.0 2 1 1 3 3 3 2 PQQ-like domain ANAPC4_WD40 PF12894.7 EMC98413.1 - 0.00022 21.5 0.3 0.022 15.1 0.1 3.5 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EMC98413.1 - 0.003 18.0 1.3 35 5.1 0.1 4.8 5 0 0 5 5 5 0 PQQ-like domain Nup160 PF11715.8 EMC98413.1 - 0.004 15.9 4.9 0.27 9.8 0.1 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EMC98413.1 - 0.04 12.7 0.1 0.33 9.7 0.0 2.4 1 1 1 2 2 2 0 Nup133 N terminal like UBX PF00789.20 EMC98415.1 - 3.3e-09 36.8 0.0 6.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain Caldesmon PF02029.15 EMC98415.1 - 3.8e-05 22.7 13.3 6.2e-05 22.0 13.3 1.3 1 0 0 1 1 1 1 Caldesmon Borrelia_P83 PF05262.11 EMC98415.1 - 0.0047 15.5 10.1 0.0073 14.8 10.1 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein MAJIN PF15077.6 EMC98415.1 - 4.1 7.1 14.7 6.8 6.4 14.7 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein HD-ZIP_N PF04618.12 EMC98415.1 - 5.1 7.6 6.0 7.2 7.2 2.5 2.8 3 1 0 3 3 3 0 HD-ZIP protein N terminus SURF1 PF02104.15 EMC98416.1 - 1.7e-44 152.2 0.6 3.6e-44 151.1 0.1 1.7 2 0 0 2 2 2 1 SURF1 family RmlD_sub_bind PF04321.17 EMC98416.1 - 0.051 12.7 0.2 0.071 12.2 0.2 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain PCI PF01399.27 EMC98417.1 - 3.9e-19 69.1 0.0 8.6e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EMC98417.1 - 4.1e-15 55.6 0.2 9.8e-15 54.4 0.2 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain TPR_20 PF14561.6 EMC98417.1 - 0.069 13.5 0.3 0.39 11.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CMS1 PF14617.6 EMC98418.1 - 9.5e-80 267.6 5.0 1.1e-79 267.4 5.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EMC98418.1 - 9.7e-05 22.2 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase tRNA-synt_2 PF00152.20 EMC98420.1 - 3.2e-69 233.4 0.0 4.4e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMC98420.1 - 1.9e-08 34.1 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMC98420.1 - 0.034 13.6 0.1 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Rtf2 PF04641.12 EMC98420.1 - 0.057 12.8 1.5 0.095 12.0 1.5 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger tRNA_anti_2 PF13742.6 EMC98420.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain adh_short_C2 PF13561.6 EMC98421.1 - 3.9e-53 180.4 0.0 7.2e-53 179.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC98421.1 - 2.2e-41 141.5 0.2 6.3e-41 140.0 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC98421.1 - 3.7e-05 23.7 0.1 8.2e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC98421.1 - 0.0069 15.9 0.0 0.019 14.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EMC98421.1 - 0.019 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 EMC98421.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1445 PF07286.12 EMC98421.1 - 0.095 12.6 0.0 0.49 10.3 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1445) SCO1-SenC PF02630.14 EMC98423.1 - 2.2e-49 166.8 0.0 3.1e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EMC98423.1 - 1.5e-06 28.1 0.0 2.7e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EMC98423.1 - 0.001 19.4 0.0 0.0018 18.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EMC98423.1 - 0.0046 16.7 0.0 0.032 13.9 0.0 1.9 1 1 0 1 1 1 1 Redoxin FBPase PF00316.20 EMC98424.1 - 4.2e-71 238.4 0.0 5.3e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain SET PF00856.28 EMC98425.1 - 2e-12 47.8 0.0 6.9e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 EMC98425.1 - 0.00017 21.2 6.6 0.028 14.2 0.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EMC98425.1 - 0.0022 18.0 8.4 0.5 10.6 0.3 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMC98425.1 - 5.5 7.7 9.7 1.4 9.6 4.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.20 EMC98426.1 - 5.6e-24 84.1 0.0 7.5e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EMC98426.1 - 0.00038 19.9 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EMC98426.1 - 0.00043 20.7 0.1 0.0017 18.8 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EMC98426.1 - 0.00076 19.8 0.0 0.025 14.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EMC98426.1 - 0.0069 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EMC98426.1 - 0.009 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EMC98426.1 - 0.037 13.9 0.1 0.11 12.4 0.1 1.7 1 1 1 2 2 2 0 AhpC/TSA family HET PF06985.11 EMC98427.1 - 4.5e-35 121.1 0.7 7.6e-35 120.4 0.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.21 EMC98428.1 - 8.6e-62 209.0 0.0 9.7e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 EMC98429.1 - 5e-26 90.7 0.6 1e-25 89.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC98429.1 - 4.8e-25 88.0 0.0 7.4e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMC98429.1 - 2.3e-07 30.5 0.0 3.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMC98429.1 - 1.5e-05 26.1 0.0 2.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 EMC98429.1 - 0.0013 19.2 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EMC98429.1 - 0.024 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 EMC98429.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 EMC98429.1 - 0.094 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EMC98429.1 - 0.11 13.0 0.4 0.36 11.4 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_1 PF00561.20 EMC98431.1 - 7.3e-15 55.3 0.0 8.6e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC98431.1 - 1.3e-14 54.0 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMC98431.1 - 5.1e-12 46.9 0.0 6.4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EMC98431.1 - 1.3e-06 28.7 0.1 1.4e-05 25.4 0.1 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 EMC98431.1 - 0.00048 19.9 0.0 0.0013 18.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family zf-C2HC PF01530.18 EMC98431.1 - 0.057 13.6 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2HC type PBP PF01161.20 EMC98435.1 - 4.8e-09 36.6 0.0 5.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Lactamase_B_2 PF12706.7 EMC98436.1 - 1.4e-24 86.8 0.2 5.6e-22 78.3 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMC98436.1 - 6.1e-05 23.0 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.18 EMC98438.1 - 2.8e-16 59.3 0.0 4.5e-16 58.7 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC98438.1 - 7.7e-06 25.9 11.4 1.3e-05 25.3 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arm_vescicular PF18770.1 EMC98438.1 - 0.079 12.9 0.9 0.28 11.1 0.9 1.9 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor WD40 PF00400.32 EMC98439.1 - 1.5e-35 120.6 15.8 0.00031 21.5 0.1 11.4 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC98439.1 - 5e-09 36.3 4.1 0.89 9.9 0.1 7.4 5 1 4 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4596 PF15363.6 EMC98439.1 - 0.073 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Urm1 PF09138.11 EMC98440.1 - 2.5e-36 123.9 0.0 2.8e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EMC98440.1 - 0.00016 22.2 0.0 0.00019 22.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family Fasciclin PF02469.22 EMC98441.1 - 2.8e-46 156.9 2.5 2.4e-26 92.5 0.1 2.5 2 1 0 2 2 2 2 Fasciclin domain Histone_H2A_C PF16211.5 EMC98441.1 - 0.33 10.7 2.3 2.2 8.1 0.0 3.1 3 0 0 3 3 3 0 C-terminus of histone H2A Ras PF00071.22 EMC98443.1 - 5.3e-56 188.7 0.0 6.6e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC98443.1 - 3.2e-31 108.1 0.0 4.9e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC98443.1 - 1.1e-11 44.6 0.0 1.2e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EMC98443.1 - 1.3e-07 31.7 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EMC98443.1 - 1.1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMC98443.1 - 3.9e-05 23.3 0.0 0.0018 17.8 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMC98443.1 - 9.2e-05 22.4 0.0 0.004 17.1 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 EMC98443.1 - 0.00076 19.3 0.2 0.021 14.6 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 EMC98443.1 - 0.002 17.7 0.0 0.029 14.0 0.0 2.1 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EMC98443.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC98443.1 - 0.0083 16.5 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 EMC98443.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EMC98443.1 - 0.012 15.4 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EMC98443.1 - 0.012 15.9 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMC98443.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EMC98443.1 - 0.027 14.0 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EMC98443.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Septin NB-ARC PF00931.22 EMC98443.1 - 0.054 12.7 0.0 0.3 10.2 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EMC98443.1 - 0.08 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EMC98443.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 EMC98443.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 EMC98443.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase JAB PF01398.21 EMC98444.1 - 5.9e-29 100.4 0.3 1.5e-28 99.2 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EMC98444.1 - 6.3e-20 71.9 0.1 1.4e-19 70.7 0.1 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EMC98444.1 - 1.7e-06 27.8 0.1 1.3e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EMC98444.1 - 0.01 15.9 0.1 0.026 14.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Apt1 PF10351.9 EMC98445.1 - 1.4e-190 634.2 1.2 1.4e-190 634.2 1.2 2.1 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27 PF10344.9 EMC98445.1 - 5.9e-178 593.8 0.0 7.9e-178 593.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 EMC98445.1 - 7e-176 585.8 5.6 1.5e-175 584.7 5.6 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EMC98445.1 - 1.8e-57 193.8 0.4 5.6e-57 192.2 0.0 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EMC98445.1 - 1e-54 184.6 0.8 2.6e-54 183.3 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EMC98445.1 - 4.3e-33 114.1 0.6 1.1e-31 109.6 0.0 3.4 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF1043 PF06295.12 EMC98445.1 - 6.6 6.7 12.4 1.7 8.7 6.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) IF3_N PF05198.16 EMC98446.1 - 2.7e-07 30.7 0.0 4.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 EMC98446.1 - 8.2e-07 28.9 0.1 0.0001 22.1 0.1 2.2 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_C PF00707.22 EMC98446.1 - 4.3e-05 23.4 0.1 8.4e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Spc29 PF17082.5 EMC98446.1 - 0.0029 17.5 0.1 0.0051 16.7 0.1 1.4 1 0 0 1 1 1 1 Spindle Pole Component 29 tRNA-synt_1c PF00749.21 EMC98447.1 - 5.2e-87 291.7 0.0 7.2e-87 291.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Nup54 PF13874.6 EMC98447.1 - 1.7 8.7 4.5 2.6 8.1 0.6 2.7 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DnaJ_C PF01556.18 EMC98448.1 - 4.8e-36 124.1 0.0 7.1e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EMC98448.1 - 8.9e-21 73.8 1.9 1.4e-20 73.2 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EMC98448.1 - 2.7e-13 50.1 16.7 5.1e-13 49.2 16.7 1.5 1 0 0 1 1 1 1 DnaJ central domain HflK_N PF12221.8 EMC98448.1 - 0.002 18.1 1.9 0.0076 16.2 1.9 2.0 1 0 0 1 1 1 1 Bacterial membrane protein N terminal Cytochrom_c3_2 PF14537.6 EMC98448.1 - 0.052 14.0 2.0 10 6.7 0.2 2.3 2 0 0 2 2 2 0 Cytochrome c3 Anti-TRAP PF15777.5 EMC98448.1 - 1.5 8.8 16.1 1.2 9.1 4.8 2.9 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EMC98448.1 - 1.8 8.6 7.6 11 6.1 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 EMC98448.1 - 2.5 7.3 6.4 2.8 7.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zf-MYND PF01753.18 EMC98449.1 - 3.5e-08 33.4 18.5 1e-07 31.9 18.5 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EMC98449.1 - 7.1 6.6 10.1 16 5.5 10.1 1.6 1 0 0 1 1 1 0 HIT zinc finger Ribosomal_L4 PF00573.22 EMC98452.1 - 4.7e-44 150.4 0.0 6.1e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF2625 PF10946.8 EMC98452.1 - 0.068 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2625 PBP PF01161.20 EMC98453.1 - 1.5e-05 25.3 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4061 PF13270.6 EMC98453.1 - 0.17 12.2 1.4 0.34 11.3 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) EXOSC1 PF10447.9 EMC98454.1 - 5.5e-20 72.0 0.4 1.6e-13 51.2 0.2 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EMC98454.1 - 1.5e-06 27.9 0.0 2.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PixA PF12306.8 EMC98454.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Inclusion body protein CorA PF01544.18 EMC98455.1 - 3.3e-24 85.7 9.8 2.1e-18 66.7 0.6 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein NADH_dehy_S2_C PF06444.11 EMC98455.1 - 3.3 8.3 6.5 3.4 8.3 1.0 2.7 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus ATG16 PF08614.11 EMC98456.1 - 9.8e-56 189.2 24.3 1.1e-55 189.0 24.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EMC98456.1 - 9.3e-05 22.0 11.5 0.0001 21.9 11.5 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Lebercilin PF15619.6 EMC98456.1 - 0.001 18.7 17.0 0.0017 18.0 17.0 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease FPP PF05911.11 EMC98456.1 - 0.002 16.5 10.6 0.0024 16.2 10.6 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF4201 PF13870.6 EMC98456.1 - 0.0021 17.8 10.2 0.0036 17.1 10.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) YlqD PF11068.8 EMC98456.1 - 0.0031 17.9 10.6 0.0055 17.1 10.6 1.4 1 0 0 1 1 1 1 YlqD protein GAS PF13851.6 EMC98456.1 - 0.0037 16.7 15.8 0.0052 16.2 15.1 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding ADIP PF11559.8 EMC98456.1 - 0.0041 17.2 14.4 0.0065 16.6 14.4 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 EMC98456.1 - 0.0077 15.2 12.1 0.0088 15.0 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) BLOC1_2 PF10046.9 EMC98456.1 - 0.02 15.1 5.1 0.33 11.3 5.6 2.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 JIP_LZII PF16471.5 EMC98456.1 - 0.039 14.1 8.1 1.3 9.3 4.4 3.0 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II KELK PF15796.5 EMC98456.1 - 0.073 13.5 16.2 0.28 11.7 7.2 3.5 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FAM76 PF16046.5 EMC98456.1 - 0.076 12.4 14.7 0.14 11.5 14.7 1.3 1 1 0 1 1 1 0 FAM76 protein Mei5 PF10376.9 EMC98456.1 - 0.086 12.7 14.3 0.48 10.2 14.3 1.9 1 1 0 1 1 1 0 Double-strand recombination repair protein BRE1 PF08647.11 EMC98456.1 - 0.15 12.2 16.7 0.85 9.7 14.6 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Phage_GP20 PF06810.11 EMC98456.1 - 0.32 10.8 8.9 0.6 9.9 8.5 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 Exonuc_VII_L PF02601.15 EMC98456.1 - 0.4 10.2 12.8 0.62 9.6 12.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 EMC98456.1 - 0.46 11.0 21.6 0.27 11.8 17.9 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 EMC98456.1 - 0.54 9.1 17.2 0.064 12.1 11.1 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 EMC98456.1 - 0.74 8.4 8.5 0.99 8.0 8.4 1.3 1 1 0 1 1 1 0 AAA domain DUF2968 PF11180.8 EMC98456.1 - 0.77 9.4 19.5 0.027 14.1 9.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) DivIC PF04977.15 EMC98456.1 - 0.81 9.5 17.6 0.57 10.0 1.4 3.2 1 1 2 3 3 3 0 Septum formation initiator DUF1664 PF07889.12 EMC98456.1 - 0.99 9.5 7.9 18 5.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 EMC98456.1 - 1.2 8.8 13.3 1.4 8.6 12.4 1.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 SlyX PF04102.12 EMC98456.1 - 1.5 9.5 18.2 1 10.0 1.9 3.3 1 1 2 3 3 3 0 SlyX HAUS-augmin3 PF14932.6 EMC98456.1 - 1.5 8.3 16.0 3.4 7.2 15.9 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 EMC98456.1 - 1.6 8.0 19.3 0.22 10.9 15.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EMC98456.1 - 2.3 8.3 16.1 32 4.5 16.1 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 EMC98456.1 - 2.7 8.1 17.0 0.66 10.0 1.5 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 EMC98456.1 - 3.2 8.2 17.7 15 6.0 11.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 EMC98456.1 - 3.7 6.8 19.5 10 5.3 18.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SseC PF04888.12 EMC98456.1 - 5.3 6.5 12.5 6.9 6.2 2.1 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family E2F_CC-MB PF16421.5 EMC98456.1 - 5.4 7.5 7.3 53 4.3 6.6 2.7 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain ERM PF00769.19 EMC98456.1 - 5.6 6.7 26.1 1.3 8.7 14.7 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-H PF05837.12 EMC98456.1 - 9.2 6.7 20.2 1.8 9.0 9.7 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Glyco_hydro_76 PF03663.14 EMC98457.1 - 4.6e-28 98.8 7.7 5.6e-19 68.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Sugar_tr PF00083.24 EMC98459.1 - 1.1e-107 360.7 23.8 1.3e-107 360.5 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC98459.1 - 2.1e-31 109.2 44.9 1.3e-28 99.9 25.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EMC98459.1 - 0.00056 18.9 0.4 0.0014 17.6 0.4 1.6 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 EMC98459.1 - 0.00065 18.2 1.0 0.0014 17.2 1.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 EMC98459.1 - 0.099 12.9 6.1 0.22 11.8 2.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Phage_holin_3_2 PF04550.12 EMC98459.1 - 0.64 10.6 4.2 0.35 11.4 0.7 2.3 2 0 0 2 2 2 0 Phage holin family 2 ATP13 PF12921.7 EMC98460.1 - 2.3e-25 88.7 0.0 5e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 EMC98460.1 - 0.00075 19.5 0.0 3.4 7.8 0.0 3.3 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EMC98460.1 - 0.11 12.7 0.0 13 6.1 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family LSM PF01423.22 EMC98461.1 - 4.6e-19 67.9 0.0 5.6e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EMC98461.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 RimP C-terminal SH3 domain CHZ PF09649.10 EMC98462.1 - 0.0032 16.9 0.2 0.0032 16.9 0.2 2.1 2 0 0 2 2 2 1 Histone chaperone domain CHZ Zn_clus PF00172.18 EMC98462.1 - 0.0039 17.3 13.0 0.0072 16.4 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 EMC98463.1 - 7.9e-43 145.2 0.0 1.7e-42 144.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMC98463.1 - 1.8e-33 115.1 0.1 4.5e-33 113.9 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain GP24_25 PF17388.2 EMC98463.1 - 0.036 14.1 0.1 0.076 13.0 0.1 1.5 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 adh_short_C2 PF13561.6 EMC98464.1 - 1.5e-54 185.0 0.3 2e-54 184.6 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC98464.1 - 2.6e-45 154.3 1.1 3.3e-45 153.9 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC98464.1 - 2.9e-13 50.1 0.6 3.8e-13 49.7 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC98464.1 - 0.0097 15.4 0.1 0.21 11.0 0.1 2.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 EMC98464.1 - 0.021 14.9 0.2 0.039 14.0 0.2 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N_2 PF13602.6 EMC98464.1 - 0.044 14.8 0.0 0.56 11.3 0.0 2.2 1 1 1 2 2 2 0 Zinc-binding dehydrogenase TIR PF01582.20 EMC98464.1 - 0.052 13.4 0.2 0.073 12.9 0.2 1.2 1 0 0 1 1 1 0 TIR domain Spb1_C PF07780.12 EMC98465.1 - 9.2e-74 247.6 12.2 9.2e-74 247.6 12.2 3.2 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EMC98465.1 - 2.6e-54 184.0 0.0 5.5e-54 182.9 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EMC98465.1 - 3.5e-51 173.3 7.7 3.5e-51 173.3 7.7 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) AAA PF00004.29 EMC98466.1 - 9.6e-09 35.8 1.1 5.4e-08 33.3 1.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMC98466.1 - 2.9e-06 27.8 0.0 9.8e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EMC98466.1 - 7.5e-05 22.7 0.0 0.52 10.2 0.0 3.3 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_22 PF13401.6 EMC98466.1 - 0.0023 18.2 2.6 0.0041 17.4 0.4 2.5 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 EMC98466.1 - 0.005 16.1 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EMC98466.1 - 0.016 15.8 0.0 0.13 12.8 0.0 2.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EMC98466.1 - 0.05 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Glyco_hydro_92 PF07971.12 EMC98467.1 - 1.8e-141 472.2 6.8 2.2e-141 471.9 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EMC98467.1 - 1.7e-51 175.5 2.8 2.9e-51 174.7 2.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Dynamin_N PF00350.23 EMC98468.1 - 1.7e-45 155.1 0.0 3.3e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EMC98468.1 - 1e-10 41.3 0.1 2.6e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EMC98468.1 - 9.4e-05 22.5 0.0 0.0003 20.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EMC98468.1 - 0.017 15.5 1.3 0.1 12.9 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 EMC98468.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 EMC98468.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Senescence PF06911.12 EMC98468.1 - 0.46 10.8 2.1 4.1 7.7 0.2 2.5 2 0 0 2 2 2 0 Senescence-associated protein NMT1 PF09084.11 EMC98469.1 - 3.7e-05 23.8 0.0 0.00026 21.0 0.0 2.0 2 0 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EMC98469.1 - 0.00064 19.2 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EMC98469.1 - 0.058 13.0 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.16 EMC98470.1 - 1e-35 123.3 33.3 1e-35 123.3 33.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98470.1 - 1.3e-12 47.4 10.9 1.3e-12 47.4 10.9 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter Cornichon PF03311.14 EMC98470.1 - 0.012 16.0 0.1 1.5 9.2 0.1 2.9 2 1 0 2 2 2 0 Cornichon protein DUF4407 PF14362.6 EMC98470.1 - 2.9 7.2 5.0 0.47 9.8 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SurE PF01975.17 EMC98471.1 - 3.8e-50 170.4 0.0 4.9e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_4 PF13439.6 EMC98471.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Sugar_tr PF00083.24 EMC98473.1 - 1.6e-96 323.9 26.6 1.9e-96 323.7 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC98473.1 - 1.9e-17 63.2 29.7 1.9e-17 63.2 29.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Cullin PF00888.22 EMC98474.1 - 5.4e-174 580.2 0.0 6.6e-174 579.9 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EMC98474.1 - 2.7e-20 72.2 0.2 6.6e-20 70.9 0.2 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Peripla_BP_4 PF13407.6 EMC98474.1 - 0.013 15.1 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein domain CRCB PF02537.15 EMC98475.1 - 3.7e-35 120.1 12.8 2.4e-21 75.8 8.2 2.7 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) 5TM-5TMR_LYT PF07694.12 EMC98475.1 - 9 5.8 12.5 0.17 11.4 1.6 3.3 3 1 0 3 3 3 0 5TMR of 5TMR-LYT UPRTase PF14681.6 EMC98476.1 - 6.7e-69 231.5 0.0 7.7e-69 231.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EMC98476.1 - 6.6e-07 29.0 0.1 2e-06 27.4 0.2 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EMC98476.1 - 0.088 12.8 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 Phosphoribosyl synthetase-associated domain YajC PF02699.15 EMC98477.1 - 0.06 13.2 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Abhydrolase_6 PF12697.7 EMC98478.1 - 0.00013 22.7 0.1 0.00018 22.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC98478.1 - 0.00064 19.4 0.0 0.002 17.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold NAD_binding_8 PF13450.6 EMC98478.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NEL PF14496.6 EMC98478.1 - 0.22 10.9 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting PalH PF08733.10 EMC98479.1 - 1.2e-95 320.3 0.3 1.4e-95 320.1 0.3 1.0 1 0 0 1 1 1 1 PalH/RIM21 DMA PF03474.14 EMC98479.1 - 0.12 12.0 0.2 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 DMRTA motif Snf7 PF03357.21 EMC98480.1 - 3.6e-45 153.7 15.2 4.2e-45 153.4 15.2 1.0 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.8 EMC98480.1 - 0.00038 18.1 7.5 0.00048 17.8 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CLZ PF16526.5 EMC98480.1 - 0.021 15.2 0.0 0.021 15.2 0.0 3.4 3 1 1 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 EMC98480.1 - 0.054 14.0 6.8 2.4 8.7 0.8 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 EMC98480.1 - 0.078 12.5 4.0 0.092 12.3 4.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Endotoxin_N PF03945.14 EMC98480.1 - 0.15 11.7 4.7 2 8.1 0.3 2.1 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain CorA PF01544.18 EMC98480.1 - 0.16 11.2 1.9 1.9 7.7 1.6 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Allexi_40kDa PF05549.11 EMC98480.1 - 0.38 10.2 3.1 1.7 8.1 0.2 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1319 PF07028.11 EMC98480.1 - 0.6 10.4 3.5 0.49 10.6 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) FliJ PF02050.16 EMC98480.1 - 0.6 10.3 12.3 1.4 9.1 12.3 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein DASH_Spc19 PF08287.11 EMC98480.1 - 0.64 9.9 8.0 3.1 7.7 8.0 2.0 1 1 0 1 1 1 0 Spc19 Zwint PF15556.6 EMC98480.1 - 0.67 9.4 12.1 1.6 8.2 12.1 1.6 1 1 1 2 2 2 0 ZW10 interactor FlaC_arch PF05377.11 EMC98480.1 - 0.95 9.9 8.1 5.1 7.6 0.1 3.5 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 EMC98480.1 - 1.5 9.2 20.5 31 5.0 20.5 2.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2120 PF09893.9 EMC98480.1 - 1.8 8.7 6.2 1.3 9.1 3.8 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Atg14 PF10186.9 EMC98480.1 - 3.2 6.8 9.1 1.6 7.7 5.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SKG6 PF08693.10 EMC98481.1 - 0.021 14.3 4.4 0.036 13.5 4.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sh_2 PF17512.2 EMC98481.1 - 0.063 13.0 6.1 0.37 10.5 1.6 2.5 2 0 0 2 2 2 0 Metapneumovirus Small hydrophobic protein DUF1003 PF06210.11 EMC98481.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) GTP_EFTU PF00009.27 EMC98482.1 - 1.8e-18 66.8 0.0 3.2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EMC98482.1 - 6.4e-10 39.3 0.9 1.1e-08 35.3 0.5 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EMC98482.1 - 0.00012 22.3 0.0 0.00038 20.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EMC98482.1 - 0.0045 17.0 0.1 0.013 15.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EMC98482.1 - 0.021 14.6 0.4 3.5 7.4 0.1 3.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EMC98482.1 - 0.041 13.8 0.4 11 5.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 EMC98482.1 - 0.21 11.8 0.2 2.4 8.4 0.1 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EMC98482.1 - 0.23 11.5 1.7 0.87 9.6 0.7 2.3 2 0 0 2 2 2 0 Dynamin family eIF-3c_N PF05470.12 EMC98482.1 - 0.24 9.6 0.2 1.1 7.5 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HAGH_C PF16123.5 EMC98483.1 - 3.4e-20 72.3 0.6 6.4e-20 71.5 0.6 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EMC98483.1 - 6.1e-11 42.7 3.1 2.8e-08 34.0 1.1 3.1 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily BcrAD_BadFG PF01869.20 EMC98483.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Lactamase_B_2 PF12706.7 EMC98483.1 - 0.068 12.7 0.3 0.36 10.3 0.3 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain zf-C3HC4_3 PF13920.6 EMC98484.1 - 3.9e-11 42.6 7.9 6.1e-11 42.0 7.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC98484.1 - 4.6e-10 39.3 2.9 8.5e-10 38.5 1.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EMC98484.1 - 4.1e-09 36.6 7.2 6.5e-09 36.0 7.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EMC98484.1 - 3.3e-08 33.3 8.5 5.1e-08 32.7 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC98484.1 - 9.8e-08 31.8 9.4 1.5e-07 31.2 9.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMC98484.1 - 1.2e-07 31.5 10.7 4e-06 26.5 12.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC98484.1 - 5.1e-07 29.4 4.1 1.1e-06 28.4 4.1 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EMC98484.1 - 0.00018 21.6 4.7 0.00058 20.0 5.0 1.7 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EMC98484.1 - 0.0012 19.1 5.1 0.0023 18.2 5.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EMC98484.1 - 0.0065 16.2 5.4 0.014 15.2 5.4 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 EMC98484.1 - 0.031 14.5 2.3 0.046 13.9 2.3 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 EMC98484.1 - 0.062 13.4 8.1 0.11 12.6 8.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.8 EMC98484.1 - 0.16 11.8 3.5 0.31 10.9 3.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 EMC98484.1 - 0.35 11.0 5.1 0.68 10.1 5.1 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 EMC98484.1 - 3.7 7.4 10.4 5 7.0 8.6 2.1 2 0 0 2 2 2 0 RING-like zinc finger DNApol_Exo PF18136.1 EMC98485.1 - 3.9e-104 347.8 0.0 7.5e-104 346.8 0.0 1.5 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EMC98485.1 - 6.3e-54 183.5 0.0 9.7e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A RTA1 PF04479.13 EMC98486.1 - 2.5e-66 223.2 4.8 3.6e-66 222.7 4.8 1.2 1 0 0 1 1 1 1 RTA1 like protein SnoaL_2 PF12680.7 EMC98487.1 - 7.6e-05 23.3 0.0 0.00011 22.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain HTH_7 PF02796.15 EMC98487.1 - 0.11 12.6 0.2 0.28 11.3 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DnaJ PF00226.31 EMC98488.1 - 2.8e-22 78.6 2.5 2.8e-22 78.6 2.5 2.2 2 0 0 2 2 2 1 DnaJ domain UBN_AB PF14075.6 EMC98488.1 - 1.7 8.3 9.3 4.8 6.8 3.7 2.4 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Inv-AAD PF18785.1 EMC98489.1 - 4.7e-54 181.7 0.2 5.3e-54 181.5 0.2 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EMC98489.1 - 3.5e-10 39.7 0.3 7.4e-10 38.6 0.3 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EMC98489.1 - 0.00099 19.0 0.2 0.0012 18.8 0.2 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Tryp_inh PF17983.1 EMC98489.1 - 4.2 7.5 7.4 3.7 7.7 0.7 2.4 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 ADH_zinc_N_2 PF13602.6 EMC98493.1 - 1.9e-29 103.4 0.0 3.3e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMC98493.1 - 4e-16 59.2 0.2 3.8e-15 56.0 0.0 2.5 3 1 1 4 4 4 1 Zinc-binding dehydrogenase Stn1 PF10451.9 EMC98495.1 - 9.7e-11 41.1 0.8 2.2e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EMC98495.1 - 0.0081 16.1 0.8 0.058 13.4 0.8 2.2 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Ank_4 PF13637.6 EMC98497.1 - 1.5e-08 35.0 0.0 6.1e-06 26.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMC98497.1 - 7e-07 29.7 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMC98497.1 - 0.0034 17.7 0.0 0.03 14.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EMC98497.1 - 0.059 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Methyltransf_23 PF13489.6 EMC98498.1 - 4.3e-20 72.2 0.0 5.9e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC98498.1 - 3.8e-19 69.1 0.0 6.5e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC98498.1 - 2.1e-15 57.2 0.0 4e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC98498.1 - 3.2e-14 53.5 0.0 5.2e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC98498.1 - 1.2e-13 51.1 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMC98498.1 - 3.3e-05 23.4 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EMC98498.1 - 0.00059 19.3 0.0 0.00081 18.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMC98498.1 - 0.0028 17.2 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EMC98498.1 - 0.0031 17.1 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 EMC98498.1 - 0.0084 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 EMC98498.1 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Peroxidase_2 PF01328.17 EMC98499.1 - 2.8e-51 174.7 0.0 3.9e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 FGGY_C PF02782.16 EMC98500.1 - 5.3e-74 248.2 1.3 1e-73 247.3 1.3 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EMC98500.1 - 1.9e-60 204.5 0.0 2.6e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EMC98500.1 - 0.12 11.9 0.3 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family ABC2_membrane_3 PF12698.7 EMC98502.1 - 0.42 9.7 3.2 0.61 9.1 3.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3357 PF11837.8 EMC98502.1 - 2.7 8.5 4.8 4.9 7.7 0.6 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) Sod_Fe_C PF02777.18 EMC98503.1 - 2.5e-36 123.9 0.1 4.6e-36 123.1 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMC98503.1 - 6.9e-31 106.6 0.4 1.1e-30 105.9 0.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain UCR_hinge PF02320.16 EMC98504.1 - 7.6e-26 90.1 12.7 1.2e-25 89.4 12.7 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein F-protein PF00469.20 EMC98504.1 - 0.057 13.0 2.1 0.05 13.2 0.9 1.5 1 1 0 1 1 1 0 Negative factor, (F-Protein) or Nef UPF0203 PF05254.12 EMC98504.1 - 0.062 13.5 5.3 0.11 12.8 5.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) HET PF06985.11 EMC98505.1 - 5.7e-30 104.6 0.0 9.5e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Drf_GBD PF06371.13 EMC98506.1 - 2.4e-15 56.6 0.1 1.5e-13 50.7 0.1 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain adh_short PF00106.25 EMC98507.1 - 2.6e-35 121.7 0.0 3.4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC98507.1 - 8.2e-24 84.5 0.0 1e-23 84.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC98507.1 - 0.0013 18.7 0.1 0.0024 17.8 0.1 1.5 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EMC98507.1 - 0.0087 16.0 0.0 0.026 14.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 EMC98507.1 - 0.063 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EMC98507.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 EMC98507.1 - 0.092 13.5 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 EMC98507.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RhoGAP PF00620.27 EMC98508.1 - 2.7e-22 79.2 0.0 3.4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF4538 PF15061.6 EMC98509.1 - 0.22 11.3 1.7 0.24 11.2 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4538) DUF4774 PF15999.5 EMC98510.1 - 0.032 14.1 1.9 0.078 12.8 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) Granulin PF00396.18 EMC98510.1 - 1.5 9.2 16.6 16 5.9 11.2 3.0 1 1 1 2 2 2 0 Granulin Methyltransf_16 PF10294.9 EMC98511.1 - 1.3e-17 64.1 0.0 6.6e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EMC98511.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_8 PF13523.6 EMC98513.1 - 1.3e-46 157.9 0.0 2.2e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4266 PF14086.6 EMC98513.1 - 0.41 11.6 1.7 0.87 10.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Aminotran_1_2 PF00155.21 EMC98514.1 - 2.1e-35 122.5 0.0 2.7e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Nuc_sug_transp PF04142.15 EMC98515.1 - 1.2e-100 336.8 14.9 1.5e-100 336.4 14.9 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EMC98515.1 - 6.1e-07 28.9 5.8 6.1e-07 28.9 5.8 2.1 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 EMC98515.1 - 4e-06 27.0 5.7 4e-06 27.0 5.7 2.6 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.6 EMC98515.1 - 0.0014 18.3 1.4 0.0014 18.3 1.4 2.4 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter TPT PF03151.16 EMC98515.1 - 0.029 13.7 17.1 0.42 9.9 7.9 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family DMT_6 PF04342.12 EMC98515.1 - 3.3 7.9 11.6 8.3 6.7 1.3 2.8 2 1 0 2 2 2 0 Putative member of DMT superfamily (DUF486) Tombus_P33 PF08500.10 EMC98516.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Tombusvirus p33 Sec63 PF02889.16 EMC98517.1 - 4e-33 114.7 0.0 6e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EMC98517.1 - 9.2e-23 80.9 0.0 1.9e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EMC98517.1 - 3.1e-11 43.6 0.0 6.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EMC98517.1 - 1.1e-07 32.1 0.0 3.9e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 EMC98517.1 - 2.6e-05 24.7 0.3 7.3e-05 23.3 0.3 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_19 PF13245.6 EMC98517.1 - 0.00017 21.9 0.0 0.0006 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMC98517.1 - 0.0065 16.7 0.1 0.033 14.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMC98517.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EMC98517.1 - 0.062 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 EMC98517.1 - 0.082 12.0 0.0 0.39 9.7 0.0 2.1 3 0 0 3 3 3 0 Type II/IV secretion system protein UQ_con PF00179.26 EMC98518.1 - 3e-19 69.1 0.1 8.1e-19 67.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Pex14_N PF04695.13 EMC98518.1 - 0.13 13.0 8.3 0.23 12.1 8.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Putative_PNPOx PF01243.20 EMC98520.1 - 3.1e-12 46.5 0.0 9.1e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EMC98520.1 - 0.068 13.2 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase SAP130_C PF16014.5 EMC98520.1 - 0.099 11.7 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Zn_clus PF00172.18 EMC98521.1 - 5.6e-05 23.2 8.3 0.00011 22.3 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_2 PF00328.22 EMC98522.1 - 6e-05 22.6 0.1 0.017 14.5 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Rtt106_N PF18215.1 EMC98524.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain PRP21_like_P PF12230.8 EMC98525.1 - 1.2e-48 165.8 5.8 3.5e-48 164.3 5.8 1.7 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EMC98525.1 - 5.7e-33 112.7 1.1 4.4e-16 58.6 0.4 2.5 2 0 0 2 2 2 2 Surp module RNF220 PF15926.5 EMC98525.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 PMT PF02366.18 EMC98526.1 - 3.7e-81 272.3 16.2 3.7e-81 272.3 16.2 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EMC98526.1 - 1.5e-65 220.5 12.6 1.5e-65 220.5 12.6 2.0 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EMC98526.1 - 6e-48 163.2 0.0 1e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 MIR domain DUF2530 PF10745.9 EMC98526.1 - 1.8 8.9 5.5 0.79 10.0 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) UCH PF00443.29 EMC98527.1 - 1e-43 149.7 0.0 1.5e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC98527.1 - 2.8e-08 33.7 0.0 6.2e-07 29.3 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pyr_redox_2 PF07992.14 EMC98528.1 - 4.2e-05 22.9 0.0 9.8e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC98528.1 - 0.0043 16.2 0.0 0.029 13.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EMC98528.1 - 0.024 13.9 0.2 0.85 8.8 0.1 2.9 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC98528.1 - 0.065 13.2 0.2 0.52 10.3 0.4 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Dioxygenase_C PF00775.21 EMC98531.1 - 3.4e-47 160.2 0.0 5.1e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EMC98531.1 - 1.3e-23 82.6 0.1 2.1e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EMC98531.1 - 0.00028 21.1 0.0 0.0015 18.8 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Pkinase_C PF00433.24 EMC98531.1 - 0.048 14.4 0.0 0.094 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain CDP-OH_P_transf PF01066.21 EMC98532.1 - 1.4e-16 61.0 0.1 1.4e-16 61.0 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.13 EMC98533.1 - 1.4e-40 137.7 0.7 2.3e-29 101.6 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP Exo_endo_phos PF03372.23 EMC98533.1 - 0.087 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FHA PF00498.26 EMC98536.1 - 8.2e-16 58.1 0.0 1.6e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EMC98536.1 - 0.00016 21.9 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Spc29 PF17082.5 EMC98536.1 - 0.075 12.9 6.2 0.024 14.5 1.8 2.2 1 1 0 2 2 2 0 Spindle Pole Component 29 Spectrin PF00435.21 EMC98536.1 - 0.1 13.1 5.4 2 8.9 4.7 2.6 1 1 0 1 1 1 0 Spectrin repeat Fez1 PF06818.15 EMC98536.1 - 1.7 9.0 15.7 0.74 10.2 11.9 2.2 2 0 0 2 2 2 0 Fez1 EMP24_GP25L PF01105.24 EMC98536.1 - 2.1 8.3 7.2 31 4.5 7.1 2.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sigma70_ner PF04546.13 EMC98536.1 - 2.4 8.0 13.3 0.27 11.1 8.6 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4140 PF13600.6 EMC98536.1 - 6.7 7.2 12.1 7.5 7.1 1.5 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) CN_hydrolase PF00795.22 EMC98538.1 - 8.8e-46 156.4 0.0 2.5e-45 154.8 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Asp_Glu_race PF01177.22 EMC98538.1 - 3.6e-10 40.1 0.1 7.6e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 EMC98538.1 - 0.0027 17.4 0.5 0.0044 16.7 0.5 1.3 1 0 0 1 1 1 1 Arylmalonate decarboxylase Fungal_trans PF04082.18 EMC98539.1 - 7.5e-22 77.6 0.0 1.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC98539.1 - 1.5e-05 25.0 9.2 1.5e-05 25.0 9.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 EMC98540.1 - 4.7e-102 342.0 35.2 5.6e-102 341.8 35.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cornichon PF03311.14 EMC98540.1 - 0.015 15.6 2.4 1.3 9.4 0.0 3.4 3 0 0 3 3 3 0 Cornichon protein NAD_binding_4 PF07993.12 EMC98541.1 - 6.9e-34 117.2 0.0 1.2e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EMC98541.1 - 1.8e-27 96.0 0.0 3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EMC98541.1 - 7.1e-09 35.5 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMC98541.1 - 7.9e-08 32.5 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PAP1 PF08601.10 EMC98543.1 - 1.1e-08 35.2 4.0 5.7e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 EMC98543.1 - 3.4e-07 30.3 11.3 6.1e-07 29.4 11.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 EMC98543.1 - 0.0085 15.8 4.3 0.012 15.4 4.3 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 EMC98543.1 - 0.055 14.0 10.8 0.087 13.4 10.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 EMC98543.1 - 0.13 12.4 11.7 0.2 11.8 10.6 1.8 1 1 1 2 2 2 0 Basic region leucine zipper Glutaredoxin2_C PF04399.13 EMC98543.1 - 0.21 11.5 0.9 0.36 10.7 0.9 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GvpL_GvpF PF06386.11 EMC98543.1 - 0.32 10.9 4.5 0.45 10.4 4.5 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ADIP PF11559.8 EMC98543.1 - 0.36 10.9 9.4 0.55 10.3 9.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 EMC98543.1 - 0.44 10.6 3.3 0.75 9.9 3.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Methyltrn_RNA_3 PF02598.17 EMC98544.1 - 6.5e-97 324.5 0.0 8.1e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Adaptin_N PF01602.20 EMC98545.1 - 1.7e-116 389.9 1.3 2.1e-116 389.6 1.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EMC98545.1 - 1.1e-55 187.9 0.3 2.7e-55 186.6 0.3 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EMC98545.1 - 4e-32 110.8 0.0 1.2e-31 109.2 0.0 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EMC98545.1 - 4.7e-20 71.8 1.3 1.8e-11 44.2 0.0 5.5 2 1 3 5 5 5 4 HEAT repeats Cnd1 PF12717.7 EMC98545.1 - 6.9e-11 42.4 8.4 0.00071 19.7 0.0 5.0 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EMC98545.1 - 0.00017 21.9 0.9 15 6.6 0.0 5.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat HEAT PF02985.22 EMC98545.1 - 0.002 18.3 9.4 0.29 11.5 0.1 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EMC98545.1 - 0.028 15.0 0.3 0.028 15.0 0.3 3.3 3 1 0 3 3 3 0 HEAT-like repeat DUF4765 PF15962.5 EMC98545.1 - 0.099 10.6 0.2 0.16 9.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4765) NPA PF16469.5 EMC98545.1 - 0.15 12.6 0.0 0.42 11.2 0.0 1.8 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 RTP1_C1 PF10363.9 EMC98545.1 - 0.19 11.9 0.8 5.9 7.1 0.0 3.5 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 AA_permease_2 PF13520.6 EMC98546.1 - 2.7e-42 145.1 50.2 3.4e-42 144.8 50.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC98546.1 - 6.9e-18 64.5 40.1 1.1e-17 63.8 40.1 1.3 1 0 0 1 1 1 1 Amino acid permease Cupin_2 PF07883.11 EMC98547.1 - 6.7e-07 28.9 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EMC98547.1 - 0.0035 17.0 0.1 0.0099 15.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF861) CAP59_mtransfer PF11735.8 EMC98548.1 - 1e-82 277.5 0.0 1.4e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MBA1 PF07961.11 EMC98549.1 - 2.2e-11 43.3 0.0 7.2e-10 38.3 0.0 2.1 2 0 0 2 2 2 2 MBA1-like protein BBIP10 PF14777.6 EMC98549.1 - 0.12 11.9 2.8 0.24 11.0 0.7 2.3 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 SUI1 PF01253.22 EMC98550.1 - 4.6e-28 97.6 4.0 6.5e-28 97.1 4.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 EMC98550.1 - 0.07 13.4 0.2 0.11 12.8 0.2 1.2 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain Med12 PF09497.10 EMC98551.1 - 3.9e-27 94.3 0.3 9.7e-27 93.1 0.3 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DUF1138 PF06592.13 EMC98551.1 - 0.0056 16.7 0.5 0.23 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1138) TEA PF01285.18 EMC98552.1 - 0.056 13.5 0.0 1.2 9.3 0.0 2.0 1 1 0 1 1 1 0 TEA/ATTS domain LIAS_N PF16881.5 EMC98553.1 - 4.1e-21 75.4 0.4 2.5e-20 72.9 0.4 2.1 1 1 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EMC98553.1 - 1.5e-13 51.4 0.0 3.2e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Sec2p PF06428.11 EMC98555.1 - 7.9e-28 96.3 14.8 7.9e-28 96.3 14.8 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p CENP-Q PF13094.6 EMC98555.1 - 0.0038 17.4 4.2 0.0038 17.4 4.2 3.3 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Tup_N PF08581.10 EMC98555.1 - 0.035 14.4 10.8 0.16 12.3 1.3 2.6 2 1 0 2 2 2 0 Tup N-terminal CTNNB1_binding PF08347.11 EMC98555.1 - 0.065 13.4 0.8 0.14 12.3 0.8 1.5 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Uso1_p115_C PF04871.13 EMC98555.1 - 0.093 13.1 19.7 2.5 8.5 0.4 3.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 PF09787.9 EMC98555.1 - 0.18 11.2 18.9 0.3 10.5 18.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Baculo_F PF12259.8 EMC98555.1 - 1.1 7.6 6.1 1.6 7.1 6.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein DUF3584 PF12128.8 EMC98555.1 - 1.7 6.1 21.0 2.8 5.3 21.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SKA1 PF07160.12 EMC98555.1 - 1.9 8.3 13.2 1.7 8.5 2.7 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Spc7 PF08317.11 EMC98555.1 - 6.2 5.6 25.1 5.5 5.8 1.2 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein GCN5L1 PF06320.13 EMC98555.1 - 6.8 6.9 14.2 0.71 10.0 8.3 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Fib_alpha PF08702.10 EMC98555.1 - 8 6.6 11.5 9.4 6.4 6.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAD_binding_7 PF03441.14 EMC98556.1 - 2.7e-56 190.3 1.8 5.4e-56 189.3 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EMC98556.1 - 3.1e-38 131.4 0.0 6.4e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase TF_AP-2 PF03299.14 EMC98556.1 - 0.077 13.0 0.5 0.6 10.0 0.2 2.3 2 0 0 2 2 2 0 Transcription factor AP-2 HAD PF12710.7 EMC98557.1 - 8.2e-22 78.5 0.0 1.1e-21 78.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMC98557.1 - 8.1e-16 58.9 0.2 1.4e-15 58.1 0.2 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EMC98557.1 - 2.4e-09 37.3 0.1 1.7e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EMC98557.1 - 0.00019 21.5 0.2 0.23 11.5 0.1 3.2 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EMC98557.1 - 0.0032 16.9 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase CIA30 PF08547.12 EMC98558.1 - 2.2e-39 135.1 0.0 2.7e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 EMC98558.1 - 0.022 14.7 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain Mito_carr PF00153.27 EMC98559.1 - 2.2e-67 223.0 1.4 1.6e-22 79.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MRP-L27 PF09809.9 EMC98560.1 - 1.4e-19 70.0 0.1 1.7e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.13 EMC98561.1 - 4.9e-179 597.5 58.4 4.9e-179 597.5 58.4 2.1 1 1 1 2 2 2 1 Utp14 protein Plasmid_parti PF01672.16 EMC98563.1 - 0.014 16.0 1.4 0.016 15.8 1.4 1.3 1 0 0 1 1 1 0 Putative plasmid partition protein RVT_1 PF00078.27 EMC98563.1 - 0.056 12.9 1.5 0.088 12.3 0.7 1.6 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) LSM PF01423.22 EMC98564.1 - 2.2e-17 62.5 0.6 2.8e-17 62.1 0.6 1.1 1 0 0 1 1 1 1 LSM domain Tail_tube PF10618.9 EMC98564.1 - 0.027 14.4 0.0 0.039 13.9 0.0 1.4 1 1 0 1 1 1 0 Phage tail tube protein SM-ATX PF14438.6 EMC98564.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF1713 PF08213.11 EMC98565.1 - 6.3e-08 32.4 16.9 1.9e-07 30.8 16.9 1.9 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Exonuc_VII_L PF02601.15 EMC98565.1 - 0.6 9.6 7.6 0.086 12.4 3.2 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit AhpC-TSA_2 PF13911.6 EMC98566.1 - 5.4e-20 71.6 0.0 8.8e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme SabA_adhesion PF18304.1 EMC98566.1 - 0.0018 17.6 0.1 0.0028 17.0 0.1 1.2 1 0 0 1 1 1 1 SabA N-terminal extracellular adhesion domain AhpC-TSA PF00578.21 EMC98566.1 - 0.0062 16.5 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMC98566.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin tRNA-synt_2 PF00152.20 EMC98567.1 - 2e-59 201.2 0.0 2.8e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMC98567.1 - 7.7e-11 41.8 0.0 1.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMC98567.1 - 0.0024 17.4 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) IGPS PF00218.21 EMC98568.1 - 1.9e-95 318.8 0.0 5e-95 317.5 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EMC98568.1 - 3.7e-51 173.7 0.2 2.1e-46 158.2 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EMC98568.1 - 3.8e-44 150.7 0.0 7e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NanE PF04131.14 EMC98568.1 - 4.5e-05 22.7 0.9 0.0037 16.5 0.2 2.3 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.19 EMC98568.1 - 0.0035 17.1 1.8 0.14 11.9 0.3 3.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain Peptidase_C26 PF07722.13 EMC98568.1 - 0.0037 17.0 0.5 0.0037 17.0 0.5 2.8 3 1 0 3 3 3 1 Peptidase C26 His_biosynth PF00977.21 EMC98568.1 - 0.086 12.3 0.7 0.73 9.2 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein BRCT PF00533.26 EMC98569.1 - 4.8e-05 23.7 0.2 0.00017 21.9 0.2 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EMC98569.1 - 0.00014 21.7 0.2 0.00068 19.5 0.2 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 EMC98569.1 - 0.00026 21.3 0.4 0.00074 19.9 0.1 1.9 1 1 1 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EMC98569.1 - 0.023 15.0 0.4 0.064 13.6 0.4 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain RR_TM4-6 PF06459.12 EMC98569.1 - 0.4 10.5 13.6 0.59 9.9 13.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WGR PF05406.15 EMC98569.1 - 0.57 10.3 0.0 0.57 10.3 0.0 3.5 4 0 0 4 4 4 0 WGR domain Fmp27_SW PF10305.9 EMC98569.1 - 0.85 10.4 8.7 4.6 8.0 0.6 2.8 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain RXLR PF16810.5 EMC98569.1 - 4.4 7.7 18.9 0.51 10.8 6.9 2.5 2 1 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity NDUF_B7 PF05676.13 EMC98570.1 - 8.7e-31 105.5 4.6 1e-30 105.2 4.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EMC98570.1 - 0.0071 16.3 0.8 0.011 15.7 0.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_4 PF13637.6 EMC98571.1 - 2.2e-10 40.8 0.1 0.0004 20.9 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMC98571.1 - 1.4e-09 38.4 0.0 0.0015 19.1 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EMC98571.1 - 1.5e-07 31.6 0.0 0.027 14.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EMC98571.1 - 1.5e-06 28.4 0.1 0.051 13.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC98571.1 - 3.3e-06 27.0 0.1 0.67 10.7 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.13 EMC98571.1 - 4.7e-05 23.2 0.2 0.00025 20.9 0.2 2.1 1 1 0 1 1 1 1 KilA-N domain SSB PF00436.25 EMC98571.1 - 0.13 12.3 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 Single-strand binding protein family RICTOR_M PF14666.6 EMC98571.1 - 0.23 11.2 0.8 23 4.8 0.0 3.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain Clr5 PF14420.6 EMC98573.1 - 2.9e-10 40.2 0.2 1.4e-09 38.0 0.1 2.3 2 0 0 2 2 2 1 Clr5 domain Fungal_trans PF04082.18 EMC98574.1 - 8.5e-14 51.2 0.0 1.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC98574.1 - 7.4e-10 38.8 7.6 1.2e-09 38.1 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_3 PF13640.6 EMC98575.1 - 6e-09 36.7 0.3 2e-08 35.0 0.3 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATG2_CAD PF13329.6 EMC98576.1 - 2e-36 125.1 0.0 3.4e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EMC98576.1 - 6.4e-25 87.3 1.7 2.6e-24 85.4 0.1 2.7 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EMC98576.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal zf-MIZ PF02891.20 EMC98577.1 - 1.5e-08 34.3 0.1 3.2e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SH3_9 PF14604.6 EMC98578.1 - 4.5e-14 52.0 0.0 1.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMC98578.1 - 1.2e-11 44.0 0.0 2.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 EMC98578.1 - 5.7e-11 42.9 0.0 6.1e-10 39.6 0.0 2.5 1 1 0 1 1 1 1 PH domain SAM_2 PF07647.17 EMC98578.1 - 1.2e-08 35.0 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 EMC98578.1 - 2.8e-05 23.7 0.0 6.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 EMC98578.1 - 0.0086 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 EMC98578.1 - 0.059 13.7 0.0 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain GCIP PF13324.6 EMC98579.1 - 0.0018 17.9 2.9 0.65 9.6 0.0 2.5 2 1 0 2 2 2 2 Grap2 and cyclin-D-interacting DUF1878 PF08963.10 EMC98579.1 - 0.22 12.1 0.3 3.8 8.0 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1878) Helo_like_N PF17111.5 EMC98579.1 - 0.51 9.7 3.8 4.6 6.6 0.0 2.9 2 1 0 3 3 3 0 Fungal N-terminal domain of STAND proteins Fer4_13 PF13370.6 EMC98579.1 - 1.4 9.5 7.3 2.4 8.8 0.3 4.1 3 2 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Aldo_ket_red PF00248.21 EMC98581.1 - 3.1e-44 151.4 0.0 3.8e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sec61_beta PF03911.16 EMC98582.1 - 1.2e-17 63.7 1.3 2.2e-17 62.8 1.3 1.5 1 0 0 1 1 1 1 Sec61beta family CALM_bind PF16025.5 EMC98582.1 - 2.4 8.7 6.4 6 7.4 6.4 1.7 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Aa_trans PF01490.18 EMC98585.1 - 1.5e-42 145.8 33.6 1.7e-42 145.6 33.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bap31 PF05529.12 EMC98585.1 - 0.25 11.2 3.9 0.16 11.8 0.8 2.3 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region Phage_holin_3_7 PF05449.11 EMC98586.1 - 0.11 12.5 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 Anp1 PF03452.14 EMC98587.1 - 1e-108 362.8 0.0 1.2e-108 362.6 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EMC98587.1 - 0.0035 17.2 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 DSX_dimer PF08828.10 EMC98587.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Doublesex dimerisation domain Tom37 PF10568.9 EMC98587.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein zf-C2H2 PF00096.26 EMC98589.1 - 0.0038 17.6 17.7 0.044 14.3 9.7 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC98589.1 - 0.065 14.1 9.6 0.065 14.1 9.6 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.11 EMC98589.1 - 8.8 6.3 10.6 2.5 8.1 5.6 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 EMC98589.1 - 9.5 6.6 16.9 31 5.0 0.2 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF3776 PF12618.8 EMC98594.1 - 0.012 16.1 0.2 0.032 14.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) HAD_2 PF13419.6 EMC98595.1 - 6.6e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC98595.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DLH PF01738.18 EMC98596.1 - 3.2e-12 46.5 0.5 4.9e-12 45.9 0.5 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family GAF_2 PF13185.6 EMC98597.1 - 1.1e-12 48.5 0.0 1.6e-12 47.9 0.0 1.5 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 EMC98597.1 - 1.6e-08 35.2 0.1 2.2e-08 34.8 0.1 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EMC98597.1 - 0.00028 21.2 0.0 0.00047 20.5 0.0 1.5 1 1 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 EMC98597.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor Aldo_ket_red PF00248.21 EMC98598.1 - 5.2e-50 170.3 0.0 5.9e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 EMC98599.1 - 1.6e-40 139.1 12.2 1.6e-40 139.1 12.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98599.1 - 1.2e-11 44.2 9.2 1.2e-11 44.2 9.2 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMC98599.1 - 5.8e-06 25.0 4.2 1.1e-05 24.1 4.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2269 PF10027.9 EMC98599.1 - 0.006 16.7 6.4 0.45 10.6 0.3 3.1 3 0 0 3 3 3 2 Predicted integral membrane protein (DUF2269) Zip PF02535.22 EMC98599.1 - 0.016 14.5 1.4 0.16 11.2 0.2 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter CPP1-like PF11833.8 EMC98599.1 - 0.051 13.2 0.4 1 9.0 0.5 2.7 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like EMP70 PF02990.16 EMC98599.1 - 0.92 8.1 4.6 8.3 5.0 0.4 2.3 2 0 0 2 2 2 0 Endomembrane protein 70 DUF4231 PF14015.6 EMC98599.1 - 6.7 7.2 6.0 0.77 10.2 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) LigB PF02900.18 EMC98600.1 - 7.9e-15 54.7 0.0 9.8e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.18 EMC98601.1 - 3.7e-10 39.3 0.8 6.6e-10 38.5 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EMC98601.1 - 8.6e-08 32.2 7.3 0.00022 21.5 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC98601.1 - 2e-07 31.1 2.7 2e-07 31.1 2.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.18 EMC98601.1 - 7.2e-05 22.8 11.3 7.2e-05 22.8 11.3 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EMC98601.1 - 0.00041 20.9 13.1 0.032 15.1 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger BolA PF01722.18 EMC98601.1 - 0.13 12.6 0.3 7.2 7.0 0.3 2.6 1 1 0 1 1 1 0 BolA-like protein zf-met PF12874.7 EMC98601.1 - 0.2 12.1 1.4 6.7 7.2 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EMC98601.1 - 0.35 10.9 8.3 0.49 10.5 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PepX_C PF08530.10 EMC98602.1 - 2.6e-40 138.7 0.0 4e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EMC98602.1 - 1.6e-37 129.6 0.8 2.4e-37 129.0 0.8 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EMC98602.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 adh_short_C2 PF13561.6 EMC98603.1 - 1.9e-40 138.9 1.6 6.9e-40 137.1 1.6 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC98603.1 - 2.7e-38 131.4 0.0 7.2e-38 130.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC98603.1 - 7.3e-09 35.8 0.1 1.3e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC98603.1 - 0.051 13.0 0.1 0.4 10.1 0.1 2.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cupin_2 PF07883.11 EMC98604.1 - 2e-08 33.8 0.0 2.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EMC98604.1 - 0.041 13.6 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Histidinol_dh PF00815.20 EMC98605.1 - 4.5e-138 460.7 0.4 5.6e-138 460.4 0.4 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase AAA_24 PF13479.6 EMC98605.1 - 0.051 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.19 EMC98606.1 - 1.1e-21 77.5 0.1 5.9e-21 75.1 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.11 EMC98606.1 - 4.2e-10 39.6 0.1 1.2e-09 38.1 0.1 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 EMC98606.1 - 6e-06 25.7 2.2 3.2e-05 23.3 2.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC98606.1 - 7.6e-06 26.1 0.3 1.9e-05 24.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMC98606.1 - 0.00039 19.6 1.3 0.00073 18.7 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC98606.1 - 0.00054 19.6 3.0 0.01 15.5 3.8 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC98606.1 - 0.0037 16.0 0.5 0.021 13.5 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EMC98606.1 - 0.013 14.8 0.1 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EMC98606.1 - 0.031 13.2 1.4 0.19 10.5 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 EMC98606.1 - 0.05 13.0 0.4 0.089 12.1 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase VWA_3_C PF18571.1 EMC98606.1 - 0.096 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain GIDA PF01134.22 EMC98606.1 - 0.1 11.7 0.8 0.17 10.9 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EMC98606.1 - 0.11 11.8 0.2 0.3 10.4 0.2 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain EamA PF00892.20 EMC98607.1 - 7.1e-08 32.7 26.5 8.1e-07 29.3 2.6 2.7 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 EMC98607.1 - 9.3e-06 24.8 2.4 1.9e-05 23.8 2.4 1.5 1 1 0 1 1 1 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 EMC98607.1 - 0.0068 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF202 PF02656.15 EMC98609.1 - 6.2e-22 77.8 0.2 6.2e-22 77.8 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ELL PF10390.9 EMC98612.1 - 0.00063 19.3 0.1 0.00063 19.3 0.1 2.6 3 1 0 3 3 3 1 RNA polymerase II elongation factor ELL 2-Hacid_dh_C PF02826.19 EMC98613.1 - 1e-42 145.5 0.0 1.7e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMC98613.1 - 1.1e-10 41.2 0.0 4e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Gal11_ABD1 PF18535.1 EMC98613.1 - 0.16 12.1 0.2 1 9.5 0.1 2.2 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) Acetyltransf_7 PF13508.7 EMC98614.1 - 0.00074 19.9 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMC98614.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC98614.1 - 0.056 13.7 0.0 0.068 13.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family ApbA PF02558.16 EMC98615.1 - 6.2e-31 107.1 0.0 1.1e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EMC98615.1 - 1.8e-29 102.5 0.0 2.9e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Arr-ms PF12120.8 EMC98615.1 - 0.09 13.0 0.0 0.62 10.3 0.0 2.3 2 1 1 3 3 3 0 Rifampin ADP-ribosyl transferase AAL_decarboxy PF03306.13 EMC98616.1 - 7.2e-33 113.8 0.0 1e-18 67.5 0.0 2.2 1 1 1 2 2 2 2 Alpha-acetolactate decarboxylase Pkinase PF00069.25 EMC98617.1 - 1.2e-14 54.4 0.0 2.6e-14 53.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC98617.1 - 1.1e-08 34.7 0.0 4.6e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase zf-NOSIP PF15906.5 EMC98618.1 - 1.5e-07 31.5 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 EMC98618.1 - 5e-07 29.5 18.2 4.1e-05 23.4 4.9 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC98618.1 - 4.2e-06 27.0 16.3 0.0028 18.0 5.7 3.5 3 1 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 EMC98618.1 - 6.9e-06 26.0 13.6 0.0026 17.7 2.1 3.2 3 0 0 3 3 3 2 RING-type zinc-finger FYVE PF01363.21 EMC98618.1 - 2.2e-05 24.5 8.6 3.2e-05 24.0 2.8 2.5 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_5 PF14634.6 EMC98618.1 - 0.00012 21.9 16.9 0.00026 20.9 6.6 2.8 2 1 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.12 EMC98618.1 - 0.00023 20.6 3.3 0.021 14.2 1.8 2.4 2 0 0 2 2 2 2 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 EMC98618.1 - 0.00025 20.8 18.1 0.0059 16.4 1.7 3.4 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC98618.1 - 0.008 16.0 19.4 0.06 13.2 6.1 3.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC98618.1 - 0.022 14.6 20.7 0.53 10.2 9.6 3.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 FYDLN_acid PF09538.10 EMC98618.1 - 0.089 13.5 0.2 0.089 13.5 0.2 3.2 2 1 0 2 2 1 0 Protein of unknown function (FYDLN_acid) IBR PF01485.21 EMC98618.1 - 0.44 10.8 13.4 5.1 7.4 0.4 3.1 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 EMC98618.1 - 1.7 8.9 16.4 2.8 8.2 6.7 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 EMC98618.1 - 5.6 7.0 15.1 0.39 10.7 2.2 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Casc1_N PF15927.5 EMC98618.1 - 7.5 6.2 9.3 13 5.4 9.3 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Acyltransferase PF01553.21 EMC98619.1 - 4.1e-15 55.6 0.0 1e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase UDG PF03167.19 EMC98621.1 - 2.7e-19 69.7 0.1 7e-19 68.3 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily CMV_US PF08001.11 EMC98621.1 - 0.69 9.1 2.1 17 4.6 0.2 2.1 2 0 0 2 2 2 0 CMV US ICMT PF04140.14 EMC98622.1 - 3.6e-27 94.6 0.1 8.1e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EMC98622.1 - 5.2e-11 42.9 0.3 5.2e-11 42.9 0.3 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EMC98622.1 - 1.3e-06 28.1 0.5 2.4e-06 27.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 EMC98622.1 - 0.00082 18.2 0.9 0.0014 17.5 0.9 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PH_10 PF15411.6 EMC98625.1 - 1.9e-29 102.4 0.2 4e-29 101.4 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EMC98625.1 - 1.3e-13 51.6 0.0 2.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EMC98625.1 - 2.7e-11 43.7 0.0 9.8e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 EMC98625.1 - 0.00026 21.2 4.8 0.00048 20.4 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EMC98625.1 - 0.00043 20.2 5.1 0.00075 19.4 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EMC98625.1 - 0.0019 18.5 2.5 0.0044 17.3 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EMC98625.1 - 0.002 17.7 1.7 0.002 17.7 1.7 1.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EMC98625.1 - 0.0066 16.3 5.2 0.012 15.4 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EMC98625.1 - 0.026 14.8 4.3 0.049 13.9 4.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 EMC98625.1 - 0.028 14.3 1.9 0.057 13.3 1.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC98625.1 - 0.057 13.3 4.6 0.11 12.4 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 EMC98625.1 - 0.083 13.4 0.1 0.21 12.1 0.1 1.7 1 0 0 1 1 1 0 PH domain DUF1147 PF06615.11 EMC98625.1 - 0.16 12.0 0.2 0.39 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING_11 PF17123.5 EMC98625.1 - 0.37 10.6 2.6 0.72 9.6 2.6 1.5 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 EMC98625.1 - 0.44 10.4 2.9 0.81 9.6 2.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-HYPF PF07503.12 EMC98627.1 - 0.026 14.3 0.2 0.026 14.3 0.2 2.2 2 0 0 2 2 2 0 HypF finger CPDase PF07823.11 EMC98628.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Prominin PF05478.11 EMC98628.1 - 0.046 11.7 0.2 0.067 11.1 0.2 1.2 1 0 0 1 1 1 0 Prominin HEAT PF02985.22 EMC98628.1 - 0.098 13.0 0.4 1.7 9.1 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat DUF1981 PF09324.10 EMC98628.1 - 0.53 10.2 1.8 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) DCB PF16213.5 EMC98628.1 - 2.1 8.0 9.9 8.8 6.0 0.8 3.5 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 SCA7 PF08313.12 EMC98629.1 - 8.4e-31 105.7 1.3 8.4e-31 105.7 1.3 1.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.11 EMC98629.1 - 0.0014 18.2 0.7 0.0025 17.4 0.7 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) RNF220 PF15926.5 EMC98629.1 - 0.013 15.1 0.1 0.013 15.1 0.1 1.5 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 MAPEG PF01124.18 EMC98631.1 - 6.2e-22 77.9 1.4 7.6e-22 77.6 1.4 1.1 1 0 0 1 1 1 1 MAPEG family Lectin_leg-like PF03388.13 EMC98632.1 - 4.2e-71 238.9 0.1 5.3e-71 238.6 0.1 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 EMC98632.1 - 4.8e-07 29.6 0.0 2.4e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Legume lectin domain ATG27 PF09451.10 EMC98632.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 ThiF PF00899.21 EMC98633.1 - 1.7e-38 132.4 0.0 2.5e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 EMC98633.1 - 0.029 14.6 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EMC98633.1 - 0.053 13.8 0.9 0.3 11.3 0.9 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CagA PF03507.13 EMC98633.1 - 0.086 12.8 0.0 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 CagA exotoxin Epimerase PF01370.21 EMC98635.1 - 2.5e-05 23.9 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC98635.1 - 0.16 11.3 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ecl1 PF12855.7 EMC98637.1 - 7e-27 95.7 13.9 7e-27 95.7 13.9 1.8 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 EMC98637.1 - 0.00085 19.4 0.6 0.0014 18.7 0.6 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EMC98637.1 - 0.044 14.1 0.8 0.069 13.5 0.8 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding YacG PF03884.14 EMC98637.1 - 0.049 13.4 0.8 0.11 12.2 0.8 1.5 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG zf-FLZ PF04570.14 EMC98637.1 - 0.066 12.7 2.2 0.38 10.3 2.2 2.0 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 EMC98637.1 - 0.86 9.8 4.3 0.76 9.9 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) ADH_N PF08240.12 EMC98640.1 - 2.4e-27 95.0 1.2 5.3e-27 93.8 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC98640.1 - 1.5e-10 41.2 0.1 2.1e-07 31.0 0.0 2.4 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EMC98640.1 - 0.0047 16.8 2.8 0.0047 16.8 2.8 2.7 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated ABC_membrane_2 PF06472.15 EMC98642.1 - 2.7e-88 295.9 0.1 4.5e-88 295.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EMC98642.1 - 8.8e-17 61.9 0.0 1.5e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EMC98642.1 - 0.008 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EMC98642.1 - 0.027 14.2 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EMC98642.1 - 0.09 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EMC98642.1 - 0.2 12.1 0.0 0.48 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain GWT1 PF06423.12 EMC98643.1 - 4.7e-41 140.4 0.0 1.1e-40 139.2 0.0 1.6 1 0 0 1 1 1 1 GWT1 Exc PF07825.11 EMC98644.1 - 0.0058 16.6 0.1 0.0082 16.1 0.1 1.3 1 0 0 1 1 1 1 Excisionase-like protein SET PF00856.28 EMC98646.1 - 3e-12 47.3 0.1 3.4e-11 43.8 0.1 2.2 1 1 0 1 1 1 1 SET domain MMM1 PF10296.9 EMC98648.1 - 1.4e-06 27.6 0.0 4.7e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 SPX PF03105.19 EMC98648.1 - 0.028 14.3 1.1 0.032 14.2 1.1 1.2 1 0 0 1 1 1 0 SPX domain S36_mt PF10937.8 EMC98651.1 - 0.019 16.5 0.6 0.022 16.4 0.6 1.2 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial Catalase PF00199.19 EMC98652.1 - 8.4e-172 571.5 2.4 1.2e-171 571.1 2.4 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EMC98652.1 - 5.8e-20 71.3 0.0 1.7e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EMC98652.1 - 9.2e-11 41.6 0.2 7e-10 38.7 0.1 2.5 3 1 0 3 3 3 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EMC98652.1 - 3.4e-08 33.5 0.0 6.6e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family Nas2_N PF18265.1 EMC98653.1 - 2e-28 98.1 0.0 3.3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EMC98653.1 - 2.2e-12 46.6 0.1 3.6e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EMC98653.1 - 1.8e-07 31.4 0.0 3.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EMC98653.1 - 2.1e-06 28.1 0.0 3.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 EMC98653.1 - 2.4e-05 24.6 0.0 4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 EMC98654.1 - 9.8e-50 168.3 0.0 1.2e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC98654.1 - 4e-30 104.5 0.1 1.1e-29 103.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC98654.1 - 4.2e-11 42.6 0.0 5.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMC98654.1 - 7.3e-05 22.2 0.0 9.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMC98654.1 - 0.0002 21.4 0.0 0.00037 20.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EMC98654.1 - 0.00057 20.2 0.1 0.0043 17.4 0.1 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.20 EMC98654.1 - 0.007 15.6 1.7 0.74 8.9 0.1 2.7 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.12 EMC98654.1 - 0.027 13.9 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 EMC98654.1 - 0.031 14.2 0.1 9.1 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EMC98654.1 - 0.042 13.4 0.1 0.07 12.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EMC98654.1 - 0.055 13.2 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EMC98654.1 - 0.075 13.0 0.1 0.17 11.9 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DAP3 PF10236.9 EMC98654.1 - 0.078 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.10 EMC98654.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EMC98654.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EMC98654.1 - 0.15 11.3 0.4 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_33 PF13671.6 EMC98654.1 - 0.17 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain ubiquitin PF00240.23 EMC98655.1 - 7.7e-22 76.8 0.2 2e-21 75.5 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EMC98655.1 - 5.6e-11 42.1 0.0 1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EMC98655.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain tify PF06200.14 EMC98655.1 - 0.14 11.5 0.2 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 tify domain Aldedh PF00171.22 EMC98656.1 - 1.6e-141 472.0 0.0 2e-141 471.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SSF PF00474.17 EMC98658.1 - 4.2e-17 62.1 28.3 6.7e-17 61.5 28.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family CoA_binding_3 PF13727.6 EMC98658.1 - 0.018 15.0 0.7 0.088 12.8 0.7 2.2 1 0 0 1 1 1 0 CoA-binding domain ADH_N PF08240.12 EMC98659.1 - 3.7e-34 116.9 1.8 4.2e-34 116.7 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC98659.1 - 2.9e-25 88.8 0.7 4.5e-25 88.1 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMC98659.1 - 1.4e-09 37.8 0.2 2.2e-09 37.1 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMC98659.1 - 2e-05 25.6 0.0 3.7e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMC98659.1 - 3.2e-05 23.3 0.6 4.8e-05 22.8 0.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EMC98659.1 - 0.0039 16.8 0.1 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 EMC98659.1 - 0.0071 15.6 0.7 0.014 14.6 0.3 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MTS PF05175.14 EMC98659.1 - 0.013 15.0 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EMC98659.1 - 0.025 14.3 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Pyr_redox_3 PF13738.6 EMC98659.1 - 0.026 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMC98659.1 - 0.05 12.3 0.2 0.073 11.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_25 PF13649.6 EMC98659.1 - 0.07 13.8 0.1 0.15 12.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 EMC98659.1 - 0.09 12.8 0.2 0.25 11.4 0.2 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 EMC98659.1 - 0.11 12.9 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain DUF1996 PF09362.10 EMC98661.1 - 5.6e-82 275.3 2.0 7.8e-82 274.8 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EMC98661.1 - 3.5e-19 68.8 11.4 1.1e-18 67.2 11.4 1.9 1 0 0 1 1 1 1 WSC domain TrpP PF17099.5 EMC98664.1 - 0.035 13.9 0.4 0.052 13.3 0.4 1.1 1 0 0 1 1 1 0 Tryptophan transporter TrpP DUF2304 PF10066.9 EMC98664.1 - 0.064 13.5 1.7 0.11 12.7 1.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF2207 PF09972.9 EMC98664.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM61 PF15105.6 EMC98664.1 - 0.31 10.9 1.9 3.9 7.2 0.2 2.6 2 0 0 2 2 2 0 TMEM61 protein family SelP_N PF04592.14 EMC98664.1 - 5.5 6.3 9.2 10 5.5 9.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cmc1 PF08583.10 EMC98665.1 - 2.3e-11 43.6 17.6 8.3e-11 41.8 17.7 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EMC98665.1 - 0.051 13.6 5.3 0.097 12.7 5.3 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EMC98665.1 - 0.29 11.3 8.5 1.7 8.9 8.4 2.1 1 1 0 1 1 1 0 CHCH domain DUF3128 PF11326.8 EMC98665.1 - 4.1 7.8 20.1 3.9e+02 1.5 20.1 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) WD40 PF00400.32 EMC98666.1 - 8.7e-40 134.0 16.5 1.2e-05 26.0 0.0 7.5 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC98666.1 - 6.8e-11 42.3 0.3 0.00054 20.2 0.1 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 EMC98666.1 - 0.00036 20.4 1.7 0.035 13.9 0.1 2.2 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 EMC98666.1 - 0.0048 15.9 0.6 3.8 6.4 0.0 4.2 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EMC98666.1 - 0.017 13.7 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nup160 PF11715.8 EMC98666.1 - 0.12 11.0 1.2 12 4.3 0.1 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 TRAPP PF04051.16 EMC98667.1 - 2.6e-30 105.1 0.0 3.1e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zinc_ribbon_2 PF13240.6 EMC98670.1 - 0.07 12.9 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain FRG1 PF06229.12 EMC98673.1 - 6.6e-46 156.4 4.0 9.2e-46 156.0 4.0 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EMC98673.1 - 0.091 13.0 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Fascin domain Pyr_redox_2 PF07992.14 EMC98674.1 - 2.7e-48 164.7 0.8 3.6e-48 164.3 0.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EMC98674.1 - 8.7e-16 57.6 0.0 2.7e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EMC98674.1 - 1e-14 54.9 2.1 6.3e-14 52.3 0.9 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EMC98674.1 - 6.1e-06 26.1 0.0 3.6e-05 23.6 0.0 2.3 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain Trp_halogenase PF04820.14 EMC98674.1 - 6.7e-05 21.9 0.3 0.00015 20.8 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Reductase_C PF14759.6 EMC98674.1 - 0.00056 20.4 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal UDPG_MGDP_dh_N PF03721.14 EMC98674.1 - 0.066 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EMC98674.1 - 0.086 12.7 0.4 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sel1 PF08238.12 EMC98675.1 - 2e-41 139.5 33.1 2.6e-05 24.7 0.3 12.3 12 0 0 12 12 12 10 Sel1 repeat TPR_7 PF13176.6 EMC98675.1 - 0.0051 16.7 11.5 1.6 8.9 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMC98675.1 - 0.013 16.2 21.5 9.7 6.9 0.0 7.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMC98675.1 - 0.04 13.7 0.0 0.04 13.7 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMC98675.1 - 0.058 13.3 5.0 0.34 10.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SARAF PF06682.12 EMC98675.1 - 0.13 11.9 2.4 0.28 10.8 0.0 2.5 2 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis TPR_2 PF07719.17 EMC98675.1 - 0.77 10.0 0.0 0.77 10.0 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 EMC98675.1 - 1.1 9.8 4.4 1.8 9.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EMC98675.1 - 1.2 9.6 0.0 1.2 9.6 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat HemY_N PF07219.13 EMC98675.1 - 3.4 7.9 6.2 3 8.1 0.1 3.6 3 0 0 3 3 3 0 HemY protein N-terminus F-box-like PF12937.7 EMC98676.1 - 3.8e-07 29.9 0.2 6.4e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC98676.1 - 3.6e-05 23.5 0.2 6.6e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 F-box domain NUP50 PF08911.11 EMC98677.1 - 1.4e-09 38.5 3.1 1.4e-09 38.5 3.1 6.9 5 1 0 5 5 5 2 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 EMC98677.1 - 8.5e-05 22.8 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain SCP2 PF02036.17 EMC98678.1 - 1.9e-21 76.4 1.4 2.3e-21 76.2 1.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EMC98678.1 - 5.8e-05 23.4 0.2 6.9e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal YgaB PF14182.6 EMC98678.1 - 0.096 13.1 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 YgaB-like protein PEP_mutase PF13714.6 EMC98680.1 - 4.7e-43 147.4 0.1 5.4e-43 147.2 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EMC98680.1 - 1.1e-19 70.3 0.2 1.6e-19 69.8 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family S-methyl_trans PF02574.16 EMC98680.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase MFS_1 PF07690.16 EMC98681.1 - 1.7e-36 125.9 34.4 1.7e-36 125.9 34.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98681.1 - 1.8e-11 43.6 5.0 1.8e-11 43.6 5.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMC98681.1 - 3.3e-07 29.1 2.8 6.6e-07 28.1 2.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.12 EMC98681.1 - 7.2 6.0 20.4 0.9 8.9 3.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF554) ABM PF03992.16 EMC98682.1 - 4.3e-05 23.5 0.1 6.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase AsnC_trans_reg2 PF17805.1 EMC98682.1 - 0.0064 16.6 0.1 0.01 16.0 0.1 1.2 1 0 0 1 1 1 1 AsnC-like ligand binding domain FemAB_like PF04339.12 EMC98682.1 - 0.017 14.2 0.2 0.019 14.1 0.2 1.0 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition Lge1 PF11488.8 EMC98682.1 - 0.073 13.3 0.7 0.16 12.2 0.4 1.8 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 EF1G PF00647.19 EMC98682.1 - 0.082 13.0 3.1 0.21 11.7 1.2 2.0 1 1 1 2 2 2 0 Elongation factor 1 gamma, conserved domain DUF812 PF05667.11 EMC98684.1 - 0.079 11.8 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cortex-I_coil PF09304.10 EMC98684.1 - 0.27 11.4 1.6 14 5.9 0.3 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil CLTH PF10607.9 EMC98685.1 - 6.8e-31 107.2 0.0 3.2e-30 105.0 0.0 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EMC98685.1 - 2.3e-08 33.9 0.3 5.5e-08 32.7 0.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EMC98685.1 - 0.014 15.3 0.4 0.029 14.3 0.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EMC98685.1 - 0.021 15.1 0.7 0.037 14.4 0.7 1.4 1 0 0 1 1 1 0 Ring finger domain Rtf2 PF04641.12 EMC98685.1 - 0.052 12.9 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_4 PF14447.6 EMC98685.1 - 0.058 13.3 0.5 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TMEM247 PF15444.6 EMC98685.1 - 0.064 13.3 0.7 11 6.1 0.2 2.3 1 1 1 2 2 2 0 Transmembrane protein 247 Phage_Mu_Gam PF07352.12 EMC98685.1 - 0.069 13.1 0.2 0.18 11.7 0.0 1.8 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Vps16_C PF04840.12 EMC98685.1 - 0.089 11.8 1.2 0.23 10.5 0.1 2.0 2 1 0 2 2 2 0 Vps16, C-terminal region zf-C3HC4 PF00097.25 EMC98685.1 - 0.091 12.7 0.7 0.16 11.8 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MIP-T3_C PF17749.1 EMC98685.1 - 0.092 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Plasmid_RAQPRD PF09686.10 EMC98685.1 - 0.095 12.9 0.2 0.35 11.1 0.2 2.0 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) zf-Nse PF11789.8 EMC98685.1 - 0.43 10.4 1.7 0.98 9.3 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Laminin_II PF06009.12 EMC98685.1 - 0.62 10.1 2.7 4.4 7.3 0.1 2.8 2 1 1 3 3 3 0 Laminin Domain II DUF1043 PF06295.12 EMC98685.1 - 0.82 9.7 3.2 0.62 10.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Syntaxin_2 PF14523.6 EMC98685.1 - 0.93 9.9 2.8 1.3 9.4 0.8 2.0 2 0 0 2 2 2 0 Syntaxin-like protein ADIP PF11559.8 EMC98686.1 - 8.1e-35 120.2 15.6 8.1e-35 120.2 15.6 1.8 3 0 0 3 3 1 1 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 EMC98686.1 - 0.024 14.9 0.5 0.024 14.9 0.5 3.6 3 1 0 3 3 2 0 ABC transporter C-terminal domain Spc7 PF08317.11 EMC98686.1 - 0.027 13.4 14.3 0.01 14.8 8.9 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF3829 PF12889.7 EMC98686.1 - 0.029 13.9 3.1 0.055 12.9 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2935 PF11155.8 EMC98686.1 - 0.029 14.7 0.8 0.43 10.9 0.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) bZIP_1 PF00170.21 EMC98686.1 - 0.033 14.3 14.3 2.3 8.4 0.1 3.6 2 1 2 4 4 4 0 bZIP transcription factor DUF390 PF04094.14 EMC98686.1 - 0.052 11.9 13.4 0.0087 14.4 9.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF390) Csm1_N PF18504.1 EMC98686.1 - 0.094 13.1 14.0 2.4 8.6 3.3 4.4 2 1 2 4 4 4 0 Csm1 N-terminal domain Baculo_PEP_C PF04513.12 EMC98686.1 - 0.14 12.2 5.7 3.2 7.8 0.8 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 EMC98686.1 - 0.15 12.5 0.4 0.15 12.5 0.4 3.1 3 1 1 4 4 2 0 Lipoprotein leucine-zipper DUF724 PF05266.14 EMC98686.1 - 0.27 11.0 10.8 0.41 10.5 8.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 EMC98686.1 - 0.27 8.7 14.3 5.5 4.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3810 PF12725.7 EMC98686.1 - 0.53 9.6 2.8 0.76 9.1 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Muted PF14942.6 EMC98686.1 - 0.53 10.6 0.0 0.53 10.6 0.0 2.9 3 1 0 3 3 3 0 Organelle biogenesis, Muted-like protein Golgin_A5 PF09787.9 EMC98686.1 - 0.58 9.6 17.2 0.1 12.0 12.5 2.0 2 1 0 2 2 2 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 EMC98686.1 - 0.76 7.6 2.8 1 7.2 2.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PhoU PF01895.19 EMC98686.1 - 0.85 10.1 9.4 28 5.3 0.2 3.9 3 1 1 4 4 3 0 PhoU domain Fez1 PF06818.15 EMC98686.1 - 0.98 9.8 18.3 1.2 9.6 13.6 2.5 2 1 0 2 2 2 0 Fez1 DUF641 PF04859.12 EMC98686.1 - 1.3 9.3 17.6 4 7.8 4.1 3.6 2 2 1 3 3 3 0 Plant protein of unknown function (DUF641) TMF_TATA_bd PF12325.8 EMC98686.1 - 1.4 9.2 17.6 12 6.2 0.1 3.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding LXG PF04740.12 EMC98686.1 - 1.7 8.3 9.8 1.3 8.7 0.5 3.7 2 2 2 4 4 4 0 LXG domain of WXG superfamily DUF4407 PF14362.6 EMC98686.1 - 1.8 7.8 18.0 2.8 7.2 15.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CdvA PF18822.1 EMC98686.1 - 2 8.2 11.4 0.27 11.1 2.2 3.7 4 1 1 5 5 5 0 CdvA-like coiled-coil domain Rootletin PF15035.6 EMC98686.1 - 2.1 8.3 16.8 0.16 12.0 10.2 2.3 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 EMC98686.1 - 2.2 8.8 23.3 0.41 11.2 15.5 3.1 2 2 1 3 3 3 0 Apg6 coiled-coil region Pex19 PF04614.12 EMC98686.1 - 2.5 7.8 9.3 0.98 9.1 5.8 1.8 2 0 0 2 2 2 0 Pex19 protein family DUF4061 PF13270.6 EMC98686.1 - 2.7 8.4 8.7 0.75 10.1 2.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) Spc24 PF08286.11 EMC98686.1 - 6.2 7.1 14.4 3.2 8.0 2.4 3.5 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 Bacillus_HBL PF05791.11 EMC98686.1 - 6.4 6.6 8.6 1.9 8.3 1.7 3.0 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CENP-H PF05837.12 EMC98686.1 - 6.6 7.2 17.3 3.4 8.1 8.6 3.4 3 1 1 4 4 4 0 Centromere protein H (CENP-H) RasGAP_C PF03836.15 EMC98686.1 - 7.3 6.7 11.0 84 3.3 9.6 2.8 2 1 0 2 2 2 0 RasGAP C-terminus VPS38 PF17649.1 EMC98686.1 - 7.8 5.3 9.7 9.1 5.0 1.5 2.0 1 1 1 2 2 2 0 Vacuolar protein sorting 38 Nup88 PF10168.9 EMC98686.1 - 8.7 4.0 11.1 8.6 4.0 9.7 1.6 2 0 0 2 2 2 0 Nuclear pore component Scytalone_dh PF02982.14 EMC98687.1 - 1.4e-75 252.5 2.7 1.6e-75 252.3 2.7 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EMC98687.1 - 3.1e-08 33.8 1.4 3.9e-08 33.5 1.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain LPD23 PF18838.1 EMC98687.1 - 0.025 14.3 0.4 0.067 13.0 0.4 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 AMPK1_CBM PF16561.5 EMC98689.1 - 7.1e-05 22.9 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF4682 PF15733.5 EMC98689.1 - 0.0093 16.6 2.1 0.018 15.7 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4682) Tub_N PF16322.5 EMC98689.1 - 0.11 12.9 9.7 0.2 12.1 9.7 1.4 1 0 0 1 1 1 0 Tubby N-terminal DUF951 PF06107.11 EMC98689.1 - 0.88 9.5 2.9 1.9 8.5 2.9 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DNA_pol_phi PF04931.13 EMC98689.1 - 3.4 5.7 5.3 3.8 5.5 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Herpes_pp85 PF04637.12 EMC98689.1 - 3.5 5.9 4.6 4.8 5.5 4.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4262 PF14081.6 EMC98690.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) ADH_zinc_N PF00107.26 EMC98696.1 - 6.3e-22 77.9 0.0 9.7e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMC98696.1 - 2.1e-18 66.2 0.0 3.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EMC98696.1 - 3.1e-07 31.5 0.0 5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Maf PF02545.14 EMC98697.1 - 9e-50 168.8 0.0 1e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Fungal_trans PF04082.18 EMC98698.1 - 1.5e-23 83.2 0.0 2.4e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC98698.1 - 4.3e-08 33.1 13.4 7.3e-08 32.4 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TolA_bind_tri PF16331.5 EMC98698.1 - 0.22 11.6 4.4 0.45 10.6 1.6 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation MR_MLE_C PF13378.6 EMC98699.1 - 3.8e-42 144.3 0.0 5e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMC98699.1 - 3e-08 33.9 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain RGS PF00615.19 EMC98701.1 - 3e-11 43.6 0.0 1.4e-08 35.0 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain MRI PF15325.6 EMC98701.1 - 3.7 8.7 4.6 5 8.3 3.2 1.8 1 1 1 2 2 2 0 Modulator of retrovirus infection Glyco_hydro_12 PF01670.16 EMC98704.1 - 1.2e-72 244.3 13.4 1.4e-72 244.1 13.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF2205 PF10224.9 EMC98706.1 - 5.5e-34 116.0 0.2 7.4e-34 115.6 0.2 1.2 1 0 0 1 1 1 1 Short coiled-coil protein Arrestin_N PF00339.29 EMC98707.1 - 9.9e-07 28.9 0.0 5.4e-06 26.5 0.0 2.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EMC98707.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.12 EMC98707.1 - 0.00013 20.9 1.1 0.012 14.5 0.5 2.8 2 1 1 3 3 3 2 Bul1 N terminus DUF5134 PF17197.4 EMC98708.1 - 1.7 8.6 6.8 0.92 9.4 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) UPF0242 PF06785.11 EMC98708.1 - 3.5 7.7 5.9 8.6 6.4 0.5 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NPR2 PF06218.11 EMC98710.1 - 6e-102 341.7 0.0 5.8e-101 338.4 0.0 2.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 DDE_Tnp_1_2 PF13586.6 EMC98710.1 - 0.014 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain NPR3 PF03666.13 EMC98710.1 - 0.04 12.7 0.0 0.13 11.0 0.1 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 VIT1 PF01988.19 EMC98711.1 - 3.6e-41 141.4 1.0 4.1e-41 141.2 1.0 1.0 1 0 0 1 1 1 1 VIT family DUF998 PF06197.13 EMC98711.1 - 0.032 13.9 6.0 0.042 13.4 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Sec6 PF06046.13 EMC98711.1 - 0.078 11.3 0.1 0.098 11.0 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 Glyco_tran_WbsX PF14307.6 EMC98714.1 - 0.042 13.3 0.0 0.042 13.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase WbsX Esterase_phd PF10503.9 EMC98715.1 - 3.7e-05 23.3 0.1 7.5e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EMC98715.1 - 0.032 13.5 0.1 0.083 12.1 0.1 1.8 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EMC98715.1 - 0.12 12.1 0.1 1.1 9.0 0.1 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1100 PF06500.11 EMC98715.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) VWA_3 PF13768.6 EMC98716.1 - 4.4e-30 104.7 0.1 1.6e-28 99.6 0.0 2.7 3 0 0 3 3 3 1 von Willebrand factor type A domain VIT PF08487.10 EMC98716.1 - 8.7e-28 96.8 0.3 3.8e-27 94.7 0.1 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EMC98716.1 - 2.8e-12 47.2 0.1 4.8e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EMC98716.1 - 2.8e-10 40.0 0.0 8.3e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 EMC98716.1 - 2.1e-09 38.0 0.0 5e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EMC98716.1 - 0.00052 19.5 0.0 0.00096 18.6 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Rad4 PF03835.15 EMC98716.1 - 0.14 11.8 0.3 0.27 10.9 0.3 1.4 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain HLH PF00010.26 EMC98717.1 - 9.3e-07 28.7 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Membr_traf_MHD PF10540.9 EMC98718.1 - 1e-19 71.2 1.1 3.1e-09 37.2 0.7 2.8 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EMC98718.1 - 1.9e-15 57.0 0.0 4.5e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.16 EMC98719.1 - 2e-28 99.4 71.4 1.2e-22 80.3 44.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98719.1 - 0.0012 17.8 38.0 0.022 13.6 13.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter fn3 PF00041.21 EMC98720.1 - 0.00068 19.9 0.1 0.0025 18.1 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EMC98720.1 - 0.41 11.2 2.0 2.1 9.0 0.0 3.0 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain LNS2 PF08235.13 EMC98721.1 - 2.9e-91 304.9 0.0 4.4e-91 304.4 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EMC98721.1 - 6.4e-42 141.7 0.0 1.4e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Chromo PF00385.24 EMC98722.1 - 1.6e-12 47.1 2.7 4.3e-05 23.3 0.1 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF3445 PF11927.8 EMC98723.1 - 7.5e-70 235.1 0.0 9.4e-70 234.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) FMO-like PF00743.19 EMC98724.1 - 2.9e-15 55.7 0.0 1.1e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMC98724.1 - 1.5e-14 54.0 0.0 4.9e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC98724.1 - 5.9e-14 52.0 0.0 1.1e-12 47.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMC98724.1 - 2.8e-08 33.3 0.1 3e-05 23.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EMC98724.1 - 4.1e-08 33.3 0.0 8.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC98724.1 - 1.6e-06 27.9 0.0 3.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EMC98724.1 - 0.00015 21.8 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EMC98724.1 - 0.00048 20.6 0.0 0.24 12.0 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC98724.1 - 0.0015 18.5 0.0 0.024 14.6 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EMC98724.1 - 0.0023 17.2 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EMC98724.1 - 0.0086 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EMC98724.1 - 0.15 10.7 0.4 0.31 9.7 0.4 1.5 1 0 0 1 1 1 0 HI0933-like protein PRP38 PF03371.15 EMC98726.1 - 2.4e-58 196.8 0.0 2.9e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Acyl-CoA_dh_1 PF00441.24 EMC98728.1 - 1.8e-39 135.4 4.6 2.9e-39 134.7 4.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMC98728.1 - 5e-31 107.7 0.3 2.1e-30 105.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EMC98728.1 - 6.8e-24 83.9 0.0 1.8e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMC98728.1 - 9.5e-17 61.5 1.5 9.5e-17 61.5 1.5 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EMC98728.1 - 0.045 13.4 0.1 0.11 12.2 0.1 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Cytochrome_P460 PF16694.5 EMC98730.1 - 0.0086 16.4 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome P460 ATG16 PF08614.11 EMC98730.1 - 0.036 14.3 6.3 0.078 13.2 6.3 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Pkinase PF00069.25 EMC98731.1 - 4.1e-60 203.4 0.0 6.7e-60 202.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC98731.1 - 1.6e-36 125.9 0.0 4e-32 111.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EMC98731.1 - 1.4e-07 31.2 0.1 0.00011 21.6 0.1 2.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EMC98731.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EMC98731.1 - 0.00063 19.4 0.0 0.00089 18.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EMC98731.1 - 0.0011 18.0 0.4 0.0024 16.9 0.2 1.5 1 1 1 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EMC98731.1 - 0.0079 15.6 0.1 0.018 14.4 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HMA PF00403.26 EMC98732.1 - 1.2e-50 169.8 0.3 7.6e-13 48.7 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 EMC98732.1 - 6.4e-50 169.2 3.0 3.2e-49 166.9 2.7 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EMC98732.1 - 1.1e-37 130.3 2.6 2.5e-37 129.2 0.5 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 EMC98732.1 - 0.0009 19.3 1.5 0.37 10.9 0.0 4.2 4 0 0 4 4 4 1 B12 binding domain Hydrolase_3 PF08282.12 EMC98732.1 - 0.0037 17.0 0.5 0.0097 15.7 0.5 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LPD22 PF18834.1 EMC98732.1 - 0.01 16.0 1.3 8.9 6.6 0.3 3.5 4 0 0 4 4 4 0 Large polyvalent protein associated domain 22 MafB19-deam PF14437.6 EMC98732.1 - 0.26 11.0 0.9 13 5.5 0.0 3.1 2 1 0 3 3 3 0 MafB19-like deaminase DUF678 PF05077.12 EMC98732.1 - 3.4 7.9 5.4 22 5.3 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF678) Redoxin PF08534.10 EMC98733.1 - 3.6e-22 78.7 0.0 4.4e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EMC98733.1 - 1e-11 44.8 0.0 5.5e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family PET117 PF15786.5 EMC98734.1 - 1.2e-24 86.4 4.5 1.3e-24 86.2 4.5 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Histidinol_dh PF00815.20 EMC98735.1 - 5.2e-159 529.6 3.7 9.2e-159 528.8 3.7 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EMC98735.1 - 1.2e-25 89.2 0.2 2.4e-25 88.2 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase Pkinase PF00069.25 EMC98735.1 - 3.8e-14 52.7 0.0 1.2e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain PRA-PH PF01503.17 EMC98735.1 - 1.2e-13 51.3 0.1 2.8e-13 50.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Pkinase_Tyr PF07714.17 EMC98735.1 - 9.9e-08 31.6 0.0 2.2e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase MazG PF03819.17 EMC98735.1 - 0.024 14.8 0.2 0.06 13.5 0.2 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 EMC98735.1 - 0.17 12.1 0.2 0.45 10.8 0.2 1.6 1 0 0 1 1 1 0 MazG-like family Cellulase PF00150.18 EMC98736.1 - 6.3e-44 150.5 0.6 8.2e-44 150.1 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TFIID-31kDa PF02291.15 EMC98737.1 - 2.1e-43 147.2 0.0 2.9e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Utp11 PF03998.13 EMC98738.1 - 5.8e-54 183.6 17.4 7.6e-54 183.2 17.4 1.1 1 0 0 1 1 1 1 Utp11 protein RRN3 PF05327.11 EMC98738.1 - 1 7.8 7.3 1.4 7.3 7.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 adh_short PF00106.25 EMC98739.1 - 2e-36 125.3 0.0 2.4e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC98739.1 - 4.4e-28 98.4 0.0 5e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC98739.1 - 6.7e-11 42.4 0.2 3.2e-10 40.2 0.2 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC98739.1 - 0.0099 15.4 0.0 0.12 11.8 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMC98739.1 - 0.038 14.2 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Lactamase_B_2 PF12706.7 EMC98741.1 - 6e-09 35.7 0.0 2.1e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 EMC98741.1 - 6.5e-05 23.1 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 EMC98741.1 - 0.0064 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EMC98741.1 - 0.15 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain ApbA_C PF08546.11 EMC98742.1 - 7e-28 97.3 0.0 1.1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EMC98742.1 - 4.1e-27 94.7 0.0 5.3e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 EMC98742.1 - 0.056 13.0 1.7 0.24 10.9 1.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EMC98742.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sec7 PF01369.20 EMC98743.1 - 5e-35 120.8 0.1 7.9e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EMC98743.1 - 8e-08 32.7 0.1 1.9e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EMC98743.1 - 1.1e-05 25.9 0.0 2.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 PH domain ATP-synt_D PF01813.17 EMC98743.1 - 0.025 14.4 1.4 0.05 13.4 1.4 1.6 1 0 0 1 1 1 0 ATP synthase subunit D MitMem_reg PF13012.6 EMC98746.1 - 1e-12 48.4 0.0 1.3e-11 44.9 0.0 2.3 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EMC98746.1 - 0.00031 20.7 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Voltage_CLC PF00654.20 EMC98747.1 - 1.9e-90 303.7 24.0 3.8e-90 302.7 24.0 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel adh_short PF00106.25 EMC98748.1 - 1.9e-22 79.7 0.4 2.7e-22 79.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC98748.1 - 1e-17 64.5 0.7 1.3e-17 64.1 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC98748.1 - 7.9e-06 25.9 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC98748.1 - 0.0011 18.5 0.4 0.0059 16.1 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CDKN3 PF05706.12 EMC98748.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) GDPD PF03009.17 EMC98749.1 - 1.8e-12 47.6 0.0 5.8e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family DUF2181 PF10223.9 EMC98749.1 - 0.01 15.3 0.0 0.028 13.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2181) Mcp5_PH PF12814.7 EMC98750.1 - 8.9e-45 151.7 0.3 8.9e-45 151.7 0.3 2.0 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EMC98750.1 - 0.00029 21.3 0.0 0.00063 20.2 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF1664 PF07889.12 EMC98750.1 - 0.11 12.6 26.4 0.11 12.5 0.5 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 EMC98750.1 - 0.5 10.6 37.0 0.45 10.7 2.1 5.5 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding zf-CCCH PF00642.24 EMC98751.1 - 1.4e-08 34.5 2.4 3.1e-08 33.3 2.4 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 EMC98751.1 - 4.4e-08 32.8 9.8 8.1e-08 32.0 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMC98751.1 - 1.5e-07 31.2 7.3 2.9e-07 30.2 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC98751.1 - 3.4e-07 30.2 7.4 6.3e-07 29.3 7.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMC98751.1 - 4.9e-07 29.5 10.6 8.6e-07 28.7 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC98751.1 - 1.9e-06 27.7 9.9 3.5e-06 26.9 9.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EMC98751.1 - 8e-06 26.1 7.2 1.5e-05 25.2 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 EMC98751.1 - 1.7e-05 24.7 5.4 4.3e-05 23.4 5.4 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_4 PF15227.6 EMC98751.1 - 7.9e-05 22.7 7.7 0.00017 21.6 7.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 EMC98751.1 - 0.00098 18.9 1.9 0.00098 18.9 1.9 2.0 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 EMC98751.1 - 0.0031 17.3 4.5 0.0059 16.4 4.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EMC98751.1 - 0.019 15.1 3.6 0.019 15.1 3.6 1.7 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 EMC98751.1 - 0.046 13.5 3.7 0.078 12.8 3.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_2 PF14608.6 EMC98751.1 - 0.056 13.9 2.5 0.13 12.8 2.5 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 EMC98751.1 - 0.39 11.0 4.4 0.83 10.0 4.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Histidinol_dh PF00815.20 EMC98752.1 - 3.6e-137 457.7 0.0 4.4e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase TRI12 PF06609.13 EMC98753.1 - 9e-26 90.4 22.9 1.2e-25 90.0 22.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EMC98753.1 - 4.4e-14 52.2 59.4 2e-11 43.5 52.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 EMC98754.1 - 2.5e-16 59.9 0.0 3.7e-16 59.3 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EMC98754.1 - 0.005 15.9 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.24 EMC98754.1 - 0.0066 15.8 0.3 0.24 10.6 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EMC98754.1 - 0.056 12.7 0.0 0.68 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CNP_C_terminal PF17839.1 EMC98754.1 - 0.11 13.2 0.0 0.22 12.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of cyclic nucleotide phosphodiesterase FAD_binding_3 PF01494.19 EMC98755.1 - 3.3e-15 56.2 0.3 2e-14 53.6 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.11 EMC98755.1 - 1.6e-11 44.3 0.0 2.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 EMC98755.1 - 2.3e-07 30.3 0.9 0.0014 18.0 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC98755.1 - 1.8e-05 24.8 1.0 5.8e-05 23.3 1.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMC98755.1 - 0.00063 18.9 3.4 0.00099 18.3 3.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EMC98755.1 - 0.0021 17.5 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EMC98755.1 - 0.0061 16.2 1.9 0.012 15.2 1.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EMC98755.1 - 0.0067 15.8 0.3 1.5 8.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EMC98755.1 - 0.034 13.0 0.2 0.92 8.3 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 EMC98755.1 - 0.036 13.1 1.6 0.06 12.4 1.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EMC98755.1 - 0.046 12.4 0.8 0.093 11.4 0.8 1.5 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EMC98755.1 - 0.1 11.9 0.2 0.19 11.0 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EMC98755.1 - 0.19 12.3 0.3 0.7 10.5 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4503 PF14951.6 EMC98756.1 - 0.0087 14.6 0.3 0.01 14.3 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) Aldedh PF00171.22 EMC98757.1 - 2.4e-07 29.7 0.6 7.3e-07 28.1 0.6 1.7 1 1 1 2 2 2 1 Aldehyde dehydrogenase family LigB PF02900.18 EMC98759.1 - 1.5e-12 47.1 0.0 2.7e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MR_MLE_C PF13378.6 EMC98760.1 - 1.4e-56 191.5 0.4 2.2e-56 190.9 0.4 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMC98760.1 - 4.5e-25 88.1 0.0 4.4e-23 81.7 0.0 2.3 2 0 0 2 2 2 2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_S15 PF02129.18 EMC98761.1 - 7.1e-41 140.6 0.0 1e-40 140.0 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EMC98761.1 - 6e-35 121.2 0.1 1.2e-34 120.3 0.1 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 EMC98761.1 - 0.0049 16.2 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ApbA_C PF08546.11 EMC98762.1 - 2.4e-29 102.1 0.0 3.9e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EMC98762.1 - 2e-27 95.7 0.0 4.2e-27 94.7 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EMC98762.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.18 EMC98763.1 - 1.4e-10 40.6 0.1 2.4e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EMC98763.1 - 3.1e-09 36.8 8.7 0.00038 20.8 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMC98763.1 - 4.6e-07 30.0 7.1 8.6e-06 25.9 1.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain Zn_clus PF00172.18 EMC98763.1 - 8.5e-05 22.6 13.0 0.00025 21.1 13.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EMC98763.1 - 0.00018 22.1 17.2 0.0017 19.0 0.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMC98763.1 - 0.0019 18.1 6.9 0.21 11.6 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EMC98763.1 - 0.0032 17.8 1.2 1.1 9.8 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EMC98763.1 - 0.39 11.1 6.4 0.55 10.6 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EMC98763.1 - 2.7 8.0 6.7 7.9 6.5 0.1 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 EMC98763.1 - 4.1 7.9 7.2 1.4 9.4 1.3 3.0 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger MFS_1 PF07690.16 EMC98764.1 - 1.7e-27 96.3 39.5 6.1e-26 91.2 25.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98764.1 - 8.8e-10 38.0 1.0 8.8e-10 38.0 1.0 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1751 PF08551.10 EMC98764.1 - 0.027 15.0 0.1 0.027 15.0 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) MpPF26 PF07666.11 EMC98764.1 - 0.069 13.3 3.0 0.073 13.2 0.1 2.4 2 0 0 2 2 2 0 M penetrans paralogue family 26 RRN9 PF10680.9 EMC98764.1 - 0.088 13.1 1.3 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor DUF2868 PF11067.8 EMC98764.1 - 0.17 11.4 2.8 0.15 11.6 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) DUF2207 PF09972.9 EMC98764.1 - 2.5 6.8 4.6 7.9 5.1 4.6 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 EMC98764.1 - 7.1 6.5 7.9 5.2 7.0 0.4 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Glyoxalase PF00903.25 EMC98765.1 - 2.3e-06 27.8 2.7 4.8e-06 26.8 1.8 2.0 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMC98765.1 - 0.0025 18.1 0.5 0.012 15.9 0.1 2.3 2 2 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADC PF06314.11 EMC98766.1 - 2e-11 43.9 0.0 2.3e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Peptidase_S15 PF02129.18 EMC98769.1 - 1.8e-40 139.3 0.7 2.6e-40 138.7 0.7 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EMC98769.1 - 1.9e-37 129.4 0.0 2.9e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Syja_N PF02383.18 EMC98769.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 SacI homology domain Cupin_2 PF07883.11 EMC98770.1 - 9.3e-09 34.9 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain p450 PF00067.22 EMC98771.1 - 2.6e-67 227.6 0.0 3.2e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 EMC98772.1 - 1.9e-83 280.6 0.0 2.5e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC98772.1 - 0.011 15.0 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC98772.1 - 0.073 12.1 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain PUF PF00806.19 EMC98773.1 - 1.2e-28 97.2 0.0 1.7e-05 24.3 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EMC98773.1 - 2.8e-11 43.1 0.0 8.4e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 EMC98773.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Methyltransf_16 PF10294.9 EMC98774.1 - 1.4e-21 77.0 0.0 2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EMC98774.1 - 1.8e-07 30.9 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EMC98774.1 - 8e-07 28.8 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EMC98774.1 - 1.3e-05 25.8 0.0 6.1e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EMC98774.1 - 0.00063 19.5 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.20 EMC98774.1 - 0.00091 18.4 0.0 0.0021 17.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 EMC98774.1 - 0.0021 18.8 0.0 0.0038 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMC98774.1 - 0.011 15.4 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EMC98774.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EMC98774.1 - 0.029 14.2 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EMC98774.1 - 0.062 14.0 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EMC98774.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ribosomal_S24e PF01282.19 EMC98775.1 - 3.9e-35 119.7 0.0 7.7e-35 118.7 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Bap31 PF05529.12 EMC98778.1 - 1e-49 167.8 8.4 1.3e-49 167.5 8.4 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EMC98778.1 - 1.4e-11 44.2 2.3 1.4e-11 44.2 0.2 2.0 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4349 PF14257.6 EMC98778.1 - 0.0063 16.0 0.2 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) KASH_CCD PF14662.6 EMC98778.1 - 0.075 12.8 0.6 0.16 11.8 0.6 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 EMC98778.1 - 0.1 12.4 6.9 2.2 8.1 0.4 3.4 2 1 1 3 3 3 0 Septum formation initiator Dus PF01207.17 EMC98779.1 - 3.5e-35 121.6 0.0 7e-25 87.8 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 EMC98779.1 - 4.4e-05 23.2 7.4 0.00088 19.0 0.2 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EMC98779.1 - 0.00044 20.2 9.5 0.036 14.1 1.1 2.9 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EMC98779.1 - 0.018 14.9 4.9 0.53 10.3 0.2 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Toxin_20 PF08089.11 EMC98779.1 - 2.1 8.6 5.1 7 6.8 5.1 1.9 1 1 0 1 1 1 0 Huwentoxin-II family Torus PF16131.5 EMC98779.1 - 4.4 8.1 6.0 2.4 8.9 0.7 2.3 1 1 1 2 2 2 0 Torus domain Amidohydro_2 PF04909.14 EMC98780.1 - 1.6e-26 93.8 0.9 3.3e-25 89.5 0.9 2.0 1 1 0 1 1 1 1 Amidohydrolase adh_short_C2 PF13561.6 EMC98781.1 - 7.3e-63 212.2 0.0 8.5e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC98781.1 - 4.8e-43 146.9 0.1 5.7e-43 146.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC98781.1 - 2e-10 40.9 0.3 3e-10 40.3 0.3 1.2 1 0 0 1 1 1 1 KR domain DEAD PF00270.29 EMC98782.1 - 8e-27 94.1 0.0 1.3e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC98782.1 - 7.1e-24 84.3 0.0 2.2e-23 82.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC98782.1 - 0.00019 21.5 0.0 0.00044 20.3 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATP-synt_G PF04718.15 EMC98783.1 - 3.6e-32 111.2 3.8 1.3e-31 109.4 0.4 2.8 2 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF883 PF05957.13 EMC98783.1 - 0.0013 19.3 6.4 0.058 14.0 5.1 2.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) LPD30 PF18850.1 EMC98783.1 - 0.055 13.2 0.5 0.096 12.4 0.1 1.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 30 Alanine_zipper PF11839.8 EMC98783.1 - 0.13 12.6 0.5 0.13 12.6 0.5 3.1 2 1 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein ApoLp-III PF07464.11 EMC98783.1 - 0.5 10.4 6.4 1.4 9.0 3.0 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Miga PF10265.9 EMC98783.1 - 0.68 8.8 5.3 0.85 8.5 5.3 1.1 1 0 0 1 1 1 0 Mitoguardin T3SS_needle_F PF09392.10 EMC98783.1 - 6.3 7.1 7.0 2.6 8.3 0.4 3.0 2 1 1 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF3306 PF11748.8 EMC98783.1 - 6.6 7.6 7.5 5.1 8.0 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RNA_pol_Rpc4 PF05132.14 EMC98783.1 - 8.8 6.7 9.6 0.6 10.5 2.6 2.1 2 1 0 2 2 2 0 RNA polymerase III RPC4 Glyco_tranf_2_3 PF13641.6 EMC98785.1 - 2.7e-31 109.3 0.2 3.4e-31 108.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMC98785.1 - 2.5e-08 33.6 0.0 1.3e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EMC98785.1 - 6.7e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 bZIP_1 PF00170.21 EMC98786.1 - 0.00029 20.9 3.0 0.00065 19.8 3.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor Anthrax-tox_M PF09156.10 EMC98786.1 - 0.17 11.2 0.0 0.85 8.9 0.0 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain Cellulase PF00150.18 EMC98788.1 - 1.7e-15 57.2 4.7 6.2e-15 55.4 4.7 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RICTOR_V PF14668.6 EMC98788.1 - 0.082 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Cerato-platanin PF07249.12 EMC98789.1 - 1.6e-53 179.9 2.3 1.9e-53 179.6 2.3 1.0 1 0 0 1 1 1 1 Cerato-platanin DUF4788 PF16032.5 EMC98789.1 - 0.18 10.7 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) HAMP PF00672.25 EMC98791.1 - 6.7e-43 144.9 17.9 1.6e-08 34.8 0.2 7.8 6 1 1 7 7 7 6 HAMP domain HATPase_c PF02518.26 EMC98791.1 - 2.7e-28 98.7 2.3 4.2e-28 98.1 0.2 2.5 3 0 0 3 3 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMC98791.1 - 1.4e-27 96.0 0.9 8.6e-27 93.5 0.7 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EMC98791.1 - 6.7e-16 58.1 0.4 6.7e-16 58.1 0.4 4.4 5 0 0 5 5 4 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 EMC98791.1 - 9.2e-11 41.5 8.9 0.0012 18.0 1.5 5.0 1 1 3 4 4 4 3 Autophagy protein Apg17 DUF3829 PF12889.7 EMC98791.1 - 0.00057 19.5 13.0 0.013 15.0 0.4 4.5 4 1 1 5 5 5 2 Protein of unknown function (DUF3829) DUF4279 PF14106.6 EMC98791.1 - 0.0015 18.8 0.1 12 6.2 0.0 4.7 5 0 0 5 5 4 0 Domain of unknown function (DUF4279) DUF948 PF06103.11 EMC98791.1 - 0.0092 16.2 49.0 0.88 9.9 0.6 9.6 3 3 5 8 8 8 3 Bacterial protein of unknown function (DUF948) SpoIIID PF12116.8 EMC98791.1 - 0.034 14.2 2.4 32 4.7 0.0 4.8 4 0 0 4 4 4 0 Stage III sporulation protein D DUF4795 PF16043.5 EMC98791.1 - 0.12 12.0 0.1 0.12 12.0 0.1 5.2 1 1 5 6 6 6 0 Domain of unknown function (DUF4795) EDR1 PF14381.6 EMC98791.1 - 0.2 11.3 8.3 1.9 8.2 0.3 4.6 3 1 2 5 5 5 0 Ethylene-responsive protein kinase Le-CTR1 ApoLp-III PF07464.11 EMC98791.1 - 0.31 11.1 25.5 0.26 11.4 0.8 5.8 3 2 3 6 6 6 0 Apolipophorin-III precursor (apoLp-III) ubiquitin PF00240.23 EMC98791.1 - 0.36 10.6 2.4 7.8 6.3 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin family DUF1843 PF08898.10 EMC98791.1 - 0.42 11.2 10.5 30 5.2 0.1 6.1 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) ABC_tran_Xtn PF12848.7 EMC98791.1 - 0.67 10.0 3.0 3.5 7.7 3.0 2.3 1 0 0 1 1 1 0 ABC transporter RNA_polI_A14 PF08203.11 EMC98791.1 - 2.1 9.1 4.2 7.4 7.4 2.8 2.7 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF1759 PF03564.15 EMC98791.1 - 3.1 7.7 6.1 33 4.4 0.0 5.0 5 1 1 6 6 6 0 Protein of unknown function (DUF1759) WXG100 PF06013.12 EMC98791.1 - 4.7 7.5 28.8 12 6.2 0.0 7.7 5 1 3 8 8 8 0 Proteins of 100 residues with WXG Not3 PF04065.15 EMC98791.1 - 5.5 6.4 16.7 0.52 9.7 4.8 4.0 3 2 1 4 4 4 0 Not1 N-terminal domain, CCR4-Not complex component Glyco_hydro_31 PF01055.26 EMC98792.1 - 1.6e-146 489.0 6.6 2.1e-146 488.6 6.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EMC98792.1 - 6.8e-30 103.6 0.0 1.2e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EMC98792.1 - 0.00015 22.0 1.9 0.00043 20.6 0.5 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like AA_permease_2 PF13520.6 EMC98793.1 - 1.5e-30 106.4 34.3 1.8e-30 106.1 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC98793.1 - 3.2e-22 78.8 28.3 3.9e-22 78.5 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease TraX PF05857.11 EMC98793.1 - 3.5 7.6 11.9 0.12 12.4 4.3 2.2 3 0 0 3 3 3 0 TraX protein LigD_N PF13298.6 EMC98795.1 - 2.2e-32 111.5 1.5 2.5e-32 111.3 0.2 1.8 2 0 0 2 2 2 1 DNA polymerase Ligase (LigD) Barttin PF15462.6 EMC98795.1 - 0.26 11.0 1.1 0.53 10.0 1.1 1.4 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) zf-Tim10_DDP PF02953.15 EMC98796.1 - 2e-21 75.4 1.3 2.3e-21 75.2 1.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FAD_binding_8 PF08022.12 EMC98797.1 - 2.6e-23 82.2 0.0 5.4e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EMC98797.1 - 4.5e-21 75.6 0.0 7.7e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EMC98797.1 - 1.5e-20 73.6 9.1 1.5e-20 73.6 9.1 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EMC98797.1 - 0.021 15.1 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF1479 PF07350.12 EMC98799.1 - 8.6e-165 548.5 0.0 9.9e-165 548.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) TauD PF02668.16 EMC98799.1 - 0.01 15.6 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family PhyH PF05721.13 EMC98799.1 - 0.092 13.0 0.0 13 5.9 0.1 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_1 PF00232.18 EMC98800.1 - 2.8e-158 527.1 0.1 3.4e-158 526.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Mersacidin PF16934.5 EMC98800.1 - 0.21 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) bZIP_1 PF00170.21 EMC98801.1 - 0.0061 16.6 9.1 0.051 13.7 8.7 2.1 1 1 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 EMC98801.1 - 0.097 13.3 0.1 0.17 12.6 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 EMC98801.1 - 2.6 8.2 12.4 5.2 7.2 4.5 2.3 1 1 1 2 2 2 0 Basic region leucine zipper TetR_C_20 PF17925.1 EMC98801.1 - 3.8 7.9 7.9 0.48 10.7 0.5 2.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HAUS6_N PF14661.6 EMC98801.1 - 4.5 6.8 5.6 6.9 6.2 5.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DIOX_N PF14226.6 EMC98802.1 - 1.1e-33 116.5 0.0 1.2e-31 109.9 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMC98802.1 - 8.4e-13 48.7 0.0 1.6e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Noc2 PF03715.13 EMC98803.1 - 6.1e-118 393.4 0.0 9.3e-118 392.8 0.0 1.3 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 EMC98803.1 - 2.6 6.2 0.0 2.6 6.2 0.0 3.8 3 1 0 3 3 3 0 Nop14-like family Methyltransf_16 PF10294.9 EMC98804.1 - 5.7e-18 65.3 0.0 2.8e-14 53.2 0.0 2.9 4 0 0 4 4 4 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EMC98804.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EMC98804.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EMC98804.1 - 0.19 12.5 0.1 0.69 10.7 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain SET_assoc PF11767.8 EMC98806.1 - 0.14 11.8 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated PAF-AH_p_II PF03403.13 EMC98808.1 - 1.2e-43 149.1 0.0 2.3e-42 144.8 0.0 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EMC98808.1 - 1.1e-06 27.7 0.0 4.6e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EMC98808.1 - 2e-05 24.0 0.0 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EMC98808.1 - 3.2e-05 23.1 0.0 5.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase GATA PF00320.27 EMC98810.1 - 6.1e-16 57.7 4.9 1.3e-15 56.6 4.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 EMC98810.1 - 8.1e-14 51.7 0.0 1.8e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EMC98810.1 - 7.4e-10 38.8 0.0 1.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMC98810.1 - 3e-07 30.6 0.0 1.2e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 EMC98810.1 - 9.1e-06 25.8 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EMC98810.1 - 9.2e-06 25.9 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn-ribbon_8 PF09723.10 EMC98810.1 - 0.011 15.9 0.2 0.022 14.8 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF4428 PF14471.6 EMC98810.1 - 0.91 9.5 4.0 0.4 10.7 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) F-box-like PF12937.7 EMC98812.1 - 4.7e-07 29.6 0.0 1.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC98812.1 - 0.0014 18.4 0.1 2.3 8.2 0.0 2.7 2 0 0 2 2 2 2 F-box domain PhoLip_ATPase_C PF16212.5 EMC98814.1 - 1.1e-81 274.3 23.2 1.1e-81 274.3 23.2 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMC98814.1 - 9.8e-28 95.7 6.6 2.6e-27 94.3 6.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EMC98814.1 - 1.5e-10 41.0 0.0 7.4e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMC98814.1 - 8.4e-10 39.3 3.6 2.8e-06 27.8 1.3 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EMC98814.1 - 1.3e-06 28.1 1.3 1.8e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EMC98814.1 - 0.0047 16.7 0.1 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Zip PF02535.22 EMC98815.1 - 6.8e-29 101.1 1.9 1.6e-17 63.7 0.9 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter DctQ PF04290.12 EMC98815.1 - 0.4 10.6 4.3 0.21 11.5 1.5 1.9 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component PHO4 PF01384.20 EMC98815.1 - 0.64 9.0 8.1 0.18 10.8 2.6 2.3 1 1 1 2 2 2 0 Phosphate transporter family bVLRF1 PF18826.1 EMC98816.1 - 4.6e-62 208.3 0.1 8.2e-62 207.5 0.1 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EMC98816.1 - 2.8e-07 30.7 0.5 6.5e-07 29.5 0.5 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EMC98816.1 - 0.00097 19.5 0.9 0.0022 18.4 0.9 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EMC98816.1 - 0.0091 16.6 0.1 0.019 15.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC98816.1 - 0.16 12.6 0.1 0.38 11.4 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) adh_short_C2 PF13561.6 EMC98817.1 - 3e-46 157.9 0.0 1.9e-25 89.8 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC98817.1 - 1.5e-36 125.7 0.0 8.1e-21 74.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EMC98817.1 - 1.6e-06 28.2 0.1 7e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMC98817.1 - 0.0032 17.0 0.0 0.0063 16.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC98817.1 - 0.097 12.5 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 EMC98817.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_4 PF13439.6 EMC98817.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 HsbA PF12296.8 EMC98818.1 - 1.4e-18 67.4 1.4 2.1e-18 66.9 1.4 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Chlorosome_CsmC PF11098.8 EMC98818.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 2 0 0 2 2 2 0 Chlorosome envelope protein C PBP PF01161.20 EMC98820.1 - 2.7e-07 30.9 0.2 4.7e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Fungal_trans_2 PF11951.8 EMC98821.1 - 4.1e-08 32.5 0.3 6.3e-08 31.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC98821.1 - 5.5e-07 29.6 10.2 1.1e-06 28.7 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CfAFP PF05264.11 EMC98821.1 - 0.89 9.5 5.1 0.51 10.3 1.5 2.3 2 0 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Catalase PF00199.19 EMC98822.1 - 1.3e-26 93.7 0.8 4.6e-26 91.8 0.8 1.8 1 1 0 1 1 1 1 Catalase Ras PF00071.22 EMC98823.1 - 2.4e-45 154.0 0.0 2.9e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC98823.1 - 6.5e-31 107.0 0.0 1.1e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC98823.1 - 2.8e-13 49.7 0.0 4.9e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMC98823.1 - 1.7e-06 27.7 0.0 4.2e-06 26.4 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EMC98823.1 - 3.4e-05 23.3 0.0 4.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMC98823.1 - 4.3e-05 23.6 0.0 6.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EMC98823.1 - 0.0011 19.3 0.1 0.0036 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.9 EMC98823.1 - 0.0019 17.9 0.1 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EMC98823.1 - 0.002 17.6 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 EMC98823.1 - 0.0066 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EMC98823.1 - 0.0081 16.7 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMC98823.1 - 0.0084 16.0 0.0 0.073 13.0 0.0 2.1 1 1 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 EMC98823.1 - 0.022 14.7 0.0 0.074 13.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 EMC98823.1 - 0.026 14.8 0.1 0.13 12.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMC98823.1 - 0.097 12.9 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMC98823.1 - 0.12 12.4 0.1 0.29 11.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EMC98823.1 - 0.13 11.9 0.2 1.7 8.4 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_14 PF13173.6 EMC98823.1 - 0.19 11.7 0.1 0.33 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EMC98823.1 - 0.21 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 EMC98823.1 - 0.24 10.9 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyoxalase PF00903.25 EMC98824.1 - 1.2e-08 35.1 3.3 7e-06 26.3 2.4 2.8 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SET PF00856.28 EMC98825.1 - 1.1e-08 35.7 0.0 1.9e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 SET domain G-alpha PF00503.20 EMC98826.1 - 5.3e-108 361.3 0.2 6.1e-108 361.1 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EMC98826.1 - 2.7e-15 56.2 2.4 2e-10 40.4 0.1 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMC98826.1 - 9.1e-07 28.5 0.1 0.00012 21.6 0.2 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 EMC98826.1 - 0.029 13.7 0.0 0.075 12.4 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 EMC98826.1 - 0.03 14.5 0.1 5.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EMC98826.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EMC98826.1 - 0.15 11.6 0.0 0.72 9.4 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Pex24p PF06398.11 EMC98827.1 - 3.7e-81 273.0 0.9 5.4e-81 272.4 0.9 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 EMC98827.1 - 0.00013 20.6 1.2 0.24 9.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) Peptidase_C78 PF07910.13 EMC98829.1 - 3.4e-38 131.2 0.0 4.2e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 DUF2014 PF09427.10 EMC98830.1 - 6.9e-99 330.5 1.0 1.1e-98 329.8 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EMC98830.1 - 1.4e-14 53.8 0.5 2.8e-14 52.8 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCCAP PF15964.5 EMC98830.1 - 0.07 11.4 0.4 0.1 10.9 0.4 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family TMF_DNA_bd PF12329.8 EMC98830.1 - 0.22 11.5 1.3 0.39 10.7 0.4 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 EMC98830.1 - 0.26 10.1 1.4 0.4 9.5 1.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RRP36 PF06102.12 EMC98830.1 - 1 9.3 5.4 1.6 8.7 5.4 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 ECH_1 PF00378.20 EMC98832.1 - 2.7e-40 138.3 0.0 3.7e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMC98832.1 - 4.7e-23 82.2 0.2 2.6e-22 79.8 0.2 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Amidohydro_2 PF04909.14 EMC98833.1 - 5.9e-44 151.0 0.0 6.9e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase DUF4085 PF13315.6 EMC98834.1 - 0.042 13.5 0.2 0.056 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DnaJ PF00226.31 EMC98836.1 - 6.8e-12 45.3 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Solute_trans_a PF03619.16 EMC98837.1 - 3.4e-92 308.7 18.5 3.9e-92 308.5 18.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.11 EMC98837.1 - 1.7 8.9 10.5 0.42 10.8 3.0 2.6 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) WSC PF01822.19 EMC98838.1 - 4.5e-07 30.0 12.1 4.5e-07 30.0 12.1 2.3 2 0 0 2 2 2 1 WSC domain DHHW PF14286.6 EMC98838.1 - 0.29 10.4 5.8 0.52 9.6 5.8 1.3 1 0 0 1 1 1 0 DHHW protein Gram_pos_anchor PF00746.21 EMC98838.1 - 1.1 9.3 5.1 0.31 11.0 0.8 2.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif GREB1 PF15782.5 EMC98838.1 - 1.2 6.1 12.8 1.3 6.0 12.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 EMC98838.1 - 9.1 6.2 11.5 13 5.6 11.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAI16-like PF10257.9 EMC98839.1 - 1e-62 212.1 1.5 1.5e-62 211.5 1.5 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein IFRD PF05004.13 EMC98839.1 - 0.1 11.7 0.0 0.36 9.9 0.0 1.9 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Ubiq_cyt_C_chap PF03981.12 EMC98844.1 - 1.7e-33 115.7 1.3 2.6e-33 115.1 1.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone mRNA_cap_enzyme PF01331.19 EMC98845.1 - 3.1e-48 164.2 0.0 4.9e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EMC98845.1 - 4e-31 107.8 0.1 8e-31 106.9 0.1 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EMC98845.1 - 5.5e-05 22.9 0.0 0.0027 17.4 0.0 3.0 1 1 1 2 2 2 1 ATP dependent DNA ligase domain DUF1682 PF07946.14 EMC98845.1 - 0.51 9.5 4.1 0.8 8.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HEAT PF02985.22 EMC98847.1 - 4.8e-08 32.6 3.0 0.17 12.2 0.2 6.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EMC98847.1 - 1e-05 25.8 12.0 2.6e-05 24.5 1.0 5.8 6 1 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.6 EMC98847.1 - 0.00018 21.9 5.5 0.43 11.2 0.6 4.8 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 EMC98847.1 - 0.00047 20.2 0.1 1.2 9.2 0.0 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EMC98847.1 - 0.027 13.1 0.0 24 3.3 0.0 4.1 3 2 0 3 3 3 0 Adaptin N terminal region ketoacyl-synt PF00109.26 EMC98848.1 - 1.9e-60 204.6 6.1 2.9e-58 197.4 1.1 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMC98848.1 - 6.5e-37 126.2 2.0 1.3e-36 125.2 0.7 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EMC98848.1 - 6.9e-06 25.6 0.4 0.00024 20.6 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMC98848.1 - 0.00011 21.8 3.2 0.0022 17.6 0.2 3.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain NicO PF03824.16 EMC98849.1 - 5.7e-61 206.3 14.8 5.7e-61 206.3 14.8 1.4 2 0 0 2 2 2 1 High-affinity nickel-transport protein zf-C2H2 PF00096.26 EMC98850.1 - 2.8e-06 27.5 15.2 0.0046 17.3 2.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC98850.1 - 3.9e-06 27.2 13.7 0.11 13.4 0.7 3.5 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EMC98850.1 - 0.00075 19.7 0.2 0.00075 19.7 0.2 1.4 2 0 0 2 2 2 1 Aberrant zinc-finger IKKbetaNEMObind PF12179.8 EMC98851.1 - 0.16 12.1 0.3 0.22 11.6 0.3 1.2 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Defensin_2 PF01097.18 EMC98853.1 - 0.57 10.2 5.1 1.1 9.2 2.0 2.1 2 0 0 2 2 2 0 Arthropod defensin GCS PF03074.16 EMC98855.1 - 3.8e-172 572.7 0.0 5e-172 572.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.27 EMC98855.1 - 7.6e-15 54.2 5.3 1.7e-14 53.1 5.3 1.7 1 0 0 1 1 1 1 GATA zinc finger Hexapep PF00132.24 EMC98856.1 - 7.5e-13 47.6 14.9 7.4e-08 31.8 2.1 5.0 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMC98856.1 - 1.7e-08 34.0 5.4 6.9e-06 25.7 1.4 4.1 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EMC98856.1 - 0.0002 20.4 0.2 0.00031 19.8 0.2 1.3 1 1 0 1 1 1 1 L-fucokinase PI-PLC-X PF00388.19 EMC98857.1 - 6.7e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Meth_synt_2 PF01717.18 EMC98858.1 - 7.6e-11 41.9 0.0 1.6e-09 37.5 0.0 2.2 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain ADH_N PF08240.12 EMC98859.1 - 3.3e-25 88.1 3.3 7.8e-25 86.9 3.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC98859.1 - 5.3e-22 78.2 0.2 1.1e-21 77.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMC98859.1 - 7.5e-05 22.1 1.9 0.00013 21.3 1.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EMC98859.1 - 0.00058 20.1 0.1 0.0011 19.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 EMC98859.1 - 0.00078 19.0 0.0 0.0045 16.5 0.0 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMC98859.1 - 0.012 16.7 0.0 0.023 15.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 EMC98859.1 - 0.029 15.0 0.4 0.084 13.5 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EMC98859.1 - 0.031 13.8 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IGFBP PF00219.18 EMC98859.1 - 0.05 14.3 2.3 0.15 12.7 2.3 1.8 1 0 0 1 1 1 0 Insulin-like growth factor binding protein TrkA_N PF02254.18 EMC98859.1 - 0.064 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Pep_deformylase PF01327.21 EMC98859.1 - 0.099 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase 2-Hacid_dh_C PF02826.19 EMC98859.1 - 0.11 11.8 0.2 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EMC98859.1 - 0.24 11.3 2.7 3 7.7 1.2 2.2 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-synt_C PF00137.21 EMC98860.1 - 3.4e-35 120.2 33.5 5.2e-22 78.0 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Tetraspanin PF00335.20 EMC98860.1 - 1.9 8.2 7.4 2.7 7.6 7.4 1.2 1 0 0 1 1 1 0 Tetraspanin family Ribosomal_L7Ae PF01248.26 EMC98861.1 - 3.5e-25 87.6 0.0 4.1e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EMC98861.1 - 0.0026 17.6 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 EMC98861.1 - 0.0033 17.5 0.1 0.0044 17.1 0.1 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 Abhydrolase_3 PF07859.13 EMC98864.1 - 5e-57 193.2 0.0 7.6e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC98864.1 - 1.1e-05 24.5 0.1 3.4e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EMC98864.1 - 0.098 12.1 0.1 1.5 8.2 0.1 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family RhoGEF PF00621.20 EMC98865.1 - 1.6e-14 54.6 0.0 3e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 EMC98865.1 - 0.0062 17.0 0.1 0.021 15.3 0.0 2.0 2 0 0 2 2 2 1 PH domain CASP_C PF08172.12 EMC98865.1 - 0.017 14.5 0.5 0.034 13.5 0.5 1.5 1 0 0 1 1 1 0 CASP C terminal MFS_1 PF07690.16 EMC98866.1 - 8.3e-40 136.8 26.4 1e-39 136.5 26.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 EMC98866.1 - 0.29 10.9 0.1 0.29 10.9 0.1 2.7 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like TPR_12 PF13424.6 EMC98867.1 - 0.0099 16.2 0.8 0.072 13.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EMC98867.1 - 0.028 14.5 0.1 0.06 13.4 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EMC98867.1 - 0.032 14.4 1.7 2.5 8.4 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMC98867.1 - 0.053 13.4 0.8 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMC98867.1 - 0.06 13.2 2.8 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMC98867.1 - 0.8 9.4 3.0 0.39 10.4 0.2 2.0 2 0 0 2 2 2 0 TPR repeat zf-Tim10_DDP PF02953.15 EMC98869.1 - 1.8e-22 78.7 0.6 2.4e-22 78.4 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.8 EMC98869.1 - 0.15 12.5 0.4 0.2 12.1 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) RGS_DHEX PF18148.1 EMC98869.1 - 0.18 11.9 0.9 9.3 6.4 0.0 2.0 1 1 1 2 2 2 0 Regulator of G-protein signalling DHEX domain Endonuclease_NS PF01223.23 EMC98870.1 - 1e-65 221.7 0.0 1.2e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Ribonuc_L-PSP PF01042.21 EMC98873.1 - 4.5e-30 104.1 0.1 4.9e-30 104.0 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Nucleoside_tran PF01733.18 EMC98874.1 - 1.2e-33 116.8 0.2 4.3e-31 108.4 0.2 2.3 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 EMC98874.1 - 4.1e-05 22.7 17.1 0.0034 16.4 4.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PRA1 PF03208.19 EMC98874.1 - 0.092 12.4 5.2 0.89 9.2 0.6 2.6 2 1 0 2 2 2 0 PRA1 family protein PAP_assoc PF03828.19 EMC98876.1 - 2.5e-17 62.8 0.1 4.9e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EMC98876.1 - 1.5e-05 25.2 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EMC98876.1 - 0.047 13.8 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Isochorismatase PF00857.20 EMC98877.1 - 2e-32 112.8 0.0 2.6e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family SHD1 PF03983.12 EMC98878.1 - 0.0089 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 Isochorismatase PF00857.20 EMC98879.1 - 1.9e-24 86.8 0.0 1.2e-15 58.2 0.0 2.2 2 0 0 2 2 2 2 Isochorismatase family Mito_carr PF00153.27 EMC98880.1 - 9.6e-69 227.4 1.2 3.9e-23 81.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHFR_1 PF00186.19 EMC98881.1 - 5.8e-28 97.6 0.0 1.2e-26 93.3 0.0 2.1 1 1 0 1 1 1 1 Dihydrofolate reductase Orthopox_F14 PF06076.12 EMC98881.1 - 0.15 12.4 0.0 1.2 9.5 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus F14 protein COesterase PF00135.28 EMC98882.1 - 1.3e-81 275.1 0.3 1.7e-81 274.7 0.3 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC98882.1 - 4.8e-05 23.3 0.2 0.00041 20.3 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lyase_1 PF00206.20 EMC98883.1 - 1.9e-33 116.2 0.0 4.4e-33 115.0 0.0 1.7 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 EMC98883.1 - 5.1e-11 43.0 0.0 2.3e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Adenylosuccinate lyase C-terminus Crp PF00325.20 EMC98883.1 - 0.074 12.7 0.0 0.24 11.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF2439 PF10382.9 EMC98884.1 - 1.5e-26 92.5 0.2 2.6e-26 91.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) VGLL4 PF15245.6 EMC98884.1 - 0.25 11.4 3.5 0.28 11.2 0.2 2.4 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 P22_AR_N PF10547.9 EMC98885.1 - 0.082 13.2 0.3 0.69 10.3 0.1 2.3 1 1 1 2 2 2 0 P22_AR N-terminal domain Autophagy_N PF03986.13 EMC98886.1 - 3.2e-41 140.5 0.0 5.9e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EMC98886.1 - 6e-16 57.7 0.6 1.1e-15 56.9 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EMC98886.1 - 3.3e-13 50.0 0.3 6.2e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain zf-C3HC4_3 PF13920.6 EMC98887.1 - 1.5e-09 37.5 10.6 1.5e-09 37.5 10.6 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC98887.1 - 0.00046 20.0 9.1 0.0013 18.5 9.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 tRNA-synt_1b PF00579.25 EMC98887.1 - 0.21 10.9 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) MRP-L46 PF11788.8 EMC98889.1 - 4.1e-32 111.4 0.1 1.8e-31 109.4 0.1 2.1 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 LRR_4 PF12799.7 EMC98890.1 - 4.7e-35 119.0 20.8 5.1e-08 33.1 0.2 6.3 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMC98890.1 - 3.5e-24 84.3 49.3 3.8e-06 26.6 4.0 5.9 1 1 5 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 EMC98890.1 - 7.4e-15 54.9 17.8 3.2e-06 26.7 0.4 4.0 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 EMC98890.1 - 5e-05 23.0 9.8 3.8 7.8 0.1 6.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EMC98890.1 - 0.0021 18.4 22.7 12 6.9 0.9 9.0 7 3 0 7 7 7 1 Leucine Rich Repeat Zn_clus PF00172.18 EMC98891.1 - 2.4e-09 37.1 10.3 5.4e-09 36.0 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC98891.1 - 3.8e-05 22.9 0.0 0.00013 21.1 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain SYS1 PF09801.9 EMC98891.1 - 0.055 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network PPR_2 PF13041.6 EMC98893.1 - 0.0017 18.5 0.0 0.057 13.6 0.0 3.1 4 0 0 4 4 4 1 PPR repeat family DUF1582 PF07621.11 EMC98893.1 - 0.027 14.4 0.1 0.083 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) ANAPC_CDC26 PF10471.9 EMC98894.1 - 0.25 12.2 2.2 0.62 10.9 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Cpn60_TCP1 PF00118.24 EMC98896.1 - 5.6e-145 483.7 12.4 6.3e-145 483.5 12.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 EMC98896.1 - 0.0021 17.6 0.1 0.0077 15.8 0.1 2.0 1 0 0 1 1 1 1 Propionate catabolism activator Myc_N PF01056.18 EMC98896.1 - 0.069 13.0 1.7 0.09 12.7 0.3 1.8 2 0 0 2 2 2 0 Myc amino-terminal region TetR_C_14 PF17754.1 EMC98896.1 - 0.19 11.7 4.7 0.16 11.9 0.9 2.3 2 0 0 2 2 2 0 MftR C-terminal domain TPR_12 PF13424.6 EMC98897.1 - 0.24 11.7 2.6 20 5.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Oxidored_FMN PF00724.20 EMC98898.1 - 8e-42 143.7 0.0 1.1e-41 143.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.18 EMC98898.1 - 0.00024 20.2 0.0 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Dus PF01207.17 EMC98898.1 - 0.075 12.1 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) RRM_1 PF00076.22 EMC98899.1 - 1.4e-37 127.3 0.0 2.2e-11 43.4 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC98899.1 - 3.4e-14 52.4 0.0 0.0086 15.9 0.0 4.4 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 EMC98899.1 - 5.1e-08 32.5 12.3 5.1e-08 32.5 12.3 2.5 2 1 0 2 2 2 1 Putative RRM domain RRM_7 PF16367.5 EMC98899.1 - 9e-05 22.5 0.0 0.07 13.3 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif DUF4523 PF15023.6 EMC98899.1 - 0.003 17.4 0.0 0.7 9.7 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) RRM_3 PF08777.11 EMC98899.1 - 0.004 17.2 0.0 0.47 10.5 0.1 2.8 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 EMC98899.1 - 0.12 12.4 0.0 48 4.1 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif WAC_Acf1_DNA_bd PF10537.9 EMC98900.1 - 2.1e-27 95.6 0.0 2.1e-27 95.6 0.0 2.5 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EMC98900.1 - 1.2e-20 73.8 0.4 1.2e-20 73.8 0.4 3.0 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EMC98900.1 - 3.4e-14 52.9 0.2 8.1e-14 51.7 0.2 1.7 1 0 0 1 1 1 1 DDT domain Nmad5 PF18757.1 EMC98900.1 - 1.1 9.4 11.4 0.065 13.4 4.3 2.2 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 Alg6_Alg8 PF03155.15 EMC98901.1 - 5.4e-178 592.9 23.1 6.2e-178 592.7 23.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyco_hydro_47 PF01532.20 EMC98902.1 - 6e-174 579.2 0.0 7e-174 579.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sulfotransfer_4 PF17784.1 EMC98903.1 - 1.3e-36 126.5 0.0 2e-36 125.8 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain DAO PF01266.24 EMC98904.1 - 6.7e-38 131.2 1.4 7.6e-38 131.0 1.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC98904.1 - 0.00011 22.4 0.1 0.00034 20.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EMC98904.1 - 0.00026 20.3 0.3 0.00039 19.8 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EMC98904.1 - 0.00099 18.4 0.9 0.0017 17.7 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EMC98904.1 - 0.0038 16.3 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EMC98904.1 - 0.0039 17.7 1.3 0.008 16.7 1.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC98904.1 - 0.016 14.4 0.2 0.03 13.5 0.2 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EMC98904.1 - 0.017 14.5 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EMC98904.1 - 0.023 15.1 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EMC98904.1 - 0.027 14.4 0.4 0.043 13.7 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EMC98904.1 - 0.053 13.2 1.5 0.12 12.0 1.5 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 EMC98904.1 - 0.12 11.5 0.4 0.18 10.9 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 EMC98904.1 - 0.24 10.9 0.6 0.42 10.2 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PHD PF00628.29 EMC98905.1 - 6.8e-08 32.3 7.7 6.8e-08 32.3 7.7 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EMC98905.1 - 2.5e-07 30.9 2.9 2.5e-07 30.9 2.9 3.4 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 EMC98905.1 - 9.3e-07 29.0 1.5 9.3e-07 29.0 1.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain PHD_2 PF13831.6 EMC98905.1 - 1.7e-05 24.2 4.2 3.8e-05 23.2 4.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.25 EMC98905.1 - 2.3e-05 24.2 2.2 2.3e-05 24.2 2.2 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC98905.1 - 3.4e-05 23.6 2.3 3.4e-05 23.6 2.3 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC98905.1 - 0.00011 22.1 1.2 0.00011 22.1 1.2 2.7 4 0 0 4 4 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EMC98905.1 - 0.00037 20.3 0.4 0.00037 20.3 0.4 3.5 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMC98905.1 - 0.00043 20.1 2.0 0.00043 20.1 2.0 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EMC98905.1 - 0.0092 16.0 0.3 0.0092 16.0 0.3 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-PHD-like PF15446.6 EMC98905.1 - 1.1 8.9 5.8 0.24 11.0 1.7 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.6 EMC98905.1 - 2.1 8.5 9.8 0.19 11.8 1.5 3.4 4 1 1 5 5 4 0 RING-type zinc-finger PHF5 PF03660.14 EMC98905.1 - 2.1 8.6 6.5 1.8 8.8 0.7 2.8 2 1 1 3 3 3 0 PHF5-like protein DZR PF12773.7 EMC98905.1 - 7 6.8 7.8 1.3 9.1 1.0 2.9 2 1 2 4 4 3 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EMC98905.1 - 9.3 6.0 14.7 0.39 10.4 1.5 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Ribosomal_L37ae PF01780.19 EMC98906.1 - 8.4e-42 141.2 9.9 9.4e-42 141.0 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-BED PF02892.15 EMC98906.1 - 0.0068 16.4 7.6 0.32 11.1 1.3 2.2 1 1 1 2 2 2 2 BED zinc finger zf-RING_13 PF17977.1 EMC98906.1 - 0.0096 16.0 3.1 0.014 15.6 3.1 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Elf1 PF05129.13 EMC98906.1 - 0.013 15.5 1.9 0.019 15.0 1.9 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 EMC98906.1 - 0.023 14.6 2.1 0.034 14.1 2.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C1_2 PF03107.16 EMC98906.1 - 0.029 14.7 2.6 0.91 9.9 0.1 2.1 1 1 1 2 2 2 0 C1 domain zinc_ribbon_2 PF13240.6 EMC98906.1 - 0.034 13.8 1.9 5 7.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 EMC98906.1 - 0.043 13.8 4.6 0.075 13.0 4.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF2175 PF09943.9 EMC98906.1 - 0.075 13.3 0.9 3 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-H2C2_2 PF13465.6 EMC98906.1 - 0.079 13.4 4.8 0.83 10.2 1.4 2.3 1 1 1 2 2 2 0 Zinc-finger double domain zf-IS66 PF13005.7 EMC98906.1 - 0.088 13.2 3.9 3.6 8.1 0.1 2.4 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF1451 PF07295.11 EMC98906.1 - 0.096 12.7 1.2 0.13 12.3 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 EMC98906.1 - 0.11 12.6 1.4 0.28 11.3 1.4 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2HC5 PF06221.13 EMC98906.1 - 0.14 12.2 2.4 0.46 10.5 2.4 1.7 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type HalOD2 PF18547.1 EMC98906.1 - 0.18 11.7 5.6 1.8 8.5 1.1 2.4 1 1 1 2 2 2 0 Halobacterial output domain 2 Desulfoferrod_N PF06397.12 EMC98906.1 - 0.77 9.4 4.1 2.5 7.8 0.5 2.2 1 1 1 2 2 2 0 Desulfoferrodoxin, N-terminal domain Zn_ribbon_SprT PF17283.2 EMC98906.1 - 2.7 8.0 10.0 0.1 12.5 3.9 1.8 2 0 0 2 2 1 0 SprT-like zinc ribbon domain Sacchrp_dh_NADP PF03435.18 EMC98907.1 - 7.8e-15 55.3 0.0 1.2e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AMP-binding PF00501.28 EMC98908.1 - 1.4e-74 251.2 0.0 1.8e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC98908.1 - 2.5e-14 54.0 0.0 9.5e-14 52.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PHF5 PF03660.14 EMC98909.1 - 1.3e-51 173.1 10.4 1.5e-51 173.0 10.4 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EMC98909.1 - 0.17 9.7 5.9 0.035 12.0 2.9 1.2 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EMC98909.1 - 2.7 8.1 15.5 6 7.0 2.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 EMC98910.1 - 4.8e-73 245.8 0.0 6.3e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC98910.1 - 1.3e-37 129.5 0.0 1.8e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC98910.1 - 0.00015 21.2 0.0 0.00033 20.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like bZIP_C PF12498.8 EMC98910.1 - 0.42 11.6 3.4 0.94 10.5 3.4 1.5 1 0 0 1 1 1 0 Basic leucine-zipper C terminal Kinesin PF00225.23 EMC98913.1 - 3e-85 286.1 0.5 5.9e-47 160.2 2.3 2.4 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EMC98913.1 - 6.8e-48 162.4 0.0 1.8e-47 161.0 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding ADIP PF11559.8 EMC98913.1 - 0.00045 20.3 6.7 0.00045 20.3 6.7 3.7 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding Abi_C PF14355.6 EMC98913.1 - 0.029 14.5 0.1 0.11 12.6 0.1 2.0 1 0 0 1 1 1 0 Abortive infection C-terminus ApoO PF09769.9 EMC98913.1 - 0.077 13.0 5.0 1 9.3 0.1 2.8 2 0 0 2 2 2 0 Apolipoprotein O CtIP_N PF10482.9 EMC98913.1 - 0.21 11.6 20.4 0.027 14.5 7.2 3.5 2 2 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Prefoldin PF02996.17 EMC98913.1 - 0.26 11.2 0.1 0.26 11.2 0.1 4.2 4 0 0 4 4 4 0 Prefoldin subunit TSC22 PF01166.18 EMC98913.1 - 0.31 11.4 4.8 1.8 8.9 0.5 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family Fez1 PF06818.15 EMC98913.1 - 2.2 8.7 36.0 2 8.8 19.5 2.6 1 1 0 2 2 2 0 Fez1 KLRAQ PF10205.9 EMC98913.1 - 7.1 6.9 18.7 0.031 14.5 3.9 3.7 2 2 2 4 4 4 0 Predicted coiled-coil domain-containing protein DUF4472 PF14739.6 EMC98913.1 - 9.6 7.0 27.0 0.15 12.8 3.8 3.8 2 1 1 4 4 3 0 Domain of unknown function (DUF4472) Acyltransferase PF01553.21 EMC98914.1 - 9.8e-07 28.5 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ank_2 PF12796.7 EMC98915.1 - 2.6e-34 117.7 7.0 4.1e-11 43.3 0.0 8.4 7 1 1 8 8 8 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC98915.1 - 1.2e-27 95.8 6.8 4.4e-09 36.7 0.1 9.6 8 2 2 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 EMC98915.1 - 1e-26 92.1 9.8 1.6e-05 25.1 0.1 7.7 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EMC98915.1 - 5.9e-25 84.6 9.3 0.00012 22.3 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EMC98915.1 - 2.3e-22 78.7 18.8 6.2e-06 26.4 0.3 8.8 10 0 0 10 10 10 4 Ankyrin repeats (many copies) FbpA PF05833.11 EMC98915.1 - 0.11 11.3 3.2 0.22 10.3 3.2 1.4 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Terminase_3 PF04466.13 EMC98915.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Phage terminase large subunit UPF0242 PF06785.11 EMC98915.1 - 0.34 11.0 5.0 0.98 9.5 5.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SRP_TPR_like PF17004.5 EMC98916.1 - 1.3e-16 60.7 0.8 2.8e-16 59.6 0.8 1.6 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 EMC98916.1 - 8.1e-16 58.2 10.0 8.1e-16 58.2 10.0 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 EMC98916.1 - 7.1e-05 23.0 9.4 0.46 10.7 0.6 5.4 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EMC98916.1 - 0.00039 20.9 21.5 0.18 12.3 0.0 6.2 4 1 2 6 6 6 2 Tetratricopeptide repeat DUF410 PF04190.13 EMC98916.1 - 0.001 18.9 0.2 0.062 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF410) TPR_17 PF13431.6 EMC98916.1 - 0.026 14.9 0.8 3 8.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMC98916.1 - 0.1 12.4 1.6 0.86 9.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EMC98916.1 - 0.79 9.9 0.0 0.79 9.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMC98916.1 - 0.87 10.6 31.4 7.4 7.7 0.2 8.6 8 3 3 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMC98916.1 - 7.2 7.5 7.3 1.1e+02 3.8 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat GST_C PF00043.25 EMC98917.1 - 3.3e-10 40.0 0.0 7.7e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMC98917.1 - 3.8e-07 30.0 0.0 7.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMC98917.1 - 2e-05 24.7 0.0 6.2e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PRCC PF10253.9 EMC98918.1 - 3.5e-27 96.6 15.0 1.8e-25 91.0 15.0 2.3 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting LZ_Tnp_IS66 PF13007.7 EMC98918.1 - 1.2 10.0 0.1 1.2 10.0 0.1 2.9 3 1 0 3 3 3 0 Transposase C of IS166 homeodomain Acetyltransf_3 PF13302.7 EMC98919.1 - 1.8e-14 54.6 0.0 2.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC98919.1 - 1.1e-11 45.0 0.0 1.6e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EMC98919.1 - 6.2e-06 26.6 0.0 9.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EMC98919.1 - 0.00016 21.8 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMC98919.1 - 0.0023 17.9 0.1 0.0075 16.2 0.0 1.9 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 EMC98919.1 - 0.0084 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EMC98919.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arrestin_N PF00339.29 EMC98920.1 - 6.7e-13 48.9 0.1 2.2e-11 44.0 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EMC98920.1 - 0.0011 18.4 0.0 0.0038 16.7 0.0 1.7 1 1 1 2 2 2 1 Bul1 C terminus TFIIA PF03153.13 EMC98921.1 - 8.1e-79 266.5 21.4 1.8e-78 265.4 21.4 1.5 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MalF_P2 PF14785.6 EMC98921.1 - 0.0095 16.0 1.7 0.019 15.0 1.7 1.4 1 0 0 1 1 1 1 Maltose transport system permease protein MalF P2 domain DUF2237 PF09996.9 EMC98922.1 - 5.2e-42 142.5 0.0 6.1e-42 142.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) p450 PF00067.22 EMC98923.1 - 2.7e-60 204.5 0.0 3.6e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B_3 PF13483.6 EMC98924.1 - 1.2e-05 25.3 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EMC98924.1 - 0.012 15.1 3.2 0.059 12.9 0.1 2.9 3 0 0 3 3 3 0 Beta-lactamase superfamily domain SPRY PF00622.28 EMC98925.1 - 2.6e-05 24.3 0.0 5.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SPRY domain zf-RING_2 PF13639.6 EMC98926.1 - 6.6e-09 36.0 5.4 1.5e-08 34.8 5.4 1.6 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EMC98926.1 - 8.6e-08 32.4 2.8 1.5e-07 31.5 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EMC98926.1 - 5.3e-06 26.1 3.2 0.0017 18.0 0.7 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 EMC98926.1 - 7.3e-06 26.0 0.8 1.8e-05 24.7 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EMC98926.1 - 8.9e-06 25.5 3.0 1.5e-05 24.7 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC98926.1 - 6.9e-05 22.7 2.4 0.00013 21.9 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMC98926.1 - 8.9e-05 22.3 8.0 0.0013 18.6 8.0 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC98926.1 - 0.00032 20.7 1.9 0.00042 20.3 1.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger LapA_dom PF06305.11 EMC98926.1 - 0.01 15.6 0.5 0.022 14.6 0.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MASE1 PF05231.14 EMC98926.1 - 0.039 13.1 0.4 0.06 12.5 0.4 1.2 1 0 0 1 1 1 0 MASE1 Prok-RING_4 PF14447.6 EMC98926.1 - 0.045 13.6 6.3 0.099 12.5 6.2 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 EMC98926.1 - 0.071 13.4 1.7 0.18 12.2 1.7 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 EMC98926.1 - 0.086 12.7 4.8 0.25 11.3 4.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EMC98926.1 - 0.24 11.0 1.0 0.51 10.0 1.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 EMC98926.1 - 0.28 11.2 2.9 0.68 10.0 2.9 1.6 1 0 0 1 1 1 0 Zinc-finger PHD_4 PF16866.5 EMC98926.1 - 0.48 10.6 2.2 1.2 9.2 2.2 1.6 1 1 0 1 1 1 0 PHD-finger PHD PF00628.29 EMC98926.1 - 0.53 10.2 2.9 1 9.3 2.9 1.5 1 0 0 1 1 1 0 PHD-finger C1_4 PF07975.12 EMC98926.1 - 0.6 10.4 2.4 1 9.7 2.4 1.4 1 0 0 1 1 1 0 TFIIH C1-like domain Ada3 PF10198.9 EMC98927.1 - 7.4e-44 149.1 0.7 7.4e-44 149.1 0.7 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF1770 PF08589.10 EMC98927.1 - 0.57 11.2 5.1 2.6 9.1 0.3 2.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) MFS_1 PF07690.16 EMC98928.1 - 5.1e-37 127.6 25.9 9.8e-37 126.7 25.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 EMC98928.1 - 8.9 5.9 10.2 13 5.3 0.0 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Cellulase PF00150.18 EMC98930.1 - 8.7e-17 61.4 1.0 8.7e-17 61.4 1.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Ku_PK_bind PF08785.11 EMC98930.1 - 0.0079 16.3 0.0 0.03 14.5 0.0 1.8 1 1 1 2 2 2 1 Ku C terminal domain like zinc_ribbon_15 PF17032.5 EMC98931.1 - 0.00014 22.5 0.5 0.00023 21.8 0.5 1.4 1 0 0 1 1 1 1 zinc-ribbon family Lar_restr_allev PF14354.6 EMC98931.1 - 0.056 13.8 2.3 8 6.9 2.3 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar RecR PF02132.15 EMC98931.1 - 0.14 11.8 1.7 1 9.0 0.1 2.2 2 0 0 2 2 2 0 RecR protein PHD_3 PF13922.6 EMC98931.1 - 0.19 12.1 3.0 6.5 7.2 0.2 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-LITAF-like PF10601.9 EMC98931.1 - 0.32 11.3 0.2 0.32 11.3 0.2 2.3 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain TEA PF01285.18 EMC98932.1 - 3.4e-29 100.7 0.3 4.4e-29 100.4 0.3 1.1 1 0 0 1 1 1 1 TEA/ATTS domain dsrm PF00035.26 EMC98934.1 - 6.3e-06 26.8 2.2 0.29 11.9 0.0 3.6 3 1 0 3 3 3 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 EMC98934.1 - 0.005 17.0 0.1 2.4 8.4 0.0 2.7 2 0 0 2 2 2 2 Dicer dimerisation domain Amidohydro_1 PF01979.20 EMC98935.1 - 1.1e-73 248.5 0.2 1.8e-73 247.9 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EMC98935.1 - 4.5e-54 181.9 1.3 1e-53 180.8 1.3 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EMC98935.1 - 3.5e-40 136.0 0.1 8.1e-40 134.8 0.1 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 EMC98935.1 - 6.9e-39 132.2 0.1 1.9e-38 130.7 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit HMG_box PF00505.19 EMC98935.1 - 5.9e-11 42.6 0.8 1.3e-10 41.5 0.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Amidohydro_3 PF07969.11 EMC98935.1 - 3.8e-10 39.8 0.1 5e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family HMG_box_2 PF09011.10 EMC98935.1 - 1.6e-06 28.6 1.3 3.3e-06 27.6 1.3 1.6 1 0 0 1 1 1 1 HMG-box domain Nop14 PF04147.12 EMC98935.1 - 0.0045 15.3 28.4 0.0067 14.7 28.4 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EMC98935.1 - 0.0061 16.0 25.9 0.011 15.2 25.9 1.4 1 0 0 1 1 1 1 SDA1 PPP4R2 PF09184.11 EMC98935.1 - 10 5.6 25.7 23 4.5 25.7 1.6 1 0 0 1 1 1 0 PPP4R2 Pro_isomerase PF00160.21 EMC98936.1 - 7.5e-36 123.8 0.0 1.2e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EMC98936.1 - 4e-16 58.6 0.0 7.4e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 EMC98938.1 - 8.8e-06 25.7 6.8 1.6e-05 25.0 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF155 PF02582.14 EMC98939.1 - 2.1e-53 181.0 0.0 3.5e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SecG PF03840.14 EMC98939.1 - 0.19 11.8 1.7 2.4 8.3 1.1 2.3 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Bromodomain PF00439.25 EMC98940.1 - 2.4e-22 78.8 0.0 4.1e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EMC98940.1 - 1.6e-09 38.0 0.0 2.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC98940.1 - 4e-07 30.0 0.3 9.3e-07 28.8 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC98940.1 - 3.9e-05 24.0 0.0 6.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ost5 PF05251.12 EMC98941.1 - 1.6e-20 73.2 7.1 1.8e-20 72.9 7.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Rad1 PF02144.16 EMC98942.1 - 5.9e-74 248.6 0.0 6.7e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 GST_C PF00043.25 EMC98943.1 - 3.8e-08 33.4 0.0 5.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EMC98943.1 - 1.8e-05 25.0 0.0 3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMC98943.1 - 7.5e-05 23.1 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMC98943.1 - 0.00035 20.7 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMC98943.1 - 0.00042 20.3 0.0 0.00085 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EMC98943.1 - 0.00044 20.5 0.0 0.00076 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EMC98943.1 - 0.052 14.1 0.0 0.096 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M16 PF00675.20 EMC98944.1 - 2.8e-57 192.9 1.3 5.1e-57 192.0 0.3 2.0 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EMC98944.1 - 1.7e-36 125.9 0.0 5.1e-36 124.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.12 EMC98945.1 - 1.1e-42 144.9 0.0 1.3e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit EMP70 PF02990.16 EMC98946.1 - 3.6e-191 636.4 0.1 4.4e-191 636.1 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ParB_C PF18064.1 EMC98947.1 - 0.007 16.5 0.3 0.038 14.2 0.0 2.4 2 0 0 2 2 2 1 Centromere-binding protein ParB C-terminal zf-C3HC4_3 PF13920.6 EMC98948.1 - 0.00041 20.2 9.9 0.00061 19.6 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EMC98948.1 - 0.02 15.0 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.6 EMC98948.1 - 3 7.8 7.8 5.4 7.0 7.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Abhydrolase_3 PF07859.13 EMC98949.1 - 1.6e-24 86.9 0.0 2.3e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMC98949.1 - 6.6e-21 74.6 0.0 1.1e-20 73.8 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EMC98949.1 - 0.065 12.1 0.1 2.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family adh_short PF00106.25 EMC98950.1 - 2.8e-25 88.9 0.0 3.6e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC98950.1 - 6.6e-18 65.1 0.0 8.3e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC98950.1 - 9.5e-06 25.6 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 KR domain UPF0113_N PF17833.1 EMC98951.1 - 4.3e-27 94.5 0.0 5.7e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EMC98951.1 - 4.9e-25 87.6 0.0 8.5e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain NOC3p PF07540.11 EMC98952.1 - 1.6e-30 105.4 2.5 8.4e-30 103.1 0.0 3.3 3 1 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 EMC98952.1 - 2.2e-23 83.1 2.0 2.4e-23 83.0 0.2 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Nsp1_C PF05064.13 EMC98953.1 - 1.7e-32 111.7 0.0 4.5e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EMC98953.1 - 2e-27 95.9 198.5 1.5e-09 38.5 34.6 7.7 1 1 6 7 7 7 4 Nucleoporin FG repeat region Exonuc_VII_L PF02601.15 EMC98953.1 - 0.055 13.0 0.2 0.2 11.2 0.1 1.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit Dynamitin PF04912.14 EMC98953.1 - 0.29 10.4 2.9 0.19 11.0 0.3 1.9 2 1 0 2 2 2 0 Dynamitin CK2S PF15011.6 EMC98953.1 - 0.79 9.6 2.5 0.76 9.7 0.7 1.8 2 0 0 2 2 2 0 Casein Kinase 2 substrate APG6_N PF17675.1 EMC98953.1 - 0.92 10.0 3.8 4.4 7.8 0.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 EMC98954.1 - 0.0019 18.4 4.0 0.0019 18.4 4.0 3.1 1 1 3 4 4 4 1 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.11 EMC98954.1 - 0.3 10.9 5.7 1 9.2 0.2 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 EMC98954.1 - 0.54 10.3 40.6 0.047 13.7 14.5 3.4 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 EMC98954.1 - 0.59 10.3 14.3 0.051 13.7 1.2 3.7 3 0 0 3 3 3 0 bZIP transcription factor Fungal_trans_2 PF11951.8 EMC98954.1 - 0.61 8.8 7.4 0.049 12.4 2.1 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain GAS PF13851.6 EMC98954.1 - 2.9 7.2 31.3 0.75 9.1 17.0 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Lectin_N PF03954.14 EMC98954.1 - 4.2 7.1 9.0 3.5 7.4 2.1 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 EMC98954.1 - 6.8 7.2 9.0 0.58 10.7 1.5 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3176 PF11374.8 EMC98955.1 - 7.1e-26 90.5 0.2 2.6e-25 88.7 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) GLTT PF01744.20 EMC98955.1 - 0.23 11.2 3.3 0.74 9.6 0.5 2.6 2 0 0 2 2 2 0 GLTT repeat (6 copies) NAD_binding_1 PF00175.21 EMC98956.1 - 2.4e-33 115.0 0.0 4.2e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EMC98956.1 - 2.2e-23 82.4 0.0 4.2e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EMC98956.1 - 4e-09 36.8 0.0 0.00012 22.2 0.0 2.5 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EMC98956.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF4366 PF14283.6 EMC98956.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Gram_pos_anchor PF00746.21 EMC98956.1 - 0.12 12.4 0.5 0.29 11.1 0.5 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif FAD-oxidase_C PF02913.19 EMC98957.1 - 8.5e-58 195.9 0.0 1.3e-57 195.3 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EMC98957.1 - 9.5e-37 125.8 0.0 1.6e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Methyltransf_23 PF13489.6 EMC98959.1 - 2.4e-20 73.0 0.0 3.6e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC98959.1 - 1.3e-12 48.3 0.0 7.5e-12 45.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC98959.1 - 5.6e-10 39.7 0.0 1.8e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC98959.1 - 1.6e-09 37.7 0.0 7.7e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC98959.1 - 6e-09 36.5 0.0 1.9e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EMC98959.1 - 0.0028 17.2 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EMC98959.1 - 0.004 16.5 0.0 0.0087 15.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EMC98959.1 - 0.0098 15.4 0.0 0.032 13.7 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.9 EMC98959.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 EMC98959.1 - 0.022 14.1 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 EMC98959.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EMC98959.1 - 0.073 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HATPase_c PF02518.26 EMC98961.1 - 1.1e-23 83.9 0.0 2.2e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMC98961.1 - 4.1e-23 81.7 0.0 9e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 EMC98961.1 - 3.7e-08 33.6 0.0 4.4e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EMC98961.1 - 1.5e-07 31.6 0.0 2.5e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EMC98961.1 - 5.2e-07 29.7 0.0 8.2e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 EMC98961.1 - 8e-07 29.0 2.0 3.6e-06 26.9 0.1 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EMC98961.1 - 0.0003 21.1 0.0 0.0011 19.2 0.0 2.0 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 EMC98961.1 - 0.0042 17.1 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EMC98961.1 - 0.029 14.7 0.1 0.064 13.6 0.1 1.7 1 0 0 1 1 1 0 PAS fold YfcL PF08891.11 EMC98961.1 - 0.061 13.7 0.1 16 5.9 0.0 2.9 2 0 0 2 2 2 0 YfcL protein GAF_3 PF13492.6 EMC98961.1 - 0.073 13.4 0.0 0.43 10.9 0.0 2.4 3 0 0 3 3 3 0 GAF domain Fungal_trans PF04082.18 EMC98962.1 - 8.7e-13 47.9 2.5 1.3e-12 47.4 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC98962.1 - 6.6e-08 32.5 10.5 1.2e-07 31.8 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylsulfotrans PF05935.11 EMC98963.1 - 2e-27 96.1 0.5 3.9e-15 55.6 0.1 2.6 1 1 2 3 3 3 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 EMC98963.1 - 1.8e-18 66.9 0.0 2.9e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 EMC98963.1 - 0.0001 22.0 0.7 0.34 10.4 0.0 3.2 2 1 0 3 3 3 2 PQQ-like domain APS-reductase_C PF12139.8 EMC98963.1 - 0.052 13.8 0.0 0.97 9.7 0.0 2.5 2 0 0 2 2 2 0 Adenosine-5'-phosphosulfate reductase beta subunit SGL PF08450.12 EMC98963.1 - 0.064 12.8 0.0 14 5.2 0.0 2.6 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region PQQ PF01011.21 EMC98963.1 - 2.1 8.4 4.4 18 5.5 0.0 3.8 5 0 0 5 5 5 0 PQQ enzyme repeat MFS_1 PF07690.16 EMC98964.1 - 6.3e-34 117.4 17.8 6.3e-34 117.4 17.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC98964.1 - 3.4e-09 36.1 2.0 3.4e-09 36.1 2.0 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter 7TM-7TMR_HD PF07698.11 EMC98964.1 - 0.014 15.2 0.3 0.014 15.2 0.3 3.6 2 2 1 3 3 3 0 7TM receptor with intracellular HD hydrolase Mei5 PF10376.9 EMC98965.1 - 1.4 8.7 9.6 0.088 12.7 0.3 2.6 2 1 1 3 3 3 0 Double-strand recombination repair protein TFB6 PF17110.5 EMC98966.1 - 6.7e-56 188.7 0.0 8.4e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH DUF3431 PF11913.8 EMC98968.1 - 3.5e-78 262.3 0.7 3.9e-78 262.1 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_transf_28 PF03033.20 EMC98969.1 - 1e-16 61.3 0.1 6e-13 49.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EMC98969.1 - 2.1e-07 30.1 0.0 3.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 EMC98969.1 - 0.00013 22.3 0.0 0.00046 20.5 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 EMC98969.1 - 0.0046 17.0 0.1 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.20 EMC98969.1 - 0.0046 16.8 21.3 0.59 10.2 2.8 4.9 4 0 0 4 4 4 3 Ubiquitin interaction motif Aldedh PF00171.22 EMC98969.1 - 0.099 11.1 0.3 0.18 10.2 0.3 1.4 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Cation_ATPase_C PF00689.21 EMC98971.1 - 1.2 8.9 6.6 0.62 9.8 2.7 2.1 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus FAD_binding_4 PF01565.23 EMC98973.1 - 5.9e-20 71.4 2.5 1e-19 70.6 2.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EMC98973.1 - 2.3e-10 40.4 0.9 7.4e-10 38.8 0.3 2.1 2 0 0 2 2 2 1 Berberine and berberine like SBF PF01758.16 EMC98975.1 - 1.3e-47 162.0 7.4 1.3e-47 162.0 7.4 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family Kinocilin PF15033.6 EMC98975.1 - 0.039 13.6 0.4 0.15 11.7 0.4 2.0 1 0 0 1 1 1 0 Kinocilin protein PIG-P PF08510.12 EMC98975.1 - 2.6 8.0 6.5 9.9 6.1 0.6 2.9 2 1 0 2 2 2 0 PIG-P PTR2 PF00854.21 EMC98976.1 - 6.3e-65 219.5 5.2 8.7e-65 219.1 5.2 1.1 1 0 0 1 1 1 1 POT family CcmH PF03918.14 EMC98976.1 - 0.018 14.4 0.2 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein TssN PF17555.2 EMC98976.1 - 2.3 7.5 10.9 0.42 10.0 1.2 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF676 PF05057.14 EMC98978.1 - 5.5e-47 160.1 0.0 8.2e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EMC98978.1 - 2.6e-05 24.2 0.0 3.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EMC98978.1 - 0.00018 21.4 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 EMC98978.1 - 0.038 13.5 0.0 0.26 10.8 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EMC98978.1 - 0.048 14.3 0.0 0.096 13.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Macoilin PF09726.9 EMC98979.1 - 0.17 10.4 0.6 0.25 9.8 0.6 1.2 1 0 0 1 1 1 0 Macoilin family MmgE_PrpD PF03972.14 EMC98981.1 - 1.7e-114 382.8 4.5 2e-114 382.6 4.5 1.0 1 0 0 1 1 1 1 MmgE/PrpD family OmpA_membrane PF01389.17 EMC98981.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 OmpA-like transmembrane domain DUF5102 PF17104.5 EMC98984.1 - 1.1e-92 311.2 0.1 1.6e-92 310.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) AAA_PrkA PF08298.11 EMC98984.1 - 0.05 12.5 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain Clathrin_bdg PF15045.6 EMC98984.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking FAM220 PF15487.6 EMC98984.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 FAM220 family 14-3-3 PF00244.20 EMC98987.1 - 1.9e-105 351.3 8.1 2.2e-105 351.1 8.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1539 PF07560.11 EMC98987.1 - 0.026 14.6 0.8 0.089 12.9 0.2 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) TPR_12 PF13424.6 EMC98987.1 - 0.05 13.9 1.2 6.8 7.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TerB PF05099.13 EMC98987.1 - 0.053 13.5 1.7 0.055 13.4 0.2 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TerB DUF3802 PF12290.8 EMC98987.1 - 0.084 13.4 0.7 3.9 8.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) Orbi_VP5 PF00901.17 EMC98987.1 - 0.086 11.2 4.1 0.18 10.2 4.2 1.4 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 DUF4253 PF14062.6 EMC98987.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) TPR_19 PF14559.6 EMC98987.1 - 0.49 10.9 3.5 1.7 9.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 EMC98988.1 - 6.2e-45 150.9 0.0 1.5e-16 60.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC98988.1 - 8.5e-06 25.5 0.0 0.056 13.3 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EMC98988.1 - 1e-05 25.5 0.0 0.0019 18.2 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 EMC98988.1 - 5.6e-05 23.1 0.0 0.0024 17.8 0.1 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EMC98988.1 - 0.00024 21.2 0.3 0.057 13.5 0.0 3.3 3 1 0 3 3 3 1 RNA recognition motif PHM7_cyt PF14703.6 EMC98988.1 - 0.019 15.2 0.1 2.7 8.2 0.0 3.2 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 EMC98988.1 - 0.036 13.7 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EMC98988.1 - 0.04 13.6 0.2 9.8 6.0 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RNA_pol_Rpb2_6 PF00562.28 EMC98989.1 - 8.9e-125 416.8 0.0 1.3e-124 416.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EMC98989.1 - 4.7e-57 192.8 0.0 8.6e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EMC98989.1 - 2.6e-42 144.6 0.1 5.2e-42 143.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EMC98989.1 - 1e-31 109.2 0.1 2.3e-31 108.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EMC98989.1 - 4.8e-26 90.7 0.1 1.1e-25 89.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EMC98989.1 - 2.9e-22 79.0 1.3 8.6e-22 77.5 1.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 EMC98989.1 - 2e-21 76.0 0.2 6.3e-21 74.4 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 ADH_N PF08240.12 EMC98990.1 - 1e-07 31.8 0.0 2.8e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PPO1_DWL PF12142.8 EMC98990.1 - 0.0085 15.9 0.0 0.45 10.3 0.0 2.5 2 0 0 2 2 2 1 Polyphenol oxidase middle domain ADH_zinc_N PF00107.26 EMC98990.1 - 0.029 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CsbD PF05532.12 EMC98991.1 - 1.4 8.8 6.8 0.21 11.5 2.7 1.7 2 0 0 2 2 2 0 CsbD-like BAR PF03114.18 EMC98992.1 - 4.3e-59 200.1 9.2 5.5e-59 199.7 9.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EMC98992.1 - 2.2e-13 49.6 0.1 3.9e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMC98992.1 - 5.3e-11 42.2 0.1 9.3e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMC98992.1 - 5.8e-07 29.1 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BRE1 PF08647.11 EMC98992.1 - 2.1 8.5 12.3 2.4 8.3 0.3 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4375 PF14300.6 EMC98992.1 - 2.7 8.3 7.1 0.66 10.3 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) PIN_12 PF16289.5 EMC98992.1 - 6.3 7.3 9.8 3.9 7.9 5.2 2.2 2 0 0 2 2 2 0 PIN domain Asp PF00026.23 EMC98993.1 - 9.2e-11 41.7 0.1 1.3e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Rax2 PF12768.7 EMC98993.1 - 0.0017 17.8 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TAXi_N PF14543.6 EMC98993.1 - 0.0067 16.7 0.3 0.044 14.0 0.3 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF4381 PF14316.6 EMC98993.1 - 0.0084 16.4 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Phage_holin_2_4 PF16082.5 EMC98993.1 - 0.044 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like VSP PF03302.13 EMC98993.1 - 0.055 12.3 1.4 0.081 11.8 1.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 EMC98993.1 - 0.072 12.5 9.1 0.14 11.6 9.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PepSY_TM PF03929.16 EMC98993.1 - 0.079 12.6 0.9 0.14 11.8 0.2 1.6 2 0 0 2 2 2 0 PepSY-associated TM region DUF202 PF02656.15 EMC98993.1 - 0.096 13.1 0.2 0.21 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PTP_tm PF18861.1 EMC98993.1 - 0.11 12.5 1.6 0.21 11.5 1.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Myosin_tail_1 PF01576.19 EMC98994.1 - 0.05 11.4 0.2 0.078 10.8 0.2 1.2 1 0 0 1 1 1 0 Myosin tail PspA_IM30 PF04012.12 EMC98994.1 - 0.071 12.7 0.1 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 PspA/IM30 family TolA_bind_tri PF16331.5 EMC98994.1 - 0.091 12.8 6.8 1.6 8.8 2.4 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation KLRAQ PF10205.9 EMC98994.1 - 0.12 12.6 1.2 0.27 11.5 0.3 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein EzrA PF06160.12 EMC98994.1 - 0.18 10.0 0.1 0.29 9.3 0.1 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_11 PF13086.6 EMC98995.1 - 2e-59 201.5 0.0 5.1e-59 200.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EMC98995.1 - 1.1e-55 188.4 0.0 3.6e-55 186.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMC98995.1 - 1.1e-12 48.0 0.0 6.6e-11 42.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EMC98995.1 - 2.5e-10 40.9 0.0 2.5e-09 37.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EMC98995.1 - 4.7e-07 29.4 0.0 0.0081 15.4 0.1 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EMC98995.1 - 1.3e-05 24.9 0.0 0.0015 18.1 0.0 2.4 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 EMC98995.1 - 2e-05 24.5 0.0 1.6 8.4 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EMC98995.1 - 7.2e-05 22.8 0.0 0.00038 20.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EMC98995.1 - 0.00024 20.6 0.0 0.063 12.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 EMC98995.1 - 0.00027 21.2 0.1 0.0016 18.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EMC98995.1 - 0.0046 16.9 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SSE PF00437.20 EMC98995.1 - 0.0048 16.0 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C PF13361.6 EMC98995.1 - 0.0061 16.0 0.0 3.7 6.8 0.0 3.0 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 EMC98995.1 - 0.0096 16.3 0.1 0.027 14.9 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 EMC98995.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 EMC98995.1 - 0.014 15.0 0.1 0.16 11.5 0.0 2.6 1 1 1 3 3 3 0 AAA domain Helicase_RecD PF05127.14 EMC98995.1 - 0.028 14.3 0.0 0.45 10.4 0.0 2.5 1 1 0 1 1 1 0 Helicase AAA PF00004.29 EMC98995.1 - 0.032 14.6 0.1 0.23 11.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EMC98995.1 - 0.046 13.4 0.0 0.26 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 EMC98995.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain PCB_OB PF17092.5 EMC98995.1 - 0.082 13.7 0.3 0.31 11.8 0.3 2.0 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain PIF1 PF05970.14 EMC98995.1 - 0.11 11.6 0.0 7.4 5.6 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Mg_chelatase PF01078.21 EMC98995.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI F-box-like_2 PF13013.6 EMC98996.1 - 0.031 14.3 0.6 0.075 13.0 0.1 2.0 2 1 0 2 2 2 0 F-box-like domain PIG-F PF06699.11 EMC98997.1 - 8.9e-66 221.5 8.1 1e-65 221.3 8.1 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_Omp PF13488.6 EMC98997.1 - 0.034 14.1 4.3 0.11 12.5 4.3 1.7 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 EMC98997.1 - 0.067 12.9 3.3 2.2 8.1 0.6 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Romo1 PF10247.9 EMC98997.1 - 0.4 11.1 3.3 15 6.1 0.1 2.6 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Laminin_G_1 PF00054.23 EMC98998.1 - 0.038 14.2 0.7 0.26 11.5 0.0 2.4 2 0 0 2 2 2 0 Laminin G domain RhoGAP PF00620.27 EMC99001.1 - 9.2e-39 132.7 0.0 1.2e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain mRNA_decap_C PF16741.5 EMC99001.1 - 0.074 12.4 0.2 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus zf-Tim10_DDP PF02953.15 EMC99003.1 - 5.9e-20 70.7 6.4 8.4e-20 70.2 6.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tam41_Mmp37 PF09139.11 EMC99003.1 - 0.028 13.8 0.2 0.033 13.6 0.2 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial DUF842 PF05811.13 EMC99003.1 - 0.052 13.3 7.5 1.4 8.6 1.0 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) PAH PF02671.21 EMC99003.1 - 0.088 13.0 0.0 0.19 11.9 0.0 1.7 1 1 0 1 1 1 0 Paired amphipathic helix repeat Translin PF01997.16 EMC99004.1 - 3.1e-48 164.5 0.0 3.5e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Translin family FAA_hydro_N_2 PF18288.1 EMC99004.1 - 0.061 13.8 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 LPP20 PF02169.16 EMC99004.1 - 0.069 13.5 0.5 0.14 12.5 0.5 1.5 1 0 0 1 1 1 0 LPP20 lipoprotein GMP_synt_C PF00958.22 EMC99004.1 - 0.12 12.4 0.0 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 GMP synthase C terminal domain NmrA PF05368.13 EMC99005.1 - 6.9e-07 29.1 0.0 0.00052 19.6 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EMC99005.1 - 3.2e-06 27.2 0.0 6e-06 26.3 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding VirC2 PF07181.11 EMC99005.1 - 0.09 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 VirC2 protein Shikimate_DH PF01488.20 EMC99005.1 - 0.17 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Homeodomain PF00046.29 EMC99007.1 - 1e-13 50.9 1.4 1.8e-13 50.1 1.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EMC99007.1 - 0.085 12.8 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain Amino_oxidase PF01593.24 EMC99008.1 - 2.9e-48 165.3 0.1 1.5e-47 162.9 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMC99008.1 - 1.5e-15 57.2 0.1 3.2e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMC99008.1 - 3.4e-06 27.5 0.0 6.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC99008.1 - 8.1e-06 25.3 0.1 2.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC99008.1 - 8.3e-06 25.6 0.1 2.6e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMC99008.1 - 0.00015 21.8 0.5 0.0082 16.1 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EMC99008.1 - 0.00051 18.9 0.0 0.00072 18.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EMC99008.1 - 0.001 18.2 0.4 0.002 17.3 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EMC99008.1 - 0.0017 17.7 0.3 0.0032 16.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EMC99008.1 - 0.0065 15.9 0.0 0.0096 15.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EMC99008.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EMC99008.1 - 0.026 14.4 0.3 0.067 13.1 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMC99008.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EMC99008.1 - 0.27 10.9 0.4 0.53 9.9 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 EMC99008.1 - 0.27 10.3 0.4 0.4 9.7 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RFX_DNA_binding PF02257.15 EMC99009.1 - 4.1e-05 24.1 0.1 0.13 12.9 0.0 2.5 2 0 0 2 2 2 2 RFX DNA-binding domain COPIIcoated_ERV PF07970.12 EMC99010.1 - 1.1e-36 126.8 0.2 1.6e-36 126.2 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EMC99010.1 - 1.8e-26 92.3 0.0 2.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PS_Dcarbxylase PF02666.15 EMC99012.1 - 3.5e-55 186.7 0.0 5.5e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EMC99012.1 - 1e-43 147.8 0.2 7.8e-22 77.5 0.0 2.8 3 0 0 3 3 3 2 C2 domain GST_N_4 PF17172.4 EMC99012.1 - 1.1e-19 71.0 0.1 3.2e-19 69.5 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EMC99012.1 - 1.7e-14 53.3 0.1 3.4e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EMC99012.1 - 2.2e-11 44.1 0.2 1.1e-10 41.9 0.2 2.2 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 EMC99012.1 - 0.00044 20.5 0.1 0.0013 19.0 0.0 1.9 2 0 0 2 2 2 1 SAM35, subunit of SAM coomplex EF-hand_1 PF00036.32 EMC99012.1 - 0.0016 17.9 0.0 0.005 16.3 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EMC99012.1 - 0.036 14.0 0.0 0.13 12.3 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 EMC99012.1 - 0.071 12.6 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 EF hand Syntaxin PF00804.25 EMC99013.1 - 5.7e-19 68.6 8.3 5.7e-19 68.6 8.3 1.6 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 EMC99013.1 - 1.4e-09 37.8 0.6 3.7e-09 36.4 0.6 1.8 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 EMC99013.1 - 0.0019 17.9 1.7 0.0049 16.6 1.7 1.7 1 0 0 1 1 1 1 Synaptobrevin DotU PF09850.9 EMC99013.1 - 0.032 13.9 1.8 0.034 13.9 0.2 1.8 2 0 0 2 2 2 0 Type VI secretion system protein DotU Mod_r PF07200.13 EMC99013.1 - 0.05 13.7 13.2 0.16 12.1 6.3 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2207 PF09972.9 EMC99013.1 - 0.05 12.4 2.7 0.057 12.2 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 EMC99013.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Vac_Fusion PF02346.16 EMC99013.1 - 0.12 12.0 0.6 0.45 10.2 0.3 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 MCU PF04678.13 EMC99013.1 - 0.37 10.9 8.0 1.4 9.0 3.6 2.5 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Prominin PF05478.11 EMC99013.1 - 0.41 8.5 8.0 2.6 5.9 8.0 1.9 1 1 0 1 1 1 0 Prominin DUF2951 PF11166.8 EMC99013.1 - 0.77 10.0 4.9 0.14 12.4 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Allexi_40kDa PF05549.11 EMC99013.1 - 1.1 8.8 9.3 0.12 11.8 2.7 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein AAA_5 PF07728.14 EMC99014.1 - 2.6e-125 412.9 0.8 1.3e-22 80.3 0.0 10.2 10 0 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EMC99014.1 - 4.9e-46 155.3 6.0 3.6e-16 59.3 0.0 5.5 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_3 PF07726.11 EMC99014.1 - 1.1e-29 103.0 0.0 2.4e-07 30.7 0.0 8.5 9 0 0 9 9 8 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EMC99014.1 - 1.5e-28 99.5 5.0 9.6e-05 22.0 0.0 6.9 6 0 0 6 6 6 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 EMC99014.1 - 3.3e-28 97.8 0.0 2.5e-27 95.0 0.0 2.6 3 0 0 3 3 1 1 Midasin AAA lid domain AAA PF00004.29 EMC99014.1 - 5.9e-26 91.5 0.5 0.004 17.6 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 EMC99014.1 - 1.6e-24 86.3 0.0 0.0022 18.1 0.0 9.0 9 0 0 9 9 9 4 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 EMC99014.1 - 1.4e-23 84.1 24.2 2.6e-05 24.7 0.6 9.6 8 1 0 8 8 6 6 AAA ATPase domain Sigma54_activat PF00158.26 EMC99014.1 - 4.1e-20 72.2 1.2 0.013 15.2 0.0 7.2 7 0 0 7 7 7 4 Sigma-54 interaction domain AAA_22 PF13401.6 EMC99014.1 - 1.2e-18 67.6 0.9 0.019 15.2 0.0 7.5 6 0 0 6 6 6 3 AAA domain AAA_33 PF13671.6 EMC99014.1 - 2.4e-17 63.5 0.7 0.031 14.4 0.0 7.6 6 1 0 6 6 6 4 AAA domain Sigma54_activ_2 PF14532.6 EMC99014.1 - 3.6e-15 56.3 0.2 0.029 14.5 0.0 6.3 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_18 PF13238.6 EMC99014.1 - 4.1e-15 56.5 2.9 0.67 10.5 0.0 7.4 7 0 0 7 7 6 3 AAA domain AAA_6 PF12774.7 EMC99014.1 - 3.6e-14 52.5 2.5 0.13 11.2 0.0 8.1 9 0 0 9 9 8 3 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 EMC99014.1 - 5.1e-14 52.3 8.3 0.061 13.3 0.0 6.6 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EMC99014.1 - 1.4e-12 47.9 1.8 0.14 12.6 0.0 6.5 6 0 0 6 6 6 2 RNA helicase ABC_tran PF00005.27 EMC99014.1 - 1.5e-12 48.2 5.0 0.044 14.3 0.0 7.3 7 0 0 7 7 6 3 ABC transporter RsgA_GTPase PF03193.16 EMC99014.1 - 1.7e-12 47.5 0.3 0.045 13.7 0.0 5.5 5 0 0 5 5 5 2 RsgA GTPase T2SSE PF00437.20 EMC99014.1 - 5.1e-12 45.4 5.8 0.017 14.2 0.0 6.4 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_14 PF13173.6 EMC99014.1 - 6.1e-12 45.7 0.0 0.015 15.3 0.0 7.3 7 0 0 7 7 6 2 AAA domain AAA_19 PF13245.6 EMC99014.1 - 8.9e-12 45.6 1.1 0.51 10.7 0.1 7.4 6 0 0 6 6 6 1 AAA domain Zeta_toxin PF06414.12 EMC99014.1 - 1.2e-11 44.2 5.3 0.025 13.9 0.1 7.0 7 0 0 7 7 6 2 Zeta toxin Mg_chelatase PF01078.21 EMC99014.1 - 3.1e-11 43.1 5.9 0.086 12.2 0.2 8.5 8 1 1 9 9 9 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EMC99014.1 - 1.2e-10 41.6 0.3 0.022 14.7 0.0 4.9 5 0 0 5 5 4 2 Rad17 P-loop domain RuvB_N PF05496.12 EMC99014.1 - 1.2e-09 38.2 4.7 0.36 10.5 0.0 6.5 7 0 0 7 7 5 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EMC99014.1 - 4.1e-09 36.6 17.5 0.24 11.3 0.1 7.1 8 0 0 8 8 6 4 NACHT domain AAA_29 PF13555.6 EMC99014.1 - 1.1e-08 34.7 2.2 1.4 8.7 0.1 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 EMC99014.1 - 1.3e-08 34.7 0.4 0.12 12.1 0.0 5.1 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EMC99014.1 - 5e-08 32.6 1.0 3 7.2 0.0 6.2 7 0 0 7 7 5 0 Bacterial TniB protein SRP54 PF00448.22 EMC99014.1 - 4.1e-07 29.8 10.1 0.17 11.5 0.0 5.3 6 0 0 6 6 5 3 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 EMC99014.1 - 1.5e-06 28.0 0.6 4.8 6.9 0.0 5.8 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_28 PF13521.6 EMC99014.1 - 1.9e-06 28.2 9.7 1.7 8.9 0.0 6.8 6 0 0 6 6 5 2 AAA domain ResIII PF04851.15 EMC99014.1 - 6.5e-06 26.3 0.4 4.2 7.3 0.0 5.0 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit Roc PF08477.13 EMC99014.1 - 7.7e-06 26.1 1.4 4.3 7.6 0.0 5.4 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EMC99014.1 - 2e-05 24.3 11.5 0.12 11.9 0.1 6.6 8 0 0 8 8 5 1 AAA domain TIP49 PF06068.13 EMC99014.1 - 2.6e-05 23.6 2.3 0.77 8.9 0.0 5.7 6 0 0 6 6 6 1 TIP49 P-loop domain AAA_24 PF13479.6 EMC99014.1 - 4.3e-05 23.3 1.0 11 5.7 0.0 5.8 6 0 0 6 6 6 0 AAA domain ATPase_2 PF01637.18 EMC99014.1 - 4.9e-05 23.4 0.0 3.4 7.5 0.0 5.7 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EMC99014.1 - 7.7e-05 23.3 9.3 0.11 13.0 0.0 5.7 6 0 0 6 6 4 1 AAA domain NTPase_1 PF03266.15 EMC99014.1 - 0.00019 21.4 7.9 4.9 7.0 0.0 5.3 5 0 0 5 5 4 0 NTPase DEAD PF00270.29 EMC99014.1 - 0.00024 20.9 0.1 2.3 8.0 0.0 4.9 4 0 0 4 4 4 1 DEAD/DEAH box helicase NB-ARC PF00931.22 EMC99014.1 - 0.00055 19.2 0.2 32 3.6 0.0 5.5 6 0 0 6 6 5 0 NB-ARC domain SRPRB PF09439.10 EMC99014.1 - 0.00056 19.4 2.5 20 4.6 0.0 5.3 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EMC99014.1 - 0.00076 19.5 3.7 48 4.1 0.1 5.9 6 0 0 6 6 5 0 50S ribosome-binding GTPase ATPase PF06745.13 EMC99014.1 - 0.0051 16.2 0.2 11 5.3 0.0 4.6 5 0 0 5 5 4 0 KaiC AAA_8 PF12780.7 EMC99014.1 - 0.01 15.1 2.7 6.3 6.0 0.0 5.2 7 0 0 7 7 6 0 P-loop containing dynein motor region D4 MobB PF03205.14 EMC99014.1 - 0.011 15.6 4.5 0.63 9.9 0.0 4.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 EMC99014.1 - 0.012 15.0 1.4 21 4.3 0.1 4.2 4 0 0 4 4 4 0 FtsK/SpoIIIE family G-alpha PF00503.20 EMC99014.1 - 0.015 14.5 0.1 19 4.2 0.0 3.8 4 0 0 4 4 4 0 G-protein alpha subunit Septin PF00735.18 EMC99014.1 - 0.015 14.6 0.6 11 5.2 0.0 3.8 4 0 0 4 4 4 0 Septin CbiA PF01656.23 EMC99014.1 - 0.018 15.1 4.8 13 5.8 0.0 4.9 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EMC99014.1 - 0.056 12.4 0.8 8.5 5.3 0.0 3.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CPT PF07931.12 EMC99014.1 - 0.057 13.3 1.7 23 4.8 0.0 4.9 4 1 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 EMC99014.1 - 0.13 12.7 7.3 32 5.0 0.0 5.5 6 0 0 6 6 4 0 AAA domain VWA_2 PF13519.6 EMC99014.1 - 0.15 12.7 0.9 1 10.1 0.1 3.0 2 0 0 2 2 1 0 von Willebrand factor type A domain Dynamin_N PF00350.23 EMC99014.1 - 0.17 12.0 0.0 20 5.2 0.0 3.3 3 0 0 3 3 2 0 Dynamin family IPT PF01745.16 EMC99014.1 - 0.26 10.6 2.9 3.9 6.8 0.0 3.7 4 0 0 4 4 3 0 Isopentenyl transferase PhoH PF02562.16 EMC99014.1 - 0.52 9.7 4.6 11 5.4 0.1 4.1 5 0 0 5 5 5 0 PhoH-like protein dNK PF01712.19 EMC99014.1 - 0.79 9.5 8.2 19 5.0 0.0 4.5 5 0 0 5 5 3 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 EMC99014.1 - 1.2 8.9 9.2 10 5.8 0.1 5.2 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein SKI PF01202.22 EMC99014.1 - 8.1 6.5 8.1 6.8 6.8 0.1 4.2 5 0 0 5 5 3 0 Shikimate kinase CTK3 PF12243.8 EMC99015.1 - 1.2e-42 144.8 0.0 1.7e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EMC99015.1 - 2.6e-21 75.5 7.8 2.6e-21 75.5 7.8 1.6 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Voltage_CLC PF00654.20 EMC99016.1 - 6.5e-92 308.5 25.2 1e-91 307.8 25.2 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EMC99016.1 - 1.3e-06 28.8 0.0 0.0036 17.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain WD40 PF00400.32 EMC99017.1 - 6.4e-33 112.3 13.6 4.4e-08 33.7 1.7 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Tmemb_170 PF10190.9 EMC99017.1 - 1e-22 80.5 14.4 1.4e-22 80.0 14.4 1.2 1 0 0 1 1 1 1 Putative transmembrane protein 170 ANAPC4_WD40 PF12894.7 EMC99017.1 - 5.2e-13 49.1 0.7 0.11 12.8 0.0 6.4 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMC99017.1 - 0.0011 19.0 0.0 0.24 11.2 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A SLC35F PF06027.12 EMC99018.1 - 2.8e-90 302.9 21.6 3.5e-90 302.6 21.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EMC99018.1 - 4.8e-11 42.2 6.1 6.5e-11 41.8 6.1 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like HCV_env PF01539.17 EMC99018.1 - 6.3e-05 22.7 1.7 0.00015 21.5 1.7 1.6 1 0 0 1 1 1 1 Hepatitis C virus envelope glycoprotein E1 DUF3659 PF12396.8 EMC99019.1 - 2.3e-18 65.9 1.5 3.8e-18 65.2 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) SMK-1 PF04802.15 EMC99020.1 - 3.6e-75 252.0 4.7 6.2e-75 251.2 4.7 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Mif2_N PF15624.6 EMC99020.1 - 0.26 12.0 8.8 0.81 10.4 8.5 2.0 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal PBP1_TM PF14812.6 EMC99020.1 - 3.2 8.2 6.3 10 6.6 3.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pectate_lyase_3 PF12708.7 EMC99022.1 - 4.8e-96 320.7 23.1 1.5e-83 279.9 7.9 3.1 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EMC99022.1 - 2e-06 27.4 3.0 0.0056 16.3 0.4 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase EBP PF05241.12 EMC99024.1 - 8.4e-70 233.8 9.9 1.1e-69 233.5 9.9 1.1 1 0 0 1 1 1 1 Emopamil binding protein CBFD_NFYB_HMF PF00808.23 EMC99026.1 - 5.2e-11 42.7 0.9 1.6e-10 41.1 0.9 1.8 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMC99026.1 - 2.2 8.6 10.4 0.56 10.6 2.7 2.9 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Aldedh PF00171.22 EMC99027.1 - 8.9e-162 538.8 0.6 1e-161 538.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3102 PF11300.8 EMC99027.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) DUF4604 PF15377.6 EMC99027.1 - 0.16 12.4 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Glycos_transf_2 PF00535.26 EMC99028.1 - 4.7e-23 81.9 0.0 1.5e-22 80.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMC99028.1 - 3.1e-05 24.0 0.0 0.018 15.0 0.0 3.0 3 0 0 3 3 3 2 Glycosyltransferase like family 2 BTB PF00651.31 EMC99029.1 - 4e-08 33.5 0.0 6.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RNase_PH PF01138.21 EMC99031.1 - 2.1e-27 96.2 0.0 3.3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EMC99031.1 - 1.7e-07 31.2 0.1 3.8e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 EMC99032.1 - 3.1e-81 272.7 25.5 3.6e-81 272.6 25.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 EMC99032.1 - 7.3 5.3 11.6 9.1 4.9 11.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SURF2 PF05477.11 EMC99032.1 - 7.9 6.1 16.4 12 5.4 16.2 1.4 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) COesterase PF00135.28 EMC99033.1 - 4.4e-71 240.3 1.4 6.3e-63 213.4 0.5 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC99033.1 - 7.7e-07 29.2 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold adh_short_C2 PF13561.6 EMC99035.1 - 2.9e-55 187.4 0.3 3.5e-55 187.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC99035.1 - 3.9e-47 160.2 1.4 4.7e-47 160.0 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC99035.1 - 7.4e-13 48.8 0.4 1.8e-12 47.6 0.2 1.7 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.10 EMC99035.1 - 0.00028 20.3 0.1 0.00036 20.0 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMC99035.1 - 0.00064 19.3 0.2 0.0011 18.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 EMC99035.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Eno-Rase_NADH_b PF12242.8 EMC99035.1 - 0.23 11.2 1.1 0.45 10.3 0.5 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CDC14 PF08045.11 EMC99036.1 - 6.1e-114 379.9 0.9 6.9e-114 379.8 0.9 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component UNC45-central PF11701.8 EMC99036.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central CMD PF02627.20 EMC99037.1 - 3.2e-10 39.9 0.0 3e-09 36.8 0.0 2.1 1 1 1 2 2 2 1 Carboxymuconolactone decarboxylase family adh_short_C2 PF13561.6 EMC99038.1 - 4.9e-43 147.4 0.0 5.8e-42 143.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC99038.1 - 2.2e-39 134.9 0.1 1.1e-37 129.4 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC99038.1 - 3.8e-09 36.7 0.1 5.6e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 KR domain CDC24_OB3 PF17244.2 EMC99041.1 - 0.0026 17.5 0.0 0.12 12.0 0.0 2.9 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 tRNA_anti-codon PF01336.25 EMC99041.1 - 0.0031 17.5 0.0 0.029 14.3 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RNase_PH PF01138.21 EMC99042.1 - 2.7e-17 63.5 0.0 7.6e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 eIF-5_eIF-2B PF01873.17 EMC99043.1 - 1.4e-40 137.8 0.0 2.6e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EMC99043.1 - 1.2e-19 70.2 0.3 1.2e-19 70.2 0.3 2.8 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Formyl_trans_N PF00551.19 EMC99044.1 - 1e-38 132.9 0.1 1.3e-38 132.5 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EMC99044.1 - 5.9e-08 32.3 0.0 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EMC99044.1 - 3.1e-05 23.9 0.0 9.5e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 ACT domain ZnuA PF01297.17 EMC99044.1 - 0.056 12.8 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF3801 PF12687.7 EMC99044.1 - 0.15 12.1 0.1 1.5 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) GTP_cyclohydro2 PF00925.20 EMC99045.1 - 2e-55 186.9 0.0 4.1e-55 185.8 0.0 1.5 1 1 0 1 1 1 1 GTP cyclohydrolase II Zip PF02535.22 EMC99048.1 - 1.8e-55 188.5 6.4 1.3e-54 185.7 4.5 2.4 2 1 0 2 2 2 1 ZIP Zinc transporter stn_TNFRSF12A PF12191.8 EMC99048.1 - 0.029 14.6 0.2 0.074 13.3 0.1 1.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF445 PF04286.12 EMC99048.1 - 0.27 11.0 0.7 0.5 10.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Methyltransf_25 PF13649.6 EMC99049.1 - 1.1e-06 29.2 0.1 2.1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC99049.1 - 0.00025 20.9 0.0 0.00031 20.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 EMC99050.1 - 1.7e-73 246.1 0.0 3.7e-73 244.9 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EMC99050.1 - 8.5e-25 86.4 0.2 1.4e-24 85.7 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EMC99050.1 - 1.8e-05 25.3 0.0 4.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC99050.1 - 5.5e-05 23.0 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC99050.1 - 0.0015 19.3 0.1 0.008 16.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 EMC99050.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 EMC99050.1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pmp3 PF01679.17 EMC99051.1 - 8e-25 86.8 8.2 8.9e-25 86.6 8.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Phage_holin_Dp1 PF16938.5 EMC99051.1 - 0.12 12.6 3.3 1.7 8.9 3.3 2.0 1 1 0 1 1 1 0 Putative phage holin Dp-1 Iwr1 PF08574.10 EMC99052.1 - 8.5e-16 58.7 10.5 8.5e-16 58.7 10.5 2.3 2 0 0 2 2 2 1 Transcription factor Iwr1 Solute_trans_a PF03619.16 EMC99053.1 - 1.8e-59 201.5 2.4 2.2e-59 201.2 2.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Ribo_biogen_C PF04034.13 EMC99053.1 - 0.082 12.6 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Ribosome biogenesis protein, C-terminal VASt PF16016.5 EMC99054.1 - 7.3e-36 123.9 0.0 1.2e-35 123.2 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EMC99054.1 - 1.3e-24 86.3 0.1 7.5e-24 83.8 0.0 2.1 2 0 0 2 2 2 1 GRAM domain DUF4637 PF15470.6 EMC99054.1 - 1.5 8.6 8.8 5.3 6.8 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4637) Cofilin_ADF PF00241.20 EMC99055.1 - 6.7e-32 109.8 0.0 2.6e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Lactonase PF10282.9 EMC99056.1 - 2.7e-30 105.8 0.0 8.2e-30 104.2 0.0 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EMC99056.1 - 0.024 14.2 0.0 0.14 11.8 0.0 2.2 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EMC99056.1 - 0.083 13.0 0.1 0.28 11.3 0.1 2.0 1 0 0 1 1 1 0 NHL repeat MFS_1 PF07690.16 EMC99057.1 - 6.7e-32 110.8 36.6 6.7e-32 110.8 36.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CAF1 PF04857.20 EMC99058.1 - 6.9e-78 262.0 0.0 8.2e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 EMC99058.1 - 0.00026 20.7 0.0 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 3'-5' exonuclease Pex26 PF07163.12 EMC99059.1 - 0.019 14.3 9.7 0.86 8.9 9.3 3.0 2 1 0 2 2 2 0 Pex26 protein DDHD PF02862.17 EMC99059.1 - 0.084 13.0 2.8 0.16 12.1 2.8 1.6 1 0 0 1 1 1 0 DDHD domain GREB1 PF15782.5 EMC99059.1 - 0.13 9.4 3.4 0.15 9.2 3.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 EMC99059.1 - 0.19 10.5 7.2 0.28 9.9 7.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPAT_C PF15712.5 EMC99059.1 - 0.3 9.7 12.8 0.41 9.2 12.8 1.1 1 0 0 1 1 1 0 NPAT C terminus CPSF100_C PF13299.6 EMC99059.1 - 0.86 9.8 7.5 1.6 8.9 7.5 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EMC99059.1 - 1 7.6 17.1 1.5 7.0 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 EMC99059.1 - 1.6 7.7 13.5 2.7 7.0 13.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF4569 PF15133.6 EMC99059.1 - 1.7 8.3 10.0 2.6 7.7 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) MCM_bind PF09739.9 EMC99059.1 - 1.9 6.8 9.2 2.4 6.5 8.4 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor Merozoite_SPAM PF07133.11 EMC99059.1 - 2.5 8.1 17.7 4.5 7.2 17.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SLC12 PF03522.15 EMC99059.1 - 2.7 6.9 9.3 4 6.4 9.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Ndc1_Nup PF09531.10 EMC99059.1 - 3 6.4 9.2 4.8 5.7 9.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5401 PF17380.2 EMC99059.1 - 3.8 5.5 19.6 5.3 5.0 19.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF5427 PF10310.9 EMC99059.1 - 5.4 5.9 18.8 8 5.3 18.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Borrelia_P83 PF05262.11 EMC99059.1 - 5.7 5.3 13.5 7.9 4.8 13.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein XRN_M PF17846.1 EMC99059.1 - 5.9 5.7 8.4 8.5 5.2 8.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Apt1 PF10351.9 EMC99059.1 - 6.5 5.5 16.1 10 4.8 16.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FUSC PF04632.12 EMC99061.1 - 0.52 8.8 3.3 0.63 8.5 3.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AMPK1_CBM PF16561.5 EMC99062.1 - 8.7e-07 29.1 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase UCH PF00443.29 EMC99064.1 - 8.4e-64 215.5 0.0 1.2e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC99064.1 - 1.3e-10 41.4 0.1 0.00088 19.0 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EMC99064.1 - 2.4e-08 34.5 0.0 6.2e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 DUSP domain ubiquitin PF00240.23 EMC99064.1 - 0.0093 15.7 0.0 0.031 14.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family USP7_C2 PF14533.6 EMC99064.1 - 0.13 11.9 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal Abhydrolase_1 PF00561.20 EMC99065.1 - 2e-43 148.9 0.0 1.1e-42 146.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EMC99065.1 - 0.0007 19.3 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase SH3-RhoG_link PF16609.5 EMC99065.1 - 0.038 13.7 0.1 0.096 12.4 0.0 1.5 1 1 0 1 1 1 0 SH3-RhoGEF linking unstructured region FCH PF00611.23 EMC99067.1 - 7.4e-28 96.6 5.7 2.3e-27 95.1 0.2 3.0 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EMC99067.1 - 4.1e-16 58.6 0.2 7.8e-07 28.9 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EMC99067.1 - 5.7e-14 51.5 0.0 8.1e-07 28.6 0.0 2.6 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 EMC99067.1 - 6e-13 48.5 2.1 9.8e-13 47.8 2.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_10 PF17902.1 EMC99067.1 - 0.00068 19.7 0.0 0.86 9.7 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EMC99067.1 - 0.0014 18.3 0.0 0.16 11.7 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain C1_2 PF03107.16 EMC99067.1 - 0.052 13.9 3.8 0.11 12.8 3.8 1.5 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 EMC99067.1 - 1.1 9.2 6.0 2.3 8.2 6.0 1.5 1 0 0 1 1 1 0 PHD-finger FapA PF03961.13 EMC99067.1 - 1.3 7.6 6.2 2.4 6.7 6.2 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-F_leu_zip PF10473.9 EMC99067.1 - 9.4 6.3 10.8 0.81 9.7 3.6 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DEAD PF00270.29 EMC99068.1 - 5.4e-32 111.0 0.1 1e-31 110.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC99068.1 - 6.6e-26 90.8 0.1 2.4e-25 89.0 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC99068.1 - 0.00013 22.0 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMC99068.1 - 0.0009 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ceramidase PF05875.12 EMC99069.1 - 3e-78 262.9 7.8 3.6e-78 262.6 7.8 1.0 1 0 0 1 1 1 1 Ceramidase DUF998 PF06197.13 EMC99069.1 - 0.017 14.8 0.5 0.017 14.8 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF998) SID-1_RNA_chan PF13965.6 EMC99069.1 - 8.1 4.7 10.7 16 3.8 10.7 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Glyco_hydro_3_C PF01915.22 EMC99070.1 - 1e-45 156.2 0.1 2.2e-45 155.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMC99070.1 - 2.3e-24 86.4 0.0 3.4e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DDR PF08841.10 EMC99070.1 - 0.2 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Isy1 PF06246.12 EMC99071.1 - 1.4e-88 296.8 4.0 1.6e-88 296.5 4.0 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 EMC99071.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 YolD-like protein Methyltransf_31 PF13847.6 EMC99072.1 - 9.9e-26 90.4 0.0 1.2e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC99072.1 - 3.4e-23 82.1 0.0 6.5e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC99072.1 - 1.5e-22 80.1 0.0 2.6e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMC99072.1 - 1.1e-15 57.6 0.0 1.6e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EMC99072.1 - 2.5e-15 57.0 0.0 3.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC99072.1 - 1.1e-10 41.5 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC99072.1 - 2.8e-06 27.0 0.0 4.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 EMC99072.1 - 6.3e-06 26.0 0.0 9.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_4 PF02390.17 EMC99072.1 - 2.5e-05 23.8 0.0 6.4e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 EMC99072.1 - 0.00013 21.8 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EMC99072.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DREV PF05219.12 EMC99072.1 - 0.0025 17.0 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase FtsJ PF01728.19 EMC99072.1 - 0.01 16.0 0.0 0.016 15.3 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EMC99072.1 - 0.049 13.4 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 EMC99072.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 EMC99072.1 - 0.089 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RNA_pol_Rpb1_1 PF04997.12 EMC99073.1 - 1.6e-106 356.1 0.0 3.1e-106 355.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EMC99073.1 - 8.8e-102 340.1 0.0 1.2e-101 339.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EMC99073.1 - 2e-75 252.6 0.0 3.4e-75 251.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EMC99073.1 - 5.1e-57 192.8 0.3 8.9e-57 192.0 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 EMC99073.1 - 6.5e-44 149.2 0.9 1.3e-43 148.2 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 EMC99073.1 - 8e-44 149.3 0.0 1.5e-43 148.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EMC99073.1 - 2.6e-34 117.4 0.1 8.5e-34 115.8 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EMC99073.1 - 8.2e-18 63.7 237.1 0.0079 16.5 10.5 16.0 11 3 9 20 20 20 17 RNA polymerase Rpb1 C-terminal repeat Med27 PF11571.8 EMC99073.1 - 0.056 13.8 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 27 zf-C4pol PF14260.6 EMC99073.1 - 0.22 12.0 0.3 0.54 10.8 0.3 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta WD40 PF00400.32 EMC99074.1 - 5.1e-15 55.6 5.6 0.00074 20.3 0.2 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC99074.1 - 1.2e-10 41.6 0.0 2.6e-07 30.9 0.0 4.4 3 3 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMC99074.1 - 0.00031 20.7 0.1 2.2 8.1 0.0 3.1 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A SesA PF17107.5 EMC99075.1 - 0.048 13.8 1.9 0.068 13.4 0.1 2.1 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TetR_C_13 PF16925.5 EMC99075.1 - 0.081 12.9 0.5 0.15 12.0 0.5 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Apolipoprotein PF01442.18 EMC99075.1 - 1.8 8.4 9.1 10 6.0 9.1 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Senescence PF06911.12 EMC99076.1 - 1.4e-53 181.9 2.4 2e-53 181.4 2.4 1.2 1 0 0 1 1 1 1 Senescence-associated protein TrkH PF02386.16 EMC99077.1 - 4.2e-102 342.2 2.6 5.1e-97 325.4 0.2 2.0 2 0 0 2 2 2 2 Cation transport protein PCI PF01399.27 EMC99078.1 - 5e-05 23.8 0.0 6.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 EMC99078.1 - 0.001 18.9 0.4 0.0026 17.6 0.1 1.7 2 0 0 2 2 2 1 COP9 signalosome complex subunit 7a helix I domain CLZ PF16526.5 EMC99079.1 - 2.8 8.4 8.3 4.9 7.6 0.5 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 EMC99079.1 - 7.6 7.2 6.6 5.5 7.7 0.2 2.6 2 0 0 2 2 2 0 SlyX Ras PF00071.22 EMC99080.1 - 4.6e-52 175.9 0.0 5.7e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMC99080.1 - 2.3e-18 66.5 0.0 3.8e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMC99080.1 - 7.2e-05 22.3 0.0 9.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.16 EMC99081.1 - 1.1e-23 83.8 40.4 4.5e-23 81.7 40.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2107 PF09880.9 EMC99081.1 - 0.26 11.4 6.8 2.8 8.1 0.0 4.2 5 0 0 5 5 5 0 Predicted membrane protein (DUF2107) Pkinase PF00069.25 EMC99082.1 - 2.2e-43 148.5 0.0 1.1e-42 146.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC99082.1 - 8.9e-26 90.7 0.0 1.4e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMC99082.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Aldo_ket_red PF00248.21 EMC99083.1 - 3.5e-42 144.6 0.0 5.4e-41 140.7 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family MBOAT PF03062.19 EMC99086.1 - 2.8e-19 69.7 15.4 4.3e-19 69.1 15.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EMC99086.1 - 5e-05 23.5 1.0 0.0002 21.6 1.0 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PDR_CDR PF06422.12 EMC99086.1 - 0.045 13.7 0.4 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 CDR ABC transporter Kelch_4 PF13418.6 EMC99087.1 - 2e-26 91.7 8.5 1.2e-07 31.6 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EMC99087.1 - 3.7e-25 87.5 3.9 1.1e-07 31.6 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EMC99087.1 - 1e-24 85.9 3.2 7.1e-07 29.3 0.1 5.5 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EMC99087.1 - 3.3e-19 68.2 1.7 1.7e-05 24.3 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 EMC99087.1 - 2.9e-17 62.5 4.1 6.5e-06 26.3 0.0 6.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EMC99087.1 - 4.1e-17 61.4 8.4 8.2e-06 25.6 0.3 5.0 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 EMC99087.1 - 2e-10 40.9 0.0 3.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 EMC99088.1 - 7.1e-18 64.7 6.5 9.7e-07 29.0 0.1 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EMC99088.1 - 1.3e-16 60.7 17.2 0.00051 20.8 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EMC99088.1 - 1.1e-07 31.1 0.1 7.6e-05 21.8 0.0 3.4 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EMC99088.1 - 1.7e-06 28.1 0.4 0.0026 17.6 0.1 2.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 EMC99088.1 - 0.15 10.9 1.9 0.23 10.3 0.5 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain AMP-binding PF00501.28 EMC99089.1 - 4e-76 256.3 0.0 6.9e-76 255.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EMC99089.1 - 2.8e-58 197.1 0.0 9.7e-58 195.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EMC99089.1 - 2e-53 180.8 1.1 5e-53 179.5 1.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99089.1 - 1.2e-39 136.2 1.3 2.6e-39 135.2 1.3 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC99089.1 - 7e-19 68.4 1.1 2.8e-15 56.7 1.0 2.5 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EMC99089.1 - 2.5e-14 53.4 0.1 2.1e-08 33.9 0.0 3.5 3 2 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMC99089.1 - 2.1e-13 50.4 0.0 5.3e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 EMC99089.1 - 3.2e-08 33.0 1.5 0.00012 21.3 0.0 3.5 4 0 0 4 4 4 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 EMC99089.1 - 1.5e-07 30.7 0.0 0.00017 20.7 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EMC99089.1 - 5.8e-07 29.6 3.3 8.7e-05 22.5 0.8 3.7 4 0 0 4 4 4 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EMC99089.1 - 0.00094 18.4 3.4 0.1 11.7 0.1 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMC99089.1 - 0.012 15.0 0.1 4.5 6.6 0.0 2.9 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EMC99089.1 - 0.94 9.0 2.7 23 4.4 1.5 3.2 3 0 0 3 3 3 0 NmrA-like family Glyco_hydr_30_2 PF14587.6 EMC99090.1 - 6.6e-12 45.7 2.2 5.2e-09 36.2 0.0 3.0 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 EMC99090.1 - 5.7e-11 42.2 2.9 1.3e-10 41.0 2.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 EMC99090.1 - 8.5e-10 38.7 2.2 2.9e-09 37.0 2.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EMC99090.1 - 6.1e-07 28.7 0.3 9.3e-07 28.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain BDV_P40 PF06407.11 EMC99090.1 - 0.055 12.6 0.1 0.091 11.9 0.1 1.3 1 0 0 1 1 1 0 Borna disease virus P40 protein Pmp3 PF01679.17 EMC99094.1 - 2.7e-12 46.7 9.9 3.4e-12 46.4 9.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator GFO_IDH_MocA PF01408.22 EMC99095.1 - 1.7e-18 67.6 0.0 2.6e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF3136 PF11334.8 EMC99095.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3136) ADH_N PF08240.12 EMC99096.1 - 1.4e-26 92.5 1.0 3.1e-26 91.4 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC99096.1 - 3.6e-14 52.8 0.0 5.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMC99096.1 - 7.7e-08 32.1 0.8 2e-05 24.2 0.5 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 EMC99096.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF5593 PF18007.1 EMC99097.1 - 0.12 13.0 0.1 2 9.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5593) PTCRA PF15028.6 EMC99097.1 - 0.36 10.5 2.4 2.2 8.0 0.3 2.3 2 0 0 2 2 2 0 Pre-T-cell antigen receptor ubiquitin PF00240.23 EMC99098.1 - 1.9e-16 59.6 0.0 3.2e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EMC99098.1 - 1.5e-07 31.1 0.0 1.5e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 EMC99098.1 - 0.0001 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMC99098.1 - 0.00059 20.4 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EMC99098.1 - 0.00077 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 EMC99098.1 - 0.016 15.1 34.4 0.97 9.4 3.7 3.6 2 1 1 3 3 3 0 STI1 domain HOIP-UBA PF16678.5 EMC99098.1 - 0.026 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair DUF2477 PF10631.9 EMC99098.1 - 0.59 10.8 4.6 8.9 7.0 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2477) ADH_zinc_N PF00107.26 EMC99099.1 - 1.9e-28 99.0 0.0 4.5e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YEATS PF03366.16 EMC99099.1 - 5.8e-11 42.2 0.1 1.3e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 YEATS family ADH_zinc_N_2 PF13602.6 EMC99099.1 - 7.3e-10 40.0 0.0 3.1e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC99099.1 - 9.1e-06 25.5 0.0 2.9e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain zf-C3HC4_4 PF15227.6 EMC99099.1 - 1.3e-05 25.3 2.1 1.3e-05 25.3 2.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EMC99099.1 - 1.6e-05 24.7 1.1 1.6e-05 24.7 1.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC99099.1 - 2.1e-05 24.3 2.0 2.1e-05 24.3 2.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC99099.1 - 7.1e-05 22.8 2.0 7.1e-05 22.8 2.0 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EMC99099.1 - 0.00059 19.6 3.6 0.015 15.1 1.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC99099.1 - 0.00089 19.2 4.1 0.0031 17.5 4.2 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 EMC99099.1 - 0.0013 18.9 3.4 0.0087 16.2 2.2 2.3 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 EMC99099.1 - 0.0043 17.4 9.0 0.022 15.1 9.0 2.1 1 1 0 1 1 1 1 Ring finger domain AlaDh_PNT_C PF01262.21 EMC99099.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Prok-RING_4 PF14447.6 EMC99099.1 - 0.28 11.1 5.1 8.2 6.4 3.4 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 FOXP-CC PF16159.5 EMC99100.1 - 0.19 12.4 0.1 0.4 11.3 0.1 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain Nucleopor_Nup85 PF07575.13 EMC99101.1 - 1.6e-22 79.8 0.3 4.6e-10 38.7 0.0 3.5 3 1 0 3 3 3 3 Nup85 Nucleoporin TPR_4 PF07721.14 EMC99101.1 - 0.68 10.7 3.4 68 4.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMC99101.1 - 1.2 10.2 5.1 5.9 8.0 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.28 EMC99102.1 - 3e-79 266.6 0.0 3.9e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMC99102.1 - 8e-14 52.4 0.0 1.6e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.19 EMC99103.1 - 7.2e-27 94.5 0.4 7.6e-26 91.2 0.4 2.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC99103.1 - 8.3e-05 22.0 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC99103.1 - 0.00032 20.4 0.3 0.044 13.4 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMC99103.1 - 0.00069 18.6 0.1 0.095 11.5 0.1 2.8 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.10 EMC99103.1 - 0.0016 17.5 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.27 EMC99103.1 - 0.0048 17.4 0.0 0.33 11.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMC99103.1 - 0.039 13.0 0.6 3.8 6.5 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMC99103.1 - 0.19 11.7 0.8 1 9.3 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ysc84 PF04366.12 EMC99106.1 - 4.3e-46 155.8 0.0 7.2e-46 155.1 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Involucrin_N PF10583.9 EMC99106.1 - 0.2 12.3 0.6 0.39 11.3 0.1 1.7 2 0 0 2 2 2 0 Involucrin of squamous epithelia N-terminus DUF155 PF02582.14 EMC99107.1 - 9.7e-53 178.9 1.0 1.5e-52 178.2 1.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SH3_9 PF14604.6 EMC99108.1 - 1.1e-14 54.0 1.0 2e-14 53.2 0.3 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EMC99108.1 - 5.9e-14 51.4 0.2 1.5e-13 50.1 0.2 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EMC99108.1 - 2.8e-12 46.1 0.2 5.6e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 EMC99108.1 - 1.7e-11 44.2 4.5 3.9e-11 43.0 4.6 1.5 2 0 0 2 2 2 1 BAR domain Macoilin PF09726.9 EMC99108.1 - 1.7 7.1 10.2 2.6 6.5 10.2 1.2 1 0 0 1 1 1 0 Macoilin family PI3_PI4_kinase PF00454.27 EMC99109.1 - 3.7e-36 125.2 0.0 3.6e-35 122.0 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 EMC99109.1 - 2.2e-16 59.6 0.0 4.6e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Soyouz_module PF14313.6 EMC99109.1 - 0.012 15.4 0.3 0.078 12.8 0.2 2.2 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) DUF4135 PF13575.6 EMC99109.1 - 0.095 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PI3Ka PF00613.20 EMC99109.1 - 0.2 11.0 0.2 0.41 10.0 0.2 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PCI PF01399.27 EMC99110.1 - 0.00028 21.3 0.0 0.00088 19.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_16 PF13432.6 EMC99110.1 - 0.36 11.5 0.2 0.36 11.5 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat BTB PF00651.31 EMC99111.1 - 1.2e-06 28.8 0.0 4.6e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Cu_amine_oxid PF01179.20 EMC99114.1 - 3.9e-118 394.9 1.8 1.5e-117 393.0 3.1 1.3 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EMC99114.1 - 1.1e-19 69.9 0.1 4.1e-19 68.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) CTP_synth_N PF06418.14 EMC99115.1 - 7.1e-117 389.4 0.2 9.2e-117 389.1 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EMC99115.1 - 2e-52 177.7 0.0 3.1e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EMC99115.1 - 1.9e-07 31.0 0.1 8.2e-07 29.0 0.1 2.1 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 EMC99115.1 - 0.047 13.7 0.0 0.094 12.8 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Aldo_ket_red PF00248.21 EMC99116.1 - 1.8e-48 165.3 0.0 2.6e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family FOXO_KIX_bdg PF16675.5 EMC99116.1 - 0.043 14.1 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 Velvet PF11754.8 EMC99118.1 - 1e-50 173.0 0.4 1.2e-32 113.9 0.0 2.0 1 1 1 2 2 2 2 Velvet factor SE PF08491.10 EMC99120.1 - 2.4e-104 348.3 0.0 3e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EMC99120.1 - 4.8e-11 42.5 0.2 1.7e-10 40.7 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC99120.1 - 1.6e-08 34.6 0.9 9.5e-06 25.4 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMC99120.1 - 6.2e-05 22.3 4.0 0.0034 16.5 2.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EMC99120.1 - 0.00046 19.5 0.0 0.004 16.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EMC99120.1 - 0.001 19.2 0.8 0.0024 18.1 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EMC99120.1 - 0.0024 17.3 3.4 0.0052 16.2 3.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EMC99120.1 - 0.0024 17.0 0.8 0.0082 15.3 0.8 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 EMC99120.1 - 0.013 15.1 0.2 0.025 14.2 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EMC99120.1 - 0.014 14.6 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMC99120.1 - 0.015 15.9 0.4 0.037 14.6 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EMC99120.1 - 0.039 14.0 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 EMC99120.1 - 0.04 13.0 0.8 0.089 11.8 0.6 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 EMC99120.1 - 0.077 11.7 0.2 0.12 11.1 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 EMC99120.1 - 0.084 11.7 3.4 0.59 8.9 0.2 2.3 3 0 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.21 EMC99120.1 - 0.19 11.0 0.2 0.37 10.1 0.2 1.4 1 0 0 1 1 1 0 ThiF family zf-C3HC4 PF00097.25 EMC99121.1 - 8.9e-09 35.1 5.3 8.9e-09 35.1 5.3 5.4 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC99121.1 - 5.3e-08 32.8 4.1 5.3e-08 32.8 4.1 4.3 6 0 0 6 6 6 1 RING-type zinc-finger SH3_1 PF00018.28 EMC99121.1 - 1.3e-06 27.9 0.0 2.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain zf-C3HC4_2 PF13923.6 EMC99121.1 - 3.5e-06 26.8 3.6 3.5e-06 26.8 3.6 5.6 5 3 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.6 EMC99121.1 - 5.1e-06 26.2 0.1 5.1e-06 26.2 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_2 PF13639.6 EMC99121.1 - 5.6e-06 26.6 6.1 5.6e-06 26.6 6.1 5.0 4 1 0 4 4 4 1 Ring finger domain zf-RING_6 PF14835.6 EMC99121.1 - 1.9e-05 24.4 0.5 1.9e-05 24.4 0.5 3.2 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EMC99121.1 - 0.00025 20.9 5.7 0.00025 20.9 5.7 5.5 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EMC99121.1 - 0.00056 20.0 5.6 0.00056 20.0 5.6 5.1 4 2 1 5 5 5 1 zinc finger of C3HC4-type, RING PLA2_B PF01735.18 EMC99122.1 - 4e-108 362.0 4.5 5e-108 361.6 4.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain adh_short_C2 PF13561.6 EMC99123.1 - 1.5e-38 132.7 2.8 3.4e-38 131.5 2.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC99123.1 - 1.5e-26 93.0 1.1 2.3e-26 92.5 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC99123.1 - 9.3e-05 22.4 0.5 0.00092 19.2 0.2 2.1 2 0 0 2 2 2 1 KR domain ArfGap PF01412.18 EMC99124.1 - 8.3e-29 100.0 0.1 1.4e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SAP PF02037.27 EMC99125.1 - 0.00064 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 EMC99125.1 - 0.0008 19.6 5.2 0.0008 19.6 5.2 3.0 2 2 1 3 3 3 2 RNSP1-SAP18 binding (RSB) motif Pinin_SDK_memA PF04696.13 EMC99125.1 - 0.33 11.0 0.1 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region MiAMP1 PF09117.10 EMC99126.1 - 0.002 18.3 1.0 0.024 14.9 0.2 2.3 2 0 0 2 2 2 1 MiAMP1 Amidohydro_1 PF01979.20 EMC99128.1 - 3.8e-18 65.9 0.0 1.3e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMC99128.1 - 4.4e-08 33.0 1.3 6e-05 22.7 0.0 2.9 2 1 1 3 3 3 2 Amidohydrolase family Peptidase_M48 PF01435.18 EMC99129.1 - 2.8e-37 128.4 0.1 6.1e-37 127.3 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M48 MYCBPAP PF14646.6 EMC99129.1 - 0.051 12.5 0.5 0.4 9.6 0.1 2.0 2 0 0 2 2 2 0 MYCBP-associated protein family SurA_N_3 PF13624.6 EMC99129.1 - 0.16 11.7 0.4 1.6 8.5 0.0 2.4 3 0 0 3 3 3 0 SurA N-terminal domain zf-RING_2 PF13639.6 EMC99130.1 - 2.1e-10 40.7 7.9 3.4e-10 40.1 7.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EMC99130.1 - 3.5e-08 33.1 9.0 5.5e-08 32.5 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMC99130.1 - 5.7e-08 32.5 6.1 8.4e-08 32.0 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC99130.1 - 4.8e-06 26.4 8.2 7.6e-06 25.7 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC99130.1 - 6.3e-06 26.0 7.5 9.8e-06 25.4 7.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EMC99130.1 - 2.2e-05 24.7 6.4 4.7e-05 23.6 6.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EMC99130.1 - 0.00018 21.3 5.9 0.00033 20.4 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EMC99130.1 - 0.00043 20.3 4.8 0.0009 19.2 4.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EMC99130.1 - 0.0065 16.2 1.0 0.014 15.1 1.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_10 PF16685.5 EMC99130.1 - 0.12 12.6 6.1 0.21 11.8 5.6 1.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EMC99130.1 - 0.29 11.2 4.9 0.63 10.1 4.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EMC99130.1 - 0.81 9.9 8.5 2.1 8.6 8.5 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EMC99130.1 - 2.9 8.1 8.4 19 5.6 8.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain ETF PF01012.21 EMC99131.1 - 4.2e-45 153.9 0.9 5.3e-45 153.5 0.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain RRM_1 PF00076.22 EMC99132.1 - 1.1e-29 102.0 0.0 2.5e-15 56.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMC99132.1 - 0.00016 21.2 0.0 0.077 12.6 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC99132.1 - 0.0063 16.6 0.0 0.58 10.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif PHM7_cyt PF14703.6 EMC99132.1 - 0.0072 16.6 0.0 10 6.3 0.0 3.1 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter DbpA PF03880.15 EMC99132.1 - 0.012 15.6 0.1 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Limkain-b1 PF11608.8 EMC99132.1 - 0.09 12.9 0.0 23 5.2 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 Flavodoxin_1 PF00258.25 EMC99133.1 - 1.3e-28 100.0 0.0 2.3e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EMC99133.1 - 1.3e-23 83.7 0.0 2.3e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EMC99133.1 - 1.9e-13 51.0 0.0 5.6e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EMC99133.1 - 0.022 15.0 0.0 0.39 10.9 0.0 2.4 1 1 1 2 2 2 0 Flavodoxin domain Flavodoxin_3 PF12641.7 EMC99133.1 - 0.025 14.3 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain HET PF06985.11 EMC99134.1 - 1.7e-22 80.3 0.2 2e-22 80.1 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BPA_C PF18040.1 EMC99134.1 - 0.062 13.2 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 beta porphyranase A C-terminal TGBp3 PF02495.17 EMC99134.1 - 0.1 12.3 0.1 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Triple gene block 3 Dynein_light PF01221.18 EMC99135.1 - 6.2e-37 125.8 2.4 6.8e-37 125.7 2.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.22 EMC99136.1 - 2.2e-73 242.0 0.7 4.7e-19 68.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMC99136.1 - 1.3e-07 31.6 0.0 1.3 9.2 0.0 5.2 5 0 0 5 5 5 2 RNA recognition motif Limkain-b1 PF11608.8 EMC99136.1 - 2.4e-07 30.7 1.4 0.59 10.2 0.0 5.6 5 1 0 5 5 5 3 Limkain b1 Nup35_RRM_2 PF14605.6 EMC99136.1 - 2.1e-05 24.4 0.1 7.5 6.6 0.0 4.5 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EMC99136.1 - 3.3e-05 23.5 0.0 3.3 7.3 0.0 4.0 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EMC99136.1 - 4.9e-05 23.1 0.0 0.74 9.7 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EMC99136.1 - 0.0069 16.4 0.3 14 5.8 0.0 4.3 4 0 0 4 4 4 1 RNA binding motif Amidohydro_1 PF01979.20 EMC99137.1 - 3.4e-24 85.8 0.0 1.7e-23 83.5 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMC99137.1 - 9.1e-13 48.5 0.3 2.2e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EMC99138.1 - 7.9e-24 84.6 0.0 8.6e-24 84.5 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF1899 PF08953.11 EMC99139.1 - 1.4e-35 120.9 0.0 2.4e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EMC99139.1 - 2.8e-21 75.1 0.2 5.6e-21 74.2 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EMC99139.1 - 2.2e-16 59.9 11.7 4.7e-05 24.1 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC99139.1 - 5.3e-07 29.9 0.1 0.0055 17.0 0.1 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMC99139.1 - 0.00052 19.1 0.0 0.038 13.0 0.1 2.4 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EMC99139.1 - 0.012 14.3 2.1 1.1 7.8 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 SSFA2_C PF14723.6 EMC99139.1 - 0.014 15.3 0.7 0.014 15.3 0.7 1.6 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus SlyX PF04102.12 EMC99139.1 - 0.71 10.5 2.0 0.91 10.2 0.5 2.0 2 0 0 2 2 2 0 SlyX Rotamase PF00639.21 EMC99141.1 - 4.5e-20 72.4 0.0 7e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EMC99141.1 - 2.6e-13 50.5 0.0 3.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EMC99141.1 - 5.3e-10 39.2 1.7 5.3e-10 39.2 1.7 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EMC99141.1 - 0.0022 18.8 0.0 0.0035 18.2 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 EMC99141.1 - 0.049 13.3 0.8 0.081 12.6 0.8 1.4 1 0 0 1 1 1 0 WW domain TFIIS_C PF01096.18 EMC99142.1 - 1.1e-11 44.3 6.8 1.1e-11 44.3 6.8 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EMC99142.1 - 9e-10 38.3 2.6 9e-10 38.3 2.6 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 EMC99142.1 - 0.31 11.1 13.7 0.23 11.5 1.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-RRN7 PF11781.8 EMC99142.1 - 4.6 7.0 11.8 6 6.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SET PF00856.28 EMC99144.1 - 4.5e-08 33.7 7.2 4.8e-08 33.6 0.2 3.8 3 2 0 3 3 3 1 SET domain Ribosomal_L14 PF00238.19 EMC99145.1 - 2.5e-47 160.0 1.9 2.7e-47 159.8 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e NSP10 PF09401.10 EMC99145.1 - 0.16 12.0 0.1 0.3 11.1 0.1 1.3 1 1 0 1 1 1 0 RNA synthesis protein NSP10 PH PF00169.29 EMC99146.1 - 1.8e-09 38.1 0.0 4.3e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 EMC99146.1 - 7.8e-06 26.4 0.0 1.8e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein anillin PH_9 PF15410.6 EMC99146.1 - 0.078 13.3 0.1 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DEAD PF00270.29 EMC99148.1 - 3.7e-32 111.5 0.1 1.3e-31 109.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC99148.1 - 3.6e-15 56.3 0.7 2.9e-14 53.4 0.4 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC99148.1 - 0.00019 21.5 0.0 0.001 19.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Lig_C PF18330.1 EMC99148.1 - 0.19 11.7 0.8 0.34 10.9 0.1 1.7 2 0 0 2 2 2 0 Ligase Pab1020 C-terminal region adh_short PF00106.25 EMC99149.1 - 2.4e-23 82.6 0.0 3.1e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99149.1 - 2.9e-15 56.5 0.0 3.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC99149.1 - 8.7e-05 22.5 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC99149.1 - 0.00045 19.8 0.0 0.0005 19.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMC99149.1 - 0.057 12.4 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UCH PF00443.29 EMC99150.1 - 5.1e-34 117.9 0.0 1e-33 116.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC99150.1 - 4.8e-09 36.3 0.0 3.2e-05 23.7 0.0 2.6 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.8 EMC99150.1 - 0.00024 20.1 0.0 0.0086 15.0 0.0 3.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3517) AAA_27 PF13514.6 EMC99150.1 - 0.008 15.8 0.1 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Ribosomal_L18A PF01775.17 EMC99152.1 - 4.3e-45 152.7 2.1 5.4e-45 152.4 2.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Methyltransf_16 PF10294.9 EMC99154.1 - 0.0048 16.7 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase adh_short PF00106.25 EMC99155.1 - 2.1e-25 89.4 1.1 3.4e-21 75.6 0.3 2.3 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99155.1 - 5.6e-16 58.8 1.1 8.7e-15 54.9 1.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC99155.1 - 1.1e-06 28.7 0.2 3.1e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 KR domain zf-C2H2_aberr PF17017.5 EMC99158.1 - 0.0003 21.0 5.2 0.028 14.6 0.0 2.7 3 0 0 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 EMC99158.1 - 0.0023 18.3 15.1 0.038 14.5 1.3 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC99158.1 - 0.0056 17.4 14.6 0.027 15.3 0.9 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMC99158.1 - 0.01 16.2 11.7 0.019 15.4 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMC99158.1 - 0.17 12.2 7.2 1.9 8.9 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 EMC99158.1 - 4.1 7.1 6.7 21 4.9 0.1 3.1 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Amidase PF01425.21 EMC99159.1 - 7.2e-78 262.5 0.0 3.3e-77 260.4 0.0 1.8 1 1 0 1 1 1 1 Amidase Merozoite_SPAM PF07133.11 EMC99160.1 - 0.45 10.5 7.6 0.66 9.9 7.6 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) WD40 PF00400.32 EMC99162.1 - 1.7e-09 38.1 0.2 0.048 14.5 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2939 PF11159.8 EMC99162.1 - 0.077 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) UQ_con PF00179.26 EMC99163.1 - 4.3e-46 156.1 0.0 5.4e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EMC99163.1 - 0.002 18.4 0.0 0.0028 17.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EMC99163.1 - 0.0075 16.0 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B SBDS PF01172.18 EMC99165.1 - 2.8e-22 78.6 0.1 3.2e-22 78.4 0.1 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3328 PF11807.8 EMC99166.1 - 5.4e-32 111.4 0.0 7.3e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ca_hom_mod PF14798.6 EMC99166.1 - 0.061 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator PPP4R2 PF09184.11 EMC99167.1 - 1.1e-09 38.3 5.9 9.5e-09 35.2 0.0 2.6 3 1 0 3 3 3 2 PPP4R2 CLTH PF10607.9 EMC99168.1 - 3.2e-29 101.7 0.0 1e-28 100.1 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EMC99168.1 - 1.9e-24 86.1 0.1 3.4e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EMC99168.1 - 1.6e-05 24.7 0.1 4.4e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 LisH INO80_Ies4 PF08193.11 EMC99169.1 - 2.7e-59 201.1 16.8 3.2e-59 200.9 16.8 1.0 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Glyco_hydro_18 PF00704.28 EMC99170.1 - 2e-20 73.8 0.0 6.8e-20 72.0 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 EMC99171.1 - 7.4e-47 160.0 35.8 8.2e-42 143.4 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EMC99171.1 - 3.3e-05 22.4 1.8 0.00077 17.9 0.1 2.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 EMC99171.1 - 0.001 17.7 35.3 0.0011 17.6 10.6 3.0 2 2 1 3 3 3 2 MFS/sugar transport protein RPA43_OB PF17875.1 EMC99172.1 - 1.4e-22 80.6 8.0 2.4e-22 79.9 0.0 3.5 2 2 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EMC99172.1 - 2.2e-07 31.1 0.0 6.5e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GATase PF00117.28 EMC99173.1 - 5.8e-49 166.5 0.0 7.7e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EMC99173.1 - 4.9e-46 155.7 0.0 2.1e-45 153.7 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EMC99173.1 - 1.5e-06 28.2 0.1 0.00014 21.7 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 FGGY_C PF02782.16 EMC99174.1 - 4.3e-72 242.0 0.9 8.7e-72 241.0 0.9 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EMC99174.1 - 1.6e-62 211.3 0.0 2.3e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 EMC99176.1 - 8.1e-40 136.9 3.9 1e-39 136.6 3.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein IFT46_B_C PF12317.8 EMC99177.1 - 1 9.0 4.9 1.6 8.4 0.9 2.5 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal FlaC_arch PF05377.11 EMC99177.1 - 2 8.9 17.1 1.8 9.1 0.4 5.5 6 1 0 6 6 6 0 Flagella accessory protein C (FlaC) CsbD PF05532.12 EMC99178.1 - 6.8e-16 57.9 14.1 3.7e-10 39.6 0.5 3.2 3 0 0 3 3 3 2 CsbD-like Apo-CIII PF05778.12 EMC99178.1 - 0.088 12.5 0.2 3.6 7.3 0.1 2.7 2 1 1 3 3 3 0 Apolipoprotein CIII (Apo-CIII) UPF0444 PF15475.6 EMC99178.1 - 0.2 11.9 0.2 0.2 11.9 0.2 2.3 3 1 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 Fungal_trans PF04082.18 EMC99179.1 - 1.4e-29 103.0 0.0 2.1e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC99179.1 - 3.2e-07 30.4 15.5 5.5e-07 29.6 15.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dcc1 PF09724.9 EMC99179.1 - 0.025 13.9 0.0 0.078 12.3 0.0 1.8 2 0 0 2 2 2 0 Sister chromatid cohesion protein Dcc1 Engrail_1_C_sig PF10525.9 EMC99179.1 - 0.37 10.0 1.4 0.88 8.8 1.4 1.6 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain bZIP_1 PF00170.21 EMC99179.1 - 3.6 7.8 5.9 0.54 10.4 0.4 2.5 3 0 0 3 3 3 0 bZIP transcription factor ArAE_1_C PF11728.8 EMC99180.1 - 0.011 15.8 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain SET PF00856.28 EMC99180.1 - 0.023 15.1 0.0 0.044 14.2 0.0 1.7 1 1 0 1 1 1 0 SET domain ThrE PF06738.12 EMC99182.1 - 1.3e-70 237.5 16.9 1.4e-69 234.2 1.0 3.0 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EMC99182.1 - 1.6e-05 25.1 2.8 1.6e-05 25.1 2.8 4.3 4 1 0 4 4 4 2 Threonine/Serine exporter, ThrE NAD_kinase PF01513.21 EMC99183.1 - 7.2e-78 261.7 0.0 9.6e-78 261.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DSPn PF14671.6 EMC99184.1 - 5e-40 137.2 0.0 1.3e-37 129.4 0.0 2.6 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EMC99184.1 - 1e-15 57.8 0.0 2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMC99184.1 - 2.3e-05 24.1 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3439 PF11921.8 EMC99184.1 - 0.21 11.6 2.4 0.5 10.3 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PTPA PF03095.15 EMC99185.1 - 2.8e-109 365.2 0.0 3.2e-109 365.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MFS_1 PF07690.16 EMC99186.1 - 8.6e-46 156.5 28.0 8.6e-46 156.5 28.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC99186.1 - 6e-08 31.6 2.3 9.1e-08 31.0 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMC99186.1 - 4.9e-06 25.7 24.9 2.3e-05 23.5 24.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.9 EMC99186.1 - 6.6 7.0 14.0 4.7 7.4 1.7 3.9 3 1 0 3 3 3 0 Predicted membrane protein (DUF2178) Nup188_C PF18378.1 EMC99187.1 - 3.3e-88 296.0 0.0 9.7e-88 294.5 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EMC99187.1 - 6.7e-42 143.5 0.0 2.4e-32 111.9 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 CLTH PF10607.9 EMC99190.1 - 2.9e-27 95.4 0.0 8.6e-27 93.8 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EMC99190.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 LisH GIT_CC PF16559.5 EMC99190.1 - 0.067 13.1 1.5 1.5 8.8 0.2 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF484 PF04340.12 EMC99190.1 - 0.2 11.3 7.0 0.063 13.0 4.1 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF484 TPR_4 PF07721.14 EMC99190.1 - 1.4 9.8 5.1 28 5.7 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L22e PF01776.17 EMC99191.1 - 1.1e-43 148.0 0.1 1.3e-43 147.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1160 PF06648.11 EMC99191.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) NmrA PF05368.13 EMC99192.1 - 2.9e-14 53.2 0.0 4.1e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC99192.1 - 1.2e-13 51.3 0.1 2.2e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC99192.1 - 9.9e-06 25.2 0.2 1.4e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EMC99192.1 - 0.0074 16.4 0.2 0.015 15.4 0.2 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 EMC99192.1 - 0.015 15.4 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 EMC99192.1 - 0.017 14.1 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.16 EMC99192.1 - 0.019 14.6 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Semialdhyde_dh PF01118.24 EMC99192.1 - 0.065 13.7 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 EMC99192.1 - 0.079 13.6 0.0 4.7 8.0 0.0 3.2 4 0 0 4 4 4 0 CoA binding domain RmlD_sub_bind PF04321.17 EMC99192.1 - 0.11 11.6 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 EMC99192.1 - 0.14 12.8 0.2 0.41 11.3 0.2 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 EMC99192.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Ldh_1_N PF00056.23 EMC99192.1 - 0.16 12.1 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 EMC99193.1 - 6.3e-55 186.7 49.9 7.9e-55 186.4 49.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC99193.1 - 8.3e-20 70.8 38.4 1.2e-19 70.3 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF5592 PF17332.2 EMC99193.1 - 0.69 10.5 5.9 0.2 12.3 2.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5592) zf-C2H2 PF00096.26 EMC99194.1 - 0.011 16.1 4.0 0.51 10.9 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type TBX PF12598.8 EMC99194.1 - 0.045 14.5 0.6 0.23 12.3 0.6 2.4 1 0 0 1 1 1 0 T-box transcription factor GSHPx PF00255.19 EMC99197.1 - 2.4e-39 133.2 0.1 3.1e-39 132.9 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EMC99197.1 - 8.6e-05 22.5 0.0 0.00053 19.9 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EMC99197.1 - 0.012 15.3 0.2 0.021 14.5 0.2 1.5 1 1 0 1 1 1 0 Redoxin FAD_binding_3 PF01494.19 EMC99198.1 - 4.5e-17 62.3 0.1 7.5e-16 58.3 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC99198.1 - 0.00087 19.0 0.0 0.3 10.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 EMC99198.1 - 0.0011 18.0 0.0 0.0027 16.8 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 EMC99198.1 - 0.0019 17.3 0.0 0.063 12.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EMC99198.1 - 0.0024 17.9 0.2 0.015 15.3 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EMC99198.1 - 0.031 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMC99198.1 - 0.058 12.1 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 EMC99198.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ILVD_EDD PF00920.21 EMC99199.1 - 2.5e-211 702.8 0.1 2.9e-211 702.6 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family F-box PF00646.33 EMC99200.1 - 0.00012 21.8 0.3 0.00031 20.5 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EMC99200.1 - 0.0026 17.6 0.3 0.0026 17.6 0.3 2.1 3 0 0 3 3 3 1 F-box-like GDPD PF03009.17 EMC99201.1 - 9.9e-37 127.1 0.0 1.2e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF1400 PF07176.11 EMC99201.1 - 0.015 15.6 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) GDPD_2 PF13653.6 EMC99201.1 - 0.046 14.2 1.4 0.17 12.4 1.4 2.1 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Tubulin PF00091.25 EMC99202.1 - 9.4e-66 221.8 0.0 2.1e-65 220.6 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMC99202.1 - 3e-42 143.8 0.2 8.5e-42 142.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EMC99202.1 - 1.3e-05 25.5 0.0 5e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EMC99202.1 - 0.035 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Nop16 PF09420.10 EMC99203.1 - 1.9e-58 198.0 11.0 2.1e-58 197.8 11.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF5024 PF16427.5 EMC99203.1 - 0.059 13.7 0.3 0.39 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5024) DUF1547 PF07577.11 EMC99203.1 - 0.11 12.8 0.1 0.58 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Oxidored_FMN PF00724.20 EMC99204.1 - 6.9e-42 143.9 0.0 9.4e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1772 PF08592.11 EMC99205.1 - 2.7e-19 69.9 6.3 3.3e-19 69.6 6.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2040 PF09745.9 EMC99207.1 - 2e-37 128.0 22.8 2e-37 128.0 22.8 2.9 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF1117 PF06547.12 EMC99207.1 - 9.8 6.8 9.2 0.91 10.1 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) Patatin PF01734.22 EMC99209.1 - 6.9e-21 75.4 0.0 1.7e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.27 EMC99209.1 - 0.0001 22.9 0.0 0.00032 21.2 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMC99209.1 - 0.0054 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EMC99209.1 - 0.0075 16.3 0.0 0.023 14.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EMC99209.1 - 0.015 15.6 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-RING_UBOX PF13445.6 EMC99209.1 - 0.055 13.5 10.9 0.19 11.8 10.9 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Zeta_toxin PF06414.12 EMC99209.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin UIM PF02809.20 EMC99209.1 - 0.12 12.4 0.3 0.41 10.7 0.3 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif TsaE PF02367.17 EMC99209.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-B_box PF00643.24 EMC99209.1 - 2.6 8.3 14.6 0.068 13.3 3.4 2.9 2 0 0 2 2 2 0 B-box zinc finger zf-C3HC4 PF00097.25 EMC99209.1 - 8.3 6.4 10.1 29 4.6 10.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Hexapep PF00132.24 EMC99210.1 - 5.8e-16 57.5 7.1 2.2e-09 36.7 2.8 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMC99210.1 - 9e-14 50.9 5.3 3.6e-09 36.2 1.6 3.3 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Ferrochelatase PF00762.19 EMC99211.1 - 4.5e-96 321.7 0.0 5.3e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.16 EMC99212.1 - 1.9e-44 151.8 0.0 3.4e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EMC99212.1 - 2.3e-31 109.3 0.0 3.1e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EMC99212.1 - 5e-25 88.0 0.0 1.3e-24 86.7 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.6 EMC99212.1 - 0.12 13.0 0.0 0.89 10.2 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain YL1 PF05764.13 EMC99213.1 - 3.8e-37 128.7 35.9 3.8e-37 128.7 35.9 1.8 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 EMC99213.1 - 1.4e-07 31.1 0.1 2.8e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Acetate_kinase PF00871.17 EMC99214.1 - 1.8e-99 333.1 0.0 2.1e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family SNARE PF05739.19 EMC99215.1 - 6.4e-16 58.1 0.3 1.8e-15 56.7 0.3 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EMC99215.1 - 1.2e-06 28.3 9.3 1.2e-06 28.3 9.3 2.1 2 1 0 2 2 2 1 Syntaxin DNA_repr_REX1B PF14966.6 EMC99215.1 - 0.0019 18.8 0.2 0.0064 17.1 0.2 1.9 1 0 0 1 1 1 1 DNA repair REX1-B DASH_Dad4 PF08650.10 EMC99215.1 - 0.16 12.0 0.5 0.62 10.1 0.0 2.2 2 1 0 2 2 2 0 DASH complex subunit Dad4 SlyX PF04102.12 EMC99215.1 - 0.16 12.6 8.3 0.31 11.7 0.2 3.0 2 1 0 2 2 2 0 SlyX Syntaxin_2 PF14523.6 EMC99215.1 - 0.25 11.8 9.4 0.9 9.9 3.7 3.0 2 1 1 3 3 3 0 Syntaxin-like protein ATP_Ca_trans_C PF12424.8 EMC99215.1 - 0.67 10.5 2.9 0.6 10.6 0.3 2.2 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal Sec2p PF06428.11 EMC99215.1 - 9.8 6.2 9.1 0.44 10.6 1.0 2.6 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p EF-hand_1 PF00036.32 EMC99216.1 - 1.4e-41 137.0 12.9 8.3e-10 37.5 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EMC99216.1 - 4.1e-36 123.3 5.8 4.3e-19 68.7 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EMC99216.1 - 8.5e-35 118.4 11.8 2.6e-15 56.0 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EMC99216.1 - 8.7e-31 103.2 8.1 2e-09 36.6 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EMC99216.1 - 7.8e-26 88.4 10.6 2.8e-06 26.6 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EMC99216.1 - 1.7e-16 60.3 0.4 2.5e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EMC99216.1 - 3.7e-09 36.5 3.7 0.00079 19.3 0.2 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EMC99216.1 - 4.7e-09 36.6 0.3 0.0018 18.6 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EMC99216.1 - 1.2e-06 28.5 0.4 0.0086 16.1 0.0 3.2 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EMC99216.1 - 7.5e-06 26.0 1.6 2.5e-05 24.2 0.2 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EMC99216.1 - 9.6e-05 23.2 0.2 0.0024 18.7 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EMC99216.1 - 0.00014 21.9 0.6 0.4 10.6 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EMC99216.1 - 0.00053 20.0 1.7 0.47 10.4 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EMC99216.1 - 0.00064 20.0 0.8 0.59 10.5 0.2 2.7 2 1 0 2 2 2 2 RNA polymerase Rpb4 DUF3349 PF11829.8 EMC99216.1 - 0.0007 20.3 0.4 1.8 9.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 EMC99216.1 - 0.0023 18.1 6.1 0.41 10.9 0.8 3.2 1 1 3 4 4 4 2 Dockerin type I domain DUF5580 PF17743.1 EMC99216.1 - 0.0065 15.1 0.0 0.0067 15.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 EMC99216.1 - 0.011 15.7 1.0 0.35 10.7 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 EMC99216.1 - 0.013 15.8 0.5 6.9 7.1 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 EMC99216.1 - 0.022 15.0 0.0 0.16 12.2 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 EMC99216.1 - 0.023 15.2 0.0 9.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 EMC99216.1 - 0.062 13.8 0.1 9.1 6.8 0.0 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 EMC99216.1 - 0.064 12.4 0.2 1.1 8.3 0.1 2.2 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 EMC99216.1 - 0.064 13.4 0.3 0.97 9.6 0.0 2.4 1 1 0 2 2 2 0 Transcription factor MotA, activation domain RloB PF13707.6 EMC99216.1 - 0.13 12.4 1.1 0.84 9.8 1.1 2.0 1 1 0 1 1 1 0 RloB-like protein DUF5132 PF17195.4 EMC99216.1 - 0.15 12.2 0.5 22 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Abhydrolase_1 PF00561.20 EMC99218.1 - 2e-48 165.3 0.0 2.9e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMC99218.1 - 0.00038 21.1 1.3 0.00074 20.2 1.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EMC99218.1 - 0.00051 19.0 0.0 0.00071 18.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EMC99218.1 - 0.008 15.5 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_M14 PF00246.24 EMC99219.1 - 2.3e-73 247.5 0.0 2.9e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Ribosomal_L7Ae PF01248.26 EMC99220.1 - 1.2e-19 69.8 0.4 6.8e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family polyprenyl_synt PF00348.17 EMC99221.1 - 8.2e-65 218.4 0.0 9.7e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Cortexin PF11057.8 EMC99221.1 - 0.11 12.4 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Cortexin of kidney Helo_like_N PF17111.5 EMC99223.1 - 0.00083 18.8 0.0 0.00093 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 EMC99226.1 - 1.2e-19 70.7 3.3 0.074 13.6 0.6 11.0 6 4 3 11 11 11 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EMC99226.1 - 9.7e-17 61.1 8.6 0.28 11.8 0.0 12.1 13 2 2 15 15 15 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC99226.1 - 2.8e-10 39.5 8.1 5.3 7.9 0.0 13.8 16 0 0 16 16 16 1 Ankyrin repeat Ank PF00023.30 EMC99226.1 - 8.9e-07 29.1 6.2 25 5.5 0.0 9.9 10 0 0 10 10 10 1 Ankyrin repeat Ank_5 PF13857.6 EMC99226.1 - 1.4e-05 25.3 5.9 15 6.1 0.0 8.0 8 1 0 8 8 8 1 Ankyrin repeats (many copies) W2 PF02020.18 EMC99226.1 - 0.042 14.0 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Alpha_kinase PF02816.18 EMC99227.1 - 9.7e-51 172.5 0.0 1.8e-50 171.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 EMC99227.1 - 6.4e-11 42.8 0.0 1.7e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EMC99227.1 - 0.00038 20.8 0.0 0.00077 19.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Amidohydro_2 PF04909.14 EMC99228.1 - 2.1e-24 86.8 0.2 2.5e-24 86.6 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Complex1_LYR PF05347.15 EMC99230.1 - 3.1e-16 59.1 0.2 3.6e-16 58.9 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EMC99230.1 - 3.8e-05 24.4 0.0 4.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EMC99230.1 - 0.041 14.5 0.8 0.1 13.2 0.1 1.7 1 1 1 2 2 2 0 Complex1_LYR-like BRCT PF00533.26 EMC99231.1 - 0.027 14.8 0.0 0.61 10.5 0.0 2.8 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EMC99231.1 - 0.04 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain STE2 PF02116.15 EMC99232.1 - 6.3e-62 209.4 17.4 7.5e-62 209.2 17.4 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF1754 PF08555.10 EMC99233.1 - 4.2e-15 56.3 13.9 6.8e-15 55.7 13.9 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 EMC99233.1 - 0.0052 16.2 8.4 0.0057 16.1 8.4 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 EccE PF11203.8 EMC99233.1 - 0.089 13.1 0.4 0.14 12.5 0.1 1.5 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE G-gamma PF00631.22 EMC99233.1 - 0.73 9.9 3.0 0.48 10.5 0.6 1.9 2 0 0 2 2 2 0 GGL domain Asp-B-Hydro_N PF05279.11 EMC99233.1 - 2.1 8.3 11.3 2.6 8.0 11.3 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1682 PF07946.14 EMC99233.1 - 8.6 5.5 12.4 11 5.2 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CDC45 PF02724.14 EMC99233.1 - 8.7 4.5 12.2 10 4.3 12.2 1.0 1 0 0 1 1 1 0 CDC45-like protein HhH-GPD PF00730.25 EMC99234.1 - 3.6e-20 72.4 0.0 7.7e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EMC99234.1 - 7.5e-09 35.0 0.1 2.2e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif CPSF73-100_C PF11718.8 EMC99234.1 - 0.056 13.0 0.6 0.084 12.4 0.0 1.6 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term UEV PF05743.13 EMC99236.1 - 2.9e-34 117.5 0.0 4.9e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EMC99236.1 - 5.8e-17 61.4 0.1 5.8e-17 61.4 0.1 1.8 2 0 0 2 2 2 1 Vps23 core domain APG17 PF04108.12 EMC99236.1 - 0.19 10.8 3.1 0.3 10.1 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 ATG16 PF08614.11 EMC99236.1 - 2.1 8.5 8.7 0.51 10.5 1.4 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FliD_N PF02465.18 EMC99236.1 - 6.4 7.5 6.6 1.5 9.5 1.3 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3450 PF11932.8 EMC99236.1 - 7.8 5.7 10.1 4.9 6.4 6.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) G-alpha PF00503.20 EMC99237.1 - 5.2e-123 410.7 1.4 6e-123 410.5 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EMC99237.1 - 2.6e-15 56.3 1.7 1.2e-10 41.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EMC99237.1 - 0.00016 21.4 0.0 0.00069 19.4 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EMC99237.1 - 0.0017 17.8 3.6 0.079 12.3 0.1 2.8 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EMC99237.1 - 0.013 15.3 0.1 0.042 13.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 EMC99237.1 - 0.014 14.5 0.1 0.033 13.3 0.0 1.4 1 1 0 1 1 1 0 MCM P-loop domain Roc PF08477.13 EMC99237.1 - 0.015 15.5 0.6 2.5 8.3 0.0 2.8 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EMC99237.1 - 0.098 12.8 0.0 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EMC99237.1 - 0.11 12.0 0.1 1.8 8.1 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 EMC99237.1 - 0.14 11.5 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family IPU_b_solenoid PF18783.1 EMC99240.1 - 0.061 13.4 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Isopullulanase beta-solenoid repeat LIM PF00412.22 EMC99241.1 - 4.5e-21 74.8 22.5 3.2e-12 46.5 3.9 2.8 3 0 0 3 3 3 2 LIM domain WRC PF08879.10 EMC99241.1 - 0.0015 18.2 0.1 0.59 9.9 0.1 2.5 2 0 0 2 2 2 2 WRC Ribosomal_L5e PF17144.4 EMC99242.1 - 9.3e-81 269.6 0.3 9.3e-81 269.6 0.3 1.8 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EMC99242.1 - 3e-34 117.8 11.8 3e-34 117.8 11.8 2.3 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 EMC99242.1 - 0.031 14.5 1.7 0.41 10.9 0.0 3.1 4 0 0 4 4 4 0 Threonine synthase N terminus BORCS6 PF10157.9 EMC99243.1 - 0.0046 17.2 0.8 0.024 14.9 0.1 2.3 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 6 MFS_1 PF07690.16 EMC99244.1 - 1.8e-31 109.4 30.8 1.8e-31 109.4 30.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DBD_Tnp_Mut PF03108.15 EMC99244.1 - 0.19 11.7 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase TauD PF02668.16 EMC99245.1 - 3.4e-51 174.6 0.1 4e-51 174.4 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_3 PF07859.13 EMC99246.1 - 1.1e-28 100.6 0.2 1.6e-28 100.1 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EMC99246.1 - 2.9e-22 79.1 0.0 3.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EMC99246.1 - 0.0041 16.6 0.2 0.057 12.9 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Lipase PF00151.19 EMC99246.1 - 0.14 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Lipase F-box-like PF12937.7 EMC99247.1 - 4.3e-07 29.7 1.8 2.5e-06 27.3 1.8 2.5 1 1 0 1 1 1 1 F-box-like NIF PF03031.18 EMC99249.1 - 1.3e-55 187.5 0.0 1.5e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CAP_N PF01213.19 EMC99249.1 - 0.96 8.9 3.1 1.3 8.4 3.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAD_binding_2 PF00890.24 EMC99250.1 - 1.6e-45 156.0 0.5 2.7e-44 151.9 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMC99250.1 - 2.3e-07 30.8 0.9 2.3e-07 30.8 0.9 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EMC99250.1 - 8.2e-05 21.5 0.3 0.07 11.8 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 EMC99250.1 - 0.00013 21.4 0.0 0.017 14.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMC99250.1 - 0.00023 20.6 0.3 0.0021 17.5 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EMC99250.1 - 0.0082 16.7 0.3 1.2 9.7 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EMC99250.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase Lycopene_cycl PF05834.12 EMC99250.1 - 0.015 14.4 0.1 0.025 13.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMC99250.1 - 0.049 13.9 0.1 0.19 12.0 0.1 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CBM_21 PF03370.13 EMC99251.1 - 2.4e-34 117.9 0.2 3.7e-34 117.3 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EMC99251.1 - 4.3e-08 33.6 1.9 8.4e-08 32.7 1.9 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) BolA PF01722.18 EMC99253.1 - 1.1e-13 51.3 0.0 4.4e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 BolA-like protein Metallophos PF00149.28 EMC99254.1 - 1.9e-10 41.6 0.0 3.4e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PI3Ka PF00613.20 EMC99255.1 - 4.9e-55 185.8 0.3 7.3e-55 185.2 0.3 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EMC99255.1 - 1.3e-43 149.6 0.0 1.7e-29 103.4 0.0 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EMC99255.1 - 1.4e-30 106.1 0.0 2.6e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 EMC99256.1 - 1.3e-34 118.3 0.0 3.5e-34 116.9 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EMC99256.1 - 5.8e-16 58.3 2.9 6.8e-16 58.1 0.0 2.5 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE AAA_11 PF13086.6 EMC99256.1 - 0.057 13.2 4.2 0.41 10.4 0.9 2.4 2 0 0 2 2 2 0 AAA domain adh_short_C2 PF13561.6 EMC99257.1 - 2.7e-60 203.9 0.7 3.4e-60 203.5 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC99257.1 - 7.6e-47 159.3 1.9 9.4e-47 159.0 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EMC99257.1 - 0.00074 19.1 0.3 0.0064 16.0 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC99257.1 - 0.00091 19.2 0.1 0.0012 18.8 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Spond_N PF06468.13 EMC99257.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Spondin_N DLH PF01738.18 EMC99258.1 - 1.3e-20 73.9 0.1 1.5e-20 73.7 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EMC99258.1 - 0.098 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.16 EMC99259.1 - 1.1e-29 103.5 31.0 1.5e-29 103.0 31.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMC99259.1 - 0.0035 16.3 15.9 0.014 14.3 15.8 2.0 1 1 0 1 1 1 1 MFS_1 like family Fungal_trans PF04082.18 EMC99260.1 - 6.7e-11 41.7 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC99260.1 - 6.5e-07 29.4 9.8 1.3e-06 28.4 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Longin PF13774.6 EMC99260.1 - 0.051 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain TFIIE_alpha PF02002.17 EMC99261.1 - 2e-15 56.5 0.9 3.3e-14 52.6 0.1 2.8 2 1 0 2 2 2 1 TFIIE alpha subunit zf-FPG_IleRS PF06827.14 EMC99261.1 - 0.014 15.2 2.2 0.054 13.4 0.2 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-TFIIB PF13453.6 EMC99261.1 - 0.03 13.7 3.0 0.95 8.8 0.2 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger DZR PF12773.7 EMC99261.1 - 0.032 14.2 0.3 0.072 13.1 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-IS66 PF13005.7 EMC99261.1 - 0.037 14.4 1.8 0.84 10.1 0.2 2.9 3 0 0 3 3 2 0 zinc-finger binding domain of transposase IS66 zf_Rg PF17915.1 EMC99261.1 - 0.074 12.5 0.3 0.16 11.4 0.3 1.5 1 0 0 1 1 1 0 Reverse gyrase zinc finger zf-ribbon_3 PF13248.6 EMC99261.1 - 0.086 12.3 3.5 0.52 9.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EMC99261.1 - 0.095 12.8 1.3 16 5.7 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Rrf2 PF02082.20 EMC99261.1 - 0.14 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator zf_C2H2_10 PF18414.1 EMC99261.1 - 0.18 11.4 5.8 1 9.0 0.1 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger TF_Zn_Ribbon PF08271.12 EMC99261.1 - 0.27 10.8 3.0 1.4 8.5 0.4 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding zf_UBZ PF18439.1 EMC99261.1 - 0.28 10.8 2.6 0.84 9.3 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 EMC99261.1 - 0.32 10.8 2.7 1.3 8.8 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 EMC99261.1 - 0.37 10.5 0.1 0.37 10.5 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 EMC99261.1 - 4.7 7.3 5.3 8.3 6.5 1.0 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon PseudoU_synth_1 PF01416.20 EMC99262.1 - 1.1e-07 32.3 0.0 4.7e-06 27.0 0.0 2.8 3 0 0 3 3 3 1 tRNA pseudouridine synthase MgtE_N PF03448.17 EMC99262.1 - 0.024 15.2 0.1 0.069 13.8 0.1 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain DUF2344 PF10105.9 EMC99262.1 - 0.13 12.1 0.0 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Glyco_transf_90 PF05686.12 EMC99263.1 - 3.4e-27 95.4 0.0 4.3e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 adh_short PF00106.25 EMC99264.1 - 9e-15 54.6 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99264.1 - 2.6e-10 40.3 0.0 3.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EMC99264.1 - 1.1e-06 28.6 0.2 1.8e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMC99264.1 - 2.2e-06 27.7 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EMC99264.1 - 2.5e-05 24.0 2.8 4.3e-05 23.2 2.8 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EMC99264.1 - 0.0014 18.1 0.1 0.0027 17.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC99264.1 - 0.0026 17.2 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EMC99264.1 - 0.0086 16.6 0.2 0.015 15.9 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OGFr_N PF04664.13 EMC99265.1 - 3.6e-15 56.0 0.0 5.2e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region CFEM PF05730.11 EMC99266.1 - 4.7e-06 26.6 6.1 9.3e-06 25.7 6.1 1.4 1 0 0 1 1 1 1 CFEM domain DUF3431 PF11913.8 EMC99267.1 - 1.7e-13 50.9 0.0 3e-13 50.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Sugar_tr PF00083.24 EMC99269.1 - 8.5e-41 140.3 19.3 1.6e-40 139.4 19.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC99269.1 - 1.4e-13 50.5 29.3 2.3e-13 49.8 29.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1993 PF09351.10 EMC99270.1 - 1.7e-47 161.5 0.0 2e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Sugar_tr PF00083.24 EMC99271.1 - 2.6e-97 326.5 30.3 3.1e-97 326.3 30.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC99271.1 - 1.9e-20 73.1 44.6 2.5e-19 69.4 44.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.22 EMC99272.1 - 4.5e-39 133.9 0.0 5.9e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 EMC99273.1 - 1.6e-17 63.4 0.0 2.1e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MIS13 PF08202.11 EMC99274.1 - 2e-43 148.8 0.0 3.3e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family HalX PF08663.10 EMC99274.1 - 0.3 11.4 4.5 1.1 9.6 0.4 3.2 3 1 0 3 3 3 0 HalX domain AMP-binding PF00501.28 EMC99275.1 - 4.3e-43 147.5 0.0 5.9e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Urb2 PF10441.9 EMC99276.1 - 2e-46 158.5 0.9 8.1e-46 156.5 0.9 2.2 1 0 0 1 1 1 1 Urb2/Npa2 family DUF543 PF04418.12 EMC99277.1 - 1.1e-29 102.2 0.0 1.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Glyco_hydro_67M PF07488.12 EMC99278.1 - 3.7e-142 473.2 0.2 5e-142 472.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 EMC99278.1 - 7.6e-83 277.4 0.8 1.2e-82 276.8 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 EMC99278.1 - 5e-27 94.6 0.0 9.3e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus BetaGal_dom4_5 PF13364.6 EMC99278.1 - 0.021 15.4 2.7 0.046 14.3 0.6 2.5 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain DUF5638 PF18688.1 EMC99278.1 - 0.48 10.7 1.2 0.65 10.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5638) HK PF02110.15 EMC99279.1 - 2.8e-76 256.1 0.7 4.5e-76 255.5 0.7 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EMC99279.1 - 4.3e-58 195.6 7.1 1.3e-57 194.0 5.4 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 EMC99279.1 - 0.00017 21.0 0.0 0.0005 19.5 0.0 1.7 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 EMC99279.1 - 0.0019 17.8 0.2 0.0042 16.6 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate kinase Pinin_SDK_memA PF04696.13 EMC99280.1 - 2.3e-24 85.9 13.5 2.3e-24 85.9 13.5 1.4 1 1 1 2 2 2 2 pinin/SDK/memA/ protein conserved region TrwC PF08751.11 EMC99280.1 - 0.047 13.2 5.9 0.044 13.3 5.0 1.4 2 0 0 2 2 2 0 TrwC relaxase DNA_pol_B_thumb PF14791.6 EMC99281.1 - 4.2e-20 71.7 0.1 9.8e-20 70.5 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EMC99281.1 - 8.4e-20 70.4 0.9 2.6e-19 68.8 0.5 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 EMC99281.1 - 1.4e-17 64.0 0.1 5.8e-17 62.0 0.1 2.0 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 EMC99281.1 - 1.1e-08 35.3 0.0 3e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain MMR_HSR1 PF01926.23 EMC99282.1 - 1.5e-12 47.6 0.0 2.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMC99282.1 - 1.7e-05 24.8 0.2 4e-05 23.6 0.2 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EMC99282.1 - 0.00055 20.4 0.0 0.0011 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EMC99282.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.13 EMC99282.1 - 0.0057 15.8 0.1 0.0094 15.0 0.1 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 EMC99282.1 - 0.081 13.0 0.4 0.79 9.8 0.1 2.3 1 1 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 EMC99282.1 - 0.1 11.9 0.1 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 EMC99282.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Septin Zn_clus PF00172.18 EMC99283.1 - 4.6e-07 29.8 11.8 9.8e-07 28.8 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.8 EMC99284.1 - 5e-24 85.3 0.1 5.3e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GrpB PF04229.14 EMC99286.1 - 2.2e-47 161.2 0.0 2.6e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 GrpB protein Zn_clus PF00172.18 EMC99287.1 - 1.6e-08 34.5 8.8 2.9e-08 33.7 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMC99287.1 - 0.0094 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EMC99288.1 - 2.5e-25 89.1 0.0 1.5e-24 86.6 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99288.1 - 8.9e-15 54.9 0.0 1.8e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC99288.1 - 1.1e-06 28.7 0.1 2.7e-06 27.4 0.0 1.7 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 EMC99288.1 - 2.7e-05 23.8 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMC99288.1 - 0.004 16.6 0.0 0.68 9.3 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EMC99288.1 - 0.2 10.8 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Acetyltransf_10 PF13673.7 EMC99289.1 - 5.6e-08 32.8 0.1 1.2e-07 31.7 0.2 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMC99289.1 - 2.4e-06 27.9 0.5 3.9e-06 27.2 0.5 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC99289.1 - 2.7e-05 24.4 0.1 4.3e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Copper-fist PF00649.18 EMC99290.1 - 3.5e-08 32.8 7.0 3.5e-08 32.8 7.0 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain Methyltransf_16 PF10294.9 EMC99291.1 - 1.7e-16 60.4 0.0 2.2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EMC99291.1 - 0.0018 18.2 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EMC99291.1 - 0.0019 17.7 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EMC99291.1 - 0.016 15.9 0.0 0.03 15.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EMC99291.1 - 0.026 13.7 0.0 0.088 12.0 0.0 1.7 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family GidB PF02527.15 EMC99291.1 - 0.041 13.2 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PCMT PF01135.19 EMC99291.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) KTI12 PF08433.10 EMC99292.1 - 2.6e-81 273.1 0.0 2.9e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EMC99292.1 - 0.081 13.1 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Med13_C PF06333.12 EMC99293.1 - 0.31 10.2 5.9 0.35 10.1 5.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SNF2_N PF00176.23 EMC99296.1 - 5e-63 212.9 0.5 8.1e-63 212.2 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC99296.1 - 8.4e-16 58.3 0.0 2.3e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC99296.1 - 3.5e-10 40.2 3.0 6.8e-10 39.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 EMC99296.1 - 3.4e-09 36.4 2.0 7.8e-09 35.3 2.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EMC99296.1 - 1.6e-05 24.7 0.1 8.8e-05 22.3 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 EMC99296.1 - 3.6e-05 23.6 3.0 8.7e-05 22.4 3.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMC99296.1 - 0.00053 19.8 2.0 0.00053 19.8 2.0 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC99296.1 - 0.0017 18.6 4.0 0.0046 17.3 2.4 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EMC99296.1 - 0.0026 17.6 5.2 0.016 15.0 5.6 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EMC99296.1 - 0.0089 16.0 3.7 0.011 15.7 1.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger ERCC3_RAD25_C PF16203.5 EMC99296.1 - 0.023 13.9 0.0 0.054 12.7 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Nop14 PF04147.12 EMC99296.1 - 0.13 10.4 14.7 0.2 9.8 14.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EMC99296.1 - 0.15 10.3 14.8 0.24 9.7 14.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Prok-RING_4 PF14447.6 EMC99296.1 - 0.26 11.2 5.1 2 8.3 5.1 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 BTV_NS2 PF04514.12 EMC99296.1 - 0.26 10.1 6.6 0.42 9.4 6.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sigma70_ner PF04546.13 EMC99296.1 - 1.1 9.1 12.6 3 7.7 12.6 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.13 EMC99296.1 - 2.3 8.2 21.0 5.1 7.1 21.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein zf-C3HC4_4 PF15227.6 EMC99296.1 - 2.4 8.4 7.6 0.83 9.9 2.5 2.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING CN_hydrolase PF00795.22 EMC99298.1 - 1.3e-58 198.4 0.0 1.5e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Rotavirus_VP3 PF06929.11 EMC99298.1 - 0.072 11.3 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein adh_short PF00106.25 EMC99299.1 - 2.8e-32 111.7 0.0 3.5e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99299.1 - 4.1e-23 82.2 0.0 4.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thg1C PF14413.6 EMC99302.1 - 4.4e-50 168.9 0.0 6.1e-50 168.5 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 EMC99302.1 - 8.2e-50 168.0 0.0 1.3e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Pro-kuma_activ PF09286.11 EMC99303.1 - 5.6e-49 166.1 0.1 2.8e-48 163.8 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain UDPGP PF01704.18 EMC99304.1 - 1.2e-52 179.0 0.0 1.6e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EMC99304.1 - 0.053 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF4188 PF13826.6 EMC99306.1 - 1.1e-23 83.8 0.4 1.6e-23 83.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) RRP7 PF12923.7 EMC99307.1 - 5.3e-30 104.0 6.9 8.1e-30 103.4 6.9 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EMC99307.1 - 4.9e-21 75.2 0.0 1.9e-20 73.3 0.0 1.9 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 EMC99307.1 - 0.0015 18.3 0.0 0.091 12.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KAR9 PF08580.10 EMC99308.1 - 4.4 5.7 9.0 5.7 5.4 9.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SNF2_N PF00176.23 EMC99309.1 - 2.4e-61 207.4 0.4 3.8e-61 206.8 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMC99309.1 - 2.5e-15 56.8 0.0 6.9e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC99309.1 - 1.6e-08 34.7 0.2 5.8e-07 29.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PIEZO PF15917.5 EMC99309.1 - 2.7 7.4 6.9 15 4.9 6.9 2.4 1 0 0 1 1 1 0 Piezo NDUF_B8 PF05821.11 EMC99310.1 - 8.1e-10 38.8 0.3 1e-09 38.5 0.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DYW_deaminase PF14432.6 EMC99312.1 - 0.0097 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases Clr2_transil PF16761.5 EMC99314.1 - 8.9e-17 61.7 0.9 1.8e-16 60.7 0.9 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EMC99314.1 - 1.5e-11 45.3 0.0 7.7e-11 43.0 0.0 2.2 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 Response_reg PF00072.24 EMC99316.1 - 1.6e-25 89.5 0.0 2.7e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EMC99316.1 - 2.8e-25 89.0 0.0 1.4e-24 86.7 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EMC99316.1 - 1.4e-14 53.8 0.0 3.8e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 EMC99316.1 - 0.029 14.2 4.7 0.12 12.1 4.7 2.0 1 1 0 1 1 1 0 Cache domain HAMP PF00672.25 EMC99316.1 - 0.79 10.2 7.7 0.76 10.2 0.1 3.4 3 0 0 3 3 3 0 HAMP domain BBE PF08031.12 EMC99317.1 - 2.7e-07 30.6 0.8 5e-07 29.7 0.8 1.4 1 0 0 1 1 1 1 Berberine and berberine like Aminotran_5 PF00266.19 EMC99319.1 - 2.4e-60 204.5 0.0 3e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMC99319.1 - 0.00065 18.3 0.0 0.0013 17.3 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme ATX_III PF08098.11 EMC99319.1 - 0.088 12.9 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Anemonia sulcata toxin III family Hydrolase_6 PF13344.6 EMC99320.1 - 1e-23 83.4 0.0 1.8e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMC99320.1 - 1.1e-13 51.0 0.0 7.4e-13 48.4 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EMC99320.1 - 0.018 15.3 0.0 12 6.1 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Chorion_S16 PF05836.12 EMC99321.1 - 0.07 13.4 0.2 0.34 11.2 0.0 2.1 3 0 0 3 3 3 0 Chorion protein S16 Pkinase PF00069.25 EMC99322.1 - 2.1e-48 165.0 0.0 2.8e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC99322.1 - 1.2e-18 67.4 0.0 4.6e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EMC99322.1 - 4.2e-05 23.6 0.1 0.0001 22.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EMC99322.1 - 0.24 11.0 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MMR_HSR1_C PF08438.10 EMC99324.1 - 2.9e-35 121.2 0.0 6.5e-35 120.1 0.0 1.6 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EMC99324.1 - 9.4e-21 74.0 0.0 3.4e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMC99324.1 - 2.6e-10 40.1 0.4 8.6e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EMC99324.1 - 0.0045 16.9 0.1 0.73 9.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EMC99324.1 - 0.0073 15.9 0.0 0.82 9.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 EMC99324.1 - 0.0079 16.1 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 EMC99324.1 - 0.011 15.8 0.3 0.056 13.5 0.1 2.2 3 0 0 3 3 3 0 Dynamin family AAA_28 PF13521.6 EMC99324.1 - 0.044 14.0 0.2 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EMC99324.1 - 0.052 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 EMC99324.1 - 0.067 13.0 0.2 12 5.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 EMC99324.1 - 0.15 11.3 0.1 0.32 10.3 0.1 1.5 1 0 0 1 1 1 0 AIG1 family UPF1_Zn_bind PF09416.10 EMC99325.1 - 1.9e-72 242.2 1.1 1.9e-72 242.2 1.1 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EMC99325.1 - 9.4e-56 188.6 0.0 1.6e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMC99325.1 - 8.8e-54 183.0 3.4 1.3e-30 107.1 0.3 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EMC99325.1 - 8.3e-32 109.3 0.0 1.6e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EMC99325.1 - 1.8e-13 50.7 0.5 3.7e-12 46.4 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EMC99325.1 - 9.4e-11 42.2 0.0 7.8e-10 39.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EMC99325.1 - 7.6e-06 26.0 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EMC99325.1 - 0.00074 18.9 0.2 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EMC99325.1 - 0.00077 19.3 0.8 1.5 8.5 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EMC99325.1 - 0.0017 18.2 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 EMC99325.1 - 0.0022 17.6 0.1 0.032 13.8 0.0 2.5 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 EMC99325.1 - 0.0065 16.3 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.7 EMC99325.1 - 0.019 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 EMC99325.1 - 0.048 13.0 0.0 0.73 9.1 0.0 2.3 2 0 0 2 2 2 0 KaiC PIF1 PF05970.14 EMC99325.1 - 0.055 12.6 0.1 4.4 6.4 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 EMC99325.1 - 0.094 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EMC99325.1 - 0.19 12.1 0.0 0.48 10.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-UBP PF02148.19 EMC99325.1 - 1.2 9.5 6.4 3.2 8.2 6.4 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Brix PF04427.18 EMC99326.1 - 8.2e-32 110.9 0.0 1e-31 110.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF1771 PF08590.10 EMC99329.1 - 4.5e-17 62.2 12.0 4.5e-17 62.2 12.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EMC99329.1 - 1e-10 41.8 0.3 2.5e-10 40.6 0.3 1.7 1 0 0 1 1 1 1 Smr domain SUN PF03856.13 EMC99330.1 - 8.4e-88 294.0 21.2 1.2e-87 293.5 21.2 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) AF-4 PF05110.13 EMC99330.1 - 1.1 7.2 15.2 1.4 6.9 15.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 EMC99330.1 - 1.9 6.9 3.0 2.1 6.8 3.0 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 EMC99330.1 - 3.4 6.8 10.7 4.8 6.3 10.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Actin PF00022.19 EMC99332.1 - 7e-112 374.0 0.0 4.6e-111 371.3 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EMC99332.1 - 0.042 12.7 0.0 0.22 10.3 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Band_7 PF01145.25 EMC99333.1 - 5.8e-24 85.1 6.1 7.1e-24 84.8 5.6 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EMC99333.1 - 6.3e-06 25.5 0.9 8.5e-06 25.1 0.9 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial GatB_Yqey PF02637.18 EMC99333.1 - 0.025 14.4 0.5 0.042 13.7 0.5 1.3 1 0 0 1 1 1 0 GatB domain CactinC_cactus PF09732.9 EMC99333.1 - 0.2 11.6 0.1 0.34 10.9 0.1 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein AAA_lid_4 PF17864.1 EMC99333.1 - 0.48 10.2 4.5 0.34 10.7 0.1 2.6 2 1 1 3 3 3 0 RuvB AAA lid domain Maf1 PF09174.10 EMC99335.1 - 9.3e-59 198.5 0.0 1.2e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Type_III_YscX PF09474.10 EMC99335.1 - 0.016 15.5 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Clat_adaptor_s PF01217.20 EMC99337.1 - 7e-52 175.1 1.1 8.4e-52 174.9 1.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EMC99337.1 - 0.028 15.2 0.0 0.052 14.3 0.0 1.4 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Aldo_ket_red PF00248.21 EMC99338.1 - 1.9e-10 40.5 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Pcc1 PF09341.10 EMC99340.1 - 1.6e-31 108.2 0.3 2.2e-31 107.8 0.3 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 Asp PF00026.23 EMC99342.1 - 4.3e-58 197.2 2.2 5.9e-58 196.8 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EMC99342.1 - 1.1e-09 38.8 0.8 5.9e-05 23.4 0.0 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EMC99342.1 - 2.6e-05 24.8 0.1 0.46 11.2 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease IDO PF01231.18 EMC99343.1 - 2.7e-164 547.1 0.0 3.1e-164 546.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 EMC99343.1 - 0.092 11.5 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) DSBA PF01323.20 EMC99345.1 - 8.3e-11 42.0 0.0 8.7e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain SPOB_a PF14689.6 EMC99345.1 - 0.14 11.9 0.6 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Aminotran_5 PF00266.19 EMC99347.1 - 1.8e-93 313.5 0.0 2.3e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMC99347.1 - 1.6e-05 24.4 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMC99347.1 - 0.0019 17.5 0.1 0.0076 15.6 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C4 PF00105.18 EMC99347.1 - 0.014 15.9 0.8 0.049 14.1 0.8 1.9 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Use1 PF09753.9 EMC99349.1 - 1.3e-06 28.3 18.6 3.4e-06 27.0 18.5 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 eIF3_subunit PF08597.10 EMC99349.1 - 0.03 14.3 18.0 0.019 14.9 12.3 2.1 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit ODR4-like PF14778.6 EMC99349.1 - 0.064 12.2 2.9 0.048 12.6 0.6 1.8 2 0 0 2 2 2 0 Olfactory receptor 4-like CDC45 PF02724.14 EMC99349.1 - 0.12 10.7 11.8 0.14 10.5 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EMC99349.1 - 0.22 9.5 3.9 0.28 9.2 3.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 EMC99349.1 - 0.26 10.5 6.2 0.39 10.0 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.11 EMC99349.1 - 1.4 8.5 9.6 2 8.0 9.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF641 PF04859.12 EMC99349.1 - 5.7 7.3 12.3 0.057 13.7 1.9 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DivIC PF04977.15 EMC99349.1 - 7.1 6.5 12.2 0.72 9.7 5.8 2.4 2 0 0 2 2 2 0 Septum formation initiator Coatomer_E PF04733.14 EMC99350.1 - 3.2e-46 158.1 0.7 3.6e-46 157.9 0.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EMC99350.1 - 0.0011 19.4 9.5 0.063 13.8 1.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EMC99350.1 - 0.074 13.3 0.2 2.4 8.4 0.0 3.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Gsf2 PF11055.8 EMC99350.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 RNase_H PF00075.24 EMC99351.1 - 7.3e-19 68.4 0.0 1.4e-18 67.5 0.0 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EMC99351.1 - 4e-06 26.7 0.3 0.073 12.9 0.1 2.9 2 1 0 2 2 2 2 Reverse transcriptase-like Methyltransf_34 PF11312.8 EMC99352.1 - 1e-102 343.6 0.0 1.3e-102 343.2 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase FAD_binding_3 PF01494.19 EMC99353.1 - 7.5e-16 58.3 2.6 6.6e-10 38.8 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EMC99353.1 - 6.1e-10 38.8 0.1 0.00091 18.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC99353.1 - 2e-08 33.8 0.3 4.7e-08 32.5 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EMC99353.1 - 2.5e-08 33.1 0.3 0.0002 20.2 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EMC99353.1 - 9.8e-08 32.0 0.7 0.0047 16.5 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 EMC99353.1 - 1.5e-05 24.3 0.3 0.00044 19.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EMC99353.1 - 1.6e-05 24.5 0.3 3.2e-05 23.5 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMC99353.1 - 2.8e-05 23.5 0.0 0.003 16.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EMC99353.1 - 0.0001 21.5 0.5 0.16 11.0 0.2 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 EMC99353.1 - 0.00011 22.3 0.1 0.00026 21.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMC99353.1 - 0.0021 17.3 0.1 0.0038 16.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EMC99353.1 - 0.0035 17.9 0.2 0.17 12.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EMC99353.1 - 0.0066 15.8 0.1 0.017 14.5 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 EMC99353.1 - 0.015 14.6 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 EMC99353.1 - 0.2 11.6 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 EMC99354.1 - 1e-55 189.4 0.0 1.5e-55 188.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 EMC99356.1 - 8.1e-36 123.7 0.0 1.1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC99356.1 - 1.4e-15 57.7 0.0 1.8e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EMC99356.1 - 0.00046 20.1 0.2 0.00072 19.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC99356.1 - 0.00098 18.6 0.0 0.0017 17.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMC99356.1 - 0.0014 17.7 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EMC99356.1 - 0.0042 17.2 0.1 0.0092 16.1 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 EMC99356.1 - 0.0059 16.1 0.6 0.016 14.6 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EMC99356.1 - 0.063 12.4 0.0 2.3 7.3 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.24 EMC99356.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 EMC99357.1 - 9.3e-13 47.7 1.7 1.9e-12 46.7 1.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC99357.1 - 1.1e-07 31.9 7.3 1.8e-07 31.2 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI-PLC-X PF00388.19 EMC99359.1 - 3.9e-63 211.4 0.0 1e-62 210.0 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EMC99359.1 - 4.1e-37 127.0 0.0 9.4e-37 125.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain p25-alpha PF05517.12 EMC99359.1 - 0.12 12.6 0.3 0.3 11.2 0.3 1.7 1 0 0 1 1 1 0 p25-alpha Apidaecin PF00807.17 EMC99360.1 - 0.43 10.7 2.8 0.73 10.0 2.8 1.3 1 0 0 1 1 1 0 Apidaecin Amidase PF01425.21 EMC99362.1 - 2.7e-32 112.3 6.1 1.1e-31 110.3 6.1 1.7 1 1 0 1 1 1 1 Amidase adh_short PF00106.25 EMC99363.1 - 3.7e-30 104.9 0.0 4.6e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99363.1 - 7.9e-24 84.5 0.0 9.5e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMC99363.1 - 9.3e-05 22.0 0.1 0.00017 21.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FtsJ PF01728.19 EMC99363.1 - 0.02 15.0 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase KR PF08659.10 EMC99363.1 - 0.031 14.2 0.5 0.55 10.1 0.5 2.3 1 1 1 2 2 2 0 KR domain RmlD_sub_bind PF04321.17 EMC99363.1 - 0.037 13.1 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 EMC99363.1 - 0.11 12.7 0.0 5.5 7.1 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.18 EMC99364.1 - 2.7e-07 30.6 7.9 4.5e-07 29.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IcmF_C PF06744.12 EMC99365.1 - 0.034 13.8 0.4 0.058 13.0 0.4 1.4 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal Pkinase PF00069.25 EMC99366.1 - 1.5e-60 204.8 0.0 2.5e-59 200.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC99366.1 - 8e-27 94.1 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EMC99366.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 EMC99367.1 - 3.9e-96 322.7 12.4 1.6e-50 172.3 1.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMC99367.1 - 5.3e-27 94.7 46.7 2.8e-19 69.3 22.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMC99367.1 - 4.5e-05 22.2 35.9 0.012 14.2 5.1 4.0 3 1 1 4 4 4 3 MFS/sugar transport protein TRI12 PF06609.13 EMC99367.1 - 7.6e-05 21.3 3.4 7.6e-05 21.3 3.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EMC99367.1 - 0.71 8.1 4.6 1.4 7.1 1.6 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Paramyxo_ncap PF00973.19 EMC99368.1 - 0.078 11.9 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Glyco_hydro_72 PF03198.14 EMC99372.1 - 2.6e-130 434.3 5.0 3.4e-130 433.9 5.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase LRR_4 PF12799.7 EMC99373.1 - 0.0034 17.8 0.3 6.6 7.3 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMC99373.1 - 0.091 12.9 10.3 15 6.0 0.3 5.9 6 0 0 6 6 6 0 Leucine Rich repeat UBM PF14377.6 EMC99374.1 - 0.013 14.9 0.1 0.72 9.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin binding region Transketolase_N PF00456.21 EMC99375.1 - 1.2e-152 507.7 0.1 1.6e-152 507.3 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EMC99375.1 - 3.3e-45 153.9 0.1 5.6e-45 153.2 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMC99375.1 - 5.5e-12 45.6 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EMC99375.1 - 0.00017 20.9 0.0 0.00029 20.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EMC99375.1 - 0.025 13.5 0.1 0.042 12.8 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component GtrA PF04138.14 EMC99375.1 - 0.04 14.1 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 GtrA-like protein Beta_elim_lyase PF01212.21 EMC99375.1 - 0.079 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase COesterase PF00135.28 EMC99376.1 - 3.4e-45 154.9 0.0 6e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMC99376.1 - 0.0073 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC99377.1 - 7.4e-13 48.2 0.1 1.2e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Caleosin PF05042.13 EMC99378.1 - 3.3e-73 245.2 0.1 4e-73 244.9 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.32 EMC99378.1 - 0.00022 20.5 1.4 0.029 13.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EMC99378.1 - 0.00038 20.2 3.7 0.01 15.7 1.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EMC99378.1 - 0.0049 17.3 1.0 0.3 11.6 0.5 2.7 2 1 0 2 2 2 1 EF-hand domain pair Abhydrolase_3 PF07859.13 EMC99379.1 - 1e-38 133.4 0.0 1.3e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC99379.1 - 1.4e-06 27.5 0.1 5.8e-06 25.4 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family GTP_EFTU PF00009.27 EMC99380.1 - 5.2e-41 140.3 0.0 8e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EMC99380.1 - 2.5e-24 85.2 0.0 5.9e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EMC99380.1 - 1.3e-15 57.2 0.0 5.5e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_IV PF03764.18 EMC99380.1 - 2.4e-07 30.5 0.1 0.00064 19.5 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 EMC99380.1 - 3.8e-07 30.4 0.0 8.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EMC99380.1 - 0.00073 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Vps5 PF09325.10 EMC99381.1 - 7.3e-12 45.3 4.9 1.8e-11 44.1 4.9 1.6 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EMC99381.1 - 5.1e-09 36.1 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 PX domain SprA-related PF12118.8 EMC99381.1 - 0.0035 16.5 5.2 0.0035 16.5 5.2 2.1 2 0 0 2 2 2 1 SprA-related family TFIIA PF03153.13 EMC99381.1 - 0.1 12.6 17.9 0.032 14.2 13.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ADH_N PF08240.12 EMC99382.1 - 2.7e-09 36.9 0.4 7e-08 32.3 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC99382.1 - 1e-06 28.8 1.1 1.4e-06 28.3 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Zip PF02535.22 EMC99383.1 - 5.9e-42 144.1 7.9 6e-41 140.8 7.9 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Hat1_N PF10394.9 EMC99384.1 - 1.5e-35 122.8 0.0 2.4e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus E1_dh PF00676.20 EMC99387.1 - 4.9e-115 383.6 0.2 6.3e-115 383.2 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EMC99387.1 - 0.00062 19.1 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase BMC PF00936.19 EMC99387.1 - 0.085 12.9 0.8 0.38 10.8 0.0 2.4 3 0 0 3 3 3 0 BMC domain WD40 PF00400.32 EMC99388.1 - 5.6e-37 125.1 24.2 6.1e-07 30.0 0.1 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EMC99388.1 - 1.5e-10 40.8 0.7 2.7e-10 40.0 0.7 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EMC99388.1 - 2.4e-08 34.2 0.4 0.63 10.4 0.0 5.9 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMC99388.1 - 2.6e-06 26.4 6.3 0.43 9.2 0.0 5.5 2 1 5 7 7 7 4 Nucleoporin Nup120/160 F-box PF00646.33 EMC99388.1 - 5.6e-05 22.9 0.8 0.0001 22.1 0.8 1.5 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 EMC99388.1 - 0.0029 17.0 0.0 0.18 11.1 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 EMC99388.1 - 0.12 12.9 6.6 12 6.6 0.2 4.9 3 2 2 5 5 5 0 PQQ-like domain DUF2835 PF11197.8 EMC99388.1 - 0.16 11.8 0.0 2.6 7.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2835) Mito_carr PF00153.27 EMC99389.1 - 1e-46 156.8 6.0 9.9e-17 60.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2428 PF10350.9 EMC99390.1 - 2.5e-54 184.4 1.5 2.5e-54 184.4 1.5 1.9 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EMC99390.1 - 3.1e-05 23.9 20.3 0.015 15.5 0.1 8.5 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 EMC99390.1 - 0.00035 20.9 8.6 20 5.7 0.2 5.8 5 0 0 5 5 5 3 HEAT repeats Tim17 PF02466.19 EMC99391.1 - 5.2e-26 91.2 5.5 7.2e-26 90.7 5.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PX PF00787.24 EMC99393.1 - 8.3e-17 61.2 0.0 1.9e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EMC99393.1 - 1.7e-06 27.8 8.0 0.0035 16.9 1.6 2.2 2 0 0 2 2 2 2 Vps5 C terminal like HET PF06985.11 EMC99394.1 - 0.013 15.8 0.7 0.16 12.3 0.1 2.3 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Serpin PF00079.20 EMC99395.1 - 0.063 12.6 0.1 0.085 12.2 0.1 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) Keratin_2_head PF16208.5 EMC99395.1 - 0.18 11.9 14.9 0.31 11.1 14.9 1.4 1 0 0 1 1 1 0 Keratin type II head Piwi PF02171.17 EMC99396.1 - 6.8e-59 199.6 0.0 8.2e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Piwi domain DUF4535 PF15054.6 EMC99396.1 - 0.0041 16.8 0.2 0.0078 15.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) RhoGEF67_u2 PF16614.5 EMC99396.1 - 0.088 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 ArgoN PF16486.5 EMC99397.1 - 0.081 13.5 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of argonaute FXMRP1_C_core PF12235.8 EMC99397.1 - 1.3 9.7 7.6 2.2 8.9 7.6 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal IFT57 PF10498.9 EMC99399.1 - 0.012 14.6 2.6 0.016 14.2 2.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Peptidase_M9 PF01752.17 EMC99399.1 - 0.051 12.8 0.3 0.058 12.6 0.3 1.1 1 0 0 1 1 1 0 Collagenase Mis12 PF05859.12 EMC99399.1 - 0.14 12.2 2.3 0.2 11.7 2.3 1.3 1 0 0 1 1 1 0 Mis12 protein FUSC PF04632.12 EMC99399.1 - 6.6 5.1 9.2 7.4 5.0 9.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1325 PF07039.11 EMC99402.1 - 8.9e-28 97.0 0.0 1.6e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain PMI_typeI PF01238.21 EMC99403.1 - 6.7e-144 479.7 0.1 7.9e-144 479.4 0.1 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I tRNA_bind_2 PF13725.6 EMC99403.1 - 0.64 9.7 5.1 0.99 9.1 2.2 2.0 2 0 0 2 2 2 0 Possible tRNA binding domain Glyco_hydro_39 PF01229.17 EMC99404.1 - 0.13 10.8 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 MFS_1 PF07690.16 EMC99405.1 - 4.1e-15 55.6 27.6 9.6e-12 44.5 20.0 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Gly-zipper_YMGG PF13441.6 EMC99405.1 - 0.012 15.3 0.0 0.048 13.4 0.0 2.1 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EMC99405.1 - 7 6.7 13.4 0.083 12.9 2.1 3.1 2 1 0 2 2 2 0 Glycine zipper Arf PF00025.21 EMC99407.1 - 5e-73 244.3 0.2 5.7e-73 244.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMC99407.1 - 2.4e-14 53.6 0.1 3.3e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EMC99407.1 - 5.1e-13 48.9 2.6 3.3e-09 36.4 0.8 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EMC99407.1 - 9.5e-13 48.0 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EMC99407.1 - 1.2e-12 47.7 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EMC99407.1 - 7.4e-11 41.8 0.0 8.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMC99407.1 - 0.00012 22.1 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EMC99407.1 - 0.019 14.3 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 EMC99407.1 - 0.094 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 MobB PF03205.14 EMC99407.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Glyco_transf_8 PF01501.20 EMC99408.1 - 3.2e-07 30.2 0.0 0.0093 15.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 DUF2315 PF10231.9 EMC99408.1 - 0.12 12.4 2.0 0.21 11.7 2.0 1.3 1 0 0 1 1 1 0 Apoptogenic protein 1 Mito_carr PF00153.27 EMC99409.1 - 1.5e-55 185.1 0.3 2.5e-17 62.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_35 PF01301.19 EMC99411.1 - 2.2e-53 182.0 0.1 3.1e-53 181.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EMC99411.1 - 8.2e-09 36.0 0.0 2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Cellulase PF00150.18 EMC99411.1 - 0.003 17.0 0.0 0.0064 16.0 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Mqo PF06039.15 EMC99411.1 - 0.16 10.4 0.1 0.27 9.8 0.1 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) P5CR_dimer PF14748.6 EMC99412.1 - 1e-32 112.4 2.3 2.3e-32 111.3 2.3 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EMC99412.1 - 5.2e-11 43.0 5.7 3.1e-09 37.3 0.0 3.9 3 1 1 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent Methyltransf_25 PF13649.6 EMC99413.1 - 3.8e-07 30.7 0.0 9.4e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC99413.1 - 7.7e-07 29.1 0.0 1.3e-05 25.1 0.0 2.0 1 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 EMC99413.1 - 2.6e-06 27.7 0.0 3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EMC99413.1 - 3.2e-05 23.8 0.1 0.00024 20.9 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC99413.1 - 0.00012 22.6 0.0 0.0002 21.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMC99413.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EMC99413.1 - 0.00023 20.5 0.0 0.00072 18.9 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EMC99413.1 - 0.0011 19.6 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EMC99413.1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_17 PF12692.7 EMC99413.1 - 0.046 13.7 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase CMAS PF02353.20 EMC99413.1 - 0.19 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.16 EMC99414.1 - 3.6e-36 124.8 32.4 3.6e-36 124.8 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC99414.1 - 1.4e-11 43.9 6.9 1.4e-11 43.9 6.9 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3197 PF11432.8 EMC99414.1 - 0.14 12.1 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) MIP PF00230.20 EMC99415.1 - 5.7e-50 170.1 13.4 6.9e-50 169.9 13.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Inhibitor_Mig-6 PF11555.8 EMC99416.1 - 0.0095 16.0 0.2 0.017 15.2 0.2 1.4 1 0 0 1 1 1 1 EGFR receptor inhibitor Mig-6 DUF374 PF04028.13 EMC99416.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF374) MFS_1 PF07690.16 EMC99417.1 - 3.2e-09 36.2 12.3 3.6e-09 36.0 12.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC99417.1 - 9.4e-07 28.0 6.5 1.1e-06 27.9 6.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Lig_chan PF00060.26 EMC99417.1 - 0.11 12.3 0.2 0.14 12.0 0.2 1.1 1 0 0 1 1 1 0 Ligand-gated ion channel Bacteriocin_IIc PF10439.9 EMC99417.1 - 0.72 10.0 5.2 1.6 8.9 1.4 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Amidase PF01425.21 EMC99418.1 - 2.8e-93 313.4 0.0 6.9e-93 312.0 0.0 1.6 1 1 0 1 1 1 1 Amidase LicD PF04991.13 EMC99420.1 - 5.9e-24 85.5 3.6 2e-18 67.4 1.1 2.2 1 1 1 2 2 2 2 LicD family HET PF06985.11 EMC99423.1 - 5.5e-16 59.2 0.4 6.7e-16 58.9 0.4 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RasGAP_C PF03836.15 EMC99424.1 - 4.8e-47 159.5 1.1 2e-46 157.5 1.1 2.2 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.19 EMC99424.1 - 1.9e-38 132.3 0.0 7.5e-38 130.3 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 EMC99424.1 - 2.7e-12 46.8 0.0 1.9e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 EMC99424.1 - 0.00011 21.6 54.9 1.1 9.2 1.2 14.7 16 0 0 16 16 16 4 IQ calmodulin-binding motif PTS_2-RNA PF01885.16 EMC99424.1 - 0.045 13.8 0.8 0.099 12.7 0.8 1.6 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Zn_clus PF00172.18 EMC99426.1 - 5.1e-08 32.9 10.6 9.3e-08 32.1 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC99426.1 - 0.0005 19.2 0.0 0.0018 17.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain SlyX PF04102.12 EMC99426.1 - 2.4 8.9 7.9 4.3 8.0 0.1 2.7 2 0 0 2 2 2 0 SlyX Thiolase_N PF00108.23 EMC99428.1 - 4.3e-14 52.5 0.2 1.9e-12 47.1 0.1 2.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMC99428.1 - 8.7e-11 41.5 0.4 7.8e-10 38.5 0.1 2.6 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EMC99428.1 - 3.1e-08 33.3 0.2 3.7e-06 26.7 0.2 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EMC99428.1 - 1.8e-05 24.5 0.5 5.1e-05 23.0 0.5 1.7 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EMC99428.1 - 0.0041 17.1 0.1 0.24 11.5 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 EMC99428.1 - 0.031 13.0 0.1 0.078 11.7 0.1 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Tim17 PF02466.19 EMC99429.1 - 0.0011 19.3 3.3 0.0028 18.0 3.2 1.7 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family RNB PF00773.19 EMC99430.1 - 2.8e-61 207.6 0.0 1.1e-60 205.7 0.0 1.9 1 1 0 1 1 1 1 RNB domain Abhydrolase_3 PF07859.13 EMC99431.1 - 6.7e-21 75.1 0.1 1.4e-19 70.8 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMC99431.1 - 4.9e-09 36.0 0.0 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EMC99431.1 - 2.2e-06 26.8 0.1 7.5e-06 25.1 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 EMC99431.1 - 2.4e-05 23.4 0.0 3.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EMC99431.1 - 3e-05 24.7 0.2 4e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EMC99431.1 - 0.00025 20.8 0.0 0.0013 18.5 0.0 2.3 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 EMC99431.1 - 0.00064 18.5 0.0 0.029 13.0 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 EMC99431.1 - 0.014 14.9 0.1 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase ThiS PF02597.20 EMC99432.1 - 3.6e-08 33.9 0.0 7.8e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 ThiS family Glyco_transf_28 PF03033.20 EMC99433.1 - 1.4e-17 64.1 0.1 3.8e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EMC99433.1 - 1e-07 31.1 0.0 1.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.20 EMC99433.1 - 1.4e-05 24.7 0.2 3.6e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif ATG_C PF09333.11 EMC99433.1 - 0.00037 20.8 0.0 0.0018 18.6 0.0 2.2 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain GXWXG PF14231.6 EMC99434.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 GXWXG protein 2_5_RNA_ligase2 PF13563.6 EMC99434.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily DZF PF07528.14 EMC99435.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 DZF domain p450 PF00067.22 EMC99437.1 - 2.6e-59 201.2 0.0 3.3e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5316 PF17247.2 EMC99438.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5316) Tudor_3 PF18115.1 EMC99439.1 - 9.5e-05 22.2 0.2 0.00019 21.2 0.2 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF1325 PF07039.11 EMC99439.1 - 0.00033 20.8 0.3 0.0006 19.9 0.3 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 EMC99439.1 - 0.0011 18.7 0.3 0.0022 17.8 0.3 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF4537 PF15057.6 EMC99439.1 - 0.0027 17.7 0.1 0.0052 16.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TUDOR PF00567.24 EMC99439.1 - 0.0043 17.1 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EMC99439.1 - 0.0069 15.7 3.4 0.0069 15.7 3.4 2.5 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) Tudor-knot PF11717.8 EMC99439.1 - 0.058 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain SAWADEE PF16719.5 EMC99439.1 - 0.16 12.0 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 SAWADEE domain PAP1 PF08601.10 EMC99441.1 - 3.9e-55 188.1 40.4 3.9e-55 188.1 40.4 3.0 2 2 1 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 EMC99441.1 - 1.4e-09 37.9 8.6 2.5e-09 37.1 8.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 EMC99441.1 - 0.018 14.7 4.5 0.037 13.8 4.5 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 EMC99441.1 - 0.071 13.2 11.3 0.36 11.0 11.0 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Nop53 PF07767.11 EMC99441.1 - 0.15 11.4 17.9 0.32 10.3 17.9 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) bZIP_Maf PF03131.17 EMC99441.1 - 0.19 12.2 10.0 0.54 10.8 10.0 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor CDC45 PF02724.14 EMC99441.1 - 4.3 5.5 13.2 9 4.5 13.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-bind_2 PF08914.11 EMC99442.1 - 1.3e-16 60.5 0.1 2.5e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 EMC99442.1 - 2.8e-09 37.2 0.0 6.3e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 EMC99442.1 - 0.00022 21.8 0.1 0.00051 20.6 0.1 1.6 1 0 0 1 1 1 1 Rap1, DNA-binding DHHC PF01529.20 EMC99443.1 - 2.3e-33 115.2 0.4 2.3e-33 115.2 0.4 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Neuropep_like PF15161.6 EMC99445.1 - 0.15 11.8 0.2 0.3 10.8 0.2 1.4 1 0 0 1 1 1 0 Neuropeptide-like adh_short_C2 PF13561.6 EMC99446.1 - 1.9e-50 171.6 3.8 2.5e-50 171.2 3.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC99446.1 - 1.8e-36 125.4 2.3 2.4e-36 125.0 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC99446.1 - 4.1e-12 46.4 1.4 5.8e-12 45.9 1.4 1.2 1 0 0 1 1 1 1 KR domain DUF1860 PF08949.10 EMC99446.1 - 0.00037 20.3 2.2 0.00046 20.0 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1860) Epimerase PF01370.21 EMC99446.1 - 0.0009 18.8 0.5 0.0021 17.6 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMC99446.1 - 0.0016 17.6 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMC99446.1 - 0.018 14.4 0.1 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EMC99446.1 - 0.079 12.8 0.7 0.13 12.2 0.7 1.4 1 0 0 1 1 1 0 NAD(P)H-binding HECT PF00632.25 EMC99447.1 - 2.9e-57 194.5 0.0 5e-57 193.7 0.0 1.4 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EMC99447.1 - 3e-16 59.4 0.7 1.4e-15 57.2 0.6 2.3 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DEAD PF00270.29 EMC99448.1 - 1.6e-40 138.7 0.0 3.7e-40 137.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMC99448.1 - 2e-28 98.9 0.0 6.1e-28 97.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC99448.1 - 3e-05 24.1 0.0 5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMC99448.1 - 0.013 15.7 0.2 0.056 13.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain UTP25 PF06862.12 EMC99448.1 - 0.015 14.1 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 RPEL PF02755.15 EMC99450.1 - 0.029 14.1 0.4 0.073 12.8 0.4 1.8 1 0 0 1 1 1 0 RPEL repeat F-box PF00646.33 EMC99450.1 - 0.038 13.9 2.8 0.038 13.9 2.8 1.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EMC99450.1 - 0.99 9.4 8.9 0.063 13.2 3.2 1.9 2 0 0 2 2 2 0 F-box-like YtfJ_HI0045 PF09695.10 EMC99453.1 - 0.51 10.0 1.8 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) LAMTOR PF15454.6 EMC99454.1 - 9e-10 39.0 0.5 2.1e-09 37.8 0.1 1.9 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator FUSC PF04632.12 EMC99454.1 - 1.3 7.5 5.0 1.5 7.3 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSP70 PF00012.20 EMC99456.1 - 2.2e-262 871.6 11.7 2.6e-262 871.4 11.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EMC99456.1 - 4.9e-20 71.6 0.6 5e-19 68.3 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EMC99456.1 - 0.017 14.1 0.3 0.25 10.3 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 EMC99456.1 - 0.077 12.7 0.0 0.59 9.8 0.0 2.3 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EMC99456.1 - 1.3 8.2 5.5 0.77 9.0 0.1 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.6 EMC99456.1 - 5.2 7.6 10.4 35 4.9 0.3 3.7 3 2 0 3 3 3 0 Cell division protein FtsA adh_short_C2 PF13561.6 EMC99459.1 - 4.9e-62 209.5 0.9 6.5e-62 209.1 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC99459.1 - 2.1e-53 180.7 1.1 2.8e-53 180.3 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC99459.1 - 1.6e-13 50.9 0.5 2.5e-13 50.4 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC99459.1 - 0.00027 20.5 0.8 0.001 18.6 0.8 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PfkB PF00294.24 EMC99459.1 - 0.034 13.4 0.3 0.064 12.5 0.3 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Polysacc_synt_2 PF02719.15 EMC99459.1 - 0.095 11.8 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DFP PF04127.15 EMC99459.1 - 0.11 12.4 0.2 0.23 11.3 0.1 1.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 EMC99459.1 - 0.16 11.3 1.6 1.3 8.3 1.6 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Asp PF00026.23 EMC99460.1 - 6.7e-36 124.3 0.6 3.4e-19 69.4 0.5 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EMC99460.1 - 2.4e-06 28.1 0.2 0.0051 17.4 0.0 3.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EMC99460.1 - 0.0017 18.9 0.1 0.54 10.9 0.0 3.3 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 EMC99460.1 - 0.018 15.3 0.3 2.2 8.5 0.3 2.7 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EMC99460.1 - 0.031 14.0 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal adh_short_C2 PF13561.6 EMC99461.1 - 2.1e-62 210.8 0.1 2.6e-62 210.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC99461.1 - 3.4e-48 163.7 0.1 4e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC99461.1 - 1.8e-06 28.0 0.3 3.6e-06 27.0 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EMC99461.1 - 0.00017 21.2 0.1 0.0015 18.1 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_1 PF00175.21 EMC99462.1 - 2.2e-14 54.0 0.0 3.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EMC99462.1 - 9e-11 42.3 0.2 2.4e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 EMC99462.1 - 1.2e-07 32.0 0.2 2.1e-05 24.7 0.0 3.0 2 1 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EMC99462.1 - 0.0024 18.2 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 EMC99462.1 - 0.01 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Protoglobin SopE_GEF PF07487.13 EMC99462.1 - 0.061 13.4 0.1 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 SopE GEF domain Malic_M PF03949.15 EMC99463.1 - 3.9e-92 308.2 0.0 5.1e-92 307.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EMC99463.1 - 2e-67 226.5 0.0 3.4e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain 6PGD PF00393.19 EMC99464.1 - 2.1e-92 309.6 0.0 2.8e-92 309.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EMC99464.1 - 5e-25 88.5 0.0 1.2e-24 87.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EMC99464.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RXLR_WY PF18634.1 EMC99464.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain Defensin_1 PF00323.19 EMC99464.1 - 0.19 12.4 0.6 0.43 11.2 0.6 1.6 1 0 0 1 1 1 0 Mammalian defensin Pex2_Pex12 PF04757.14 EMC99465.1 - 3.6e-36 124.9 2.0 4.8e-36 124.5 2.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EMC99465.1 - 0.0015 18.6 4.4 0.003 17.7 4.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EMC99465.1 - 0.23 11.5 2.8 0.8 9.8 2.8 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EMC99466.1 - 2.2 8.1 13.4 9.3 6.1 13.4 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Abhydrolase_3 PF07859.13 EMC99467.1 - 2.6e-50 171.2 0.0 3.2e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMC99467.1 - 0.0092 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EMC99467.1 - 0.022 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase IBN_N PF03810.19 EMC99470.1 - 2.8e-11 43.2 0.3 1.2e-10 41.1 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EMC99470.1 - 0.00073 19.6 3.4 0.0023 18.0 0.2 3.2 4 0 0 4 4 4 1 Exportin 1-like protein Propeptide_C25 PF08126.11 EMC99470.1 - 0.024 13.7 0.1 0.043 12.9 0.1 1.3 1 0 0 1 1 1 0 Propeptide_C25 F-box-like_2 PF13013.6 EMC99471.1 - 0.049 13.6 0.0 0.08 12.9 0.0 1.5 1 1 0 1 1 1 0 F-box-like domain tRNA-synt_2d PF01409.20 EMC99472.1 - 7.2e-82 274.5 0.0 1.1e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EMC99472.1 - 1.3e-13 51.0 0.1 2.7e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EMC99472.1 - 1.5e-07 31.1 0.0 0.00068 19.1 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EMC99472.1 - 2.6e-05 23.5 0.1 0.0035 16.5 0.0 3.2 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EMC99472.1 - 0.0023 17.9 0.0 0.0075 16.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Rio2_N PF09202.11 EMC99472.1 - 0.093 13.0 0.1 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Rio2, N-terminal ADH_N PF08240.12 EMC99473.1 - 4.5e-23 81.2 5.0 6.9e-23 80.6 5.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC99473.1 - 2.6e-18 66.3 0.0 3.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMC99473.1 - 8.6e-10 39.8 0.0 1.5e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMC99473.1 - 0.00013 21.4 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EMC99473.1 - 0.0017 17.7 0.1 0.0028 17.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3431 PF11913.8 EMC99475.1 - 1.1e-78 264.0 0.0 1.3e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) VWA_2 PF13519.6 EMC99476.1 - 0.0052 17.4 0.0 0.014 16.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EMC99476.1 - 0.019 15.3 0.0 0.065 13.5 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain Fungal_trans_2 PF11951.8 EMC99477.1 - 8.4e-13 47.9 0.1 8.9e-13 47.8 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.7 EMC99478.1 - 0.0013 18.6 0.4 0.0024 17.7 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC99478.1 - 0.0049 16.7 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain CTP_transf_like PF01467.26 EMC99480.1 - 1.4e-24 86.9 0.0 1.8e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Glyco_hydro_10 PF00331.20 EMC99481.1 - 7.3e-93 311.2 0.5 8.4e-93 311.0 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Bac_rhamnosid6H PF17389.2 EMC99481.1 - 0.012 14.9 0.2 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Esterase_phd PF10503.9 EMC99482.1 - 2.8e-24 85.9 0.6 3.8e-24 85.4 0.6 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EMC99482.1 - 1.6e-08 34.3 1.2 2.2e-08 33.9 1.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF5020 PF16412.5 EMC99482.1 - 0.0023 17.8 1.1 0.28 11.0 0.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5020) Esterase PF00756.20 EMC99482.1 - 0.0032 17.2 1.1 0.0052 16.5 1.1 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EMC99482.1 - 0.044 13.4 0.9 0.067 12.8 0.6 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EMC99482.1 - 0.052 13.4 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EMC99482.1 - 0.092 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 EMC99482.1 - 0.12 11.9 1.4 0.36 10.4 1.4 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Img2 PF05046.14 EMC99484.1 - 0.04 14.2 0.0 0.06 13.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Glyoxalase PF00903.25 EMC99485.1 - 3.4e-40 137.2 0.2 4.6e-19 68.9 0.2 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMC99485.1 - 4.2e-14 52.7 0.1 5.7e-06 26.6 0.0 4.1 3 2 1 4 4 4 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EMC99485.1 - 7.4e-08 33.1 0.0 0.001 19.8 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EMC99485.1 - 9.9e-08 32.3 0.0 0.045 13.9 0.0 3.2 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EMC99485.1 - 0.00033 20.6 0.3 6.1 6.8 0.0 4.1 4 1 0 4 4 4 1 Glyoxalase-like domain DUF1338 PF07063.13 EMC99485.1 - 0.0051 16.0 0.1 3.6 6.7 0.2 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF1338) MoaF PF10703.9 EMC99485.1 - 0.014 15.3 0.6 2.3 8.2 0.0 2.8 3 0 0 3 3 3 0 MoaF N-terminal domain CppA_N PF14506.6 EMC99485.1 - 0.023 14.8 0.2 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal PRT_C PF08372.10 EMC99485.1 - 0.024 14.4 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal HTH_54 PF18607.1 EMC99485.1 - 0.092 12.8 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 ParA helix turn helix domain PP_M1 PF03012.14 EMC99485.1 - 0.16 11.5 0.0 0.56 9.7 0.0 1.8 3 0 0 3 3 3 0 Phosphoprotein TMEM239 PF15841.5 EMC99488.1 - 0.4 10.6 5.7 0.63 9.9 5.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 239 family Cu-oxidase_3 PF07732.15 EMC99490.1 - 3.5e-40 136.7 1.5 3.5e-40 136.7 1.5 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EMC99490.1 - 4.1e-38 131.0 0.8 1e-37 129.7 0.8 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMC99490.1 - 2.2e-37 127.9 6.9 5.1e-33 113.7 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cupin_5 PF06172.11 EMC99491.1 - 3.1e-50 170.0 0.0 4.1e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Copper-fist PF00649.18 EMC99492.1 - 1.3e-17 63.0 1.8 1.3e-17 63.0 1.8 2.4 2 1 1 3 3 3 1 Copper fist DNA binding domain Glyco_hydro_cc PF11790.8 EMC99493.1 - 8.7e-59 199.0 0.1 9.6e-59 198.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF3997 PF13162.6 EMC99494.1 - 0.16 12.3 0.1 0.22 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) Glyco_hydro_18 PF00704.28 EMC99495.1 - 4.6e-17 62.7 0.0 1.3e-16 61.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 UBA PF00627.31 EMC99495.1 - 1.1e-06 28.4 0.0 4.2e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain RuvA_C PF07499.13 EMC99495.1 - 0.23 11.9 0.1 0.44 11.1 0.1 1.4 1 0 0 1 1 1 0 RuvA, C-terminal domain MBOAT_2 PF13813.6 EMC99496.1 - 5.4e-09 36.2 5.9 1.1e-08 35.2 5.9 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Aldose_epim PF01263.20 EMC99497.1 - 7.4e-41 140.4 0.0 9e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.8 EMC99498.1 - 4.1e-128 427.6 2.2 4.1e-128 427.6 2.2 1.5 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 EMC99499.1 - 1e-122 410.5 0.1 1.2e-122 410.3 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn ADH_zinc_N PF00107.26 EMC99500.1 - 4e-23 81.8 1.5 6.5e-23 81.1 1.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC99500.1 - 1.4e-18 66.8 0.5 1.4e-18 66.8 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMC99500.1 - 1.6e-05 26.0 0.0 3.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMC99500.1 - 0.00063 19.1 2.0 0.0011 18.3 2.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EMC99500.1 - 0.002 17.7 0.9 0.0032 17.0 0.9 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus adh_short PF00106.25 EMC99500.1 - 0.005 16.3 1.9 0.0091 15.5 1.9 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EMC99500.1 - 0.01 15.3 0.2 0.015 14.8 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.13 EMC99501.1 - 2.4e-14 53.7 0.1 3.4e-12 46.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Nexin_C PF08628.12 EMC99502.1 - 0.039 14.5 0.3 0.039 14.5 0.3 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal TFIIA PF03153.13 EMC99502.1 - 3.9 7.4 22.9 4.9 7.0 22.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pantoate_transf PF02548.15 EMC99503.1 - 8.6e-109 362.9 1.7 1e-108 362.7 1.7 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EMC99503.1 - 7.4e-08 32.1 0.4 7.4e-08 32.1 0.4 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 EMC99503.1 - 0.018 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) APG12 PF04110.13 EMC99504.1 - 9e-28 96.5 0.0 1.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EMC99504.1 - 0.018 15.3 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Dfp1_Him1_M PF08630.10 EMC99505.1 - 3.5e-40 137.1 0.0 3.5e-40 137.1 0.0 2.5 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 EMC99505.1 - 4.8e-20 71.4 0.9 7.7e-20 70.7 0.9 1.3 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 EMC99505.1 - 0.0083 16.0 0.0 0.034 14.1 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain Peptidase_C14 PF00656.22 EMC99506.1 - 1.9e-44 152.5 0.0 2.5e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Atx10homo_assoc PF09759.9 EMC99507.1 - 5.7e-23 80.8 0.3 2.3e-22 78.9 0.3 2.0 1 1 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain PPP4R2 PF09184.11 EMC99507.1 - 2.7 7.5 8.0 5.7 6.4 8.0 1.5 1 0 0 1 1 1 0 PPP4R2 Astro_capsid_p PF12226.8 EMC99507.1 - 4.9 6.2 8.5 8.9 5.4 8.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 EMC99507.1 - 8.3 4.5 8.9 12 4.0 7.8 1.7 2 0 0 2 2 2 0 Nop14-like family Beta-lactamase PF00144.24 EMC99508.1 - 8.1e-37 127.2 0.1 1.2e-36 126.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EMC99508.1 - 0.0042 16.7 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase enzyme family Inositol_P PF00459.25 EMC99509.1 - 4.1e-53 180.7 0.4 1.4e-52 178.9 0.4 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family LUC7 PF03194.15 EMC99510.1 - 8.6e-67 225.4 0.6 1e-66 225.2 0.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DASH_Duo1 PF08651.10 EMC99510.1 - 0.02 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 MCPsignal PF00015.21 EMC99510.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Gpi16 PF04113.14 EMC99511.1 - 5.5e-202 672.1 0.0 6.8e-202 671.8 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Cyt-b5 PF00173.28 EMC99512.1 - 8.1e-21 74.0 0.1 1.1e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF347 PF03988.12 EMC99512.1 - 0.0053 16.9 0.0 0.007 16.5 0.0 1.2 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) DUF4366 PF14283.6 EMC99512.1 - 0.08 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) VHS PF00790.19 EMC99513.1 - 5.3e-32 110.6 0.2 8.4e-32 110.0 0.2 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EMC99513.1 - 3.4e-16 58.6 0.0 6.6e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EMC99513.1 - 7.6e-13 48.1 0.1 1.4e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EMC99513.1 - 2.2e-12 46.5 0.0 4.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EMC99513.1 - 2.9e-09 37.1 0.2 8.8e-09 35.6 0.1 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EMC99513.1 - 0.014 15.3 3.2 0.037 13.9 3.2 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Pkinase PF00069.25 EMC99514.1 - 4.8e-72 242.5 0.0 7.4e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC99514.1 - 7.4e-46 156.5 0.0 1.3e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EMC99514.1 - 1.4e-22 79.8 0.1 4.5e-22 78.2 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EMC99514.1 - 1.6e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMC99514.1 - 2.3e-05 23.3 1.3 5.1e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EMC99514.1 - 0.042 13.8 0.0 0.72 9.7 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMC99514.1 - 0.068 12.1 0.7 0.44 9.4 0.7 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EMC99514.1 - 0.13 11.6 0.3 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med13_C PF06333.12 EMC99515.1 - 4.1e-84 282.7 0.3 1.8e-83 280.5 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 EMC99515.1 - 1.1e-33 117.1 2.2 4e-17 62.8 0.4 2.7 2 1 1 3 3 3 2 MID domain of medPIWI Med13_N PF11597.8 EMC99515.1 - 3.7e-26 92.3 0.0 6e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.12 EMC99516.1 - 5.4e-12 45.3 4.2 1.1e-11 44.3 4.2 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EMC99516.1 - 0.00025 21.8 0.4 3 8.9 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat MARVEL PF01284.23 EMC99518.1 - 0.043 13.8 13.6 0.23 11.5 8.3 2.1 1 1 1 2 2 2 0 Membrane-associating domain WD40 PF00400.32 EMC99519.1 - 1.1e-10 41.8 9.4 0.00039 21.2 0.2 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC99519.1 - 4.7e-07 30.0 0.1 0.0053 17.0 0.0 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 PF17120.5 EMC99519.1 - 8.3e-07 28.5 9.4 1.7e-06 27.5 9.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type eIF2A PF08662.11 EMC99519.1 - 2.2e-06 27.7 0.0 1.6e-05 24.9 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.6 EMC99519.1 - 0.0041 17.4 2.8 0.0096 16.2 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EMC99519.1 - 0.0075 16.5 0.6 0.018 15.3 0.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Nebulin PF00880.18 EMC99519.1 - 0.51 10.3 2.5 24 4.9 0.1 2.7 2 0 0 2 2 2 0 Nebulin repeat zinc_ribbon_16 PF17034.5 EMC99519.1 - 0.6 10.3 5.2 0.16 12.2 1.5 2.0 2 0 0 2 2 2 0 Zinc-ribbon like family XLF PF09302.11 EMC99520.1 - 2e-49 168.2 0.1 3.1e-49 167.6 0.1 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component IDEAL PF08858.10 EMC99520.1 - 3.3 7.5 13.7 0.31 10.8 0.9 2.8 3 0 0 3 3 3 0 IDEAL domain CactinC_cactus PF09732.9 EMC99521.1 - 6.2e-56 187.7 1.9 8.8e-56 187.2 1.9 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 EMC99521.1 - 1.5e-55 188.0 1.1 2.1e-55 187.5 1.1 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin SF3A2 PF16835.5 EMC99521.1 - 0.0098 16.2 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 EMC99521.1 - 0.043 13.9 1.4 0.064 13.3 0.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Forkhead PF00250.18 EMC99522.1 - 7.7e-21 74.1 0.4 2.2e-20 72.7 0.1 1.9 2 0 0 2 2 2 1 Forkhead domain ER_lumen_recept PF00810.18 EMC99523.1 - 7.7e-39 133.9 9.5 1.1e-38 133.3 9.5 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EMC99523.1 - 0.0095 15.7 2.7 0.033 14.0 0.1 3.0 3 0 0 3 3 3 1 PQ loop repeat MFS_1 PF07690.16 EMC99524.1 - 3.8e-31 108.3 29.2 3.8e-31 108.3 29.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC99524.1 - 2.7e-14 52.9 6.2 2.7e-14 52.9 6.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMC99524.1 - 1.7e-05 23.4 4.0 3e-05 22.7 4.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldedh PF00171.22 EMC99525.1 - 9.1e-10 37.6 0.0 0.00078 18.1 0.0 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family FAA_hydrolase PF01557.18 EMC99527.1 - 1.2e-52 178.7 0.0 1.6e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EMC99527.1 - 2.3e-17 63.1 0.0 3.7e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Cupin_2 PF07883.11 EMC99528.1 - 1.4e-11 43.9 0.0 2.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EMC99528.1 - 0.0045 16.6 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EMC99528.1 - 0.0093 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Cupin zf-C2H2 PF00096.26 EMC99529.1 - 6.5e-10 38.9 13.2 1.6e-05 25.1 0.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 EMC99529.1 - 9.9e-10 37.9 0.4 2.1e-09 36.8 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EMC99529.1 - 1.8e-06 28.1 6.4 2.3e-06 27.7 1.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.18 EMC99529.1 - 4.4e-06 26.7 14.9 8.7e-06 25.8 14.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EMC99529.1 - 1.1e-05 25.9 16.2 0.0054 17.5 0.1 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EMC99529.1 - 2.9e-05 23.9 7.3 0.071 13.1 3.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMC99529.1 - 0.0022 18.2 1.3 1.4 9.3 1.2 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC99529.1 - 0.032 14.6 2.6 2.5 8.6 1.6 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 EMC99529.1 - 0.05 13.9 0.2 0.62 10.4 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 EMC99529.1 - 0.87 9.4 11.7 0.93 9.3 0.0 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Peptidase_S15 PF02129.18 EMC99530.1 - 5.7e-45 154.0 1.3 8.2e-45 153.5 1.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EMC99530.1 - 8.9e-44 150.1 0.7 1.3e-43 149.6 0.7 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 EMC99530.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 EMC99531.1 - 2.2e-20 73.2 1.1 5.9e-20 71.8 0.4 2.0 2 1 0 2 2 2 1 FAD binding domain ADC PF06314.11 EMC99531.1 - 1.5e-13 50.9 0.0 3.7e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 EMC99531.1 - 1.1e-07 32.0 0.4 2.7e-07 30.7 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMC99531.1 - 1.9e-05 23.9 0.7 4.3e-05 22.8 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC99531.1 - 2.1e-05 23.9 2.9 0.00018 20.9 2.9 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMC99531.1 - 0.00024 20.8 1.4 0.00054 19.6 1.3 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EMC99531.1 - 0.00082 18.6 0.7 0.0014 17.8 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EMC99531.1 - 0.0017 17.7 0.3 0.008 15.5 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EMC99531.1 - 0.002 17.1 0.2 0.039 12.8 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 EMC99531.1 - 0.0058 16.0 1.1 0.0091 15.4 1.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMC99531.1 - 0.0063 15.6 1.4 0.034 13.2 1.4 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EMC99531.1 - 0.01 14.6 2.0 0.024 13.3 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 EMC99531.1 - 0.013 14.9 0.1 0.35 10.1 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EMC99531.1 - 0.016 15.7 0.1 0.038 14.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMC99531.1 - 0.016 14.4 0.4 0.12 11.7 0.1 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMC99531.1 - 0.038 13.2 0.0 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family LigB PF02900.18 EMC99532.1 - 4.4e-12 45.6 0.0 5.3e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Ribosomal_S19e PF01090.19 EMC99534.1 - 1.8e-58 196.1 0.3 2e-58 196.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e GPI-anchored PF10342.9 EMC99535.1 - 3.5e-21 75.8 0.6 5.8e-21 75.1 0.6 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cellulase PF00150.18 EMC99538.1 - 1e-11 44.9 1.9 3.9e-11 42.9 0.1 2.3 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EMC99538.1 - 0.025 13.9 0.0 0.093 12.1 0.0 1.9 1 1 0 1 1 1 0 Beta-galactosidase Aldo_ket_red PF00248.21 EMC99539.1 - 5.5e-40 137.4 0.0 9.1e-38 130.1 0.0 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family DUF2744 PF10910.8 EMC99539.1 - 0.018 15.0 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) Antimicrobial18 PF08130.11 EMC99539.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Type A lantibiotic family eRF1_1 PF03463.15 EMC99540.1 - 1.9e-51 173.4 0.1 3.5e-51 172.6 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EMC99540.1 - 3e-21 76.0 0.0 5.6e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EMC99540.1 - 4.5e-20 72.3 0.0 6.8e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Ribonuc_L-PSP PF01042.21 EMC99542.1 - 1.5e-40 138.0 0.0 1.7e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ILVD_EDD PF00920.21 EMC99543.1 - 1.3e-210 700.4 1.6 1.5e-210 700.2 1.6 1.0 1 0 0 1 1 1 1 Dehydratase family Phage_BR0599 PF09356.10 EMC99543.1 - 0.036 14.4 0.4 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Phage conserved hypothetical protein BR0599 Radical_SAM PF04055.21 EMC99544.1 - 0.00039 20.8 0.0 0.0006 20.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EMC99544.1 - 0.0029 17.9 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EMC99544.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Abhydrolase_6 PF12697.7 EMC99545.1 - 4.9e-15 56.7 1.6 5.9e-15 56.5 1.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMC99545.1 - 8.7e-09 35.4 0.1 2e-07 30.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC99545.1 - 4.1e-07 29.5 0.0 0.00032 20.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF2462 PF09495.10 EMC99546.1 - 1.4e-18 67.4 17.4 1.4e-18 67.4 17.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Glyco_hydro_115 PF15979.5 EMC99548.1 - 2.7e-139 464.4 0.1 4.6e-139 463.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EMC99548.1 - 4.4e-53 179.6 0.1 1.2e-52 178.2 0.1 1.8 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain FMN_dh PF01070.18 EMC99551.1 - 6.2e-120 400.4 0.0 7.2e-120 400.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EMC99551.1 - 2.4e-07 30.1 0.7 2.4e-06 26.8 0.3 2.2 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EMC99551.1 - 2.1e-06 27.1 0.2 7e-06 25.4 0.2 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EMC99551.1 - 0.00046 19.7 0.1 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EMC99551.1 - 0.046 13.0 0.3 3.8 6.8 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 EMC99551.1 - 0.14 11.6 0.9 0.22 10.9 0.9 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Alanine_zipper PF11839.8 EMC99552.1 - 0.18 12.2 9.5 0.28 11.6 9.5 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein TENA_THI-4 PF03070.16 EMC99553.1 - 0.037 13.8 0.0 0.33 10.7 0.0 2.1 1 1 0 1 1 1 0 TENA/THI-4/PQQC family zf-BED PF02892.15 EMC99553.1 - 0.042 13.9 0.7 0.1 12.6 0.7 1.6 1 0 0 1 1 1 0 BED zinc finger HrpB2 PF09487.10 EMC99553.1 - 0.048 14.1 0.3 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Transp_cyt_pur PF02133.15 EMC99554.1 - 2e-20 73.0 40.7 3.7e-20 72.1 40.6 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5453 PF17534.2 EMC99554.1 - 0.96 9.4 4.5 0.3 11.0 0.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5453) F-box-like PF12937.7 EMC99555.1 - 2.7e-08 33.6 0.2 5.6e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC99555.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 F-box domain Tyrosinase PF00264.20 EMC99557.1 - 2.8e-37 129.2 0.0 4e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.19 EMC99559.1 - 1.5e-12 47.4 0.0 2.5e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMC99559.1 - 2.3e-07 30.3 0.2 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC99559.1 - 0.00024 21.2 0.0 0.00074 19.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC99559.1 - 0.00049 19.8 0.0 0.00096 18.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EMC99559.1 - 0.0009 18.2 0.3 0.18 10.6 0.1 2.4 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 EMC99559.1 - 0.0087 16.6 0.6 4.6 7.9 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC99559.1 - 0.049 13.6 0.0 0.19 11.7 0.0 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EMC99559.1 - 0.18 11.0 1.4 7.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC99559.1 - 0.2 10.7 0.4 0.31 10.1 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain MARVEL PF01284.23 EMC99562.1 - 0.027 14.5 12.6 0.11 12.5 12.3 1.8 1 1 1 2 2 2 0 Membrane-associating domain TMEM70 PF06979.12 EMC99562.1 - 0.84 10.1 3.9 1.8 9.0 3.9 1.5 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex Oxidored_FMN PF00724.20 EMC99563.1 - 1.9e-63 214.8 0.0 2.3e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EMC99563.1 - 0.041 13.0 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF1275 PF06912.11 EMC99565.1 - 3e-45 154.5 14.1 3.7e-45 154.2 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) GTP_EFTU PF00009.27 EMC99566.1 - 4.2e-43 147.2 0.0 8.2e-43 146.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMC99566.1 - 4.5e-30 104.2 0.1 1.2e-29 102.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMC99566.1 - 8.5e-05 22.9 0.2 0.0002 21.7 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMC99566.1 - 0.00042 20.4 0.1 0.002 18.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ran-binding PF05508.11 EMC99567.1 - 3e-121 404.2 0.0 3.9e-121 403.8 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Hid1 PF12722.7 EMC99567.1 - 0.16 10.1 0.6 0.26 9.4 0.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CorA PF01544.18 EMC99567.1 - 0.27 10.5 2.5 0.43 9.9 2.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein His_Phos_1 PF00300.22 EMC99568.1 - 4.3e-16 59.2 0.1 5.9e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_42 PF02449.15 EMC99568.1 - 0.018 14.4 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Tam41_Mmp37 PF09139.11 EMC99568.1 - 0.17 11.3 0.5 0.34 10.3 0.2 1.5 1 1 1 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial COX15-CtaA PF02628.15 EMC99569.1 - 3.9e-110 368.0 8.7 5.1e-110 367.6 8.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein FAD_binding_1 PF00667.20 EMC99570.1 - 8.4e-61 205.4 0.0 1.4e-60 204.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 EMC99570.1 - 7.1e-14 52.3 0.0 1.8e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 EMC99570.1 - 3.1e-09 37.4 0.0 8.9e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 EMC99570.1 - 1.5e-07 31.7 0.2 4e-07 30.3 0.2 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 EMC99570.1 - 2.3e-05 24.3 0.2 7.6e-05 22.6 0.2 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.24 EMC99570.1 - 0.18 12.2 0.0 12 6.4 0.0 3.2 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain PTPA PF03095.15 EMC99572.1 - 4e-114 381.1 0.0 4.9e-114 380.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein AT_hook PF02178.19 EMC99573.1 - 0.013 15.3 2.1 0.046 13.6 2.1 2.1 1 0 0 1 1 1 0 AT hook motif Pap_E4 PF02711.14 EMC99574.1 - 8.7 7.4 9.8 4.1 8.4 6.6 2.2 2 0 0 2 2 2 0 E4 protein MFS_1 PF07690.16 EMC99575.1 - 1.6e-12 47.0 43.2 4.1e-07 29.2 21.2 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily UcrQ PF02939.16 EMC99575.1 - 0.054 13.4 0.4 9.4 6.2 0.0 2.8 2 0 0 2 2 2 0 UcrQ family PY_rept_46 PF09689.10 EMC99576.1 - 0.018 15.6 0.2 0.033 14.7 0.2 1.4 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) DUF1771 PF08590.10 EMC99578.1 - 0.0044 17.4 16.3 0.0044 17.4 16.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EMC99578.1 - 0.057 13.8 0.2 0.3 11.5 0.1 2.2 2 0 0 2 2 2 0 Smr domain KH_1 PF00013.29 EMC99579.1 - 5.5e-96 314.4 27.8 2.5e-13 49.6 0.4 12.8 14 1 0 14 14 14 9 KH domain SLS PF14611.6 EMC99579.1 - 3.1e-20 73.0 2.2 3.4e-05 23.8 0.0 6.4 4 2 2 6 6 6 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EMC99579.1 - 2.9e-11 43.0 14.3 0.025 14.4 0.4 7.5 7 0 0 7 7 7 3 KH domain KH_4 PF13083.6 EMC99579.1 - 9.2e-05 22.2 6.2 1.1 9.2 0.0 5.9 7 0 0 7 7 7 1 KH domain YqgF PF14639.6 EMC99579.1 - 0.019 14.8 0.6 7.7 6.3 0.0 3.6 3 0 0 3 3 3 0 Holliday-junction resolvase-like of SPT6 KH_5 PF13184.6 EMC99579.1 - 0.088 12.9 9.0 1.8 8.7 0.5 4.6 5 0 0 5 5 5 0 NusA-like KH domain Siva PF05458.12 EMC99579.1 - 0.13 11.9 1.1 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Mito_carr PF00153.27 EMC99581.1 - 2e-52 175.1 2.5 9.3e-19 67.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMC99581.1 - 0.014 14.5 1.0 0.096 11.8 0.9 2.4 1 1 0 1 1 1 0 Gammaproteobacterial serine protease zf-Nse PF11789.8 EMC99582.1 - 9.3e-24 83.0 0.6 1.5e-23 82.3 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EMC99582.1 - 4.8e-06 26.5 0.2 9.2e-06 25.6 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMC99582.1 - 0.00037 20.3 1.7 0.00067 19.4 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EMC99582.1 - 0.0029 17.3 0.7 0.0049 16.6 0.7 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 EMC99582.1 - 0.0098 15.9 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EMC99582.1 - 0.011 16.0 0.3 0.023 15.0 0.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EMC99582.1 - 0.011 15.6 0.2 0.022 14.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC99582.1 - 0.018 15.4 1.2 0.03 14.6 1.2 1.4 1 0 0 1 1 1 0 Ring finger domain Codanin-1_C PF15296.6 EMC99582.1 - 0.27 11.3 3.1 3.7 7.6 0.5 2.5 2 0 0 2 2 2 0 Codanin-1 C-terminus Shisa PF13908.6 EMC99583.1 - 0.19 12.0 10.4 5.9 7.1 0.1 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 EMC99583.1 - 0.29 11.0 4.0 2 8.3 4.0 2.2 1 1 0 1 1 1 0 TMEM154 protein family zf-RING_2 PF13639.6 EMC99584.1 - 4.6e-09 36.5 4.2 6.7e-09 35.9 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EMC99584.1 - 2.7e-06 27.5 4.4 9.5e-06 25.8 4.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EMC99584.1 - 0.00031 20.7 0.9 0.00047 20.2 0.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EMC99584.1 - 0.00063 19.7 7.8 0.001 19.0 7.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EMC99584.1 - 0.0099 15.7 6.7 0.043 13.7 6.8 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMC99584.1 - 0.019 14.7 3.7 0.029 14.1 3.7 1.3 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 EMC99584.1 - 0.034 14.0 3.4 0.056 13.3 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMC99584.1 - 0.055 13.3 1.8 0.22 11.4 1.6 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMC99584.1 - 0.12 12.4 0.9 0.19 11.7 0.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EMC99584.1 - 0.32 10.9 6.1 1.8 8.5 0.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FtsJ PF01728.19 EMC99585.1 - 2e-62 210.4 0.0 2.6e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MFS_1 PF07690.16 EMC99586.1 - 2.8e-34 118.6 54.4 3.7e-32 111.6 54.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC99586.1 - 5.1e-06 25.2 24.6 6.7e-06 24.8 24.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 EMC99586.1 - 0.12 12.5 0.2 0.12 12.5 0.2 3.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Syndecan PF01034.20 EMC99586.1 - 4.4 7.3 7.7 2.1 8.3 0.0 3.9 4 0 0 4 4 4 0 Syndecan domain Sporozoite_P67 PF05642.11 EMC99587.1 - 1.9 6.4 8.5 2.2 6.3 8.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SIS PF01380.22 EMC99589.1 - 3.3e-10 39.9 0.3 2.5e-09 37.1 0.3 2.0 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 EMC99589.1 - 5.8e-07 29.6 0.4 0.00013 22.0 0.4 2.3 1 1 1 2 2 2 2 SIS domain ARID PF01388.21 EMC99591.1 - 8e-19 68.1 0.3 2.3e-18 66.6 0.3 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BNIP2 PF12496.8 EMC99591.1 - 0.078 13.4 0.1 1.9 8.9 0.0 2.9 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Dyp_perox PF04261.12 EMC99592.1 - 2.4e-17 62.9 0.0 4.2e-16 58.8 0.0 2.4 2 1 0 2 2 2 1 Dyp-type peroxidase family Ammonium_transp PF00909.21 EMC99594.1 - 2.5e-86 289.9 33.5 2.8e-86 289.7 33.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MFS_1 PF07690.16 EMC99595.1 - 6.7e-42 143.7 33.6 1.9e-41 142.2 9.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC99595.1 - 1.7e-07 30.5 1.6 1.7e-07 30.5 1.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EMC99595.1 - 0.0054 15.6 8.0 0.13 11.1 0.1 2.6 2 1 1 3 3 3 3 MFS_1 like family Glyco_hydro_28 PF00295.17 EMC99596.1 - 6.6e-53 179.9 14.5 9.2e-53 179.4 14.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 cNMP_binding PF00027.29 EMC99597.1 - 4.4e-31 106.8 0.0 5.7e-18 64.8 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 EMC99597.1 - 1.3e-24 87.4 8.7 4e-24 85.9 8.7 1.9 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein LRR_4 PF12799.7 EMC99597.1 - 1.7e-09 37.8 0.6 0.2 12.1 0.1 7.0 5 2 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EMC99597.1 - 2.2e-09 36.6 7.0 2.5 8.4 0.0 9.0 10 0 0 10 10 10 2 Leucine Rich repeat F-box-like PF12937.7 EMC99597.1 - 1.7e-05 24.6 1.0 5.1e-05 23.1 0.3 2.2 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 EMC99597.1 - 6.3e-05 23.0 10.2 49 5.0 0.5 8.8 8 1 1 9 9 9 0 Leucine Rich Repeat F-box PF00646.33 EMC99597.1 - 0.00011 22.0 0.3 0.00011 22.0 0.3 3.6 5 0 0 5 5 5 1 F-box domain DUF5456 PF17539.2 EMC99598.1 - 0.054 13.4 0.2 0.056 13.3 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5456) MJ1316 PF04457.12 EMC99599.1 - 2.8e-12 47.2 0.4 5.5e-12 46.3 0.4 1.5 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Metallophos PF00149.28 EMC99600.1 - 8e-06 26.5 0.1 1.1e-05 26.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PAN_4 PF14295.6 EMC99601.1 - 6.7e-11 41.9 58.2 0.16 11.9 0.6 10.9 10 0 0 10 10 10 10 PAN domain PAN_3 PF08277.12 EMC99601.1 - 0.0049 16.7 53.9 0.11 12.3 0.5 10.2 9 0 0 9 9 9 5 PAN-like domain Peptidase_M20 PF01546.28 EMC99603.1 - 1.1e-22 80.8 0.0 1.9e-21 76.8 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EMC99603.1 - 3.1e-13 50.0 1.6 0.017 16.0 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 EMC99603.1 - 2.8e-06 27.2 0.0 5.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 EMC99603.1 - 0.0031 17.8 0.0 0.52 10.7 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 EMC99603.1 - 0.18 11.1 0.0 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region PQQ_3 PF13570.6 EMC99603.1 - 0.19 12.2 0.9 13 6.4 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain SelR PF01641.18 EMC99604.1 - 4.8e-52 175.1 0.4 6.2e-52 174.8 0.4 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 EMC99604.1 - 0.0021 17.8 0.1 0.36 10.6 0.0 2.3 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein GFA PF04828.14 EMC99604.1 - 0.011 16.0 1.0 0.38 11.1 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 EMC99604.1 - 0.045 14.0 0.4 0.099 12.9 0.4 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MCM_OB PF17207.3 EMC99604.1 - 0.11 12.4 0.3 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 MCM OB domain TF_Zn_Ribbon PF08271.12 EMC99604.1 - 0.23 11.0 1.2 0.52 9.9 0.2 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 EMC99604.1 - 0.82 9.8 5.1 10 6.3 5.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.6 EMC99604.1 - 1.8 8.7 4.0 5.2 7.3 1.1 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 EMC99604.1 - 3.9 7.0 6.1 3.6 7.1 0.1 2.9 4 0 0 4 4 4 0 zinc-ribbon domain MS_channel PF00924.18 EMC99605.1 - 7e-14 51.9 0.2 1.4e-13 50.9 0.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EMC99605.1 - 0.0014 18.0 0.5 0.007 15.8 0.0 2.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EMC99605.1 - 0.0042 17.5 0.0 0.022 15.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EMC99605.1 - 0.0098 15.8 0.1 0.076 13.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain Cullin PF00888.22 EMC99605.1 - 0.018 13.6 1.2 0.33 9.5 0.6 2.6 3 0 0 3 3 3 0 Cullin family EF-hand_8 PF13833.6 EMC99605.1 - 0.032 14.1 0.1 0.094 12.6 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 EMC99605.1 - 0.052 13.1 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 EF hand DUF3176 PF11374.8 EMC99606.1 - 4.8e-18 65.3 4.3 1.1e-17 64.2 4.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Methyltransf_23 PF13489.6 EMC99607.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC99607.1 - 0.0039 17.8 0.0 0.026 15.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC99607.1 - 0.005 17.6 0.0 0.021 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMC99607.1 - 0.0063 17.2 0.0 0.024 15.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Sun2_CC2 PF18580.1 EMC99607.1 - 0.066 13.4 0.5 0.13 12.5 0.4 1.6 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Amidase PF01425.21 EMC99608.1 - 3.5e-99 332.8 0.0 4.3e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.19 EMC99609.1 - 4.3e-70 236.7 0.0 5.9e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EMC99609.1 - 1.6e-45 155.2 0.0 3.9e-45 153.9 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.17 EMC99609.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EMC99609.1 - 0.087 12.0 0.1 0.47 9.6 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2OG-FeII_Oxy_2 PF13532.6 EMC99612.1 - 1.1e-30 107.3 0.0 3.6e-30 105.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.11 EMC99613.1 - 1.2e-27 97.1 0.1 1.4e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Helicase_C PF00271.31 EMC99614.1 - 6.6e-17 61.9 0.0 1.3e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DZR PF12773.7 EMC99614.1 - 0.087 12.9 0.9 0.21 11.7 0.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon PNP_UDP_1 PF01048.20 EMC99615.1 - 1.2e-38 132.7 0.0 1.5e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Sugar_tr PF00083.24 EMC99616.1 - 9.1e-33 113.8 29.2 8.7e-20 71.0 11.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EMC99616.1 - 7.8e-11 41.5 44.7 2.2e-10 40.0 42.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 EMC99617.1 - 4e-41 141.1 1.4 4.8e-41 140.9 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC99617.1 - 2.8e-37 128.1 0.1 3.6e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC99617.1 - 1.4e-10 41.4 1.4 5.2e-10 39.5 1.4 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMC99617.1 - 0.00017 21.2 0.1 0.00041 19.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMC99617.1 - 0.00034 19.8 0.1 0.0005 19.3 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 EMC99617.1 - 0.00086 18.8 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EMC99617.1 - 0.0036 17.2 0.1 0.006 16.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC99617.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family ThiF PF00899.21 EMC99617.1 - 0.25 10.7 0.7 1.1 8.6 0.2 2.0 2 0 0 2 2 2 0 ThiF family GTP_EFTU PF00009.27 EMC99618.1 - 3.7e-48 163.7 0.0 6.9e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EMC99618.1 - 6.5e-20 71.2 1.7 1.6e-19 69.9 1.7 1.7 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 EMC99618.1 - 2e-07 31.1 0.0 0.00047 20.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EMC99618.1 - 3.6e-05 24.0 0.4 0.0001 22.6 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 FeoB_N PF02421.18 EMC99618.1 - 0.028 13.9 0.6 0.34 10.4 0.3 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 EMC99618.1 - 0.029 14.6 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D3 PF03143.17 EMC99618.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain Med7 PF05983.11 EMC99619.1 - 1.8e-52 178.2 0.6 2.5e-52 177.8 0.6 1.2 1 0 0 1 1 1 1 MED7 protein DUF5327 PF17261.2 EMC99619.1 - 0.028 15.1 4.6 0.041 14.6 0.1 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5327) E1_dh PF00676.20 EMC99620.1 - 1.8e-87 293.1 0.0 2.2e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EMC99620.1 - 0.0028 17.4 0.6 0.032 14.0 0.1 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pex14_N PF04695.13 EMC99620.1 - 0.17 12.6 0.1 0.34 11.5 0.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DXP_synthase_N PF13292.6 EMC99620.1 - 0.17 11.1 0.0 0.5 9.5 0.0 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Methyltr_RsmB-F PF01189.17 EMC99622.1 - 1.2e-23 83.9 0.0 1.4e-22 80.3 0.0 2.4 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EMC99622.1 - 0.0013 18.9 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Gar1 PF04410.14 EMC99623.1 - 5.1e-37 127.0 0.0 6.4e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region 7tm_2 PF00002.24 EMC99624.1 - 4.3e-07 29.5 9.3 1.2e-06 28.0 9.1 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) CRAL_TRIO PF00650.20 EMC99625.1 - 2.2e-46 157.5 0.0 3.3e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMC99625.1 - 3.3e-15 56.0 0.3 8.6e-15 54.7 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EMC99625.1 - 6.9e-07 29.5 0.0 1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain NRBF2 PF08961.10 EMC99625.1 - 0.14 11.8 0.6 0.64 9.6 0.1 2.1 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator G6B PF15096.6 EMC99626.1 - 0.28 10.9 0.1 0.28 10.9 0.1 3.2 2 2 1 3 3 3 0 G6B family PH PF00169.29 EMC99627.1 - 2.2e-05 24.9 0.0 4.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 PH domain eIF-3c_N PF05470.12 EMC99627.1 - 0.018 13.4 0.2 0.026 12.9 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus WEMBL PF05701.11 EMC99627.1 - 0.049 12.3 0.5 0.069 11.8 0.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light ApoO PF09769.9 EMC99627.1 - 0.13 12.2 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein O XPG_N PF00752.17 EMC99628.1 - 5.4e-25 87.8 0.0 1.3e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EMC99628.1 - 6e-21 74.6 0.0 1.2e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EMC99628.1 - 2.8e-06 27.0 0.0 4.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing BORA_N PF15280.6 EMC99628.1 - 0.013 15.1 0.2 0.026 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein aurora borealis N-terminus 5_3_exonuc PF01367.20 EMC99628.1 - 0.014 16.0 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold LPD5 PF18799.1 EMC99628.1 - 0.07 13.5 0.5 0.07 13.5 0.5 1.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 Tma16 PF11176.8 EMC99629.1 - 2.6e-50 170.1 3.9 3.3e-50 169.7 3.9 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DLP_helical PF18709.1 EMC99629.1 - 0.0029 16.9 1.3 0.0035 16.6 1.3 1.2 1 0 0 1 1 1 1 Dynamin-like helical domain Phasin PF05597.11 EMC99629.1 - 0.045 13.8 1.3 0.079 13.0 1.3 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4407 PF14362.6 EMC99629.1 - 4.6 6.5 5.6 14 4.9 5.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 EMC99629.1 - 4.9 7.4 13.0 4.3 7.6 2.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FAD_binding_3 PF01494.19 EMC99630.1 - 3.5e-16 59.4 3.2 2.8e-15 56.4 3.2 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EMC99630.1 - 0.00069 19.8 1.3 0.0028 17.9 1.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMC99630.1 - 0.0013 18.4 5.3 0.0016 18.1 4.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 EMC99630.1 - 0.003 16.6 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.14 EMC99630.1 - 0.0065 15.7 0.4 0.012 14.9 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC99630.1 - 0.0072 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Gp138_N PF18352.1 EMC99630.1 - 0.083 13.0 0.1 8.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Phage protein Gp138 N-terminal domain NAD_binding_9 PF13454.6 EMC99630.1 - 0.22 11.5 1.0 3 7.8 0.9 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FSH1 PF03959.13 EMC99631.1 - 4.9e-30 104.8 0.0 6.4e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EMC99631.1 - 0.0091 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Aminotran_3 PF00202.21 EMC99632.1 - 2e-40 138.7 0.0 1.3e-38 132.7 0.0 2.7 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 EMC99632.1 - 6.9e-23 81.5 0.0 1.1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMC99632.1 - 0.14 12.6 0.1 0.47 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Aminotran_1_2 PF00155.21 EMC99633.1 - 1.1e-38 133.4 0.0 1.3e-38 133.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMC99633.1 - 0.0015 17.1 0.0 0.0022 16.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 EMC99633.1 - 0.0034 16.1 0.0 0.0045 15.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PALP PF00291.25 EMC99633.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Complex1_LYR PF05347.15 EMC99634.1 - 1.6e-08 34.5 0.4 2.1e-08 34.1 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 EMC99635.1 - 8.3e-80 267.6 0.3 1.1e-79 267.1 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMC99635.1 - 9.8e-18 63.8 0.8 2e-17 62.8 0.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EMC99635.1 - 0.0011 18.8 0.1 0.071 13.0 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EMC99635.1 - 0.016 15.9 0.1 1.4 9.6 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 EMC99635.1 - 0.028 14.3 0.2 0.059 13.3 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 EMC99635.1 - 0.029 14.3 0.2 0.14 12.2 0.0 2.2 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain PHD_like PF12910.7 EMC99635.1 - 0.061 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Nucleo_P87 PF07267.11 EMC99635.1 - 0.34 9.7 8.0 0.46 9.3 8.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SOG2 PF10428.9 EMC99635.1 - 0.43 9.7 7.9 0.56 9.3 7.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Histone_H2A_C PF16211.5 EMC99636.1 - 3.5e-21 74.6 2.3 6.2e-21 73.8 2.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EMC99636.1 - 7.6e-17 61.9 0.0 9.9e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EMC99636.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EMC99637.1 - 4e-21 75.7 0.4 4.9e-21 75.5 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EMC99637.1 - 5.3e-05 23.4 0.5 0.00011 22.4 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EMC99637.1 - 0.00028 21.3 0.0 0.00046 20.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 EMC99637.1 - 0.027 15.5 0.3 0.035 15.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 EMC99637.1 - 0.05 13.3 0.1 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.19 EMC99638.1 - 1.1e-95 320.3 0.0 1.3e-95 319.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 PBAN PF05874.11 EMC99638.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Pheromone biosynthesis activating neuropeptide (PBAN) R3H PF01424.22 EMC99639.1 - 2.3e-14 53.1 0.0 4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EMC99639.1 - 2.7e-13 49.6 1.7 7.9e-13 48.1 1.7 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EMC99639.1 - 6.9e-08 32.5 1.1 6.9e-08 32.5 1.1 1.8 2 0 0 2 2 2 1 G-patch domain VHS PF00790.19 EMC99640.1 - 7.1e-46 155.6 0.2 3.3e-45 153.4 0.0 2.2 3 0 0 3 3 3 1 VHS domain Alpha_adaptinC2 PF02883.20 EMC99640.1 - 1.1e-23 83.6 0.6 3e-23 82.2 0.6 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 EMC99640.1 - 1.2e-21 76.8 3.7 2e-21 76.1 0.2 2.9 4 0 0 4 4 4 1 GAT domain GGA_N-GAT PF18308.1 EMC99640.1 - 5.7e-07 29.1 0.1 2.2e-05 24.0 0.0 3.0 3 0 0 3 3 3 1 GGA N-GAT domain Coatamer_beta_C PF07718.12 EMC99640.1 - 0.0039 17.1 0.1 0.0039 17.1 0.1 1.9 2 0 0 2 2 2 1 Coatomer beta C-terminal region Ribo_biogen_C PF04034.13 EMC99641.1 - 4.8e-51 171.8 0.0 6.8e-51 171.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EMC99641.1 - 1.3e-09 37.7 0.1 2.1e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Ribosomal_L33 PF00471.20 EMC99645.1 - 5.4e-06 26.7 0.1 6.4e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Spc7 PF08317.11 EMC99646.1 - 0.0005 19.1 4.1 0.0005 19.1 4.1 6.1 3 2 4 7 7 7 5 Spc7 kinetochore protein RPW8 PF05659.11 EMC99646.1 - 1.5 8.5 12.4 5.6 6.6 0.6 4.3 3 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Zn_clus PF00172.18 EMC99648.1 - 1.4e-05 25.1 10.2 2.4e-05 24.4 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Angiomotin_C PF12240.8 EMC99648.1 - 0.029 13.9 0.7 0.051 13.1 0.7 1.3 1 0 0 1 1 1 0 Angiomotin C terminal MRPL52 PF18699.1 EMC99648.1 - 0.13 12.4 0.8 0.27 11.4 0.8 1.5 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Glyco_hydro_16 PF00722.21 EMC99649.1 - 1.9e-06 27.4 0.1 5.2e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Cellulase PF00150.18 EMC99650.1 - 8.3e-13 48.4 0.4 8.3e-13 48.4 0.4 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 EMC99652.1 - 5.6e-14 52.1 0.0 3e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC99652.1 - 0.00049 19.5 0.0 0.0041 16.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase SOG2 PF10428.9 EMC99652.1 - 3.4 6.8 6.6 4.1 6.5 6.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 EMC99652.1 - 4.4 7.2 21.1 5.7 6.8 21.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2433 PF10360.9 EMC99653.1 - 1.6e-48 163.9 0.0 2.6e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EMC99653.1 - 0.0029 18.1 0.0 0.0086 16.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMC99653.1 - 0.032 14.4 0.0 0.098 12.8 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TFIIA PF03153.13 EMC99653.1 - 0.46 10.4 18.5 0.66 9.9 18.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.22 EMC99656.1 - 9.9e-157 522.1 0.1 1.1e-156 522.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMC99656.1 - 5.3e-06 26.0 0.0 1.1e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) zf-C2H2_2 PF12756.7 EMC99657.1 - 6.5e-35 119.5 7.8 2.4e-29 101.6 1.6 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EMC99657.1 - 4.8e-09 36.3 11.5 0.00087 19.5 0.5 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMC99657.1 - 1.8e-08 34.5 6.2 2e-06 28.0 0.7 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SnoaL_2 PF12680.7 EMC99657.1 - 0.0041 17.7 0.2 0.011 16.3 0.2 1.7 1 0 0 1 1 1 1 SnoaL-like domain zf-C2H2_4 PF13894.6 EMC99657.1 - 0.015 16.1 15.8 4.7 8.3 0.2 5.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMC99657.1 - 0.078 13.5 0.6 0.078 13.5 0.6 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF3835 PF12927.7 EMC99658.1 - 2.9e-20 72.9 2.0 3.8e-19 69.3 0.2 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.6 EMC99658.1 - 1.6e-18 66.6 0.9 3e-17 62.5 0.1 2.6 2 0 0 2 2 2 1 Prefoldin subunit Mod_r PF07200.13 EMC99658.1 - 0.27 11.3 3.9 0.58 10.2 0.9 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MAT1 PF06391.13 EMC99659.1 - 1.9e-39 135.6 18.1 2.5e-39 135.2 18.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EMC99659.1 - 7.5e-30 102.6 8.7 1.3e-29 101.8 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMC99659.1 - 7.6e-05 22.5 6.1 0.00016 21.4 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC99659.1 - 0.0001 22.1 6.0 0.00022 21.0 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC99659.1 - 0.00091 19.5 7.4 0.0016 18.7 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 EMC99659.1 - 0.0019 18.0 4.9 0.021 14.6 2.2 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF86 PF01934.17 EMC99659.1 - 0.0066 16.3 0.1 0.029 14.2 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF86 Zn_ribbon_17 PF17120.5 EMC99659.1 - 0.011 15.3 2.7 0.019 14.6 2.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EMC99659.1 - 0.032 14.2 10.4 0.28 11.2 10.8 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EMC99659.1 - 0.079 12.8 7.0 0.54 10.2 3.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PDEase_I PF00233.19 EMC99659.1 - 0.08 12.6 2.0 0.12 12.1 2.0 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase zf-RING_UBOX PF13445.6 EMC99659.1 - 0.082 13.0 7.8 0.15 12.1 7.8 1.4 1 0 0 1 1 1 0 RING-type zinc-finger MCU PF04678.13 EMC99659.1 - 0.19 11.8 2.4 0.3 11.2 2.4 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Tim17 PF02466.19 EMC99660.1 - 9.4e-33 112.9 7.3 1.2e-32 112.6 7.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 EMC99660.1 - 0.057 13.5 4.3 0.19 11.8 0.3 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III HATPase_c_4 PF13749.6 EMC99660.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.5 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal Pkinase PF00069.25 EMC99661.1 - 1.4e-41 142.6 0.0 5.1e-41 140.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC99661.1 - 2.6e-31 108.8 0.0 4e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC99661.1 - 5.8e-06 25.8 0.0 1.3e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EMC99661.1 - 0.0025 17.8 0.2 1.3 8.9 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EMC99661.1 - 0.036 13.4 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUP PF06516.11 EMC99662.1 - 1.8e-125 418.3 0.6 2e-125 418.1 0.6 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) PLA2_B PF01735.18 EMC99663.1 - 1.8e-178 594.0 6.7 3.8e-178 592.9 6.7 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain adh_short PF00106.25 EMC99664.1 - 3.5e-34 118.0 0.0 4.6e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99664.1 - 1.1e-27 97.1 0.0 1.5e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EMC99664.1 - 0.00036 20.1 0.1 0.0013 18.3 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EMC99664.1 - 0.0098 15.8 0.6 0.2 11.5 0.2 2.3 2 1 0 2 2 2 1 KR domain UPF0146 PF03686.13 EMC99664.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) SAGA-Tad1 PF12767.7 EMC99665.1 - 0.048 13.4 1.0 0.054 13.2 1.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Flavokinase PF01687.17 EMC99666.1 - 1.4e-33 115.5 0.0 1.9e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.25 EMC99667.1 - 0.0023 17.9 0.0 0.025 14.6 0.0 2.4 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 EMC99667.1 - 0.023 14.8 8.6 0.023 14.8 8.6 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM252 PF15664.5 EMC99667.1 - 0.29 10.8 2.1 0.57 9.9 2.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family MFS_1 PF07690.16 EMC99669.1 - 1.4e-39 136.0 29.4 1.4e-39 136.0 29.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMC99669.1 - 0.00031 19.3 2.7 0.00053 18.5 2.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.12 EMC99669.1 - 0.017 13.7 0.7 0.029 13.0 0.0 1.6 2 0 0 2 2 2 0 Ferroportin1 (FPN1) DUF2721 PF11026.8 EMC99669.1 - 0.9 9.4 0.0 0.9 9.4 0.0 4.3 5 1 1 6 6 6 0 Protein of unknown function (DUF2721) Flavoprotein PF02441.19 EMC99670.1 - 4e-20 72.2 0.0 6.6e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 EMC99670.1 - 0.041 14.5 0.0 3.3 8.4 0.0 3.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) DUF4891 PF16232.5 EMC99670.1 - 0.088 13.3 0.0 28 5.3 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4891) TetR_C_8 PF14278.6 EMC99670.1 - 0.14 12.3 0.6 5.5 7.1 0.0 3.6 3 1 0 4 4 4 0 Transcriptional regulator C-terminal region PHY PF00360.20 EMC99671.1 - 1.8e-29 102.4 0.0 3.7e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EMC99671.1 - 2.6e-18 66.5 0.1 5.7e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMC99671.1 - 3.2e-15 56.3 0.0 3.5e-14 52.9 0.0 2.5 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 EMC99671.1 - 3e-14 53.8 0.0 2.8e-12 47.4 0.0 2.8 3 0 0 3 3 3 1 GAF domain HisKA PF00512.25 EMC99671.1 - 1.8e-12 47.1 0.7 5.6e-12 45.5 0.7 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EMC99671.1 - 1.1e-07 32.5 0.0 3.6e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 EMC99671.1 - 0.0072 16.3 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PH_8 PF15409.6 EMC99671.1 - 0.16 12.2 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain UCH_1 PF13423.6 EMC99672.1 - 3.1e-85 286.6 0.2 5.2e-85 285.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EMC99672.1 - 5.6e-14 53.0 0.0 1.8e-13 51.4 0.0 1.9 1 0 0 1 1 1 1 Exonuclease AAA_6 PF12774.7 EMC99672.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PEPCK_ATP PF01293.20 EMC99673.1 - 1.7e-216 719.4 0.0 2e-216 719.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EMC99673.1 - 0.031 14.5 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EMC99673.1 - 0.042 14.2 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EMC99673.1 - 0.097 12.2 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.18 EMC99675.1 - 2.8e-10 40.1 8.1 4.1e-10 39.6 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim54 PF11711.8 EMC99676.1 - 0.00032 19.6 1.3 0.00044 19.1 1.3 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Phasin PF05597.11 EMC99676.1 - 0.56 10.2 0.0 0.56 10.2 0.0 3.1 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SNF2_N PF00176.23 EMC99677.1 - 4e-67 226.4 0.0 5.5e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EMC99677.1 - 2.5e-18 65.8 0.0 5.6e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EMC99677.1 - 9.2e-14 51.7 0.0 2.2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EMC99677.1 - 2.4e-09 36.9 8.6 4.9e-09 35.9 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC99677.1 - 6.1e-09 36.1 8.1 6.1e-09 36.1 8.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EMC99677.1 - 6e-08 32.6 6.6 1.2e-07 31.6 6.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EMC99677.1 - 4.4e-07 29.7 9.1 9.1e-07 28.7 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMC99677.1 - 8.9e-07 28.7 5.7 8.9e-07 28.7 5.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMC99677.1 - 9.5e-07 29.0 5.9 2.5e-06 27.7 5.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EMC99677.1 - 1.7e-06 28.1 7.7 3.2e-06 27.2 7.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 EMC99677.1 - 1.9e-06 28.0 0.0 4.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 EMC99677.1 - 4.2e-06 26.6 6.6 8.4e-06 25.6 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 EMC99677.1 - 3e-05 23.7 7.0 7.7e-05 22.4 7.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EMC99677.1 - 4e-05 23.4 6.4 9.5e-05 22.2 6.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EMC99677.1 - 0.0064 16.5 2.0 0.017 15.2 2.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 EMC99677.1 - 0.01 16.0 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.6 EMC99677.1 - 0.014 15.2 2.5 0.034 14.0 2.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.14 EMC99677.1 - 0.017 14.9 2.7 3.7 7.5 0.3 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 EMC99677.1 - 0.037 13.8 3.4 0.12 12.1 3.4 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 EMC99677.1 - 0.31 11.2 5.2 0.74 10.0 5.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EMC99677.1 - 0.66 9.8 5.0 2.6 7.9 5.2 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Transket_pyr PF02779.24 EMC99681.1 - 4.2e-45 153.6 0.1 6.2e-45 153.0 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EMC99681.1 - 7.6e-32 109.8 0.0 5.7e-31 107.0 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain PH PF00169.29 EMC99683.1 - 0.00029 21.3 0.0 0.00054 20.4 0.0 1.5 1 0 0 1 1 1 1 PH domain BORCS7 PF16088.5 EMC99683.1 - 0.059 13.6 2.7 0.064 13.5 0.6 2.0 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 FHIPEP PF00771.20 EMC99683.1 - 0.1 11.0 0.2 0.13 10.7 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family Zds_C PF08632.10 EMC99684.1 - 1.7e-28 98.1 1.5 3.2e-28 97.2 1.5 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Sin_N PF04801.13 EMC99684.1 - 3.8 6.6 16.1 0.091 12.0 8.9 1.8 2 0 0 2 2 2 0 Sin-like protein conserved region EF_assoc_2 PF08356.12 EMC99685.1 - 6.6e-32 109.4 0.0 1.5e-31 108.2 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EMC99685.1 - 6.6e-30 102.5 0.3 1.5e-29 101.4 0.3 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EMC99685.1 - 5.7e-25 87.8 0.0 1.4e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EMC99685.1 - 1.4e-13 51.1 0.0 1.6e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EMC99685.1 - 1e-09 38.4 0.0 0.00018 21.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 EMC99685.1 - 5.1e-06 25.7 1.1 0.1 12.2 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EMC99685.1 - 1.3e-05 25.6 0.1 0.017 15.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EMC99685.1 - 2e-05 24.1 3.9 0.059 13.3 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain Dynamin_N PF00350.23 EMC99685.1 - 3.1e-05 24.1 0.0 0.1 12.6 0.0 2.8 3 0 0 3 3 3 2 Dynamin family EF-hand_5 PF13202.6 EMC99685.1 - 0.0051 16.2 3.3 1.2 8.8 0.4 2.7 2 0 0 2 2 2 2 EF hand AAA_28 PF13521.6 EMC99685.1 - 0.0052 17.0 0.0 4.4 7.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EMC99685.1 - 0.0087 16.5 0.0 1.8 9.0 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 EMC99685.1 - 0.01 16.2 0.0 6.6 7.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 EMC99685.1 - 0.014 15.6 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EMC99685.1 - 0.021 14.7 0.1 6.8 6.6 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 EMC99685.1 - 0.049 13.2 0.0 11 5.5 0.0 2.6 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain EF-hand_8 PF13833.6 EMC99685.1 - 0.068 13.0 1.2 8 6.4 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair FeoB_N PF02421.18 EMC99685.1 - 0.071 12.6 0.1 6.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B EF-hand_10 PF14788.6 EMC99685.1 - 0.15 12.0 0.3 0.74 9.7 0.1 2.0 2 0 0 2 2 2 0 EF hand ATPase_2 PF01637.18 EMC99685.1 - 0.24 11.3 0.0 6 6.7 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea WD40 PF00400.32 EMC99686.1 - 1.4e-12 47.8 8.9 0.0012 19.6 0.2 5.8 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC99686.1 - 6.2e-08 32.8 0.0 5.2e-06 26.7 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMC99686.1 - 0.00091 19.2 0.1 0.04 13.8 0.0 2.3 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EMC99686.1 - 0.0012 17.8 0.0 0.0041 16.1 0.0 1.8 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EMC99686.1 - 0.0052 16.7 0.0 5.4 7.1 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EMC99686.1 - 0.011 14.2 0.1 0.041 12.4 0.1 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 EMC99686.1 - 0.033 13.9 0.0 5.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Coatomer_WDAD PF04053.14 EMC99686.1 - 0.033 13.2 0.0 0.15 11.0 0.0 1.9 1 1 1 2 2 2 0 Coatomer WD associated region YpsA PF06908.11 EMC99686.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family Arrestin_C PF02752.22 EMC99687.1 - 7e-13 49.2 0.1 1.6e-12 48.0 0.1 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EMC99687.1 - 1.4e-07 31.6 0.1 1.5e-05 25.1 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EMC99687.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like zf-Di19 PF05605.12 EMC99688.1 - 0.036 14.4 0.1 0.066 13.5 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 EMC99688.1 - 0.057 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 EMC99688.1 - 0.066 14.1 0.4 0.18 12.7 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Gpr1_Fun34_YaaH PF01184.19 EMC99689.1 - 7.5e-79 264.1 18.6 8.6e-79 263.9 18.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DIOX_N PF14226.6 EMC99690.1 - 2.7e-12 47.5 0.0 4.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMC99690.1 - 3.3e-09 37.1 0.0 6.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ODAM PF15424.6 EMC99690.1 - 0.0031 17.1 0.0 0.096 12.3 0.0 2.6 3 0 0 3 3 3 1 Odontogenic ameloblast-associated family Peptidase_M24 PF00557.24 EMC99691.1 - 9.2e-50 169.2 0.0 1.2e-48 165.6 0.0 2.3 2 1 1 3 3 3 1 Metallopeptidase family M24 AMP_N PF05195.16 EMC99691.1 - 3.4e-39 133.4 0.0 5.9e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SIR2 PF02146.17 EMC99692.1 - 8.1e-38 130.1 0.0 2.2e-37 128.7 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Pkinase PF00069.25 EMC99693.1 - 4.9e-62 209.7 0.0 6.5e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC99693.1 - 5.1e-31 107.9 0.0 6.8e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC99693.1 - 0.00043 19.7 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMC99693.1 - 0.0015 18.5 0.4 0.0086 16.0 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EMC99693.1 - 0.0016 17.8 0.3 0.0032 16.8 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMC99693.1 - 0.0041 16.0 0.1 0.013 14.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EMC99693.1 - 0.11 11.4 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain UQ_con PF00179.26 EMC99694.1 - 5.4e-37 126.6 0.1 6.6e-37 126.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UCH PF00443.29 EMC99695.1 - 4.8e-53 180.3 0.0 6.6e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC99695.1 - 2.8e-19 69.9 0.1 1e-18 68.0 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EMC99695.1 - 0.0022 18.5 0.0 0.0054 17.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.19 EMC99696.1 - 1.8e-39 134.8 1.3 1.4e-38 131.9 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EMC99696.1 - 1e-15 57.6 0.9 2.1e-15 56.6 0.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAT PF03127.14 EMC99696.1 - 4.1e-05 23.8 0.2 0.00014 22.1 0.0 2.1 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EMC99696.1 - 8.2e-05 22.3 18.2 0.0056 16.5 3.5 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 EMC99696.1 - 0.067 13.4 0.5 0.17 12.1 0.5 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 EMC99696.1 - 0.084 12.8 1.6 0.16 11.9 1.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_20 PF14561.6 EMC99696.1 - 0.39 11.1 4.3 3.9 7.9 2.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat OrfB_Zn_ribbon PF07282.11 EMC99696.1 - 1.1 9.2 3.4 3.1 7.8 3.4 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Glyco_hydro_64 PF16483.5 EMC99698.1 - 8.7e-133 443.1 2.7 9.9e-133 443.0 2.7 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF572 PF04502.13 EMC99699.1 - 1.4e-61 208.9 0.6 1.9e-61 208.6 0.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Pkinase PF00069.25 EMC99700.1 - 3.4e-68 229.9 0.0 4.9e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC99700.1 - 2.3e-29 102.5 0.0 2.9e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMC99700.1 - 0.012 14.6 0.0 0.23 10.3 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EMC99700.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EMC99700.1 - 0.041 13.2 0.1 0.14 11.4 0.0 1.8 2 1 0 2 2 2 0 Kinase-like Rad4 PF03835.15 EMC99701.1 - 3.1e-33 114.5 0.0 7e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EMC99701.1 - 8.1e-28 96.7 0.2 1.5e-27 95.8 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EMC99701.1 - 3e-20 71.8 0.2 6.5e-20 70.7 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EMC99701.1 - 9e-19 68.2 0.5 9e-19 68.2 0.5 3.4 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EMC99701.1 - 0.0013 19.1 0.0 0.0077 16.7 0.0 2.4 2 1 0 2 2 2 1 Transglutaminase-like superfamily NTP_transferase PF00483.23 EMC99702.1 - 1.5e-32 113.2 0.0 2e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EMC99702.1 - 4.4e-10 38.9 6.5 1.6e-06 27.6 0.2 3.4 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EMC99702.1 - 6.1e-08 33.2 0.0 1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2968 PF11180.8 EMC99702.1 - 0.045 13.4 0.1 0.069 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) IspD PF01128.19 EMC99702.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase MDM10 PF12519.8 EMC99703.1 - 0.054 12.3 0.1 0.054 12.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Dynamin_N PF00350.23 EMC99704.1 - 1.1e-18 67.9 0.0 2.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EMC99704.1 - 4.3e-13 49.1 0.0 1e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 EMC99704.1 - 0.00029 20.9 0.0 0.00079 19.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_23 PF13476.6 EMC99704.1 - 0.0038 17.8 0.9 0.12 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EMC99704.1 - 0.011 16.0 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EMC99704.1 - 0.016 14.6 0.0 0.048 13.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 EMC99704.1 - 0.024 14.7 0.0 0.69 10.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EMC99704.1 - 0.071 13.6 0.0 0.55 10.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EMC99704.1 - 0.15 12.4 5.9 1.2 9.5 0.0 3.7 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 EMC99704.1 - 0.18 11.5 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Putative_PNPOx PF01243.20 EMC99705.1 - 2.4e-08 34.0 0.0 0.0018 18.5 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase KCH PF16944.5 EMC99708.1 - 1.3e-101 339.6 11.0 1.5e-101 339.4 11.0 1.0 1 0 0 1 1 1 1 Fungal potassium channel Connexin PF00029.19 EMC99708.1 - 0.071 12.9 2.3 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Connexin Tannase PF07519.11 EMC99709.1 - 1.1e-93 314.7 7.9 1.7e-93 314.1 7.9 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Ysc84 PF04366.12 EMC99710.1 - 8.4e-40 135.5 0.3 1.2e-39 134.9 0.3 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EMC99710.1 - 6e-14 51.4 0.2 2.4e-13 49.4 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EMC99710.1 - 4.9e-13 48.5 0.0 1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EMC99710.1 - 3.1e-09 36.5 0.0 5.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2561 PF10812.8 EMC99711.1 - 0.018 15.1 0.3 0.019 15.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Synaptobrevin PF00957.21 EMC99711.1 - 0.042 13.6 0.8 0.095 12.5 0.6 1.7 1 1 1 2 2 2 0 Synaptobrevin DUF4349 PF14257.6 EMC99711.1 - 0.059 12.8 0.1 0.068 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) ArfGap PF01412.18 EMC99712.1 - 1.9e-41 140.8 0.9 3.4e-41 140.0 0.9 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf tRNA-synt_2 PF00152.20 EMC99714.1 - 5.8e-70 235.8 0.2 9.4e-70 235.2 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) TFIIS_M PF07500.14 EMC99714.1 - 4.5e-18 65.8 2.2 4.5e-18 65.8 2.2 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EMC99714.1 - 5.3e-15 55.6 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 EMC99714.1 - 3.9e-08 33.1 7.0 8.2e-08 32.0 7.0 1.6 1 0 0 1 1 1 1 PHD-finger tRNA_anti-codon PF01336.25 EMC99714.1 - 1.1e-06 28.5 0.0 3.3e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMC99714.1 - 2.3e-05 24.0 0.2 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Hypoth_Ymh PF09509.10 EMC99714.1 - 3 7.8 5.3 1.4 8.8 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) Prominin PF05478.11 EMC99715.1 - 2.1e-06 26.1 4.1 2.9e-06 25.6 3.0 1.6 1 1 1 2 2 2 1 Prominin Gp-FAR-1 PF05823.12 EMC99715.1 - 0.00033 21.0 2.4 0.00052 20.4 1.1 1.9 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) LMBR1 PF04791.16 EMC99715.1 - 0.0021 17.1 0.8 0.0029 16.6 0.8 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein CALCOCO1 PF07888.11 EMC99715.1 - 0.0029 16.5 8.6 0.006 15.5 8.6 1.5 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like PI3K_P85_iSH2 PF16454.5 EMC99715.1 - 0.0075 15.9 6.6 1 8.9 4.1 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain VWA_2 PF13519.6 EMC99715.1 - 0.011 16.4 5.8 0.069 13.8 0.5 2.9 2 1 1 3 3 2 0 von Willebrand factor type A domain AAA_13 PF13166.6 EMC99715.1 - 0.034 12.8 7.2 0.18 10.4 8.6 1.4 2 0 0 2 2 2 0 AAA domain Prefoldin PF02996.17 EMC99715.1 - 0.037 13.9 3.9 4.3 7.3 0.1 3.3 3 1 0 3 3 3 0 Prefoldin subunit PspA_IM30 PF04012.12 EMC99715.1 - 0.15 11.6 8.0 1.7 8.2 0.1 2.4 1 1 0 2 2 2 0 PspA/IM30 family TACC_C PF05010.14 EMC99715.1 - 0.24 11.2 10.8 0.44 10.3 7.0 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT57 PF10498.9 EMC99715.1 - 0.31 10.0 11.8 0.65 8.9 11.2 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DLP_helical PF18709.1 EMC99715.1 - 0.32 10.1 11.9 0.27 10.4 1.9 3.0 1 1 2 3 3 3 0 Dynamin-like helical domain BLOC1_2 PF10046.9 EMC99715.1 - 0.35 11.2 9.4 0.17 12.2 0.5 3.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 EMC99715.1 - 0.52 10.3 9.6 1.5 8.9 3.5 2.5 1 1 1 2 2 2 0 Laminin Domain II PRKG1_interact PF15898.5 EMC99715.1 - 0.9 10.5 5.6 6.7 7.7 3.7 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Phage_GPO PF05929.11 EMC99715.1 - 0.93 9.1 11.9 5.8 6.4 7.6 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.15 EMC99715.1 - 2.1 7.8 9.6 0.88 9.1 7.3 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EMC99715.1 - 2.2 8.4 9.8 1.8 8.6 1.4 2.8 2 1 0 3 3 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 EMC99715.1 - 2.5 8.8 6.3 56 4.4 0.0 2.8 2 0 0 2 2 2 0 Initiation control protein YabA Sigma70_ner PF04546.13 EMC99715.1 - 2.8 7.8 10.9 0.56 10.1 0.5 2.3 1 1 1 2 2 2 0 Sigma-70, non-essential region RecG_N PF17190.4 EMC99715.1 - 3 8.6 5.4 14 6.5 1.8 3.0 1 1 2 3 3 3 0 RecG N-terminal helical domain OmpH PF03938.14 EMC99715.1 - 3.9 7.8 9.1 4.1 7.7 7.7 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 EMC99715.1 - 4.3 7.8 6.0 38 4.8 0.2 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 EMC99715.1 - 5.7 7.7 8.0 14 6.5 0.7 3.2 1 1 1 3 3 3 0 Occludin homology domain Com_YlbF PF06133.11 EMC99715.1 - 7.4 7.2 10.6 13 6.4 5.3 3.0 1 1 2 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA Ribosomal_L6 PF00347.23 EMC99716.1 - 7e-23 81.1 0.0 1.1e-11 45.2 0.0 2.9 2 1 0 2 2 2 2 Ribosomal protein L6 COX5B PF01215.19 EMC99717.1 - 5.4e-57 191.0 0.0 7.6e-57 190.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb NUDIX PF00293.28 EMC99718.1 - 1.6e-07 31.4 0.0 3.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain ADH_N PF08240.12 EMC99719.1 - 4.8e-05 23.2 0.0 0.00018 21.3 0.0 1.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMC99719.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Kinesin PF00225.23 EMC99720.1 - 5.1e-113 377.4 0.0 6.9e-113 376.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMC99720.1 - 5.3e-27 94.6 0.0 1.2e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 EMC99720.1 - 0.014 15.5 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain TRF PF08558.10 EMC99720.1 - 0.055 13.1 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) Bul1_C PF04426.12 EMC99720.1 - 0.1 12.0 0.6 0.21 11.0 0.6 1.5 1 0 0 1 1 1 0 Bul1 C terminus Fungal_lectin_2 PF18647.1 EMC99722.1 - 0.067 13.6 0.0 0.092 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin ABC_membrane PF00664.23 EMC99723.1 - 3.2e-34 118.8 10.3 8.2e-34 117.5 10.3 1.8 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMC99723.1 - 1.8e-32 112.7 0.0 4.4e-32 111.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMC99723.1 - 2.5e-07 30.4 0.3 7.1e-06 25.6 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EMC99723.1 - 0.0032 17.7 0.2 0.026 14.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EMC99723.1 - 0.018 15.3 1.5 0.29 11.4 0.4 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EMC99723.1 - 0.021 14.7 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 EMC99723.1 - 0.026 14.5 0.2 0.34 10.9 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMC99723.1 - 0.041 14.3 0.1 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EMC99723.1 - 0.049 13.4 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pex24p PF06398.11 EMC99723.1 - 1.5 7.7 4.2 2.1 7.2 2.8 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Alk_phosphatase PF00245.20 EMC99724.1 - 9.1e-108 360.9 0.2 1.3e-107 360.3 0.2 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EMC99724.1 - 8.2e-07 28.6 0.1 1.7e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Gpr1_Fun34_YaaH PF01184.19 EMC99725.1 - 3.2e-28 98.8 24.2 4e-28 98.5 24.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2070 PF09843.9 EMC99725.1 - 5.3 5.2 7.1 6.2 5.0 7.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2614 PF11023.8 EMC99725.1 - 8.7 6.5 7.6 13 5.9 6.9 1.6 1 1 0 1 1 1 0 Zinc-ribbon containing domain DUF3630 PF12305.8 EMC99726.1 - 0.043 13.9 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) zf-C3HC PF07967.13 EMC99727.1 - 1.4e-37 128.7 0.1 5e-27 94.5 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EMC99727.1 - 3.2e-21 75.3 0.2 2.3e-20 72.5 0.2 2.4 2 1 0 2 2 2 1 Rsm1-like AA_permease_2 PF13520.6 EMC99728.1 - 2e-43 148.8 44.2 2.5e-43 148.5 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMC99728.1 - 4.4e-19 68.4 39.0 5.8e-19 68.0 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease SID-1_RNA_chan PF13965.6 EMC99728.1 - 0.12 10.8 4.6 0.26 9.7 4.6 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PhyH PF05721.13 EMC99729.1 - 0.0029 17.9 0.0 0.0033 17.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 EMC99730.1 - 1.8e-09 37.0 0.0 2.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC99730.1 - 1.8e-08 34.4 10.4 4e-08 33.3 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_MT_bd PF06657.13 EMC99731.1 - 7.7e-27 93.6 1.0 7.7e-27 93.6 1.0 4.5 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EMC99731.1 - 1.9e-12 47.1 0.2 1.9e-12 47.1 0.2 4.2 3 1 1 4 4 4 2 Centrosome localisation domain of PPC89 ZapB PF06005.12 EMC99731.1 - 0.0038 17.6 1.4 0.0038 17.6 1.4 4.3 4 0 0 4 4 4 2 Cell division protein ZapB CCDC92 PF14916.6 EMC99731.1 - 0.041 13.7 0.2 0.79 9.5 0.0 2.8 3 0 0 3 3 3 0 Coiled-coil domain of unknown function MCC-bdg_PDZ PF10506.9 EMC99731.1 - 0.057 13.4 1.1 1.1 9.4 0.3 3.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Diphthamide_syn PF01866.17 EMC99732.1 - 7.8e-86 288.2 0.0 1.1e-85 287.8 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DDE_3 PF13358.6 EMC99733.1 - 0.00045 20.0 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Ca_chan_IQ PF08763.11 EMC99733.1 - 0.32 11.3 2.8 22 5.4 0.0 2.5 2 1 0 2 2 2 0 Voltage gated calcium channel IQ domain RCC1 PF00415.18 EMC99734.1 - 3e-23 82.2 0.6 2.5e-05 24.8 0.0 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EMC99734.1 - 1e-14 54.7 0.0 6.4e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 EMC99734.1 - 1.6e-08 34.9 0.6 6e-07 29.9 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.6 EMC99734.1 - 1.7e-08 34.0 4.0 5.7e-07 29.2 0.4 3.6 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 EMC99734.1 - 1.8e-06 28.5 0.1 4.3e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMC99734.1 - 0.00048 20.4 0.3 0.59 10.5 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMC99734.1 - 0.002 18.4 0.4 1.3 9.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EMC99734.1 - 0.084 13.4 0.4 4.4 7.9 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat GMC_oxred_N PF00732.19 EMC99736.1 - 3.6e-55 187.4 0.0 5.2e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EMC99736.1 - 5.9e-33 114.4 0.0 9.9e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EMC99736.1 - 9.8e-07 28.2 0.0 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EMC99736.1 - 0.011 14.5 0.0 0.98 8.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 EMC99736.1 - 0.013 15.1 1.4 1.8 8.1 0.3 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMC99736.1 - 0.034 13.4 0.7 0.067 12.4 0.1 1.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EMC99736.1 - 0.13 12.5 0.4 0.28 11.4 0.4 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 EMC99736.1 - 0.2 10.9 0.1 0.47 9.7 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-RING_4 PF14570.6 EMC99740.1 - 1.9e-20 72.4 12.5 3.5e-20 71.5 12.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EMC99740.1 - 3.6e-09 36.3 0.0 1e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 EMC99740.1 - 2.4e-06 27.3 7.0 2.4e-06 27.3 7.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EMC99740.1 - 0.00014 22.1 9.0 0.00032 21.0 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EMC99740.1 - 0.0004 20.2 8.1 0.0069 16.2 3.6 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 Rtf2 PF04641.12 EMC99740.1 - 0.0013 18.1 3.8 0.0013 18.1 3.8 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger Baculo_IE-1 PF05290.11 EMC99740.1 - 0.0031 17.5 5.5 0.0071 16.3 5.5 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 EMC99740.1 - 0.0082 16.3 2.9 0.018 15.1 2.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EMC99740.1 - 0.014 15.6 3.7 0.046 13.9 3.7 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger zf-UDP PF14569.6 EMC99740.1 - 0.025 14.7 7.2 0.026 14.6 5.5 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 EMC99740.1 - 0.028 14.3 9.9 0.067 13.1 9.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYDLN_acid PF09538.10 EMC99740.1 - 0.87 10.3 5.4 1.3 9.8 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Complex1_30kDa PF00329.19 EMC99741.1 - 1.3e-44 151.7 0.0 1.9e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HAMP PF00672.25 EMC99741.1 - 0.084 13.3 2.9 0.73 10.3 0.8 2.6 2 0 0 2 2 2 0 HAMP domain MFS_1 PF07690.16 EMC99742.1 - 1.4e-42 145.9 43.9 1.4e-42 145.9 43.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC99742.1 - 2.7e-15 56.2 8.2 2.7e-15 56.2 8.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter ArAE_1 PF06081.11 EMC99742.1 - 0.029 14.5 0.4 0.029 14.5 0.4 2.4 3 1 0 3 3 3 0 Aromatic acid exporter family member 1 Vps51 PF08700.11 EMC99742.1 - 0.045 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Vps51/Vps67 DUF4191 PF13829.6 EMC99742.1 - 0.13 11.6 0.1 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) OATP PF03137.20 EMC99742.1 - 1.3 7.2 13.9 0.0071 14.7 2.7 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PAP2 PF01569.21 EMC99743.1 - 1.1e-26 93.2 0.8 2.5e-26 92.0 0.8 1.6 1 0 0 1 1 1 1 PAP2 superfamily AGTRAP PF06396.11 EMC99743.1 - 0.13 12.0 0.6 0.69 9.7 0.2 1.9 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF983 PF06170.12 EMC99743.1 - 7.8 7.0 7.0 1.5 9.3 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Fe-ADH PF00465.19 EMC99744.1 - 3.2e-100 335.5 0.1 4.1e-100 335.1 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EMC99744.1 - 1.7e-14 54.1 0.0 1.6e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase 2-Hacid_dh_C PF02826.19 EMC99745.1 - 2.5e-56 189.8 0.0 5.2e-56 188.8 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMC99745.1 - 3.9e-36 123.7 0.3 7.6e-36 122.7 0.3 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EMC99745.1 - 0.0054 16.5 0.3 0.047 13.5 0.0 2.6 2 0 0 2 2 2 1 ACT domain UDPG_MGDP_dh_C PF03720.15 EMC99745.1 - 0.065 13.7 0.0 0.3 11.5 0.0 2.0 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain AdoHcyase_NAD PF00670.21 EMC99745.1 - 0.09 12.8 1.9 0.1 12.6 0.3 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HECT PF00632.25 EMC99746.1 - 2.4e-76 257.2 0.0 5.3e-76 256.0 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EMC99746.1 - 0.00031 20.7 3.3 2 8.6 0.0 5.9 6 1 1 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EMC99746.1 - 0.0054 17.2 0.2 0.35 11.4 0.0 3.8 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 EMC99746.1 - 0.025 14.8 0.3 0.4 11.1 0.1 3.3 3 0 0 3 3 3 0 HEAT repeat Lipase_chap PF03280.14 EMC99746.1 - 0.53 10.2 4.3 0.14 12.1 0.2 2.2 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein TraQ PF09679.10 EMC99747.1 - 0.003 17.4 0.1 0.0068 16.3 0.1 1.5 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin chaperone (TraQ) DUF308 PF03729.13 EMC99747.1 - 0.052 13.9 0.1 0.092 13.1 0.1 1.3 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Paxillin PF03535.13 EMC99747.1 - 0.055 13.4 0.1 0.055 13.4 0.1 2.1 2 0 0 2 2 2 0 Paxillin family SKG6 PF08693.10 EMC99747.1 - 0.087 12.3 3.5 0.22 11.0 3.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TauD PF02668.16 EMC99749.1 - 8.9e-53 179.8 0.8 1e-52 179.6 0.8 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RepA_C PF04796.12 EMC99749.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Plasmid encoded RepA protein Aminotran_1_2 PF00155.21 EMC99750.1 - 3.7e-40 138.2 0.0 5.6e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 EMC99751.1 - 3.1e-24 85.6 30.9 3.1e-24 85.6 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Chromo PF00385.24 EMC99752.1 - 7.7e-14 51.3 1.9 1.2e-13 50.8 0.6 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EMC99752.1 - 6.9e-12 45.3 0.3 3.3e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Cpn60_TCP1 PF00118.24 EMC99753.1 - 1e-155 519.1 5.8 1.2e-155 518.9 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FlhD PF05247.13 EMC99753.1 - 0.028 14.7 0.0 4.9 7.5 0.0 2.9 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhD) zinc_ribbon_15 PF17032.5 EMC99754.1 - 0.00099 19.8 0.5 0.19 12.5 0.1 2.7 2 0 0 2 2 2 1 zinc-ribbon family zf-CCCH PF00642.24 EMC99754.1 - 0.011 15.7 2.7 0.011 15.7 2.7 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HypA PF01155.19 EMC99754.1 - 0.11 12.5 2.3 0.39 10.8 0.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EMC99754.1 - 0.18 11.9 3.9 3.8 7.6 0.3 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-CCCH_4 PF18044.1 EMC99754.1 - 0.22 11.4 3.6 0.57 10.1 3.6 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger Torus PF16131.5 EMC99754.1 - 0.31 11.7 3.9 0.82 10.4 0.3 2.5 2 0 0 2 2 2 0 Torus domain DUF3295 PF11702.8 EMC99755.1 - 1.4e-170 568.9 38.0 1.7e-170 568.7 38.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EMC99755.1 - 1.2e-12 47.4 4.3 1.1e-10 41.2 3.4 2.6 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF1752) ERM PF00769.19 EMC99758.1 - 0.0034 17.3 22.9 0.0034 17.3 22.9 7.0 2 2 4 6 6 6 2 Ezrin/radixin/moesin family L27 PF02828.16 EMC99758.1 - 0.16 11.8 5.7 0.29 10.9 0.2 4.2 4 0 0 4 4 4 0 L27 domain DUF3800 PF12686.7 EMC99758.1 - 2.6 8.7 6.1 7.8e+02 0.7 6.0 3.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) zf-met PF12874.7 EMC99759.1 - 0.00011 22.5 0.9 0.00017 21.9 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type OTT_1508_deam PF14441.6 EMC99759.1 - 0.0022 17.9 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-C2H2_2 PF12756.7 EMC99759.1 - 0.008 16.5 0.0 0.0083 16.4 0.0 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EMC99759.1 - 0.0081 16.4 0.2 0.011 16.0 0.2 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1677 PF07911.13 EMC99759.1 - 0.014 15.7 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) OrsD PF12013.8 EMC99759.1 - 0.046 14.2 0.1 0.057 13.9 0.1 1.2 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Peptidase_C2 PF00648.21 EMC99760.1 - 2.6e-66 223.6 0.3 1.2e-44 152.5 0.2 2.2 1 1 1 2 2 2 2 Calpain family cysteine protease DUF2828 PF11443.8 EMC99760.1 - 0.085 10.9 6.2 0.14 10.2 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Utp14 PF04615.13 EMC99760.1 - 0.52 8.8 29.3 0.023 13.3 22.5 1.8 2 0 0 2 2 2 0 Utp14 protein VHS PF00790.19 EMC99762.1 - 1.2e-20 73.8 0.0 2.9e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EMC99762.1 - 3.3e-05 24.1 1.6 4.1e-05 23.8 0.3 1.9 2 0 0 2 2 2 1 GAT domain KAR9 PF08580.10 EMC99762.1 - 0.11 11.1 2.3 0.19 10.2 2.3 1.4 1 0 0 1 1 1 0 Yeast cortical protein KAR9 F-actin_cap_A PF01267.17 EMC99765.1 - 1.5e-87 293.4 0.1 1.7e-87 293.3 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit HSCB_C PF07743.13 EMC99765.1 - 0.016 15.7 0.0 0.66 10.5 0.0 2.4 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain CCP_MauG PF03150.14 EMC99765.1 - 0.051 14.2 0.0 0.073 13.7 0.0 1.4 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase CdiI_2 PF18593.1 EMC99765.1 - 0.058 14.0 0.0 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 CdiI immunity protein Alph_Pro_TM PF09608.10 EMC99765.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) AAA_12 PF13087.6 EMC99766.1 - 1.2e-40 139.3 0.0 2e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EMC99766.1 - 6.7e-26 91.6 0.0 3.4e-25 89.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EMC99766.1 - 6.8e-07 29.7 0.0 8.5e-06 26.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMC99766.1 - 1.4e-06 28.2 0.1 0.0064 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EMC99766.1 - 0.00081 19.0 0.1 0.0041 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EMC99766.1 - 0.0014 17.9 0.3 0.58 9.3 0.1 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 EMC99766.1 - 0.019 14.8 0.4 0.15 11.9 0.0 2.7 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EMC99766.1 - 0.038 14.3 0.0 0.55 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EMC99766.1 - 0.058 13.8 2.2 0.17 12.2 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain AAA_5 PF07728.14 EMC99766.1 - 0.086 12.8 0.3 0.28 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EMC99766.1 - 0.16 11.9 0.1 0.57 10.1 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain NIF PF03031.18 EMC99767.1 - 1.3e-35 122.4 0.0 1.9e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_hydro_2_C PF02836.17 EMC99767.1 - 0.088 11.9 0.0 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_47 PF01532.20 EMC99768.1 - 2.8e-111 372.6 0.0 3.6e-111 372.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APC_basic PF05956.11 EMC99768.1 - 2.1 7.7 8.1 3.6 7.0 8.1 1.2 1 0 0 1 1 1 0 APC basic domain Ribosomal_60s PF00428.19 EMC99768.1 - 2.7 8.7 5.1 6.4 7.4 5.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein CPDase PF07823.11 EMC99769.1 - 2.1e-27 96.1 0.0 2.4e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EMC99769.1 - 0.00027 20.9 0.3 0.024 14.6 0.1 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily Phage_T4_gp19 PF06841.12 EMC99769.1 - 0.087 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 TRP PF06011.12 EMC99770.1 - 7.2e-35 120.5 26.6 3e-33 115.2 26.6 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EMC99770.1 - 3.7e-21 75.9 0.1 6e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 ML-like domain BNR_6 PF15899.5 EMC99771.1 - 0.0017 18.2 0.3 1 9.6 0.1 2.8 2 0 0 2 2 2 2 BNR-Asp box repeat Sortilin-Vps10 PF15902.5 EMC99771.1 - 0.024 13.5 0.4 4.7 5.9 0.0 2.3 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 EMC99771.1 - 0.032 14.2 8.6 0.8 10.0 1.2 3.8 3 0 0 3 3 3 0 BNR/Asp-box repeat MFS_1 PF07690.16 EMC99772.1 - 1.8e-34 119.2 42.6 1.8e-34 119.2 42.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 EMC99772.1 - 4.9e-05 22.3 0.7 4.9e-05 22.3 0.7 2.9 2 1 1 3 3 3 1 LacY proton/sugar symporter LrgA PF03788.14 EMC99772.1 - 0.5 10.4 7.9 0.086 12.8 1.2 2.9 1 1 1 2 2 2 0 LrgA family His_Phos_2 PF00328.22 EMC99773.1 - 3e-35 122.3 0.0 3.6e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HEAT PF02985.22 EMC99774.1 - 1.2e-18 65.5 7.5 0.00014 21.9 0.3 9.8 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 EMC99774.1 - 1.6e-17 63.6 15.0 6.1e-06 26.6 0.5 9.8 9 2 2 11 11 11 4 HEAT-like repeat HEAT_2 PF13646.6 EMC99774.1 - 5.9e-16 58.6 9.7 0.0088 16.4 0.3 8.5 6 3 1 7 7 7 4 HEAT repeats IBN_N PF03810.19 EMC99774.1 - 2.1e-13 50.0 1.8 6.1e-12 45.3 0.3 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 EMC99774.1 - 1.1e-12 48.1 0.0 0.055 13.2 0.0 5.5 4 2 1 5 5 5 4 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EMC99774.1 - 4e-09 36.9 2.5 0.45 11.1 0.0 5.8 6 0 0 6 6 6 3 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EMC99774.1 - 6.8e-08 32.0 10.6 0.0016 17.6 0.7 4.8 3 1 1 4 4 4 3 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 EMC99774.1 - 3.6e-07 29.1 1.9 0.00064 18.4 0.0 3.7 3 1 0 3 3 3 1 Adaptin N terminal region Arm PF00514.23 EMC99774.1 - 8.4e-07 28.8 0.5 9.5 6.4 0.0 6.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat UME PF08064.13 EMC99774.1 - 9.6e-07 28.7 0.4 0.013 15.4 0.1 4.7 4 1 0 4 4 4 1 UME (NUC010) domain Cnd1 PF12717.7 EMC99774.1 - 4e-06 27.0 7.5 4 7.5 0.0 5.7 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EMC99774.1 - 0.00053 19.2 6.4 0.0014 17.8 0.0 4.2 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 EMC99774.1 - 0.00077 19.6 1.1 16 5.7 0.0 5.4 3 2 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EMC99774.1 - 0.0011 18.6 0.1 7.9 6.0 0.0 4.8 4 1 0 5 5 5 1 CLASP N terminal Tti2 PF10521.9 EMC99774.1 - 0.0032 17.1 0.8 1.9 7.9 0.0 3.7 3 1 0 3 3 3 1 Tti2 family Cohesin_HEAT PF12765.7 EMC99774.1 - 0.0045 17.3 0.5 0.32 11.4 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.7 EMC99774.1 - 0.0047 16.8 0.7 2.4 8.0 0.1 3.8 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TIP120 PF08623.10 EMC99774.1 - 0.019 14.8 2.8 3.2 7.5 0.1 4.4 2 2 2 4 4 4 0 TATA-binding protein interacting (TIP20) NUC173 PF08161.12 EMC99774.1 - 0.042 13.5 0.7 11 5.6 0.0 4.3 3 1 1 4 4 4 0 NUC173 domain ParA PF10609.9 EMC99775.1 - 1e-94 316.6 0.0 1.2e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EMC99775.1 - 7.9e-13 48.6 0.0 1.5e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EMC99775.1 - 4.4e-08 33.2 0.8 3.3e-07 30.4 0.3 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EMC99775.1 - 2.4e-05 23.8 0.2 5.7e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 EMC99775.1 - 0.0049 16.5 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EMC99775.1 - 0.01 15.0 1.2 0.084 12.0 0.5 2.4 3 1 0 3 3 3 0 Anion-transporting ATPase Fer4_NifH PF00142.18 EMC99775.1 - 0.019 14.5 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 EMC99775.1 - 0.031 14.1 0.4 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EMC99775.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zn-ribbon_8 PF09723.10 EMC99775.1 - 0.22 11.7 0.3 0.39 10.9 0.3 1.3 1 0 0 1 1 1 0 Zinc ribbon domain Rick_17kDa_Anti PF05433.15 EMC99776.1 - 0.01 15.7 13.0 0.02 14.8 13.0 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 EMC99776.1 - 0.021 14.5 9.8 0.038 13.7 9.8 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF456 PF04306.13 EMC99776.1 - 0.031 14.6 0.5 0.043 14.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 EMC99776.1 - 0.17 11.9 12.7 0.46 10.5 12.7 1.6 1 1 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.9 EMC99776.1 - 0.26 11.4 9.3 0.44 10.7 9.3 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Epimerase PF01370.21 EMC99777.1 - 6.3e-09 35.7 0.8 4.4e-07 29.6 0.8 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC99777.1 - 4.4e-05 23.5 0.2 0.0001 22.2 0.2 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EMC99777.1 - 0.00026 20.2 0.0 0.00042 19.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EMC99777.1 - 0.00037 20.1 0.4 0.0017 18.0 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EMC99777.1 - 0.00074 19.8 0.7 0.0015 18.8 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EMC99777.1 - 0.0023 17.4 0.7 0.23 10.8 0.2 2.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMC99777.1 - 0.0026 16.8 0.8 0.039 12.9 0.8 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EMC99777.1 - 0.015 15.9 0.1 0.1 13.2 0.0 2.5 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EMC99777.1 - 0.13 12.7 0.0 0.37 11.3 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FMO-like PF00743.19 EMC99778.1 - 6.2e-19 67.8 0.0 1.2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EMC99778.1 - 1.7e-14 53.8 0.0 3.4e-14 52.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC99778.1 - 3.9e-09 36.2 0.0 2.9e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMC99778.1 - 3.1e-07 30.5 0.0 1.6e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EMC99778.1 - 6.3e-06 25.6 0.2 5.4e-05 22.5 0.1 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMC99778.1 - 0.005 16.8 0.0 0.43 10.6 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMC99778.1 - 0.006 17.1 0.0 0.32 11.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMC99778.1 - 0.02 14.0 0.1 0.041 12.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 EMC99778.1 - 0.043 13.1 0.1 0.44 9.7 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 EMC99778.1 - 0.065 12.6 0.5 0.43 9.9 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EMC99778.1 - 0.13 11.2 0.0 0.5 9.4 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EMC99778.1 - 0.28 10.7 4.2 0.61 9.6 0.5 3.0 2 2 1 3 3 3 0 FAD dependent oxidoreductase ATG13 PF10033.9 EMC99779.1 - 1.5e-54 185.2 0.0 2.3e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 NmrA PF05368.13 EMC99780.1 - 5.5e-36 124.3 0.0 6.8e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMC99780.1 - 4.9e-16 59.2 0.0 7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMC99780.1 - 1.6e-07 31.0 0.1 2.1e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMC99780.1 - 8e-05 22.2 0.9 0.00017 21.1 0.9 1.5 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 EMC99780.1 - 0.00026 21.2 0.1 0.00048 20.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.17 EMC99780.1 - 0.002 17.3 0.1 0.0032 16.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EMC99780.1 - 0.002 17.6 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EMC99780.1 - 0.011 16.0 0.1 0.025 14.9 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 EMC99780.1 - 0.015 14.9 0.7 0.023 14.2 0.7 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 EMC99780.1 - 0.021 15.0 0.1 0.051 13.8 0.1 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 EMC99780.1 - 0.024 13.6 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EMC99780.1 - 0.03 14.9 0.3 0.073 13.7 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EMC99780.1 - 0.071 13.0 0.7 0.15 11.9 0.5 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 EMC99780.1 - 0.074 13.0 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 KR domain DFP PF04127.15 EMC99780.1 - 0.17 11.7 0.7 0.45 10.3 0.1 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein DUF748 PF05359.11 EMC99782.1 - 0.035 14.3 0.7 0.25 11.5 0.3 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF748) ACR_tran PF00873.19 EMC99782.1 - 0.15 9.7 5.5 0.27 8.9 5.5 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Fib_alpha PF08702.10 EMC99782.1 - 0.29 11.3 11.8 0.6 10.3 3.6 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family SURF6 PF04935.12 EMC99782.1 - 0.37 10.6 5.3 2.6 7.8 0.3 2.7 2 1 0 2 2 2 0 Surfeit locus protein 6 Baculo_PEP_C PF04513.12 EMC99782.1 - 0.4 10.7 16.6 0.47 10.5 0.6 4.1 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 EMC99782.1 - 0.4 9.9 12.0 1.3 8.3 2.5 3.4 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein THOC7 PF05615.13 EMC99782.1 - 0.55 10.5 12.4 0.083 13.2 5.8 2.9 2 2 1 3 3 3 0 Tho complex subunit 7 Serine_rich PF08824.10 EMC99782.1 - 2 8.4 11.4 14 5.6 0.2 4.0 2 1 1 4 4 4 0 Serine rich protein interaction domain CytochromB561_N PF09786.9 EMC99782.1 - 2.6 7.0 8.7 0.61 9.0 0.1 2.1 2 0 0 2 2 2 0 Cytochrome B561, N terminal PP_kinase_N PF13089.6 EMC99782.1 - 2.7 8.4 9.3 0.47 10.8 2.0 3.0 3 0 0 3 3 3 0 Polyphosphate kinase N-terminal domain Prominin PF05478.11 EMC99782.1 - 3.8 5.4 12.8 2.8 5.8 4.4 2.3 1 1 0 2 2 2 0 Prominin BLOC1_2 PF10046.9 EMC99782.1 - 4.7 7.6 12.2 4.8 7.6 3.0 3.8 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phasin_2 PF09361.10 EMC99782.1 - 5.2 7.4 21.9 5.9 7.2 11.0 4.1 4 1 0 4 4 4 0 Phasin protein Integrin_alpha PF00357.20 EMC99783.1 - 5.4 7.3 7.2 1.8 8.8 3.1 2.4 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region PMSR PF01625.21 EMC99784.1 - 6.6e-63 211.5 0.3 8e-63 211.2 0.3 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Asp PF00026.23 EMC99786.1 - 2.9e-16 59.8 0.1 3.8e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Glycophorin_A PF01102.18 EMC99786.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Glycophorin A DUF2207 PF09972.9 EMC99786.1 - 0.017 13.9 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VSP PF03302.13 EMC99786.1 - 0.036 12.9 1.6 0.051 12.4 1.6 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.11 EMC99786.1 - 0.04 14.0 0.2 0.075 13.1 0.2 1.3 1 0 0 1 1 1 0 Podoplanin TAXi_N PF14543.6 EMC99786.1 - 0.097 12.9 0.3 0.38 11.0 0.3 2.0 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal CD99L2 PF12301.8 EMC99786.1 - 0.22 11.8 5.0 3.3 8.0 0.1 2.2 1 1 1 2 2 2 0 CD99 antigen like protein 2 SH3_9 PF14604.6 EMC99788.1 - 8.7e-14 51.1 0.1 9.5e-14 51.0 0.1 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EMC99788.1 - 1.1e-13 50.5 0.0 1.2e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EMC99788.1 - 3.2e-07 29.9 0.0 3.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain DUF3253 PF11625.8 EMC99789.1 - 4.1e-31 107.1 0.1 4.5e-31 106.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) DUF2231 PF09990.9 EMC99790.1 - 4.2e-07 30.3 0.5 6.7e-07 29.7 0.5 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) Fungal_trans PF04082.18 EMC99791.1 - 1.1e-17 63.9 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC99791.1 - 3.9e-08 33.3 10.1 6.7e-08 32.5 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cnn_1N PF07989.11 EMC99791.1 - 0.015 15.4 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CGI-121 PF08617.10 EMC99792.1 - 5.1e-48 163.3 0.0 5.7e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 LYRIC PF15686.5 EMC99793.1 - 0.017 14.7 0.1 0.018 14.6 0.1 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family MSP1a PF11670.8 EMC99793.1 - 0.17 11.1 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Isochorismatase PF00857.20 EMC99796.1 - 2.4e-24 86.4 0.1 3.8e-24 85.8 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family Oxysterol_BP PF01237.18 EMC99800.1 - 1.2e-88 297.5 4.0 4.6e-79 266.0 0.0 2.3 2 1 1 3 3 3 2 Oxysterol-binding protein Cys_Met_Meta_PP PF01053.20 EMC99801.1 - 1e-58 198.7 0.0 2.8e-58 197.3 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EMC99801.1 - 0.0024 16.9 0.0 0.0043 16.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EMC99801.1 - 0.048 12.8 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Pro_isomerase PF00160.21 EMC99803.1 - 4e-44 150.7 0.5 5.8e-44 150.2 0.5 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 EMC99804.1 - 1.3e-47 160.9 0.6 1.8e-47 160.4 0.6 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EMC99804.1 - 0.00018 20.6 0.0 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 EMC99804.1 - 0.047 13.7 9.3 0.7 9.9 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5102) VHS PF00790.19 EMC99804.1 - 0.077 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 VHS domain C2 PF00168.30 EMC99805.1 - 3.8e-74 245.5 0.3 3.3e-20 72.3 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EMC99805.1 - 6.6e-07 29.0 0.0 1.4e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MLVIN_C PF18697.1 EMC99805.1 - 0.31 11.2 1.6 3.8 7.7 0.1 3.2 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain SHQ1 PF04925.15 EMC99806.1 - 0.095 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 SHQ1 protein adh_short PF00106.25 EMC99807.1 - 6.6e-32 110.5 0.2 1e-31 109.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99807.1 - 5.1e-22 78.6 0.1 6.4e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC99807.1 - 1.2e-08 35.1 0.1 1.7e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EMC99807.1 - 0.00011 21.7 1.0 0.0015 18.0 1.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMC99807.1 - 0.00033 20.2 0.7 0.00091 18.8 0.7 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC99807.1 - 0.00057 19.8 0.6 0.0011 18.9 0.6 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EMC99807.1 - 0.022 15.0 0.1 0.049 13.9 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EMC99807.1 - 0.024 13.8 0.8 0.076 12.1 0.8 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FolB PF02152.18 EMC99811.1 - 2.8e-21 76.1 0.0 1.2e-16 61.2 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase UDPGP PF01704.18 EMC99812.1 - 1.2e-190 633.6 0.0 1.5e-190 633.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 EMC99812.1 - 0.5 9.1 3.3 3.6 6.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) Acyl-CoA_dh_1 PF00441.24 EMC99813.1 - 2.7e-33 115.3 1.2 4.1e-33 114.7 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMC99813.1 - 1.4e-21 77.3 0.1 5.6e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EMC99813.1 - 1.5e-19 70.0 0.0 2.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMC99813.1 - 5.4e-10 39.7 0.1 9.8e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.20 EMC99813.1 - 0.097 13.2 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase CoA_transf_3 PF02515.17 EMC99814.1 - 2.2e-126 421.9 0.0 2.5e-126 421.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Pribosyltran PF00156.27 EMC99816.1 - 1.5e-12 47.3 0.0 2.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMC99816.1 - 0.017 14.5 0.0 0.039 13.4 0.0 1.5 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Lactamase_B PF00753.27 EMC99817.1 - 6.4e-09 36.1 2.6 9.6e-09 35.5 2.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMC99817.1 - 7.6e-05 22.3 0.1 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_1 PF00561.20 EMC99818.1 - 1.8e-10 40.9 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMC99818.1 - 1.9e-07 30.6 0.0 3.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMC99818.1 - 0.0015 19.2 0.0 0.0016 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family P53 PF00870.18 EMC99818.1 - 0.089 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 P53 DNA-binding domain ING PF12998.7 EMC99819.1 - 2e-16 60.4 0.1 2.9e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EMC99819.1 - 1.7e-05 24.6 10.3 3.5e-05 23.6 10.3 1.5 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.13 EMC99819.1 - 0.00028 21.0 2.6 0.00039 20.5 2.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-HC5HC2H PF13771.6 EMC99819.1 - 0.0021 18.2 1.0 0.0021 18.2 1.0 1.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain Arfaptin PF06456.13 EMC99819.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Arfaptin-like domain DUF3827 PF12877.7 EMC99819.1 - 4.9 5.4 6.3 0.26 9.6 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) Hist_deacetyl PF00850.19 EMC99820.1 - 3e-73 247.0 0.0 3.7e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain AAA PF00004.29 EMC99821.1 - 1.2e-17 64.5 0.0 2.6e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EMC99821.1 - 9.9e-05 22.6 3.4 0.0038 17.5 0.0 3.3 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 EMC99821.1 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMC99821.1 - 0.0035 17.8 0.1 0.013 15.9 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EMC99821.1 - 0.005 16.8 0.1 0.015 15.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EMC99821.1 - 0.015 15.7 0.1 0.053 13.9 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EMC99821.1 - 0.023 14.8 0.6 0.063 13.4 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 EMC99821.1 - 0.03 14.9 0.0 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EMC99821.1 - 0.034 13.9 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 EMC99821.1 - 0.036 14.0 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EMC99821.1 - 0.06 12.7 0.3 0.73 9.2 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI bZIP_1 PF00170.21 EMC99822.1 - 9.1e-07 28.9 6.6 1.3e-06 28.4 6.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMC99822.1 - 1.3e-06 28.4 13.6 1.8e-06 27.9 13.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMC99822.1 - 0.00014 22.3 3.8 0.00019 21.9 3.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor eIF3_subunit PF08597.10 EMC99822.1 - 1.6 8.6 7.5 2.1 8.2 7.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Glyco_hydro_16 PF00722.21 EMC99824.1 - 6.5e-43 146.3 6.1 1.1e-42 145.5 6.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EMC99824.1 - 0.044 14.3 14.3 0.1 13.1 14.3 1.6 1 0 0 1 1 1 0 Chitin recognition protein adh_short PF00106.25 EMC99825.1 - 2.2e-27 95.8 0.3 7.1e-27 94.1 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMC99825.1 - 1.3e-17 64.1 0.8 3.9e-17 62.6 0.8 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMC99825.1 - 5.4e-07 29.7 0.1 9.6e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Phage_TTP_12 PF16461.5 EMC99826.1 - 0.2 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP Helo_like_N PF17111.5 EMC99827.1 - 5e-06 26.0 1.1 5e-06 26.0 1.1 1.8 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins Alpha-E PF04168.12 EMC99827.1 - 0.0093 15.8 5.5 0.031 14.1 0.3 2.3 1 1 1 2 2 2 1 A predicted alpha-helical domain with a conserved ER motif. PI3K_P85_iSH2 PF16454.5 EMC99827.1 - 0.011 15.4 1.9 0.011 15.4 1.9 2.1 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Laminin_II PF06009.12 EMC99827.1 - 0.032 14.3 1.9 3.3 7.7 0.1 2.6 1 1 1 2 2 2 0 Laminin Domain II SesA PF17107.5 EMC99827.1 - 0.12 12.6 2.6 0.13 12.5 0.7 1.9 1 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CorA PF01544.18 EMC99827.1 - 0.51 9.6 4.1 0.72 9.1 4.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4600 PF15372.6 EMC99827.1 - 0.55 10.7 6.7 0.29 11.6 3.9 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4600) HMG-CoA_red PF00368.18 EMC99829.1 - 2.2e-143 477.8 4.0 2.7e-143 477.4 4.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EMC99829.1 - 9.1e-41 139.3 0.0 1.6e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EMC99829.1 - 5.4e-13 49.1 0.6 1.4e-12 47.7 0.6 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EMC99829.1 - 7.8e-06 24.3 1.2 1.2e-05 23.6 1.2 1.2 1 0 0 1 1 1 1 Patched family GIT_SHD PF08518.11 EMC99831.1 - 4.9e-22 77.2 9.1 4.6e-11 42.1 2.2 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT THP2 PF09432.10 EMC99831.1 - 0.0023 18.0 6.4 0.0023 18.0 6.4 3.1 3 0 0 3 3 3 1 Tho complex subunit THP2 Filament PF00038.21 EMC99831.1 - 0.0058 16.2 15.9 0.0058 16.2 15.9 3.2 1 1 2 3 3 3 2 Intermediate filament protein DUF3584 PF12128.8 EMC99831.1 - 0.37 8.2 43.8 0.54 7.7 43.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 EMC99831.1 - 1.5 9.0 52.0 6 7.0 15.4 4.0 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Macoilin PF09726.9 EMC99831.1 - 2 6.9 39.3 0.58 8.6 32.0 2.2 1 1 1 2 2 2 0 Macoilin family MscS_porin PF12795.7 EMC99831.1 - 4.4 6.8 50.7 4 6.9 1.8 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Spc7 PF08317.11 EMC99831.1 - 5 5.9 45.5 1.7 7.4 17.6 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_tail_APC PF16778.5 EMC99831.1 - 6.1 6.8 6.8 0.83 9.6 1.2 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein DUF3605 PF12239.8 EMC99832.1 - 3.3e-55 186.6 0.5 4.2e-55 186.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Transp_cyt_pur PF02133.15 EMC99833.1 - 1.2e-43 149.5 44.3 1.5e-43 149.2 44.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pro_dh PF01619.18 EMC99835.1 - 1.7e-64 218.2 0.9 2.2e-64 217.8 0.9 1.1 1 0 0 1 1 1 1 Proline dehydrogenase SprT-like PF10263.9 EMC99838.1 - 0.00016 21.5 0.1 0.00053 19.8 0.1 1.8 1 1 0 1 1 1 1 SprT-like family DUF4344 PF14247.6 EMC99838.1 - 0.033 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase Peptidase_M50B PF13398.6 EMC99838.1 - 0.16 11.6 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like TFR_dimer PF04253.15 EMC99839.1 - 1.1e-29 103.0 0.0 1.8e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EMC99839.1 - 3.9e-19 69.1 0.3 2.6e-18 66.4 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EMC99839.1 - 3.6e-09 36.5 0.0 1.3e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 PA domain Nicastrin PF05450.15 EMC99839.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Nicastrin adh_short_C2 PF13561.6 EMC99840.1 - 2.1e-60 204.2 1.4 2.5e-60 204.0 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMC99840.1 - 9.7e-41 139.4 1.3 1.2e-40 139.1 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMC99840.1 - 5.5e-14 52.5 0.6 8.1e-14 51.9 0.6 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 EMC99840.1 - 0.014 15.3 0.2 0.04 13.8 0.1 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus SNF2_N PF00176.23 EMC99844.1 - 1.7e-46 158.6 0.0 2.5e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EMC99844.1 - 2.4e-22 78.8 2.6 5.9e-22 77.6 2.6 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EMC99844.1 - 7.3e-19 68.2 0.0 1.6e-17 63.8 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMC99844.1 - 2e-06 27.9 0.0 5.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMC99844.1 - 3.1e-05 23.3 0.1 6.1e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SEC-C PF02810.15 EMC99844.1 - 1.8 8.6 7.4 3.6 7.6 7.4 1.6 1 0 0 1 1 1 0 SEC-C motif RNase_PH PF01138.21 EMC99845.1 - 8.2e-35 120.2 0.1 1.3e-34 119.6 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 CDH-cyt PF16010.5 EMC99846.1 - 8.9e-18 64.6 0.4 2.6e-17 63.1 0.4 1.7 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EMC99846.1 - 2.4e-08 34.2 7.7 4.7e-08 33.3 7.7 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EMC99846.1 - 4.5e-07 30.1 0.0 9.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 EMC99846.1 - 0.0047 16.7 0.9 0.0047 16.7 0.9 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Sarcolipin PF05366.11 EMC99846.1 - 0.026 14.2 0.7 0.063 13.0 0.7 1.6 1 0 0 1 1 1 0 Sarcolipin LYRIC PF15686.5 EMC99846.1 - 0.034 13.7 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family SdpI PF13630.6 EMC99846.1 - 0.046 13.9 0.1 0.046 13.9 0.1 3.5 1 1 2 3 3 3 0 SdpI/YhfL protein family YfhO PF09586.10 EMC99846.1 - 0.067 11.4 1.9 0.12 10.6 1.9 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4079 PF13301.6 EMC99846.1 - 0.15 12.2 6.3 0.24 11.6 2.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) EphA2_TM PF14575.6 EMC99846.1 - 0.18 12.7 0.0 2.5 9.0 0.0 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_U4 PF03419.13 EMC99846.1 - 0.21 10.9 10.0 5.8 6.1 10.0 2.1 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF998 PF06197.13 EMC99846.1 - 1.1 8.8 8.6 2.3 7.8 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF998) CBP_BcsF PF11120.8 EMC99846.1 - 5.4 7.2 11.1 0.72 10.0 0.9 3.2 3 1 1 4 4 4 0 Cellulose biosynthesis protein BcsF His_Phos_2 PF00328.22 EMC99847.1 - 1.4e-40 139.8 0.0 5.1e-40 138.0 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RskA PF10099.9 EMC99848.1 - 0.00087 19.6 0.0 0.00094 19.5 0.0 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF3899 PF13038.6 EMC99848.1 - 0.013 16.0 0.1 0.35 11.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) DUF3040 PF11239.8 EMC99848.1 - 0.057 13.7 0.1 0.13 12.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Synaptobrevin PF00957.21 EMC99848.1 - 0.088 12.6 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Synaptobrevin SP_C-Propep PF08999.10 EMC99848.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF2207 PF09972.9 EMC99848.1 - 0.14 10.9 0.1 0.17 10.6 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2116 PF09889.9 EMC99848.1 - 0.59 10.2 2.2 1.1 9.2 2.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ribosomal_S14 PF00253.21 EMC99849.1 - 3.4e-14 52.3 1.2 3.8e-14 52.2 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-CCCH PF00642.24 EMC99850.1 - 2.8e-09 36.7 15.0 3e-07 30.2 2.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EMC99850.1 - 0.00031 20.5 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EMC99850.1 - 0.0042 17.8 2.2 0.5 11.1 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 EMC99850.1 - 0.0058 16.6 3.3 0.0058 16.6 3.3 2.5 2 0 0 2 2 2 1 Zinc finger domain SCRG1 PF15224.6 EMC99850.1 - 0.21 11.7 3.6 0.27 11.4 0.0 2.4 2 1 0 2 2 2 0 Scrapie-responsive protein 1 zf-CCCH_3 PF15663.5 EMC99850.1 - 0.4 10.9 7.1 0.12 12.6 0.9 2.5 2 1 0 2 2 2 0 Zinc-finger containing family FAD_binding_7 PF03441.14 EMC99851.1 - 9.9e-82 273.3 0.2 2e-81 272.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EMC99851.1 - 1e-39 136.2 0.0 1.6e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 EMC99851.1 - 0.042 14.4 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family DUF2769 PF10967.8 EMC99855.1 - 0.04 14.6 1.5 0.18 12.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2769) DZR PF12773.7 EMC99855.1 - 0.12 12.5 2.8 1.4 9.0 0.3 2.1 1 1 1 2 2 2 0 Double zinc ribbon Zn_ribbon_SprT PF17283.2 EMC99855.1 - 0.81 9.6 9.3 2 8.4 0.0 2.9 2 1 0 2 2 2 0 SprT-like zinc ribbon domain RNA_pol_Rpc34 PF05158.12 EMC99857.1 - 9e-59 199.5 0.0 1.1e-58 199.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 EMC99857.1 - 0.03 14.5 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC DUF4295 PF14128.6 EMC99857.1 - 0.11 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) TrmB PF01978.19 EMC99857.1 - 0.14 12.1 0.1 0.78 9.7 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Slx4 PF09494.10 EMC99859.1 - 6.6e-17 61.2 1.2 2.4e-16 59.4 1.2 2.0 1 1 0 1 1 1 1 Slx4 endonuclease ABC_tran PF00005.27 EMC99860.1 - 8.7e-47 159.1 0.0 6e-29 101.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EMC99860.1 - 1e-35 123.7 38.3 1.4e-20 74.1 13.5 4.1 5 0 0 5 5 4 3 ABC transporter transmembrane region SMC_N PF02463.19 EMC99860.1 - 1.5e-13 50.7 1.7 6.6e-06 25.7 0.1 4.2 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMC99860.1 - 1.6e-08 34.2 0.8 0.00025 20.7 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EMC99860.1 - 1.3e-07 32.4 0.2 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EMC99860.1 - 5.8e-07 29.9 0.1 0.073 13.3 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EMC99860.1 - 3.4e-06 27.1 0.0 0.43 10.3 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMC99860.1 - 3.6e-05 24.2 0.4 0.38 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 EMC99860.1 - 0.00033 19.8 0.0 0.7 8.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_15 PF13175.6 EMC99860.1 - 0.00043 20.1 0.2 0.062 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMC99860.1 - 0.0016 18.3 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 EMC99860.1 - 0.0031 17.6 0.4 0.0067 16.6 0.4 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EMC99860.1 - 0.0032 16.9 0.1 0.43 9.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 EMC99860.1 - 0.0077 16.0 0.5 1.5 8.5 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.6 EMC99860.1 - 0.0092 15.6 0.1 0.1 12.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EMC99860.1 - 0.014 15.5 0.0 0.93 9.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 EMC99860.1 - 0.016 14.8 1.1 2.9 7.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 EMC99860.1 - 0.016 15.4 0.0 6.8 7.0 0.0 3.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EMC99860.1 - 0.036 14.2 0.0 14 5.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMC99860.1 - 0.042 13.3 0.1 7.5 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_ATPase PF09818.9 EMC99860.1 - 0.048 12.4 1.1 0.16 10.7 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 EMC99860.1 - 0.055 12.7 0.0 15 4.8 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin Sigma54_activat PF00158.26 EMC99860.1 - 0.092 12.5 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Dynamin_N PF00350.23 EMC99860.1 - 0.14 12.2 0.0 8.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 EMC99860.1 - 0.23 11.2 0.9 8.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DEAD PF00270.29 EMC99860.1 - 0.41 10.4 2.5 32 4.2 2.6 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 EMC99860.1 - 1.3 9.0 3.4 23 4.9 0.1 3.5 4 0 0 4 4 3 0 NACHT domain PIF6 PF05341.11 EMC99862.1 - 0.18 12.0 0.2 0.31 11.2 0.2 1.3 1 0 0 1 1 1 0 Per os infectivity factor 6 Acetyltransf_7 PF13508.7 EMC99863.1 - 3.9e-05 24.0 0.0 6.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMC99863.1 - 0.00025 21.2 0.1 0.00045 20.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMC99863.1 - 0.0003 20.7 0.7 0.0034 17.3 0.5 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ssu72 PF04722.13 EMC99864.1 - 1.2e-81 272.9 0.0 1.3e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein FYVE PF01363.21 EMC99865.1 - 1.2e-14 54.2 1.5 1.2e-14 54.2 1.5 3.3 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EMC99865.1 - 2.7e-08 34.0 17.4 6.6e-07 29.6 3.9 3.6 3 0 0 3 3 3 2 Ring finger domain Rad50_zn_hook PF04423.14 EMC99865.1 - 0.00032 20.5 4.0 0.17 11.7 0.5 2.3 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C3HC4 PF00097.25 EMC99865.1 - 0.00053 19.8 1.5 0.00053 19.8 1.5 4.0 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EMC99865.1 - 0.00062 19.6 2.9 0.00062 19.6 2.9 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EMC99865.1 - 0.00073 19.2 4.5 0.00073 19.2 4.5 3.0 3 0 0 3 3 3 1 RING-like zinc finger FANCL_C PF11793.8 EMC99865.1 - 0.023 14.9 3.5 0.023 14.9 3.5 2.9 3 0 0 3 3 3 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EMC99865.1 - 0.024 14.3 3.6 0.024 14.3 3.6 2.9 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EMC99865.1 - 0.046 14.0 2.7 0.046 14.0 2.7 3.2 3 1 1 4 4 3 0 RING-like domain Prok-RING_1 PF14446.6 EMC99865.1 - 0.17 11.8 16.6 0.58 10.1 2.4 4.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 DZR PF12773.7 EMC99865.1 - 0.2 11.7 10.8 0.77 9.8 0.2 3.3 3 0 0 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EMC99865.1 - 0.6 9.6 6.7 5.2 6.6 0.3 3.9 3 0 0 3 3 3 0 zinc-ribbon domain RINGv PF12906.7 EMC99865.1 - 0.87 9.8 13.0 0.048 13.8 4.3 2.9 3 0 0 3 3 2 0 RING-variant domain Aldedh PF00171.22 EMC99866.1 - 1.1e-131 439.5 0.9 1.3e-131 439.4 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EMC99866.1 - 0.00039 19.9 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Fungal_trans PF04082.18 EMC99867.1 - 7e-13 48.2 0.0 1.2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC99867.1 - 2.1e-05 24.5 13.5 3.7e-05 23.8 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5127 PF17168.4 EMC99870.1 - 4.8e-84 281.7 11.5 7.5e-84 281.0 11.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EMC99870.1 - 6.6e-65 218.0 1.0 1.5e-64 216.8 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EMC99870.1 - 1.2e-63 214.6 0.3 1.2e-63 214.6 0.3 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EMC99870.1 - 1.3e-06 27.9 0.1 3.1e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) RibD_C PF01872.17 EMC99871.1 - 6.4e-31 107.7 0.0 9.3e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain GFA PF04828.14 EMC99872.1 - 7.4e-20 71.1 0.1 7.4e-20 71.1 0.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2 PF00096.26 EMC99873.1 - 2.1e-05 24.7 27.7 0.017 15.6 0.2 5.8 4 2 1 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMC99873.1 - 0.00071 20.2 26.5 0.17 12.8 0.2 5.8 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMC99873.1 - 0.11 12.8 14.4 1.6 9.1 0.2 4.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EMC99873.1 - 1.1 10.0 5.4 0.18 12.5 0.3 2.4 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 EMC99873.1 - 4.2 7.9 11.0 8.2 7.0 0.2 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EMC99873.1 - 6.9 7.3 13.8 8.8 7.0 0.2 4.7 4 0 0 4 4 4 0 Zinc-finger double domain CBM26 PF16738.5 EMC99874.1 - 0.11 12.7 0.6 0.31 11.3 0.2 1.9 2 0 0 2 2 2 0 Starch-binding module 26 SLT PF01464.20 EMC99875.1 - 0.0094 15.6 0.4 0.017 14.8 0.4 1.4 1 1 0 1 1 1 1 Transglycosylase SLT domain DUF5427 PF10310.9 EMC99878.1 - 1.2e-160 535.5 0.1 1.4e-160 535.3 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 EMC99878.1 - 0.013 15.7 1.5 0.034 14.4 0.4 2.2 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain DUF2076 PF09849.9 EMC99878.1 - 0.7 9.9 9.9 1.3 9.0 9.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ADH_zinc_N PF00107.26 EMC99879.1 - 4.8e-12 46.0 0.2 9.1e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMC99879.1 - 1.3e-08 34.6 0.4 3.8e-08 33.2 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMC99879.1 - 0.014 16.4 0.0 0.024 15.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3405 PF11885.8 EMC99880.1 - 1.1e-198 661.1 18.8 6.9e-196 651.8 18.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) DUF4407 PF14362.6 EMC99881.1 - 0.0022 17.4 4.0 0.0043 16.4 4.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Cortex-I_coil PF09304.10 EMC99881.1 - 0.0025 18.0 11.1 0.0044 17.2 3.4 2.6 1 1 1 2 2 2 1 Cortexillin I, coiled coil DUF812 PF05667.11 EMC99881.1 - 0.0043 16.0 1.9 0.0076 15.2 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Laminin_II PF06009.12 EMC99881.1 - 0.17 11.9 5.0 0.16 12.0 1.5 2.4 1 1 1 2 2 2 0 Laminin Domain II CCDC-167 PF15188.6 EMC99881.1 - 0.32 11.4 7.6 1.2 9.5 1.7 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF745 PF05335.13 EMC99881.1 - 0.37 10.5 8.1 0.058 13.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 EMC99881.1 - 1.1 9.3 5.7 66 3.6 4.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 EMC99881.1 - 1.6 8.8 15.9 5.3 7.2 15.4 2.0 1 1 1 2 2 2 0 Tropomyosin like ADIP PF11559.8 EMC99881.1 - 1.8 8.7 11.4 0.25 11.4 2.4 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.6 EMC99881.1 - 2.2 8.0 8.0 12 5.5 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) BLOC1_2 PF10046.9 EMC99881.1 - 2.4 8.5 5.4 2.9 8.2 0.3 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 EMC99881.1 - 3.3 8.2 4.9 11 6.5 0.7 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Filament PF00038.21 EMC99881.1 - 3.8 7.0 16.6 23 4.4 5.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein Ax_dynein_light PF10211.9 EMC99881.1 - 5.8 6.8 10.9 7.8 6.4 1.8 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain Lectin_N PF03954.14 EMC99881.1 - 6.1 6.6 6.4 1.2 8.9 0.4 2.8 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Rho_Binding PF08912.11 EMC99881.1 - 6.3 7.7 7.3 4.3 8.2 0.9 2.6 2 0 0 2 2 2 0 Rho Binding TMF_TATA_bd PF12325.8 EMC99881.1 - 10 6.4 15.6 8.2 6.7 2.4 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Rick_17kDa_Anti PF05433.15 EMC99883.1 - 0.00018 21.3 5.7 0.00041 20.1 5.7 1.6 1 1 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EMC99883.1 - 0.00095 19.1 3.2 0.0019 18.1 3.2 1.5 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EMC99883.1 - 0.0023 17.6 6.4 0.0044 16.7 6.4 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF3225 PF11533.8 EMC99883.1 - 0.056 13.2 0.7 0.14 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) Menin PF05053.13 EMC99883.1 - 1.9 6.8 5.7 2.7 6.2 5.7 1.2 1 0 0 1 1 1 0 Menin Transgly_assoc PF04226.13 EMC99883.1 - 4.1 7.7 8.3 10 6.5 7.4 1.9 1 1 1 2 2 2 0 Transglycosylase associated protein IMPDH PF00478.25 EMC99884.1 - 1e-122 409.5 0.0 1.1e-121 406.1 0.0 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EMC99884.1 - 5.5e-18 65.2 0.0 1.2e-08 35.2 0.0 3.0 2 1 1 3 3 3 2 CBS domain FMN_dh PF01070.18 EMC99884.1 - 1.4e-08 34.2 0.8 3.1e-08 33.0 0.8 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EMC99884.1 - 2.3e-06 27.2 2.8 0.00037 20.0 3.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 EMC99884.1 - 0.00038 20.0 0.8 0.012 15.1 0.1 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 EMC99884.1 - 0.044 13.1 0.7 0.082 12.2 0.7 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG YpsA PF06908.11 EMC99884.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Aldolase PF01081.19 EMC99884.1 - 0.18 11.2 1.2 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 KDPG and KHG aldolase Glu_synthase PF01645.17 EMC99884.1 - 0.25 10.4 3.5 0.45 9.6 3.5 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Myb_DNA-bind_6 PF13921.6 EMC99887.1 - 1.6e-08 34.7 0.0 3.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EMC99887.1 - 0.00077 19.6 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIIA PF03153.13 EMC99887.1 - 8.1 6.3 16.5 8.4 6.3 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-binding PF00249.31 EMC99889.1 - 1.4e-13 50.7 1.1 3.4e-09 36.7 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMC99889.1 - 3.9e-08 33.4 0.5 0.00011 22.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EMC99889.1 - 0.015 15.1 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Myb DNA-binding like TFIIA PF03153.13 EMC99889.1 - 4.5 7.2 11.8 4.5 7.2 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF498 PF04430.14 EMC99890.1 - 1.1e-30 105.8 0.0 1.6e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) STAT1_TAZ2bind PF12162.8 EMC99890.1 - 0.12 12.0 0.7 0.2 11.2 0.7 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain PROCN PF08083.11 EMC99892.1 - 1.3e-234 778.4 7.5 1.3e-234 778.4 7.5 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EMC99892.1 - 1.2e-127 424.2 1.4 2.2e-127 423.4 1.4 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EMC99892.1 - 4.5e-88 293.2 1.8 1.6e-87 291.4 1.8 2.1 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EMC99892.1 - 1.8e-79 265.0 1.3 1.8e-79 265.0 1.3 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EMC99892.1 - 6.4e-71 236.7 0.1 1.3e-70 235.7 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EMC99892.1 - 5.4e-47 158.1 0.5 1.5e-46 156.7 0.5 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EMC99892.1 - 4.9e-41 139.5 0.1 1.6e-40 137.8 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain Ribosomal_L34e PF01199.18 EMC99893.1 - 1.1e-40 137.8 3.8 1.6e-40 137.3 3.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e DZR PF12773.7 EMC99893.1 - 0.0097 15.9 0.3 0.014 15.4 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon Bax1-I PF01027.20 EMC99895.1 - 1.9e-31 109.5 10.7 2.8e-31 109.0 10.7 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.16 EMC99896.1 - 6.6e-16 58.2 33.6 3.7e-11 42.6 19.3 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMC99896.1 - 2.8e-06 26.5 0.1 2.8e-06 26.5 0.1 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter TMEM208_SND2 PF05620.11 EMC99896.1 - 0.21 11.4 0.0 0.21 11.4 0.0 2.7 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Asn_synthase PF00733.21 EMC99897.1 - 3.3e-72 244.1 0.0 4.5e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EMC99897.1 - 3.7e-32 110.8 0.0 9.4e-32 109.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EMC99897.1 - 6.5e-29 100.8 0.0 2.3e-28 99.1 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EMC99897.1 - 0.0026 17.3 0.0 0.0083 15.6 0.0 1.7 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 EMC99897.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD synthase DUF3683 PF12447.8 EMC99897.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) DUF2427 PF10348.9 EMC99902.1 - 0.096 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Zn_clus PF00172.18 EMC99903.1 - 7.3e-07 29.2 6.7 1.6e-06 28.1 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMC99903.1 - 8.5e-05 21.7 0.4 0.00015 20.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3648 PF12364.8 EMC99903.1 - 0.11 12.7 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3648) T6SS_HCP PF05638.12 EMC99904.1 - 0.0002 21.8 0.0 0.00027 21.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp DUF5640 PF18692.1 EMC99904.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5640) Fungal_trans PF04082.18 EMC99905.1 - 1.6e-18 66.7 0.1 2.7e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMC99905.1 - 1.5e-08 34.6 11.4 3e-08 33.7 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EMC99906.1 - 2.4e-05 24.8 2.6 0.24 12.3 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EMC99906.1 - 0.23 11.8 1.7 0.55 10.6 1.2 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Aldose_epim PF01263.20 EMC99907.1 - 1.4e-52 178.9 0.9 1.7e-52 178.6 0.9 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_7 PF00840.20 EMC99908.1 - 1.7e-198 659.7 19.2 2.2e-198 659.3 19.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 EMC99908.1 - 1.6e-08 34.3 7.2 1.6e-08 34.3 7.2 5.9 4 1 0 4 4 4 1 Fungal cellulose binding domain Fucose_iso_C PF02952.17 EMC99908.1 - 0.063 13.0 0.7 0.16 11.6 0.7 1.7 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain Cu-oxidase_3 PF07732.15 EMC99909.1 - 5.8e-45 152.1 2.4 4.3e-44 149.3 0.4 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EMC99909.1 - 1.6e-32 112.1 9.6 3.4e-26 91.6 2.3 4.4 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 EMC99909.1 - 1.8e-31 109.4 0.1 1.1e-29 103.6 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase RRM_1 PF00076.22 EMC99912.1 - 1.1e-13 50.8 0.0 1.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EMC99912.1 - 0.033 14.2 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Lar_N PF09861.9 EMC99912.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Lactate racemase N-terminal domain LPMO_10 PF03067.15 EMC99914.1 - 0.5 11.0 4.9 0.6 10.7 4.9 1.4 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading HTH_IclR PF09339.10 EMC99915.1 - 0.22 11.3 3.3 0.2 11.5 1.8 1.6 1 1 0 1 1 1 0 IclR helix-turn-helix domain Hist_deacetyl PF00850.19 EMC99916.1 - 5.1e-81 272.5 0.1 1.1e-80 271.4 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 EMC99917.1 - 3.5e-32 110.8 0.0 5.8e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EMC99917.1 - 2.9e-12 47.0 0.4 6e-12 46.0 0.4 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EMC99917.1 - 3.2e-07 30.1 0.0 6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Fringe PF02434.16 EMC99918.1 - 2.2e-06 27.3 0.2 9.6e-05 21.9 0.1 2.8 2 1 0 2 2 2 1 Fringe-like PAN_1 PF00024.26 EMC99918.1 - 0.00087 19.2 0.3 0.0018 18.2 0.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 EMC99918.1 - 0.018 15.0 2.3 0.044 13.7 2.3 1.7 1 0 0 1 1 1 0 PAN domain AlphaC_C PF17480.2 EMC99918.1 - 0.12 12.4 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 AlphaC C-terminal DUF604 PF04646.12 EMC99918.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Pkinase PF00069.25 EMC99919.1 - 4.6e-68 229.4 0.0 7.9e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMC99919.1 - 2.1e-32 112.4 0.0 2.5e-31 108.9 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMC99919.1 - 0.011 15.1 0.9 3.2 7.0 0.0 2.8 3 0 0 3 3 3 0 Kinase-like Pkinase_fungal PF17667.1 EMC99919.1 - 0.051 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haem_degrading PF03928.14 EMC99920.1 - 5.6e-24 84.5 0.0 6.5e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading p450 PF00067.22 EMC99922.1 - 2.3e-31 109.0 0.0 3.3e-31 108.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 EMC99923.1 - 2.4e-08 34.0 11.6 3.7e-08 33.3 11.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMC99923.1 - 8.5e-07 28.1 0.8 1.1e-06 27.7 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NepR PF18557.1 EMC99923.1 - 0.15 11.7 1.0 0.36 10.5 1.0 1.6 1 0 0 1 1 1 0 Anti-sigma factor NepR RTA1 PF04479.13 EMC99924.1 - 7.6e-69 231.4 5.6 7.6e-69 231.4 5.6 1.4 2 0 0 2 2 2 1 RTA1 like protein Anp1 PF03452.14 EMC99925.1 - 2.7e-27 95.8 0.0 6.8e-27 94.5 0.0 1.7 1 1 0 1 1 1 1 Anp1 NTP_transf_3 PF12804.7 EMC99925.1 - 0.014 15.8 0.1 0.021 15.2 0.1 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain DAO PF01266.24 EMC99926.1 - 1.8e-22 80.5 0.1 4.3e-22 79.2 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMC99926.1 - 0.00019 21.6 1.3 0.0031 17.7 0.2 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EMC99926.1 - 0.0026 18.0 0.4 0.0086 16.3 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.27 EMC99926.1 - 0.0031 18.0 0.1 0.19 12.3 0.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMC99926.1 - 0.0044 16.3 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMC99926.1 - 0.0061 16.6 0.2 0.022 14.7 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding C1_1 PF00130.22 EMC99926.1 - 0.033 14.1 6.3 0.086 12.7 6.3 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FAD_binding_3 PF01494.19 EMC99926.1 - 0.057 12.6 0.5 0.49 9.6 0.5 2.1 1 1 0 1 1 1 0 FAD binding domain DUF1188 PF06690.11 EMC99926.1 - 0.19 11.3 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) K_oxygenase PF13434.6 EMC99926.1 - 0.21 10.7 0.2 1.2 8.2 0.1 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) C1_2 PF03107.16 EMC99926.1 - 0.43 10.9 11.7 0.039 14.3 5.0 2.6 2 1 1 3 3 3 0 C1 domain FYVE PF01363.21 EMC99926.1 - 0.69 10.1 9.2 0.027 14.6 3.0 2.0 2 0 0 2 2 2 0 FYVE zinc finger zf-B_box PF00643.24 EMC99926.1 - 0.76 10.0 10.3 0.15 12.2 6.1 2.0 2 0 0 2 2 2 0 B-box zinc finger p450 PF00067.22 EMC99927.1 - 7.8e-79 265.6 0.0 7.7e-78 262.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Spc7 PF08317.11 EMC99928.1 - 8.9e-05 21.5 5.3 8.9e-05 21.5 5.3 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein Fez1 PF06818.15 EMC99928.1 - 0.00061 20.3 0.7 0.0011 19.5 0.7 1.5 1 0 0 1 1 1 1 Fez1 Atg14 PF10186.9 EMC99928.1 - 0.0011 18.1 3.8 0.0022 17.1 3.8 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EMC99928.1 - 0.0012 18.9 12.5 0.0034 17.5 10.7 2.4 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding EzrA PF06160.12 EMC99928.1 - 0.0016 16.7 2.0 0.0022 16.3 2.0 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Lebercilin PF15619.6 EMC99928.1 - 0.0033 17.1 11.3 0.015 14.9 11.3 2.1 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.19 EMC99928.1 - 0.0043 16.9 9.2 0.0084 16.0 9.2 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Filament PF00038.21 EMC99928.1 - 0.0062 16.2 6.1 0.012 15.2 6.1 1.4 1 0 0 1 1 1 1 Intermediate filament protein AAA_13 PF13166.6 EMC99928.1 - 0.0072 15.0 1.6 0.01 14.6 1.6 1.1 1 0 0 1 1 1 1 AAA domain Macoilin PF09726.9 EMC99928.1 - 0.0078 14.8 5.3 0.011 14.3 5.3 1.2 1 0 0 1 1 1 1 Macoilin family ATG16 PF08614.11 EMC99928.1 - 0.01 16.1 10.0 0.01 16.1 10.0 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 EMC99928.1 - 0.011 15.9 1.4 0.011 15.9 1.4 2.4 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family Striatin PF08232.12 EMC99928.1 - 0.014 16.0 1.4 0.014 16.0 1.4 1.7 2 0 0 2 2 1 0 Striatin family DUF3584 PF12128.8 EMC99928.1 - 0.015 12.9 8.2 0.021 12.4 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IFT57 PF10498.9 EMC99928.1 - 0.016 14.2 2.9 0.024 13.6 2.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4335 PF14233.6 EMC99928.1 - 0.017 15.1 0.7 0.042 13.8 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) NPV_P10 PF05531.12 EMC99928.1 - 0.022 15.2 1.5 0.11 13.0 1.4 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 EMC99928.1 - 0.027 15.2 3.5 0.1 13.4 3.5 2.0 1 0 0 1 1 1 0 Occludin homology domain TMF_TATA_bd PF12325.8 EMC99928.1 - 0.033 14.4 2.6 0.093 13.0 2.6 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.15 EMC99928.1 - 0.034 13.7 13.1 0.11 12.1 13.0 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit HOOK PF05622.12 EMC99928.1 - 0.037 12.2 6.6 0.056 11.6 6.6 1.3 1 0 0 1 1 1 0 HOOK protein Gp58 PF07902.11 EMC99928.1 - 0.04 12.2 1.5 0.062 11.6 1.5 1.3 1 0 0 1 1 1 0 gp58-like protein FliJ PF02050.16 EMC99928.1 - 0.042 14.1 14.9 2.4 8.4 10.8 3.5 2 1 0 2 2 2 0 Flagellar FliJ protein UPF0242 PF06785.11 EMC99928.1 - 0.065 13.3 5.6 0.11 12.6 5.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2570 PF10828.8 EMC99928.1 - 0.073 12.9 6.2 0.42 10.4 6.7 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF2570) Bacillus_HBL PF05791.11 EMC99928.1 - 0.11 12.4 2.5 0.23 11.3 2.5 1.6 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) MAD PF05557.13 EMC99928.1 - 0.11 10.8 7.5 0.16 10.3 7.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Golgin_A5 PF09787.9 EMC99928.1 - 0.11 11.9 5.7 0.21 11.1 5.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 EMC99928.1 - 0.14 12.2 6.3 0.24 11.4 6.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.11 EMC99928.1 - 0.15 12.1 3.4 0.41 10.7 3.1 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.6 EMC99928.1 - 0.16 11.3 9.4 0.37 10.1 9.4 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding KxDL PF10241.9 EMC99928.1 - 0.18 12.1 5.7 0.19 12.1 2.4 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein Mod_r PF07200.13 EMC99928.1 - 0.22 11.6 10.1 0.62 10.2 8.0 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MPS2 PF17060.5 EMC99928.1 - 0.27 10.5 2.8 0.43 9.8 2.8 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 BLOC1_2 PF10046.9 EMC99928.1 - 0.33 11.3 6.4 6 7.2 4.4 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 EMC99928.1 - 0.38 9.3 2.0 0.64 8.6 2.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1515 PF07439.11 EMC99928.1 - 0.41 10.7 1.4 0.79 9.8 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF3450 PF11932.8 EMC99928.1 - 0.45 9.8 8.7 1.1 8.5 8.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 EMC99928.1 - 0.47 9.6 2.7 0.94 8.7 2.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF1043 PF06295.12 EMC99928.1 - 0.67 10.0 6.5 1.6 8.8 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FadA PF09403.10 EMC99928.1 - 0.75 10.3 5.7 8.9 6.9 5.7 2.4 1 1 1 2 2 2 0 Adhesion protein FadA Phage_GPO PF05929.11 EMC99928.1 - 1 8.9 5.4 2.3 7.8 5.4 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HIP1_clath_bdg PF16515.5 EMC99928.1 - 1.7 9.3 10.3 13 6.5 10.1 2.5 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 EMC99928.1 - 2 7.7 15.5 2.4 7.4 12.1 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EMC99928.1 - 2.3 8.5 9.2 6.3 7.1 9.2 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 EMC99928.1 - 2.5 8.1 7.8 0.62 10.1 0.5 2.6 2 1 1 3 3 2 0 Prefoldin subunit NPC1_N PF16414.5 EMC99929.1 - 1.4e-83 280.2 8.3 2.3e-83 279.5 8.3 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EMC99929.1 - 1.7e-76 258.0 1.4 5.1e-76 256.4 1.4 1.7 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EMC99929.1 - 4.7e-53 179.1 5.1 4.7e-53 179.1 5.1 3.7 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EMC99929.1 - 4.6e-05 22.5 12.2 4.6e-05 22.5 12.2 3.5 4 0 0 4 4 4 2 MMPL family Folate_rec PF03024.14 EMC99929.1 - 0.00036 20.5 2.6 0.00079 19.3 2.6 1.5 1 0 0 1 1 1 1 Folate receptor family Asparaginase_2 PF01112.18 EMC99930.1 - 1.9e-55 188.1 0.2 6.9e-48 163.2 0.0 3.1 2 1 0 2 2 2 2 Asparaginase DUF5619 PF18505.1 EMC99930.1 - 0.074 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) Proteasome PF00227.26 EMC99932.1 - 7.5e-60 201.7 0.1 9.3e-60 201.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EMC99932.1 - 4.3e-13 48.7 0.1 9.5e-13 47.6 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 EMC99932.1 - 0.0091 15.6 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 Nitrate reductase gamma subunit DUF5624 PF18538.1 EMC99932.1 - 0.045 13.9 0.3 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) FF PF01846.19 EMC99933.1 - 1.3e-08 34.9 7.7 1.6e-07 31.4 0.3 3.6 3 0 0 3 3 3 1 FF domain MHC_I PF00129.18 EMC99933.1 - 0.049 13.2 0.3 0.14 11.7 0.3 1.8 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 VGLL4 PF15245.6 EMC99933.1 - 0.24 11.5 0.8 0.47 10.5 0.8 1.4 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 HEPN_SAV_6107 PF18726.1 EMC99934.1 - 0.00051 20.5 0.1 0.0011 19.5 0.1 1.5 1 0 0 1 1 1 1 SAV_6107-like HEPN Wzy_C PF04932.15 EMC99934.1 - 0.42 10.2 10.1 3.4 7.3 2.6 2.8 2 1 0 2 2 2 0 O-Antigen ligase Phage_holin_4_1 PF05105.12 EMC99934.1 - 2.4 8.3 13.1 0.16 12.1 5.6 2.7 3 1 0 3 3 3 0 Bacteriophage holin family ABC2_membrane PF01061.24 EMC99936.1 - 1.1e-28 100.1 26.9 1.7e-28 99.5 26.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EMC99936.1 - 1.5e-25 90.3 0.0 2.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EMC99936.1 - 7.8e-06 25.9 0.2 5.6e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EMC99936.1 - 3.1e-05 23.6 0.1 6.6e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EMC99936.1 - 8.1e-05 22.6 0.5 0.31 10.8 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EMC99936.1 - 0.00079 19.8 0.1 0.0015 19.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EMC99936.1 - 0.00097 18.6 0.1 0.0046 16.4 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMC99936.1 - 0.0026 17.5 0.1 0.0055 16.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EMC99936.1 - 0.0033 17.7 0.0 0.011 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EMC99936.1 - 0.0089 16.1 0.6 0.069 13.2 0.1 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase Rad17 PF03215.15 EMC99936.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 EMC99936.1 - 0.048 12.7 0.2 0.082 11.9 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EMC99936.1 - 0.059 13.1 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EMC99936.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EMC99936.1 - 0.1 11.3 0.5 0.28 9.8 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMC99936.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EMC99936.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EMC99936.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_30 PF13604.6 EMC99936.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EMC99936.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF423 PF04241.15 EMC99936.1 - 0.68 10.2 6.0 12 6.2 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF423) Aminotran_5 PF00266.19 EMC99937.1 - 1e-25 90.5 0.0 7.6e-22 77.8 0.0 3.0 1 1 0 1 1 1 1 Aminotransferase class-V Zn_clus PF00172.18 EMC99938.1 - 1.2e-07 31.7 8.4 1.9e-07 31.1 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMC99938.1 - 4.3e-05 22.5 1.0 8.5e-05 21.5 0.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2797 PF10977.8 EMC99938.1 - 0.15 11.9 1.5 0.27 11.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) RTA1 PF04479.13 EMC99939.1 - 4.3e-70 235.5 9.2 4.3e-70 235.5 9.2 1.8 1 1 1 2 2 2 1 RTA1 like protein DUF5134 PF17197.4 EMC99939.1 - 0.026 14.4 0.8 0.026 14.4 0.8 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5134) BUD22 PF09073.10 EMC99940.1 - 1.3e-84 285.0 12.7 1.6e-84 284.7 12.7 1.1 1 0 0 1 1 1 1 BUD22 Sec3_C PF09763.9 EMC99941.1 - 3.5e-170 567.8 0.0 5.7e-170 567.1 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EMC99941.1 - 3.4e-27 94.4 0.0 6.6e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 EMC99941.1 - 0.023 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Vps52 PF04129.12 EMC99941.1 - 0.12 11.1 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 Vps52 / Sac2 family Ubie_methyltran PF01209.18 EMC99942.1 - 1.2e-74 250.6 0.0 1.7e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EMC99942.1 - 1.9e-16 60.5 0.0 3.7e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMC99942.1 - 1.2e-13 51.5 0.0 2.6e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMC99942.1 - 2.1e-12 47.1 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMC99942.1 - 6.9e-10 39.6 0.0 1.2e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMC99942.1 - 7.4e-08 32.4 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EMC99942.1 - 0.17 11.7 0.0 1.3 8.8 0.0 2.3 3 0 0 3 3 3 0 Hypothetical methyltransferase tRNA-synt_2b PF00587.25 EMC99943.1 - 4.1e-32 111.6 0.1 3.7e-30 105.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMC99943.1 - 6.4e-15 55.1 0.1 1.3e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EMC99943.1 - 1.4e-14 53.9 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EMC99943.1 - 3.1e-11 43.2 0.0 6.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain Ytp1 PF10355.9 EMC99944.1 - 1.2e-109 365.8 12.4 1.2e-109 365.8 12.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EMC99944.1 - 6.2e-26 90.2 3.6 6.2e-26 90.2 3.6 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) F-box-like PF12937.7 EMC99945.1 - 1.6e-08 34.3 0.0 3.5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMC99945.1 - 0.0037 17.1 0.1 0.01 15.7 0.1 1.8 2 0 0 2 2 2 1 F-box domain TPR_1 PF00515.28 EMC99945.1 - 0.032 14.1 0.1 2.2 8.3 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EMC99945.1 - 0.034 14.3 0.2 0.45 10.7 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EMC99945.1 - 0.053 13.2 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 TPR repeat Mito_carr PF00153.27 EMC99946.1 - 2e-61 203.9 1.6 8.1e-20 70.6 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMC99946.1 - 0.0073 15.5 2.4 0.028 13.6 0.0 2.6 3 0 0 3 3 3 1 Gammaproteobacterial serine protease Sugar_tr PF00083.24 EMC99948.1 - 4.9e-42 144.3 25.2 6.4e-42 144.0 25.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMC99948.1 - 5.4e-15 55.2 30.4 5.4e-15 55.2 30.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily BUD22 PF09073.10 EMC99949.1 - 0.0086 15.5 2.3 0.0089 15.4 2.3 1.1 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 EMC99949.1 - 0.096 12.1 6.4 0.11 12.0 6.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EMC99949.1 - 0.25 9.6 2.4 0.32 9.2 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EMC99949.1 - 0.37 8.8 12.1 0.47 8.5 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 EMC99949.1 - 1.1 9.3 8.5 1.5 8.9 8.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 EMC99949.1 - 1.1 8.9 9.6 0.15 11.8 3.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EMC99949.1 - 2.5 6.2 7.4 2.9 6.0 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family CBS PF00571.28 EMC99950.1 - 2.6e-11 43.8 1.5 3.1e-05 24.3 0.0 4.6 5 0 0 5 5 5 3 CBS domain CRAL_TRIO PF00650.20 EMC99951.1 - 3.4e-35 121.1 0.0 8.7e-35 119.8 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMC99951.1 - 3.1e-08 33.7 0.5 8e-08 32.4 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EMC99951.1 - 0.00071 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TLD PF07534.16 EMC99953.1 - 3.7e-25 88.8 0.0 1.6e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 TLD Sel1 PF08238.12 EMC99954.1 - 2.1e-16 60.0 26.4 7.7e-05 23.2 0.0 7.4 6 2 1 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 EMC99954.1 - 0.0031 17.3 1.4 0.052 13.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4244 PF14029.6 EMC99954.1 - 0.88 9.1 2.4 17 4.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) Glyco_hydro_72 PF03198.14 EMC99955.1 - 3.7e-132 440.4 9.7 4.8e-132 440.0 9.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EMC99955.1 - 4.7e-22 78.5 7.5 1.4e-21 76.9 7.5 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EMC99955.1 - 0.0018 17.8 2.7 0.0051 16.3 2.6 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EMC99955.1 - 0.008 15.3 0.2 0.012 14.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glucan_synthase PF02364.15 EMC99957.1 - 0 1384.8 0.0 0 1382.8 0.0 1.9 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EMC99957.1 - 1.1e-42 145.4 0.4 3.1e-42 143.9 0.4 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Fig1 PF12351.8 EMC99958.1 - 1.8e-58 197.6 2.0 1.8e-58 197.6 2.0 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EMC99958.1 - 2.2e-07 30.7 5.5 4.1e-07 29.9 5.5 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 EMC99958.1 - 0.0035 16.4 3.1 0.0035 16.4 3.1 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) PGG PF13962.6 EMC99958.1 - 0.013 15.3 2.5 0.03 14.1 2.3 1.8 1 1 0 1 1 1 0 Domain of unknown function FtsX PF02687.21 EMC99958.1 - 1.3 9.5 20.1 4.2 7.9 8.4 3.3 3 0 0 3 3 3 0 FtsX-like permease family DUF2207 PF09972.9 EMC99958.1 - 4.6 5.9 16.2 5.1 5.7 1.9 2.3 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) MLTD_N PF06474.12 EMC99958.1 - 9.9 6.4 6.4 5.5 7.3 3.0 2.3 2 0 0 2 2 2 0 MltD lipid attachment motif UCH PF00443.29 EMC99959.1 - 2.7e-53 181.1 0.2 3.6e-53 180.7 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EMC99959.1 - 3.2e-20 73.0 7.4 1.1e-18 68.0 7.4 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EMC99959.1 - 1.7e-06 28.2 0.7 1.7e-06 28.2 0.7 3.3 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 EMC99959.1 - 0.00025 20.6 4.7 0.28 10.6 0.2 3.2 3 1 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Piwi PF02171.17 EMC99960.1 - 1.4e-81 274.1 0.0 2.6e-81 273.2 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EMC99960.1 - 2.8e-19 70.1 0.0 5.9e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EMC99960.1 - 1.8e-17 62.7 0.2 6.2e-17 61.0 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 EMC99960.1 - 1.2e-15 57.5 0.5 2e-15 56.8 0.5 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 EMC99960.1 - 1.8e-10 41.0 0.0 8.8e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 EMC99960.1 - 3.2e-08 33.7 0.0 9.8e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ydhR PF08803.11 EMC99960.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR Suf PF05843.14 EMC99961.1 - 9.5e-65 219.5 7.9 6.9e-64 216.7 0.1 4.4 5 1 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EMC99961.1 - 1.4e-07 31.8 0.1 0.0053 17.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMC99961.1 - 0.018 15.5 0.3 26 5.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat P22_portal PF16510.5 EMC99961.1 - 0.042 12.5 0.2 0.072 11.7 0.2 1.3 1 0 0 1 1 1 0 Phage P22-like portal protein UNC-50 PF05216.13 EMC99962.1 - 2.9e-88 295.2 12.3 3.2e-88 295.0 12.3 1.0 1 0 0 1 1 1 1 UNC-50 family DUF962 PF06127.11 EMC99962.1 - 0.0028 17.7 0.3 3.1 7.9 0.0 3.5 1 1 2 3 3 3 2 Protein of unknown function (DUF962) ATG22 PF11700.8 EMC99963.1 - 7.3e-185 615.2 13.4 8.4e-185 615.0 13.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EMC99963.1 - 3.3e-05 23.0 49.0 0.0019 17.2 19.1 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMC99963.1 - 0.0054 15.3 32.8 0.0076 14.8 6.8 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein RRM_1 PF00076.22 EMC99964.1 - 1.3e-07 31.4 0.0 5.8e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EMC99964.1 - 1.4e-05 24.7 0.0 4.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.20 EMC99965.1 - 1.6e-20 73.2 0.1 2.1e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 RF-1 domain HLH PF00010.26 EMC99965.1 - 0.023 14.7 0.0 0.092 12.7 0.0 2.0 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain eIF2A PF08662.11 EMC99966.1 - 3.2e-82 275.1 0.1 1.7e-81 272.7 0.1 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EMC99966.1 - 0.0022 17.9 1.1 4.6 7.3 0.0 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 EMC99966.1 - 0.0033 18.2 0.7 4.7 8.3 0.1 4.4 3 2 0 3 3 3 1 WD domain, G-beta repeat Proteasome_A_N PF10584.9 EMC99966.1 - 0.37 10.5 1.2 29 4.5 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Importin_rep_4 PF18808.1 EMC99967.1 - 1.9e-32 111.4 4.6 4.3e-32 110.2 1.5 3.2 3 1 1 4 4 2 1 Importin repeat Importin_rep_5 PF18816.1 EMC99967.1 - 2.2e-23 82.3 1.3 1.5e-22 79.6 0.3 2.9 3 0 0 3 3 2 1 Importin repeat HEAT_EZ PF13513.6 EMC99967.1 - 2.6e-20 72.5 12.4 7.2e-11 42.4 0.3 8.3 9 1 1 10 10 8 2 HEAT-like repeat HEAT_2 PF13646.6 EMC99967.1 - 1.4e-14 54.3 18.8 1.4e-05 25.4 0.0 8.2 7 2 1 8 8 7 3 HEAT repeats HEAT PF02985.22 EMC99967.1 - 1.2e-13 50.0 10.9 0.0049 17.0 0.0 8.9 9 0 0 9 9 8 3 HEAT repeat Importin_rep_6 PF18829.1 EMC99967.1 - 1.2e-12 47.9 3.9 3.4e-12 46.4 0.5 3.3 3 0 0 3 3 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 EMC99967.1 - 2.1e-09 37.9 0.1 0.0076 16.8 0.0 5.7 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 EMC99967.1 - 5.4e-08 32.8 0.1 8.7e-05 22.3 0.0 4.0 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 EMC99967.1 - 8.8e-06 25.9 4.5 0.082 13.0 0.0 4.6 5 2 0 5 5 3 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EMC99967.1 - 9.3e-06 25.0 8.7 0.00012 21.3 1.0 3.8 3 2 1 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 EMC99967.1 - 1e-05 25.2 2.9 0.0016 18.1 0.1 4.4 3 2 1 4 4 4 1 CLASP N terminal DRIM PF07539.12 EMC99967.1 - 0.00011 20.6 4.8 0.013 13.8 0.2 3.9 2 1 1 3 3 3 1 Down-regulated in metastasis Arm PF00514.23 EMC99967.1 - 0.00043 20.2 6.0 0.016 15.2 0.1 4.3 4 0 0 4 4 3 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 EMC99967.1 - 0.00048 20.1 4.5 0.14 12.0 0.2 4.8 2 1 0 4 4 4 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 EMC99967.1 - 0.0055 15.3 4.2 0.011 14.3 0.0 3.2 4 1 1 5 5 5 1 Adaptin N terminal region Cnd3 PF12719.7 EMC99967.1 - 0.0088 15.3 0.0 0.16 11.1 0.0 2.9 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain DNA_alkylation PF08713.11 EMC99967.1 - 0.0091 15.7 0.1 0.081 12.6 0.0 2.6 3 0 0 3 3 3 1 DNA alkylation repair enzyme RTP1_C1 PF10363.9 EMC99967.1 - 0.013 15.6 4.9 15 5.8 0.0 4.7 5 1 0 6 6 4 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 EMC99967.1 - 0.016 14.8 6.9 0.23 11.0 0.1 4.2 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II V-ATPase_H_N PF03224.14 EMC99967.1 - 0.023 14.0 7.2 0.18 11.1 0.2 4.0 3 1 1 4 4 4 0 V-ATPase subunit H DUF4042 PF13251.6 EMC99967.1 - 0.033 13.9 0.1 5.9 6.5 0.0 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) TFCD_C PF12612.8 EMC99967.1 - 0.036 13.9 0.9 0.38 10.6 0.1 3.2 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal UNC45-central PF11701.8 EMC99967.1 - 0.06 13.3 3.6 1.7 8.6 0.1 3.0 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 EMC99967.1 - 0.07 13.1 3.1 3.6 7.5 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EMC99967.1 - 0.12 12.5 1.7 2.4 8.3 0.1 3.0 3 0 0 3 3 3 0 V-ATPase subunit H TAF6_C PF07571.13 EMC99967.1 - 0.12 12.7 1.1 5.9 7.3 0.0 3.6 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Symplekin_C PF12295.8 EMC99967.1 - 0.13 12.4 1.3 2.6 8.1 0.1 2.8 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal Glyco_hydro_16 PF00722.21 EMC99972.1 - 1.7e-34 118.8 4.4 3e-34 118.0 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Epimerase PF01370.21 EMC99973.1 - 1.7e-14 53.9 0.0 3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EMC99973.1 - 6.5e-13 49.0 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMC99973.1 - 1.1e-12 48.1 0.0 1.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EMC99973.1 - 2.2e-10 40.0 0.0 5.1e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EMC99973.1 - 4.5e-07 29.6 0.1 6.9e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EMC99973.1 - 0.00053 19.5 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EMC99973.1 - 0.00068 18.8 0.0 0.0081 15.3 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EMC99973.1 - 0.0011 18.2 0.1 0.056 12.6 0.0 2.5 1 1 0 2 2 2 1 Male sterility protein KR PF08659.10 EMC99973.1 - 0.017 15.0 0.0 2.6 7.9 0.0 2.4 3 0 0 3 3 3 0 KR domain Polysacc_synt_2 PF02719.15 EMC99973.1 - 0.048 12.8 0.0 0.1 11.7 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 EMC99973.1 - 0.059 12.9 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase eIF3_N PF09440.10 EMC99974.1 - 4.2e-46 156.7 3.1 8.1e-46 155.8 3.1 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EMC99974.1 - 2e-14 54.0 0.5 6.2e-14 52.4 0.0 2.1 3 0 0 3 3 3 1 PCI domain zf-H2C2 PF09337.10 EMC99975.1 - 1.4e-16 60.4 0.4 2.7e-16 59.5 0.4 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EMC99975.1 - 3.9e-11 42.9 0.2 6.8e-11 42.1 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EMC99975.1 - 0.0002 21.5 0.0 0.00048 20.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EMC99975.1 - 0.0033 17.6 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EMC99975.1 - 0.022 15.4 0.0 0.038 14.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Lgl_C PF08596.10 EMC99976.1 - 9.5e-118 393.3 0.0 1.5e-117 392.6 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EMC99976.1 - 8.6e-06 26.4 0.9 0.058 14.3 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMC99976.1 - 0.0019 18.5 0.0 8.4 6.8 0.0 4.2 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WSC PF01822.19 EMC99977.1 - 6.2e-13 48.8 12.7 6.2e-13 48.8 12.7 2.1 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 EMC99977.1 - 3.4e-08 32.8 4.8 9.3e-08 31.4 4.8 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 EMC99977.1 - 6e-05 23.2 5.8 0.00011 22.3 5.8 1.4 1 0 0 1 1 1 1 Podoplanin Stevor PF17410.2 EMC99977.1 - 0.00039 20.1 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame AJAP1_PANP_C PF15298.6 EMC99977.1 - 0.0088 16.3 11.6 0.015 15.6 11.6 1.3 1 0 0 1 1 1 1 AJAP1/PANP C-terminus DUF4448 PF14610.6 EMC99977.1 - 0.012 15.4 0.2 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 EMC99977.1 - 0.022 14.5 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF5326 PF17260.2 EMC99977.1 - 0.034 14.3 0.1 0.062 13.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) PTP_tm PF18861.1 EMC99977.1 - 0.035 14.1 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 EMC99977.1 - 0.036 14.9 0.0 0.074 13.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3042 PF11240.8 EMC99977.1 - 0.13 12.3 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF4381 PF14316.6 EMC99977.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2207 PF09972.9 EMC99977.1 - 0.2 10.4 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_2_4 PF16082.5 EMC99977.1 - 0.21 11.4 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 1 0 Bacteriophage holin family, superfamily II-like Syndecan PF01034.20 EMC99977.1 - 0.26 11.2 0.3 0.55 10.2 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain SSP160 PF06933.11 EMC99977.1 - 0.28 9.3 25.7 0.37 9.0 25.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAM53 PF15242.6 EMC99977.1 - 0.41 10.4 14.2 0.8 9.5 14.2 1.5 1 0 0 1 1 1 0 Family of FAM53 Hamartin PF04388.12 EMC99977.1 - 0.57 8.8 6.6 0.63 8.6 6.6 1.1 1 0 0 1 1 1 0 Hamartin protein Pex14_N PF04695.13 EMC99977.1 - 1.9 9.1 7.3 0.28 11.9 2.7 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pap_E4 PF02711.14 EMC99977.1 - 2.4 9.2 8.8 8.2 7.5 8.8 1.9 1 0 0 1 1 1 0 E4 protein Gram_pos_anchor PF00746.21 EMC99977.1 - 3.3 7.7 6.5 17 5.5 2.8 3.3 2 1 0 2 2 2 0 LPXTG cell wall anchor motif Ribosomal_L29e PF01779.17 EMC99978.1 - 1.1e-20 73.6 11.3 1.7e-20 73.1 11.3 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family CP2 PF04516.15 EMC99980.1 - 8.9e-80 267.3 0.0 1.3e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor zf-HIT PF04438.16 EMC99981.1 - 3.3e-09 36.4 7.0 5.2e-09 35.8 7.0 1.3 1 0 0 1 1 1 1 HIT zinc finger CBP_BcsO PF17037.5 EMC99981.1 - 0.012 15.8 5.8 0.027 14.7 5.8 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Abhydrolase_2 PF02230.16 EMC99982.1 - 1.4e-35 123.1 0.0 2.2e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EMC99982.1 - 0.004 16.5 0.1 2.7 7.2 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EMC99982.1 - 0.005 16.5 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 EMC99982.1 - 0.048 13.6 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.13 EMC99982.1 - 0.055 13.3 0.0 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 EMC99982.1 - 0.22 11.4 0.0 0.48 10.3 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MFS_1 PF07690.16 EMC99982.1 - 0.23 10.4 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily TBPIP PF07106.13 EMC99983.1 - 1.6e-15 56.7 1.0 2.5e-15 56.1 0.1 1.8 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Mto2_bdg PF12808.7 EMC99983.1 - 0.0055 17.0 2.0 0.79 10.1 0.0 3.1 3 0 0 3 3 3 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Penicillinase_R PF03965.16 EMC99983.1 - 0.0099 16.2 0.8 0.023 15.1 0.1 1.9 2 1 1 3 3 3 1 Penicillinase repressor DivIC PF04977.15 EMC99983.1 - 0.46 10.3 4.1 1.2 8.9 0.2 2.8 3 0 0 3 3 3 0 Septum formation initiator IalB PF06776.12 EMC99984.1 - 0.11 12.6 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 Invasion associated locus B (IalB) protein Mito_carr PF00153.27 EMC99985.1 - 9.4e-58 192.2 2.7 3.6e-21 74.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3348 PF11828.8 EMC99986.1 - 0.03 14.0 0.4 0.093 12.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) Ribosomal_S2 PF00318.20 EMC99987.1 - 3.5e-63 212.7 0.0 2.5e-62 209.9 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 ADIP PF11559.8 EMC99988.1 - 0.0053 16.9 3.2 0.0081 16.3 3.2 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding SH3BGR PF04908.15 EMC99988.1 - 0.14 12.4 0.7 0.22 11.7 0.7 1.3 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein HUN PF08729.10 EMC99989.1 - 2.7e-08 33.7 0.1 6.8e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain DUF5320 PF17253.2 EMC99989.1 - 2.9 9.0 7.2 2.9 9.0 5.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) RPAP1_C PF08620.10 EMC99990.1 - 1.3e-25 89.3 0.1 2.5e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EMC99990.1 - 3.5e-18 65.1 6.3 3.5e-18 65.1 6.3 1.8 2 0 0 2 2 2 1 RPAP1-like, N-terminal Rhomboid PF01694.22 EMC99991.1 - 7.6e-18 64.9 8.2 7.6e-18 64.9 8.2 1.4 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.14 EMC99992.1 - 2.5e-130 435.8 0.0 3.2e-130 435.5 0.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component SOG2 PF10428.9 EMC99993.1 - 1.9 7.6 12.0 2.3 7.3 12.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4062 PF13271.6 EMC99994.1 - 0.36 11.2 2.2 1 9.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4062) CtIP_N PF10482.9 EMC99994.1 - 0.88 9.6 11.9 0.038 14.0 1.3 3.2 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Phage_GP20 PF06810.11 EMC99994.1 - 2.9 7.7 6.7 0.59 9.9 1.7 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 FHA PF00498.26 EMC99995.1 - 2e-15 56.9 0.0 3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EMC99995.1 - 2.8e-06 27.6 0.1 0.00016 21.9 0.1 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CBM_6 PF03422.15 EMC99997.1 - 0.23 11.7 2.6 0.4 11.0 0.1 2.3 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) HSP9_HSP12 PF04119.12 EMC99998.1 - 4.3e-23 81.5 11.3 4.3e-23 81.5 11.3 1.5 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.7 EMC99998.1 - 0.56 10.8 3.2 1.7 9.2 3.2 1.9 1 1 0 1 1 1 0 YtxH-like protein AMMECR1 PF01871.17 EMD00001.1 - 7e-42 142.9 0.0 1.7e-41 141.6 0.0 1.7 1 1 0 1 1 1 1 AMMECR1 CDC45 PF02724.14 EMD00001.1 - 0.043 12.1 5.3 0.057 11.7 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 EMD00001.1 - 3.1 7.5 6.6 4.4 7.0 6.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NUP214 PF16755.5 EMD00002.1 - 1.6e-09 37.5 0.0 5.6e-09 35.7 0.0 1.8 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Golgin_A5 PF09787.9 EMD00002.1 - 1.6e-05 24.6 6.3 3.2e-05 23.6 6.3 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF2353 PF09789.9 EMD00002.1 - 0.0078 15.6 3.3 0.012 15.0 3.3 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ANAPC4_WD40 PF12894.7 EMD00002.1 - 0.0098 16.2 0.0 0.19 12.0 0.0 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cnn_1N PF07989.11 EMD00002.1 - 0.51 10.5 3.5 1 9.6 3.5 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 FUSC PF04632.12 EMD00002.1 - 1.6 7.2 7.5 2.7 6.4 7.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 EMD00002.1 - 4.9 7.2 5.7 18 5.3 4.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SDA1 PF05285.12 EMD00002.1 - 7.3 5.9 23.1 0.031 13.7 12.1 2.1 2 0 0 2 2 2 0 SDA1 Proteasome PF00227.26 EMD00003.1 - 2.4e-46 157.6 0.0 3.5e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EMD00003.1 - 8.9e-13 47.4 1.4 8.9e-13 47.4 1.4 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal DNA_ligase_A_M PF01068.21 EMD00004.1 - 1e-47 162.4 0.1 4.8e-45 153.7 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EMD00004.1 - 2.6e-36 125.5 0.1 5e-36 124.6 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EMD00004.1 - 5.3e-19 68.7 0.0 3.6e-18 66.0 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Methyltransf_15 PF09445.10 EMD00005.1 - 2.1e-50 170.6 0.0 2.8e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EMD00005.1 - 4.2e-09 36.4 0.1 1.1e-07 31.8 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EMD00005.1 - 1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 EMD00005.1 - 7.3e-05 22.6 0.0 8.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 EMD00005.1 - 0.00044 20.1 0.0 0.00057 19.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMD00005.1 - 0.00077 20.1 0.0 0.0016 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EMD00005.1 - 0.001 18.7 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_18 PF12847.7 EMD00005.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMD00005.1 - 0.023 15.3 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EMD00005.1 - 0.047 13.2 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EMD00005.1 - 0.091 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 EMD00005.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase BTB PF00651.31 EMD00006.1 - 3.4e-07 30.5 0.0 5.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain IBR PF01485.21 EMD00006.1 - 0.021 15.0 4.9 0.021 15.0 4.9 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain KH_1 PF00013.29 EMD00007.1 - 2.9e-41 139.1 5.1 1.6e-18 66.3 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EMD00007.1 - 1.7e-10 40.6 4.0 0.0035 17.1 0.2 3.2 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EMD00007.1 - 7.7e-05 22.6 0.0 0.019 14.9 0.0 2.3 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_5 PF13184.6 EMD00007.1 - 0.00026 21.0 7.1 0.24 11.5 0.2 3.5 3 1 0 3 3 3 2 NusA-like KH domain KH_4 PF13083.6 EMD00007.1 - 0.00036 20.3 1.1 1.4 8.9 0.1 3.3 3 0 0 3 3 3 1 KH domain DUF2013 PF09431.10 EMD00010.1 - 7.2e-53 178.5 0.1 1.9e-52 177.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) WAPL PF07814.13 EMD00010.1 - 0.0053 15.6 1.2 0.26 10.0 1.0 2.5 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin NopRA1 PF16201.5 EMD00010.1 - 0.043 13.4 0.3 0.12 12.0 0.1 1.8 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 MFS_1 PF07690.16 EMD00011.1 - 8e-17 61.2 36.0 8e-17 61.2 36.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4389 PF14333.6 EMD00011.1 - 3.6 7.6 6.2 0.86 9.6 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) MFS_1 PF07690.16 EMD00013.1 - 6.4e-31 107.6 18.7 6.4e-31 107.6 18.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_S10 PF00338.22 EMD00014.1 - 1e-26 93.0 0.3 1.3e-26 92.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.16 EMD00015.1 - 1e-07 31.5 0.0 3.6e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 CUE domain FXMRP1_C_core PF12235.8 EMD00015.1 - 0.51 11.0 11.9 1.5 9.4 11.9 1.8 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal MAM33 PF02330.16 EMD00016.1 - 3.2e-54 184.1 5.2 1.2e-53 182.3 5.2 1.7 1 1 0 1 1 1 1 Mitochondrial glycoprotein Dfp1_Him1_M PF08630.10 EMD00016.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Dfp1/Him1, central region CdiI_2 PF18593.1 EMD00016.1 - 0.13 13.0 0.6 25 5.6 0.2 2.6 2 1 0 2 2 2 0 CdiI immunity protein DnaJ PF00226.31 EMD00017.1 - 1.7e-07 31.2 0.0 3.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3450 PF11932.8 EMD00017.1 - 0.081 12.2 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Mito_carr PF00153.27 EMD00018.1 - 4.8e-52 173.9 2.8 1.1e-20 73.4 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Tim17 PF02466.19 EMD00018.1 - 0.29 11.5 3.8 9.4 6.7 0.0 3.6 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family MFS_1 PF07690.16 EMD00019.1 - 2.5e-28 99.1 24.9 4.5e-28 98.2 24.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 EMD00019.1 - 0.05 13.8 0.5 0.05 13.8 0.5 4.1 5 1 1 6 6 6 0 Protein of unknown function (DUF2530) MASE4 PF17158.4 EMD00019.1 - 0.25 10.6 6.4 0.13 11.5 0.4 2.7 3 0 0 3 3 3 0 Membrane-associated sensor, integral membrane domain Mon1 PF03164.14 EMD00023.1 - 1.7e-151 504.9 0.0 1.9e-151 504.8 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 CH PF00307.31 EMD00024.1 - 0.00028 21.0 0.0 0.00086 19.5 0.0 1.8 1 1 0 1 1 1 1 Calponin homology (CH) domain Lactamase_B_3 PF13483.6 EMD00025.1 - 1.4e-06 28.3 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EMD00025.1 - 0.012 15.2 0.2 0.028 14.0 0.1 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Pyridoxal_deC PF00282.19 EMD00026.1 - 1e-25 90.3 0.0 2.3e-25 89.1 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EMD00026.1 - 0.00046 19.5 0.0 0.00075 18.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 EMD00026.1 - 0.0026 16.5 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_5 PF00266.19 EMD00026.1 - 0.0038 16.2 0.0 0.012 14.7 0.0 1.8 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EMD00026.1 - 0.0067 15.8 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2370 PF10176.9 EMD00027.1 - 1.5e-87 293.0 0.2 3.7e-87 291.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 EMD00027.1 - 0.034 14.2 0.0 0.097 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) N6-adenineMlase PF10237.9 EMD00028.1 - 6.9e-55 185.2 0.0 1.2e-54 184.5 0.0 1.3 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase MTS PF05175.14 EMD00028.1 - 0.078 12.5 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Pkinase PF00069.25 EMD00029.1 - 1.3e-70 237.7 0.0 1.7e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD00029.1 - 7.5e-29 100.8 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMD00029.1 - 1.5e-07 31.0 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMD00029.1 - 0.00012 21.0 0.1 0.00027 19.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EMD00029.1 - 0.00022 20.6 0.1 0.001 18.4 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMD00029.1 - 0.00042 20.3 0.2 0.00075 19.5 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Thi4 PF01946.17 EMD00030.1 - 2.1e-112 374.0 0.1 2.5e-112 373.8 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EMD00030.1 - 9.4e-07 28.7 1.4 1.2e-05 25.1 0.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMD00030.1 - 0.00051 20.2 1.3 0.0015 18.7 1.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EMD00030.1 - 0.0013 17.9 1.2 0.0025 16.9 1.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EMD00030.1 - 0.0033 16.7 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EMD00030.1 - 0.0089 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EMD00030.1 - 0.02 14.0 5.0 0.14 11.2 1.3 2.7 2 1 1 3 3 3 0 FAD binding domain NAD_binding_9 PF13454.6 EMD00030.1 - 0.035 14.1 0.6 0.065 13.2 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EMD00030.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EMD00030.1 - 0.14 11.3 1.1 0.23 10.7 1.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EMD00030.1 - 0.2 10.3 0.7 0.65 8.6 1.0 1.6 2 0 0 2 2 2 0 HI0933-like protein DUF2183 PF09949.9 EMD00033.1 - 3e-33 114.1 0.0 5.4e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) RRM_1 PF00076.22 EMD00036.1 - 2.3e-10 40.2 0.0 3.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 EMD00038.1 - 3e-23 82.5 0.1 1.8e-22 80.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 EMD00038.1 - 1e-21 76.8 0.1 3.2e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.31 EMD00038.1 - 3.7e-21 75.6 0.4 3.9e-19 69.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EMD00038.1 - 1.2e-17 64.3 9.3 1.2e-17 64.3 9.3 2.1 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 EMD00038.1 - 2.6e-08 34.0 0.0 7.3e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EMD00038.1 - 0.066 12.5 0.8 0.14 11.4 0.1 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain SNF2_N PF00176.23 EMD00038.1 - 0.089 11.5 0.1 0.19 10.4 0.0 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 EMD00038.1 - 0.38 11.0 2.2 4.2 7.6 0.3 3.3 3 1 0 3 3 3 0 AAA domain DNA_pol3_delta2 PF13177.6 EMD00038.1 - 6.1 6.6 8.2 5.5 6.7 1.1 3.3 1 1 2 3 3 3 0 DNA polymerase III, delta subunit Thioredoxin PF00085.20 EMD00039.1 - 5.1e-66 219.1 1.8 1.5e-31 108.5 0.0 4.4 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EMD00039.1 - 1e-46 159.2 0.0 4.5e-35 121.2 0.1 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 EMD00039.1 - 2.1e-12 46.8 0.2 3.9e-12 45.9 0.2 1.4 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_8 PF13905.6 EMD00039.1 - 6.9e-09 35.9 0.1 0.015 15.6 0.0 4.3 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EMD00039.1 - 1.2e-07 32.2 0.5 0.0028 18.1 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EMD00039.1 - 1.4e-07 31.6 0.2 0.0019 18.4 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 EMD00039.1 - 3.9e-07 29.7 0.1 0.22 10.9 0.0 3.4 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EMD00039.1 - 4.1e-06 26.7 0.2 0.079 12.9 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 EMD00039.1 - 0.0027 17.5 2.4 2.5 7.8 0.0 3.9 4 0 0 4 4 4 2 Redoxin Pdase_C33_assoc PF14756.6 EMD00039.1 - 0.046 13.7 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C33-associated domain APH PF01636.23 EMD00040.1 - 2.2e-10 40.9 0.1 5e-10 39.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family THUMP PF02926.17 EMD00041.1 - 1.3e-10 41.5 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 THUMP domain ASF1_hist_chap PF04729.13 EMD00042.1 - 9.8e-73 243.2 0.0 1.3e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0172 PF03665.13 EMD00042.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Plasmodium_Vir PF05795.11 EMD00042.1 - 0.88 8.9 3.5 1.2 8.5 3.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CSN8_PSD8_EIF3K PF10075.9 EMD00044.1 - 3.5e-35 121.1 0.0 5.1e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Sec34 PF04136.15 EMD00045.1 - 7.9e-49 165.4 1.4 1.7e-48 164.3 1.4 1.6 1 0 0 1 1 1 1 Sec34-like family Phasin_2 PF09361.10 EMD00045.1 - 0.017 15.4 4.0 2.4 8.5 0.4 3.1 2 0 0 2 2 2 0 Phasin protein Gpi1 PF05024.15 EMD00046.1 - 9e-77 257.4 8.6 9e-77 257.4 8.6 1.8 3 0 0 3 3 3 1 N-acetylglucosaminyl transferase component (Gpi1) DUF3142 PF11340.8 EMD00046.1 - 0.023 14.5 0.3 0.12 12.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) Nucleoporin_FG PF13634.6 EMD00048.1 - 0.031 15.1 90.1 15 6.6 15.4 4.8 1 1 2 3 3 3 0 Nucleoporin FG repeat region COG5 PF10392.9 EMD00049.1 - 3e-32 111.6 3.0 3e-32 111.6 3.0 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF948 PF06103.11 EMD00049.1 - 0.055 13.7 0.6 0.38 11.0 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4667 PF15700.5 EMD00049.1 - 0.14 12.3 0.1 0.14 12.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Dopey_N PF04118.14 EMD00050.1 - 2.1e-104 348.9 0.0 1.2e-103 346.4 0.0 2.1 2 0 0 2 2 2 1 Dopey, N-terminal DUF3361 PF11841.8 EMD00050.1 - 0.14 12.1 1.5 3.3 7.6 1.5 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) Aldose_epim PF01263.20 EMD00051.1 - 2e-59 201.4 0.0 2.5e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.18 EMD00052.1 - 6.4e-09 35.8 13.2 1.3e-08 34.8 13.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.28 EMD00056.1 - 1.8e-88 297.3 0.4 2e-88 297.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HopW1-1 PF15457.6 EMD00056.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Phage_r1t_holin PF16945.5 EMD00056.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin PKD_channel PF08016.12 EMD00057.1 - 0.04 12.6 7.2 0.65 8.6 0.5 2.3 2 0 0 2 2 2 0 Polycystin cation channel EMG1 PF03587.14 EMD00058.1 - 7.4e-79 263.9 0.0 8.6e-79 263.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase F-box-like_2 PF13013.6 EMD00060.1 - 0.11 12.5 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 F-box-like domain PhyH PF05721.13 EMD00061.1 - 4.6e-16 59.7 0.1 5.5e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Lyase_aromatic PF00221.19 EMD00062.1 - 8.9e-149 496.1 10.5 1.1e-148 495.8 10.5 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase zf-RING_2 PF13639.6 EMD00063.1 - 2.3e-09 37.5 5.2 2.3e-09 37.5 5.2 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EMD00063.1 - 1.2e-07 31.4 3.0 1.8e-07 30.9 3.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EMD00063.1 - 1.7e-06 27.8 3.4 2.5e-06 27.2 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EMD00063.1 - 3.6e-06 27.2 2.2 3.6e-06 27.2 2.2 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EMD00063.1 - 3.4e-05 23.6 5.0 5.6e-05 22.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMD00063.1 - 0.00052 19.8 3.3 0.00082 19.2 3.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EMD00063.1 - 0.032 14.3 3.1 0.033 14.2 1.6 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 EMD00063.1 - 0.046 13.7 2.4 0.08 12.9 2.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 EMD00063.1 - 0.06 13.1 1.8 0.06 13.1 1.8 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EMD00063.1 - 0.08 13.0 2.1 0.99 9.5 1.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HIT PF01230.23 EMD00064.1 - 5.4e-23 81.6 0.4 7.4e-23 81.1 0.4 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EMD00064.1 - 1.5e-14 54.5 0.1 2.1e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EMD00064.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF1275 PF06912.11 EMD00065.1 - 1.1e-43 149.4 19.1 1.3e-43 149.1 19.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Cupin_1 PF00190.22 EMD00066.1 - 7.2e-42 142.5 0.0 5.1e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EMD00066.1 - 2.5e-24 84.8 1.1 1.3e-11 44.1 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EMD00066.1 - 1.8e-10 40.3 0.0 0.00085 19.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EMD00066.1 - 3.8e-07 30.1 0.9 0.00079 19.3 0.1 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 EMD00066.1 - 0.0014 18.8 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 Mif2/CENP-C like MannoseP_isomer PF01050.18 EMD00066.1 - 0.005 16.7 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.14 EMD00066.1 - 0.13 12.4 0.1 17 5.6 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family BiPBP_C PF06832.12 EMD00066.1 - 0.14 12.2 0.1 19 5.4 0.1 2.7 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Abhydrolase_1 PF00561.20 EMD00067.1 - 1.7e-22 80.3 0.0 1.9e-17 63.8 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMD00067.1 - 8.8e-19 67.7 0.0 1.6e-18 66.9 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMD00067.1 - 1.4e-16 61.8 0.0 1.8e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EMD00067.1 - 2.2e-10 39.7 0.0 3.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 EMD00067.1 - 6.8e-06 25.7 0.0 0.019 14.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 EMD00067.1 - 2.7e-05 24.0 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EMD00067.1 - 0.0002 21.4 0.0 0.0005 20.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 EMD00067.1 - 0.00072 19.3 0.0 0.00097 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EMD00067.1 - 0.0022 18.2 0.0 0.0022 18.1 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain DLH PF01738.18 EMD00067.1 - 0.0022 17.6 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EMD00067.1 - 0.005 16.8 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EMD00067.1 - 0.01 15.7 0.0 5 6.9 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 EMD00067.1 - 0.014 14.3 0.3 0.042 12.8 0.3 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.9 EMD00067.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 EMD00067.1 - 0.069 13.0 0.1 0.09 12.6 0.2 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EMD00067.1 - 0.08 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 EMD00067.1 - 0.18 11.5 0.1 0.61 9.8 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DUF915 PF06028.11 EMD00067.1 - 0.24 10.7 0.0 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Seryl_tRNA_N PF02403.22 EMD00068.1 - 0.0033 17.6 0.8 1.6 9.0 0.3 2.6 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 EMD00068.1 - 0.018 14.4 5.0 0.72 9.2 1.8 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3829 PF12889.7 EMD00068.1 - 0.021 14.3 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) JIP_LZII PF16471.5 EMD00068.1 - 0.66 10.2 8.3 0.15 12.2 0.4 2.9 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II Takusan PF04822.13 EMD00068.1 - 6.5 6.7 14.8 4.5 7.2 0.1 3.7 3 1 0 4 4 4 0 Takusan TPR_19 PF14559.6 EMD00069.1 - 2.8e-10 40.5 5.0 2.3e-06 28.0 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMD00069.1 - 1.3e-07 31.1 14.3 0.11 12.7 0.1 7.7 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMD00069.1 - 3.9e-07 29.8 4.3 0.16 12.2 0.0 6.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMD00069.1 - 1.7e-05 24.4 7.0 19 5.3 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EMD00069.1 - 2.9e-05 24.6 0.1 2.9e-05 24.6 0.1 5.4 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMD00069.1 - 7.5e-05 23.2 17.2 0.025 15.4 0.3 7.5 7 1 1 8 8 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMD00069.1 - 0.00017 21.6 0.3 0.096 12.8 0.0 4.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 EMD00069.1 - 0.00045 19.9 2.4 0.0058 16.3 0.1 3.3 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 EMD00069.1 - 0.0033 17.9 3.1 1.3 9.8 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMD00069.1 - 0.023 14.9 0.8 0.39 11.0 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EMD00069.1 - 0.057 14.1 0.1 0.057 14.1 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMD00069.1 - 0.057 13.5 13.7 2 8.6 0.1 7.1 9 0 0 9 9 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EMD00069.1 - 0.1 13.1 0.1 7.2 7.1 0.1 2.9 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_17 PF13431.6 EMD00069.1 - 0.35 11.4 5.0 0.89 10.1 0.0 4.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMD00069.1 - 0.36 11.1 12.6 5.1 7.5 0.0 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat BTAD PF03704.17 EMD00069.1 - 1.2 9.5 7.0 0.29 11.6 0.1 3.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 EMD00069.1 - 1.7 9.0 10.1 1.6 9.2 0.0 5.3 6 1 1 7 7 6 0 Tetratricopeptide repeat Oxysterol_BP PF01237.18 EMD00070.1 - 1.2e-53 182.3 3.5 1.1e-51 175.9 3.5 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein COX6B PF02297.17 EMD00071.1 - 3.1e-23 81.8 3.8 3.8e-23 81.5 3.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 EMD00071.1 - 0.063 13.3 4.9 0.067 13.2 1.8 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EMD00071.1 - 0.3 11.4 2.9 1.7 9.0 3.0 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 ARID PF01388.21 EMD00072.1 - 5.1e-16 59.1 0.0 1.5e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Img2 PF05046.14 EMD00075.1 - 3.3e-24 85.0 0.0 4.5e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Peptidase_C2 PF00648.21 EMD00076.1 - 6.8e-30 104.1 0.0 2e-29 102.6 0.0 1.7 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EMD00076.1 - 1.5e-08 35.0 0.0 4.5e-07 30.2 0.0 2.7 1 1 0 1 1 1 1 Calpain large subunit, domain III NRBF2_MIT PF17169.4 EMD00076.1 - 0.038 14.2 1.5 0.11 12.7 1.5 1.8 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Mito_carr PF00153.27 EMD00077.1 - 3.9e-54 180.6 0.2 8.4e-19 67.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UDG PF03167.19 EMD00078.1 - 1.5e-22 80.2 0.1 3.3e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Aldo_ket_red PF00248.21 EMD00079.1 - 5.8e-75 252.2 0.0 7.2e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pyrid_ox_like PF16242.5 EMD00080.1 - 1.2e-22 80.0 0.0 2.3e-22 79.2 0.0 1.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EMD00080.1 - 3.4e-06 27.2 0.0 6.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PHBC_N PF12551.8 EMD00080.1 - 0.1 12.4 0.8 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal ADH_zinc_N_2 PF13602.6 EMD00081.1 - 3e-13 51.0 0.0 4.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMD00081.1 - 9.6e-10 38.5 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMD00081.1 - 1.2e-08 34.8 0.0 2.6e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Hydrolase_6 PF13344.6 EMD00081.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Glyco_hydro_11 PF00457.17 EMD00082.1 - 3.4e-52 176.6 17.8 4.3e-52 176.3 17.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Pyocin_S PF06958.12 EMD00083.1 - 0.026 15.1 0.3 0.047 14.2 0.3 1.4 1 0 0 1 1 1 0 S-type Pyocin Sugar_tr PF00083.24 EMD00084.1 - 1e-85 288.3 16.1 1.2e-85 288.1 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMD00084.1 - 1.3e-36 126.3 11.1 1.3e-36 126.3 11.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EMD00084.1 - 7.7e-06 24.6 0.6 7.7e-06 24.6 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EMD00084.1 - 0.0023 17.3 2.0 0.0023 17.3 2.0 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EMD00084.1 - 0.018 13.4 9.8 1.1 7.4 1.2 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EMD00084.1 - 0.026 12.9 6.7 0.069 11.5 0.3 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector Mrx7 PF10906.8 EMD00085.1 - 9e-06 25.9 0.0 3.4e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 MIOREX complex component 7 Y_phosphatase PF00102.27 EMD00086.1 - 1.4e-49 168.8 0.0 2.3e-49 168.1 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EMD00086.1 - 0.002 17.9 0.2 0.0076 16.1 0.2 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Chromo PF00385.24 EMD00087.1 - 0.00064 19.6 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2828 PF11443.8 EMD00088.1 - 8.1e-241 800.5 0.0 1e-183 611.9 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) Cpn10 PF00166.21 EMD00088.1 - 0.12 12.4 0.0 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Med14 PF08638.11 EMD00089.1 - 3.2e-57 193.0 0.0 5.4e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 Prefoldin PF02996.17 EMD00090.1 - 1.8e-31 108.5 0.2 3.8e-31 107.5 0.1 1.5 1 1 1 2 2 2 1 Prefoldin subunit APG17 PF04108.12 EMD00090.1 - 0.0042 16.3 0.6 0.011 14.9 0.1 1.7 2 0 0 2 2 2 1 Autophagy protein Apg17 Prefoldin_2 PF01920.20 EMD00090.1 - 0.011 15.7 1.2 0.065 13.2 0.1 2.2 2 1 0 2 2 2 0 Prefoldin subunit Filament PF00038.21 EMD00090.1 - 0.03 13.9 0.2 6 6.4 0.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein Cpn60_TCP1 PF00118.24 EMD00091.1 - 1.5e-162 541.7 0.1 1.7e-162 541.5 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 EMD00091.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Nop PF01798.18 EMD00092.1 - 2.5e-85 285.6 0.0 5e-85 284.6 0.0 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EMD00092.1 - 2.4e-17 63.1 0.0 2.4e-17 63.1 0.0 2.6 3 0 0 3 3 3 1 NOP5NT (NUC127) domain WW PF00397.26 EMD00093.1 - 0.015 15.4 0.4 0.015 15.4 0.4 2.0 2 0 0 2 2 2 0 WW domain CDC45 PF02724.14 EMD00093.1 - 0.22 9.8 9.1 0.28 9.5 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein NAM-associated PF14303.6 EMD00093.1 - 2.3 8.9 9.4 3 8.6 9.4 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain zf-RING_2 PF13639.6 EMD00094.1 - 1.2e-07 31.9 6.9 1.2e-07 31.9 6.9 2.1 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 EMD00094.1 - 0.00096 19.3 5.0 0.00096 19.3 5.0 1.8 2 0 0 2 2 2 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EMD00094.1 - 0.0052 16.8 2.8 0.0052 16.8 2.8 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EMD00094.1 - 0.018 15.3 5.4 0.018 15.3 5.4 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain PHD PF00628.29 EMD00094.1 - 0.025 14.5 7.0 0.056 13.3 7.0 1.6 1 0 0 1 1 1 0 PHD-finger V_ATPase_prox PF18274.1 EMD00094.1 - 0.14 12.1 0.8 0.29 11.1 0.8 1.5 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe MRP-S25 PF13741.6 EMD00094.1 - 0.23 11.0 1.4 1.6 8.2 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S25 zf-C3HC4_3 PF13920.6 EMD00094.1 - 0.3 11.0 5.3 0.77 9.7 5.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nucleo_P87 PF07267.11 EMD00094.1 - 0.37 9.6 1.4 0.49 9.2 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Zn_ribbon_17 PF17120.5 EMD00094.1 - 1.5 8.5 8.4 0.57 9.9 5.4 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EMD00094.1 - 2.3 8.4 6.8 5.1 7.3 6.8 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 EMD00094.1 - 5.2 7.1 18.0 0.31 11.0 5.9 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Exo_endo_phos PF03372.23 EMD00095.1 - 3.4e-19 69.3 0.1 1.4e-18 67.3 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EMD00095.1 - 1.2e-12 47.8 2.0 5.7e-07 29.7 0.2 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMD00095.1 - 1.2e-12 47.4 4.5 4.3e-08 32.8 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat Phage_fiber PF03335.13 EMD00095.1 - 0.19 11.9 2.6 0.6 10.4 2.6 1.9 1 0 0 1 1 1 0 Phage tail fibre repeat LRR_6 PF13516.6 EMD00095.1 - 0.39 10.9 2.2 0.73 10.0 0.0 2.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EMD00095.1 - 0.99 10.2 6.8 8.7 7.3 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat LSM PF01423.22 EMD00097.1 - 6.5e-16 57.8 0.0 8.4e-16 57.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EMD00097.1 - 0.0055 16.8 0.0 0.0073 16.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkr1 PF08636.10 EMD00098.1 - 1.1e-30 105.6 5.9 1.4e-30 105.2 5.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 SnoaL PF07366.12 EMD00099.1 - 0.00019 21.2 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EMD00099.1 - 0.0015 19.1 0.0 0.0034 18.0 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain DAPDH_C PF16654.5 EMD00100.1 - 0.24 11.2 3.0 0.31 10.9 1.0 2.1 2 0 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain TraY PF05509.11 EMD00100.1 - 0.31 11.1 4.0 8.8 6.4 2.5 2.5 2 0 0 2 2 2 0 TraY domain DUF3584 PF12128.8 EMD00100.1 - 1.1 6.6 29.4 1.9 5.9 29.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1741 PF08427.10 EMD00100.1 - 2.2 7.9 5.2 0.23 11.1 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) Golgin_A5 PF09787.9 EMD00100.1 - 9.4 5.6 28.3 16 4.8 27.0 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 4HBT_2 PF13279.6 EMD00101.1 - 6.5e-28 97.7 0.0 9.4e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EMD00101.1 - 0.0037 17.6 0.0 0.0062 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Complex1_LYR_2 PF13233.6 EMD00102.1 - 0.00048 20.8 0.1 0.00058 20.5 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EMD00102.1 - 0.0093 16.0 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3135 PF11333.8 EMD00102.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Methyltransf_25 PF13649.6 EMD00103.1 - 2.3e-11 44.3 0.0 4.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMD00103.1 - 1.4e-08 35.2 0.0 2.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMD00103.1 - 4.1e-07 29.9 0.0 7.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMD00103.1 - 2.1e-06 27.7 0.0 3.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMD00103.1 - 0.00045 20.9 0.0 0.00081 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EMD00103.1 - 0.051 13.4 0.0 0.16 11.8 0.0 1.8 2 1 0 2 2 2 0 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EMD00103.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HA2 PF04408.23 EMD00104.1 - 1.4e-21 76.8 0.3 2.9e-21 75.8 0.2 1.6 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EMD00104.1 - 1.1e-13 51.3 0.0 2.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EMD00104.1 - 2e-13 50.6 0.0 3.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WLM PF08325.10 EMD00105.1 - 3.5e-26 92.4 0.7 9.6e-26 91.0 0.7 1.8 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 EMD00105.1 - 8.3e-07 29.3 0.8 2e-06 28.0 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 EMD00105.1 - 0.01 15.1 1.3 0.01 15.1 1.3 2.5 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Abhydrolase_1 PF00561.20 EMD00106.1 - 4.1e-11 43.0 0.1 1.1e-10 41.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMD00106.1 - 5.2e-08 32.5 0.0 1.7e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EMD00106.1 - 0.0054 16.2 0.0 0.017 14.6 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EMD00106.1 - 0.0094 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S10 PF00450.22 EMD00106.1 - 0.076 12.4 0.1 8.2 5.7 0.1 2.3 2 0 0 2 2 2 0 Serine carboxypeptidase DUF4110 PF13422.6 EMD00107.1 - 1.3e-29 102.1 3.2 1.3e-29 102.1 3.2 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 EMD00107.1 - 8.6e-29 99.2 7.3 1.4e-09 38.0 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EMD00107.1 - 4.5e-27 93.8 8.4 2.7e-10 40.1 0.1 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EMD00107.1 - 2e-18 66.0 10.1 0.00081 19.3 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EMD00107.1 - 1.1e-17 63.6 6.4 2.7e-05 24.3 0.2 5.7 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EMD00107.1 - 6.4e-12 44.9 5.3 0.031 14.3 0.0 6.0 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EMD00107.1 - 5e-07 29.2 6.6 0.88 9.2 0.1 5.6 5 1 0 5 5 5 3 Kelch motif MCPVI PF02993.14 EMD00107.1 - 0.34 10.7 1.8 0.77 9.5 1.8 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Prefoldin_2 PF01920.20 EMD00108.1 - 4.9e-23 81.1 12.3 6.2e-23 80.8 12.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EMD00108.1 - 0.00012 22.1 4.5 0.00012 22.0 4.0 1.3 1 1 0 1 1 1 1 Prefoldin subunit MIP-T3_C PF17749.1 EMD00108.1 - 0.0043 17.0 2.6 0.0043 17.0 2.6 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Rootletin PF15035.6 EMD00108.1 - 0.007 16.4 2.4 0.007 16.4 2.4 1.4 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Spc24 PF08286.11 EMD00108.1 - 0.012 15.8 10.8 0.055 13.7 3.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.17 EMD00108.1 - 0.016 15.1 12.9 3.4 7.6 12.9 2.5 1 1 0 1 1 1 0 Prefoldin subunit DUF3160 PF11369.8 EMD00108.1 - 0.044 12.2 3.7 0.049 12.1 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) Uso1_p115_C PF04871.13 EMD00108.1 - 0.068 13.6 13.5 0.18 12.2 6.4 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 EMD00108.1 - 0.074 13.3 11.1 0.071 13.3 3.3 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PH_11 PF15413.6 EMD00108.1 - 0.079 13.4 0.1 3.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Spc7 PF08317.11 EMD00108.1 - 0.1 11.5 12.7 0.14 11.0 12.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DASH_Dam1 PF08653.10 EMD00108.1 - 0.1 12.4 1.4 0.31 10.9 0.2 2.2 3 0 0 3 3 2 0 DASH complex subunit Dam1 Jnk-SapK_ap_N PF09744.9 EMD00108.1 - 0.13 12.5 9.0 0.17 12.1 9.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ERM PF00769.19 EMD00108.1 - 0.13 12.1 10.7 0.16 11.7 10.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Rx_N PF18052.1 EMD00108.1 - 0.14 12.5 6.2 1 9.7 1.4 2.2 1 1 1 2 2 2 0 Rx N-terminal domain DUF5446 PF17522.2 EMD00108.1 - 0.15 12.3 1.9 0.27 11.4 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) STAT_alpha PF01017.20 EMD00108.1 - 0.15 11.9 8.6 0.63 9.9 2.3 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain Osmo_CC PF08946.10 EMD00108.1 - 0.17 12.1 6.6 0.085 13.1 2.6 2.4 2 1 0 2 2 2 0 Osmosensory transporter coiled coil CENP-F_leu_zip PF10473.9 EMD00108.1 - 0.18 11.8 12.9 0.5 10.4 4.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec34 PF04136.15 EMD00108.1 - 0.18 11.7 7.6 1.9 8.3 3.2 2.1 1 1 1 2 2 2 0 Sec34-like family TPR_MLP1_2 PF07926.12 EMD00108.1 - 0.18 11.9 13.1 3.3 7.8 6.9 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DegS PF05384.11 EMD00108.1 - 0.2 11.2 9.1 0.66 9.5 2.2 2.2 2 0 0 2 2 2 0 Sensor protein DegS ATG_C PF09333.11 EMD00108.1 - 0.2 12.0 2.6 0.51 10.7 0.7 2.1 1 1 1 2 2 2 0 Autophagy-related protein C terminal domain PHM7_cyt PF14703.6 EMD00108.1 - 0.2 11.9 5.3 0.36 11.1 5.3 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Macoilin PF09726.9 EMD00108.1 - 0.21 10.1 9.3 0.28 9.7 9.3 1.1 1 0 0 1 1 1 0 Macoilin family ERp29 PF07749.12 EMD00108.1 - 0.24 12.3 5.0 0.6 11.0 5.0 1.7 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Golgin_A5 PF09787.9 EMD00108.1 - 0.25 10.8 10.5 0.25 10.8 9.6 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 Fzo_mitofusin PF04799.13 EMD00108.1 - 0.31 10.6 7.6 3.3 7.2 0.3 2.1 2 0 0 2 2 2 0 fzo-like conserved region GAS PF13851.6 EMD00108.1 - 0.32 10.3 13.1 6.4 6.1 13.1 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2312 PF10073.9 EMD00108.1 - 0.35 10.5 6.3 0.66 9.7 0.9 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) NPV_P10 PF05531.12 EMD00108.1 - 0.39 11.2 6.2 3.6 8.1 1.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cep57_CLD_2 PF14197.6 EMD00108.1 - 0.41 10.8 5.7 0.2 11.8 2.3 2.3 2 1 1 3 3 2 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 EMD00108.1 - 0.43 11.1 14.4 4.7 7.8 7.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region JIP_LZII PF16471.5 EMD00108.1 - 0.48 10.6 7.8 0.52 10.5 1.4 2.8 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Fib_alpha PF08702.10 EMD00108.1 - 0.56 10.4 11.0 2.1 8.5 11.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 EMD00108.1 - 0.6 10.9 7.0 0.44 11.3 1.7 2.1 1 1 0 2 2 2 0 Occludin homology domain Tup_N PF08581.10 EMD00108.1 - 0.61 10.4 10.1 6.7 7.1 0.3 3.1 2 1 1 3 3 3 0 Tup N-terminal YabA PF06156.13 EMD00108.1 - 0.61 10.8 6.3 0.79 10.4 1.1 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF5082 PF16888.5 EMD00108.1 - 0.66 10.3 12.8 2.5 8.4 12.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) XhlA PF10779.9 EMD00108.1 - 0.83 9.9 6.1 0.17 12.1 0.8 2.2 2 1 0 2 2 2 0 Haemolysin XhlA DHR10 PF18595.1 EMD00108.1 - 1.2 9.2 12.8 7.5 6.6 12.8 2.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain ATG16 PF08614.11 EMD00108.1 - 1.3 9.2 12.3 1.7 8.8 3.8 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Muted PF14942.6 EMD00108.1 - 1.4 9.2 11.1 0.4 11.0 1.0 2.1 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Bcr-Abl_Oligo PF09036.10 EMD00108.1 - 1.5 8.9 5.3 3.3 7.8 0.4 2.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF4407 PF14362.6 EMD00108.1 - 1.6 8.0 7.6 2 7.7 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 EMD00108.1 - 1.9 8.0 13.3 1.4 8.4 8.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 BRE1 PF08647.11 EMD00108.1 - 2.2 8.4 11.9 6.4 6.9 0.6 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 EMD00108.1 - 2.3 8.3 10.6 3.2 7.8 1.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 EMD00108.1 - 3.3 7.8 14.9 5.8 7.0 14.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 EMD00108.1 - 3.8 8.0 11.4 7.2 7.1 2.2 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 EMD00108.1 - 3.9 6.6 8.4 1.4 8.1 3.9 1.7 1 1 1 2 2 2 0 TMPIT-like protein ABC_tran_CTD PF16326.5 EMD00108.1 - 4.9 7.5 15.3 6.7 7.0 0.6 3.8 2 2 0 2 2 2 0 ABC transporter C-terminal domain Csm1_N PF18504.1 EMD00108.1 - 5.2 7.5 14.7 8.5 6.8 2.2 3.3 2 2 1 3 3 3 0 Csm1 N-terminal domain YlqD PF11068.8 EMD00108.1 - 5.2 7.5 16.8 3 8.2 2.3 2.1 2 0 0 2 2 2 0 YlqD protein FliD_N PF02465.18 EMD00108.1 - 8.8 7.1 13.2 3.9 8.2 5.5 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AAA PF00004.29 EMD00109.1 - 2.3e-42 144.6 0.0 4.1e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EMD00109.1 - 3.5e-30 103.8 0.1 1.1e-29 102.2 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EMD00109.1 - 1.5e-22 79.4 6.5 3.4e-22 78.3 6.5 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 EMD00109.1 - 5.1e-06 26.3 0.0 9.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EMD00109.1 - 9.3e-06 25.4 0.0 3.8e-05 23.4 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EMD00109.1 - 1.4e-05 25.6 0.1 0.00014 22.3 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EMD00109.1 - 1.8e-05 24.9 0.1 0.0045 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EMD00109.1 - 2.9e-05 24.1 0.0 0.00013 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EMD00109.1 - 6.1e-05 22.8 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EMD00109.1 - 7.7e-05 23.0 0.0 0.01 16.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 EMD00109.1 - 7.8e-05 22.0 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EMD00109.1 - 0.00013 22.3 0.1 0.0054 17.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EMD00109.1 - 0.00013 22.0 0.0 0.00034 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EMD00109.1 - 0.00062 20.3 0.3 0.0017 18.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 EMD00109.1 - 0.00069 18.9 0.0 0.0019 17.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EMD00109.1 - 0.0015 18.7 0.0 0.0043 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EMD00109.1 - 0.0018 18.0 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EMD00109.1 - 0.0039 17.6 0.1 0.035 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain USP8_dimer PF08969.11 EMD00109.1 - 0.012 15.7 5.5 0.025 14.8 5.5 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain Phage_GPO PF05929.11 EMD00109.1 - 0.013 15.1 0.6 0.024 14.3 0.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_25 PF13481.6 EMD00109.1 - 0.019 14.6 0.1 0.66 9.5 0.1 2.5 1 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EMD00109.1 - 0.021 14.4 0.1 0.11 12.0 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EMD00109.1 - 0.026 13.9 0.0 0.081 12.3 0.0 1.8 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 EMD00109.1 - 0.039 14.0 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Torsin Zeta_toxin PF06414.12 EMD00109.1 - 0.041 13.2 0.1 1.5 8.0 0.1 2.9 2 1 1 3 3 3 0 Zeta toxin Parvo_NS1 PF01057.17 EMD00109.1 - 0.057 12.5 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EMD00109.1 - 0.064 13.2 0.0 0.69 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 EMD00109.1 - 0.067 12.6 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Cytidylate_kin PF02224.18 EMD00109.1 - 0.079 12.7 1.1 0.51 10.0 0.0 2.6 2 1 1 3 3 3 0 Cytidylate kinase KAP_NTPase PF07693.14 EMD00109.1 - 0.079 12.2 1.7 13 4.9 0.2 2.9 2 1 1 3 3 3 0 KAP family P-loop domain ATPase PF06745.13 EMD00109.1 - 0.14 11.5 0.0 8.9 5.6 0.0 2.4 1 1 1 2 2 2 0 KaiC CPT PF07931.12 EMD00109.1 - 0.16 11.8 0.0 0.52 10.1 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ATPase_2 PF01637.18 EMD00109.1 - 0.4 10.5 2.3 1.2 8.9 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 EMD00110.1 - 6.3e-77 257.9 0.0 1e-76 257.2 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EMD00110.1 - 1.7e-25 89.6 0.0 5e-25 88.1 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EMD00110.1 - 1e-11 45.3 0.1 4e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EMD00110.1 - 4e-07 30.1 3.1 4e-07 30.1 3.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain Myosin_tail_1 PF01576.19 EMD00110.1 - 8.4e-06 23.9 102.7 1.8e-05 22.8 44.4 3.9 2 2 2 4 4 4 3 Myosin tail FlxA PF14282.6 EMD00110.1 - 0.00011 22.1 4.5 0.00011 22.1 4.5 6.2 3 2 2 6 6 6 2 FlxA-like protein AAA_29 PF13555.6 EMD00110.1 - 0.00053 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2968 PF11180.8 EMD00110.1 - 0.00077 19.1 4.7 0.00077 19.1 4.7 6.3 4 2 4 8 8 8 1 Protein of unknown function (DUF2968) KASH_CCD PF14662.6 EMD00110.1 - 0.0033 17.3 9.4 0.0033 17.3 9.4 6.4 4 2 1 6 6 6 2 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 EMD00110.1 - 0.004 16.5 8.7 0.004 16.5 8.7 7.1 2 2 4 7 7 7 5 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EMD00110.1 - 0.006 16.8 13.8 0.006 16.8 13.8 8.7 3 2 3 8 8 8 2 Autophagy protein 16 (ATG16) SbcCD_C PF13558.6 EMD00110.1 - 0.047 13.9 0.0 0.7 10.2 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 EMD00110.1 - 0.048 12.3 73.4 0.0065 15.2 12.8 5.2 2 2 2 4 4 4 0 AAA domain ABC_tran PF00005.27 EMD00110.1 - 0.055 14.0 9.2 2 8.9 0.0 4.9 4 1 0 4 4 4 0 ABC transporter RINT1_TIP1 PF04437.13 EMD00111.1 - 2.1e-183 610.8 0.0 3.2e-183 610.2 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family RdRP PF05183.12 EMD00113.1 - 9e-173 576.1 0.0 1.1e-172 575.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase MARVEL PF01284.23 EMD00114.1 - 0.00066 19.7 10.4 0.0014 18.7 10.3 1.7 1 1 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.11 EMD00114.1 - 0.0094 15.9 7.8 0.0094 15.9 7.8 2.0 2 0 0 2 2 2 2 7TM diverse intracellular signalling p450 PF00067.22 EMD00115.1 - 2.5e-54 184.8 0.0 3.4e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-rbx1 PF12678.7 EMD00116.1 - 8.5e-08 32.4 4.6 2.4e-07 31.0 4.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EMD00116.1 - 1e-07 32.1 1.8 1e-07 32.1 1.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EMD00116.1 - 5.9e-05 22.8 0.6 0.00014 21.6 0.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMD00116.1 - 9.5e-05 22.3 2.8 0.00027 20.8 2.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EMD00116.1 - 0.00021 21.1 2.1 0.00051 19.8 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EMD00116.1 - 0.00052 19.8 6.3 0.00083 19.2 2.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EMD00116.1 - 0.00057 19.7 0.4 0.00057 19.7 0.4 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EMD00116.1 - 0.00099 18.7 0.7 0.0022 17.6 0.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EMD00116.1 - 0.0013 18.7 0.4 0.0029 17.6 0.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EMD00116.1 - 0.0061 16.6 0.5 0.015 15.3 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EMD00116.1 - 0.043 13.6 0.7 0.1 12.4 0.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 EMD00116.1 - 0.11 12.9 0.6 0.22 11.9 0.6 1.5 1 0 0 1 1 1 0 RING-like domain YliH PF10799.8 EMD00116.1 - 0.19 11.6 0.8 0.56 10.1 0.8 1.8 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) DUF2726 PF10881.8 EMD00117.1 - 0.61 10.0 7.2 1.3 8.9 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2726) ADH_zinc_N PF00107.26 EMD00118.1 - 2.7e-14 53.3 0.2 6e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMD00118.1 - 1.2e-07 31.6 0.1 3.5e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMD00118.1 - 0.00098 20.2 0.0 0.0018 19.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ras PF00071.22 EMD00119.1 - 2.1e-40 138.0 0.0 2.6e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMD00119.1 - 4e-13 49.6 0.0 6.2e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMD00119.1 - 3.4e-05 23.4 0.0 4.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EMD00119.1 - 0.00019 21.0 0.0 0.0025 17.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMD00119.1 - 0.00098 19.2 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EMD00119.1 - 0.0062 15.8 0.0 0.012 14.8 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain PRK PF00485.18 EMD00119.1 - 0.046 13.5 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 EMD00119.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Flocculin_t3 PF13928.6 EMD00119.1 - 0.17 12.4 0.6 0.34 11.5 0.6 1.5 1 0 0 1 1 1 0 Flocculin type 3 repeat PAS_9 PF13426.7 EMD00120.1 - 6.5e-28 97.0 0.0 2e-16 60.1 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 EMD00120.1 - 3.6e-17 62.4 0.0 2.2e-10 40.7 0.0 3.7 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 EMD00120.1 - 2.1e-14 52.8 6.7 4.6e-14 51.7 6.7 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 EMD00120.1 - 5e-14 52.3 0.0 8.4e-06 25.8 0.0 3.7 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.6 EMD00120.1 - 1.3e-08 35.0 0.0 0.0036 17.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EMD00120.1 - 3.8e-06 27.1 0.0 0.32 11.3 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 EMD00120.1 - 0.0043 17.7 0.0 0.89 10.3 0.0 3.4 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 EMD00120.1 - 0.071 13.2 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 PAS domain Cellulase PF00150.18 EMD00121.1 - 2.2e-08 33.9 2.9 3.8e-08 33.1 2.9 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amidohydro_2 PF04909.14 EMD00121.1 - 0.053 13.3 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase ABM PF03992.16 EMD00122.1 - 0.0011 19.1 1.4 0.12 12.5 0.0 2.7 2 2 1 3 3 3 2 Antibiotic biosynthesis monooxygenase DUF4937 PF16291.5 EMD00122.1 - 0.12 12.6 1.1 0.58 10.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4937 Aldolase_II PF00596.21 EMD00123.1 - 8.1e-27 94.3 0.3 1.4e-26 93.6 0.3 1.3 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.18 EMD00124.1 - 2.3e-11 43.2 0.0 4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD00124.1 - 2.2e-07 30.9 8.5 3.7e-07 30.2 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_2 PF08028.11 EMD00124.1 - 0.19 12.0 2.2 2.6 8.3 0.0 3.2 3 1 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M3 PF01432.20 EMD00125.1 - 2.6e-124 416.0 0.0 4.2e-124 415.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EMD00125.1 - 0.0083 15.8 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M91 PF14891.6 EMD00125.1 - 0.036 14.4 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 Effector protein DUF1643 PF07799.12 EMD00125.1 - 0.068 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) DUF2509 PF10713.9 EMD00125.1 - 0.16 12.1 1.6 0.3 11.2 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) ApoO PF09769.9 EMD00126.1 - 1e-41 142.0 0.1 4.2e-41 139.9 0.0 1.9 2 0 0 2 2 2 1 Apolipoprotein O IBR PF01485.21 EMD00127.1 - 6.3e-10 39.1 49.6 1.1e-05 25.6 15.5 4.3 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain TRAUB PF08164.12 EMD00128.1 - 3.7e-28 97.9 0.4 3.7e-28 97.9 0.4 2.3 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EMD00128.1 - 3.8e-25 89.2 1.5 3.8e-25 89.2 1.5 2.1 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor BSD PF03909.17 EMD00129.1 - 4.9e-18 64.9 1.2 1.1e-17 63.8 1.2 1.6 1 0 0 1 1 1 1 BSD domain DUF5089 PF17002.5 EMD00129.1 - 0.019 14.8 0.4 0.44 10.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) TLE_N PF03920.15 EMD00129.1 - 0.11 12.5 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain PPP4R2 PF09184.11 EMD00129.1 - 0.49 9.9 5.0 1 8.9 5.0 1.6 1 0 0 1 1 1 0 PPP4R2 Suf PF05843.14 EMD00129.1 - 0.52 10.2 4.1 0.17 11.9 0.8 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF883 PF05957.13 EMD00129.1 - 4.9 7.8 10.1 7.9 7.2 0.9 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) PEX11 PF05648.14 EMD00130.1 - 9.4e-69 231.3 1.2 1e-68 231.1 1.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Pkinase PF00069.25 EMD00131.1 - 1.4e-08 34.4 0.0 4.1e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Spem1 PF15670.5 EMD00131.1 - 0.11 12.1 5.6 0.36 10.4 5.9 1.7 2 0 0 2 2 2 0 Spermatid maturation protein 1 EPO_TPO PF00758.18 EMD00131.1 - 0.16 12.0 0.2 0.38 10.8 0.2 1.6 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin Rrn6 PF10214.9 EMD00131.1 - 0.29 9.6 7.2 0.41 9.1 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor UPF0767 PF15990.5 EMD00131.1 - 0.34 11.1 1.4 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 UPF0767 family DUF1501 PF07394.12 EMD00131.1 - 1.4 7.9 5.6 2.3 7.2 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) RNase_H PF00075.24 EMD00132.1 - 1e-07 32.3 0.0 1.5e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 RNase H RNase_H PF00075.24 EMD00133.1 - 0.00011 22.4 0.0 0.0069 16.6 0.0 2.3 2 0 0 2 2 2 2 RNase H Melibiase PF02065.18 EMD00134.1 - 6.2e-139 462.8 0.0 7.8e-139 462.4 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 EMD00134.1 - 4.2e-77 259.1 0.0 5.9e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 EMD00134.1 - 2e-19 69.8 0.0 4e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 EMD00134.1 - 0.00022 20.4 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Lzipper-MIP1 PF14389.6 EMD00135.1 - 0.013 15.8 0.2 0.021 15.1 0.2 1.2 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Isochorismatase PF00857.20 EMD00136.1 - 8.2e-32 110.8 0.0 9.6e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family GFA PF04828.14 EMD00137.1 - 0.00012 22.4 0.5 0.00012 22.4 0.5 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 EMD00137.1 - 0.012 15.2 0.2 0.012 15.2 0.2 2.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain MtrH PF02007.18 EMD00137.1 - 0.045 12.9 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit RPN7 PF10602.9 EMD00138.1 - 5.1e-53 179.3 0.5 7.4e-53 178.8 0.5 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EMD00138.1 - 1.3e-08 35.3 0.0 2.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 EMD00138.1 - 0.006 16.6 0.1 0.016 15.3 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMD00138.1 - 0.051 14.2 1.2 0.13 12.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EMD00138.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Csc2 PF18320.1 EMD00138.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Csc2 Crispr Pox_MCEL PF03291.16 EMD00139.1 - 1.6e-69 234.6 0.0 9.5e-48 163.0 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 EMD00139.1 - 3.5e-07 30.8 0.1 0.00056 20.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EMD00139.1 - 0.00015 22.5 0.0 0.00088 20.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMD00139.1 - 0.0022 17.8 0.0 0.0075 16.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMD00139.1 - 0.0034 18.0 0.0 3.1 8.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain BSP_II PF05432.11 EMD00139.1 - 0.2 11.4 4.1 0.4 10.3 4.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) adh_short PF00106.25 EMD00140.1 - 7.7e-33 113.6 2.7 2.6e-32 111.9 2.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMD00140.1 - 1.2e-29 103.5 6.1 2.9e-27 95.7 6.1 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMD00140.1 - 9.3e-10 38.7 0.5 9.3e-10 38.7 0.5 1.8 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EMD00140.1 - 0.0004 20.4 0.3 0.00074 19.5 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 EMD00140.1 - 0.0012 18.1 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMD00140.1 - 0.0012 18.4 0.8 0.004 16.6 0.8 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EMD00140.1 - 0.0032 17.7 0.2 0.0061 16.8 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EMD00140.1 - 0.039 14.2 0.1 0.08 13.2 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MlrC_C PF07171.12 EMD00140.1 - 0.047 13.9 0.6 0.091 12.9 0.6 1.5 1 0 0 1 1 1 0 MlrC C-terminus GDP_Man_Dehyd PF16363.5 EMD00140.1 - 0.12 11.7 0.7 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase GARS_C PF02843.16 EMD00140.1 - 0.91 9.9 3.2 1.9 8.8 0.1 2.8 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain Spt20 PF12090.8 EMD00141.1 - 3.7 7.1 11.8 7.7 6.1 11.8 1.4 1 0 0 1 1 1 0 Spt20 family DUF21 PF01595.20 EMD00144.1 - 5.1e-34 117.5 0.6 1.2e-33 116.3 0.2 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EMD00144.1 - 4.9e-06 26.9 0.4 0.14 12.6 0.0 2.9 2 0 0 2 2 2 2 CBS domain Vps51 PF08700.11 EMD00146.1 - 3.2e-27 94.4 0.0 6.5e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 EMD00146.1 - 0.0018 17.0 0.0 0.0022 16.7 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family eIF3m_C_helix PF18005.1 EMD00146.1 - 0.037 13.7 1.3 0.13 12.0 0.3 2.1 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix RMI1_N PF08585.12 EMD00147.1 - 1.8e-62 210.9 0.1 2.1e-62 210.7 0.1 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein MLD PF11647.8 EMD00148.1 - 0.022 15.0 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 Membrane Localization Domain Abhydrolase_6 PF12697.7 EMD00149.1 - 2e-11 44.9 2.2 2.8e-11 44.4 2.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMD00149.1 - 5.3e-07 29.1 0.0 1.1e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMD00149.1 - 0.022 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Esterase_phd PF10503.9 EMD00150.1 - 1.3e-11 44.4 0.1 3.1e-11 43.2 0.1 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.12 EMD00150.1 - 0.013 14.2 0.1 0.23 10.1 0.1 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 EMD00150.1 - 0.097 12.3 0.1 0.21 11.2 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 EMD00150.1 - 0.12 12.2 0.0 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EMD00150.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EMD00150.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 EMD00150.1 - 0.19 11.2 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.13 EMD00150.1 - 0.22 11.1 0.0 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Ribonuclease_T2 PF00445.18 EMD00151.1 - 1.1e-40 139.8 0.3 1.8e-40 139.2 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DNA_pol_A_exo1 PF01612.20 EMD00152.1 - 3.7e-41 140.8 0.4 5.8e-41 140.1 0.4 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EMD00152.1 - 4.2e-26 91.5 2.4 4.7e-26 91.3 0.6 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EMD00152.1 - 2.1e-14 53.3 0.7 5.6e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 HRDC domain SURF2 PF05477.11 EMD00152.1 - 0.15 11.8 2.5 0.3 10.7 2.5 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) UPF0203 PF05254.12 EMD00153.1 - 3.1e-28 97.8 3.0 3.6e-28 97.6 3.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 EMD00153.1 - 0.00012 22.4 0.4 0.00024 21.4 0.4 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EMD00153.1 - 0.00069 19.6 2.7 0.04 13.9 0.1 2.3 1 1 2 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 EMD00153.1 - 0.034 14.3 3.1 1.7 8.9 0.3 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 EMD00153.1 - 0.11 13.3 3.7 0.19 12.6 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5339) F-box-like_2 PF13013.6 EMD00154.1 - 0.058 13.4 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 F-box-like domain ECH_1 PF00378.20 EMD00155.1 - 4.2e-45 154.0 0.0 9.9e-45 152.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EMD00155.1 - 3.9e-26 92.3 0.1 4.7e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase V_ATPase_I_N PF18670.1 EMD00155.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain MiAMP1 PF09117.10 EMD00157.1 - 0.053 13.8 1.1 0.35 11.1 0.3 2.0 2 0 0 2 2 2 0 MiAMP1 HATPase_c PF02518.26 EMD00158.1 - 4.5e-20 72.2 0.1 1.1e-19 71.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMD00158.1 - 7.3e-19 68.0 0.0 3.3e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EMD00158.1 - 5e-12 45.7 0.0 1.4e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Adipogenin PF15202.6 EMD00159.1 - 0.17 11.9 0.4 0.33 11.0 0.4 1.5 1 0 0 1 1 1 0 Adipogenin Methyltransf_23 PF13489.6 EMD00160.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.7 2 1 0 2 2 2 0 Methyltransferase domain DUF5597 PF18120.1 EMD00161.1 - 1.4e-24 86.8 0.0 2.8e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 EMD00161.1 - 1.5e-09 37.7 0.0 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 EMD00161.1 - 7.6e-08 32.3 0.0 5.1e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 EMD00161.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Glyco_hydro_5_C PF18564.1 EMD00162.1 - 1.4e-18 67.2 0.2 8.5e-18 64.7 0.2 2.4 1 1 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EMD00162.1 - 2.2e-08 33.9 5.6 8.4e-07 28.7 1.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EMD00162.1 - 0.00036 20.0 1.5 0.056 12.8 0.5 2.3 2 0 0 2 2 2 2 Beta-galactosidase EKLF_TAD1 PF16832.5 EMD00162.1 - 0.068 13.0 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 DnaJ PF00226.31 EMD00163.1 - 5.3e-21 74.5 1.2 1.6e-20 72.9 1.2 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EMD00163.1 - 1.1e-17 63.1 10.8 0.0021 17.8 1.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EMD00163.1 - 3.8e-14 51.6 17.3 0.003 17.5 0.1 7.0 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EMD00163.1 - 1.4e-11 43.6 6.9 0.0092 16.1 0.3 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMD00163.1 - 4.1e-11 42.9 0.6 0.00046 20.3 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EMD00163.1 - 1.6e-09 37.9 6.0 0.00058 20.1 0.1 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EMD00163.1 - 1.1e-08 35.2 11.0 0.024 15.4 0.1 7.0 5 4 2 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMD00163.1 - 1.9e-08 34.7 15.7 0.0002 21.8 0.7 5.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EMD00163.1 - 4.3e-06 27.3 10.4 0.00027 21.5 0.9 5.4 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EMD00163.1 - 1e-05 25.2 2.4 0.4 10.8 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EMD00163.1 - 2.9e-05 23.7 0.4 0.0051 16.5 0.3 4.2 4 1 1 5 5 5 1 TPR repeat PknG_TPR PF16918.5 EMD00163.1 - 0.00043 19.1 0.0 0.0037 16.0 0.0 2.4 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_17 PF13431.6 EMD00163.1 - 0.00082 19.6 7.6 0.0045 17.3 0.1 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMD00163.1 - 0.0026 17.8 5.5 1.3 9.1 0.0 4.5 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EMD00163.1 - 0.0028 18.2 16.4 1.6 9.5 0.1 7.2 9 1 0 9 9 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EMD00163.1 - 0.0028 17.5 11.0 6.8 6.7 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat YfdX PF10938.8 EMD00163.1 - 0.024 14.6 16.0 0.63 10.0 0.4 5.0 3 1 2 5 5 5 0 YfdX protein ANAPC3 PF12895.7 EMD00163.1 - 0.028 14.7 12.1 0.06 13.6 2.7 4.2 5 1 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SHOCT PF09851.9 EMD00163.1 - 4.6 7.1 6.5 5.8 6.8 0.2 3.1 3 0 0 3 3 3 0 Short C-terminal domain Xpo1 PF08389.12 EMD00164.1 - 8.1e-06 26.0 0.2 0.00019 21.5 0.1 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EMD00164.1 - 0.0017 18.2 1.0 0.012 15.5 0.2 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Symplekin_C PF12295.8 EMD00164.1 - 0.056 13.5 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal zf-C2H2 PF00096.26 EMD00166.1 - 0.0044 17.4 4.0 0.38 11.3 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMD00166.1 - 0.013 16.3 2.3 6.3 7.9 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TFIIB PF13453.6 EMD00166.1 - 0.07 12.5 0.2 0.15 11.4 0.2 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger GTP_EFTU PF00009.27 EMD00167.1 - 4.8e-09 36.0 0.0 2.8e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EMD00167.1 - 0.019 14.9 0.5 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ANAPC1 PF12859.7 EMD00169.1 - 8.9e-28 97.4 0.1 8.9e-28 97.4 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 Ribosomal_L31 PF01197.18 EMD00170.1 - 0.0012 19.0 0.1 0.0019 18.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L31 Flavin_Reduct PF01613.18 EMD00171.1 - 2.2e-21 76.5 0.4 1e-20 74.4 0.0 2.2 2 0 0 2 2 2 1 Flavin reductase like domain KH_1 PF00013.29 EMD00171.1 - 3.8e-15 55.5 0.0 0.014 15.2 0.0 5.6 5 0 0 5 5 5 4 KH domain SHOCT PF09851.9 EMD00171.1 - 0.21 11.4 4.2 0.15 11.8 0.8 2.6 2 0 0 2 2 2 0 Short C-terminal domain ECH_1 PF00378.20 EMD00172.1 - 8.8e-14 51.4 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 EMD00172.1 - 0.00063 19.9 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Formyl_trans_N PF00551.19 EMD00172.1 - 0.00072 19.3 0.0 0.0032 17.2 0.0 2.0 1 1 0 1 1 1 1 Formyl transferase PDCD2_C PF04194.13 EMD00173.1 - 1.5e-45 155.4 0.0 2.6e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain KIP1 PF07765.12 EMD00174.1 - 0.04 14.0 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 KIP1-like protein UBM PF14377.6 EMD00174.1 - 0.042 13.3 0.3 0.1 12.1 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin binding region SnoaL PF07366.12 EMD00176.1 - 3.4e-12 46.3 0.0 4.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EMD00176.1 - 5e-08 33.5 0.0 6.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SH3_5 PF08460.10 EMD00176.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain BTB PF00651.31 EMD00177.1 - 2e-05 24.8 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Med11 PF10280.9 EMD00178.1 - 1.7e-33 116.0 0.2 2e-33 115.8 0.2 1.0 1 0 0 1 1 1 1 Mediator complex protein DUF1043 PF06295.12 EMD00178.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) WD40 PF00400.32 EMD00179.1 - 2.1e-45 151.8 16.9 3.6e-08 33.9 0.1 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EMD00179.1 - 4.2e-39 133.8 0.2 6.6e-39 133.1 0.2 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EMD00179.1 - 9.9e-12 45.0 0.6 0.004 17.4 0.1 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMD00179.1 - 0.025 14.4 0.1 1 9.2 0.0 2.8 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 EMD00179.1 - 0.05 12.9 0.1 1.4 8.1 0.0 2.4 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CheZ PF04344.13 EMD00180.1 - 0.0011 18.9 0.6 0.0026 17.7 0.0 1.8 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ BLOC1_2 PF10046.9 EMD00180.1 - 0.0064 16.8 0.1 1.4 9.3 0.0 3.1 3 1 0 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 D-ser_dehydrat PF14031.6 EMD00182.1 - 1.4e-20 73.7 0.0 3e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EMD00182.1 - 3e-14 53.2 0.1 4.4e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA_m1G_MT PF01746.21 EMD00184.1 - 6e-27 94.6 0.1 1.4e-24 86.9 0.1 2.3 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase GRIM-19 PF06212.12 EMD00185.1 - 1.6e-08 34.5 0.3 8e-08 32.3 0.3 1.8 1 1 0 1 1 1 1 GRIM-19 protein DUF4185 PF13810.6 EMD00186.1 - 5.2e-10 39.1 0.2 9.4e-10 38.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Epimerase PF01370.21 EMD00187.1 - 0.054 12.9 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mito_carr PF00153.27 EMD00188.1 - 7.5e-69 227.7 2.8 2.1e-22 78.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_47 PF01532.20 EMD00189.1 - 1e-152 509.3 0.0 5.3e-84 282.7 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 tRNA-synt_2 PF00152.20 EMD00190.1 - 1.3e-81 274.1 0.0 1.6e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EMD00190.1 - 2.9e-06 27.2 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EMD00190.1 - 0.018 14.5 0.1 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 EMD00190.1 - 0.021 14.8 0.0 0.072 13.1 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) AAA PF00004.29 EMD00191.1 - 7.3e-38 130.0 0.0 1.4e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMD00191.1 - 1.8e-08 34.0 0.0 3.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EMD00191.1 - 3.6e-08 33.3 0.0 1.2e-06 28.4 0.0 2.9 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 EMD00191.1 - 2.4e-05 24.6 0.1 0.00035 20.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EMD00191.1 - 9e-05 22.3 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EMD00191.1 - 0.00021 21.7 3.0 0.0019 18.6 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 EMD00191.1 - 0.00071 18.9 0.1 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EMD00191.1 - 0.0015 18.5 0.0 0.0051 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EMD00191.1 - 0.0027 17.5 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EMD00191.1 - 0.0047 16.3 0.1 0.0089 15.4 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EMD00191.1 - 0.0093 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EMD00191.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EMD00191.1 - 0.015 14.9 0.1 0.16 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EMD00191.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EMD00191.1 - 0.028 14.9 0.0 0.12 12.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EMD00191.1 - 0.044 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMD00191.1 - 0.052 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EMD00191.1 - 0.084 12.8 0.0 0.7 9.8 0.0 2.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EMD00191.1 - 0.1 12.8 0.9 0.77 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EMD00191.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 EMD00191.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SYS1 PF09801.9 EMD00193.1 - 1.3e-50 171.3 11.8 1.5e-50 171.1 11.8 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Tim17 PF02466.19 EMD00194.1 - 0.00066 20.0 10.2 0.00095 19.5 9.3 1.8 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TBCC PF07986.12 EMD00195.1 - 2.2e-27 95.2 0.0 3.2e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EMD00195.1 - 0.0007 20.0 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain UCH PF00443.29 EMD00196.1 - 5.1e-33 114.6 0.0 8.8e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EMD00196.1 - 1.6e-29 101.6 3.4 6e-11 42.1 0.1 4.8 5 0 0 5 5 5 3 A repeated domain in UCH-protein UCH_1 PF13423.6 EMD00196.1 - 9.7e-06 25.4 0.0 0.0024 17.5 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Osmo_CC PF08946.10 EMD00196.1 - 0.091 13.0 0.2 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil KGG PF10685.9 EMD00198.1 - 3.7e-09 36.6 1.4 1.2e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 Stress-induced bacterial acidophilic repeat motif Tannase PF07519.11 EMD00199.1 - 9.6e-99 331.4 0.0 1.1e-98 331.2 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EMD00199.1 - 0.00084 18.9 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EMD00199.1 - 0.0074 15.6 2.6 0.012 14.9 0.0 2.2 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMD00199.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Antimicrobial17 PF08129.11 EMD00199.1 - 0.21 11.6 0.1 0.42 10.6 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta enterocin family Esterase PF00756.20 EMD00199.1 - 0.25 11.0 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Glyco_hydro_47 PF01532.20 EMD00200.1 - 8.2e-189 628.2 0.0 4.1e-188 625.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Gln-synt_C PF00120.24 EMD00203.1 - 1e-64 218.8 0.0 1.5e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EMD00203.1 - 9.1e-14 51.9 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.25 EMD00204.1 - 4.4e-20 72.0 0.0 5.7e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMD00204.1 - 8.7e-16 58.2 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase LDcluster4 PF18306.1 EMD00204.1 - 0.063 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 SLOG cluster4 family Epimerase PF01370.21 EMD00204.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EMD00204.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PDEase_I_N PF08499.12 EMD00205.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal HRXXH PF13933.6 EMD00206.1 - 0.064 12.8 0.3 0.079 12.5 0.3 1.1 1 0 0 1 1 1 0 Putative peptidase family Complex1_LYR_2 PF13233.6 EMD00207.1 - 1.4e-12 48.2 0.1 2e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EMD00207.1 - 0.00038 20.4 0.0 0.00071 19.6 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) NAD_binding_10 PF13460.6 EMD00208.1 - 1.8e-23 83.4 0.0 2.1e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMD00208.1 - 3.9e-11 43.0 0.2 9.6e-11 41.7 0.1 1.7 2 1 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EMD00208.1 - 4.9e-08 32.7 0.0 1.7e-07 31.0 0.0 1.7 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EMD00208.1 - 0.013 15.0 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EMD00208.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EMD00208.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EMD00208.1 - 0.14 11.3 0.1 2.9 7.0 0.1 2.5 2 1 1 3 3 3 0 Male sterility protein GST_N_3 PF13417.6 EMD00209.1 - 3.3e-21 75.5 0.1 1.3e-20 73.6 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMD00209.1 - 5.3e-20 71.5 0.2 1.6e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMD00209.1 - 4e-13 49.5 0.1 6.9e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMD00209.1 - 4.9e-09 36.1 0.4 1.5e-08 34.5 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMD00209.1 - 0.0011 19.2 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EMD00209.1 - 0.0077 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 EMD00209.1 - 0.015 16.0 0.0 0.039 14.7 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C PF00043.25 EMD00209.1 - 0.046 13.9 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMD00209.1 - 0.063 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SPX PF03105.19 EMD00210.1 - 7.5e-42 144.6 2.6 1.8e-41 143.3 2.6 1.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_2 PF13923.6 EMD00210.1 - 0.00017 21.3 12.7 0.00037 20.3 12.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EMD00210.1 - 0.0035 17.5 11.8 0.0071 16.5 10.7 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EMD00210.1 - 0.0078 16.1 10.5 0.016 15.0 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EMD00210.1 - 0.022 14.6 4.9 0.043 13.7 4.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 EMD00210.1 - 0.034 14.0 9.8 0.057 13.3 9.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EMD00210.1 - 0.052 13.5 9.7 0.093 12.7 9.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF4501 PF14946.6 EMD00210.1 - 0.2 11.7 2.8 0.34 11.0 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) zf-RING_UBOX PF13445.6 EMD00210.1 - 0.62 10.1 6.9 1.4 9.0 6.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger HypA PF01155.19 EMD00210.1 - 1.1 9.3 4.6 1.5 8.9 2.9 2.1 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_4 PF14570.6 EMD00210.1 - 7.8 6.4 10.2 22 4.9 10.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DnaJ PF00226.31 EMD00211.1 - 2.3e-24 85.3 0.9 2.3e-24 85.3 0.9 2.5 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 EMD00211.1 - 1.7e-11 44.1 3.3 1.7e-11 44.1 3.3 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMD00211.1 - 8.3e-08 32.4 5.6 9.8e-08 32.2 2.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EMD00211.1 - 8.4e-06 26.1 3.6 0.0041 17.4 0.9 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EMD00211.1 - 2.2e-05 24.9 4.6 0.064 14.1 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EMD00211.1 - 3.4e-05 24.0 5.8 0.016 15.6 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EMD00211.1 - 0.2 11.7 8.8 0.79 9.8 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EMD00211.1 - 8.3 7.1 8.4 5.6 7.6 1.1 3.3 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats JAB PF01398.21 EMD00213.1 - 5.2e-14 52.2 0.0 8.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EMD00213.1 - 6.6e-07 29.5 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 EMD00213.1 - 4.5e-05 23.2 0.1 0.00011 21.9 0.1 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Cas_GSU0054 PF09609.10 EMD00213.1 - 0.022 13.5 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) DUF1744 PF08490.12 EMD00215.1 - 2.5e-149 497.2 0.1 4.4e-149 496.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EMD00215.1 - 1.2e-80 271.2 0.0 4.4e-80 269.4 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EMD00215.1 - 4.7e-16 58.5 0.1 1.1e-13 50.7 0.1 3.0 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EMD00215.1 - 1.4e-09 38.0 0.1 3.5e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EMD00215.1 - 9.6e-05 22.4 0.0 0.00052 20.0 0.0 2.3 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.8 EMD00216.1 - 1.4e-29 101.9 0.5 2.1e-29 101.3 0.2 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) DUF1682 PF07946.14 EMD00216.1 - 1.7 7.8 9.0 2.2 7.4 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Methyltransf_32 PF13679.6 EMD00218.1 - 0.045 13.7 0.4 0.051 13.6 0.4 1.3 1 0 0 1 1 1 0 Methyltransferase domain DivIVA PF05103.13 EMD00218.1 - 0.061 13.4 5.1 0.076 13.1 5.1 1.2 1 0 0 1 1 1 0 DivIVA protein Herpes_UL25 PF01499.16 EMD00218.1 - 0.16 10.5 1.8 0.16 10.5 1.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF883 PF05957.13 EMD00218.1 - 0.19 12.4 7.9 0.55 10.9 3.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Aldedh PF00171.22 EMD00221.1 - 4.7e-153 510.0 0.1 5.3e-153 509.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_11 PF14833.6 EMD00221.1 - 0.068 13.4 0.4 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RecA PF00154.21 EMD00221.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein TPP_enzyme_N PF02776.18 EMD00222.1 - 2e-34 118.7 1.6 2.2e-31 108.8 0.1 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EMD00222.1 - 2.6e-18 66.3 0.3 8.1e-18 64.7 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMD00222.1 - 2.3e-09 37.1 0.0 4.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Pkinase PF00069.25 EMD00223.1 - 3.6e-58 197.0 0.0 6.5e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD00223.1 - 2.2e-40 138.6 0.0 3.7e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMD00223.1 - 2.1e-10 40.4 0.0 1.3e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EMD00223.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EMD00223.1 - 0.083 11.6 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase IpgD PF05925.12 EMD00223.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Rsa3 PF14615.6 EMD00224.1 - 4.3e-19 67.8 0.1 6.9e-19 67.2 0.1 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DUF1387 PF07139.11 EMD00224.1 - 0.029 14.1 0.4 0.036 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TraG-D_C PF12696.7 EMD00224.1 - 0.16 12.0 0.1 0.54 10.2 0.1 1.8 2 1 0 2 2 2 0 TraM recognition site of TraD and TraG HA PF03457.14 EMD00227.1 - 2.9 8.3 5.7 14 6.1 5.6 2.0 1 1 0 1 1 1 0 Helicase associated domain SurE PF01975.17 EMD00228.1 - 9.7e-27 94.0 0.0 1.3e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Aconitase PF00330.20 EMD00229.1 - 1.4e-150 502.4 0.0 1.7e-150 502.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EMD00229.1 - 2.3e-45 154.1 0.0 3.9e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 EMD00230.1 - 1.8e-09 37.6 2.1 1.8e-09 37.6 2.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMD00230.1 - 0.0031 17.9 0.8 0.0031 17.9 0.8 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF4188 PF13826.6 EMD00230.1 - 0.041 14.2 0.9 2.4 8.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) zf-C2H2_2 PF12756.7 EMD00230.1 - 0.061 13.7 0.7 0.061 13.7 0.7 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EMD00230.1 - 0.061 13.3 0.5 0.15 12.1 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EMD00230.1 - 0.066 14.1 0.2 0.066 14.1 0.2 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger Hexapep PF00132.24 EMD00231.1 - 2.7e-08 33.2 13.2 1.5e-06 27.7 4.7 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EMD00231.1 - 3.2e-08 33.2 11.1 2e-07 30.6 5.9 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DnaJ PF00226.31 EMD00232.1 - 1.2e-08 34.9 0.4 1.2e-08 34.9 0.4 1.9 2 0 0 2 2 2 1 DnaJ domain Phasin PF05597.11 EMD00232.1 - 0.0055 16.7 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Phage_lysis PF03245.13 EMD00232.1 - 0.044 13.9 1.5 0.21 11.7 1.5 2.1 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein SlyX PF04102.12 EMD00232.1 - 0.47 11.1 3.8 20 5.9 0.6 2.6 1 1 1 2 2 2 0 SlyX Pro-kuma_activ PF09286.11 EMD00234.1 - 1.6e-38 132.2 1.0 1.1e-37 129.4 0.8 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EMD00234.1 - 0.0021 17.4 0.5 0.0039 16.5 0.5 1.3 1 0 0 1 1 1 1 Subtilase family Lactamase_B PF00753.27 EMD00235.1 - 3.9e-18 66.2 1.9 3.5e-16 59.8 1.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EMD00235.1 - 2e-16 59.7 0.0 3.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EMD00235.1 - 1.2e-06 28.2 0.6 5.8e-06 26.0 0.6 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EMD00235.1 - 0.025 14.5 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EMD00235.1 - 0.21 11.0 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain SAT PF16073.5 EMD00236.1 - 2e-79 266.7 0.5 6.9e-79 265.0 0.0 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 EMD00236.1 - 1.7e-77 260.4 0.0 5e-77 258.9 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EMD00236.1 - 1.6e-43 149.4 0.0 3.9e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMD00236.1 - 1.5e-34 118.5 3.1 5.1e-34 116.8 3.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EMD00236.1 - 1.5e-26 92.5 3.7 6e-13 48.9 0.3 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 EMD00236.1 - 6.7e-16 58.4 0.0 1.7e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EMD00236.1 - 4.2e-06 27.2 0.1 2.6e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EMD00236.1 - 0.00028 20.3 0.1 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain AflR PF08493.10 EMD00236.1 - 1.6 8.1 11.1 2.6 7.5 2.3 3.2 2 1 1 3 3 3 0 Aflatoxin regulatory protein EcoRII-N PF09217.10 EMD00237.1 - 0.031 14.0 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal DiS_P_DiS PF06750.13 EMD00238.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain NAD_binding_10 PF13460.6 EMD00239.1 - 5.5e-17 62.2 0.0 7.2e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EMD00239.1 - 0.0081 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EMD00239.1 - 0.093 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RecX PF02631.16 EMD00239.1 - 0.16 12.4 0.1 0.29 11.6 0.1 1.3 1 0 0 1 1 1 0 RecX family Zn_clus PF00172.18 EMD00242.1 - 5.1e-08 32.9 13.4 1.2e-07 31.7 13.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EMD00242.1 - 1.3e-05 25.3 13.0 0.00012 22.3 1.8 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMD00242.1 - 0.00026 21.3 3.9 0.00026 21.3 3.9 4.5 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMD00242.1 - 0.0057 17.4 1.0 0.0057 17.4 1.0 4.5 4 1 0 4 4 4 2 C2H2-type zinc finger adh_short_C2 PF13561.6 EMD00244.1 - 3.6e-57 193.6 2.7 5.5e-57 193.0 2.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMD00244.1 - 4.6e-49 166.5 5.3 6e-49 166.2 5.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMD00244.1 - 2.8e-13 50.2 1.1 3.8e-13 49.7 1.1 1.1 1 0 0 1 1 1 1 KR domain DFP PF04127.15 EMD00244.1 - 0.092 12.6 4.2 0.26 11.1 4.2 1.7 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 EMD00244.1 - 0.3 11.0 4.1 0.5 10.2 4.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IMPDH PF00478.25 EMD00244.1 - 0.47 9.4 7.6 0.77 8.7 2.2 2.6 1 1 2 3 3 3 0 IMP dehydrogenase / GMP reductase domain QRPTase_C PF01729.19 EMD00246.1 - 1.2e-53 181.3 0.0 1.6e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EMD00246.1 - 1.4e-21 76.4 0.0 4.2e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Peripla_BP_4 PF13407.6 EMD00246.1 - 0.016 14.8 0.0 0.16 11.5 0.1 2.0 1 1 1 2 2 2 0 Periplasmic binding protein domain ADH_zinc_N PF00107.26 EMD00246.1 - 0.046 13.7 0.3 0.24 11.4 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PTS_IIB PF02302.17 EMD00246.1 - 0.095 13.4 0.5 0.2 12.3 0.5 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Prenylcys_lyase PF07156.14 EMD00247.1 - 1.5e-88 297.3 0.0 2e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EMD00247.1 - 1.1e-12 47.9 0.3 3e-12 46.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMD00247.1 - 2.1e-10 40.5 0.0 5.5e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EMD00247.1 - 8.4e-08 32.2 1.4 1e-05 25.3 1.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMD00247.1 - 0.00023 21.2 0.1 0.013 15.5 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMD00247.1 - 0.019 14.2 0.2 0.033 13.4 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EMD00247.1 - 0.022 14.0 0.7 0.091 12.0 0.2 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EMD00247.1 - 0.037 14.6 0.5 0.53 10.9 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMD00247.1 - 0.098 11.7 0.8 0.15 11.1 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A E1_dh PF00676.20 EMD00247.1 - 0.1 11.5 1.1 0.18 10.7 1.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component ApbA PF02558.16 EMD00247.1 - 0.15 11.7 0.2 0.29 10.8 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 EMD00247.1 - 0.22 10.9 2.2 4.4 6.6 1.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HTH_18 PF12833.7 EMD00249.1 - 0.035 14.4 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GTP_EFTU PF00009.27 EMD00250.1 - 5.1e-35 120.8 3.5 2.6e-33 115.2 3.5 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EMD00250.1 - 2.9e-25 88.4 0.0 7.7e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EMD00250.1 - 1.1e-09 38.3 0.2 8e-09 35.6 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EMD00250.1 - 5.8e-06 26.3 1.0 5.6e-05 23.1 0.2 2.4 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 EMD00250.1 - 6.2e-06 25.8 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 EMD00250.1 - 6.2e-05 23.3 6.5 0.00082 19.7 0.7 3.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 FeoB_N PF02421.18 EMD00250.1 - 7.8e-05 22.2 0.2 0.0002 20.9 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B IF2_N PF04760.15 EMD00250.1 - 0.00012 21.8 0.0 0.00039 20.2 0.0 2.0 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.9 EMD00250.1 - 0.0019 18.0 0.2 0.0066 16.2 0.2 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 EMD00250.1 - 0.0025 16.9 1.4 0.0025 16.9 1.4 2.1 3 0 0 3 3 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EMD00250.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EMD00250.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1_Xtn PF16897.5 EMD00250.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 EMD00250.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Jun PF03957.13 EMD00250.1 - 0.02 14.8 0.9 0.14 12.0 1.3 2.2 2 0 0 2 2 2 0 Jun-like transcription factor MutL_C PF08676.11 EMD00250.1 - 0.13 12.0 0.6 0.81 9.5 0.0 2.5 3 0 0 3 3 3 0 MutL C terminal dimerisation domain GTP_EFTU_D4 PF14578.6 EMD00250.1 - 0.27 11.1 2.8 0.78 9.7 0.7 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DDRGK PF09756.9 EMD00250.1 - 1 8.9 25.3 0.09 12.4 9.6 2.9 2 0 0 2 2 2 0 DDRGK domain AAA_23 PF13476.6 EMD00250.1 - 3.1 8.3 0.0 3.1 8.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain ATP11 PF06644.11 EMD00250.1 - 9.9 5.9 13.0 16 5.1 0.7 2.5 2 0 0 2 2 2 0 ATP11 protein MFS_1 PF07690.16 EMD00251.1 - 1.6e-25 89.8 38.9 1.7e-25 89.7 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMD00251.1 - 0.75 8.6 22.9 0.023 13.6 10.4 3.0 3 0 0 3 3 3 0 Sugar (and other) transporter Peptidase_C12 PF01088.21 EMD00252.1 - 1.3e-54 185.2 0.0 7.4e-39 133.7 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EMD00252.1 - 0.049 13.5 0.2 0.12 12.3 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases DEAD PF00270.29 EMD00254.1 - 4e-42 143.9 0.2 5.9e-42 143.4 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMD00254.1 - 8.8e-28 96.9 0.9 2e-26 92.5 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMD00254.1 - 0.00097 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EMD00254.1 - 0.02 14.3 0.1 0.041 13.2 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GRP PF07172.11 EMD00254.1 - 0.15 12.7 17.5 0.27 11.9 17.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family Rhomboid PF01694.22 EMD00255.1 - 1.2e-18 67.6 15.8 2.6e-18 66.4 15.8 1.6 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EMD00255.1 - 0.014 15.9 0.6 0.037 14.6 0.3 1.8 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) SURF1 PF02104.15 EMD00255.1 - 0.048 13.9 0.2 0.077 13.2 0.2 1.3 1 0 0 1 1 1 0 SURF1 family Ureidogly_lyase PF04115.12 EMD00256.1 - 8.2e-65 218.1 0.0 1.1e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase Acetyltransf_13 PF13880.6 EMD00257.1 - 3.6e-25 87.7 0.0 6.2e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EMD00257.1 - 1.2e-13 50.6 0.6 2e-13 49.9 0.6 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF2924 PF11149.8 EMD00257.1 - 0.069 13.5 0.2 0.32 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) LEF-4 PF05098.12 EMD00257.1 - 0.078 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Late expression factor 4 (LEF-4) COesterase PF00135.28 EMD00258.1 - 2.9e-75 254.1 0.1 3.9e-75 253.7 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMD00258.1 - 2.1e-07 31.0 0.2 1.1e-06 28.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMD00258.1 - 0.43 10.0 2.9 0.27 10.7 0.7 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family RPE65 PF03055.15 EMD00259.1 - 3.3e-103 346.4 0.0 3.8e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Peptidase_C14 PF00656.22 EMD00260.1 - 9.6e-62 209.1 0.0 1.4e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain HNH PF01844.23 EMD00262.1 - 0.0049 17.0 3.6 0.012 15.8 3.6 1.6 1 0 0 1 1 1 1 HNH endonuclease C1_1 PF00130.22 EMD00262.1 - 0.071 13.0 0.2 0.14 12.1 0.2 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HAD_2 PF13419.6 EMD00263.1 - 2.7e-10 40.6 0.0 4.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMD00263.1 - 4.4e-06 26.7 0.0 7.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EMD00263.1 - 1.2e-05 25.7 0.0 1.6e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aa_trans PF01490.18 EMD00264.1 - 2e-51 175.0 37.8 2.5e-51 174.7 37.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 EMD00264.1 - 0.00017 20.6 48.8 0.0068 15.3 48.8 2.1 1 1 0 1 1 1 1 Amino acid permease CBS PF00571.28 EMD00265.1 - 2.8e-35 120.5 5.5 1.8e-09 37.9 0.0 5.3 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 EMD00265.1 - 9e-12 44.8 0.0 3.9e-11 42.7 0.0 2.2 2 1 0 2 2 2 1 PB1 domain Ribosomal_S26e PF01283.19 EMD00266.1 - 7.3e-52 174.4 8.5 8.8e-52 174.1 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EMD00266.1 - 0.022 14.7 0.4 0.058 13.4 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 EMD00266.1 - 0.075 12.8 0.4 0.12 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) DUF1918 PF08940.11 EMD00266.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) VanZ PF04892.12 EMD00267.1 - 2.2e-08 34.8 0.6 3e-08 34.4 0.6 1.2 1 0 0 1 1 1 1 VanZ like family Phage_holin_2_4 PF16082.5 EMD00267.1 - 0.04 13.7 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4131 PF13567.6 EMD00267.1 - 4.6 6.9 10.4 1.6 8.3 2.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Bromodomain PF00439.25 EMD00268.1 - 1.9e-17 63.1 0.5 3.6e-17 62.2 0.5 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EMD00268.1 - 0.00024 21.0 0.0 0.00074 19.5 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated SPARC_Ca_bdg PF10591.9 EMD00268.1 - 0.17 12.2 0.9 0.49 10.7 0.9 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF29 PF01724.16 EMD00268.1 - 8.5 6.6 7.0 2.2 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF29 ubiquitin PF00240.23 EMD00270.1 - 1.2e-13 50.6 0.0 2.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 EMD00270.1 - 1.1e-11 44.6 3.8 1.1e-11 44.6 3.8 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 EMD00270.1 - 0.00038 20.2 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EMD00270.1 - 0.039 14.5 0.0 0.11 13.1 0.0 1.9 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Chitin_bind_1 PF00187.19 EMD00272.1 - 1.5e-08 35.0 22.1 2e-08 34.5 22.1 1.3 1 0 0 1 1 1 1 Chitin recognition protein OTU PF02338.19 EMD00273.1 - 7.3e-06 26.5 0.0 1.1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 EMD00273.1 - 0.01 16.3 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 PB1 PF00564.24 EMD00273.1 - 0.059 13.3 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 PB1 domain Bromodomain PF00439.25 EMD00274.1 - 4.6e-35 119.5 3.7 3.2e-17 62.4 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EMD00274.1 - 9.6e-17 61.0 0.3 2.3e-16 59.7 0.3 1.7 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.14 EMD00274.1 - 0.29 9.4 2.1 0.55 8.5 2.1 1.4 1 0 0 1 1 1 0 CDC45-like protein FMO-like PF00743.19 EMD00275.1 - 2.9e-08 32.6 0.0 3.1e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EMD00275.1 - 3.9e-08 33.4 0.1 4.4e-08 33.2 0.1 1.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EMD00275.1 - 4.2e-06 26.3 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EMD00275.1 - 4.2e-05 23.3 0.0 4.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EMD00275.1 - 6e-05 23.1 0.1 6.8e-05 22.9 0.1 1.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EMD00275.1 - 0.00016 21.0 0.0 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMD00275.1 - 0.00044 20.8 0.1 0.00071 20.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMD00275.1 - 0.0021 17.2 0.1 0.0024 17.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EMD00275.1 - 0.003 16.7 0.1 0.0045 16.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 EMD00275.1 - 0.0032 16.8 0.6 0.0042 16.3 0.6 1.2 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 EMD00275.1 - 0.0039 16.1 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 MCRA family Lycopene_cycl PF05834.12 EMD00275.1 - 0.017 14.2 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EMD00275.1 - 0.028 13.1 0.7 0.04 12.6 0.6 1.3 1 1 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EMD00275.1 - 0.038 13.2 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EMD00275.1 - 0.063 12.6 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EMD00275.1 - 0.12 12.3 0.2 0.15 11.9 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA PF00004.29 EMD00276.1 - 4.7e-45 153.3 0.4 1.2e-44 151.9 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EMD00276.1 - 3.5e-09 36.5 0.1 2.2e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EMD00276.1 - 4.7e-09 36.4 0.7 1.9e-08 34.4 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMD00276.1 - 4.8e-08 33.3 0.0 1.2e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EMD00276.1 - 1.6e-07 31.9 0.4 4.2e-05 24.0 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EMD00276.1 - 3.4e-06 26.4 0.3 6.6e-06 25.5 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 EMD00276.1 - 4.9e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EMD00276.1 - 0.00014 22.2 3.4 0.0081 16.4 0.1 2.8 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.12 EMD00276.1 - 0.00033 20.5 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EMD00276.1 - 0.00079 20.0 0.0 0.0024 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EMD00276.1 - 0.0009 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EMD00276.1 - 0.0011 19.3 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EMD00276.1 - 0.0012 18.2 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 EMD00276.1 - 0.0012 18.3 0.1 0.0065 16.0 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EMD00276.1 - 0.0015 18.6 0.1 0.0074 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMD00276.1 - 0.0018 18.0 0.0 0.0041 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EMD00276.1 - 0.0022 17.9 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 EMD00276.1 - 0.0053 16.7 0.2 0.11 12.4 0.0 2.7 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 EMD00276.1 - 0.0058 16.5 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EMD00276.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EMD00276.1 - 0.0078 16.4 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EMD00276.1 - 0.008 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EMD00276.1 - 0.01 15.3 0.0 0.55 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein DUF3450 PF11932.8 EMD00276.1 - 0.011 15.1 1.0 0.024 14.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IstB_IS21 PF01695.17 EMD00276.1 - 0.012 15.3 0.1 0.039 13.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 EMD00276.1 - 0.012 15.4 0.3 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EMD00276.1 - 0.021 14.8 1.4 0.32 10.9 0.0 2.8 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EMD00276.1 - 0.021 14.6 0.2 0.053 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EMD00276.1 - 0.036 14.6 0.6 5.6 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EMD00276.1 - 0.041 13.2 1.7 0.52 9.6 0.0 2.6 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 EMD00276.1 - 0.065 12.9 0.1 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 EMD00276.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 EMD00276.1 - 0.071 12.7 1.3 0.29 10.7 0.1 2.3 2 1 0 3 3 3 0 AAA domain Viral_Hsp90 PF03225.14 EMD00276.1 - 0.08 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_19 PF13245.6 EMD00276.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EMD00276.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HIP1_clath_bdg PF16515.5 EMD00276.1 - 0.84 10.3 4.7 7 7.3 3.1 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pyridoxal_deC PF00282.19 EMD00277.1 - 1.4e-77 261.0 0.0 2.9e-69 233.6 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EMD00277.1 - 2.3e-08 33.7 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase PUF PF00806.19 EMD00277.1 - 6.6e-07 28.7 0.0 5.4 6.9 0.0 5.7 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat Aminotran_5 PF00266.19 EMD00277.1 - 2.9e-06 26.5 0.0 5.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 EMD00277.1 - 0.0086 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS CcmH PF03918.14 EMD00279.1 - 0.15 11.4 0.5 0.45 9.8 0.1 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Cpn60_TCP1 PF00118.24 EMD00280.1 - 6e-155 516.6 5.9 6.9e-155 516.4 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 EMD00280.1 - 0.085 13.3 0.1 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch U3_assoc_6 PF08640.11 EMD00283.1 - 7.9e-23 80.3 0.2 3.7e-21 75.0 0.0 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EMD00283.1 - 1.8e-06 28.2 0.2 0.13 13.2 0.2 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 EMD00283.1 - 0.006 16.6 0.0 0.24 11.4 0.0 2.5 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 EMD00283.1 - 0.024 13.8 0.3 0.24 10.5 0.3 2.2 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference MutL_C PF08676.11 EMD00284.1 - 0.033 14.0 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 MutL C terminal dimerisation domain YccV-like PF08755.11 EMD00285.1 - 2.2e-26 92.2 0.0 5.6e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EMD00285.1 - 1e-12 47.9 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 EMD00285.1 - 3.7e-05 23.5 0.0 7.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMD00285.1 - 5.5e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EMD00285.1 - 0.052 14.1 0.2 0.13 12.8 0.2 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CRAL_TRIO PF00650.20 EMD00286.1 - 2.8e-23 82.4 0.0 4.2e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EMD00286.1 - 6.5e-08 32.6 0.0 1.7e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ifi-6-16 PF06140.13 EMD00287.1 - 1.4e-06 28.1 1.0 2.5e-06 27.3 1.0 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ala_racemase_N PF01168.20 EMD00287.1 - 0.0028 17.4 0.2 1.1 8.8 0.1 2.1 2 0 0 2 2 2 2 Alanine racemase, N-terminal domain Glyco_hydro_16 PF00722.21 EMD00288.1 - 9.2e-08 31.8 0.3 2.1e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SAM_2 PF07647.17 EMD00289.1 - 1.1e-06 28.7 0.2 1.9e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EMD00289.1 - 0.00075 19.9 0.1 0.0015 18.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Cnn_1N PF07989.11 EMD00291.1 - 4.7e-15 55.5 15.0 1.2e-14 54.2 6.2 2.2 1 1 0 2 2 2 2 Centrosomin N-terminal motif 1 HIP1_clath_bdg PF16515.5 EMD00291.1 - 0.076 13.6 16.0 0.052 14.2 12.2 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cob_adeno_trans PF01923.18 EMD00291.1 - 0.094 12.8 7.1 1 9.5 1.1 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Spore_III_AB PF09548.10 EMD00291.1 - 0.15 12.1 7.1 0.35 11.0 7.0 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Fzo_mitofusin PF04799.13 EMD00291.1 - 0.28 10.7 7.9 0.28 10.7 2.1 2.2 1 1 1 2 2 2 0 fzo-like conserved region Tup_N PF08581.10 EMD00291.1 - 0.41 11.0 9.2 0.096 13.0 3.7 2.3 1 1 1 2 2 2 0 Tup N-terminal zf-ZPR1 PF03367.13 EMD00291.1 - 0.57 10.0 2.5 0.67 9.8 1.8 1.4 1 1 0 1 1 1 0 ZPR1 zinc-finger domain GIT_CC PF16559.5 EMD00291.1 - 1 9.3 7.3 8.9 6.3 1.0 3.0 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Atg14 PF10186.9 EMD00291.1 - 1.2 8.1 7.0 1.5 7.8 7.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 EMD00291.1 - 1.2 9.4 9.5 1.2 9.5 0.7 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein FUSC PF04632.12 EMD00291.1 - 7.8 4.9 7.9 8.5 4.8 7.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.15 EMD00291.1 - 8 6.3 17.5 9.8 6.0 0.7 3.3 1 1 1 3 3 3 0 Septum formation initiator SGT1 PF07093.11 EMD00292.1 - 5.3e-94 315.8 12.7 2.3e-85 287.2 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein STAS_2 PF13466.6 EMD00293.1 - 0.0067 16.8 4.5 0.27 11.6 0.3 2.8 2 1 1 3 3 3 2 STAS domain Actin PF00022.19 EMD00294.1 - 2.6e-125 418.2 0.0 3e-125 418.0 0.0 1.0 1 0 0 1 1 1 1 Actin MBOAT PF03062.19 EMD00295.1 - 3.3e-51 174.7 7.5 3.3e-51 174.7 7.5 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family T4SS_CagC PF16943.5 EMD00295.1 - 0.061 13.5 0.5 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system F-box-like PF12937.7 EMD00296.1 - 0.0099 15.8 0.3 0.025 14.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like NeA_P2 PF12312.8 EMD00296.1 - 0.095 12.1 4.1 0.25 10.7 4.1 1.7 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Macoilin PF09726.9 EMD00297.1 - 2.6 6.5 5.9 3.5 6.1 5.9 1.1 1 0 0 1 1 1 0 Macoilin family PIP5K PF01504.18 EMD00298.1 - 7.3e-97 323.9 0.0 1.1e-96 323.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.19 EMD00299.1 - 2.7e-26 91.7 0.1 2.7e-26 91.7 0.1 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family Aa_trans PF01490.18 EMD00301.1 - 4.9e-60 203.4 21.3 5.8e-60 203.1 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CLP_protease PF00574.23 EMD00302.1 - 3.4e-76 255.2 0.0 4.4e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 EMD00302.1 - 0.082 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase ECH_1 PF00378.20 EMD00302.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Methyltransf_31 PF13847.6 EMD00305.1 - 1.5e-05 24.8 0.0 1.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMD00305.1 - 0.00071 20.2 0.0 0.00099 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMD00305.1 - 0.0029 18.3 0.0 0.0041 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMD00305.1 - 0.0036 18.0 0.0 0.0048 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_43 PF04616.14 EMD00306.1 - 6.1e-25 88.1 0.0 1.2e-24 87.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 F-box-like PF12937.7 EMD00307.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMD00307.1 - 0.0069 16.2 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain Radial_spoke_3 PF06098.11 EMD00307.1 - 0.06 12.6 0.2 0.3 10.3 0.2 1.9 2 0 0 2 2 2 0 Radial spoke protein 3 PhyH PF05721.13 EMD00309.1 - 0.019 15.2 0.1 0.046 14.0 0.1 1.7 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) MAPEG PF01124.18 EMD00310.1 - 3.7e-09 36.6 2.2 3.7e-09 36.6 2.2 1.4 2 0 0 2 2 2 1 MAPEG family Glyco_hydro_32N PF00251.20 EMD00311.1 - 2.7e-44 152.0 1.9 4.4e-44 151.3 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EMD00311.1 - 3.5e-28 98.6 0.1 7.3e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 EMD00311.1 - 8.7e-06 25.9 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) EPSP_synthase PF00275.20 EMD00311.1 - 0.027 13.2 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Phenol_monoox PF04663.12 EMD00311.1 - 0.096 12.8 0.6 0.28 11.3 0.6 1.8 1 0 0 1 1 1 0 Phenol hydroxylase conserved region Glt_symporter PF03616.14 EMD00311.1 - 0.5 9.0 1.8 0.73 8.4 1.8 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Sporozoite_P67 PF05642.11 EMD00311.1 - 9.3 4.2 13.3 15 3.5 13.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med9 PF07544.13 EMD00312.1 - 6.1e-14 51.9 0.8 8.7e-14 51.4 0.8 1.3 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 EMD00312.1 - 0.0077 16.5 3.0 0.0078 16.5 3.0 1.3 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Formin_GBD_N PF18382.1 EMD00312.1 - 0.012 16.0 0.2 0.022 15.2 0.0 1.6 2 0 0 2 2 2 0 Formin N-terminal GTPase-binding domain Phage_GP20 PF06810.11 EMD00312.1 - 0.095 12.5 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 iPGM_N PF06415.13 EMD00313.1 - 2.3e-77 259.3 0.0 3.6e-77 258.7 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EMD00313.1 - 7.7e-71 238.4 0.1 9.2e-71 238.1 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EMD00313.1 - 1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EMD00313.1 - 0.00029 20.3 0.0 0.00061 19.3 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Rho_N PF07498.12 EMD00313.1 - 0.0067 16.3 0.0 0.26 11.3 0.0 2.6 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain Alk_phosphatase PF00245.20 EMD00313.1 - 0.013 14.5 0.1 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 Alkaline phosphatase DUF4973 PF16343.5 EMD00313.1 - 0.016 15.3 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4973) AP_endonuc_2 PF01261.24 EMD00313.1 - 0.036 13.5 0.0 0.081 12.4 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel SHMT PF00464.19 EMD00314.1 - 1.5e-197 656.0 0.0 1.8e-197 655.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EMD00314.1 - 7.1e-06 25.4 0.0 2.6e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMD00314.1 - 0.095 11.2 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EMD00314.1 - 0.12 11.7 0.2 0.34 10.2 0.2 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IL17R_D_N PF16742.5 EMD00314.1 - 0.15 12.1 0.0 0.48 10.5 0.0 1.8 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Sec7 PF01369.20 EMD00315.1 - 4e-27 95.1 0.0 6.8e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EMD00315.1 - 3.4e-16 59.7 0.0 7.5e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain LETM1 PF07766.13 EMD00316.1 - 3.2e-17 62.8 0.4 3e-12 46.4 0.6 2.1 2 0 0 2 2 2 2 LETM1-like protein SAP PF02037.27 EMD00316.1 - 0.023 14.5 0.1 0.052 13.3 0.1 1.6 1 0 0 1 1 1 0 SAP domain RNA_polI_A34 PF08208.11 EMD00317.1 - 4.4e-35 121.7 0.4 4.4e-35 121.7 0.4 5.3 3 1 1 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 EMD00318.1 - 4.7e-44 150.4 0.0 9.6e-44 149.4 0.0 1.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 EMD00318.1 - 0.0089 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Metallopep PF12044.8 EMD00319.1 - 2.5e-171 570.0 0.0 3e-171 569.8 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Astacin PF01400.24 EMD00319.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) PRIMA1 PF16101.5 EMD00319.1 - 0.14 12.2 2.0 0.32 11.0 2.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Whi5 PF08528.11 EMD00320.1 - 1.5e-08 34.0 0.0 2.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Aminotran_1_2 PF00155.21 EMD00322.1 - 1.7e-36 126.1 0.0 2.1e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMD00322.1 - 0.071 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Clathrin PF00637.20 EMD00323.1 - 2.2e-16 60.0 0.2 6.4e-16 58.5 0.1 1.8 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.32 EMD00323.1 - 0.0011 19.7 0.9 14 6.8 0.0 4.6 5 0 0 5 5 4 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 EMD00323.1 - 0.0074 16.6 0.4 0.02 15.2 0.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EMD00323.1 - 0.036 14.0 0.2 0.077 13.0 0.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 EMD00323.1 - 0.07 12.9 1.1 0.16 11.8 1.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger Vps39_1 PF10366.9 EMD00323.1 - 0.084 13.2 0.1 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_UBOX PF13445.6 EMD00323.1 - 0.17 12.0 0.5 0.45 10.6 0.2 1.9 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_1 PF14446.6 EMD00323.1 - 0.17 11.8 0.5 0.36 10.8 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 EMD00323.1 - 0.19 11.7 0.1 0.43 10.5 0.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_7 PF13176.6 EMD00323.1 - 0.22 11.6 4.1 1.1 9.5 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat NBP1 PF08537.10 EMD00323.1 - 0.25 10.7 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 zf-rbx1 PF12678.7 EMD00323.1 - 6.4 7.1 6.5 0.33 11.3 0.5 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain DUF155 PF02582.14 EMD00324.1 - 2.3e-51 174.4 0.1 3.1e-51 174.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.12 EMD00324.1 - 0.00017 21.2 0.1 0.00038 20.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EMD00324.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin MT0933_antitox PF14013.6 EMD00325.1 - 0.0063 16.8 5.6 0.6 10.4 1.0 2.1 1 1 1 2 2 2 2 MT0933-like antitoxin protein Ykof PF07615.11 EMD00325.1 - 0.028 14.9 0.1 0.037 14.5 0.1 1.1 1 0 0 1 1 1 0 YKOF-related Family PP28 PF10252.9 EMD00327.1 - 2.1e-27 95.4 20.1 2.1e-27 95.4 20.1 3.2 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 SDA1 PF05285.12 EMD00327.1 - 0.13 11.7 37.0 0.16 11.4 37.0 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 EMD00327.1 - 2 8.9 33.2 0.15 12.5 1.7 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Frag1 PF10277.9 EMD00328.1 - 4.6e-39 134.2 7.4 4.6e-39 134.2 7.4 2.5 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 EMD00328.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RRG8 PF17068.5 EMD00329.1 - 0.094 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial UPRTase PF14681.6 EMD00330.1 - 3.8e-28 98.4 0.3 1.2e-27 96.7 0.1 1.9 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_16 PF13191.6 EMD00330.1 - 0.00013 22.4 0.1 0.00031 21.2 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain HAD PF12710.7 EMD00330.1 - 0.00017 22.1 0.9 0.0022 18.4 0.1 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 EMD00330.1 - 0.0013 19.2 0.1 0.013 16.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EMD00330.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_33 PF13671.6 EMD00330.1 - 0.0027 17.8 0.2 0.01 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EMD00330.1 - 0.0045 16.6 0.0 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EMD00330.1 - 0.0047 17.4 0.1 0.013 16.0 0.1 1.9 1 1 0 1 1 1 1 ABC transporter Vps23_core PF09454.10 EMD00330.1 - 0.0073 16.2 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 1 Vps23 core domain AAA_18 PF13238.6 EMD00330.1 - 0.0076 16.8 0.0 0.022 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 EMD00330.1 - 0.012 14.7 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EMD00330.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EMD00330.1 - 0.015 15.0 3.6 1 9.0 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 EMD00330.1 - 0.025 15.0 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EMD00330.1 - 0.027 14.7 0.1 0.059 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Pribosyltran PF00156.27 EMD00330.1 - 0.032 13.7 0.3 0.069 12.7 0.3 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain NB-ARC PF00931.22 EMD00330.1 - 0.051 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 EMD00330.1 - 0.058 13.5 0.1 0.24 11.5 0.0 2.1 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EMD00330.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMD00330.1 - 0.068 12.9 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 EMD00330.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Viral_helicase1 PF01443.18 EMD00330.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EMD00330.1 - 0.65 10.3 2.2 3.3 8.1 0.0 3.1 4 2 1 5 5 3 0 AAA domain Cullin PF00888.22 EMD00331.1 - 4.1e-17 62.0 0.0 1e-16 60.8 0.0 1.6 1 1 0 1 1 1 1 Cullin family DUF5635 PF18685.1 EMD00331.1 - 0.16 11.9 1.0 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5635) Sugar_tr PF00083.24 EMD00332.1 - 6.1e-96 322.0 25.6 7.5e-96 321.7 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EMD00332.1 - 3.4e-25 88.7 33.4 3.4e-25 88.7 33.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily NB PF04159.13 EMD00332.1 - 0.26 11.4 0.9 6.9 6.8 0.0 3.0 3 0 0 3 3 3 0 NB glycoprotein Herpes_LMP1 PF05297.11 EMD00332.1 - 3.9 6.6 12.8 43 3.1 12.8 2.2 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Cys_Met_Meta_PP PF01053.20 EMD00334.1 - 8.4e-29 100.3 0.0 1.1e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EMD00334.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Nrap_D4 PF17405.2 EMD00335.1 - 1e-63 214.6 0.0 1.7e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 EMD00335.1 - 1.2e-58 197.4 0.1 2.2e-58 196.6 0.1 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EMD00335.1 - 3e-47 160.2 0.0 4.8e-45 153.0 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 EMD00335.1 - 1.3e-45 155.1 0.1 2.4e-45 154.3 0.1 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EMD00335.1 - 1.1e-43 149.1 0.0 4.4e-43 147.1 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EMD00335.1 - 1.5e-35 122.3 0.0 2.8e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 PCMT PF01135.19 EMD00336.1 - 1.6e-68 230.6 0.0 1.9e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EMD00336.1 - 1.1e-07 31.7 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMD00336.1 - 6.2e-06 26.8 0.0 1.6e-05 25.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EMD00336.1 - 0.0001 22.4 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMD00336.1 - 0.00022 20.7 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EMD00336.1 - 0.00038 20.3 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMD00336.1 - 0.00053 20.6 0.0 0.0014 19.2 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.10 EMD00336.1 - 0.00068 19.4 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MetW PF07021.12 EMD00336.1 - 0.0018 17.9 0.1 0.0041 16.7 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Fibrillarin PF01269.17 EMD00336.1 - 0.038 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin MTS PF05175.14 EMD00336.1 - 0.043 13.4 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 EMD00336.1 - 0.054 13.6 0.0 0.23 11.6 0.0 1.9 1 1 1 2 2 2 0 FtsJ-like methyltransferase RrnaAD PF00398.20 EMD00336.1 - 0.063 12.3 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 EMD00336.1 - 0.13 13.3 0.0 0.89 10.6 0.0 2.3 1 1 2 3 3 3 0 Methyltransferase domain Methyltransf_4 PF02390.17 EMD00336.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 EMD00336.1 - 0.18 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EMD00336.1 - 0.22 10.9 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RNA_bind PF08675.11 EMD00337.1 - 0.089 12.8 0.2 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 RNA binding domain AA_permease_2 PF13520.6 EMD00338.1 - 7e-36 124.0 38.4 2.1e-35 122.4 38.4 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EMD00338.1 - 6.2e-06 25.1 37.8 3.3e-05 22.7 37.8 2.1 1 1 0 1 1 1 1 Amino acid permease DUF2854 PF11016.8 EMD00338.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Glyco_hydro_17 PF00332.18 EMD00339.1 - 4.9e-08 32.9 5.4 3e-07 30.3 0.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Titin_Z PF09042.11 EMD00339.1 - 0.082 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Titin Z zf-C2H2_4 PF13894.6 EMD00340.1 - 0.016 16.0 16.3 0.1 13.5 0.1 3.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMD00340.1 - 0.025 15.0 0.2 0.025 15.0 0.2 4.2 4 1 1 5 5 5 0 Zinc finger, C2H2 type DUF3431 PF11913.8 EMD00341.1 - 3.8e-23 82.4 0.0 4.6e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SprT-like PF10263.9 EMD00342.1 - 3.1e-38 130.1 0.9 5.5e-38 129.3 0.9 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EMD00342.1 - 0.059 13.3 4.3 0.15 12.0 4.3 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EMD00342.1 - 0.1 12.7 0.9 0.19 11.8 0.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Mog1 PF04603.12 EMD00343.1 - 8.2e-38 129.9 0.0 9.7e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 Ran-interacting Mog1 protein PCI PF01399.27 EMD00344.1 - 1.9e-10 41.2 0.2 4.1e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 PCI domain HAD_SAK_1 PF10307.9 EMD00345.1 - 7.8e-73 244.6 0.0 1.2e-72 244.0 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins TPR_1 PF00515.28 EMD00347.1 - 1.4e-32 110.2 17.4 5.4e-05 22.8 0.0 13.7 14 0 0 14 14 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 EMD00347.1 - 8.5e-29 97.3 49.4 0.0033 17.4 0.0 16.9 18 0 0 18 18 16 8 Tetratricopeptide repeat TPR_19 PF14559.6 EMD00347.1 - 1e-27 96.4 39.4 1.1e-08 35.4 1.6 11.8 10 2 3 13 13 12 6 Tetratricopeptide repeat TPR_14 PF13428.6 EMD00347.1 - 4.4e-25 86.2 55.6 0.00052 20.6 0.6 16.8 13 4 4 17 17 16 7 Tetratricopeptide repeat TPR_17 PF13431.6 EMD00347.1 - 1e-24 85.1 18.9 0.0072 16.6 0.1 13.3 13 1 1 14 14 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 EMD00347.1 - 3.5e-23 82.0 65.3 2.9e-06 27.8 2.1 15.0 12 3 6 18 18 16 9 Tetratricopeptide repeat TPR_8 PF13181.6 EMD00347.1 - 4.6e-23 79.4 25.7 0.054 13.7 0.0 14.1 15 1 1 16 16 14 6 Tetratricopeptide repeat TPR_11 PF13414.6 EMD00347.1 - 5.9e-22 77.1 24.0 0.00023 20.8 0.1 12.5 12 2 1 13 13 13 5 TPR repeat TPR_7 PF13176.6 EMD00347.1 - 2.6e-15 55.2 29.9 0.024 14.7 0.0 12.8 14 0 0 14 14 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 EMD00347.1 - 6.5e-13 48.8 57.4 0.0021 18.3 0.2 13.5 12 2 2 14 14 13 5 Tetratricopeptide repeat TPR_6 PF13174.6 EMD00347.1 - 1.8e-10 40.7 26.5 0.11 13.2 0.0 13.9 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_20 PF14561.6 EMD00347.1 - 1.3e-08 35.0 21.6 0.49 10.8 0.2 10.2 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_22 PF18833.1 EMD00347.1 - 5.2e-08 32.9 0.0 3.4e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EMD00347.1 - 6.6e-05 22.5 1.8 0.014 14.9 0.1 3.4 4 0 0 4 4 3 1 Coatomer epsilon subunit ANAPC3 PF12895.7 EMD00347.1 - 0.00025 21.2 26.3 2.7 8.3 0.0 9.5 7 3 2 9 9 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EMD00347.1 - 0.00054 20.1 38.4 0.065 13.4 1.3 10.7 11 1 1 12 12 10 3 Tetratricopeptide repeat TPR_5 PF12688.7 EMD00347.1 - 0.0011 19.2 5.9 0.039 14.2 0.2 4.6 6 0 0 6 6 3 1 Tetratrico peptide repeat HrpB1_HrpK PF09613.10 EMD00347.1 - 0.0073 16.0 4.4 0.35 10.5 0.1 4.7 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) ChAPs PF09295.10 EMD00347.1 - 0.03 13.3 4.4 27 3.6 0.0 5.1 5 1 1 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) NuDC PF16273.5 EMD00347.1 - 0.032 14.8 0.1 0.12 12.9 0.1 1.9 1 0 0 1 1 1 0 Nuclear distribution C domain TPR_3 PF07720.12 EMD00347.1 - 0.065 13.3 1.4 4.4 7.4 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMD00347.1 - 0.16 11.9 0.1 0.16 11.9 0.1 10.6 13 0 0 13 13 12 0 Tetratricopeptide repeat DUF627 PF04781.12 EMD00347.1 - 0.27 11.3 4.2 0.4 10.7 0.1 3.5 3 1 0 3 3 2 0 Protein of unknown function (DUF627) TPR_4 PF07721.14 EMD00347.1 - 5 8.1 38.6 0.39 11.5 0.1 10.7 10 0 0 10 10 8 0 Tetratricopeptide repeat TerB PF05099.13 EMD00347.1 - 9.4 6.2 18.5 0.69 9.9 0.6 4.5 5 0 0 5 5 4 0 Tellurite resistance protein TerB RCC1 PF00415.18 EMD00348.1 - 1.5e-31 108.8 1.4 1.3e-07 32.2 0.0 7.0 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EMD00348.1 - 9.8e-17 60.3 28.4 1.8e-13 49.9 0.4 6.9 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat DUF1663 PF07909.11 EMD00348.1 - 0.012 14.4 0.1 0.022 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) RRM_1 PF00076.22 EMD00352.1 - 6.2e-19 67.6 0.2 1.3e-18 66.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EMD00352.1 - 7.2e-05 22.8 0.0 0.00036 20.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EMD00352.1 - 0.024 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EMD00352.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCHC PF00098.23 EMD00353.1 - 2.1e-12 46.5 11.1 8.2e-06 25.7 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EMD00353.1 - 2.7e-08 33.5 0.1 5e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EMD00353.1 - 2.1e-05 24.4 10.6 0.00063 19.6 2.0 2.5 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_6 PF15288.6 EMD00353.1 - 0.00021 21.1 8.9 0.026 14.3 0.5 3.1 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 EMD00353.1 - 0.00084 19.0 5.0 0.43 10.3 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EMD00353.1 - 0.0089 15.8 0.5 0.0089 15.8 0.5 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CHY PF05495.12 EMD00353.1 - 0.21 12.1 2.1 1.2 9.6 2.1 2.0 1 1 0 1 1 1 0 CHY zinc finger zf-HIT PF04438.16 EMD00353.1 - 2.6 8.0 4.0 6 6.8 0.6 2.2 2 0 0 2 2 2 0 HIT zinc finger Gpr1_Fun34_YaaH PF01184.19 EMD00354.1 - 2.2e-32 112.4 26.7 2.7e-32 112.1 26.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1844 PF08899.11 EMD00354.1 - 6.2 7.2 5.6 60 4.0 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1844) UQ_con PF00179.26 EMD00355.1 - 1.4e-38 131.7 0.0 1.6e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EMD00355.1 - 0.011 16.1 0.0 0.013 15.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain Cupin_8 PF13621.6 EMD00357.1 - 1.1e-36 126.9 0.0 1.5e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EMD00357.1 - 3.3e-06 26.8 0.0 0.00034 20.2 0.0 2.4 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.22 EMD00357.1 - 0.0017 18.7 0.0 0.017 15.6 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Pkinase PF00069.25 EMD00358.1 - 5.6e-19 68.5 0.0 5.9e-15 55.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EMD00358.1 - 2.7e-09 36.7 0.0 6.7e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase MFS_1 PF07690.16 EMD00360.1 - 1.2e-32 113.2 29.1 1.2e-32 113.2 29.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Flavi_NS2B PF01002.19 EMD00360.1 - 0.086 12.7 0.2 2.4 8.0 0.2 2.8 3 0 0 3 3 3 0 Flavivirus non-structural protein NS2B MFS_1_like PF12832.7 EMD00360.1 - 4.1 6.2 14.3 0.021 13.7 1.7 2.7 2 1 2 4 4 4 0 MFS_1 like family MatE PF01554.18 EMD00361.1 - 4.7e-05 23.1 1.4 4.7e-05 23.1 1.4 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EMD00361.1 - 5e-05 23.4 0.8 5e-05 23.4 0.8 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain DEAD PF00270.29 EMD00362.1 - 2.5e-45 154.4 0.1 4.3e-45 153.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMD00362.1 - 2.5e-20 72.9 0.1 2.3e-19 69.8 0.0 2.6 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMD00362.1 - 3.8e-07 30.3 0.0 5.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EMD00362.1 - 0.0029 16.9 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase adh_short PF00106.25 EMD00363.1 - 5.5e-34 117.3 0.0 9.1e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMD00363.1 - 1.9e-23 83.3 0.0 2.8e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMD00363.1 - 3.5e-07 30.3 2.6 1.8e-06 28.0 2.6 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMD00363.1 - 0.0018 17.8 0.2 0.0037 16.7 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peroxidase_2 PF01328.17 EMD00365.1 - 1.8e-43 149.3 0.0 2.4e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Ribosomal_L7Ae PF01248.26 EMD00366.1 - 9.4e-27 92.6 1.1 1.1e-26 92.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EMD00366.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Vac_ImportDeg PF09783.9 EMD00367.1 - 5.3e-28 97.9 0.0 4.8e-27 94.8 0.0 2.5 2 1 0 2 2 2 1 Vacuolar import and degradation protein Csm2_III-A PF03750.13 EMD00368.1 - 0.1 13.4 1.1 0.2 12.5 0.2 1.9 2 0 0 2 2 2 0 Csm2 Type III-A TMEM240 PF15207.6 EMD00368.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 TMEM240 family AMPKBI PF04739.15 EMD00370.1 - 0.072 13.4 0.2 0.077 13.3 0.2 1.1 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain TPP_enzyme_N PF02776.18 EMD00375.1 - 3.5e-34 117.9 0.2 9.5e-34 116.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EMD00375.1 - 6.4e-21 74.5 0.0 1.5e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EMD00375.1 - 1.3e-14 54.2 2.8 3.1e-12 46.5 0.1 2.9 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GST_N PF02798.20 EMD00376.1 - 1.5e-14 54.1 0.0 2.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EMD00376.1 - 2.2e-12 47.0 0.0 3.4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMD00376.1 - 2.6e-12 46.8 0.0 5.4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EMD00376.1 - 2.7e-12 46.9 0.0 4.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMD00376.1 - 2.5e-11 43.7 0.0 4.8e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMD00376.1 - 1.6e-06 28.0 0.0 3.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_trans_1_2 PF13524.6 EMD00376.1 - 0.019 15.3 0.1 9.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 SKG6 PF08693.10 EMD00377.1 - 0.028 13.8 5.5 0.086 12.3 5.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MLANA PF14991.6 EMD00377.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A DUF3535 PF12054.8 EMD00379.1 - 1.7e-123 413.1 0.1 1.7e-122 409.8 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EMD00379.1 - 3.9e-65 219.9 0.0 1.1e-64 218.4 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EMD00379.1 - 3.5e-19 69.2 0.0 1.4e-18 67.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EMD00379.1 - 2.7e-16 58.3 14.8 0.007 16.5 0.0 11.2 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.6 EMD00379.1 - 8.3e-08 32.5 17.5 0.0016 18.8 0.1 8.0 7 2 0 8 8 8 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EMD00379.1 - 1.2e-06 29.0 0.1 0.018 15.6 0.0 3.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 EMD00379.1 - 0.00061 20.1 1.5 1.4 9.2 0.0 5.4 7 0 0 7 7 7 1 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 EMD00379.1 - 0.001 18.7 1.9 1.1 8.7 0.0 3.9 3 2 1 4 4 4 2 CLASP N terminal UME PF08064.13 EMD00379.1 - 0.053 13.4 2.0 5.2 7.1 0.0 4.7 6 1 1 7 7 7 0 UME (NUC010) domain DUF2428 PF10350.9 EMD00379.1 - 0.061 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) AMP-binding PF00501.28 EMD00380.1 - 1.3e-71 241.4 0.1 1.6e-71 241.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMD00380.1 - 3.4e-20 72.8 0.1 9.6e-20 71.3 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 EMD00381.1 - 9.5e-21 73.7 18.8 8.9e-07 29.5 0.6 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMD00381.1 - 8.7e-16 58.0 0.0 0.031 14.6 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EMD00381.1 - 0.001 18.1 0.1 1.1 8.2 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EMD00381.1 - 0.0033 17.3 0.1 1.5 8.7 0.0 3.0 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EMD00381.1 - 0.011 15.1 0.3 0.64 9.3 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal BAG PF02179.16 EMD00382.1 - 2.7e-19 69.4 0.5 4.8e-19 68.6 0.5 1.4 1 0 0 1 1 1 1 BAG domain YL1 PF05764.13 EMD00382.1 - 0.0001 22.5 4.2 0.00015 22.0 4.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein ubiquitin PF00240.23 EMD00382.1 - 0.0007 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rrn6 PF10214.9 EMD00382.1 - 0.018 13.6 2.2 0.021 13.4 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SPATA3 PF15662.5 EMD00382.1 - 0.075 13.7 5.1 0.13 12.8 5.1 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family TUG-UBL1 PF11470.8 EMD00382.1 - 0.095 12.9 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain Cwf_Cwc_15 PF04889.12 EMD00382.1 - 0.16 11.6 6.7 0.055 13.2 3.3 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PGA2 PF07543.12 EMD00382.1 - 0.25 11.3 6.4 0.18 11.8 4.6 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 CDC45 PF02724.14 EMD00382.1 - 0.28 9.4 2.2 0.33 9.2 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EMD00382.1 - 0.37 8.8 4.0 0.51 8.3 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spt5_N PF11942.8 EMD00382.1 - 1.4 10.0 11.0 0.29 12.1 7.1 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SIR2 PF02146.17 EMD00383.1 - 3.3e-27 95.5 0.0 2.2e-26 92.9 0.0 2.1 1 1 0 1 1 1 1 Sir2 family MCR PF18509.1 EMD00383.1 - 0.0079 15.8 0.2 0.026 14.1 0.2 1.9 1 0 0 1 1 1 1 Magnetochrome domain Paired_CXXCH_1 PF09699.10 EMD00383.1 - 0.22 11.3 1.3 0.49 10.2 1.3 1.6 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) Med16 PF11635.8 EMD00384.1 - 1.7e-71 241.2 1.4 1e-70 238.7 1.4 1.8 1 1 0 1 1 1 1 Mediator complex subunit 16 SOAR PF16533.5 EMD00386.1 - 0.11 12.5 1.9 0.41 10.7 0.5 2.5 1 1 1 2 2 2 0 STIM1 Orai1-activating region MMS19_N PF14500.6 EMD00386.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Lectin_N PF03954.14 EMD00386.1 - 0.17 11.6 3.1 0.4 10.4 0.1 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain CsbD PF05532.12 EMD00388.1 - 0.0015 18.4 7.1 0.019 14.9 2.0 2.4 2 1 0 2 2 2 2 CsbD-like Peptidase_S8 PF00082.22 EMD00392.1 - 1.5e-35 123.0 0.0 2.7e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Iso_dh PF00180.20 EMD00393.1 - 4.9e-81 272.6 0.0 6.1e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Plasmid_stab_B PF10784.9 EMD00393.1 - 0.11 12.4 0.1 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Plasmid stability protein DIT1_PvcA PF05141.12 EMD00395.1 - 2.5e-77 260.1 0.0 3.4e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 EMD00395.1 - 1.6e-25 90.4 0.1 6.5e-25 88.4 0.1 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PP2C PF00481.21 EMD00396.1 - 1.6e-21 77.1 0.0 8.8e-20 71.4 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EMD00396.1 - 0.014 15.3 0.1 0.58 10.0 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Methyltransf_23 PF13489.6 EMD00397.1 - 1.8e-11 44.1 0.0 2.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMD00397.1 - 2.1e-10 41.1 0.0 4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMD00397.1 - 5.3e-09 36.7 0.0 1.3e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMD00397.1 - 5.2e-08 33.5 0.0 1.3e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMD00397.1 - 0.00027 20.8 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMD00397.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GST_N_3 PF13417.6 EMD00398.1 - 3.6e-09 36.9 0.0 5.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMD00398.1 - 0.00051 20.3 0.1 0.001 19.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMD00399.1 - 4e-29 100.7 0.3 3.6e-28 97.7 0.3 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMD00399.1 - 2.2e-06 27.8 0.0 4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMD00399.1 - 0.00094 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acetyltransf_CG PF14542.6 EMD00399.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Amidohydro_3 PF07969.11 EMD00400.1 - 7.2e-05 22.4 0.4 0.0024 17.4 0.4 2.1 1 1 1 2 2 2 2 Amidohydrolase family Pribosyl_synth PF14572.6 EMD00402.1 - 1.8e-36 125.9 0.9 4.9e-33 114.7 0.4 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EMD00402.1 - 1.7e-35 121.4 0.0 3.7e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EMD00402.1 - 5.8e-14 51.9 0.1 1.2e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EMD00402.1 - 0.019 14.4 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ras PF00071.22 EMD00403.1 - 1.4e-18 67.0 0.0 3e-18 65.9 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EMD00403.1 - 0.00057 20.1 0.0 0.0016 18.6 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EMD00403.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EMD00403.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EMD00403.1 - 0.11 12.6 0.1 0.21 11.7 0.0 1.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EMD00403.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EMD00403.1 - 0.15 11.5 0.0 0.85 9.0 0.0 2.1 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_29 PF13555.6 EMD00403.1 - 0.16 11.8 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bestrophin PF01062.21 EMD00405.1 - 5.4e-33 114.6 0.4 9.4e-33 113.9 0.4 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FAD_binding_3 PF01494.19 EMD00406.1 - 1.2e-18 67.5 0.0 2e-18 66.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMD00406.1 - 6.3e-11 42.4 0.6 9.9e-05 22.1 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMD00406.1 - 3.4e-10 39.6 0.4 0.00061 19.1 0.2 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMD00406.1 - 2.5e-06 27.6 0.0 5.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EMD00406.1 - 3.2e-06 26.1 0.0 0.028 13.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EMD00406.1 - 3.3e-06 26.5 0.1 7.5e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EMD00406.1 - 0.00034 20.1 0.0 0.00053 19.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EMD00406.1 - 0.0028 16.8 2.0 0.45 9.5 0.1 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 EMD00406.1 - 0.0028 16.6 1.4 0.049 12.5 0.2 2.4 2 1 0 3 3 3 1 Tryptophan halogenase SE PF08491.10 EMD00406.1 - 0.0034 16.5 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 EMD00406.1 - 0.0081 16.7 0.0 0.11 13.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EMD00406.1 - 0.023 13.8 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 EMD00406.1 - 0.041 13.1 0.0 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 EMD00406.1 - 0.06 12.6 1.9 0.23 10.7 0.5 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 EMD00406.1 - 0.073 13.0 0.1 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EMD00406.1 - 0.17 11.1 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EMD00407.1 - 1.8e-29 102.8 46.2 9.3e-26 90.6 21.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EMD00408.1 - 4.8e-17 61.9 55.0 2.6e-12 46.3 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rrn6 PF10214.9 EMD00409.1 - 1.6e-138 463.6 16.3 3.3e-138 462.6 16.3 1.5 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Phage_min_cap2 PF06152.11 EMD00409.1 - 0.023 13.6 3.6 0.036 13.0 3.6 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 FAD_binding_3 PF01494.19 EMD00410.1 - 2e-17 63.5 0.2 3.8e-17 62.6 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EMD00410.1 - 0.00012 21.8 0.5 0.054 13.1 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMD00410.1 - 0.00017 20.9 1.1 0.044 13.0 0.1 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMD00410.1 - 0.00031 21.2 0.5 0.24 12.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMD00410.1 - 0.019 15.0 0.5 2.9 7.9 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF5397 PF17375.2 EMD00410.1 - 0.023 14.4 0.2 0.045 13.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5397) NAD_binding_8 PF13450.6 EMD00410.1 - 0.12 12.6 0.1 0.34 11.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_trans_2_3 PF13632.6 EMD00411.1 - 2.1e-51 174.6 3.3 2.1e-51 174.6 3.3 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EMD00411.1 - 1.6e-07 31.3 0.0 2.4e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EMD00411.1 - 6.9e-06 26.1 0.1 2e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EMD00411.1 - 0.00081 18.9 0.1 0.0046 16.4 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 21 Lactamase_B PF00753.27 EMD00412.1 - 3.4e-16 59.8 0.3 6.1e-16 59.0 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EMD00412.1 - 0.004 16.7 0.2 0.0063 16.0 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF677 PF05055.12 EMD00414.1 - 0.31 9.9 0.3 0.52 9.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) MFS_1 PF07690.16 EMD00415.1 - 2e-06 27.0 32.1 5.7e-06 25.5 25.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 EMD00417.1 - 4e-07 30.1 0.0 1.4e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EMD00417.1 - 5.9e-05 22.9 0.0 0.00041 20.2 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EMD00417.1 - 9.9e-05 23.4 0.0 0.00057 20.9 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glyoxalase_3 PF13468.6 EMD00419.1 - 3e-07 30.7 0.0 1.9e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain DnaJ PF00226.31 EMD00420.1 - 1e-17 64.0 0.4 3.3e-17 62.4 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain FAA_hydrolase PF01557.18 EMD00421.1 - 5e-61 206.2 0.0 6.1e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ANAPC_CDC26 PF10471.9 EMD00422.1 - 0.014 16.2 0.5 0.85 10.5 0.0 3.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Yippee-Mis18 PF03226.14 EMD00424.1 - 1.9e-17 63.4 1.7 2.1e-17 63.2 1.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.9 EMD00424.1 - 0.023 15.0 0.6 0.023 15.0 0.6 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) PGPGW PF09656.10 EMD00427.1 - 0.076 12.5 0.5 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) Peptidase_M20 PF01546.28 EMD00428.1 - 1.1e-05 25.3 0.1 1.4e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EMD00428.1 - 4.8e-05 23.2 0.0 9.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain VASP_tetra PF08776.11 EMD00428.1 - 0.074 12.6 0.1 0.074 12.6 0.1 1.7 2 0 0 2 2 2 0 VASP tetramerisation domain ketoacyl-synt PF00109.26 EMD00429.1 - 1.1e-78 264.3 0.0 2.4e-78 263.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EMD00429.1 - 5.8e-59 199.7 1.2 5.8e-59 199.7 1.2 3.0 3 1 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EMD00429.1 - 2.7e-37 129.0 0.1 5e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EMD00429.1 - 1.5e-34 118.5 0.3 3.6e-34 117.3 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EMD00429.1 - 3.8e-25 89.4 0.0 9e-24 84.9 0.0 2.7 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EMD00429.1 - 8.8e-20 70.8 5.5 4.1e-09 36.6 0.4 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EMD00429.1 - 3.4e-08 33.9 0.4 3.1e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EMD00429.1 - 3e-07 30.0 0.9 4.5e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EMD00429.1 - 0.0015 17.9 0.1 0.004 16.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lipase_3 PF01764.25 EMD00429.1 - 0.023 14.5 0.0 0.62 9.9 0.0 2.5 2 0 0 2 2 2 0 Lipase (class 3) DUF1729 PF08354.10 EMD00431.1 - 5e-142 473.0 0.0 7.7e-142 472.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EMD00431.1 - 1.1e-59 202.6 1.1 6.7e-58 196.7 0.0 3.0 3 1 0 3 3 3 1 Acyl transferase domain SAT PF16073.5 EMD00431.1 - 1.1e-25 90.8 0.3 1.8e-25 90.0 0.3 1.4 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EMD00431.1 - 2.6e-25 88.4 0.1 7.5e-25 86.9 0.1 1.7 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EMD00431.1 - 1.2e-07 32.0 0.0 3.2e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_meander PF17951.1 EMD00431.1 - 0.00041 20.2 0.0 0.00091 19.1 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain Fas_alpha_ACP PF18325.1 EMD00432.1 - 3.8e-47 160.7 0.0 1e-46 159.2 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 EMD00432.1 - 2.1e-36 125.5 0.0 4.5e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 EMD00432.1 - 2.3e-21 76.5 0.2 7.9e-21 74.8 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EMD00432.1 - 5.4e-15 55.5 0.0 1.3e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EMD00432.1 - 1.2e-12 47.9 0.0 6.1e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EMD00432.1 - 1.7e-09 37.4 0.0 7.4e-09 35.3 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 EMD00432.1 - 0.0026 17.7 2.3 0.0038 17.2 0.0 2.4 3 0 0 3 3 3 1 KR domain AdoHcyase_NAD PF00670.21 EMD00432.1 - 0.0027 17.8 0.1 0.0064 16.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_synt_2 PF02719.15 EMD00432.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMD00432.1 - 0.046 13.2 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EMD00432.1 - 0.05 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 EMD00432.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF5547 PF17701.1 EMD00432.1 - 0.15 11.9 0.2 0.6 10.0 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5547) MFS_1 PF07690.16 EMD00433.1 - 2e-37 129.0 54.9 2e-37 129.0 54.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMD00433.1 - 1.9e-06 27.0 14.1 1.9e-06 27.0 14.1 3.5 2 2 1 3 3 3 2 Sugar (and other) transporter Hydrolase_4 PF12146.8 EMD00434.1 - 4.6e-06 26.1 0.2 0.016 14.5 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EMD00434.1 - 0.00063 19.5 0.1 0.23 11.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMD00434.1 - 0.00074 20.2 5.2 0.00074 20.2 5.2 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EMD00434.1 - 0.0089 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 EMD00434.1 - 0.064 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase Zn_clus PF00172.18 EMD00435.1 - 9.6e-09 35.2 9.8 1.8e-08 34.4 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUD1_2 PF18457.1 EMD00435.1 - 0.18 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 Methyltransf_2 PF00891.18 EMD00436.1 - 6.8e-11 41.9 0.0 1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FSH1 PF03959.13 EMD00437.1 - 9e-22 77.8 0.0 1.9e-20 73.5 0.0 2.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ADH_zinc_N_2 PF13602.6 EMD00438.1 - 5.3e-24 85.8 0.0 8.2e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EMD00438.1 - 6.7e-15 55.2 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMD00438.1 - 0.032 14.1 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Fungal_trans_2 PF11951.8 EMD00440.1 - 5.8e-07 28.7 1.7 1.6e-06 27.2 0.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1793 PF08760.11 EMD00441.1 - 4.4e-70 235.4 0.2 8.7e-70 234.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EMD00441.1 - 5.2e-64 215.1 1.2 1.3e-49 168.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EMD00441.1 - 7.4e-39 133.9 0.4 1.2e-38 133.2 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 EMD00441.1 - 0.0057 16.2 0.1 0.013 15.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Ndufs5 PF10200.9 EMD00442.1 - 0.00075 19.7 0.1 0.0011 19.1 0.1 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 EMD00442.1 - 0.0011 19.3 1.2 0.0021 18.4 1.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 EMD00442.1 - 0.065 13.5 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Man-6-P_recep PF02157.15 EMD00443.1 - 2e-15 56.6 0.0 2.7e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EMD00443.1 - 6.4e-07 29.5 0.0 2.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 EMD00443.1 - 2.8e-06 27.4 0.0 0.00055 20.0 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PBP1_TM PF14812.6 EMD00443.1 - 0.024 15.0 5.1 0.024 15.0 5.1 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 EMD00443.1 - 0.36 10.1 2.2 0.53 9.5 2.2 1.2 1 0 0 1 1 1 0 NOA36 protein Efg1 PF10153.9 EMD00444.1 - 5e-36 123.5 1.7 1.1e-35 122.4 1.7 1.6 1 0 0 1 1 1 1 rRNA-processing protein Efg1 Cep57_CLD_2 PF14197.6 EMD00444.1 - 0.43 10.7 9.4 0.26 11.4 3.0 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 zinc_ribbon_16 PF17034.5 EMD00445.1 - 2.9e-20 72.7 6.8 5.7e-20 71.8 6.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EMD00445.1 - 0.0028 17.2 8.7 0.0028 17.2 8.7 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Thioesterase PF00975.20 EMD00446.1 - 0.00044 20.4 2.2 0.22 11.6 0.0 2.6 2 0 0 2 2 2 2 Thioesterase domain PGAP1 PF07819.13 EMD00446.1 - 0.00089 19.0 0.0 0.0026 17.5 0.0 1.7 1 1 1 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 EMD00446.1 - 0.0031 16.8 0.2 0.0079 15.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMD00446.1 - 0.0059 17.2 2.9 0.0059 17.2 2.9 2.3 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMD00446.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Borrelia_P83 PF05262.11 EMD00446.1 - 0.31 9.5 16.8 0.44 9.0 16.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.8 EMD00446.1 - 0.93 9.2 30.5 1.6 8.4 30.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pro_CA PF00484.19 EMD00447.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Carbonic anhydrase Ferric_reduct PF01794.19 EMD00448.1 - 3.7e-18 65.8 12.1 3.7e-18 65.8 12.1 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMD00448.1 - 1.8e-16 60.6 0.0 2e-10 41.0 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMD00448.1 - 1.2e-15 57.5 0.0 8.7e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain adh_short PF00106.25 EMD00450.1 - 6e-25 87.8 0.2 2.8e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMD00450.1 - 6.6e-15 55.3 0.0 1.2e-13 51.1 0.0 2.1 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMD00450.1 - 7.9e-07 29.2 0.1 1.2e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 KR domain ZNRF_3_ecto PF18212.1 EMD00450.1 - 0.16 12.0 0.0 0.81 9.7 0.0 2.0 2 0 0 2 2 2 0 ZNRF-3 Ectodomain Zn_clus PF00172.18 EMD00451.1 - 0.017 15.2 1.2 0.017 15.2 1.2 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.14 EMD00452.1 - 2.5e-08 33.6 0.0 7.3e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Whi5 PF08528.11 EMD00453.1 - 3.3e-06 26.6 0.1 6.1e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Whi5 like Acetyltransf_7 PF13508.7 EMD00454.1 - 9.1e-08 32.4 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EMD00454.1 - 2.4e-07 30.7 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMD00454.1 - 2.3e-06 27.8 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ribonuclease_T2 PF00445.18 EMD00455.1 - 5.3e-43 147.4 0.4 7.9e-43 146.8 0.4 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family TRAM_LAG1_CLN8 PF03798.16 EMD00457.1 - 8.9e-46 156.1 12.3 8.9e-46 156.1 12.3 1.4 2 0 0 2 2 2 1 TLC domain adh_short PF00106.25 EMD00458.1 - 1.3e-21 77.0 0.0 1.6e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EMD00458.1 - 1.8e-12 47.3 0.0 5.6e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMD00458.1 - 6.7e-07 29.4 0.1 9.5e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMD00458.1 - 0.00031 20.3 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EMD00458.1 - 0.0048 16.3 0.0 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EMD00458.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltr_RsmB-F PF01189.17 EMD00459.1 - 3e-35 121.7 0.0 2.7e-28 99.0 0.0 3.3 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Metallophos PF00149.28 EMD00459.1 - 3.5e-11 44.0 0.0 1.1e-10 42.4 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMD00459.1 - 5.5e-10 39.7 0.2 1.2e-08 35.4 0.2 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FtsJ PF01728.19 EMD00459.1 - 0.0017 18.5 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase vATP-synt_AC39 PF01992.16 EMD00461.1 - 9.8e-107 357.3 0.0 1.1e-106 357.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit UL16 PF17622.2 EMD00461.1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Viral unique long protein 16 DUF423 PF04241.15 EMD00461.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF423) ubiquitin PF00240.23 EMD00463.1 - 0.00053 19.7 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 EMD00463.1 - 0.0012 19.4 0.0 0.0019 18.8 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Telomere_res PF16684.5 EMD00463.1 - 0.054 13.0 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Telomere resolvase Presenilin PF01080.17 EMD00463.1 - 3.2 6.4 3.7 2.9 6.5 3.7 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EMD00467.1 - 0.00019 20.3 8.5 0.00019 20.3 8.5 2.1 2 0 0 2 2 2 1 Nucleoporin protein Ndc1-Nup Fungal_trans PF04082.18 EMD00468.1 - 2.3e-27 95.7 0.0 3.8e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD00468.1 - 1.6e-08 34.5 11.7 2.4e-08 33.9 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EMD00469.1 - 7.5e-36 123.8 48.3 1.8e-32 112.7 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMD00469.1 - 4.1e-08 32.5 5.2 4.1e-08 32.5 5.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EMD00469.1 - 0.22 10.3 21.1 0.22 10.4 0.2 3.9 1 1 1 3 3 3 0 MFS_1 like family UQ_con PF00179.26 EMD00472.1 - 1.6e-11 44.0 0.1 2.7e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EMD00472.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Thioredoxin_14 PF18402.1 EMD00473.1 - 0.039 13.9 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain FAD_binding_4 PF01565.23 EMD00474.1 - 8.6e-14 51.5 0.1 9.4e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 EMD00474.1 - 2.9e-07 30.5 0.7 1e-06 28.7 0.6 2.0 2 0 0 2 2 2 1 Berberine and berberine like FAD-oxidase_C PF02913.19 EMD00474.1 - 0.12 12.0 0.0 0.92 9.1 0.0 2.1 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain Acyl-CoA_dh_1 PF00441.24 EMD00475.1 - 5.5e-31 107.8 0.4 9.4e-31 107.0 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EMD00475.1 - 4.1e-22 79.0 0.4 8.1e-22 78.0 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EMD00475.1 - 2.4e-19 69.3 0.0 4.3e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EMD00475.1 - 2.5e-15 56.9 0.4 3.6e-14 53.2 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain tRNA-synt_2b PF00587.25 EMD00476.1 - 5.2e-17 62.4 0.0 1.2e-15 58.0 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EMD00476.1 - 4.6e-09 36.5 0.8 7.6e-09 35.8 0.8 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 EMD00476.1 - 0.043 14.0 2.7 0.067 13.4 2.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ribosomal_S2 PF00318.20 EMD00477.1 - 3.7e-26 91.7 0.3 3.1e-15 56.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EMD00477.1 - 2.9e-08 34.9 8.9 5.9e-08 34.0 8.9 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 EMD00478.1 - 1e-22 80.1 0.0 3.2e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 DUF4850 PF16142.5 EMD00479.1 - 0.04 13.4 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) FixS PF03597.15 EMD00479.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Zn_clus PF00172.18 EMD00480.1 - 2e-07 31.0 9.0 4.8e-07 29.8 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMD00480.1 - 3e-06 26.3 0.8 0.00074 18.4 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Oxidored_molyb PF00174.19 EMD00481.1 - 8.6e-46 155.7 0.0 2.9e-45 154.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EMD00481.1 - 3.4e-21 75.7 2.1 6.9e-21 74.7 2.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.9 EMD00481.1 - 0.13 12.1 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 SLBB domain muHD PF10291.9 EMD00481.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain VASt PF16016.5 EMD00482.1 - 9.7e-22 78.0 0.5 4.6e-21 75.8 0.5 2.2 1 1 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EMD00482.1 - 2.2e-16 60.3 0.1 3.8e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EMD00482.1 - 3e-10 40.6 0.1 8.2e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 PH domain BAR PF03114.18 EMD00482.1 - 0.00081 19.1 0.2 0.0014 18.3 0.2 1.3 1 0 0 1 1 1 1 BAR domain GRAM PF02893.20 EMD00482.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Lebercilin PF15619.6 EMD00482.1 - 0.64 9.7 3.2 0.43 10.2 0.1 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease NmrA PF05368.13 EMD00483.1 - 4.7e-23 82.0 0.1 6.7e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMD00483.1 - 8.8e-20 71.4 0.1 1.4e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMD00483.1 - 0.064 12.7 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family UAA PF08449.11 EMD00485.1 - 3.5e-44 151.2 10.7 4.9e-44 150.8 10.7 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EMD00485.1 - 2.4e-09 37.5 19.0 6e-05 23.2 7.7 3.3 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EMD00485.1 - 2.4e-08 33.5 3.4 0.0002 20.6 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 EMD00485.1 - 0.008 15.2 2.8 0.52 9.2 0.2 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like zf-CCCH PF00642.24 EMD00486.1 - 0.48 10.4 17.7 0.031 14.2 4.2 2.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_S3_C PF00189.20 EMD00487.1 - 4.6e-24 84.7 0.1 2.2e-23 82.5 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EMD00487.1 - 1.4e-09 37.7 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 KH domain Mito_carr PF00153.27 EMD00490.1 - 2.6e-65 216.4 5.2 9e-24 83.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.23 EMD00491.1 - 2.8e-12 46.4 0.1 5.7e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EMD00491.1 - 6e-07 29.3 0.0 6.6e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 MafB19-like deaminase Bd3614-deam PF14439.6 EMD00491.1 - 0.0075 16.3 0.3 0.019 15.0 0.3 1.6 1 1 0 1 1 1 1 Bd3614-like deaminase RecR PF02132.15 EMD00491.1 - 0.0095 15.5 0.1 2.2 7.9 0.1 2.5 2 0 0 2 2 2 2 RecR protein SNAD4 PF18750.1 EMD00491.1 - 0.038 14.1 0.8 0.075 13.2 0.0 1.9 3 0 0 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EMD00491.1 - 0.09 12.8 0.1 0.18 11.9 0.1 1.6 1 1 0 1 1 1 0 APOBEC2 Inv-AAD PF18785.1 EMD00491.1 - 0.1 12.4 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase HTH_30 PF13556.6 EMD00492.1 - 0.19 11.5 0.3 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Cpn60_TCP1 PF00118.24 EMD00493.1 - 2.5e-165 550.8 3.3 2.9e-165 550.6 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ABC2_membrane PF01061.24 EMD00495.1 - 1.3e-82 276.3 52.5 2.3e-43 148.1 16.2 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EMD00495.1 - 5.3e-37 127.4 0.0 5.3e-18 65.9 0.0 2.9 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EMD00495.1 - 1.4e-27 95.4 16.4 4.6e-26 90.6 0.2 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EMD00495.1 - 1.3e-17 64.2 1.4 1.3e-17 64.2 1.4 2.6 2 1 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EMD00495.1 - 1.8e-06 27.9 0.1 0.00032 20.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EMD00495.1 - 8.4e-06 26.3 0.0 0.0012 19.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EMD00495.1 - 1.4e-05 25.0 0.0 0.046 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EMD00495.1 - 3.7e-05 23.8 0.4 0.069 13.2 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EMD00495.1 - 4.7e-05 23.9 0.0 0.0053 17.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EMD00495.1 - 0.00023 21.3 0.0 0.066 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EMD00495.1 - 0.00032 20.4 0.2 0.43 10.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EMD00495.1 - 0.0017 18.6 0.1 0.0064 16.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EMD00495.1 - 0.0043 17.3 0.1 0.4 11.0 0.0 3.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EMD00495.1 - 0.0047 16.5 0.1 0.048 13.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EMD00495.1 - 0.018 14.5 0.8 0.14 11.6 0.0 2.6 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EMD00495.1 - 0.018 14.6 0.1 0.26 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EMD00495.1 - 0.021 14.6 0.4 0.5 10.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain OAD_gamma PF04277.13 EMD00495.1 - 0.029 14.9 0.2 0.11 13.1 0.2 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AAA_30 PF13604.6 EMD00495.1 - 0.045 13.5 1.7 2.7 7.7 0.3 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EMD00495.1 - 0.051 13.5 0.1 0.99 9.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EMD00495.1 - 0.089 12.0 0.2 3.6 6.7 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 EMD00495.1 - 0.13 11.6 0.2 2.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 EMD00495.1 - 0.14 12.1 0.1 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 EMD00495.1 - 0.16 11.2 0.2 0.77 9.0 0.1 1.9 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 EMD00495.1 - 3.9 7.5 5.0 3.3 7.7 0.1 3.2 4 0 0 4 4 4 0 Dynamin family CX9C PF16860.5 EMD00496.1 - 0.00045 20.2 0.5 0.00065 19.7 0.5 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Sfi1 PF08457.10 EMD00497.1 - 1e-159 532.8 110.4 1.4e-159 532.3 96.5 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein FlgT_C PF16538.5 EMD00497.1 - 0.045 14.3 0.5 0.32 11.5 0.0 2.4 3 0 0 3 3 3 0 Flagellar assembly protein T, C-terminal domain Zn_ribbon_17 PF17120.5 EMD00497.1 - 0.2 11.3 1.2 1.4 8.6 0.3 2.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type MutS_III PF05192.18 EMD00497.1 - 0.42 10.8 11.6 0.04 14.1 5.5 2.4 1 1 1 2 2 2 0 MutS domain III DUF3074 PF11274.8 EMD00498.1 - 3.1e-54 183.8 1.4 9.7e-54 182.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 EMD00498.1 - 0.0034 16.8 1.7 0.008 15.6 0.0 2.3 3 0 0 3 3 3 1 START domain RF-1 PF00472.20 EMD00499.1 - 0.006 16.5 3.4 0.013 15.4 3.4 1.6 1 1 0 1 1 1 1 RF-1 domain COesterase PF00135.28 EMD00500.1 - 5.9e-81 272.9 0.2 3.9e-70 237.2 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EMD00500.1 - 1.1e-09 38.5 1.2 1.9e-09 37.7 0.2 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMD00500.1 - 0.39 11.3 7.9 0.65 10.6 6.5 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF4094 PF13334.6 EMD00501.1 - 0.24 11.9 0.1 0.45 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Bac_export_2 PF01312.19 EMD00501.1 - 1.1 8.4 2.4 0.87 8.7 0.1 1.8 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF1270 PF06900.11 EMD00501.1 - 7.1 7.1 12.5 9.5 6.7 0.5 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) DnaJ PF00226.31 EMD00503.1 - 0.0015 18.6 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 EMD00503.1 - 0.0037 17.3 0.0 0.0046 17.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 Protamine_3 PF08188.11 EMD00503.1 - 0.043 14.0 0.3 0.043 14.0 0.3 1.7 2 0 0 2 2 2 0 Spermatozal protamine family P22_AR_C PF10548.9 EMD00504.1 - 0.28 11.4 1.6 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 P22AR C-terminal domain WD40 PF00400.32 EMD00505.1 - 4.6e-24 84.2 10.2 4.7e-06 27.2 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 EMD00505.1 - 4.7e-07 29.6 0.0 1.3e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.6 EMD00505.1 - 6.1e-06 26.0 1.3 0.00022 20.9 1.2 2.6 2 1 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EMD00505.1 - 1.3e-05 25.4 0.3 0.19 12.0 0.0 4.1 2 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMD00505.1 - 6.7e-05 21.7 0.1 0.024 13.3 0.0 3.6 3 1 0 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EMD00505.1 - 0.00013 21.4 0.0 3.5 6.8 0.0 3.9 3 1 1 4 4 4 1 WD40-like domain PQQ PF01011.21 EMD00505.1 - 0.00037 20.3 0.5 0.12 12.4 0.1 3.7 3 0 0 3 3 3 1 PQQ enzyme repeat PEP_mutase PF13714.6 EMD00509.1 - 5.2e-47 160.3 0.2 6.4e-47 160.0 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EMD00509.1 - 7.3e-12 44.5 0.1 1.1e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family BsuBI_PstI_RE PF06616.11 EMD00509.1 - 0.19 11.0 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain HgmA PF04209.13 EMD00510.1 - 9.2e-191 634.1 0.2 1.1e-190 633.9 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_17 PF13431.6 EMD00511.1 - 0.00013 22.1 0.2 0.02 15.2 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Glyoxalase PF00903.25 EMD00512.1 - 1.3e-24 86.8 0.4 5.7e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EMD00512.1 - 2e-13 50.5 0.3 1.2e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EMD00512.1 - 2.1e-06 27.9 0.4 0.00029 21.0 0.4 3.1 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EMD00512.1 - 1.3e-05 25.4 0.4 0.85 9.7 0.0 3.7 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EMD00512.1 - 0.015 16.1 0.3 3.1 8.6 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase-like domain TPR_7 PF13176.6 EMD00512.1 - 0.15 12.2 0.1 20 5.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 EMD00513.1 - 7.6e-29 100.7 25.2 7.6e-29 100.7 25.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PEMT PF04191.13 EMD00513.1 - 0.46 10.9 4.2 0.59 10.6 0.1 2.7 2 0 0 2 2 2 0 Phospholipid methyltransferase Zn_clus PF00172.18 EMD00514.1 - 0.0015 18.6 14.7 0.0025 17.9 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EMD00514.1 - 0.0032 16.5 0.5 2.2 7.2 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain GST_N_2 PF13409.6 EMD00515.1 - 5.6e-12 45.8 0.0 8.6e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EMD00515.1 - 5e-09 36.5 0.0 7.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMD00515.1 - 6.6e-09 36.0 0.1 1e-08 35.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EMD00515.1 - 1.2e-05 25.5 0.0 3e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EMD00515.1 - 0.00025 21.2 0.0 0.00053 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 EMD00515.1 - 0.002 18.3 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EMD00515.1 - 0.036 14.1 0.1 0.19 11.8 0.1 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EMD00515.1 - 0.037 14.3 0.1 0.068 13.5 0.1 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein FAA_hydrolase PF01557.18 EMD00516.1 - 1.8e-50 171.6 0.0 2.7e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EMD00516.1 - 6.9e-22 77.7 0.0 1.3e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAD_binding_3 PF01494.19 EMD00517.1 - 8.5e-11 41.7 0.0 1.6e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EMD00517.1 - 6.4e-05 23.4 0.0 0.0003 21.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 EMD00517.1 - 0.002 17.3 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Pyr_redox_2 PF07992.14 EMD00517.1 - 0.0025 17.1 0.1 0.012 14.9 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMD00517.1 - 0.0074 15.9 0.1 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EMD00517.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EMD00517.1 - 0.04 12.6 0.0 0.12 11.0 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 EMD00517.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMD00517.1 - 0.069 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EMD00517.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EMD00517.1 - 0.19 11.0 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EMD00517.1 - 0.22 10.7 0.0 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1482 PF07358.11 EMD00518.1 - 0.16 11.9 0.1 0.22 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) PLDc_N PF13396.6 EMD00519.1 - 8.3e-12 44.8 8.5 8.3e-12 44.8 8.5 1.5 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal MARVEL PF01284.23 EMD00519.1 - 0.00086 19.4 1.2 0.00097 19.2 1.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF4064 PF13273.6 EMD00519.1 - 0.053 13.8 1.6 0.064 13.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 EMD00519.1 - 0.06 12.1 0.3 0.067 11.9 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1673 PF07895.11 EMD00519.1 - 0.18 11.5 1.8 0.23 11.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Peroxidase_2 PF01328.17 EMD00520.1 - 2e-42 145.8 0.0 3.9e-42 144.9 0.0 1.5 1 0 0 1 1 1 1 Peroxidase, family 2 Thiolase_N PF00108.23 EMD00521.1 - 6.8e-90 300.9 0.5 1.1e-89 300.2 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EMD00521.1 - 4e-37 126.6 1.4 4e-37 126.6 1.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EMD00521.1 - 0.0023 17.7 0.3 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EMD00521.1 - 0.0038 16.9 1.5 0.0038 16.9 1.5 2.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.16 EMD00522.1 - 1.7e-13 50.3 31.9 1.7e-13 50.3 31.9 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily RGS12_usC PF16612.5 EMD00522.1 - 0.28 11.6 13.0 0.081 13.4 4.3 2.6 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 GTP1_OBG PF01018.22 EMD00525.1 - 1.2e-38 132.1 3.1 6.2e-29 100.6 3.9 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EMD00525.1 - 5.4e-23 81.2 0.0 9.6e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMD00525.1 - 4.9e-07 29.4 0.0 1.7e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EMD00525.1 - 0.0047 16.0 0.7 0.33 9.9 0.0 2.5 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EMD00525.1 - 0.029 14.9 0.0 0.057 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EMD00525.1 - 0.062 13.8 0.3 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EMD00525.1 - 0.078 12.5 0.0 8.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EMD00525.1 - 0.16 12.1 0.1 0.43 10.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF3995 PF13160.6 EMD00526.1 - 0.26 11.6 5.4 1 9.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) DUF4131 PF13567.6 EMD00526.1 - 0.35 10.5 3.6 1.3 8.7 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 EMD00526.1 - 1.8 7.3 3.7 6.7 5.4 2.4 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) FtsX PF02687.21 EMD00526.1 - 3.4 8.2 8.2 0.48 10.9 1.5 2.3 2 1 0 2 2 2 0 FtsX-like permease family MgtE PF01769.16 EMD00526.1 - 7.9 6.9 9.3 1.6 9.2 4.9 1.8 1 1 1 2 2 2 0 Divalent cation transporter MFS_1 PF07690.16 EMD00527.1 - 1.3e-26 93.4 72.0 1.6e-24 86.5 47.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.23 EMD00528.1 - 2.5e-116 388.3 0.9 4.9e-116 387.3 0.9 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EMD00528.1 - 2.3e-28 99.0 0.1 7.7e-28 97.3 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding DUF3048 PF11258.8 EMD00528.1 - 0.06 13.4 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) N-terminal domain YojJ PF10372.9 EMD00528.1 - 0.63 10.2 3.8 2.5 8.3 0.9 3.5 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus SlyX PF04102.12 EMD00528.1 - 0.82 10.3 0.0 0.82 10.3 0.0 6.5 7 1 1 8 8 8 0 SlyX Borrelia_REV PF03978.13 EMD00528.1 - 1.1 9.2 6.0 0.29 11.1 1.1 2.6 3 0 0 3 3 3 0 Borrelia burgdorferi REV protein XkdW PF09636.10 EMD00528.1 - 8.1 6.6 13.6 3.3 7.8 1.5 3.3 3 0 0 3 3 3 0 XkdW protein LRR_4 PF12799.7 EMD00530.1 - 2e-10 40.7 8.3 0.2 12.2 0.3 6.8 4 2 3 8 8 8 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EMD00530.1 - 3.8e-10 39.5 1.0 6.6e-10 38.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 EMD00530.1 - 4e-09 35.8 26.5 0.29 11.3 0.1 11.3 13 0 0 13 13 13 3 Leucine Rich repeat F-box PF00646.33 EMD00530.1 - 0.00033 20.5 0.6 0.00033 20.5 0.6 2.9 4 0 0 4 4 4 1 F-box domain DUF1699 PF08004.11 EMD00530.1 - 0.013 15.1 0.2 2.3 7.9 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1699) Cna_B PF05738.13 EMD00531.1 - 0.024 15.1 2.8 0.061 13.9 2.8 1.7 1 0 0 1 1 1 0 Cna protein B-type domain Catalase-rel PF06628.12 EMD00531.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Catalase-related immune-responsive DSPc PF00782.20 EMD00532.1 - 2.2e-24 85.8 0.0 1.2e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EMD00532.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PEP_hydrolase PF09370.10 EMD00537.1 - 1.8e-136 453.6 0.5 2e-136 453.5 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 EMD00537.1 - 0.086 12.2 0.1 0.086 12.2 0.1 1.4 2 0 0 2 2 2 0 Nitronate monooxygenase UPF0261 PF06792.11 EMD00538.1 - 1.8e-161 537.6 0.0 2.1e-161 537.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Ku_PK_bind PF08785.11 EMD00539.1 - 1.1e-27 96.6 0.1 4.4e-27 94.6 0.0 2.2 2 0 0 2 2 2 1 Ku C terminal domain like Ku PF02735.16 EMD00539.1 - 1.7e-27 96.5 0.0 3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EMD00539.1 - 1.4e-13 51.1 0.0 4.1e-13 49.6 0.0 1.8 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 EMD00539.1 - 0.00033 20.9 0.4 0.0027 18.0 0.2 2.3 1 1 1 2 2 2 1 von Willebrand factor type A domain Ank_2 PF12796.7 EMD00540.1 - 4.2e-14 52.9 0.4 2.3e-11 44.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMD00540.1 - 7.7e-10 38.8 0.6 8.2e-06 26.0 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMD00540.1 - 3.2e-09 37.1 0.0 0.0072 16.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMD00540.1 - 1e-08 34.7 0.0 0.00039 20.6 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EMD00540.1 - 0.00024 21.4 0.1 0.95 10.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeat TPR_20 PF14561.6 EMD00540.1 - 0.03 14.6 0.2 0.03 14.6 0.2 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 EMD00541.1 - 1.7e-58 198.1 0.0 2.3e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD00541.1 - 6.3e-19 68.3 0.0 9.7e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMD00541.1 - 9.9e-06 25.1 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EMD00541.1 - 1.9e-05 24.1 0.0 6e-05 22.5 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EMD00541.1 - 0.00028 20.9 0.3 0.36 10.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EMD00541.1 - 0.0035 16.4 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EMD00541.1 - 0.0046 15.8 0.0 0.0073 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EMD00541.1 - 0.0086 15.7 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Abhydrolase_6 PF12697.7 EMD00542.1 - 5.7e-07 30.4 0.1 7.9e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AA_permease_N PF08403.10 EMD00542.1 - 0.076 12.5 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF3074 PF11274.8 EMD00543.1 - 7.1e-45 153.3 0.6 1e-44 152.7 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) OST3_OST6 PF04756.13 EMD00544.1 - 0.18 11.2 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Rotamase_3 PF13616.6 EMD00545.1 - 1.5e-15 57.8 0.1 3.2e-15 56.7 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EMD00545.1 - 1.8e-14 54.5 0.0 3e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EMD00545.1 - 1.4e-05 25.9 0.0 1.9e-05 25.5 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain HET PF06985.11 EMD00546.1 - 4.1e-20 72.6 0.0 4.9e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 EMD00547.1 - 9.5e-10 38.1 8.1 2.2e-09 37.0 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 EMD00547.1 - 0.51 10.7 7.4 1.2 9.5 7.4 1.6 1 0 0 1 1 1 0 C1 domain Scs3p PF10261.9 EMD00549.1 - 4.4e-77 258.9 0.5 5.4e-77 258.6 0.5 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM MFS_1 PF07690.16 EMD00550.1 - 5.4e-22 78.2 34.0 5.4e-22 78.2 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SWIB PF02201.18 EMD00551.1 - 1.5e-23 82.5 0.0 3.3e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Hid1 PF12722.7 EMD00552.1 - 0.77 7.8 1.2 0.98 7.5 1.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.10 EMD00552.1 - 2.5 7.4 9.0 0.47 9.8 5.4 1.5 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Glyco_hydro_72 PF03198.14 EMD00553.1 - 3.9e-99 331.9 0.0 5.3e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Pkinase PF00069.25 EMD00554.1 - 3.3e-64 216.8 0.0 4.3e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD00554.1 - 5e-30 104.6 0.0 7.3e-29 100.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMD00554.1 - 0.0001 21.7 0.2 0.0079 15.5 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EMD00554.1 - 0.0047 15.9 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMD00554.1 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EMD00554.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EMD00554.1 - 0.081 12.5 0.1 10 5.6 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Arylsulfotran_2 PF14269.6 EMD00555.1 - 1.8e-46 158.9 2.1 2.6e-46 158.4 2.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.16 EMD00555.1 - 1.2e-23 83.6 46.7 1.4e-23 83.4 5.3 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Arylsulfotrans PF05935.11 EMD00555.1 - 4.7e-14 52.1 0.4 6e-13 48.4 0.4 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfotransfer_4 PF17784.1 EMD00556.1 - 8.7e-71 238.2 0.1 1.1e-70 237.9 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMD00556.1 - 1.7e-05 25.3 0.2 0.0013 19.1 0.1 2.3 1 1 1 2 2 2 2 Sulfotransferase family AhpC-TSA PF00578.21 EMD00559.1 - 3.6e-30 104.4 0.0 5.2e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EMD00559.1 - 6.2e-15 55.2 0.0 8e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EMD00559.1 - 3.6e-13 49.1 0.1 6.5e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Fungal_trans_2 PF11951.8 EMD00560.1 - 2e-07 30.2 0.4 3.4e-06 26.1 0.0 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD00560.1 - 2.6e-07 30.6 11.0 4.5e-07 29.9 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.12 EMD00560.1 - 0.48 9.1 1.9 0.94 8.1 1.9 1.4 1 0 0 1 1 1 0 Per os infectivity Ribosomal_L15e PF00827.17 EMD00561.1 - 4.9e-90 300.4 9.7 5.9e-90 300.1 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 HECT PF00632.25 EMD00562.1 - 3.3e-72 243.6 0.0 4.5e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) OrfB_Zn_ribbon PF07282.11 EMD00562.1 - 0.15 12.0 0.6 0.39 10.7 0.6 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain F-box-like PF12937.7 EMD00563.1 - 3.1e-07 30.2 2.1 3.1e-07 30.2 2.1 2.3 2 0 0 2 2 2 1 F-box-like RabGAP-TBC PF00566.18 EMD00564.1 - 3.8e-38 131.3 0.1 6e-38 130.7 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NT-C2 PF10358.9 EMD00565.1 - 1e-30 106.4 0.0 1.3e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins MFS_1 PF07690.16 EMD00566.1 - 5.7e-16 58.4 62.5 1.1e-13 50.9 56.0 3.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EMD00566.1 - 2.1e-12 46.3 24.5 3.3e-12 45.6 24.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EMD00566.1 - 1.4e-05 24.2 15.9 1.4e-05 24.2 15.9 3.4 3 1 0 3 3 3 1 Sugar (and other) transporter Pox_A14 PF05767.12 EMD00566.1 - 0.41 10.8 5.7 0.13 12.4 1.4 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Glyco_transf_8 PF01501.20 EMD00567.1 - 1.7e-22 80.2 0.0 1.4e-21 77.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EMD00567.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 EMD00567.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase IU_nuc_hydro PF01156.19 EMD00571.1 - 7.8e-80 268.7 0.0 9.7e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Adaptin_N PF01602.20 EMD00572.1 - 1.1e-138 463.1 0.4 1.3e-138 462.9 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EMD00572.1 - 8.7e-23 80.8 0.0 2.5e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EMD00572.1 - 2.2e-08 34.3 3.0 0.00038 20.5 0.0 4.1 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMD00572.1 - 3.1e-05 24.3 0.7 2.3 8.7 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EMD00572.1 - 0.0032 17.6 2.7 20 5.8 0.1 4.4 4 0 0 4 4 4 2 HEAT repeat PTS_2-RNA PF01885.16 EMD00573.1 - 7.5e-68 228.1 0.0 8.6e-68 227.9 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family MMR_HSR1_Xtn PF16897.5 EMD00574.1 - 4.7e-40 135.9 1.8 8.5e-40 135.1 1.0 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EMD00574.1 - 3.6e-23 81.4 0.1 7.4e-23 80.4 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EMD00574.1 - 1.1e-20 73.8 0.1 5e-20 71.7 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMD00574.1 - 3.9e-09 36.2 0.1 2.3e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EMD00574.1 - 0.00073 19.6 0.1 0.18 11.9 0.0 2.6 2 1 0 2 2 2 2 Dynamin family MeaB PF03308.16 EMD00574.1 - 0.01 14.8 0.8 0.02 13.9 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EMD00574.1 - 0.096 12.6 1.4 3.7 7.4 0.1 3.1 2 1 1 3 3 3 0 RsgA GTPase Response_reg PF00072.24 EMD00575.1 - 7e-23 80.9 0.2 3.4e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EMD00575.1 - 6.5e-21 74.9 0.0 1.6e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 EMD00575.1 - 3.6e-08 33.6 0.1 5.9e-05 23.3 0.0 3.5 2 1 0 2 2 2 2 PAS fold HisKA PF00512.25 EMD00575.1 - 6.1e-06 26.2 0.6 2.8e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EMD00575.1 - 4e-05 23.8 0.0 0.017 15.4 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EMD00575.1 - 8.4e-05 22.5 0.0 0.00084 19.3 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EMD00575.1 - 0.00075 19.7 0.0 0.7 10.2 0.0 4.0 3 2 0 3 3 3 1 PAS fold PAS_8 PF13188.7 EMD00575.1 - 0.031 14.3 0.0 4 7.6 0.0 2.9 2 0 0 2 2 2 0 PAS domain Glyco_hydro_39 PF01229.17 EMD00575.1 - 0.11 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 CDO_I PF05995.12 EMD00576.1 - 6.2e-40 136.3 0.1 2e-38 131.4 0.1 2.1 1 1 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EMD00576.1 - 0.00013 21.5 1.2 0.00029 20.3 1.2 1.6 1 1 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 EMD00576.1 - 0.031 14.0 0.0 7.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Cupin domain PXA PF02194.15 EMD00577.1 - 2e-39 135.4 0.6 3e-39 134.9 0.6 1.3 1 0 0 1 1 1 1 PXA domain HTH_Tnp_Tc5 PF03221.16 EMD00578.1 - 5e-15 55.3 0.0 8.9e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EMD00578.1 - 3.5e-06 26.6 0.1 6.9e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_4 PF13613.6 EMD00578.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 EMD00578.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 EMD00578.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Aminotran_1_2 PF00155.21 EMD00580.1 - 2.2e-69 234.4 0.0 2.5e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EMD00580.1 - 0.00069 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EMD00580.1 - 0.0035 16.4 0.0 0.011 14.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EMD00580.1 - 0.0061 15.1 0.1 0.017 13.7 0.1 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EMD00580.1 - 0.04 13.2 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase EB1 PF03271.17 EMD00581.1 - 3.1e-17 62.5 0.9 6.7e-17 61.5 0.9 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EMD00581.1 - 5.6e-07 29.7 0.1 1.2e-06 28.6 0.1 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Syja_N PF02383.18 EMD00581.1 - 0.068 12.5 0.0 0.069 12.4 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Herpes_UL6 PF01763.16 EMD00581.1 - 0.15 10.6 0.0 0.27 9.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like MFS_5 PF05631.14 EMD00582.1 - 6.9e-69 232.4 12.4 1.6e-68 231.3 12.4 1.5 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EMD00582.1 - 3.3e-20 72.3 28.2 4.8e-20 71.8 28.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EMD00582.1 - 0.0028 16.6 6.9 0.033 13.0 6.9 2.5 1 1 0 1 1 1 1 MFS_1 like family DUF3431 PF11913.8 EMD00583.1 - 0.00081 19.2 0.1 0.0018 18.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) Methyltransf_24 PF13578.6 EMD00584.1 - 1.5e-06 29.2 0.0 7.1e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Peripla_BP_2 PF01497.18 EMD00584.1 - 0.053 13.1 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein H_lectin PF09458.10 EMD00585.1 - 1.9e-48 162.5 0.0 5.9e-18 64.8 0.0 3.2 3 0 0 3 3 3 3 H-type lectin domain FAD_binding_7 PF03441.14 EMD00586.1 - 2.1e-73 246.1 0.3 3.3e-73 245.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EMD00586.1 - 1.3e-35 122.9 0.0 2.2e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase DUF2149 PF09919.9 EMD00586.1 - 0.24 11.7 0.0 0.47 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Sen15 PF09631.10 EMD00587.1 - 4.2e-23 81.5 0.0 5.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein DUF2985 PF11204.8 EMD00588.1 - 2.6e-38 130.0 3.6 4.8e-38 129.2 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Pkinase PF00069.25 EMD00592.1 - 3.9e-63 213.3 0.0 4.7e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD00592.1 - 1.5e-33 116.2 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMD00592.1 - 2.6e-07 30.3 0.0 4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EMD00592.1 - 0.0001 21.2 0.0 0.00015 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EMD00592.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EMD00592.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EMD00592.1 - 0.21 11.2 0.0 1.7 8.2 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DARPP-32 PF05395.12 EMD00593.1 - 0.045 14.0 5.7 0.11 12.7 5.7 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 HEAT PF02985.22 EMD00595.1 - 0.99 9.8 6.0 2.2 8.8 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat Chalcone_2 PF16035.5 EMD00596.1 - 4.6e-69 232.3 0.0 6.5e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EMD00596.1 - 0.00011 22.3 0.0 0.00034 20.8 0.0 1.7 2 0 0 2 2 2 1 Chalcone isomerase-like Arginase PF00491.21 EMD00598.1 - 1.3e-24 87.1 0.7 1.6e-24 86.9 0.7 1.0 1 0 0 1 1 1 1 Arginase family MBOAT PF03062.19 EMD00600.1 - 3.4e-37 128.6 23.4 2.1e-36 126.0 23.3 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Herpes_UL49_5 PF05702.11 EMD00600.1 - 0.015 15.4 3.0 0.23 11.6 0.6 2.8 2 1 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein DUF2967 PF11179.8 EMD00600.1 - 0.7 7.9 2.6 0.95 7.5 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Cytochrom_B_C PF00032.17 EMD00600.1 - 0.99 9.7 8.8 6.8 7.0 0.4 3.2 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Aminopep PF10023.9 EMD00602.1 - 0.05 13.0 0.0 0.056 12.8 0.0 1.0 1 0 0 1 1 1 0 Putative aminopeptidase Peptidase_M28 PF04389.17 EMD00603.1 - 6.3e-37 127.2 0.0 1.4e-36 126.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EMD00603.1 - 0.00023 20.9 1.3 0.00046 20.0 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Sec39 PF08314.11 EMD00604.1 - 9.8e-276 917.0 0.0 1.2e-275 916.7 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Abhydrolase_4 PF08386.10 EMD00605.1 - 3.8e-21 75.1 0.0 7.7e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EMD00605.1 - 7.4e-19 68.4 0.1 3.1e-08 33.6 0.0 3.4 3 1 1 4 4 4 3 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMD00605.1 - 0.014 14.9 0.0 6.1 6.3 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family SnoaL_2 PF12680.7 EMD00606.1 - 0.0018 18.9 0.0 0.0025 18.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain PCuAC PF04314.13 EMD00606.1 - 0.06 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Copper chaperone PCu(A)C SLAC1 PF03595.17 EMD00607.1 - 1.9e-62 211.4 55.1 2.1e-62 211.3 55.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DHDPS PF00701.22 EMD00610.1 - 2.4e-29 102.0 0.1 2.8e-29 101.7 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 EMD00611.1 - 1.1e-08 35.9 0.5 3.5e-08 34.3 0.5 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold BTB PF00651.31 EMD00612.1 - 0.048 13.9 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain PIG-H PF10181.9 EMD00613.1 - 1.4e-26 92.1 1.4 2.5e-26 91.3 1.4 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component BatA PF07584.11 EMD00613.1 - 0.056 13.8 1.0 0.056 13.8 1.0 2.1 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal PseudoU_synth_1 PF01416.20 EMD00614.1 - 2.1e-32 111.8 0.0 8.4e-31 106.6 0.0 2.8 3 0 0 3 3 3 1 tRNA pseudouridine synthase NmrA PF05368.13 EMD00615.1 - 9.3e-15 54.8 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMD00615.1 - 6.1e-11 42.6 0.1 1.7e-10 41.1 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GFO_IDH_MocA PF01408.22 EMD00615.1 - 0.00043 21.1 0.0 0.001 19.9 0.1 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.21 EMD00615.1 - 0.00071 19.1 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EMD00615.1 - 0.0068 16.8 0.1 0.012 16.0 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 EMD00615.1 - 0.019 15.6 0.2 0.036 14.7 0.2 1.4 1 0 0 1 1 1 0 CoA binding domain Ldh_1_N PF00056.23 EMD00615.1 - 0.064 13.4 0.5 0.19 11.9 0.5 1.8 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.20 EMD00615.1 - 0.089 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 EMD00615.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family His_Phos_1 PF00300.22 EMD00616.1 - 5.9e-05 22.9 4.2 4.6 6.9 0.3 4.2 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Sulfotransfer_4 PF17784.1 EMD00617.1 - 8.6e-18 65.0 0.0 9.9e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain LigB PF02900.18 EMD00617.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase zf-C2H2_jaz PF12171.8 EMD00618.1 - 1.2e-09 38.2 0.5 1.9e-09 37.5 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EMD00618.1 - 3.8e-07 30.3 0.5 7.3e-07 29.4 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 EMD00618.1 - 0.031 14.4 0.1 0.056 13.6 0.1 1.3 1 0 0 1 1 1 0 DBF zinc finger OrsD PF12013.8 EMD00618.1 - 0.084 13.3 0.2 4.3 7.8 0.1 2.3 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 EMD00618.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Fzo_mitofusin PF04799.13 EMD00618.1 - 0.12 12.0 1.7 0.2 11.2 1.7 1.3 1 0 0 1 1 1 0 fzo-like conserved region zf-C2H2 PF00096.26 EMD00618.1 - 0.17 12.4 0.5 0.29 11.7 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DNA_topoisoIV PF00521.20 EMD00619.1 - 7.9e-130 433.6 0.1 3.1e-129 431.6 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EMD00619.1 - 1.7e-48 164.1 0.5 6e-48 162.3 0.5 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EMD00619.1 - 5e-27 94.5 4.5 1.2e-26 93.2 4.5 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EMD00619.1 - 1e-11 45.3 0.0 2.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EMD00619.1 - 3.6e-07 30.4 0.0 2.3e-06 27.8 0.0 2.5 1 0 0 1 1 1 1 Toprim domain AcylCoA_dehyd_C PF12186.8 EMD00619.1 - 0.17 12.0 1.1 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal E1-E2_ATPase PF00122.20 EMD00620.1 - 4.4e-35 120.8 12.0 1.9e-30 105.7 0.5 3.5 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMD00620.1 - 4.8e-26 91.6 5.7 4.8e-26 91.6 5.7 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMD00620.1 - 4.2e-19 69.7 0.1 2e-17 64.2 0.1 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMD00620.1 - 3.8e-18 65.4 0.0 7.9e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMD00620.1 - 9.1e-13 47.7 0.2 3e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMD00620.1 - 4.7e-05 23.3 0.6 0.00063 19.6 0.3 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2269 PF10027.9 EMD00620.1 - 0.0091 16.1 1.7 0.028 14.5 1.7 1.8 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) CoA_binding_3 PF13727.6 EMD00620.1 - 0.38 10.8 8.3 0.088 12.8 3.5 2.4 2 0 0 2 2 2 0 CoA-binding domain Na_Pi_cotrans PF02690.15 EMD00620.1 - 1.9 8.6 8.6 0.14 12.3 2.8 2.1 2 0 0 2 2 2 0 Na+/Pi-cotransporter Fungal_trans PF04082.18 EMD00621.1 - 1.7e-30 105.9 0.0 2.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD00621.1 - 1.4e-09 37.9 10.9 2.2e-09 37.3 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EMD00623.1 - 2.3e-21 76.1 35.3 1.2e-20 73.8 31.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PX PF00787.24 EMD00624.1 - 8.4e-15 54.7 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 PX domain T3SS_HrpK1 PF16937.5 EMD00624.1 - 0.03 14.0 0.9 0.066 12.9 0.4 1.7 1 1 1 2 2 2 0 Type III secretion system translocator protein, HrpF DUF733 PF05306.11 EMD00624.1 - 0.05 13.9 0.2 0.13 12.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF733) PHD PF00628.29 EMD00625.1 - 3.3e-06 26.9 7.0 5.5e-06 26.2 7.0 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 EMD00625.1 - 0.062 13.9 0.4 0.11 13.1 0.4 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding BATS PF06968.13 EMD00626.1 - 2.8e-21 75.4 0.5 1.1e-20 73.5 0.0 2.3 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EMD00626.1 - 4.2e-13 50.0 0.3 4.2e-12 46.7 0.0 2.7 4 0 0 4 4 4 1 Radical SAM superfamily A_deamin PF02137.18 EMD00627.1 - 9.3e-26 91.0 0.0 5e-25 88.7 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain GTP_EFTU PF00009.27 EMD00628.1 - 3e-55 186.8 0.1 4.7e-55 186.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EMD00628.1 - 1.1e-41 141.7 0.0 2.2e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EMD00628.1 - 2.5e-13 50.2 2.2 2.5e-13 50.2 2.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EMD00628.1 - 0.00069 19.7 0.1 0.016 15.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SLS PF14611.6 EMD00630.1 - 1.2e-20 74.3 0.3 2.1e-20 73.5 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Amelogenin PF02948.15 EMD00630.1 - 0.12 13.0 0.1 2.2 8.9 0.0 2.6 3 0 0 3 3 3 0 Amelogenin MoeA_N PF03453.17 EMD00632.1 - 6.2e-23 81.3 0.1 1.1e-22 80.5 0.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EMD00632.1 - 5.4e-17 61.8 0.0 9.6e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 EMD00632.1 - 0.036 14.3 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) DUF3818 PF12825.7 EMD00634.1 - 9e-50 169.6 0.0 1.2e-28 100.2 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EMD00634.1 - 2.9e-37 127.5 0.0 1e-36 125.8 0.0 1.9 2 0 0 2 2 2 1 PX-associated Metal_resist PF13801.6 EMD00634.1 - 0.022 15.0 0.2 0.13 12.5 0.2 2.1 2 0 0 2 2 2 0 Heavy-metal resistance DUF1517 PF07466.11 EMD00634.1 - 0.074 13.2 0.1 0.25 11.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Carb_bind PF10645.9 EMD00635.1 - 4.2e-19 68.5 10.9 8.5e-19 67.5 10.9 1.6 1 0 0 1 1 1 1 Carbohydrate binding Abhydrolase_3 PF07859.13 EMD00636.1 - 1e-48 166.0 0.0 1.3e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EMD00636.1 - 2.8e-05 23.2 0.2 5.8e-05 22.1 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EMD00636.1 - 0.0031 17.0 0.0 0.058 12.9 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EMD00636.1 - 0.014 14.7 0.1 0.026 13.8 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 EMD00636.1 - 0.017 14.0 0.0 0.04 12.8 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase AXE1 PF05448.12 EMD00636.1 - 0.063 11.9 0.4 0.11 11.1 0.4 1.5 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 EMD00636.1 - 0.069 12.6 0.8 0.12 11.8 0.8 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase ERM PF00769.19 EMD00637.1 - 5e-05 23.3 31.3 7.1e-05 22.8 31.3 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Asp-B-Hydro_N PF05279.11 EMD00637.1 - 5 7.1 30.0 7.6 6.5 30.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.9 EMD00637.1 - 5.2 5.8 37.4 7.5 5.3 37.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1772 PF08592.11 EMD00638.1 - 1.1e-24 87.3 1.3 1.5e-24 86.9 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2633 PF11119.8 EMD00638.1 - 0.22 11.5 1.6 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) ERG4_ERG24 PF01222.17 EMD00640.1 - 1.3e-157 525.0 6.9 1.6e-157 524.7 6.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EMD00640.1 - 6.8e-05 22.5 0.4 0.00015 21.3 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4244 PF14029.6 EMD00640.1 - 0.076 12.5 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) DUF829 PF05705.14 EMD00641.1 - 1.4e-48 166.0 0.0 1.7e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DctQ PF04290.12 EMD00641.1 - 0.011 15.7 0.6 0.02 14.8 0.3 1.6 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component EMP70 PF02990.16 EMD00642.1 - 0.0012 17.6 2.6 0.0013 17.5 2.6 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 CorA PF01544.18 EMD00642.1 - 0.016 14.5 5.8 0.018 14.4 5.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GMC_oxred_C PF05199.13 EMD00644.1 - 5.2e-30 104.9 0.0 1e-29 103.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EMD00644.1 - 7.4e-27 94.5 0.0 2.4e-23 83.0 0.0 2.7 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 EMD00644.1 - 4.5e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EMD00644.1 - 6.1e-05 22.3 0.0 0.00013 21.2 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EMD00644.1 - 0.0081 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EMD00644.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 ThiF family Guanylate_kin PF00625.21 EMD00644.1 - 0.21 11.2 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase Arylsulfotran_2 PF14269.6 EMD00645.1 - 2.7e-42 145.2 0.3 5.8e-42 144.1 0.3 1.6 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EMD00645.1 - 7.9e-10 38.2 0.5 1.8e-09 37.0 0.5 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Abhydrolase_1 PF00561.20 EMD00646.1 - 5.7e-23 81.9 0.0 3.6e-21 76.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMD00646.1 - 1.8e-15 56.9 0.1 2.4e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMD00646.1 - 1.6e-13 51.8 1.0 1.9e-13 51.5 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EMD00646.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Tannase PF07519.11 EMD00646.1 - 0.032 13.2 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase PGAP1 PF07819.13 EMD00646.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.11 EMD00646.1 - 0.09 12.7 0.1 0.24 11.3 0.0 1.7 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 EMD00646.1 - 0.16 11.6 0.0 0.65 9.6 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) VKG_Carbox PF05090.14 EMD00647.1 - 0.00088 18.2 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Caveolin PF01146.17 EMD00647.1 - 0.12 12.3 0.3 0.19 11.7 0.3 1.3 1 0 0 1 1 1 0 Caveolin Aminotran_1_2 PF00155.21 EMD00649.1 - 7.6e-59 199.7 0.0 9e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EMD00649.1 - 0.0083 14.7 0.0 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 EMD00649.1 - 0.043 12.7 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 Allinase CTP_transf_1 PF01148.20 EMD00650.1 - 0.00073 19.4 2.4 0.0012 18.7 2.4 1.3 1 1 0 1 1 1 1 Cytidylyltransferase family Arg_repressor_C PF02863.18 EMD00650.1 - 0.2 11.5 0.1 0.38 10.6 0.1 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain UQ_con PF00179.26 EMD00651.1 - 1.5e-51 173.7 0.0 1.7e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EMD00651.1 - 0.0015 18.3 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EMD00651.1 - 0.077 13.3 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 RWD domain Peptidase_C1_2 PF03051.15 EMD00653.1 - 1.3e-156 521.8 0.0 1.5e-156 521.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EMD00653.1 - 5.8e-07 29.8 0.0 0.014 15.5 0.0 2.5 3 0 0 3 3 3 2 Papain family cysteine protease ALIX_LYPXL_bnd PF13949.6 EMD00653.1 - 0.035 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV CmcI PF04989.12 EMD00655.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase PS-DH PF14765.6 EMD00656.1 - 1.2e-13 51.0 0.0 2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_16 PF10294.9 EMD00657.1 - 4.4e-13 49.3 0.0 6.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DUF2543 PF10820.8 EMD00657.1 - 0.1 12.8 0.1 5.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) DnaJ PF00226.31 EMD00658.1 - 5.2e-21 74.5 0.7 5.8e-21 74.4 0.7 1.0 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 EMD00660.1 - 1e-10 42.4 0.1 1.6e-10 41.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMD00660.1 - 3.8e-06 27.2 0.0 0.00012 22.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MR_MLE_C PF13378.6 EMD00661.1 - 2.4e-57 194.1 0.0 3.2e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EMD00661.1 - 1.5e-16 60.7 0.0 3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain ADH_zinc_N PF00107.26 EMD00662.1 - 2.1e-26 92.4 0.0 5.3e-26 91.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EMD00662.1 - 2.8e-20 73.7 0.0 1e-19 71.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EMD00662.1 - 1.2e-07 31.6 0.1 2.7e-07 30.4 0.1 1.6 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 EMD00662.1 - 1.3e-05 25.0 0.1 3e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sod_Fe_C PF02777.18 EMD00663.1 - 1.9e-40 137.2 0.2 5e-40 135.8 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EMD00663.1 - 2.6e-31 107.9 0.8 4.7e-31 107.1 0.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MFS_1 PF07690.16 EMD00664.1 - 2.4e-33 115.5 21.1 3.4e-33 115.0 21.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMD00664.1 - 7.9e-13 48.1 10.0 7.9e-13 48.1 10.0 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EMD00664.1 - 0.00013 20.6 4.3 0.00013 20.6 4.3 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EMD00664.1 - 0.0035 15.8 7.2 0.33 9.3 0.2 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Cellulase PF00150.18 EMD00666.1 - 2e-09 37.3 0.0 5.7e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Cation_ATPase_N PF00690.26 EMD00668.1 - 0.13 12.0 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Peptidase_C13 PF01650.18 EMD00673.1 - 9.7e-40 136.7 0.1 4.9e-24 85.2 0.1 2.1 1 1 0 2 2 2 2 Peptidase C13 family RabGAP-TBC PF00566.18 EMD00675.1 - 1.1e-51 175.6 0.0 1.9e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain OPT PF03169.15 EMD00677.1 - 9.8e-149 496.8 14.3 1.1e-148 496.6 14.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2198 PF09964.9 EMD00677.1 - 0.31 11.2 4.1 11 6.2 0.5 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Ccdc124 PF06244.12 EMD00678.1 - 5.2e-26 91.7 21.6 6.7e-25 88.1 21.6 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 GREB1 PF15782.5 EMD00678.1 - 6 3.8 5.7 7 3.6 5.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Patatin PF01734.22 EMD00681.1 - 2.6e-14 53.9 0.6 1.1e-13 51.8 0.6 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase MMR_HSR1 PF01926.23 EMD00681.1 - 0.0022 18.0 0.0 0.0047 17.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-RING_UBOX PF13445.6 EMD00681.1 - 0.013 15.5 11.0 0.037 14.1 11.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EMD00681.1 - 0.29 11.3 9.8 1.2 9.4 9.9 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EMD00681.1 - 1 9.3 8.6 3.2 7.8 8.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EMD00681.1 - 2 8.8 17.2 0.093 13.1 11.5 1.8 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 EMD00681.1 - 6 6.8 9.9 15 5.5 9.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EMD00681.1 - 7.9 6.5 17.5 0.12 12.3 10.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_4 PF07721.14 EMD00683.1 - 0.013 16.0 3.0 0.45 11.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EMD00683.1 - 0.04 14.6 0.2 9.4 7.1 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EMD00683.1 - 6.7 7.8 6.4 14 6.8 0.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 EMD00684.1 - 3.6e-40 132.5 18.9 0.025 14.8 0.0 13.4 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 EMD00684.1 - 5.4e-37 126.1 8.0 2e-10 40.9 0.0 8.5 3 1 7 10 10 10 9 HEAT repeats Cnd1 PF12717.7 EMD00684.1 - 1.7e-13 51.0 10.5 6.9e-05 22.9 0.2 6.6 5 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EMD00684.1 - 7.6e-12 45.5 12.8 0.14 12.7 0.1 9.4 8 2 2 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EMD00684.1 - 6.7e-11 42.6 0.3 0.00047 20.7 0.1 6.7 6 2 3 9 9 9 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EMD00684.1 - 3.1e-08 32.6 10.3 0.00095 17.8 2.2 5.6 3 1 0 4 4 4 3 Adaptin N terminal region RTP1_C1 PF10363.9 EMD00684.1 - 3.4e-06 27.2 4.8 0.37 11.0 0.2 4.9 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EMD00684.1 - 4.5e-06 26.4 1.5 0.35 10.4 0.0 4.7 3 2 1 4 4 4 2 CLASP N terminal Arm PF00514.23 EMD00684.1 - 0.0022 18.0 4.3 2.8 8.1 0.0 5.9 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 EMD00684.1 - 0.034 12.7 1.7 0.75 8.2 0.1 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit IFRD PF05004.13 EMD00684.1 - 0.056 12.6 0.1 3.3 6.7 0.0 3.1 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) API5 PF05918.11 EMD00684.1 - 2.5 6.8 5.5 5.9 5.6 0.5 3.4 3 2 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) tRNA_synthFbeta PF17759.1 EMD00685.1 - 1.9e-44 151.7 0.0 2.9e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EMD00685.1 - 3.9e-32 110.3 0.1 9.2e-32 109.1 0.0 1.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EMD00685.1 - 4.3e-24 85.1 0.1 7e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EMD00685.1 - 1e-15 57.8 0.0 3.5e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Forkhead PF00250.18 EMD00686.1 - 2e-32 111.3 0.1 3.8e-32 110.4 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EMD00686.1 - 4.4e-09 36.6 0.0 8.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 EMD00686.1 - 0.015 15.5 0.0 0.044 14.0 0.0 1.7 2 0 0 2 2 2 0 FHA domain Yop-YscD_cpl PF16697.5 EMD00686.1 - 0.082 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain PGA_cap PF09587.10 EMD00688.1 - 3.8e-68 229.7 0.1 4.9e-68 229.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Glyco_transf_4 PF13439.6 EMD00688.1 - 0.087 12.8 0.4 0.087 12.8 0.4 2.4 2 2 0 3 3 3 0 Glycosyltransferase Family 4 LRR_6 PF13516.6 EMD00689.1 - 6.3e-11 41.4 14.9 0.0068 16.4 0.1 7.2 8 0 0 8 8 8 3 Leucine Rich repeat F-box-like PF12937.7 EMD00689.1 - 6.8e-09 35.5 0.3 1.7e-08 34.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMD00689.1 - 2.2e-08 33.8 0.3 1.2e-07 31.5 0.2 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 EMD00689.1 - 1.2e-06 28.7 10.6 0.027 14.9 0.3 5.5 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EMD00689.1 - 0.0045 17.3 18.0 1.1 10.1 0.0 6.3 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 EMD00689.1 - 3.4 7.5 5.3 72 3.3 0.0 4.7 5 1 0 5 5 5 0 Leucine rich repeat Abhydrolase_1 PF00561.20 EMD00690.1 - 9.1e-10 38.6 1.5 1.4e-09 38.0 1.5 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMD00690.1 - 5.5e-08 33.7 3.9 6.9e-08 33.4 3.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMD00690.1 - 0.0048 16.2 0.1 0.0069 15.7 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1295 PF06966.12 EMD00691.1 - 1.7e-41 142.3 6.4 2e-41 142.1 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Abhydrolase_6 PF12697.7 EMD00692.1 - 1.4e-10 42.1 4.9 1.8e-10 41.8 4.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMD00692.1 - 1.8e-06 27.8 0.1 2.6e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMD00692.1 - 0.00057 19.2 0.1 0.00084 18.7 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LMBR1 PF04791.16 EMD00693.1 - 1e-115 387.6 2.3 1.2e-115 387.3 2.3 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein HemX PF04375.14 EMD00693.1 - 0.019 14.3 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Laminin_II PF06009.12 EMD00693.1 - 0.16 12.0 0.2 6.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 EMD00693.1 - 0.59 10.6 2.1 0.68 10.4 0.8 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fungal_trans_2 PF11951.8 EMD00694.1 - 5.3e-05 22.2 0.9 7.1e-05 21.8 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Topoisom_bac PF01131.20 EMD00695.1 - 1e-99 334.4 0.0 3.7e-93 312.8 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 EMD00695.1 - 2.5e-19 69.4 0.0 5.6e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DEAD PF00270.29 EMD00697.1 - 2.6e-42 144.6 0.0 6.5e-42 143.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMD00697.1 - 5.2e-30 104.0 0.0 1.2e-29 102.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMD00697.1 - 0.0017 18.4 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EMD00697.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 EMD00697.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Hydrolase_like PF13242.6 EMD00697.1 - 0.24 11.5 1.0 0.88 9.7 0.1 2.4 3 0 0 3 3 3 0 HAD-hyrolase-like CHORD PF04968.12 EMD00698.1 - 1.5e-44 150.5 22.9 5.8e-25 87.8 6.9 3.1 2 1 0 2 2 2 2 CHORD CS PF04969.16 EMD00698.1 - 5.7e-11 43.3 0.2 1.1e-10 42.4 0.2 1.5 1 0 0 1 1 1 1 CS domain HET PF06985.11 EMD00700.1 - 2.7e-27 95.9 0.0 3.7e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EMD00701.1 - 5.7e-30 103.7 0.0 4.4e-11 43.2 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMD00701.1 - 1.2e-27 92.8 0.1 9e-05 22.6 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 EMD00701.1 - 3.6e-26 90.4 0.2 8.1e-06 26.1 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EMD00701.1 - 1.6e-25 89.1 0.0 1.9e-08 34.7 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EMD00701.1 - 4e-25 87.5 0.1 6.9e-10 39.0 0.0 3.6 1 1 2 4 4 4 4 Ankyrin repeats (many copies) NARP1 PF12569.8 EMD00702.1 - 2.1e-181 604.3 16.2 2.1e-181 604.3 16.2 2.8 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 EMD00702.1 - 9.8e-19 67.6 20.1 0.00026 21.4 0.6 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EMD00702.1 - 8.3e-18 64.8 30.7 0.00015 22.4 1.0 9.5 8 1 2 10 10 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 EMD00702.1 - 3.2e-14 52.1 25.3 4.6e-06 26.2 0.3 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EMD00702.1 - 1.1e-12 47.0 52.8 2.9e-05 23.9 0.2 11.8 13 0 0 13 13 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMD00702.1 - 1.4e-10 41.1 34.6 0.0084 16.9 0.1 11.1 9 3 4 13 13 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 EMD00702.1 - 3.6e-09 36.2 1.6 2.1e-05 24.1 0.1 5.0 5 0 0 5 5 5 1 TPR repeat TPR_8 PF13181.6 EMD00702.1 - 4.6e-09 35.8 29.1 0.00071 19.6 0.0 8.5 10 0 0 10 10 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EMD00702.1 - 5.4e-09 36.2 15.6 0.0002 21.5 2.8 4.9 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EMD00702.1 - 2.8e-08 33.8 14.2 0.0008 19.5 1.3 6.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EMD00702.1 - 4.9e-06 26.8 15.6 0.12 13.0 0.1 7.6 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EMD00702.1 - 1.3e-05 25.2 8.8 0.43 11.1 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 EMD00702.1 - 0.0003 21.0 25.2 0.0043 17.3 1.6 8.1 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_15 PF13429.6 EMD00702.1 - 0.00059 19.1 1.2 0.00059 19.1 1.2 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EMD00702.1 - 0.0049 17.4 8.6 0.51 11.1 0.3 5.9 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 EMD00702.1 - 0.022 14.8 0.1 2.9 8.0 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Exo84_C PF16528.5 EMD00702.1 - 0.035 13.9 3.9 0.49 10.2 0.3 2.5 2 0 0 2 2 2 0 Exocyst component 84 C-terminal TPR_20 PF14561.6 EMD00702.1 - 0.049 14.0 12.1 3.3 8.1 0.3 5.6 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EMD00702.1 - 0.17 12.0 7.2 5.8 7.2 0.1 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_18 PF13512.6 EMD00702.1 - 1.9 8.6 9.4 9.8 6.3 1.2 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Fapy_DNA_glyco PF01149.24 EMD00703.1 - 4e-30 104.8 0.3 1.3e-29 103.1 0.1 2.0 2 1 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EMD00703.1 - 7.7e-22 77.1 0.0 1.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EMD00703.1 - 0.00058 18.7 0.0 0.0014 17.5 0.0 1.6 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) L_lac_phage_MSP PF06488.11 EMD00703.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein Arginase PF00491.21 EMD00708.1 - 1.3e-92 310.3 0.0 1.9e-92 309.7 0.0 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EMD00708.1 - 0.014 15.6 0.2 0.024 14.9 0.2 1.4 1 0 0 1 1 1 0 UPF0489 domain DAGK_cat PF00781.24 EMD00710.1 - 1.3e-27 95.9 0.0 2.1e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain zf-U1 PF06220.12 EMD00713.1 - 7e-08 32.1 0.1 1.4e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 U1 zinc finger SnAC PF14619.6 EMD00713.1 - 3.2 8.4 7.0 0.3 11.7 0.6 2.5 2 1 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex LssY_C PF14067.6 EMD00714.1 - 0.015 14.8 0.4 0.033 13.7 0.0 1.7 2 0 0 2 2 2 0 LssY C-terminus CK_II_beta PF01214.18 EMD00715.1 - 3.5e-78 261.6 0.9 4.4e-78 261.3 0.9 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 EMD00715.1 - 0.0057 16.7 0.3 0.0057 16.7 0.3 1.7 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases zf-Mss51 PF13824.6 EMD00715.1 - 0.024 14.7 1.1 0.75 9.9 0.4 2.4 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Uso1_p115_C PF04871.13 EMD00715.1 - 1.3 9.4 10.0 2.4 8.6 10.0 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region RIC1 PF07064.13 EMD00716.1 - 5.6e-86 288.0 0.1 8e-86 287.5 0.1 1.2 1 0 0 1 1 1 1 RIC1 Fungal_trans_2 PF11951.8 EMD00718.1 - 3.9e-05 22.6 0.3 0.00075 18.4 0.1 2.5 2 1 0 2 2 2 2 Fungal specific transcription factor domain La PF05383.17 EMD00720.1 - 1.7e-16 60.0 0.8 3.2e-16 59.1 0.8 1.4 1 0 0 1 1 1 1 La domain SOXp PF12336.8 EMD00720.1 - 0.0032 18.5 1.2 2.7 9.1 0.0 3.9 3 0 0 3 3 3 2 SOX transcription factor Mito_fiss_reg PF05308.11 EMD00721.1 - 8.4 6.4 10.3 4.1 7.4 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Pre-PUA PF17832.1 EMD00722.1 - 6.9e-25 87.6 0.4 9.2e-25 87.2 0.4 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EMD00722.1 - 2.6e-14 52.9 0.0 5.7e-14 51.8 0.0 1.6 1 1 0 1 1 1 1 PUA domain SET PF00856.28 EMD00724.1 - 1.1e-23 84.4 0.1 2.5e-23 83.3 0.1 1.6 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 EMD00724.1 - 5.2e-11 43.2 0.9 5.2e-11 43.2 0.9 2.5 2 1 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 EMD00724.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Nop52 PF05997.12 EMD00725.1 - 5.2e-69 232.3 0.1 6.3e-69 232.1 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Glyco_hydro_17 PF00332.18 EMD00726.1 - 5.1e-33 115.0 3.1 4e-32 112.1 3.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DapH_N PF08503.10 EMD00726.1 - 0.015 15.5 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal CPL PF08144.11 EMD00727.1 - 7.2e-21 75.0 0.0 7.5e-19 68.5 0.0 3.7 3 1 1 4 4 4 1 CPL (NUC119) domain Pox_A3L PF05288.11 EMD00727.1 - 0.34 10.9 1.2 33 4.6 0.3 2.6 2 0 0 2 2 2 0 Poxvirus A3L Protein Nnf1 PF03980.14 EMD00728.1 - 0.13 12.7 2.9 3.8 7.9 0.6 2.3 2 0 0 2 2 2 0 Nnf1 Ion_trans PF00520.31 EMD00729.1 - 3.4e-125 416.2 90.6 8.3e-45 152.9 9.4 5.0 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 EMD00729.1 - 0.00046 19.0 11.1 0.00046 19.0 11.1 6.1 7 0 0 7 7 7 3 Polycystin cation channel GPHH PF16905.5 EMD00729.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 EMD00729.1 - 0.0052 16.3 0.0 0.016 14.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EMD00729.1 - 0.075 13.0 0.0 0.3 11.1 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Asp_Glu_race PF01177.22 EMD00731.1 - 0.017 14.9 0.1 0.17 11.7 0.1 2.0 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase FPN1 PF06963.12 EMD00732.1 - 6.1e-113 377.7 15.1 7.9e-113 377.3 15.1 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) PHD PF00628.29 EMD00733.1 - 2.9e-09 36.7 7.7 5.3e-09 35.8 7.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EMD00733.1 - 0.0016 17.9 5.1 0.0035 16.9 5.1 1.6 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 EMD00733.1 - 0.034 14.5 2.2 0.034 14.5 2.2 2.1 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 EMD00733.1 - 4.9 7.1 9.0 0.95 9.4 4.7 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_pol_Rpb4 PF03874.16 EMD00735.1 - 9.9e-09 35.6 4.3 2.7e-08 34.2 4.3 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 ABC_membrane PF00664.23 EMD00736.1 - 1.3e-40 139.8 12.2 1.7e-40 139.4 12.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EMD00736.1 - 1.5e-30 106.5 0.0 2.7e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EMD00736.1 - 2.1e-05 24.0 0.0 5.7e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EMD00736.1 - 0.0074 16.5 1.1 0.12 12.6 0.4 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Syntaxin-5_N PF11416.8 EMD00736.1 - 0.094 12.0 0.1 0.24 10.7 0.1 1.7 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain Nop PF01798.18 EMD00738.1 - 3.2e-81 272.2 0.0 4.5e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EMD00738.1 - 1.3e-22 79.9 2.3 3.1e-22 78.7 2.3 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF4607 PF15380.6 EMD00738.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) Actin PF00022.19 EMD00739.1 - 7.7e-18 64.3 0.0 1.3e-15 56.9 0.0 3.1 2 1 0 2 2 2 1 Actin COG5 PF10392.9 EMD00740.1 - 0.0039 17.4 0.2 0.011 15.9 0.2 1.8 1 0 0 1 1 1 1 Golgi transport complex subunit 5 COG7 PF10191.9 EMD00740.1 - 0.0055 15.0 0.0 0.013 13.7 0.0 1.6 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) Baculo_PEP_C PF04513.12 EMD00740.1 - 0.047 13.7 2.1 0.11 12.6 1.4 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4736 PF15883.5 EMD00740.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) WXG100 PF06013.12 EMD00740.1 - 0.2 11.9 2.6 6.9 7.0 0.2 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG PARP PF00644.20 EMD00741.1 - 3.9e-10 39.6 0.1 8.2e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 EMD00741.1 - 6e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GEN1_C PF18380.1 EMD00744.1 - 4.2e-33 114.4 0.0 1.3e-32 112.8 0.0 1.9 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 EMD00744.1 - 3.8e-24 84.9 0.0 8.7e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EMD00744.1 - 7.9e-08 32.7 0.0 1.9e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EMD00744.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing STAC2_u1 PF16664.5 EMD00744.1 - 0.13 12.7 2.8 0.18 12.3 0.0 2.5 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 TPT PF03151.16 EMD00745.1 - 6.1e-34 117.7 16.5 7.4e-34 117.4 16.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EMD00745.1 - 6.1e-12 45.3 18.3 1.3e-11 44.3 18.3 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EMD00745.1 - 1.5 9.0 31.3 0.48 10.6 4.1 2.4 3 0 0 3 3 3 0 EamA-like transporter family Glyco_hydro_3_C PF01915.22 EMD00746.1 - 2.1e-59 200.9 0.0 4.1e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMD00746.1 - 4.1e-45 154.5 0.0 7.3e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMD00746.1 - 6.4e-22 77.4 0.1 1.6e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EMD00746.1 - 5.4e-11 42.5 0.0 9.5e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.6 EMD00746.1 - 0.018 15.4 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family GFO_IDH_MocA PF01408.22 EMD00747.1 - 6.6e-18 65.7 0.0 1.3e-17 64.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 EMD00748.1 - 3.1e-31 108.6 14.6 3.1e-31 108.6 14.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EMD00748.1 - 3.7e-11 42.6 2.6 3.7e-11 42.6 2.6 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EMD00748.1 - 2.3e-08 33.0 1.1 2.3e-08 33.0 1.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-BED PF02892.15 EMD00753.1 - 0.02 14.9 1.9 0.041 13.9 1.9 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.6 EMD00753.1 - 0.4 11.6 4.7 1.3 10.0 4.7 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMD00753.1 - 8.3 7.1 9.0 0.84 10.2 3.9 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type TPR_1 PF00515.28 EMD00754.1 - 7e-41 136.4 23.0 1.7e-09 37.0 0.0 8.4 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EMD00754.1 - 1.2e-38 128.1 26.3 3.2e-07 30.0 0.1 8.3 8 1 1 9 9 8 7 Tetratricopeptide repeat DnaJ PF00226.31 EMD00754.1 - 2.2e-28 98.2 2.4 7.5e-28 96.4 2.4 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 EMD00754.1 - 2.1e-26 92.3 14.7 5.1e-08 33.4 0.0 5.8 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EMD00754.1 - 2.9e-21 75.7 22.8 0.00054 20.4 0.1 5.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 EMD00754.1 - 1e-20 72.6 13.4 6.9e-05 23.3 0.1 7.3 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EMD00754.1 - 2.4e-20 71.9 28.9 2.2e-06 27.3 0.2 7.5 7 1 1 8 8 8 3 TPR repeat TPR_8 PF13181.6 EMD00754.1 - 9.4e-19 66.0 12.4 0.0033 17.5 0.1 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EMD00754.1 - 2e-18 66.4 21.8 6.8e-05 23.1 1.9 6.3 3 3 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EMD00754.1 - 1.6e-17 62.1 14.7 0.0035 17.3 0.0 7.3 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 EMD00754.1 - 9.5e-17 60.1 22.6 0.0015 18.7 0.1 8.3 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 EMD00754.1 - 6.6e-14 51.5 22.5 0.0082 16.7 0.2 7.8 8 1 0 8 8 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EMD00754.1 - 3.3e-11 43.3 13.6 0.0032 17.7 2.4 4.9 2 2 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EMD00754.1 - 1.3e-08 34.4 25.4 0.05 13.5 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EMD00754.1 - 2.2e-08 34.1 14.1 0.00037 20.6 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 EMD00754.1 - 1.6e-06 28.2 13.0 0.076 13.7 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EMD00754.1 - 3.7e-06 26.4 12.5 0.15 11.2 0.0 4.5 2 2 0 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMD00754.1 - 5.1e-06 26.5 5.7 0.17 11.9 0.0 4.5 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 EMD00754.1 - 6.4e-06 26.7 12.4 0.41 11.1 0.0 5.1 2 2 2 5 5 5 3 Bacterial transcriptional activator domain PPR PF01535.20 EMD00754.1 - 0.00049 20.2 1.5 10 6.6 0.0 5.5 7 0 0 7 7 5 0 PPR repeat TPR_MalT PF17874.1 EMD00754.1 - 0.001 18.5 8.1 0.37 10.1 0.1 3.5 3 1 1 4 4 4 2 MalT-like TPR region TPR_20 PF14561.6 EMD00754.1 - 0.0016 18.7 15.6 0.11 12.8 0.7 5.1 3 3 1 4 4 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EMD00754.1 - 0.0044 17.5 7.2 3.9 7.9 0.1 4.0 2 2 2 4 4 4 1 Alkyl sulfatase dimerisation NARP1 PF12569.8 EMD00754.1 - 0.007 15.3 6.7 0.019 13.9 0.0 3.4 2 2 1 3 3 3 1 NMDA receptor-regulated protein 1 DUF3597 PF12200.8 EMD00754.1 - 0.045 14.3 2.4 0.18 12.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) MAS20 PF02064.15 EMD00754.1 - 0.068 13.3 0.6 11 6.1 0.0 3.8 2 2 1 3 3 3 0 MAS20 protein import receptor TOM20_plant PF06552.12 EMD00754.1 - 0.077 12.7 2.3 1.2 8.9 0.1 2.9 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Rapsyn_N PF10579.9 EMD00754.1 - 0.12 12.5 0.9 3.1 8.0 0.0 3.5 3 2 1 4 4 3 0 Rapsyn N-terminal myristoylation and linker region TPM_phosphatase PF04536.14 EMD00754.1 - 0.13 12.4 0.6 19 5.4 0.0 3.1 3 0 0 3 3 3 0 TPM domain MIT PF04212.18 EMD00754.1 - 0.18 11.9 16.0 4.9 7.3 0.3 5.4 4 1 2 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 EMD00754.1 - 2 8.5 8.0 37 4.4 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 EMD00754.1 - 2.7 7.4 5.8 10 5.5 0.0 3.7 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like KH_1 PF00013.29 EMD00755.1 - 3.3e-42 142.2 8.6 6.9e-17 61.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EMD00755.1 - 1e-10 41.3 13.5 0.0012 18.6 1.1 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 EMD00755.1 - 1.8e-08 34.1 5.7 0.022 14.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EMD00755.1 - 4.4e-05 23.5 5.8 0.11 12.5 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain NmrA PF05368.13 EMD00756.1 - 7.3e-44 150.1 0.0 5.7e-42 143.9 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMD00756.1 - 3.3e-12 46.7 0.0 6.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EMD00756.1 - 0.004 16.2 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fringe PF02434.16 EMD00757.1 - 4.1e-08 33.0 0.1 8.2e-08 32.0 0.1 1.5 1 1 0 1 1 1 1 Fringe-like 2OG-FeII_Oxy_3 PF13640.6 EMD00758.1 - 2.8e-14 53.8 0.1 4.3e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EMD00758.1 - 0.092 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily EBP PF05241.12 EMD00760.1 - 0.53 9.7 11.0 1.5 8.3 11.0 1.9 1 1 0 1 1 1 0 Emopamil binding protein MIP PF00230.20 EMD00761.1 - 4.5e-51 173.7 2.7 5.4e-51 173.5 2.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_S7e PF01251.18 EMD00762.1 - 4.4e-80 267.8 0.0 5.1e-80 267.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Zn_clus PF00172.18 EMD00763.1 - 1.2e-08 34.9 11.9 2.7e-08 33.8 11.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EMD00764.1 - 6.9e-33 114.0 77.1 2.8e-31 108.7 47.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SF3b10 PF07189.11 EMD00766.1 - 7.7e-35 118.9 0.0 8.5e-35 118.7 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 EMD00767.1 - 5.6e-62 209.2 0.0 8.1e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 MAGE family Ras PF00071.22 EMD00768.1 - 1.5e-57 193.8 0.0 1.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EMD00768.1 - 6.4e-35 120.0 0.0 1e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EMD00768.1 - 2.2e-14 53.3 0.0 3.5e-14 52.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EMD00768.1 - 1.8e-07 30.7 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EMD00768.1 - 2.6e-07 30.4 0.0 4.7e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMD00768.1 - 2.4e-05 24.4 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EMD00768.1 - 0.00041 20.8 0.1 0.00063 20.2 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EMD00768.1 - 0.025 14.5 0.1 2.6 7.9 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase Rad51 PF08423.11 EMD00769.1 - 2.8e-06 26.8 0.1 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 Rad51 DUF3318 PF11780.8 EMD00769.1 - 0.0016 18.4 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3318) ATPase PF06745.13 EMD00769.1 - 0.047 13.0 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 KaiC DIOX_N PF14226.6 EMD00770.1 - 3.6e-30 105.1 0.0 5e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EMD00770.1 - 2.1e-20 73.1 0.0 3.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UDPGT PF00201.18 EMD00771.1 - 6.9e-06 25.1 0.0 0.059 12.2 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase DUF1687 PF07955.11 EMD00771.1 - 0.033 14.7 0.0 0.048 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Lac_bphage_repr PF06543.12 EMD00771.1 - 0.042 13.8 0.4 1.7 8.7 0.3 2.4 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor Glutaredoxin PF00462.24 EMD00772.1 - 3.2e-19 68.9 0.0 4.3e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EMD00772.1 - 0.00055 20.3 0.0 0.00066 20.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 EMD00772.1 - 0.0014 18.6 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 EMD00772.1 - 0.0024 18.3 0.1 0.0044 17.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 EMD00772.1 - 0.035 14.1 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.20 EMD00772.1 - 0.041 13.7 0.2 0.46 10.2 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF1857 PF08982.11 EMD00773.1 - 7.2e-50 168.7 0.0 8e-50 168.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Glyco_transf_90 PF05686.12 EMD00774.1 - 4.6e-17 62.0 7.8 1.3e-13 50.6 7.3 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 KIX_2 PF16987.5 EMD00776.1 - 1.1e-09 38.2 0.6 1.1e-09 38.2 0.6 3.4 3 0 0 3 3 3 1 KIX domain PIN_9 PF18477.1 EMD00776.1 - 0.18 12.2 0.7 2.7 8.4 0.1 2.7 2 0 0 2 2 2 0 PIN like domain zf-C2H2 PF00096.26 EMD00777.1 - 2.8e-06 27.4 18.2 2.1e-05 24.7 3.8 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMD00777.1 - 4.6e-05 23.7 3.8 4.6e-05 23.7 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EMD00777.1 - 4.8e-05 23.9 2.3 4.8e-05 23.9 2.3 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMD00777.1 - 0.00065 19.9 1.0 0.0017 18.6 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EMD00777.1 - 0.00098 19.1 1.8 0.002 18.1 1.8 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 EMD00777.1 - 0.16 12.4 0.7 0.39 11.2 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 EMD00777.1 - 0.3 11.8 7.0 0.28 11.9 2.4 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_8 PF15909.5 EMD00777.1 - 0.32 11.3 2.9 0.66 10.3 2.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 EMD00777.1 - 0.34 11.4 1.6 0.79 10.2 1.6 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 EMD00777.1 - 0.54 10.9 12.2 0.13 12.9 1.4 3.4 2 1 2 4 4 4 0 FOXP coiled-coil domain DUF4097 PF13349.6 EMD00779.1 - 0.00034 20.0 2.1 0.61 9.4 0.1 3.1 2 1 1 3 3 3 3 Putative adhesin Pkinase PF00069.25 EMD00780.1 - 9.6e-42 143.2 0.0 1.4e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD00780.1 - 1.1e-31 110.1 0.0 1.5e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EMD00780.1 - 0.044 12.6 0.2 0.12 11.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Spindle_Spc25 PF08234.12 EMD00781.1 - 2e-20 72.8 0.0 4.1e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 HMMR_N PF15905.5 EMD00781.1 - 0.023 14.2 7.1 0.038 13.5 7.1 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FAM76 PF16046.5 EMD00781.1 - 0.21 10.9 2.6 0.34 10.2 2.6 1.4 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 EMD00781.1 - 1 8.4 6.3 1.6 7.8 6.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 E1-E2_ATPase PF00122.20 EMD00784.1 - 2e-36 125.2 2.9 2e-36 125.2 2.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EMD00784.1 - 1e-34 119.8 18.4 7.6e-29 100.7 1.6 3.6 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EMD00784.1 - 3.9e-21 76.3 0.0 2e-09 38.1 0.0 3.8 3 2 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMD00784.1 - 2.5e-18 65.9 0.0 1.1e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EMD00784.1 - 3.2e-10 39.5 0.0 7.1e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMD00784.1 - 7.4e-06 25.9 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMD00784.1 - 0.17 12.2 0.0 13 6.1 0.0 2.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF443 PF04276.12 EMD00784.1 - 0.96 9.2 8.0 1.7 8.4 0.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF443) Reticulon PF02453.17 EMD00785.1 - 4.3e-27 95.0 6.4 7.2e-27 94.3 6.4 1.4 1 0 0 1 1 1 1 Reticulon DUF4758 PF15950.5 EMD00785.1 - 8.8e-06 26.1 0.4 8.8e-06 26.1 0.4 2.0 2 0 0 2 2 2 1 Putative sperm flagellar membrane protein Phage_holin_3_6 PF07332.11 EMD00785.1 - 0.17 12.0 0.2 0.17 12.0 0.2 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FUSC_2 PF13515.6 EMD00785.1 - 1.8 8.7 11.3 5.1 7.2 1.2 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like ATP-synt_B PF00430.18 EMD00785.1 - 3.4 7.8 9.0 0.056 13.5 0.7 2.2 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) 5_nucleotid_C PF02872.18 EMD00786.1 - 1.5e-36 126.0 0.0 2.5e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EMD00786.1 - 3.1e-05 24.6 0.0 5.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homeobox_KN PF05920.11 EMD00787.1 - 3e-14 52.6 0.6 7.9e-14 51.3 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 EMD00787.1 - 2.3e-05 24.3 0.0 2.3e-05 24.3 0.0 2.9 4 0 0 4 4 4 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 EMD00787.1 - 0.0018 18.1 0.2 0.0059 16.4 0.2 1.9 1 0 0 1 1 1 1 Homeodomain Zn_clus PF00172.18 EMD00787.1 - 0.0077 16.3 7.2 0.03 14.5 7.2 2.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EMD00787.1 - 0.022 15.6 1.6 0.022 15.6 1.6 6.0 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EMD00787.1 - 0.088 13.3 21.0 0.36 11.4 1.8 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EMD00787.1 - 3.7 7.9 9.7 79 3.7 0.3 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Aldolase_II PF00596.21 EMD00788.1 - 5.7e-49 166.6 0.1 7.1e-49 166.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AAA PF00004.29 EMD00789.1 - 8.9e-16 58.5 0.0 1.9e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EMD00789.1 - 1.6e-12 47.4 0.2 3.8e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 EMD00789.1 - 1.5e-09 38.5 0.0 1.9e-08 34.9 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMD00789.1 - 3.3e-08 33.9 0.0 3.1e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain BAH PF01426.18 EMD00789.1 - 4.8e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 EMD00789.1 - 0.0013 19.1 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EMD00789.1 - 0.035 14.3 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EMD00789.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EMD00789.1 - 0.07 13.5 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EMD00789.1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EMD00789.1 - 0.078 12.7 0.9 0.19 11.5 0.4 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EMD00789.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ssDBP PF17878.1 EMD00789.1 - 0.16 12.2 0.1 0.51 10.6 0.1 1.8 1 0 0 1 1 1 0 Single-stranded DNA-binding protein TsaE PF02367.17 EMD00789.1 - 0.18 11.8 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-C2H2_2 PF12756.7 EMD00791.1 - 2.1e-05 24.8 0.2 3.5e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) LEA_6 PF10714.9 EMD00794.1 - 0.029 14.4 0.1 0.087 12.9 0.1 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 BDV_P40 PF06407.11 EMD00795.1 - 0.24 10.5 0.2 0.31 10.1 0.2 1.1 1 0 0 1 1 1 0 Borna disease virus P40 protein CDC45 PF02724.14 EMD00796.1 - 2.2e-226 753.1 16.9 3.4e-225 749.2 16.9 3.2 1 1 0 1 1 1 1 CDC45-like protein Peptidase_M17_N PF02789.17 EMD00796.1 - 0.039 13.8 0.4 0.18 11.7 0.4 2.1 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Trypan_PARP PF05887.11 EMD00796.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.5 2 2 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SR-25 PF10500.9 EMD00796.1 - 0.99 9.0 29.7 0.8 9.3 1.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EMD00796.1 - 1.7 7.9 29.9 0.066 12.5 14.3 2.2 2 0 0 2 2 2 0 BUD22 NUDIX PF00293.28 EMD00799.1 - 2.5e-19 69.6 0.0 3.1e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Helicase_C PF00271.31 EMD00800.1 - 8.4e-21 74.4 0.0 6.3e-16 58.7 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EMD00800.1 - 4e-20 72.3 0.0 8.8e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EMD00800.1 - 9.4e-05 23.1 0.1 0.00022 21.9 0.1 1.6 1 0 0 1 1 1 1 RecQ zinc-binding UBA2_C PF16195.5 EMD00800.1 - 0.17 12.6 0.3 0.43 11.3 0.3 1.7 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus tRNA-synt_1 PF00133.22 EMD00801.1 - 1.5e-198 660.9 0.0 1.3e-196 654.5 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EMD00801.1 - 2.5e-22 79.5 0.0 1.4e-20 73.8 0.0 2.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EMD00801.1 - 2.2e-15 56.3 0.0 3.7e-05 22.7 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EMD00801.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain PAS_9 PF13426.7 EMD00802.1 - 6e-17 61.8 0.0 4.9e-16 58.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EMD00802.1 - 5.4e-06 26.4 0.0 1.7e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMD00802.1 - 0.0047 17.2 0.1 0.13 12.5 0.0 3.1 4 0 0 4 4 4 1 PAS fold Catalase PF00199.19 EMD00803.1 - 6.9e-24 84.7 0.0 2.8e-23 82.6 0.0 1.8 1 1 0 1 1 1 1 Catalase DUF2846 PF11008.8 EMD00803.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) zf-C2H2 PF00096.26 EMD00804.1 - 6.7e-08 32.6 23.3 0.00034 20.9 1.1 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMD00804.1 - 2.5e-05 24.7 18.1 0.024 15.5 0.1 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMD00804.1 - 0.00038 20.8 13.9 0.0044 17.4 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 EMD00804.1 - 0.00056 20.6 1.7 1.1 10.0 0.2 2.4 2 1 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 EMD00804.1 - 0.034 14.2 1.4 0.034 14.2 1.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EMD00804.1 - 0.045 14.1 0.4 0.045 14.1 0.4 2.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EMD00804.1 - 0.053 13.9 10.1 0.15 12.4 1.4 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 EMD00804.1 - 0.81 10.0 8.3 0.65 10.3 5.6 2.3 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 EMD00807.1 - 3.2e-08 33.6 13.8 0.0065 16.9 0.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMD00807.1 - 3.4e-05 24.3 18.1 0.0031 18.2 0.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EMD00807.1 - 0.002 18.8 2.2 1.7 9.3 0.8 2.4 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats CGGC PF08821.11 EMD00807.1 - 0.38 11.0 2.7 0.42 10.8 0.5 2.1 2 1 0 2 2 2 0 CGGC domain zf-C2H2_6 PF13912.6 EMD00807.1 - 0.97 9.5 10.7 0.23 11.5 0.9 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Band_7 PF01145.25 EMD00809.1 - 1.6e-30 106.4 0.4 3e-30 105.5 0.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EMD00809.1 - 7e-25 86.9 1.3 2e-24 85.4 1.3 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 EMD00809.1 - 0.035 13.4 1.1 0.047 13.0 0.5 1.5 2 0 0 2 2 2 0 Poxvirus A11 Protein Band_7_1 PF13421.6 EMD00809.1 - 0.036 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF2975 PF11188.8 EMD00811.1 - 0.13 12.2 1.5 0.2 11.5 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) UPF0060 PF02694.15 EMD00811.1 - 0.32 11.2 2.0 0.51 10.6 2.0 1.3 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family Peptidase_C14 PF00656.22 EMD00812.1 - 3.6e-05 23.8 0.0 5.7e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EMD00812.1 - 0.023 14.7 1.9 0.37 10.8 1.1 2.6 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain Abhydrolase_3 PF07859.13 EMD00813.1 - 1e-08 35.3 0.0 0.00024 21.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMD00813.1 - 1.9e-05 25.3 6.8 3.1e-05 24.7 6.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EMD00813.1 - 0.002 17.8 0.1 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EMD00813.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 EMD00813.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 EMD00813.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 EMD00813.1 - 0.1 11.8 0.0 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EMD00813.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) EMC3_TMCO1 PF01956.16 EMD00814.1 - 0.72 9.6 3.9 1.4 8.6 3.9 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Inhibitor_I78 PF11720.8 EMD00815.1 - 4.7e-09 36.2 0.0 6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EMD00815.1 - 0.013 16.1 0.0 0.017 15.8 0.0 1.2 1 0 0 1 1 1 0 Potato inhibitor I family SURF4 PF02077.15 EMD00817.1 - 5.7e-92 308.1 7.1 6.4e-92 307.9 7.1 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.11 EMD00817.1 - 0.3 11.3 7.7 0.22 11.7 1.4 2.9 3 1 0 3 3 3 0 HR-like lesion-inducing DUF3325 PF11804.8 EMD00817.1 - 0.96 9.6 16.2 0.067 13.4 6.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3325) Nup84_Nup100 PF04121.13 EMD00818.1 - 6.3e-159 530.4 12.3 6.3e-159 530.4 12.3 1.6 2 0 0 2 2 2 1 Nuclear pore protein 84 / 107 Peptidase_S11 PF00768.20 EMD00818.1 - 0.016 14.7 0.2 0.045 13.2 0.2 1.7 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase YqzH PF14164.6 EMD00818.1 - 0.058 13.5 2.1 1.4 9.0 0.2 3.5 3 0 0 3 3 3 0 YqzH-like protein MLTR_LBD PF17765.1 EMD00818.1 - 0.15 12.2 3.9 0.12 12.5 0.6 2.6 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain DUF3336 PF11815.8 EMD00819.1 - 3.1e-32 111.1 0.0 7.7e-31 106.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EMD00819.1 - 1.4e-09 38.5 0.2 1.3e-08 35.3 0.1 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase V-SNARE_C PF12352.8 EMD00820.1 - 4.1e-14 52.6 0.4 4.1e-14 52.6 0.4 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.11 EMD00820.1 - 0.0027 18.2 5.2 0.0027 18.2 5.2 1.8 2 1 0 2 2 2 1 Syntaxin 6, N-terminal MtrG PF04210.13 EMD00820.1 - 0.077 12.9 0.2 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Muted PF14942.6 EMD00820.1 - 0.46 10.8 5.8 3.7 7.9 3.2 2.4 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Sec34 PF04136.15 EMD00820.1 - 2.6 7.9 10.5 0.36 10.7 2.5 2.7 2 1 0 3 3 3 0 Sec34-like family RWD PF05773.22 EMD00821.1 - 2e-24 86.1 2.2 3.3e-24 85.4 2.2 1.4 1 0 0 1 1 1 1 RWD domain ketoacyl-synt PF00109.26 EMD00821.1 - 0.04 13.5 0.2 0.057 13.0 0.2 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DFRP_C PF16543.5 EMD00821.1 - 0.041 14.4 12.2 0.11 13.1 12.0 1.8 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 TPR_8 PF13181.6 EMD00822.1 - 1.3e-10 40.6 0.0 4.4e-06 26.5 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMD00822.1 - 3.3e-09 36.2 0.0 0.00011 22.1 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMD00822.1 - 3.7e-09 37.1 3.1 0.0074 16.9 0.7 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EMD00822.1 - 3.5e-08 33.8 5.0 0.059 13.9 0.2 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EMD00822.1 - 2.8e-07 30.8 11.9 0.072 13.9 0.1 5.6 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EMD00822.1 - 1.8e-06 27.6 2.9 0.016 14.6 0.0 3.2 2 1 1 3 3 3 2 MalT-like TPR region TPR_12 PF13424.6 EMD00822.1 - 2.1e-06 27.9 3.2 0.0051 17.1 0.1 3.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EMD00822.1 - 5.1e-06 26.1 4.1 0.00024 20.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EMD00822.1 - 4.1e-05 23.2 0.0 0.0019 17.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EMD00822.1 - 0.0006 20.0 0.3 4.4 7.6 0.0 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EMD00822.1 - 0.00085 19.0 0.0 0.13 11.9 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 EMD00822.1 - 0.001 19.6 10.6 1 10.1 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 EMD00822.1 - 0.0045 17.3 3.9 1 9.7 0.1 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 EMD00822.1 - 0.012 15.3 2.4 0.83 9.3 0.0 2.9 2 2 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 EMD00822.1 - 0.031 14.7 0.1 57 4.4 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EMD00822.1 - 0.065 13.1 3.4 1.8 8.5 0.0 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF2207 PF09972.9 EMD00824.1 - 0.24 10.1 0.0 0.27 10.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HMG_box PF00505.19 EMD00825.1 - 8.2e-07 29.3 0.7 8.8e-07 29.3 0.7 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box ATP-synt_10 PF05176.14 EMD00827.1 - 1.1e-66 224.7 0.0 1.5e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein PTCB-BRCT PF12738.7 EMD00828.1 - 2.3e-35 120.4 1.2 2.2e-21 75.6 0.4 4.7 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 EMD00828.1 - 9.3e-33 112.5 0.3 3.3e-12 46.6 0.1 6.7 7 0 0 7 7 7 4 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EMD00828.1 - 1.7e-24 85.6 0.2 1.9e-22 79.0 0.0 3.5 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EMD00828.1 - 5.2e-22 78.1 0.7 5.6e-06 26.7 0.1 6.0 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EMD00828.1 - 2.6e-09 37.2 1.0 0.018 15.4 0.0 3.8 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EMD00828.1 - 2.8e-05 24.1 0.2 0.69 10.0 0.0 3.9 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain GIY-YIG PF01541.24 EMD00828.1 - 0.015 15.5 0.6 0.12 12.7 0.0 2.4 2 0 0 2 2 2 0 GIY-YIG catalytic domain AT_hook PF02178.19 EMD00828.1 - 2.1 8.5 7.9 11 6.3 7.9 2.3 1 0 0 1 1 1 0 AT hook motif CN_hydrolase PF00795.22 EMD00829.1 - 1.8e-55 188.1 0.0 2e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DHO_dh PF01180.21 EMD00830.1 - 1.5e-19 70.3 0.0 1.9e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 EMD00830.1 - 0.081 12.3 5.6 0.15 11.4 5.6 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase SF3A2 PF16835.5 EMD00832.1 - 3.9e-36 123.3 0.1 5.7e-36 122.8 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EMD00832.1 - 1e-05 25.7 0.5 2.1e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EMD00832.1 - 0.00087 19.2 0.2 0.0013 18.7 0.2 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 EMD00832.1 - 0.06 12.9 1.5 0.11 12.1 1.5 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF1168 PF06658.12 EMD00833.1 - 1.7e-37 128.3 8.9 2.2e-37 127.9 8.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 EMD00833.1 - 0.014 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic SUR7 PF06687.12 EMD00834.1 - 2.8e-12 46.7 14.2 1.6e-11 44.2 13.7 1.9 1 1 1 2 2 2 1 SUR7/PalI family DUF962 PF06127.11 EMD00834.1 - 0.046 13.8 0.7 0.43 10.7 0.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Hum_adeno_E3A PF05393.11 EMD00834.1 - 0.74 9.8 4.4 11 6.0 0.1 2.8 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein Arginase PF00491.21 EMD00836.1 - 8.2e-82 274.9 0.9 1e-81 274.5 0.9 1.0 1 0 0 1 1 1 1 Arginase family Peptidase_M49 PF03571.15 EMD00837.1 - 9.3e-244 809.9 0.0 1.1e-243 809.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Death PF00531.22 EMD00837.1 - 0.0099 16.0 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 1 Death domain CNP_C_terminal PF17839.1 EMD00837.1 - 0.093 13.5 1.6 0.12 13.2 0.1 2.0 2 0 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase Shisa PF13908.6 EMD00838.1 - 8.3 6.6 8.2 0.64 10.2 0.3 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator NAD_binding_5 PF07994.12 EMD00839.1 - 3.4e-143 476.9 0.0 4.1e-143 476.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EMD00839.1 - 1.4e-46 157.2 0.3 2.4e-46 156.5 0.3 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase His_Phos_1 PF00300.22 EMD00840.1 - 6.7e-28 97.7 0.1 2.7e-13 50.0 0.2 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EMD00840.1 - 3.6e-05 23.3 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) P5-ATPase PF12409.8 EMD00840.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 P5-type ATPase cation transporter EAF PF09816.9 EMD00841.1 - 7.2e-13 48.8 0.1 1.8e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Ank_2 PF12796.7 EMD00842.1 - 2.3e-45 153.1 6.0 1.1e-10 41.9 0.8 5.5 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMD00842.1 - 1.8e-37 126.9 9.4 4.8e-09 36.3 0.3 8.1 4 4 4 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMD00842.1 - 3.5e-35 119.9 8.4 7e-07 29.7 0.0 7.1 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMD00842.1 - 4.4e-31 103.4 5.6 0.00046 20.4 0.0 9.8 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 EMD00842.1 - 1.9e-19 69.1 17.0 8.9e-05 22.8 0.1 9.4 10 0 0 10 10 10 5 Ankyrin repeat HTH_20 PF12840.7 EMD00842.1 - 0.041 14.0 0.0 0.17 11.9 0.0 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain VWA_3_C PF18571.1 EMD00842.1 - 2.8 7.9 4.8 23 4.9 0.0 3.7 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Peptidase_C97 PF05903.14 EMD00843.1 - 1.2e-34 119.4 0.0 1.5e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EMD00843.1 - 0.002 18.4 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.12 EMD00843.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Iso_dh PF00180.20 EMD00844.1 - 4.4e-86 289.2 0.0 5.1e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HATPase_c PF02518.26 EMD00847.1 - 1.5e-22 80.3 0.0 3.6e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EMD00847.1 - 1e-19 70.7 0.6 1e-19 70.7 0.6 2.0 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 EMD00847.1 - 6e-10 39.0 0.2 1.3e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EMD00847.1 - 2.9e-06 27.5 0.1 6.7e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EMD00847.1 - 0.0052 17.0 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EMD00847.1 - 0.082 13.2 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 EMD00847.1 - 0.098 12.7 0.0 0.81 9.7 0.0 2.5 2 1 1 3 3 3 0 PAS fold Mago_nashi PF02792.14 EMD00848.1 - 2.4e-72 241.7 0.4 2.7e-72 241.5 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 EMD00849.1 - 6.5e-96 322.0 8.2 1e-95 321.3 8.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EMD00849.1 - 8.1e-57 191.1 1.2 2.3e-56 189.6 1.2 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EMD00849.1 - 2.6e-55 185.8 0.0 7.5e-55 184.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EMD00849.1 - 3e-13 50.1 2.3 4.8e-10 39.7 0.0 3.3 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EMD00849.1 - 2.3e-09 37.5 2.1 0.016 15.6 0.0 4.8 2 2 2 4 4 4 4 HEAT repeats Coatomer_g_Cpla PF16381.5 EMD00849.1 - 8.4e-05 22.7 0.1 0.0054 16.9 0.0 3.1 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EMD00849.1 - 0.0025 17.9 2.4 2.3 8.7 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EMD00849.1 - 0.13 12.8 0.5 6.2 7.4 0.1 3.6 3 0 0 3 3 3 0 HEAT-like repeat Ribosomal_L13 PF00572.18 EMD00850.1 - 8.9e-11 42.1 0.0 2.5e-07 31.0 0.0 2.4 1 1 1 2 2 2 2 Ribosomal protein L13 DUF1604 PF07713.13 EMD00851.1 - 4.3e-38 129.0 1.0 4.3e-38 129.0 1.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EMD00851.1 - 1.1e-07 31.6 2.6 1.4e-06 28.0 1.4 2.8 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EMD00851.1 - 0.32 11.1 4.1 0.15 12.1 0.6 2.4 2 0 0 2 2 2 0 G-patch domain Pkinase PF00069.25 EMD00852.1 - 3.2e-70 236.5 0.0 5.2e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD00852.1 - 3.6e-39 134.6 0.0 1.2e-38 132.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EMD00852.1 - 4e-18 64.9 0.2 6.5e-18 64.3 0.2 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 EMD00852.1 - 1.8e-05 24.2 0.0 0.00018 21.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EMD00852.1 - 0.00013 21.4 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EMD00852.1 - 0.00068 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EMD00852.1 - 0.0028 17.6 0.1 0.026 14.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 EMD00852.1 - 0.078 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Ribosomal_L29 PF00831.23 EMD00853.1 - 1.5e-17 63.3 2.0 1.5e-17 63.3 2.0 1.7 2 0 0 2 2 2 1 Ribosomal L29 protein MPS2 PF17060.5 EMD00853.1 - 0.0007 19.0 1.9 0.00091 18.6 1.9 1.0 1 0 0 1 1 1 1 Monopolar spindle protein 2 Snapin_Pallidin PF14712.6 EMD00853.1 - 0.047 14.1 4.6 0.081 13.4 4.6 1.4 1 0 0 1 1 1 0 Snapin/Pallidin NPV_P10 PF05531.12 EMD00853.1 - 0.16 12.5 1.5 0.29 11.6 1.5 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Homeodomain PF00046.29 EMD00854.1 - 1.3e-13 50.5 2.0 4.1e-13 48.9 2.0 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EMD00854.1 - 0.012 15.5 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain FRB_dom PF08771.11 EMD00854.1 - 0.18 12.2 0.3 0.53 10.7 0.3 1.7 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain PLA2_B PF01735.18 EMD00856.1 - 1.2e-17 63.5 0.1 2.5e-08 32.8 0.0 2.4 2 1 0 2 2 2 2 Lysophospholipase catalytic domain HAD_2 PF13419.6 EMD00857.1 - 1.2e-16 61.3 0.0 1.7e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMD00857.1 - 5.4e-07 30.1 0.0 3e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EMD00857.1 - 0.00021 21.7 0.0 0.0003 21.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EMD00857.1 - 0.0038 17.2 0.2 0.0079 16.2 0.2 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like AAA_16 PF13191.6 EMD00858.1 - 1.8e-07 31.7 0.1 4.1e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EMD00858.1 - 0.0013 18.4 0.0 0.015 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EMD00858.1 - 0.005 16.5 0.0 0.015 15.0 0.0 1.8 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 EMD00858.1 - 0.0058 16.3 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EMD00858.1 - 0.012 15.1 0.0 0.079 12.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EMD00858.1 - 0.039 13.1 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EMD00858.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EMD00858.1 - 0.11 12.8 0.2 6.7 7.0 0.3 2.9 2 1 0 2 2 2 0 AAA domain CLU PF13236.6 EMD00859.1 - 1.1e-73 247.7 0.0 2.1e-73 246.8 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EMD00859.1 - 8e-51 172.5 0.0 2.1e-50 171.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 EMD00859.1 - 2.5e-23 82.2 0.1 5.6e-23 81.1 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 EMD00859.1 - 5.3e-19 68.3 12.4 1.5e-08 34.8 0.1 4.2 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EMD00859.1 - 1.1e-17 63.3 3.6 0.00012 21.9 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat DUF727 PF05303.12 EMD00859.1 - 4e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 EMD00859.1 - 0.00064 19.7 0.5 0.35 11.2 0.6 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EMD00859.1 - 0.089 12.9 3.9 4 7.8 0.4 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.29 EMD00860.1 - 5.9e-19 68.8 0.0 9.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EMD00860.1 - 2.4e-05 24.8 0.1 7.5e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EMD00860.1 - 0.0015 18.8 0.1 0.0053 17.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain Hydin_ADK PF17213.3 EMD00860.1 - 0.0053 17.1 0.1 0.0088 16.3 0.1 1.3 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_5 PF07728.14 EMD00860.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EMD00860.1 - 0.019 14.7 0.3 0.05 13.3 0.1 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EMD00860.1 - 0.037 14.2 0.1 0.19 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 EMD00860.1 - 0.049 13.3 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_18 PF13238.6 EMD00860.1 - 0.12 12.9 0.1 0.31 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain Env-gp36 PF09590.10 EMD00862.1 - 0.11 11.0 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein Abhydrolase_1 PF00561.20 EMD00863.1 - 3.6e-14 53.0 0.0 8.1e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EMD00863.1 - 6.3e-12 45.3 0.0 2.3e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EMD00863.1 - 3.1e-11 44.3 0.0 4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EMD00863.1 - 0.00052 20.2 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 EMD00863.1 - 0.00088 18.8 0.0 0.82 9.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 EMD00863.1 - 0.0023 17.6 0.0 0.0049 16.6 0.0 1.7 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EMD00863.1 - 0.0049 16.6 0.1 0.0097 15.6 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein DLH PF01738.18 EMD00863.1 - 0.0082 15.7 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EMD00863.1 - 0.039 13.8 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 EMD00863.1 - 0.052 13.5 0.0 2.4 8.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 EMD00863.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.18 EMD00865.1 - 1.7e-27 96.1 0.0 3.7e-27 95.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD00865.1 - 1e-09 38.3 12.3 1.8e-09 37.5 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Luteo_PO PF04662.13 EMD00865.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Luteovirus P0 protein Beta_elim_lyase PF01212.21 EMD00868.1 - 4.7e-27 95.0 0.0 5.9e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EMD00868.1 - 0.0012 18.3 0.1 0.0069 15.7 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ank_4 PF13637.6 EMD00869.1 - 4.1e-27 94.2 12.1 2.8e-10 40.5 1.1 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMD00869.1 - 4.1e-26 91.4 4.1 3.9e-10 40.2 0.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMD00869.1 - 1.9e-17 63.1 7.7 6.2e-07 29.6 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMD00869.1 - 1.9e-17 61.5 8.5 0.00021 21.5 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EMD00869.1 - 2.2e-17 62.6 15.8 1.1e-05 25.7 0.1 5.9 6 0 0 6 6 6 5 Ankyrin repeat PH PF00169.29 EMD00874.1 - 0.026 15.0 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 PH domain Amidohydro_3 PF07969.11 EMD00876.1 - 2.6e-16 60.2 2.7 5.3e-13 49.3 0.1 3.4 3 1 0 4 4 4 2 Amidohydrolase family Amidohydro_1 PF01979.20 EMD00876.1 - 9.8e-12 44.8 0.0 5.6e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase family DUF4131 PF13567.6 EMD00876.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ARL6IP6 PF15062.6 EMD00876.1 - 0.12 12.5 0.0 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix GST_N_3 PF13417.6 EMD00878.1 - 6.5e-15 55.3 0.0 1.7e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMD00878.1 - 6.3e-13 48.8 0.0 1.7e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMD00878.1 - 3.1e-10 40.2 0.0 6.5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMD00878.1 - 2.7e-05 24.1 0.1 5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EMD00878.1 - 0.0005 20.2 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 EMD00878.1 - 0.0032 17.6 0.1 0.0054 16.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMD00878.1 - 0.016 15.8 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMD00878.1 - 0.05 13.8 0.1 0.09 13.0 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M41 PF01434.18 EMD00879.1 - 9.7e-67 224.5 0.1 2.4e-66 223.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EMD00879.1 - 4e-42 143.8 0.0 9.4e-42 142.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMD00879.1 - 1.4e-14 53.6 0.1 4e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EMD00879.1 - 6.7e-07 29.6 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 EMD00879.1 - 0.0005 20.1 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EMD00879.1 - 0.0059 16.9 0.1 1.2 9.4 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EMD00879.1 - 0.0061 17.0 1.4 0.24 11.8 0.2 3.0 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 EMD00879.1 - 0.0092 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EMD00879.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EMD00879.1 - 0.079 13.1 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EMD00879.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein MRI PF15325.6 EMD00879.1 - 8.5 7.5 7.6 6.9 7.8 1.3 2.8 2 0 0 2 2 2 0 Modulator of retrovirus infection Polyketide_cyc2 PF10604.9 EMD00880.1 - 0.00017 21.9 0.3 0.0002 21.7 0.3 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Amidohydro_1 PF01979.20 EMD00881.1 - 2.1e-24 86.5 0.0 3.1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EMD00881.1 - 8.6e-22 78.2 0.4 1.4e-10 41.3 0.0 3.1 2 1 1 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 EMD00881.1 - 0.024 14.9 0.2 0.048 14.0 0.2 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain GST_N_3 PF13417.6 EMD00882.1 - 0.0038 17.6 0.0 0.0081 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMD00882.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short PF00106.25 EMD00883.1 - 1.8e-40 138.5 0.1 2.6e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMD00883.1 - 4.1e-29 101.8 0.0 6e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMD00883.1 - 1.4e-09 38.1 0.6 4.6e-09 36.4 0.6 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EMD00883.1 - 0.00041 19.8 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EMD00883.1 - 0.00075 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0146 PF03686.13 EMD00883.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) DUF4159 PF13709.6 EMD00883.1 - 0.15 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Sds3 PF08598.11 EMD00884.1 - 3.1e-29 102.5 0.2 4.8e-29 101.9 0.2 1.4 1 0 0 1 1 1 1 Sds3-like CENP-H PF05837.12 EMD00884.1 - 0.5 10.8 4.2 1.6 9.2 4.2 1.9 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF1053 PF06327.14 EMD00884.1 - 7.2 7.2 5.7 2 9.0 0.5 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) EPSP_synthase PF00275.20 EMD00886.1 - 1.7e-122 409.1 0.0 2.5e-122 408.6 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EMD00886.1 - 1.7e-99 332.3 0.0 2.8e-99 331.5 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EMD00886.1 - 4.8e-56 190.6 0.0 1e-55 189.5 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EMD00886.1 - 9.3e-36 123.3 0.0 9.7e-35 120.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EMD00886.1 - 3.7e-24 84.8 0.0 9.8e-24 83.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EMD00886.1 - 1.6e-07 31.0 0.6 3.5e-07 29.9 0.6 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 EMD00886.1 - 0.00013 21.8 0.0 0.00044 20.0 0.0 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EMD00886.1 - 0.088 12.9 0.0 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 EMD00887.1 - 4.3e-61 207.1 0.0 5.5e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GGACT PF06094.12 EMD00888.1 - 4.6e-08 33.7 0.0 6.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EMD00888.1 - 2.3e-07 31.1 0.0 3.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Rav1p_C PF12234.8 EMD00889.1 - 3.3e-149 498.3 0.0 6.9e-149 497.2 0.0 1.4 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 EMD00889.1 - 0.0018 19.1 5.2 0.24 12.4 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat adh_short_C2 PF13561.6 EMD00890.1 - 5.6e-38 130.8 5.8 9.4e-37 126.8 5.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMD00890.1 - 1.2e-30 106.5 5.3 5.4e-30 104.3 5.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMD00890.1 - 8.9e-09 35.5 3.3 2.8e-08 33.9 3.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMD00890.1 - 0.0027 17.2 1.1 0.0031 17.0 0.4 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Tubulin PF00091.25 EMD00891.1 - 1.8e-68 230.6 0.0 9.1e-68 228.3 0.0 1.9 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EMD00891.1 - 1e-42 145.2 0.0 1.7e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EMD00891.1 - 4.3e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EMD00891.1 - 0.0035 17.0 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EMD00891.1 - 0.0047 16.2 0.0 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Tubulin like CwfJ_C_2 PF04676.14 EMD00894.1 - 4e-28 98.2 0.3 1.3e-27 96.6 0.3 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EMD00894.1 - 3.8e-27 94.6 0.0 5.7e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 ATP_bind_1 PF03029.17 EMD00895.1 - 1.8e-66 224.3 0.0 3.1e-66 223.6 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EMD00895.1 - 2.5e-05 23.9 0.0 0.0043 16.6 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EMD00895.1 - 0.00016 21.7 0.0 0.00059 19.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 EMD00895.1 - 0.00018 20.6 0.1 0.028 13.4 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EMD00895.1 - 0.00019 21.4 0.0 0.18 11.7 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EMD00895.1 - 0.00046 20.5 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EMD00895.1 - 0.0006 19.8 0.0 0.0014 18.6 0.0 1.6 2 0 0 2 2 1 1 NACHT domain Ras PF00071.22 EMD00895.1 - 0.0027 17.3 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EMD00895.1 - 0.0049 17.1 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EMD00895.1 - 0.0067 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EMD00895.1 - 0.008 16.6 0.0 0.025 15.0 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EMD00895.1 - 0.0084 16.3 0.1 0.031 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EMD00895.1 - 0.0086 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 EMD00895.1 - 0.012 15.2 0.1 0.31 10.6 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B PduV-EutP PF10662.9 EMD00895.1 - 0.015 15.0 0.1 0.095 12.4 0.0 2.3 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EMD00895.1 - 0.02 14.3 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EMD00895.1 - 0.021 14.0 0.1 0.79 8.8 0.0 2.5 2 1 0 2 2 2 0 G-protein alpha subunit TsaE PF02367.17 EMD00895.1 - 0.041 13.9 0.1 0.1 12.6 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EMD00895.1 - 0.045 14.3 1.2 0.27 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EMD00895.1 - 0.051 13.2 0.2 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase cobW PF02492.19 EMD00895.1 - 0.078 12.6 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 EMD00895.1 - 0.085 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EMD00895.1 - 0.093 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMD00895.1 - 0.098 12.3 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EMD00895.1 - 0.15 12.5 0.1 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Elongin_A PF06881.11 EMD00896.1 - 0.0082 16.6 0.3 0.015 15.8 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 EMD00896.1 - 0.054 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box domain Cation_ATPase_C PF00689.21 EMD00897.1 - 1.1e-50 171.8 7.0 1.1e-50 171.8 7.0 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EMD00897.1 - 7.5e-37 126.6 0.6 7.5e-37 126.6 0.6 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EMD00897.1 - 1.6e-23 82.6 0.0 4.3e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EMD00897.1 - 9.5e-20 71.8 0.2 2.2e-19 70.6 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EMD00897.1 - 1.7e-09 37.3 0.2 1.8e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EMD00897.1 - 0.0006 19.6 0.3 0.00099 18.9 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 EMD00897.1 - 0.00099 18.0 0.7 0.076 11.9 1.5 2.3 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG RskA PF10099.9 EMD00897.1 - 0.021 15.1 6.2 0.67 10.2 0.1 4.1 3 1 0 3 3 3 0 Anti-sigma-K factor rskA HD PF01966.22 EMD00898.1 - 4.2e-08 33.5 0.2 9.9e-08 32.2 0.1 1.7 1 1 1 2 2 2 1 HD domain 14-3-3 PF00244.20 EMD00901.1 - 2.4e-07 30.5 0.0 4.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 14-3-3 protein DGF-1_4 PF11024.8 EMD00901.1 - 0.14 13.0 2.6 37 5.2 0.0 3.4 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 HgmA PF04209.13 EMD00903.1 - 5.4e-202 671.1 0.1 6.2e-202 670.9 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 EMD00904.1 - 1.8e-52 178.2 0.0 2.3e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EMD00904.1 - 1.3e-30 105.7 0.0 2.3e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal DUF3659 PF12396.8 EMD00904.1 - 0.13 12.2 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) p450 PF00067.22 EMD00905.1 - 7.7e-59 199.6 0.0 8.8e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2615 PF11027.8 EMD00905.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Ribosomal_L2_C PF03947.18 EMD00906.1 - 2.4e-50 169.9 3.6 2.4e-50 169.9 3.6 2.4 3 0 0 3 3 3 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EMD00906.1 - 2.3e-23 82.0 0.7 5.6e-23 80.7 0.7 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 EMD00907.1 - 3.5e-46 156.1 0.1 6.7e-45 151.9 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EMD00907.1 - 3.3e-34 117.5 0.0 5.7e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Fungal_trans PF04082.18 EMD00908.1 - 3.3e-18 65.7 0.1 8.8e-18 64.3 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD00908.1 - 8e-09 35.5 8.6 1.5e-08 34.6 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MASE1 PF05231.14 EMD00909.1 - 0.0084 15.3 0.3 0.0093 15.1 0.3 1.1 1 0 0 1 1 1 1 MASE1 DUF3675 PF12428.8 EMD00909.1 - 2.6 8.6 5.8 3.5 8.2 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) Zn_clus PF00172.18 EMD00910.1 - 4.4e-08 33.1 10.7 6.7e-08 32.5 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 EMD00911.1 - 7.5e-55 185.0 0.0 1e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EMD00911.1 - 5.1e-15 55.3 0.0 6.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EMD00911.1 - 1.2e-05 25.6 0.1 1.8e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase p450 PF00067.22 EMD00912.1 - 1e-62 212.4 0.0 1.4e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 EMD00914.1 - 7.1e-24 83.6 19.3 4.9e-06 27.2 0.3 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMD00914.1 - 1.8e-12 47.3 4.8 1.1e-05 25.6 0.0 4.7 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EMD00914.1 - 0.00011 22.2 6.6 0.024 14.6 2.9 3.2 2 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 EMD00914.1 - 0.029 13.4 0.6 9.5 5.1 0.0 3.3 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nefa_Nip30_N PF10187.9 EMD00916.1 - 3.6e-34 117.3 7.5 8.5e-34 116.1 7.5 1.7 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 UVR PF02151.19 EMD00916.1 - 0.009 15.7 1.9 0.009 15.7 1.9 2.2 2 0 0 2 2 2 1 UvrB/uvrC motif Golgin_A5 PF09787.9 EMD00916.1 - 0.077 12.5 6.6 0.11 12.0 6.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 LCD1 PF09798.9 EMD00916.1 - 2.4 6.6 6.4 3.1 6.2 6.4 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF883 PF05957.13 EMD00916.1 - 3.4 8.3 9.2 0.77 10.4 3.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Aldo_ket_red PF00248.21 EMD00917.1 - 3.6e-48 164.3 0.0 1.9e-46 158.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family AdoHcyase PF05221.17 EMD00919.1 - 2.3e-123 411.1 0.0 2.3e-117 391.4 0.0 3.0 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EMD00919.1 - 1.6e-83 278.6 2.1 2.7e-83 277.9 2.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMD00919.1 - 1.6e-07 30.8 0.2 3.4e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EMD00919.1 - 0.0012 18.4 0.2 0.002 17.7 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EMD00919.1 - 0.0055 17.0 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 EMD00919.1 - 0.079 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ABC_tran PF00005.27 EMD00921.1 - 4.9e-47 159.9 1.7 6.4e-22 78.5 0.1 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EMD00921.1 - 2.6e-20 72.2 5.5 2.6e-20 72.2 5.5 3.1 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EMD00921.1 - 4.5e-14 53.0 3.8 0.0057 16.5 0.2 4.6 4 1 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EMD00921.1 - 3.4e-09 36.5 0.9 0.079 12.4 0.0 4.4 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EMD00921.1 - 2.7e-05 23.8 0.3 0.15 11.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EMD00921.1 - 3.1e-05 23.9 0.1 0.042 13.7 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EMD00921.1 - 3.3e-05 24.0 0.9 0.045 13.8 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EMD00921.1 - 6.9e-05 23.1 0.3 0.61 10.4 0.0 3.2 4 1 0 4 4 2 2 AAA domain AAA_23 PF13476.6 EMD00921.1 - 8e-05 23.2 20.3 0.012 16.1 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 EMD00921.1 - 0.00013 21.7 0.0 0.021 14.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EMD00921.1 - 0.00022 21.8 3.5 0.34 11.4 0.0 3.8 5 0 0 5 5 3 2 AAA domain AAA_24 PF13479.6 EMD00921.1 - 0.00025 20.8 1.6 0.72 9.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EMD00921.1 - 0.00028 21.3 2.2 0.05 14.0 0.2 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 EMD00921.1 - 0.00036 20.7 0.0 1.4 9.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EMD00921.1 - 0.0011 18.6 0.4 2.4 7.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 EMD00921.1 - 0.0014 18.6 0.1 0.88 9.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 EMD00921.1 - 0.0014 18.9 3.7 0.11 12.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 EMD00921.1 - 0.0024 18.3 0.1 2.2 8.7 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EMD00921.1 - 0.0064 16.9 0.0 3.6 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 EMD00921.1 - 0.012 15.6 0.0 8 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EMD00921.1 - 0.016 14.2 3.9 2.5 7.0 0.1 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 EMD00921.1 - 0.02 14.8 1.7 5.1 7.0 0.0 3.3 2 1 1 3 3 3 0 Rad17 P-loop domain AAA_15 PF13175.6 EMD00921.1 - 0.024 14.3 16.2 0.41 10.3 0.0 4.6 4 1 0 4 4 4 0 AAA ATPase domain NTPase_1 PF03266.15 EMD00921.1 - 0.035 14.0 0.1 3.2 7.7 0.0 2.7 2 0 0 2 2 2 0 NTPase cobW PF02492.19 EMD00921.1 - 0.041 13.5 0.6 4.2 6.9 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EMD00921.1 - 0.059 13.6 0.1 3.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 EMD00921.1 - 0.077 13.0 0.3 9.8 6.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EMD00921.1 - 0.089 12.4 0.2 4.5 6.8 0.1 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EMD00921.1 - 0.1 11.9 2.3 6.8 5.9 0.1 3.0 3 0 0 3 3 3 0 Zeta toxin MobB PF03205.14 EMD00921.1 - 0.11 12.4 0.4 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 EMD00921.1 - 0.11 11.6 0.6 7.4 5.7 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain ATP-synt_ab PF00006.25 EMD00921.1 - 0.14 11.8 0.0 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 EMD00921.1 - 7.9 6.9 8.1 49 4.4 0.2 3.8 4 0 0 4 4 3 0 AAA domain YchF-GTPase_C PF06071.13 EMD00922.1 - 3.9e-33 113.5 0.2 1.3e-32 111.8 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EMD00922.1 - 4.8e-15 55.6 0.0 1.2e-14 54.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EMD00922.1 - 0.0038 16.8 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EMD00922.1 - 0.011 15.8 0.1 0.044 13.8 0.1 2.1 3 0 0 3 3 3 0 TGS domain Ank_5 PF13857.6 EMD00923.1 - 2.1e-17 62.9 0.6 4.5e-11 42.8 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) VPS9 PF02204.18 EMD00923.1 - 2.7e-16 59.7 0.0 6.6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 EMD00923.1 - 6.1e-14 52.4 0.0 1.4e-05 25.6 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMD00923.1 - 1.6e-06 28.0 0.1 7 7.6 0.0 6.0 5 1 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EMD00923.1 - 6.1e-05 23.3 0.1 1.4 9.5 0.2 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EMD00923.1 - 0.00011 22.7 0.4 4.2 8.1 0.0 4.8 4 2 2 6 6 6 3 Ankyrin repeats (many copies) HD PF01966.22 EMD00925.1 - 3.9e-07 30.3 2.3 5.8e-06 26.5 1.2 2.2 2 0 0 2 2 2 1 HD domain DUF3652 PF12372.8 EMD00925.1 - 0.022 14.6 0.0 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 Huntingtin protein region OmdA PF13376.6 EMD00925.1 - 0.048 13.7 1.5 0.048 13.7 1.5 2.1 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Ribosomal_S11 PF00411.19 EMD00926.1 - 0.021 15.3 0.3 0.05 14.0 0.1 1.8 2 1 0 2 2 2 0 Ribosomal protein S11 Tim44 PF04280.15 EMD00927.1 - 5.9e-36 123.8 0.0 1.4e-35 122.5 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain DUF3391 PF11871.8 EMD00927.1 - 0.058 13.9 2.4 0.17 12.5 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3474 PF11960.8 EMD00927.1 - 0.086 13.0 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) CHCH PF06747.13 EMD00928.1 - 2.5e-08 33.8 2.1 3.6e-08 33.3 2.1 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 EMD00928.1 - 0.00079 19.7 3.6 0.0027 18.0 3.7 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EMD00928.1 - 0.0072 16.3 2.9 0.012 15.6 2.9 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 EMD00928.1 - 0.027 14.8 5.6 0.24 11.8 0.3 2.7 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 EMD00928.1 - 0.051 13.8 2.5 2 8.7 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) HLH PF00010.26 EMD00929.1 - 1.2e-11 44.4 0.2 5.5e-11 42.3 0.2 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain HrpA_pilin PF09589.10 EMD00929.1 - 4.8 8.0 6.4 13 6.6 0.1 2.6 2 1 0 2 2 2 0 HrpA pilus formation protein Got1 PF04178.12 EMD00930.1 - 1.4e-34 118.9 13.0 1.8e-34 118.5 13.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2632 PF10943.8 EMD00930.1 - 0.68 9.5 9.3 0.95 9.0 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) DUF2070 PF09843.9 EMD00930.1 - 0.7 8.1 6.5 0.88 7.8 6.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CFEM PF05730.11 EMD00931.1 - 3.8e-09 36.5 9.0 7.9e-09 35.5 9.0 1.6 1 0 0 1 1 1 1 CFEM domain Vac_ImportDeg PF09783.9 EMD00932.1 - 6.5e-67 224.4 0.1 8.1e-67 224.1 0.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mito_carr PF00153.27 EMD00933.1 - 1.7e-42 143.2 1.4 8.5e-16 57.7 1.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EMD00933.1 - 0.018 14.2 0.4 0.14 11.2 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease SLD3 PF08639.10 EMD00935.1 - 4.9e-140 467.8 17.5 6.7e-140 467.4 17.5 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 MFS_1 PF07690.16 EMD00938.1 - 5.7e-42 143.9 39.3 6.9e-41 140.3 36.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMD00938.1 - 6.2e-10 38.5 30.2 5.9e-09 35.3 30.2 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EMD00938.1 - 9.1e-10 37.6 0.9 1.6e-09 36.8 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EMD00938.1 - 1.6e-06 27.6 0.6 3.7e-06 26.5 0.6 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Complex1_LYR PF05347.15 EMD00939.1 - 2.3e-05 24.4 1.7 2.3e-05 24.4 1.7 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EMD00939.1 - 0.1 13.3 4.9 0.49 11.2 4.9 2.0 1 1 0 1 1 1 0 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EMD00939.1 - 0.11 13.1 2.5 0.17 12.5 1.7 1.8 1 1 1 2 2 2 0 Complex1_LYR-like DOR PF14839.6 EMD00939.1 - 0.15 12.0 1.0 0.16 11.9 1.0 1.2 1 0 0 1 1 1 0 DOR family PEMT PF04191.13 EMD00940.1 - 7.2e-35 119.6 2.6 7.6e-35 119.5 1.3 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Aa_trans PF01490.18 EMD00941.1 - 1.1e-25 90.2 33.9 1.3e-25 90.0 33.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein S1FA PF04689.13 EMD00941.1 - 4.7 7.4 5.6 1.1 9.4 1.3 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA Tudor_3 PF18115.1 EMD00943.1 - 0.053 13.4 3.5 4.2 7.3 0.1 3.2 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain MFS_1 PF07690.16 EMD00944.1 - 1.3e-36 126.2 37.3 1.3e-36 126.2 37.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EMD00945.1 - 2.8e-28 98.9 56.3 2.7e-25 89.1 30.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMD00945.1 - 3.5e-18 65.7 19.4 9.7e-18 64.3 19.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter HLH PF00010.26 EMD00946.1 - 8.1e-14 51.3 0.4 1.4e-13 50.6 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tombus_movement PF05318.12 EMD00946.1 - 5.5 7.9 5.9 2.2 9.2 2.0 2.2 2 0 0 2 2 2 0 Tombusvirus movement protein HCO3_cotransp PF00955.21 EMD00948.1 - 9.3e-70 235.9 8.7 5.8e-39 134.3 4.1 2.6 1 1 1 2 2 2 2 HCO3- transporter family Alliinase_C PF04864.13 EMD00949.1 - 0.17 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Allinase SUZ PF12752.7 EMD00950.1 - 0.00057 20.6 11.1 0.00057 20.6 11.1 3.5 2 1 1 3 3 3 1 SUZ domain DUF1509 PF07420.11 EMD00950.1 - 0.19 10.7 9.3 0.24 10.3 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Tho2 PF11262.8 EMD00950.1 - 0.72 9.0 2.4 1 8.5 2.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 U1snRNP70_N PF12220.8 EMD00950.1 - 4.6 7.9 10.8 4 8.2 4.8 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PXA PF02194.15 EMD00952.1 - 4.2e-45 154.0 0.1 2.7e-44 151.3 0.1 2.5 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EMD00952.1 - 1.5e-25 90.0 0.1 1.2e-24 87.0 0.0 2.7 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 EMD00952.1 - 3.1e-21 75.5 0.3 6.5e-21 74.4 0.3 1.5 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EMD00952.1 - 5.5e-10 39.6 0.0 3.5e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain ABC_tran_CTD PF16326.5 EMD00952.1 - 3.6 7.9 10.6 0.34 11.2 3.8 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain tRNA-synt_2b PF00587.25 EMD00953.1 - 2.3e-37 128.7 0.0 4e-37 127.9 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EMD00953.1 - 3.5e-13 49.5 0.0 7.6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.17 EMD00954.1 - 5.1e-55 186.1 0.1 1.2e-54 184.9 0.1 1.7 1 0 0 1 1 1 1 CBF/Mak21 family BUD22 PF09073.10 EMD00954.1 - 0.00021 20.8 12.7 0.00021 20.8 12.7 1.7 2 0 0 2 2 2 1 BUD22 Adaptin_N PF01602.20 EMD00954.1 - 0.0004 19.1 4.9 0.0019 16.8 0.2 2.5 2 1 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 EMD00954.1 - 0.0026 17.8 1.0 0.0047 17.0 0.1 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 IATP PF04568.12 EMD00954.1 - 0.036 14.5 0.8 0.036 14.5 0.8 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DNA_alkylation PF08713.11 EMD00954.1 - 0.14 11.9 0.9 5.2 6.7 0.2 3.0 3 0 0 3 3 3 0 DNA alkylation repair enzyme Rox3 PF08633.10 EMD00955.1 - 6.9e-49 166.9 0.7 1.4e-48 165.9 0.0 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit Na_H_Exchanger PF00999.21 EMD00956.1 - 5.3e-26 91.3 35.2 1.1e-21 77.1 23.6 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family DUF5367 PF17329.2 EMD00956.1 - 0.025 14.7 0.3 0.098 12.8 0.3 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5367) Rad10 PF03834.14 EMD00957.1 - 4.3e-47 158.8 0.0 5.9e-47 158.4 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EMD00957.1 - 0.00041 20.9 0.0 0.0008 20.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain PfUIS3 PF11567.8 EMD00957.1 - 0.086 13.2 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein Zn_clus PF00172.18 EMD00958.1 - 3e-11 43.3 7.9 3e-11 43.3 7.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.12 EMD00959.1 - 4.1e-101 338.3 5.2 5.4e-101 337.9 5.2 1.1 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EMD00959.1 - 5.5e-22 77.7 6.7 1.2e-10 41.8 0.3 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMD00959.1 - 5.9e-10 39.3 0.0 2.9e-06 27.5 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EMD00959.1 - 0.05 13.5 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nop53 PF07767.11 EMD00959.1 - 0.1 12.0 0.3 0.19 11.1 0.1 1.4 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Fungal_trans PF04082.18 EMD00960.1 - 4.2e-10 39.1 0.3 6.2e-10 38.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EMD00961.1 - 8.2e-18 64.4 0.1 1.5e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD00961.1 - 3.9e-06 26.9 2.4 6.6e-06 26.2 2.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2397 PF09660.10 EMD00961.1 - 0.048 12.6 0.2 0.078 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Acyl-CoA_dh_1 PF00441.24 EMD00962.1 - 4.2e-34 117.9 3.7 5.9e-34 117.4 3.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMD00962.1 - 1.2e-24 86.3 0.1 2.7e-24 85.2 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMD00962.1 - 1.4e-12 48.2 0.0 5.1e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMD00962.1 - 1.7e-08 34.8 1.1 2.4e-08 34.3 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Trs65 PF12735.7 EMD00963.1 - 1.7e-21 77.0 1.0 1.1e-18 67.8 1.0 3.0 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 UQ_con PF00179.26 EMD00964.1 - 3.4e-19 68.9 0.0 3.6e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EMD00964.1 - 0.015 15.5 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain 4HBT PF03061.22 EMD00965.1 - 8.3e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Glyco_hydro_6 PF01341.17 EMD00967.1 - 3.5e-105 352.1 0.7 4.6e-105 351.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 EMD00967.1 - 1.5e-06 28.1 15.9 1.5e-06 28.1 15.9 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain SnoaL_4 PF13577.6 EMD00968.1 - 3.8e-17 62.6 0.0 4.8e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF2256 PF10013.9 EMD00969.1 - 0.00022 21.3 2.8 0.00086 19.4 2.8 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYND PF01753.18 EMD00969.1 - 0.18 11.9 3.4 0.39 10.8 3.4 1.5 1 0 0 1 1 1 0 MYND finger Metallophos PF00149.28 EMD00970.1 - 7.7e-11 42.9 0.8 2.2e-10 41.4 0.8 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HET PF06985.11 EMD00971.1 - 6e-23 81.8 0.1 8.7e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PGK PF00162.19 EMD00972.1 - 4.4e-151 503.1 0.3 5e-151 502.9 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 EMD00972.1 - 0.0015 18.5 0.4 0.052 13.6 0.0 2.9 3 0 0 3 3 3 1 PA domain Acetyltransf_CG PF14542.6 EMD00972.1 - 0.045 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Aminotran_4 PF01063.19 EMD00974.1 - 3e-27 96.0 0.0 4.1e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 EMD00975.1 - 1.9e-72 244.5 0.0 2.6e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EMD00975.1 - 1.3e-31 109.9 0.0 2.7e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EMD00975.1 - 4e-24 85.5 1.1 7.6e-24 84.5 0.1 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EMD00975.1 - 3.8e-14 53.2 0.0 1.2e-13 51.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EMD00975.1 - 0.00094 19.3 0.0 0.16 12.1 0.0 3.1 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Flavodoxin_5 PF12724.7 EMD00975.1 - 0.0046 17.2 0.0 0.0096 16.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Mpv17_PMP22 PF04117.12 EMD00976.1 - 3.6e-19 68.7 0.4 9.1e-19 67.5 0.4 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family HisKA_4TM PF16926.5 EMD00976.1 - 0.001 18.7 0.2 0.0016 18.0 0.2 1.2 1 0 0 1 1 1 1 Archaeal 4TM region of histidine kinase Asn_synthase PF00733.21 EMD00977.1 - 2.1e-15 57.3 0.0 9.7e-06 25.5 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase Pro_CA PF00484.19 EMD00978.1 - 1.5e-10 41.5 3.3 3e-09 37.4 3.3 2.1 1 1 0 1 1 1 1 Carbonic anhydrase Glutaredoxin PF00462.24 EMD00979.1 - 4.3e-15 55.7 0.0 7.5e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.20 EMD00979.1 - 0.031 14.1 0.1 2.8 7.7 0.1 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.6 EMD00979.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Ribosomal_L6 PF00347.23 EMD00980.1 - 8.4e-28 96.9 3.3 6.6e-13 49.1 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 LSM PF01423.22 EMD00983.1 - 1.3e-17 63.2 0.3 2.1e-17 62.6 0.1 1.4 2 0 0 2 2 2 1 LSM domain FF PF01846.19 EMD00984.1 - 4.6e-38 129.2 11.4 1.9e-10 40.8 1.8 6.1 6 0 0 6 6 6 4 FF domain RhoGAP-FF1 PF16512.5 EMD00984.1 - 2.4e-05 24.9 15.4 0.18 12.5 0.2 5.2 2 1 2 4 4 4 4 p190-A and -B Rho GAPs FF domain WW PF00397.26 EMD00984.1 - 0.0027 17.8 12.3 0.081 13.0 1.6 3.5 2 1 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 EMD00984.1 - 0.27 11.5 4.1 4 7.8 0.4 2.8 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain DUF4865 PF16157.5 EMD00985.1 - 0.12 12.4 0.3 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) ABC_tran PF00005.27 EMD00986.1 - 5.9e-24 85.1 0.0 1.4e-15 58.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EMD00986.1 - 3.1e-10 39.9 0.9 0.004 16.6 0.0 3.1 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EMD00986.1 - 1.1e-05 25.4 0.2 1.5 8.6 0.0 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 EMD00986.1 - 0.00013 20.8 0.0 0.00029 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EMD00986.1 - 0.0018 18.6 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EMD00986.1 - 0.0082 16.6 0.2 0.033 14.6 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EMD00986.1 - 0.0089 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain PduV-EutP PF10662.9 EMD00986.1 - 0.018 14.8 0.1 0.057 13.2 0.1 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EMD00986.1 - 0.02 14.9 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EMD00986.1 - 0.029 14.1 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMD00986.1 - 0.045 13.4 0.1 0.076 12.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 EMD00986.1 - 0.058 12.9 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EMD00986.1 - 0.059 13.8 0.0 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 EMD00986.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EMD00986.1 - 0.084 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 EMD00986.1 - 0.097 12.4 0.1 0.83 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 EMD00986.1 - 0.11 11.9 0.2 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 EMD00986.1 - 0.12 12.9 0.8 0.29 11.6 0.8 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EMD00986.1 - 0.12 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DLIC PF05783.11 EMD00986.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Rad51 PF08423.11 EMD00986.1 - 0.18 11.0 0.3 1.3 8.3 0.1 2.0 2 0 0 2 2 2 0 Rad51 SNF2_N PF00176.23 EMD00989.1 - 4.2e-57 193.4 0.0 7e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EMD00989.1 - 4.5e-19 68.1 7.7 1.8e-15 56.6 1.5 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EMD00989.1 - 1.9e-18 66.8 0.0 4.6e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 EMD00989.1 - 4.5e-16 59.1 0.2 4.5e-16 59.1 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 EMD00989.1 - 1.4e-06 27.7 0.0 4.4e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EMD00989.1 - 2.7e-06 27.5 0.0 1e-05 25.6 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 EMD00989.1 - 7.2e-05 23.1 18.8 0.00068 19.9 0.7 4.4 3 1 1 4 4 4 2 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 EMD00989.1 - 0.0034 17.4 0.3 0.029 14.4 0.0 2.8 3 1 1 4 4 4 1 SLIDE DNA_pol3_a_NII PF11490.8 EMD00989.1 - 0.06 13.2 4.3 0.059 13.3 2.1 2.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II CHDCT2 PF08074.11 EMD00989.1 - 0.081 13.1 0.0 0.35 11.0 0.0 2.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain S4 PF01479.25 EMD00989.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 S4 domain DUF3808 PF10300.9 EMD00990.1 - 2.8e-136 455.0 0.0 3.5e-136 454.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TruB_C PF09142.11 EMD00991.1 - 3e-06 26.9 0.2 0.084 12.7 0.0 3.4 3 0 0 3 3 3 2 tRNA Pseudouridine synthase II, C terminal F-box-like PF12937.7 EMD00991.1 - 6.1e-06 26.0 0.3 1.4e-05 24.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EMD00991.1 - 0.00041 20.1 0.0 0.00098 19.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain PD40 PF07676.12 EMD00991.1 - 0.037 14.0 0.0 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CIA30 PF08547.12 EMD00992.1 - 9.3e-38 129.8 0.0 1.2e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.21 EMD00993.1 - 1.1e-05 25.5 6.1 1.9e-05 24.6 6.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMD00993.1 - 5.3e-05 23.2 7.3 7.8e-05 22.7 7.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EMD00993.1 - 0.0074 16.8 6.2 0.013 16.0 6.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Zn_Tnp_IS1595 PF12760.7 EMD00995.1 - 0.021 14.8 0.2 0.037 14.0 0.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Methyltransf_11 PF08241.12 EMD00997.1 - 6.5e-18 65.2 0.0 2.5e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMD00997.1 - 1.1e-16 61.3 0.0 4.1e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMD00997.1 - 6.1e-13 48.8 0.0 1.3e-12 47.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EMD00997.1 - 1.3e-11 44.6 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMD00997.1 - 9.9e-10 39.1 0.0 2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMD00997.1 - 2.2e-06 27.2 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EMD00997.1 - 2.8e-05 23.5 0.0 4.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EMD00997.1 - 0.00012 21.7 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EMD00997.1 - 0.00066 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 EMD00997.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EMD00997.1 - 0.0036 17.3 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EMD00997.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 EMD00997.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 EMD00997.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.12 EMD00997.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DAO PF01266.24 EMD00998.1 - 7.1e-39 134.4 0.8 8.3e-39 134.2 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMD00998.1 - 0.00017 21.7 0.3 0.00065 19.9 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EMD00998.1 - 0.0015 17.8 0.1 0.003 16.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EMD00998.1 - 0.012 14.7 0.5 0.12 11.4 0.3 2.4 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_3 PF13738.6 EMD00998.1 - 0.13 11.5 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EMD00998.1 - 0.14 11.3 0.0 0.4 9.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LIP PF03583.14 EMD00999.1 - 0.044 13.1 0.1 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 Secretory lipase EHN PF06441.12 EMD01000.1 - 4.1e-32 110.8 0.2 2.1e-30 105.2 0.0 2.5 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EMD01000.1 - 4e-12 46.3 0.1 6.6e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMD01000.1 - 7.7e-05 23.4 2.2 7.7e-05 23.4 2.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family AP2 PF00847.20 EMD01000.1 - 0.19 12.0 0.5 28 5.0 0.0 3.2 3 0 0 3 3 3 0 AP2 domain Granulin PF00396.18 EMD01001.1 - 5.4 7.4 12.5 19 5.7 12.5 1.9 1 1 0 1 1 1 0 Granulin Aldo_ket_red PF00248.21 EMD01002.1 - 1.1e-65 221.7 0.0 1.4e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 EMD01004.1 - 4.4e-17 62.3 0.0 2.3e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD01004.1 - 8.5e-08 31.8 0.0 3.8e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase GPP34 PF05719.11 EMD01004.1 - 0.03 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Sas10 PF09368.10 EMD01006.1 - 9e-30 103.0 11.0 2.5e-29 101.5 7.9 2.8 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EMD01006.1 - 1.2e-12 48.3 0.1 3.9e-12 46.6 0.1 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF1471 PF07338.13 EMD01006.1 - 6.2 6.9 6.4 16 5.6 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1471) Alpha-amylase PF00128.24 EMD01007.1 - 4.6e-107 358.5 0.7 6.7e-107 357.9 0.1 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EMD01007.1 - 1.5e-06 28.2 0.0 4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EMD01007.1 - 8.2e-05 21.9 0.0 0.00033 19.9 0.0 1.8 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain NAD_binding_4 PF07993.12 EMD01008.1 - 1.6e-43 148.8 0.0 1.5e-41 142.3 0.0 2.5 3 0 0 3 3 3 2 Male sterility protein AMP-binding PF00501.28 EMD01008.1 - 2.1e-21 76.0 0.0 2.7e-18 65.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 EMD01008.1 - 3.8e-13 49.5 0.0 1.8e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EMD01008.1 - 0.00015 22.0 0.4 0.00049 20.4 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EMD01008.1 - 0.0039 16.6 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Acyl-CoA_dh_1 PF00441.24 EMD01009.1 - 3.5e-28 98.7 2.6 5.3e-28 98.1 2.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EMD01009.1 - 5.5e-23 81.0 0.0 9e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EMD01009.1 - 2e-20 73.5 0.0 5.8e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EMD01009.1 - 0.0024 18.2 1.1 0.0038 17.5 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain IBR PF01485.21 EMD01010.1 - 1.2e-09 38.3 3.7 1.2e-09 38.3 3.7 2.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain GP88 PF17338.2 EMD01010.1 - 0.068 12.6 0.6 8.3 5.8 0.4 2.8 3 0 0 3 3 3 0 Gene product 88 Pkinase PF00069.25 EMD01011.1 - 1.6e-68 231.0 0.0 2.7e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD01011.1 - 9.4e-38 130.0 0.0 1.6e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EMD01011.1 - 9.3e-05 21.9 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EMD01011.1 - 0.00057 19.9 0.0 0.0017 18.3 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EMD01011.1 - 0.0015 17.4 0.0 0.0032 16.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EMD01011.1 - 0.0021 17.2 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 TACC_C PF05010.14 EMD01011.1 - 0.037 13.8 1.3 0.11 12.2 1.3 1.8 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Kdo PF06293.14 EMD01011.1 - 0.043 13.2 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans_2 PF11951.8 EMD01012.1 - 7.8e-18 64.4 0.2 9.6e-17 60.9 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD01012.1 - 0.0051 16.9 1.1 0.0098 16.0 1.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EMD01013.1 - 7.4e-48 162.6 0.4 8.1e-48 162.5 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMD01013.1 - 1.3e-45 155.8 0.1 1.7e-45 155.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMD01013.1 - 3e-11 43.6 0.1 6e-11 42.6 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EMD01013.1 - 2.8e-06 27.0 0.1 3.3e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EMD01013.1 - 6.7e-05 23.1 0.1 9.8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EMD01013.1 - 0.00066 19.6 0.2 0.00092 19.1 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EMD01013.1 - 0.0028 17.8 0.8 0.0049 17.0 0.8 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 EMD01013.1 - 0.0029 17.8 0.2 0.0048 17.1 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 EMD01013.1 - 0.0083 16.7 0.2 0.014 15.9 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EMD01013.1 - 0.017 14.3 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_3 PF03447.16 EMD01013.1 - 0.022 15.4 0.1 0.031 14.9 0.1 1.1 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EMD01013.1 - 0.047 13.1 0.2 0.075 12.4 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EMD01013.1 - 0.078 12.3 0.4 0.13 11.6 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dak1 PF02733.17 EMD01014.1 - 4.5e-100 334.6 0.0 6.6e-100 334.0 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EMD01014.1 - 3.4e-35 121.5 3.0 3.4e-35 121.5 3.0 1.7 2 0 0 2 2 2 1 DAK2 domain F_bP_aldolase PF01116.20 EMD01015.1 - 1.5e-81 274.0 0.0 1.6e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CobS PF02654.15 EMD01015.1 - 0.12 12.5 0.2 1.8 8.7 0.0 2.0 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase adh_short_C2 PF13561.6 EMD01016.1 - 8.7e-50 169.4 0.1 1.1e-49 169.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMD01016.1 - 1.5e-45 155.1 0.8 1.8e-45 154.8 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMD01016.1 - 4.2e-12 46.4 0.1 6.4e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EMD01016.1 - 0.0014 17.8 0.1 0.0017 17.6 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EMD01016.1 - 0.0034 16.9 0.1 0.0049 16.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EMD01016.1 - 0.052 12.5 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 EMD01017.1 - 1.4e-37 129.5 29.2 1.4e-37 129.5 29.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Ammonium_transp PF00909.21 EMD01019.1 - 2e-119 398.8 31.7 2.3e-119 398.6 31.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RRM_1 PF00076.22 EMD01021.1 - 7.6e-09 35.3 0.2 0.00098 18.9 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.21 EMD01022.1 - 2.1e-62 211.0 0.0 2.6e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.6 EMD01023.1 - 3.3e-09 36.8 8.4 9.6e-08 32.1 1.0 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EMD01023.1 - 5.7e-07 29.6 10.3 8.4e-06 26.0 0.1 4.3 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EMD01023.1 - 1.3e-06 28.3 0.9 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EMD01023.1 - 6e-05 23.5 6.4 0.014 16.2 0.1 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 EMD01023.1 - 0.00038 21.0 8.4 0.025 15.2 0.0 3.4 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 EMD01023.1 - 0.0024 17.6 1.3 2.5 8.0 0.0 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 EMD01023.1 - 0.09 12.9 2.0 6.6 6.8 0.5 2.4 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 EMD01023.1 - 0.1 12.9 0.4 3.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 EMD01023.1 - 0.13 13.0 1.3 11 6.7 0.1 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zap1_zf2 PF18217.1 EMD01023.1 - 0.34 10.9 7.6 0.66 10.0 0.3 2.7 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf-Di19 PF05605.12 EMD01023.1 - 0.71 10.2 4.8 4.3 7.7 1.2 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3899 PF13038.6 EMD01024.1 - 0.069 13.7 0.1 0.069 13.7 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) COX4_pro PF03626.14 EMD01024.1 - 0.077 13.4 1.9 0.16 12.5 1.9 1.7 1 1 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV Nup160 PF11715.8 EMD01025.1 - 9.7e-77 258.8 0.1 1.2e-76 258.5 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 SopA PF13981.6 EMD01025.1 - 0.079 13.4 0.1 0.2 12.1 0.1 1.7 1 1 0 1 1 1 0 SopA-like central domain NPR3 PF03666.13 EMD01026.1 - 4.8e-88 296.0 0.2 1.4e-85 287.9 0.2 2.1 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 HTH_1 PF00126.27 EMD01026.1 - 0.094 12.7 0.5 0.29 11.1 0.5 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 EMD01026.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Mem_trans PF03547.18 EMD01028.1 - 5e-19 68.0 6.4 4.8e-18 64.7 6.4 1.9 1 1 0 1 1 1 1 Membrane transport protein K_trans PF02705.16 EMD01029.1 - 8.1e-187 622.0 15.2 1.1e-186 621.5 15.2 1.2 1 0 0 1 1 1 1 K+ potassium transporter SPC25 PF06703.11 EMD01029.1 - 0.79 9.5 3.3 9.1 6.0 0.1 2.9 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) HAD_2 PF13419.6 EMD01030.1 - 0.0022 18.1 0.0 0.0028 17.8 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EMD01030.1 - 0.0052 17.1 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GRP PF07172.11 EMD01033.1 - 0.002 18.8 1.4 0.0027 18.4 1.4 1.2 1 0 0 1 1 1 1 Glycine rich protein family DUF1180 PF06679.12 EMD01033.1 - 0.17 12.3 1.1 0.25 11.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mito_carr PF00153.27 EMD01034.1 - 1.3e-65 217.4 0.3 1.9e-22 79.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Nop PF01798.18 EMD01035.1 - 2.6e-71 239.7 0.1 3.4e-71 239.4 0.1 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EMD01035.1 - 1.6e-46 158.1 2.0 3.5e-46 157.0 2.0 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain AAR2 PF05282.11 EMD01036.1 - 0.3 10.5 1.7 0.34 10.2 1.7 1.1 1 0 0 1 1 1 0 AAR2 protein DEAD PF00270.29 EMD01037.1 - 2.9e-50 170.5 0.0 5e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMD01037.1 - 9.7e-25 87.1 0.0 3.1e-24 85.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EMD01037.1 - 4.5e-05 23.5 0.1 0.00024 21.1 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HEPN_AbiU2 PF18734.1 EMD01037.1 - 0.19 11.2 1.9 1.3 8.4 0.4 2.3 2 0 0 2 2 2 0 AbiU2 CMS1 PF14617.6 EMD01037.1 - 0.37 10.1 0.0 0.37 10.1 0.0 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF1501 PF07394.12 EMD01037.1 - 7.4 5.5 9.7 0.2 10.7 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) DUF1180 PF06679.12 EMD01039.1 - 0.00059 20.3 0.1 0.00059 20.3 0.1 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF1180) Kelch_6 PF13964.6 EMD01039.1 - 0.0094 16.2 1.8 0.49 10.8 0.1 3.8 4 0 0 4 4 4 1 Kelch motif stn_TNFRSF12A PF12191.8 EMD01039.1 - 0.094 12.9 0.2 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain adh_short_C2 PF13561.6 EMD01040.1 - 8.4e-61 205.5 0.5 1.2e-60 205.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMD01040.1 - 7.1e-53 179.0 2.3 8.2e-53 178.8 2.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMD01040.1 - 5.8e-18 65.4 1.0 7.5e-18 65.1 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMD01040.1 - 1.6e-07 31.1 0.9 7e-07 28.9 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMD01040.1 - 1.6e-06 27.5 0.7 1.9e-06 27.2 0.7 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EMD01040.1 - 7.2e-05 22.7 0.2 9.5e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EMD01040.1 - 0.0058 17.2 0.1 0.015 15.8 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 EMD01040.1 - 0.031 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 EMD01040.1 - 0.034 13.5 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cofilin_ADF PF00241.20 EMD01040.1 - 0.035 13.9 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Prenyltransf PF01255.19 EMD01040.1 - 0.1 12.1 0.3 0.26 10.8 0.2 1.6 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase p450 PF00067.22 EMD01041.1 - 4.5e-21 75.1 0.0 4.9e-19 68.4 0.0 2.8 2 1 0 2 2 2 1 Cytochrome P450 MFS_1 PF07690.16 EMD01042.1 - 4.8e-29 101.4 20.1 2.7e-27 95.6 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 EMD01042.1 - 2.1 8.6 11.4 1.5 9.1 1.2 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) HIT PF01230.23 EMD01043.1 - 3e-15 56.8 0.1 1.2e-14 54.8 0.0 1.9 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EMD01043.1 - 0.1 13.1 0.2 1.4 9.4 0.2 2.2 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Urease_beta PF00699.20 EMD01043.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Urease beta subunit DUF2989 PF11207.8 EMD01045.1 - 0.029 14.2 1.0 0.051 13.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) ZZ PF00569.17 EMD01045.1 - 0.037 13.8 2.5 0.09 12.6 2.5 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type MFS_1 PF07690.16 EMD01046.1 - 9.1e-16 57.7 33.7 9.1e-16 57.7 33.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1980 PF09323.10 EMD01046.1 - 0.094 12.6 0.2 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2811 PF10929.8 EMD01046.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) LapA_dom PF06305.11 EMD01046.1 - 4.6 7.1 6.9 2.8 7.8 0.2 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain 2H-phosphodiest PF08975.10 EMD01047.1 - 1.4e-24 86.3 0.0 2.4e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) 2_5_RNA_ligase2 PF13563.6 EMD01047.1 - 0.00078 19.4 0.0 0.0048 16.8 0.0 1.9 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily F-box_4 PF15966.5 EMD01048.1 - 4.2e-05 23.4 0.1 8.5e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 F-box F-box PF00646.33 EMD01048.1 - 0.029 14.3 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain Connexin PF00029.19 EMD01049.1 - 0.32 10.7 0.6 0.62 9.8 0.6 1.4 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 EMD01049.1 - 1.7 8.2 12.3 4.1 6.9 12.3 1.6 1 0 0 1 1 1 0 Spt20 family zf-C2H2 PF00096.26 EMD01050.1 - 2.4e-16 59.1 23.7 1.9e-05 24.8 0.3 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMD01050.1 - 4.4e-13 48.9 22.4 8.6e-05 23.1 0.4 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EMD01050.1 - 4.5e-13 49.0 21.6 2.2e-05 24.6 0.3 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EMD01050.1 - 1.9e-07 31.2 18.0 0.016 15.5 0.0 4.4 3 2 1 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EMD01050.1 - 8.4e-07 29.2 15.2 0.00018 21.7 3.1 2.8 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 EMD01050.1 - 1.4e-06 28.1 10.8 0.00021 21.2 0.2 3.6 3 1 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 EMD01050.1 - 6.9e-06 26.3 6.2 0.054 13.9 0.4 3.8 2 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 EMD01050.1 - 0.0019 18.0 2.5 0.2 11.5 0.1 3.0 2 1 1 3 3 3 1 C2H2 type zinc-finger (1 copy) FOXP-CC PF16159.5 EMD01050.1 - 0.0025 18.4 12.2 0.061 14.0 1.0 3.4 1 1 3 4 4 4 2 FOXP coiled-coil domain zf_UBZ PF18439.1 EMD01050.1 - 0.0064 16.1 0.9 2.7 7.7 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 EMD01050.1 - 0.0087 15.9 3.4 1.3 9.0 0.1 3.6 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-MYST PF17772.1 EMD01050.1 - 0.011 15.3 0.7 0.35 10.5 0.1 2.6 1 1 1 2 2 2 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 EMD01050.1 - 0.017 15.4 9.5 0.09 13.1 0.3 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FdhE PF04216.12 EMD01050.1 - 0.024 14.5 0.1 0.033 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF2256 PF10013.9 EMD01050.1 - 0.025 14.7 1.7 1.2 9.3 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Vps39_2 PF10367.9 EMD01050.1 - 0.032 14.7 2.2 0.59 10.6 0.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Zn-C2H2_12 PF18112.1 EMD01050.1 - 0.058 13.9 3.7 0.16 12.5 0.2 3.3 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain XPA_N PF01286.18 EMD01050.1 - 0.071 13.2 1.1 1.3 9.1 0.1 2.7 2 0 0 2 2 2 0 XPA protein N-terminal DUF3268 PF11672.8 EMD01050.1 - 0.11 12.8 2.8 0.48 10.8 0.5 2.1 1 1 1 2 2 2 0 zinc-finger-containing domain Cript PF10235.9 EMD01050.1 - 0.21 12.2 4.4 0.48 11.0 1.1 2.1 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT ADK_lid PF05191.14 EMD01050.1 - 0.79 9.8 6.4 0.17 11.9 2.1 2.1 1 1 1 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_9 PF14369.6 EMD01050.1 - 1 9.6 0.1 1 9.6 0.1 3.4 4 0 0 4 4 3 0 zinc-ribbon HMG_box_2 PF09011.10 EMD01052.1 - 4.1e-09 36.9 10.2 0.00012 22.6 0.8 3.4 1 1 2 3 3 3 2 HMG-box domain HMG_box PF00505.19 EMD01052.1 - 1.2e-07 32.1 12.8 0.00013 22.3 1.4 4.1 2 2 0 2 2 2 2 HMG (high mobility group) box UPF0020 PF01170.18 EMD01053.1 - 4.5e-09 36.3 0.1 1e-07 31.8 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EMD01053.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase MethyltransfD12 PF02086.15 EMD01053.1 - 0.15 11.7 0.2 0.49 10.0 0.0 1.8 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase PAF-AH_p_II PF03403.13 EMD01054.1 - 2.2e-49 168.0 0.0 5.9e-24 84.3 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EMD01054.1 - 1.4e-05 24.2 0.0 3.2e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EMD01054.1 - 0.0029 16.7 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 EMD01054.1 - 0.0033 16.7 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF4556 PF15094.6 EMD01054.1 - 0.06 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) DUF2293 PF10056.9 EMD01055.1 - 3.7e-22 78.4 0.1 8.5e-22 77.2 0.2 1.6 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2293) p450 PF00067.22 EMD01057.1 - 2.5e-62 211.2 0.0 3.2e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5470 PF17564.2 EMD01058.1 - 0.36 11.1 0.0 0.36 11.1 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5470) Aldedh PF00171.22 EMD01060.1 - 4.3e-103 345.3 0.0 5.2e-103 345.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 2-oxoacid_dh PF00198.23 EMD01061.1 - 5.1e-70 235.5 0.0 9.1e-70 234.7 0.0 1.4 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EMD01061.1 - 1.2e-18 66.7 0.1 3.5e-17 62.0 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EMD01061.1 - 8.5e-15 54.8 0.1 2.3e-14 53.5 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain BtrH_N PF14399.6 EMD01061.1 - 0.026 14.8 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Vps26 PF03643.15 EMD01062.1 - 8.7e-120 398.8 0.0 1e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EMD01062.1 - 0.017 15.2 0.2 2.5 8.2 0.0 2.9 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain DUF3500 PF12006.8 EMD01063.1 - 1.3e-90 304.0 0.0 1.5e-90 303.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Phage_30_3 PF08010.11 EMD01063.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 adh_short_C2 PF13561.6 EMD01064.1 - 2.8e-59 200.5 1.2 3.3e-59 200.3 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EMD01064.1 - 4e-41 140.6 1.6 5.2e-41 140.3 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EMD01064.1 - 1.3e-11 44.7 0.7 1.8e-11 44.3 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EMD01064.1 - 0.0013 18.3 1.5 0.16 11.4 0.2 2.4 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family S4 PF01479.25 EMD01064.1 - 0.093 12.5 0.0 0.3 10.8 0.0 1.9 1 0 0 1 1 1 0 S4 domain Ecm29 PF13001.7 EMD01065.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Proteasome stabiliser TPR_9 PF13371.6 EMD01065.1 - 0.61 10.3 9.1 1.5 9.0 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MOZART1 PF12554.8 EMD01066.1 - 1.1e-26 92.4 0.3 1.3e-26 92.1 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated TIP49_C PF17856.1 EMD01066.1 - 0.05 13.7 0.7 0.089 12.9 0.5 1.6 1 1 1 2 2 2 0 TIP49 AAA-lid domain Gryzun PF07919.12 EMD01067.1 - 2.5e-111 373.3 0.0 4.4e-111 372.5 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 EMD01067.1 - 1.6e-62 211.5 8.1 4.9e-59 200.0 5.6 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 Ank_5 PF13857.6 EMD01068.1 - 9.1e-27 92.8 4.1 9.9e-09 35.3 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EMD01068.1 - 1.2e-22 79.9 1.1 1.7e-09 38.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EMD01068.1 - 1.1e-20 73.9 0.8 1.3e-14 54.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EMD01068.1 - 2.7e-15 54.9 0.4 0.0074 16.7 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EMD01068.1 - 7e-12 45.2 4.0 0.007 16.8 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Sulfate_transp PF00916.20 EMD01070.1 - 2.5e-57 194.4 20.9 3.4e-57 193.9 20.9 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EMD01070.1 - 2.8e-14 53.0 0.0 5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EMD01070.1 - 5.9e-10 38.8 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EMD01070.1 - 0.083 13.2 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 STAS domain PH_6 PF15406.6 EMD01071.1 - 5.5e-26 91.1 0.1 1.2e-25 90.0 0.0 1.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EMD01071.1 - 5.4e-07 30.1 0.0 1.2e-06 28.9 0.0 1.6 2 0 0 2 2 2 1 PH domain UBD PF16455.5 EMD01073.1 - 4.3e-19 68.7 0.0 7.6e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 EMD01073.1 - 0.00078 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 EMD01073.1 - 0.00079 19.7 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EMD01073.1 - 0.0061 17.1 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 EMD01073.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EMD01073.1 - 0.17 12.0 0.0 0.47 10.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like S-methyl_trans PF02574.16 EMD01074.1 - 1.4e-73 248.0 0.0 1.6e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase AP_endonuc_2 PF01261.24 EMD01074.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Complex1_LYR PF05347.15 EMD01075.1 - 3.1e-09 36.8 0.7 6.9e-09 35.6 0.7 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) JAB PF01398.21 EMD01076.1 - 2.3e-09 37.2 0.0 6e-08 32.7 0.0 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GST_N_3 PF13417.6 EMD01077.1 - 4.8e-20 71.7 0.0 8.8e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EMD01077.1 - 1.7e-15 57.0 0.0 3.3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EMD01077.1 - 1.4e-10 41.3 0.0 3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EMD01077.1 - 1.3e-07 31.5 0.1 2.3e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EMD01077.1 - 1.6e-05 25.4 0.0 3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMD01077.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EMD01077.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EMD01077.1 - 0.059 13.6 0.0 0.43 10.8 0.1 2.2 2 0 0 2 2 2 0 Glutaredoxin HsdM_N PF12161.8 EMD01077.1 - 0.13 12.9 0.0 0.31 11.7 0.0 1.6 1 1 0 1 1 1 0 HsdM N-terminal domain zf-C2H2 PF00096.26 EMD01079.1 - 1.8e-06 28.1 8.7 3.2e-05 24.1 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EMD01079.1 - 4e-05 23.8 2.4 4e-05 23.8 2.4 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EMD01079.1 - 0.00069 19.5 0.2 0.0024 17.8 0.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EMD01079.1 - 0.011 16.5 0.8 0.011 16.5 0.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Myelin-PO_C PF10570.9 EMD01079.1 - 0.032 14.7 0.5 0.11 12.9 0.5 1.9 1 0 0 1 1 1 0 Myelin-PO cytoplasmic C-term p65 binding region zinc_ribbon_9 PF14369.6 EMD01079.1 - 0.15 12.3 0.7 0.44 10.8 0.7 1.8 1 1 0 1 1 1 0 zinc-ribbon IU_nuc_hydro PF01156.19 EMD01080.1 - 4.1e-52 177.6 0.1 2.4e-50 171.8 0.1 2.7 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Methyltransf_23 PF13489.6 EMD01081.1 - 1.6e-08 34.6 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EMD01081.1 - 7.6e-08 33.0 0.0 2.4e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMD01081.1 - 5e-07 29.6 0.0 2.5e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMD01081.1 - 2e-06 28.4 0.0 4.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMD01081.1 - 2.6e-06 28.1 0.0 8e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EMD01081.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EMD01081.1 - 0.2 11.2 0.0 0.5 9.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain MTCP1 PF08991.10 EMD01082.1 - 2.6e-29 101.2 12.2 3e-29 101.0 12.2 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EMD01082.1 - 0.26 11.5 12.0 0.11 12.6 9.4 1.7 2 0 0 2 2 2 0 CHCH domain Ligase_CoA PF00549.19 EMD01083.1 - 1.2e-33 116.1 4.2 8.4e-17 61.4 0.7 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EMD01083.1 - 3.1e-15 56.6 0.5 1.1e-14 54.8 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EMD01083.1 - 3.6e-10 39.8 1.5 3.8e-08 33.2 0.0 2.7 3 0 0 3 3 3 2 Succinyl-CoA ligase like flavodoxin domain DUF2478 PF10649.9 EMD01083.1 - 0.072 12.7 1.1 12 5.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2478) U1snRNP70_N PF12220.8 EMD01084.1 - 0.2 12.3 8.0 0.091 13.4 3.8 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_2 PF07724.14 EMD01086.1 - 7e-48 163.0 0.0 1.1e-46 159.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EMD01086.1 - 8.1e-36 122.1 2.5 8.1e-36 122.1 2.5 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EMD01086.1 - 8e-27 93.1 0.2 2.7e-26 91.4 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EMD01086.1 - 4.2e-20 72.5 0.1 7.2e-11 42.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EMD01086.1 - 2.7e-12 46.9 0.8 2.9e-08 33.8 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EMD01086.1 - 7.4e-09 36.2 9.1 0.00032 21.1 0.1 4.4 3 2 0 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 EMD01086.1 - 2.5e-07 30.5 0.6 7.9e-05 22.4 0.1 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 EMD01086.1 - 4e-07 30.4 3.5 0.025 14.9 0.1 4.3 4 2 0 4 4 2 2 AAA domain AAA_14 PF13173.6 EMD01086.1 - 1.1e-06 28.7 0.3 0.011 15.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 EMD01086.1 - 1.6e-06 27.7 0.1 0.0086 15.5 0.0 4.2 3 2 0 3 3 3 1 Bacterial TniB protein NACHT PF05729.12 EMD01086.1 - 1.1e-05 25.5 0.0 0.099 12.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 EMD01086.1 - 1.7e-05 24.4 0.1 0.056 13.0 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 EMD01086.1 - 6.9e-05 23.1 1.3 0.053 13.8 0.0 4.0 3 1 1 4 4 4 1 AAA domain IstB_IS21 PF01695.17 EMD01086.1 - 9.3e-05 22.2 0.0 0.49 10.1 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EMD01086.1 - 0.00011 21.7 0.1 0.87 8.9 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EMD01086.1 - 0.00012 22.0 7.5 0.45 10.4 0.1 4.0 3 2 2 5 5 4 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EMD01086.1 - 0.00038 20.3 0.0 0.31 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EMD01086.1 - 0.0004 20.9 0.9 1.5 9.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain SRP54 PF00448.22 EMD01086.1 - 0.0005 19.8 0.0 0.064 12.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ResIII PF04851.15 EMD01086.1 - 0.0014 18.7 0.0 4 7.4 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMD01086.1 - 0.0017 18.1 1.2 0.17 11.6 0.0 3.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 EMD01086.1 - 0.0018 18.6 0.1 0.93 9.9 0.0 2.9 2 1 0 2 2 2 1 RNA helicase DUF815 PF05673.13 EMD01086.1 - 0.0023 17.1 0.3 0.3 10.2 0.3 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EMD01086.1 - 0.0032 18.0 2.4 0.93 10.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter TrwB_AAD_bind PF10412.9 EMD01086.1 - 0.0045 16.0 0.1 0.81 8.5 0.1 3.0 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 EMD01086.1 - 0.005 16.8 0.1 4.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EMD01086.1 - 0.0062 16.8 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF853 PF05872.12 EMD01086.1 - 0.0063 15.2 0.1 0.02 13.5 0.0 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) RsgA_GTPase PF03193.16 EMD01086.1 - 0.01 15.7 0.0 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 EMD01086.1 - 0.014 15.0 0.0 1.3 8.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EMD01086.1 - 0.014 14.6 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 EMD01086.1 - 0.016 14.9 0.0 0.89 9.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EMD01086.1 - 0.024 14.8 0.0 11 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EMD01086.1 - 0.028 13.9 0.1 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.17 EMD01086.1 - 0.077 12.8 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EMD01086.1 - 0.085 12.6 0.1 8.4 6.2 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EMD01086.1 - 0.087 13.2 5.4 0.25 11.7 0.2 3.3 3 2 1 4 4 3 0 AAA domain NTPase_1 PF03266.15 EMD01086.1 - 0.1 12.5 0.6 1.5 8.7 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA_21 PF13304.6 EMD01086.1 - 0.14 11.9 3.7 0.37 10.6 0.0 3.0 3 1 1 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system UvrD-helicase PF00580.21 EMD01086.1 - 0.22 11.0 3.0 0.74 9.3 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF4094 PF13334.6 EMD01086.1 - 1.1 9.7 4.5 0.72 10.3 0.6 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) Seryl_tRNA_N PF02403.22 EMD01086.1 - 2 8.7 14.9 2.8 8.2 12.6 2.5 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 EMD01086.1 - 3 7.1 8.3 5.1 6.4 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EMD01086.1 - 3.6 6.6 9.6 6 5.8 9.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 EMD01086.1 - 5.7 7.0 12.4 12 6.0 12.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EF1_GNE PF00736.19 EMD01087.1 - 1.4e-33 114.9 1.3 2.5e-33 114.1 1.3 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EMD01087.1 - 3.4e-07 30.6 11.4 7.8e-07 29.4 11.4 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 EMD01087.1 - 0.0031 17.7 0.5 0.011 15.9 0.1 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EMD01087.1 - 0.015 15.5 0.1 0.056 13.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Usher_TcfC PF17271.2 EMD01087.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 TcfC Usher-like barrel domain bZIP_2 PF07716.15 EMD01089.1 - 4e-07 30.0 11.1 4e-07 30.0 11.1 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EMD01089.1 - 2.4e-06 27.6 6.5 2.4e-06 27.6 6.5 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 EMD01089.1 - 0.0007 20.1 6.9 0.0012 19.3 6.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Lebercilin PF15619.6 EMD01089.1 - 0.0014 18.3 3.0 0.0019 17.9 3.0 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF4472 PF14739.6 EMD01089.1 - 0.027 15.2 2.4 0.04 14.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) M PF02370.16 EMD01089.1 - 0.056 14.0 0.8 2.3 9.1 0.2 2.5 1 1 1 2 2 2 0 M protein repeat ABC_tran_CTD PF16326.5 EMD01089.1 - 0.061 13.6 1.8 0.12 12.6 1.8 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain HALZ PF02183.18 EMD01089.1 - 0.35 11.1 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ax_dynein_light PF10211.9 EMD01089.1 - 0.37 10.7 3.9 0.53 10.2 3.9 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain MFS_1 PF07690.16 EMD01090.1 - 2.2e-41 141.9 46.9 4.3e-41 141.0 37.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMD01090.1 - 4.7e-14 52.1 10.1 4.7e-14 52.1 10.1 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.18 EMD01091.1 - 1.3e-15 57.2 0.0 2.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD01091.1 - 1.7e-08 34.5 9.2 2.7e-08 33.8 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEC-1_N PF04625.13 EMD01091.1 - 0.37 9.8 10.0 0.62 9.0 10.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Mito_fiss_reg PF05308.11 EMD01091.1 - 0.58 10.2 4.6 1.4 9.0 4.6 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator CTP_transf_1 PF01148.20 EMD01092.1 - 0.035 13.9 4.9 0.093 12.5 1.3 2.3 2 0 0 2 2 2 0 Cytidylyltransferase family Ribosomal_L6e PF01159.19 EMD01093.1 - 3.5e-38 130.5 0.0 4.2e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.13 EMD01094.1 - 2.8e-27 95.1 0.0 4.2e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EMD01094.1 - 1.5e-08 34.8 0.1 1.9e-07 31.2 0.1 2.2 1 1 0 1 1 1 1 UCH-binding domain MutS_V PF00488.21 EMD01095.1 - 1.1e-49 169.0 0.1 2.1e-49 168.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EMD01095.1 - 3.2e-22 79.7 0.3 6.4e-22 78.7 0.3 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EMD01095.1 - 0.035 14.5 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV MMgT PF10270.9 EMD01096.1 - 1.4e-31 108.8 0.0 1.8e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter TMEM100 PF16311.5 EMD01096.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 CD20 PF04103.15 EMD01096.1 - 0.73 9.9 4.0 4.7 7.3 0.7 2.1 2 0 0 2 2 2 0 CD20-like family Lipoxygenase PF00305.19 EMD01099.1 - 7.9e-31 107.2 0.6 1.6e-30 106.2 0.6 1.4 1 1 0 1 1 1 1 Lipoxygenase CK_II_beta PF01214.18 EMD01100.1 - 3.6e-78 261.6 0.0 8.5e-78 260.3 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit DUF4637 PF15470.6 EMD01100.1 - 0.006 16.3 4.7 0.006 16.3 4.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4637) Spt5_N PF11942.8 EMD01100.1 - 0.077 14.0 22.9 1.5 9.9 11.5 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal BSP_II PF05432.11 EMD01100.1 - 0.15 11.7 11.1 0.9 9.2 3.5 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 EMD01100.1 - 1.4 8.7 5.3 17 5.2 0.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region CDC45 PF02724.14 EMD01100.1 - 1.7 6.8 13.8 0.76 8.0 5.6 2.1 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 EMD01100.1 - 3.5 5.7 11.4 0.13 10.5 2.4 2.0 2 0 0 2 2 2 0 Nop14-like family FAM176 PF14851.6 EMD01100.1 - 3.9 7.1 11.4 2.9 7.5 4.4 2.2 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 EMD01100.1 - 6 6.9 8.4 0.93 9.5 2.1 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal SDA1 PF05285.12 EMD01100.1 - 7.6 5.9 13.1 2.3 7.6 5.0 2.1 2 0 0 2 2 2 0 SDA1 WRNPLPNID PF15017.6 EMD01100.1 - 7.8 7.5 16.4 4.9 8.1 7.5 2.4 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RRM_1 PF00076.22 EMD01102.1 - 4e-59 196.3 0.0 1.5e-18 66.3 0.0 5.7 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EMD01102.1 - 7e-06 26.4 0.7 11 6.2 0.0 6.0 4 2 2 6 6 6 1 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 EMD01102.1 - 0.0045 16.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain NosL PF05573.12 EMD01102.1 - 0.01 16.2 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 NosL RRM_7 PF16367.5 EMD01102.1 - 0.022 14.9 0.0 24 5.1 0.0 3.6 3 0 0 3 3 3 0 RNA recognition motif CDC45 PF02724.14 EMD01102.1 - 1.5 7.0 7.8 3.6 5.8 7.8 1.6 1 0 0 1 1 1 0 CDC45-like protein Cathelicidins PF00666.17 EMD01103.1 - 0.025 14.9 1.3 0.028 14.7 1.3 1.1 1 0 0 1 1 1 0 Cathelicidin Cyt-b5 PF00173.28 EMD01104.1 - 6.7e-11 42.2 0.1 7.7e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UQ_con PF00179.26 EMD01106.1 - 1.8e-15 56.8 0.0 3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nop14 PF04147.12 EMD01106.1 - 1.2 7.3 14.4 1.6 6.8 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EMD01106.1 - 8.4 5.6 19.0 12 5.1 19.0 1.1 1 0 0 1 1 1 0 BUD22 Dor1 PF04124.12 EMD01107.1 - 1.2e-49 168.8 8.2 2.3e-35 121.9 8.5 2.1 2 0 0 2 2 2 2 Dor1-like family GAS PF13851.6 EMD01107.1 - 0.0026 17.2 0.5 0.0051 16.2 0.5 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Vps51 PF08700.11 EMD01107.1 - 0.059 13.4 0.6 0.18 11.9 0.6 1.8 1 0 0 1 1 1 0 Vps51/Vps67 LRR_9 PF14580.6 EMD01107.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat Syntaxin-6_N PF09177.11 EMD01107.1 - 1.2 9.7 4.0 4 8.1 0.7 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal AKNA PF12443.8 EMD01107.1 - 4.1 8.1 6.7 2.1 9.0 0.2 3.2 3 0 0 3 3 3 0 AT-hook-containing transcription factor zf-C2H2 PF00096.26 EMD01109.1 - 1.2e-11 44.3 12.0 0.00023 21.4 0.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EMD01109.1 - 6.6e-09 35.9 8.4 0.0063 17.2 0.3 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 EMD01109.1 - 0.0038 17.5 6.3 0.007 16.6 0.4 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EMD01109.1 - 0.054 13.9 11.4 0.79 10.3 0.5 4.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_12 PF18658.1 EMD01109.1 - 0.069 12.7 0.2 0.2 11.3 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-C2H2_11 PF16622.5 EMD01109.1 - 0.077 12.8 4.7 3.6 7.4 0.2 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type CHORD PF04968.12 EMD01109.1 - 0.17 12.6 1.3 0.47 11.2 1.3 1.8 1 0 0 1 1 1 0 CHORD PSP1 PF04468.12 EMD01111.1 - 1.1e-25 89.7 1.1 1.8e-25 89.0 1.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF4149 PF13664.6 EMD01112.1 - 7.3e-25 87.3 0.6 7.3e-25 87.3 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Glyco_hydro_3_C PF01915.22 EMD01113.1 - 8.5e-45 153.2 0.0 1.6e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EMD01113.1 - 3.9e-35 121.7 0.0 6.1e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EMD01113.1 - 1.3e-12 47.6 0.0 2.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain 2OG-FeII_Oxy_2 PF13532.6 EMD01114.1 - 1.8e-12 47.9 0.0 8.4e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EMD01114.1 - 0.0025 18.3 0.1 0.006 17.1 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Dynactin_p62 PF05502.13 EMD01115.1 - 1.1e-141 472.9 18.3 1.5e-90 304.3 0.0 2.1 1 1 1 2 2 2 2 Dynactin p62 family Cadherin_2 PF08266.12 EMD01117.1 - 0.015 15.1 1.3 1.5 8.7 0.0 3.1 1 1 2 3 3 3 0 Cadherin-like Sld5 PF05916.11 EMD01117.1 - 0.048 14.1 0.1 5 7.6 0.0 2.3 1 1 1 2 2 2 0 GINS complex protein TAF PF02969.17 EMD01117.1 - 0.53 10.5 2.4 1e+02 3.2 0.0 4.1 3 2 0 4 4 4 0 TATA box binding protein associated factor (TAF) Glyco_trans_2_3 PF13632.6 EMD01119.1 - 4.1e-20 72.5 0.5 4.1e-20 72.5 0.5 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EMD01119.1 - 1.6e-17 64.2 0.0 9.7e-17 61.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EMD01119.1 - 1.2e-15 57.7 0.0 1.7e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EMD01119.1 - 1.4e-13 50.7 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 EMD01119.1 - 1.4e-05 23.8 0.7 0.0014 17.3 0.0 2.4 2 1 0 2 2 2 2 Cellulose synthase Marek_SORF3 PF07153.11 EMD01119.1 - 0.083 12.2 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Marek's disease-like virus SORF3 protein Chitin_synth_2 PF03142.15 EMD01119.1 - 0.11 11.1 0.1 3.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Chitin synthase EamA PF00892.20 EMD01120.1 - 1.3e-09 38.4 19.5 7e-05 23.0 6.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EMD01120.1 - 2e-09 37.1 1.9 3.1e-09 36.5 1.9 1.3 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EMD01120.1 - 6.8e-09 35.3 0.1 1e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 EMD01120.1 - 4.4e-06 26.2 0.6 4.4e-06 26.2 0.6 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family PUNUT PF16913.5 EMD01120.1 - 0.029 13.6 0.4 0.029 13.6 0.4 2.1 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport DUF2760 PF10816.8 EMD01120.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) F-box PF00646.33 EMD01121.1 - 0.2 11.6 6.6 0.25 11.3 0.7 2.8 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EMD01121.1 - 0.34 10.9 7.4 1.3 9.0 5.2 2.6 1 1 1 2 2 2 0 F-box-like Glyoxalase_3 PF13468.6 EMD01122.1 - 9.8e-25 87.7 0.0 1.3e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain IBR PF01485.21 EMD01123.1 - 1.1e-12 48.0 37.9 4.6e-07 30.0 3.2 3.4 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain CENP-B_dimeris PF09026.10 EMD01123.1 - 0.32 11.4 3.9 0.65 10.4 3.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Fungal_trans PF04082.18 EMD01125.1 - 9.2e-27 93.7 0.0 1.7e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD01125.1 - 2.8e-11 43.4 12.6 4.7e-11 42.6 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3402 PF11882.8 EMD01125.1 - 0.18 10.9 0.7 0.34 10.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) SET PF00856.28 EMD01126.1 - 7.4e-10 39.5 0.4 9.3e-09 35.9 0.0 2.2 1 1 1 2 2 2 1 SET domain DUF4451 PF14616.6 EMD01128.1 - 0.00051 20.2 3.1 0.01 16.1 0.4 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4451) p450 PF00067.22 EMD01129.1 - 4.4e-66 223.5 0.0 6.7e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Med31 PF05669.12 EMD01130.1 - 4.6e-36 122.7 1.9 5.4e-36 122.5 1.9 1.0 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 EMD01131.1 - 4.1e-42 144.2 0.7 4.1e-42 144.2 0.7 3.5 3 1 0 3 3 3 1 Pal1 cell morphology protein U1snRNP70_N PF12220.8 EMD01131.1 - 0.84 10.3 8.4 2.8 8.6 8.4 1.9 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CDC45 PF02724.14 EMD01131.1 - 1 7.6 4.9 1.5 7.0 4.9 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIS_C PF01096.18 EMD01132.1 - 5.1e-18 64.6 10.1 2.8e-17 62.3 2.8 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EMD01132.1 - 2.9e-07 30.2 10.8 0.0019 18.0 0.1 3.5 4 0 0 4 4 4 2 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.8 EMD01132.1 - 0.023 14.4 0.1 0.023 14.4 0.1 1.7 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DUF4720 PF15846.5 EMD01132.1 - 0.11 12.4 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4720) DUF951 PF06107.11 EMD01132.1 - 0.22 11.5 0.2 0.22 11.5 0.2 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF951) Zn_Tnp_IS1595 PF12760.7 EMD01132.1 - 0.23 11.5 8.6 0.38 10.8 1.7 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-Mss51 PF13824.6 EMD01132.1 - 0.96 9.6 5.6 1.4 9.0 0.5 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-tcix PF14952.6 EMD01132.1 - 1.3 8.7 0.1 1.3 8.7 0.1 3.2 4 0 0 4 4 4 0 Putative treble-clef, zinc-finger, Zn-binding Ank_4 PF13637.6 EMD01133.1 - 1.8e-09 37.9 0.0 1.3e-07 32.0 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EMD01133.1 - 6e-09 35.4 0.0 0.0041 17.5 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EMD01133.1 - 1.7e-08 34.9 0.0 3.6e-07 30.7 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EMD01133.1 - 7.3e-06 26.2 0.0 0.0078 16.5 0.0 3.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EMD01133.1 - 1e-05 25.7 0.0 0.74 10.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat VWA_2 PF13519.6 EMD01133.1 - 0.02 15.6 0.0 0.31 11.7 0.0 2.3 2 1 0 3 3 3 0 von Willebrand factor type A domain LPD18 PF18832.1 EMD01135.1 - 0.12 12.5 1.3 1 9.4 0.1 2.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 18 Arrestin_C PF02752.22 EMD01136.1 - 8.2e-09 36.0 0.0 2.6e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain bZIP_1 PF00170.21 EMD01137.1 - 6.2e-06 26.2 7.2 1.1e-05 25.5 7.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EMD01137.1 - 0.0072 16.4 7.4 0.017 15.2 7.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper ABC_tran_Xtn PF12848.7 EMD01137.1 - 0.49 10.5 6.8 1.7 8.7 6.8 1.9 1 0 0 1 1 1 0 ABC transporter DUF4407 PF14362.6 EMD01137.1 - 1.5 8.1 8.2 0.32 10.3 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Stm1_N PF09598.10 EMD01138.1 - 2.6e-17 63.4 1.8 2.6e-17 63.4 1.8 3.9 4 1 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 EMD01138.1 - 9.5e-10 39.3 1.1 9.5e-10 39.3 1.1 3.0 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family DUF3602 PF12223.8 EMD01139.1 - 1.7e-09 38.1 14.8 8e-06 26.4 5.0 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Kri1 PF05178.12 EMD01140.1 - 4.4e-29 101.1 15.8 4.4e-29 101.1 15.8 5.2 6 1 0 6 6 6 1 KRI1-like family Kri1_C PF12936.7 EMD01140.1 - 1.4e-28 98.8 0.3 1.4e-28 98.8 0.3 4.0 4 1 1 5 5 5 1 KRI1-like family C-terminal DUF836 PF05768.14 EMD01141.1 - 1.5e-14 54.1 0.0 1.9e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EMD01141.1 - 4.3e-05 23.7 0.2 8.3e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Glutaredoxin HpcH_HpaI PF03328.14 EMD01142.1 - 3e-32 111.6 0.0 4.1e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MRJP PF03022.16 EMD01143.1 - 4.5e-20 72.2 0.1 6.4e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 Major royal jelly protein LPMO_10 PF03067.15 EMD01144.1 - 0.0005 20.8 0.0 0.00062 20.5 0.0 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 EMD01144.1 - 0.017 15.0 0.1 0.04 13.8 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 DEAD PF00270.29 EMD01145.1 - 1.4e-32 112.9 0.0 1.1e-31 110.0 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EMD01145.1 - 2.6e-19 69.6 0.0 5.2e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EMD01145.1 - 1.1e-16 60.7 0.0 3.2e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EMD01145.1 - 3.5e-06 27.1 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EMD01145.1 - 0.053 13.8 0.1 0.77 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain INCENP_ARK-bind PF03941.15 EMD01146.1 - 1.2e-16 60.3 0.1 5.5e-16 58.3 0.1 2.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region GRASP55_65 PF04495.14 EMD01147.1 - 1.2e-46 158.4 0.0 8.2e-44 149.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EMD01147.1 - 0.004 17.0 0.0 0.73 9.7 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EMD01147.1 - 0.009 16.3 0.0 9.3 6.7 0.0 2.9 3 0 0 3 3 3 2 PDZ domain XFP_N PF09364.10 EMD01148.1 - 1.7e-170 566.7 0.0 2.6e-170 566.1 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 EMD01148.1 - 8.8e-84 279.6 0.0 1.7e-83 278.6 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 EMD01148.1 - 1.1e-79 266.6 0.0 1.8e-79 265.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.21 EMD01148.1 - 0.073 12.9 0.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Isochorismatase PF00857.20 EMD01149.1 - 8.7e-33 114.0 0.0 1.1e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Glycophorin_A PF01102.18 EMD01150.1 - 1.1 9.5 7.8 12 6.1 7.8 2.3 1 1 0 1 1 1 0 Glycophorin A Sulfotransfer_4 PF17784.1 EMD01152.1 - 8.1e-26 91.2 1.8 1.2e-22 80.9 1.8 2.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EMD01152.1 - 1.9e-05 25.2 2.1 0.021 15.2 0.3 2.2 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EMD01152.1 - 0.07 12.6 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase domain MpPF1 PF07668.11 EMD01155.1 - 0.0064 15.8 0.9 0.0064 15.8 0.9 1.6 1 1 0 1 1 1 1 M penetrans paralogue family 1 TRAF_BIRC3_bd PF16673.5 EMD01155.1 - 0.1 12.4 12.2 0.38 10.6 1.3 3.4 1 1 2 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain ChaB PF06150.12 EMD01155.1 - 3.5 8.3 8.3 1.3 9.7 0.7 3.3 3 0 0 3 3 3 0 ChaB DUF3135 PF11333.8 EMD01155.1 - 9.7 6.5 11.9 5.8 7.2 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3135) NUDIX PF00293.28 EMD01156.1 - 1.8e-05 24.8 0.1 3.3e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 NUDIX domain PhoLip_ATPase_C PF16212.5 EMD01157.1 - 9.5e-71 238.4 8.1 9.5e-71 238.4 8.1 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EMD01157.1 - 6.7e-19 67.3 0.0 1.9e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EMD01157.1 - 5.4e-11 43.2 0.3 1.7e-05 25.2 0.0 3.7 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EMD01157.1 - 2.4e-10 40.4 0.0 3.2e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EMD01157.1 - 4e-09 36.2 0.0 9.7e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EMD01157.1 - 0.0018 18.1 0.0 0.009 15.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATG16 PF08614.11 EMD01158.1 - 0.0012 19.2 79.9 0.093 12.9 11.6 4.2 1 1 3 4 4 4 4 Autophagy protein 16 (ATG16) Filament PF00038.21 EMD01158.1 - 0.0013 18.3 11.1 0.0013 18.3 11.1 3.5 1 1 2 3 3 3 2 Intermediate filament protein TMF_DNA_bd PF12329.8 EMD01158.1 - 0.005 16.8 4.1 0.005 16.8 4.1 7.5 1 1 6 9 9 9 2 TATA element modulatory factor 1 DNA binding DUF4577 PF15145.6 EMD01158.1 - 0.19 11.7 7.7 5.4 7.1 0.5 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4577) MscS_porin PF12795.7 EMD01158.1 - 0.2 11.1 59.3 0.34 10.4 25.5 3.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 EMD01158.1 - 0.39 10.8 73.7 0.16 12.0 23.2 4.9 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein YqzH PF14164.6 EMD01158.1 - 1.4 9.0 3.5 20 5.3 0.2 3.4 3 0 0 3 3 3 0 YqzH-like protein PHD PF00628.29 EMD01160.1 - 1.9e-11 43.6 5.8 4.9e-11 42.4 5.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 EMD01160.1 - 0.0079 16.0 1.5 0.67 9.7 0.1 2.4 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain zf-RING_2 PF13639.6 EMD01160.1 - 2.8 8.3 6.0 6.6 7.2 6.0 1.6 1 0 0 1 1 1 0 Ring finger domain Steroid_dh PF02544.16 EMD01161.1 - 3.2e-10 40.2 1.2 3.5e-10 40.0 0.1 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EMD01161.1 - 0.013 15.0 0.6 0.013 15.0 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) DUF3961 PF13106.6 EMD01161.1 - 8.3 6.1 6.2 2.7 7.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) NmrA PF05368.13 EMD01162.1 - 1.1e-10 41.5 0.0 1.9e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EMD01162.1 - 7.9e-09 35.7 0.0 9.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EMD01162.1 - 0.0014 18.1 0.0 0.0062 16.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EMD01162.1 - 0.0021 17.3 0.0 0.0078 15.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EMD01162.1 - 0.0033 16.9 0.0 0.0075 15.7 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Ferric_reduct PF01794.19 EMD01164.1 - 5.6e-20 71.7 9.7 5.6e-20 71.7 9.7 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EMD01164.1 - 2e-16 60.5 0.0 3.6e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EMD01164.1 - 2.5e-09 37.2 0.0 5.3e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EMD01164.1 - 0.069 13.8 0.0 6.1 7.5 0.0 2.7 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Stb3 PF10330.9 EMD01166.1 - 1.3e-31 108.4 0.0 2.5e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Uso1_p115_head PF04869.14 EMD01169.1 - 7.3e-61 206.0 0.0 1.3e-60 205.1 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EMD01169.1 - 2.5e-14 53.7 25.9 2.5e-14 53.7 25.9 5.0 3 1 2 5 5 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 EMD01169.1 - 0.0049 17.1 14.4 0.0049 17.1 14.4 5.2 2 2 2 4 4 4 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EMD01169.1 - 7.6 5.3 51.2 0.3 9.9 22.4 3.4 1 1 3 4 4 4 0 Spc7 kinetochore protein Mt_ATP-synt_B PF05405.14 EMD01169.1 - 7.6 6.1 17.1 0.37 10.4 8.9 2.6 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Amino_oxidase PF01593.24 EMD01170.1 - 6.4e-64 216.9 1.6 5.4e-63 213.9 1.6 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EMD01170.1 - 1.6e-15 57.1 0.2 3.3e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EMD01170.1 - 7.6e-05 22.4 3.3 0.0018 18.0 3.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EMD01170.1 - 0.00094 18.5 0.8 0.29 10.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EMD01170.1 - 0.0041 17.1 1.0 0.023 14.7 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EMD01170.1 - 0.0078 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EMD01170.1 - 0.01 14.5 0.1 0.45 9.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 EMD01170.1 - 0.048 12.9 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EMD01171.1 - 5.2e-44 150.6 52.9 1.4e-42 145.9 53.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Tam41_Mmp37 PF09139.11 EMD01173.1 - 4.4e-127 424.0 0.0 5.2e-127 423.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial BIR PF00653.21 EMD01174.1 - 4.5e-44 149.0 4.5 3.8e-22 78.7 0.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Tim54 PF11711.8 EMD01175.1 - 4e-141 470.1 0.1 4.6e-141 470.0 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 ADH_N PF08240.12 EMD01176.1 - 1.8e-24 85.7 0.6 3.9e-24 84.6 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMD01176.1 - 2.9e-20 72.6 0.9 5.8e-20 71.6 0.6 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EMD01176.1 - 0.0056 16.0 0.4 0.0094 15.3 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 EMD01178.1 - 2e-12 46.7 0.1 3.4e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD01178.1 - 2.5e-07 30.7 9.6 5e-07 29.7 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EMD01179.1 - 1.5e-06 28.3 9.0 1.5e-06 28.3 9.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EMD01179.1 - 6e-06 25.3 0.4 1.6e-05 23.9 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Yos1 PF08571.10 EMD01179.1 - 0.35 11.2 1.2 0.53 10.6 0.2 1.8 2 0 0 2 2 2 0 Yos1-like Methyltransf_4 PF02390.17 EMD01180.1 - 3.3e-52 176.4 0.0 4e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EMD01180.1 - 0.00015 22.4 0.1 0.00036 21.2 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EMD01180.1 - 0.00015 22.4 0.0 0.00033 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EMD01180.1 - 0.002 18.0 0.0 0.0024 17.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EMD01180.1 - 0.0026 17.3 0.0 0.0057 16.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EMD01180.1 - 0.0043 17.1 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EMD01180.1 - 0.087 13.5 0.0 0.25 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Hira PF07569.11 EMD01181.1 - 1.9e-81 273.0 0.0 3.2e-81 272.3 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EMD01181.1 - 2.1e-28 98.0 17.7 1.6e-05 25.5 0.0 8.4 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMD01181.1 - 1.6e-12 47.6 0.0 0.077 13.3 0.0 6.1 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EMD01181.1 - 5.3e-08 32.5 0.1 1.1e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 EMD01181.1 - 0.00013 21.1 0.3 0.36 9.7 0.0 4.7 5 1 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EMD01181.1 - 0.011 13.8 0.4 0.16 9.9 0.0 2.5 3 0 0 3 3 3 0 IKI3 family PD40 PF07676.12 EMD01181.1 - 0.012 15.6 0.1 12 5.9 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CAP_GLY PF01302.25 EMD01182.1 - 3.9e-17 62.0 0.1 7e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EMD01182.1 - 2.6e-06 27.7 7.3 0.03 14.8 0.0 4.5 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EMD01182.1 - 7.9e-06 25.5 4.1 0.25 11.1 0.0 4.1 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EMD01182.1 - 0.0015 18.4 1.3 1.6 9.0 0.1 4.0 3 0 0 3 3 3 1 Leucine Rich repeat RepA1_leader PF08048.12 EMD01182.1 - 0.1 12.9 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Tap RepA1 leader peptide CBFD_NFYB_HMF PF00808.23 EMD01184.1 - 1.2e-09 38.3 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EMD01184.1 - 0.00073 19.6 0.1 0.0011 19.1 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EMD01184.1 - 0.0071 16.7 0.1 0.02 15.2 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF3530 PF12048.8 EMD01184.1 - 0.011 15.2 0.1 0.011 15.2 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3530) Afi1 PF07792.12 EMD01184.1 - 1.9 9.0 11.0 0.37 11.3 0.1 2.7 1 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CRC_subunit PF08624.10 EMD01185.1 - 9e-51 171.9 0.5 1.2e-50 171.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.19 EMD01186.1 - 4.7e-98 328.5 0.2 6.7e-98 328.0 0.2 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EMD01186.1 - 1.7e-30 104.8 0.3 4.1e-30 103.6 0.3 1.7 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 EMD01186.1 - 2.5e-28 98.6 0.0 5e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 EMD01186.1 - 3.4e-20 71.9 0.0 1.5e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EMD01186.1 - 7.8e-10 38.8 0.6 7e-06 26.1 0.0 3.1 4 0 0 4 4 4 2 Cold shock domain PIN_4 PF13638.6 EMD01186.1 - 6.1e-09 36.2 5.8 1e-08 35.5 0.1 3.7 3 1 1 4 4 4 1 PIN domain Dis3l2_C_term PF17877.1 EMD01186.1 - 0.071 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Zn_clus PF00172.18 EMD01187.1 - 0.018 15.2 5.1 0.018 15.2 5.1 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pullulanase_N2 PF17967.1 EMD01187.1 - 0.17 12.8 1.5 0.28 12.1 0.1 2.2 3 0 0 3 3 3 0 Pullulanase N2 domain Fungal_trans PF04082.18 EMD01188.1 - 3.5e-05 23.0 0.0 6.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD01188.1 - 2 8.6 10.5 3.8 7.7 10.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_11 PF08279.12 EMD01189.1 - 0.021 14.8 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 HTH domain FMO-like PF00743.19 EMD01190.1 - 4.4e-15 55.1 0.0 2.2e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EMD01190.1 - 2.4e-11 43.4 0.0 1.5e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMD01190.1 - 2.6e-10 40.4 0.0 8.7e-10 38.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EMD01190.1 - 1e-08 34.8 0.0 8.6e-06 25.2 0.0 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EMD01190.1 - 2.9e-06 27.1 0.1 0.00064 19.4 0.1 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EMD01190.1 - 2.5e-05 23.6 0.0 0.0033 16.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EMD01190.1 - 0.0001 22.3 0.4 0.0033 17.4 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EMD01190.1 - 0.0023 18.4 0.0 0.19 12.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EMD01190.1 - 0.018 14.4 0.0 1 8.6 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 EMD01190.1 - 0.14 12.2 0.0 27 4.8 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EMD01190.1 - 0.16 11.2 0.0 13 5.0 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Abhydrolase_6 PF12697.7 EMD01191.1 - 6e-11 43.4 3.1 1.8e-10 41.8 3.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EMD01191.1 - 1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EMD01191.1 - 0.071 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Chlorophyllase2 PF12740.7 EMD01191.1 - 0.12 11.3 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Tocopherol_cycl PF14249.6 EMD01192.1 - 0.00052 19.2 0.4 0.0018 17.5 0.1 2.0 2 1 0 2 2 2 1 Tocopherol cyclase TT_ORF2 PF02957.15 EMD01193.1 - 0.043 14.7 1.4 0.043 14.7 1.4 3.7 1 1 2 4 4 4 0 TT viral ORF2 RNase_PH PF01138.21 EMD01195.1 - 3.8e-13 50.1 0.1 5.8e-12 46.3 0.1 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EMD01195.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Voltage_CLC PF00654.20 EMD01197.1 - 2.8e-87 293.3 19.0 2.8e-87 293.3 19.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EMD01197.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 CBS domain Choline_kinase PF01633.20 EMD01199.1 - 2.2e-50 171.2 0.0 7.4e-49 166.2 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EMD01199.1 - 7.6e-10 39.1 0.0 1.4e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EMD01199.1 - 0.057 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase UQ_con PF00179.26 EMD01200.1 - 5.2e-32 110.4 0.0 8.2e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Alpha-mann_mid PF09261.11 EMD01200.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha mannosidase middle domain Prok-E2_B PF14461.6 EMD01200.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B PI-PLC-X PF00388.19 EMD01201.1 - 5e-11 42.4 0.0 8.6e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Pkinase PF00069.25 EMD01202.1 - 1.5e-58 198.3 0.0 4.7e-57 193.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD01202.1 - 4.9e-25 88.3 0.2 4.8e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EMD01202.1 - 6.6e-06 25.3 0.3 1.8e-05 23.9 0.1 1.6 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 EMD01202.1 - 2e-05 24.6 0.1 0.037 13.9 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EMD01202.1 - 0.00062 19.2 0.0 0.0033 16.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EMD01202.1 - 0.0089 15.4 0.5 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FAD-SLDH PF12318.8 EMD01202.1 - 0.039 14.0 0.1 0.1 12.6 0.0 1.7 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase RIO1 PF01163.22 EMD01202.1 - 0.042 13.4 1.6 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 EMD01202.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3584 PF12128.8 EMD01203.1 - 5e-06 24.4 31.1 5e-06 24.4 31.1 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3584) Filament PF00038.21 EMD01203.1 - 6.9 6.2 69.1 0.011 15.3 12.0 5.1 4 1 1 5 5 5 0 Intermediate filament protein Aldo_ket_red PF00248.21 EMD01204.1 - 8e-51 173.0 0.0 1.5e-50 172.1 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 EMD01205.1 - 5.1e-25 88.1 47.8 1.3e-13 50.6 24.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EMD01205.1 - 0.00037 19.2 18.3 0.00037 19.2 18.3 2.6 1 1 2 3 3 3 2 MFS/sugar transport protein Fe_hyd_lg_C PF02906.14 EMD01206.1 - 6.8e-53 179.8 0.0 1.7e-52 178.5 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Ribosomal_L10 PF00466.20 EMD01207.1 - 0.013 15.6 0.1 0.037 14.2 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L10 Glycos_transf_3 PF00591.21 EMD01208.1 - 1.4e-55 188.6 0.0 2.7e-55 187.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EMD01208.1 - 4.2e-08 32.9 0.1 9.3e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain RunxI PF08504.11 EMD01208.1 - 0.82 10.4 3.3 6.2 7.6 0.0 2.8 2 1 1 3 3 3 0 Runx inhibition domain Acetyltransf_10 PF13673.7 EMD01209.1 - 4e-07 30.0 0.0 4.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMD01209.1 - 4.8e-07 30.1 0.0 5.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EMD01209.1 - 3.8e-06 27.1 0.0 4.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EMD01209.1 - 0.0002 21.3 0.0 0.00033 20.6 0.0 1.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EMD01209.1 - 0.00029 20.9 0.0 0.00037 20.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EMD01209.1 - 0.18 11.4 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 MOZ/SAS family FAD_binding_3 PF01494.19 EMD01211.1 - 1.3e-09 37.7 0.1 3.9e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EMD01211.1 - 0.011 15.0 0.2 0.84 8.8 0.0 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EMD01211.1 - 0.049 13.9 0.1 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SUIM_assoc PF16619.5 EMD01212.1 - 0.9 9.7 9.1 1.8 8.7 2.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Mito_fiss_reg PF05308.11 EMD01213.1 - 0.49 10.4 6.0 0.54 10.3 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EMD01213.1 - 0.57 9.6 5.1 0.63 9.5 5.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ESSS PF10183.9 EMD01214.1 - 1.8e-16 60.2 0.0 2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2293 PF10056.9 EMD01215.1 - 1.7e-19 69.8 0.0 6.1e-19 68.1 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) SNF5 PF04855.12 EMD01216.1 - 6.7e-77 258.5 0.0 9.1e-77 258.0 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EMD01216.1 - 0.00037 20.0 4.4 0.0011 18.5 4.4 1.9 1 1 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 EMD01216.1 - 0.22 11.3 5.6 0.42 10.4 1.8 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain WD40 PF00400.32 EMD01217.1 - 3.9e-43 144.6 16.1 2.5e-08 34.4 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EMD01217.1 - 5e-06 26.7 0.6 4.9 7.5 0.0 5.1 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EMD01217.1 - 0.014 14.1 3.5 4.3 5.9 0.2 3.6 1 1 3 4 4 4 0 Nucleoporin Nup120/160 COA2 PF17051.5 EMD01218.1 - 3e-05 24.0 0.1 4.3e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 UreE_N PF02814.15 EMD01218.1 - 0.031 13.8 0.3 1.5 8.5 0.3 2.3 1 1 1 2 2 2 0 UreE urease accessory protein, N-terminal domain YdaS_antitoxin PF15943.5 EMD01219.1 - 0.0053 16.6 0.1 0.0085 15.9 0.1 1.4 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT GLE1 PF07817.13 EMD01221.1 - 2.8e-28 98.8 0.0 9.5e-14 51.2 0.1 2.3 1 1 1 2 2 2 2 GLE1-like protein DUF572 PF04502.13 EMD01221.1 - 6.2 6.3 26.2 9 5.8 26.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2278 PF10042.9 EMD01222.1 - 3.3e-63 213.4 0.0 3.3e-63 213.4 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2278) RNB PF00773.19 EMD01223.1 - 4.2e-87 292.5 0.0 1.1e-86 291.2 0.0 1.7 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EMD01223.1 - 6e-27 93.5 0.0 2e-26 91.8 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EMD01223.1 - 2.1e-26 92.0 0.0 7.1e-26 90.4 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EMD01223.1 - 9.7e-06 25.7 0.0 0.0055 16.8 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EMD01223.1 - 0.00084 19.1 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain DUF4778 PF16008.5 EMD01223.1 - 1.5 8.8 7.4 0.21 11.6 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) FA_hydroxylase PF04116.13 EMD01225.1 - 9e-13 48.7 4.0 9e-13 48.7 4.0 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3425 PF11905.8 EMD01226.1 - 1.5e-12 47.6 0.0 3.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_1 PF00561.20 EMD01226.1 - 5.9e-07 29.4 0.0 2.6e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EMD01226.1 - 0.001 19.7 11.4 0.001 19.7 11.4 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family DNA_pol_phi PF04931.13 EMD01226.1 - 0.82 7.7 4.4 1.3 7.1 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 EMD01226.1 - 1 9.0 5.3 6.4 6.4 5.3 2.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EMD01226.1 - 2.8 7.2 8.9 5.5 6.2 8.9 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EMD01226.1 - 6 7.3 9.6 15 6.1 9.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4746 PF15928.5 EMD01226.1 - 6.9 6.0 6.5 17 4.7 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) VPS9 PF02204.18 EMD01227.1 - 1.8e-29 102.0 0.0 3.6e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EMD01227.1 - 5.4e-16 58.7 0.4 1.6e-15 57.2 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EMD01227.1 - 2.9e-11 42.8 0.1 1.3e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 CUE domain DUF4355 PF14265.6 EMD01227.1 - 2.3 8.5 7.3 6.1 7.1 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DCB PF16213.5 EMD01228.1 - 2.8e-42 144.4 2.8 2.8e-42 144.4 2.8 2.7 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EMD01228.1 - 2.2e-32 112.1 1.4 2.5e-31 108.7 0.0 3.3 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EMD01228.1 - 1e-11 43.8 0.0 9.2e-10 37.3 0.0 2.7 3 0 0 3 3 3 2 C-terminal region of Mon2 protein Ribonuc_P_40 PF08584.11 EMD01229.1 - 1.5e-18 67.1 0.0 1.8e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit MFS_1 PF07690.16 EMD01230.1 - 1.2e-40 139.5 45.7 4.6e-40 137.6 44.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EMD01230.1 - 8e-05 21.7 13.5 8e-05 21.7 13.5 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter V_ATPase_I PF01496.19 EMD01230.1 - 0.025 12.5 0.0 0.036 12.0 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family adh_short PF00106.25 EMD01231.1 - 1.8e-27 96.1 0.1 1.9e-26 92.7 0.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EMD01231.1 - 6.2e-16 58.7 0.2 1.8e-14 53.9 0.2 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EMD01231.1 - 1.2e-10 41.6 0.2 2.1e-09 37.6 0.2 2.1 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EMD01231.1 - 4.5e-05 23.4 0.2 7.9e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EMD01231.1 - 0.00038 19.8 0.0 0.00065 19.0 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EMD01231.1 - 0.0091 15.4 0.0 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EMD01231.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EMD01231.1 - 0.019 15.4 0.1 0.034 14.6 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 EMD01231.1 - 0.035 14.7 0.2 0.095 13.3 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 EMD01231.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 EMD01231.1 - 0.07 13.0 0.3 0.21 11.4 0.3 1.9 1 1 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 EMD01231.1 - 0.073 12.7 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EMD01231.1 - 0.11 12.4 0.1 3.7 7.5 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cid2 PF09774.9 EMD01233.1 - 2e-54 184.4 0.0 2.3e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DUF4121 PF13497.6 EMD01233.1 - 0.069 12.3 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) DNA_ligase_A_M PF01068.21 EMD01234.1 - 4.2e-58 196.4 0.3 2e-45 155.0 0.1 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EMD01234.1 - 1.8e-44 152.1 0.1 3.2e-44 151.3 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EMD01234.1 - 2.3e-27 95.5 0.8 8.9e-27 93.6 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Mito_carr PF00153.27 EMD01236.1 - 6.3e-52 173.5 6.2 1.1e-17 63.8 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 EMD01237.1 - 2.2e-19 69.6 47.8 6.1e-19 68.1 39.9 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EMD01237.1 - 0.0016 17.8 19.5 0.0026 17.1 19.5 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Pyr_redox_2 PF07992.14 EMD01238.1 - 3.6e-31 108.5 0.6 4.7e-31 108.1 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EMD01238.1 - 4.8e-11 43.1 1.6 1.2e-10 41.8 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EMD01238.1 - 6.4e-06 25.6 0.2 8.8e-06 25.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EMD01238.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EMD01238.1 - 0.048 12.9 0.2 2.8 7.1 0.2 2.4 2 0 0 2 2 2 0 Thi4 family HAT PF02184.16 EMD01239.1 - 2.7e-21 75.2 67.8 1.3e-14 53.9 3.0 13.2 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 EMD01239.1 - 7e-15 55.3 0.1 0.00021 21.7 0.0 6.5 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EMD01239.1 - 7e-14 51.3 21.4 0.0024 18.5 0.1 11.1 7 2 6 13 13 13 3 Tetratricopeptide repeat Suf PF05843.14 EMD01239.1 - 3.4e-10 40.4 16.8 0.0099 15.9 0.5 6.3 5 2 1 6 6 6 4 Suppressor of forked protein (Suf) TPR_2 PF07719.17 EMD01239.1 - 2.6e-09 36.5 11.9 0.28 11.4 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EMD01239.1 - 1.5e-08 34.5 0.0 2.6 8.6 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EMD01239.1 - 3.9e-05 23.5 6.4 0.74 10.2 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EMD01239.1 - 0.0002 21.9 8.0 0.59 10.8 0.0 6.2 7 1 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EMD01239.1 - 0.00038 20.5 5.2 0.38 10.9 0.0 4.4 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat NRDE-2 PF08424.10 EMD01239.1 - 0.0019 17.4 13.4 0.03 13.4 0.2 4.8 2 2 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 EMD01239.1 - 0.0026 17.0 13.0 0.45 9.7 0.5 4.9 3 2 1 5 5 5 2 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EMD01239.1 - 0.0044 17.1 15.6 0.12 12.5 1.4 6.2 6 2 1 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_1 PF00515.28 EMD01239.1 - 0.024 14.4 2.5 33 4.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EMD01239.1 - 2.9 8.2 16.2 20 5.5 0.1 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat Arf PF00025.21 EMD01241.1 - 6.6e-80 266.7 0.1 7.7e-80 266.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EMD01241.1 - 3e-14 53.2 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EMD01241.1 - 5.1e-14 52.1 0.0 6.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EMD01241.1 - 2.5e-13 49.9 1.4 2e-09 37.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EMD01241.1 - 8.2e-13 48.3 0.0 8.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EMD01241.1 - 1.7e-10 40.7 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EMD01241.1 - 4.1e-06 26.8 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EMD01241.1 - 0.011 15.1 0.7 0.026 13.8 0.7 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Leo1 PF04004.13 EMD01242.1 - 5.8e-37 127.1 0.0 1.7e-36 125.5 0.0 1.9 1 0 0 1 1 1 1 Leo1-like protein SLX9 PF15341.6 EMD01242.1 - 0.049 14.0 2.4 0.19 12.2 2.4 2.0 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Mob1_phocein PF03637.17 EMD01243.1 - 1.3e-37 129.4 0.0 2.5e-37 128.5 0.0 1.4 1 1 0 1 1 1 1 Mob1/phocein family U71 PF17474.2 EMD01243.1 - 0.028 14.3 0.1 0.061 13.3 0.1 1.5 1 0 0 1 1 1 0 Tegument protein UL11 homolog DNA_pol_B_palm PF14792.6 EMD01244.1 - 3.1e-33 114.4 0.0 5.5e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EMD01244.1 - 3.4e-22 78.4 0.0 3.3e-21 75.2 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 EMD01244.1 - 1.3e-19 70.3 0.3 3.6e-19 68.9 0.3 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EMD01244.1 - 9.5e-18 63.8 0.0 1.9e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.23 EMD01244.1 - 3e-05 24.2 0.0 7.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCT PF00533.26 EMD01244.1 - 0.00018 21.8 0.0 0.001 19.4 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EMD01244.1 - 0.018 14.9 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain Sld5 PF05916.11 EMD01245.1 - 6.1e-12 46.0 0.0 9.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein AreA_N PF07573.11 EMD01245.1 - 0.15 12.7 1.1 0.33 11.6 0.3 1.8 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus Red1 PF07964.11 EMD01246.1 - 0.11 10.7 2.1 0.13 10.5 2.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Prefoldin_2 PF01920.20 EMD01247.1 - 1.6e-17 63.4 4.7 2e-17 63.1 4.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit T6PP_N PF18572.1 EMD01247.1 - 0.00048 19.9 3.9 0.00074 19.3 3.9 1.3 1 1 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain GvpG PF05120.12 EMD01247.1 - 0.00062 19.7 1.0 0.0019 18.2 0.0 2.0 2 1 0 2 2 2 1 Gas vesicle protein G DUF3584 PF12128.8 EMD01247.1 - 0.0065 14.1 2.5 0.0082 13.7 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF812 PF05667.11 EMD01247.1 - 0.032 13.1 6.2 0.054 12.4 6.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.9 EMD01247.1 - 0.053 13.8 1.6 0.053 13.8 1.6 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin PF02996.17 EMD01247.1 - 0.06 13.3 0.5 0.06 13.3 0.5 2.1 2 0 0 2 2 2 0 Prefoldin subunit T7SS_ESX_EspC PF10824.8 EMD01247.1 - 0.087 13.3 0.1 0.27 11.7 0.0 1.8 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Spc24 PF08286.11 EMD01247.1 - 0.15 12.3 6.7 0.29 11.4 1.7 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4200 PF13863.6 EMD01247.1 - 0.38 11.2 8.0 0.74 10.2 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CCDC-167 PF15188.6 EMD01247.1 - 0.75 10.2 4.5 0.86 10.0 2.0 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 EMD01247.1 - 2.4 8.8 7.9 0.64 10.7 0.2 2.3 2 1 0 2 2 2 0 SlyX Fib_alpha PF08702.10 EMD01247.1 - 2.9 8.1 7.4 1.7 8.8 0.9 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ceramidase PF05875.12 EMD01248.1 - 4.9e-105 350.7 6.3 5.6e-105 350.5 6.3 1.0 1 0 0 1 1 1 1 Ceramidase DUF4199 PF13858.6 EMD01248.1 - 0.74 10.2 10.0 16 5.8 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Fungal_trans PF04082.18 EMD01250.1 - 4.6e-27 94.7 1.2 7.9e-27 93.9 0.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EMD01250.1 - 8.5e-05 22.6 15.5 0.00016 21.8 15.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1664 PF07889.12 EMD01251.1 - 3.8 7.6 13.0 2.5 8.2 0.6 4.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Metallophos PF00149.28 EMD01252.1 - 8.8e-16 59.0 0.0 1.6e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EMD01252.1 - 6.1e-09 36.3 0.2 5.5e-08 33.2 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 EMD01254.1 - 2.2e-56 191.1 0.0 3.1e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EMD01254.1 - 1.4e-31 109.7 0.0 6.4e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EMD01254.1 - 0.009 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EMD01254.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SIR2 PF02146.17 EMD01255.1 - 1.9e-58 197.3 0.0 2.8e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EMD01255.1 - 2e-06 27.7 0.0 4.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EMD01255.1 - 0.00094 18.9 0.0 0.51 10.1 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain UvrC_HhH_N PF08459.11 EMD01255.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Apq12 PF12716.7 EMD01256.1 - 1.1e-16 60.5 12.0 1.6e-16 60.0 12.0 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis tRNA_lig_CPD PF08302.11 EMD01257.1 - 1.3e-83 280.4 0.0 2.1e-83 279.7 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 EMD01257.1 - 3.6e-83 278.8 0.0 6.5e-83 277.9 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EMD01257.1 - 3.1e-55 186.8 0.1 5.8e-55 185.9 0.1 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 EMD01257.1 - 0.055 14.0 0.3 0.44 11.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EMD01257.1 - 0.082 13.4 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Virulence_fact PF13769.6 EMD01257.1 - 0.085 13.1 0.3 0.56 10.5 0.0 2.5 3 0 0 3 3 3 0 Virulence factor Pesticin PF16754.5 EMD01258.1 - 0.056 13.4 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term Rcd1 PF04078.13 EMD01259.1 - 1.5e-124 414.4 1.7 1.8e-124 414.2 1.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Med15 PF09606.10 EMD01259.1 - 0.64 8.6 19.5 0.75 8.4 19.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.12 EMD01259.1 - 0.75 8.7 5.1 1 8.2 5.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 EMD01259.1 - 7.4 6.5 14.5 9.6 6.1 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L1 PF00687.21 EMD01260.1 - 4.3e-46 157.2 0.5 5e-46 157.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family WH2 PF02205.20 EMD01263.1 - 1.7e-09 37.2 1.1 2.6e-08 33.4 0.6 2.5 2 0 0 2 2 2 1 WH2 motif SUIM_assoc PF16619.5 EMD01264.1 - 0.053 13.6 0.1 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Rhomboid PF01694.22 EMD01265.1 - 1.3e-22 80.4 9.7 2.3e-22 79.6 9.7 1.3 1 0 0 1 1 1 1 Rhomboid family Peptidase_M50B PF13398.6 EMD01269.1 - 2.4e-59 200.3 18.9 3e-59 200.0 18.9 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 EMD01269.1 - 0.068 12.4 0.4 0.14 11.4 0.4 1.4 1 0 0 1 1 1 0 Peptidase family M50 Patched PF02460.18 EMD01269.1 - 4.3 5.3 6.0 7.7 4.4 6.0 1.3 1 0 0 1 1 1 0 Patched family p450 PF00067.22 EMD01271.1 - 2.9e-74 250.5 0.0 3.6e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DBR1 PF05011.13 EMD01271.1 - 0.048 14.1 1.8 9.3 6.7 0.0 2.6 3 0 0 3 3 3 0 Lariat debranching enzyme, C-terminal domain LIM PF00412.22 EMD01272.1 - 3.2e-25 88.1 30.0 3.8e-09 36.6 1.7 4.1 4 0 0 4 4 4 3 LIM domain NfI_DNAbd_pre-N PF10524.9 EMD01274.1 - 0.27 11.1 2.0 22 5.0 0.0 4.2 4 1 1 5 5 5 0 Nuclear factor I protein pre-N-terminus PITH PF06201.13 EMD01275.1 - 5.8e-45 153.2 0.0 7e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 EMD01275.1 - 0.046 13.7 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal BTB PF00651.31 EMD01277.1 - 1.1e-05 25.6 0.0 2.5e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 EMD01280.1 - 0.0027 17.9 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CUE PF02845.16 EMD01281.1 - 1.1e-08 34.6 0.0 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain HA2 PF04408.23 EMD01282.1 - 5e-18 65.4 0.2 1.1e-17 64.2 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EMD01282.1 - 2e-11 44.2 0.0 3.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EMD01282.1 - 2.2e-10 40.7 0.0 4.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EMD01282.1 - 1.4e-05 25.4 0.0 3.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EMD01282.1 - 4e-05 23.5 0.0 8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EMD01282.1 - 0.00073 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EMD01282.1 - 0.00076 19.8 0.0 0.0023 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EMD01282.1 - 0.032 13.8 0.1 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EMD01282.1 - 0.038 14.0 0.1 2.3 8.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EMD01282.1 - 0.043 14.0 0.1 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EMD01282.1 - 0.18 12.3 0.1 0.35 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EMD01282.1 - 0.2 11.3 0.3 0.48 10.0 0.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Herpes_ori_bp PF02399.15 EMD01282.1 - 0.21 9.6 0.0 0.3 9.1 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein BTB PF00651.31 EMD01283.1 - 3.1e-07 30.6 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EMD01284.1 - 0.00056 20.1 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Spem1 PF15670.5 EMD01284.1 - 0.51 9.9 2.7 0.64 9.5 2.7 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Cupin_8 PF13621.6 EMD01287.1 - 7.3e-20 71.7 0.0 9e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EMD01287.1 - 0.031 13.7 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 EMD01287.1 - 0.18 11.6 0.0 0.62 9.8 0.0 1.8 2 0 0 2 2 2 0 Cupin domain ADH_N PF08240.12 EMD01288.1 - 1.4e-33 115.0 1.8 2.7e-33 114.1 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EMD01288.1 - 3.8e-15 56.0 0.0 6.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EMD01288.1 - 3.5e-08 33.2 0.1 5.5e-08 32.5 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EMD01288.1 - 5.6e-06 27.4 0.0 9.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EMD01288.1 - 0.017 14.4 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 EMD01288.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EMD01288.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AMP-binding PF00501.28 EMD01289.1 - 1.2e-69 234.9 0.0 1.5e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EMD01289.1 - 3.1e-05 24.9 0.0 6.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HET PF06985.11 EMD01290.1 - 3.6e-14 53.3 1.1 8.8e-13 48.8 0.0 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CorA PF01544.18 EMD01291.1 - 4.5e-13 49.2 0.1 8.1e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Com_YlbF PF06133.11 EMD01291.1 - 0.15 12.6 2.0 38 4.9 0.0 2.6 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA RXT2_N PF08595.11 EMD01292.1 - 1.1e-37 129.4 0.0 2.5e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 RXT2-like, N-terminal FAD_binding_3 PF01494.19 EMD01293.1 - 8.1e-08 31.9 0.3 0.00073 18.9 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 EMD01293.1 - 6e-06 26.1 0.1 0.0055 16.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EMD01293.1 - 6.2e-06 25.7 0.2 0.0092 15.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EMD01293.1 - 0.0022 17.2 0.4 0.0042 16.2 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EMD01293.1 - 0.0031 16.9 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EMD01293.1 - 0.0049 16.3 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EMD01293.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EMD01293.1 - 0.015 15.8 0.2 0.1 13.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.28 EMD01294.1 - 5.9e-88 296.0 0.0 8.1e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EMD01294.1 - 0.0004 20.3 0.3 0.0048 16.8 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EMD01294.1 - 0.018 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family HET PF06985.11 EMD01295.1 - 2.3e-26 92.9 0.1 3.5e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APS_kinase PF01583.20 EMD01296.1 - 2.8e-72 241.8 0.0 3.4e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EMD01296.1 - 8.5e-05 22.7 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EMD01296.1 - 0.00013 21.6 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EMD01296.1 - 0.0063 17.1 0.0 0.0098 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EMD01296.1 - 0.034 14.5 0.1 0.052 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EMD01296.1 - 0.047 13.4 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 EMD01296.1 - 0.12 11.5 0.2 0.23 10.6 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit GCV_T PF01571.21 EMD01298.1 - 1.3e-74 250.8 0.0 1.7e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EMD01298.1 - 1.2e-21 76.4 0.6 2.1e-21 75.6 0.6 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.8 EMD01298.1 - 0.071 13.0 0.3 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) V-ATPase_C PF03223.15 EMD01299.1 - 1.7e-124 416.0 0.0 1.9e-124 415.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C ALIX_LYPXL_bnd PF13949.6 EMD01299.1 - 0.0056 16.0 0.6 0.0094 15.3 0.6 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV APG6_N PF17675.1 EMD01299.1 - 0.026 15.0 4.5 1.4 9.4 0.2 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region mRNA_cap_C PF03919.15 EMD01299.1 - 0.059 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain PhoD PF09423.10 EMD01300.1 - 9.8e-06 24.8 0.4 0.0011 18.0 0.1 2.8 3 0 0 3 3 3 2 PhoD-like phosphatase Caudo_bapla_RBP PF08931.10 EMD01302.1 - 0.12 11.9 0.2 6.8 6.1 0.1 2.1 2 0 0 2 2 2 0 Receptor-binding protein of phage tail base-plate Siphoviridae, head DUF4661 PF15576.6 EMD01302.1 - 4.2 7.2 6.5 4.7 7.0 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Acetyltransf_1 PF00583.25 EMD01303.1 - 6.7e-08 32.8 0.0 9.9e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EMD01303.1 - 1.9e-07 31.1 0.1 9.5e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EMD01303.1 - 7e-07 29.6 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EMD01303.1 - 7e-06 25.9 0.0 1.6e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EMD01303.1 - 0.0033 17.5 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EMD01303.1 - 0.046 14.4 0.1 0.082 13.6 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DAP10 PF07213.11 EMD01304.1 - 6.7e-06 26.0 0.1 1.6e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 DAP10 membrane protein Podoplanin PF05808.11 EMD01304.1 - 0.029 14.5 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 EMD01304.1 - 0.064 14.1 0.4 0.22 12.4 0.1 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 EMD01304.1 - 1.5 8.3 5.4 3 7.3 5.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SKG6 PF08693.10 EMD01305.1 - 0.024 14.1 5.3 0.024 14.1 5.3 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain V-ATPase_H_N PF03224.14 EMD01306.1 - 7.7e-77 258.7 0.2 1.2e-76 258.0 0.2 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EMD01306.1 - 1.5e-35 121.8 0.0 1.5e-34 118.6 0.0 2.4 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 EMD01306.1 - 0.044 13.8 0.0 0.24 11.5 0.0 2.4 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 EMD01306.1 - 0.21 11.3 6.2 1.2 8.9 0.0 3.4 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Sterol-sensing PF12349.8 EMD01307.1 - 1e-37 129.3 10.2 1e-37 129.3 10.2 2.2 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EMD01307.1 - 4.5e-15 54.8 6.1 7.5e-15 54.1 6.1 1.3 1 0 0 1 1 1 1 Patched family Abhydrolase_9_N PF15420.6 EMD01307.1 - 0.052 13.5 0.1 0.052 13.5 0.1 3.3 4 0 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus GN3L_Grn1 PF08701.11 EMD01311.1 - 1.6e-25 89.0 13.7 3.8e-25 87.8 13.7 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase Ycf1 PF05758.12 EMD01311.1 - 0.12 10.2 1.0 0.17 9.7 1.0 1.1 1 0 0 1 1 1 0 Ycf1 DUF4746 PF15928.5 EMD01311.1 - 0.38 10.1 6.5 0.57 9.6 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Myb_DNA-binding PF00249.31 EMD01312.1 - 0.0051 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EMD01312.1 - 0.011 16.0 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain EMP24_GP25L PF01105.24 EMD01314.1 - 9.7e-50 169.0 0.1 1.2e-49 168.8 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4793 PF16041.5 EMD01314.1 - 0.066 13.4 0.3 0.15 12.2 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4793) AAA PF00004.29 EMD01315.1 - 3.7e-84 279.8 0.0 3.3e-41 140.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EMD01315.1 - 8.5e-18 63.9 3.3 3.1e-10 39.7 0.1 3.3 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 EMD01315.1 - 1.8e-12 48.0 0.6 0.00019 21.9 0.0 4.3 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EMD01315.1 - 2.3e-10 40.6 0.2 4.5e-05 23.5 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EMD01315.1 - 4.6e-10 39.9 0.0 0.0018 18.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EMD01315.1 - 3.6e-09 37.0 0.6 0.07 13.4 0.0 4.5 3 2 2 5 5 4 2 AAA domain RuvB_N PF05496.12 EMD01315.1 - 1.2e-08 34.8 0.0 0.0032 17.2 0.0 2.5 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EMD01315.1 - 3.8e-06 26.4 1.3 0.066 12.6 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EMD01315.1 - 4.8e-06 26.8 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EMD01315.1 - 2.7e-05 24.5 0.1 0.39 11.1 0.0 3.2 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EMD01315.1 - 3.4e-05 23.9 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EMD01315.1 - 8.3e-05 21.9 0.0 0.1 11.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 EMD01315.1 - 0.00011 21.9 0.0 0.084 12.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 EMD01315.1 - 0.00012 21.7 0.0 0.41 10.1 0.0 3.1 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EMD01315.1 - 0.00015 21.4 1.1 0.97 9.0 0.0 3.5 2 1 1 3 3 3 2 AAA domain Rad17 PF03215.15 EMD01315.1 - 0.0002 21.3 0.0 0.38 10.6 0.0 2.6 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_28 PF13521.6 EMD01315.1 - 0.00043 20.6 0.0 0.75 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EMD01315.1 - 0.00047 20.7 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EMD01315.1 - 0.00054 19.4 0.0 0.35 10.2 0.0 2.7 3 0 0 3 3 2 1 Bacterial TniB protein AAA_17 PF13207.6 EMD01315.1 - 0.00064 20.2 0.2 0.39 11.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 EMD01315.1 - 0.00077 19.5 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EMD01315.1 - 0.00078 18.9 0.0 1.2 8.4 0.0 2.7 3 0 0 3 3 3 2 KaiC Viral_helicase1 PF01443.18 EMD01315.1 - 0.0016 18.3 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EMD01315.1 - 0.0016 18.3 0.0 1 9.3 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EMD01315.1 - 0.0016 17.9 0.1 0.82 9.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 EMD01315.1 - 0.0019 18.1 0.0 0.79 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EMD01315.1 - 0.0028 17.6 0.1 5.9 6.8 0.0 3.2 2 1 1 3 3 3 0 NACHT domain AAA_24 PF13479.6 EMD01315.1 - 0.0033 17.2 0.0 0.71 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EMD01315.1 - 0.0036 17.0 0.0 1.7 8.3 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain TIP49 PF06068.13 EMD01315.1 - 0.0039 16.5 0.0 0.73 9.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain ABC_tran PF00005.27 EMD01315.1 - 0.0078 16.7 0.0 1.5 9.3 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.13 EMD01315.1 - 0.0084 15.3 0.0 0.33 10.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 EMD01315.1 - 0.012 15.9 0.3 3.4 8.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain SKI PF01202.22 EMD01315.1 - 0.041 14.0 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase NB-ARC PF00931.22 EMD01315.1 - 0.044 13.0 0.0 10 5.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EMD01315.1 - 0.05 13.5 0.0 10 6.0 0.0 3.3 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 EMD01315.1 - 0.05 12.5 0.0 6.7 5.5 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Vps4_C PF09336.10 EMD01315.1 - 0.072 13.1 0.0 0.71 9.9 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain ResIII PF04851.15 EMD01315.1 - 0.098 12.7 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EMD01315.1 - 0.16 11.7 0.2 8.1 6.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain Snf7 PF03357.21 EMD01316.1 - 3.7e-36 124.3 5.2 4.9e-36 123.9 5.2 1.2 1 0 0 1 1 1 1 Snf7 BORCS7 PF16088.5 EMD01316.1 - 0.017 15.4 2.1 0.032 14.5 2.1 1.6 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 HSCB_C PF07743.13 EMD01316.1 - 10 6.7 10.1 4.1 8.0 1.8 3.0 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Baudoinia_panamericana_UAMH10762-Bauco1/GCA_000338955.1_Bauco1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Baudoinia_panamericana_UAMH10762-Bauco1/GCA_000338955.1_Bauco1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Baudoinia_panamericana_UAMH10762-Bauco1/GCA_000338955.1_Bauco1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Baudoinia_panamericana_UAMH10762-Bauco1/GCA_000338955.1_Bauco1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 15:16:13 2019 # [ok]